-- dump date 20140620_054506 -- class Genbank::CDS -- table cds_note -- id note YP_002112883.1 identified by match to protein family HMM PF00717 YP_002112884.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_002112885.1 identified by match to protein family HMM TIGR01552 YP_002112888.1 SopB YP_002112889.1 identified by match to protein family HMM PF00376; match to protein family HMM PF01656 YP_002112890.1 identified by match to protein family HMM PF01051 YP_002112891.1 identified by match to protein family HMM PF08212 YP_002112892.1 identified by match to protein family HMM PF00376 YP_002112893.1 identified by match to protein family HMM PF00576; match to protein family HMM TIGR02962 YP_002112894.1 identified by match to protein family HMM PF04463; match to protein family HMM PF08349 YP_002112895.1 identified by match to protein family HMM PF02463 YP_002112896.1 identified by match to protein family HMM PF00665 YP_002112899.1 Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor YP_002112900.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385 YP_002112901.1 identified by match to protein family HMM PF01695 YP_002112902.1 identified by match to protein family HMM PF00665 YP_002112906.1 identified by match to protein family HMM PF00665 YP_002112907.1 identified by match to protein family HMM PF01527 YP_002112908.1 identified by match to protein family HMM PF00589 YP_002112909.1 identified by match to protein family HMM PF03400 YP_002112910.1 identified by match to protein family HMM PF01526 YP_002112911.1 identified by match to protein family HMM PF00892 YP_002112912.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00880 YP_002112913.1 identified by match to protein family HMM PF00440; match to protein family HMM PF02909 YP_002112915.1 identified by match to protein family HMM PF01526 YP_002112916.1 identified by match to protein family HMM PF01526 YP_002112917.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_002112919.1 identified by match to protein family HMM PF00589; match to protein family HMM TIGR02249 YP_002112920.1 identified by match to protein family HMM PF00665 YP_002112921.1 identified by match to protein family HMM PF00665 YP_002112922.1 identified by match to protein family HMM PF00563 YP_002112923.1 identified by match to protein family HMM PF05052 YP_002112924.1 identified by match to protein family HMM PF00376; match to protein family HMM TIGR02054 YP_002112925.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00403; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR02053 YP_002112926.1 identified by match to protein family HMM PF00144 YP_002112927.1 identified by match to protein family HMM PF00665 YP_002112928.1 identified by glimmer; putative YP_002112929.1 identified by match to protein family HMM PF01243 YP_002112931.1 identified by match to protein family HMM PF01526 YP_002112932.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_002112934.1 identified by match to protein family HMM PF00665 YP_002112936.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002112937.1 identified by glimmer; putative YP_002112938.1 identified by glimmer; putative YP_002112939.1 identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496 YP_002112940.1 identified by match to protein family HMM PF00872 YP_002112941.1 identified by match to protein family HMM PF00893 YP_002112942.1 streptomycin 3'-adenyltransferase YP_002112943.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00710; match to protein family HMM TIGR00880 YP_002112944.1 streptomycin 3'-adenyltransferase YP_002112946.1 identified by match to protein family HMM PF00561 YP_002112947.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM TIGR02249 YP_002112949.1 identified by match to protein family HMM PF00665 YP_002112951.1 identified by match to protein family HMM PF01526 YP_002112953.1 identified by glimmer; putative YP_002112954.1 identified by match to protein family HMM PF03743 YP_002112955.1 identified by match to protein family HMM PF00665 YP_002112957.1 identified by match to protein family HMM PF00665 YP_002112958.1 identified by match to protein family HMM PF01526 YP_002112959.1 identified by match to protein family HMM PF03203 YP_002112960.1 identified by match to protein family HMM PF00403; match to protein family HMM TIGR02052 YP_002112961.1 identified by match to protein family HMM PF02411 YP_002112962.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR02051 YP_002112963.1 identified by match to protein family HMM PF04655 YP_002112964.1 identified by match to protein family HMM PF01636 YP_002112967.1 identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496 YP_002112968.1 identified by match to protein family HMM PF02878 YP_002112969.1 identified by match to protein family HMM PF04986 YP_002112970.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_002112972.1 identified by match to protein family HMM PF00665 YP_002112974.1 identified by match to protein family HMM PF00302 YP_002112975.1 identified by match to protein family HMM PF00665 YP_002112976.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002112979.1 identified by match to protein family HMM PF00072; match to protein family HMM PF08667 YP_002112981.1 identified by glimmer; putative YP_002112982.1 identified by match to protein family HMM PF01464 YP_002112983.1 identified by match to protein family HMM PF04956 YP_002112984.1 identified by match to protein family HMM PF03135; match to protein family HMM PF05101 YP_002112985.1 identified by match to protein family HMM PF07996 YP_002112987.1 identified by match to protein family HMM PF04610 YP_002112989.1 identified by match to protein family HMM PF04335 YP_002112990.1 identified by match to protein family HMM PF03524; match to protein family HMM TIGR02781 YP_002112991.1 identified by match to protein family HMM PF03743 YP_002112992.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR02788 YP_002112997.1 identified by match to protein family HMM PF01131; match to protein family HMM PF01751 YP_002112998.1 identified by match to protein family HMM PF00816 YP_002112999.1 identified by glimmer; putative YP_002113003.1 identified by glimmer; putative YP_002113004.1 identified by match to protein family HMM PF08401 YP_002113005.1 identified by match to protein family HMM PF03090; match to protein family HMM PF08708 YP_002113006.1 identified by glimmer; putative YP_002113008.1 identified by match to protein family HMM PF03389 YP_002113010.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_002113011.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_002113012.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_002113013.1 identified by match to protein family HMM PF03883 YP_002113014.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002113015.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874 YP_002113016.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_002113017.1 identified by match to protein family HMM PF01184 YP_002113018.1 identified by match to protein family HMM PF03667 YP_002113020.1 identified by glimmer YP_002113021.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_002113022.1 'chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion' YP_002113023.1 identified by glimmer YP_002113024.1 identified by match to protein family HMM PF00126 YP_002113026.1 identified by match to protein family HMM PF05838; match to protein family HMM PF09374 YP_002113028.1 identified by match to protein family HMM PF00704; match to protein family HMM PF02839 YP_002113031.1 identified by match to protein family HMM PF00419 YP_002113032.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002113033.1 identified by match to protein family HMM PF00577 YP_002113034.1 identified by match to protein family HMM PF00419 YP_002113035.1 identified by match to protein family HMM PF00419 YP_002113036.1 identified by match to protein family HMM PF00419 YP_002113037.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002113040.1 identified by match to protein family HMM PF00126 YP_002113042.1 identified by glimmer YP_002113043.1 identified by match to protein family HMM PF05935 YP_002113044.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872 YP_002113045.1 identified by match to protein family HMM PF07135 YP_002113046.1 identified by glimmer YP_002113047.1 identified by match to protein family HMM PF00884 YP_002113048.1 identified by match to protein family HMM PF04055 YP_002113050.1 identified by match to protein family HMM PF05935 YP_002113051.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_002113052.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_002113053.1 identified by match to protein family HMM PF01055 YP_002113054.1 identified by match to protein family HMM TIGR00792 YP_002113055.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_002113056.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_002113057.1 'IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme' YP_002113058.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_002113059.1 identified by glimmer YP_002113060.1 identified by match to protein family HMM PF00254 YP_002113061.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_002113062.1 identified by glimmer YP_002113064.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides YP_002113065.1 identified by match to protein family HMM PF00072 YP_002113066.1 identified by match to protein family HMM PF02518 YP_002113067.1 identified by match to protein family HMM PF03977; match to protein family HMM TIGR01109 YP_002113068.1 catalyzes the formation of pyruvate from oxaloacetate YP_002113069.1 catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide YP_002113070.1 identified by match to protein family HMM PF03390; match to protein family HMM TIGR00783 YP_002113071.1 identified by match to protein family HMM PF00583; match to protein family HMM PF08218; match to protein family HMM TIGR00124; match to protein family HMM TIGR00125 YP_002113072.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate YP_002113073.1 identified by match to protein family HMM PF03328; match to protein family HMM TIGR01588 YP_002113074.1 identified by match to protein family HMM PF04223; match to protein family HMM TIGR01584 YP_002113075.1 identified by match to protein family HMM PF03802; match to protein family HMM TIGR03124 YP_002113076.1 identified by match to protein family HMM PF01874; match to protein family HMM TIGR03125 YP_002113077.1 'catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis' YP_002113081.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_002113082.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_002113083.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities YP_002113084.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA YP_002113085.1 identified by match to protein family HMM PF00501 YP_002113086.1 'catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine' YP_002113087.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA YP_002113088.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism YP_002113089.1 identified by glimmer YP_002113091.1 'required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase' YP_002113092.1 involved in electron transfer during carnitine metabolism YP_002113093.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction YP_002113095.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002113096.1 identified by match to protein family HMM PF06004 YP_002113098.1 identified by glimmer YP_002113099.1 identified by match to protein family HMM PF07338 YP_002113100.1 identified by match to protein family HMM PF00884; match to protein family HMM TIGR01409 YP_002113101.1 'Required for full activity of KefC, a potassium-proton antiporter' YP_002113102.1 transport system that facilitates potassium-efflux YP_002113103.1 identified by glimmer YP_002113104.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_002113105.1 'hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP' YP_002113106.1 protein associated with Co2+ and Mg2+ efflux YP_002113107.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_002113108.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_002113109.1 'Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB' YP_002113110.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_002113111.1 identified by glimmer YP_002113112.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_002113113.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs YP_002113114.1 'transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA' YP_002113115.1 'Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C' YP_002113116.1 identified by match to protein family HMM PF02698 YP_002113118.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_002113119.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_002113120.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_002113121.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_002113122.1 identified by match to protein family HMM PF09335 YP_002113123.1 with TbpA and ThiP is part of the thiamine and TPP transport system YP_002113124.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_002113125.1 part of the thiamine and TPP transport system tbpA-thiPQ YP_002113127.1 activates sgrS under glucose-phosphate stress conditions YP_002113128.1 identified by glimmer YP_002113129.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_002113130.1 'dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate' YP_002113131.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_002113132.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_002113133.1 activator for leuABCD operon; member of LysR family of transcriptional activators YP_002113134.1 'catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive' YP_002113135.1 'with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit' YP_002113136.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_002113137.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_002113138.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006 YP_002113139.1 membrane bound cell division protein at septum containing leucine zipper motif YP_002113140.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002113141.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_002113142.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143 YP_002113143.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_002113144.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_002113145.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_002113146.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002113147.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_002113148.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002113149.1 involved in septum formation YP_002113150.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_002113151.1 'GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function' YP_002113152.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_002113153.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_002113154.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586 YP_002113155.1 identified by match to protein family HMM PF03884 YP_002113156.1 identified by match to protein family HMM PF07072 YP_002113157.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_002113158.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_002113159.1 identified by match to protein family HMM PF00482 YP_002113160.1 identified by match to protein family HMM PF00437 YP_002113161.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_002113162.1 'catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide' YP_002113163.1 identified by match to protein family HMM PF01510 YP_002113164.1 involved in regulation of beta-lactamase; signaling protein YP_002113165.1 identified by match to protein family HMM PF04616 YP_002113166.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00792 YP_002113167.1 identified by glimmer YP_002113168.1 identified by match to protein family HMM PF00324 YP_002113169.1 identified by glimmer YP_002113170.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_002113171.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_002113172.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_002113173.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002113174.1 identified by glimmer YP_002113178.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_002113179.1 identified by match to protein family HMM PF06062 YP_002113180.2 transports degraded pectin products into the bacterial cell YP_002113181.1 identified by match to protein family HMM PF07005 YP_002113182.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_002113183.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002113184.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_002113185.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_002113187.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_002113188.1 identified by match to protein family HMM PF01011; match to protein family HMM TIGR03074 YP_002113189.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203 YP_002113190.1 catalyzes the interconversion of bicarbonate and carbon dioxide YP_002113191.1 identified by match to protein family HMM PF00005 YP_002113192.1 identified by match to protein family HMM PF01061 YP_002113193.1 identified by match to protein family HMM PF00419 YP_002113194.1 identified by match to protein family HMM PF00577 YP_002113195.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002113196.1 identified by match to protein family HMM PF00419 YP_002113197.1 identified by glimmer YP_002113198.1 identified by match to protein family HMM PF03610 YP_002113199.1 identified by match to protein family HMM PF01522 YP_002113200.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_002113201.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_002113202.1 'catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate' YP_002113203.1 identified by match to protein family HMM PF00419 YP_002113204.1 identified by match to protein family HMM PF00419 YP_002113207.1 similar to the fimbrial usher protein PapC YP_002113208.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002113209.1 identified by match to protein family HMM PF00419 YP_002113210.1 identified by glimmer YP_002113211.1 'catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP' YP_002113212.2 Polymerase that creates the 3' poly(A) tail found in some mRNA's YP_002113213.1 'this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu' YP_002113214.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02420 YP_002113215.1 Regulatory factor involved in maltose metabolism YP_002113216.1 identified by match to protein family HMM PF02834; match to protein family HMM TIGR02258 YP_002113217.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_002113218.1 'bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell' YP_002113219.1 identified by glimmer YP_002113220.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein YP_002113221.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_002113222.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_002113223.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_002113224.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_002113225.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_002113226.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_002113227.1 identified by match to protein family HMM PF03458 YP_002113228.1 solute binding component of the vitamin B12 transport system BtuCDF YP_002113229.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_002113230.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_002113231.1 protease Do; required at high temperature; degrades damaged proteins YP_002113232.1 'regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization' YP_002113233.1 identified by match to protein family HMM PF03272 YP_002113235.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002113236.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_002113237.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_002113238.1 'catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn' YP_002113239.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_002113240.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_002113241.1 Catalyzes the phosphorylation of UMP to UDP YP_002113242.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_002113243.2 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_002113244.1 catalyzes the formation of UDP pyrophosphate from isopentenyl pyrophosphate YP_002113245.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate YP_002113246.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_002113247.1 'part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins' YP_002113248.1 identified by match to protein family HMM PF03938 YP_002113249.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_002113250.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_002113251.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_002113252.1 'catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM' YP_002113253.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_002113254.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_002113255.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_002113257.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_002113258.1 identified by match to protein family HMM PF00903 YP_002113259.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase YP_002113260.2 identified by match to protein family HMM PF07073 YP_002113261.1 identified by match to protein family HMM PF06786 YP_002113262.1 identified by match to protein family HMM PF07152 YP_002113263.1 identified by match to protein family HMM PF00472 YP_002113264.1 identified by match to protein family HMM PF04170 YP_002113265.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002113266.1 identified by match to protein family HMM PF01980; match to protein family HMM TIGR00104 YP_002113268.1 identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363 YP_002113269.1 part of the MetNIQ methionine uptake system YP_002113270.1 part of the metNIQ transport system for methionine YP_002113271.1 'Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate' YP_002113272.1 'catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid' YP_002113273.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002113274.1 identified by match to protein family HMM PF07690 YP_002113275.1 identified by match to protein family HMM PF03372 YP_002113276.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002113277.2 'catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall' YP_002113278.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione YP_002113279.1 identified by match to protein family HMM PF08241 YP_002113280.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_002113281.1 3'-5' exonuclease of DNA polymerase III YP_002113282.1 identified by match to protein family HMM PF06812 YP_002113283.1 identified by match to protein family HMM PF06996; match to protein family HMM TIGR03347 YP_002113284.1 identified by match to protein family HMM PF05947; match to protein family HMM TIGR03359 YP_002113285.1 identified by match to protein family HMM PF04965; match to protein family HMM TIGR03357 YP_002113286.1 identified by match to protein family HMM PF07024 YP_002113288.1 identified by glimmer YP_002113289.1 identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03345 YP_002113291.1 identified by match to protein family HMM PF05591; match to protein family HMM TIGR03358 YP_002113292.1 identified by match to protein family HMM PF05943; match to protein family HMM TIGR03355 YP_002113294.1 identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344 YP_002113297.1 identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344 YP_002113298.1 identified by match to protein family HMM TIGR03352 YP_002113299.1 identified by match to protein family HMM PF05936; match to protein family HMM TIGR03353 YP_002113300.1 identified by match to protein family HMM PF00691; match to protein family HMM TIGR03349; match to protein family HMM TIGR03350 YP_002113302.1 identified by match to protein family HMM PF06744; match to protein family HMM PF06761; match to protein family HMM TIGR03348 YP_002113306.1 identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361 YP_002113307.1 identified by match to protein family HMM PF08786 YP_002113308.1 identified by glimmer YP_002113310.1 identified by glimmer YP_002113314.1 identified by glimmer YP_002113316.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002113317.1 identified by match to protein family HMM PF00577 YP_002113318.1 identified by match to protein family HMM PF05775 YP_002113319.1 identified by match to protein family HMM PF01522 YP_002113321.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002113323.1 identified by match to protein family HMM PF04449 YP_002113325.1 identified by match to protein family HMM PF07434 YP_002113326.1 identified by match to protein family HMM PF01037 YP_002113327.1 identified by glimmer YP_002113329.1 identified by glimmer YP_002113332.1 identified by glimmer YP_002113333.1 identified by match to protein family HMM PF07813 YP_002113334.1 identified by match to protein family HMM PF00795 YP_002113335.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_002113336.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_002113337.1 identified by match to protein family HMM PF00310 YP_002113338.1 identified by match to protein family HMM PF06104 YP_002113339.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_002113340.1 mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY YP_002113341.1 similar to release factor 1 and 2 YP_002113342.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893 YP_002113343.1 'catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively' YP_002113344.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_002113345.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS YP_002113346.1 identified by match to protein family HMM PF00267 YP_002113348.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_002113349.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_002113350.1 identified by match to protein family HMM PF00589 YP_002113351.1 identified by glimmer YP_002113354.1 identified by glimmer YP_002113355.1 identified by glimmer YP_002113357.1 identified by match to protein family HMM PF01751; match to protein family HMM PF08273 YP_002113358.1 identified by glimmer YP_002113360.1 identified by match to protein family HMM PF04606 YP_002113361.1 identified by glimmer YP_002113362.1 identified by match to protein family HMM PF00004 YP_002113365.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002113366.1 identified by match to protein family HMM PF00419 YP_002113367.1 identified by match to protein family HMM PF00577 YP_002113368.2 identified by match to protein family HMM PF00345 YP_002113372.1 identified by match to protein family HMM PF00563 YP_002113373.1 identified by match to protein family HMM PF00486 YP_002113375.1 identified by match to protein family HMM PF06316; match to protein family HMM TIGR03304 YP_002113379.1 identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845 YP_002113380.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_002113381.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_002113382.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525 YP_002113383.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR02044 YP_002113384.1 identified by match to protein family HMM PF00403 YP_002113385.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002113386.1 identified by match to protein family HMM PF01555 YP_002113387.1 identified by match to protein family HMM PF04851; match to protein family HMM PF08774 YP_002113388.1 identified by match to protein family HMM PF01654 YP_002113389.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_002113391.1 identified by match to protein family HMM PF00165 YP_002113392.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783 YP_002113393.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_002113394.1 identified by match to protein family HMM PF07338 YP_002113395.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF06506; match to protein family HMM TIGR02329 YP_002113396.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_002113397.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_002113398.1 'functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C' YP_002113399.1 'catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent' YP_002113400.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_002113401.1 identified by glimmer YP_002113402.1 identified by glimmer YP_002113403.1 identified by match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_002113404.1 this protein has no known enzymatic function YP_002113405.1 'in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope' YP_002113406.1 identified by match to protein family HMM PF07759 YP_002113409.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002113410.1 identified by match to protein family HMM PF06904 YP_002113411.1 identified by match to protein family HMM PF07690 YP_002113413.1 identified by glimmer YP_002113414.1 identified by match to protein family HMM PF07769 YP_002113415.1 'catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis' YP_002113416.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_002113417.1 identified by glimmer YP_002113418.1 identified by match to protein family HMM PF02639 YP_002113419.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_002113421.1 identified by match to protein family HMM PF07302 YP_002113422.1 identified by match to protein family HMM PF06865 YP_002113423.1 Required for efficient pilin antigenic variation YP_002113424.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_002113425.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers YP_002113426.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity YP_002113427.1 'with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity' YP_002113428.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB YP_002113429.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_002113431.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002113432.1 'cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation' YP_002113433.1 identified by match to protein family HMM PF00128 YP_002113434.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002113435.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP YP_002113436.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_002113438.1 'Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)' YP_002113439.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_002113440.1 'part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane' YP_002113441.1 'forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF' YP_002113443.1 identified by match to protein family HMM PF01844 YP_002113444.1 identified by match to protein family HMM PF03502 YP_002113445.1 identified by glimmer YP_002113447.1 identified by glimmer YP_002113448.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244 YP_002113449.1 'riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil' YP_002113450.1 'RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not' YP_002113451.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_002113452.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_002113453.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_002113454.1 identified by match to protein family HMM PF00248 YP_002113455.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_002113456.1 identified by match to protein family HMM PF00348 YP_002113457.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_002113458.1 Required for the synthesis of the thiazole moiety YP_002113459.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR03255 YP_002113460.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR03226 YP_002113461.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402; match to protein family HMM TIGR03258 YP_002113462.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR03227 YP_002113463.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR03337 YP_002113464.1 catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate YP_002113465.1 catalyzes the degradation of phosphonoacetaldehyde to acetaldehyde and phosphate YP_002113466.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383 YP_002113467.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_002113468.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_002113469.1 identified by match to protein family HMM PF07690 YP_002113470.1 converts protoheme IX and farnesyl diphosphate to heme O YP_002113471.1 identified by match to protein family HMM PF03626; match to protein family HMM TIGR02847 YP_002113472.1 identified by match to protein family HMM PF00510; match to protein family HMM TIGR02842 YP_002113473.1 identified by match to protein family HMM PF00115; match to protein family HMM TIGR02843 YP_002113474.1 identified by match to protein family HMM PF00116; match to protein family HMM PF06481; match to protein family HMM TIGR01433 YP_002113475.1 identified by glimmer YP_002113476.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_002113477.1 'positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress' YP_002113478.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_002113479.1 'hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates' YP_002113480.1 binds and unfolds substrates as part of the ClpXP protease YP_002113481.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR00763 YP_002113482.1 histone-like DNA-binding protein YP_002113483.1 identified by match to protein family HMM PF00639 YP_002113484.1 identified by match to protein family HMM TIGR00426 YP_002113485.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051 YP_002113486.1 'YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His' YP_002113487.1 identified by match to protein family HMM PF00496 YP_002113488.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002113489.1 identified by match to protein family HMM PF00291 YP_002113490.1 identified by match to protein family HMM PF01037 YP_002113491.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002113492.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002113494.1 'indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.' YP_002113495.1 identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836 YP_002113496.1 identified by match to protein family HMM PF02551; match to protein family HMM TIGR00189 YP_002113498.1 identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589 YP_002113499.1 identified by match to protein family HMM PF00563 YP_002113500.1 'RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome' YP_002113501.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_002113503.1 identified by match to protein family HMM PF00132 YP_002113504.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_002113506.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_002113507.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_002113508.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_002113509.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_002113510.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_002113512.1 'PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks' YP_002113513.1 identified by match to protein family HMM PF04304 YP_002113514.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_002113515.1 'catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA' YP_002113516.1 identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103 YP_002113517.1 'involved in a recombinational process of DNA repair, independent of the recBC complex' YP_002113518.1 molecular chaperone YP_002113519.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_002113520.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_002113521.1 identified by match to protein family HMM PF07859 YP_002113522.1 identified by match to protein family HMM PF00294 YP_002113523.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_002113524.1 identified by glimmer YP_002113525.1 identified by match to protein family HMM PF07690 YP_002113526.1 'catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides' YP_002113527.1 identified by match to protein family HMM PF04073; match to protein family HMM TIGR00011 YP_002113528.1 identified by match to protein family HMM PF07446 YP_002113530.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525 YP_002113531.1 activator of copper-responsive regulon genes YP_002113532.1 identified by match to protein family HMM PF01957 YP_002113533.1 identified by match to protein family HMM PF01145 YP_002113534.1 identified by match to protein family HMM PF00005 YP_002113535.1 identified by match to protein family HMM PF03649; match to protein family HMM TIGR00245 YP_002113536.1 identified by match to protein family HMM PF00085 YP_002113537.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002113538.1 identified by match to protein family HMM PF00657 YP_002113539.1 identified by match to protein family HMM PF00005 YP_002113540.1 identified by match to protein family HMM PF02687 YP_002113542.1 identified by match to protein family HMM PF03180 YP_002113543.1 identified by match to protein family HMM PF00005; match to protein family HMM PF09383 YP_002113544.1 identified by match to protein family HMM PF00528 YP_002113545.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_002113546.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_002113547.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162 YP_002113548.1 'catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine' YP_002113549.1 identified by match to protein family HMM PF00160 YP_002113550.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_002113553.1 identified by match to protein family HMM PF04307 YP_002113555.1 'catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate' YP_002113556.1 identified by match to protein family HMM PF00419 YP_002113557.1 identified by match to protein family HMM PF00419 YP_002113558.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002113559.1 identified by match to protein family HMM PF00577 YP_002113561.1 identified by match to protein family HMM PF00419 YP_002113562.1 activates the production of the major fimbrae protein FimA YP_002113567.1 identified by match to protein family HMM PF00589 YP_002113568.1 identified by match to protein family HMM PF04448 YP_002113569.1 identified by glimmer YP_002113571.1 identified by glimmer YP_002113573.1 identified by glimmer YP_002113580.1 identified by glimmer YP_002113581.1 identified by glimmer YP_002113582.1 identified by glimmer YP_002113583.1 identified by glimmer YP_002113584.1 identified by match to protein family HMM PF01381 YP_002113587.1 identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610 YP_002113590.1 identified by glimmer YP_002113596.1 identified by match to protein family HMM PF00959 YP_002113597.1 identified by match to protein family HMM PF04383 YP_002113600.1 identified by match to protein family HMM PF04466; match to protein family HMM TIGR01547 YP_002113602.1 identified by match to protein family HMM PF04233; match to protein family HMM TIGR01641 YP_002113607.1 identified by glimmer YP_002113610.1 identified by glimmer YP_002113612.1 identified by match to protein family HMM PF07679 YP_002113614.1 identified by glimmer YP_002113615.1 identified by glimmer YP_002113616.1 identified by glimmer YP_002113617.1 identified by glimmer YP_002113621.1 identified by match to protein family HMM PF04383 YP_002113623.1 identified by match to protein family HMM TIGR02675 YP_002113624.1 identified by glimmer YP_002113625.1 identified by glimmer YP_002113626.1 identified by match to protein family HMM PF05939 YP_002113627.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600 YP_002113628.1 identified by glimmer YP_002113629.1 identified by match to protein family HMM PF09327 YP_002113631.1 identified by glimmer YP_002113632.1 identified by match to protein family HMM PF00589 YP_002113633.1 identified by glimmer YP_002113634.1 identified by match to protein family HMM PF05930 YP_002113636.1 identified by glimmer YP_002113637.1 identified by glimmer YP_002113641.1 identified by glimmer YP_002113642.1 identified by glimmer YP_002113645.1 identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621 YP_002113647.1 identified by match to protein family HMM PF03589 YP_002113649.1 identified by match to protein family HMM PF05106; match to protein family HMM TIGR01594 YP_002113652.1 identified by glimmer YP_002113653.1 identified by glimmer YP_002113654.1 identified by glimmer YP_002113655.1 identified by match to protein family HMM PF07278 YP_002113656.1 identified by match to protein family HMM PF05876 YP_002113658.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539 YP_002113659.1 identified by match to protein family HMM PF00574 YP_002113662.1 identified by match to protein family HMM PF06763 YP_002113663.1 identified by match to protein family HMM PF06141 YP_002113664.1 identified by match to protein family HMM PF02368 YP_002113665.1 identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674 YP_002113666.1 identified by match to protein family HMM PF06223; match to protein family HMM TIGR01715 YP_002113667.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541 YP_002113668.1 identified by match to protein family HMM PF05939 YP_002113669.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600 YP_002113670.1 identified by match to protein family HMM PF06805 YP_002113671.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327 YP_002113673.1 identified by match to protein family HMM PF03406; match to protein family HMM PF08400 YP_002113674.1 identified by match to protein family HMM PF02413 YP_002113675.1 identified by glimmer YP_002113676.1 identified by match to protein family HMM PF00497 YP_002113677.1 identified by match to protein family HMM PF02586 YP_002113678.1 identified by match to protein family HMM PF03358; match to protein family HMM TIGR02690 YP_002113679.1 identified by match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935 YP_002113680.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR00014 YP_002113682.1 identified by match to protein family HMM PF01527 YP_002113684.1 identified by match to protein family HMM PF00535 YP_002113685.1 identified by match to protein family HMM PF04138 YP_002113687.1 identified by match to protein family HMM PF02518 YP_002113689.1 identified by match to protein family HMM PF00165 YP_002113690.1 Involved in disulfide oxidoreductase activity and electron transport YP_002113691.1 identified by glimmer YP_002113692.1 identified by match to protein family HMM PF07338 YP_002113693.1 identified by match to protein family HMM PF04224 YP_002113695.1 identified by match to protein family HMM PF00324 YP_002113696.1 identified by match to protein family HMM PF00924 YP_002113697.1 identified by glimmer YP_002113698.1 identified by match to protein family HMM PF00657; match to protein family HMM PF03797 YP_002113699.1 identified by match to protein family HMM PF00165 YP_002113701.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity YP_002113702.1 identified by match to protein family HMM PF01648 YP_002113703.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_002113704.1 identified by match to protein family HMM PF00756 YP_002113705.1 identified by match to protein family HMM PF03621 YP_002113706.1 'with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin' YP_002113707.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake YP_002113708.1 with FepBDE is involved in the transport of ferric enterobactin YP_002113709.1 with FepBCD is involved in the transport of ferric enterobactin YP_002113710.1 with FepBCG is involved in the transport of ferric enterobactin YP_002113711.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters YP_002113712.1 with FepCDG is involved in the transport of ferric enterobactin YP_002113713.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543 YP_002113714.1 'bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate' YP_002113715.1 identified by match to protein family HMM PF00550; match to protein family HMM PF00857 YP_002113716.1 'catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin' YP_002113717.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_002113718.1 identified by match to protein family HMM PF02554 YP_002113719.1 identified by match to protein family HMM PF04328 YP_002113720.1 member of the iron-containing alcohol dehydrogenase family; unknown function YP_002113721.1 catalyzes the transfer of an amino moiety YP_002113722.1 identified by match to protein family HMM PF02195 YP_002113723.1 identified by match to protein family HMM PF01507 YP_002113724.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002113725.1 Involved in disulfide bond formation YP_002113726.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate YP_002113727.1 identified by match to protein family HMM PF06192 YP_002113728.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409 YP_002113729.1 identified by match to protein family HMM PF00037 YP_002113732.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002113733.1 'Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation' YP_002113735.1 identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785 YP_002113736.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA YP_002113737.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate YP_002113738.1 identified by match to protein family HMM PF04223; match to protein family HMM TIGR01584 YP_002113739.1 identified by match to protein family HMM PF03328; match to protein family HMM TIGR01588 YP_002113740.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate YP_002113741.1 identified by match to protein family HMM PF00583; match to protein family HMM PF08218; match to protein family HMM TIGR00124; match to protein family HMM TIGR00125 YP_002113742.1 identified by match to protein family HMM PF02518 YP_002113743.1 regulates the expression of citAB in citrate fermentation YP_002113744.1 responsible for the transport of C4-dicarboxylates during anaerobic growth YP_002113745.1 catalyzes the transfer of palmitate to lipid A YP_002113746.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_002113747.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_002113748.1 identified by match to protein family HMM PF00795 YP_002113749.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_002113750.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_002113751.1 identified by glimmer YP_002113752.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002113753.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_002113754.1 identified by match to protein family HMM PF04359 YP_002113755.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_002113756.1 identified by match to protein family HMM PF03330; match to protein family HMM PF05036; match to protein family HMM TIGR00413 YP_002113757.1 identified by match to protein family HMM PF01098; match to protein family HMM TIGR02210 YP_002113758.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM TIGR03423 YP_002113759.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_002113760.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090 YP_002113761.1 identified by match to protein family HMM PF00300; match to protein family HMM TIGR03162 YP_002113762.1 'cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase' YP_002113763.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_002113764.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_002113765.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane YP_002113766.1 'leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase' YP_002113767.1 identified by match to protein family HMM PF08666 YP_002113768.1 identified by match to protein family HMM PF04295 YP_002113769.1 transports degraded pectin products into the bacterial cell YP_002113770.1 identified by match to protein family HMM PF00158; match to protein family HMM PF06506 YP_002113771.1 identified by match to protein family HMM PF07295 YP_002113772.1 'Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific' YP_002113773.1 identified by match to protein family HMM PF00005 YP_002113774.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002113775.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002113776.1 identified by match to protein family HMM PF00497 YP_002113777.1 Transfers the fatty acyl group on membrane lipoproteins YP_002113778.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471 YP_002113779.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043 YP_002113780.1 identified by match to protein family HMM PF02562 YP_002113781.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_002113782.1 'catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q' YP_002113783.1 identified by match to protein family HMM PF00665 YP_002113785.1 'functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP' YP_002113786.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01460 YP_002113787.1 identified by match to protein family HMM PF00480 YP_002113788.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_002113789.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_002113790.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002113791.1 'catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA' YP_002113792.1 identified by glimmer YP_002113793.1 identified by match to protein family HMM PF03573 YP_002113795.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_002113796.1 identified by match to protein family HMM TIGR02484 YP_002113797.1 catalyzes the oxidation of tricarballylate to cis-aconitate; FAD-dependent; required for the utilization of tricarballylate as a carbon and energy source by S. enterica YP_002113798.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002113799.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_002113800.2 'An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group' YP_002113801.1 identified by match to protein family HMM PF01402 YP_002113802.1 identified by glimmer YP_002113803.1 identified by match to protein family HMM PF00561; match to protein family HMM PF07819 YP_002113804.1 negative modulator of the initiation of chromosome replication YP_002113805.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_002113807.1 'catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system' YP_002113808.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_002113810.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport YP_002113811.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_002113812.1 'One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex' YP_002113813.1 'One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions' YP_002113814.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002113816.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_002113817.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_002113818.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486 YP_002113819.1 identified by match to protein family HMM PF02682; match to protein family HMM TIGR00370 YP_002113820.1 identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724 YP_002113821.1 identified by match to protein family HMM PF03746 YP_002113823.1 identified by match to protein family HMM PF00589 YP_002113825.1 identified by glimmer YP_002113826.1 identified by match to protein family HMM PF03275; match to protein family HMM TIGR00031 YP_002113827.1 identified by match to protein family HMM PF00535 YP_002113828.1 identified by match to protein family HMM PF00534 YP_002113829.1 identified by match to protein family HMM PF01061 YP_002113830.1 identified by match to protein family HMM PF00005 YP_002113835.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity YP_002113836.1 identified by match to protein family HMM PF05145; match to protein family HMM TIGR03082 YP_002113837.1 'type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH' YP_002113838.1 identified by match to protein family HMM PF01127; match to protein family HMM TIGR02970 YP_002113839.1 identified by match to protein family HMM TIGR02968 YP_002113840.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_002113841.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_002113842.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_002113843.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_002113844.1 catalyzes the interconversion of succinyl-CoA and succinate YP_002113845.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_002113846.1 identified by glimmer YP_002113847.1 identified by glimmer YP_002113848.1 identified by match to protein family HMM PF01654 YP_002113849.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_002113850.1 identified by match to protein family HMM PF08173; match to protein family HMM TIGR02106 YP_002113851.1 identified by match to protein family HMM PF09600; match to protein family HMM TIGR02112 YP_002113852.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_002113853.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_002113854.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_002113855.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_002113856.1 identified by match to protein family HMM PF00691; match to protein family HMM TIGR02802 YP_002113857.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity YP_002113858.2 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_002113859.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528 YP_002113860.1 involved in zinc efflux across the cytoplasmic membrane YP_002113862.1 'catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive' YP_002113863.1 identified by match to protein family HMM PF01032 YP_002113864.1 identified by match to protein family HMM PF00005 YP_002113865.1 '2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate' YP_002113866.1 'catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose' YP_002113867.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_002113868.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_002113869.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179 YP_002113871.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_002113872.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_002113874.1 with ModCB is involved in the high-affinity transport of molybdate YP_002113875.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_002113876.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_002113877.1 'YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily' YP_002113878.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate YP_002113879.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family YP_002113880.1 'catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway' YP_002113881.1 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate YP_002113882.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02018 YP_002113883.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_002113884.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_002113885.1 YbhB; similar to rat and human kinase inhibitory proteins YP_002113886.1 'catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate' YP_002113887.1 identified by match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR00433 YP_002113888.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_002113889.1 'methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth' YP_002113890.1 'DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium' YP_002113891.1 'The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion' YP_002113893.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826 YP_002113894.1 'together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z' YP_002113895.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR02667 YP_002113896.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_002113897.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_002113898.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_002113899.1 identified by match to protein family HMM PF01027 YP_002113903.1 identified by match to protein family HMM PF00614 YP_002113904.1 identified by match to protein family HMM PF03372 YP_002113906.1 identified by match to protein family HMM PF01061 YP_002113907.1 identified by match to protein family HMM PF01061 YP_002113908.1 identified by match to protein family HMM PF00005 YP_002113909.1 identified by match to protein family HMM PF00529 YP_002113910.1 identified by match to protein family HMM PF00440; match to protein family HMM PF09209 YP_002113911.1 this helicase is not essential cell growth YP_002113912.1 helicase involved in DNA repair and perhaps also replication YP_002113913.1 identified by match to protein family HMM PF02885 YP_002113914.1 identified by match to protein family HMM PF07338 YP_002113915.1 identified by glimmer YP_002113916.1 identified by match to protein family HMM PF01258 YP_002113917.1 identified by match to protein family HMM PF05971 YP_002113918.1 identified by match to protein family HMM PF00924 YP_002113919.1 similar to ATP-binding component of ABC transporters YP_002113920.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_002113921.1 similar to periplasmic-binding component of ABC transporters YP_002113922.1 identified by glimmer YP_002113923.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_002113925.1 identified by match to protein family HMM PF00892 YP_002113926.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_002113927.1 identified by match to protein family HMM PF00884 YP_002113929.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present YP_002113930.1 identified by match to protein family HMM PF03734 YP_002113931.1 identified by match to protein family HMM PF00005 YP_002113932.1 identified by match to protein family HMM PF07350 YP_002113933.1 identified by glimmer YP_002113934.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002113935.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774 YP_002113936.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494 YP_002113937.1 'ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase' YP_002113938.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_002113939.1 identified by match to protein family HMM PF01112 YP_002113940.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains YP_002113941.1 identified by match to protein family HMM PF00496 YP_002113942.1 identified by match to protein family HMM PF00528 YP_002113943.1 identified by match to protein family HMM PF00528 YP_002113944.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_002113945.1 'BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing' YP_002113947.2 identified by match to protein family HMM PF01012 YP_002113948.1 identified by match to protein family HMM PF00766; match to protein family HMM PF01012 YP_002113950.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028 YP_002113951.1 identified by match to protein family HMM PF01266; match to protein family HMM PF05187 YP_002113952.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002113954.1 identified by match to protein family HMM PF03811; match to protein family HMM PF07995 YP_002113955.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_002113956.2 'penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains' YP_002113957.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002113958.1 identified by match to protein family HMM PF01569 YP_002113959.1 identified by match to protein family HMM PF07690 YP_002113960.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002113961.1 identified by match to protein family HMM PF07690 YP_002113962.1 identified by match to protein family HMM PF00440 YP_002113963.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625 YP_002113965.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_002113966.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function YP_002113967.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds YP_002113968.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 YP_002113970.1 identified by match to protein family HMM PF01547 YP_002113971.1 part of the PotFGHI ATP-dependent putrescine transporter YP_002113972.1 identified by match to protein family HMM PF00528 YP_002113973.1 identified by match to protein family HMM PF00528 YP_002113975.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_002113977.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002113978.1 identified by match to protein family HMM PF00884 YP_002113980.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_002113981.1 with ArtPQJI acts to transport arginine across the inner membrane YP_002113982.1 with ArtPMJI transports arginine across the inner membrane YP_002113983.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_002113984.1 With ArtMQJI transports arginine across the inner membrane YP_002113985.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS YP_002113986.1 identified by match to protein family HMM PF01906 YP_002113987.1 identified by match to protein family HMM PF01510 YP_002113988.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_002113989.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF05368 YP_002113990.1 'low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine' YP_002113991.1 catalyzes the formation of acetate from pyruvate YP_002113992.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970 YP_002113993.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_002113995.1 identified by match to protein family HMM PF03956 YP_002113997.1 identified by match to protein family HMM PF04393 YP_002113998.1 confers macrolide resistance via active drug efflux YP_002113999.1 with MacA is involved in the export of macrolide YP_002114000.1 identified by match to protein family HMM PF00313; match to protein family HMM TIGR02381 YP_002114001.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_002114002.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates YP_002114003.1 identified by match to protein family HMM PF00857 YP_002114004.1 identified by match to protein family HMM PF02678; match to protein family HMM PF05726 YP_002114005.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002114006.1 'stimulates the activities of the other two initiation factors, IF-2 and IF-3' YP_002114007.1 'leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys' YP_002114008.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_002114009.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_002114010.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding YP_002114011.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_002114012.1 DNA-binding membrane protein required for chromosome resolution and partitioning YP_002114013.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_002114014.1 identified by match to protein family HMM PF00004 YP_002114015.1 'catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA' YP_002114016.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_002114017.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_002114018.1 identified by match to protein family HMM PF04976 YP_002114019.1 identified by match to protein family HMM PF07690 YP_002114020.1 identified by match to protein family HMM PF00324 YP_002114021.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_002114023.2 identified by glimmer YP_002114024.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_002114025.1 identified by match to protein family HMM PF01226; match to protein family HMM TIGR00790 YP_002114026.1 identified by match to protein family HMM PF02624; match to protein family HMM TIGR00702 YP_002114027.1 identified by match to protein family HMM PF04239 YP_002114028.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_002114029.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_002114030.1 identified by match to protein family HMM PF01435 YP_002114031.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_002114032.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_002114033.1 'This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control' YP_002114034.1 identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361 YP_002114035.1 identified by glimmer YP_002114036.1 involved in the transport of lipid A across the inner membrane YP_002114037.1 'transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate' YP_002114038.1 identified by match to protein family HMM PF06224 YP_002114039.1 identified by match to protein family HMM PF03966 YP_002114040.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_002114042.1 identified by match to protein family HMM PF02698 YP_002114043.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_002114044.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_002114045.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_002114046.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_002114047.1 identified by glimmer YP_002114048.1 identified by match to protein family HMM PF01471 YP_002114049.1 identified by match to protein family HMM PF05951; match to protein family HMM PF08291 YP_002114050.1 identified by match to protein family HMM PF00753 YP_002114051.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002114052.1 identified by match to protein family HMM PF00267 YP_002114053.1 identified by glimmer YP_002114054.1 identified by glimmer YP_002114055.1 'catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA' YP_002114056.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_002114057.1 identified by match to protein family HMM PF01433; match to protein family HMM TIGR02414 YP_002114058.1 'catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors' YP_002114059.1 identified by match to protein family HMM PF07126 YP_002114060.1 identified by match to protein family HMM PF00111; match to protein family HMM PF03473; match to protein family HMM PF03476 YP_002114061.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_002114062.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_002114063.1 identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155 YP_002114064.1 identified by match to protein family HMM PF02470 YP_002114065.1 identified by match to protein family HMM PF03886 YP_002114066.1 identified by glimmer YP_002114067.1 'catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP' YP_002114068.1 identified by match to protein family HMM PF05362 YP_002114069.1 identified by match to protein family HMM PF06303 YP_002114070.1 'OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d' YP_002114071.1 identified by match to protein family HMM PF03846; match to protein family HMM TIGR00623 YP_002114072.1 identified by match to protein family HMM PF04993; match to protein family HMM PF04994 YP_002114073.1 identified by match to protein family HMM PF05976; match to protein family HMM TIGR01666; match to protein family HMM TIGR01667 YP_002114074.1 identified by match to protein family HMM PF03733 YP_002114075.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_002114076.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_002114078.1 identified by match to protein family HMM PF08755; match to protein family HMM TIGR02097 YP_002114080.1 identified by match to protein family HMM PF01161; match to protein family HMM TIGR00481 YP_002114081.1 identified by match to protein family HMM PF00165 YP_002114082.1 catalyzes the hydrolysis of acylphosphate YP_002114083.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs YP_002114084.1 identified by match to protein family HMM PF01027 YP_002114085.1 identified by glimmer YP_002114086.1 identified by match to protein family HMM PF00805 YP_002114087.1 identified by glimmer YP_002114088.1 identified by match to protein family HMM PF07824 YP_002114089.1 identified by match to protein family HMM PF05925 YP_002114091.1 identified by glimmer YP_002114092.1 identified by match to protein family HMM PF03577 YP_002114093.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386 YP_002114094.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced YP_002114095.1 identified by match to protein family HMM PF00576; match to protein family HMM TIGR02962 YP_002114096.1 identified by match to protein family HMM PF01613; match to protein family HMM TIGR02296 YP_002114097.1 identified by match to protein family HMM PF03241; match to protein family HMM TIGR02310 YP_002114098.1 identified by match to protein family HMM PF01047; match to protein family HMM TIGR02337 YP_002114099.1 identified by match to protein family HMM PF01557; match to protein family HMM TIGR02303; match to protein family HMM TIGR02305 YP_002114100.1 identified by match to protein family HMM PF00171; match to protein family HMM TIGR02299 YP_002114101.1 identified by match to protein family HMM PF02900; match to protein family HMM TIGR02298 YP_002114102.1 identified by match to protein family HMM PF02962 YP_002114103.1 identified by match to protein family HMM PF01689; match to protein family HMM TIGR02312 YP_002114104.1 identified by match to protein family HMM PF03328; match to protein family HMM TIGR02311 YP_002114105.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR02332 YP_002114106.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311; match to protein family HMM TIGR02297 YP_002114107.1 identified by match to protein family HMM PF00753 YP_002114109.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA YP_002114110.1 'functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock' YP_002114112.1 identified by match to protein family HMM PF02683 YP_002114113.1 identified by match to protein family HMM PF01323 YP_002114114.1 identified by match to protein family HMM PF00085; match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002114115.1 identified by match to protein family HMM PF00328 YP_002114117.1 stationary phase protein that binds TrpR repressor YP_002114120.1 identified by match to protein family HMM PF00440; match to protein family HMM PF08362 YP_002114121.1 identified by match to protein family HMM PF07007 YP_002114122.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_002114123.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121 YP_002114124.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_002114125.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813 YP_002114126.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_002114127.1 identified by match to protein family HMM PF01344; match to protein family HMM PF07646; match to protein family HMM TIGR03547 YP_002114128.1 identified by match to protein family HMM PF06178 YP_002114129.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002114130.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002114131.1 identified by glimmer YP_002114132.1 identified by match to protein family HMM PF02826 YP_002114133.1 identified by match to protein family HMM PF02811 YP_002114134.1 identified by match to protein family HMM PF06192 YP_002114135.1 identified by match to protein family HMM PF06496 YP_002114136.1 identified by match to protein family HMM PF03783 YP_002114137.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_002114138.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_002114139.1 activates the csgBA and csgDEFG operons involved in biofilm formation YP_002114140.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface YP_002114141.1 identified by match to protein family HMM PF07012 YP_002114142.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers YP_002114143.1 identified by glimmer YP_002114145.1 identified by match to protein family HMM PF01661 YP_002114146.2 identified by match to protein family HMM PF00614 YP_002114147.1 required for the transfer of succinyl residues to the glucan backbone YP_002114148.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_002114149.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_002114150.1 identified by match to protein family HMM PF07119 YP_002114152.1 Confers resistance to fosfomycin and deoxycholate YP_002114153.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_002114154.1 identified by match to protein family HMM PF00581 YP_002114155.1 identified by match to protein family HMM PF04264 YP_002114156.1 identified by match to protein family HMM PF01292 YP_002114159.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_002114160.1 'BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing' YP_002114161.1 identified by match to protein family HMM PF06183 YP_002114162.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_002114163.1 identified by match to protein family HMM PF07273 YP_002114164.1 cofactor involved in the reduction of disulfides YP_002114165.1 Confers resistance to norfloxacin and enoxacin YP_002114166.1 identified by match to protein family HMM PF00583 YP_002114167.1 identified by match to protein family HMM PF04337 YP_002114168.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002114169.1 identified by match to protein family HMM PF03023; match to protein family HMM TIGR01695 YP_002114170.1 identified by match to protein family HMM PF05130 YP_002114171.1 regulates the flagellar specific sigma28 transcription factor YP_002114172.1 required for the assembly of the flagellar basal body P-ring YP_002114173.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_002114174.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_002114175.1 'acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production' YP_002114176.1 the hook connects flagellar basal body to the flagellar filament YP_002114177.1 'FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod' YP_002114178.1 makes up the distal portion of the flagellar basal body rod YP_002114179.1 'part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod' YP_002114180.1 'part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum' YP_002114181.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_002114182.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_002114183.1 'with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes' YP_002114184.1 'bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase' YP_002114185.1 'catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA' YP_002114188.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002114189.1 identified by match to protein family HMM PF02620 YP_002114190.1 identified by glimmer YP_002114191.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_002114192.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_002114193.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128 YP_002114194.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002114195.1 carries the fatty acid chain in fatty acid biosynthesis YP_002114196.1 'FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP' YP_002114197.1 identified by match to protein family HMM PF00419 YP_002114198.1 identified by match to protein family HMM PF00419 YP_002114199.1 identified by match to protein family HMM PF00419 YP_002114200.1 identified by match to protein family HMM PF00577 YP_002114201.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002114202.1 identified by match to protein family HMM PF00419 YP_002114203.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_002114204.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247 YP_002114205.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_002114206.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_002114207.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010 YP_002114208.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002114209.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783 YP_002114210.1 identified by match to protein family HMM PF01230 YP_002114211.1 identified by match to protein family HMM PF07233 YP_002114212.1 identified by match to protein family HMM TIGR02722 YP_002114213.1 catalyzes the phosphorylation of thiamine to thiamine phosphate YP_002114214.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_002114215.1 identified by match to protein family HMM PF05728 YP_002114216.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF07992 YP_002114217.1 identified by match to protein family HMM PF05433 YP_002114218.1 identified by match to protein family HMM PF00440 YP_002114219.1 identified by match to protein family HMM PF07338 YP_002114220.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734 YP_002114221.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580 YP_002114222.1 identified by glimmer YP_002114223.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_002114224.1 'outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone' YP_002114225.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_002114226.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine YP_002114227.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_002114228.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate YP_002114229.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component YP_002114230.1 identified by glimmer YP_002114231.1 translocated by the type III secretion system SPI-2; required for the formation of lysosomal glycoprotein structures (Sifs); required for maintenance of membrane in the Salmonella-containing vacuole; a cysteine residue with CAAX motif is modified by isoprenoid addition of protein geranylgeranyl transferase I; also modified by S-acylation YP_002114233.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component YP_002114234.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase YP_002114235.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_002114236.1 identified by match to protein family HMM PF08007 YP_002114237.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF08918 YP_002114238.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_002114239.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_002114240.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_002114241.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_002114242.1 identified by match to protein family HMM PF00293 YP_002114244.1 identified by match to protein family HMM PF00849; match to protein family HMM TIGR00093 YP_002114245.1 Converts isocitrate to alpha ketoglutarate YP_002114246.1 identified by glimmer YP_002114250.1 identified by match to protein family HMM PF02917 YP_002114251.1 identified by match to protein family HMM PF05838; match to protein family HMM PF09374 YP_002114252.1 identified by match to protein family HMM PF07087 YP_002114253.1 identified by match to protein family HMM PF03372 YP_002114255.1 identified by match to protein family HMM PF06183 YP_002114257.1 identified by match to protein family HMM PF00313 YP_002114261.1 identified by match to protein family HMM PF06316 YP_002114262.1 PliC; periplasmic lysozyme inhibitor of c-type lysozyme YP_002114265.1 identified by match to protein family HMM PF00011 YP_002114267.1 identified by match to protein family HMM PF01292 YP_002114269.1 identified by glimmer YP_002114270.1 identified by glimmer YP_002114271.1 identified by match to protein family HMM PF00496 YP_002114272.1 identified by match to protein family HMM PF00528 YP_002114273.1 identified by match to protein family HMM PF00528 YP_002114274.1 identified by match to protein family HMM PF00005 YP_002114275.1 identified by match to protein family HMM PF00005 YP_002114276.1 identified by match to protein family HMM PF00924 YP_002114277.1 identified by match to protein family HMM PF03860 YP_002114278.1 identified by match to protein family HMM PF09223 YP_002114279.1 streptomycin 3'-adenyltransferase YP_002114280.1 identified by match to protein family HMM PF00196 YP_002114281.1 identified by match to protein family HMM PF00376 YP_002114283.1 catalyzes the interconversion of chorismate to prephenate YP_002114284.1 identified by match to protein family HMM PF01810 YP_002114285.1 identified by match to protein family HMM PF09313 YP_002114286.1 identified by match to protein family HMM PF08956 YP_002114289.1 identified by match to protein family HMM PF04226 YP_002114291.1 identified by match to protein family HMM PF03891 YP_002114293.1 identified by match to protein family HMM PF04343 YP_002114294.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00896 YP_002114295.1 identified by match to protein family HMM PF04284 YP_002114297.1 identified by match to protein family HMM PF04073 YP_002114298.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002114300.1 identified by match to protein family HMM PF04285 YP_002114301.1 identified by glimmer YP_002114302.1 identified by match to protein family HMM PF06798; match to protein family HMM PF08298 YP_002114303.2 identified by match to protein family HMM PF06629 YP_002114305.1 identified by match to protein family HMM PF00248 YP_002114306.1 identified by match to protein family HMM PF01263 YP_002114307.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_002114308.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_002114309.1 identified by match to protein family HMM PF07023 YP_002114310.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_002114311.1 converts asparagine to aspartate and ammonia YP_002114312.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane YP_002114313.1 identified by match to protein family HMM PF00881 YP_002114314.1 catalyzes the formation of selenophosphate from selenide and ATP YP_002114315.1 decatenates replicating daughter chromosomes YP_002114316.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_002114317.1 identified by match to protein family HMM PF07383 YP_002114318.1 identified by match to protein family HMM PF00293 YP_002114319.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_002114321.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate YP_002114322.1 identified by match to protein family HMM PF04958; match to protein family HMM TIGR03243; match to protein family HMM TIGR03244 YP_002114323.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_002114324.1 'catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation' YP_002114325.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_002114327.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP YP_002114328.1 3' incision activity; acts with UvrC YP_002114329.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_002114330.1 identified by glimmer YP_002114331.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_002114332.1 'catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake' YP_002114333.1 'catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake' YP_002114334.1 'catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake' YP_002114335.1 represses the celABCDF-ydjC operon involved in carbon uptake YP_002114336.1 identified by match to protein family HMM PF02056 YP_002114337.1 identified by match to protein family HMM PF04794 YP_002114338.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide YP_002114340.1 identified by match to protein family HMM PF00375 YP_002114341.1 identified by match to protein family HMM PF04307 YP_002114342.1 'YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate' YP_002114344.1 identified by match to protein family HMM PF01636; match to protein family HMM PF03881 YP_002114346.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168 YP_002114347.1 identified by match to protein family HMM PF04338 YP_002114349.1 identified by match to protein family HMM PF01223 YP_002114350.1 'catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA' YP_002114351.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_002114352.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001 YP_002114353.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_002114354.1 'catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily' YP_002114355.1 'catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily' YP_002114356.1 'This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control' YP_002114357.1 with BtuD and BtuF transports vitamin B12 into the cell YP_002114358.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane YP_002114359.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell YP_002114360.1 identified by match to protein family HMM PF00877 YP_002114362.1 identified by match to protein family HMM PF02696 YP_002114364.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_002114365.1 identified by match to protein family HMM PF03618 YP_002114366.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002114367.1 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids YP_002114369.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486 YP_002114370.1 May play a role in a redox process YP_002114371.1 'YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain' YP_002114372.1 identified by match to protein family HMM PF00165; match to protein family HMM PF07883 YP_002114373.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_002114374.1 identified by match to protein family HMM PF01144 YP_002114375.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis YP_002114376.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate YP_002114377.1 identified by match to protein family HMM PF07690 YP_002114378.1 identified by match to protein family HMM PF07690 YP_002114379.1 identified by match to protein family HMM PF08965 YP_002114380.1 'YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function' YP_002114381.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913 YP_002114382.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_002114383.1 identified by match to protein family HMM PF00375 YP_002114384.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein YP_002114385.1 with SufCD activates cysteine desulfurase SufS YP_002114386.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_002114387.1 with SufBC activates cysteine desulfurase SufS YP_002114388.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine YP_002114389.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_002114390.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734 YP_002114391.1 identified by match to protein family HMM PF04728 YP_002114392.1 identified by match to protein family HMM PF04728 YP_002114393.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002114394.1 identified by match to protein family HMM PF00324 YP_002114395.1 identified by match to protein family HMM PF00561; match to protein family HMM TIGR01250 YP_002114396.1 identified by match to protein family HMM PF07090 YP_002114397.1 identified by match to protein family HMM PF00294; match to protein family HMM PF08220; match to protein family HMM PF08543 YP_002114398.1 identified by match to protein family HMM PF01568; match to protein family HMM PF04879 YP_002114399.1 identified by match to protein family HMM PF03916 YP_002114400.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409 YP_002114401.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002114402.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281 YP_002114404.1 identified by match to protein family HMM PF04463; match to protein family HMM PF08349 YP_002114405.1 identified by match to protein family HMM PF00376 YP_002114406.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196 YP_002114407.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002114408.1 identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02516 YP_002114409.1 identified by match to protein family HMM TIGR02500 YP_002114410.1 identified by match to protein family HMM TIGR02501 YP_002114411.1 identified by match to protein family HMM PF03433 YP_002114412.1 identified by match to protein family HMM PF07719; match to protein family HMM PF07720; match to protein family HMM TIGR02552 YP_002114413.1 identified by match to protein family HMM PF04888 YP_002114416.1 identified by match to protein family HMM TIGR02552 YP_002114419.1 identified by match to protein family HMM PF09392; match to protein family HMM TIGR02105 YP_002114420.2 identified by match to protein family HMM TIGR02498 YP_002114421.1 identified by match to protein family HMM PF09525; match to protein family HMM TIGR02497 YP_002114422.1 identified by match to protein family HMM PF01514; match to protein family HMM TIGR02544 YP_002114424.1 identified by match to protein family HMM TIGR02499 YP_002114425.1 identified by match to protein family HMM PF07018; match to protein family HMM TIGR02511 YP_002114427.1 with SsaC forms part of a protein export system across the inner and outer cell membranes; part of the Salmonella pathogenicity island 2; part of the type III secretion system YP_002114428.1 identified by match to protein family HMM PF00006; match to protein family HMM TIGR01026; match to protein family HMM TIGR02546 YP_002114431.1 identified by match to protein family HMM PF01052; match to protein family HMM TIGR02551 YP_002114432.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response YP_002114434.1 identified by match to protein family HMM PF01311; match to protein family HMM TIGR01401 YP_002114435.1 'member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli' YP_002114436.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_002114437.1 'catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine' YP_002114438.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_002114439.1 uncharacterized member of the major facilitator superfamily (MFS) YP_002114440.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002114441.1 'binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers' YP_002114442.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals YP_002114443.1 identified by match to protein family HMM PF00877 YP_002114444.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR00365 YP_002114445.1 identified by glimmer YP_002114446.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_002114447.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione YP_002114448.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide YP_002114449.1 identified by match to protein family HMM PF00440 YP_002114451.1 identified by match to protein family HMM PF00248 YP_002114452.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water YP_002114453.1 identified by match to protein family HMM PF04632 YP_002114454.1 identified by match to protein family HMM PF00529 YP_002114455.1 identified by match to protein family HMM PF07869 YP_002114456.1 Transcription regulator that can both activate or repress expression YP_002114457.1 identified by match to protein family HMM PF05433 YP_002114458.1 'catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling' YP_002114459.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme YP_002114460.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_002114461.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_002114462.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_002114463.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_002114464.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation YP_002114465.1 identified by glimmer YP_002114466.1 'DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines' YP_002114467.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_002114468.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_002114469.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_002114470.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_002114471.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_002114472.1 identified by match to protein family HMM PF02508; match to protein family HMM TIGR01943 YP_002114474.1 'YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes' YP_002114475.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002114476.1 catalyzes the formation of inosine from adenosine YP_002114477.1 identified by match to protein family HMM PF00155 YP_002114478.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site YP_002114479.1 regulates malXY which are involved in maltose-glucose transport YP_002114480.1 identified by match to protein family HMM PF06097 YP_002114481.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218 YP_002114482.1 identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_002114483.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_002114484.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_002114485.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002114486.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969 YP_002114487.1 identified by match to protein family HMM PF00267 YP_002114489.1 response regulator in two-component regulatory system with RstB YP_002114490.1 identified by match to protein family HMM PF06942 YP_002114491.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905 YP_002114492.1 identified by match to protein family HMM PF07338 YP_002114493.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_002114494.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_002114495.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes YP_002114497.1 'with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS' YP_002114498.1 'with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS' YP_002114499.1 identified by match to protein family HMM PF00089 YP_002114500.1 identified by glimmer YP_002114501.1 required for growth and survival under moderately acid conditions YP_002114502.1 identified by match to protein family HMM PF07690 YP_002114503.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002114504.1 identified by match to protein family HMM PF00480 YP_002114505.1 'DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium' YP_002114506.1 identified by match to protein family HMM PF00654 YP_002114507.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00571; match to protein family HMM TIGR01186 YP_002114508.1 identified by match to protein family HMM PF00528 YP_002114509.1 identified by match to protein family HMM PF04069 YP_002114510.1 identified by match to protein family HMM PF00528 YP_002114511.1 'binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane' YP_002114512.1 identified by match to protein family HMM PF04976 YP_002114513.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_002114514.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_002114515.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_002114516.1 identified by match to protein family HMM PF06649 YP_002114517.1 identified by match to protein family HMM PF06788 YP_002114518.1 identified by match to protein family HMM PF00583 YP_002114519.1 identified by match to protein family HMM PF06932 YP_002114520.1 identified by match to protein family HMM PF02694 YP_002114521.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002114522.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002114523.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_002114525.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_002114526.1 identified by match to protein family HMM TIGR03318 YP_002114527.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002114528.1 'NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine' YP_002114529.1 identified by match to protein family HMM PF01432 YP_002114531.1 identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199 YP_002114532.1 identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156 YP_002114533.1 identified by glimmer YP_002114535.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters YP_002114536.1 identified by match to protein family HMM PF00892 YP_002114538.1 'transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF' YP_002114539.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes YP_002114540.1 'protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function' YP_002114541.1 identified by match to protein family HMM PF07690 YP_002114542.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002114543.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase YP_002114544.1 catalyzes the formation of glutamate from glutamine YP_002114547.1 identified by match to protein family HMM PF00267 YP_002114548.1 identified by match to protein family HMM PF01155; match to protein family HMM TIGR00100 YP_002114550.1 identified by match to protein family HMM PF00301; match to protein family HMM PF04809 YP_002114551.1 identified by match to protein family HMM PF07449 YP_002114552.1 identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074 YP_002114553.1 identified by match to protein family HMM PF01750; match to protein family HMM TIGR00072; match to protein family HMM TIGR00140 YP_002114554.1 identified by match to protein family HMM PF01292; match to protein family HMM TIGR02125 YP_002114555.1 identified by match to protein family HMM PF00374 YP_002114556.1 identified by match to protein family HMM PF01058; match to protein family HMM PF08425; match to protein family HMM TIGR00391 YP_002114557.1 identified by match to protein family HMM PF02275 YP_002114558.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002114559.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002114560.1 identified by match to protein family HMM PF07690 YP_002114562.1 identified by match to protein family HMM PF07690 YP_002114563.1 identified by match to protein family HMM PF01494 YP_002114564.1 identified by match to protein family HMM PF01047 YP_002114565.1 identified by glimmer YP_002114568.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385 YP_002114571.1 identified by match to protein family HMM PF07377 YP_002114572.1 identified by match to protein family HMM PF08357 YP_002114573.1 identified by glimmer YP_002114575.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002114576.1 identified by match to protein family HMM PF03060 YP_002114577.1 identified by glimmer YP_002114578.1 identified by match to protein family HMM PF00532 YP_002114579.1 identified by match to protein family HMM PF03553; match to protein family HMM TIGR00931 YP_002114580.1 identified by match to protein family HMM PF00155 YP_002114581.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02100 YP_002114582.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02401 YP_002114583.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402 YP_002114584.1 identified by match to protein family HMM PF06884 YP_002114587.1 Acts by forming a pore-like structure upon contact with mammalian cells YP_002114588.1 identified by match to protein family HMM PF02566; match to protein family HMM TIGR03562 YP_002114590.1 identified by glimmer YP_002114591.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_002114592.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_002114593.1 'nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase' YP_002114594.1 identified by match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582 YP_002114595.1 identified by match to protein family HMM PF00892 YP_002114596.1 identified by match to protein family HMM PF00267 YP_002114597.1 identified by match to protein family HMM PF04828 YP_002114598.1 identified by match to protein family HMM PF07690 YP_002114599.1 identified by match to protein family HMM PF00440 YP_002114600.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00886 YP_002114601.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580 YP_002114602.1 identified by match to protein family HMM TIGR01660 YP_002114603.1 identified by match to protein family HMM PF02613; match to protein family HMM TIGR00684 YP_002114604.1 identified by match to protein family HMM PF02665; match to protein family HMM TIGR00351 YP_002114605.1 identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654 YP_002114606.1 identified by match to protein family HMM PF00797 YP_002114607.1 identified by glimmer YP_002114609.1 identified by match to protein family HMM PF00324 YP_002114610.1 identified by match to protein family HMM PF06004 YP_002114612.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715 YP_002114613.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002114614.1 identified by match to protein family HMM PF00107 YP_002114615.1 identified by match to protein family HMM PF00583 YP_002114616.1 identified by match to protein family HMM PF04657 YP_002114619.1 identified by match to protein family HMM PF07520 YP_002114622.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_002114623.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002114624.1 identified by match to protein family HMM PF01427 YP_002114626.1 translocated by the type III secretion system SPI-2; localizes to Sifs in infected cells and specifically to Salmonella-containing vacuoles YP_002114628.1 identified by match to protein family HMM PF01136 YP_002114629.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002114630.1 identified by match to protein family HMM PF00860; match to protein family HMM PF03594; match to protein family HMM TIGR00843 YP_002114632.1 with TehA confers resistance to tellurite YP_002114633.1 identified by match to protein family HMM PF03595; match to protein family HMM TIGR00816 YP_002114635.1 identified by match to protein family HMM PF00583 YP_002114636.1 identified by match to protein family HMM PF05343 YP_002114637.1 identified by match to protein family HMM PF02302 YP_002114638.1 identified by match to protein family HMM PF03611; match to protein family HMM TIGR00827 YP_002114639.1 identified by match to protein family HMM PF03437; match to protein family HMM TIGR00259 YP_002114640.1 identified by match to protein family HMM PF00359 YP_002114641.1 identified by match to protein family HMM PF00834 YP_002114642.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002114643.1 identified by match to protein family HMM PF00583 YP_002114644.1 identified by match to protein family HMM PF01070; match to protein family HMM PF01180 YP_002114645.1 identified by match to protein family HMM PF04264 YP_002114647.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_002114648.1 identified by match to protein family HMM PF00135 YP_002114649.1 identified by match to protein family HMM PF07063 YP_002114650.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002114651.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_002114652.1 identified by glimmer YP_002114653.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818 YP_002114654.1 identified by match to protein family HMM PF02583 YP_002114655.1 identified by glimmer YP_002114658.1 identified by match to protein family HMM PF06961 YP_002114659.1 identified by match to protein family HMM PF00497 YP_002114660.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002114661.1 identified by match to protein family HMM PF00005 YP_002114662.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002114664.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002114665.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm YP_002114666.1 identified by match to protein family HMM PF02698 YP_002114667.1 'involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain' YP_002114668.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_002114669.1 identified by match to protein family HMM PF04828 YP_002114670.1 identified by match to protein family HMM PF07027 YP_002114673.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_002114674.1 identified by match to protein family HMM PF03724 YP_002114676.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176 YP_002114677.1 identified by glimmer YP_002114678.1 identified by match to protein family HMM PF00582 YP_002114679.1 identified by match to protein family HMM PF00893 YP_002114682.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_002114683.1 'exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA' YP_002114684.1 identified by match to protein family HMM PF01544 YP_002114685.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002114687.1 identified by match to protein family HMM PF01713 YP_002114688.1 identified by match to protein family HMM PF01035; match to protein family HMM PF02870; match to protein family HMM TIGR00589 YP_002114689.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_002114690.1 with UspC and UspD is involved in resistance to UV irradiation YP_002114692.1 identified by match to protein family HMM PF00924 YP_002114693.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002114694.1 identified by match to protein family HMM PF03483 YP_002114700.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_002114702.1 identified by match to protein family HMM PF06004 YP_002114703.1 identified by match to protein family HMM PF00440 YP_002114704.1 identified by match to protein family HMM PF00106 YP_002114705.1 identified by match to protein family HMM PF00248 YP_002114706.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002114707.1 identified by match to protein family HMM PF05368 YP_002114708.1 identified by match to protein family HMM PF00496 YP_002114709.1 identified by match to protein family HMM PF00246 YP_002114710.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002114711.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_002114712.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_002114713.1 identified by match to protein family HMM PF05128; match to protein family HMM TIGR01620 YP_002114714.1 identified by match to protein family HMM PF04317 YP_002114715.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide YP_002114716.1 identified by match to protein family HMM PF09584; match to protein family HMM TIGR02979 YP_002114717.1 'with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock' YP_002114718.1 'acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding' YP_002114719.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_002114720.1 'transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor' YP_002114721.1 identified by match to protein family HMM PF00496 YP_002114722.1 identified by match to protein family HMM PF00528 YP_002114724.1 identified by match to protein family HMM PF00528 YP_002114725.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002114726.1 identified by match to protein family HMM PF00005 YP_002114729.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_002114730.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_002114731.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP YP_002114733.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002114735.1 involved in start site selection during the initiation of translation YP_002114736.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_002114737.1 identified by match to protein family HMM PF07719 YP_002114738.1 identified by match to protein family HMM PF06305 YP_002114739.1 identified by match to protein family HMM PF01569 YP_002114740.2 'catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate' YP_002114741.1 Catalyzes the conversion of citrate to isocitrate YP_002114744.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_002114745.1 identified by glimmer YP_002114746.1 'catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity' YP_002114748.1 SohB; periplasmic protein; member of the peptidase S49 family YP_002114749.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002114750.1 'catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide' YP_002114751.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_002114752.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057 YP_002114753.1 identified by match to protein family HMM PF02811 YP_002114754.1 'with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine' YP_002114755.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis YP_002114756.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_002114757.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_002114758.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_002114760.1 identified by match to protein family HMM PF05974 YP_002114761.1 identified by match to protein family HMM PF05974 YP_002114762.1 identified by match to protein family HMM PF05067 YP_002114763.1 receptor for colicin S4 YP_002114764.1 identified by glimmer YP_002114765.1 identified by match to protein family HMM PF03692 YP_002114766.1 identified by match to protein family HMM PF06790 YP_002114767.1 Involved in cell division; probably involved in intracellular septation YP_002114768.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins YP_002114769.1 'membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins' YP_002114770.1 'unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity' YP_002114772.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_002114773.1 identified by match to protein family HMM PF00520; match to protein family HMM PF07885 YP_002114774.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002114775.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002114776.1 identified by match to protein family HMM PF00528 YP_002114777.1 identified by match to protein family HMM PF00528 YP_002114778.1 identified by match to protein family HMM PF00496 YP_002114779.1 identified by match to protein family HMM PF01914; match to protein family HMM TIGR00427 YP_002114780.1 identified by match to protein family HMM PF00171; match to protein family HMM PF00465 YP_002114781.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_002114782.1 identified by match to protein family HMM PF00816 YP_002114783.1 'together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose' YP_002114784.1 identified by match to protein family HMM PF00072 YP_002114785.1 identified by match to protein family HMM PF01734 YP_002114786.1 identified by match to protein family HMM PF02810 YP_002114787.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_002114789.1 identified by glimmer YP_002114790.1 identified by match to protein family HMM PF02665; match to protein family HMM TIGR00351 YP_002114791.1 identified by match to protein family HMM PF02613; match to protein family HMM TIGR00684 YP_002114792.1 identified by match to protein family HMM TIGR01660 YP_002114793.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580 YP_002114794.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00886 YP_002114796.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002114797.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase YP_002114799.1 identified by match to protein family HMM PF02635 YP_002114800.1 in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions YP_002114801.1 identified by match to protein family HMM PF01699; match to protein family HMM TIGR00846 YP_002114802.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_002114804.1 identified by match to protein family HMM PF04247 YP_002114805.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB YP_002114806.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_002114807.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_002114808.1 identified by glimmer YP_002114809.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_002114810.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_002114811.1 identified by glimmer YP_002114812.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_002114813.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_002114814.1 'YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function' YP_002114815.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_002114816.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_002114817.1 identified by glimmer YP_002114818.1 identified by glimmer YP_002114820.1 identified by glimmer YP_002114821.2 identified by match to protein family HMM PF01058; match to protein family HMM PF08425; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409 YP_002114822.1 involved in hydrogen cycling during fermentative growth YP_002114823.1 identified by match to protein family HMM PF01292; match to protein family HMM TIGR02125 YP_002114824.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1) YP_002114825.1 involved in processing hydrogenase proteins HyaA and HyaB YP_002114826.1 identified by match to protein family HMM PF04809 YP_002114827.1 identified by match to protein family HMM PF01654 YP_002114828.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_002114829.1 identified by match to protein family HMM PF00208; match to protein family HMM PF02812 YP_002114831.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell YP_002114832.1 identified by match to protein family HMM PF04226 YP_002114833.1 identified by match to protein family HMM PF07238; match to protein family HMM PF07317 YP_002114834.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine YP_002114835.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_002114836.1 'catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA' YP_002114837.1 catalyzes the oxidative deamination of D-amino acids YP_002114838.1 identified by match to protein family HMM PF04293 YP_002114839.1 Multifunctional regulator of fatty acid metabolism YP_002114840.1 involved in regulation of intracellular pH under alkaline conditions YP_002114841.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_002114842.1 identified by match to protein family HMM PF09313 YP_002114843.1 identified by match to protein family HMM PF08178 YP_002114845.1 identified by match to protein family HMM PF03692 YP_002114846.1 identified by match to protein family HMM PF01557 YP_002114847.2 identified by match to protein family HMM PF05166 YP_002114848.1 blocks the formation of polar Z-ring septums YP_002114849.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_002114850.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_002114851.1 identified by match to protein family HMM PF00570; match to protein family HMM PF01612; match to protein family HMM TIGR01388 YP_002114852.1 Activates fatty acids by binding to coenzyme A YP_002114854.1 identified by match to protein family HMM PF03843; match to protein family HMM TIGR00752 YP_002114855.1 identified by match to protein family HMM PF00814 YP_002114857.1 identified by match to protein family HMM PF01042 YP_002114858.1 identified by match to protein family HMM PF03701 YP_002114859.1 identified by match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553 YP_002114860.1 identified by match to protein family HMM PF00293 YP_002114861.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_002114862.1 identified by match to protein family HMM PF00563 YP_002114863.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741 YP_002114864.1 identified by match to protein family HMM PF03610; match to protein family HMM PF03830; match to protein family HMM TIGR00824; match to protein family HMM TIGR00854 YP_002114865.1 identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822 YP_002114866.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel YP_002114867.1 identified by match to protein family HMM PF06173 YP_002114868.1 identified by match to protein family HMM PF02659 YP_002114869.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_002114870.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002114871.1 identified by match to protein family HMM PF00313 YP_002114875.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_002114876.1 metalloprotease YP_002114877.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_002114878.1 affects solute and DNA transport through an unknown mechanism YP_002114879.2 identified by match to protein family HMM PF01590 YP_002114880.1 identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155 YP_002114881.1 identified by match to protein family HMM PF02470 YP_002114882.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_002114883.1 identified by match to protein family HMM PF07351 YP_002114884.1 identified by match to protein family HMM PF07358 YP_002114885.2 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins YP_002114888.2 identified by match to protein family HMM PF07487 YP_002114889.1 identified by glimmer YP_002114890.1 identified by match to protein family HMM PF07166 YP_002114892.1 identified by match to protein family HMM PF00583 YP_002114894.1 identified by glimmer YP_002114897.1 identified by glimmer YP_002114902.1 identified by match to protein family HMM PF02413; match to protein family HMM PF07484 YP_002114903.1 identified by match to protein family HMM PF07278 YP_002114907.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003 YP_002114909.1 identified by match to protein family HMM PF05425 YP_002114910.1 identified by match to protein family HMM PF04234 YP_002114911.1 identified by match to protein family HMM PF06440 YP_002114912.1 identified by match to protein family HMM PF00795 YP_002114913.1 3'-5' exonuclease activity on single or double-strand DNA YP_002114914.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues YP_002114915.1 identified by match to protein family HMM PF04391 YP_002114916.1 secreted protein; unknown function YP_002114917.1 identified by match to protein family HMM PF07130 YP_002114918.1 'non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis' YP_002114919.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_002114920.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_002114921.1 'catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate' YP_002114922.1 'Represses the expression of the zwf, eda, glp and gap' YP_002114923.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002114924.1 'Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA' YP_002114925.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551; match to protein family HMM PF04225; match to protein family HMM PF08525 YP_002114926.1 involved in transport of zinc(II) with ZnuA and C YP_002114927.1 involved in transport of zinc(II) with ZnuA and C YP_002114928.1 involved in transport of zinc(II) with ZnuA and C YP_002114929.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_002114930.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_002114932.1 identified by match to protein family HMM PF06520 YP_002114933.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_002114934.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_002114935.1 converts dATP to dAMP and pyrophosphate YP_002114936.1 'catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes' YP_002114937.1 identified by match to protein family HMM PF00857 YP_002114938.1 identified by match to protein family HMM PF01904 YP_002114940.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00740 YP_002114941.1 identified by match to protein family HMM PF08003; match to protein family HMM PF08241; match to protein family HMM TIGR00452 YP_002114942.1 identified by match to protein family HMM PF03932 YP_002114943.1 identified by match to protein family HMM PF06185 YP_002114945.1 'catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase' YP_002114946.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM TIGR03423 YP_002114947.1 identified by match to protein family HMM PF07470 YP_002114948.1 identified by match to protein family HMM PF06366 YP_002114949.1 membrane protein involved in the flagellar export apparatus YP_002114950.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_002114951.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_002114952.1 'chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble' YP_002114953.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_002114954.1 methylates the MCP YP_002114955.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_002114956.1 identified by glimmer YP_002114957.1 identified by match to protein family HMM PF01584 YP_002114958.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_002114959.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_002114960.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_002114961.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_002114962.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_002114963.1 'ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress' YP_002114964.1 identified by match to protein family HMM PF00982; match to protein family HMM TIGR02400 YP_002114965.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature YP_002114966.1 identified by match to protein family HMM PF01965 YP_002114967.1 identified by glimmer YP_002114968.1 identified by match to protein family HMM PF00210 YP_002114969.1 identified by match to protein family HMM PF02502 YP_002114971.1 cytoplasmic iron storage protein YP_002114973.1 identified by match to protein family HMM PF01490; match to protein family HMM PF03222; match to protein family HMM TIGR00837 YP_002114974.1 identified by match to protein family HMM PF02810; match to protein family HMM TIGR02292 YP_002114976.1 identified by match to protein family HMM PF00877 YP_002114977.1 identified by glimmer YP_002114978.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560 YP_002114979.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_002114980.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_002114983.1 regulates genes involved in cell division YP_002114984.1 identified by match to protein family HMM PF00005 YP_002114985.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002114986.1 catalyzes the formation of pyruvate from D-cysteine YP_002114987.1 identified by match to protein family HMM PF00497 YP_002114988.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_002114990.1 'structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes' YP_002114992.1 identified by glimmer YP_002114993.1 involved in flagellin assembly YP_002114994.1 flagellin specific chaperone YP_002114995.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family YP_002114996.1 'converts 1,4-alpha-D-glucans to maltodextrin' YP_002114998.2 identified by match to protein family HMM PF04143 YP_002114999.1 identified by match to protein family HMM PF01206 YP_002115001.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_002115003.1 'the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod' YP_002115004.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002115005.1 binds to and inhibits the function of flagella specific ATPase FliI YP_002115006.1 involved in type III protein export during flagellum assembly YP_002115007.1 rod/hook and filament chaperone YP_002115008.1 identified by match to protein family HMM PF02120 YP_002115009.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_002115010.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_002115011.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002115012.1 'with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus' YP_002115013.1 'FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus' YP_002115014.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_002115015.1 'FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus' YP_002115016.1 identified by glimmer YP_002115017.1 identified by match to protein family HMM PF00196 YP_002115020.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate YP_002115021.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002115023.1 identified by match to protein family HMM PF05661 YP_002115024.1 identified by match to protein family HMM PF00892 YP_002115025.1 identified by match to protein family HMM PF03852; match to protein family HMM TIGR00632 YP_002115026.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_002115027.1 identified by match to protein family HMM PF01966 YP_002115029.1 identified by glimmer YP_002115030.1 identified by match to protein family HMM PF00267 YP_002115031.1 identified by glimmer YP_002115032.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_002115033.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_002115035.1 identified by match to protein family HMM PF06167 YP_002115036.1 identified by glimmer YP_002115037.1 identified by glimmer YP_002115038.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_002115040.1 identified by match to protein family HMM PF07377 YP_002115041.1 identified by glimmer YP_002115042.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002115043.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_002115044.1 identified by match to protein family HMM PF00892 YP_002115045.1 identified by match to protein family HMM PF00501 YP_002115046.1 identified by match to protein family HMM PF01276 YP_002115047.1 identified by glimmer YP_002115048.1 identified by match to protein family HMM PF03734 YP_002115049.1 'catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole' YP_002115050.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_002115051.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP YP_002115052.1 'catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation' YP_002115053.1 with CbiNQ forms the ABC transporter for cobalt import YP_002115054.1 identified by match to protein family HMM PF02361; match to protein family HMM TIGR02454 YP_002115055.1 periplasmic cobalt binding component of the cobalt transport system YP_002115056.1 catalyzes the ATP-dependent transport of cobalt YP_002115057.1 catalyzes the formation of precorrin-3A from precorrin-2 YP_002115058.1 identified by match to protein family HMM PF06180 YP_002115059.1 'CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6' YP_002115060.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR01466 YP_002115061.1 catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3 YP_002115062.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465 YP_002115063.1 catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W; decarboxylating YP_002115064.1 catalyzes the methylation of C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W-a YP_002115065.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A YP_002115066.1 catalyzes the interconversion of cobalt-precorrin-8X and cobyrinic acid in the anaerobic biosynthesis of cobalamin YP_002115067.1 CobD; CbiB in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group YP_002115068.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_002115069.1 identified by match to protein family HMM PF00165 YP_002115070.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861 YP_002115071.1 identified by match to protein family HMM PF00936 YP_002115072.1 identified by match to protein family HMM PF00936 YP_002115073.1 identified by match to protein family HMM PF02286 YP_002115074.1 identified by match to protein family HMM PF02288 YP_002115075.1 identified by match to protein family HMM PF02287 YP_002115076.1 identified by match to protein family HMM PF08841 YP_002115078.1 identified by match to protein family HMM PF00936 YP_002115079.1 identified by match to protein family HMM PF00936 YP_002115080.1 identified by match to protein family HMM PF06130 YP_002115082.1 identified by match to protein family HMM PF03319 YP_002115083.1 identified by match to protein family HMM PF01923; match to protein family HMM PF03928; match to protein family HMM TIGR00636 YP_002115084.1 identified by match to protein family HMM PF00171 YP_002115085.1 identified by match to protein family HMM PF00465 YP_002115086.1 identified by match to protein family HMM PF01512 YP_002115087.1 identified by match to protein family HMM PF00936 YP_002115088.1 identified by match to protein family HMM PF00936 YP_002115089.1 identified by match to protein family HMM TIGR02528 YP_002115090.1 'involved in coenzyme B(12)-dependent 1, 2-propanediol degradation; important for the synthesis of propionyl coenzyme A during growth on 1,2-propanediol' YP_002115091.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544 YP_002115092.1 identified by match to protein family HMM PF04363 YP_002115094.1 identified by match to protein family HMM PF06445 YP_002115095.1 'removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains' YP_002115096.1 identified by match to protein family HMM PF01292 YP_002115097.1 identified by match to protein family HMM PF00037 YP_002115098.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409 YP_002115100.1 identified by glimmer YP_002115101.1 identified by glimmer YP_002115102.1 identified by glimmer YP_002115105.1 identified by match to protein family HMM PF01757 YP_002115107.1 identified by match to protein family HMM PF02413 YP_002115110.1 identified by match to protein family HMM PF04865 YP_002115111.1 identified by match to protein family HMM PF07409 YP_002115112.1 identified by match to protein family HMM PF06890; match to protein family HMM TIGR01644 YP_002115113.1 identified by match to protein family HMM PF06893 YP_002115114.1 identified by match to protein family HMM PF07157 YP_002115115.1 identified by match to protein family HMM TIGR01760 YP_002115118.1 identified by match to protein family HMM PF06274 YP_002115122.1 identified by match to protein family HMM TIGR01563 YP_002115125.1 identified by match to protein family HMM PF05065; match to protein family HMM TIGR01554 YP_002115126.1 identified by match to protein family HMM PF04586; match to protein family HMM TIGR01543 YP_002115127.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537 YP_002115129.1 identified by match to protein family HMM PF03354 YP_002115130.1 identified by match to protein family HMM PF05119; match to protein family HMM TIGR01558 YP_002115132.1 identified by glimmer YP_002115134.1 identified by match to protein family HMM PF00182 YP_002115135.1 identified by match to protein family HMM PF05106; match to protein family HMM TIGR01594 YP_002115136.1 identified by match to protein family HMM PF06323 YP_002115137.1 identified by match to protein family HMM PF05766 YP_002115139.1 identified by match to protein family HMM PF07105 YP_002115140.1 identified by match to protein family HMM PF06183 YP_002115142.1 identified by match to protein family HMM PF06163 YP_002115143.1 identified by match to protein family HMM PF01695 YP_002115144.1 identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610 YP_002115149.1 identified by match to protein family HMM PF06630 YP_002115150.1 identified by match to protein family HMM PF03837 YP_002115152.1 identified by match to protein family HMM PF00589 YP_002115153.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_002115154.1 identified by match to protein family HMM PF00324 YP_002115155.1 identified by glimmer YP_002115156.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002115157.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370 YP_002115158.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_002115159.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_002115160.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_002115161.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_002115162.1 'with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide' YP_002115163.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_002115164.1 'catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase' YP_002115165.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_002115166.1 identified by match to protein family HMM PF02706 YP_002115167.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_002115168.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_002115169.1 identified by match to protein family HMM PF02397; match to protein family HMM TIGR03022; match to protein family HMM TIGR03025 YP_002115170.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880 YP_002115171.1 identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479 YP_002115172.1 identified by match to protein family HMM PF00535 YP_002115173.1 identified by match to protein family HMM PF00534 YP_002115176.1 identified by match to protein family HMM PF00535 YP_002115177.1 identified by match to protein family HMM PF01943 YP_002115178.1 identified by match to protein family HMM PF01370 YP_002115179.1 identified by match to protein family HMM PF01041 YP_002115180.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993; match to protein family HMM TIGR02622 YP_002115181.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR02623 YP_002115182.1 'catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose' YP_002115183.1 identified by match to protein family HMM PF00908; match to protein family HMM TIGR01221 YP_002115184.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207 YP_002115185.1 'with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose' YP_002115186.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose YP_002115187.1 'together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose' YP_002115188.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid YP_002115189.1 identified by match to protein family HMM PF00534 YP_002115190.1 identified by match to protein family HMM PF04230 YP_002115191.1 identified by match to protein family HMM PF01943 YP_002115192.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier UDP phosphate in the biosynthesis of colanic acid YP_002115193.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880 YP_002115194.1 identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479 YP_002115195.1 identified by match to protein family HMM PF00534 YP_002115196.1 identified by match to protein family HMM PF00293 YP_002115197.1 identified by match to protein family HMM PF01370 YP_002115198.1 identified by match to protein family HMM PF01370; match to protein family HMM TIGR01472 YP_002115199.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit) YP_002115200.1 identified by match to protein family HMM PF00535 YP_002115201.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance YP_002115203.1 'acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium' YP_002115204.2 identified by match to protein family HMM PF00535 YP_002115205.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) YP_002115206.1 'Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis' YP_002115207.2 identified by match to protein family HMM PF02563 YP_002115208.1 identified by glimmer YP_002115209.1 'YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs' YP_002115210.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_002115211.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_002115213.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF05231; match to protein family HMM PF08447; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_002115214.1 'inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine' YP_002115216.1 identified by glimmer YP_002115217.1 'Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate' YP_002115218.1 'Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate' YP_002115219.1 'Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate' YP_002115220.1 identified by match to protein family HMM PF07690 YP_002115221.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002115222.1 'response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport' YP_002115226.1 identified by match to protein family HMM PF01136 YP_002115229.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_002115230.1 identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889 YP_002115231.1 identified by match to protein family HMM PF03747 YP_002115232.1 identified by match to protein family HMM PF00294 YP_002115233.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002115234.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_002115235.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_002115236.1 identified by glimmer YP_002115238.1 identified by match to protein family HMM PF00419 YP_002115239.1 identified by match to protein family HMM PF00577 YP_002115240.1 identified by match to protein family HMM PF00345 YP_002115241.1 identified by match to protein family HMM PF00419 YP_002115244.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002115245.1 identified by match to protein family HMM PF06998 YP_002115246.1 identified by match to protein family HMM PF06998 YP_002115247.1 identified by match to protein family HMM PF07308 YP_002115248.1 unknown function; when overproduced it confers drug-resistance YP_002115249.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694 YP_002115250.1 identified by match to protein family HMM PF00376 YP_002115251.1 identified by match to protein family HMM PF00528 YP_002115252.1 identified by match to protein family HMM PF00005 YP_002115253.1 identified by match to protein family HMM PF00528 YP_002115254.1 identified by match to protein family HMM PF04069 YP_002115255.1 identified by match to protein family HMM PF00933; match to protein family HMM PF01915 YP_002115256.1 'component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent' YP_002115257.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_002115258.1 identified by match to protein family HMM PF06930 YP_002115259.1 identified by match to protein family HMM PF09335 YP_002115260.1 identified by match to protein family HMM PF00106 YP_002115261.1 'may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride' YP_002115264.1 identified by match to protein family HMM PF01207 YP_002115265.1 catalyzes the formation of catechol from salicylate YP_002115266.1 identified by match to protein family HMM PF02798; match to protein family HMM TIGR01262 YP_002115267.1 identified by match to protein family HMM PF01557 YP_002115268.1 identified by match to protein family HMM PF07883; match to protein family HMM TIGR02272 YP_002115269.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002115270.1 identified by match to protein family HMM PF03788 YP_002115271.1 identified by match to protein family HMM PF04172; match to protein family HMM TIGR00659 YP_002115272.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_002115273.1 identified by match to protein family HMM PF02698 YP_002115275.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_002115276.1 'catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines' YP_002115277.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_002115278.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_002115279.1 identified by match to protein family HMM PF00532 YP_002115280.1 negative regulator of the mglBAC operon for galactose utilization YP_002115281.1 identified by match to protein family HMM PF04171; match to protein family HMM PF04235 YP_002115282.1 'involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer' YP_002115283.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821 YP_002115284.1 identified by match to protein family HMM PF01381 YP_002115285.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_002115286.1 identified by match to protein family HMM PF00702; match to protein family HMM PF06888; match to protein family HMM PF08282; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488 YP_002115287.1 identified by match to protein family HMM PF07690 YP_002115288.1 'Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein' YP_002115289.1 identified by match to protein family HMM PF00324 YP_002115290.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002115291.1 identified by match to protein family HMM PF03601; match to protein family HMM TIGR00698 YP_002115292.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_002115293.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002115294.1 'converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers' YP_002115295.1 'phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr' YP_002115296.1 identified by glimmer YP_002115297.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00899 YP_002115301.1 'Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein' YP_002115302.1 identified by match to protein family HMM PF02492 YP_002115303.1 identified by match to protein family HMM PF01569 YP_002115304.1 'by similarity, Spr seems to have peptidase activity; involved in thermoresistance' YP_002115305.1 identified by match to protein family HMM PF00563 YP_002115306.1 identified by match to protein family HMM PF00496 YP_002115307.1 identified by match to protein family HMM PF00528 YP_002115308.1 identified by match to protein family HMM PF00528 YP_002115309.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352 YP_002115311.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_002115312.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_002115313.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851 YP_002115314.1 'the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response' YP_002115315.1 identified by match to protein family HMM PF04245 YP_002115316.1 identified by match to protein family HMM PF07208 YP_002115317.1 identified by match to protein family HMM PF00884 YP_002115319.1 identified by match to protein family HMM PF09411 YP_002115320.1 identified by glimmer YP_002115321.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes YP_002115322.1 identified by match to protein family HMM PF03918 YP_002115323.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR00385 YP_002115324.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR00353 YP_002115325.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_002115326.1 identified by match to protein family HMM PF04995; match to protein family HMM TIGR03141 YP_002115327.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR01191 YP_002115328.1 identified by match to protein family HMM PF03379; match to protein family HMM TIGR01190 YP_002115329.1 ATP-binding protein; required for proper cytochrome c maturation YP_002115330.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone YP_002115331.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA YP_002115332.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_002115333.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_002115334.1 Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA. YP_002115335.1 'serine protease inhibitor, inhibits trypsin and other proteases' YP_002115336.1 efflux pump for the antibacterial peptide microcin J25 YP_002115337.1 identified by match to protein family HMM PF03171 YP_002115338.1 identified by match to protein family HMM PF00165; match to protein family HMM PF01035; match to protein family HMM PF02805; match to protein family HMM PF02870; match to protein family HMM TIGR00589 YP_002115339.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway YP_002115340.1 allows for ions and hydrophilic solutes to cross the outer membrane YP_002115341.1 identified by match to protein family HMM PF01627; match to protein family HMM PF02518 YP_002115342.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_002115343.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF09456 YP_002115344.1 negatively supercoils closed circular double-stranded DNA YP_002115345.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002115346.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002115347.1 Involved in ubiquinone biosynthesis YP_002115348.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002115349.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_002115350.1 'plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases' YP_002115351.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002115352.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic YP_002115353.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_002115354.1 'anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor' YP_002115355.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_002115356.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_002115357.1 'similar to ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system' YP_002115359.1 identified by match to protein family HMM PF03328 YP_002115360.1 identified by match to protein family HMM PF07690 YP_002115361.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002115362.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_002115363.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR00200 YP_002115364.1 identified by match to protein family HMM PF07437 YP_002115365.1 identified by match to protein family HMM PF00293 YP_002115366.1 identified by match to protein family HMM PF00300 YP_002115367.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_002115368.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to UDP phosphate YP_002115369.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_002115370.1 identified by match to protein family HMM PF01522 YP_002115371.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_002115372.1 identified by match to protein family HMM PF00893 YP_002115375.1 identified by match to protein family HMM PF00501; match to protein family HMM TIGR01923 YP_002115376.1 'catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate' YP_002115377.1 'catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA' YP_002115378.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_002115379.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_002115380.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543 YP_002115381.1 identified by match to protein family HMM PF05957 YP_002115382.1 identified by match to protein family HMM PF00583 YP_002115383.2 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_002115384.1 identified by match to protein family HMM PF00072; match to protein family HMM PF01584 YP_002115385.1 Catalyzes the transfer of electrons from NADH to quinone YP_002115386.1 Catalyzes the transfer of electrons from NADH to quinone YP_002115387.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002115388.1 Catalyzes the transfer of electrons from NADH to quinone YP_002115389.1 Catalyzes the transfer of electrons from NADH to quinone YP_002115390.1 Catalyzes the transfer of electrons from NADH to quinone YP_002115391.1 Catalyzes the transfer of electrons from NADH to quinone YP_002115392.1 Catalyzes the transfer of electrons from NADH to quinone YP_002115393.1 'shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase' YP_002115394.1 Catalyzes the transfer of electrons from NADH to quinone YP_002115395.1 'NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms' YP_002115396.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_002115397.1 Catalyzes the transfer of electrons from NADH to quinone YP_002115399.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002115400.1 'broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor' YP_002115401.1 identified by match to protein family HMM PF01966 YP_002115402.1 identified by match to protein family HMM PF02080; match to protein family HMM PF03600; match to protein family HMM PF06808 YP_002115403.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549 YP_002115404.1 identified by match to protein family HMM PF03887 YP_002115405.1 identified by match to protein family HMM PF04217 YP_002115406.1 identified by glimmer YP_002115407.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_002115408.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_002115409.1 identified by match to protein family HMM PF03606 YP_002115410.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780 YP_002115411.1 identified by match to protein family HMM PF00456 YP_002115412.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002115413.1 identified by match to protein family HMM PF02302 YP_002115414.1 identified by match to protein family HMM PF00359 YP_002115415.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002115416.1 identified by match to protein family HMM PF00293 YP_002115417.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040 YP_002115418.1 identified by match to protein family HMM PF02798 YP_002115419.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_002115420.1 identified by match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM PF08338; match to protein family HMM TIGR01777 YP_002115421.1 identified by match to protein family HMM PF00005 YP_002115422.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002115423.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002115424.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_002115425.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_002115427.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_002115428.1 identified by match to protein family HMM PF00324 YP_002115429.1 identified by match to protein family HMM PF01168 YP_002115430.1 identified by match to protein family HMM PF00324 YP_002115431.1 identified by match to protein family HMM PF00278; match to protein family HMM PF02784 YP_002115432.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF07728; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002115433.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_002115434.1 membrane protein required for colicin V production YP_002115435.1 identified by match to protein family HMM PF05036 YP_002115436.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499 YP_002115437.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_002115438.1 identified by match to protein family HMM PF09335 YP_002115439.1 'mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability' YP_002115440.1 identified by match to protein family HMM PF01118; match to protein family HMM PF02774 YP_002115441.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_002115442.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_002115443.1 identified by match to protein family HMM PF07690 YP_002115447.1 identified by match to protein family HMM PF02517 YP_002115448.1 'FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP' YP_002115449.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_002115450.1 identified by match to protein family HMM PF08891 YP_002115451.1 identified by match to protein family HMM PF04315 YP_002115452.1 identified by match to protein family HMM PF01925 YP_002115453.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_002115454.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_002115455.1 identified by match to protein family HMM PF01713 YP_002115456.1 identified by match to protein family HMM TIGR00249 YP_002115457.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_002115458.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_002115459.1 identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743 YP_002115460.1 identified by match to protein family HMM PF03349 YP_002115461.1 identified by match to protein family HMM PF04333 YP_002115463.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA YP_002115464.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954 YP_002115465.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002115467.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00881 YP_002115469.1 identified by glimmer YP_002115470.1 identified by glimmer YP_002115471.1 identified by match to protein family HMM PF00155 YP_002115472.1 identified by glimmer YP_002115473.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_002115474.1 identified by match to protein family HMM PF00654 YP_002115475.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776 YP_002115476.1 identified by glimmer YP_002115477.1 identified by match to protein family HMM PF00248 YP_002115479.1 identified by match to protein family HMM PF01566; match to protein family HMM TIGR01197 YP_002115480.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_002115481.1 identified by match to protein family HMM PF00563; match to protein family HMM PF05231 YP_002115482.1 identified by match to protein family HMM PF07037 YP_002115483.1 identified by match to protein family HMM PF07037 YP_002115484.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_002115485.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002115486.1 identified by match to protein family HMM TIGR03510 YP_002115487.1 identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889 YP_002115488.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_002115489.1 identified by match to protein family HMM PF07135 YP_002115490.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002115491.1 identified by match to protein family HMM PF01758 YP_002115493.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_002115494.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_002115495.1 role in sulfur assimilation YP_002115496.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_002115498.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_002115499.1 'Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system' YP_002115500.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_002115502.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_002115503.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002115504.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_002115506.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_002115507.1 identified by glimmer YP_002115508.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR00968 YP_002115509.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import YP_002115510.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139 YP_002115511.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971 YP_002115512.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659 YP_002115513.1 identified by match to protein family HMM PF04261; match to protein family HMM TIGR01413 YP_002115514.1 identified by match to protein family HMM PF06572 YP_002115516.1 identified by match to protein family HMM PF00583 YP_002115517.1 identified by match to protein family HMM PF01520; match to protein family HMM TIGR01409 YP_002115518.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_002115519.1 activates the transcription of the ethanolamine utilization operon YP_002115520.1 identified by match to protein family HMM PF00936 YP_002115521.1 identified by match to protein family HMM PF00936 YP_002115522.1 catalyzes the formation of acetaldehyde from ethanolamine YP_002115523.1 identified by match to protein family HMM PF06751 YP_002115524.1 ethanolamine utilization protein EutA YP_002115525.1 identified by match to protein family HMM PF04346 YP_002115526.1 identified by match to protein family HMM PF00465 YP_002115527.1 identified by match to protein family HMM TIGR02529 YP_002115528.1 identified by match to protein family HMM PF00171 YP_002115529.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_002115530.1 identified by match to protein family HMM PF01923 YP_002115531.1 identified by match to protein family HMM PF05899; match to protein family HMM PF06249 YP_002115532.1 identified by match to protein family HMM TIGR02528 YP_002115533.1 identified by match to protein family HMM PF00936 YP_002115534.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_002115535.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874 YP_002115536.1 'catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase' YP_002115538.1 identified by match to protein family HMM PF06674 YP_002115539.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052 YP_002115540.1 identified by match to protein family HMM PF00144 YP_002115541.1 'unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic)' YP_002115542.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002115543.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_002115544.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617 YP_002115545.1 'dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.' YP_002115547.1 identified by match to protein family HMM PF00583; match to protein family HMM PF05127 YP_002115548.1 identified by match to protein family HMM PF04228 YP_002115549.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_002115550.1 identified by glimmer YP_002115551.1 identified by match to protein family HMM PF06804 YP_002115552.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_002115553.1 negative transcriptional regulator of the gcvTHP operon YP_002115554.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_002115555.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_002115556.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600 YP_002115557.1 identified by match to protein family HMM PF05651 YP_002115558.1 identified by glimmer YP_002115559.1 identified by match to protein family HMM PF01594 YP_002115560.1 identified by match to protein family HMM PF01435 YP_002115561.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR00014 YP_002115562.1 'controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP' YP_002115563.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_002115564.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_002115565.1 identified by glimmer YP_002115566.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_002115567.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_002115568.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_002115569.1 identified by match to protein family HMM PF02541 YP_002115570.1 identified by match to protein family HMM PF00563; match to protein family HMM PF05231 YP_002115573.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_002115574.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_002115575.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_002115576.1 identified by match to protein family HMM PF05688; match to protein family HMM PF05689 YP_002115578.1 identified by glimmer YP_002115580.1 identified by glimmer YP_002115581.1 identified by match to protein family HMM PF07191 YP_002115582.1 'with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis' YP_002115584.1 'catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG' YP_002115585.1 'catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis' YP_002115586.1 identified by match to protein family HMM PF01381 YP_002115587.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_002115588.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_002115589.1 identified by match to protein family HMM PF00037 YP_002115591.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_002115592.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_002115593.1 penicillin-insensitive transglycosylase/transpeptidase YP_002115594.1 identified by match to protein family HMM PF01835; match to protein family HMM PF07703 YP_002115595.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds YP_002115596.1 identified by glimmer YP_002115597.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_002115598.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_002115599.1 identified by match to protein family HMM PF04384; match to protein family HMM TIGR03412 YP_002115600.1 identified by match to protein family HMM PF00111; match to protein family HMM TIGR02007 YP_002115601.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_002115602.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_002115603.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein YP_002115604.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01999 YP_002115605.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_002115606.1 identified by glimmer YP_002115607.1 regulates the expression of the iscRSUA operon YP_002115608.1 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00050 YP_002115609.1 identified by match to protein family HMM PF00459 YP_002115611.1 identified by match to protein family HMM TIGR02910 YP_002115612.1 with AsrAC catalyzes the reduction of sulfite to hydrogen sulfide YP_002115613.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM TIGR02912 YP_002115614.1 identified by match to protein family HMM PF03824 YP_002115615.1 identified by match to protein family HMM PF06226 YP_002115616.1 identified by match to protein family HMM PF00874 YP_002115617.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_002115618.1 'catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate' YP_002115620.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_002115621.1 regulates the cadBA operon YP_002115622.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein YP_002115623.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_002115624.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_002115625.1 'indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA' YP_002115626.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728 YP_002115628.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_002115630.1 'YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function' YP_002115631.1 identified by match to protein family HMM PF00383 YP_002115632.1 identified by match to protein family HMM TIGR01545 YP_002115633.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378 YP_002115634.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_002115635.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_002115636.1 identified by match to protein family HMM PF02558; match to protein family HMM PF08546; match to protein family HMM TIGR00745 YP_002115637.1 identified by match to protein family HMM PF07690 YP_002115638.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002115639.1 identified by match to protein family HMM PF00037 YP_002115640.1 'Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids' YP_002115641.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_002115642.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_002115643.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_002115644.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_002115645.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_002115646.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_002115647.1 identified by glimmer YP_002115648.1 involved in the reduction of the SoxR iron-sulfur cluster YP_002115649.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_002115650.1 identified by match to protein family HMM PF03872; match to protein family HMM PF03873 YP_002115651.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_002115652.1 identified by glimmer YP_002115653.1 catalyzes the formation of oxaloacetate from L-aspartate YP_002115655.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_002115656.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002115657.1 identified by match to protein family HMM PF01810 YP_002115658.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_002115659.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_002115660.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032 YP_002115661.1 identified by match to protein family HMM PF00085; match to protein family HMM PF08534; match to protein family HMM TIGR01068 YP_002115662.1 identified by match to protein family HMM PF03942 YP_002115663.1 identified by match to protein family HMM PF00583; match to protein family HMM PF02629 YP_002115664.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_002115666.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_002115668.1 identified by glimmer YP_002115670.1 identified by glimmer YP_002115671.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346 YP_002115672.1 identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726 YP_002115673.1 'responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA' YP_002115674.1 'with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline' YP_002115675.1 associated with 30S ribosomal subunit; interferes with translation elongation YP_002115676.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_002115677.1 identified by match to protein family HMM PF08450 YP_002115678.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_002115679.1 'catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive' YP_002115680.1 identified by glimmer YP_002115682.2 identified by match to protein family HMM PF00672; match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002115683.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_002115684.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_002115685.1 Essential for efficient processing of 16S rRNA YP_002115686.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_002115687.1 identified by glimmer YP_002115688.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_002115689.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_002115691.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_002115692.1 catalyzes the phosphorylation of NAD to NADP YP_002115693.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634 YP_002115694.1 identified by match to protein family HMM PF04355 YP_002115695.1 identified by match to protein family HMM PF03658 YP_002115696.1 identified by match to protein family HMM PF03364 YP_002115697.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_002115698.1 identified by glimmer YP_002115699.1 identified by glimmer YP_002115700.1 identified by match to protein family HMM TIGR01965 YP_002115701.1 identified by match to protein family HMM PF02321; match to protein family HMM TIGR01844 YP_002115702.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM TIGR03375 YP_002115703.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01843 YP_002115704.1 identified by match to protein family HMM PF00589 YP_002115705.1 identified by glimmer YP_002115706.1 identified by glimmer YP_002115707.1 identified by glimmer YP_002115710.1 identified by match to protein family HMM PF03432 YP_002115715.1 identified by glimmer YP_002115717.1 identified by glimmer YP_002115719.1 identified by match to protein family HMM PF05930 YP_002115721.1 identified by match to protein family HMM PF00078 YP_002115724.1 'structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes' YP_002115725.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_002115727.1 identified by match to protein family HMM PF06722 YP_002115728.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002115729.1 identified by match to protein family HMM PF00756 YP_002115731.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_002115732.1 identified by match to protein family HMM PF00805 YP_002115733.1 identified by match to protein family HMM PF04393 YP_002115734.1 identified by glimmer YP_002115735.1 identified by match to protein family HMM PF07395 YP_002115737.1 identified by match to protein family HMM PF03824; match to protein family HMM TIGR00802 YP_002115738.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF08521 YP_002115739.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002115741.1 identified by match to protein family HMM PF03401 YP_002115743.1 identified by match to protein family HMM PF01970 YP_002115744.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate YP_002115745.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_002115746.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR01773 YP_002115747.1 regulator of gab gene expression YP_002115748.1 identified by match to protein family HMM PF01476; match to protein family HMM PF04972 YP_002115749.1 identified by match to protein family HMM PF01679 YP_002115750.1 identified by match to protein family HMM PF01022 YP_002115751.1 identified by match to protein family HMM PF00581 YP_002115753.1 identified by match to protein family HMM PF00816 YP_002115754.1 identified by glimmer YP_002115755.1 identified by match to protein family HMM PF06610 YP_002115756.1 identified by match to protein family HMM PF09400 YP_002115757.1 identified by match to protein family HMM PF05957 YP_002115758.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002115759.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778 YP_002115761.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194 YP_002115762.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_002115763.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002115764.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_002115765.1 with ProWX is involved in the high-affinity uptake of glycine betaine YP_002115766.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_002115767.1 'with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine' YP_002115768.1 identified by match to protein family HMM PF07690 YP_002115769.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_002115770.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR00998 YP_002115771.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002115774.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_002115775.1 involved in the first step of glutathione biosynthesis YP_002115777.2 'YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent' YP_002115778.1 affects carbohydrate metabolism; has regulatory role in many processes YP_002115779.1 'Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA' YP_002115780.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_002115781.1 'catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs' YP_002115782.1 identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199 YP_002115783.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_002115784.1 identified by match to protein family HMM PF03608; match to protein family HMM TIGR00821 YP_002115785.1 identified by match to protein family HMM PF03612; match to protein family HMM PF07663; match to protein family HMM TIGR00825 YP_002115786.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002115787.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate YP_002115788.1 regulator for glucitol utilization YP_002115789.1 regulates genes involved in glucitol utilization YP_002115790.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate YP_002115791.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_002115792.1 detoxifies nitric oxide using NADH YP_002115793.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_002115794.1 identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143 YP_002115795.1 involved in electron transport from formate to hydrogen YP_002115798.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE YP_002115799.1 identified by match to protein family HMM PF07450 YP_002115800.1 identified by match to protein family HMM PF01058 YP_002115801.1 'electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate' YP_002115802.1 identified by match to protein family HMM PF00329; match to protein family HMM PF00346 YP_002115803.1 identified by match to protein family HMM PF00146 YP_002115804.1 'catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3)' YP_002115805.1 identified by match to protein family HMM PF00037 YP_002115806.1 identified by glimmer YP_002115807.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon YP_002115808.1 plays a role in hydrogenase nickel cofactor insertion YP_002115809.1 GTP hydrolase involved in nickel liganding into hydrogenases YP_002115810.1 'HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase' YP_002115811.1 identified by match to protein family HMM PF01924; match to protein family HMM TIGR00075 YP_002115812.1 identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR02124 YP_002115813.1 identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728 YP_002115815.1 identified by match to protein family HMM PF01297 YP_002115816.1 identified by match to protein family HMM PF00005 YP_002115817.1 identified by match to protein family HMM PF00950; match to protein family HMM PF01032 YP_002115818.1 identified by match to protein family HMM PF00950 YP_002115819.1 identified by match to protein family HMM PF03421 YP_002115821.1 identified by match to protein family HMM PF00165 YP_002115823.1 identified by match to protein family HMM PF09482; match to protein family HMM TIGR02555 YP_002115824.1 identified by match to protein family HMM PF01514; match to protein family HMM TIGR02544 YP_002115826.1 identified by match to protein family HMM PF09392; match to protein family HMM TIGR02105 YP_002115827.2 identified by match to protein family HMM PF09480; match to protein family HMM TIGR02554 YP_002115828.1 identified by match to protein family HMM PF00165 YP_002115829.1 Activates the expression of invasion genes and activates the expression of prgHIJK which is part of the pathogenicity island 1 type III secretion system YP_002115830.1 identified by match to protein family HMM PF01464 YP_002115831.1 identified by match to protein family HMM PF00102; match to protein family HMM PF03545; match to protein family HMM PF09119 YP_002115832.1 identified by match to protein family HMM PF05932 YP_002115834.1 carries the fatty acid chain in fatty acid biosynthesis YP_002115835.1 identified by match to protein family HMM PF09052 YP_002115836.1 identified by match to protein family HMM PF06511; match to protein family HMM TIGR02553 YP_002115837.1 identified by match to protein family HMM PF03518 YP_002115838.1 identified by match to protein family HMM PF07720; match to protein family HMM TIGR02552 YP_002115839.1 Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins YP_002115840.1 identified by match to protein family HMM PF01311; match to protein family HMM TIGR01401 YP_002115841.1 identified by match to protein family HMM PF01313; match to protein family HMM TIGR01403 YP_002115842.1 part of a type III secretory system probably involved in invasion into eukaryotic cells YP_002115843.1 involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells YP_002115844.1 identified by match to protein family HMM PF02510 YP_002115845.1 identified by match to protein family HMM PF02090 YP_002115846.1 Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase YP_002115847.1 identified by match to protein family HMM PF03519 YP_002115848.1 identified by match to protein family HMM PF00771; match to protein family HMM TIGR01399 YP_002115849.1 identified by match to protein family HMM PF02523; match to protein family HMM TIGR02568 YP_002115850.2 identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02516 YP_002115851.1 identified by match to protein family HMM PF00165 YP_002115852.1 identified by glimmer YP_002115853.1 identified by match to protein family HMM PF04741 YP_002115855.1 identified by match to protein family HMM PF00149 YP_002115858.1 This protein performs the mismatch recognition step during the DNA repair process YP_002115860.1 identified by match to protein family HMM PF07690 YP_002115861.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002115862.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM PF06808; match to protein family HMM TIGR00791 YP_002115863.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_002115864.1 identified by match to protein family HMM PF01261 YP_002115865.1 identified by match to protein family HMM PF00596 YP_002115866.1 identified by match to protein family HMM PF07005 YP_002115867.1 identified by match to protein family HMM PF03446 YP_002115868.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002115869.1 identified by match to protein family HMM PF01047 YP_002115870.1 identified by match to protein family HMM PF02441; match to protein family HMM TIGR00421 YP_002115871.1 identified by match to protein family HMM PF01977; match to protein family HMM TIGR00148 YP_002115873.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_002115874.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus YP_002115875.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_002115876.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_002115877.1 catalyzes the modification of U13 in tRNA(Glu) YP_002115878.1 'catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate' YP_002115879.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_002115880.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_002115882.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_002115883.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_002115884.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_002115885.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 YP_002115888.1 identified by match to protein family HMM TIGR00287 YP_002115889.1 identified by match to protein family HMM PF08798; match to protein family HMM TIGR01907 YP_002115890.1 identified by match to protein family HMM PF09708; match to protein family HMM TIGR01868; match to protein family HMM TIGR02593 YP_002115891.1 identified by match to protein family HMM PF09344; match to protein family HMM TIGR01869 YP_002115892.1 identified by match to protein family HMM PF09485; match to protein family HMM TIGR02548 YP_002115893.1 identified by match to protein family HMM PF09481; match to protein family HMM TIGR02547 YP_002115895.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_002115896.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_002115897.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity YP_002115898.1 identified by match to protein family HMM PF01242; match to protein family HMM TIGR00039; match to protein family HMM TIGR03367 YP_002115899.1 identified by match to protein family HMM PF00753 YP_002115901.1 identified by glimmer YP_002115902.1 identified by match to protein family HMM PF04055 YP_002115903.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_002115904.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_002115905.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_002115906.1 identified by match to protein family HMM PF05016 YP_002115907.1 identified by match to protein family HMM PF01402; match to protein family HMM PF03693; match to protein family HMM TIGR02606 YP_002115908.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_002115909.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_002115910.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_002115911.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_002115912.1 identified by match to protein family HMM PF01188; match to protein family HMM TIGR03247 YP_002115913.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002115914.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00893 YP_002115915.1 'An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group' YP_002115916.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_002115917.1 identified by match to protein family HMM PF04287 YP_002115918.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_002115919.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_002115920.1 identified by match to protein family HMM PF03641 YP_002115921.1 identified by match to protein family HMM TIGR00814 YP_002115922.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_002115923.2 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_002115924.1 identified by match to protein family HMM PF00465; match to protein family HMM TIGR02638 YP_002115925.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_002115927.1 identified by glimmer YP_002115928.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00885 YP_002115929.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose YP_002115930.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR02628 YP_002115931.1 identified by match to protein family HMM PF05025 YP_002115932.1 regulates expression of genes involved in L-fucose utilization YP_002115934.1 identified by match to protein family HMM PF04241 YP_002115935.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_002115936.1 identified by match to protein family HMM PF06004 YP_002115937.1 identified by match to protein family HMM PF00266; match to protein family HMM TIGR03392 YP_002115938.1 identified by match to protein family HMM PF02657; match to protein family HMM TIGR03391 YP_002115939.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688 YP_002115940.1 identified by match to protein family HMM PF00899 YP_002115941.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_002115942.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_002115943.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_002115944.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_002115945.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_002115947.1 alternate name YgdB, URF2; orf of X03966; 2nd start; ORF_f121 YP_002115949.1 identified by match to protein family HMM TIGR02532 YP_002115951.1 'ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived' YP_002115952.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_002115953.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_002115954.1 hydrolyzes diadenosine polyphosphate YP_002115955.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_002115956.1 identified by glimmer YP_002115957.1 identified by match to protein family HMM PF03741 YP_002115958.1 identified by match to protein family HMM PF06004 YP_002115959.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_002115960.1 identified by match to protein family HMM PF07690 YP_002115961.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_002115963.1 controls transcription of galETKM YP_002115964.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002115965.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_002115966.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_002115967.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035 YP_002115968.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879 YP_002115969.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate YP_002115970.1 '4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate' YP_002115971.1 identified by glimmer YP_002115972.1 'Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis' YP_002115973.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002115974.1 identified by match to protein family HMM PF05232 YP_002115976.1 identified by match to protein family HMM PF02583 YP_002115977.1 membrane protein conferring nickel and cobalt resistance YP_002115979.1 identified by match to protein family HMM PF07180 YP_002115980.1 identified by match to protein family HMM PF00345 YP_002115981.1 identified by match to protein family HMM PF00577 YP_002115982.1 identified by match to protein family HMM PF00419 YP_002115984.1 identified by match to protein family HMM PF06316 YP_002115986.1 identified by glimmer YP_002115987.1 identified by match to protein family HMM PF07313 YP_002115988.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551 YP_002115989.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate YP_002115990.1 'class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1' YP_002115991.1 5'-3' single-stranded-DNA-specific exonuclease YP_002115992.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_002115993.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002115994.1 'An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic' YP_002115995.1 identified by match to protein family HMM PF07254 YP_002115996.1 identified by match to protein family HMM PF03937 YP_002115997.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator YP_002115998.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065 YP_002115999.1 identified by match to protein family HMM PF04266 YP_002116000.1 identified by match to protein family HMM PF00232 YP_002116002.1 'part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor' YP_002116003.1 'catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein' YP_002116004.1 identified by glimmer YP_002116005.1 identified by match to protein family HMM PF01494; match to protein family HMM TIGR01988 YP_002116006.1 'Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone' YP_002116007.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_002116008.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_002116010.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function YP_002116011.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_002116012.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_002116013.1 identified by match to protein family HMM PF04402 YP_002116014.1 Involved in the export of arginine YP_002116015.1 participates in the regulation of osmotic pressure changes within the cel YP_002116016.1 'catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate' YP_002116017.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_002116018.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_002116019.1 identified by match to protein family HMM PF03479 YP_002116021.1 identified by match to protein family HMM PF02361 YP_002116022.1 identified by match to protein family HMM PF00005 YP_002116023.1 identified by match to protein family HMM PF00005 YP_002116025.1 identified by match to protein family HMM PF05068 YP_002116026.1 identified by match to protein family HMM PF03320; match to protein family HMM TIGR00330 YP_002116027.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002116028.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378 YP_002116029.1 'TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein' YP_002116030.1 identified by glimmer YP_002116031.1 'catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase' YP_002116032.1 catalyzes the formation of putrescine from agmatine YP_002116033.1 identified by glimmer YP_002116034.2 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_002116037.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_002116038.1 identified by glimmer YP_002116039.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879 YP_002116040.1 identified by match to protein family HMM PF03926 YP_002116041.1 identified by match to protein family HMM PF04231 YP_002116042.1 'in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase' YP_002116043.1 'catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione' YP_002116044.1 identified by match to protein family HMM PF02622 YP_002116045.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_002116046.1 identified by match to protein family HMM PF09339 YP_002116047.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420 YP_002116048.1 identified by match to protein family HMM PF01168; match to protein family HMM TIGR00044 YP_002116049.1 identified by match to protein family HMM PF02325 YP_002116050.1 identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251 YP_002116051.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_002116052.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002116053.1 identified by match to protein family HMM PF06717 YP_002116054.1 'catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis' YP_002116056.1 identified by match to protein family HMM PF04320 YP_002116057.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_002116058.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084 YP_002116059.1 identified by match to protein family HMM PF04362 YP_002116060.1 'Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues' YP_002116061.1 identified by glimmer YP_002116062.1 identified by match to protein family HMM PF03825; match to protein family HMM TIGR00889 YP_002116063.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_002116064.1 identified by glimmer YP_002116065.1 identified by match to protein family HMM PF04474 YP_002116066.1 identified by match to protein family HMM PF02550 YP_002116067.1 identified by match to protein family HMM PF01575 YP_002116068.1 identified by match to protein family HMM PF03328 YP_002116069.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002116070.1 identified by match to protein family HMM PF00884 YP_002116071.1 identified by match to protein family HMM PF04055 YP_002116072.1 identified by match to protein family HMM PF00196 YP_002116074.1 identified by match to protein family HMM PF00324 YP_002116075.1 identified by glimmer YP_002116076.1 identified by match to protein family HMM PF05899 YP_002116077.1 identified by match to protein family HMM PF01266 YP_002116078.1 identified by match to protein family HMM PF00171 YP_002116079.2 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS YP_002116080.1 identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344 YP_002116081.1 identified by glimmer YP_002116083.1 identified by match to protein family HMM PF01522 YP_002116084.1 identified by match to protein family HMM PF00795 YP_002116085.1 identified by match to protein family HMM PF00440 YP_002116086.1 identified by match to protein family HMM PF00703; match to protein family HMM PF02836; match to protein family HMM PF02837 YP_002116087.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00792 YP_002116089.1 identified by match to protein family HMM PF07690 YP_002116090.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_002116091.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_002116092.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_002116093.1 identified by match to protein family HMM PF00015 YP_002116094.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction YP_002116095.1 YghU; B2989; one of eight glutathione transferase proteins from E. coli YP_002116097.1 identified by match to protein family HMM PF01497 YP_002116098.1 identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074 YP_002116099.1 plays a role in hydrogenase nickel cofactor insertion YP_002116101.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC) YP_002116102.1 involved in hydrogen uptake YP_002116103.1 'HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits' YP_002116104.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2 YP_002116105.1 involved in hydrogen uptake YP_002116108.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002116109.1 identified by match to protein family HMM PF03350; match to protein family HMM TIGR00645 YP_002116113.1 identified by match to protein family HMM PF00106 YP_002116114.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_002116115.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_002116117.1 catalyzes the formation of L-homocysteine from cystathionine YP_002116118.1 identified by match to protein family HMM PF09335 YP_002116119.1 identified by glimmer YP_002116120.1 identified by match to protein family HMM PF00465 YP_002116121.1 'methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate' YP_002116122.1 identified by match to protein family HMM PF01230 YP_002116123.1 identified by match to protein family HMM PF04055; match to protein family HMM PF08497 YP_002116127.1 identified by match to protein family HMM PF07731; match to protein family HMM PF07732; match to protein family HMM TIGR01409 YP_002116128.1 identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530 YP_002116129.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002116130.1 identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156 YP_002116131.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes YP_002116132.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002116133.1 identified by match to protein family HMM PF02525 YP_002116134.1 identified by match to protein family HMM PF03992 YP_002116135.1 identified by glimmer YP_002116136.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002116137.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_002116138.1 identified by match to protein family HMM PF00149; match to protein family HMM PF08413 YP_002116139.1 identified by match to protein family HMM PF06853 YP_002116140.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_002116141.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_002116143.1 identified by match to protein family HMM PF03738 YP_002116144.1 'seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine' YP_002116145.1 identified by match to protein family HMM PF02535 YP_002116147.1 identified by match to protein family HMM PF05935 YP_002116148.1 identified by match to protein family HMM PF01323 YP_002116151.1 identified by match to protein family HMM PF00665 YP_002116152.1 DHBP synthase; functions during riboflavin biosynthesis YP_002116153.1 identified by match to protein family HMM PF04380 YP_002116154.1 Involved in glycogen synthesis. May be involved in glycogen priming YP_002116155.1 identified by match to protein family HMM PF07290 YP_002116156.1 identified by match to protein family HMM PF01145 YP_002116157.1 'catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose' YP_002116158.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_002116159.1 identified by match to protein family HMM PF01928; match to protein family HMM PF05235 YP_002116160.1 identified by match to protein family HMM PF08239 YP_002116161.1 'catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases' YP_002116162.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell YP_002116163.1 'catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin' YP_002116164.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_002116165.1 'in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity' YP_002116166.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_002116167.1 synthesizes RNA primers at the replication forks YP_002116168.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_002116169.1 identified by match to protein family HMM PF03167 YP_002116170.1 identified by match to protein family HMM PF04954; match to protein family HMM PF08021 YP_002116171.1 identified by match to protein family HMM PF03551 YP_002116172.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002116173.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF08447; match to protein family HMM TIGR00229 YP_002116175.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate YP_002116176.1 identified by match to protein family HMM PF00724; match to protein family HMM PF07992 YP_002116177.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08242 YP_002116178.1 identified by match to protein family HMM PF01863 YP_002116179.2 identified by match to protein family HMM PF02698 YP_002116180.1 identified by match to protein family HMM PF01408 YP_002116181.1 identified by match to protein family HMM PF03741 YP_002116182.1 involved in the import of serine and threonine coupled with the import of sodium YP_002116183.1 identified by match to protein family HMM PF09335 YP_002116185.1 identified by match to protein family HMM PF06476 YP_002116186.1 identified by match to protein family HMM PF05957 YP_002116189.1 identified by match to protein family HMM PF07681 YP_002116191.1 identified by match to protein family HMM PF05656 YP_002116192.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002116193.1 identified by match to protein family HMM PF02678 YP_002116195.1 identified by match to protein family HMM PF06354 YP_002116196.1 identified by match to protein family HMM TIGR00814 YP_002116197.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_002116198.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_002116199.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism YP_002116200.1 involved in the import of threonine and serine in combination with the import of a proton YP_002116201.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic YP_002116202.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation YP_002116203.1 identified by glimmer YP_002116204.1 catalyzes the reduction of tartronate semialdehyde to glycerate YP_002116205.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate YP_002116206.1 identified by glimmer YP_002116207.1 identified by match to protein family HMM PF04295; match to protein family HMM PF08666; match to protein family HMM TIGR03248 YP_002116208.1 'catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway' YP_002116209.1 identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810 YP_002116210.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002116211.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002116212.1 identified by match to protein family HMM PF03611; match to protein family HMM TIGR00827 YP_002116213.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate YP_002116214.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002116215.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096 YP_002116216.1 identified by match to protein family HMM PF04348 YP_002116217.1 identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252 YP_002116218.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_002116219.1 identified by match to protein family HMM PF04972 YP_002116220.1 identified by match to protein family HMM PF01370; match to protein family HMM PF07993 YP_002116221.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382 YP_002116223.1 identified by match to protein family HMM PF01541 YP_002116224.1 identified by match to protein family HMM PF00583 YP_002116225.1 identified by match to protein family HMM PF02036 YP_002116226.1 identified by match to protein family HMM PF01136 YP_002116227.1 identified by match to protein family HMM PF01136 YP_002116228.1 identified by match to protein family HMM PF00296; match to protein family HMM TIGR03558 YP_002116229.1 tryptophan transporter of high affinity YP_002116230.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_002116231.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_002116232.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_002116233.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_002116234.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_002116235.1 identified by glimmer YP_002116236.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_002116237.1 'modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination' YP_002116238.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_002116239.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_002116240.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810 YP_002116241.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_002116242.1 'catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate' YP_002116243.1 identified by glimmer YP_002116244.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins YP_002116245.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_002116246.1 RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability YP_002116247.1 'necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus' YP_002116248.1 identified by glimmer YP_002116249.1 'penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains' YP_002116250.1 identified by glimmer YP_002116251.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_002116252.1 identified by match to protein family HMM PF00892 YP_002116253.1 involved in the peptidyltransferase reaction during translation YP_002116254.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061 YP_002116255.2 identified by match to protein family HMM PF00348 YP_002116256.1 activator of maltose metabolism genes YP_002116257.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002116258.1 identified by match to protein family HMM PF01722 YP_002116260.1 identified by match to protein family HMM PF05494 YP_002116261.1 identified by match to protein family HMM PF02470 YP_002116262.1 identified by match to protein family HMM PF02405; match to protein family HMM TIGR00056 YP_002116263.1 ATP-binding subunit of a ABC toluene efflux transporter YP_002116264.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_002116265.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393 YP_002116266.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_002116267.1 identified by match to protein family HMM PF06835 YP_002116268.1 'LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system' YP_002116269.1 identified by match to protein family HMM PF00005 YP_002116270.1 'sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen' YP_002116271.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing YP_002116272.1 identified by match to protein family HMM PF00359; match to protein family HMM TIGR01419 YP_002116273.1 identified by match to protein family HMM PF03668 YP_002116274.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_002116276.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_002116277.1 identified by match to protein family HMM PF01965 YP_002116278.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_002116279.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR01212 YP_002116280.1 'glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate' YP_002116281.1 identified by match to protein family HMM PF06250 YP_002116282.1 identified by match to protein family HMM PF02133 YP_002116283.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_002116284.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_002116285.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein YP_002116286.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_002116287.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00891 YP_002116288.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid YP_002116289.2 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization YP_002116290.1 identified by match to protein family HMM PF04386 YP_002116291.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_002116292.1 forms a direct contact with the tRNA during translation YP_002116293.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_002116294.1 identified by match to protein family HMM PF03969 YP_002116295.1 identified by match to protein family HMM PF06295 YP_002116296.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037 YP_002116297.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02038 YP_002116299.1 identified by match to protein family HMM PF03977; match to protein family HMM TIGR01109 YP_002116300.1 catalyzes the formation of pyruvate from oxaloacetate YP_002116301.1 catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide YP_002116302.1 Involved in the tartrate degradation pathway YP_002116303.1 Involved in the tartrate degradation pathway YP_002116304.1 identified by match to protein family HMM PF00939; match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM PF06808; match to protein family HMM TIGR00785 YP_002116305.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002116306.1 identified by match to protein family HMM PF00392 YP_002116307.1 oxidizes malate to oxaloacetate YP_002116308.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_002116309.1 identified by match to protein family HMM PF07338 YP_002116310.1 identified by match to protein family HMM PF07338 YP_002116312.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_002116313.1 'with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate' YP_002116314.1 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_002116315.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002116316.1 'responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA' YP_002116317.1 identified by match to protein family HMM TIGR02099 YP_002116318.1 involved in the processing of the 5'end of 16S rRNA YP_002116319.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002116320.1 part of cell wall structural complex MreBCD; transmembrane component YP_002116321.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_002116322.1 functions in MreBCD complex in some organisms YP_002116323.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_002116324.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02823 YP_002116325.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_002116326.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_002116327.1 'composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism' YP_002116328.1 'an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism' YP_002116329.1 identified by match to protein family HMM PF06196 YP_002116330.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_002116331.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_002116332.1 identified by match to protein family HMM PF01207; match to protein family HMM TIGR00737 YP_002116333.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_002116334.1 identified by match to protein family HMM PF01555 YP_002116336.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF03707; match to protein family HMM TIGR00254 YP_002116337.1 identified by match to protein family HMM PF00440; match to protein family HMM PF08361 YP_002116338.1 identified by glimmer YP_002116339.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_002116340.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_002116343.1 identified by glimmer YP_002116344.1 identified by match to protein family HMM PF07369 YP_002116345.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_002116346.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA YP_002116347.1 identified by match to protein family HMM PF01396 YP_002116348.1 identified by match to protein family HMM PF04361 YP_002116349.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732 YP_002116350.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002116351.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_002116352.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_002116353.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_002116354.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_002116355.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_002116356.1 identified by match to protein family HMM PF09350 YP_002116357.1 is a component of the macrolide binding site in the peptidyl transferase center YP_002116358.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_002116359.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_002116360.1 'located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3' YP_002116361.1 'located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA' YP_002116362.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_002116363.1 late assembly protein YP_002116364.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_002116365.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_002116366.1 binds 5S rRNA along with protein L5 and L25 YP_002116367.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_002116368.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_002116369.1 'located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif' YP_002116370.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_002116371.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_002116372.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_002116373.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_002116374.1 one of the stabilizing components for the large ribosomal subunit YP_002116375.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_002116376.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_002116377.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_002116378.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_002116379.1 'one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation' YP_002116380.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_002116381.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_002116382.1 'binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin' YP_002116383.1 identified by match to protein family HMM PF00338; match to protein family HMM TIGR01049 YP_002116384.1 identified by match to protein family HMM PF01478 YP_002116385.1 iron storage protein YP_002116386.1 identified by match to protein family HMM PF04324 YP_002116387.1 'EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu' YP_002116388.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_002116389.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_002116390.1 'interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance' YP_002116391.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002116392.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002116393.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002116394.1 identified by match to protein family HMM PF08348 YP_002116395.1 rotamase YP_002116396.1 identified by match to protein family HMM PF04102 YP_002116397.1 rotamase YP_002116398.1 identified by match to protein family HMM PF09526; match to protein family HMM TIGR02443 YP_002116399.1 involved in potassium efflux YP_002116400.1 required for KefB activity YP_002116401.1 identified by match to protein family HMM PF00005 YP_002116403.1 identified by match to protein family HMM PF08803 YP_002116404.2 identified by match to protein family HMM PF00561 YP_002116405.1 identified by match to protein family HMM PF06794 YP_002116406.1 identified by match to protein family HMM PF00485 YP_002116407.1 identified by match to protein family HMM PF02566 YP_002116408.1 identified by glimmer YP_002116409.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_002116410.1 identified by match to protein family HMM PF05976; match to protein family HMM TIGR01667 YP_002116411.1 'DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate' YP_002116412.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_002116413.1 identified by match to protein family HMM PF02661 YP_002116415.1 identified by match to protein family HMM PF00160 YP_002116416.1 identified by match to protein family HMM PF07690 YP_002116418.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374 YP_002116419.1 'involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations' YP_002116420.1 member of the FNT family of formate and nitrite transporters YP_002116421.1 'multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin' YP_002116422.1 identified by match to protein family HMM PF03797 YP_002116424.1 'catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA' YP_002116425.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_002116426.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_002116427.1 identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571 YP_002116428.1 identified by match to protein family HMM PF05036 YP_002116429.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_002116430.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_002116433.1 identified by match to protein family HMM PF05137 YP_002116434.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_002116435.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_002116436.1 identified by match to protein family HMM PF07095 YP_002116437.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509 YP_002116438.1 identified by match to protein family HMM PF01479 YP_002116439.1 'becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers' YP_002116441.1 identified by glimmer YP_002116442.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_002116443.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_002116444.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_002116445.1 'necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus' YP_002116446.1 identified by match to protein family HMM PF00575; match to protein family HMM PF09371 YP_002116447.1 identified by match to protein family HMM PF04023 YP_002116448.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake YP_002116449.1 identified by match to protein family HMM PF09012 YP_002116450.1 identified by glimmer YP_002116451.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_002116452.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis YP_002116453.1 involved in high-affinity gluconate transport YP_002116454.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_002116455.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_002116456.1 amylomaltase; acts to release glucose from maltodextrins YP_002116457.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_002116458.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides YP_002116459.1 'represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism' YP_002116460.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_002116461.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine YP_002116462.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_002116466.1 identified by glimmer YP_002116467.1 identified by glimmer YP_002116468.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_002116469.1 'catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose' YP_002116470.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_002116471.1 'catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen' YP_002116472.1 'catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain' YP_002116473.2 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002116474.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_002116475.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate YP_002116476.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002116477.1 identified by match to protein family HMM PF02678; match to protein family HMM PF07883 YP_002116478.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002116479.1 YhhY; regulated by the fur regulator; unknown function YP_002116480.1 identified by glimmer YP_002116481.1 identified by match to protein family HMM PF00294; match to protein family HMM PF08220; match to protein family HMM PF08543 YP_002116482.1 identified by match to protein family HMM PF07090 YP_002116484.1 identified by match to protein family HMM PF02126 YP_002116485.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides YP_002116487.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_002116488.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_002116489.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_002116490.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_002116491.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_002116492.1 identified by glimmer YP_002116494.1 'with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine' YP_002116495.1 'Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine' YP_002116496.1 'Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine' YP_002116497.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_002116498.1 identified by match to protein family HMM PF01094 YP_002116499.1 identified by glimmer YP_002116500.1 identified by match to protein family HMM PF00583 YP_002116502.1 identified by match to protein family HMM PF01094 YP_002116503.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_002116504.1 'ABC transporter, membrane protein' YP_002116505.1 'ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions' YP_002116506.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins YP_002116507.1 catalyzes the methylation of 16S rRNA at position G966 YP_002116508.1 identified by match to protein family HMM PF06611 YP_002116510.1 identified by match to protein family HMM PF07947 YP_002116511.1 'P-type ATPase involved in the export of lead, cadmium, zinc and mercury' YP_002116512.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_002116513.1 identified by match to protein family HMM PF01206 YP_002116514.1 identified by match to protein family HMM PF02592; match to protein family HMM TIGR00697 YP_002116516.1 identified by match to protein family HMM PF07690 YP_002116517.1 identified by match to protein family HMM PF01594 YP_002116518.1 identified by match to protein family HMM PF01648 YP_002116519.1 Inhibits transcription at high concentrations of nickel YP_002116520.1 identified by match to protein family HMM PF01061 YP_002116521.1 identified by match to protein family HMM PF00005; match to protein family HMM PF01061 YP_002116522.1 identified by match to protein family HMM PF00529 YP_002116523.1 identified by glimmer YP_002116524.1 identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275 YP_002116525.1 identified by match to protein family HMM PF01384 YP_002116526.1 'ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress' YP_002116527.1 identified by match to protein family HMM PF00582 YP_002116528.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function YP_002116529.1 predicted SAM-dependent methyltransferase YP_002116530.1 identified by match to protein family HMM PF01432 YP_002116531.1 identified by match to protein family HMM PF01569 YP_002116532.1 identified by match to protein family HMM PF04378 YP_002116533.1 identified by glimmer YP_002116534.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_002116535.1 identified by match to protein family HMM PF00710; match to protein family HMM TIGR00520 YP_002116536.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_002116537.1 identified by match to protein family HMM PF00294 YP_002116538.1 identified by match to protein family HMM PF01380 YP_002116539.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002116540.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose YP_002116543.1 identified by match to protein family HMM PF00196; match to protein family HMM PF01726; match to protein family HMM PF08281 YP_002116544.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002116545.1 identified by match to protein family HMM PF03631; match to protein family HMM TIGR00766 YP_002116546.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_002116547.1 identified by match to protein family HMM PF05170 YP_002116548.1 in Escherichia coli this protein is involved in flagellar function YP_002116550.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_002116551.1 involved in the transport of C4-dicarboxylates across the membrane YP_002116552.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase protein from E. coli YP_002116553.1 'cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA' YP_002116554.1 'catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans' YP_002116555.1 'binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP)' YP_002116556.1 'polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis' YP_002116557.1 identified by match to protein family HMM PF06564; match to protein family HMM TIGR03371 YP_002116559.1 identified by match to protein family HMM TIGR03369 YP_002116560.1 identified by match to protein family HMM TIGR03493 YP_002116561.1 identified by match to protein family HMM TIGR03368 YP_002116564.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_002116565.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF YP_002116566.1 identified by match to protein family HMM PF00528 YP_002116567.1 transports peptides consisting of two or three amino acids YP_002116568.1 identified by match to protein family HMM PF00496 YP_002116569.1 identified by match to protein family HMM PF00860 YP_002116571.1 identified by glimmer YP_002116572.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002116573.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_002116575.1 'constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine' YP_002116576.1 identified by match to protein family HMM PF00583 YP_002116577.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509 YP_002116578.1 identified by match to protein family HMM PF00691; match to protein family HMM PF05433 YP_002116579.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_002116581.1 identified by glimmer YP_002116583.1 identified by match to protein family HMM PF00313 YP_002116585.1 identified by match to protein family HMM PF08681 YP_002116586.1 identified by glimmer YP_002116587.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002116588.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002116589.1 identified by glimmer YP_002116591.1 identified by match to protein family HMM PF01757 YP_002116592.1 identified by match to protein family HMM PF05360 YP_002116593.1 catalyzes the interconversion of D-xylose to D-xylulose YP_002116594.1 identified by glimmer YP_002116595.1 identified by match to protein family HMM PF00165 YP_002116596.1 identified by match to protein family HMM PF01832 YP_002116597.1 identified by glimmer YP_002116598.1 'periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds' YP_002116599.1 'transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis' YP_002116600.1 identified by match to protein family HMM PF00037 YP_002116601.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_002116602.1 'NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate' YP_002116603.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_002116605.1 'membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO' YP_002116606.1 identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786 YP_002116607.1 identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787 YP_002116608.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_002116609.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate YP_002116610.1 'L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate' YP_002116611.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_002116612.1 identified by match to protein family HMM PF00165 YP_002116613.1 identified by match to protein family HMM PF07944 YP_002116615.1 identified by match to protein family HMM PF00171 YP_002116616.1 identified by match to protein family HMM PF00480 YP_002116617.1 identified by match to protein family HMM PF00465 YP_002116618.1 identified by match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM PF09106; match to protein family HMM PF09107; match to protein family HMM TIGR00475 YP_002116619.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_002116620.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_002116621.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851 YP_002116622.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_002116623.1 Acts as a repressor of the mtlAD operon YP_002116626.1 identified by glimmer YP_002116628.1 identified by match to protein family HMM PF03895; match to protein family HMM PF05658; match to protein family HMM PF05662 YP_002116629.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795 YP_002116630.1 represses the lctPRD operon YP_002116631.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_002116632.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates YP_002116633.1 identified by glimmer YP_002116634.1 catalyzes the O-acetylation of serine YP_002116635.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_002116636.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_002116637.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02181 YP_002116638.1 identified by match to protein family HMM PF00581 YP_002116639.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_002116640.1 identified by match to protein family HMM PF01551 YP_002116641.1 identified by match to protein family HMM PF04748 YP_002116642.1 identified by match to protein family HMM PF00535 YP_002116643.1 'converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism' YP_002116644.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_002116645.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_002116646.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_002116647.1 identified by match to protein family HMM PF01075; match to protein family HMM TIGR02193 YP_002116648.1 identified by match to protein family HMM PF04932 YP_002116649.1 identified by match to protein family HMM PF00534 YP_002116651.1 identified by match to protein family HMM PF06176 YP_002116652.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08437 YP_002116653.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08437 YP_002116654.1 identified by match to protein family HMM PF00534 YP_002116655.1 identified by match to protein family HMM PF07922 YP_002116656.1 identified by match to protein family HMM PF06293 YP_002116657.1 identified by match to protein family HMM PF00534 YP_002116658.1 identified by match to protein family HMM PF01075; match to protein family HMM TIGR02201 YP_002116659.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_002116660.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_002116661.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_002116662.1 'in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif' YP_002116663.1 required for 70S ribosome assembly YP_002116664.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_002116665.1 catalyzes the formation of dUMP from dUTP YP_002116666.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_002116667.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002116668.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_002116669.1 identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255 YP_002116670.1 identified by match to protein family HMM PF00589 YP_002116673.1 identified by glimmer YP_002116676.1 identified by glimmer YP_002116678.1 identified by match to protein family HMM PF00126 YP_002116679.1 identified by match to protein family HMM PF00753 YP_002116680.1 identified by glimmer YP_002116681.1 identified by match to protein family HMM PF03458 YP_002116682.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_002116683.1 'Essential for recycling GMP and indirectly, cGMP' YP_002116684.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_002116685.1 identified by match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691 YP_002116686.1 specifically modifies tRNA at position G18 YP_002116687.1 catalyzes branch migration in Holliday junction intermediates YP_002116688.1 identified by match to protein family HMM PF03616; match to protein family HMM TIGR00210 YP_002116689.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_002116690.1 identified by match to protein family HMM PF05170 YP_002116691.1 'catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides' YP_002116692.1 may be involved in the transport of galactosides-pentoses-hexuronides YP_002116696.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_002116698.1 identified by match to protein family HMM PF00486 YP_002116699.1 identified by glimmer YP_002116700.1 identified by match to protein family HMM PF00857 YP_002116702.1 identified by glimmer YP_002116703.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01524 YP_002116704.1 identified by glimmer YP_002116705.1 identified by match to protein family HMM PF02308 YP_002116706.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950 YP_002116707.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_002116708.1 identified by match to protein family HMM PF07071; match to protein family HMM TIGR03581 YP_002116709.1 identified by match to protein family HMM PF03841; match to protein family HMM TIGR01437 YP_002116710.1 identified by match to protein family HMM PF03613 YP_002116711.1 identified by match to protein family HMM PF03609 YP_002116712.1 identified by match to protein family HMM PF03830 YP_002116713.1 identified by match to protein family HMM PF03610 YP_002116714.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00874; match to protein family HMM PF07728 YP_002116715.1 identified by glimmer YP_002116717.1 identified by match to protein family HMM PF00232 YP_002116718.1 identified by match to protein family HMM PF06296 YP_002116719.1 identified by match to protein family HMM PF01381 YP_002116722.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_002116723.1 'class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis' YP_002116724.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_002116725.1 identified by match to protein family HMM PF03611 YP_002116727.1 identified by match to protein family HMM PF00359 YP_002116728.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002116729.1 identified by match to protein family HMM PF06711 YP_002116730.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate YP_002116731.1 membrane protein regulates uhpT expression YP_002116732.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph YP_002116733.1 'response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter' YP_002116735.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00885 YP_002116736.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR02152 YP_002116737.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002116738.1 'with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit' YP_002116739.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118 YP_002116740.1 identified by match to protein family HMM PF00892 YP_002116741.1 multidrug efflux protein involved in adaptation to low energy shock YP_002116742.1 regulates the synthesis and expression of the dsdXA operon and dadA gene YP_002116743.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_002116744.1 catalyzes the formation of pyruvate from serine YP_002116747.1 identified by match to protein family HMM PF02656 YP_002116748.1 identified by glimmer YP_002116749.1 identified by glimmer YP_002116750.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625 YP_002116751.1 '16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent' YP_002116752.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_002116754.1 identified by match to protein family HMM PF07119 YP_002116755.1 identified by match to protein family HMM PF03918 YP_002116756.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR00385 YP_002116757.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR00353 YP_002116758.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_002116759.1 identified by match to protein family HMM PF04995; match to protein family HMM TIGR03141 YP_002116760.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR01191 YP_002116761.1 identified by match to protein family HMM PF03379; match to protein family HMM TIGR01190 YP_002116762.1 ATP-binding protein; required for proper cytochrome c maturation YP_002116763.1 identified by match to protein family HMM PF03150 YP_002116764.1 'TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor' YP_002116765.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409; match to protein family HMM TIGR02164 YP_002116766.1 identified by match to protein family HMM PF03264; match to protein family HMM TIGR02162 YP_002116767.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes YP_002116768.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_002116769.1 identified by glimmer YP_002116770.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide YP_002116774.1 identified by glimmer YP_002116775.1 'YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins' YP_002116776.1 identified by match to protein family HMM PF07690 YP_002116777.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002116778.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002116779.1 negatively supercoils closed circular double-stranded DNA YP_002116780.1 'Required for DNA replication; binds preferentially to single-stranded, linear DNA' YP_002116781.1 binds the polymerase to DNA and acts as a sliding clamp YP_002116782.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_002116783.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_002116784.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_002116785.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_002116786.1 'in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE' YP_002116787.1 Confers resistance to chloramphenicol YP_002116788.1 Involved in anaerobic NO protection YP_002116790.1 identified by match to protein family HMM PF03358 YP_002116791.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_002116792.1 'YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily' YP_002116793.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_002116794.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002116795.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_002116796.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_002116797.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00975 YP_002116798.1 identified by match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR01427 YP_002116799.1 catalyzes the conversion of shikimate to 3-dehydroshikimate YP_002116800.1 identified by match to protein family HMM PF00496 YP_002116801.1 'Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source' YP_002116802.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_002116803.1 identified by glimmer YP_002116805.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_002116806.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_002116807.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_002116808.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002116809.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_002116810.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_002116811.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_002116812.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_002116815.1 identified by glimmer YP_002116816.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_002116817.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_002116818.1 'An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group' YP_002116819.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_002116820.1 catalyzes the formation of asparagine from aspartate and ammonia YP_002116821.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_002116822.1 'interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase' YP_002116823.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_002116824.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_002116825.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_002116826.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_002116827.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_002116828.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_002116829.1 DNA-binding transcriptional repressor of ribose metabolism YP_002116830.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002116831.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002116832.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_002116833.1 identified by match to protein family HMM PF04219 YP_002116834.1 'among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function' YP_002116835.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_002116837.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_002116838.1 'catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis' YP_002116839.1 'threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway' YP_002116840.1 identified by match to protein family HMM PF09365 YP_002116842.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_002116843.1 'catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis' YP_002116844.1 identified by match to protein family HMM PF00639 YP_002116845.1 identified by match to protein family HMM PF00027 YP_002116846.1 identified by match to protein family HMM PF01048 YP_002116847.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528 YP_002116848.2 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_002116849.1 'catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation' YP_002116850.1 'enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation' YP_002116851.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_002116852.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_002116853.1 identified by match to protein family HMM PF00953; match to protein family HMM TIGR02380 YP_002116854.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein YP_002116855.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236 YP_002116856.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid YP_002116857.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181 YP_002116858.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207 YP_002116859.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR02382 YP_002116860.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_002116861.1 identified by match to protein family HMM PF01943 YP_002116862.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_002116863.1 enterobacterial common antigen polymerase YP_002116864.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696 YP_002116865.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function YP_002116866.1 identified by glimmer YP_002116867.1 identified by match to protein family HMM PF07219; match to protein family HMM PF07719; match to protein family HMM TIGR00540 YP_002116868.1 identified by match to protein family HMM PF04375 YP_002116869.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_002116870.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_002116871.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_002116872.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_002116876.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_002116877.1 identified by match to protein family HMM PF04340 YP_002116878.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002116879.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function YP_002116880.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_002116881.1 responsible for the influx of magnesium ions YP_002116882.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688 YP_002116883.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_002116884.1 catalyzes the hydrolysis of phosphatidylcholine YP_002116885.1 'functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway' YP_002116886.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_002116887.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_002116888.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_002116889.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002116890.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_002116891.1 identified by glimmer YP_002116892.1 identified by match to protein family HMM PF02810; match to protein family HMM PF04055 YP_002116893.2 identified by match to protein family HMM PF01738 YP_002116894.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_002116895.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner YP_002116896.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_002116897.1 identified by match to protein family HMM PF02036 YP_002116898.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_002116899.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_002116900.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_002116901.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_002116902.1 magnesium dependent; not involved in the Sec-independent protein export system YP_002116903.1 identified by match to protein family HMM PF02357; match to protein family HMM TIGR01955 YP_002116904.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol YP_002116905.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_002116906.1 identified by match to protein family HMM PF05935 YP_002116907.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_002116908.1 'includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids' YP_002116909.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_002116910.1 identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257 YP_002116911.1 identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933 YP_002116912.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_002116913.1 identified by glimmer YP_002116914.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway YP_002116915.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_002116916.1 identified by match to protein family HMM PF06288 YP_002116917.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_002116918.1 identified by match to protein family HMM PF01323 YP_002116919.1 identified by match to protein family HMM PF01553 YP_002116920.1 identified by glimmer YP_002116921.1 'has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair' YP_002116922.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_002116923.1 identified by match to protein family HMM PF04220 YP_002116924.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002116925.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_002116926.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_002116927.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_002116928.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394 YP_002116929.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002116931.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002116933.1 identified by match to protein family HMM PF08443 YP_002116935.1 porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown YP_002116936.1 identified by match to protein family HMM TIGR00792 YP_002116937.1 identified by match to protein family HMM TIGR00792 YP_002116938.1 identified by match to protein family HMM PF01055 YP_002116939.1 identified by match to protein family HMM PF01263 YP_002116940.1 identified by match to protein family HMM PF07221 YP_002116941.1 identified by match to protein family HMM PF01791 YP_002116942.1 identified by match to protein family HMM PF03446 YP_002116943.1 identified by glimmer YP_002116944.1 identified by match to protein family HMM PF00294 YP_002116945.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002116946.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509 YP_002116947.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_002116948.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_002116949.1 identified by match to protein family HMM PF00583; match to protein family HMM PF09500; match to protein family HMM TIGR02447 YP_002116950.1 identified by match to protein family HMM PF01381 YP_002116952.1 identified by match to protein family HMM PF07859 YP_002116955.1 identified by match to protein family HMM PF01381 YP_002116956.1 required for the formation of active formate dehydrogenase YP_002116957.1 cytochrome b556(FDO) component; heme containing YP_002116958.1 identified by match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582 YP_002116959.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_002116961.1 identified by match to protein family HMM PF05437 YP_002116962.1 identified by match to protein family HMM PF03591 YP_002116963.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002116964.1 identified by match to protein family HMM PF05336; match to protein family HMM TIGR02625 YP_002116965.1 identified by match to protein family HMM PF00465; match to protein family HMM TIGR02638 YP_002116966.1 identified by match to protein family HMM PF00596; match to protein family HMM TIGR02624 YP_002116967.1 catalyzes the formation of L-rhamnulose from L-rhamnose YP_002116968.1 catalyzes the ATP-dependent phosphorylation of rhamnulose YP_002116969.1 activates the expression of the rhaBAD operon and rhaT gene YP_002116970.1 activates the expression of rhaRS in response to L-rhamnose YP_002116971.1 transports L-rhamnose and L-lyxose into the cell YP_002116973.1 identified by glimmer YP_002116974.1 identified by glimmer YP_002116975.1 identified by match to protein family HMM PF06178 YP_002116976.1 identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786 YP_002116977.1 identified by match to protein family HMM PF04290 YP_002116978.1 identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787 YP_002116979.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals YP_002116980.1 identified by match to protein family HMM PF03473; match to protein family HMM PF03475 YP_002116982.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_002116983.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_002116984.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates YP_002116985.1 'member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers' YP_002116986.1 'catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis' YP_002116987.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971 YP_002116988.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00792 YP_002116989.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least YP_002116990.1 identified by match to protein family HMM PF03747 YP_002116991.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002116992.1 identified by match to protein family HMM PF07883 YP_002116993.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_002116994.1 identified by match to protein family HMM PF04198 YP_002116995.1 identified by match to protein family HMM PF00005 YP_002116996.1 identified by match to protein family HMM PF02653 YP_002116997.1 identified by match to protein family HMM PF02653 YP_002116999.1 identified by match to protein family HMM PF01791 YP_002117000.1 identified by match to protein family HMM PF03992 YP_002117001.1 identified by match to protein family HMM PF00834 YP_002117002.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_002117003.1 identified by match to protein family HMM PF07305 YP_002117004.1 identified by match to protein family HMM PF05656 YP_002117005.1 identified by match to protein family HMM PF00175; match to protein family HMM PF00970 YP_002117006.1 'type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese' YP_002117007.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_002117008.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861 YP_002117009.1 identified by match to protein family HMM PF06005 YP_002117010.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_002117011.1 'catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate' YP_002117012.1 heat shock protein involved in degradation of misfolded proteins YP_002117013.1 heat shock protein involved in degradation of misfolded proteins YP_002117014.1 identified by match to protein family HMM PF05036; match to protein family HMM TIGR02223 YP_002117015.1 'negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins' YP_002117016.1 'binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity' YP_002117017.1 'RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome' YP_002117018.1 identified by match to protein family HMM PF09601; match to protein family HMM TIGR02117 YP_002117019.1 identified by match to protein family HMM PF05935 YP_002117020.1 identified by glimmer YP_002117021.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_002117022.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_002117023.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_002117026.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872 YP_002117027.1 'MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor' YP_002117028.1 identified by match to protein family HMM PF00141; match to protein family HMM TIGR00198 YP_002117029.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_002117030.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_002117031.1 identified by match to protein family HMM PF00165 YP_002117032.1 identified by match to protein family HMM PF00884 YP_002117033.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_002117034.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_002117035.1 'catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate' YP_002117036.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_002117037.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_002117038.1 'Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA' YP_002117039.1 catalyzes the conversion of NADPH to NADH YP_002117040.1 identified by match to protein family HMM PF07226 YP_002117041.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_002117042.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space YP_002117043.2 'converts L-glutamate to D-glutamate, a component of peptidoglycan' YP_002117045.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_002117046.1 'catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon' YP_002117047.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_002117049.1 'EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu' YP_002117050.1 'forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force' YP_002117051.1 Modulates Rho-dependent transcription termination YP_002117052.1 binds directly to 23S ribosomal RNA YP_002117053.1 'in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA' YP_002117054.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_002117055.1 'present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors' YP_002117056.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_002117057.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_002117060.1 'in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center' YP_002117061.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_002117062.1 'with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate' YP_002117063.1 identified by match to protein family HMM PF00899; match to protein family HMM PF05237 YP_002117064.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_002117065.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_002117066.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_002117067.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_002117068.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_002117069.1 'Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures' YP_002117070.1 identified by match to protein family HMM PF04222 YP_002117071.1 histone-like DNA-binding protein YP_002117072.1 identified by match to protein family HMM PF07356 YP_002117074.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002117075.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein YP_002117076.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_002117077.1 involved in de novo purine biosynthesis YP_002117079.1 identified by match to protein family HMM PF00583 YP_002117080.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_002117081.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_002117082.1 identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346 YP_002117084.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_002117085.1 identified by match to protein family HMM PF04266 YP_002117086.1 'regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase' YP_002117087.1 identified by glimmer YP_002117088.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_002117089.1 identified by match to protein family HMM PF02690; match to protein family HMM TIGR00704; match to protein family HMM TIGR01013 YP_002117090.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_002117092.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA YP_002117094.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002117095.1 identified by match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002117098.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_002117099.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_002117102.1 identified by match to protein family HMM PF06251 YP_002117103.1 identified by match to protein family HMM PF06082 YP_002117104.1 identified by match to protein family HMM PF06146 YP_002117105.1 xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter YP_002117106.1 with MalKFE is involved in the transport of maltose into the cell YP_002117107.1 with MalKGE is involved in maltose transport into the cell YP_002117108.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis YP_002117109.1 with malEFG is involved in import of maltose/maltodextrin YP_002117110.1 porin involved in the transport of maltose and maltodextrins YP_002117111.1 identified by match to protein family HMM PF07148 YP_002117112.1 catalyzes the formation of 4-hydroxybenzoate from chorismate YP_002117113.1 'catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway' YP_002117114.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_002117115.1 identified by match to protein family HMM PF01219 YP_002117116.1 Represses a number of genes involved in the response to DNA damage YP_002117117.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_002117119.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential YP_002117120.1 'Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB' YP_002117127.1 identified by glimmer YP_002117134.1 identified by match to protein family HMM PF05869; match to protein family HMM TIGR01712 YP_002117135.1 identified by match to protein family HMM PF01726 YP_002117136.1 identified by match to protein family HMM PF05866 YP_002117137.1 identified by match to protein family HMM PF04383 YP_002117138.1 identified by match to protein family HMM PF06914 YP_002117139.1 identified by match to protein family HMM PF03589 YP_002117140.1 identified by glimmer YP_002117141.1 identified by glimmer YP_002117143.1 identified by match to protein family HMM PF05449 YP_002117148.1 identified by match to protein family HMM PF05119; match to protein family HMM TIGR01558 YP_002117149.1 identified by match to protein family HMM PF03354 YP_002117150.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537 YP_002117151.1 identified by match to protein family HMM PF00574 YP_002117152.1 identified by match to protein family HMM PF05065; match to protein family HMM TIGR01554 YP_002117155.1 identified by match to protein family HMM TIGR01563 YP_002117159.1 identified by match to protein family HMM PF06274 YP_002117162.1 identified by match to protein family HMM TIGR01760 YP_002117164.1 identified by match to protein family HMM PF07157 YP_002117165.1 identified by match to protein family HMM PF06893 YP_002117166.1 identified by match to protein family HMM PF06890; match to protein family HMM TIGR01644 YP_002117167.1 identified by match to protein family HMM PF07409 YP_002117168.1 identified by match to protein family HMM PF04865 YP_002117171.1 identified by match to protein family HMM PF02413 YP_002117172.1 identified by match to protein family HMM PF05364; match to protein family HMM PF07487 YP_002117173.1 identified by glimmer YP_002117174.1 identified by match to protein family HMM PF02796 YP_002117175.1 identified by match to protein family HMM PF06183 YP_002117176.1 identified by match to protein family HMM PF00589 YP_002117177.1 identified by match to protein family HMM PF01207; match to protein family HMM TIGR00742 YP_002117178.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002117179.1 unwinds double stranded DNA YP_002117180.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_002117181.1 identified by glimmer YP_002117182.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002117183.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity YP_002117184.1 identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149 YP_002117185.1 identified by match to protein family HMM PF04237 YP_002117188.1 'The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate' YP_002117189.1 binds to single stranded DNA and PriA helcase facilitate replication restart YP_002117190.1 identified by glimmer YP_002117191.1 identified by glimmer YP_002117194.1 identified by match to protein family HMM PF02321 YP_002117196.1 identified by match to protein family HMM PF00005 YP_002117197.1 identified by match to protein family HMM PF00563 YP_002117198.1 regulates genes involved in response to oxidative stress YP_002117199.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR01950 YP_002117200.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_002117201.1 identified by glimmer YP_002117202.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_002117203.1 identified by glimmer YP_002117204.1 identified by match to protein family HMM PF00999; match to protein family HMM TIGR00831 YP_002117205.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002117206.2 identified by match to protein family HMM PF03788 YP_002117207.1 identified by match to protein family HMM PF04172 YP_002117208.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_002117209.1 identified by match to protein family HMM PF04341 YP_002117210.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_002117211.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_002117212.1 'part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia' YP_002117213.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409; match to protein family HMM TIGR03149 YP_002117214.1 identified by match to protein family HMM PF03916; match to protein family HMM TIGR03148 YP_002117215.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552 YP_002117216.1 identified by match to protein family HMM PF03918; match to protein family HMM TIGR03147 YP_002117217.1 identified by match to protein family HMM PF07719 YP_002117219.1 'carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system' YP_002117220.1 identified by match to protein family HMM PF08238 YP_002117221.1 identified by match to protein family HMM PF05118 YP_002117222.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role YP_002117223.1 identified by match to protein family HMM PF00903; match to protein family HMM PF06983 YP_002117224.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686 YP_002117225.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM PF08946; match to protein family HMM TIGR00883 YP_002117226.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002117227.1 response regulator in two-component regulatory system with BasS YP_002117228.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_002117229.1 identified by match to protein family HMM PF00324 YP_002117230.1 identified by match to protein family HMM PF00165 YP_002117231.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_002117232.1 identified by match to protein family HMM PF00165 YP_002117233.1 identified by match to protein family HMM PF02056 YP_002117234.1 identified by match to protein family HMM TIGR00792 YP_002117235.1 identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_002117236.1 'functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters' YP_002117238.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration YP_002117239.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_002117240.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_002117241.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_002117242.1 identified by match to protein family HMM PF04976 YP_002117243.1 identified by match to protein family HMM PF09362 YP_002117244.1 identified by glimmer YP_002117245.1 identified by match to protein family HMM PF06977 YP_002117246.1 identified by glimmer YP_002117247.1 identified by match to protein family HMM PF00196 YP_002117248.1 identified by match to protein family HMM PF00165 YP_002117249.1 identified by glimmer YP_002117250.1 identified by match to protein family HMM PF08681 YP_002117251.1 identified by match to protein family HMM PF00583 YP_002117252.1 identified by glimmer YP_002117253.1 identified by glimmer YP_002117254.1 identified by match to protein family HMM PF03333 YP_002117255.1 identified by match to protein family HMM PF00419 YP_002117256.1 identified by match to protein family HMM PF00577 YP_002117257.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002117260.1 identified by match to protein family HMM PF02432 YP_002117261.1 identified by match to protein family HMM PF02432 YP_002117263.1 identified by match to protein family HMM PF04703 YP_002117264.1 identified by glimmer YP_002117265.1 identified by match to protein family HMM PF06977 YP_002117266.1 identified by match to protein family HMM PF01569 YP_002117267.1 identified by glimmer YP_002117268.1 identified by match to protein family HMM PF00440 YP_002117269.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_002117270.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals YP_002117271.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_002117272.1 catalyzes the formation of fumarate from aspartate YP_002117273.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_002117274.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_002117275.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_002117276.1 '60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth' YP_002117279.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR00238 YP_002117280.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_002117281.1 identified by match to protein family HMM PF08085 YP_002117282.1 identified by match to protein family HMM PF00196 YP_002117284.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_002117285.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_002117286.1 'part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB' YP_002117287.1 'part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB' YP_002117288.1 'part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB' YP_002117289.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002117290.1 identified by match to protein family HMM PF00324 YP_002117291.1 identified by match to protein family HMM PF00924 YP_002117292.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_002117293.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_002117294.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_002117295.1 identified by match to protein family HMM PF00497 YP_002117296.1 identified by match to protein family HMM PF08331; match to protein family HMM TIGR00276 YP_002117297.1 identified by match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197 YP_002117298.1 possibly involved in cell wall synthesis YP_002117299.1 identified by match to protein family HMM PF01520 YP_002117300.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_002117301.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_002117302.1 Stimulates the elongation of poly(A) tails YP_002117303.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_002117304.1 with HflC inhibits proteolysis of lambda cII protein by FtsH YP_002117305.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_002117307.1 'catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis' YP_002117308.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_002117309.1 '3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs' YP_002117310.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_002117312.1 identified by glimmer YP_002117314.1 identified by match to protein family HMM PF03994 YP_002117315.1 identified by match to protein family HMM PF06693 YP_002117316.1 identified by match to protein family HMM PF03738 YP_002117317.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA YP_002117318.1 identified by match to protein family HMM PF07338 YP_002117319.1 'in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility' YP_002117320.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_002117321.1 negative regulator of ulaG and ulaABCDEF YP_002117323.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002117324.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_002117325.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_002117326.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization YP_002117327.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway YP_002117328.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_002117329.1 identified by match to protein family HMM PF07274 YP_002117330.1 identified by match to protein family HMM PF07338 YP_002117331.1 'binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21' YP_002117332.1 binds single-stranded DNA at the primosome assembly site YP_002117333.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_002117334.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_002117335.1 identified by match to protein family HMM PF00892 YP_002117336.1 identified by match to protein family HMM PF04225; match to protein family HMM PF08525 YP_002117337.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_002117338.1 'involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine' YP_002117339.1 Involved in anaerobic NO protection and iron metabolism YP_002117340.1 identified by match to protein family HMM PF00892 YP_002117341.1 identified by match to protein family HMM PF01073; match to protein family HMM PF02254; match to protein family HMM PF05368; match to protein family HMM PF07993 YP_002117342.1 'periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate' YP_002117343.1 'catalyzes the formation of AMP from adenosine-3',5'-bisphosphate' YP_002117344.1 identified by match to protein family HMM PF09695; match to protein family HMM TIGR01626 YP_002117345.1 identified by match to protein family HMM PF06526 YP_002117346.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_002117347.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_002117348.1 identified by glimmer YP_002117349.1 identified by match to protein family HMM PF01103; match to protein family HMM PF07244 YP_002117350.1 identified by match to protein family HMM PF04357 YP_002117351.1 identified by match to protein family HMM PF06094 YP_002117352.1 identified by match to protein family HMM PF07690 YP_002117353.1 identified by match to protein family HMM PF01979 YP_002117354.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_002117355.1 'catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate' YP_002117356.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01081 YP_002117357.1 identified by match to protein family HMM PF04751 YP_002117358.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_002117359.1 identified by match to protein family HMM PF07361 YP_002117360.1 identified by match to protein family HMM PF00874; match to protein family HMM TIGR03582 YP_002117361.1 identified by match to protein family HMM TIGR03577 YP_002117362.1 identified by match to protein family HMM TIGR03578 YP_002117363.1 identified by match to protein family HMM TIGR03580 YP_002117364.1 identified by match to protein family HMM TIGR03579 YP_002117365.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_002117366.1 identified by match to protein family HMM PF01212; match to protein family HMM PF03841; match to protein family HMM TIGR01437 YP_002117367.1 identified by match to protein family HMM PF07071; match to protein family HMM TIGR03581 YP_002117368.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279 YP_002117369.1 Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor YP_002117370.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385 YP_002117371.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_002117372.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_002117374.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403 YP_002117375.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002117376.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon YP_002117377.2 P-type ATPase involved in magnesium influx YP_002117378.1 identified by match to protein family HMM PF01527 YP_002117379.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004 YP_002117380.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_002117381.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_002117382.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863 YP_002117383.1 identified by glimmer YP_002117384.1 identified by match to protein family HMM PF03606 YP_002117386.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_002117387.1 catalyzes the degradation of arginine to citruline and ammonia YP_002117389.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_002117390.1 'catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.' YP_002117391.1 identified by match to protein family HMM PF06877 YP_002117392.1 identified by match to protein family HMM PF06175 YP_002117394.1 identified by match to protein family HMM PF00583 YP_002117395.1 identified by match to protein family HMM PF05987 YP_002117396.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_002117397.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_002117398.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_002117399.1 identified by match to protein family HMM PF03739 YP_002117400.1 identified by match to protein family HMM PF03739 YP_002117401.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002117402.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_002117403.1 'Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate' YP_002117404.1 NAD-binding YP_002117405.1 identified by match to protein family HMM PF01202; match to protein family HMM TIGR01313 YP_002117406.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002117408.1 identified by match to protein family HMM PF07362 YP_002117409.1 identified by match to protein family HMM PF01845 YP_002117410.1 identified by match to protein family HMM PF00614 YP_002117411.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_002117412.1 identified by match to protein family HMM PF09019; match to protein family HMM PF09217 YP_002117414.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_002117415.1 identified by glimmer YP_002117416.1 identified by match to protein family HMM PF05175; match to protein family HMM PF07021; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002117418.1 identified by glimmer YP_002117419.1 identified by match to protein family HMM PF06353 YP_002117421.1 identified by glimmer YP_002117422.1 identified by glimmer YP_002117423.1 identified by match to protein family HMM PF03625 YP_002117424.1 identified by match to protein family HMM PF01738 YP_002117425.1 regulates the expression of uxuBA YP_002117426.1 'catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA' YP_002117428.2 identified by match to protein family HMM PF05638 YP_002117429.1 identified by glimmer YP_002117430.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035 YP_002117431.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002117432.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR01975 YP_002117433.1 identified by match to protein family HMM PF07670 YP_002117434.1 identified by match to protein family HMM PF07670 YP_002117435.1 identified by glimmer YP_002117436.1 identified by match to protein family HMM PF06779; match to protein family HMM PF07690 YP_002117437.1 identified by match to protein family HMM PF04286 YP_002117438.1 identified by match to protein family HMM PF07690 YP_002117439.1 identified by glimmer YP_002117440.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_002117441.1 identified by glimmer YP_002117442.1 identified by match to protein family HMM PF00171 YP_002117443.1 identified by match to protein family HMM PF06568 YP_002117445.1 identified by match to protein family HMM PF01810 YP_002117446.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311 YP_002117447.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_002117448.1 identified by match to protein family HMM PF04328 YP_002117449.1 identified by match to protein family HMM PF02554 YP_002117450.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_002117452.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00874 YP_002117453.1 identified by match to protein family HMM PF03610 YP_002117454.1 identified by match to protein family HMM PF03830 YP_002117455.1 identified by match to protein family HMM PF03609 YP_002117456.1 identified by match to protein family HMM PF03613 YP_002117457.1 identified by match to protein family HMM PF01380 YP_002117458.1 identified by match to protein family HMM PF01380 YP_002117459.1 catalyzes the transfer of phosphoglycerol to the glucan backbone YP_002117461.1 acts to load the DnaB helicase onto the initiation site during DNA replication YP_002117462.1 'This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'' YP_002117464.1 identified by match to protein family HMM PF06738 YP_002117465.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin YP_002117466.1 identified by match to protein family HMM PF04073 YP_002117467.1 identified by match to protein family HMM PF06276 YP_002117468.2 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002117469.1 identified by match to protein family HMM PF07256 YP_002117470.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_002117471.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_002117472.2 identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575 YP_002117473.1 'manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily' YP_002117474.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_002117475.1 identified by glimmer YP_002117476.1 identified by match to protein family HMM PF04972 YP_002117477.1 identified by glimmer YP_002117478.1 identified by match to protein family HMM PF01734 YP_002117479.1 identified by match to protein family HMM PF01026 YP_002117480.1 identified by match to protein family HMM PF04055 YP_002117482.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_002117483.1 'Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate' YP_002117484.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_002117485.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_002117487.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins YP_002117489.1 catalyzes the formation of serine from O-phosphoserine YP_002117490.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_002117491.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_002117492.1 'ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence' YP_002117493.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_002117494.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_002117495.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_002117496.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_002117497.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_002117498.1 identified by match to protein family HMM PF05981 YP_002117499.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation YP_002117500.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation YP_002117501.1 identified by match to protein family HMM PF06123 YP_002117502.1 identified by match to protein family HMM PF00419 YP_002117503.1 identified by match to protein family HMM PF00419 YP_002117504.2 identified by match to protein family HMM PF00577 YP_002117505.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002117506.1 identified by match to protein family HMM PF00419 YP_002117508.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002117509.1 member of the SPOUT superfamily of methyltransferases