-- dump date 20050316_181731 -- class Genbank::CDS -- table cds_note -- id note 16805108 Pfam match to entry PF03011 PFEMP, E-value 6e-68 Similar to Plasmodium falciparum pfemp1 variant 2 of strain mc mcvar-2 pfemp1 SWALL:Q25734 (EMBL:U27339) (1729 aa) fasta scores: E(): 6.4e-132, 40% id in 1805 aa 16805109 Similarity to other P.falciparum rifins. Member of a multi-gene family; Pfam match to entry PF02009 Rifin_STEVOR, Rifinstevor family, score 598.60, E-value 3.8e-176 36329000003 pseudo-VAR gene 16805110 Similarity to other P.falciparum stevors. Member of a multi-gene family; possible signal peptide, but not predicted using SignalP 2.0 HMM Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 384.80, E-value 1.1e-112 16805111 Similarity to other P.falciparum rifins. Member of a multi-gene family; Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.947, signal anchor probability 0.034) with cleavage site probability 0.331 between residues 24 and 25 Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 463.50, E-value 6.4e-136 16805112 Similarity to other P.falciparum rifins. Member of a multi-gene family; Signal peptide predicted for PFC0035w, MAL3P8.6 by SignalP 2.0 (Signal peptide probabilty 0.900, signal anchor probability 0.006) with cleavage site probability 0.425 between residues 29 and 30, predicted protein longer at N-terminal end than other rifins so start could be at met6 depending on where start of transcription is Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 542.00, E-value 4e-159 16805113 Similarity to other P.falciparum rifins. Member of a multi-gene family; predicted signal sequence but not predicted using SignalP 2.0 HMM Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 62.20, E-value 1.3e-17 16805114 Similarity: at 5' end to stevors eg CAB39117 MAL3P8.4 (296 aa) fasta score: 42.4% identity in 144 aa overlap). Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.646, signal anchor probability 0.131) with cleavage site probability 0.302 between residues 21 and 22; revised by adding small 3' exon at first potential acceptor, other possible acceptors exist downstream 16805115 Similarity to long-chain-fatty-acid-CoA ligases. eg AAD53966 P. falciparum fatty acyl coenzyme A synthetase-1 (820 aa), fasta scores: opt: 4295, E(): 0, 79.0% identity in 821 aa overlap; contains possible signal sequence but not predicted by SignalP 2.0 HMM Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme, score 173.10, E-value 4.7e-48 16805116 Contains predicted signal and transmembrane region; signal sequence not predicted by SignalP 2.0, potential for splicing at 3' 16805117 Similarity to protein kinases; alternatives exist for 5' donor 2 weak Pfam matches to entry PF00069 pkinase, Protein kinase domain 16805118 Similarity to alpha/beta hydrolases and esterases. Synechocystis sp. (SW:PRXC_SYNY3) peroxidase BLAST Score: 145, sum P(1) = 1.0e-07; contains possible signal sequence, predicted using hexExon, Signal anchor predicted by SignalP 2.0 (Signal peptide probabilty 0.004, signal anchor probability 0.995) with cleavage site probability 0.002 between residues 31 and 32 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold, score 33.90, E-value 3.8e-06 16805119 Hypothetical protein, len: 244 aa; contains possible signal sequence but not predicted by SignalP 2.0 HMM, probably spliced at 3' - added 3' exon but alternatives exist 16805121 5' exon may not be real and could start at e.g. Met in 2nd exon 16805122 Revised: new 5' donor, longer at 5' than in P. vivax TR:Q962M9 (EMBL:AY003872) so could start at second Met 16805123 Possibly spliced at 3' end Similar to Plasmodium vivax pv1h14030_p pv1h14030W SWALL:AAF99452 (EMBL:AY003872) (236 aa) fasta scores: E(): 6.3e-20, 30.63% id in 235 aa 16805124 Splicing possible at 3' end Similar to Plasmodium vivax pv1h14035_p pv1h14035C SWALL:AAF99453 (EMBL:AY003872) (374 aa) fasta scores: E(): 8.2e-57, 66.16% id in 399 aa 16805125 Revised prediction: added 3' exon, similar to P. vivax PV1H14040C, 77.946% identity in 594 aa overlap several Pfam matches to entry PF00400 WD40, WD domain, G-beta repeat, lowest score 32.40, E-value 1e-05 Similar to Plasmodium vivax pv1h14040_p pv1h14040C SWALL:Q962M6 (EMBL:AY003872) blast scores: E(): 0.0, score: 421 63% id, and to Rattus norvegicus pleiotropic regulator 1 plrg1 SWALL:Q9WUC8 (EMBL:AF128241) blast scores: E(): e-107, score: 995 52% id, and to Schizosaccharomyces pombe pre-mrna splicing protein prp5 prp5 or cwf1 or spbp22h7.07 or pi024 SWALL:PRP5_SCHPO (SWALL:O13615) blast scores: E(): e-104, score: 968 54% id 16805126 Three regions of significant similarity with serine kinases. Human serine kinase (TR:Q12890) BLAST score: 967 Sum P(3) = 1.0e-84, predicted using hexExon, similar to P. vivax PV1H14045W, 44.694% identity in 1423 aa overlap 2 Pfam matches to entry PF00069 pkinase, Protein kinase domain, E-value 4.4e-22 and 9.6e-14 16805127 Possible signal sequence present, revised exon 6 acceptor, Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.966, signal anchor probability 0.019) with cleavage site probability 0.748 between residues 24 and 25 Similar to Plasmodium falciparum cytoadherence linked asexual protein clag9 SWALL:Q9NAV4 (EMBL:AF286130) (1339 aa) fasta scores: E(): 2e-125, 42% id in 1314 aa 36329000022 Pseudo-VAR gene:heavily frame-shifted genomic region with patchy similarity to PfEMP1 16805128 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.633, signal anchor probability 0.158) with cleavage site probability 0.331 between residues 24 and 25 Similar to Plasmodium yoelii Pyrhoph1A pyrhoph1A SWALL:Q95NI9 (EMBL:AB060734) (1292 aa) fasta scores: E(): 9.6e-160, 39.61% id in 1310 aa, and to Plasmodium chabaudi cytoadherence linked asexual protein-like protein SWALL:Q8WRY3 (EMBL:AF387740) (1296 aa) fasta scores: E(): 2.5e-154, 38.03% id in 1320 aa 16805129 Three regions of moderate similarity to ABC transporters, especially those from compositionally biased genomes such as Dictyostelium and P.falciparum HB3 multidrug resistance gene pfmdr2 (TR:Q08667). BLAST score: 60 Sum P(3) = 1.6e-43; Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.702, signal anchor probability 0.124) with cleavage site probability 0.426 between residues 20 and 21, similar to P. vivax PV1H14050W, 56.529% identity in 1279 aa overlap 2 Pfam matches to entry PF00005 ABC_tran, ABC transporter, E-value 7e-22 and 3.3e-17 16805130 Contains region similar to C. elegans BAA92262 klp17, kinesin like protein (605 aa) fasta scores: opt: 160, E(): 0.002, 42.2% identity in 64 aa overlap Similar to Plasmodium vivax pv1h14055_p pv1h14055C SWALL:Q962M3 (EMBL:AY003872) (152 aa) fasta scores: E(): 7.9e-40, 73.79% id in 145 aa 16805131 Possibly spliced at 3' Similar to Plasmodium vivax pv1h14060_p pv1h14060C SWALL:AAF99458 (EMBL:AY003872) (462 aa) fasta scores: E(): 1.1e-39, 53.5% id in 456 aa 16805132 Similar to Plasmodium vivax pv1h14065_p pv1h14065C SWALL:AAF99459 (EMBL:AY003872) (1247 aa) fasta scores: E(): 0, 91.29% id in 1264 aa, and to Arabidopsis thaliana exportin 1b xpo1B SWALL:CAC39223 (EMBL:AJ277542) (1076 aa) fasta scores: E(): 9.9e-28, 28.7% id in 1261 aa, and to Homo sapiens Crm1 protein crm1 SWALL:O14980 (EMBL:D89729) (1071 aa) fasta scores: E(): 6e-27, 28.18% id in 1242 aa 16805133 Similarity to a number of eukaryotic N-ethylmaleimide sensitive fusion proteins (NSFs). Human NSF (SW:NSF_MOUSE). BLAST score: 1577, sum P(2) = 2.4e-142, similar to P. vivax PV1H14070C, 80.435% identity (80.745% ungapped) in 782 aa overlap Pfam match to entry PF00004 AAA, ATPase family associated with various cellular activities (AAA), score 265.50, E-value 7e-76 16805134 Similar to Plasmodium vivax pv1h14075_p pv1h14075C SWALL:AAF99461 (EMBL:AY003872) (1165 aa) fasta scores: E(): 9.2e-13, 33.31% id in 1456 aa 23957710 Revised prediction with different 5' exon and additional 3' exon, REVISED 3' exon for a different one by comparison with P. yoelii, P. knowlesi and P. vivax Similar to Plasmodium vivax pv1h14080_p pv1h14080W SWALL:AAF99462 (EMBL:AY003872) (1080 aa) fasta scores: E(): 6.4e-104, 53.22% id in 1133 aa, and to Arabidopsis thaliana gb|aaf23287.1 SWALL:Q9FMN2 (EMBL:AB008264) (930 aa) fasta scores: E(): 9.4e-32, 31.32% id in 597 aa 16805136 First exon unsure Pfam match to entry PF01192 RNA_pol_K, RNA polymerases K / 14 to 18 kDa subunit, score 75.10, E-value 1.5e-18 Similar to Plasmodium vivax pv1h14085_p pv1h14085C SWALL:AAF99463 (EMBL:AY003872) (157 aa) fasta scores: E(): 1.6e-46, 84.41% id in 154 aa, and to Drosophila melanogaster DNA-directed RNA polymerase ii 14.4 kDa polypeptide rpii18 or rpabc14 or cg1163 SWALL:RPB6_DROME (SWALL:Q24320) (131 aa) fasta scores: E(): 1.2e-05, 40.41% id in 146 aa, and to Rattus norvegicus DNA-directed RNA polymerase ii 14.4 kDa polypeptide polr2F SWALL:RPB6_RAT (SWALL:O88828) (127 aa) fasta scores: E(): 3.2e-05, 44.44% id in 144 aa 23957711 Revised: revised to 8 exon structure, revised: donor for exon 7 4 weak Pfam matches to entry PF00023 ank, Ank repeat; Pfam match to entry PF01529 zf-DHHC, DHHC zinc finger domain, score 66.70, E-value 4.8e-16 Similar to Plasmodium vivax pv1h14090_p pv1h14090W SWALL:AAF99464 (EMBL:AY003872) (611 aa) fasta scores: E(): 5.6e-172, 71.94% id in 613 aa, and to Mus musculus 5033406l14riK protein 5033406l14riK SWALL:Q9D3Q8 (EMBL:AK017158) (368 aa) fasta scores: E(): 1.7e-09, 24.87% id in 197 aa, and to Rattus norvegicus small rec sreC SWALL:Q9JKR5 (EMBL:AF228917) (366 aa) fasta scores: E(): 8.4e-09, 27.95% id in 161 aa 23957712 Revised: original entry split into PFC0165w and PFC0166w Similar to Plasmodium vivax pv1h14095_p pv1h14095W SWALL:Q962L5 (EMBL:AY003872) blast scores: E(): 0.0, score: 2249 43% id, and to Plasmodium falciparum thioredoxin-like redox-active protein freD SWALL:Q9NC62 (EMBL:AF234633) (179 aa) fasta scores: E(): 7.5e-47, 99.42% id in 175 aa 23957713 Revised: split original spliced gene PFC0165w into PFC0165w and PFC0166w, fasta; Plasmodium falciparum; thioredoxin-like redox-active protein; freD; length 179 aa; id=100%; ungapped id=100%; E()=2.1e-69; 179 aa overlap; query 1-179 aa; subject 1-179 aa; fasta; TR:AAF99466 (EMBL:AY003872); Plasmodium vivax; pv1h14100_p; pv1h14100W; length 179 aa; id=65.92%; ungapped id=67.42%; E()=1.5e-46; 179 aa overlap; query 1-177 aa; subject 1-177 aa 16805139 Similarity to lipoamide acyltransferases. eg C.elegans lipoamide acyltransferase (WP:ZK669.4) BLAST Score: 582, sum P(1) = 9.2e-57; 33% identity in 430 aa overlap; similarity to P. vivax PV1H14105C, 59.908% identity (61.611% ungapped) in 434 aa overlap Pfam match to entry PF00198 2-oxoacid_dh, 2-oxo acid dehydrogenases acyltransferase (catalytic domain), score 140.90, E-value 2.2e-38; Pfam match to entry PF00364 biotin_lipoyl, Biotin-requiring enzyme, score 46.20, E-value 7.4e-10 Similar to Arabidopsis thaliana branched chain alpha-keto acid dehydrogenase e2 subunit din3 SWALL:Q9M724 (EMBL:AF145451) (483 aa) fasta scores: E(): 3.3e-28, 31.35% id in 421 aa, and to Thermoplasma volcanium pyruvate dehydrogenase e2 / dihydrolipoamide acetyltransferase tv0099 or tvg0103933 SWALL:Q97CK2 (EMBL:AP000991) (400 aa) fasta scores: E(): 5.6e-21, 28.16% id in 419 aa 16805140 Similarity with a number of unknown proteins from model organisms. eg C.elegans hypothetical protein (TR:O01963) BLAST Score: 361, sum P(1) = 4.0e-47, 35% identity in 227 aa overlap; similarity to P. vivax PV1H14110W, 42.516% identity (45.331% ungapped) in 628 aa overlap Similar to Drosophila melanogaster ariadne-2 protein ari-2 or ari2 or triad1 or cg5709 SWALL:ARI2_DROME (SWALL:O76924) (509 aa) fasta scores: E(): 6.3e-23, 23.85% id in 545 aa, and to Homo sapiens ariadne-1 protein homolog arih1 or ari or ubch7bP SWALL:ARI1_HUMAN (SWALL:Q9Y4X5) (557 aa) fasta scores: E(): 1.1e-21, 25.3% id in 498 aa 23957714 Revised gene prediction: deleted last exon by comparison with P. knowlesi, P. vivax, P. yoelii; Signal peptide predicted for PFC0176c by SignalP 2.0 HMM (Signal peptide probabilty 0.843, signal anchor probability 0.094) with cleavage site probability 0.776 between residues 22 and 23 Similar to Plasmodium vivax pv1h14115_p pv1h14115C SWALL:AAF99469 (EMBL:AY003872) (195 aa) fasta scores: E(): 2.6e-38, 53.06% id in 196 aa 23957715 Revised prediction: added a 4th intron by similarity with py and pk, similar to P. vivax PV1H14120C, 48.959% identity (54.982% ungapped) in 913 aa overlap Similar to Toxoplasma gondii membrane skeletal protein Imc1 imc1 SWALL:AAK39634 (EMBL:AY032678) (609 aa) fasta scores: E(): 2.1e-40, 49.32% id in 446 aa 16805142 Similar to Plasmodium vivax pv1h14125_p pv1h14125W SWALL:AAF99471 (EMBL:AY003872) (529 aa) fasta scores: E(): 8.6e-93, 66.81% id in 443 aa 23957716 Similarity to PAST proteins from H.sapiens and D.melanogaster. H.sapiens HPAST protein (TR:O14611) BLAST Score: 1245, sum P(1) = 5.1e-127, 47% identity in 518 aa overlap, predicted using hexExon, revised: to most upstream initiation codon but similarity with P. vivax and P. yoelii suggests met9 as initiation codon; similar to P. vivax PV1H14130C, 90.840% identity (90.840% ungapped) in 524 aa overlap 23957717 hypothetical protein, len: 88 aa, GC peaks indicate possible coding in this region but difficult to come up with a compelling prediction, unable to find homologue in other plasmodium spp. 23957718 The original predicted intron was suspiciously small, it could signify a possible frameshift or different splice site(s) - the potential acceptor has been changed to one further downstream Similar to Plasmodium vivax pv1h14135_p pv1h14135W SWALL:AAF99473 (EMBL:AY003872) (1245 aa) fasta scores: E(): 5.3e-37, 25.47% id in 1307 aa 16805145 Similar to Plasmodium vivax pv1h14140_p pv1h14140W TR:AAF99474 (EMBL:AY003872) (103 aa) fasta scores: E(): 1.8e-37, 97.11% id in 104 aa Similarity to ribosomal protein L44. S.cerevisiae 60S ribosomal protein L44 (SW:RL44_YEAST) BLAST Score: 385, sum P(1) = 6.9e-36; 68% identity in 103 aa overlap; similar to Plasmodium vivax pv1h14140_p pv1h14140W TR:AAF99474 (EMBL:AY003872) (103 aa) fasta scores: E(): 1.8e-37, 97.11% id in 104 aa 60S Ribosomal protein L44, putative 16805146 Similarity to a number of conserved hypothetical proteins, eg N. meningitidis AAF41186 (103 aa), fasta scores opt: 345, E(): 1.1e-15, 49.0% identity in 96 aa overlap, identified as 1-cys-glutaredoxin-like protein-1 glp-1 TR:AAK00581 (EMBL:AY014839); similar to Plasmodium vivax pv1h14145_p pv1h14145C TR:AAF99475 (EMBL:AY003872) (168 aa) fasta scores: E(): 5.1e-40, 67.25% id in 171 aa 23957719 Similarity to many Plasmodium CS proteins, signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.996, signal anchor probability 0.000) with cleavage site probability 0.495 between residues 20 and 21, revised to include upstream initiation codon; Pfam match to entry PF00090 tsp_1, Thrombospondin type 1 domain 23957720 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.788, signal anchor probability 0.191) with cleavage site probability 0.642 between residues 21 and 22 23957721 Revised by removing upstream splicing and included upstream inframe initiation codon; similar to Plasmodium vivax pv1h14160_p pv1h14160W TR:AAF99478 (EMBL:AY003872) (1092 aa) fasta scores: E(): 7e-08, 24.52% id in 1476 aa 23957722 Similar to Plasmodium vivax pv1h14165_p pv1h14165C SWALL:AAF99479 (EMBL:AY003872) (171 aa) fasta scores: E(): 4.3e-31, 63.03% id in 165 aa 23957723 Similarity to elongation factor TS. Aquifex elongation factor TS (SW:EFTS_AQUAE) BLAST Score: 161, sum P(2) = 4.9e-19, 30% identity in 133 aa overlap, Pfam match to entry PF00889 EF_TS, Elongation factor TS, E()=2e-25; revised: added 3' exon; signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.980, signal anchor probability 0.014) with cleavage site probability 0.480 between residues 18 and 19; similar to P. vivax PV1H14170c, 50.656% identity (54.986% ungapped) in 381 aa overlap 16805151 Possibilities exist for splicing at 3' end Similar to Plasmodium vivax pv1h14175_p pv1h14175C SWALL:AAF99481 (EMBL:AY003872) (3025 aa) fasta scores: E(): 1.4e-29, 26.38% id in 3244 aa 23957724 Revised: deleted splicing at 5' end and start at downstream inframe initiation codon Similar to Plasmodium vivax pv1h14180_p pv1h14180W SWALL:AAF99482 (EMBL:AY003872) (1011 aa) fasta scores: E(): 7e-40, 29.57% id in 984 aa 23957725 Revised: added two exons at 3' but could be more, included extra met at 5' Similar to Plasmodium vivax pv1h14185_p pv1h15185C SWALL:AAF99483 (EMBL:AY003872) (846 aa) fasta scores: E(): 3.1e-62, 56.86% id in 874 aa 23957726 Revised: shortened first exon at 5' but extended at 3' and deleted exon 2 by similarity with P.yoelii and P. knowlesi, unsure but deleted last exon Similar to Plasmodium vivax pv1h14190_p pv1h14190W SWALL:AAF99484 (EMBL:AY003872) (145 aa) fasta scores: E(): 5.2e-45, 83.44% id in 145 aa 16805154 Similar to Plasmodium vivax pv1h14195_p pv1h14195C SWALL:AAF99485 (EMBL:AY003872) (3676 aa) fasta scores: E(): 4.4e-60, 43.24% id in 4172 aa 23957727 AP endonuclease, len: 639 aa; Similarity to nucleases. B.subtilus exodeoxyribonuclease (SW:EXOA_BACSU) BLAST Score: 200, sum P(3) = 1.8e-25; 32% identity in 186 aa overlap Revised: deleted 5' exon and extended to upstream initiation codon; similar to Plasmodium vivax PV1H14200C, 57.955% identity (63.275% ungapped) in 440 aa overlap (200-615:93-519) Pfam match to entry PF01260 AP_endonucleas1, AP endonuclease family 1, score 321.40, E-value 7.5e-97 16805156 Similarity to ubiquitin-conjugating enzyme E2. S.cerevisiae hypothetical protein YGL087C (YGI7_YEAST) BLAST Score: 378, sum P(1) = 3.8e-35; 52% identity in 134 aa overlap; similar to Plasmodium vivax PV1H14205C, 91.608% identity (94.245% ungapped) in 143 aa overlap (1-139:1-143) Pfam match to entry PF00179 UQ_con, Ubiquitin-conjugating enzyme, score -3.80, E-value 5.8e-06 23957728 Revised: removed 5' exon Similar to Plasmodium vivax pv1h14210_p pv1h14210W SWALL:AAF99488 (EMBL:AY003872) (894 aa) fasta scores: E(): 2.4e-41, 41.91% id in 1119 aa 23957729 Revised: new gene prediction Similar to Plasmodium vivax pv1h14215_p pv1h14215C SWALL:AAF99489 (EMBL:AY003872) (177 aa) fasta scores: E(): 1.1e-09, 34.09% id in 176 aa 23957730 Revised: removed splicing Similar to Plasmodium vivax pv1h14220_p pv1h14220C SWALL:AAF99490 (EMBL:AY003872) (137 aa) fasta scores: E(): 3.3e-43, 75.37% id in 134 aa 23957731 Revised: added 3' exon Similar to Plasmodium vivax pv1h14225_p pv1h14225C SWALL:AAF99491 (EMBL:AY003872) (160 aa) fasta scores: E(): 7.5e-25, 63.75% id in 149 aa 23957732 Splicing confirmed in P. yoelii 23957733 Similar to eg GLRX_RABIT glutaredoxin (106 aa), fasta scores: opt: 269, E(): 2.1e-12, 38.6% identity in 101 aa overlap, revised: new gene prediction; identified as grx1, glutaredoxin 1 in AAK91589, gene model confirmed in p_knowlesi and P. yoelii Pfam match to entry PF00462 glutaredoxin, Glutaredoxin, score 50.40, E-value 3.9e-11 16805160 Similarity to glycerol-3-phosphate dehydrogenases. C.elegans glycerol-3-phosphate dehydrogenase (TR:P90795) BLAST Score: 846, sum P(2) = 1.6e-109; 46% identity in 364 aa overlap Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase, score 242.30, E-value 6.9e-69 16805161 conserved in P. knowlesi and P. yoelii 23957734 Revised: new gene prediction; CDS confirmed in P. knowlesi and P. yoelii 23957735 Revised: new gene prediction; CDS confirmed in P. knowlesi and P. yoelii 23957736 Similarity to T-complex proteins beta subunits. C.elegans T-complex protein beta subunit (SW:TCPB_CAEEL) BLAST Score: 1527, sum P(1) = 6.7e-157, 57% identity in 527 aa overlap, Pfam match to entry PF00118 cpn60_TCP1, TCP-1/cpn60 chaperonin family, revised: added splicing at 3' end, removed 5' exon, revised: changed to being unspliced in coding region, probably spliced 5' UTR Pfam match to entry PF00118 cpn60_TCP1, TCP-1/cpn60 chaperonin family, score 518.70, E-value 4.2e-152 Similar to Caenorhabditis elegans t-complex protein 1, beta subunit cct-2 or cctB SWALL:TCPB_CAEEL (SWALL:P47207) (529 aa) fasta scores: E(): 4.3e-112, 57.08% id in 529 aa 16805163 Similarity to ribosomal S23 proteins. C.elegans 40S ribosomal protein S23 (WP:F28D1.7) BLAST Score:609, sum P(1) = 1.3e-59; 78% identity in 142 aa overlap Pfam match to entry PF00164 Ribosomal_S12, Ribosomal protein S12, score 270.30, E-value 2.6e-77 16805164 Similarity to 40S ribosomal protein S12. X.laevis 40S ribosomal protein S12 (SW:RS12_XENLA) BLAST Score: 286, sum P(1) = 2.1e-25; Pfam match to entry PF01164 Ribosomal_S12e, Ribosomal protein S12e, 47% identity in 115 aa overlap Pfam match to entry PF01248 Ribosomal_L7Ae, Ribosomal protein L7Ae/L30e/S12e/Gadd45 family, score 111.60, E-value 1.5e-29 23957737 Similarity to 60S ribosomal protein L7. S.cerevisiae 40 ribosomal protein L7-A (SW:RL7A_YEAST) BLAST Score: 547, sum P(1) = 4.7e-53; 44% identity in 239 aa overlap, revised: extended and added 5' exon Pfam match to entry PF00327 Ribosomal_L30, Ribosomal protein L30p/L7e, score 86.50, E-value 9.3e-25 16805166 Similarity to Human EB1 protein. H.sapiens EB1 protein (TR:Q156910) BLAST Score: 325, sum P(2) = 6.2e-35; 46% identity in 122 aa overlap Similar to Xenopus laevis Xeb1A xeb1A SWALL:Q8UW78 (EMBL:AB067727) (295 aa) fasta scores: E(): 1.8e-15, 48.36% id in 122 aa, and to Arabidopsis thaliana microtubule-associated protein eb1-like protein SWALL:Q9FJJ5 (EMBL:AB015469) (293 aa) fasta scores: E(): 1e-14, 47.69% id in 130 aa 16805167 Similarity to ATP-dependent CLP proteases. Synechocystis CLP protease (SW:CLP1_SYNY3) BLAST Score: 442, sum P(1) = 6.3e-42; 48% identity in 179 aa overlap; signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.890, signal anchor probability 0.000) with cleavage site probability 0.268 between residues 15 and 16 Pfam match to entry PF00574 CLP_protease, Clp protease, score 230.90, E-value 1.8e-65 23957738 Revised: added three 3' exons; splicing confirmed in P. knowlesi and P. yoelii 23957739 Revised: added two 5'exons; exons conserved in p. yoelii 23957740 cDNA EST EMBL:T18200 comes from this gene, revised: added two 5' and two 3' exons; splicing conserved in P. yoelii 16805170 Weak match (E-value 0.29) to PF00595 PDZ, PDZ domain (Also known as DHR or GLGF); signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.293, signal anchor probability 0.631) with cleavage site probability 0.142 between residues 23 and 24 16805171 Splicing confirmed in P. yoelii 16805172 Similar to Arabidopsis thaliana DNA polymerase delta small subunit pold2 or at2g42120 or t24p15.3 SWALL:DPD2_ARATH (SWALL:O48520) (456 aa) fasta scores: E(): 4.2e-19, 33.33% id in 378 aa 16805174 Similarity to H.sapiens T-complex protein, eta subunit (SW:TCPH_HUMAN) BLAST Score: 1549, sum P(1) = 3.1e-159; 57% identity in 526 aa overlap; splicing confirmed in P. yeolii and P. knowlesi. Pfam match to entry PF00118 cpn60_TCP1, TCP-1/cpn60 chaperonin family, score 509.20, E-value 3e-149 Similar to Tetrahymena pyriformis t-complex protein 1, eta subunit SWALL:TCPH_TETPY (SWALL:P54409) (558 aa) fasta scores: E(): 1.4e-120, 60.18% id in 530 aa 23957741 Similar to C-terminal half of a number of hypothetical proteins eg AAF29000, human HSPC322 (fragment) (272 aa), fasta scores: opt: 243, E(): 3.6e-11, 30.3% identity in 132 aa overlap, revised: added 3' exon; splicing confirmed in P. yoelii and P. knowlesi 16805177 Possible matrix protein; similar to Mus musculus putative nuclear matrix protein SneV sneV TR:AAK49039 (EMBL:AF251503) (504 aa) fasta scores: E(): 6.6e-23, 33.27% id in 556 aa, contains 7x PFAM matches to PF00400 WD40, WD domain, G-beta repeat 23957742 Revised: added 3' exon; splicing confirmed in P. yoelii and P. knowlesi 23957743 Renamed from PFC0370w; splicing confirmed in P. yoelii and P. knowlesi 16805179 Similar to Arabidopsis thaliana nuclear protein-like SWALL:Q9FMF9 (EMBL:AB008268) (1269 aa) fasta scores: E(): 3.7e-205, 51.64% id in 1305 aa, and to Xenopus laevis splicing factor 3b subunit 1 SWALL:S3B1_XENLA (SWALL:O57683) (1307 aa) fasta scores: E(): 4.9e-205, 52.42% id in 1301 aa, and to Mus musculus splicing factor 3b subunit 1 sf3b1 or sap155 SWALL:S3B1_MOUSE (SWALL:Q99NB9) (1304 aa) fasta scores: E(): 7.2e-205, 52.43% id in 1295 aa 23957744 Similarity to protein phosphatases. S.cerevisiae protein-tyrosine phosphatase YVH1 (SW:PVH1_YEAST) BLAST Score: 123, sum P(3) = 8.6e-13; 37% identity in 69 aa overlap; revised: shortened exon 5 and added exon 6, revised: changed exon 4 donor; splicing confirmed in P. knowlesi Pfam match to entry PF00782 DSPc, Dual specificity phosphatase, catalytic domain, score 52.80, E-value 7.3e-12 23957745 Revised: new gene prediction or could be part of upstream PFC0385c, revised: removed 5' exon, changed donor of second exon; splicing confirmed in P. yoelii and P.knowlesi; signal anchor predicted for PFC0381c by SignalP 2.0 HMM (Signal peptide probabilty 0.297, signal anchor probability 0.676) with cleavage site probability 0.101 between residues 24 and 25 16805182 Similarity to serine/threonine protein kinases. M.musculus serine/threonine protein kinase AIE1 (TR:O88445) BLAST Score: 502, sum P(1) = 4.5e-47; 41% in 260 aa overlap, Match to PF00069 pkinase, Eukaryotic protein kinase domain Score 228.55; splicing confirmed in P. yoelii Pfam match to entry PF00069 pkinase, Protein kinase domain, score 279.80, E-value 3.5e-80 16805183 Similar to Mus musculus 2410127l17riK protein 2410127l17riK SWALL:Q9CWF3 (EMBL:AK010784) (400 aa) fasta scores: E(): 5.4e-31, 42.68% id in 253 aa 16805184 Similarity to many asparagine synthetases. O.sativa asparagine synthetase (SW:ASNS_ORYSA) BLAST Score: 1003, sum P(2) = 5.5e-165; 65% identity in 290 aa overlap; splicing confirmed in P. yoelii Pfam match to entry PF00733 Asn_synthase, Asparagine synthase, score 728.10, E-value 4e-215 Pfam match to entry PF00310 GATase_2, Glutamine amidotransferases class-II, score 120.30, E-value 2.1e-40 16805185 Similarity to 60S acidic ribosomal proteins. B. bovis 60S acidic ribosomal protein P2 (SW:RLA2_BABBO) BLAST Score: 286, sum P(1) = 2.1e-25; 54% identity in 111 aa overlap Pfam match to entry PF00428 60s_ribosomal, 60s Acidic ribosomal protein, score 106.90, E-value 1.2e-32 16805187 Putative homologue of Rat BRAIN protein; some similarity to the C-terminus of R.norvegicus BRAIN protein YT521. R.norvegicus BRAIN protein YT51 (TR:O54729) BLAST Score: 263, sum P(1) = 6.2e-22; 40% in 155 aa overlap; splicing confirmed in P. yoelii; rat BRAIN protein-like 23957746 Revised: extended at 5'end and added two 5' exons 23957747 GC-plots indicate a gene in this region of which this prediction may be an approximation, the predicted splicing is uncertain, revised: new gene prediction; signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.957, signal anchor probability 0.026) with cleavage site probability 0.880 between residues 23 and 24 23957748 Similarity to calcium-dependent protein kinases. P.falciparum calcium-dependent protein kinase CDPK2 (TR:O15865) BLAST Score: 1069, sum P(1) = 2.3e-108; 43% identity in 517 aa overlap; revised: shortened exon 4 and added exon 5, revised: shortened exon 3; splicing confirmed in P. yoelii Pfam match to entry PF00069 pkinase, Protein kinase domain, score 295.00, E-value 9.3e-85 Pfam match to entry PF00036 efhand, EF hand, score 40.00, E-value 5.4e-08 23957749 Revised: removed 5' exon 16805191 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.995, signal anchor probability 0.005) with cleavage site probability 0.397 between residues 17 and 18 16805192 Similarity to helicases. C.elegans helicase (WP:F52B5.3) BLAST Score: 290, sum P(4) = 5.9e-31; 34% in 199 aa overlap Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain, score 48.20, E-value 1.8e-10 23957750 Revised: new gene prediction; splicing confirmed in P. yoelii 23957751 Revised: extended upstream and added exon, GC plots suggest more, similarity: eg to human cDNA AAF29135 HSPC172 (219 aa), fasta scores, opt: 257, E(): 6.9e-11 (40.0% identity in 115 aa overlap); splicing confirmed in P. yoelii and P.knowlesi 16805194 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.022, signal anchor probability 0.976) with cleavage site probability 0.007 between residues 19 and 20; CDS conserved in P. knowlesi 16805196 Revised: shortened at 5' in comparison with P. yoelii 23957752 Revised: changed exon 2 acceptor, added exon 4, splicing confirmed although different pattern of splicing in P. yoelii and P. knowlesi; Match to PF01480 PWI, PWI domain Score 148.85 16805198 Similarity to valyl tRNA synthetases. P.vivax valyl tRNA synthetase (TR:Q26177) BLAST Score: 715, sum P(4) = 3.2e-131; 35% identity in 506 aa overlap; contains IPR002300; tRNA-synt_1a; signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.955, signal anchor probability 0.017) with cleavage site probability 0.339 between residues 18 and 19 Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V), E-value 0.00048; valyl tRNA synthetase, putative 23957753 Revised: new prediction made by joining PFC0475c and PFC0480c with two new exons in between; splicing confirmed in P. yoelii Similar to Arabidopsis thaliana hypothetical 70.3 kDa protein f28b23.7 SWALL:Q9C671 (EMBL:AC079829) (630 aa) fasta scores: E(): 6.2e-13, 29.95% id in 414 aa; hypothetical protein, conserved 23957754 Similarity to serine/threonine protein kinases. P.falciparum protein kinase (TR:Q27731) BLAST Score: 282, sum P(3) = 3.3e-20; 34% identity in 292 aa overlap, revised acceptor for exon 2 Pfam match to entry PF00069 pkinase, Protein kinase domain, score 75.70, E-value 6.5e-20 23957756 Revised: added two 3' exons, some similarity to oligosaccharyl transferase essential subunit; splicing conserved in P.yoelii and P. knowlesi Similar to Homo sapiens dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit precursor rpn1 SWALL:RIB1_HUMAN (SWALL:P04843) (607 aa) fasta scores: E(): 0.0006, 21.17% id in 307 aa 16805204 Contains two matches to PF00026 asp, Eukaryotic aspartyl protease Score 44.11 and 23.85; splicing confirmed in P. yoelii; signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.924, signal anchor probability 0.070) with cleavage site probability 0.667 between residues 24 and 25 Pfam match to entry PF00026 asp, Eukaryotic aspartyl protease, score 192.70, E-value 5.7e-54 Similar to Eimeria tenella aspartyl proteinase eimepsiN SWALL:Q9GN67 (EMBL:AJ293830) (468 aa) fasta scores: E(): 3.9e-72, 46.19% id in 381 aa, and to Rattus norvegicus cathepsin d precursor ctsD SWALL:CATD_RAT (SWALL:P24268) (407 aa) fasta scores: E(): 5.7e-34, 32.61% id in 420 aa 23957757 Revised: extended and added 5' exon; splicing confirmed in P. yoelii and P. knowlesi 23957758 Revised: new gene prediction, REVISED: deleted 3' exon in comparison with P. yoelii and P. knowlesi 16805210 Contains match to PF00097 zf-C3HC4, Zinc finger, C3HC4 type (RING finger) Score 30.90, similarity: part to A. thaliana AAD21704 AT2G20650 (276 aa) fasta scores: opt: 629, E(): 6.9e-29, 38.4% identity in 276 aa overlap 16805211 Pfam match to entry PF00515 TPR, TPR Domain, score 29.80, E-value 6.2e-05 16805212 Similarity to 26S Proteasome regulatory subunit S14. H.sapiens 26S proteasome regulatory subunit S14 (SW:PSD8_HUMAN) BLAST Score: 349, sum P(1) = 4.5e-32; 35% identity in 253 aa overlap 23957759 Similarity to glycogen synthase kinases. D.discoideum glycogen synthase kinase (SW:KG3H_DICDI) BLAST Score: 1001, sum P(1) = 3.7e-101; 51% identity in 393 aa overlap; revised: changed first exon, splicing confirmed in P. yoelii Pfam match to entry PF00069 pkinase, Protein kinase domain, score 291.00, E-value 1.5e-83 16805214 CDS confirmed in P. knowlesi and P. yoelii 16805215 Similarity to 60S ribosomal protein L26. H.sapiens 60S ribosomal protein L26 (SW:RL26_HUMAN) BLAST Score: 400, sum P(1) = 1.8e-37; 63% identity in 123 aa overlap, Match to PF00467 Ribosomal_L24, KOW motif Score 81.49; splicing confirmed in P. knowlesi and P. yoelii Pfam match to entry PF00467 Ribosomal_L24, KOW motif, score 75.10, E-value 1.5e-18 23957760 Revised: added two 5' exons and one 3' exon; hypothetical protein, PFC0540w 23957761 Revised: added 3' exon 16805219 CDS conserved in P. knowlesi and P. yoelii 23957762 Revised: new gene prediction, conserved in P. knowlesi and P. yoelii; could be spliced upstream Similar to Anabaena sp. hypothetical protein Asl2061 asl2061 SWALL:Q8YVB7 (EMBL:AP003588) (92 aa) fasta scores: E(): 4.4e-06, 35% id in 80 aa, and to Guillardia theta hypothetical 10.4 kDa protein Ycf19 ycf19 SWALL:YC19_GUITH (SWALL:O78424) (91 aa) fasta scores: E(): 1.5e-05, 35.13% id in 74 aa 16805221 CDS conserved in P. knowlesi and P. yoelii 23957763 Revised: deleted first exon and added 4 more at 5'; splicing confirmed in P. knowlesi and P. yoelii 23957764 Revised: new gene prediction, revised: removed exon 1, lengthened present exon 4, shortened last exon by comparison with P.yoelii and P.knowelsi 23820924 Possible signal sequence present, revised: added new exon 2, revised: incorporated new intron in last exon in comparison with P. knowlesi and P. yoelii 16805224 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.635, signal anchor probability 0.287) with cleavage site probability 0.594 between residues 21 and 22; CDS conserved in p. knowlesi and P.yoelii 23820925 Revised: new gene prediction, splicing prediction very tentative 23820926 Revised: new gene prediction 23820927 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.921, signal anchor probability 0.075) with cleavage site probability 0.888 between residues 20 and 2, revised: changed donor in comparison with P. knowlesi 16805226 Predicted using hexExon, Pfam: match to entry PF00149 STphosphatase, Ser/Thr protein phosphatase, score 579.40, E-value 2.3e-170 Similar to Dictyostelium discoideum protein phosphatase 6 catalytic subunit pppD SWALL:Q9U9A3 (EMBL:AF176121) (305 aa) fasta scores: E(): 3.1e-83, 60.79% id in 301 aa, and to Malus domestica ser/thr protein phosphatase homologous to PpX ppX SWALL:Q42912 (EMBL:Z47076) (303 aa) fasta scores: E(): 9e-83, 59.8% id in 301 aa; serine/threonine protein phosphatase, putative 23820928 Revised: changed exon 1 and exon 2 acceptor, revised: changed ATG and donor in comparison with P. yoelii 16805228 CDS conserved in P.knowlesi and P. yoelii 16805229 Pfam: match to entry PF00097 zf-C3HC4, Zinc finger, C3HC4 type (RING finger), score 32.80, E-value 8.5e-09; hypothetical protein 23820929 Revised: new genemodel merged PFC0615w (MAL3P5.9) and PFC0620w (MAL3P5.10); PFC0620w (MAL3P5.10) to be obsoleted 16805232 CDS confirmed in P. knowlesi 16805233 Splicing confirmed in P. knowlesi and P. yoelii 16805234 Similarity to initiation factor E4, predicted using hexExon, Pfam: match to entry PF01652 IF4E, Eukaryotic initiation factor 4E, score -34.70, E-value 1.6e-06 16805235 Pfam: 5 matches to entry PF00092 vwa, von Willebrand factor type A domain, 4 matches to entry PF00090 tsp_1, Thrombospondin type 1 domain; Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999, signal anchor probability 0.001) with cleavage site probability 0.759 between residues 23 and 24 Similar to Plasmodium falciparum ctrp SWALL:Q25757 (EMBL:U34363) (2098 aa) fasta scores: E(): 0, 98.48% id in 2114 aa; CTRP protein 23820930 Revised: modified by adding exons 3, 4 and 5 and changing the original 3' exon to three separate exon, splicing conserved in P. yoelii 16805237 Splicing conserved in P. knowlesi and P. yoelii 16805238 CDS conserved in P. knowlesi and P. yoelii; signal anchor predicted for PFC0670c, MAL3P5.18 by SignalP 2.0 HMM (Signal peptide probabilty 0.152, signal anchor probability 0.752) with cleavage site probability 0.054 between residues 23 and 24 23820931 Revised: deleted first exon, CDS confirmed in P. knowlesi and P. yoelii 23820932 Revised: added internal exon 2, splicing confirmed in P. yoelii 23820933 Revised: added 3' exon, splicing confirmed in P. knowlesi and P. yoelii 16805242 CDS conserved in P. knowlesi and P. yoelii; Pfam: match to entry PF00096 zf-C2H2, Zinc finger, C2H2 type, score 21.00, E-value 0.028 23820934 Revised: deleted first exon, chose alternative acceptor sequence, revised: changed donor exon 1; signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.887, signal anchor probability 0.000) with cleavage site probability 0.196 between residues 23 and 24 16805244 CDS conserved in P. knowlesi and P. yeolii 16805245 Revised: new gene prediction; CDS conserved in P. knowlesi and P. yoelii 16805246 Revised: changed splice donor sequence for exon 1; splicing confirmed in P. yoelii 16805247 Similarity to inorganic pyrophosphatases eg C.elegans (TR:Q18680) BLAST Score: 431, sum P(1) = 9.2e-41; 43% identity in 201 aa overlap; splicing confirmed in P. yoelii; Pfam: match to PF00719 Pyrophosphatase, Inorganic pyrophosphatase Score 91.89, E-value 1.8e-40 16805248 CDS confirmed in P. yoelii; signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.815, signal anchor probability 0.000) with cleavage site probability 0.281 between residues 20 and 21 16805249 Revised: extended ORF to upstream initiation codon; CDS conserved in P. knowlesi 16805250 Similarity: eg B.subtilis formate transporter (SW:YWCJ_BACSU) BLAST Score: 271, sum P(1) = 8.3e-24; 31% identity in 236 aa overlap, revised: added two 3' exons, splicing confirmed in P. knowlesi and P. yoelii; Pfam: match to PF01226 Form_Nir_trans, Formate/nitrite transporter Score 125.80, E-value 7.6e-31 16805251 Similarity: eg to DP1_HUMAN polyposis locus protein 1 (TB2 protein). (185 aa) fasta scores: opt: 423, E(): 5.6e-21, 42.0% identity in 150 aa overlap Pfam match to entry PF03134 TB2_DP1_HVA22, , score 189.50, E-value 5.3e-53 16805252 Similarity to 40S ribosomal protein S15A. H.sapiens 40S ribosomal protein S15A (SW:RS1A_HUMAN) BLAST Score: 505, sum P(1) = 1.3e-48; 72% identity in 129 aa overlap, predicted using hexExon, Pfam: matches to PF00410 Ribosomal_S8, Ribosomal protein S8, score 175.90, E-value 6e-53 16805253 Revised: added 5' exon, splicing confirmed in P. yoelii; Pfam: match to PF00097 zf-C3HC4, Zinc finger, C3HC4 type (RING finger) Score 37.17, E-value 1.5e-06 16805254 Similarity to proteasome component C8. A.thaliana proteasome component C8 (SW:PRC8_ARATH) BLAST Score: 448, sum P(1) = 1.5e-42; 34% identity in 252 aa overlap, splicing confirmed in P. knowlesii; Pfam: match to PF00227 proteasome, Proteasome A-type and B-type Score 57.29, E-value 2e-21 16805255 Revised: added internal exon 2, revised: deleted exon 2 in comparison with P. yoelii; signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.981, signal anchor probability 0.000) with cleavage site probability 0.865 between residues 21 and 22 16805256 Highly similar to Plasmodium falciparum 240 kDa antibody recognized protein TR:Q25018 (EMBL:M86715) (787 aa) fasta scores: E(): 7.7e-186, 97.96% id in 785 aa; similarity to cell division control protein kinases. H.sapiens cell division protein kinase 3 (SW:CDK3_HUMAN) BLAST Score: 251, sum P(2) = 3.4e-28; 33% identity in 241 aa overlap; Pfam: 2 matches to PF00069 pkinase, Eukaryotic protein kinase domain Score 110.85 and 46.93, E-value 1.8e-29 and E-value 2.1e-11 respectively Similar to Plasmodium falciparum 240 kDa antibody recognized protein SWALL:Q25018 (EMBL:M86715) (787 aa) fasta scores: E(): 7.7e-186, 97.96% id in 785 aa 16805258 Revised: added 3' exon, splicing confirmed in P. yoelii and P. knowlesi but different in latter 16805259 Splicing confirmed at 5' in P. knowlesi; similarity to kinesins. H.sapiens kinesin-related protein (SW:EG5_HUMAN) BLAST Score: 745, sum P(3) = 2.8e-90; 33% identity in 649 aa overlap, predicted using hexExon Pfam: match to PF00225 kinesin, Kinesin motor domain Score 375.97, E-value 1.1e-115 16805260 Similarity to 40S ribosomal protein S11 eg H.sapiens 40S ribosomal protein S11 (SW:RS11_HUMAN) BLAST Score: 504, sum P(1) = 1.7e-48; 66% identity in 152 aa overlap, revised: changed 5' exon prediction; splicing confirmed but different in P. knowlesi and P. yoelii; Pfam: matches to PF00366 Ribosomal_S17, Ribosomal protein S17 Scores 104.52 and 21.27, E-value 3.2e-39 16805261 Revised: added nine 3' exons, splicing confirmed in P. yoelii 16805262 Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF)., score 4.40, E-value 0.47 Similar to Homo sapiens 26s proteasome non-ATPase regulatory subunit 9 psmd9 SWALL:PSD9_HUMAN (SWALL:O00233) (223 aa) fasta scores: E(): 3.3e-13, 26.12% id in 222 aa, and to Schizosaccharomyces pombe putative 26s proteasome regulatory subunit p27 h omolog spac2h10.02C SWALL:O94393 (EMBL:AL034486) (213 aa) fasta scores: E(): 0.00017, 28.94% id in 228 aa 16805263 Revised: added 5' exon, revise: delete first exon in comparison with P. yoelii 16805264 CDS conserved in P. knowlesi and P. yoelii; signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.919, signal anchor probability 0.002) with cleavage site probability 0.576 between residues 19 and 20 16805265 Similarity to S.pombe hypothetical protein SPBC16G5.07C (TR:O60121) BLAST Score: 700, sum P(1) = 2.9e-69; 46% identity in 297 aa overlap, Pfam: match to PF01145 band_7, SPFH domain / band 7 family Score 200.06, E-value 1.3e-51 Similar to Arabidopsis thaliana similarity to stomatin like protein SWALL:Q9LVW0 (EMBL:AB018115) (401 aa) fasta scores: E(): 3.2e-42, 51.29% id in 308 aa; conserved protein, putative 16805266 Similarity to DNA-directed RNA polymerase II largest subunit. D.melanogaster DNA-directed RNA polymerase II largest subunit (SW:RPB1_DROME) BLAST Score: 1260, sum P(5) = 0.0; 57% identity in 413 aa overlap; Pfam: match to PF00623 RNA_pol_A, RNA polymerase alpha subunit Score 1156.04, match to PF01854 RNA_pol_A2, RNA polymerase A/beta'/A subunit Score 610.60 16805267 Splicing conserved in P. knowlesi 16805268 Revised: split original orf into 2 exons and added 15 3' exons, splicing conserved in P. yoelii 16805269 CDS conserved in P. knowlesi and P. yoelii 16805270 Similar to Drosophila melanogaster Cg1972 protein cg1972 SWALL:Q9VAH9 (EMBL:AE003771) (597 aa) fasta scores: E(): 8.1e-53, 46.97% id in 413 aa, and to Bos taurus cleavage and polyadenylation specificity factor, 73 kDa subunit cpsf3 or cpsf73 SWALL:P79101 (EMBL:X95906) (684 aa) fasta scores: E(): 1.8e-33, 33.33% id in 393 aa 16805271 Almost identical to trophozoite stage antigen SWALL:Q9U627 (EMBL:AF198251); revised: split original PFC0830w into two separate genes Similar to Plasmodium falciparum trophozoite stage antigen k12 SWALL:Q9U627 (EMBL:AF198251) (60 aa) fasta scores: E(): 3.3e-16, 88.33% id in 60 aa; trophozoite stage antigen, PFC0830w 23957765 Similarity to triosephosphate isomerases eg T.cruzi (SW:TPIS_TRYCR) BLAST Score: 183, sum P(2) = 3.6e-18; 32% identity in 134 aa overlap, revised: split original prediction into two genes and added splicing to second (this), similarity starts nearer position 100, Pfam: match to PF00121 TIM, Triosephosphate isomerase Score 69.59, REVISED: removed exon 3, lengthened exon 2; signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.875, signal anchor probability 0.001) with cleavage site probability 0.433 between residues 18 and 1 16805273 Revised: added two 5' exons, the first is tentative, CDS conserved in P. yoelii but cannot confirm splicing at 5'; signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.700, signal anchor probability 0.261) with cleavage site probability 0.649 between residues 22 and 23 16805274 Similarity to P-type ATPase. eg B.taurus chromaffin granule ATPase II (TR:Q29449) BLAST Score: 364, sum P(5) = 1.2e-118; 37% identity in 224 aa overlap, Pfam: contains two matches to PF00122 E1-E2_ATPase Similar to Homo sapiens potential phospholipid-transporting ATPase ia atp8a1 or atpiA SWALL:A8A1_HUMAN (SWALL:Q9Y2Q0) blast scores: E(): 7e-33, score: 361 40% id 16805275 Similarity to hypothetical proteins/ ring finger proteins eg C.elegans protein ZK287.5 (TR:Q23457) BLAST Score: 375, sum P(1) = 7.9e-35; 66% identity in 105 aa overlap, revised: removed first exon and shortened second; CDS conserved in P. knowlesi and P. yoelii 16805276 Revised: extended to upstream initiation codon; CDS conserved in P. yoelii 16805277 Similarity to ubiquitin-conjugating enzyme E2-17 kDa. A.thaliana ubiquitin-conjugating enzyme E2-17 kDa (SW:UBC2_ARATH) BLAST Score: 436, sum P(1) = 2.7e-41; 56% identity in 141 aa overlap, revised: added small 3' exon Pfam match to entry PF00179 UQ_con, Ubiquitin-conjugating enzyme, score 246.30, E-value 4.2e-70 16805278 Similarity: to kinesin-related protein. D.melanogaster kinesin-like protein 67A (TR:P91945) BLAST Score: 664, sum P(2) = 1.9e-67; 28% identity in 707 aa overlap; Pfam: match to PF00225 kinesin (6.1e-86), Kinesin motor domain Score 311.54 E-value 6.1e-86 16805279 Similarity eg to C.elegans RNA-binding protein (TR:Q18318) BLAST Score: 378, sum P(1) = 3.8e-35; 37% identity in 297 aa overlap; splicing conserved in P. knowlesi and P. yoelii; Pfam: match to PF00076 rrm, RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Score 58.01, E-value 1.1e-20 23957766 Similarity to P. falciparum elongation factor 1-beta, (AAF27524) (276 aa), fasta scores: opt: 366, E(): 1.1e-15, 53.2% identity in 141 aa overlap, revised: shortened exon 2, splicing confirmed in P. knowlesi; Pfam: match to PF00736 EF1BD, EF-1 guanine nucleotide exchange domain Score 61.10, E-value 7.9e-22 23957767 Revised: added 3' exon, possibly spliced at 5' end, revised: added 2x 5' exons by similarity with P. knowlesi; signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.001, signal anchor probability 0.997) with cleavage site probability 0.000 between residues 36 and 37 Pfam match to entry PF00005 ABC_tran, ABC transporter, score 72.50, E-value 9e-18 16805282 CDS conserved in P. knowlesi 16805283 CDS conserved in P. knowlesi and P. yoelii 23957768 Revised: new gene prediction, exons 3 and 4 but not 5 confirmed in partial P. knowlesi contig 23957769 Revised: added 2 3' exons, splicing confirmed in P. knowlesi and P. yoelii; similar eg to Mus musculus vesicle trafficking protein sec22b sec22l1 TR:O08547 (EMBL:U91538) (215 aa) fasta scores: E(): 2.1e-09, 31.27% id in 227 aa; contains PFAM synaptobrevin motif 128-214, IPR001388 16805285 CDS conserved in P. knowlesi and P. yoelii but unable to confirm splicing at 5' 16805286 Similarity to T-complex protein 1, epsilon subunit. H.sapiens T-complex protein 1, epsilon subunit (SW:TCPE_HUMAN) BLAST Score: 1585, sum P(1) = 4.8e-163; 55% identity in 532 aa overlap, Pfam: match to PF00118 cpn60_TCP1, TCP-1/cpn60 chaperonin family Score 596.57, E-value 1.5e-167 16805287 CDS conserved in P. knowlesi and P. yoelii; signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.763, signal anchor probability 0.131) with cleavage site probability 0.249 between residues 22 and 23 16805288 CDS conserved in P. knoelesi and P. yoelii Pfam match to entry PF00857 Isochorismatase, Isochorismatase family, score -45.90, E-value 0.071 23957770 Revised: new gene prediction, splicing conserved in P. yoelii 23957771 Revised: new gene prediction, splicing conserved in P. yoelii 16805289 Similarity to eg A.thaliana ATP-dependent RNA helicase (TR:O80838) BLAST Score: 1552, sum P(1) = 1.5e-159; 73% identity in 400 aa overlap, Pfam: match to PF00270 DEAD, DEAD/DEAH box helicase Score 150.75, E-value 4.2e-52; splicing confirmed in P. yoelii; putative ATP-dependent RNA Helicase 16805290 Similarity: eg to C.elegans histone H2A variant (TR:Q27511) BLAST Score: 498, sum P(1) = 7.3e-48; 79% identity in 127 aa overlap, Pfam: match to PF00125 histone, Core histone H2A/H2B/H3/H4 Score 140.44; splicing confirmed in P. knowlesi and P. yoelii Pfam match to entry PF00125 histone, Core histone H2A/H2B/H3/H4, score 153.20, E-value 4.5e-42 23957772 Revised: shortened and added 3' exon, splicing confirmed in P. yoelii; contains possible signal sequence 16805292 CDS conserved in P. yoelii 23957773 Similarity to acetylglucosaminephosphotransferases, eg A. thaliana BAA83586 (431 aa) fasta scores: opt: 998, E(): 0, 43.4% identity in 378 aa overlap, revised: chose alternative exon 1 and shortened exon 2, splicing confirmed in P. yoelii and P.knowlesi; Pfam: match to PF00953 Glycos_transf_4, Glycosyl transferase Score 84.90; E-value 5.2e-47; signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 0.988) with cleavage site probability 0.000 between residues 43 and 44 16805294 Likely to be spliced with at least an upstream exon eg 82389..82653, there is a clear donor but not a clear acceptor for this; CDS conserved in P.knowlesi and P. yoelii 23957774 Pfam: match to PF00069 pkinase, Eukaryotic protein kinase domain Score 37.71,E-value 3.4e-09; revised: added 3 3' exons, revised: deleted exon 4 in comparison with P. knowlesi and P. yoelii; splicing confirmed in P. yoelii Similar to Arabidopsis thaliana putative calcium dependent protein kinase t1g12.7 or f2k15.230 SWALL:Q9SG12 (EMBL:AC012329) (594 aa) fasta scores: E(): 1e-11, 24.69% id in 243 aa 23957775 Revised: extended to upstream initiation codon, CDS confirmed in P. knowlesi and P. yoelii Similar to Rattus norvegicus acylamino-acid-releasing enzyme apeH SWALL:ACPH_RAT (SWALL:P13676) (732 aa) fasta scores: E(): 6.1e-13, 26.61% id in 263 aa, and to Sus scrofa acylamino-acid-releasing enzyme apeH SWALL:ACPH_PIG (SWALL:P19205) (732 aa) fasta scores: E(): 6.5e-12, 27.51% id in 229 aa, and to Homo sapiens oxidized protein hydrolase opH SWALL:Q9P0Y2 (EMBL:AF141383) (732 aa) fasta scores: E(): 5.3e-11, 26.31% id in 228 aa 23957776 Similarity to ATP-dependent RNA helicases eg C. elegans (TR:Q93382) BLAST Score: 282, sum P(2) = 4.9e-36; 26% identity in 293 aa overlap, Pfam: match to PF00270 DEAD, DEAD/DEAH box helicase Score 96.12, match to PF00271 helicase_C, Helicases conserved C-terminal domain Score 68.61, E-value 4.4e-29; revised: added 3' exon, splicing confirmed in P. yoelii and P. knowlesi 23957777 Revised: added two 3' exons, splicing confirmed in P. knowlesi and P. yoelii 16805299 CDS confirmed in P. knowlesi and P. yoelii 23957778 Revised: added six 3' exons, revised: splicing confirmed in P. yoelii although this has a different splicing pattern 16805301 Pfam match to entry PF00160 pro_isomerase, Cyclophilin type peptidyl-prolyl cis-trans isomerase, score 346.50, E-value 3e-100 Similar to Plasmodium falciparum, and Plasmodium falciparum cyclophilin pfc0975C SWALL:Q25756 (EMBL:U33869) (171 aa) fasta scores: E(): 9.6e-72, 100% id in 171 aa 23957779 Revised: added 5' exon, revised; removed 5'exon in comparison with p. knowlesi and P. yoelii Pfam match to entry PF02940 mRNA_triPase, mRNA capping enzyme, beta chain, score 558.50, E-value 4.4e-164 Similar to Plasmodium falciparum hypothetical 72.9 kDa protein pfc0980c, mal3p7.26 SWALL:O97293 (EMBL:AL034559) (617 aa) fasta scores: E(): 1.2e-201, 100% id in 591 aa 23957780 Revised: drastically, merged PFC0985c and PFC990c by making a 14 exon structure, splicing confirmed in P. yoelii but difficult to predict first exon 16805305 Similarity to acyl-coA:cholesterol acyl transferases eg C.elegans (TR:O45245) BLAST Score: 479, sum P(2) = 6.6e-53; 33% identity in 320 aa overlap, Pfam: match to PF01800 ACAT, Sterol O-acyltransferase Score 192.90 Pfam match to entry PF01800 ACAT, Sterol O-acyltransferase, score 165.90, E-value 6.7e-46 Similar to Rattus norvegicus diacylglycerol O-acyltransferase 1 dgat1 or dgaT SWALL:Q9ERM3 (EMBL:AF296131) (498 aa) fasta scores: E(): 1.6e-27, 31.4% id in 328 aa, and to Arabidopsis thaliana diacylglycerol O-acyltransferase at2g19450 or dgat or dagat or f3p11.5 SWALL:AAK96671 (EMBL:AC005917) (520 aa) fasta scores: E(): 9.5e-31, 35.11% id in 336 aa 23957781 Revised: added two 3' exons, splicing confirmed in P. knowlesi and P. yoelii 16805307 Pfam match to entry PF01521 HesB-like, HesB-like domain, score 55.50, E-value 1.1e-12; HesB may be involved in Nitrogen fixation Similar to Chlamydomonas reinhardtii iron-sulfur cluster assembly protein isca SWALL:Q944M8 (EMBL:AF428268) blast scores: E(): 4e-12, score: 74 37% id; HesB-like protein, putative 23957782 CDS conserved in P. knowlesi and P. yoelii but could be unspliced in P. yoelii 23957783 Revised: new gene prediction, probably spliced to PFC1015c by comparison to PFC1015c by comparison to P. knowlesi and P. yoelii 16805309 Probably spliced to PFC1011c by comparison with P.knowlesi and P. yoelii 23957784 Revised: new gene prediction, splicing conserved in P. yoelii and P. knowlesi 16805310 Similarity to 40S ribosomal protein S3A, eg H.annuus (SW:RS3A_HELAN) BLAST Score: 795, sum P(1) = 2.5e-79; 59% identity in 259 aa overlap, Pfam: match to PF01015 Ribosomal_S3Ae, Ribosomal S3Ae family Score 389.66, E-value 2.4e-114 16805311 Splicing confirmed in P. knowlesi and P. yoelii Similar to Drosophila melanogaster Cg16824 protein cg16824 SWALL:Q9VK05 (EMBL:AE003639) (64 aa) fasta scores: E(): 0.0021, 60% id in 40 aa, and to Caenorhabditis elegans F49c12.11 protein f49c12.11 SWALL:Q20588 (EMBL:Z68227) (64 aa) fasta scores: E(): 0.0091, 57.14% id in 42 aa; hypothetical protein, conserved 16805312 CDS conserved in P. knowlesi and P. yoelii 16805313 CDS conserved in P. knowlesi and P. yoelii 16805314 Conserved in P. knowlesi and P. yoelii 16805315 Conserved in P. knowlesi and P. yoelii but spliced in P. knowlesi; signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.999, signal anchor probability 0.000) with cleavage site probability 0.984 between residues 19 and 20 16805316 Splicing confirmed in P. knowlesi and P. yoelii 23957785 Revised: added 3' exon by similarity with P.knowlesi and P. yoelii 16805318 CDS conserved in P. knowlesi and P. yoelii 23957786 Revised: extended and added 5' exon, conserved in P. knowlesi and P. yoelii but splicing may be different 36329000234 pseudo gene, similar to varC 16805320 Some similarity to a larger P. knowlesi CDS 16805321 Similar to P. falciparum chromosome 2, PFB0985C, O96287 predicted integral membrane protein (186 aa), fasta scores: opt: 919, E():0, 78.2% identity in 188 aa overlap, contains potential signal sequence and membrane anchor region 16805322 Similar to Plasmodium falciparum pfc1085c protein pfc1085c or pfb0990C SWALL:O97474 (EMBL:AL034559) (230 aa) fasta scores: E(): 1e-80, 100% id in 230 aa; hypothetical protein, conserved in P. falciparum 16805323 Contains potential signal and membrane anchor regions, similarity: P. falciparum chr. 2, PFB0995W, AAC71987, predicted integral membrane protein (257 aa) fasta scores: opt: 1625, E(): 0, 99.2% identity in 257 aa overlap 16805324 Similarity to other P.falciparum rifins. Member of a multi-gene family, signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.907, signal anchor probability 0.091) with cleavage site probability 0.479 between residues 23 and 24 16805325 Similarity to other P.falciparum rifins. Member of a multi-gene family, predicted using hexExon 16805326 Similarity to other P.falciparum stevors. Member of a multi-gene family, signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.909, signal anchor probability 0.014) with cleavage site probability 0.559 between residues 19 and 20 16805327 Similarity to other P.falciparum rifins. Member of a multi-gene family, signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.631, signal anchor probability 0.016) with cleavage site probability 0.265 between residues 26 and 27 16805328 Similarity to P.falciparum var genes. Part of a multi-gene family Similar to Plasmodium falciparum pfemp1 variant 2 of strain mc mcvar-2 pfemp1 SWALL:Q25734 (EMBL:U27339) (1729 aa) fasta scores: E(): 3.5e-181, 41.08% id in 1806 aa, and to Plasmodium falciparum VaR, mal1p4.01 vaR SWALL:Q9NFB6 (EMBL:AL031747) (2163 aa) fasta scores: E(): 3.4e-132, 46.55% id in 2279 aa; var (3D7-varT3-2) 23509995 Similar to Plasmodium falciparum variant-specific surface protein var-2 SWALL:Q26033 (EMBL:L40609) (2664 aa) fasta scores: E(): 7.8e-149, 43.1% id in 2872 aa 23509996 1 probable transmembrane helix predicted by TMHMM2.0 at aa 328-350 Similar to Plasmodium falciparum rifin pfb0030C SWALL:O96112 (EMBL:AE001367) (370 aa) fasta scores: E(): 3.4e-65, 53.6% id in 375 aa 23509997 Similar to Plasmodium falciparum variant-specific surface protein var-3 SWALL:Q26032 (EMBL:L40609) (3006 aa) fasta scores: E(): 6.2e-103, 43.31% id in 3551 aa 23509998 1 probable transmembrane helix predicted by TMHMM2.0 at aa 340-362 Similar to Plasmodium falciparum RifiN, mal1p4.04 rifiN SWALL:Q9NFB3 (EMBL:AL031747) (372 aa) fasta scores: E(): 1.4e-60, 58.37% id in 382 aa 23509999 1 probable transmembrane helix predicted by TMHMM2.0 at aa 338-360 Similar to Plasmodium falciparum rifin pfb0030C SWALL:O96112 (EMBL:AE001367) (370 aa) fasta scores: E(): 6.9e-67, 54.59% id in 381 aa 23510000 2 probable transmembrane helices predicted by TMHMM2.0 at aa 175-197 and 250-272 Similar to Plasmodium falciparum StevoR isoform troph beta stevoR SWALL:Q9BMD2 (EMBL:AF334955) (282 aa) fasta scores: E(): 3e-74, 83.46% id in 260 aa 23510001 1 probable transmembrane helix predicted by TMHMM2.0 at aa 287-309. Similar to Plasmodium falciparum rifin pfb1035W SWALL:O96292 (EMBL:AE001433) (330 aa) fasta scores: E(): 1.1e-78, 67.87% id in 330 aa 23510002 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.652, signal anchor probability 0.067) with cleavage site probability 0.410 between residues 20 and 21; 1 probable transmembrane helix predicted by TMHMM2.0 at aa 267-289 Similar to Plasmodium falciparum rifin pfb0055C SWALL:O96116 (EMBL:AE001368) (312 aa) fasta scores: E(): 4.3e-53, 57.94% id in 321 aa 23510003 1 probable transmembrane helix predicted by TMHMM2.0 at aa 325-347 Similar to Plasmodium falciparum RifiN, mal1p4.04 rifiN SWALL:Q9NFB3 (EMBL:AL031747) (372 aa) fasta scores: E(): 1.6e-72, 63.92% id in 377 aa 23510004 1 probable transmembrane helix predicted by TMHMM2.0 at aa 333-355 Similar to Plasmodium falciparum rifin pfb1010W SWALL:O96289 (EMBL:AE001432) (368 aa) fasta scores: E(): 9.1e-66, 58.77% id in 376 aa 23510005 1 probable transmembrane helix predicted by TMHMM2.0 at aa 287-309 Similar to Plasmodium falciparum rifin pfb0040C SWALL:O96114 (EMBL:AE001367) (330 aa) fasta scores: E(): 3.5e-49, 49.41% id in 344 aa 36329002663 Stop codon at what would be codon position 141 of exon 2; if it is expressed, it is unlikely to be functional 23510006 3 probable transmembrane helices predicted by TMHMM2.0 at aa 5-24, 254-276 and 305-327; Signal peptide predicted for rifin by SignalP 2.0 HMM (Signal peptide probabilty 0.994, signal anchor probability 0.006) with cleavage site probability 0.290 between residues 27 and 28 Similar to Plasmodium falciparum rifin pfc1095w, mal3p7.50 SWALL:O97309 (EMBL:AL034559) (349 aa) fasta scores: E(): 4e-17, 29.06% id in 351 aa, and to Plasmodium falciparum rifin pfb0040C SWALL:O96114 (EMBL:AE001367) (330 aa) fasta scores: E(): 1.5e-13, 29.56% id in 345 aa 23510007 1 probable transmembrane helix predicted by TMHMM2.0 at aa 332-353; Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.658, signal anchor probability 0.019) with cleavage site probability 0.308 between residues 23 and 24 in P. falciparum Similar to Plasmodium falciparum Pfc0045w, mal3p8.8 protein pfc0045w, mal3p8.8 SWALL:O97329 (EMBL:AL034560) (226 aa) fasta scores: E(): 1.4e-07, 32.72% id in 220 aa 23510008 1 probable transmembrane helix predicted by TMHMM2.0 at aa 7-29; Signal anchor predicted by SignalP2.0 HMM (Signal peptide probabilty 0.188, signal anchor probability 0.720) with cleavage site probability 0.069 between residues 32 and 33. fasta; Similar to Plasmodium falciparum hypothetical 45.0 kDa protein pfb0080C SWALL:O96121 (EMBL:AE001369) blast scores: E(): 6e-10, score: 67 26% id, and to Equine herpesvirus 1 glycoprotein gp2 SWALL:AAK61480 (EMBL:AY034640) (389 aa) fasta scores: E(): 4.3e-15, 40.85% id in 235 aa 23510009 1 probable transmembrane helix predicted by TMHMM2.0 at aa 2-24. putative Similar to Plasmodium falciparum ATP-dept. acyl-coa synthetase pfb0695C SWALL:O96232 (EMBL:AE001412) (888 aa) fasta scores: E(): 1.7e-105, 50.48% id in 933 aa, and to Brassica napus acyl-coa synthetase SWALL:Q96538 (EMBL:X94624) (667 aa) fasta scores: E(): 3.7e-23, 27.99% id in 493 aa 23510010 Partial similarity to Borrelia burgdorferi hypothetical 54.3 KDa protein. Signal anchor predicted by SignalP2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 0.755) with cleavage site probability 0.0000 between residues 46 and 47; 1 probable transmembrane helix predicted by TMHMM2.0 at aa 30-47 Similar to Borrelia burgdorferi virulent strain associated lipoprotein SWALL:Q9ZIU2 (EMBL:AF019082) (460 aa) fasta scores: E(): 8.6e-06, 31.75% id in 148 aa 23510011 N-terminal similarity to RESA protein of P. falciparum. 1 probable transmembrane helix predicted by TMHMM2.0 at aa 20-39;Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.005, signal anchor probability 0.992) with cleavage site probability 0.003 between residues 31 and 32 Similar to Plasmodium falciparum ring-infected erythrocyte surface antigen precursor resA SWALL:RESA_PLAFF (SWALL:P13830) (1073 aa) fasta scores: E(): 1.2e-11, 23.71% id in 409 aa 23510012 Hypothetical protein, later half of the protein moderately similar to Plasmodium vivax Pvstp1 protein; this could be a continuation from the next gene as was originally predicted by the gene finder as part of a large hypothetical protein Similar to Plasmodium falciparum hypothetical 192.3 kDa protein mal1p3.07 SWALL:Q9U0N0 (EMBL:AL031746) (1555 aa) fasta scores: E(): 1.5e-13, 29.31% id in 1211 aa, and to Plasmodium vivax Pvstp1 protein pvstp1 SWALL:Q9N894 (EMBL:AL360354) (826 aa) fasta scores: E(): 3.7e-12, 28.6% id in 395 aa) 23510013 Similarity to P. falciparum hypothetical protein in N-terminus region but not in C-terminus region. 1 probable transmembrane helix predicted by TMHMM2.0 at aa 771-793. Similar to Plasmodium falciparum hypothetical 108.2 kDa protein mal1p3.12 SWALL:Q9U0M5 (EMBL:AL031746) (954 aa) fasta scores: E(): 6.3e-17, 23.8% id in 899 aa 36329002672 Contains suspected frameshift after amino acid sequence YLKELNKKKNVTK binding protein-1 (pfrbp-1) 23510014 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 0.988) with cleavage site probability 0.000 between residues 30 and 31; 1 probable transmembrane helix predicted by TMHMM2.0 at aa 12-29 36329002674 Possible RIF pseudogene, stop codon at what would be codon position 141 in exon II Similar to Plasmodium falciparum rifin pfc1115w, mal3p7.54 SWALL:O97311 (EMBL:AL034559) (371 aa) fasta scores: E(): 2.2e-23, 61.31% id in 137 aa 23510015 1 probable transmembrane helix predicted by TMHMM2.0 at aa 262-284; Signal peptide predicted by SignalP2.0 HMM (Signal peptide probabilty 0.985, signal anchor probability 0.000) with cleavage site probability 0.797 between residues 19 and 20 Similar to Plasmodium falciparum rifin pfb0065W SWALL:O96118 (EMBL:AE001369) (290 aa) fasta scores: E(): 3e-38, 47.86% id in 305 aa 36329002676 Possible RIF pseudogene, match starts at around position 160 after the stop codon in the preceding RIFIN pseudogene. Similar to Plasmodium falciparum RifiN, mal1p4.02 rifiN SWALL:Q9NFB5 (EMBL:AL031747) (331 aa) fasta scores: E(): 1.1e-12, 37.14% id in 175 aa 23510016 Truncated RIFIN; it is possible that it is part of RIFIN pseudogene as there is a stop codon just after the 140 th amino acid position in the exon 2 and even if it is expressed, it is unlikely to be functional Similar to Plasmodium falciparum rifin pfb0060W SWALL:O96117 (EMBL:AE001368) (356 aa) fasta scores: E(): 5.8e-27, 59.23% id in 157 aa 36329002678 VAR, pseudogene 23510018 Not sufficient evidence to annotate it as RCC1 homologue although prosite hit shows weak homology to RCC1 Similar to Arabidopsis thaliana uvb-resistance protein Uvr8 uvr8 SWALL:Q9XHD7 (EMBL:AF130441) blast scores: E(): 1e-04, score: 50 39% id 23510019 Hypothetical protein, similarity primarily to N-terminus of Drosophila melanogaster; sd07741p protein. Similar to Drosophila melanogaster sd07741p cg7971 SWALL:AAK93551 (EMBL:AY052127) (1062 aa) fasta scores: E(): 5.2e-14, 23.92% id in 556 aa, and to Paramecium tetraurelia cyclophilin-RNA interacting protein kin241 SWALL:Q9BHM3 (EMBL:AJ409115) (695 aa) fasta scores: E(): 5.4e-13, 25.52% id in 427 aa 23510020 1 probable transmembrane helix predicted by TMHMM2.0 at aa 7-24 23510021 Alternative splicing could exist. 2 probable transmembrane helices predicted by TMHMM2.0 at aa 297-319 and 339-361 23510022 Similar to Kluyveromyces lactis deubiquitinating enzyme SWALL:Q9HFS7 (EMBL:AF303215) (796 aa) fasta scores: E(): 3e-12, 26.08% id in 391 aa, and to Saccharomyces cerevisiae ubiquitin carboxyl-terminal hydrolase 4 SWALL:UBP4_YEAST (SWALL:P32571) (926 aa) fasta scores: E(): 8.6e-10, 23.36% id in 381 aa, and to Homo sapiens ubiquitin carboxyl-terminal hydrolase 2 usp2 or ubp41 SWALL:UBP2_HUMAN (SWALL:O75604) (353 aa) fasta scores: E(): 1.3e-08, 26.63% id in 368 aa, and to Homo sapiens ubiquitin carboxyl-terminal hydrolase 2 usp2 or ubp41 SWALL:UBP2_HUMAN (SWALL:O75604) (353 aa) fasta scores: E(): 1.3e-08, 26.63% id in 368 aa 23510025 Similar to Homo sapiens CGI-201 protein, short form SWALL:Q9BZJ2 (EMBL:AF318302) (687 aa) fasta scores: E(): 4.4e-79, 40.84% id in 683 aa, and to Arabidopsis thaliana crn SWALL:Q9FNM3 (EMBL:AB006698) (673 aa) fasta scores: E(): 8.3e-78, 42.62% id in 664 aa, and to Drosophila melanogaster crooked neck protein crn or eg:30b8.1 or cg3193 SWALL:O46071 (EMBL:X58374) (702 aa) fasta scores: E(): 6.7e-72, 38% id in 671 aa 23510026 Similar to Arabidopsis thaliana F21f23.4 protein f21f23.4 SWALL:Q9LMY7 (EMBL:AC027656) (341 aa) fasta scores: E(): 1.7e-18, 31.74% id in 315 aa, and to Drosophila melanogaster cg11935 protein cg11935 or cg11938 SWALL:Q9VBX9 (EMBL:AE003750) (286 aa) fasta scores: E(): 6.9e-17, 37.68% id in 207 aa, and to Caenorhabditis elegans K04g2.2 protein k04g2.2 SWALL:Q21221 (EMBL:Z75712) (405 aa) fasta scores: E(): 9e-17, 33.59% id in 256 aa, and to Drosophila melanogaster cg11935 protein cg11935 or cg11938 SWALL:Q9VBX9 (EMBL:AE003750) (286 aa) fasta scores: E(): 6.9e-17, 37.68% id in 207 aa 23510027 Contains SET domain 23510029 Asparagine-rich protein 23510031 Contains internal repeats, alternative gene model possible 23510032 Similar to P. berghei pbs36 protein. 1 probable transmembrane helix predicted by TMHMM2.0 at aa 24-46. Similar to Plasmodium berghei pbs36 SWALL:AAK57743 (EMBL:AY033091) (352 aa) fasta scores: E(): 6.5e-42, 44.86% id in 341 aa, and to Plasmodium yoelii, and Plasmodium yoelii yoelii py52 SWALL:AAK56487 (EMBL:AF390552) (480 aa) fasta scores: E(): 2.2e-09, 26.62% id in 338 aa 23510033 2 probable transmembrane helices predicted by TMHMM2.0 at aa 12-34 and 451-468; Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.053, signal anchor probability 0.880) with cleavage site probability 0.022 between residues 28 and 29. Similar to Plasmodium falciparum pf52 SWALL:Q963C0 (EMBL:AF390553) (478 aa) fasta scores: E(): 3.6e-179, 100% id in 478 aa, and to Plasmodium yoelii, and Plasmodium yoelii yoelii py52 SWALL:Q95NK1 (EMBL:AF390552) (480 aa) fasta scores: E(): 4.1e-63, 42.36% id in 491 aa 23510034 Hypothetical asparagine-rich protein; there is possibility of having 1 or 2 small introns in this large protein. 4 probable transmembrane helices predicted by TMHMM2.0 at aa 1820-1842, 2314-2336, 3399-3416 and 3437-3459 23510035 Contains putative signal peptide; HMMSmart hit Pept_C1 and HMMpfam hit peptidase_C1; BLAST with domain does hit to several proteases Similar to Plasmodium falciparum trophozoite cysteine proteinase precursor SWALL:CYSP_PLAFA (SWALL:P25805) blast scores: E(): 3e-06, score: 56 24% id, and to Entamoeba histolytica cysteine proteinase cp5 SWALL:Q95030 (EMBL:X91644) blast scores: E(): 2e-05, score: 53 26% id 23510036 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.994, signal anchor probability 0.000) with cleavage site probability 0.264 between residues 17 and 18 23510038 Similar to Saccharomyces cerevisiae ATP-dependent RNA helicase dbp6 dbp6 or ynr038w or n3302 SWALL:DBP6_YEAST (SWALL:P53734) (629 aa) fasta scores: E(): 2.2e-09, 26.76% id in 411 aa, and to Plasmodium falciparum ATP-dependent RNA helicase pfc0955w, mal3p7.20 SWALL:O97290 (EMBL:AL034559) (735 aa) fasta scores: E(): 4.1e-08, 24.62% id in 601 aa, and to Schizosaccharomyces pombe putative ATP-dependent RNA helicase c285.03 spcc285.03 SWALL:O74491 (EMBL:AL031545) (604 aa) fasta scores: E(): 1.4e-06, 23.52% id in 459 aa 23510040 Similar to P. yoelii blood stage membrane protein ag-1 homologue Similar to Plasmodium yoelii blood-stage membrane protein ag-1 SWALL:O96672 (EMBL:AF103869) (549 aa) fasta scores: E(): 2.3e-23, 28.42% id in 387 aa 23510041 Signal anchor predicted by SignalP2.0 HMM (Signal peptide probabilty 0.234, signal anchor probability 0.638) with cleavage site probability 0.060 between residues 18 and 19; 2 probable transmembrane helices predicted by TMHMM2.0 at aa 5-27 and 222-244 Similar to Plasmodium falciparum sequestrin SWALL:Q9U0D4 (EMBL:U09839) (652 aa) fasta scores: E(): 1.8e-175, 100% id in 652 aa 23510042 Similarities to several pre-mRNA splicing factor Similar to Arabidopsis thaliana F18b13.15 protein f18b13.15 SWALL:Q9SSD2 (EMBL:AC009322) (2359 aa) fasta scores: E(): 2.2e-215, 60.44% id in 2761 aa, and to Oryza sativa est au065533 SWALL:Q9XE40 (EMBL:AB023482) (2391 aa) fasta scores: E(): 2.2e-215, 60.81% id in 2759 aa, and to Homo sapiens splicing factor prp8 SWALL:O75965 (EMBL:AF092565) (2335 aa) fasta scores: E(): 6.3e-213, 61.29% id in 2759 aa, and to Mus musculus pre-mrna processing 8 protein prpf8 or prp8 SWALL:Q99PV0 (EMBL:AB047391) blast scores: E(): 0.0, score: 3871 68% id 23510044 4 probable transmembrane helices predicted by TMHMM2.0 at aa 89-111, 121-139, 174-193 and 221-243 Similar to Phytophthora infestans secy-independent transporter protein ymf16 SWALL:Q9T238 (EMBL:U17009) (248 aa) fasta scores: E(): 0.25, 24.13% id in 203 aa, and to Plasmodium falciparum predicted integral membrane protein pfb0845W SWALL:O96261 (EMBL:AE001420) (307 aa) fasta scores: E(): 0.39, 23.54% id in 293 aa 23510046 Similar to several bacterial lysine decarboxylases Similar to Mycobacterium tuberculosis hypothetical 106.0 kDa protein adi or rv2531c or mtcy159.25 or mt2607 SWALL:P95022 (EMBL:Z83863) (947 aa) fasta scores: E(): 1.8e-62, 46.44% id in 450 aa, and to Mycobacterium leprae putative amino acid decarboxylase adi or ml0524 SWALL:Q9CCR8 (EMBL:AL583918) (950 aa) fasta scores: E(): 3.1e-60, 45.55% id in 450 aa, and to Eikenella corrodens lysine decarboxylase ecorlD SWALL:Q9Z4R7 (EMBL:U89166) (709 aa) fasta scores: E(): 1.5e-13, 27.98% id in 411 aa 23510048 Weak similarity to Plasmodium falciparum; hypothetical 78.6 kDa protein. 1 probable transmembrane helix predicted by TMHMM2.0 at aa 712-729 Similar to Plasmodium falciparum hypothetical 78.6 kDa protein pfb0680W SWALL:O96229 (EMBL:AE001410) (665 aa) fasta scores: E(): 1.1e-09, 25.61% id in 691 aa 23510049 Weak similarity to Plasmodium falciparum; Pfc0405C protein Similar to Plasmodium falciparum hypothetical 71.5 kDa protein pfc0405c, mal3p3.15 SWALL:O77331 (EMBL:Z98547) (608 aa) fasta scores: E(): 4.2e-07, 26.3% id in 460 aa 23510050 Similar to several vacuolar ATP synthase subunit b. Similar to Plasmodium falciparum vacuolar ATP synthase subunit b vapB SWALL:VATB_PLAFA (SWALL:Q25691) (494 aa) fasta scores: E(): 2.8e-193, 100% id in 494 aa, and to Manduca sexta vacuolar ATP synthase subunit b vha55 SWALL:VATB_MANSE (SWALL:P31401) (494 aa) fasta scores: E(): 4.2e-143, 74.02% id in 485 aa, and to Culex quinquefasciatus b subunit v-ATPase SWALL:O44427 (EMBL:AF037468) (492 aa) fasta scores: E(): 1.3e-142, 73.55% id in 484 aa, and to Aedes aegypti vacuolar ATPase b subunit vatB SWALL:Q9XYC8 (EMBL:AF092934) (496 aa) fasta scores: E(): 5.9e-138, 75.6% id in 455 aa 23510051 Signal peptide predicted for sexual stage-specific protein precursor by SignalP 2.0 HMM (Signal peptide probabilty 0.995, signal anchor probability 0.004) with cleavage site probability 0.896 between residues 25 and 26. precursor Similar to Plasmodium falciparum sexual stage-specific protein precursor SWALL:SSSP_PLAFO (SWALL:P17503) (157 aa) fasta scores: E(): 1.2e-51, 100% id in 157 aa 23510053 Similar to several hydroxyacyl glutathione hydrolases Similar to Arabidopsis thaliana hydroxyacylglutathione hydrolase cytoplasmic glx2-2 or at3g10850 or t7m13.7 SWALL:GL2C_ARATH (SWALL:O24496) (258 aa) fasta scores: E(): 4e-37, 41.76% id in 261 aa, and to Homo sapiens hydroxyacylglutathione hydrolase hagh or hagh1 or glo2 SWALL:GLO2_HUMAN (SWALL:Q16775) (260 aa) fasta scores: E(): 3.3e-34, 39.84% id in 261 aa, and to Mus musculus similar to hydroxyacyl glutathione hydrolase SWALL:Q99KB8 (EMBL:BC004749) (260 aa) fasta scores: E(): 1.4e-33, 39.46% id in 261 aa 23510054 Possible distant homologue of reticulocyte binding proteins of P. falciparum Similar to Plasmodium falciparum hypothetical 136.1 kDa protein mal4p2.01 SWALL:Q9U0M1 (EMBL:AL035475) (1130 aa) fasta scores: E(): 0, 99.46% id in 1130 aa, and to Plasmodium falciparum reticulocyte binding protein 2 homolog a SWALL:Q9BK46 (EMBL:AF312916) (3130 aa) fasta scores: E(): 3.4e-23, 22.92% id in 2753 aa, and to Plasmodium falciparum reticulocyte binding protein 2 homolog b rbP SWALL:AAG02259 (EMBL:AF312917) (3254 aa) fasta scores: E(): 5.8e-21, 21.63% id in 2893 aa 23510055 Possible distant homologue of reticulocyte binding proteins of P. falciparum Similar to Plasmodium falciparum hypothetical 136.1 kDa protein mal4p2.01 SWALL:Q9U0M1 (EMBL:AL035475) (1130 aa) fasta scores: E(): 0, 99.46% id in 1130 aa, and to Plasmodium falciparum reticulocyte binding protein 2 homolog a SWALL:Q9BK46 (EMBL:AF312916) (3130 aa) fasta scores: E(): 3.4e-23, 22.92% id in 2753 aa, and to Plasmodium falciparum reticulocyte binding protein 2 homolog b rbP SWALL:AAG02259 (EMBL:AF312917) (3254 aa) fasta scores: E(): 5.8e-21, 21.63% id in 2893 aa 23510056 Similar to Plasmodium falciparum very hypothetical protein, Mal4p2.02 mal4p2.02 SWALL:Q9U0M0 (EMBL:AL035475) (139 aa) fasta scores: E(): 1.4e-47, 98.57% id in 140 aa 23510057 There is slight modification in the gene model in the last exon from submitted (SWALL:Q9U0L9 (EMBL:AL035475)) Plasmodium falciparum hypothetical 103.2 kDa protein sequence Similar to Plasmodium falciparum hypothetical 103.2 kDa protein mal4p2.03 SWALL:Q9U0L9 (EMBL:AL035475) (853 aa) fasta scores: E(): 0, 100% id in 850 aa 23510058 Similar to Plasmodium falciparum hypothetical 33.9 kDa protein mal4p2.04 SWALL:Q9U0L8 (EMBL:AL035475) (286 aa) fasta scores: E(): 4.9e-117, 98.25% id in 286 aa 23510059 Alternative start site possible; gene model slightly modified from submitted version (SWALL:Q9U0L7 (EMBL:AL035475)) Plasmodium falciparum hypothetical 205.8 kDa protein sequence Similar to Plasmodium falciparum hypothetical 205.8 kDa protein mal4p2.05 SWALL:Q9U0L7 (EMBL:AL035475) (1734 aa) fasta scores: E(): 0, 99.25% id in 1742 aa 23510060 Similar to Plasmodium falciparum hypothetical 48.6 kDa protein mal4p2.06 SWALL:Q9U0L6 (EMBL:AL035475) (405 aa) fasta scores: E(): 1.5e-140, 100% id in 405 aa 23510061 Similar to Schizosaccharomyces pombe hypothetical 28.7 kDa protein c3b9.04 in chromosome ii spbc3b9.04 SWALL:O43033 (EMBL:AL022070) blast scores: E(): 2e-10, score: 68 27% id 23510062 Signal anchor predicted for mal4p2.08 by SignalP 2.0 HMM (Signal peptide probabilty 0.002, signal anchor probability 0.876) with cleavage site probability 0.001 between residues 32 and 33 Similar to Sulfolobus tokodaii hypothetical protein St0208 st0208 SWALL:BAB65167 (EMBL:AP000981) (121 aa) fasta scores: E(): 9.9e-14, 50% id in 126 aa, and to Sulfolobus solfataricus hypothetical protein Sso0175 sso0175 SWALL:Q980V1 (EMBL:AE006655) (120 aa) fasta scores: E(): 1.5e-13, 46.03% id in 126 aa, and to Saccharomyces cerevisiae hypothetical 23.1 kDa protein in shp1-ptc3 intergenic region ybl057c or ybl0510 or ybl0514 SWALL:YBF7_YEAST (SWALL:P34222) (214 aa) fasta scores: E(): 6.6e-10, 37.79% id in 127 aa 23510063 Similar to Plasmodium falciparum putative transcription factor mal4p2.09 SWALL:Q9U0L3 (EMBL:AL035475) (320 aa) fasta scores: E(): 1.9e-101, 100% id in 320 aa 23510065 Similar to Plasmodium falciparum hypothetical 42.7 kDa protein mal4p2.11 SWALL:Q9U0L1 (EMBL:AL035475) (359 aa) fasta scores: E(): 6.2e-116, 94.47% id in 380 aa, and to Saccharomyces cerevisiae putative mitochondrial carrier ygr257c ygr257c or g9175 SWALL:YG5F_YEAST (SWALL:P53320) (366 aa) fasta scores: E(): 1.1e-06, 27.39% id in 303 aa 23510066 Similar to Plasmodium falciparum hypothetical 142.9 kDa protein mal4p2.12 SWALL:Q9U0L0 (EMBL:AL035475) (1212 aa) fasta scores: E(): 0, 100% id in 1212 aa, and to Plasmodium falciparum hypothetical 214.7 kDa protein pfb0540W SWALL:O96201 (EMBL:AE001401) (1844 aa) fasta scores: E(): 7.1e-35, 25.73% id in 1321 aa 23510067 Similar to Plasmodium falciparum hypothetical 197.4 kDa protein mal4p2.13 SWALL:Q9U0K9 (EMBL:AL035475) (1629 aa) fasta scores: E(): 0, 100% id in 1629 aa 23510068 Similar to Plasmodium falciparum hypothetical 230.1 kDa protein mal4p2.14 SWALL:Q9U0K8 (EMBL:AL035475) (1960 aa) fasta scores: E(): 0, 100% id in 1960 aa, and to Plasmodium falciparum hypothetical 179.7 kDa protein mal4p2.44 SWALL:Q9U0H8 (EMBL:AL035475) (1570 aa) fasta scores: E(): 8.3e-22, 23.75% id in 1713 aa 23510069 Originally annotated as a Plasmodium falciparum; hypothetical 77.8 kDa protein SWALL:Q9U0K7 (EMBL:AL035475); present annotation based on high degree of similarity to AAA ATPases domains in HMMpfam and HMMSMART hits and results of fasta / blastp similarity searches Similar to Plasmodium falciparum hypothetical 77.8 kDa protein mal4p2.15 SWALL:Q9U0K7 (EMBL:AL035475) (667 aa) fasta scores: E(): 2.7e-212, 100% id in 667 aa, and to Mus musculus fidgetin-like 1 fignl1 SWALL:Q9ERZ5 (EMBL:AF263914) (683 aa) fasta scores: E(): 4.3e-27, 31.61% id in 427 aa, and to Homo sapiens spastin spast or spg4 or kiaa1083 SWALL:SPAS_HUMAN (SWALL:Q9UBP0) (616 aa) fasta scores: E(): 2.2e-25, 36.78% id in 299 aa 23510070 Similar to Plasmodium falciparum hypothetical 20.9 kDa protein mal4p2.16 SWALL:Q9U0K6 (EMBL:AL035475) (171 aa) fasta scores: E(): 5.6e-65, 100% id in 171 aa 23510071 Similar to Plasmodium falciparum hypothetical 132.5 kDa protein mal4p2.17 SWALL:Q9U0K5 (EMBL:AL035475) (1111 aa) fasta scores: E(): 0, 100% id in 1111 aa 23510072 Similar to Plasmodium falciparum hypothetical 73.3 kDa protein mal4p2.18 SWALL:Q9U0K4 (EMBL:AL035475) (622 aa) fasta scores: E(): 7.6e-159, 100% id in 622 aa 23510073 Similar to Plasmodium falciparum hypothetical 42.2 kDa protein mal4p2.19 SWALL:Q9U0K3 (EMBL:AL035475) (344 aa) fasta scores: E(): 1.4e-119, 100% id in 344 aa 23510074 Similar to Plasmodium falciparum hypothetical 55.2 kDa protein mal4p2.20 SWALL:Q9U0K2 (EMBL:AL035475) (454 aa) fasta scores: E(): 2.7e-164, 100% id in 454 aa 23510075 Similarity to several flap endonucleases Similar to Plasmodium falciparum, and Plasmodium falciparum flap endonuclease 1 fen1 or mal4p2.21 SWALL:Q9U0K1 (EMBL:AF093702) (672 aa) fasta scores: E(): 2.5e-191, 100% id in 672 aa, and to Xenopus laevis flap endonuclease 1 fen1 SWALL:O57351 (EMBL:AF036327) (382 aa) fasta scores: E(): 1.3e-27, 47.79% id in 385 aa, and to Homo sapiens flap endonuclease-1 fen1 SWALL:FEN1_HUMAN (SWALL:P39748) (380 aa) fasta scores: E(): 1.2e-26, 44.83% id in 397 aa 23510076 Signal peptide predicted for mal4p2.22 by SignalP 2.0 HMM (Signal peptide probabilty 0.996, signal anchor probability 0.000) with cleavage site probability 0.764 between residues 21 and 22 Similar to Plasmodium falciparum hypothetical 112.9 kDa protein mal4p2.22 SWALL:Q9U0K0 (EMBL:AL035475) (984 aa) fasta scores: E(): 0, 100% id in 984 aa 23510077 Similar to Chlamydia muridarum mac/perforin family protein tc0431 SWALL:Q9PKN4 (EMBL:AE002310) blast scores: E(): 3e-05, score: 52 23% id, and to Plasmodium falciparum hypothetical 94.5 kDa protein mal4p2.23 SWALL:Q9U0J9 (EMBL:AL035475) (842 aa) fasta scores: E(): 0, 100% id in 842 aa 23510078 Signal peptide predicted for mal4p2.24 by SignalP 2.0 HMM (Signal peptide probabilty 0.786, signal anchor probability 0.000) with cleavage site probability 0.363 between residues 21 and 22 Similar to Plasmodium falciparum hypothetical 37.4 kDa protein mal4p2.24 SWALL:Q9U0J8 (EMBL:AL035475) (315 aa) fasta scores: E(): 2.5e-107, 100% id in 315 aa 23510079 Hypothetical protein with possible glycoprotease-like function; Signal anchor predicted for mal4p2.25 by SignalP 2.0 HMM (Signal peptide probabilty 0.067, signal anchor probability 0.791) with cleavage site probability 0.052 between residues 25 and 26 Similar to Plasmodium falciparum hypothetical 80.8 kDa protein mal4p2.25 SWALL:Q9U0J7 (EMBL:AL035475) (693 aa) fasta scores: E(): 0, 100% id in 693 aa 23510080 Similar to Plasmodium falciparum hypothetical 312.5 kDa protein mal4p2.26 SWALL:Q9U0J6 (EMBL:AL035475) (2567 aa) fasta scores: E(): 0, 100% id in 2567 aa 23510081 Formerly annotated as Plasmodium falciparum conserved hypothetical protein; Mal4p2.27. TR:Q9U0J5 (EMBL:AL035475) Similar to Schizosaccharomyces pombe pre-mrna splicing factor prp31 prp31 or spbc119.13C SWALL:PR31_SCHPO (SWALL:O42904) (518 aa) fasta scores: E(): 6.9e-32, 31.38% id in 497 aa, and to Drosophila melanogaster Cg6876 protein cg6876 SWALL:AAK93352 (EMBL:AE003532) (501 aa) fasta scores: E(): 1.9e-28, 32.99% id in 494 aa 23510082 P. falciparum homologue of yeast SOF1 protein protein Similar to Schizosaccharomyces pombe hypothetical 50.0 kDa trp-asp repeats containing protein c1a4.07c in chromosome ii spbc1a4.07C SWALL:O74340 (EMBL:AL031174) blast scores: E(): 2e-77, score: 736 36% id, and to Plasmodium falciparum putative ribosomal processing protein, Mal4p2.28 mal4p2.28 SWALL:Q9U0J4 (EMBL:AL035475) (482 aa) fasta scores: E(): 2e-182, 100% id in 482 aa, and to Saccharomyces cerevisiae sof1 protein sof1 or yll011w or l1339 SWALL:SOF1_YEAST (SWALL:P33750) (489 aa) fasta scores: E(): 5.5e-37, 34.75% id in 492 aa 23510083 Similar to Plasmodium falciparum hypothetical 120.7 kDa protein mal4p2.29 SWALL:Q9U0J3 (EMBL:AL035475) (1010 aa) fasta scores: E(): 0, 100% id in 1010 aa 23510084 Similar to Plasmodium falciparum DNAJ homologue SWALL:Q9U0J2 (EMBL:AL035475) (672 aa) fasta scores: E(): 0, 100% id in 672 aa, and to Bacillus halodurans chaperone protein DNAJ dnaj or bh1348 SWALL:DNAJ_BACHD (SWALL:Q9KD71) (370 aa) fasta scores: E(): 1.8e-38, 37.36% id in 364 aa, and to Rickettsia prowazekii chaperone protein DNAJ dnaj or rp184 SWALL:DNAJ_RICPR (SWALL:Q9ZDY0) (370 aa) fasta scores: E(): 1.8e-38, 37.07% id in 356 aa, and to Plasmodium falciparum pfj1 SWALL:O15811 (EMBL:D85686) (627 aa) fasta scores: E(): 4.2e-206, 99.83% id in 603 aa 23510085 Signal anchor predicted for mal4p2.31 by SignalP 2.0 HMM (Signal peptide probabilty 0.006, signal anchor probability 0.798) with cleavage site probability 0.002 between residues 23 and 24 Similar to Plasmodium falciparum conserved hypothetical protein, Mal4p2.31 mal4p2.31 SWALL:Q9U0J1 (EMBL:AL035475) (337 aa) fasta scores: E(): 3.5e-121, 100% id in 337 aa, and to Arabidopsis thaliana hypothetical 35.2 kDa protein f24f17.4 SWALL:Q9M7S9 (EMBL:AC068073) (327 aa) fasta scores: E(): 8.2e-11, 26.87% id in 294 aa 23510087 Similar to Plasmodium falciparum putative replication a protein mal4p2.32 SWALL:Q9U0J0 (EMBL:AL035475) (1145 aa) fasta scores: E(): 0, 100% id in 1145 aa, and to Arabidopsis thaliana replication protein a1 SWALL:Q9FME0 (EMBL:AB008269) (629 aa) fasta scores: E(): 2.8e-29, 32.11% id in 467 aa, and to Oryza sativa replication protein a1 os-rpa1 SWALL:O24183 (EMBL:AF009179) (630 aa) fasta scores: E(): 7.8e-27, 29.25% id in 499 aa 23510088 First exon is uncertain; alternative possibility is the first ATG codon in the exon II in this gene model; Signal peptide predicted for mal4p2.33 by SignalP 2.0 HMM (Signal peptide probabilty 0.840, signal anchor probability 0.000) with cleavage site probability 0.292 between residues 21 and 22 Similar to Plasmodium falciparum hypothetical 17.9 kDa protein mal4p2.33 SWALL:Q9U0I9 (EMBL:AL035475) (149 aa) fasta scores: E(): 1.7e-47, 100% id in 149 aa 23510089 Similar to Plasmodium falciparum hypothetical 68.5 kDa protein mal4p2.34 SWALL:Q9U0I8 (EMBL:AL035475) (575 aa) fasta scores: E(): 1.6e-188, 100% id in 575 aa 23510090 Previously annotated as Plasmodium falciparum hypothetical 46.9 kDa protein; TR:Q9U0I7 (EMBL:AL035475); Gene model also changed from the earlier version as new 5' exons incorporated in the new model as compared to the submitted sequence TR:Q9U0I7 (EMBL:AL035475) Similar to Paramecium caudatum actin pc_actinpt1 SWALL:Q966S3 (EMBL:AB070223) blast scores: E(): 3e-15, score: 84 23% id, and to Plasmodium falciparum hypothetical 46.9 kDa protein mal4p2.35 SWALL:Q9U0I7 (EMBL:AL035475) (402 aa) fasta scores: E(): 7.2e-140, 92.54% id in 416 aa, and to Paramecium caudatum actin pc_actinpt1 SWALL:Q966S3 (EMBL:AB070223) (375 aa) fasta scores: E(): 1.2e-13, 23.14% id in 324 aa, and to Caenorhabditis elegans actin-like protein 2 actc or k07c5.1 SWALL:ARP2_CAEEL (SWALL:P53489) (395 aa) fasta scores: E(): 9.5e-12, 24.02% id in 333 aa, and to Schizosaccharomyces pombe actin-like protein arp2 arp2 or spac22f8.01 SWALL:ARP2_SCHPO (SWALL:Q9UUJ1) (390 aa) fasta scores: E(): 2.9e-11, 23.34% id in 317 aa 23510091 Similar to Plasmodium falciparum hypothetical 100.5 kDa protein mal4p2.36 SWALL:Q9U0I6 (EMBL:AL035475) (833 aa) fasta scores: E(): 0, 100% id in 833 aa 23510092 Alternative exon structure possible at the C-terminal end of the protein Similar to Plasmodium falciparum protein phosphatase mal4p2.37 SWALL:Q9U0I5 (EMBL:AL035475) (906 aa) fasta scores: E(): 0, 100% id in 906 aa, and to Arabidopsis thaliana protein phosphatase 2c-like protein f26o13.110 SWALL:Q9SD02 (EMBL:AL133452) (361 aa) fasta scores: E(): 1.2e-20, 32.75% id in 287 aa, and to Mesembryanthemum crystallinum protein phosphatase-2c pp2C SWALL:O82469 (EMBL:AF075580) (359 aa) fasta scores: E(): 2e-19, 37.55% id in 245 aa 23510093 Putative exosome complex exonuclease rrp4; previously annotated as P. falciparum conserved hypothetical protein TR:Q9U0I4 (EMBL:AL035475); Plasmodium falciparum Similar to Schizosaccharomyces pombe probable exosome complex exonuclease rrp4 spac2f7.14C SWALL:RRP4_SCHPO (SWALL:Q09704) blast scores: E(): 2e-36, score: 384 36% id, and to Homo sapiens exosome complex exonuclease Rrp4 rrp4 SWALL:AAH00747 (EMBL:U07561) blast scores: E(): 8e-33, score: 354 33% id, and to Plasmodium falciparum conserved hypothetical protein, Mal4p2.38 mal4p2.38 SWALL:Q9U0I4 (EMBL:AL035475) (338 aa) fasta scores: E(): 4.1e-133, 100% id in 338 aa, and to Schizosaccharomyces pombe probable exosome complex exonuclease rrp4 spac2f7.14C SWALL:RRP4_SCHPO (SWALL:Q09704) (329 aa) fasta scores: E(): 2.3e-26, 34.26% id in 251 aa, and to Trypanosoma brucei Rrp4p homologue rrp4 SWALL:Q95Z16 (EMBL:AJ308995) (301 aa) fasta scores: E(): 5.5e-15, 26.47% id in 272 aa 23510094 Similar to Plasmodium falciparum hypothetical 25.4 kDa protein mal4p2.39 SWALL:Q9U0I3 (EMBL:AL035475) (213 aa) fasta scores: E(): 2.7e-55, 100% id in 213 aa 23510095 Similar to Arabidopsis thaliana hypothetical 36.1 kDa protein t7h20_200 SWALL:Q9LZL7 (EMBL:AL162508) (324 aa) fasta scores: E(): 3.7e-11, 26.97% id in 304 aa, and to Plasmodium falciparum hypothetical 37.1 kDa protein mal4p2.40 SWALL:Q9U0I2 (EMBL:AL035475) (326 aa) fasta scores: E(): 2.4e-112, 100% id in 326 aa 23510096 Signal peptide predicted for mal4p2.41 by SignalP 2.0 HMM (Signal peptide probabilty 0.911, signal anchor probability 0.001) with cleavage site probability 0.388 between residues 17 and 18 Similar to Plasmodium falciparum hypothetical 107.9 kDa protein mal4p2.41 SWALL:Q9U0I1 (EMBL:AL035475) (904 aa) fasta scores: E(): 0, 100% id in 904 aa 23510098 Similar to Plasmodium falciparum hypothetical 117.5 kDa protein mal4p2.43 SWALL:Q9U0H9 (EMBL:AL035475) (977 aa) fasta scores: E(): 0, 100% id in 976 aa 23510099 Similar to Plasmodium falciparum hypothetical 179.7 kDa protein mal4p2.44 SWALL:Q9U0H8 (EMBL:AL035475) (1570 aa) fasta scores: E(): 0, 100% id in 1570 aa 23510100 Similar to Plasmodium falciparum hypothetical 24.0 kDa protein mal4p2.45 SWALL:Q9U0H7 (EMBL:AL035475) (205 aa) fasta scores: E(): 1.7e-71, 100% id in 205 aa 23510101 Signal peptide predicted for mal4p2.46 by SignalP 2.0 HMM (Signal peptide probabilty 0.901, signal anchor probability 0.093) with cleavage site probability 0.405 between residues 19 and 20 Similar to Plasmodium falciparum hypothetical 150.9 kDa protein mal4p2.46 SWALL:Q9U0H6 (EMBL:AL035475) (1245 aa) fasta scores: E(): 0, 100% id in 1245 aa 23510102 Similar to Plasmodium falciparum hypothetical 86.4 kDa protein mal4p2.47 SWALL:Q9U0H5 (EMBL:AL035475) (722 aa) fasta scores: E(): 0, 100% id in 722 aa 23510103 Originally annotated as hypothetical 156.6 kDa protein Similar to Plasmodium falciparum hypothetical 156.6 kDa protein mal4p2.48 SWALL:Q9U0H4 (EMBL:AL035475) (1304 aa) fasta scores: E(): 0, 100% id in 1304 aa, and to Arabidopsis thaliana RNA helicase SWALL:Q9FFQ1 (EMBL:AB005234) (522 aa) fasta scores: E(): 1.3e-08, 23.23% id in 396 aa, and to Schizosaccharomyces pombe putative ATP dependent RNA helicase spbc24c6.02 SWALL:O74764 (EMBL:AL031786) (606 aa) fasta scores: E(): 1.5e-07, 29.46% id in 224 aa 23510104 Similar to Plasmodium falciparum hypothetical 16.6 kDa protein mal4p2.49 SWALL:Q9U0H3 (EMBL:AL035475) (138 aa) fasta scores: E(): 3.2e-44, 100% id in 138 aa 23510105 Similar to Plasmodium falciparum hypothetical 229.7 kDa protein mal4p2.50 SWALL:Q9U0H2 (EMBL:AL035475) (1928 aa) fasta scores: E(): 0, 99.27% id in 1928 aa 23510106 Similar to Plasmodium falciparum DNA polymerase alpha SWALL:Q9U0H1 (EMBL:AL035475) (1912 aa) fasta scores: E(): 0, 100% id in 1911 aa, and to Toxoplasma gondii DNA polymerase alpha catalytic subunit polA SWALL:Q9Y1T1 (EMBL:AF093136) (1690 aa) fasta scores: E(): 3.7e-24, 24.98% id in 1309 aa, and to Saccharomyces cerevisiae DNA polymerase alpha catalytic subunit pol1 or cdc17 or ynl102w or n2181 SWALL:DPOA_YEAST (SWALL:P13382) (1468 aa) fasta scores: E(): 8.8e-19, 23.15% id in 1797 aa 23510107 Slightly different from the submitted sequence (SWALL:Q9U0H0 (EMBL:AL035475)); ~14 amino acids are not present in the present gene model than that of the submitted sequence Similar to Plasmodium falciparum hypothetical 92.2 kDa protein mal4p2.52 SWALL:Q9U0H0 (EMBL:AL035475) (778 aa) fasta scores: E(): 5.7e-184, 98.2% id in 778 aa 23510108 Similar to Plasmodium falciparum possible ribosomal protein mal4p2.53 SWALL:Q9U0G9 (EMBL:AL035475) (336 aa) fasta scores: E(): 1.2e-130, 100% id in 336 aa, and to Euglena gracilis chloroplast 30s ribosomal protein s12 rps12 SWALL:RR12_EUGGR (SWALL:P02368) (124 aa) fasta scores: E(): 1.7e-20, 56.66% id in 120 aa, and to Chlamydomonas reinhardtii chloroplast 30s ribosomal protein s12 rps12 SWALL:RR12_CHLRE (SWALL:P14149) (133 aa) fasta scores: E(): 8.5e-20, 58.71% id in 109 aa, and to Oryza sativa chloroplast 30s ribosomal protein s12 rps12 SWALL:RR12_ORYSA (SWALL:P12149) (124 aa) fasta scores: E(): 1.6e-19, 60.39% id in 101 aa 23510109 Similar to Plasmodium falciparum hypothetical 39.1 kDa protein mal4p2.54 SWALL:Q9U0G8 (EMBL:AL035475) (332 aa) fasta scores: E(): 3.8e-120, 100% id in 332 aa 23510110 Conserved residues at the N-terminal end of the protein Similar to Plasmodium falciparum conserved hypothetical protein, Mal4p2.55 mal4p2.55 SWALL:Q9U0G7 (EMBL:AL035475) (540 aa) fasta scores: E(): 3.6e-193, 100% id in 540 aa, and to Schizosaccharomyces pombe conserved hypothetical protein spcc4b3.18 SWALL:Q9USK7 (EMBL:AL132870) (316 aa) fasta scores: E(): 5.6e-07, 33.33% id in 168 aa 23510111 Similar to Plasmodium falciparum var, mal4p2.56 mal4p2.56, vaR SWALL:Q9U0G6 (EMBL:AL035475) (2209 aa) fasta scores: E(): 0, 100% id in 2209 aa 23510112 Truncated at C-terminal end Similar to Plasmodium falciparum rifin pfb0015C SWALL:O96109 (EMBL:AE001366) (334 aa) fasta scores: E(): 4.5e-23, 39.09% id in 266 aa, and to Plasmodium falciparum rifin pfb1050W SWALL:O96295 (EMBL:AE001434) (327 aa) fasta scores: E(): 1.6e-17, 37.2% id in 250 aa 23510113 Similar to Plasmodium falciparum var, mal4p2.58 mal4p2.58, vaR SWALL:Q9U0G5 (EMBL:AL035475) (2277 aa) fasta scores: E(): 0, 100% id in 2277 aa, and to Plasmodium falciparum variant-specific surface protein var-7 SWALL:Q26034 (EMBL:L42636) (2182 aa) fasta scores: E(): 8.6e-191, 52.01% id in 2353 aa 23510114 Similar to Plasmodium falciparum var, mal4p2.58 mal4p2.58, vaR SWALL:Q9U0G5 (EMBL:AL035475) (2277 aa) fasta scores: E(): 1.5e-143, 52.77% id in 2486 aa, and to Plasmodium falciparum variant-specific surface protein var-7 SWALL:Q26034 (EMBL:L42636) (2182 aa) fasta scores: E(): 1.9e-126, 46.72% id in 2412 aa 23510115 Similar to Plasmodium falciparum var, mal4p2.58 mal4p2.58, vaR SWALL:Q9U0G5 (EMBL:AL035475) (2277 aa) fasta scores: E(): 1.1e-129, 49.19% id in 2498 aa, and to Plasmodium falciparum variant-specific surface protein var-7 SWALL:Q26034 (EMBL:L42636) (2182 aa) fasta scores: E(): 7.9e-126, 46.25% id in 2441 aa 23510116 Similar to Plasmodium falciparum rifin pfc1115w, mal3p7.54 SWALL:O97311 (EMBL:AL034559) (371 aa) fasta scores: E(): 4.8e-58, 49.73% id in 382 aa, and to Plasmodium falciparum rifin pfb0035C SWALL:O96113 (EMBL:AE001367) (375 aa) fasta scores: E(): 1.9e-46, 43.52% id in 386 aa 23510117 Signal peptide predicted for mal1p4.07 by SignalP 2.0 HMM (Signal peptide probabilty 0.895, signal anchor probability 0.008) with cleavage site probability 0.389 between residues 24 and 25 Similar to Plasmodium falciparum RifiN, mal1p4.02 rifiN SWALL:Q9NFB5 (EMBL:AL031747) (331 aa) fasta scores: E(): 9e-53, 50.43% id in 349 aa, and to Plasmodium falciparum rifin, Mal1p4.07 mal1p4.07 SWALL:Q9NFB0 (EMBL:AL031747) (344 aa) fasta scores: E(): 1.3e-50, 48.59% id in 356 aa 23510119 Similar to putative phosphoglycerate mutases of bacterial origin Similar to Streptomyces coelicolor putative phosphoglycerate mutase sco7219 or sc2h12.18C SWALL:Q9K466 (EMBL:AL359215) (208 aa) fasta scores: E(): 0.001, 25.61% id in 203 aa, and to Rhizobium loti phosphoglycerate mutase mlr4643 SWALL:Q98DM0 (EMBL:AP003004) (206 aa) fasta scores: E(): 0.64, 30.53% id in 131 aa, and to Thermoplasma volcanium phosphoglycerate mutase tv0258 or tvg0270675 SWALL:Q97C47 (EMBL:AP000991) (201 aa) fasta scores: E(): 0.83, 32.92% id in 82 aa 23510120 Similarities to several 26s proteasome aaa-ATPase subunit Rpt3 subunit Similar to Arabidopsis thaliana 26s proteasome aaa-ATPase subunit Rpt3 rpt3 SWALL:Q9SEI4 (EMBL:AF123392) (408 aa) fasta scores: E(): 1.9e-98, 72.7% id in 381 aa, and to Drosophila melanogaster rpt3 protein rpt3 or cg16916 SWALL:Q9V405 (EMBL:AE003485) (413 aa) fasta scores: E(): 2.9e-97, 70.75% id in 383 aa, and to Solanum tuberosum 26s protease regulatory subunit 6b homolog SWALL:PRS6_SOLTU (SWALL:P54778) (413 aa) fasta scores: E(): 1.8e-95, 70.6% id in 381 aa 23510121 Similar to Streptomyces coelicolor hypothetical protein sco5140 sco5140 or scp8.03 SWALL:Q9FBL8 (EMBL:AL390975) (252 aa) fasta scores: E(): 2e-18, 50.71% id in 140 aa, and to Caulobacter crescentus hypothetical protein Cc0810 cc0810 SWALL:Q9AA01 (EMBL:AE005757) (260 aa) fasta scores: E(): 5.3e-18, 42.94% id in 163 aa, and to Deinococcus radiodurans hypothetical protein Dr0471 dr0471 SWALL:Q9RX44 (EMBL:AE001906) (256 aa) fasta scores: E(): 1.2e-15, 47.1% id in 138 aa 23510122 Weakly related to several chloroplast ribosomal protein l10; there is possibility of another small exon at the C-terminus Similar to Arabidopsis thaliana ribosomal protein l10-like t6i14_40 SWALL:Q9FY50 (EMBL:AL391710) blast scores: E(): 2e-04, score: 48 29% id, and to Nicotiana tabacum chloroplast ribosomal protein l10 SWALL:O80362 (EMBL:AB010879) (227 aa) fasta scores: E(): 0.016, 24.72% id in 182 aa, and to Oryza sativa 50s ribosomal protein l10 rpl10 SWALL:Q9ZSS9 (EMBL:AF095709) (220 aa) fasta scores: E(): 0.018, 22.84% id in 162 aa, and to Arabidopsis thaliana ribosomal protein l10-like t6i14_40 SWALL:Q9FY50 (EMBL:AL391710) (220 aa) fasta scores: E(): 0.032, 23.92% id in 163 aa 23510123 Similar to several ubiquitin carboxyl-terminal hydrolases hydrolase a Similar to Schizosaccharomyces pombe putative ubiquitin carboxyl-terminal hydrolase c6b1.06c spbc6b1.06C SWALL:Q11119 (EMBL:AL021838) blast scores: E(): 4e-42, score: 437 23% id, and to Mus musculus ubiquitin carboxyl-terminal hydrolase 5 usp5 or isoT SWALL:UBP5_MOUSE (SWALL:P56399) (858 aa) fasta scores: E(): 3.4e-25, 25.42% id in 940 aa, and to Homo sapiens ubiquitin carboxyl-terminal hydrolase 5 usp5 or isoT SWALL:UBP5_HUMAN (SWALL:P45974) (858 aa) fasta scores: E(): 5e-25, 25.42% id in 940 aa, and to Schizosaccharomyces pombe putative ubiquitin carboxyl-terminal hydrolase c6b1.06c spbc6b1.06C SWALL:Q11119 (EMBL:AL021838) (775 aa) fasta scores: E(): 3.7e-17, 26.07% id in 863 aa 23510124 Similarity to several chromosome associated proteins, belonging to SMC superfamily SMC family Similar to Drosophila melanogaster cap protein cap or cg9802 SWALL:Q9VXE9 (EMBL:AE003502) (1211 aa) fasta scores: E(): 2.3e-42, 25.91% id in 1254 aa, and to Arabidopsis thaliana putative chromosome associated protein at2g27170 SWALL:Q9SHT1 (EMBL:AC007290) (1163 aa) fasta scores: E(): 2.8e-30, 25.18% id in 1227 aa, and to Bos taurus Smc3 protein smc3 SWALL:O97594 (EMBL:AF072713) (1218 aa) fasta scores: E(): 5.7e-25, 27.11% id in 1254 aa 23510125 Alternative splicing model is possible at the C-terminus Similar to Schizophyllum commune ribosomal protein s3 rps3 SWALL:Q9G9H3 (EMBL:AF402141) (1453 aa) fasta scores: E(): 8.4e-09, 21.61% id in 1365 aa 23510128 Similar to Homo sapiens RNA-binding protein musashi or 166h1.2 SWALL:O43347 (EMBL:AC003982) (362 aa) fasta scores: E(): 3.4e-17, 38.95% id in 172 aa, and to Mus musculus RNA-binding protein msi1h or mouse-musashi-1 SWALL:Q61474 (EMBL:D49654) (362 aa) fasta scores: E(): 3.9e-17, 38.95% id in 172 aa 23510129 Contains pleckstrin homology (PH) domain homology (PH) domain 23510130 Similar to Pyrococcus abyssi GTP-binding protein, gtp1/obg family obg-like or pab0558 SWALL:Q9V0G4 (EMBL:AJ248285) (357 aa) fasta scores: E(): 3.6e-10, 26.45% id in 310 aa, and to Sulfolobus solfataricus probable GTP-binding protein sso0625 or orf-c08_025 SWALL:Q9UX18 (EMBL:Y18930) (332 aa) fasta scores: E(): 6.4e-09, 29.16% id in 216 aa, and to Homo sapiens putative g-binding protein SWALL:O60747 (EMBL:AF065393) (562 aa) fasta scores: E(): 6.7e-09, 28.69% id in 237 aa 23510132 Contains beta-catenin-like repeats beta-catenin-like repeats 23510133 Similar to several arsenical pump-driving ATPases Similar to Homo sapiens arsenical pump-driving ATPase asna1 SWALL:ARS1_HUMAN (SWALL:O43681) (348 aa) fasta scores: E(): 2.2e-45, 44.14% id in 367 aa, and to Mus musculus arsenical pump-driving ATPase asna1 SWALL:ARS1_MOUSE (SWALL:O54984) (348 aa) fasta scores: E(): 2.2e-45, 44.14% id in 367 aa, and to Schizosaccharomyces pombe putative arsenite-translocating ATPase spac1142.06 SWALL:Q9P7F8 (EMBL:AL159951) (329 aa) fasta scores: E(): 9.1e-43, 46.41% id in 349 aa 23510135 Nearly identical to Plasmodium falciparum malaria antigen fragment (SWALL:Q25905 (EMBL:M63269)) in the N-terminal region Similar to Plasmodium falciparum malaria antigen m26-32-1 SWALL:Q25905 (EMBL:M63269) (138 aa) fasta scores: E(): 2.3e-26, 87.5% id in 136 aa 23510137 Possible cdc2-related protein kinase Similar to Arabidopsis thaliana cdc2-like protein kinase SWALL:Q9LV82 (EMBL:AB019236) blast scores: E(): 1e-43, score: 452 39% id, and to Lycopersicon esculentum cyclin dependent kinase c cdkC SWALL:Q93X47 (EMBL:AJ294903) blast scores: E(): 7e-43, score: 445 38% id, and to Plasmodium yoelii yoelii cdc-2 related kinase 1 crk-1 SWALL:Q9N9G4 (EMBL:AJ271038) blast scores: E(): 5e-40, score: 421 38% id, and to Plasmodium yoelii yoelii cdc-2 related kinase 1 crk-1 SWALL:Q9N9G4 (EMBL:AJ271038) (408 aa) fasta scores: E(): 9.4e-23, 36.74% id in 283 aa, and to Plasmodium falciparum cdc2-related protein kinase 1 crk-1 SWALL:Q25826 (EMBL:X80759) (719 aa) fasta scores: E(): 7.4e-22, 24.4% id in 750 aa 23510138 Similarities to several nonclathrin coat protein zeta2-cop-related proteins zeta2-cop-related protein Similar to Arabidopsis thaliana at1g60970/t7p1_11 SWALL:AAK96635 (EMBL:AY053405) (177 aa) fasta scores: E(): 2.6e-10, 30.19% id in 202 aa, and to Brachydanio rerio nonclathrin coat protein zeta1-cop copz1 SWALL:Q9IB48 (EMBL:AB040044) (177 aa) fasta scores: E(): 5.9e-10, 26.36% id in 201 aa, and to Mus musculus coatomer zeta-2 subunit copz2 SWALL:Q9JHH9 (EMBL:AB047850) (205 aa) fasta scores: E(): 7.6e-10, 27.36% id in 201 aa, and to Homo sapiens coatomer zeta-1 subunit copz or copz1 SWALL:BAB17659 (EMBL:AB047848) (177 aa) fasta scores: E(): 1.2e-09, 26.86% id in 201 aa 23510139 Similarity to several nuclear cap-binding proteins Similar to Arabidopsis thaliana nuclear cap-binding protein cbp20 SWALL:Q9XFD1 (EMBL:AF140219) (257 aa) fasta scores: E(): 3.4e-21, 44.3% id in 158 aa, and to Homo sapiens 20 kDa nuclear cap binding protein ncbp2 or cbp20 SWALL:AAH01255 (EMBL:X84157) (156 aa) fasta scores: E(): 1.3e-18, 46.87% id in 128 aa, and to Drosophila melanogaster cbp20 protein cbp20 or cg12357 SWALL:Q9V3L6 (EMBL:AE003721) (154 aa) fasta scores: E(): 2.3e-18, 48.03% id in 127 aa 23510140 1 /pfam_match=pfam:PF00406;Adenylate kinase;1.9e-28;codon 5-136;prodom:PD000657;PD000657;1e-33;codon 7-183; prosite profile:PS00113;Adenylate kinase signature Confirmed by InterPro eMOTIF pattern match.;8e-5;codon 83-94 psu_db_xref=interpro:IPR000850;Adenylate kinase Similar to Plasmodium falciparum adenylate kinase 1 SWALL:AAK58841 (EMBL:AF308612) (229 aa) fasta scores: E(): 6e-83, 100% id in 229 aa, and to Arabidopsis thaliana putative adenylate kinase at2g37250 SWALL:Q9ZUU1 (EMBL:AC005896) (284 aa) fasta scores: E(): 5.4e-22, 36.32% id in 212 aa, and to Schizosaccharomyces pombe adenylate kinase adk1 or spac4g9.03 SWALL:KAD1_SCHPO (SWALL:P33075) (220 aa) fasta scores: E(): 1.6e-17, 32.53% id in 209 aa 23510141 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.013, signal anchor probability 0.968) with cleavage site probability 0.010 between residues 24 and 25 23510142 Contains RING finger motif domain 23510143 Similarity to several ribosomal protein l15 Similar to Picea mariana 60S ribosomal protein l15-1 sb61 SWALL:R15A_PICMA (SWALL:O65050) (204 aa) fasta scores: E(): 2.5e-47, 64.09% id in 220 aa, and to Homo sapiens ribosomal protein l15 SWALL:Q96S84 (EMBL:AY037163) (204 aa) fasta scores: E(): 1.6e-46, 60.9% id in 220 aa, and to Arabidopsis thaliana ribosomal protein l15 at4g17390 SWALL:O23582 (EMBL:Z97343) (216 aa) fasta scores: E(): 4.1e-46, 62.38% id in 218 aa 23510145 Similar to glutamyl-trnagln amidotransferase subunit a from several bacteria amidotransferase Similar to Clostridium acetobutylicum glutamyl-trnagln amidotransferase subunit a cac2977 SWALL:Q97EX8 (EMBL:AE007794) (478 aa) fasta scores: E(): 2.8e-24, 29.97% id in 417 aa, and to Staphylococcus aureus glutamyl-trna gata or sav1900 or sa1716 SWALL:BAB58062 (EMBL:AP003363) (485 aa) fasta scores: E(): 3.2e-24, 44.07% id in 211 aa, and to Bacillus halodurans glutamyl-trna gata or bh0666 SWALL:GATA_BACHD (SWALL:Q9Z9W9) (485 aa) fasta scores: E(): 1.2e-23, 40.08% id in 237 aa 23510146 Similar to Arabidopsis thaliana expressed protein at2g15270 SWALL:Q9SHU9 (EMBL:AC007267) (213 aa) fasta scores: E(): 0.0016, 28.48% id in 172 aa, and to Drosophila melanogaster Cg8441 protein cg8441 SWALL:Q9V7K1 (EMBL:AE003808) (253 aa) fasta scores: E(): 6.9e-05, 27.02% id in 185 aa 23510147 Similarity to many DNA replication licensing factors factor Similar to Mus musculus DNA replication licensing factor mcm5 mcm5 or mcmd5 or cdc46 SWALL:MCM5_MOUSE (SWALL:P49718) (733 aa) fasta scores: E(): 9.1e-16, 36.29% id in 248 aa, and to Homo sapiens DNA replication licensing factor mcm5 mcm5 or cdc46 SWALL:MCM5_HUMAN (SWALL:P33992) (734 aa) fasta scores: E(): 1.7e-15, 35.48% id in 248 aa, and to Xenopus laevis DNA replication licensing factor mcm5 mcm5 or cdc46 SWALL:MCM5_XENLA (SWALL:P55862) (735 aa) fasta scores: E(): 3.8e-15, 34.67% id in 248 aa 23510148 Not certain about existence of the the last 2 exons 23510149 asparagine-rich protein 23510150 Several weak hits to plant prohibitins Similar to Trypanosoma brucei rhodesiense prohibitin SWALL:O61074 (EMBL:AF049901) blast scores: E(): 0.13, score: 38 24% id, and to Arabidopsis thaliana prohibitin-like protein f21o9.200 or atphb1 or at4g28510 SWALL:O49460 (EMBL:AL021749) (288 aa) fasta scores: E(): 0.41, 28.67% id in 143 aa, and to Arabidopsis thaliana putative prohibitin at2g20530 SWALL:Q9SIL6 (EMBL:AC007109) blast scores: E(): 0.020, score: 41 27% id, and to Brassica napus prohibitin 1-like protein SWALL:Q9AXM0 (EMBL:AF319771) blast scores: E(): 0.026, score: 41 27% id, and to Zea mays prohibitin phb1 SWALL:Q9M589 (EMBL:AF236368) blast scores: E(): 0.078, score: 39 26% id 23510151 Similar to Plasmodium falciparum small GTP-binding protein sar1 SWALL:Q9U8B7 (EMBL:AF104306) (192 aa) fasta scores: E(): 1.9e-71, 100% id in 192 aa, and to Lycopersicon esculentum GTP-binding protein Sar2 sar2 SWALL:SAR2_LYCES (SWALL:P52884) (193 aa) fasta scores: E(): 1e-45, 62.5% id in 192 aa, and to Arabidopsis thaliana GTP-binding protein sar1b sar1b or sar1 or at1g56330 or f14g9.6 SWALL:SARB_ARATH (SWALL:Q01474) (193 aa) fasta scores: E(): 9.8e-45, 62.5% id in 192 aa 23510154 Similarity to several pumilio/mpt5 family RNA-binding proteins of plant origin Similar to Arabidopsis thaliana putative pumilio/mpt5 family RNA-binding protein at2g29200 SWALL:Q9ZW07 (EMBL:AC004561) (968 aa) fasta scores: E(): 1.2e-28, 29.63% id in 324 aa, and to Oryza sativa putative pumilio/mpt5 family RNA-binding protein SWALL:AAK73144 (EMBL:AC079022) (851 aa) fasta scores: E(): 1.9e-28, 30.06% id in 326 aa, and to Arabidopsis thaliana putative pumilio/mpt5 family RNA-binding protein at2g29140 SWALL:Q9ZW02 (EMBL:AC004561) (964 aa) fasta scores: E(): 2.3e-28, 29.32% id in 324 aa, and to Dictyostelium discoideum RNA binding protein PufA pufA SWALL:Q9Y1J5 (EMBL:AF128626) (795 aa) fasta scores: E(): 2.6e-28, 32.51% id in 326 aa 23510155 Similar to Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase SWALL:DRTS_PLAFK (SWALL:P13922) (608 aa) fasta scores: E(): 0, 99.67% id in 608 aa 23510156 Contains 1 putative transmembrane domain; existence of the last 3 small exons is not certain; moderate similarity to leucine zipper-ef-hand containing transmembrane protein 1 from mouse and human Similar to Arabidopsis thaliana F5i14.7 protein f5i14.7 SWALL:O04471 (EMBL:AC001229) (398 aa) fasta scores: E(): 4.8e-19, 28.72% id in 376 aa, and to Mus musculus leucine zipper-ef-hand containing transmembrane protein 1 letm1 SWALL:Q9Z2I0 (EMBL:AF061026) (738 aa) fasta scores: E(): 1.1e-16, 23.96% id in 484 aa, and to Homo sapiens leucine zipper-ef-hand containing transmembrane protein 1 letm1 SWALL:AAH14500 (EMBL:AF061025) (739 aa) fasta scores: E(): 1.2e-16, 24.78% id in 456 aa 23510159 Significant similarity to hypothetical proteins from C. elegans, human; annotated as conserved hypothetical since jalview shows conserved amino acid residues in the middle of the protein Similar to Caenorhabditis elegans hypothetical protein C37c3.8 in chromosome v c37c3.8 SWALL:YC4P_CAEEL (SWALL:Q22915) (302 aa) fasta scores: E(): 2.2e-31, 39.46% id in 261 aa, and to Arabidopsis thaliana At2g25280 protein at2g25280 SWALL:Q9SIR5 (EMBL:AC007070) (291 aa) fasta scores: E(): 3.4e-29, 37.69% id in 252 aa, and to Homo sapiens hypothetical protein CGI-27 SWALL:AAL34462 (EMBL:AF132961) (297 aa) fasta scores: E(): 1.5e-27, 36.68% id in 259 aa 23510161 Similarity to several P. falciparum hypothetical proteins but mostly at the asparagine residues; possibilities exist about 2 smaller proteins: the first 3 exons coding for first protein and another separate protein by the last exon 23510162 There is extra ~20 amino acids at amino acid position 243 of published (TR:Q25826(EMBL:X80759)) Plasmodium falciparum cdc2-related protein kinase 1 sequence Similar to Plasmodium falciparum cdc2-related protein kinase 1 crk-1 SWALL:Q25826 (EMBL:X80759) (719 aa) fasta scores: E(): 3.3e-156, 97.07% id in 719 aa 23510164 Additional 2 small exons possible at C-terminal end 23510166 C-terminal domain similarity to a homology domain of unclear function, occurs in the C-terminal region of several regulatory components of the 26S proteasome as well as in other proteins. This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and TRIP-15). Apparently, all of the characterized proteins containing PCI domains are parts of larger multi-protein complexes. Similar to Schizosaccharomyces pombe cop9/signalosome complex subunit 7b csn7b or spac31a2.01 or spac1751.03 SWALL:CN7B_SCHPO (SWALL:Q09722) blast scores: E(): 6e-12, score: 73 19% id, and to Arabidopsis thaliana hypothetical 46.8 kDa protein f14p3.15 SWALL:AAL32800 (EMBL:AY062722) (417 aa) fasta scores: E(): 1.2e-17, 25.83% id in 360 aa, and to Arabidopsis thaliana hypothetical 49.8 kDa protein t20k14_220 SWALL:Q9LF21 (EMBL:AL391143) (442 aa) fasta scores: E(): 4e-14, 25.34% id in 288 aa 23510167 Weak hits to several hypothetical proteins of P. falciparum 23510169 Similar to several Bet3 proteins Similar to Oryza sativa putative transport protein particle component SWALL:AAK52145 (EMBL:AC084380) (187 aa) fasta scores: E(): 1.2e-35, 55.49% id in 173 aa, and to Arabidopsis thaliana transport protein particle component bet3p-like protein SWALL:Q9FFV2 (EMBL:AB005232) (186 aa) fasta scores: E(): 2.3e-34, 53.33% id in 180 aa, and to Schizosaccharomyces pombe yeast bet3 homolog involved in targeting and fusion of er to golgi transport vesicles, hydrophilic protein that acts in conjunction with snare proteins spac644.18C SWALL:Q9P6P5 (EMBL:AL355012) (183 aa) fasta scores: E(): 6.7e-30, 46.52% id in 187 aa 23510170 Weakly similar to several hypothetical proteins of P. falciparum; very weak hits to regulator of chromosome condensation (RCC1) profile 23510172 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.993, signal anchor probability 0.001) with cleavage site probability 0.856 between residues 19 and 20 Possible 3' exon(s) could exist as evidenced from GC-plot and proteomics data (source: M. Mann) 23510176 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.115, signal anchor probability 0.885) with cleavage site probability 0.060 between residues 23 and 24 Similar to Homo sapiens hypothetical protein CGI-141 SWALL:AAH12455 (EMBL:AF151899) (138 aa) fasta scores: E(): 6.1e-11, 34.81% id in 135 aa, and to Mus musculus hypothetical protein CGI-141 homolog SWALL:Q9CR60 (EMBL:AK018531) (138 aa) fasta scores: E(): 8e-11, 34.07% id in 135 aa, and to Saccharomyces cerevisiae hypothetical 15.4 kDa protein in has1-jnm1 intergenic region ymr292W SWALL:YM8T_YEAST (SWALL:Q03554) (138 aa) fasta scores: E(): 8e-11, 35.65% id in 129 aa 23510178 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.924, signal anchor probability 0.076) with cleavage site probability 0.731 between residues 25 and 26 23510180 Similar to several ran-binding proteins Similar to Brachydanio rerio ran binding protein 1 SWALL:AAK61352 (EMBL:AF364085) (233 aa) fasta scores: E(): 3.3e-12, 40.72% id in 221 aa, and to Homo sapiens ran binding protein SWALL:Q13073 (EMBL:U19240) (215 aa) fasta scores: E(): 3e-11, 43.29% id in 194 aa, and to Xenopus laevis ran binding protein 1 SWALL:P79929 (EMBL:Y09128) (209 aa) fasta scores: E(): 1.5e-10, 40.58% id in 207 aa, and to Lycopersicon esculentum ran binding protein-1 ranbp1 SWALL:AAK53813 (EMBL:AF370443) (224 aa) fasta scores: E(): 3.3e-10, 38.57% id in 210 aa, and to Homo sapiens ran-binding protein 2 ranbp2 or nup358 SWALL:RBP2_HUMAN (SWALL:P49792) (3224 aa) fasta scores: E(): 1.5e-10, 43.29% id in 194 aa 23510181 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.627, signal anchor probability 0.160) with cleavage site probability 0.501 between residues 24 and 25 23510182 Similar to Sulfolobus solfataricus 50s ribosomal protein l7ae rpl7ae or sso0091 or c04_031 SWALL:RL7A_SULSO (SWALL:P55858) blast scores: E(): 9e-08, score: 59 37% id, and to Branchiostoma belcheri nucleolar protein family a member 2 SWALL:AAL02139 (EMBL:AY043319) (126 aa) fasta scores: E(): 3.7e-06, 44.56% id in 92 aa 36329002846 There is a frameshift in the current model; Frameshifted P. falciparum phosphatidylinositol 4-kinase; annotation based on blastp results and pfam match Similar to Schizosaccharomyces pombe putative phosphatidylinositol 4-kinase spbc577.06C SWALL:Q9USR3 (EMBL:AL110506) blast scores: E(): 2e-27, score: 319 38% id, and to Arabidopsis thaliana phosphatidylinositol 4-kinase SWALL:O81129 (EMBL:AF035936) blast scores: E(): 9e-27, score: 313 36% id, and to Solanum tuberosum phosphatidylinositol 4-kinase SWALL:Q9M4P7 (EMBL:AJ005810) blast scores: E(): 4e-26, score: 307 34% id 23510184 Similar to (SWALL:Q9BVS4 (EMBL:BC000953)) Homo sapiens hypothetical 63.3 kDa protein and to Schizosaccharomyces pombe conserved hypothetical protein spbc1703.05 (SWALL:Q9VBU2 (EMBL:AL136536)) Similar to Homo sapiens hypothetical protein SWALL:Q9BVS4 (EMBL:BC000953) (552 aa) fasta scores: E(): 7.7e-47, 37.9% id in 430 aa, and to Mus musculus 2010110k24riK protein 2010110k24riK SWALL:Q9CQS5 (EMBL:AK008451) (547 aa) fasta scores: E(): 1.1e-46, 44.71% id in 331 aa, and to Drosophila melanogaster Cg11859 protein cg11859 SWALL:Q9VBU2 (EMBL:AE003751) (538 aa) fasta scores: E(): 2.5e-46, 36.09% id in 507 aa, and to Schizosaccharomyces pombe conserved hypothetical protein spbc1703.05 SWALL:Q9P7W5 (EMBL:AL136536) (336 aa) fasta scores: E(): 3.8e-42, 43.46% id in 329 aa 23510185 Putative acyl-carrier protein with long N-terminal extension; C-terminal similarity to holo-[acyl-carrier protein] synthase proteins of bacterial origin synthase Similar to Yersinia pestis holo-[acyl-carrier protein] synthase acps or ypo2929 SWALL:CAC92177 (EMBL:AJ414154) blast scores: E(): 4e-08, score: 61 28% id, and to Salmonella typhimurium, and Salmonella typhi holo-[acyl-carrier protein] synthase acps or dpj or stm2577 or sty2823 SWALL:CAD02779 (EMBL:AE008817) blast scores: E(): 8e-08, score: 60 28% id, and to Vibrio cholerae holo-[acyl-carrier protein] synthase acps or vc2457 SWALL:Q9KPB6 (EMBL:AE004316) (126 aa) fasta scores: E(): 0.00052, 34.92% id in 126 aa, and to Escherichia coli holo-[acyl-carrier protein] synthase acps or dpj or b2563 SWALL:ACPS_ECOLI (SWALL:P24224) (125 aa) fasta scores: E(): 0.00088, 29.36% id in 126 aa, and to Clostridium acetobutylicum holo-[acyl-carrier protein] synthase acps or cac0489 SWALL:Q97LR5 (EMBL:AE007563) (124 aa) fasta scores: E(): 0.011, 35.71% id in 126 aa 23510188 Similarity to several prokaryotic ribosome recycling factors; with large N-terminal extension Similar to Borrelia burgdorferi ribosome recycling factor frr or bb0121 SWALL:RRF_BORBU (SWALL:O51147) (184 aa) fasta scores: E(): 0.01, 22.34% id in 179 aa, and to Campylobacter jejuni ribosome recycling factor frr or cj0234C SWALL:Q9PIR0 (EMBL:AL139074) (187 aa) fasta scores: E(): 0.059, 25.14% id in 175 aa 23510189 Similar to Plasmodium falciparum variant-specific surface protein var-7 SWALL:Q26034 (EMBL:L42636) (2182 aa) fasta scores: E(): 1.8e-104, 40.43% id in 2322 aa 23510190 Similar to Plasmodium falciparum pfemp1 pfb1055C SWALL:O96296 (EMBL:AE001434) (2197 aa) fasta scores: E(): 1.2e-107, 44.86% id in 2356 aa 23510191 Similar to Plasmodium falciparum variant-specific surface protein var-2 SWALL:Q26033 (EMBL:L40609) (2664 aa) fasta scores: E(): 4.8e-101, 40.92% id in 2793 aa 23510192 Similar to Plasmodium falciparum rifin pfb1015W SWALL:O96290 (EMBL:AE001432) (348 aa) fasta scores: E(): 5.2e-70, 66.37% id in 348 aa 23510193 Similar to Plasmodium falciparum var pfc1120c, mal3p7.55 SWALL:O97312 (EMBL:AL034559) (2169 aa) fasta scores: E(): 1.3e-143, 47.64% id in 2309 aa 23510194 Similar to Plasmodium falciparum rifin pfb0015C SWALL:O96109 (EMBL:AE001366) (334 aa) fasta scores: E(): 1.1e-39, 49.6% id in 256 aa 36329002859 pseudogene; VAR-related fragment 23510196 Weak similarity to Plasmodium falciparum; hypothetical 202.1 kDa protein (SWALL:O77322 (EMBL:Z98547)) Similar to Plasmodium falciparum hypothetical 202.1 kDa protein pfc0345w, mal3p3.5 SWALL:O77322 (EMBL:Z98547) (1711 aa) fasta scores: E(): 1.7e-15, 23.75% id in 1562 aa 23510199 Similarity to mouse steroid dehydrogenase kik-i and several b-keto acyl reductases from plants Similar to Mus musculus putative steroid dehydrogenase kik-i hsd17b12 or kik1 SWALL:DHBK_MOUSE (SWALL:O70503) (312 aa) fasta scores: E(): 4e-23, 31.66% id in 319 aa, and to Zea mays b-keto acyl reductase glossy8 or gl8 SWALL:O24478 (EMBL:U89509) (326 aa) fasta scores: E(): 7.1e-28, 30.38% id in 316 aa, and to Hordeum vulgare b-keto acyl reductase glossy8 SWALL:O24479 (EMBL:U89510) (325 aa) fasta scores: E(): 7.5e-27, 30.81% id in 318 aa, and to Arabidopsis thaliana b-keto acyl reductase glossy8 SWALL:O24481 (EMBL:U89512) (253 aa) fasta scores: E(): 4.2e-24, 33.6% id in 250 aa 23510200 Asparagine-rich protein 23510201 Similar to Plasmodium falciparum erythrocyte membrane-associated antigen SWALL:Q9GVB6 (EMBL:X53015) fragment sequence; annotation based on published sequence data;PMID: 1896607; membrane-associated antigen Similar to Plasmodium falciparum erythrocyte membrane-associated antigen SWALL:Q9GVB6 (EMBL:X53015) (268 aa) fasta scores: E(): 7.3e-75, 98.87% id in 266 aa 23510202 Similar to Plasmodium falciparum alpha-tubulin ii SWALL:Q25790 (EMBL:M34390) (450 aa) fasta scores: E(): 1.7e-188, 100% id in 450 aa 23510203 Similarity to several 40S ribosomal protein s19 Similar to Ascaris suum 40s ribosomal protein s19s rps19S SWALL:R19S_ASCSU (SWALL:P39698) (150 aa) fasta scores: E(): 1.3e-19, 41.42% id in 140 aa, and to Arabidopsis thaliana putative 40s ribosomal protein s19 f1c9.13 or f1c9_13/at3g02080 SWALL:Q9SGA6 (EMBL:AC011664) (143 aa) fasta scores: E(): 1.5e-19, 44.2% id in 138 aa, and to Emericella nidulans 40s ribosomal protein s19 rps19 or rps16 SWALL:RS19_EMENI (SWALL:P27073) (148 aa) fasta scores: E(): 3.3e-18, 40.9% id in 132 aa, and to Oryza sativa 40s ribosomal protein s19 rps19 SWALL:RS19_ORYSA (SWALL:P40978) (146 aa) fasta scores: E(): 4.4e-18, 38.12% id in 139 aa 23510204 Similar to Homo sapiens u5 small nuclear ribonucleoprotein 200 kDa helicase kiaa0788 SWALL:U520_HUMAN (SWALL:O75643) (1701 aa) fasta scores: E(): 1e-48, 32.61% id in 2177 aa, and to Arabidopsis thaliana F9h16.5 protein f9h16.5 SWALL:Q9SYP1 (EMBL:AC007369) (2171 aa) fasta scores: E(): 3.2e-45, 30.04% id in 2856 aa, and to Schizosaccharomyces pombe putative u5 snrnp-specific 200kd protein spac9.03C SWALL:Q9UT24 (EMBL:AL121764) (2176 aa) fasta scores: E(): 3.7e-41, 29.15% id in 2857 aa 23510206 Similar to several eukaryotic translation initiation factors initiation factor Similar to Oryza sativa putative translation initiation factor SWALL:AAK50586 (EMBL:AC084404) (404 aa) fasta scores: E(): 3.1e-99, 64.84% id in 384 aa, and to Xenopus laevis eukaryotic translation initiation factor xeif-4aiii SWALL:O42226 (EMBL:AF020432) (414 aa) fasta scores: E(): 1.4e-101, 66.14% id in 384 aa, and to Homo sapiens eukaryotic initiation factor 4a-like nuk-34 kiaa0111 SWALL:IF4N_HUMAN (SWALL:P38919) (411 aa) fasta scores: E(): 1.4e-100, 65.62% id in 384 aa, and to Caenorhabditis elegans hypothetical 45.5 kDa protein f33d11.10 SWALL:O44781 (EMBL:AF039720) (399 aa) fasta scores: E(): 6.4e-100, 64.37% id in 393 aa 23510207 The last exon is uncertain; Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.043, signal anchor probability 0.694) with cleavage site probability 0.020 between residues 24 and 25 23510210 Similarity to clathrin assembly proteins or adapter-related proteins Similar to Arabidopsis thaliana putative clathrin assembly protein at2g19790 or f6f22.18/at2g19790 SWALL:AAK44000 (EMBL:AC005169) (143 aa) fasta scores: E(): 2.6e-33, 60.71% id in 140 aa, and to Homo sapiens adapter-related protein complex 4 sigma 1 subunit ap4s1 SWALL:A4S1_HUMAN (SWALL:Q9Y587) (144 aa) fasta scores: E(): 4.7e-32, 55.94% id in 143 aa, and to Schizosaccharomyces pombe putative clathrin-associated protein spap27g11.06C SWALL:Q9P7N2 (EMBL:AL157917) (162 aa) fasta scores: E(): 9.1e-22, 42.95% id in 142 aa 23510212 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.010, signal anchor probability 0.736) with cleavage site probability 0.003 between residues 36 and 37 23510214 Possibilities exit for 2 exons forming 2 separate hypothetical proteins 23510216 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.896, signal anchor probability 0.030) with cleavage site probability 0.297 between residues 22 and 23 conserved in P. falciparum Similar to Plasmodium falciparum predicted integral membrane protein pfb0120W SWALL:O96128 (EMBL:AE001374) (106 aa) fasta scores: E(): 0.00029, 31.53% id in 111 aa, and to Plasmodium chabaudi integral membrane protein SWALL:Q25666 (EMBL:L19784) (173 aa) fasta scores: E(): 0.48, 32.09% id in 81 aa 23510217 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.869, signal anchor probability 0.128) with cleavage site probability 0.514 between residues 25 and 26 23510219 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.050, signal anchor probability 0.950) with cleavage site probability 0.039 between residues 27 and 28 23510220 Similarity to RBP2 (3130 amino acids in length) of P. falciparum (SWALL:Q9BK46 (EMBL:AF312916)) but much smaller (526) in size; Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.097, signal anchor probability 0.743) with cleavage site probability 0.043 between residues 25 and 26 Similar to Plasmodium falciparum reticulocyte binding protein 2 homolog a SWALL:Q9BK46 (EMBL:AF312916) (3130 aa) fasta scores: E(): 1.8e-09, 24.85% id in 511 aa 23510221 Weak similarity to Plasmodium yoelii; rhoptry protein; Also weak similarity to P. vivax RBP Similar to Plasmodium yoelii yoelii 235 kDa rhoptry protein iia.2 SWALL:Q9BJX9 (EMBL:AF323443) (2747 aa) fasta scores: E(): 8.2e-20, 22.28% id in 1804 aa, and to Plasmodium vivax reticulocyte binding protein 1 precursor rbp1 SWALL:RBP1_PLAVB (SWALL:Q00798) (2869 aa) fasta scores: E(): 1.7e-14, 19.53% id in 1577 aa 23510222 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.916, signal anchor probability 0.000) with cleavage site probability 0.576 between residues 21 and 22 EBA-175 homologue Similar to Plasmodium falciparum erythrocyte binding antigen eba-175 SWALL:Q05644 (EMBL:U32207) (1421 aa) fasta scores: E(): 8e-27, 26.7% id in 1498 aa, and to Plasmodium reichenowi erythrocyte binding protein ebP SWALL:Q9N9G9 (EMBL:AJ251848) (1433 aa) fasta scores: E(): 1e-26, 26.61% id in 1458 aa, and to Plasmodium cynomolgi erythrocyte binding protein precursor ebP SWALL:O15852 (EMBL:Y11396) (1045 aa) fasta scores: E(): 3e-22, 26.45% id in 964 aa 23510224 Considerable similarity to Plasmodium falciparum 3.8 protein;Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.006, signal anchor probability 0.984) with cleavage site probability 0.002 between residues 37 and 38 Similar to Plasmodium falciparum Pfc0060c, mal3p8.10 protein pfc0060c, mal3p8.10 SWALL:Q9Y012 (EMBL:AL034560) (587 aa) fasta scores: E(): 6.2e-65, 39.26% id in 545 aa, and to Plasmodium falciparum 3.8 protein 3.8 SWALL:Q25759 (EMBL:Z11832) (332 aa) fasta scores: E(): 1.1e-50, 46.52% id in 331 aa 23510225 Similar to N-terminal region of Plasmodium falciparum ring-infected erythrocyte surface antigen precursor RESA protein, truncated Similar to Plasmodium falciparum ring-infected erythrocyte surface antigen precursor resA SWALL:RESA_PLAFF (SWALL:P13830) (1073 aa) fasta scores: E(): 5.9e-32, 33.65% id in 306 aa 23510226 Similar to Plasmodium falciparum trophozoite antigen r45; with internal repeat structure antigen r45-like protein Similar to Plasmodium falciparum trophozoite antigen r45 SWALL:Q01422 (EMBL:M83793) (668 aa) fasta scores: E(): 5.5e-114, 61.2% id in 1031 aa, and to Staphylococcus epidermidis putative cell-surface adhesin SdrF sdrF SWALL:Q9KI14 (EMBL:AF245041) (1733 aa) fasta scores: E(): 4.3e-53, 33.57% id in 682 aa 23510227 Similar to Plasmodium falciparum trophozoite antigen r45; truncated antigen r45-like protein, truncated Similar to Plasmodium falciparum trophozoite antigen r45 SWALL:Q01423 (EMBL:M83794) (217 aa) fasta scores: E(): 1e-69, 96.72% id in 214 aa 23510231 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.608, signal anchor probability 0.002) with cleavage site probability 0.259 between residues 18 and 19 23510232 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.988, signal anchor probability 0.000) with cleavage site probability 0.910 between residues 19 and 20 conserved in P. falciparum Similar to Plasmodium falciparum predicted integral membrane protein pfb0950W SWALL:O96282 (EMBL:AE001428) (248 aa) fasta scores: E(): 2.6e-25, 45.96% id in 248 aa 23510235 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.941, signal anchor probability 0.000) with cleavage site probability 0.876 between residues 19 and 20 Similar to Plasmodium falciparum StevoR isoform troph alpha stevoR SWALL:Q9BMD3 (EMBL:AF334954) (264 aa) fasta scores: E(): 1.7e-25, 41.69% id in 271 aa 36329002901 RIF pseudogene fragment. The first 25 aa amino acids are missing to obtain usual rifin gene structure. Thus, it is a possibble rifin pseudogene; possibility exits of a truncated rifin protein being coded, 274 aa in length using the first internal methionine codon as the start codon Similar to Plasmodium falciparum rifin pfb0015C SWALL:O96109 (EMBL:AE001366) (334 aa) fasta scores: E(): 9.5e-46, 49.29% id in 282 aa 23510236 Similar to Plasmodium falciparum rifin pfb0040C SWALL:O96114 (EMBL:AE001367) (330 aa) fasta scores: E(): 1.7e-51, 50.59% id in 336 aa 23510237 Similar to Plasmodium falciparum variant-specific surface protein var-3 SWALL:Q26032 (EMBL:L40609) (3006 aa) fasta scores: E(): 8.2e-125, 38.49% id in 3673 aa 23510238 Similar to Plasmodium falciparum rifin pfb1050W SWALL:O96295 (EMBL:AE001434) (327 aa) fasta scores: E(): 1.7e-87, 75.22% id in 327 aa 23510239 Similar to Plasmodium falciparum variant-specific surface protein var-2 SWALL:Q26033 (EMBL:L40609) (2664 aa) fasta scores: E(): 1.7e-136, 37.74% id in 2766 aa 23613363 Subtelomeric var gene Pfam hit to PF03011 Similar to Plasmodium falciparum VaR, mal1p4.01 vaR SWALL:Q9NFB6 (EMBL:AL031747) (2163 aa) fasta scores: E(): 0, 100% id in 2163 aa 23613364 1 probable transmembrane helix predicted for rifin by TMHMM2.0 at aa 289-311. Pfam hit to PF02009, Rifin/stevor family Similar to Plasmodium falciparum RifiN, mal1p4.02 rifiN SWALL:Q9NFB5 (EMBL:AL031747) (331 aa) fasta scores: E(): 1.2e-119, 100% id in 331 aa 23613365 Similar to Plasmodium falciparum var-like protein, Mal1p4.03 mal1p4.03 SWALL:Q9NFB4 (EMBL:AL031747) (1327 aa) fasta scores: E(): 0, 100% id in 1327 aa 23613366 1 probable transmembrane helix predicted for rifin by TMHMM2.0 at aa 330-352 Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 381.40, E-value 1e-111 Similar to Plasmodium falciparum RifiN, mal1p4.04 rifiN SWALL:Q9NFB3 (EMBL:AL031747) (372 aa) fasta scores: E(): 4.7e-129, 100% id in 372 aa, and to Plasmodium falciparum Pfc0035w, mal3p8.6 protein pfc0035w, mal3p8.6 SWALL:O97327 (EMBL:AL034560) (374 aa) fasta scores: E(): 7.3e-63, 55.88% id in 374 aa 36329002910 var fragment, pseudogene Similar to Plasmodium falciparum pfemp1 pfb1045W SWALL:O96294 (EMBL:AE001433) (431 aa) fasta scores: E(): 0.0002, 95.83% id in 24 aa 23613367 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.939, signal anchor probability 0.043) with cleavage site probability 0.561 between residues 24 and 25; 1 probable transmembrane helix predicted by TMHMM2.0 at aa 317-339 Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 314.30, E-value 6e-92 Similar to Plasmodium falciparum rifin, Mal1p4.06 mal1p4.06 SWALL:Q9NFB2 (EMBL:AL031747) (359 aa) fasta scores: E(): 9e-117, 100% id in 359 aa 23613368 Similar to Plasmodium falciparum hypothetical 7.9 kDa protein mal1p4.06 SWALL:Q9NFB1 (EMBL:AL031747) (67 aa) fasta scores: E(): 5.9e-26, 100% id in 67 aa 23613369 1 probable transmembrane helix predicted by TMHMM2.0 at aa 302-324 Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 360.90, E-value 1.2e-105 Similar to Plasmodium falciparum rifin, Mal1p4.07 mal1p4.07 SWALL:Q9NFB0 (EMBL:AL031747) (344 aa) fasta scores: E(): 3.3e-119, 100% id in 344 aa, and to Plasmodium falciparum variant surface antigen rifin 1 rif1 SWALL:Q9U6Q4 (EMBL:AF180393) (337 aa) fasta scores: E(): 9.5e-67, 60.29% id in 345 aa 23613370 1 probable transmembrane helix predicted by TMHMM2.0 at aa 308-330 Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 520.90, E-value 7.7e-153 Similar to Plasmodium falciparum rifin, Mal1p4.08 mal1p4.08 SWALL:Q9NFA9 (EMBL:AL031747) (350 aa) fasta scores: E(): 1.5e-122, 100% id in 350 aa, and to Plasmodium falciparum variant surface antigen rifin 3 rif3 SWALL:Q9U737 (EMBL:AF161311) (350 aa) fasta scores: E(): 7.4e-72, 63.17% id in 353 aa 23613371 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.907, signal anchor probability 0.091) with cleavage site probability 0.479 between residues 23 and 24; 1 probable transmembrane helix predicted by TMHMM2.0 at aa 5-27. Pfam hit to PF02009, Rifinstevor family Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 358.60, E-value 5.3e-105 Similar to Plasmodium falciparum variant surface antigen rifin 3 rif3 SWALL:Q9U737 (EMBL:AF161311) (350 aa) fasta scores: E(): 1.6e-67, 60.16% id in 359 aa 23613372 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.907, signal anchor probability 0.091) with cleavage site probability 0.479 between residues 23 and 24; 1 probable transmembrane helix predicted by TMHMM2.0 at aa 5-27. Pfam hit to PF02009, Rifinstevor family Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 358.60, E-value 5.3e-105 Similar to Plasmodium falciparum variant surface antigen rifin 3 rif3 SWALL:Q9U737 (EMBL:AF161311) (350 aa) fasta scores: E(): 1.6e-67, 60.16% id in 359 aa 23613373 3 probable transmembrane helices predicted by TMHMM2.0 at aa 4-22, 224-246 and 266-288 Similar to Plasmodium falciparum conserved hypothetical membrane protein pfc1090w, mal3p7.49 SWALL:O97308 (EMBL:AL034559) (309 aa) fasta scores: E(): 4.3e-97, 100% id in 309 aa, and to Plasmodium falciparum predicted integral membrane protein pfb0995W SWALL:Q9TY93 (EMBL:AE001431) (257 aa) fasta scores: E(): 5.9e-77, 99.22% id in 257 aa 23613374 Similar to Plasmodium falciparum pfc1085c protein pfc1085c or pfb0990C SWALL:O97474 (EMBL:AL034559) (230 aa) fasta scores: E(): 1e-80, 100% id in 230 aa 23613375 Similar to Plasmodium falciparum predicted integral membrane protein pfb0985C SWALL:O96287 (EMBL:AE001431) (186 aa) fasta scores: E(): 2e-51, 83.42% id in 193 aa 36329002920 Stop codon in the middle of the coding sequence of this P. falciparum conserved protein family Similar to Plasmodium falciparum pfc1075w protein pfc1075w or pfb0980W SWALL:O97462 (EMBL:AL034559) (282 aa) fasta scores: E(): 2.9e-89, 94.68% id in 282 aa 36329002921 VAR-fragement 23613376 Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 568.50, E-value 4.3e-167 Similar to Plasmodium falciparum rifin pfb0030C SWALL:O96112 (EMBL:AE001367) (370 aa) fasta scores: E(): 3.4e-65, 57.44% id in 336 aa, and to Plasmodium falciparum rifin pfb1010W SWALL:O96289 (EMBL:AE001432) (368 aa) fasta scores: E(): 1.3e-61, 55.22% id in 335 aa 36329002923 Similar to Plasmodium falciparum pfemp1 pfb0045C SWALL:O96115 (EMBL:AE001368) (248 aa) fasta scores: E(): 1.6e-76, 88.18% id in 237 aa, and to Plasmodium falciparum pfemp1 pfb0020C SWALL:O96110 (EMBL:AE001366) (440 aa) fasta scores: E(): 8.9e-48, 54.79% id in 438 aa 23613377 Similar to Plasmodium falciparum Stevor, Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.909, signal anchor probability 0.014) with cleavage site probability 0.559 between residues 19 and 20 Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 352.20, E-value 4.1e-103 Similar to Plasmodium falciparum StevoR isoform troph beta stevoR SWALL:Q9BMD2 (EMBL:AF334955) (282 aa) fasta scores: E(): 4.9e-49, 61.71% id in 256 aa, and to Plasmodium falciparum StevoR isoform troph alpha stevoR SWALL:Q9BMD3 (EMBL:AF334954) (264 aa) fasta scores: E(): 1.4e-48, 61.88% id in 265 aa 23613378 Similar to Plasmodium falciparum rifin, Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.970, signal anchormprobability 0.002) with cleavage site probability 0.854 between residues 24 and 25 Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 424.60, E-value 1.9e-124 Similar to Plasmodium falciparum rifin pfb1040W SWALL:O96293 (EMBL:AE001433) (345 aa) fasta scores: E(): 5.6e-65, 60% id in 345 aa, and to Plasmodium falciparum rifin pfb1015W SWALL:O96290 (EMBL:AE001432) (348 aa) fasta scores: E(): 4.3e-62, 56.89% id in 348 aa 23613380 Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, E value 3.30e-17 Similar to Plasmodium falciparum StevoR isoform gam alpha stevoR SWALL:Q9BMD1 (EMBL:AF334956) (197 aa) fasta scores: E(): 9.8e-31, 56.04% id in 182 aa, and to Plasmodium falciparum stevor pfc1105w, mal3p7.52 SWALL:Q9U5M0 (EMBL:AL034559) (301 aa) fasta scores: E(): 1.4e-30, 56.04% id in 182 aa 23613381 Identical to published Plasmodium falciparum resA except amino acid positions between ~850 and ~1000 Pfam match to entry PF00226 DnaJ, DnaJ domain, score -4.70, E-value 0.095 Similar to Plasmodium falciparum ring-infected erythrocyte surface antigen precursor resA SWALL:RESA_PLAFF (SWALL:P13830) (1073 aa) fasta scores: E(): 0, 96.86% id in 1085 aa 23613382 Conserved hypothetical protein, possibly belonging to cf-35 family. Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.943, signal anchor probability 0.000) with cleavage site probability 0.326 between residues 24 and 25 Similar to Clostridium acetobutylicum hypothetical cf-35 family protein Cac1880 cac1880 SWALL:Q97HX6 (EMBL:AE007696) (124 aa) fasta scores: E(): 4, 28.57% id in 91 aa 23613383 Although there are a large number of weak hits to lysophospholipases from plant origin, it did not produce pfam hit to abhydrolase (alphabeta hydrolase) domain (PF00561) and so annotated as hypothetical protein Similar to Arabidopsis thaliana lysophospholipase homolog, putative t9l24.33 SWALL:Q9FX41 (EMBL:AC012396) (407 aa) fasta scores: E(): 9.6e-05, 24.3% id in 251 aa 23613384 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.205, signal anchor probability 0.793) with cleavage site probability 0.141 between residues 26 and 27 Similar to Plasmodium falciparum putative erythrocyte binding protein Ebl-1 ebl-1 SWALL:Q9U4X0 (EMBL:AF131999) (2647 aa) fasta scores: E(): 3e-21, 24.05% id in 1476 aa 23613385 Pfam match to entry PF00069 pkinase, Protein kinase domain, score 24.70, E-value 9.5e-06; HMMSmart match to entry SM0221, STYKc protein kinase domain, E-value 3.7e-03 Similar to Plasmodium falciparum Pfc0060c, mal3p8.10 protein pfc0060c, mal3p8.10 SWALL:Q9Y012 (EMBL:AL034560) (587 aa) fasta scores: E(): 1.6e-64, 40.97% id in 576 aa 23613386 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.802, signal anchor probability 0.162) with cleavage site probability 0.393 between residues 24 and 25 Similar to Plasmodium vivax hypothetical 40.2 kDa protein SWALL:Q9NDV1 (EMBL:Y18842) (326 aa) fasta scores: E(): 2.9e-24, 28.75% id in 240 aa, and to Plasmodium yoelii secreted blood-stage antigen Pag-3 pag-3 SWALL:Q9NGL2 (EMBL:AF250029) (354 aa) fasta scores: E(): 6e-20, 24.9% id in 265 aa 23613387 asparagine-rich hypothetical protein 23613388 Pfam match to entry PF00152 tRNA-synt_2, tRNA synthetases class II (D, K and N), score 330.30, E-value 2.2e-95; HMMTigr hit to TIGR00458, ScanRegExp hit to PS00339, Aminoacyl-transfer RNA synthetases class-II signature 2 Similar to Homo sapiens aspartyl-trna synthetase darS SWALL:Q9BW52 (EMBL:J05032) (501 aa) fasta scores: E(): 1.8e-73, 48.33% id in 451 aa, and to Rattus norvegicus aspartyl-trna synthetase dars or drs1 SWALL:SYD_RAT (SWALL:P15178) (501 aa) fasta scores: E(): 3.1e-73, 48% id in 450 aa 23613393 Similar to Homo sapiens hypothetical protein flj13218 SWALL:Q9H8U6 (EMBL:AK023280) blast scores: E(): 3e-34, score: 373 40% id, and to Macaca fascicularis hypothetical 74.7 kDa protein SWALL:Q9BGS0 (EMBL:AB056403) blast scores: E(): 3e-34, score: 372 40% id, and to Mus musculus nuclear ATP/GTP-binding protein agtpbp1 or 2900054o13rik or nna1 SWALL:Q9EQI4 (EMBL:AF219141) blast scores: E(): 5e-33, score: 362 38% id, and to Drosophila melanogaster Cg11428 protein cg11428 SWALL:Q9VY99 (EMBL:AE003493) blast scores: E(): 4e-27, score: 312 38% id, and to Caenorhabditis elegans hypothetical 55.9 kDa protein Eeed8.6 in chromosome ii eeed8.6 SWALL:YQO6_CAEEL (SWALL:Q09296) blast scores: E(): 5e-26, score: 302 43% id 23613395 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.018, signal anchor probability 0.975) with cleavage site probability 0.005 between residues 25 and 26 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase, score 28.60, E-value 4e-08; Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain, score 11.30, E-value 0.0081; Pfam hit to PF00271, Helicase conserved C-terminal domain 23613396 Lysine-rich protein ProfileScan hit to PS50318, Lysine-rich region 23613397 Very similar to actin 3 from Plasmodium berghei Pfam match to entry PF00022 actin, Actin, score 407.70, E-value 7.3e-124; HMMSmart hit to SM00268, Actin; ScanRegExp hit to PS01132, Actins and actin-related proteins signature confirmed by InterPro eMOTIF pattern match Similar to Plasmodium berghei actin 3 SWALL:Q95Z61 (EMBL:AJ315871) (379 aa) fasta scores: E(): 6.8e-143, 91% id in 378 aa, and to Plasmodium berghei actin 3 SWALL:CAC48194 (EMBL:AJ315871) (386 aa) fasta scores: E(): 3.2e-72, 46.85% id in 397 aa 23613398 Asparagine-rich; Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.251, signal anchor probability 0.742) with cleavage site probability 0.101 between residues 26 and 27 23613399 Pfam match to entry PF00090 tsp_1, Thrombospondin type 1 domain, score 33.40, E-value 5.1e-06; HMMSmart hit to SM00209, Thrombospondin type 1 repeats; ProfileScan hit to PS50092, Thrombospondin type I repeat (TSP1) profile 23613401 The top hit is WEAK hit to a transcription factor from Dictyostelium discoideum (SWALL:P90523 (EMBL:U68754); Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.996, signal anchor probability 0.000) with cleavage site probability 0.882 between residues 23 and 24 Similar to Dictyostelium discoideum putative transcription factor stkA SWALL:P90523 (EMBL:U68754) (872 aa) fasta scores: E(): 0.07, 21.54% id in 297 aa 23613403 Pfam match to entry PF00442 UCH-1, Ubiquitin carboxyl-terminal hydrolases family 2, score 45.50, E-value 1.2e-10; Pfam match to entry PF00443 UCH-2, Ubiquitin carboxyl-terminal hydrolase family 2, score 9.40, E-value 3.4e-12; ScanRegExp hit to PS00972, Ubiquitin carboxyl-terminal hydrolases family 2 signature 1, confirmed by InterPro eMOTIF pattern match Similar to Arabidopsis thaliana ubiquitin-specific protease 25 ubp25 SWALL:Q9FPS2 (EMBL:AF302673) blast scores: E(): 1e-25, score: 298 27% id, and to Mus musculus ubiquitin hydrolyzing enzyme 1 ubh1 SWALL:Q9D9M2 (EMBL:AK006739) blast scores: E(): 1e-16, score: 90 23% id 23613404 Similar to Plasmodium falciparum LytB lytB TR:AAK12102 (EMBL:AF323927). Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.006, signal anchor probability 0.993) with cleavage site probability 0.002 between residues 48 and 49 Pfam match to entry PF02401 LYTB, LytB protein, score 387.30, E-value 1.5e-112; HMMTigr hit to TIGR00216; ScanRegExp hit to PS00092, N-6 Adenine-specific DNA methylases signature Similar to Plasmodium falciparum LytB lytB SWALL:Q9BJX6 (EMBL:AF323927) (535 aa) fasta scores: E(): 3.6e-208, 100% id in 535 aa, and to SWALL:LYTB_CHLPN (SWALL:) (310 aa) fasta scores: E(): 5.3e-46, 48.52% id in 305 aa 23613406 Second exon uncertain 23613408 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.008, signal anchor probability 0.837) with cleavage site probability 0.003 between residues 52 and 53 23613409 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.008, signal anchor probability 0.837) with cleavage site probability 0.003 between residues 52 and 53 23613411 Similar to C-terminus region of adenyl cyclase-related proteins from mouse and human, similarity starts about 320 amino acid downstrem of the start codon in these adenyl cyclase-related proteins; it is not annotated as a putative adenyl cyclase-related protein despite the database hits because this protein is much smaller than other adenyl cyclase-related proteins and the N-terminal conserved residues of other adenyl cyclase-related proteins are absent in this protein HMMSmart match to entry SM0673; CARP; Domain in CAPS (Clyclase associated proteins), E-value 5.7e-07 Similar to Mus musculus adenylyl cyclase-associated protein 1 cap1 or caP SWALL:CAP1_MOUSE (SWALL:P40124) (474 aa) fasta scores: E(): 8.7e-16, 38.31% id in 154 aa, and to Rattus norvegicus adenylyl cyclase-associated protein 1 cap1 or cap or mch1 SWALL:CAP1_RAT (SWALL:Q08163) (474 aa) fasta scores: E(): 2.8e-15, 38.31% id in 154 aa 23613412 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 1.000, signal anchor probability 0.000) with cleavage site probability 0.927 between residues 20 and 21 23613414 ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop) 23613415 Does not match exactly to the previously submitted SWALL:Q03628 (EMBL:M59474) Plasmodium falciparum Pfa35-2 sequence fragment (PMID:1922204) Similar to Plasmodium falciparum asparagine-rich antigen Pfa35-2 pfa35-2 SWALL:Q03628 (EMBL:M59474) (407 aa) fasta scores: E(): 9.3e-110, 97.79% id in 408 aa 23613417 fasta; TR:O96144 (EMBL:AE001381); Plasmodium falciparum; protein with egl-like 3'-5' exonucl. domain; pfb0215C; length 416 aa; id=26.16%; ungapped id=29.61%; E()=3.2e-05; 386 aa overlap; query 58-408 aa; subject 6-381 aa. Putative egl-like 3'-5' exonuclease proteiwith similarity to pfb0215C. Pfam hit to PF01612, 3'-5' exonuclease; HMMSmart hit to SM00474, 3'-5' exonuclease Pfam match to entry PF01612 3_5_exonuclease, 3'-5' exonuclease, score -2.80, E-value 0.00052 Similar to Plasmodium falciparum protein with egl-like 3'-5' exonucl. domain pfb0215C SWALL:O96144 (EMBL:AE001381) (416 aa) fasta scores: E(): 3.2e-05, 26.16% id in 386 aa 23613418 first exon uncertain 23613419 Similar to several vacuolar ATP synthases but it does not produce significant Interpro hits. However, the other vacuolar ATP synthases from other organisms such as human and mouse did not produced any Pfam or Smart hits either; hence, this protein is annotated as putative vacuolar ATP synthase Similar to Mus musculus vacuolar ATP synthase subunit c atp6v1c1 or atp6c or vatC SWALL:VATC_MOUSE (SWALL:Q9Z1G3) (382 aa) fasta scores: E(): 4.3e-28, 31.97% id in 344 aa, and to Drosophila melanogaster vacuolar ATP synthase subunit c vha44 or l(2)06072 or cg8048 SWALL:VATC_DROME (SWALL:Q9V7N5) (388 aa) fasta scores: E(): 5e-28, 32.11% id in 383 aa, and to Homo sapiens vacuolar ATP synthase subunit c atp6v1c1 or atp6c or vatc or atp6D SWALL:VATC_HUMAN (SWALL:P21283) (382 aa) fasta scores: E(): 7.3e-28, 31.12% id in 347 aa 23613421 Plasmodium falciparum calcium-transporting ATPase; Calcium-transporting ATPase. Pfam hit to PF00690, Cation transporter/ATPase, N-terminus; Pfam hit to PF00689, Cation transporting ATPase, C-terminus;Pfam hit to PF00702, haloacid dehalogenase-like hydrolase; ScanRegExp hit to PS00154, E1-E2 ATPases phosphorylation site Pfam match to entry PF00689 Cation_ATPase_C, Cation transporting ATPase, C-terminus, score 281.80, E-value 9e-81; Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase, score 59.80, E-value 5.9e-14; Pfam match to entry PF00690 Cation_ATPase_N, Cation transporter/ATPase, N-terminus, score 73.10, E-value 5.7e-18 Similar to Plasmodium falciparum calcium-transporting ATPase SWALL:ATC_PLAFK (SWALL:Q08853) (1228 aa) fasta scores: E(): 0, 100% id in 1228 aa 23613425 The published (Pubmed ID:97391121) Plasmodium falciparum AARP2 protein sequence (SWALL:Q94649 (EMBL:Y08924)) differs from this model only at the start site and at the internal repeat sites. The sequence was double checked and verified ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop) 23613426 Pfam match to entry PF00071 ras, Ras family, score 238.00, E-value 1.3e-67; smart:SM00175;Rab subfamily of small GTPases;codon 29-206; ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop) Similar to Plasmodium falciparum rab5c gtpase ra5C SWALL:CAD12439 (EMBL:AJ420321) (214 aa) fasta scores: E(): 2.5e-83, 99.53% id in 214 aa, and to Toxoplasma gondii Rab5 rab5 SWALL:Q9GST9 (EMBL:AF296447) (240 aa) fasta scores: E(): 1.7e-46, 65.42% id in 188 aa 23613427 Similar to Plasmodium falciparum hypothetical 94.9 kDa protein pfc0560c, mal3p4.3 SWALL:O77339 (EMBL:AL008970) (784 aa) fasta scores: E(): 1.5e-06, 25.99% id in 477 aa 23613428 Similar to centrins from several organisms Pfam match to entry PF00036 efhand, EF hand, score 25.70, E-value 0.0011; HMMSmart hit to SM00054, EF-hand, calcium binding motif; ProfileScan hit to PS50222, Ca-binding EF-hand motif; ScanRegExp hit to PS00018, EF-hand calcium-binding domain Similar to Marsilea vestita centrin mvcen1 SWALL:O49999 (EMBL:U92973) (170 aa) fasta scores: E(): 2.5e-39, 77.71% id in 166 aa, and to Giardia lamblia centrin SWALL:Q94836 (EMBL:U59300) (162 aa) fasta scores: E(): 5.5e-38, 74.53% id in 161 aa 23613430 It is possible that this acts as transcriptional regulator, Blastp results suggest that there is weak domain homology to CCR4 type transcriptional regulators of N. crassa, Candida albicans and also to a similar transcriptional regulator protein from Schizosaccharomyces pombe Similar to Schizosaccharomyces pombe putative transcriptional regulator spcc31h12.08c or spcc5e4.02C SWALL:O74874 (EMBL:AL031824) blast scores: E(): 1e-15, score: 85 26% id, and to Neurospora crassa related to ccr4 protein 104h10.120 SWALL:Q9C2R2 (EMBL:AL513410) blast scores: E(): 1e-12, score: 75 21% id, and to Candida albicans glucose-repressible alcohol dehydrogenase transcriptional effector ca41c10.13C SWALL:O94047 (EMBL:AL033501) blast scores: E(): 3e-11, score: 71 23% id 23613431 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.915, signal anchor probability 0.022) with cleavage site probability 0.654 between residues 22 and 23 23613432 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.915, signal anchor probability 0.022) with cleavage site probability 0.654 between residues 22 and 23 23613434 Putative patched family protein; Signal anchor predicted by SignalP 2.0 HMM between residues 53 and 54. Pfam hit to PF02460, Patched family Pfam match to entry PF02460 Patched, Patched family, score -28.20, E-value 3e-16 23613435 Putative serine/threonine protein kinase. Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 0.669) with cleavage site probability 0.000 between residues 41 and 42 Pfam match to entry PF00069 pkinase, Protein kinase domain, score 59.00, E-value 2.8e-15; HMMSmart hit to SM00220, Serine/Threonine protein kinases, catalytic domain; ScanRegExp hit to PS00108, Serine/Threonine protein kinases active-site signature Confirmed by InterPro eMOTIF pattern match 23613436 contains potential signal peptide and 4 potential transmembrane domains 23613437 fasta; SW:MR11_HUMAN (P49959); Homo sapiens; double-strand break repair protein mre11a; mre11a or mre11 or hngs1; length 708 aa; id=33.41%; ungapped id=40.64%; E()=1.9e-15; 416 aa overlap; query 346-750 aa; subject 8-360 aa. Putative DNA repair exonuclease, splicing uncertain Alternative splice acceptor site exits for exon2 Pfam match to entry PF02549 DNA_repair, DNA repair exonuclease, score 32.30, E-value 5.6e-18 23613439 Similarity to proteasome subunits Pfam match to entry PF00227 proteasome, Proteasome A-type and B-type, score 72.20, E-value 1.5e-18; ProfileScan hit to PS50247, multispecific proteases of the proteasome Similar to Nicotiana tabacum putative beta 3 proteasome subunit b3 SWALL:CAC43324 (EMBL:AJ291739) (178 aa) fasta scores: E(): 3.6e-17, 43.15% id in 190 aa, and to Giardia lamblia proteasome subunit beta type 3 prsbeta3 SWALL:Q9N9W8 (EMBL:AJ297366) (207 aa) fasta scores: E(): 3.4e-16, 36.69% id in 218 aa, and to Arabidopsis thaliana putative 20s proteasome beta subunit pbc2 t5m16.3 SWALL:Q9CAR1 (EMBL:AC010704) (191 aa) fasta scores: E(): 1.9e-14, 45.09% id in 204 aa 23613441 asparagine-rich Similar to Plasmodium falciparum asparagine-rich protein SWALL:O96422 (EMBL:AF047005) (728 aa) fasta scores: E(): 4.3e-193, 99.58% id in 728 aa 23613442 splicing uncertain; weak similarities to mitochondrial fad carrier proteins; a distant homolgue of mitochondrial fad carrier protein Pfam match to entry PF00153 mito_carr, Mitochondrial carrier protein, score 42.80, E-value 7.9e-09; ScanRegExp hit to PS00215, mitochondrial energy transfer proteins signature Confirmed by InterPro eMOTIF pattern match Similar to Saccharomyces cerevisiae mitochondrial fad carrier protein flx1 flx1 or yil134W SWALL:FLX1_YEAST (SWALL:P40464) (311 aa) fasta scores: E(): 0.7, 36.2% id in 58 aa 23613443 Very weak hit (7.20e-01) to ELM2 domain Pfam match to entry PF01448 ELM2, ELM2 domain, score 8.10, E-value 0.72;ProfileScan hit to PS50313, Glutamic acid-rich region 23613445 contains possible signal sequence. Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.973, signal anchor probability 0.000) with cleavage site probability 0.962 between residues 19 and 20 23613446 Although most of the fasta hits are ATP synthase, the e-value is not significant, also HMMSmart does not pick hits to any domain Similar to Carsonella ruddii ATP synthase gamma subunit atpG SWALL:AAK55899 (EMBL:AF267214) (248 aa) fasta scores: E(): 0.26, 25.87% id in 201 aa, and to Carsonella ruddii ATP synthase gamma subunit atpG SWALL:AAK55899 (EMBL:AF267214) (248 aa) fasta scores: E(): 0.26, 25.87% id in 201 aa 23613448 HMMSmart hit to SM0603, LCCL domain, 4.49e-06; ProfileScan hit to PS50820, LCCL domain profile 23613449 Similarity to mRNA cleavage factor-like protein of Homo sapiens and Arabidopsis thaliana ScanRegExp hit to PS00213, Lipocalin signature Similar to Arabidopsis thaliana mrna cleavage factor subunit-like protein f27b13.60 or at4g29820 SWALL:Q9SZQ4 (EMBL:AL050352) (185 aa) fasta scores: E(): 2.2e-05, 33.7% id in 89 aa, and to Homo sapiens mrna cleavage factor i 25 kDa subunit SWALL:O43809 (EMBL:AJ001810) (227 aa) fasta scores: E(): 1.2e-07, 32.32% id in 198 aa 23613450 Integral membrane protein, similar to Mus musculus cold inducible glycoprotein 30 Pfam match to entry PF01151 GNS1_SUR4, GNS1/SUR4 family, score 32.80, E-value 1.4e-12 Similar to Mus musculus elongation of very long chain fatty acids protein 3 elovl3 or cig30 SWALL:O35949 (EMBL:U97107) (271 aa) fasta scores: E(): 2.1e-18, 31.75% id in 274 aa, and to Drosophila melanogaster putative multipass transmembrane baldspot or noa or cg3971 SWALL:Q9NB55 (EMBL:AF265296) (316 aa) fasta scores: E(): 3.5e-18, 32.05% id in 287 aa 23613451 Similar to Mus musculus tubulin-specific chaperone HMMpfam hit to tubulin binding cofactor A (PF02970); e-value:2.00e-0 Similar to Mus musculus tubulin-specific chaperone a tbcA SWALL:TBCA_MOUSE (SWALL:P48428) (107 aa) fasta scores: E(): 0.024, 33.69% id in 92 aa, and to Homo sapiens tubulin-specific chaperone a tbcA SWALL:TBCA_HUMAN (SWALL:O75347) (107 aa) fasta scores: E(): 0.051, 31.52% id in 92 aa 23613452 Putative acetyltransferase, similar to Drosophila melanogaster Cg14222 protein Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family, score 43.80, E-value 3.8e-09 Similar to Homo sapiens N-terminal acetyltransferase complex ard1 subunit SWALL:AAH08446 (EMBL:AF085355) (178 aa) fasta scores: E(): 1.6e-20, 44.3% id in 158 aa, and to Schizosaccharomyces pombe putative N-terminal acetyltransferase complex protein c16c4.12 spcc16c4.12 SWALL:O74457 (EMBL:AL031535) (180 aa) fasta scores: E(): 1e-19, 42.3% id in 156 aa 23613453 Similar to cold-shock domain protein Pfam match to entry PF00313 CSD, 'Cold-shock' DNA-binding domain, score 44.70, E-value 4.1e-11; HMMSmart hit to SM00357, Cold shock protein domain;ScanRegExp hit to PS00352, 'Cold-shock' domain signature Confirmed by InterPro eMOTIF pattern match Similar to Escherichia coli, and Escherichia coli O157:H7 cold shock-like protein cspg cspg or cspi or b0990 or z1406 or ecs1145 SWALL:AAG55537 (EMBL:D63344) (69 aa) fasta scores: E(): 0.00093, 51.02% id in 49 aa, and to Yersinia enterocolitica major cold shock protein Cspa1 cspa1 SWALL:Q9RIF2 (EMBL:U82821) (70 aa) fasta scores: E(): 0.0029, 48.98% id in 49 aa 23613454 ProfileScan hit to PS50318, Lysine-rich region 23613455 Similar to phenylalanyl-trna synthetases Pfam match to entry PF01409 tRNA-synt_2d, tRNA synthetases class II (F), score 368.30, E-value 8.2e-107; ScanRegExp hit to PS00179, Aminoacyl-transfer RNA synthetases class-II signature 1 Confirmed by InterPro eMOTIF pattern match; HMMTigr hit to TIGR00468 Similar to Saccharomyces cerevisiae phenylalanyl-trna synthetase alpha chain frs2 or yfl022C SWALL:SYFA_YEAST (SWALL:P15625) (502 aa) fasta scores: E(): 1.9e-62, 45.77% id in 461 aa, and to Homo sapiens phenylalanyl-trna synthetase alpha chain farsa or fars or farsL SWALL:SYFA_HUMAN (SWALL:Q9Y285) (508 aa) fasta scores: E(): 2.6e-61, 42% id in 500 aa, and to Mus musculus similar to phenylalanine-trna synthetase-like 0610012a19riK SWALL:AAH06862 (EMBL:BC006862) (508 aa) fasta scores: E(): 1.6e-60, 42.2% id in 500 aa 23613456 Putative integral membrane protein, Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.006, signal anchor probability 0.652)with cleavage site probability 0.002 between residues 29 and 30 PFAM hit to DUF56 family PF01879, 4.2e-02 Similar to Schizosaccharomyces pombe hypothetical 53.1 kDa protein c63.10c in chromosome iii spcc63.10C SWALL:Q9Y7T6 (EMBL:AL049522) (465 aa) fasta scores: E(): 1.9e-06, 26.23% id in 427 aa 23613457 contains signal sequence. Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.362, signal anchor probability 0.635) with cleavage site probability 0.311 between residues 29 and 30 23613458 Putative selenocysteine-specific elongation factor Tu family protein; the similarity exists in the N-terminal half of the protein Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu family, score 53.20, E-value 7.9e-14; ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop) Similar to Homo sapiens selenocysteine-specific elongation factor selB SWALL:SELB_HUMAN (SWALL:P57772) (596 aa) fasta scores: E(): 1.9e-08, 32.51% id in 286 aa, and to Mus musculus selenocysteine-specific elongation factor selb or eefseC SWALL:SELB_MOUSE (SWALL:Q9JHW4) (583 aa) fasta scores: E(): 1.7e-08, 32.15% id in 283 aa 23613459 fasta; TR:AAD17328 (EMBL:AF124604); Homo sapiens; hepatopoietin hpo2; length 125 aa; id=38.54%; ungapped id=38.54%; E()=1.9e-11; 96 aa overlap; query 37-132 aa; subject 16-111 aa. Putative hepatopoietin-like protein, belonging to ERV1/ALR family Similar to Homo sapiens augmenter of liver regeneration gfer or alr or herv1 SWALL:AAD36986 (EMBL:U31176) (125 aa) fasta scores: E(): 1.9e-11, 38.54% id in 96 aa, and to Rattus norvegicus augmenter of liver regeneration gfer or alR SWALL:ALR_RAT (SWALL:Q63042) (125 aa) fasta scores: E(): 2.3e-10, 34.37% id in 96 aa 23613460 RNA polymerase II subunit, similar to several DNA-directed RNA polymerase II Pfam hit to PF02150, RNA polymerases M/15 Kd subunits;4.26e-06; ScanRegExp hit to PS01030, RNA polymerases M / 15 Kd subunits signature Similar to Drosophila melanogaster DNA-directed RNA polymerase ii 15.1 kDa polypeptide rpii15 SWALL:RPB9_DROME (SWALL:P36958) (129 aa) fasta scores: E(): 1.6e-10, 42.47% id in 113 aa, and to Homo sapiens DNA-directed RNA polymerase ii 14.5 kDa polypeptide polr2I SWALL:RPB9_HUMAN (SWALL:P36954) (125 aa) fasta scores: E(): 1.3e-09, 41.22% id in 114 aa, and to Schizosaccharomyces pombe DNA-directed RNA polymerase ii 13.2 kDa polypeptide rpb9 or spapyug7.04C SWALL:RPB9_SCHPO (SWALL:O74635) (113 aa) fasta scores: E(): 5.3e-05, 32.2% id in 118 aa 23613461 Plasmodium falciparum hypothetical protein with bromodomain Pfam match to entry PF00439 bromodomain, Bromodomain, score 37.10, E-value 2.3e-09; HMMSmart hit to SM00297, bromo domain Similar to Plasmodium falciparum hypothetical 534.1 kDa protein pfc0425w, mal3p3.18 SWALL:O77336 (EMBL:Z98547) (4550 aa) fasta scores: E(): 1.3e-30, 23.17% id in 2403 aa, and to Plasmodium falciparum hypothetical 280.9 kDa protein pfc1015c, mal3p7.34 SWALL:O97298 (EMBL:AL034559) (2340 aa) fasta scores: E(): 2.6e-22, 23.4% id in 2179 aa 23613462 Possible phosphatidylinositol-4-phosphate 5-kinase Pfam hit to PF01504,Phosphatidylinositol-4-phosphate 5-Kinase; Pfam hit to PF00036, EF hand;HMMSmart hit to SM00330, Phosphatidylinositol phosphate kinases; ScanRegExp hit to PS00018, EF-hand calcium-binding domain; ScanRegExp hit to PS00038, Myc-type,'helix-loop-helix' dimerisation domain signature 23613463 putative chromatin assembly factor 1 protein with 6 WD40 repeat domains Pfam match to entry PF00400 WD40, WD domain, G-beta repeat, score 23.80, E-value 0.0042;HMMSmart hit to SM00320, WD40 repeats Similar to Arabidopsis thaliana wd-40 repeat protein msi1 msi1 or at5g58220 or mck7.10 SWALL:BAA96914 (EMBL:AF016846) (424 aa) fasta scores: E(): 1.3e-41, 33.65% id in 413 aa, and to Lycopersicon esculentum wd-40 repeat protein Msi1 msi1 SWALL:MSI1_LYCES (SWALL:O22466) (424 aa) fasta scores: E(): 9.5e-41, 32.93% id in 413 aa, and to Drosophila melanogaster chromatin assembly factor 1 p55 subunit caf1 or cg4236 SWALL:CAF1_DROME (SWALL:Q24572) (430 aa) fasta scores: E(): 5.7e-38, 32.16% id in 429 aa, and to Gallus gallus chromatin assembly factor 1 p48 subunit SWALL:Q9W7I5 (EMBL:AF097750) (425 aa) fasta scores: E(): 3.1e-37, 31.42% id in 420 aa 23613464 Possible transcription initiation factor TFIIB Pfam hit to PF00097, Zinc finger, C3HC4 type (RING finger), Pfam hit to PF00382, Transcription factor TFIIB repeat Similar to SWALL:TF2B_ARATH (SWALL:) (312 aa) fasta scores: E(): 2.1e-16, 26.04% id in 311 aa, and to Saccharomyces cerevisiae transcription initiation factor iib sua7 or ypr086w or p9513.4 SWALL:TF2B_YEAST (SWALL:P29055) (345 aa) fasta scores: E(): 1.1e-12, 27.65% id in 311 aa 23613465 Similar to Homo sapiens protein CGI-137 SWALL:AAH07349 (EMBL:AF151895) (172 aa) fasta scores: E(): 6.2e-10, 33.51% id in 182 aa, and to Caenorhabditis elegans hypothetical protein E02h1.6 in chromosome ii e02h1.6 SWALL:CAA87383 (EMBL:Z47075) (182 aa) fasta scores: E(): 1.7e-06, 28.9% id in 173 aa, and to Schizosaccharomyces pombe conserved hypothetical protein spcc830.11C SWALL:Q9UU88 (EMBL:AL109850) (175 aa) fasta scores: E(): 1.7e-07, 32.6% id in 184 aa 23613466 Similar to several kinesin-like proteins Pfam match to entry PF00225 kinesin, Kinesin motor domain, score 381.70, E-value 7.5e-111; ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop); HMMSmart hit to SM00129, Kinesin motor, catalytic domain; ProfileScan hit to PS50067, Kinesin motor domain profile 23613468 Pfam match to entry PF00004 AAA, ATPase family associated with various cellular activities (AAA), score 18.30, E-value 0.00011; HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities; ScanRegExp hit to PS00017, ATP/GTP-binding site motif A (P-loop) Similar to Drosophila melanogaster activator 1 140 kDa subunit gnf1 or cg1119 SWALL:AC15_DROME (SWALL:P35600) (986 aa) fasta scores: E(): 5.4e-10, 25.39% id in 378 aa, and to Homo sapiens activator 1 140 kDa subunit rfc1 or rfc140 SWALL:AC15_HUMAN (SWALL:P35251) (1147 aa) fasta scores: E(): 7.5e-08, 24.47% id in 384 aa, and to Plasmodium falciparum replication factor c subunit 1 rfc1 SWALL:Q9GQW6 (EMBL:AF139827) (904 aa) fasta scores: E(): 2.7e-14, 25.27% id in 740 aa 23613469 TMMHMM2.0 prdicts three putative transmembrane domains near the N-terminus 23613470 Putative UMP-CMP kinase, alternative start site could be methionine approximately 100 amino acids downstream; similar to Cryptosporidium parvum ump kinase umpK TR:O96498 (EMBL:AF067966) Pfam match to entry PF00406 adenylatekinase, Adenylate kinase, score 45.10, E-value 1.6e-11; Pfam hit to PF00406, Adenylate kinase;ScanRegExp hit to PS00113, Adenylate kinase signature Similar to Dictyostelium discoideum cytidylate kinase ctpS SWALL:KCY_DICDI (SWALL:P20425) (194 aa) fasta scores: E(): 1.1e-10, 29.41% id in 272 aa 23613472 gene finder predicts a larger protein with weak similarity to a haem lyase protein but the exon sequence is not convincing with a stretch of IYIYIYs 23613473 splicing pattern uncertain 23613474 Similar to Schizosaccharomyces pombe hypothetical protein c119.18 spbc119.18 SWALL:Q96VG1 (EMBL:AL022117) (69 aa) fasta scores: E(): 1.3e-06, 39.68% id in 63 aa, and to Homo sapiens protein 15e1.1 15e1.1 SWALL:15E1_HUMAN (SWALL:O43715) (76 aa) fasta scores: E(): 0.00046, 38% id in 50 aa, and to Mus musculus protein 15e1.1 15e1.1 SWALL:Q9D8Z2 (EMBL:AK007514) (76 aa) fasta scores: E(): 0.00054, 38% id in 50 aa 23613475 Originally annotated as Plasmodium falciparum; conserved hypothetical protein but pfam match and other evidences suggest that it is a putative deoxyribonuclease; earlier start site possible to make a 412 aa protein Pfam match to entry PF01026 TatD_DNase, TatD related DNase, score 117.30, E-value 2.9e-31 Similar to Plasmodium falciparum conserved hypothetical protein, upf0006 family mal1p3.01 SWALL:Q9U0N6 (EMBL:AL031746) (412 aa) fasta scores: E(): 3.7e-150, 100% id in 412 aa, and to Saccharomyces cerevisiae putative deoxyribonuclease ybl055c ybl055c or ybl0512 or ybl0511 SWALL:YBF5_YEAST (SWALL:P34220) (418 aa) fasta scores: E(): 2.5e-19, 30.47% id in 397 aa 23613476 contains possible signal sequence. Signal peptide predicted SignalP 2.0 HMM (Signal peptide probabilty 0.640, signal anchor probability 0.357) with cleavage site probability 0.504 between residues 27 and 28. ScanRegExp hit to PS00867, Carbamoyl-phosphate synthase subdomain signature 2 23613477 Putative ABC transporter Pfam match to entry PF00005 ABC_tran, ABC transporter, score 45.00, E-value 1.7e-09; HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities; ScanRegExp hit to PS00211, ABC transporters family signature Similar to Schizosaccharomyces pombe ATP-binding cassette transporter abc1 abc1 or spac9e9.12C SWALL:ABC1_SCHPO (SWALL:Q92337) (1427 aa) fasta scores: E(): 4.2e-08, 21.46% id in 1146 aa 23613478 Conserved hypothetical membrane protein, Similarity to P. falciparum chromosome 2 predicted integral membrane protein (PFB0110W). Signal anchor predicted SignalP 2.0 HMM (Signal peptide probabilty 0.145, signal anchor probability 0.851) with cleavage site probability 0.048 between residues 25 and 26 Similar to Plasmodium falciparum predicted integral membrane protein pfb0110W SWALL:O96126 (EMBL:AE001373) (255 aa) fasta scores: E(): 1.4e-13, 35.26% id in 190 aa 23613479 Plasmodium falciparum hypothetical protein. Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.624, signal anchor probability 0.000) with cleavage site probability 0.200 between residues 28 and 29 Similar to Plasmodium falciparum hypothetical 21.9 kDa protein mal1p3.05 SWALL:Q9U0N2 (EMBL:AL031746) (188 aa) fasta scores: E(): 2.1e-66, 100% id in 188 aa 23613480 P. falciparum glutamic acid-rich protein; Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.869, signal anchor probability 0.050) with cleavage site probability 0.208 between residues 23 and 24 Similar to Plasmodium falciparum hypothetical GarP protein garP SWALL:Q9U0N1 (EMBL:AL031746) (673 aa) fasta scores: E(): 8.1e-140, 100% id in 673 aa 23613481 moderately similar to SWALL:Q9N894 (EMBL:AL360354) Plasmodium vivax Pvstp1 protein (826 aa) Similar to Plasmodium falciparum hypothetical 192.3 kDa protein mal1p3.07 SWALL:Q9U0N0 (EMBL:AL031746) (1555 aa) fasta scores: E(): 0, 100% id in 1555 aa, and to Plasmodium vivax Pvstp1 protein pvstp1 SWALL:Q9N894 (EMBL:AL360354) (826 aa) fasta scores: E(): 4.2e-14, 28.16% id in 355 aa 23613482 splicing: 2 exons predicted but alternative(s) exist(s) Similar to Plasmodium falciparum hypothetical 64.5 kDa protein mal1p3.08 SWALL:Q9U0M9 (EMBL:AL031746) (546 aa) fasta scores: E(): 7.1e-176, 100% id in 546 aa 23613483 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.009, signal anchor probability 0.990) with cleavage site probability 0.007 between residues 29 and 30 Similar to Plasmodium falciparum hypothetical 71.0 kDa protein mal1p3.09 SWALL:Q9U0M8 (EMBL:AL031746) (584 aa) fasta scores: E(): 9.1e-212, 100% id in 584 aa 23613484 Similar to Plasmodium falciparum hypothetical 53.7 kDa protein mal1p3.10 SWALL:Q9U0M7 (EMBL:AL031746) (431 aa) fasta scores: E(): 2.5e-138, 100% id in 431 aa 23613485 Similar to Plasmodium falciparum hypothetical 10.1 kDa protein mal1p3.11 SWALL:Q9U0M6 (EMBL:AL031746) (81 aa) fasta scores: E(): 2.4e-30, 100% id in 81 aa 23613486 splicing: predicted to have two exons but could be spliced to downstream orf Similar to Plasmodium falciparum hypothetical 108.2 kDa protein mal1p3.12 SWALL:Q9U0M5 (EMBL:AL031746) (954 aa) fasta scores: E(): 0, 100% id in 954 aa 23613487 hypothetical protein with RPT_1 repeat domain; RPT_1 domain starts at position 478 and ends at position 738; the E-value for the Prospero:RPT_1 domain is 1.068871e-25 as determined by prospero programme Similar to Plasmodium falciparum partial, hypothetical protein, Mal1p3.14 mal1p3.14 SWALL:Q9U0M3 (EMBL:AL031746) (262 aa) fasta scores: E(): 1.3e-64, 84.05% id in 232 aa, and to Plasmodium vivax Pvstp1 protein pvstp1 SWALL:Q9N894 (EMBL:AL360354) (826 aa) fasta scores: E(): 3e-15, 28.8% id in 368 aa 23613488 hypothetical protein with RPT_1 repeat domain; RPT_1 domain starts at position 478 and ends at position 738; the E-value for the Prospero:RPT_1 domain is 1.068871e-25 as determined by prospero programme Similar to Plasmodium falciparum partial, hypothetical protein, Mal1p3.14 mal1p3.14 SWALL:Q9U0M3 (EMBL:AL031746) (262 aa) fasta scores: E(): 1.3e-64, 84.05% id in 232 aa, and to Plasmodium vivax Pvstp1 protein pvstp1 SWALL:Q9N894 (EMBL:AL360354) (826 aa) fasta scores: E(): 3e-15, 28.8% id in 368 aa 23613489 Similar to Plasmodium falciparum protein with DNAJ domain and also to heat-shock proteins Pfam match to entry PF00226 DnaJ, DnaJ domain, score 126.30, E-value 5.5e-34; Pfam match to entry PF01556 DnaJ_C, DnaJ C terminal region, score 42.90, E-value 7e-09; HMMSmart hit to SM00271, DnaJ molecular chaperone homology domain; ScanRegExp hit to PS00636, Nt-dnaJ domain signature, confirmed by InterPro eMOTIF pattern match;eProfileScan hit to PS50076, dnaJ domain profile Similar to Plasmodium falciparum protein with DNAJ domain, dnj1/sis1 family pfb0595W SWALL:O96212 (EMBL:AE001405) (328 aa) fasta scores: E(): 9e-57, 45.12% id in 328 aa, and to Plasmodium falciparum protein with DNAJ domain pfb0090C SWALL:O96123 (EMBL:AE001370) (354 aa) fasta scores: E(): 3.2e-39, 50% id in 340 aa, and to Arabidopsis thaliana putative heat shock protein t16o11.15 SWALL:Q9SR91 (EMBL:AC010871) (323 aa) fasta scores: E(): 5.6e-36, 37.23% id in 333 aa 23613490 hypothetical protein, weakly related to erythrocyte binding proteins from P. falciparum; Blastp resullts indicate this protein is similar to erythrocyte binding proteins whereas fasta resullts show similarities to Fibrinogen binding protein / clumping factor from bacterial origin. Because of lack of conclusive evidence it is annotated as a hypothetical protein; possibilities exist for more than 1 protein coded by these exons rather than one large protein Similar to Staphylococcus aureus clumping factor b precursor clfB SWALL:O86476 (EMBL:AJ224764) (913 aa) fasta scores: E(): 3.5e-20, 24.31% id in 695 aa, and to Staphylococcus aureus fibrinogen-binding protein a, clumping factor clfa or sa0742 SWALL:Q99VJ4 (EMBL:AP003131) (989 aa) fasta scores: E(): 1.2e-19, 23.57% id in 649 aa 23613491 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.687, signal anchor probability 0.232) with cleavage site probability 0.431 between residues 24 and 25 23613492 Also moderately similar to P. falciparum mature parasite-infected erythrocyte surface antigen (mesa); The first exon may extend 12 more amino acids as a potential splice-donor site exits; Contains repeats, C-terminal domain virtually identical to SWALL:O97462 (EMBL:AL034559); Plasmodium falciparum; pfc1075w protein Pfam match to entry PF00226 DnaJ, DnaJ domain, score 68.40, E-value 1.6e-16 Similar to Plasmodium falciparum pfc1075w protein pfc1075w or pfb0980W SWALL:O97462 (EMBL:AL034559) (282 aa) fasta scores: E(): 8.5e-51, 92.9% id in 282 aa, and to Plasmodium falciparum mature-parasite-infected erythrocyte surface antigen mesA SWALL:Q25920 (EMBL:M69183) (1510 aa) fasta scores: E(): 4e-28, 29.39% id in 1218 aa 23613493 2 transmembrane domains predicted Similar to Plasmodium falciparum predicted integral membrane protein pfb0985C SWALL:O96287 (EMBL:AE001431) (186 aa) fasta scores: E(): 3.3e-59, 93.01% id in 186 aa, and to Plasmodium falciparum hypothetical membrane protein, pfc1080c pfc1080c, mal3p7.47 SWALL:O97307 (EMBL:AL034559) (231 aa) fasta scores: E(): 5.5e-50, 81.91% id in 188 aa 23613494 Similar to Plasmodium falciparum pfc1085c protein pfc1085c or pfb0990C TR:O97474 (EMBL:AL034559) except in the internal repeat region. Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.712, signal anchor probability 0.000) with cleavage site probability 0.405 between residues 23 and 24 Similar to Plasmodium falciparum pfc1085c protein pfc1085c or pfb0990C SWALL:O97474 (EMBL:AL034559) (230 aa) fasta scores: E(): 1.1e-21, 44.66% id in 347 aa, and to Plasmodium falciparum hypothetical 15.6 kDa protein pfb0965C SWALL:O96285 (EMBL:AE001430) (136 aa) fasta scores: E(): 4.8e-20, 61.48% id in 135 aa 36329003042 Possible pseudogene; Similar to TR:O97308 (EMBL:AL034559); Plasmodium falciparum; Pfc1090W protein family but splicing not possible to obtain full length protein; alternative gene model possibilities exists with 2 separate proteins being coded by this region of DNA; fasta; TR:O97308 (EMBL:AL034559); Plasmodium falciparum; Pfc1090W protein; pfc1090W; length 309 aa; id=53.43%; ungapped id=58.6%; E()=1.1e-21; 204 aa overlap; query 4-191 aa; subject 108-309 aa. hypothetical protein; could be a part of the preceding ORF to form a full protein similar to Pfc1090w but splicing is not possible to obtain right protein; could be a pseudogene; Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.115, signal anchor probability 0.839) with cleavage site probability 0.060 between residues 25 and 26 pseudogene, P. falciparum-specific gene family 36329003043 Var-like pseudogene; fasta; TR:Q9NFB4 (EMBL:AL031747); Plasmodium falciparum; var-like protein, Mal1p4.03; mal1p4.03; length 1327 aa; id=47.05%; ungapped id=53.78%; E()=3.3e-16; 136 aa overlap; query 4-131 aa; subject 1075-1201 aa 23613495 Predicted secreted protein family, conserved in P. falciparum, with 1 predicted transmembrane domain Similar to Plasmodium falciparum predicted secreted protein pfb0070W SWALL:O96119 (EMBL:AE001369) (156 aa) fasta scores: E(): 2.2e-15, 56.52% id in 92 aa 36329003045 STEVOR fragment; similarity to Plasmodium falciparum stevor 3d73-2; length 296 aa; id=79.03%; ungapped id=79.03%; E()=1.3e-16; 62 aa overlap; query 1-62 aa; subject 1-62 aa 23613496 Similar to Plasmodium falciparum rifin. Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.951, signal anchor probability 0.005) with cleavage site probability 0.284 between residues 23 and 24 Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 427.60, E-value 2.5e-125 Similar to Plasmodium falciparum rifin pfb1040W SWALL:O96293 (EMBL:AE001433) (345 aa) fasta scores: E(): 1.7e-35, 49.55% id in 339 aa 23613497 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.011, signal anchor probability 0.667) with cleavage site probability 0.008 between residues 24 and 25 23613499 hypothetical protein, possibly conserved in P. falciparum, weakly similar to Plasmodium vivax Pvstp1 protein Similar to Plasmodium falciparum hypothetical 192.3 kDa protein mal1p3.07 SWALL:Q9U0N0 (EMBL:AL031746) (1555 aa) fasta scores: E(): 6.1e-50, 30.94% id in 1690 aa, and to Plasmodium vivax Pvstp1 protein pvstp1 SWALL:Q9N894 (EMBL:AL360354) (826 aa) fasta scores: E(): 2.2e-22, 24.87% id in 812 aa 23613501 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.006, signal anchor probability 0.985) with cleavage site probability 0.002 between residues 29 and 30 23613502 Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 516.40, E-value 1.7e-151 Similar to Plasmodium falciparum rifin pfb0030C SWALL:O96112 (EMBL:AE001367) (370 aa) fasta scores: E(): 4.8e-82, 64.05% id in 370 aa, and to Plasmodium falciparum rifin pfb1010W SWALL:O96289 (EMBL:AE001432) (368 aa) fasta scores: E(): 1.5e-67, 54.86% id in 370 aa 23613503 Similar to Plasmodium falciparum rifins Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 536.80, E-value 1.5e-157 Similar to Plasmodium falciparum rifin pfb1040W SWALL:O96293 (EMBL:AE001433) (345 aa) fasta scores: E(): 4.1e-73, 68.69% id in 345 aa 23613504 Similar to Plasmodium falciparum StevoR isoform troph alpha Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 384.80, E-value 1e-112 Similar to Plasmodium falciparum stevor pfc1105w, mal3p7.52 SWALL:Q9U5M0 (EMBL:AL034559) (301 aa) fasta scores: E(): 1e-67, 67.42% id in 307 aa 36329003055 Possible var-related pseudogene 23613505 Similar to Plasmodium falciparum Rifins Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 445.50, E-value 1.3e-130 Similar to Plasmodium falciparum RifiN, mal1p4.04 rifiN SWALL:Q9NFB3 (EMBL:AL031747) (372 aa) fasta scores: E(): 1.7e-65, 55.38% id in 381 aa 23613506 Pfam match to entry PF03011 PFEMP1, score 167.00, E-value 3.2e-46 Similar to Plasmodium falciparum var pfc1120c, mal3p7.55 SWALL:O97312 (EMBL:AL034559) (2169 aa) fasta scores: E(): 3.1e-154, 46.4% id in 2310 aa 23613029 Similar to Plasmodium falciparum variant-specific surface protein var-2 TR:Q26033 (EMBL:L40609) (2664 aa) fasta scores: E(): 2.1e-94, 38.066% id in 2782 aa 36329003059 VAR fragment 36329003060 Similar to Plasmodium falciparum rifin pfb1040W TR:O96293 (EMBL:AE001433) (345 aa) fasta scores: E(): 1.1e-50, 53.161% id in 348 aa. Contains nonsense mutations at apparent start position for exon 2 23613030 Similar to Plasmodium falciparum rifin pfb0030C TR:O96112 (EMBL:AE001367) (370 aa) fasta scores: E(): 3.3e-62, 53.125% id in 384 aa 1 probable transmembrane helix predicted for by TMHMM2.0 at aa 332-354 23613031 Similar to Plasmodium falciparum rifin pfb1005W TR:O96288 (EMBL:AE001432) (316 aa) fasta scores: E(): 8.3e-52, 54.574% id in 317 aa 2 probable transmembrane helices predicted for by TMHMM2.0 at aa 122-144 and 271-293 36329003063 Apparent single frameshift in exon II 36329003064 RIF fragment 23613032 Similar to Plasmodium falciparum mature parasite-infected erythrocyte surface antigen TR:Q06166 (EMBL:AF056936) (1661 aa) fasta scores: E(): 3.6e-144, 81.331% id in 1698 aa Identical to pfemp2 (EMBL:AF056936) except in internal repeat structures 23613033 Similar to Plasmodium falciparum Mal3p8.10 protein mal3p8.10 TR:Q9Y012 (EMBL:AL034560) (587 aa) fasta scores: E(): 2.6e-71, 39.925% id in 536 aa; contains a SMART:STYKc domain (Ser/Thr/Tyr kinase) at position 237-592, E-value = 0.00086 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 0.992) with cleavage site probability 0.000 between residues 17 and 18 23613034 1 probable transmembrane helix predicted for by TMHMM2.0 at aa 44-61 23613035 Similar to Arabidopsis thaliana putative heat shock protein f23h11.4 TR:Q9XIF5 (EMBL:AC007258) (331 aa) fasta scores: E(): 7e-41, 41.463% id (43.038% ungapped) in 328 aa overlap (80-398:4-328); also similar to Plasmodium falciparum protein with DNAJ domain, dnj1/sis1 family pfb0595W TR:O96212 (EMBL:AE001405) (328 aa) fasta scores: E(): 2.5e-79, 60.802% id (61.180% ungapped) in 324 aa overlap (80-401:4-327) 1 probable transmembrane helix predicted for by TMHMM2.0 at aa 13-32 23613036 Weak similarity to Pasteurella multocida fima or pm0926 TR:Q9CMA8 (EMBL:AE006132) (366 aa) fasta scores: E(): 2.4e-06, 34.426% id in 122 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.989, signal anchor probability 0.000) with cleavage site probability 0.564 between residues 23 and 24 3 probable transmembrane helices predicted for by TMHMM2.0 at aa 4-21, 357-379 and 389-407 23613037 Similar to Plasmodium falciparum skeleton binding protein 1 sbp1 TR:Q9NFF5 (EMBL:AJ387723) (338 aa) fasta scores: E(): 3.2e-88, 95.107% id (96.285% ungapped) in 327 aa overlap (1-323:1-327) 1 probable transmembrane helix predicted for by TMHMM2.0 at aa 216-238 23613038 Similar to Plasmodium falciparum interspersed repeat antigen TR:Q25884 (EMBL:M17877) (700 aa) fasta scores: E(): 7.5e-89, 75.000% id in 828 aa 23613039 Similar to Plasmodium falciparum rhoptry-associated protein 2 rap2 TR:Q9U433 (EMBL:AF205279) (398 aa) fasta scores: E(): 1.3e-68, 46.734% id in 398 aa Signal peptide predicted for by SignalP 2.0 HMM (Signal peptide probabilty 0.998, signal anchor probability 0.001) with cleavage site probability 0.736 between residues 22 and 23 1 probable transmembrane helix predicted for by TMHMM2.0 at aa 5-22 23613040 Similar to Plasmodium falciparum rhoptry-associated protein 2 rap2 TR:Q9U433 (EMBL:AF205279) (398 aa) fasta scores: E(): 7.6e-155, 100.000% id in 396 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.993, signal anchor probability 0.000) with cleavage site probability 0.848 between residues 21 and 22 23613041 Weak similarity to Drosophila melanogaster protein cdc27 or cg8610 TR:Q9VS37 (EMBL:AE003559) (900 aa) fasta scores: E(): 7.4e-07, 21.600% id in 375 aa 23613042 Weak similarity to Plasmodium falciparum pfc0150w, mal3p1.12 protein TR:O77317 (EMBL:Z97348) (1156 aa) fasta scores: E(): 8e-13, 23.077% id in 598 aa 23613044 Weak similarity to Amsacta moorei entomopoxvirus Amv156 TR:Q9EMP3 (EMBL:AF250284) (1238 aa) fasta scores: E(): 1.4e-13, 22.034% id in 1298 aa 23613046 Weak similarity to Arabidopsis thaliana putative 22 kDa peroxisomal membrane protein t26i20.2 TR:O82324 (EMBL:AC005396) (252 aa) fasta scores: E(): 2.5e-07, 25.628% id in 199 aa 5 probable transmembrane helices predicted for by TMHMM2.0 at aa 276-298, 319-341, 356-378, 398-415 and 419-441 23613048 1 probable transmembrane helix predicted for by TMHMM2.0 at aa 574-596 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.808, signal anchor probability 0.189) with cleavage site probability 0.762 between residues 25 and 26 23613049 Asparagine-rich Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.892, signal anchor probability 0.079) with cleavage site probability 0.545 between residues 21 and 22 2 probable transmembrane helices predicted by TMHMM2.0 at aa 450-472 and 567-589 23613050 Asparagine-rich 23613052 Weak similarity to mitochondrial import inner membrane translocase subunit from several organism; e.g. similar to Saccharomyces cerevisiae mitochondrial import inner membrane translocase subunit tim10 mrs11 or tim10 or yhr005c-a or yhr005bC SW:IM10_YEAST (P87108) (93 aa) fasta scores: E(): 0.00046, 26.506% id in 83 aa 23613053 Similar to Toxoplasma gondii large ribosomal protein l28 precursor rpl28 TR:O77465 (EMBL:AF038927) (272 aa) fasta scores: E(): 8e-19, 45.000% id in 140 aa 2 probable transmembrane helices predicted for by TMHMM2.0 at aa 13-32 and 72-94 23613054 Similar to Arabidopsis thaliana 4-diphosphocytidyl-2c-methyl-D-erythritol kinase ispE TR:Q9GI18 (EMBL:AF288615) (383 aa) fasta scores: E(): 1.5e-08, 29.692% id in 357 aa Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.155, signal anchor probability 0.661) with cleavage site probability 0.051 between residues 27 and 28 1 probable transmembrane helix predicted by TMHMM2.0 at aa 7-26 23613055 Asparagine-rich 23613056 Similar to Oryzias latipes splicing factor arginine/serine rich 2 sfrs2 TR:Q9DGK5 (EMBL:AF288041) (211 aa) fasta scores: E(): 5.2e-14, 37.190% id (42.857% ungapped) in 242 aa overlap (13-253:1-211); match to SMART:RRN (RNA recognition motif) at position 13-86, E-value = 1.4e-22 Similar to Homo sapiens tls-associated serine-arginine protein 2 TR:AAH05039 (EMBL:BC005039) (262 aa) fasta scores: E(): 1.7e-14, 33.835% id in 266 aa 23613057 Similar to Toxoplasma gondii actin depolymerizing factor TR:O15902 (EMBL:U62146) (118 aa) fasta scores: E(): 3.3e-13, 38.017% id in 121 aa 23613058 Similar to Drosophila melanogaster Cg1973 protein cg1973 TR:Q9VAH7 (EMBL:AE003771) (873 aa) fasta scores: E(): 5.1e-16, 23.553% id in 743 aa 23613059 Similar to Plasmodium falciparum unconventional myosin pfm-b TR:Q9U3U9 (EMBL:AF222716) (801 aa) fasta scores: E(): 0, 99.376% id in 801 aa 23613061 Similar to Cyanophora paradoxa 60S ribosomal protein l31 rpl31 SW:RL31_CYAPA (Q9XGL4) (119 aa) fasta scores: E(): 7.4e-20, 55.238% id in 105 aa 23613062 1 probable transmembrane helix predicted by TMHMM2.0 at aa 16-35 23613063 Similar to Plasmodium falciparum Pfatpase3 TR:Q9U0N7 (EMBL:X65740) (1903 aa) fasta scores: E(): 0, 99.160% id (99.736% ungapped) in 1904 aa overlap (496-2393:5-1903). Also similar to Plasmodium yoelii p-type ATPase TR:Q9XXW1 (EMBL:AB018798) (1877 aa) fasta scores: E(): 6.6e-95, 47.425% id in 2427 aa Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 1.000) with cleavage site probability 0.000 between residues 35 and 36 12 probable transmembrane helices predicted by TMHMM2.0 at aa 20-37, 98-120, 133-152,585-605, 844-866, 886-905, 917-939, 2129-2151, 2196-2218,2246-2268, 2275-2297 and 2358-2380 23613064 Similar to Arabidopsis thaliana putative zinc finger protein pmZ TR:Q9XH76 (EMBL:AF139098) (186 aa) fasta scores: E(): 1.7e-12, 37.500% id in 136 aa 23613065 Signal peptide predicted for MAL5P1.46 by SignalP 2.0 HMM (Signal peptide probabilty 0.991, signal anchor probability 0.008) with cleavage site probability 0.963 between residues 20 and 21 23613067 Similar to Arabidopsis thaliana RNA helicase TR:Q9LVB7 (EMBL:AB019235) (671 aa) fasta scores: E(): 3.9e-48, 35.566% id in 627 aa 23613068 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.987, signal anchor probability 0.000) with cleavage site probability 0.729 between residues 21 and 22 1 probable transmembrane helix predicted by TMHMM2.0 at aa 249-271 23613069 Similar to Homo sapiens 2-oxoisovalerate dehydrogenase beta subunit, mitochondrial precursor bckdhB SW:ODBB_HUMAN (P21953) (392 aa) fasta scores: E(): 7.8e-87, 61.043% id in 326 aa 23613071 Similar to Plasmodium falciparum Pfc0425W protein pfc0425W TR:O77336 (EMBL:Z98547) (4550 aa) fasta scores: E(): 1.5e-22, 21.644% id in 4477 aa 23613072 1 probable transmembrane helix predicted by TMHMM2.0 at aa 20-42 23613073 Conserved low complexity repeats with other plasmodium genes 4 probable transmembrane helices predicted by TMHMM2.0 at aa 1223-1241, 1262-1281, 2835-2857 and 2897-2919 23613074 Asparagine-rich 23613075 Similar to Homo sapiens actin-related protein baf53A TR:O96019 (EMBL:AB015907) (429 aa) fasta scores: E(): 2.3e-11, 23.370% id in 368 aa; matches SMART:Actin, E-value = 1e-14 23613076 Weak similarity to Homo sapiens similar to solute carrier family 35 TR:AAH05136 (EMBL:BC005136) (220 aa) fasta scores: E(): 3e-05, 25.166% id in 151 aa 9 probable transmembrane helices predicted by TMHMM2.0 at aa 64-86, 101-118, 142-164,174-191, 411-433, 443-462, 534-556, 561-583 and 590-608 23613077 Weak similarity to Plasmodium falciparum hypothetical 118.9 kDa protein pfb0765W TR:O96246 (EMBL:AE001417) (980 aa) fasta scores: E(): 8.8e-06, 22.076% id in 684 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.848, signal anchor probability 0.009) with cleavage site probability 0.489 between residues 15 and 16 23613078 Similar to Mus musculus DNA mismatch repair protein msh6 or gtmbP SW:MSH6_MOUSE (P54276) (1358 aa) fasta scores: E(): 6.9e-59, 28.214% id in 1198 aa 23613080 Similar to Plasmodium falciparum hypothetical 78.6 kDa protein pfb0680W TR:O96229 (EMBL:AE001410) (665 aa) fasta scores: E(): 5.8e-13, 26.969% id in 508 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.881, signal anchor probability 0.000) with cleavage site probability 0.840 between residues 21 and 22 4 probable transmembrane helices predicted for by TMHMM2.0 at aa 515-534, 547-566, 652-674 and 686-708 23613081 Similar to Oryza sativa ubiquitin-like protein Smt3 SW:SMT3_ORYSA (P55857) (100 aa) fasta scores: E(): 1.2e-15, 50.526% id in 95 aa 23613083 1 probable transmembrane helix predicted by TMHMM2.0 at aa 15-37 23613084 Similar to Homo sapiens rpl24 TR:AAK26249 (EMBL:AF212226) (163 aa) fasta scores: E(): 3.6e-26, 49.689% id in 161 aa 23613085 Similar to Plasmodium falciparum transcription initiation factor tfiid tbP SW:TF2D_PLAFA (P32086) (228 aa) fasta scores: E(): 7.3e-78, 100.000% id in 228 aa Similar to Plasmodium falciparum tata-binding protein tbP TR:AAD55768 (EMBL:AF177280) (228 aa) fasta scores: E(): 7.3e-78, 100.000% id in 228 aa 23613086 Low complexity; Weak similarity to Plasmodium falciparum protein with DNAJ domain pfb0925W TR:O96277 (EMBL:AE001426) (657 aa) fasta scores: E(): 3e-07, 27.891% id in 294 aa 23613087 1 probable transmembrane helix predicted by TMHMM2.0 at aa 9-31 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.386, signal anchor probability 0.613) with cleavage site probability 0.269 between residues 30 and 31 23613088 1 probable transmembrane helix predicted by TMHMM2.0 at aa 966-988 23613089 Asparagine-rich 23613090 Contains SMART TBC domain (SM0164). Widespread domain present in Gyp6 and Gyp7, possibly could act as a GTP-activator 23613092 Similar to Arabidopsis thaliana F6d8.20 f6d8.20 TR:Q9SSR0 (EMBL:AC008016) (309 aa) fasta scores: E(): 5.3e-13, 37.162% id in 148 aa 6 probable transmembrane helices predicted by TMHMM2.0 at aa 336-358, 464-486, 521-543, 550-572, 577-599 and 681-703 23613094 Similar to Rattus norvegicus 60S ribosomal protein l4 rpl4 or rpl1 SW:RL4_RAT (P50878) (421 aa) fasta scores: E(): 1.2e-69, 49.754% id in 406 aa Gene model modified and verified, using data from the proteomics study, lead by M. Mann and Henk Stunnenberg 23613095 Similar to Plasmodium falciparum subtilisin-like protease precursor sub-1 or pfsub-1 TR:O61142 (EMBL:AJ002594) (690 aa) fasta scores: E(): 1.1e-23, 26.418% id in 723 aa 23613096 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.028, signal anchor probability 0.924) with cleavage site probability 0.009 between residues 22 and 23 23613098 Similar to Plasmodium falciparum subtilisin-like protease precursor sub-1 or pfsub-1 TR:O61142 (EMBL:AJ002594) (690 aa) fasta scores: E(): 0, 99.710% id in 690 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.894, signal anchor probability 0.106) with cleavage site probability 0.818 between residues 25 and 26 23613099 Similar to Schizosaccharomyces pombe cell differentiation protein rcd1 or spac29b12.06C TR:Q92368 (EMBL:D87956) (283 aa) fasta scores: E(): 3.6e-57, 66.547% id in 278 aa Asparagine-rich protein; ProfileScan hit to PS50321, Asparagine-rich region 23613100 Similar to Caenorhabditis elegans coded for by c. elegans cdna yk53d12.5 f59e12.5 TR:O01894 (EMBL:AF003386) (527 aa) fasta scores: E(): 1.7e-10, 27.019% id in 359 aa 23613101 Weak similarity to Plasmodium falciparum Pfc0760C protein pfc0760C TR:O77384 (EMBL:Z98551) (3394 aa) fasta scores: E(): 2.3e-27, 24.341% id in 1290 aa 23613103 Signal peptide predicted by SignalP FT 2.0 HMM (Signal peptide probabilty 0.856, signal anchor probability 0.138) with cleavage site probability 0.747 between residues 21 and 22 1 probable transmembrane helix predicted by TMHMM2.0 at aa 328-347 23613104 Weak similarity to Saccharomyces cerevisiae hypothetical 123.6 kDa protein in por2-cox5b intergenic region yil112W SW:YIL2_YEAST (P40480) (1083 aa) fasta scores: E(): 2.8e-05, 24.011% id in 379 aa 23613105 C-terminus has weak similarity to Mus musculus 2900019c14riK protein 2900019c14riK TR:Q9D6J1 (EMBL:AK013554) (393 aa) fasta scores: E(): 6e-10, 26.190% id in 210 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.675, signal anchorprobability 0.312) with cleavage site probability 0.348 between residues 24 and 25 8 probable transmembrane helices predicted by TMHMM2.0 at aa 7-25, 69-90, 123-145, 199-221, 234-256, 266-285, 315-337 and 361-380 23613106 Highest similarity to triose phosphate/ phosphate translocator; also similar to hexose phosphate/ phosphate translocator; no leader sequence. Similar to Pisum sativum triose phosphate/phosphate translocator, chloroplast precursor SW:CPTR_PEA (P21727) (402 aa) fasta scores: E(): 1.4e-35, 36.012% id in 336 aa Similar to Arabidopsis thaliana glucose 6 phosphate/phosphate translocator TR:Q9M5A9 (EMBL:AF233658) (388 aa) fasta scores: E(): 3.2e-34, 34.884% id in 301 aa 9 probable transmembrane helices predicted by TMHMM2.0 at aa 39-61, 76-95, 108-130, 135-157, 164-181, 186-203, 224-246, 268-287 and 307-341 23613107 Similar to Homo sapiens transcription factor iib TR:Q9Y6A4 (EMBL:AF093680) (193 aa) fasta scores: E(): 5.4e-24, 46.354% id in 192 aa 23613108 Similar to Plasmodium falciparum guanidine nucleotide exchange factor pfrcc1 (1327 aa) fasta scores: E(): 9.6e-190, 97.459% id in 1338 aa 23613109 Weakly similar to Arabidopsis thaliana F8n16.20 protein f8n16.20 TR:Q9ZV23 (EMBL:AC005727) (332 aa) fasta scores: E(): 2e-12, 28.763% id in 299 aa 23613110 Similar to Rattus norvegicus RNA helicase TR:Q62780 (EMBL:U25746) (1032 aa) fasta scores: E(): 2.4e-59, 38.387% id in 719 aa 23613111 Similar to Rickettsia prowazekii single-strand binding protein ssb or rp836 SW:SSB_RICPR (Q9ZCC2) (152 aa) fasta scores: E(): 1.1e-16, 38.158% id in 152 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.896, signal anchor probability 0.017) with cleavage site probability 0.471 between residues 25 and 26 23613112 Weak similarity to Plasmodium falciparum Pfc0425W protein pfc0425W TR:O77336 (EMBL:Z98547) (4550 aa) fasta scores: E(): 7.2e-23, 22.792% id in 3238 aa 23613113 Similar to Drosophila melanogaster snap protein snap or cg6625 TR:Q23983 (EMBL:AE003514) (292 aa) fasta scores: E(): 2.4e-31, 35.959% id in 292 aa 23613114 Similar to Arabidopsis thaliana chromosome condensation protein TR:Q9FJL0 (EMBL:AB015468) (1241 aa) fasta scores: E(): 1.4e-27, 27.682% id (37.354% ungapped) in 1622 aa overlap (57-1667:18-1230) 23613115 Similar to Mus musculus protein phosphatase 1, regulatory TR:AAH13524 (EMBL:BC013524) (361 aa) fasta scores: E(): 3.4e-08, 32.000% id in 250 aa 23613117 Similar to Plasmodium falciparum RNA polymerase i TR:Q26008 (EMBL:L11172) (2910 aa) fasta scores: E(): 0, 98.970% id in 2913 aa 23613119 Similar to Plasmodium falciparum asparaginyl-tRNA synthetase pfb0525W TR:O96198 (EMBL:AE001400) (610 aa) fasta scores: E(): 1.9e-55, 35.139% id in 646 aa Similar to Escherichia coli asparaginyl-trna synthetase asns or tss or b0930 SW:SYN_ECOLI (P17242) (465 aa) fasta scores: E(): 5.9e-39, 36.019% id in 422 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.657, signal anchor probability 0.325) with cleavage site probability 0.448 between residues 21 and 22 1 probable transmembrane helix predicted by TMHMM2.0 at aa 2-19 23613121 Similar to Solanum tuberosum phosphatidylinositol 4-kinase TR:Q9M4P7 (EMBL:AJ005810) (517 aa) fasta scores: E(): 8.4e-39, 52.381% id in 294 aa 23613124 Low complexity. Similar to Plasmodium falciparum Pfc0425W protein pfc0425W TR:O77336 (EMBL:Z98547) (4550 aa) fasta scores: E(): 3.4e-40, 23.626% id in 2565 aa 23613125 Residues implicated in PPIase activity and cyclosporin A-binding are present; sequence includes large N-terminal extension 23613128 Similar to Plasmodium falciparum topoisomerase i TR:Q26024 (EMBL:X83758) (839 aa) fasta scores: E(): 0, 100.000% id in 839 aa 23613131 Similar to Chlamydomonas reinhardtii flagellar WD-repeat protein Pf20 SW:PF20_CHLRE (P93107) (606 aa) fasta scores: E(): 7.5e-37, 31.622% id in 487 aa 23613132 Similar to Homo sapiens translationally controlled tumor protein TCTP or histamine releasing factor HRF SW:TCTP_HUMAN (P13693) (172 aa) fasta scores: E(): 5e-14, 34.483% id in 174 aa; also similar to sequence described as Plasmodium yoelii translationally controlled tumor protein tctP TR:Q9XYU2 (EMBL:AF124820) (154 aa) fasta scores: E(): 5.5e-49, 88.312% id in 154 aa 23613133 1 probable transmembrane helix predicted by TMHMM2.0 at aa 4-21 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.844, signal anchor probability 0.000) with cleavage site probability 0.349 between residues 17 and 18 23613134 Similar to Drosophila melanogaster fatty acid desaturase desat1 or fad or cg5887 TR:Q9U972 (EMBL:AJ245747) (383 aa) fasta scores: E(): 2.4e-32, 41.877% id in 277 aa. Long N- and C-terminal extensions 23613136 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.867, signal anchor probability 0.070) with cleavage site probability 0.277 between residues 24 and 25 1 probable transmembrane helix predicted by TMHMM2.0 at aa 330-352 23613138 Asparagine-rich Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.904, signal anchor probability 0.000) with cleavage site probability 0.568 between residues 19 and 20 1 probable transmembrane helix predicted by TMHMM2.0 at aa 180-202 23613140 Similar to Nicotiana tabacum myo-inositol 1-phosphate synthase TR:Q9LW96 (EMBL:AB009881) (510 aa) fasta scores: E(): 2.3e-54, 42.505% id in 487 aa 23613142 Similar to Drosophila melanogaster probable prefoldin subunit 6 cg7770 SW:PFD6_DROME (Q9VW56) (125 aa) fasta scores: E(): 0.0022, 30.000% id in 110 aa 23613145 Similar to Homo sapiens cdk-activating kinase assembly factor mat1 mnat1 or mat1 or cap35 SW:MAT1_HUMAN (P51948) (309 aa) fasta scores: E(): 8.1e-08, 27.451% id in 204 aa ; also similar to Mus musculus menage a trois 1 mnat1 TR:Q9D8D2 (EMBL:AK008134) (309 aa) fasta scores: E(): 1.6e-08, 28.571% id in 203 aa 23613148 Similar to Plasmodium falciparum putative gtpase rab1B TR:Q9BHN1 (EMBL:AJ409198) (200 aa) fasta scores: E(): 4e-70, 100.000% id in 200 aa 23613152 Weak similarity to Paramecium tetraurelia probable calcium/calmodulin-binding membrane protein pcm4 gk2.5 TR:Q9XY44 (EMBL:AF050520) (576 aa) fasta scores: E(): 3.2e-06, 27.160% id in 162 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.846, signal anchor probability 0.000) with cleavage site probability 0.805 between residues 19 and 20 23613155 Similar to Treponema pallidum uridine phosphorylase udp or tp1027 SW:UDP_TREPA (O83990) (258 aa) fasta scores: E(): 1.7e-15, 30.488% id in 246 aa 23613156 Similar to Caulobacter crescentus GTP-binding protein engb or cgpa or cc0766 SW:ENGB_CAUCR (Q9ZG89) (199 aa) fasta scores: E(): 9.8e-16, 35.204% id in 196 aa 23613157 1 probable transmembrane helix predicted by TMHMM2.0 at aa 10-27 Signal peptide predicted for MAL5P1.139 by SignalP 2.0 HMM (Signal peptide probabilty 0.932, signal anchor probability 0.049) with cleavage site probability 0.650 between residues 23 and 24 23613158 Similar to Melanoplus sanguinipes entomopoxvirus orf Msv235 putative cpd photolyase, similar to monodelphis domestica gb:d31902 msv235 TR:Q9YVK7 (EMBL:AF063866) (466 aa) fasta scores: E(): 2.4e-41, 41.522% id in 460 aa 23613160 Hypothetical protein, with repeat domain Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.021, signal anchor probability 0.978) with cleavage site probability 0.004 between residues 59 and 60 7 probable transmembrane helices predicted by TMHMM2.0 at aa 12-34, 44-66, 71-93, 98-120,122-144, 149-171 and 178-200 23613161 Similar to Plasmodium falciparum rab1 protein TR:Q9U466 (EMBL:AF201953) (207 aa) fasta scores: E(): 3.2e-77, 100.000% id in 207 aa 23613162 1 probable transmembrane helix predicted by TMHMM2.0 at aa 146-163 23613163 Similar to Homo sapiens hypothetical 44.3 kDa protein TR:Q9UMU0 (EMBL:AL096883) (385 aa) fasta scores: E(): 1.9e-44, 46.693% id in 257 aa 23613164 1 probable transmembrane helix predicted by TMHMM2.0 at aa 144-166 23613165 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.938, signal anchor probability 0.059) with cleavage site probability 0.480 between residues 21 and 22 3 probable transmembrane helices predicted by TMHMM2.0 at aa 2-19, 23-45 and 842-864 23613166 Similar to Schizosaccharomyces pombe aspartyl-trna synthetase spcc1223.07C TR:O74407 (EMBL:AL031579) (580 aa) fasta scores: E(): 2.5e-06, 32.450% id in 151 aa Hypothetical protein with possible t-RNA synthetase function, length = 1092 aa 23613167 Signal anchor predicted SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 0.822) with cleavage site probability 0.000 between residues 51 and 52 4 probable transmembrane helices predicted by TMHMM2.0 at aa 32-54, 67-89, 131-153 and 181-198 23613168 Similar to Arabidopsis thaliana probable ribose 5-phosphate isomerase at2g01290 or f10a8.17 SW:RPIA_ARATH (Q9ZU38) (265 aa) fasta scores: E(): 3.9e-33, 44.690% id in 226 aa 23613169 1 probable transmembrane helix predicted by TMHMM2.0 at aa 1526-1548 23613172 Similar to Saccharomyces cerevisiae chromosome iv reading frame orf Ydl209C ydl209C TR:Q12046 (EMBL:Z74257) (339 aa) fasta scores: E(): 4.5e-10, 34.061% id in 229 aa 23613173 C-terminal end of exon I similar to Treponema pallidum glpg putative protein TR:O83947 (EMBL:AE001265) (208 aa) fasta scores: E(): 2.8e-07, 31.818% id in 154 aa 5 probable transmembrane helices predicted by TMHMM2.0 at aa 267-286, 377-394, 404-423, 428-447 and 462-481 23613175 Similar to Dictyostelium discoideum phosphatidylinositol 3-kinase vps34-like pike or pik5 SW:P3K4_DICDI (P54676) (816 aa) fasta scores: E(): 4.5e-37, 49.412% id in 255 aa 23613177 Weak similarity to Plasmodium falciparum predicted amine transporter pfb0435C TR:O96181 (EMBL:AE001394) (1138 aa) fasta scores: E(): 4e-10, 21.853% id in 993 aa 14 probable transmembrane helices predicted by TMHMM2.0 at aa 252-274, 304-326, 331-350, 365-387, 476-495, 506-528, 549-571, 586-608, 640-662, 687-704, 716-738, 780-802, 852-874 and 894-916 23613179 Weak similarity to Zea mays triose phosphate/phosphate translocator, chloroplast precursor cpT SW:CPTR_MAIZE (P49133) (409 aa) fasta scores: E(): 0.065, 23.263% id in 331 aa 10 probable transmembrane helices predicted by TMHMM2.0 at aa 23-45, 55-72, 93-115, 120-142, 149-166, 176-193, 214-236, 246-265, 278-300 and 304-326 23613180 Similar to Schizosaccharomyces pombe hypothetical bola domain-containing protein spcc4b3.11C TR:Q9USK1 (EMBL:AL132870) (116 aa) fasta scores: E(): 2e-07, 40.789% id in 76 aa Hypothetical protein, length = 102 aa. Similar to Arabidopsis thaliana genomic DNA, chromosome 5, p1 clone:myh9 TR:Q9FIC3 (EMBL:AB016893) (93 aa) fasta scores: E(): 4.9e-11, 48.101% id in 79 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.807, signal anchor probability 0.000) with cleavage site probability 0.263 between residues 21 and 22 23613181 Similar to Mus musculus nif-like protein nifL TR:CAC69078 (EMBL:AJ344340) (348 aa) fasta scores: E(): 7.1e-16, 36.310% id in 168 aa Similar to Dictyostelium discoideum development protein Dg1148 dg1148 TR:Q9XYL0 (EMBL:AF111941) (306 aa) fasta scores: E(): 2.6e-16, 37.267% id in 161 aa 23613183 Similar to Plasmodium falciparum probable cation-transporting ATPase 1 SW:ATX1_PLAFA (Q04956) (1956 aa) fasta scores: E(): 0, 97.919% id in 1970 aa Large N- and C-terminal extensions 10 probable transmembrane helices predicted by TMHMM2.0 at aa 50-72, 286-308, 334-356, 361-380, 708-730, 2173-2195, 2207-2229, 2263-2282, 2302-2324 and 2334-2356 23613184 Similar to Arabidopsis thaliana putative 40s ribosomal protein s14 f24k9.19 TR:Q9CAX6 (EMBL:AC008153) (150 aa) fasta scores: E(): 2.9e-44, 81.457% id in 151 aa 23613185 Weak similarity to several tRNA pseudouridine synthases, incl. Staphylococcus aureus tRNA pseudouridine synthase a truA TR:BAB45147 (EMBL:AP003364) (267 aa) fasta scores: E(): 0.00011, 30.952% id in 126 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.925, signal anchor probability 0.071) with cleavage site probability 0.497 between residues 24 and 25 1 probable transmembrane helix predicted by TMHMM2.0 at aa 5-24 23613186 Similar to Saccharomyces cerevisiae hypothetical 32.8 kDa protein plp2 or yor281C TR:Q12017 (EMBL:X89633) (286 aa) fasta scores: E(): 1.4e-06, 28.852% id in 305 aa 23613187 Similar to Mus musculus solute carrier family 22 TR:AAH03734 (EMBL:BC003734) (406 aa) fasta scores: E(): 2.5e-18, 26.720% id in 378 aa 10 probable transmembrane helices predicted by TMHMM2.0 at aa 36-58, 68-85, 97-119, 158-180, 243-265, 280-302, 309-326, 330-349, 362-384 and 394-413 23613188 Similar to Plasmodium falciparum mb2 TR:AAK72249 (EMBL:AF378134) (925 aa) fasta scores: E(): 0, 100.000% id in 925 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.881, signal anchor probability 0.100) with cleavage site probability 0.687 between residues 27 and 28 23613189 Similar to Mus musculus ubiquitin carboxyl-terminal hydrolase 4 usp4 or unP SW:UBP4_MOUSE (P35123) (962 aa) fasta scores: E(): 4.3e-30, 30.572% id in 507 aa 23613191 Similar to Homo sapiens similar to ribosomal protein l8 TR:AAH12197 (EMBL:BC012197) (257 aa) fasta scores: E(): 1.8e-71, 67.589% id in 253 aa 23613192 Identifies the 60s ribosomal protein L12; this CDS feature was created with the help of proteomics data from M. Mann & Henk Stunnenberg study. The peptides identified in malaria proteome were KPTTIQEMIDSGEIDVPLE and VEVVPTSAALILK; This modified gene was created after deleting gene model PFE0850w 23613195 Similar to Homo sapiens splicing factor, arginine/serine-rich 1 sfrs1 or sf2p33 or asf or sf2 SW:SFR1_HUMAN (Q07955) (247 aa) fasta scores: E(): 1.3e-29, 48.117% id in 239 aa 23613196 Similar to Homo sapiens chromatin-specific transcription elongation factor fact 140 kDa subunit TR:Q9Y5B9 (EMBL:AF152961) (1047 aa) fasta scores: E(): 3.2e-51, 29.156% id in 1173 aa weak Pfam match to PF00557, peptidase M24, E()=0.018 23613197 Similar to Arabidopsis thaliana hypothetical 67.9 kDa protein TR:AAK64093 (EMBL:AY040035) (614 aa) fasta scores: E(): 4.8e-38, 30.821% id in 597 aa 2 probable transmembrane helices predicted by TMHMM2.0 at aa 10-32 and 37-59 23613198 Similar to Drosophila melanogaster f-actin capping protein beta subunit cpb or ancp-beta or cg17158 SW:CAPB_DROME (P48603) (276 aa) fasta scores: E(): 3.8e-20, 31.727% id in 249 aa 23613199 Similar to Homo sapiens eukaryotic translation initiation factor 3 subunit 9 eif3s9 SW:IF39_HUMAN (P55884) (814 aa) fasta scores: E(): 4.7e-19, 30.966% id in 704 aa, and to Arabidopsis thaliana prt1 TR:Q9M4T6 (EMBL:AF255680) (716 aa) fasta scores: E(): 2.3e-27, 30.579% id in 726 aa 23613201 Hypothetical protein with probable Zn-finger domain 23613203 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.058, signal anchor probability 0.712) with cleavage site probability 0.026 between residues 24 and 25 1 probable transmembrane helix predicted by TMHMM2.0 at aa 12-30 23613204 2 probable transmembrane helices predicted by TMHMM2.0 at aa 70-92 and 112-134 23613205 Similar to Arabidopsis thaliana proteasome subunit beta type 1 SW:PSB1_ARATH (P42742) (223 aa) fasta scores: E(): 6.2e-20, 41.525% id in 236 aa 23613206 Similar to Trypanosoma brucei cyclin 2 cyc2 TR:Q9NG22 (EMBL:AJ242519) (211 aa) fasta scores: E(): 2.5e-17, 45.736% id in 129 aa Putative cyclin2 related protein 23613207 Similar to Oryza sativa putative snrnp protein TR:AAK38497 (EMBL:AC087181) (736 aa) fasta scores: E(): 1.3e-74, 40.840% id in 857 aa 23613208 Similar to Schizosaccharomyces pombe trp-asp repeat protein spac343.04C TR:Q9UT85 (EMBL:AL109739) (507 aa) fasta scores: E(): 3.7e-26, 29.705% id in 441 aa 23613209 Similar to Arabidopsis thaliana similarity to RNA-binding protein TR:Q9LVC3 (EMBL:AB019234) (604 aa) fasta scores: E(): 1.6e-32, 41.353% id in 399 aa 23613213 Weak similarity to several histone RNA hairpin binding proteins incl Xenopus laevis oocyte-specific histone RNA stem-loop binding protein 2 slbp2 SW:SLB2_XENLA (Q9YGP6) (250 aa) fasta scores: E(): 5e-05, 26.718% id in 131 aa 23613214 Similar to Thermotoga maritima 50s ribosomal protein l14 rpln or tm1490 SW:RL14_THEMA (P38508) (122 aa) fasta scores: E(): 1e-08, 45.000% id in 100 aa 23613215 Similar to Pleurochrysis carterae vacuolar ATP synthase 16 kDa proteolipid subunit vaP SW:VATL_PLECA (Q43362) (164 aa) fasta scores: E(): 7e-34, 61.728% id in 162 aa 23613217 Similar to Arabidopsis thaliana 40s ribosomal protein s24 rps24 SW:RS24_ARATH (Q9SS17) (133 aa) fasta scores: E(): 4.3e-23, 53.906% id in 128 aa 23613219 Contains NQHQ repeats 23613222 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.131, signal anchor probability 0.846) with cleavage site probability 0.077 between residues 22 and 23 1 probable transmembrane helix predicted by TMHMM2.0 at aa 7-29 23613223 Similar to Arabidopsis thaliana 40s ribosomal protein-like f8m21_90 TR:Q9LXG1 (EMBL:AL353993) (198 aa) fasta scores: E(): 1.3e-51, 73.184% id in 179 aa, and to Rattus norvegicus 40s ribosomal protein s9 rps9 SW:RS9_RAT (P29314) (193 aa) fasta scores: E(): 3.7e-48, 72.941% id in 170 aa 23613224 Weak Similarity to Plasmodium falciparum protein phosphatase 2c TR:O43966 (EMBL:AF023665) (920 aa) fasta scores: E(): 3.6e-06, 23.485% id in 528 aa 23613226 Similar to Homo sapiens u6 snrna-associated sm-like protein Lsm2 lsm2 SW:LSM2_HUMAN (Q9Y333) (95 aa) fasta scores: E(): 1.4e-21, 65.217% id in 92 aa 23613232 Similar to Plasmodium falciparum adenosylhomocysteinase SW:SAHH_PLAF7 (P50250) (479 aa) fasta scores: E(): 2.6e-194, 99.582% id in 479 aa 23613237 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.989, signal anchor probability 0.000) with cleavage site probability 0.844 between residues 20 and 21 23613239 Similar to Homo sapiens dead-box protein 1 ddx1 SW:DDX1_HUMAN (Q92499) (740 aa) fasta scores: E(): 1.8e-25, 29.487% id in 858 aa 23613240 Similar to Rickettsia prowazekii putative ATPase n2b rp212 TR:Q9ZDV7 (EMBL:AJ235270) (357 aa) fasta scores: E(): 1.1e-18, 31.661% id in 319 aa, and to Neisseria meningitidis (serogroup A) putative nucleotide-binding protein nma1520 or nmb1306 TR:Q9JRK2 (EMBL:AL162756) (383 aa) fasta scores: E(): 1.7e-14, 27.632% id in 304 aa 23613246 3 probable transmembrane helices predicted by TMHMM2.0 at aa 264-286, 2038-2060 and 2199-2221 23613247 Similar to Synechococcus sp 50s ribosomal protein l17 rplq or rpl17 SW:RL17_SYNP6 (O24711) (116 aa) fasta scores: E(): 4.6e-14, 44.737% id in 114 aa 23613248 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.064, signal anchor probability 0.914) with cleavage site probability 0.032 between residues 35 and 36 8 probable transmembrane helices predicted by TMHMM2.0 at aa 20-42, 62-84, 88-107, 114-136, 156-175, 273-292, 302-324 and 331-353 23613249 Similar to Galdieria sulphuraria hypothetical 12.5 kDa protein TR:Q9MSA1 (EMBL:AF233069) (112 aa) fasta scores: E(): 1.8e-13, 41.593% id in 113 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998, signal anchor probability 0.000) with cleavage site probability 0.987 between residues 18 and 19 23613250 Similar to Drosophila melanogaster l l(1)10bb or lethal or cg1639 TR:O97454 (EMBL:AE003485) (144 aa) fasta scores: E(): 1.1e-32, 57.931% id in 145 aa 23613252 Similar to Plasmodium falciparum multidrug resistance protein mdr1 SW:MDR_PLAFF (P13568) (1419 aa) fasta scores: E(): 0, 100.000% id in 1419 aa 11 probable transmembrane helices predicted by TMHMM2.0 at aa 56-78, 93-115, 166-188, 192-211, 276-298, 318-340, 789-811, 831-853, 904-926, 930-949 and 1024-1046 23613256 Similar to Plasmodium falciparum protein with DNAJ domain pfb0920W TR:O96276 (EMBL:AE001425) (1014 aa) fasta scores: E(): 8.9e-23, 33.501% id in 397 aa 2 probable transmembrane helices predicted by TMHMM2.0 at aa 56-78 and 91-113 23613258 4 probable transmembrane helices predicted by TMHMM2.0 at aa 978-1000, 1021-1040, 1064-1083 and 1104-1126 23613259 11 probable transmembrane helices predicted by TMHMM2.0 at aa 239-261, 274-296, 321-343, 345-367, 382-404, 424-441, 469-491, 558-575, 585-607, 620-642 and 652-674 23613260 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.072, signal anchor probability 0.904) with cleavage site probability 0.017 between residues 21 and 22 2 probable transmembrane helices predicted by TMHMM2.0 at aa 20-42 and 52-69 23613261 Similar to Plasmodium falciparum karyopherin beta kp1 TR:AAF98803 (EMBL:AF256227) (599 aa) fasta scores: E(): 1.7e-217, 99.499% id in 599 aa 23613263 4 probable transmembrane helices predicted by TMHMM2.0 at aa 7-26, 46-65, 78-97 and 112-129 23613265 Similar to Homo sapiens developmentally regulated GTP-binding protein 1 drg1 SW:DRG1_HUMAN (Q9Y295) (367 aa) fasta scores: E(): 8.6e-100, 71.858% id in 366 aa, and to Arabidopsis thaliana GTP-binding-like protein f23k16.150 or at4g39520 TR:Q9SVA6 (EMBL:AL078620) (369 aa) fasta scores: E(): 1.3e-99, 69.945% id in 366 aa 23613267 Similar to Porphyra purpurea chloroplast 50s ribosomal protein l12 rpl12 SW:RK12_PORPU (P51339) (129 aa) fasta scores: E(): 1.1e-09, 42.222% id in 135 aa Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 0.837) with cleavage site probability 0.000 between residues 60 and 61 1 probable transmembrane helix predicted by TMHMM2.0 at aa 35-57 23613268 Similar to Arabidopsis thaliana mitochondrial import receptor subunit tom22 at5g43970 TR:Q9FNC9 (EMBL:AB006703) (99 aa) fasta scores: E(): 0.29, 34.146% id in 41 aa Putative conserved hypothetical protein 1 probable transmembrane helix predicted by TMHMM2.0 at aa 58-77 23613269 Weakly similar to Arabidopsis thaliana similar to ufd1 protein at4g15420 TR:O23395 (EMBL:Z97338) (778 aa) fasta scores: E(): 1.3e-08, 20.786% id in 611 aa Hypothetical protein 23613270 Similar to Arabidopsis thaliana hypothetical 73.0 kDa protein f22h5.13 TR:Q9FRL1 (EMBL:AC025814) (654 aa) fasta scores: E(): 9.4e-79, 54.568% id in 405 aa Similar to Homo sapiens cdna flj10900 fis, clone nt2rp5003522, weakly similar to NADPH- cytochrome p450 reductase TR:Q9NV66 (EMBL:AK001762) (732 aa) fasta scores: E(): 1.9e-78, 56.136% id in 383 aa 23613271 Putative zinc finger protein, length = 704 aa 23613272 Similar to Homo sapiens long-chain-fatty-acid--coa ligase 2 facl2 or lacs2 or lacS SW:LCFB_HUMAN (P33121) (698 aa) fasta scores: E(): 6.2e-74, 34.961% id in 635 aa Similar to Callithrix jacchus long-chain fatty acid CoA ligase mlcl1 TR:Q9GLP3 (EMBL:AF190741) (698 aa) fasta scores: E(): 4.5e-77, 36.884% id in 629 aa 23613274 Asparagine-rich 1 probable transmembrane helix predicted by TMHMM2.0 at aa 91-113 23613275 Similar to Homo sapiens testis-specific adriamycin sensitivity protein tasp or lancl2 TR:Q9NS86 (EMBL:AB035966) (450 aa) fasta scores: E(): 4e-17, 29.385% id in 439 aa, and to Homo sapiens seven transmembrane domain protein p40 or lancl1 TR:O43813 (EMBL:Y11395) (399 aa) fasta scores: E(): 4.5e-15, 28.261% id in 460 aa 7 probable transmembrane helices predicted by TMHMM2.0 at aa 47-64, 92-114, 172-191, 211-233, 325-344, 374-396 and 430-447 23613276 Contains WD40 repeats 23613277 Similar to Oryza sativa putative RNA methyltransferases TR:Q9AUK9 (EMBL:AC087851) (329 aa) fasta scores: E(): 1.9e-07, 22.118% id in 321 aa 1 probable transmembrane helix predicted by TMHMM2.0 at aa 341-363 23613278 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.995, signal anchor probability 0.000) with cleavage site probability 0.969 between residues 19 and 20 23613280 Similar to Mus musculus serine/threonine-protein kinase Nek1 nek1 SW:NEK1_MOUSE (P51954) (774 aa) fasta scores: E(): 4.1e-18, 39.459% id in 185 aa 23613281 2 probable transmembrane helices predicted by TMHMM2.0 at aa 417-439 and 459-481 23613282 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.042, signal anchor probability 0.957) with cleavage site probability 0.030 between residues 27 and 28 4 probable transmembrane helices predicted by TMHMM2.0 at aa 7-25, 317-339, 352-371 and 375-397 23613283 Asparagine-rich 23613284 Contains 5 WD40 domains 23613285 1 probable transmembrane helix predicted by TMHMM2.0 at aa 63-85 23613288 2 probable transmembrane helices predicted by TMHMM2.0 at aa 5-27 and 758-780 23613290 Similar to Arabidopsis thaliana putative transmembrane protein t4m8.28 TR:O81045 (EMBL:AC006284) (213 aa) fasta scores: E(): 1.2e-07, 23.832% id in 214 aa Putative transmembrane protein Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.998, signal anchor probability 0.001) with cleavage site probability 0.732 between residues 27 and 28 2 probable transmembrane helices predicted by TMHMM2.0 at aa 10-32 and 182-204 23613291 Similar to Schizosaccharomyces pombe minichromosome maintenance protein 3 mcm3 or spcc1682.02C SW:MCM3_SCHPO (P30666) (879 aa) fasta scores: E(): 7.2e-55, 38.202% id in 712 aa 23613292 Similar to Arabidopsis thaliana putative ubiquitin-conjugating enzyme e2 f6i1.11 TR:Q9FZ48 (EMBL:AC051629) (153 aa) fasta scores: E(): 4.8e-40, 68.707% id in 147 aa 23613293 Similar to Arabidopsis thaliana ubiquitin-specific protease 7 ubp7 TR:Q9FPT3 (EMBL:AF302661) (477 aa) fasta scores: E(): 4.3e-19, 29.716% id in 599 aa, and to Arabidopsis thaliana putative trna-guaninine transglycosylase f19c24.8 TR:AAK92752 (EMBL:AY050817) (482 aa) fasta scores: E(): 1.5e-16, 28.836% id in 593 aa 23613294 Similar to Arabidopsis thaliana methionine aminopeptidase TR:Q9FV52 (EMBL:AF250961) (369 aa) fasta scores: E(): 4.7e-39, 46.809% id in 235 aa 23613295 2 probable transmembrane helices predicted by TMHMM2.0 at aa 99-121 and 136-158 23613297 asparagine-rich 23613298 Similar to Plasmodium falciparum RNA helicase-1 TR:Q9U936 (EMBL:AJ245474) (386 aa) fasta scores: E(): 2e-126, 100.000% id in 380 aa Identitity starts at amino acid position 222 of the (EMBL:AJ245474) protein 23613299 Weakly similar to Arabidopsis thaliana unknown protein f1n21.15 TR:AAK73254 (EMBL:AY044313) (141 aa) fasta scores: E(): 2.9, 30.928% id in 97 aa 23613301 Similar to Homo sapiens eukaryotic translation initiation factor 3, subunit 6 TR:Q9BRV2 (EMBL:BC005944) (396 aa) fasta scores: E(): 2e-19, 30.714% id in 280 aa 2 probable transmembrane helices predicted by TMHMM2.0 at aa 250-269 and 291-313 23613303 Similar to Arabidopsis thaliana rec-like protein f21e1_190 TR:Q9FYD4 (EMBL:AL391716) (284 aa) fasta scores: E(): 8.2e-18, 33.460% id in 263 aa, and to Schizosaccharomyces pombe hypothetical 38.1 kDa protein c2f12.15c in chromosome ii spbc2f12.15C SW:YB3F_SCHPO (O14345) (329 aa) fasta scores: E(): 7.2e-20, 32.599% id in 227 aa, and to Homo sapiens ReC protein reC TR:Q9UIJ5 (EMBL:AB023584) (367 aa) fasta scores: E(): 2.1e-17, 28.239% id in 301 aa. Contains Pfam:zf-DHHC (zinc finger domain) 4 probable transmembrane helices predicted by TMHMM2.0 at aa 109-131, 154-176, 261-283 and 298-320 23613304 Similar to Arabidopsis thaliana alpha subunit of f-actin capping protein f22f7.3 TR:Q9MA66 (EMBL:AC009606) (308 aa) fasta scores: E(): 1.1e-05, 23.358% id in 274 aa, and to Drosophila melanogaster f-actin capping protein alpha subunit cpa or cg10540 SW:CAPA_DROME (Q9W2N0) (286 aa) fasta scores: E(): 1.2e-05, 22.464% id in 276 aa, and to Gallus gallus f-actin capping protein alpha-1 subunit SW:CAZ1_CHICK (P13127) (286 aa) fasta scores: E(): 5.8e-05, 21.818% id in 275 aa, and to Dictyostelium discoideum f-actin capping protein alpha subunit abpD SW:CAPA_DICDI (P13022) (281 aa) fasta scores: E(): 0.00012, 23.684% id in 266 aa; contains a Pfam:F-actin_cap_A domain 23613306 Similar to Arabidopsis thaliana cyclophilin-like protein at2g36130 TR:Q9SIH1 (EMBL:AC007135) (164 aa) fasta scores: E(): 6.8e-38, 66.443% id in 149 aa. Probably does not bind cyclosporin A because contains His at position 156, not Trp. 23613307 Similar to Saccharomyces cerevisiae hypothetical GTP-binding protein in ynd1-pac2 intergenic region yer006W SW:YEJ6_YEAST (P40010) (520 aa) fasta scores: E(): 4.6e-05, 24.046% id in 524 aa 23613309 Similar to Macaca fascicularis hypothetical 30.5 kDa protein TR:BAB60741 (EMBL:AB062962) (272 aa) fasta scores: E(): 3e-23, 35.943% id in 281 aa Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.109, signal anchor probability 0.650) with cleavage site probability 0.029 between residues 27 and 28 2 probable transmembrane helices predicted by TMHMM2.0 at aa 12-34 and 678-697 23613310 Similar to Guillardia theta hypothetical 16.5 kDa protein TR:Q9AW19 (EMBL:AJ010592) (139 aa) fasta scores: E(): 1.1e-11, 40.594% id in 101 aa 1 probable transmembrane helix predicted by TMHMM2.0 at aa 5-27 23613311 Similar to Staphylococcus xylosus lactose permease lacP SW:LACP_STAXY (O33814) (462 aa) fasta scores: E(): 9.5e-09, 22.247% id in 445 aa, and to Salmonella typhimurium melibiose carrier protein melB SW:MELB_SALTY (P30878) (476 aa) fasta scores: E(): 8.2e-06, 19.753% id in 486 aa, and to Bacillus subtilis probable glucitol transport protein GutA gutA SW:GUTA_BACSU (O34368) (463 aa) fasta scores: E(): 0.00019, 23.094% id in 459 aa 12 probable transmembrane helices predicted by TMHMM2.0 at aa 69-91, 106-128, 141-158, 173-195, 211-233, 248-270, 303-325, 335-357, 370-389, 394-413, 438-460 and 480-502 23613312 Weak similarity to Guillardia theta Tic22 tic22 TR:AAK39834 (EMBL:AF165818) (307 aa) fasta scores: E(): 1.5e-10, 26.471% id in 272 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.989, signal anchor probability 0.000) with cleavage site probability 0.594 between residues 17 and 18 23613313 1 probable transmembrane helix predicted by TMHMM2.0 at aa 923-945 23613314 Similar to Drosophila melanogaster Cg5941 protein cg5941 TR:Q9W445 (EMBL:AE003436) (182 aa) fasta scores: E(): 3.6e-32, 50.292% id in 171 aa, and to Homo sapiens multiple copies in a t-cell malignancies mct-1 TR:Q9ULC4 (EMBL:AB034206) (181 aa) fasta scores: E(): 1.6e-31, 50.000% id in 170 aa 23613317 4 probable transmembrane helices predicted by TMHMM2.0 at aa 59-81, 94-116, 146-163 and 178-200 23613320 Weak similarity to Arabidopsis thaliana syntaxin 52 syp52 TR:AAK40224 (EMBL:AF355756) (233 aa) fasta scores: E(): 0.0059, 26.829% id in 205 aa 1 probable transmembrane helix predicted by TMHMM2.0 at aa 205-224 23613321 Similar to Mesembryanthemum crystallinum phosphoenolpyruvate/phosphate translocator precursor ppT TR:Q9MSB5 (EMBL:AF223359) (417 aa) fasta scores: E(): 6.3e-19, 30.564% id in 337 aa 7 probable transmembrane helices predicted by TMHMM2.0 at aa 224-246, 296-318, 338-357, 405-424, 444-466, 473-495 and 500-519 23613324 Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.743, signal anchor probability 0.252) with cleavage site probability 0.464 between residues 24 and 25 10 probable transmembrane helices predicted by TMHMM2.0 at aa 5-27, 203-225, 284-306, 327-349, 408-430, 466-488, 521-543, 590-609, 619-641 and 662-684 23613325 Similar to Drosophila melanogaster Cg12259 protein cg12259 TR:Q9VAY7 (EMBL:AE003763) (359 aa) fasta scores: E(): 1.4e-23, 41.778% id in 225 aa 23613329 2 probable transmembrane helices predicted by TMHMM2.0 at aa 219-238 and 682-704 23613334 Similar to Plasmodium falciparum hypothetical 9.6 kDa protein TR:Q9NFH0 (EMBL:AJ290927) (98 aa) fasta scores: E(): 7.2e-19, 100.000% id in 98 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.989, signal anchor probability 0.000) with cleavage site probability 0.950 between residues 24 and 25 1 probable transmembrane helix predicted by TMHMM2.0 at aa 112-134 23613335 Signal anchor predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.200, signal anchor probability 0.751) with cleavage site probability 0.099 between residues 26 and 27 1 probable transmembrane helix predicted by TMHMM2.0 at aa 2-24 23613337 Similar to Plasmodium falciparum protein with DNAJ domain pfb0920W TR:O96276 (EMBL:AE001425) (1014 aa) fasta scores: E(): 2.2e-10, 23.800% id in 479 aa 1 probable transmembrane helix predicted by TMHMM2.0 at aa 47-66 36329003373 VAR-related fragment 36329003374 VAR-related fragment 23613340 Similar to Plasmodium falciparum rifin pfb1005W TR:O96288 (EMBL:AE001432) (316 aa) fasta scores: E(): 3.2e-44, 47.095% id in 327 aa Signal peptide predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.948, signal anchor probability 0.000) with cleavage site probability 0.280 between residues 23 and 24 2 probable transmembrane helices predicted by TMHMM2.0 at aa 126-148 and 276-298 36329003376 Rifin-fragment Similar to Plasmodium falciparum Pfc1115W protein pfc1115W TR:O97311 (EMBL:AL034559) (371 aa) fasta scores: E(): 3.1e-09, 60.938% id in 64 aa 23613341 Similar to Plasmodium falciparum fcr3 csa ligand var TR:Q9U5M2 (EMBL:AJ133811) (3542 aa) fasta scores: E(): 0, 64.378% id in 3248 aa This seems to be peculiar var-related gene as there is no 2-exon gene structure and it seems as if it is a truncated form of a var gene with single exon made up of 2 fused exons 23612085 Similar to Plasmodium falciparum rifin pfc1115w, mal3p7.54 SWALL:O97311 (EMBL:AL034559) (371 aa) fasta scores: E(): 7.9e-53, 57.18% id in 383 aa 36329003380 Putative RIF pseudogene, stop codon in exon 2 23612087 Similar to Plasmodium falciparum rifin pfc1115w, mal3p7.54 SWALL:O97311 (EMBL:AL034559) (371 aa) fasta scores: E(): 2.5e-69, 56.13% id in 383 aa 23612089 Similar to Plasmodium falciparum rifin pfc1115w, mal3p7.54 SWALL:O97311 (EMBL:AL034559) (371 aa) fasta scores: E(): 8.5e-52, 47.42% id in 388 aa 23612090 Similar to Plasmodium falciparum rifin pfb1050W SWALL:O96295 (EMBL:AE001434) (327 aa) fasta scores: E(): 5.6e-45, 45.48% id in 332 aa 23612091 Similar to Plasmodium falciparum rifin pfc1115w, mal3p7.54 SWALL:O97311 (EMBL:AL034559) (371 aa) fasta scores: E(): 1.9e-57, 50.66% id in 375 aa 23612092 Similar to Plasmodium falciparum stevor pfc1105w, mal3p7.52 SWALL:Q9U5M0 (EMBL:AL034559) (301 aa) fasta scores: E(): 5.9e-80, 74.66% id in 296 aa 36329003389 Putative RIF pseudogene. Stop codon in exon 2. Similar to Plasmodium falciparum rifin pfc1095w, mal3p7.50 SWALL:O97309 (EMBL:AL034559) (349 aa) fasta scores: E(): 2e-41, 43.4% id in 364 aa 23612094 Similar to Plasmodium falciparum conserved hypothetical membrane protein pfc1090w, mal3p7.49 SWALL:O97308 (EMBL:AL034559) (309 aa) fasta scores: E(): 4.2e-77, 93.85% id in 309 aa, and to Plasmodium falciparum predicted integral membrane protein pfb0995W SWALL:Q9TY93 (EMBL:AE001431) (257 aa) fasta scores: E(): 7.5e-57, 92.21% id in 257 aa 23612095 match to PfaDd2|1437c3|1999.12.28|EST|UFla 1..413 blast score 811 percent identity 100 none Similar to Plasmodium falciparum hypothetical 15.6 kDa protein pfb0965C SWALL:O96285 (EMBL:AE001430) (136 aa) fasta scores: E(): 1.9e-33, 77.2% id in 136 aa 23612096 Similar to Plasmodium falciparum predicted integral membrane protein pfb0985C SWALL:O96287 (EMBL:AE001431) (186 aa) fasta scores: E(): 5.2e-52, 88.42% id in 190 aa 23612097 Similar to Plasmodium falciparum pfc1075w protein pfc1075w or pfb0980W SWALL:O97462 (EMBL:AL034559) (282 aa) fasta scores: E(): 2.9e-97, 99.64% id in 282 aa 36329003394 VAR pseudogene fragment 36329003395 VAR pseudogene fragment 23612099 Similar to Methanococcus jannaschii hypothetical protein Mj0798 mj0798 SWALL:Y798_METJA (SWALL:Q58208) (334 aa) fasta scores: E(): 4.2e-05, 28.39% id in 236 aa 23612103 Similar to Schizosaccharomyces pombe putative helicase c6f12.16c spac6f12.16C SWALL:YDVG_SCHPO (SWALL:O14232) (1117 aa) fasta scores: E(): 1.1e-102, 35.67% id in 1295 aa; putative ATP dependent RNA helicase 23612104 Pfam match to MYND finger(2.2e-07) domain Similar to Homo sapiens Hskm-B hskm-B SWALL:Q9NRG4 (EMBL:AF226053) (433 aa) fasta scores: E(): 0.00041, 51.11% id in 45 aa 23612105 Similar to Methanococcus jannaschii hypothetical protein Mj0711 mj0711 SWALL:Y711_METJA (SWALL:Q58121) (322 aa) fasta scores: E(): 0.04, 23.93% id in 259 aa 23612106 Similar to Buchnera aphidicola elongation factor g fusa or bu527 SWALL:EFG_BUCAI (SWALL:P57593) (702 aa) fasta scores: E(): 1.1e-40, 35.8% id in 849 aa 23612107 Similar to Candida albicans type ii proteins geranylgeranyltransferase beta subunit bet2 SWALL:BET2_CANAL (SWALL:O93830) (341 aa) fasta scores: E(): 1.1e-35, 36.61% id in 366 aa 23612108 Pfam match to SAC3/GANP family(2.8e-08):an evolutionary consevred eukaryotic protein family involved in regulator of mitosis as a novel mediator nuclear protein export; BLASTP and FASTA did not produce any significant hit to SAC3/GANp family of protein 23612110 Very weak HMMSmart hit (1.97e-01) to JmjC domain, a domain family that is part of the cupin mettaloenzyme superfamily Similar to Neurospora crassa conserved hypothetical protein b15i20.20 SWALL:Q9P3K9 (EMBL:AL389900) blast scores: E(): 8e-09, score: 64 36% id 23612114 Similar to Saccharomyces cerevisiae bcs1 protein bcs1 or ydr375c or d9481.17 SWALL:BCS1_YEAST (SWALL:P32839) (456 aa) fasta scores: E(): 8.1e-40, 40.61% id in 421 aa 23612115 Similar to Plasmodium falciparum dihydroorotate dehydrogenase homolog, mitochondrial precursor SWALL:PYRD_PLAFA (SWALL:Q08210) (569 aa) fasta scores: E(): 0, 100% id in 569 aa 23612116 Putative Zn-finger motif at the C-terminus 23612117 Similar to Schizosaccharomyces pombe putative ion transporter c1795.02c spcc1795.02c or spcc895.01 SWALL:O59768 (EMBL:AL022598) (412 aa) fasta scores: E(): 4.6e-49, 41.98% id in 362 aa, and to Arabidopsis thaliana high affinity calcium antiporter cax1 SWALL:Q39253 (EMBL:U57411) (427 aa) fasta scores: E(): 3.6e-24, 38.69% id in 398 aa 23612118 Weak Pfam and HMMSmart hit to ARID (A/T-rich interaction domain)/BRIGHT DNA binding domain 23612119 Similar to Saccharomyces cerevisiae phenylalanyl-trna synthetase, mitochondrial precursor msf1 or ypr047w or yp9499.05 SWALL:SYFM_YEAST (SWALL:P08425) (474 aa) fasta scores: E(): 1.1e-25, 30.68% id in 440 aa 23612121 Similar to Plasmodium falciparum hypothetical 118.9 kDa protein pfb0765W SWALL:O96246 (EMBL:AE001417) (980 aa) fasta scores: E(): 1.9e-05, 28.28% id in 350 aa 23612123 match to Pfa3D7|4200|2000.12.28|EST|UTokyo 1..446 blast score 884 percent identity 100 none 23612127 Weak Pfam and HMMSmart hit to GYF (conserved Gly- Tyr-Phe residues) domain 23612128 Similar to Arabidopsis thaliana similarity to hepa-related protein harp SWALL:Q9FF11 (EMBL:AB005249) blast scores: E(): 4e-25, score: 295 27% id, and to Mus musculus hepa-related protein harp SWALL:Q9EQK8 (EMBL:AF209773) blast scores: E(): 2e- 20, score: 255 32% id 23612129 Pfam match (0.0005) to Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;codon 59-185 Also known as lactoylglutathione lyase / methylglyoxylase / aldoketomutase / ketone aldehyde mutase Similar to Brassica oleracea putative lactoylglutathione lyase SWALL:LGUL_BRAOL (SWALL:Q39366) blast scores: E(): 1e-04, score: 49 24% id, and to Vibrio cholerae probable lactoylglutathione lyase gloa or vc1010 SWALL:LGUL_VIBCH (SWALL:Q9KT93) blast scores: E(): 0.32, score: 37 29% id, and to Oryza sativa glyoxalase i glx-I SWALL:Q948T6 (EMBL:AB050986) blast scores: E(): 7e-05, score: 49 24% id 23612132 Similar to Xenopus laevis ribosomal protein L24 l24 SWALL:Q9W6Z1 (EMBL:Y17113) (276 aa) fasta scores: E(): 5.3e-08, 31.08% id in 148 aa, and to Synechococcus sp. 50s ribosomal protein l24 rplx or rpl24 SWALL:RL24_SYNP6 (SWALL:O24700) (113 aa) fasta scores: E(): 3.3e- 07, 41% id in 100 aa 23612134 Several weak FASTA hits to acylphosphatases 23612135 Similar to Homo sapiens serine/threonine kinase 15 SWALL:Q9BQD6 (EMBL:BC006423) blast scores: E(): 8e- 42, score: 431 32% id, and to Rattus norvegicus aim-1 SWALL:O55099 (EMBL:D89731) (343 aa) fasta scores: E(): 4.2e-23, 33.55% id in 298 aa 23612136 Similar to SWALL:D112_MOUSE (SWALL:) (148 aa) fasta scores: E(): 0.0035, 24.46% id in 139 aa 23612137 Similar to Mus musculus cdk3-binding protein ik3-1 cableS SWALL:Q9EPR8 (EMBL:AF328140) (568 aa) fasta scores: E(): 2.8e-10, 34.97% id in 183 aa 23612138 Similar to Aquifex aeolicus nucleoside diphosphate kinase ndk or aq_1590 SWALL:NDK_AQUAE (SWALL:O67528) (142 aa) fasta scores: E(): 9.1e-05, 29.71% id in 138 aa 23612140 Similar to Mus musculus rad50 rad50 or rad50 SWALL:P70388 (EMBL:U66887) blast scores: E(): 2e-49, score: 504 41% id, and to Saccharomyces cerevisiae DNA repair protein rad50 rad50 or ynl250w or n0872 SWALL:RA50_YEAST (SWALL:P12753) blast scores: E(): 1e-45, score: 471 25% id 23612143 Similar to Arabidopsis thaliana RNA-binding protein, putative f22g10.7 SWALL:Q9C8M0 (EMBL:AC024260) blast scores: E(): 4e-08, score: 61 22% id 23612144 Similar to Schizosaccharomyces pombe probable ubiquitin-conjugating enzyme e2-17 kDa ubc16 or spbc1198.09 SWALL:UBCG_SCHPO (SWALL:Q9P6I1) blast scores: E(): 7e- 33, score: 351 48% id, and to Pichia angusta ubiquitin-conjugating enzyme e2-21 kDa pex4 SWALL:UBCX_PICAN (SWALL:O60015) blast scores: E(): 2e-29, score: 322 38% id 23612147 Similar to Mus musculus neural polypyrimidine tract binding protein ptbp2 SWALL:Q91Z31 (EMBL:BC010255) blast scores: E(): 7e-36, score: 383 25% id 23612148 match to Pfa3D7|2679|2000.12.28|EST|UTokyo 1..151 blast score 299 percent identity 100 match to Pfa3D7|2679|2000.12.28|EST|UTokyo 259..500 blast score 464 percent identity 100 Asparagine-rich protein 23612149 With putative 7 WD40 repeat domains Similar to Bos taurus coatomer alpha subunit copA SWALL:COPA_BOVIN (SWALL:Q27954) (1224 aa) fasta scores: E(): 1.5e-43, 30.17% id in 1551 aa 23612151 Codons 140-146 are possible active site residues. Significant hit to tigrfam:TIGR00365;TIGR00365: glutaredoxin-related protein;1.9e-43;codon 116-215 Similar to Homo sapiens pkcq-interacting protein picot picot or ba500g10.1 SWALL:Q9P1B0 (EMBL:AF118652) blast scores: E(): 4e-21, score: 252 50% id, and to Anabaena sp. hypothetical protein Alr0799 alr0799 SWALL:BAB72756 (EMBL:AP003583) (107 aa) fasta scores: E(): 7.8e-16, 54.73% id in 95 aa, and to Homo sapiens similar to thioredoxin-like 2 SWALL:Q96CE0 (EMBL:BC014372) (189 aa) fasta scores: E(): 6e-14, 44.54% id in 110 aa 23612152 Similar to Homo sapiens translation initiation factor if-2 if2 or kiaa0741 SWALL:IF2P_HUMAN (SWALL:O60841) (1220 aa) fasta scores: E(): 4.1e-76, 41.65% id in 1037 aa 23612153 With putative MYND type Zn-finger Pfam domain in the C-terminus; The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein in human (PMID:9584201) 23612154 Similar to Arabidopsis thaliana hypothetical 55.0 kDa protein f4d11.200 or at4g32600 SWALL:O65539 (EMBL:AL022537) blast scores: E(): 8e-08, score: 60 37% id, and to Arabidopsis thaliana pspzf zinc finger protein-like at5g10650 SWALL:Q9FT67 (EMBL:AL392144) blast scores: E(): 7e-07, score: 57 38% id 23612155 Similar to Saccharomyces cerevisiae uroporphyrinogen decarboxylase hem12 or hem6 or pop3 or yd9609.03 SWALL:DCUP_YEAST (SWALL:P32347) (362 aa) fasta scores: E(): 1.4e-31, 32.59% id in 362 aa, and to Campylobacter jejuni uroporphyrinogen decarboxylase heme or cj1243 SWALL:Q9PN54 (EMBL:AL139077) (340 aa) fasta scores: E(): 4.7e-35, 37.53% id in 341 aa 23612156 Significant Pfam hit (4.4e-29) to EXS family Similar to Arabidopsis thaliana hypothetical 90.6 kDa protein f10d13_13 SWALL:Q9C789 (EMBL:AC073178) blast scores: E(): 2e-23, score: 277 30% id, and to Drosophila melanogaster ld30826p cg7536 SWALL:Q960X7 (EMBL:AY051791) blast scores: E(): 1e-21, score: 261 32% id 23612157 Similar to Schizosaccharomyces pombe para-hydroxybenzoate--polyprenyltransferase, mitochondrial precursor coq2 or ppt1 or spac56f8.04C SWALL:COQ2_SCHPO (SWALL:Q10252) (358 aa) fasta scores: E(): 4.8e-18, 30.67% id in 326 aa, and to Rickettsia conorii 4-hydroxybenzoate octaprenyltransferase ubia or rc1049 SWALL:Q92GS3 (EMBL:AE008656) (282 aa) fasta scores: E(): 1.9e-20, 32.15% id in 283 aa 23612158 Asparagine-rich Similar to Mus musculus 2810453l12riK protein 2810453l12riK SWALL:Q9CYT4 (EMBL:AK013338) blast scores: E(): 2e-07, score: 60 39% id 23612159 Asparagine-rich 23612162 Contains putative WD40-like repeats Similar to Schizosaccharomyces pombe hypothetical 35.0 kDa protein spcc18.15 SWALL:O74865 (EMBL:AL031907) (310 aa) fasta scores: E(): 4.2e-11, 25% id in 240 aa, and to Mus musculus 2810443j12riK protein 2810443j12riK SWALL:Q9CYU6 (EMBL:AK013297) (477 aa) fasta scores: E(): 1.6e-10, 26.19% id in 313 aa, and to Arabidopsis thaliana genomic DNA, chromosome 5, p1 clone:mjh22 SWALL:Q9FM51 (EMBL:AB009051) blast scores: E(): 2e-21, score: 257 31% id 23612167 Similar to Oryza sativa proteasome subunit alpha type 2 pab1 SWALL:PSA2_ORYSA (SWALL:Q9LSU2) (235 aa) fasta scores: E(): 4.1e-50, 57.44% id in 235 aa 23612169 Similar to Oryctolagus cuniculus t-complex protein 1, zeta subunit cct6 SWALL:TCPZ_RABIT (SWALL:O77622) blast scores: E(): e-138, score: 1253 46% id, and to Mus musculus t-complex protein 1, zeta subunit cct6a or cct6 or cctz or cctz1 SWALL:TCPZ_MOUSE (SWALL:P80317) blast scores: E(): e-137, score: 1249 46% id 23612170 Similar to Plasmodium falciparum ornithine aminotransferase oaT SWALL:OAT_PLAFD (SWALL:Q07805) (414 aa) fasta scores: E(): 1.7e-167, 100% id in 414 aa 23612172 Asparagine-rich 23612173 Weak hit (2.9e-04) to Pfam Zinc transporter family between codon 185-328; 8 probable transmembrane helices predicted by TMHMM2.0 at aa 4-26, 46-68, 92-114, 186-208, 218-240, 247-269, 279-301 and 314-336 23612174 Weak blastp hits to large number of prokaryotic citrate synthases. Also weak Pfam hit, e()=0.37, to PFAM:PF00285 Citrate synthase. Similar to Legionella pneumophila PrpC prpC SWALL:Q9XBT3 (EMBL:AF157018) blast scores: E(): 3e-07, score: 58 30% id, and to Escherichia coli O157:H7 putative citrate synthase, propionate metabolism? prpc or z0428 or ecs0386 SWALL:BAB33809 (EMBL:AE005212) blast scores: E(): 9e-07, score: 56 26% id 23612176 Similar to Clostridium perfringens cardiolipin synthetase cls or clsd or cpe1430 SWALL:CLS_CLOPE (SWALL:Q9ZNC6) blast scores: E(): 2e-13, score: 79 24% id, and to Lactococcus lactis cardiolipin synthase clsa or ll0960 SWALL:Q9CGY2 (EMBL:AE006330) blast scores: E(): 2e-13, score: 79 36% id 23612177 3' trucated at end of contig 23612178 5' truncated at end of contig 23612181 Contains putative DHHC type zinc finger domain between codons 89-153; 4 probable transmembrane helices predicted by TMHMM2.0 at aa 20-42, 52-71, 145-167 and 187- 209 Similar to Mus musculus 5033406l14riK protein 5033406l14riK SWALL:Q9D3Q8 (EMBL:AK017158) blast scores: E(): 3e-30, score: 332 38% id, and to Arabidopsis thaliana at3g09320/f3l24_19 SWALL:Q93VV0 (EMBL:AY057741) blast scores: E(): 4e-28, score: 313 31% id, and to Saccharomyces cerevisiae hypothetical 39.2 kDa protein in egt2-kre1 intergenic region ynl326c or n0325 SWALL:YN66_YEAST (SWALL:P42836) blast scores: E(): 6e-25, score: 286 32% id 23612182 Weak similarity to a transcription factor IIIc from Homo sapiens SWALL:Q9Y5Q9 Similar to Homo sapiens transcription factor iiic102 SWALL:Q9Y5Q9 (EMBL:AF133123) blast scores: E(): 2e-07, score: 61 26% id 23612183 Weak hits to ribosomal protein L19 protein from several organsims; also weak pfam hit to ribosomal protein L19 Similar to Helicobacter pylori 50s ribosomal protein l19 rpls or hp1147 SWALL:RL19_HELPY (SWALL:P56044) (118 aa) fasta scores: E(): 0.0056, 27.17% id in 92 aa, and to Bacillus stearothermophilus 50s ribosomal protein l19 rplS SWALL:RL19_BACST (SWALL:P30529) (116 aa) fasta scores: E(): 0.022, 26.37% id in 91 aa 23612184 Similar to Homo sapiens step ii splicing factor slu7 SWALL:Q96FM9 (EMBL:BC010634) (586 aa) fasta scores: E(): 3.4e-35, 38.27% id in 452 aa 23612185 Contains putative RNA-recognition domain Similar to Mus musculus 2600011c06riK protein 2600011c06riK SWALL:Q9CT49 (EMBL:AK011184) blast scores: E(): 8e-12, score: 74 30% id, and to Homo sapiens Wugsc:h_dj0687k01.2 protein wugsc:h_dj0687k01.2 SWALL:Q9UIE9 (EMBL:AC004858) blast scores: E(): 8e-12, score: 74 30% id, and to Drosophila melanogaster bcdna:ld23634 protein bcdna:ld23634 or cg4119 SWALL:Q9V3Y5 (EMBL:AE003435) blast scores: E(): 5e-10, score: 68 29% id 23612186 Similar to Caenorhabditis elegans t10c6.13 protein t10c6.13 or his-9 or f08g2.3 or 2o113 or f07b7.5 SWALL:Q9TW44 (EMBL:Z93388) (136 aa) fasta scores: E(): 1.3e-19, 73.52% id in 136 aa, and to Tortula ruralis histone h3 rnp49 SWALL:Q9XEG6 (EMBL:AF093108) (117 aa) fasta scores: E(): 1.3e-19, 67.82% id in 115 aa, and to Xenopus laevis histone gene cluster xlh1 with genes h3, h4, h2b, h2a and h1b SWALL:Q92134 (EMBL:X03017) (76 aa) fasta scores: E(): 1.5e-19, 95.45% id in 66 aa 23612188 Similar to Plasmodium falciparum Cdpk2 protein cdpk2 SWALL:O15865 (EMBL:X99763) (513 aa) fasta scores: E(): 3e-175, 99.6% id in 501 aa 23612190 Similar to Saccharomyces cerevisiae transketolase 1 tkl1 or ypr074c or yp9499.29C SWALL:TKT1_YEAST (SWALL:P23254) (679 aa) fasta scores: E(): 4e-121, 48.89% id in 677 aa 23612191 Similar to Homo sapiens dsif p160 SWALL:O43279 (EMBL:AB000516) blast scores: E(): 4e-28, score: 319 25% id, and to Saccharomyces cerevisiae transcription initiation protein spt5 spt5 or yml010w or ym9571.08 SWALL:SPT5_YEAST (SWALL:P27692) blast scores: E(): 7e-18, score: 95 24% id 23612192 Similar to Homo sapiens hypothetical protein SWALL:Q96HV5 (EMBL:BC008043) blast scores: E(): 8e-09, score: 62 26% id, and to Caenorhabditis elegans D2013.10 protein d2013.10 SWALL:O62126 (EMBL:Z47808) blast scores: E(): 2e-07, score: 57 33% id, and to Drosophila melanogaster ld12309p cg8408 SWALL:Q95RT5 (EMBL:AY061150) blast scores: E(): 4e-07, score: 57 26% id 23612196 Contains putative SWIB domain; Pfam hit (4.6e-04) and HMMSmart hit (1.54e-03) to SWIB domain between amino acid residues 262 and 334 23612199 Similar to Plasmodium falciparum asparagine-rich protein SWALL:Q95Z20 (EMBL:Y09082) (541 aa) fasta scores: E(): 6.2e-148, 98.89% id in 541 aa 23612202 Similar to Homo sapiens eukaryotic translation initiation factor 3 subunit 6 interacting protein eif3s6iP SWALL:Q9Y262 (EMBL:AF077207) blast scores: E(): 8e-60, score: 587 29% id, and to Mus musculus 67 kDa polymerase-associated factor Paf67 paf67 SWALL:Q91YE4 (EMBL:AJ310346) blast scores: E(): 9e-59, score: 578 29% id, and to Caenorhabditis elegans hypothetical 62.5 kDa protein c17g10.9 SWALL:Q95QW0 (EMBL:U28739) (537 aa) fasta scores: E(): 4.2e-27, 26.12% id in 532 aa, and to Homo sapiens eukaryotic translation initiation factor 3 subunit 6 interacting protein eif3s6iP SWALL:Q9Y262 (EMBL:AF077207) (564 aa) fasta scores: E(): 1.6e-25, 30.01% id in 513 aa, and to Oryza sativa ests au082761 p0452f10.25 SWALL:BAB78688 (EMBL:AP001859) (565 aa) fasta scores: E(): 1.6e-25, 28.01% id in 514 aa 23612203 Contains Leucine-rich repeats 23612206 Similar to Arabidopsis thaliana At2g44270 protein at2g44270 SWALL:O64862 (EMBL:AC004521) (358 aa) fasta scores: E(): 5.1e-34, 34.5% id in 455 aa, and to Dictyostelium discoideum Veg136 protein veg136 SWALL:V136_DICDI (SWALL:Q94480) (357 aa) fasta scores: E(): 2.4e-33, 33.33% id in 468 aa, and to Schizosaccharomyces pombe hypothetical 37.9 kDa protein c2g5.03 in chromosome ii spbc2g5.03 SWALL:O94282 (EMBL:AL033385) (335 aa) fasta scores: E(): 8.3e-32, 32.77% id in 476 aa; hypothetical protein, conserved 23612207 1 probable transmembrane helix predicted for PFF.299 by TMHMM2.0 at aa 324-346 Similar to Plasmodium falciparum membrane protein pf12 precursor SWALL:PF12_PLAFA (SWALL:P19259) (347 aa) fasta scores: E(): 3.8e- 135, 99.42% id in 347 aa 23612210 Similar to Caenorhabditis elegans probable nucleolar GTP-binding protein 1 t07a9.9 SWALL:NOG1_CAEEL (SWALL:O44411) (681 aa) fasta scores: E(): 2e-68, 39.46% id in 707 aa, and to Homo sapiens putative g-binding protein SWALL:O60747 (EMBL:AF065393) (562 aa) fasta scores: E(): 2e-58, 40.28% id in 571 aa, and to Arabidopsis thaliana probable nucleolar GTP-binding protein 1 at1g50920 or f8a12.14 SWALL:NOG1_ARATH (SWALL:Q9C6I8) (671 aa) fasta scores: E(): 6.5e-56, 40.02% id in 722 aa, and to Trypanosoma brucei brucei nucleolar GTP-binding protein 1 nog1 SWALL:NOG1_TRYBB (SWALL:Q9U6A9) (655 aa) fasta scores: E(): 1.8e-55, 37.09% id in 709 aa 23612211 1 internal exon could be missing in this model 23612214 7 probable transmembrane helices predicted by TMHMM2.0 at aa 115-146, 156-178, 255-272, 282-304, 510-532, 536-558 and 565-587 Similar to Homo sapiens possible integral membrane jfp11 SWALL:Q96S06 (EMBL:AE006465) (567 aa) fasta scores: E(): 2.6e-10, 26.64% id in 259 aa 23612215 Similarity ribosomal protein L18 from several organisms Similar to Buchnera aphidicola 50s ribosomal protein l18 rplr or bu508 SWALL:RL18_BUCAI (SWALL:P57575) (122 aa) fasta scores: E(): 0.001, 40.77% id in 103 aa, and to Thermotoga maritima 50s ribosomal protein l18 rplr or tm1484 SWALL:RL18_THEMA (SWALL:Q9ZAE3) (122 aa) fasta scores: E(): 0.0013, 39.85% id in 133 aa, and to Vibrio proteolyticus 50s ribosomal protein l18 rplR SWALL:RL18_VIBPR (SWALL:P52863) (117 aa) fasta scores: E(): 0.0038, 30.95% id in 126 aa 23612216 Pfam hit (3.9e-07) to Adaptin N terminal region between codons 36-843; Annotation is based on BLASTP results and Pfam hit Similar to Homo sapiens adapter-related protein complex 3 beta 2 subunit ap3b2 SWALL:A3B2_HUMAN (SWALL:Q13367) blast scores: E(): 1e-18, score: 97 31% id, and to Mus musculus similar to adaptor-related protein complex ap-3, beta 1 subunit ap3b1 SWALL:Q91YR4 (EMBL:BC015068) blast scores: E(): 2e-17, score: 94 29% id, and to Schizosaccharomyces pombe beta adaptin-like protein spbc947.02 SWALL:O43079 (EMBL:AL021837) blast scores: E(): 5e-14, score: 82 29% id 23612218 Pfam hit (2.5e-12) to Sec1 domain: the Sec1 family of proteins is thought to function in both non-neuronal and neuronal secretion. Similar to Homo sapiens syntaxin binding protein 1 stxbp1 or unc18A SWALL:AAH15749 (EMBL:D63851) (594 aa) fasta scores: E(): 2.1e-12, 24.32% id in 707 aa, and to Mus musculus syntaxin binding protein 1 stxbp1 SWALL:AAL37391 (EMBL:AF326545) (594 aa) fasta scores: E(): 2.1e-12, 24.32% id in 707 aa 23612219 This gene model could be divided into 2 separate hypothetical genes: the first exon makes the first gene and the last 2 exons make the second hypothetical gene 23612220 Strong Pfam hit (5.3e-21) to Myosin head (motor domain) between codons; HMMSmart hit (2.8e-27) Myosin. Large ATPases between codons 71-897 Similar to Plasmodium falciparum myosin a SWALL:Q9UAR6 (EMBL:AF105117) blast scores: E(): 2e-51, score: 520 21% id, and to Dictyostelium discoideum MyoM protein myoM SWALL:Q9TW28 (EMBL:AB017910) blast scores: E(): 5e-39, score: 414 21% id, and to Notothenia coriiceps myosin heavy chain myohc-a4 cdnA SWALL:Q98TQ4 (EMBL:AJ243769) blast scores: E(): 3e-36, score: 390 20% id, and to Homo sapiens myosin heavy chain, fast skeletal muscle, embryonic myh3 SWALL:MYH3_HUMAN (SWALL:P11055) blast scores: E(): 2e-35, score: 383 23% id 23612221 The existence of the second exon is uncertain Similar to Saccharomyces cerevisiae thiamine biosynthetic bifunctional enzyme [includes: thiamine- phosphate pyrophosphorylase thi6 or ypl214C SWALL:THI6_YEAST (SWALL:P41835) (540 aa) fasta scores: E(): 1.9e-13, 28.09% id in 299 aa, and to Aquifex aeolicus probable thiamine-phosphate pyrophosphorylase thie or aq_558 SWALL:THIE_AQUAE (SWALL:O66833) (215 aa) fasta scores: E(): 2.6e-12, 33.53% id in 164 aa, and to Campylobacter jejuni thiamin-phosphate pyrophosphorylase thie or cj1081C SWALL:Q9PNL3 (EMBL:AL139077) blast scores: E(): 3e-11, score: 71 33% id 23612222 It is possible that the 2 exons of this gene form 2 separate hypothetical proteins; The similarity to Arabidopsis thaliana narf-like protein is not strong enough to call this as NARF-like protein Similar to Arabidopsis thaliana narf-like protein SWALL:Q94CL6 (EMBL:AJ320258) blast scores: E(): 4e-11, score: 73 27% id 23612225 Similarities to several 60S ribosomal protein L19 and strong Pfam hit (4.5e-81) to ribosomal protein L19e between codons 15-162 Similar to Drosophila melanogaster cg2746-pa rpl19 or cg2746 SWALL:Q9W0X4 (EMBL:AE003465) (203 aa) fasta scores: E(): 1.1e-39, 61.29% id in 186 aa, and to Arabidopsis thaliana 60S ribosomal protein l19-3 rpl19c or at4g02230 or t2h3.3 SWALL:R19C_ARATH (SWALL:P49693) (208 aa) fasta scores: E(): 9.3e-39, 56.9% id in 181 aa, and to Homo sapiens 60S ribosomal protein l19 rpl19 SWALL:RL19_HUMAN (SWALL:P14118) (196 aa) fasta scores: E(): 1.4e-38, 60.77% id in 181 aa 23612226 Existence of the second exon is questionable; other possibility exits for the second exon structure 23612227 The existence of the third exon is not certain 23612228 Strong Pfam hit (2.8e-63) to HhH-GPD superfamily base excision DNA repair protein between codons 226-381 Similar to Schizosaccharomyces pombe endonuclease iii homolog nth1 or spac30d11.07 SWALL:END3_SCHPO (SWALL:Q09907) (355 aa) fasta scores: E(): 1e-26, 47.39% id in 211 aa, and to Caenorhabditis elegans probable endonuclease iii homolog r10e4.5 SWALL:END3_CAEEL (SWALL:P54137) (259 aa) fasta scores: E(): 8.4e-26, 43.31% id in 217 aa, and to Mus musculus endonuclease iii homologue nth1 or nthl1 SWALL:O35980 (EMBL:AB006812) (300 aa) fasta scores: E(): 2e-24, 44.6% id in 213 aa 23612231 Similar to Plasmodium falciparum enoyl-acyl carrier reductase fabI SWALL:Q9BH77 (EMBL:AF338731) (432 aa) fasta scores: E(): 1.5e- 161, 99.53% id in 432 aa, and to Brassica napus enoyl-[acyl-carrier protein] reductase precursor enrb1 SWALL:Q93X64 (EMBL:AJ243089) (387 aa) fasta scores: E(): 6e- 43, 46.7% id in 334 aa, and to Arabidopsis thaliana enoyl-acp reductase enr1 SWALL:Q9M672 (EMBL:AF207593) (390 aa) fasta scores: E(): 4.8e-42, 46.24% id in 333 aa 23612234 High similarity to Pfam:RNB (3.6e-10) domain between codons 1316-2514 Similar to Campylobacter jejuni putative ribonuclease cj0631C SWALL:Q9PHN6 (EMBL:AL139075) blast scores: E(): 3e-16, score: 90 29% id, and to Chlamydia pneumoniae ribonuclease r rnr or vacb or cpn0504 or cp0249 SWALL:RNR_CHLPN (SWALL:Q9Z848) blast scores: E(): 2e-15, score: 87 28% id, and to Arabidopsis thaliana putative 3'-5' exoribonuclease, 3' partial t32e8.1 SWALL:Q9CA26 (EMBL:AC012193) blast scores: E(): 4e-15, score: 87 29% id 23612235 Similar to Trypanosoma cruzi cdc2-related protein kinase 2 tcrk2 SWALL:Q94799 (EMBL:U74763) (301 aa) fasta scores: E(): 9e-08, 40.83% id in 120 aa, and to Dictyostelium discoideum cdc2-like serine/threonine-protein kinase crp crpa or crP SWALL:CC2H_DICDI (SWALL:P34117) (292 aa) fasta scores: E(): 1.1e-07, 44.06% id in 118 aa, and to Leishmania major probable cell division protein kinase 2 homolog crk1 l3856.04 SWALL:Q9GYC3 (EMBL:AL391394) (301 aa) fasta scores: E(): 5.6e-07, 38.33% id in 120 aa 23612237 Pfam hit (2.4e-12) to rrm domain Similar to Arabidopsis thaliana RNA and export factor binding protein 2-i-like protein SWALL:Q9FJE1 (EMBL:AB015475) (239 aa) fasta scores: E(): 7.1e-05, 30.59% id in 134 aa, and to Mus musculus RNA and export factor binding protein 1-ii refbp1 or ref1 SWALL:Q9JJW7 (EMBL:AJ252140) (163 aa) fasta scores: E(): 8.1e-05, 32.58% id in 89 aa, and to Arabidopsis thaliana RNA and export factor binding protein 2-i-like protein SWALL:Q9FJE1 (EMBL:AB015475) blast scores: E(): 5e-08, score: 59 36% id, and to Mus musculus RNA and export factor binding protein 1-ii refbp1 or ref1 SWALL:Q9JJW7 (EMBL:AJ252140) blast scores: E(): 1e-07, score: 57 32% id 23612238 It is possible that the putative intron between the second and third exon in the present gene model does not exist and the reading frame containing the second exon, the third exon and the intervening sequences constituting the second exon of this gene 23612239 Weak HMMSmart hit to catalytic domain of Serine/threonine phosphatase family 2C between codons 1117- 1799; hypothetical protein with PP2C domain 23612240 The product call is based on strong blastp evidence Similar to Homo sapiens pyridoxine kinase pdxk or pkh or pnK SWALL:PDXK_HUMAN (SWALL:O00764) blast scores: E(): 5e-15, score: 84 30% id, and to Dictyostelium discoideum pyridoxal kinase SWALL:Q9GV94 (EMBL:AF136753) blast scores: E(): 2e-22, score: 267 39% id, and to Arabidopsis thaliana pyridoxal kinase-like protein Sos4 sos4 SWALL:Q94EN4 (EMBL:AF400125) blast scores: E(): 5e-17, score: 90 33% id, and to Trypanosoma brucei pyridoxine/pyridoxal/pyridoxamine kinase pdxK SWALL:O15927 (EMBL:U96712) blast scores: E(): 1e-15, score: 86 26% id 23612245 Contains putative von Willebrand factor (vWF) type A domain between codons 336-528 23612248 Similar to Campylobacter jejuni probable malate:quinone oxidoreductase mqo or cj0393C SWALL:MQO_CAMJE (SWALL:P56954) blast scores: E(): 1e-98, score: 917 42% id, and to Campylobacter jejuni probable malate:quinone oxidoreductase mqo or cj0393C SWALL:MQO_CAMJE (SWALL:P56954) (448 aa) fasta scores: E(): 2.7e-72, 44.09% id in 449 aa, and to Helicobacter pylori malate:quinone oxidoreductase mqo or hp0086 SWALL:MQO_HELPY (SWALL:O24913) (450 aa) fasta scores: E(): 3.6e-68, 44.67% id in 432 aa, and to Helicobacter pylori J99 malate:quinone oxidoreductase mqo or jhp0079 SWALL:MQO_HELPJ (SWALL:Q9ZMY5) (450 aa) fasta scores: E(): 6.4e-68, 44.08% id in 431 aa 23612250 Similar to Neurospora crassa mitochondrial import receptor subunit tom40 tom40 or mom38 or b10h4.150 SWALL:OM40_NEUCR (SWALL:P24391) (349 aa) fasta scores: E(): 5.6, 21.54% id in 246 aa, and to Picea mariana isp42-like protein sb41 SWALL:O65070 (EMBL:AF051231) (94 aa) fasta scores: E(): 6.2e-06, 30.76% id in 91 aa, and to Arabidopsis thaliana probable mitochondrial import receptor subunit tom40 homolog tom40 or at3g20000 or mze19.5 SWALL:OM40_ARATH (SWALL:Q9LHE5) (308 aa) fasta scores: E(): 9.2e-05, 24.2% id in 219 aa, and to Oryza sativa similar to isp42-like protein SWALL:Q9SDG4 (EMBL:AP000836) (290 aa) fasta scores: E(): 0.0057, 25.23% id in 107 aa 23612251 Strong Pfam hit (2e-22;codon 25-837) to Adaptin N terminal region Similar to Arabidopsis thaliana alpha-adaptin c homolog SWALL:Q9FGT0 (EMBL:AB024030) blast scores: E(): 3e-22, score: 269 32% id, and to Arabidopsis thaliana alpha-adaptin SWALL:Q9FNI4 (EMBL:AB006699) (1016 aa) fasta scores: E(): 3.7e-15, 21.3% id in 873 aa, and to Schizosaccharomyces pombe putative alpha-adaptin apl3 SWALL:Q9C0W7 (EMBL:AL590882) (878 aa) fasta scores: E(): 6.3e-15, 32.91% id in 237 aa, and to Neurospora crassa related to alpha-adaptin c b12f1.60 SWALL:Q9P3H7 (EMBL:AL390091) (988 aa) fasta scores: E(): 1.6e-13, 20.2% id in 866 aa 23612252 Although it is moderately similar to yeast nuclear segregation protein bfr1, the evidence is not strong enough to call this protein a bfr1 homologue Similar to Saccharomyces cerevisiae nuclear segregation protein bfr1 bfr1 or yor198C SWALL:BFR1_YEAST (SWALL:P38934) (470 aa) fasta scores: E(): 5.1e-07, 23.11% id in 463 aa, and to Schizosaccharomyces pombe similar to yeast nuclear segregation protein bfr1 involved in mitosis and vesicular transport spac458.02C SWALL:Q9P3W6 (EMBL:AL358272) (468 aa) fasta scores: E(): 3.8e-06, 19.77% id in 445 aa 23612254 Similar to Plasmodium falciparum erythrocyte membrane protein 1 pfemp1 SWALL:Q94657 (EMBL:U31083) (2212 aa) fasta scores: E(): 3.4e-163, 41.84% id in 2232 aa, and to Plasmodium falciparum Fcr3-vart11-1 protein fcr3-vart11-1 SWALL:P90580 (EMBL:U67959) (2647 aa) fasta scores: E(): 3.1e-142, 41% id in 2646 aa 23612255 Similar to Plasmodium falciparum rifin pfb0025C SWALL:O96111 (EMBL:AE001367) (304 aa) fasta scores: E(): 1.5e-63, 60.85% id in 304 aa 23612256 Similar to Plasmodium falciparum Pfc0040w,mal3p8.7 protein pfc0040w,mal3p8.7 SWALL:O97328 (EMBL:AL034560) (321 aa) fasta scores: E(): 1.2e-60, 56.66% id in 330 aa 23612257 Similar to Plasmodium falciparum histone h2a SWALL:H2A_PLAFA (SWALL:P40282) (132 aa) fasta scores: E(): 5.1e-50, 100% id in 132 aa, and to Picea abies histone h2a SWALL:H2A_PICAB (SWALL:P35063) (138 aa) fasta scores: E(): 7e-35, 72.93% id in 133 aa, and to Arabidopsis thaliana histone h2a, putative f23h24.9 SWALL:Q9C681 (EMBL:AC079828) (132 aa) fasta scores: E(): 7.9e-35, 72.72% id in 132 aa 23612258 Similar to Plasmodium falciparum histone h3 SWALL:Q27719 (EMBL:U15994) (136 aa) fasta scores: E(): 1.4e-46, 99.26% id in 136 aa, and to Arabidopsis thaliana histon h3 protein t30n20_250 SWALL:CAB96853 (EMBL:AL365234) (136 aa) fasta scores: E(): 1.2e-43, 91.17% id in 136 aa, and to Oryza sativa histone h3 SWALL:AAC78105 (EMBL:AF093633) (136 aa) fasta scores: E(): 1.2e-43, 91.17% id in 136 aa 23612262 Similar to Dictyostelium discoideum 60S ribosomal protein l27a rpl27A SWALL:RL2A_DICDI (SWALL:P48160) (148 aa) fasta scores: E(): 7.8e-41, 69.12% id in 149 aa, and to Mus musculus ribosomal protein l27a rpl27a or l27A SWALL:Q9CQ16 (EMBL:AK010286) (148 aa) fasta scores: E(): 1.1e-40, 65.1% id in 149 aa, and to Rattus norvegicus 60S ribosomal protein l27a rpl27A SWALL:RL2A_RAT (SWALL:P18445) (147 aa) fasta scores: E(): 1.7e-40, 65.3% id in 147 aa, and to Homo sapiens 60S ribosomal protein l27a rpl27A SWALL:AAH05326 (EMBL:U14968) (148 aa) fasta scores: E(): 2.7e-40, 65.1% id in 149 aa 23612263 There is possibility of another small exon between the 3rd and 4th exon in the present gene model 23612264 Similar to Rickettsia prowazekii malate dehydrogenase mdh or rp376 SWALL:MDH_RICPR (SWALL:Q9ZDF3) (314 aa) fasta scores: E(): 6.6e-52, 48.34% id in 302 aa, and to Caulobacter crescentus malate dehydrogenase cc3655 SWALL:Q9A2B1 (EMBL:AE006023) (320 aa) fasta scores: E(): 4.5e-50, 44.87% id in 312 aa, and to Rhizobium leguminosarum malate dehydrogenase mdH SWALL:MDH_RHILV (SWALL:O33525) (320 aa) fasta scores: E(): 2.8e-49, 44.51% id in 301 aa 23612265 Weak Pfam hit to Rhomboid family between codons 96- 235 23612267 Although blasp shows similarity to DNA-directed RNA polymerase of P. falciparum, the evidence is not strong enough to annotate this gene product as similar to DNA- directed RNA polymerase Similar to Plasmodium falciparum DNA-directed RNA polymerase beta chain rpoB SWALL:RPOB_PLAFA (SWALL:P21421) blast scores: E(): 5e-06, score: 55 25% id 23612268 Does not match exactly with the submitted Plasmodium falciparum N-acetylglucosamine transferase gpi1 sequence at the C-terminal end (SWALL:Q9GRI3 (EMBL:AJ249657)); one additional potential 5'-end exon is possible Similar to Plasmodium falciparum N-acetylglucosamine transferase gpi1 SWALL:Q9GRI3 (EMBL:AJ249657) (669 aa) fasta scores: E(): 3.2e-201, 97.35% id in 643 aa, and to Schizosaccharomyces pombe N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein gpi1 gpi1 or spbc30d10.11 SWALL:GPI1_SCHPO (SWALL:O14357) (653 aa) fasta scores: E(): 6.6e-13, 25.19% id in 385 aa, and to Saccharomyces cerevisiae N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein gpi1 gpi1 or ygr216C SWALL:GPI1_YEAST (SWALL:P53306) (609 aa) fasta scores: E(): 4.7e-12, 27.19% id in 342 aa, and to Mus musculus mgpi1p pigq or gpi1h or mgpi1 SWALL:O35120 (EMBL:AB008895) (581 aa) fasta scores: E(): 5.1e-12, 26.15% id in 325 aa, and to Homo sapiens C407a10.1 c407a10.1 SWALL:Q9UJH4 (EMBL:Z98883) (583 aa) fasta scores: E(): 1e-11, 25.3% id in 328 aa 23612269 Blast hit to AAA family of ATP-ases (2.0e-14), obtained using SMART web server; The existence of the last exon is less certain; There is possiblity that the last 9 exons might form a separate hypothetical gene 23612270 The first 2 exons are uncertain 23612272 Alternative start codon possible at 14 amino acids downstream of the present start codon; hypothetical protein (fragment) 23612273 The 3' end of the protein is missing as the contig ends; annotation is based on the partial sequence; asparagine-rich protein 23612274 Similar to Dictyostelium discoideum cell division cycle protein 48 cdcD SWALL:P90532 (EMBL:U83085) (793 aa) fasta scores: E(): 1.8e-104, 61.49% id in 496 aa, and to Capsicum annuum cell division cycle protein 48 homolog cafP SWALL:CC48_CAPAN (SWALL:Q96372) (805 aa) fasta scores: E(): 9e- 103, 60.27% id in 501 aa, and to Glycine max cell division cycle protein 48 homolog cdc48 SWALL:CC48_SOYBN (SWALL:P54774) blast scores: E(): e-158, score: 1421 62% id, and to Arabidopsis thaliana cell division cycle protein 48 homolog cdc48 or at3g53230 or f8a24.11 SWALL:CC48_ARATH (SWALL:P54609) blast scores: E(): e- 152, score: 1377 71% id 23612275 Similar to Saccharomyces cerevisiae peroxisomal-coenzyme a synthetase fat2 or pcs60 or ybr222c or ybr1512 SWALL:FAT2_YEAST (SWALL:P38137) (543 aa) fasta scores: E(): 2.9e-09, 29.31% id in 655 aa, and to Capsicum annuum putative acyl-coa synthetase SWALL:Q946Z2 (EMBL:AF354454) (523 aa) fasta scores: E(): 2e-10, 29.64% id in 614 aa, and to Schizosaccharomyces pombe putative coenzyme a synthetase spcc1827.03C SWALL:O74976 (EMBL:AL023777) (512 aa) fasta scores: E(): 3.6e-06, 28.38% id in 627 aa 23612280 SMART and ProfileScan hit to U1-type zinc finger domain in codons 51-85 Similar to Drosophila melanogaster Cg10754 protein cg10754 SWALL:Q9VU15 (EMBL:AE003540) (264 aa) fasta scores: E(): 2e-43, 55.06% id in 227 aa, and to Homo sapiens splicing factor 3a subunit 2 sf3a2 or sap62 SWALL:S3A2_HUMAN (SWALL:Q15428) (464 aa) fasta scores: E(): 7.3e-42, 54.26% id in 223 aa, and to Arabidopsis thaliana putative spliceosome associated protein at2g32600 SWALL:Q940T1 (EMBL:AC004681) (277 aa) fasta scores: E(): 1.3e-36, 49.76% id in 211 aa, and to Schizosaccharomyces pombe similar to mouse sf3a spliceosome complex protein sap62 spbc21c3.05 SWALL:Q9P7L8 (EMBL:AL157918) (217 aa) fasta scores: E(): 1.8e-34, 45.16% id in 217 aa 23612285 Similar to Plasmodium falciparum merozoite surface protein 8 msp8 SWALL:Q964F7 (EMBL:AF325157) (596 aa) fasta scores: E(): 1.1e-13, 26.15% id in 604 aa 23612286 Contains WD40 repeat domains Similar to Homo sapiens cleavage stimulation factor, 50 kDa subunit cstf1 SWALL:CST1_HUMAN (SWALL:Q05048) (431 aa) fasta scores: E(): 1.5e-09, 25.7% id in 319 aa, and to Homo sapiens cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kd SWALL:AAH07425 (EMBL:BC007425) blast scores: E(): 6e-22, score: 264 29% id, and to Hordeum vulgare putative cleavage stimulation factor subunit 1 SWALL:Q9ARL8 (EMBL:AY013246) blast scores: E(): 1e-17, score: 93 27% id, and to Arabidopsis thaliana cleavage stimulation factor subunit 1-like protein SWALL:Q9FME6 (EMBL:AB008269) blast scores: E(): 7e-14, score: 80 24% id 23612288 Weak Pfam hit to DNAJ domain 23612289 Although Blastp evidence suggests that this protein could be related to RNA polymerase sigma factors from Anabaena and other genera, there is no further supporting evidence in FASTA search or HMMSmart and InterPro searches Similar to Anabaena sp. RNA polymerase sigma-b factor sigb or all7615 SWALL:BAB77258 (EMBL:M95760) blast scores: E(): 9e-06, score: 54 24% id, and to Thermotoga maritima RNA polymerase sigma factor rpod rpod or siga or tm1451 SWALL:RPSD_THEMA (SWALL:P77994) blast scores: E(): 9e-04, score: 47 22% id, and to Physcomitrella patens ppSig2 sig2 SWALL:Q9AYR7 (EMBL:AB046872) blast scores: E(): 0.001, score: 47 20% id, and to Guillardia theta RNA-polymerase sigma factor rpoD SWALL:Q98RZ3 (EMBL:AF165818) blast scores: E(): 0.002, score: 46 21% id 23612291 Strong (4.6e-108;codon 8-214) Pfam hit to SOR/SNZ family Similar to Arabidopsis thaliana pyridoxine biosynthesis protein-like t10o8_120 SWALL:Q9M032 (EMBL:AL161746) (309 aa) fasta scores: E(): 4.2e-66, 62.1% id in 285 aa, and to Phaseolus vulgaris putative pyridoxine biosynthetic enzyme pdx1 SWALL:Q9FT25 (EMBL:AY007525) (312 aa) fasta scores: E(): 7.7e-65, 61.05% id in 285 aa, and to Hevea brasiliensis ethylene-inducible protein hever er1 SWALL:ER1_HEVBR (SWALL:Q39963) (309 aa) fasta scores: E(): 2.1e-64, 60.7% id in 285 aa, and to Schizosaccharomyces pombe hypothetical protein c29b12.04 in chromosome i spac29b12.04 SWALL:YEM4_SCHPO (SWALL:O14027) (296 aa) fasta scores: E(): 3.2e-63, 62.85% id in 280 aa 23612293 The mRNA is expressed only in sexual stage in female gametocytes (PMID: 8538689) Similar to Plasmodium falciparum Pfs77 protein pfs77 SWALL:Q27435 (EMBL:Z37724) (664 aa) fasta scores: E(): 0, 100% id in 664 aa 23612296 Pfam match to NAC domain Similar to Drosophila melanogaster nacalpha protein nac-alpha or oxen or nacalpha or cg8759 SWALL:O16813 (EMBL:AE003821) (217 aa) fasta scores: E(): 2.6e-14, 35.71% id in 154 aa, and to Arabidopsis thaliana nascent polypeptide associated complex alpha chain t2e22.29 SWALL:Q9LHG9 (EMBL:AP002047) (203 aa) fasta scores: E(): 9.7e-14, 33.33% id in 186 aa, and to Pinus taeda nascent polypeptide associated complex alpha chain SWALL:Q9M612 (EMBL:AF220200) (205 aa) fasta scores: E(): 1.7e- 13, 31.72% id in 186 aa, and to Homo sapiens nascent polypeptide associated complex alpha subunit alpha naC SWALL:Q13765 (EMBL:X80909) (215 aa) fasta scores: E(): 5.2e-13, 33.76% id in 154 aa 23612297 There is similarity to smart HATPse_c domain but the similarity and results from other searches are not conclusive enough to annotate this protein as a histine kinase-like ATP-ases 23612298 FEATURE_NAME needs adding 23612300 This conserved hypothetical protein has a long N- terminal extension in addition to the conserved amino acid residues Similar to Arabidopsis thaliana hypothetical 65.5 kDa protein f28p5.4 SWALL:Q9C7H2 (EMBL:AC069273) (601 aa) fasta scores: E(): 1.9e-51, 46.72% id in 366 aa, and to Drosophila melanogaster Cg6550 protein cg6550 SWALL:Q9V812 (EMBL:AE003803) (552 aa) fasta scores: E(): 9.5e-48, 40.79% id in 478 aa, and to Mus musculus hypothetical 65.3 kDa protein SWALL:Q91WE6 (EMBL:BC016073) (578 aa) fasta scores: E(): 9.2e-47, 45.06% id in 375 aa, and to Pyrococcus abyssi hypothetical protein Pab1134 pab1134 SWALL:YB34_PYRAB (SWALL:Q9UXX9) (425 aa) fasta scores: E(): 3.1e-31, 35.06% id in 365 aa 23612303 match to PfaDd2|0413c3|1999.12.28|EST|UFla 10..142 blast score 248 percent identity 99; Similar to Treponema pallidum hypothetical protein Tp0032 tp0032 SWALL:Y032_TREPA (SWALL:O83075) (266 aa) fasta scores: E(): 6.1e-11, 26.18% id in 275 aa; hypothetical protein, conserved 23612305 Similar to Schizosaccharomyces pombe putative leucyl-trna synthetase, cytoplasmic spac26f1.13C SWALL:SYLC_SCHPO (SWALL:Q10490) (1111 aa) fasta scores: E(): 7.9e-20, 31.32% id in 1210 aa, and to Saccharomyces cerevisiae leucyl-trna synthetase, cytoplasmic cdc60 or ypl160w or p2564 SWALL:SYLC_YEAST (SWALL:P26637) (1090 aa) fasta scores: E(): 2.4e-16, 30.63% id in 1172 aa, and to Candida albicans cytosolic leucyl-trna synthetase cdc60 SWALL:Q9HGT2 (EMBL:AF293346) (1097 aa) fasta scores: E(): 3.9e-16, 29.5% id in 1281 aa, and to Neurospora crassa leucyl-trna synthetase, cytoplasmic leu-6 SWALL:SYLC_NEUCR (SWALL:P10857) (1123 aa) fasta scores: E(): 6.5e-16, 30.94% id in 1186 aa, and to Arabidopsis thaliana putative leucyl-trna synthetase f21m12.1 SWALL:Q93ZU0 (EMBL:AY056261) (980 aa) fasta scores: E(): 1.2e-15, 30.83% id in 1200 aa 23612306 Asparagine-rich 23612307 Similar to Plasmodium falciparum chorismate synthase aroC SWALL:O15864 (EMBL:AF008549) (527 aa) fasta scores: E(): 6.1e-216, 99.81% id in 527 aa 23612309 Similar to Anabaena sp. ferredoxin--NADP reductase petH SWALL:FENR_ANASO (SWALL:P21890) (440 aa) fasta scores: E(): 5.4e-13, 27.66% id in 347 aa, and to Synechococcus elongatus ferredoxin-NADP+ oxidoreductase petH SWALL:Q93RE3 (EMBL:AB049339) (386 aa) fasta scores: E(): 6.4e-13, 26.99% id in 326 aa, and to Zea mays ferredoxin-NADP reductase precursor SWALL:Q41736 (EMBL:U10418) (327 aa) fasta scores: E(): 1.3e-12, 30.29% id in 340 aa, and to Oryza sativa ferredoxin--NADP reductase, leaf isozyme, chloroplast precursor SWALL:FENR_ORYSA (SWALL:P41344) (362 aa) fasta scores: E(): 1.4e-12, 28.73% id in 341 aa 23612310 Some domain similarity to human and rat jagged2 protein; Weak similarity to EGF-like domains; cysteine- rich protein Similar to Homo sapiens jagged 2 precursor jag2 SWALL:Q9UNK8 (EMBL:AF020201) blast scores: E(): 4e-09, score: 63 30% id, and to Rattus norvegicus jagged 2 jag2 SWALL:P97607 (EMBL:U70050) blast scores: E(): 7e-09, score: 62 32% id 23612311 Similar to Arabidopsis thaliana putative RNA-binding protein mei2 at1g29400 or f15d2.30 SWALL:AAL32691 (EMBL:AY070368) (800 aa) fasta scores: E(): 1.2e-13, 47.58% id in 124 aa, and to Schizosaccharomyces pombe meiosis protein mei2 mei2 or spac27d7.03C SWALL:MEI2_SCHPO (SWALL:P08965) (750 aa) fasta scores: E(): 1.5e-13, 46.37% id in 138 aa 23612312 Similar to Plasmodium falciparum fe-superoxide dismutase soD SWALL:Q27740 (EMBL:Z49819) (198 aa) fasta scores: E(): 1.4e-31, 50.57% id in 174 aa, and to Plasmodium vivax superoxide dismutase [mn/fe] SWALL:Q9Y1A9 (EMBL:AF139529) (198 aa) fasta scores: E(): 1.4e-31, 50.57% id in 174 aa 23612313 Contains Khomology RNA-binding domain, and a putative Zn-finger C2HC domain Similar to Drosophila melanogaster sf1 protein sf1 or cg5836 SWALL:Q9U1J9 (EMBL:AJ243904) (773 aa) fasta scores: E(): 2.7e-26, 32.73% id in 388 aa, and to Arabidopsis thaliana similarity to transcription or splicing factor SWALL:Q9LU44 (EMBL:AB023044) (804 aa) fasta scores: E(): 2.7e-24, 31.76% id in 403 aa, and to Homo sapiens sf1-bo isoform SWALL:Q92744 (EMBL:Y08766) (638 aa) fasta scores: E(): 3.4e-20, 34.03% id in 379 aa, and to Schizosaccharomyces pombe putative transcription or splicing factor spcc962.06c or bbp/sf1 SWALL:O74555 (EMBL:AL031323) blast scores: E(): 1e-35, score: 380 36% id 23612314 Similar to Saccharomyces cerevisiae ATP-dependent RNA helicase suv3, mitochondrial precursor suv3 or ypl029w or lpb2W SWALL:SUV3_YEAST (SWALL:P32580) (737 aa) fasta scores: E(): 1.7e-15, 25.58% id in 641 aa, and to Arabidopsis thaliana mitochondrial RNA helicase-like protein SWALL:Q9FLF1 (EMBL:AB010077) (769 aa) fasta scores: E(): 4.3e-15, 28.14% id in 469 aa, and to Homo sapiens putative ATP-dependent mitochondrial RNA helicase suv3 SWALL:O43630 (EMBL:AF042169) (786 aa) fasta scores: E(): 1.4e-12, 26.86% id in 469 aa, and to Schizosaccharomyces pombe putative mitochondrial ATP-dependent RNA helicase c637.11 precursor spac637.11 SWALL:O94445 (EMBL:AL034583) blast scores: E(): 7e-29, score: 325 42% id 23612315 Pfam hit (2.2e-35;codon 2160-2399) to Protein kinase domain and HMMSmart hit (1.6e-13;codon 2042-2397)to Tyrosine kinase catalytic domain in the C-terminus of the protein Similar to Arabidopsis thaliana mek kinase map3kA SWALL:Q9ZRF7 (EMBL:U58918) blast scores: E(): 6e-17, score: 92 30% id, and to Oryza sativa similar to mitogen-activated protein kinases dupr11.32 SWALL:Q9LLM7 (EMBL:AF172282) blast scores: E(): 1e-16, score: 92 29% id 23612316 Similar to Caenorhabditis elegans ribonuclease hi large subunit rnh2 or t13h5.7 SWALL:RNHL_CAEEL (SWALL:Q9U6P6) (297 aa) fasta scores: E(): 1.5e-41, 46.52% id in 273 aa, and to Drosophila melanogaster probable ribonuclease hi large subunit cg13690 SWALL:RNHL_DROME (SWALL:Q9VPP5) (347 aa) fasta scores: E(): 1.2e-43, 47.61% id in 273 aa, and to Arabidopsis thaliana probable ribonuclease hi large subunit at2g25100 or f13d4.60 SWALL:RNHL_ARATH (SWALL:Q9SEZ6) (253 aa) fasta scores: E(): 2.6e-40, 50.42% id in 234 aa, and to Schizosaccharomyces pombe probable ribonuclease hi large subunit spac4g9.02 SWALL:RNHL_SCHPO (SWALL:Q10236) (326 aa) fasta scores: E(): 1.1e-31, 41.44% id in 263 aa 23612317 Similar to Plasmodium falciparum hexokinase hK SWALL:HXK_PLAFA (SWALL:Q02155) (493 aa) fasta scores: E(): 2.5e-209, 99.79% id in 493 aa 23612322 With RING finger domain Similar to Drosophila melanogaster putative apc11 anaphase-promoting complex subunit lmg or cg18042 SWALL:Q9U1J4 (EMBL:AJ251510) (85 aa) fasta scores: E(): 1.6e-12, 40.22% id in 87 aa, and to Arabidopsis thaliana anaphase promoting complex subunit 11 SWALL:Q940X6 (EMBL:AY052402) (84 aa) fasta scores: E(): 6.8e- 12, 37.64% id in 85 aa, and to Mus musculus anaphase promoting complex subunit 11 anapc11 SWALL:AN11_MOUSE (SWALL:Q9CPX9) (84 aa) fasta scores: E(): 4e-11, 35.29% id in 85 aa 23612323 ISWI is a component of the nucleosome remodelling factor complex, a protein complex that facilitates the perturbation of chromatin structure in vitro in an ATP- dependant manner. The hydrolysis of ATP during the remodelling of chromatin is likely to be mediated by ISWI, releasing inorganic phosphate Similar to Xenopus laevis imitation switch IswI iswI SWALL:Q9DF71 (EMBL:AF292095) (1046 aa) fasta scores: E(): 3.5e-16, 42.35% id in 229 aa, and to Drosophila melanogaster iswi protein iswi or cg8625 SWALL:ISWI_DROME (SWALL:Q24368) blast scores: E(): 3e-40, score: 425 45% id, and to Drosophila melanogaster iswi protein iswi or cg8625 SWALL:ISWI_DROME (SWALL:Q24368) (1027 aa) fasta scores: E(): 2.2e- 17, 43.31% id in 217 aa 23612324 First exon is uncertain; the S. pombe, human and rat N-acetylglucosaminyl- phosphatidylinositol de-n-acetylasehomologues have a DUF158 pfam domain whereas this protein does not have a pfam hit Similar to Schizosaccharomyces pombe probable N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase spapb2b4.01C SWALL:PIGL_SCHPO (SWALL:Q9HDW9) (248 aa) fasta scores: E(): 7.4e-19, 38.12% id in 181 aa, and to Homo sapiens N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase pigL SWALL:PIGL_HUMAN (SWALL:Q9Y2B2) (252 aa) fasta scores: E(): 3.4e-13, 29.7% id in 202 aa, and to Rattus norvegicus N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase pigL SWALL:PIGL_RAT (SWALL:O35790) (252 aa) fasta scores: E(): 3.9e-13, 30.69% id in 202 aa 23612325 Alternative exon-intron boundaries possible for the internal exons of this protein 23612326 BLAST hit to AAA ATP-ase (4.0e-06) in schnipsel database, domain similarity is between residues 21 and 192; no significant hits to AAA family ATP-ases in FASTA or BLASTP searches 23612328 Weak hit (7.6e-02) to pfam PAP2 domain (type 2 phosphatidic acid phosphatase superfamily), contains 2 putative transmembrane domains 23612329 The existence of the first exon not certain; alternate model for the same gene could be single exon structure with the putative start codon 17 amino acid upstream of the 5' end of the second exon 23612330 Weak blast hits to kinases, in addition to other hits to different proteins 23612331 Annotation is based on BLASTP search results and pfam hit to DNA_pol_A domain (3.9e-08) Similar to Bacillus caldotenax DNA polymerase i polA SWALL:DPO1_BACCA (SWALL:Q04957) blast scores: E(): 4e-28, score: 320 30% id, and to Thermotoga maritima DNA-directed dna polymerase i tm1619 SWALL:Q9X1V4 (EMBL:AE001805) blast scores: E(): 5e-28, score: 319 30% id, and to Bacillus stearothermophilus DNA polymerase i polg1 SWALL:O24675 (EMBL:U93028) blast scores: E(): 3e-27, score: 312 29% id, and to Clostridium acetobutylicum DNA polymerase i, pola cac1098 SWALL:Q97K23 (EMBL:AE007626) blast scores: E(): 2e-26, score: 305 29% id 23612334 In human, different isoforms such as alpha, beta, gamma exits (see in PMID:8302877); this protein shows high similarity to all these isoforms and that is why not annotated to a particular isoform Similar to Bos taurus poly papola or paP SWALL:PAP_BOVIN (SWALL:P25500) (738 aa) fasta scores: E(): 8.1e-56, 38.83% id in 533 aa, and to Homo sapiens poly papola or paP SWALL:PAP_HUMAN (SWALL:P51003) (660 aa) fasta scores: E(): 8.4e-56, 38.64% id in 533 aa, and to Xenopus laevis poly SWALL:PAP3_XENLA (SWALL:P51006) (400 aa) fasta scores: E(): 1.7e-55, 47.5% id in 341 aa, and to Homo sapiens poly papolb or papT SWALL:PAPB_HUMAN (SWALL:Q9NRJ5) (636 aa) fasta scores: E(): 5.7e-55, 38.7% id in 509 aa 23612339 Similar to Brassica napus putative pod-specific dehydrogenase sac25 SWALL:P81259 (EMBL:X74225) (320 aa) fasta scores: E(): 2.3e-21, 30.26% id in 304 aa, and to Oryza sativa p0009g03.18 protein p0009g03.18 or p0030h07.1 SWALL:Q9LGI8 (EMBL:AP002522) (321 aa) fasta scores: E(): 4.8e-21, 28.89% id in 308 aa, and to Arabidopsis thaliana putative oxidoreductase at2g37540 SWALL:O80924 (EMBL:AC004684) (321 aa) fasta scores: E(): 8.8e-20, 30.87% id in 285 aa 23612340 Asparagine-rich 23612341 Alternative gene structure exist for the first 2 exons. It is possible that the first 2 exons don't exist and there is a little first exon of 3 amino acids (MIK) before the third exon in the present model Similar to Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase i/ii fabb/fabF SWALL:Q965D4 (EMBL:AF237575) (257 aa) fasta scores: E(): 1.3e-98, 99.22% id in 257 aa, and to Clostridium acetobutylicum 3-oxoacyl- cac3573 SWALL:Q97DA7 (EMBL:AE007854) (411 aa) fasta scores: E(): 5.3e-78, 48.66% id in 413 aa, and to Aquifex aeolicus 3-oxoacyl-[acyl-carrier-protein] synthase ii fabf or aq_1717 SWALL:O67612 (EMBL:AE000752) (415 aa) fasta scores: E(): 8.5e-74, 47.83% id in 416 aa 23612342 SMART domain hit to Sec14 (2.54e-07), a domain found in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p) 23612345 Conserved, human myg1-like protein Similar to Homo sapiens myg1 protein c12orf10 SWALL:MYG1_HUMAN (SWALL:Q9HB07) (376 aa) fasta scores: E(): 3.1e-49, 43.47% id in 322 aa, and to Mus musculus Myg1 protein myg1 SWALL:MYG1_MOUSE (SWALL:Q9JK81) (380 aa) fasta scores: E(): 6.4e-49, 41.92% id in 322 aa, and to Arabidopsis thaliana gamm1 protein-like SWALL:Q9FHY6 (EMBL:AB017067) (346 aa) fasta scores: E(): 1.5e-44, 39.56% id in 321 aa, and to Schizosaccharomyces pombe hypothetical protein c694.04c in chromosome i spac694.04C SWALL:YIW4_SCHPO (SWALL:Q9P7T6) (324 aa) fasta scores: E(): 5.7e-42, 40% id in 325 aa 23612346 Similar to Eimeria tenella pyruvate kinase pyK SWALL:KPYK_EIMTE (SWALL:O44006) (531 aa) fasta scores: E(): 5.2e-128, 64.96% id in 508 aa, and to Toxoplasma gondii pyruvate kinase pK SWALL:Q969A2 (EMBL:AB050726) (531 aa) fasta scores: E(): 8.8e-132, 66.79% id in 506 aa, and to Arabidopsis thaliana pyruvate kinase SWALL:Q9FFP6 (EMBL:AB005234) (510 aa) fasta scores: E(): 2.7e-83, 47.96% id in 515 aa 23612349 There are 8 putative ankyrin repeat-like elements in the sequence as indicated by Pfam search results 23612350 Hypothetical protein with similarity to troponin c- like proteins; weak pfam hit (2.0e-02) to EF-hand domain: a domain associated with signalling or buffering / transport proteins; existence of the first 2 exons uncertain Similar to Homo sapiens troponin c, slow skeletal and cardiac muscles tnnc1 or tnnC SWALL:TPCC_HUMAN (SWALL:P02590) (161 aa) fasta scores: E(): 0.023, 26.66% id in 135 aa, and to Toxoplasma gondii myosin light chain tgmlc1 SWALL:Q95UJ7 (EMBL:AY048862) (213 aa) fasta scores: E(): 0.024, 24.29% id in 107 aa, and to Coturnix coturnix japonica troponin c, slow skeletal and cardiac muscles tnnc1 SWALL:TPCC_COTJA (SWALL:P05936) (161 aa) fasta scores: E(): 0.026, 25.92% id in 135 aa 23612351 Pfam and HMMSmart hit to zinc finger and RINg finger domains respectively Similar to Arabidopsis thaliana putative c3hc4-type ring zinc finger protein at2g23780 SWALL:O64824 (EMBL:AC004482) blast scores: E(): 1e-17, score: 92 57% id 23612352 2 probable transmembrane helices predicted by TMHMM2.0 at aa 71-93 and 168-185 Similar to Saccharomyces cerevisiae mitochondrial import inner membrane translocase subunit tim22 tim22 or ydl217c or d0884 SWALL:IM22_YEAST (SWALL:Q12328) (207 aa) fasta scores: E(): 4.8e-07, 38.31% id in 107 aa, and to Neurospora crassa probable tim22, subunit of the tim22-complex 99h12.010 SWALL:Q9HEE8 (EMBL:AL451018) (194 aa) fasta scores: E(): 6.6e-09, 38.79% id in 116 aa, and to Mus musculus tim22 preprotein translocase timm22 or tim22 SWALL:Q9JKW2 (EMBL:AF223950) (194 aa) fasta scores: E(): 1.4e-06, 30.76% id in 143 aa, and to Rattus norvegicus Tim22 preprotein translocase tim22 SWALL:Q9JKW1 (EMBL:AF223951) (190 aa) fasta scores: E(): 1.8e-06, 30.76% id in 143 aa 23612353 Pfam hit (1.4e-34;codon 5-169) to ThiJ/PfpI family. This family includes ThiJ a thiamine biosynthesis enzyme that catalyses the phosphorylation of hydroxymethylpyrimidine (HMP) to HMPmonophosphate.This family appears to be distantly related to Glutamine amidotransferases GATase. Similar to Escherichia coli 4-methyl-5 thij or b0424 SWALL:THIJ_ECOLI (SWALL:Q46948) (196 aa) fasta scores: E(): 7.1e-18, 35.63% id in 188 aa, and to Drosophila melanogaster cg1349 protein dj-1-beta or cg1349 SWALL:Q9VA37 (EMBL:AE003775) (187 aa) fasta scores: E(): 1.9e-22, 42.16% id in 185 aa, and to Yersinia pestis 4-methyl-5 thij or ypo3172 SWALL:CAC92407 (EMBL:AJ414155) (196 aa) fasta scores: E(): 2.2e-19, 38.74% id in 191 aa, and to Salmonella typhi 4-methyl-5 sty0472 SWALL:CAD08889 (EMBL:AL627266) (196 aa) fasta scores: E(): 2.4e-17, 35.97% id in 189 aa 23612355 Alternate start site possible at 12 amino acids downsteam from the existing start site as indicated by the submitted P. falciparum transportin sequence (SWALL:BAB78507 (EMBL:AB039843)) Similar to Plasmodium falciparum transportin pftrN SWALL:BAB78507 (EMBL:AB039843) (1136 aa) fasta scores: E(): 0, 99.64% id in 1136 aa, and to Xenopus laevis transportin SWALL:O93335 (EMBL:AF059614) (885 aa) fasta scores: E(): 1.1e-32, 26.01% id in 1111 aa, and to Homo sapiens importin beta-2 subunit kpnb2 or trn or mip1 SWALL:IMB2_HUMAN (SWALL:Q92973) (890 aa) fasta scores: E(): 5.8e-33, 25.4% id in 1118 aa, and to Drosophila melanogaster transportin trn or cg7398 SWALL:O76331 (EMBL:AF059613) (893 aa) fasta scores: E(): 1.8e-32, 25.56% id in 1064 aa 23612356 Other common names include:Acetyl-CoA synthetase, Acyl-activating enzyme, Acetate thiokinase, Acetyl- activating enzyme, Acetate--coa ligase Similar to Cryptosporidium parvum acetyl-coenzyme a synthetase acS SWALL:ACSA_CRYPV (SWALL:Q27549) (694 aa) fasta scores: E(): 1.8e-76, 36.88% id in 976 aa, and to Rhodobacter capsulatus acetyl-coenzyme a synthetase acS SWALL:ACSA_RHOCA (SWALL:O68040) (656 aa) fasta scores: E(): 7.3e-73, 35.61% id in 935 aa, and to Pseudomonas aeruginosa acetyl-coenzyme a synthetase acsb or pa4733 SWALL:Q9HV66 (EMBL:AE004887) (645 aa) fasta scores: E(): 5.1e-70, 35.16% id in 927 aa, and to Solanum tuberosum acetyl-coa synthetase acS SWALL:Q9ZR69 (EMBL:X98506) (631 aa) fasta scores: E(): 6.4e-70, 34.94% id in 933 aa 23612357 Weak SMART hit (3.56e-02) to POP4 domain:a domain found in a protein subunit of human RNase MRP and RNase P ribonucleoprotein complexes and archaeal proteins. 23612358 In many bacteria, a similar protein has been annotated as hypothetical protein as they don't show pfam hit to PTPS domain; pfam hit (8.7e-04) to PTPS domain Similar to Methanococcus jannaschii hypothetical protein Mj1272 mj1272 SWALL:YC72_METJA (SWALL:Q58668) (163 aa) fasta scores: E(): 3.4e-11, 32.66% id in 150 aa, and to Clostridium acetobutylicum 6-pyruvoyl-tetrahydropterin synthase cac3624 SWALL:Q97D56 (EMBL:AE007858) (136 aa) fasta scores: E(): 0.0017, 34.88% id in 86 aa, and to Staphylococcus aureus sa0666 protein sav0711 or sa0666 or mw0673 SWALL:Q99VR2 (EMBL:AP003360) (139 aa) fasta scores: E(): 0.003, 29.82% id in 114 aa 36329003657 Frameshift at the C-terminal region of this protein between amino acid positions 8210 and 8220, immediately after the amino acid sequence LSGGKKDKRNK Frame-shifted from the previous gene; contains possible ankyrin repeats 23612359 This pfPK4 is nearly identical to published pfPK4 sequence (SWALL:O43948 (EMBL:X94118); PMID: 9371731)) at the last 1123 amino acids at the C-terminal end except in the middle where there are 42 amino acids extra in the present gene model. It appears that the published pfPK4 could be a part of a continuous open reading frame as shown in this gene model. The published pfPK4 sequence starts with the following amino acid string sequence MKKRIRSSYK, which maps at amino acid position ~1190;the additional 42 amino acids that are not there in the published sequence maps between amino acid positions 2520 and 2570 respectively with starting and ending amino acid strings of GDKNGLDGD and LDDNTKKLD respectively; There is possibility to have an alternate start site, 134 amino acids downstream of the present start site with the following amino acid string:MINILSND Similar to Plasmodium falciparum Pk4 protein kinase pk4 SWALL:O43948 (EMBL:X94118) (1123 aa) fasta scores: E(): 3.6e-180, 94.07% id in 1165 aa 23612360 4 putative transmembrane domains present; Pfam hit (4.6e-13) to CDP_OH_P_transf domain (CDP-alcohol phosphatidyltransferase); Similar to Dictyostelium discoideum LipB lipB SWALL:O15734 (EMBL:AF019108) (399 aa) fasta scores: E(): 5.5e-20, 27.79% id in 403 aa, and to Pimpinella brachycarpa aminoalcoholphosphotransferase SWALL:O04189 (EMBL:U96439) (389 aa) fasta scores: E(): 4.8e-18, 27.5% id in 360 aa, and to Homo sapiens choline/ethanolaminephosphotransferase cept1 SWALL:Q9Y6K0 (EMBL:AF068302) (416 aa) fasta scores: E(): 1.8e-17, 29.47% id in 380 aa, and to Arabidopsis thaliana aminoalcoholphosphotransferase aapt1 or f13b4.5 or at1g13560 SWALL:O82567 (EMBL:AF091843) (389 aa) fasta scores: E(): 1.2e-15, 24.73% id in 376 aa, and to Brassica campestris aminoalcoholphosphotransferase aapt1 SWALL:O04178 (EMBL:U96713) (389 aa) fasta scores: E(): 1.9e-15, 25% id in 376 aa, and to Schizosaccharomyces pombe putative ethanolaminephosphotransferase spac22a12.10 SWALL:O13901 (EMBL:Z99295) blast scores: E(): 6e-24, score: 279 38% id 23612363 Contains possible DNA-binding domain; weak similarity (1.26e-01) to HMMSMART SANT domain; SANT domain has been referred in the literature as SWI3, ADA2, N-CoR and TFIIIB DNA-binding domains; InterPro weak hit to myb-DNA binding domain Similar to Mus musculus DNA methyltransferase 1-associated protein 1 dmap1 or mmtR SWALL:AAL31640 (EMBL:AF265229) (468 aa) fasta scores: E(): 5.1e-07, 24.32% id in 407 aa 23612365 Strong hit (3.6e-21) to pfam GatB_N domain; contains several repeat units 23612367 Pfam hit (8.3e-06) to acetyltransferase domain (between amino acid positions 165-247) but FASTA and BLASTP did not produe any significant hit to any acetyltransferases 23612368 Similar to Drosophila melanogaster Cg3714 protein cg3714 SWALL:Q9VQX4 (EMBL:AE003577) (541 aa) fasta scores: E(): 6e-36, 37.35% id in 530 aa, and to Arabidopsis thaliana hypothetical 47.4 kDa protein at4g36940 SWALL:O23191 (EMBL:Z99707) (458 aa) fasta scores: E(): 1e-24, 37.92% id in 472 aa, and to Caenorhabditis elegans hypothetical 57.8 kDa protein y54g2a.17 SWALL:AAK68525 (EMBL:AC024817) (511 aa) fasta scores: E(): 2.3e-24, 38.61% id in 492 aa, and to Borrelia burgdorferi hypothetical protein Bb0635 bb0635 SWALL:O51580 (EMBL:AE001165) (481 aa) fasta scores: E(): 5.7e-24, 33.71% id in 528 aa 23612369 Similar to Trypanosoma cruzi Tcj2 protein tcj2 SWALL:Q26952 (EMBL:L42549) (399 aa) fasta scores: E(): 3.4e-32, 35.54% id in 346 aa, and to Mus musculus DNAJ homolog subfamily a member 4 dnaja4 SWALL:DJA4_MOUSE (SWALL:Q9JMC3) (397 aa) fasta scores: E(): 2.8e-31, 34.67% id in 349 aa, and to Cercopithecus aethiops DNAJ-like protein dj2 SWALL:Q95JF4 (EMBL:AF395203) (397 aa) fasta scores: E(): 7.3e-31, 36% id in 350 aa, and to Homo sapiens DNAJ homolog subfamily a member 1 dnaja1 or hsj2 or hspf4 or dnaj2 or hdj2 SWALL:AAH08182 (EMBL:D13388) (397 aa) fasta scores: E(): 8.3e-31, 35.71% id in 350 aa 23612370 Pfam hit (4.7e-17) to LACT domain, Lecithin:cholesterol acyltransferase (LACT) also known as phosphatidylcholine-sterol acyltransferase (EC: 2.3.1.43), is involved in extracellular metabolism of plasma lipoproteins, including cholesterol. It esterifies the free cholesterol transported in plasma lipoproteins, and is activated by apolipoprotein A-I in human Similar to Gallus gallus phosphatidylcholine-sterol acyltransferase precursor lcaT SWALL:LCAT_CHICK (SWALL:P53760) (413 aa) fasta scores: E(): 6.3e-12, 27.25% id in 422 aa, and to Anas platyrhynchos lecithin cholesterol acyltransferase SWALL:Q9DDJ6 (EMBL:AF324887) (451 aa) fasta scores: E(): 1.1e-11, 26.51% id in 430 aa, and to Rattus norvegicus phosphatidylcholine-sterol acyltransferase precursor lcaT SWALL:LCAT_RAT (SWALL:P18424) (440 aa) fasta scores: E(): 1.6e-11, 27.16% id in 427 aa 23612371 2 HMMSMART RNA recognition motifs found in the sequence; first RRM motif between amino acid positions 24- 102 (3.21e-04) and the second RRM between amino acid positions 132-206 (2.21e-16) Similar to Nicotiana plumbaginifolia RNA binding protein 47 rbp47 SWALL:Q9LEB3 (EMBL:AJ292768) blast scores: E(): 1e-17, score: 93 31% id, and to Arabidopsis thaliana similarity to polyadenylate-binding protein 5 SWALL:Q9FFU0 (EMBL:AB005232) blast scores: E(): 1e-16, score: 90 30% id, and to Oryza sativa putative RNA binding protein osjnba0004b24.1 SWALL:Q9AY92 (EMBL:AC084319) blast scores: E(): 3e-16, score: 89 31% id 23612372 Pfam hit (8.3e-09) to Aa_trans (Transmembrane amino acid transporter protein): This transmembrane region is found in many amino acid transporters including UNC-47 and MTR. UNC-47 encodes a vesicular amino butyric acid (GABA) transporter, (VGAT). UNC-47 is predicted to have 10 transmembrane domains P34579 [1]. MTR is a N system amino acid transporter system protein involved in methyltryptophan resistance P38680. Other members of this family include proline transporters and amino acid permeases Similar to Rattus norvegicus amino acid transporter system n2 SWALL:Q91XR7 (EMBL:AF276870) blast scores: E(): 0.004, score: 45 26% id, and to Leishmania major possible amino acid transporter p883.05 SWALL:Q9BHG8 (EMBL:AL590734) (498 aa) fasta scores: E(): 1e-05, 24.14% id in 323 aa 23612374 Possible multifunctional protein; Pfam hits to SET domain (1.4e-45); Bromodomain (1.4e-05); C3H4 Zn-finger- like PHD domain (6.0e-06) 23612375 SMART hit (7.09e-09) to Cullins (between amino acid positions 702 and 853); The cullins are hydrophilic proteins involved in cell division control in yeasts [MEDLINE:00003702] and probably in various processes in the cell cycle of other organisms [MEDLINE:00000937]. Similar to Homo sapiens cullin Cul4B cul4B SWALL:Q9BY37 (EMBL:AF212995) blast scores: E(): 2e-13, score: 80 32% id, and to Schizosaccharomyces pombe cullin 3 homolog pcu3 or spac24h6.03 SWALL:CUL3_SCHPO (SWALL:Q09760) blast scores: E(): 3e-12, score: 76 30% id 23612376 Required for transport of secretory proteins from the golgi complex. catalyses the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Similar to Schizosaccharomyces pombe putative sec14 cytosolic factor spac3h8.10 SWALL:SC14_SCHPO (SWALL:Q10137) (286 aa) fasta scores: E(): 0.0027, 23.5% id in 268 aa, and to Arabidopsis thaliana similarity to phosphatidylinositol/phosphatidylcholine transfer protein SWALL:Q9FGK6 (EMBL:AB025628) (403 aa) fasta scores: E(): 1.2e- 06, 24.01% id in 229 aa, and to Lotus japonicus phosphatidylinositol transfer-like protein ii ljplp-iI SWALL:Q94FN3 (EMBL:AF366901) (550 aa) fasta scores: E(): 7.4e-05, 23.96% id in 217 aa 23612377 There is a potential exon-like GC-rich area in the genomic sequence between the exons 3 & 4 in the current gene model; however, no appropriate 5'splice acceptor and 3'splice donor site was found for prediction of a small exon in the GC-rich exon-like region 23612379 Existence of the last exon is uncertain 23612380 Similar to Schizosaccharomyces pombe DNA polymerase epsilon, catalytic subunit a cdc20 or spbc25h2.13C SWALL:DPOE_SCHPO (SWALL:P87154) (2199 aa) fasta scores: E(): 1e-48, 35.46% id in 1359 aa, and to Arabidopsis thaliana putative DNA polymerase epsilon catalytic subunit at2g27120 SWALL:Q9ZVC8 (EMBL:AC005623) (2154 aa) fasta scores: E(): 1.2e-46, 35.38% id in 1379 aa, and to Emericella nidulans DNA polymerase epsilon homolog nimP SWALL:O93845 (EMBL:AF019254) (2207 aa) fasta scores: E(): 2.6e- 46, 39.38% id in 1107 aa, and to Homo sapiens DNA polymerase epsilon catalytic subunit protein isoform c pole1 SWALL:Q9UNF3 (EMBL:AF127975) (2243 aa) fasta scores: E(): 1.5e-45, 35.5% id in 1338 aa 23612381 3 putative transmembrane domains detected by TMHMM 23612382 There are 4 putative WD40 repeat domains Similar to Saccharomyces cerevisiae microtubule-associated protein ytm1 ytm1 or yor272W SWALL:YTM1_YEAST (SWALL:Q12024) blast scores: E(): 4e-15, score: 84 22% id, and to Schizosaccharomyces pombe putative microtubule-associated protein c890.04c spac890.04C SWALL:Q9URY0 (EMBL:AL133498) blast scores: E(): 7e-18, score: 93 22% id 23612383 Conserved residues between codon positions 586-669 23612384 Weak pfam hit (8.7e-02) to catalytic domain of tetrahydrofolate dehydrogenase / cyclohydrolase (THF_DHG_CYH domain) and to NAD-binding THF_DHG_CYH_C domain (3.90e+00); however, other evidence are not strong enough to annotate this protein as putative P. falciparum methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5) or methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 23612386 Very strong Pfam (1.2e-76;codon 161-369) and HMMSmart hits (5.1e-54;codon 167-369) to DEAD & DEAH box helicase Similar to Schizosaccharomyces pombe putative ATP-dependent RNA helicase c1f7.02c spac1f7.02C SWALL:YAK2_SCHPO (SWALL:Q09916) (578 aa) fasta scores: E(): 2.4e-85, 48.53% id in 546 aa, and to Drosophila melanogaster probable ATP-dependent helicase pitchoune pit or cg6375 SWALL:PIT_DROME (SWALL:Q9VD51) (663 aa) fasta scores: E(): 1.7e-83, 44.87% id in 595 aa, and to Saccharomyces cerevisiae probable ATP-dependent RNA helicase has1 has1 or ymr290C SWALL:HAS1_YEAST (SWALL:Q03532) (505 aa) fasta scores: E(): 2.7e-82, 50.2% id in 490 aa, and to Arabidopsis thaliana dead box ATP dependent helicase protein f6h11.20 or at5g65900 or k14b20.7 SWALL:O49530 (EMBL:AL021684) (633 aa) fasta scores: E(): 1.8e-76, 42.13% id in 591 aa 23612387 Contains putative TPR repeat units 23612388 The gene structure is not like rifins but the amino acid sequence is highly similar to rifins Similar to Plasmodium falciparum rifin pfb1040W SWALL:O96293 (EMBL:AE001433) (345 aa) fasta scores: E(): 3.5e-14, 53.71% id in 121 aa 23612389 Similar to Plasmodium falciparum variant surface antigen rifin 3 rif3 SWALL:Q9U737 (EMBL:AF161311) (350 aa) fasta scores: E(): 2.8e- 69, 61.75% id in 353 aa 23612390 Similar to Plasmodium falciparum VaR, mal1p4.01 vaR SWALL:Q9NFB6 (EMBL:AL031747) (2163 aa) fasta scores: E(): 2e-125, 80.71% id in 446 aa 23612391 Similar to Plasmodium falciparum RifiN, mal1p4.04 rifiN SWALL:Q9NFB3 (EMBL:AL031747) (372 aa) fasta scores: E(): 5e-84, 68.43% id in 377 aa 23612392 Does not produce Pfam hit to PFEMP domain (pfam:PF03011), found in Pfemp1 protein family Similar to Plasmodium falciparum var-like protein, Mal1p4.03 mal1p4.03 SWALL:Q9NFB4 (EMBL:AL031747) (1327 aa) fasta scores: E(): 0, 82.61% id in 1329 aa 23612393 Similar to Plasmodium falciparum rifin pfb1010W SWALL:O96289 (EMBL:AE001432) (368 aa) fasta scores: E(): 4.3e-67, 56.15% id in 374 aa 23612394 Similar to Plasmodium falciparum variant-specific surface protein var-3 SWALL:Q26032 (EMBL:L40609) (3006 aa) fasta scores: E(): 5.2e- 181, 43.04% id in 3157 aa 23612395 Similar to Plasmodium falciparum fcr3 csa ligand vaR SWALL:Q9U5M2 (EMBL:AJ133811) (3542 aa) fasta scores: E(): 8.9e-33, 41.75% id in 273 aa 23612415 Similar to Plasmodium falciparum variant-specific surface protein var-3 SWALL:Q26032 (EMBL:L40609) (3006 aa) fasta scores: E(): 8e-125, 38.49% id in 3673 aa 23612416 Similar to Plasmodium falciparum RifiN, mal1p4.04 rifiN SWALL:Q9NFB3 (EMBL:AL031747) (372 aa) fasta scores: E(): 6.3e-63, 53.66% id in 382 aa 23612417 Similar to Plasmodium falciparum Pfc0030c, mal3p8.5 protein pfc0030c, mal3p8.5 SWALL:O97326 (EMBL:AL034560) (359 aa) fasta scores: E(): 5.4e-85, 73.25% id in 359 aa, and to Plasmodium falciparum rifin, Mal1p4.06 mal1p4.06 SWALL:Q9NFB2 (EMBL:AL031747) (359 aa) fasta scores: E(): 1.1e-75, 66.01% id in 359 aa 23612418 Similar to Plasmodium falciparum conserved hypothetical membrane protein pfc1090w, mal3p7.49 SWALL:O97308 (EMBL:AL034559) (309 aa) fasta scores: E(): 7.2e-78, 99.61% id in 257 aa, and to Plasmodium falciparum predicted integral membrane protein pfb0995W SWALL:Q9TY93 (EMBL:AE001431) (257 aa) fasta scores: E(): 2.3e-77, 99.22% id in 257 aa 23612419 Similar to Plasmodium falciparum pfc1085c protein pfc1085c or pfb0990C SWALL:O97474 (EMBL:AL034559) (230 aa) fasta scores: E(): 6.4e-80, 99.56% id in 230 aa 23612420 Similar to Plasmodium falciparum hypothetical membrane protein, pfc1080c pfc1080c, mal3p7.47 SWALL:O97307 (EMBL:AL034559) (231 aa) fasta scores: E(): 3.5e-46, 76.19% id in 189 aa 23612421 Similar to Plasmodium falciparum pfc1075w protein pfc1075w or pfb0980W SWALL:O97462 (EMBL:AL034559) (282 aa) fasta scores: E(): 2.7e-97, 99.64% id in 282 aa 23612422 Similar to Plasmodium falciparum rifin pfb1050W SWALL:O96295 (EMBL:AE001434) (327 aa) fasta scores: E(): 7.5e-43, 46.76% id in 340 aa 23612425 Similar to Plasmodium falciparum ring-infected erythrocyte surface antigen precursor resA SWALL:RESA_PLAFF (SWALL:P13830) (1073 aa) fasta scores: E(): 5.5e-10, 22.84% id in 534 aa 23612426 Similarity to lysophospholipases are not convincing but low similarity to several lysophospholipases Similar to Arabidopsis thaliana lysophospholipase-like protein f2g14_100 SWALL:Q9LFQ7 (EMBL:AL391146) (327 aa) fasta scores: E(): 0.063, 23.01% id in 252 aa, and to Clostridium acetobutylicum lysophospholipase l2 pldb, hydrolase of alpha/beta superfamily cac2246 SWALL:Q97GW9 (EMBL:AE007724) (363 aa) fasta scores: E(): 0.85, 32.45% id in 114 aa, and to Arabidopsis thaliana putative phospholipase at2g39400 SWALL:O80627 (EMBL:AC004218) (317 aa) fasta scores: E(): 0.87, 21.06% id in 318 aa, and to Anabaena sp. lysophospholipase alr0851 SWALL:Q8YYJ7 (EMBL:AP003583) (281 aa) fasta scores: E(): 1.6, 23.31% id in 193 aa 23612427 Not identical to submited starp antigen sequence from T9/96 strain Similar to Plasmodium falciparum starp antigen SWALL:Q26021 (EMBL:Z26314) (604 aa) fasta scores: E(): 1e-133, 98.01% id in 604 aa 23612430 No GO terms added because this is a small 5' fragment of chitinase precursor gene, and thus would not be functional; could be a pseudo gene Similar to Plasmodium berghei chitinase precursor cht1 SWALL:Q966Z6 (EMBL:AJ305256) (648 aa) fasta scores: E(): 0.0002, 36.14% id in 83 aa 23612433 Similar to Mus musculus hypothetical protein CGI-128 homolog SWALL:CGC8_MOUSE (SWALL:Q9D187) (163 aa) fasta scores: E(): 1.3e-20, 43.37% id in 166 aa 23612437 Weak hit to DEAD-like helicase domain (8.24e-03) Similar to Plasmodium falciparum erythrocyte membrane-associated antigen SWALL:Q9GVB0 (EMBL:X53022) (252 aa) fasta scores: E(): 1.1e-74, 98.42% id in 254 aa 23612451 Similar to Synechocystis sp. peptide chain release factor 2 prfb or sll1865 SWALL:RF2_SYNY3 (SWALL:P74476) (372 aa) fasta scores: E(): 1.3e-13, 34.85% id in 307 aa 23612455 Annotation is based on FASTA and BLASTP evidence Similar to Homo sapiens origin recognition complex subunit 2 orc2l or orc2 SWALL:ORC2_HUMAN (SWALL:Q13416) blast scores: E(): 2e-17, score: 93 26% id, and to Schizosaccharomyces pombe origin recognition complex subunit 2 orc2 or orp2 or spbc685.09 SWALL:ORC2_SCHPO (SWALL:Q09142) blast scores: E(): 4e-17, score: 92 23% id 23612456 Similar to Mus musculus DNA replication licensing factor mcm7 mcm7 or mcmd7 or cdc47 SWALL:MCM7_MOUSE (SWALL:Q61881) (719 aa) fasta scores: E(): 1.5e-70, 38.82% id in 783 aa 23612462 Similar to Saccharomyces cerevisiae hypothetical 29.7 kDa protein in rsp5-lcp5 intergenic region yer126c or sygp-orf47 SWALL:YEV6_YEAST (SWALL:P40078) (261 aa) fasta scores: E(): 8.6e-50, 55.93% id in 261 aa, and to Mus musculus 5730427n09riK protein 5730427n09riK SWALL:Q9CR47 (EMBL:AK014275) (260 aa) fasta scores: E(): 4.2e-59, 61.92% id in 260 aa, and to Homo sapiens hypothetical protein tinp1 SWALL:O95478 (EMBL:AJ012409) (260 aa) fasta scores: E(): 4.9e-59, 61.92% id in 260 aa 23612464 Similar to Brassica napus DNA-directed RNA polymerase ii 8.2 kDa polypeptide SWALL:RPBX_BRANA (SWALL:Q39290) (71 aa) fasta scores: E(): 1.5e-15, 59.7% id in 67 aa, and to Schizosaccharomyces pombe DNA-directed RNA polymerases i, ii, and iii 8.3 kDa polypeptide rpb10 or spac1b3.12C SWALL:RPBX_SCHPO (SWALL:O13877) (71 aa) fasta scores: E(): 1.7e-15, 60.31% id in 63 aa 23612466 Similar to Sulfolobus solfataricus O-sialoglycoprotein endopeptidase sso0433 SWALL:Q97ZY9 (EMBL:AE006676) (223 aa) fasta scores: E(): 4.5e-07, 30.35% id in 224 aa, and to Pyrococcus furiosus O-sialoglycoprotein endopeptidase pf0473 SWALL:AAL80597 (EMBL:AE010170) (226 aa) fasta scores: E(): 3.4e-09, 28.99% id in 238 aa 23612467 Similar to Plasmodium falciparum heat shock protein 86 hsp86 SWALL:Q25882 (EMBL:L34027) (745 aa) fasta scores: E(): 0, 100% id in 745 aa 23612468 Similar to Plasmodium falciparum strain dd2 heat shock protein 86 o1 SWALL:O15793 (EMBL:AF030694) (776 aa) fasta scores: E(): 8e-187, 95.17% id in 766 aa 23612469 Similar to Plasmodium falciparum strain dd2 heat shock protein 86 o2 SWALL:O15795 (EMBL:AF030694) (205 aa) fasta scores: E(): 1.8e-71, 100% id in 205 aa 23612470 Similar to Plasmodium falciparum Cg8 cg8 SWALL:O15796 (EMBL:AF030694) (207 aa) fasta scores: E(): 8.2e-79, 98.53% id in 205 aa 23612471 Similar to Plasmodium falciparum Cg4 cg4 SWALL:O15797 (EMBL:AF030694) (855 aa) fasta scores: E(): 0, 100% id in 854 aa, and to Strongylocentrotus franciscanus 97 kDa heat shock protein hsp110 SWALL:HS97_STRFN (SWALL:Q94738) (886 aa) fasta scores: E(): 4e-21, 25.89% id in 919 aa 23612472 Similar to Plasmodium falciparum Cg3 cg3 SWALL:O15798 (EMBL:AF030694) (328 aa) fasta scores: E(): 1.6e-119, 100% id in 310 aa, and to Schizosaccharomyces pombe hypothetical sco1/2-like protein spbc119.06 SWALL:SCOH_SCHPO (SWALL:O42899) (263 aa) fasta scores: E(): 7.9e-23, 38.33% id in 240 aa, and to Homo sapiens sco1 protein homolog, mitochondrial precursor sco1 or scod1 SWALL:SCO1_HUMAN (SWALL:O75880) (301 aa) fasta scores: E(): 2.3e-21, 39.74% id in 239 aa 23612473 Similar to Plasmodium falciparum putative chloroquine resistance transporter crT SWALL:Q9N623 (EMBL:AF233068) (424 aa) fasta scores: E(): 5.9e-159, 97.09% id in 413 aa 23612474 Similar to Plasmodium falciparum cg1 protein SWALL:Q9NG57 (EMBL:AF260819) (939 aa) fasta scores: E(): 0, 99.57% id in 939 aa 23612475 Similar to Plasmodium falciparum Cg6 cg6 SWALL:O15800 (EMBL:AF030694) (272 aa) fasta scores: E(): 1.2e-99, 99.26% id in 272 aa 23612476 Similar to Plasmodium falciparum Cg2 cg2 SWALL:O15791 (EMBL:AF030692) (2708 aa) fasta scores: E(): 0, 97.73% id in 2738 aa 23612477 Similar to Plasmodium falciparum Cg7 cg7 SWALL:O15802 (EMBL:AF030694) (1281 aa) fasta scores: E(): 0, 99.68% id in 1281 aa 23612480 Similar to Pyrococcus furiosus lysophospholipase pf0480 SWALL:AAL80604 (EMBL:AE010171) (257 aa) fasta scores: E(): 0.00061, 25.28% id in 261 aa, and to Pyrococcus abyssi lysophospholipase pab1050 SWALL:Q9UYB4 (EMBL:AJ248288) (259 aa) fasta scores: E(): 0.029, 23.95% id in 288 aa 23612486 Alternative start site possible 23612487 Alternative start site possible 23612488 Similar to Saccharomyces cerevisiae 60S ribosomal protein l34-a rpl34a or yer056bC SWALL:R34A_YEAST (SWALL:P87262) (121 aa) fasta scores: E(): 4.3e-19, 56.19% id in 121 aa 23612491 Similar to Mycoplasma pneumoniae 50s ribosomal protein l1 rpla or mpn220 or mp611 SWALL:RL1_MYCPN (SWALL:P78035) (226 aa) fasta scores: E(): 6.9e-09, 36.71% id in 128 aa, and to Bacillus subtilis 50s ribosomal protein l1 rplA SWALL:RL1_BACSU (SWALL:Q06797) (231 aa) fasta scores: E(): 2e-08, 31.84% id in 157 aa 23612492 Similar to Plasmodium falciparum putative cell division cycle ATPase SWALL:CDAT_PLAFA (SWALL:P46468) (709 aa) fasta scores: E(): 0, 99.85% id in 709 aa, and to Saccharomyces cerevisiae cell division control protein 48 cdc48 or ydl126C SWALL:CC48_YEAST (SWALL:P25694) (835 aa) fasta scores: E(): 1.8e-58, 40.24% id in 912 aa 23612496 Similar to Mus musculus sin3 associated polypeptide p18 sap18 SWALL:SP18_MOUSE (SWALL:O55128) blast scores: E(): 1e-11, score: 73 35% id, and to Homo sapiens sin3 associated polypeptide p18 sap18 SWALL:SP18_HUMAN (SWALL:O00422) blast scores: E(): 1e-11, score: 73 36% id, and to Plasmodium falciparum strain dd2 heat shock protein 86 o1 SWALL:O15793 (EMBL:AF030694) (776 aa) fasta scores: E(): 2.2e-10, 25.11% id in 657 aa, and to Nicotiana tabacum KeD keD SWALL:Q9LW95 (EMBL:AB009883) (513 aa) fasta scores: E(): 3.4e-10, 26.03% id in 461 aa 23612497 Similar to Drosophila melanogaster regulator of chromosome condensation bj1 or cg10480 SWALL:RCC1_DROME (SWALL:P25171) (547 aa) fasta scores: E(): 2.2e-11, 25% id in 592 aa, and to Xenopus laevis regulator of chromosome condensation rcc1 SWALL:RCC1_XENLA (SWALL:P25183) (424 aa) fasta scores: E(): 8.2e-11, 24.56% id in 399 aa 23612498 Although it is similar to N-terminus of human transcritption factor 1 mitochondrial precursor, this protein is of much smaller in length; thus, it may not not function as a functional transcription factor Similar to SWALL:MTT1_HUMAN (SWALL:) (246 aa) fasta scores: E(): 10, 36% id in 50 aa 23612499 Similar to Plasmodium falciparum variant-specific surface protein var-7 SWALL:Q26034 (EMBL:L42636) (2182 aa) fasta scores: E(): 4.3e-120, 49.54% id in 2329 aa 36329003781 pseudoRIF gene, putative 23612500 Similar to Plasmodium falciparum var, mal4p2.58 mal4p2.58, vaR SWALL:Q9U0G5 (EMBL:AL035475) (2277 aa) fasta scores: E(): 0, 45.99% id in 2411 aa 36329003783 pseudo RIF gene 23612501 Similar to Plasmodium falciparum var, mal4p2.58 mal4p2.58, vaR SWALL:Q9U0G5 (EMBL:AL035475) (2277 aa) fasta scores: E(): 4.4e-123, 48.9% id in 2417 aa 23612502 Similar to Plasmodium falciparum erythrocyte membrane protein 1 var1 SWALL:Q95W83 (EMBL:AF366567) (2527 aa) fasta scores: E(): 6.2e-134, 42.42% id in 1702 aa 36329003786 Pseudo-RIF gene 23612503 Similar to Plasmodium falciparum erythrocyte membrane protein 1 fcr3s1.2-var1 SWALL:O60991 (EMBL:AF003473) (2228 aa) fasta scores: E(): 7.8e-175, 48.73% id in 2331 aa 23612504 Similar to Plasmodium falciparum variant-specific surface protein var-7 SWALL:Q26034 (EMBL:L42636) (2182 aa) fasta scores: E(): 5.2e-161, 46% id in 2363 aa 23612505 Similar to Plasmodium falciparum pfemp1 pfb1055C SWALL:O96296 (EMBL:AE001434) (2197 aa) fasta scores: E(): 0, 52.23% id in 2330 aa 23612506 Similar to Plasmodium falciparum variant surface antigen rifin 1 rif1 SWALL:Q9U6Q4 (EMBL:AF180393) (337 aa) fasta scores: E(): 1.3e-59, 55.46% id in 348 aa 23612507 Similar to Plasmodium falciparum hypothetical membrane protein, pfc1080c pfc1080c, mal3p7.47 SWALL:O97307 (EMBL:AL034559) (231 aa) fasta scores: E(): 2.2e-51, 66.23% id in 231 aa 23612508 Similar to Plasmodium falciparum pfc1075w protein pfc1075w or pfb0980W SWALL:O97462 (EMBL:AL034559) (282 aa) fasta scores: E(): 2.9e-50, 80.88% id in 204 aa 36329003793 pseudo-VAR fragment 36329003794 pseudo-VAR fragment 36329003795 pseudo-VAR fragment 36329003796 pseudo-VAR fragment 23612512 Moderate similarity to Synechocystis sp; hypothetical protein Sll0447 (SWALL:P74681 (EMBL:D90917)) Similar to Synechocystis sp. hypothetical protein Sll0447 sll0447 SWALL:P74681 (EMBL:D90917) (268 aa) fasta scores: E(): 2.1, 24.64% id in 211 aa 23612515 Similar to Toxoplasma gondii histone h2b variant 1 SWALL:Q95VT2 (EMBL:AF406555) (123 aa) fasta scores: E(): 2.1e-40, 89.43% id in 123 aa 23612518 Conserved residues in the first 300 amino acids in the N-terminus with other conserved hypothetical proteins from Arabidopsis, Oryza sativa, human Similar to Arabidopsis thaliana emb|cab87904.1 at5g41060 SWALL:AAL85057 (EMBL:AB010072) (410 aa) fasta scores: E(): 1e-26, 36.31% id in 369 aa, and to Arabidopsis thaliana hypothetical 53.1 kDa protein t21j18_30 SWALL:Q9M306 (EMBL:AL132963) (470 aa) fasta scores: E(): 5.4e-25, 39.79% id in 289 aa, and to Oryza sativa similar to arabidopsis thaliana DNA chromosome 4 SWALL:Q9SDJ3 (EMBL:AP000815) (414 aa) fasta scores: E(): 2.4e-20, 34.78% id in 322 aa, and to Homo sapiens Dj50o24.4 dj50o24.4 SWALL:Q9NUE0 (EMBL:AL034380) (396 aa) fasta scores: E(): 2.5e-19, 34.48% id in 290 aa 23612519 Similar to Phytophthora infestans calmodulin cmd1 or calpI SWALL:CALM_PHYIN (SWALL:P27165) (148 aa) fasta scores: E(): 0.12, 29.5% id in 122 aa, and to Dictyostelium discoideum calmodulin cama or calA SWALL:CALM_DICDI (SWALL:P02599) (151 aa) fasta scores: E(): 0.17, 31.14% id in 122 aa, and to Pneumocystis carinii calmodulin SWALL:CALM_PNECA (SWALL:P41041) (151 aa) fasta scores: E(): 0.19, 27.69% id in 130 aa 23612520 Similar to Caenorhabditis elegans putative transcription elongation factor s-ii t24h10.1 SWALL:TFS2_CAEEL (SWALL:P52652) (308 aa) fasta scores: E(): 3.4e-10, 38.54% id in 179 aa, and to Arabidopsis thaliana putative elongation factor at2g38560 SWALL:Q8VXZ6 (EMBL:AY074322) (378 aa) fasta scores: E(): 7.3e-13, 26.41% id in 371 aa, and to Drosophila melanogaster transcription elongation factor s-ii tfiis or dmsii or cg3710 SWALL:TFS2_DROME (SWALL:P20232) (313 aa) fasta scores: E(): 3.5e-09, 27.22% id in 360 aa 23612522 Similar to Schizosaccharomyces pombe 4-nitrophenylphosphatase pho2 or spbc15d4.15 SWALL:PNPP_SCHPO (SWALL:Q00472) (298 aa) fasta scores: E(): 7.3e-32, 36.67% id in 289 aa, and to Chlamydomonas reinhardtii phosphoglycolate phosphatase precursor pgp1 SWALL:Q948T5 (EMBL:AB052169) (330 aa) fasta scores: E(): 2.2e-45, 46.15% id in 286 aa, and to Arabidopsis thaliana 4-nitrophenylphosphatase-like protein SWALL:Q9FIK4 (EMBL:AB016886) (311 aa) fasta scores: E(): 1.1e-42, 41.86% id in 289 aa 23612523 Similar to Drosophila melanogaster Cg4546 protein cg4546 SWALL:Q9VF23 (EMBL:AE003710) (458 aa) fasta scores: E(): 0.0022, 31.86% id in 91 aa 23612525 Similar to Emericella nidulans calcium/calmodulin-dependent protein kinase cmkA SWALL:KCC1_EMENI (SWALL:Q00771) (414 aa) fasta scores: E(): 6e-11, 27.02% id in 296 aa, and to Nicotiana tabacum calcium/calmodulin dependent protein kinase ccamk or ccamk-1 SWALL:Q9S792 (EMBL:U38446) (517 aa) fasta scores: E(): 4.1e-11, 30.07% id in 256 aa 23612526 Although moderately similar to Carsonella ruddii; ATP synthase gamma subunit, this pprotein does not produce any pfam hit to ATP synthases Similar to Carsonella ruddii ATP synthase gamma subunit atpG SWALL:Q93UB9 (EMBL:AF267206) (252 aa) fasta scores: E(): 3.4, 29.19% id in 161 aa 23612527 Similar to Arabidopsis thaliana ATP synthase epsilon chain, mitochondrial at1g51650 or f19c24.25 SWALL:ATP5_ARATH (SWALL:Q96253) (69 aa) fasta scores: E(): 0.00035, 42.85% id in 49 aa, and to Zea mays ATP synthase epsilon chain, mitochondrial SWALL:ATP5_MAIZE (SWALL:Q41898) (70 aa) fasta scores: E(): 0.013, 37.5% id in 48 aa, and to Ipomoea batatas ATP synthase epsilon chain, mitochondrial SWALL:ATP5_IPOBA (SWALL:Q06450) blast scores: E(): 3e-06, score: 50 42% id 23612528 Similar to Caulobacter crescentus elongation factor tu family protein cc0741 SWALL:Q9AA65 (EMBL:AE005749) (610 aa) fasta scores: E(): 2.1e-45, 36.88% id in 667 aa, and to Agrobacterium tumefaciens GTP-binding tyrosin phosphorylated protein typa or atu2663 or agr_c_4827 SWALL:AAL43644 (EMBL:AE009213) (606 aa) fasta scores: E(): 4.9e-42, 37.82% id in 661 aa, and to Haemophilus influenzae GTP-binding protein typa/bipa homolog typa or hi0864 SWALL:TYPA_HAEIN (SWALL:P44910) (616 aa) fasta scores: E(): 6.6e-41, 37.63% id in 667 aa 23612531 Similar to Plasmodium falciparum putative zinc transporter SWALL:Q9NFG4 (EMBL:AJ290934) (74 aa) fasta scores: E(): 4.9e-21, 100% id in 74 aa, and to Rattus norvegicus zinc transporter 2 slc30a2 or znt2 SWALL:ZNT2_RAT (SWALL:Q62941) (359 aa) fasta scores: E(): 2.1e-17, 35.29% id in 170 aa, and to Arabidopsis thaliana zinc transporter zat SWALL:Q9ZT63 (EMBL:AF072858) (398 aa) fasta scores: E(): 1.1e-15, 27.09% id in 524 aa 23612533 Partial similarity to Plasmodium falciparum Aarp1 protein; high similarity in the repeat region of the protein Similar to Plasmodium falciparum Aarp1 protein aarp1 SWALL:Q94648 (EMBL:Y08926) (3844 aa) fasta scores: E(): 4.7e-16, 25.6% id in 1078 aa 23612536 Similarity to Bacillus subtilis DNA-directed RNA polymerase delta subunit is not strong enough to call this protein a homologue of rpoE Similar to Bacillus subtilis DNA-directed RNA polymerase delta subunit rpoE SWALL:RPOE_BACSU (SWALL:P12464) (173 aa) fasta scores: E(): 2, 35.29% id in 68 aa 23612537 Partial similarity to Clostridium acetobutylicum glycosyltransferase domain containing protein cac2176 but pfam search does not produce significant hit to glycosyltransferase domain Similar to Clostridium acetobutylicum glycosyltransferase domain containing protein cac2176 SWALL:Q97H37 (EMBL:AE007717) (937 aa) fasta scores: E(): 0.0062, 24.85% id in 346 aa 23612538 Similar to Borrelia burgdorferi probable cysteine desulfurase csd or bb0084 SWALL:CSD_BORBU (SWALL:O51111) (422 aa) fasta scores: E(): 7e-29, 30.96% id in 423 aa, and to Streptomyces coelicolor probable cysteine desulfurase csd or sco1921 or scc22.03C SWALL:CSD_STRCO (SWALL:Q9XAD5) (418 aa) fasta scores: E(): 1.3e-26, 26.01% id in 469 aa 23612540 Similar to Schizosaccharomyces pombe eukaryotic translation initiation factor 3 39 kDa subunit tif34 or sum1 or spac4d7.05 SWALL:IF32_SCHPO (SWALL:P79083) (328 aa) fasta scores: E(): 1.9e-37, 35.88% id in 340 aa, and to Homo sapiens eukaryotic translation initiation factor 3 subunit 2 eif3s2 or trip1 SWALL:IF32_HUMAN (SWALL:Q13347) (325 aa) fasta scores: E(): 2.5e-35, 31.13% id in 334 aa 23612541 Similar to Sulfolobus solfataricus allantoin permease sso2042 SWALL:Q97WS4 (EMBL:AE006811) (492 aa) fasta scores: E(): 0.17, 27.32% id in 194 aa, and to Encephalitozoon cuniculi nicotinic acid transporter ecu08_0640 SWALL:CAD26369 (EMBL:AL590448) (301 aa) fasta scores: E(): 0.36, 20.7% id in 285 aa, and to Arabidopsis thaliana putative purine permease pup2 SWALL:Q94GB1 (EMBL:AF078532) (358 aa) fasta scores: E(): 0.71, 26.14% id in 218 aa 23612544 Hit to PfaDd2|0759c3|1999.12.28|EST|UFla 120..15 score: 210 percent id: 100.00 23612545 Similar to Mus musculus transcription initiation factor iie, alpha subunit gtf2e1 SWALL:T2EA_MOUSE (SWALL:Q9D0D5) (440 aa) fasta scores: E(): 0.00027, 26.31% id in 152 aa, and to Homo sapiens transcription initiation factor iie, alpha subunit gtf2e1 or tf2e1 SWALL:T2EA_HUMAN (SWALL:P29083) (439 aa) fasta scores: E(): 0.00039, 26.31% id in 152 aa, and to Saccharomyces cerevisiae transcription initiation factor iie, alpha subunit tfa1 or ykl028W SWALL:T2EA_YEAST (SWALL:P36100) (482 aa) fasta scores: E(): 0.0033, 18.52% id in 394 aa 23612546 Similar to Drosophila melanogaster probable queuine trna-ribosyltransferase cg4947 SWALL:TGT_DROME (SWALL:Q9VPY8) (427 aa) fasta scores: E(): 5.4e-35, 29.84% id in 506 aa, and to Drosophila melanogaster probable queuine trna-ribosyltransferase cg4947 SWALL:TGT_DROME (SWALL:Q9VPY8) blast scores: E(): 1e-54, score: 543 41% id, and to Schizosaccharomyces pombe probable queuine trna-ribosyltransferase spac1687.19C SWALL:O94460 (EMBL:AL035064) blast scores: E(): 2e-52, score: 525 43% id 23612547 Similar to Toxoplasma gondii calmodulin-domain protein kinase 1 cdpk1 SWALL:Q9BJF5 (EMBL:AF333958) (507 aa) fasta scores: E(): 7.5e-122, 74.36% id in 472 aa, and to Eimeria tenella calmodulin-domain protein kinase SWALL:Q24929 (EMBL:Z71757) (487 aa) fasta scores: E(): 1.6e-118, 72.88% id in 472 aa 23612549 Similar to Helianthus annuus seryl-trna synthetase SWALL:SYS_HELAN (SWALL:O81983) (438 aa) fasta scores: E(): 2.8e-31, 40.55% id in 540 aa, and to Arabidopsis thaliana seryl-trna synthetase at5g27470 or f21a20_180 SWALL:SYS_ARATH (SWALL:Q39230) (451 aa) fasta scores: E(): 1.8e-30, 37.73% id in 538 aa 23612551 Similarity to several thioredoxins of prokaryotic origin but this protein is much longer in size (449 residues) as compared to thioredoxins (length ~110 amino acids) that maps to amino acid positions between 220 and 310 in this hypothetical protein Similar to Thiobacillus ferrooxidans thioredoxin trxA SWALL:THIO_THIFE (SWALL:P52233) (108 aa) fasta scores: E(): 0.0061, 32.55% id in 86 aa, and to Rickettsia prowazekii thioredoxin trxa or rp002 SWALL:THIO_RICPR (SWALL:Q9ZEE0) (105 aa) fasta scores: E(): 0.043, 27.35% id in 106 aa 23612552 It could be composed of 2 separate hypothetical proteins: first 8 exons forming one protein and the last 3 exons forming the second hypothetical protein; low similarity to P. falciparum reticulocyte-binding protein and dynein heavy chain Similar to Homo sapiens axonemal dynein heavy chain dnah5 SWALL:AAK92217 (EMBL:AY045575) (4624 aa) fasta scores: E(): 8.4e-18, 20.64% id in 1511 aa, and to Plasmodium falciparum reticulocyte binding protein 2 homolog b rbP SWALL:Q9BK45 (EMBL:AF312917) blast scores: E(): 3e-08, score: 62 20% id 23612553 Similar to Plasmodium falciparum exported serine/threonine protein kinase fesT SWALL:Q94658 (EMBL:U40232) (2510 aa) fasta scores: E(): 0, 96.78% id in 2522 aa 23612554 Similar to Plasmodium berghei cysteine repeat modular protein 2 pbcrm2 SWALL:Q8WRD1 (EMBL:AF449197) (2534 aa) fasta scores: E(): 0, 65.54% id in 2551 aa 23612555 Similar to Acanthamoeba castellanii mitochondrial ribosomal protein s8 rps8 SWALL:RT08_ACACA (SWALL:P46757) (127 aa) fasta scores: E(): 8.7e-09, 39.39% id in 99 aa 23612556 Similar to Homo sapiens prefoldin subunit 3 vbp1 or pfdn3 SWALL:PFD3_HUMAN (SWALL:Q15765) (185 aa) fasta scores: E(): 4.1e-15, 36.25% id in 160 aa, and to Drosophila melanogaster probable prefoldin subunit 3 cg6719 SWALL:PFD3_DROME (SWALL:Q9VGP6) (185 aa) fasta scores: E(): 2.5e-14, 35.29% id in 170 aa 23612558 Hit to Pfa3D7|3929|2000.12.28|EST|UTokyo 497..290 score: 412 percent id: 100.00 23612562 Similar to Plasmodium falciparum predicted integral membrane protein pfb0785C SWALL:O96250 (EMBL:AE001418) (307 aa) fasta scores: E(): 0.31, 24.08% id in 191 aa 36329003851 Alternative gene model possible Similar to SWALL:STK2_HUMAN (SWALL:) (841 aa) fasta scores: E(): 1.3e-36, 40.06% id in 292 aa, and to Leishmania major nek-related serine/threonine-protein kinase nek1 p1408.02 SWALL:Q9N9C3 (EMBL:AL358652) (555 aa) fasta scores: E(): 1.1e-33, 38.68% id in 274 aa, and to Mus musculus serine/threonine-protein kinase Nek1 nek1 SWALL:NEK1_MOUSE (SWALL:P51954) (774 aa) fasta scores: E(): 1.4e-33, 37.87% id in 301 aa 23612565 Similar to Homo sapiens Dj234p15.3 dj234p15.3 SWALL:Q9UGC2 (EMBL:AL080250) (359 aa) fasta scores: E(): 7.4e-22, 34.35% id in 326 aa, and to Mus musculus similar to hypothetical protein flj10856 SWALL:Q8VEK0 (EMBL:BC018367) (364 aa) fasta scores: E(): 6.9e-18, 35.07% id in 325 aa 23612566 Hit to PfaDd2|1432c3|1999.12.28|EST|UFla 138..403 score: 519 percent id: 100.00 Similar to Arabidopsis thaliana 60S ribosomal protein l11a rpl11a or rpl16a or at2g42740 or f7d19.26 SWALL:R111_ARATH (SWALL:P42795) (182 aa) fasta scores: E(): 1.1e-48, 71.34% id in 171 aa, and to Medicago sativa 60S ribosomal protein l11 rpl11 or rpl5 SWALL:RL11_MEDSA (SWALL:P46287) (181 aa) fasta scores: E(): 6.9e-49, 72.51% id in 171 aa 23612567 Similar to Homo sapiens 40s ribosomal protein s10 rps10 SWALL:RS10_HUMAN (SWALL:P46783) (165 aa) fasta scores: E(): 8.8e-20, 51.93% id in 129 aa, and to Lumbricus rubellus 40s ribosomal protein s10 rps10 SWALL:RS10_LUMRU (SWALL:O77302) (156 aa) fasta scores: E(): 2.9e-20, 49.6% id in 125 aa 23612569 Existence of an intron (210 bp) possible 23612570 Similar to Homo sapiens 3'-5' exoribonuclease Csl4 homolog csl4 SWALL:AAH22067 (EMBL:AF151866) (195 aa) fasta scores: E(): 1.7e-12, 32.96% id in 179 aa, and to Homo sapiens 3'-5' exoribonuclease Csl4 homolog csl4 SWALL:CSL4_HUMAN (SWALL:Q9Y3B2) (195 aa) fasta scores: E(): 1.7e-12, 32.96% id in 179 aa, and to Mus musculus 2610104c07riK protein 2610104c07riK SWALL:Q9DAA6 (EMBL:AK006018) (195 aa) fasta scores: E(): 1.3e-12, 33.52% id in 179 aa 23612571 Similar to Saccharomyces cerevisiae hypothetical 36.4 kDa protein in pop2-hol1 intergenic region ynr054c or n3491 SWALL:YN8V_YEAST (SWALL:P53743) (316 aa) fasta scores: E(): 1.3e-09, 28.44% id in 225 aa, and to Arabidopsis thaliana hypothetical 30.6 kDa protein t5p19_160 SWALL:Q9LXY9 (EMBL:AL163972) (266 aa) fasta scores: E(): 1.4e-09, 24.32% id in 259 aa 23612574 Similar to Xenopus laevis neurula-specific ferrodoxin reductase-like protein nfrL SWALL:O42346 (EMBL:D86491) blast scores: E(): 9e-70, score: 672 30% id, and to Schizosaccharomyces pombe putative flavoprotein c26f1.14c spac26f1.14c or spac29a4.01C SWALL:YDGE_SCHPO (SWALL:Q10499) blast scores: E(): 1e-45, score: 467 26% id, and to Xenopus laevis neurula-specific ferrodoxin reductase-like protein nfrL SWALL:O42346 (EMBL:D86491) (598 aa) fasta scores: E(): 2.7e-49, 31.87% id in 549 aa 23612577 Similar to Homo sapiens hypothetical protein SWALL:O14612 (EMBL:AF001435) (152 aa) fasta scores: E(): 2, 28.26% id in 92 aa 23612579 Similar to Schizosaccharomyces pombe conserved hypothetical protein spcc830.10 SWALL:Q9UU89 (EMBL:AL109850) (188 aa) fasta scores: E(): 3.1e-18, 35.26% id in 190 aa 23612582 Similar to Plasmodium falciparum Pfc095c, mal3p8.17 protein pfc095c, mal3p8.17 SWALL:O97333 (EMBL:AL034560) (398 aa) fasta scores: E(): 0.031, 23.43% id in 239 aa 23612584 Similar to Arabidopsis thaliana dead box ATP dependent helicase protein f6h11.20 or at5g65900 or k14b20.7 SWALL:O49530 (EMBL:AL021684) (633 aa) fasta scores: E(): 4.3e-15, 30.13% id in 375 aa, and to Homo sapiens hypothetical protein flj14578 SWALL:Q96SX5 (EMBL:AK027484) (585 aa) fasta scores: E(): 3.2e-17, 37.4% id in 254 aa, and to Homo sapiens dead/dexh helicase ddx31 SWALL:Q96NY2 (EMBL:AF427339) (851 aa) fasta scores: E(): 4.2e-17, 25.1% id in 753 aa 23612585 Similar to Toxoplasma gondii P36 protein p36 SWALL:Q9GV96 (EMBL:AJ401616) (363 aa) fasta scores: E(): 3.5e-17, 32.61% id in 187 aa 23612586 One small intron possible 23612587 Similar to Mus musculus 40s ribosomal protein s5 rps5 SWALL:RS5_MOUSE (SWALL:P97461) (204 aa) fasta scores: E(): 3.5e-56, 74.86% id in 191 aa 23612590 Similar to Plasmodium falciparum hypothetical 42.2 kDa protein mal4p2.19 SWALL:Q9U0K3 (EMBL:AL035475) (344 aa) fasta scores: E(): 4.2e-07, 35.25% id in 156 aa 23612591 Similar to Drosophila melanogaster PelOta protein pelO SWALL:PELO_DROME (SWALL:P48612) (395 aa) fasta scores: E(): 7.2e-43, 35.31% id in 371 aa, and to Mus musculus pelota aa409897 or pelotA SWALL:Q91UZ2 (EMBL:AF148639) (385 aa) fasta scores: E(): 6.9e-44, 36.5% id in 389 aa 23612592 Partial domain similarity to Plasmodium yoelii yoelii p235 rhoptry protein Similar to Plasmodium yoelii yoelii p235 rhoptry protein SWALL:Q9GSC0 (EMBL:AF315285) blast scores: E(): 0.001, score: 46 25% id 23612593 One N-terminal 131 bp exon possible 23612594 Similar to Caenorhabditis elegans putative GTP-binding protein W08e3.3 w08e3.3 SWALL:YCHF_CAEEL (SWALL:P91917) (395 aa) fasta scores: E(): 2.2e-75, 52.94% id in 391 aa, and to Capsicum annuum GTP-binding protein SWALL:Q9M7P3 (EMBL:AF108896) (394 aa) fasta scores: E(): 1.4e-82, 59.69% id in 392 aa 23612595 Similar to Schizosaccharomyces pombe cell cycle control protein cwf15 cwf15 or spbc337.06C SWALL:CWFF_SCHPO (SWALL:P78794) (265 aa) fasta scores: E(): 9.4e-08, 29.19% id in 298 aa, and to Arabidopsis thaliana dbj|baa90629.1 SWALL:Q9LK52 (EMBL:AP000375) (230 aa) fasta scores: E(): 6.5e-09, 31.39% id in 293 aa 23612596 Similar to Oryza sativa P0489a01.9 protein p0489a01.9 SWALL:Q9LGT2 (EMBL:AP002484) (534 aa) fasta scores: E(): 3.1e-43, 36.11% id in 432 aa, and to Schizosaccharomyces pombe conserved hypothetical protein, similar to yeast yer082c, contains 1 wd-repeat spac959.03C SWALL:Q9P4X3 (EMBL:AL357232) (520 aa) fasta scores: E(): 1.7e-38, 31.71% id in 495 aa 23612600 Similar to Homo sapiens hypothetical protein SWALL:Q9NWX6 (EMBL:AK000553) (298 aa) fasta scores: E(): 3.9e-39, 47.11% id in 225 aa, and to Mus musculus 5730409g07riK protein 5730409g07riK SWALL:Q9CY52 (EMBL:AK010876) (298 aa) fasta scores: E(): 4.2e-38, 45.74% id in 223 aa 23612605 Similar to Mus musculus dynactin subunit p25 dctn5 or p25 or 4930427e12riK SWALL:Q9QZB9 (EMBL:AF190795) (182 aa) fasta scores: E(): 1.4e-10, 35.1% id in 188 aa, and to Neurospora crassa dynactin arp1 p25 subunit ro12 SWALL:Q9P467 (EMBL:AF264759) (189 aa) fasta scores: E(): 5.6e-11, 29.57% id in 186 aa, and to Drosophila melanogaster dynactin subunit p25 dynactin-subunit-p25 or bg:ds00929.1 or cg10846 SWALL:Q9NHE4 (EMBL:AF224265) (189 aa) fasta scores: E(): 3.8e-07, 33.75% id in 157 aa 23612607 Some domain similarity to ELAC1 proteins Similar to Homo sapiens D29 protein d29 SWALL:Q9NS99 (EMBL:AB029151) blast scores: E(): 3e-18, score: 96 27% id, and to Mus musculus similar to elac homolog 1 SWALL:Q8VEB6 (EMBL:BC019371) blast scores: E(): 4e-18, score: 95 28% id 23612608 Hit to Pfa3D7|5235|2000.12.28|EST|UTokyo 283..388 score: 210 percent id: 100.00 23612613 Similar to Arabidopsis thaliana pp2a regulatory subunit SWALL:Q9LVV2 (EMBL:AB018116) blast scores: E(): 0.015, score: 42 26% id, and to Mus musculus immunoglobulin-binding protein 1b igbp1B SWALL:IGB2_MOUSE (SWALL:Q9QZ29) blast scores: E(): 0.057, score: 40 20% id 23612614 Similar to Neisseria meningitidis 3-demethylubiquinone-9 3-methyltransferase ubig or nma0410 SWALL:UBIG_NEIMA (SWALL:Q9JWE6) (238 aa) fasta scores: E(): 2.9e-05, 26.71% id in 262 aa, and to Pasteurella multocida 3-demethylubiquinone-9 3-methyltransferase ubig or pm0840 SWALL:UBIG_PASMU (SWALL:Q9CMI6) (242 aa) fasta scores: E(): 1.4e-06, 26.88% id in 212 aa 23612615 Contains DNAJ domain Similar to Mus musculus 1810055d05riK protein 1810055d05riK SWALL:Q9CQV7 (EMBL:AK012051) blast scores: E(): 5e-14, score: 78 62% id, and to Homo sapiens DNAJ domain-containing protein McJ mcJ SWALL:Q9Y5T4 (EMBL:AF126743) blast scores: E(): 2e-12, score: 72 55% id 23612616 Weak similarity to Sulfolobus tokodaii putative purine ntpase Similar to Sulfolobus tokodaii DNA double-strand break repair rad50 ATPase rad50 or st2108 SWALL:Q96YR5 (EMBL:AP000988) (882 aa) fasta scores: E(): 0.29, 28.61% id in 304 aa 23612617 Similar to Plasmodium falciparum putative serine/threonine protein kinase pfc0385c, mal3p3.12 SWALL:O77328 (EMBL:Z98547) blast scores: E(): 5e-19, score: 99 24% id, and to Plasmodium falciparum hypothetical 214.7 kDa protein pfb0540W SWALL:O96201 (EMBL:AE001401) (1844 aa) fasta scores: E(): 3e-41, 26.92% id in 2039 aa 23612618 This hypothetical gene could be a part of the large hypothetical protein MAL1P1.134 23612620 kelch domain containing proteins could have diverse functions. Scruin is an actin cross-linking protein; galactose oxidase catalyses the oxidation of the hydroxyl group at the C6 position in D-galactose; neuraminidase hydrolyses sialic acid residues from glycoproteins; and kelch may have a cytoskeletal function, as it is localised to the actin-rich ring canals that connect the 15 nurse cells to the developing oocyte in Drosophila [MEDLINE:96019249]. Nevertheless, based on the location of the kelch pattern in the catalytic unit in galactose oxidase, functionally important residues have been predicted in glyoxal oxidase [MEDLINE:94172626]; GO annotation is based on known function of Kelch-like protein in human Similar to Homo sapiens kelch-like protein 1 klhl1 SWALL:Q96RF4 (EMBL:AF393973) (582 aa) fasta scores: E(): 1.2e-14, 27.15% id in 232 aa, and to Fugu rubripes kelch protein kelch1 SWALL:Q9W6R2 (EMBL:AF146687) (518 aa) fasta scores: E(): 1.9e-13, 28.5% id in 228 aa 23612621 Similar to Saccharomyces cerevisiae kinesin-like protein kip1 kip1 or cin9 or ybl063w or ybl0504 or ybl0521 SWALL:KIP1_YEAST (SWALL:P28742) blast scores: E(): 7e-26, score: 302 32% id, and to Drosophila melanogaster kinesin-like protein klp68d klp68d or klp5 or cg7293 SWALL:KL68_DROME (SWALL:P46867) (784 aa) fasta scores: E(): 5.2e-13, 24.19% id in 587 aa, and to Plasmodium falciparum putative kinesin-related protein pfc0770c, mal3p6.13 SWALL:O77382 (EMBL:Z98551) (1619 aa) fasta scores: E(): 1.7e-25, 23.31% id in 1703 aa 23612622 Similar to Saccharomyces cerevisiae exonuclease i exo1 or dhs1 or yor033c or or26.23 SWALL:EXO1_YEAST (SWALL:P39875) (702 aa) fasta scores: E(): 1.9e-15, 22.72% id in 704 aa, and to Homo sapiens exonuclease 1 SWALL:Q96IJ1 (EMBL:BC007491) (846 aa) fasta scores: E(): 2.3e-17, 36.5% id in 200 aa 23612624 Similar to Homo sapiens mago nashi protein homolog magoH SWALL:MGN_HUMAN (SWALL:P50606) (146 aa) fasta scores: E(): 8.9e-37, 71.94% id in 139 aa, and to Oryza sativa mago nashi-like protein SWALL:Q9AXD9 (EMBL:AF338343) (160 aa) fasta scores: E(): 1.1e-36, 69.28% id in 140 aa 23612629 Conserved hypothetical protein in P. falciparum; similar to SWALL:Q9Y012 (EMBL:AL034560) Similar to Plasmodium falciparum Pfc0060c, mal3p8.10 protein pfc0060c, mal3p8.10 SWALL:Q9Y012 (EMBL:AL034560) (587 aa) fasta scores: E(): 3.6e-43, 41.29% id in 557 aa 23612630 Similar to Saccharomyces cerevisiae DNA mismatch repair protein pms1 pms1 or ynl082w or n2317 SWALL:PMS1_YEAST (SWALL:P14242) (904 aa) fasta scores: E(): 1.1e-21, 27.77% id in 731 aa, and to Schizosaccharomyces pombe DNA mismatch repair protein pms1 pms1 or spac19g12.02C SWALL:PMS1_SCHPO (SWALL:P54280) (794 aa) fasta scores: E(): 5.3e-29, 28.7% id in 627 aa 23612631 Existence of small introns uncertain 23612632 Similar to Schizosaccharomyces pombe ubiquitin carboxyl-terminal hydrolase ubpd ubpd or spbc713.02C SWALL:UBPD_SCHPO (SWALL:Q9UTT1) (1129 aa) fasta scores: E(): 1.5e-27, 31.15% id in 504 aa, and to Homo sapiens ubiquitin carboxyl-terminal hydrolase 7 usp7 or hausP SWALL:UBP7_HUMAN (SWALL:Q93009) blast scores: E(): 4e-52, score: 528 34% id, and to Arabidopsis thaliana ubiquitin carboxyl-terminal hydrolase SWALL:Q9FG10 (EMBL:AP002543) blast scores: E(): 4e-59, score: 587 39% id 23612635 Similar to Schizosaccharomyces pombe hypothetical 52.6 kDa protein pi044 or spbc8d2.21c or spbc17a3.01C SWALL:O13636 (EMBL:AB004537) (452 aa) fasta scores: E(): 1.1e-13, 26.76% id in 396 aa, and to Saccharomyces cerevisiae ypl063wp protein ypl063w or lpe7W SWALL:Q02776 (EMBL:U39205) (476 aa) fasta scores: E(): 2e-13, 28.38% id in 303 aa, and to Schizosaccharomyces pombe hypothetical 52.6 kDa protein pi044 or spbc8d2.21c or spbc17a3.01C SWALL:O13636 (EMBL:AB004537) blast scores: E(): 2e-17, score: 92 30% id 23612637 Existence of the intron is uncertain; alternative start site possible 23612638 Similar to Rickettsia conorii cysteine desulfurase iscs or spl1 or rc0731 SWALL:ISCS_RICCN (SWALL:Q92HP1) (410 aa) fasta scores: E(): 1.8e-79, 54.68% id in 406 aa, and to Drosophila melanogaster probable cysteine desulfurase, mitochondrial precursor cg12264 SWALL:NFS1_DROME (SWALL:Q9VKD3) (462 aa) fasta scores: E(): 1.5e-79, 50.44% id in 452 aa 23612639 EC_number 2.1.1.173 GO assignment and EC numbers have been assigned with the assumption that this proteins functions as a modification methylase Similar to Homo sapiens DNA dnmt2 SWALL:DNM2_HUMAN (SWALL:O14717) blast scores: E(): 2e-11, score: 72 46% id, and to Zea mays DNA methyltransferase zmet4 SWALL:Q94IR0 (EMBL:AY029557) blast scores: E(): 8e-10, score: 67 37% id, and to Drosophila melanogaster mt2 protein mt2 or cg10692 SWALL:Q9VKB3 (EMBL:AE003635) blast scores: E(): 1e-07, score: 60 35% id 23612640 Similar to Drosophila melanogaster proteasome subunit alpha type 5 prosma5 or cg10938 SWALL:PSA5_DROME (SWALL:Q95083) (244 aa) fasta scores: E(): 2e-50, 53.52% id in 241 aa, and to Trypanosoma brucei brucei proteasome subunit alpha type 5 SWALL:PSA5_TRYBB (SWALL:Q9XZG5) (246 aa) fasta scores: E(): 1.9e-49, 52.47% id in 242 aa 23612644 Although fasta and Blastp hits indicate it is a potential cation-transporting ATPase; HMMPfam search does produce significant hit to E1_E2_ATPase and Hydrolase domains, present in other cation-transporting ATPases Similar to Arabidopsis thaliana potential cation-transporting ATPase at5g23630 or mqm1.11 SWALL:ATX1_ARATH (SWALL:Q9LT02) blast scores: E(): 2e-43, score: 451 31% id, and to Dictyostelium discoideum putative cation-transporting ATPase CtaA ctaA SWALL:Q9NGW7 (EMBL:AF238314) (1208 aa) fasta scores: E(): 3.2e-21, 26.23% id in 1418 aa, and to Homo sapiens probable cation-transporting ATPase 2 kiaa1825 SWALL:ATY2_HUMAN (SWALL:Q9HD20) (1204 aa) fasta scores: E(): 7.1e-21, 25.77% id in 1447 aa 23612646 Similar to Schizosaccharomyces pombe eukaryotic translation initiation factor 2 alpha subunit tif211 or spac3g9.09C SWALL:IF2A_SCHPO (SWALL:P56286) (306 aa) fasta scores: E(): 2.4e-47, 48.36% id in 306 aa 23612654 Similar to Arabidopsis thaliana signal recognition particle 9 kDa protein srp9 or at3g49100 or t2j13.60 SWALL:SR09_ARATH (SWALL:Q9SMU7) blast scores: E(): 1e-08, score: 60 34% id, and to Zea mays signal recognition particle 9 kDa protein srp9 SWALL:SR09_MAIZE (SWALL:O04438) (103 aa) fasta scores: E(): 1e-05, 27.72% id in 101 aa, and to Arabidopsis thaliana signal recognition particle 9 kDa protein srp9 or at3g49100 or t2j13.60 SWALL:SR09_ARATH (SWALL:Q9SMU7) (103 aa) fasta scores: E(): 8.6e-06, 28.84% id in 104 aa 23612656 Similar to Anabaena sp. peroxiredoxin 2 family protein/glutaredoxin all1541 SWALL:Q8YWR3 (EMBL:AP003586) blast scores: E(): 2e-28, score: 313 42% id, and to Rhizobium loti peroxiredoxin 2 family protein mll5873 SWALL:Q98AS5 (EMBL:AP003007) (182 aa) fasta scores: E(): 6.7e-22, 42.03% id in 157 aa, and to Synechocystis sp. hypothetical protein Sll1621 sll1621 SWALL:YG21_SYNY3 (SWALL:P73728) (189 aa) fasta scores: E(): 1.4e-19, 40% id in 155 aa 23612657 Similar to Schizosaccharomyces pombe hypothetical protein c16c9.03 in chromosome i spac16c9.03 SWALL:YAC3_SCHPO (SWALL:Q09817) blast scores: E(): 4e-45, score: 463 32% id 23612658 Similar to Caenorhabditis elegans hypothetical 40.2 kDa protein K12h4.3 in chromosome iii k12h4.3 SWALL:YM63_CAEEL (SWALL:P34524) (352 aa) fasta scores: E(): 1.1e-20, 33.55% id in 295 aa 23612662 Similar to Schizosaccharomyces pombe dynein light chain 1, cytoplasmic dlc2 or spac926.07C SWALL:DYL1_SCHPO (SWALL:Q9UR05) (85 aa) fasta scores: E(): 0.0045, 30.12% id in 83 aa 23612663 Similar to Drosophila melanogaster dynein heavy chain, cytosolic cdhc or dhc64C SWALL:DYHC_DROME (SWALL:P37276) (4639 aa) fasta scores: E(): 2.4e-213, 38.92% id in 4840 aa 23612665 Similar to Saccharomyces cerevisiae hypothetical 77.0 kDa protein in hes1-sec63 intergenic region yor243c or o5254 SWALL:YO7T_YEAST (SWALL:Q08647) (676 aa) fasta scores: E(): 5.4e-10, 34.02% id in 194 aa 23612666 Similar to Mus musculus adapter-related protein complex 4 beta 1 subunit ap4b1 SWALL:A4B1_MOUSE (SWALL:Q9WV76) (739 aa) fasta scores: E(): 5.2e-53, 32.11% id in 576 aa, and to Homo sapiens adapter-related protein complex 4 beta 1 subunit ap4b1 SWALL:A4B1_HUMAN (SWALL:Q9Y6B7) (739 aa) fasta scores: E(): 1.9e-53, 31.24% id in 621 aa 36329003956 Last exon uncertain; alternative model possible for exon I 23612667 Similar to Homo sapiens regulator of nonsense transcripts 1 rent1 or hupf1 or kiaa0221 SWALL:RNT1_HUMAN (SWALL:Q92900) (1129 aa) fasta scores: E(): 1.2e-25, 28.16% id in 735 aa, and to Neurospora crassa regulator of nonsense transcripts 1 homolog 2e4.130 SWALL:RNT1_NEUCR (SWALL:Q9HEH1) (1093 aa) fasta scores: E(): 6.5e-24, 34.97% id in 466 aa 23612671 Similar to Plasmodium falciparum hypothetical 7.3 kDa protein SWALL:Q9NFG8 (EMBL:AJ290929) (66 aa) fasta scores: E(): 4.3e-14, 95.38% id in 65 aa 36329003966 Similar to Plasmodium falciparum Pfc0060c, mal3p8.10 protein pfc0060c, mal3p8.10 SWALL:Q9Y012 (EMBL:AL034560) (587 aa) fasta scores: E(): 6.7e-49, 38.85% id in 525 aa 23612676 Similar to Plasmodium falciparum erythrocyte binding antigen eba-175 SWALL:Q05644 (EMBL:U32207) (1421 aa) fasta scores: E(): 0, 100% id in 1421 aa 23612677 Similar to Plasmodium falciparum ATP-dept. acyl-coa synthetase pfb0695C SWALL:O96232 (EMBL:AE001412) (888 aa) fasta scores: E(): 1.9e-117, 57.77% id in 817 aa 23612678 Similar to Plasmodium falciparum predicted integral membrane protein pfb0075C SWALL:O96120 (EMBL:AE001369) (254 aa) fasta scores: E(): 2.5e-09, 33.56% id in 146 aa 23612680 Similar to Plasmodium falciparum stevor pfc1105w, mal3p7.52 SWALL:Q9U5M0 (EMBL:AL034559) (301 aa) fasta scores: E(): 1.7e-70, 74.81% id in 274 aa, and to Plasmodium falciparum hypothetical 33.3 kDa protein stevor 3d73-2 SWALL:O96489 (EMBL:AF065199) (296 aa) fasta scores: E(): 4.4e-76, 80.29% id in 269 aa 36329003972 Similar to Plasmodium falciparum pfemp1 pfb0045C SWALL:O96115 (EMBL:AE001368) (248 aa) fasta scores: E(): 2.4e-77, 99.52% id in 211 aa 23612681 Similar to Plasmodium falciparum rifin pfb1010W SWALL:O96289 (EMBL:AE001432) (368 aa) fasta scores: E(): 1.7e-68, 54.69% id in 373 aa 23612682 Similar to Plasmodium falciparum rifin pfb0040C SWALL:O96114 (EMBL:AE001367) (330 aa) fasta scores: E(): 6.1e-52, 50.15% id in 333 aa 23612683 Similar to Plasmodium falciparum rifin pfb0030C SWALL:O96112 (EMBL:AE001367) (370 aa) fasta scores: E(): 1e-58, 50.9% id in 385 aa 23612684 Similar to Plasmodium falciparum rifin pfb1010W SWALL:O96289 (EMBL:AE001432) (368 aa) fasta scores: E(): 3.6e-55, 52.43% id in 370 aa 23612685 Similar to Plasmodium falciparum rifin pfb1040W SWALL:O96293 (EMBL:AE001433) (345 aa) fasta scores: E(): 1.9e-75, 70.43% id in 345 aa 23612686 Similar to Plasmodium falciparum rifin pfb1040W SWALL:O96293 (EMBL:AE001433) (345 aa) fasta scores: E(): 4.3e-66, 70.76% id in 301 aa 23612687 Similar to Plasmodium falciparum rifin, Mal1p4.07 mal1p4.07 SWALL:Q9NFB0 (EMBL:AL031747) (344 aa) fasta scores: E(): 3.7e-71, 60.11% id in 346 aa 23612688 Similar to Plasmodium falciparum pfemp1 pfb1055C SWALL:O96296 (EMBL:AE001434) (2197 aa) fasta scores: E(): 1.4e-132, 44.96% id in 2720 aa 23612711 Similar to Plasmodium falciparum hypothetical 192.3 kDa protein mal1p3.07 SWALL:Q9U0N0 (EMBL:AL031746) (1555 aa) fasta scores: E(): 3.5e-51, 32.25% id in 1423 aa, and to Plasmodium vivax Pvstp1 protein pvstp1 SWALL:Q9N894 (EMBL:AL360354) (826 aa) fasta scores: E(): 8.3e-16, 25.64% id in 815 aa, and to Plasmodium falciparum hypothetical 192.3 kDa protein mal1p3.07 SWALL:Q9U0N0 (EMBL:AL031746) (1555 aa) fasta scores: E(): 3.3e-51, 32.25% id in 1423 aa 23612712 Similar to Plasmodium falciparum protein with DNAJ domain pfb0085C SWALL:O96122 (EMBL:AE001370) (900 aa) fasta scores: E(): 2.7e-09, 24.7% id in 340 aa 23612714 Similar to Plasmodium falciparum hypothetical 192.3 kDa protein mal1p3.07 SWALL:Q9U0N0 (EMBL:AL031746) (1555 aa) fasta scores: E(): 1.7e-19, 29.19% id in 1360 aa, and to Plasmodium falciparum hypothetical 192.3 kDa protein mal1p3.07 SWALL:Q9U0N0 (EMBL:AL031746) (1555 aa) fasta scores: E(): 1.7e-19, 29.19% id in 1360 aa 23612715 Similar to Plasmodium falciparum predicted integral membrane protein pfb0930W SWALL:O96278 (EMBL:AE001427) (225 aa) fasta scores: E(): 1.2e-06, 33.76% id in 234 aa 23612717 Similar to Plasmodium yoelii blood-stage membrane protein ag-1 SWALL:O96672 (EMBL:AF103869) (549 aa) fasta scores: E(): 8e-32, 27.77% id in 468 aa, and to Plasmodium falciparum tryptophan/threonine-rich antigen SWALL:Q95UT5 (EMBL:AY027491) (675 aa) fasta scores: E(): 0, 99.4% id in 675 aa 23612724 Similar to Mus musculus u6 snrna-associated sm-like protein lsm8 SWALL:AAH19458 (EMBL:BC019458) (96 aa) fasta scores: E(): 4.6e-12, 45.26% id in 95 aa, and to Drosophila melanogaster Cg2021 protein cg2021 SWALL:Q9W087 (EMBL:AE003472) (95 aa) fasta scores: E(): 8e-13, 46.66% id in 90 aa 23612725 Similar to Nicotiana tabacum prohibitin SWALL:O04361 (EMBL:U69154) (279 aa) fasta scores: E(): 7.6e-52, 53.99% id in 263 aa 23612726 Similar to Homo sapiens similar to riken cDNA 1810023b24 gene SWALL:Q96CT7 (EMBL:BC013949) (223 aa) fasta scores: E(): 0.00013, 30.65% id in 274 aa 23612731 Similar to Synechocystis sp. integral membrane protein slr0642 SWALL:Q55721 (EMBL:D64002) (494 aa) fasta scores: E(): 8.1e-32, 30.73% id in 397 aa, and to Synechococcus sp. hypothetical 49.2 kDa protein SWALL:O68867 (EMBL:AF055873) (453 aa) fasta scores: E(): 6.7e-32, 29.64% id in 398 aa 23612732 Similar to Arabidopsis thaliana putative translation initiation factor eif-2b alpha subunit, 76271- 74747 t10d10.19 SWALL:Q9C9D3 (EMBL:AC016529) (362 aa) fasta scores: E(): 3.9e-07, 23.88% id in 335 aa 23612735 Similar to Staphylococcus aureus leucyl-rRNA synthetase leus or sav1760 or sa1579 SWALL:Q99TA8 (EMBL:AP003363) (804 aa) fasta scores: E(): 8.8e-32, 29.55% id in 812 aa 23612738 Similar to Plasmodium falciparum putative disulfide isomerase precursor SWALL:Q9GRI2 (EMBL:AJ250363) (483 aa) fasta scores: E(): 2.5e-189, 99.17% id in 483 aa 23612742 N-terminal extension is possible transit peptide Similar to Odontella sinensis chloroplast 50s ribosomal protein l21 rpl21 SWALL:RK21_ODOSI (SWALL:P49557) (105 aa) fasta scores: E(): 9.7e-13, 43.81% id in 105 aa 23612745 Similar to Plasmodium falciparum 8b2 proteiN 8b2 proteiN SWALL:Q25779 (EMBL:L06303) (286 aa) fasta scores: E(): 5.1e-82, 99.29% id in 284 aa 23612746 Similar to Drosophila melanogaster Cg12413 protein cg12413 SWALL:Q9VAV2 (EMBL:AE003765) (621 aa) fasta scores: E(): 3.2e-16, 32.36% id in 346 aa 23612747 Similar to Arabidopsis thaliana F22k20.13 protein f22k20.13 SWALL:O49289 (EMBL:AC002291) (845 aa) fasta scores: E(): 5e-31, 34.96% id in 409 aa 23612749 Similar to Euprymna scolopes guanine nucleotide-binding protein rackI SWALL:Q9U4Y2 (EMBL:AF124742) (313 aa) fasta scores: E(): 1.4e-77, 61.66% id in 313 aa 23612752 Similar to Saccharomyces cerevisiae putative dehydrodolichyl diphosphate synthetase srt1 or ymr101c or ym6543.08C SWALL:SRT1_YEAST (SWALL:Q03175) (343 aa) fasta scores: E(): 7.7e-13, 35.59% id in 177 aa, and to Thermoplasma acidophilum hypothetical protein Ta0546 ta0546 SWALL:Q9HKQ0 (EMBL:AL445064) (258 aa) fasta scores: E(): 2.7e-14, 31.07% id in 251 aa 23612753 Similar to Mus musculus similar to ash2 ash2L SWALL:Q91X20 (EMBL:BC012957) (623 aa) fasta scores: E(): 1.9e-11, 30.13% id in 219 aa 23612754 Similar to Plasmodium falciparum Pfc0065c,mal3p8.11 protein pfc0065c,mal3p8.11 SWALL:Q9Y013 (EMBL:AL034560) (437 aa) fasta scores: E(): 5.5e-50, 41.13% id in 423 aa 23612755 Similar to Arabidopsis thaliana ubiquitin-protein ligase 1 upl1 SWALL:Q9M7K7 (EMBL:AF127564) (3681 aa) fasta scores: E(): 9.6e-57, 50.94% id in 424 aa 23612769 Similar to Drosophila melanogaster cg4180 protein l(2)35bg or cg4180 SWALL:Q9V3Y2 (EMBL:AE003646) (248 aa) fasta scores: E(): 7.4e-11, 42.27% id in 123 aa 23612771 Similar to Plasmodium falciparum nucleoside transporter 1 nt1 SWALL:Q9NIH8 (EMBL:AF211121) (422 aa) fasta scores: E(): 7.3e-07, 26.73% id in 202 aa 23612772 Similar to Rickettsia conorii GTP-binding protein obg or rc1307 SWALL:Q92G19 (EMBL:AE008677) (362 aa) fasta scores: E(): 6.4e-18, 28.73% id in 355 aa 23612774 Similar to Plasmodium falciparum protein with egl-like 3'-5' exonucl. domain pfb0215C SWALL:O96144 (EMBL:AE001381) (416 aa) fasta scores: E(): 5.9e-11, 27.16% id in 438 aa 23612776 Similar to Arabidopsis thaliana putative oxoglutarate/malate translocator protein SWALL:Q9C5M0 (EMBL:AF360153) (298 aa) fasta scores: E(): 7.1e-55, 52.04% id in 294 aa 23612779 Similar to SWALL:Q9S2P3 (EMBL:UNKNOWN ACCESSION) (265 aa) fasta scores: E(): 5.5e-06, 28.81% id in 177 aa 23612780 Similar to Plasmodium falciparum hypothetical 61.8 kDa protein pfc0185w, mal3p2.6 SWALL:O97229 (EMBL:AL034558) (525 aa) fasta scores: E(): 3.7e-13, 26.58% id in 459 aa, and to Plasmodium vivax pv1h14125_p pv1h14125W SWALL:Q962K9 (EMBL:AY003872) (529 aa) fasta scores: E(): 6.2e-10, 26.06% id in 445 aa 23612782 Similar to Toxoplasma gondii histone acetyltransferase Gcn5 gcn5 SWALL:Q9NIS0 (EMBL:AF197953) (1169 aa) fasta scores: E(): 2.2e-36, 43.98% id in 648 aa 23612783 Similar to Homo sapiens RNA-binding protein Brunol1 brunol1 SWALL:Q9HB30 (EMBL:AF284423) (140 aa) fasta scores: E(): 2.4e-11, 49.41% id in 85 aa 23612787 Similar to Homo sapiens u5 snrnp-specific 40 kDa protein SWALL:O95320 (EMBL:AF090988) (357 aa) fasta scores: E(): 1.1e-39, 35.71% id in 308 aa, and to Caenorhabditis elegans hypothetical 36.8 kDa protein c18e3.5 SWALL:O02097 (EMBL:AF000265) (331 aa) fasta scores: E(): 4.4e-40, 35.48% id in 310 aa 23612790 Similar to Homo sapiens protein transport protein Sec23A sec23A SWALL:S23A_HUMAN (SWALL:Q15436) (765 aa) fasta scores: E(): 9.3e-150, 47.72% id in 769 aa 23612791 Similar to Anthocidaris crassispina outer arm dynein light chain 2 SWALL:O44230 (EMBL:AB010054) (199 aa) fasta scores: E(): 6.1e-23, 46.35% id in 192 aa 23612793 Similar to Arabidopsis thaliana putative small nuclear ribonucleoprotein polypeptide g, 65009- 64161 f24k9.17 or at3g11500, f24k9.17 SWALL:AAL32896 (EMBL:AC008153) (79 aa) fasta scores: E(): 3e-14, 56.57% id in 76 aa 23612796 Similar to Arabidopsis thaliana 50s ribosomal protein l4 at2g20060 SWALL:Q9SL75 (EMBL:AY072419) (266 aa) fasta scores: E(): 8e-08, 24.58% id in 240 aa 23612797 Alternative gene model possible 23612798 Similar to Saccharomyces cerevisiae protein transport protein sec61 beta 1 subunit seb1 or sbh1 or yer087bC SWALL:S6B1_YEAST (SWALL:P52870) (82 aa) fasta scores: E(): 4.3e-05, 36.58% id in 82 aa 23612799 Similar to Spodoptera frugiperda ribosomal protein l22 SWALL:Q962T6 (EMBL:AF400188) (147 aa) fasta scores: E(): 8.8e-17, 47.1% id in 138 aa 23612801 Similar to Homo sapiens probable ribosome biogenesis protein nep1 c2F SWALL:NEP1_HUMAN (SWALL:Q92979) (244 aa) fasta scores: E(): 1.5e-21, 36.32% id in 212 aa, and to Caenorhabditis elegans probable ribosome biogenesis protein nep1 y39a1a.14 SWALL:NEP1_CAEEL (SWALL:Q9XX15) (231 aa) fasta scores: E(): 1.7e-21, 36.07% id in 219 aa, and to Schizosaccharomyces pombe multicopy suppressor of ras1 mra1 or spac18g6.07C SWALL:MRA1_SCHPO (SWALL:Q10107) (359 aa) fasta scores: E(): 4.3e-21, 33.95% id in 268 aa 23612802 Alternative gene model possible 23612803 Similar to Schizosaccharomyces pombe probable ATP-dependent RNA helicase prh1 prh1 or spac2g11.11C SWALL:PRH1_SCHPO (SWALL:Q03319) (719 aa) fasta scores: E(): 2.6e-26, 28.45% id in 854 aa 23612805 Similar to Plasmodium falciparum protein kinase pk1 SWALL:Q27739 (EMBL:X83707) (909 aa) fasta scores: E(): 0, 98.91% id in 919 aa 23612809 Similar to Saccharomyces cerevisiae 2-oxoglutarate dehydrogenase e1 component, mitochondrial precursor kgd1 or yil125W SWALL:ODO1_YEAST (SWALL:P20967) (1014 aa) fasta scores: E(): 5.6e-148, 41.29% id in 1017 aa 23612811 Similar to Plasmodium falciparum C-13 antigen c-13 SWALL:O96563 (EMBL:AF091239) (503 aa) fasta scores: E(): 1.1e-154, 95.63% id in 504 aa 23612814 Similar to Plasmodium falciparum phosphatidylglycerophosphate synthase SWALL:Q9BMH1 (EMBL:AF325455) (659 aa) fasta scores: E(): 0, 99.54% id in 661 aa 23612816 Similar to Drosophila melanogaster helicase domino a dom or cg9696 SWALL:Q9NDJ2 (EMBL:AF076776) (3201 aa) fasta scores: E(): 4e-57, 26.78% id in 1665 aa 23612817 Similar to Homo sapiens u6 snrna-associated sm-like protein Lsm3 lsm3 SWALL:LSM3_HUMAN (SWALL:Q9Y4Z1) (101 aa) fasta scores: E(): 6.2e-09, 47.43% id in 78 aa, and to Dictyostelium discoideum putative ribonucleoprotein SWALL:AAL92692 (EMBL:AC115683) (98 aa) fasta scores: E(): 9.3e-12, 53.94% id in 76 aa 23612821 Similar to Encephalitozoon cuniculi hypothetical protein Ecu07_1320 ecu07_1320 SWALL:CAD25665 (EMBL:AL590447) (334 aa) fasta scores: E(): 4.9e-16, 35.64% id in 216 aa 23612827 Similar to Plasmodium falciparum heat shock 70 kDa protein SWALL:HS70_PLAFA (SWALL:P11144) (681 aa) fasta scores: E(): 7.6e-217, 99.41% id in 681 aa 23612828 Similar to Arabidopsis thaliana putative u3 small nucleolar ribonucleoprotein protein t12p18.20 or f24d7.3 or at1g63780 SWALL:Q9S826 (EMBL:AC010852) (294 aa) fasta scores: E(): 1.1e-26, 32.14% id in 364 aa, and to Drosophila melanogaster Cg11920 protein cg11920 SWALL:Q9VBY2 (EMBL:AE003750) (298 aa) fasta scores: E(): 4.1e-28, 35.44% id in 364 aa 23612831 Similar to Homo sapiens zinc finger protein 216 znf216 SWALL:CAD13440 (EMBL:AF062072) (213 aa) fasta scores: E(): 2.4e-09, 33.64% id in 217 aa, and to Caenorhabditis elegans F22d6.2 protein f22d6.2 SWALL:Q19723 (EMBL:Z71262) (189 aa) fasta scores: E(): 6.5e-13, 29.59% id in 196 aa 23612834 Similar to Homo sapiens 14-3-3 protein epsilon ywhaE SWALL:143E_HUMAN (SWALL:P42655) (255 aa) fasta scores: E(): 7.2e-55, 63.82% id in 246 aa, and to Plasmodium knowlesi 14-3-3 protein SWALL:O61131 (EMBL:AF065986) (262 aa) fasta scores: E(): 4.4e-93, 98.41% id in 253 aa 23612837 Similar to Plasmodium falciparum high mobility group protein SWALL:Q25871 (EMBL:L31630) (97 aa) fasta scores: E(): 2.7e-16, 63.33% id in 90 aa 23612841 Similar to Arabidopsis thaliana protein kinase c inhibitor-like protein t5p19_140 SWALL:Q9LXZ1 (EMBL:AL163972) (129 aa) fasta scores: E(): 1.5e-26, 52.67% id in 131 aa 23612843 Similar to Plasmodium falciparum asparagine-rich antigen SWALL:Q25774 (EMBL:X17489) (419 aa) fasta scores: E(): 4.1e-125, 99.52% id in 420 aa 23612847 Similar to Plasmodium falciparum meiotic recombination protein dmc1-like protein SWALL:Q967Y1 (EMBL:AF356553) (347 aa) fasta scores: E(): 9.7e-130, 97.98% id in 347 aa 23612850 Similar to Babesia bovis small heat shock protein SWALL:Q9BMF0 (EMBL:AF331455) (177 aa) fasta scores: E(): 1.6e-24, 44% id in 175 aa 23612853 Similar to Caenorhabditis elegans Y46g5a.12 protein y46g5a.12 SWALL:Q9U2F6 (EMBL:AL110485) (237 aa) fasta scores: E(): 2.2e-12, 32.55% id in 172 aa 23612854 Similar to Fowlpox virus orf Fpv114 hal3 domain fpv114 SWALL:Q9J5A8 (EMBL:AF198100) (183 aa) fasta scores: E(): 1.5e-27, 45.98% id in 187 aa 23612855 Similar to Caenorhabditis elegans Y54h5a.1 protein y54h5a.1 SWALL:Q9N393 (EMBL:AC024818) (453 aa) fasta scores: E(): 2.4e-17, 28.77% id in 497 aa 23612856 Similar to Oryza sativa putative lipoamide dehydrogenase p0487e11.16 SWALL:Q94CN9 (EMBL:AP003793) (561 aa) fasta scores: E(): 3.4e-30, 38.66% id in 538 aa 23612859 Similar to Mus musculus eukaryotic translation initiation factor 3 subunit 4 eif3s4 or eif3p42 SWALL:Q9R079 (EMBL:U70733) (320 aa) fasta scores: E(): 2.5e-11, 28.43% id in 313 aa 23612863 Similar to Arabidopsis thaliana importin beta SWALL:Q9FJD4 (EMBL:AB015476) (870 aa) fasta scores: E(): 2.9e-73, 30.61% id in 846 aa 23612866 Similar to Plasmodium falciparum fe-superoxide dismutase soD SWALL:Q27740 (EMBL:Z49819) (198 aa) fasta scores: E(): 7.2e-84, 99.49% id in 198 aa, and to Plasmodium falciparum superoxide dismutase [mn/fe] SWALL:Q9TW89 (EMBL:AF113156) (198 aa) fasta scores: E(): 3.4e-84, 100% id in 198 aa 23612873 Similar to Sulfolobus tokodaii putative sav protein st0209 SWALL:Q976H7 (EMBL:AP000981) (689 aa) fasta scores: E(): 8.9e-33, 41.26% id in 332 aa 23612874 Similar to Arabidopsis thaliana at1g20220/t20h2_3 SWALL:Q944A2 (EMBL:AF439833) (315 aa) fasta scores: E(): 4.1e-21, 41.87% id in 246 aa 23612876 Similar to Drosophila melanogaster 60S ribosomal protein l13 rpl13 or bbc1 or cg4651 SWALL:RL13_DROME (SWALL:P41126) (218 aa) fasta scores: E(): 1.3e-23, 39.62% id in 212 aa 23612877 Similar to Euphorbia esula 40s ribosomal protein s16 SWALL:Q9M5L1 (EMBL:AF227979) (144 aa) fasta scores: E(): 3.3e-35, 64.78% id in 142 aa 23612878 Similar to Rhizobium loti gdp-mannose 4,6-dehydratase, nodulation protein, noel mlr5849 SWALL:Q98AU5 (EMBL:AP003007) (366 aa) fasta scores: E(): 1.1e-76, 57.94% id in 340 aa 23612890 Similar to Nicotiana tabacum ubiquitin-conjugating enzyme e2 ntubc2 SWALL:Q9AVN9 (EMBL:AB026056) (152 aa) fasta scores: E(): 4.4e-42, 65.1% id in 149 aa 23612891 Similar to Drosophila melanogaster bcdna:gh01073 protein bcdna:gh01073 or cg5808 SWALL:Q9XYZ6 (EMBL:AE003749) (653 aa) fasta scores: E(): 8e-27, 31.23% id in 509 aa, and to Paramecium tetraurelia cyclophilin-RNA interacting protein kin241 SWALL:Q9BHM3 (EMBL:AJ409115) (695 aa) fasta scores: E(): 7.3e-25, 29.02% id in 534 aa 23612892 Similar to Arabidopsis thaliana importin alpha f3e22.14 SWALL:O81520 (EMBL:AF077528) (532 aa) fasta scores: E(): 2.3e-85, 49.9% id in 527 aa 23612903 Similar to Schizosaccharomyces pombe hypothetical protein c22h10.08 in chromosome i spac22h10.08 SWALL:YD48_SCHPO (SWALL:Q10301) (492 aa) fasta scores: E(): 7.2e-28, 40.93% id in 513 aa 23612907 Similar to Oryza sativa cullin-like protein p0560b06.30 or p0043b10.22 SWALL:Q93VH7 (EMBL:AP003281) (732 aa) fasta scores: E(): 7.4e-20, 24.43% id in 798 aa 23612909 Similar to Plasmodium falciparum dihydropteroate synthetase SWALL:Q25704 (EMBL:U07706) (706 aa) fasta scores: E(): 0, 99.85% id in 706 aa 23612911 Similar to Dugesia japonica DjvlgB djvlgB SWALL:O97032 (EMBL:AB017003) (781 aa) fasta scores: E(): 1.6e-35, 36.34% id in 776 aa, and to Dictyostelium discoideum putative RNA helicase hel2B SWALL:Q23910 (EMBL:X81824) (566 aa) fasta scores: E(): 2.9e-35, 34.88% id in 579 aa 23612912 Similar to Rattus norvegicus protein phosphatase 2c SWALL:Q9Z1Z6 (EMBL:AF095927) (392 aa) fasta scores: E(): 6.1e-19, 30.34% id in 290 aa 23612914 Similar to Arabidopsis thaliana hypothetical 35.1 kDa protein f26p21.70 or at4g32950 SWALL:O82637 (EMBL:AL031804) (326 aa) fasta scores: E(): 8.4e-10, 33.17% id in 208 aa 23612915 Similar to Arabidopsis thaliana abc1 protein abc1aT SWALL:O65576 (EMBL:AJ001158) (623 aa) fasta scores: E(): 5.1e-51, 41.43% id in 461 aa 23612916 Similar to Cyanophora paradoxa cyanelle 50s ribosomal protein l33 rpl33 SWALL:RK33_CYAPA (SWALL:P15769) (64 aa) fasta scores: E(): 7.3e-06, 49.2% id in 63 aa 23612917 Similar to Caenorhabditis elegans hypothetical 14.2 kDa protein F47b10.7 in chromosome x f47b10.7 SWALL:YAI7_CAEEL (SWALL:Q20507) (125 aa) fasta scores: E(): 2.6e-09, 37.64% id in 85 aa 23612919 Plasmodium specific conserved protein Similar to Plasmodium yoelii blood-stage membrane protein ag-1 SWALL:O96672 (EMBL:AF103869) (549 aa) fasta scores: E(): 1.3e-14, 36.91% id in 214 aa 23612920 Similar to Homo sapiens ruvb-like 1 tip49 SWALL:Q9Y265 (EMBL:Y18418) (456 aa) fasta scores: E(): 9.1e-74, 49.67% id in 461 aa, and to Arabidopsis thaliana ruv DNA-helicase-like protein SWALL:Q9FMR9 (EMBL:AB007651) (458 aa) fasta scores: E(): 5.2e-72, 51.19% id in 418 aa 23612924 Similar to Plasmodium falciparum asparagine-rich antigen Pfa55-14 pfa55-14 SWALL:Q03632 (EMBL:M59473) (307 aa) fasta scores: E(): 2.3e-99, 99.34% id in 307 aa 23612925 Similar to Plasmodium falciparum pfemp1 pfb1055C SWALL:O96296 (EMBL:AE001434) (2197 aa) fasta scores: E(): 1.3e-135, 44.04% id in 2300 aa 23612926 Similar to Plasmodium falciparum rifin pfb1050W SWALL:O96295 (EMBL:AE001434) (327 aa) fasta scores: E(): 2.3e-49, 48.62% id in 327 aa 23612927 Similar to Plasmodium falciparum rifin pfc1115w, mal3p7.54 SWALL:O97311 (EMBL:AL034559) (371 aa) fasta scores: E(): 2.9e-51, 47.86% id in 374 aa 23612928 Similar to Plasmodium falciparum var, mal4p2.58 mal4p2.58, vaR SWALL:Q9U0G5 (EMBL:AL035475) (2277 aa) fasta scores: E(): 3.6e-127, 52.41% id in 2385 aa 23612929 Similar to Plasmodium falciparum 3d7var1 3d7var1 SWALL:Q25766 (EMBL:U53324) (2042 aa) fasta scores: E(): 2e-124, 45.69% id in 2254 aa 23612932 Similar to Schistosoma mansoni aspartic proteinase precursor SWALL:P91802 (EMBL:U60995) (427 aa) fasta scores: E(): 2.7e-27, 32.65% id in 343 aa, and to Oryctolagus cuniculus pepsin iii precursor SWALL:PEP3_RABIT (SWALL:P27822) (387 aa) fasta scores: E(): 1.9e-27, 29.83% id in 362 aa, and to Xenopus laevis pepsinogen a SWALL:Q9DEC2 (EMBL:AB045380) (384 aa) fasta scores: E(): 3e-30, 33.33% id in 321 aa 23612935 Similar to Bos taurus tyrosyl-trna synthetase yars or tyrS SWALL:SYY_BOVIN (SWALL:Q29465) (528 aa) fasta scores: E(): 1.7e-25, 34.24% id in 330 aa, and to Nicotiana tabacum tyrosyl-trna synthetase tyrS SWALL:P93363 (EMBL:Y10990) (408 aa) fasta scores: E(): 4.7e-82, 60.88% id in 340 aa 23612937 Similar to Arabidopsis thaliana serine protease-like protein msn9.10 SWALL:Q9FL12 (EMBL:AB010699) (592 aa) fasta scores: E(): 3.5e-31, 31.58% id in 516 aa 23612939 Similar to Oryza sativa proteasome subunit alpha type 6 paa1 SWALL:PSA6_ORYSA (SWALL:Q9LSU3) (246 aa) fasta scores: E(): 9.4e-21, 40.84% id in 284 aa, and to Homo sapiens proteasome subunit alpha type 6 psma6 or pros27 SWALL:PSA6_HUMAN (SWALL:P34062) (246 aa) fasta scores: E(): 3.4e-22, 41.9% id in 284 aa 23612940 Similar to Lymnaea stagnalis ras-related protein rab-18a rab18A SWALL:RB18_LYMST (SWALL:Q05976) (202 aa) fasta scores: E(): 3.4e-33, 50.25% id in 193 aa, and to Plasmodium falciparum Rab18 gtpase rab18 SWALL:CAD27350 (EMBL:AJ438271) (201 aa) fasta scores: E(): 8.1e-74, 100% id in 201 aa 23612943 Similar to Gallus gallus Gas41 gas41 SWALL:Q8UVS4 (EMBL:AF410481) (227 aa) fasta scores: E(): 8.3e-16, 30.55% id in 216 aa, and to Homo sapiens gas41 protein SWALL:O95619 (EMBL:U61384) (227 aa) fasta scores: E(): 1.5e-15, 33.73% id in 166 aa 23612945 Similar to Rattus norvegicus vacuolar proton translocating ATPase 116 kDa subunit a isoform 1 atp6v0a1 or atp6n1 or vpp1 SWALL:VPP1_RAT (SWALL:P25286) (838 aa) fasta scores: E(): 1.9e-45, 28.89% id in 1066 aa 23612949 Similar to Arabidopsis thaliana hypothetical 19.6 kDa protein at4g16710 SWALL:O23514 (EMBL:Z97341) (176 aa) fasta scores: E(): 4.3e-10, 33.59% id in 128 aa, and to Schizosaccharomyces pombe hypothetical 17.8 kDa protein c56e4.02c in chromosome i spac56e4.02C SWALL:O14190 (EMBL:Z99261) (162 aa) fasta scores: E(): 1.5e-12, 32.94% id in 170 aa 23612958 Similar to Drosophila melanogaster cg11935 protein cg11935 or cg11938 SWALL:Q9VBX9 (EMBL:AE003750) (286 aa) fasta scores: E(): 3.4e-25, 36.05% id in 208 aa 23612960 Possibly apicoplast targeted Similar to Plasmodium falciparum peptidyl-prolyl cis-trans isomerase precursor cyP SWALL:Q27716 (EMBL:U10322) (210 aa) fasta scores: E(): 4.2e-85, 100% id in 210 aa 23612964 Similar to Homo sapiens methionine aminopeptidase 1 metap1 or kiaa0094 SWALL:AMP1_HUMAN (SWALL:P53582) (394 aa) fasta scores: E(): 1.9e-16, 32.41% id in 253 aa 23612966 Similar to Homo sapiens similar to cactin SWALL:Q9BTA6 (EMBL:BC004262) (183 aa) fasta scores: E(): 3e-17, 47.46% id in 158 aa 23612967 Similar to Plasmodium falciparum proteasome beta-subunit SWALL:Q9U570 (EMBL:AF090371) (265 aa) fasta scores: E(): 2.1e-104, 100% id in 265 aa 23612968 Similar to Plasmodium falciparum tubulin gamma chain g-tuB SWALL:TBG_PLAFO (SWALL:P34787) (452 aa) fasta scores: E(): 2.9e-173, 99.77% id in 452 aa 23612971 Similar to Arabidopsis thaliana DNA repair protein rad54-like SWALL:Q9LJK7 (EMBL:AP000419) (959 aa) fasta scores: E(): 1.1e-35, 32.68% id in 1028 aa 23612972 Similar to Arabidopsis thaliana similarity to unknown protein SWALL:Q9FGG0 (EMBL:AB025637) (343 aa) fasta scores: E(): 6.8e-17, 25.07% id in 319 aa 23612977 Similar to Paramecium tetraurelia protein phosphatase 2b SWALL:O15712 (EMBL:AF014922) (509 aa) fasta scores: E(): 1.4e-81, 55.93% id in 413 aa 23612980 Similar to Drosophila melanogaster Cg17840 protein cg17840 SWALL:Q9VR06 (EMBL:AE003576) (858 aa) fasta scores: E(): 8.4e-28, 25.83% id in 685 aa 23612982 Similar to Schizosaccharomyces pombe wd repeat protein spbc713.04C SWALL:Q9C1X1 (EMBL:AL512943) (854 aa) fasta scores: E(): 1.7e-09, 24.97% id in 1093 aa 23612983 Similar to Plasmodium falciparum 1-cys peroxidoxin 1-cyspxN SWALL:Q9XXW9 (EMBL:AB020595) (220 aa) fasta scores: E(): 2.5e-91, 100% id in 220 aa 23612985 Similar to Plasmodium falciparum glutamate dehydrogenase gdH SWALL:Q9NGT0 (EMBL:AF241225) (1378 aa) fasta scores: E(): 0, 98.9% id in 1368 aa 23612987 Weak but extended hit to Pfam amino oxidase domain, PF01593; possible flavin-containing amine oxidase (EC 1.4.3.-) 23612992 Similar to Drosophila melanogaster bg:ds01068.6 protein bg:ds01068.6 or cg7516 SWALL:Q9V3P2 (EMBL:AE003643) (721 aa) fasta scores: E(): 4.9e-28, 30% id in 550 aa 23612995 Similar to Plasmodium vivax von willebrand factor a-domain-related protein pvwarP SWALL:Q966V9 (EMBL:AB051630) (300 aa) fasta scores: E(): 5.1e-69, 67.54% id in 265 aa, and to Plasmodium berghei micronemal protein warp SWALL:Q963J7 (EMBL:AF364867) (303 aa) fasta scores: E(): 8.3e-68, 62.87% id in 299 aa 23612999 Similar to Plasmodium falciparum hypothetical 192.3 kDa protein mal1p3.07 SWALL:Q9U0N0 (EMBL:AL031746) (1555 aa) fasta scores: E(): 9e-50, 31.14% id in 1689 aa 23613001 Similar to Plasmodium falciparum rifin pfb0035C SWALL:O96113 (EMBL:AE001367) (375 aa) fasta scores: E(): 1.3e-64, 57.93% id in 378 aa 23613002 Similar to Plasmodium falciparum rifin pfc1115w, mal3p7.54 SWALL:O97311 (EMBL:AL034559) (371 aa) fasta scores: E(): 2.6e-75, 64.26% id in 375 aa 23613003 Similar to Plasmodium falciparum pfemp1 pfb1055C SWALL:O96296 (EMBL:AE001434) (2197 aa) fasta scores: E(): 2.6e-146, 41.56% id in 2401 aa 23613004 Similar to Plasmodium falciparum pfemp1 variant 1 of strain mc mcvar-1 pfemp1 SWALL:Q25733 (EMBL:U27338) (2924 aa) fasta scores: E(): 1.6e-149, 33.52% id in 3120 aa 23613005 Similar to Plasmodium falciparum 3d7var1 3d7var1 SWALL:Q25766 (EMBL:U53324) (2042 aa) fasta scores: E(): 1e-118, 48.04% id in 2146 aa 23613524 Similar to Plasmodium falciparum pfemp1 pfb1055C TR:O96296 (EMBL:AE001434) (2197 aa) fasta scores: E(): 8.2e-125, 49.894% id in 2353 aa. Pfam match to entry PF03011 PFEMP, , score 216.70, E-value 3.5e-61 23613525 Similar to Plasmodium falciparum Pfc1115W protein pfc1115W TR:O97311 (EMBL:AL034559) (371 aa) fasta scores: E(): 8.7e-63, 55.065% id in 385 aa. With single transmembrane domain. Pfam match to entry PF02009 Rifin_STEVOR, Rifin/stevor family, score 557.60, E-value 8.3e-164 23613526 similar to rifin from P. falciparum. With Transmebrane domain and N-terminal signal peptide. HMMPfam hit to PF02009, Rifin/stevor family 23613527 Similar to Plasmodium falciparum variant surface antigen rifin 1 rif1 TR:Q9U6Q4 (EMBL:AF180393) (337 aa) fasta scores: E(): 1.5e-59, 51.744% id in 344 aa. Similar to Rifin of P. falciparum. HMMPfam hit to PF02009, Rifin/stevor family 23613528 Similar to Plasmodium falciparum rifin pfb1040W TR:O96293 (EMBL:AE001433) (345 aa) fasta scores: E(): 4.4e-58, 58.166% id in 349 aa. Similar to Rifin of P. falciparum. With predicted N-terminal signal sequence and transmembrane domain sequence. HMMPfam hit to PF02009, Rifin/stevor family 23613529 Similar to Plasmodium falciparum Pfc1115W protein pfc1115W TR:O97311 (EMBL:AL034559) (371 aa) fasta scores: E(): 8.1e-58, 51.862% id in 376 aa. Similar to Rifin of P. falciparum. HMMPfam hit to PF02009, Rifin/stevor family 23613530 Similar to Plasmodium falciparum Pfc1115W protein pfc1115W TR:O97311 (EMBL:AL034559) (371 aa) fasta scores: E(): 5.1e-67, 66.404% id in 381 aa. Similar to Rifins from P. falciparum. With predicted N-terminal signal sequence. HMMPfam hit to PF02009, Rifin/stevor family 36329004283 varC-like pseudogene. Similar to Plasmodium falciparum pfemp1 fragment pfb0020C TR:O96110 (EMBL:AE001366) (440 aa) fasta scores: E(): 3.4e-71, 81.667% id in 240 aa 23613531 Similar to Plasmodium falciparum Mal3p8.4 protein mal3p8.4 TR:Q9U5L9 (EMBL:AL034560) (296 aa) fasta scores: E(): 2.7e-77, 75.085% id in 293 aa. Similarity with Rifin-Stevor like sequences from P. falcipaum. HMMPfam hit to PF02009, Rifin/stevor family 23613532 similar to Rifins of P. falciparum. With predicted N-terminal signal peptide and 2 transmembrane segments instead of /usual 1. HMMPfam hit to PF02009, Rifin/stevor family 23613533 Similar to Plasmodium falciparum RifiN, mal1p4.04 rifiN TR:Q9NFB3 (EMBL:AL031747) (372 aa) fasta scores: E(): 5.3e-51, 47.042% id in 355 aa. similar to Rifins of P. falciparum. HMMPfam hit to PF02009, Rifin/stevor family 23613534 Similar to Plasmodium falciparum hypothetical 7.9 kDa protein mal1p4.06 TR:Q9NFB1 (EMBL:AL031747) (67 aa) fasta scores: E(): 6.2e-16, 70.149% id in 67 aa 23613535 Similar to Plasmodium falciparum rifin pfb0030C TR:O96112 (EMBL:AE001367) (370 aa) fasta scores: E(): 7.8e-69, 58.575% id in 379 aa. With putative 1 transmembrane domain. HMMPfam hit to PF02009, Rifin/stevor family 23613536 Similar to Plasmodium falciparum rifin, Mal1p4.07 mal1p4.07 TR:Q9NFB0 (EMBL:AL031747) (344 aa) fasta scores: E(): 1.7e-78, 65.429% id in 350 aa. With putative 1 transmembrane domain. HMMPfam hit to PF02009, Rifin/stevor family 23613537 Similar to Plasmodium falciparum rifin pfb1010W TR:O96289 (EMBL:AE001432) (368 aa) fasta scores: E(): 9.5e-52, 47.872% id in 376 aa. Plasmodium falciparum Rifin. last exon doesn't end with a stop codon. Interpro match to Rifin_Stevor family. HMMPfam hit to PF02009, Rifin/stevor family 23613538 Similar to Plasmodium falciparum rifin pfb1020W TR:O96291 (EMBL:AE001433) (304 aa) fasta scores: E(): 7.7e-71, 66.238% id in 311 aa. HMMPfam hit to PF02009, Rifin/stevor family 23613539 Hypothetical protein with 2 transmembrane domain. 2 putative transmembaren domains identified by TMHMM 23613540 Hypothetical protein, with single C-terminal transmembrane domain identified by TMHMM2. ProfileScan hit to PS50321, Asparagine-rich region 23613541 Similar to Plasmodium falciparum Mal3p8.10 protein mal3p8.10 TR:Q9Y012 (EMBL:AL034560) (587 aa) fasta scores: E(): 5.4e-69, 40.278% id in 504 aa. Similarity with protein kinase domain STYkc found by SMART. N-terminal signal peptide. Similar to Plasmodium falciparum Pfc0060c, mal3p8.10 protein pfc0060c, mal3p8.10 SWALL:Q9Y012 (EMBL:AL034560) (587 aa) fasta scores: E(): 1.5e-68, 37.52% id in 589 aa, and to Plasmodium falciparum 3.8 protein 3.8 SWALL:Q25759 (EMBL:Z11832) (332 aa) fasta scores: E(): 1.3e-57, 47.72% id in 329 aa. Pfam match to entry PF00069 pkinase, Protein kinase domain, score 22.10, E-value 4.8e-05; ProfileScan hit to PS50011, Protein kinase domain profile. 23613542 2 transmembrane domains identified with TMHMM2. Pfam match to entry PF00069 pkinase, Protein kinase domain, score 24.20, E-value 1.3e-05; ProfileScan hit to PS50011, Protein kinase domain profile. 23613543 N-terminal signal peptide. Similar to Plasmodium falciparum Pfc0060c, mal3p8.10 protein pfc0060c, mal3p8.10 SWALL:Q9Y012 (EMBL:AL034560) (587 aa) fasta scores: E(): 6.6e-66, 41.92% id in 489 aa, and to Plasmodium falciparum 3.8 protein 3.8 SWALL:Q25759 (EMBL:Z11832) (332 aa) fasta scores: E(): 3.6e-53, 50.81% id in 307 aa. Pfam match to entry PF00069 pkinase, Protein kinase domain, score 20.60, E-value 0.00013; ProfileScan hit to PS50011, Protein kinase domain profile. 23613544 single transmembrane domain and N-terminal signal peptide 23613545 Similar to Plasmodium falciparum Pfc0060c, mal3p8.10 protein pfc0060c, mal3p8.10 SWALL:Q9Y012 (EMBL:AL034560) (587 aa) fasta scores: E(): 1.6e-64, 42.43% id in 476 aa, and to Plasmodium falciparum 3.8 protein 3.8 SWALL:Q25759 (EMBL:Z11832) (332 aa) fasta scores: E(): 1.9e-55, 49.67% id in 312 aa 23613546 With weak SMART hit (7.4e-04) to protein kinase STYKc domain. Similar to Plasmodium falciparum Mal3p8.10 protein mal3p8.10 TR:Q9Y012 (EMBL:AL034560) (587 aa) fasta scores: E(): 2e-66, 38.610% id in 518 aa 23613547 single transmembrane domain. Similar to Plasmodium falciparum Pfc0060c, mal3p8.10 protein pfc0060c, mal3p8.10 SWALL:Q9Y012 (EMBL:AL034560) (587 aa) fasta scores: E(): 5.3e-43, 36.13% id in 606 aa, and to Plasmodium falciparum 3.8 protein 3.8 SWALL:Q25759 (EMBL:Z11832) (332 aa) fasta scores: E(): 1.6e-41, 41.31% id in 397 aa. Pfam match to entry PF00069 pkinase, Protein kinase domain, score 15.50, E-value 0.0033; ProfileScan hit to PS50011, Protein kinase domain profile. 23613548 Hypothetical protein. With Glutamic acid-rich region in C-terminus and with single transmembrane motif and a coiled coil structure identified using HMMSmart. Single N-terminal transmembrane domain 23613549 Similar to Plasmodium falciparum sera antigen/papain-like protease with active ser pfb0340C TR:Q9TY95 (EMBL:AE001388) (997 aa) fasta scores: E(): 1.7e-116, 40.039% id in 1019 aa, and to Plasmodium falciparum serine-repeat antigen protein serA TR:Q9NIF4 (EMBL:AF214067) (995 aa) fasta scores: E(): 4.9e-116, 39.352% id in 1019 aa. match to PfaDd2|0108c3|1999.12.28|EST|UFla 1..312 blast score 607 percent identity 99 none. HMMPfam hit to PF00112, Papain family cysteine protease; HMMSmart hit to SM0645, Pept_C1, papain family cysteine protease; FPrintScan hit to PR00705, Papain cysteine protease (C1) family signature 23613550 Hypothetical protein with 2 transmembrane domains identified using SMART. With putative N-terminal signal peptide 23613551 Hypothetical protein, with single transmembrane domain identified using SMART 23613552 Similar to Drosophila melanogaster Cg11857 protein cg11857 TR:Q9VBU6 (EMBL:AE003751) (203 aa) fasta scores: E(): 1.8e-16, 42.541% id in 181 aa. With 3 transmembrane domains 23613553 Similar to Plasmodium falciparum putative Rab7 gtpase rab7 TR:Q9NFG0 (EMBL:AJ290938) (206 aa) fasta scores: E(): 2.4e-65, 97.647% id in 170 aa. With N-terminal signal sequence. Similar to Homo sapiens ras-related protein rab-7 rab7 SWALL:RAB7_HUMAN (SWALL:P51149) (207 aa) fasta scores: E(): 3.1e-40, 62.42% id in 173 aa. HMMPfam hit to PF00071, Ras family; HMMSmart hit to SM00010 23613554 Hypothetical asparagine-rich protein with 3 putative transmembrane domains. match to Pfa3D7|2352|2000.12.28|EST|UTokyo 8..80 blast score 145 percent identity 100 none. match to Pfa3D7|5984|2000.12.28|EST|UTokyo 151..250 blast score 198 percent identity 100 none. Very weakly similar to Plasmodium falciparum Pfc0425W protein pfc0425W TR:O77336 (EMBL:Z98547) (4550 aa) fasta scores: E(): 4.1e-29, 21.768% id in 3257 aa 23613555 Large protein with several pfam hits including DEAD, DUF19, Helicase C and OspEF like domains. Strong similarity with several helicases. Similar to Caenorhabditis elegans putative helicase C28h8.3 c28h8.3 SWALL:YP93_CAEEL (SWALL:Q09475) (1722 aa) fasta scores: E(): 9.8e-11, 26.88% id in 837 aa. HMMPfam hit to PF00270, DEAD/DEAH box helicase; HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain 23613556 Hypothetical asparagine-rich protein. match to Pfa3D7|5522|2000.12.28|EST|UTokyo 1..500 blast score 890 percent identity 97 none. No hit to HMMpfam; ProfileScan hit to PS50321, Asparagine-rich region; FPrintScan hit to PR00194, Tropomyosin signature 23613557 Hypothetical protein. Very weakly similar to Plasmodium falciparum hypothetical 118.9 kDa protein pfb0765W TR:O96246 (EMBL:AE001417) (980 aa) fasta scores: E(): 1.1e-08, 24.936% id in 778 aa 23613558 Similar to Plasmodium falciparum tubulin alpha chain SW:TBA_PLAFK (P14642) (453 aa) fasta scores: E(): 8.9e-191, 100.000% id in 453 aa. HMMPfam hit to PF00091, Tubulin/FtsZ family 23613559 Hypothetical protein with weak similarity (1.04e-03)to LCCL SMART domain. N-terminal signal peptide 23613560 Similar to Homo sapiens (Human), Mus musculus (Mouse), and 60S ribosomal protein l32 rpl32 SW:RL32_HUMAN (P02433) (134 aa) fasta scores: E(): 1.3e-27, 61.789% id in 123 aa. HMMPfam hit to PF01655, Ribosomal protein L32; BlastProDom hit to PD003823 23613561 Hypothetical protein with RabGAP/TBC domain. HMMPfam hit to PF00566, TBC domain; HMMSmart hit to SM00164, Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs. 23613562 Similar to Arabidopsis thaliana epsilon-adaptin, putative f27m3_7 TR:Q9C6W3 (EMBL:AC074360) (933 aa) fasta scores: E(): 1.5e-58, 46.835% id in 474 aa, and to Homo sapiens adapter-related protein complex 4 epsilon 1 subunit ap4e1 SW:A4E1_HUMAN (Q9UPM8) (1137 aa) fasta scores: E(): 8.8e-49, 41.124% id in 445 aa. HMMPfam hit to PF01602, Adaptin N terminal region 23613563 Hypothetical protein with putative N-terminal transmembrane domain and signal /peptide and interpro hit to shal voltage-gated K+ channel family signature. FPrintScan hit to PR01497, Shal voltage-gated K+ channel family signature 23613564 Hypothetical protein with 8 putative transmembrane domains 23613565 With single N-terminal transmembrane domain. Similar to Arabidopsis thaliana probable microsomal signal peptidase 22 kDa subunit at3g05230 or t12h1.20 SWALL:Q9MA96 (EMBL:AF057144) (167 aa) fasta scores: E(): 1.6e-10, 35.22% id in 176 aa, and to Gallus gallus microsomal signal peptidase 23 kDa subunit spc22 SWALL:SP22_CHICK (SWALL:P28687) (180 aa) fasta scores: E(): 5.8e-08, 26.4% id in 178 aa 23613566 Similar to Caenorhabditis elegans probable prefoldin subunit 4 b0035.4 SW:PFD4_CAEEL (Q17435) (126 aa) fasta scores: E(): 1.3e-05, 32.479% id in 117 aa 23613567 Hypothetical protein with C-terminal pfam hits with UCH1 and UCH2 domains. match to Pfa3D7|2687|2000.12.28|EST|UTokyo 48..151 blast score 206 percent identity 100 none. match to Pfa3D7|2687|2000.12.28|EST|UTokyo 385..500 blast score 230 percent identity 100 none. HMMPfam hit to PF00443, Ubiquitin carboxyl-terminal hydrolase family 2 23613568 Conserved hypothetical protein with well conserved BHL domain (Bacterial Histone /Domain) peptide sequence.. N-terminal signal peptide. Pfam match to PF00216, Bacterial DNA-binding protein, E()=3.50e-17 23613569 Similar to Cryptosporidium parvum replication protein a large subunit rpa1 TR:Q9Y1I9 (EMBL:AF132307) (473 aa) fasta scores: E(): 4.3e-22, 23.614% id in 487 aa. match to Pfa3D7|4094|2000.12.28|EST|UTokyo 199..500 blast score 511 percent identity 96 none. contains pfam hit of putative tRNA_ant domain 23613570 Hypothetical protein with E1-E2_ATPase and Hydrolase pfam hits, and 6 putative transmembrane domains. match to Pfa3D7|2258|2000.12.28|EST|UTokyo 1..500 blast score 942 percent identity 98 none. HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase; HMMPfam hit to PF00122, E1-E2 ATPase 23613572 Hypothetical glycine-rich protein with 4 transmembrane motifs. Blast hits with putative nucleoporins at the N-terminal segment 23613573 Significant pfam hit (4.3e-23) to mito_carr domain. Similar to Onchocerca gibsoni mitochondrial solute carrier SWALL:Q94634 (EMBL:U45997) blast scores: E(): 3e-12, score: 76 31% id, and to Arabidopsis thaliana putative mitochondrial carrier protein at2g30160 SWALL:O64731 (EMBL:AC004165) blast scores: E(): 2e-10, score: 70 30% id. MMPfam hit to PF00153, Mitochondrial carrier protein 23613574 Hypothetical protein. HMMPfam hit to PF03028 23613575 Similar to Plasmodium yoelii high molecular weight rhoptry protein 3 pyrhoph3 /TR:Q9GNF1 (EMBL:AB044564) (882 aa) fasta scores: E(): 4.5e-129, 42.825% id in 878 aa. match to PfaDd2|2044c3|1999.12.28|EST|UFla 1..309 blast score 605 percent identity 100 none. With N-terminal signal peptide. match to PfaDd2|1344c3|1999.12.28|EST|UFla 42..394 blast score 692 percent identity 100 none 23613576 Hypothetical protein with 3 predicted transmembrane domains 23613577 Hypothetical protein with several WD40 domain pfam hits. HMMPfam hit to PF00400, WD domain, G-beta repeat; HMMSmart hit to SM00320, WD40 repeats 23613578 Thre is a potential exon-like sequence present between the exon 4 and exon 5 in the current gene model but not appropriate splice donor and acceptor site was found. match to PfaDd2|0122c3|1999.12.28|EST|UFla 126..198 blast score 145 percent identity 100 none. match to PfaDd2|0122c3|1999.12.28|EST|UFla 17..87 blast score 141 percent identity 100 none. Similar to Schizosaccharomyces pombe hypothetical 31.9 kDa protein c3b9.06c in chromosome ii spbc3b9.06C SWALL:O43035 (EMBL:AL022070) (275 aa) fasta scores: E(): 3.6e-12, 27.67% id in 271 aa, and to Saccharomyces cerevisiae autophagocytosis protein aut1 aut1 or ynr007c or n2040 SWALL:AUT1_YEAST (SWALL:P40344) (310 aa) fasta scores: E(): 1.5e-08, 27.18% id in 298 aa, and to Arabidopsis thaliana autophagocytosis protein aut1-like SWALL:Q9FKG9 (EMBL:AB012239) (334 aa) fasta scores: E(): 7.3e-07, 29.43% id in 299 aa 23613579 Hypothetical protein. HMMSmart hit to SM00509, Domain in the N-terminus of transcription elongation factor S-II (and elsewhere) 23613580 Similar to Arabidopsis thaliana F18b13.7 protein f18b13.7 TR:Q9SSD5 (EMBL:AC009322) (920 aa) fasta scores: E(): 7.4e-81, 37.593% id in 939 aa. match to Pfa3D7|6313|2000.12.28|EST|UTokyo 37..500 blast score 835 percent identity 97 none. Similar to Homo sapiens coatomer beta' subunit copb2 SWALL:AAH00326 (EMBL:X70476) (906 aa) fasta scores: E(): 7.1e-80, 38.28% id in 888 aa. HMMPfam hit to PF00400, WD domain, G-beta repeat; HMMSmart hit to SM00320, WD40 repeats 23613581 Hypothetical protein with putative single trnsmembrane domain. match to PfaDd2|0441c3|1999.12.28|EST|UFla 15..277 blast score 502 percent identity 99 none. pfamB (PB054968) match (7.4e-09) to RNB-like domain 23613582 Similar to Dictyostelium discoideum developmental protein Dg1118 dg1118 TR:O96552 (EMBL:AF081802) (192 aa) fasta scores: E(): 4.6e-16, 33.511% id in 188 aa 23613583 Hypothetical protein with putative N-terminal transmembrane domain 23613584 Hypothetical protein. HMMPfam hit to PF00773, RNB-like protein 23613585 Hypothetical protein 23613586 Hypothetical protein. last exon doesn't end with a stop codon 23613587 Hypothetical protein. match to PfaDd2|0108c3|1999.12.28|EST|UFla 1..312 blast score 607 percent identity 99 none. HMMPfam hit to PF00642, Zinc finger C-x8-C-x5-C-x3-H type (and similar); HMMSmart hit to SM00356, zinc finger. CCCH zinc finger proteins are often involved in cell cycle or growth phase regulation 23613588 Hypothetical protein. HMMPfam hit to PF00560, Leucine Rich Repeat 23613590 Hypothetical protein with 2 predicted transmembrane domains; 2 potential downstrean exons possible 23613591 Hypothetical protein with TBC / Rab-GAP domain. HMMPfam hit to PF00566, TBC domain; HMMSmart hit to SM00164, Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs 23613592 Hypothetical protein 23613593 C-terminal half of protein is similar to prokaryotic ATP-dependent heat shock proteins. Similar to Rhizobium loti heat shock protein, ATP-dependent hsl protease ATP-binding subunit, hslu mll5004 SWALL:Q98CU1 (EMBL:AP003005) (443 aa) fasta scores: E(): 8.5e-54, 46.69% id in 439 aa, and to Escherichia coli, and ATP-dependent hsl protease ATP-binding subunit hslu hslu or htpi or b3931 or z5478 or ecs4858 SWALL:HSLU_ECOLI (SWALL:P32168) (443 aa) fasta scores: E(): 2.1e-51, 46.56% id in 451 aa. No HMMPfam hit; HMMSmart hit to SM00382, ATPases associated with a variety of cellular activities 23613594 Hypothetical protein 23613595 Hypothetical protein. Profilescan hit to PS50296, homology region to translational fideity controller sui1 23613596 Similar to Homo sapiens ki nuclear autoantigen TR:Q12920 (EMBL:U11292) (267 aa) fasta scores: E(): 1.5e-21, 32.453% id in 265 aa. HMMPfam hit to PF02252, Proteasome activator pa28 beta subunit 23613597 Ribosomal protein L35 23613598 Similar to Lycopersicon esculentum peptide deformylase-like protein TR:Q9FV54 (EMBL:AF250958) (279 aa) fasta scores: E(): 3.8e-25, 48.214% id in 168 aa. HMMPfam hit to PF01327, Polypeptide deformylase 23613599 Similarity to bifunctional nucleases. Weak Pfam hit to PF02265, S1/P1 Nuclease E()=e-4; nuclease domain and a single N-terminal transmembrane domain 23613600 Hypothetical protein, with 6 putative transmembrane domains, detected by TMHMM2.0 23613601 Hypothetical protein with blast hit (1.00e-09) with stykc domain 23613602 Hypothetical protein with 6 putative transmembrane segments 23613603 Hypothetical protein with single putative transmembrane domain 23613604 Hypothetical protein. Could be consisting of 2 or more separate protein translation units 23613605 Similarity with ribosomal RNA methyltransferases, Pfam hit with PF01728, Ftsj-like methyl transferase. Similar to Caenorhabditis elegans putative ribosomal RNA methyltransferase R74.7 r74.7 SWALL:RRM2_CAEEL (SWALL:Q22031) (337 aa) fasta scores: E(): 2.4e-13, 30.07% id in 419 aa, and to Drosophila melanogaster putative ribosomal RNA methyltransferase Cg5220 cg5220 SWALL:RRM1_DROME (SWALL:Q9VEP1) (302 aa) fasta scores: E(): 1.8e-12, 31.77% id in 384 aa. HMMPfam hit to FtsJ-like methyltransferase 23613606 Similar to Saccharomyces cerevisiae pseudouridylate synthase 3 pus3 or deg1 or yfl001W SWALL:PUS3_YEAST (SWALL:P31115) (442 aa) fasta scores: E(): 7.5e-17, 37.25% id in 255 aa, and to Arabidopsis thaliana putative pseudouridine synthase f12g12.3 SWALL:Q9C5K6 (EMBL:AF360187) (446 aa) fasta scores: E(): 1e-11, 31.6% id in 250 aa. HMMPfam hit to PF01416, tRNA pseudouridine synthase 23613607 Hypothetical protein with 4 putative transmembrane domains. Similar to Plasmodium falciparum adenine nucleotide translocase SWALL:Q25692 (EMBL:U04335) (301 aa) fasta scores: E(): 7.5e-07, 25.34% id in 217 aa. HMMPfam hit to PF00153, Mitochondrial carrier protein 23613608 Hypothetical protein with asparagine-rich domain 23613609 Hypothetical protein with N-terminal asparagine-rich domain 23613610 Hypothetical protein with 4 putative transmembrane doimains, with 2 asparagine-rich domains 23613611 Hypothetical Protein with N-terminal signal peptide 23613612 Pfam hit of DUF122 domain (2.5e-05) / shal voltage-gated K+ channel family signature at C-terminus, thought to be related to programmed cell death. Moderately similar (mostly in the c-terminal region) to Drosophila melanogaster cg13072 protein pdcd-5 or cg13072 TR:Q9VUZ8 (EMBL:AE003528) (133 aa) fasta scores: E(): 1e-05, 37.634% id in 93 aa. Similar to Mus musculus programed cell death protein 5 pdcd5 or tfar19 SWALL:PCD5_MOUSE (SWALL:P56812) (126 aa) fasta scores: E(): 0.00017, 35.86% id in 92 aa, and to Arabidopsis thaliana F1n18.11 protein f1n18.11 SWALL:Q9FXG0 (EMBL:AC008030) (129 aa) fasta scores: E(): 9.7e-08, 42.85% id in 84 aa, and to Drosophila melanogaster cg13072 protein pdcd-5 or cg13072 SWALL:Q9VUZ8 (EMBL:AE003528) (133 aa) fasta scores: E(): 1.1e-05, 37.63% id in 93 aa. No HMMPfam hit; BlastProDom hit to PD008148; FPrintScan hit to PR01497, Shal voltage-gated K+ channel family signature 23613613 Similar to Arabidopsis thaliana Xrn3 xrn3 TR:Q9FQ03 (EMBL:AF286719) (1020 aa) fasta scores: E(): 5.3e-34, 32.930% id in 908 aa 23613614 Hypothetical proline rich protein. Distantly similar to Vigna unguiculata extensin class 1 protein precursor ext26G /TR:Q41707 (EMBL:X91836) (489 aa) fasta scores: E(): 4.3e-19, 30.657% id in 411 aa. match to PfaDd2|1724c3|1999.12.28|EST|UFla 1..386 blast score 749 percent identity 99 none 23613615 Hypothetical protein. match to Pfa3D7|6768|2000.12.28|EST|UTokyo 380..500 blast score 234 percent identity 99 none 23613616 Asparagine-rich protein. match to Pfa3D7|3651|2000.12.28|EST|UTokyo 1..266 blast score 498 percent identity 98 none. Similar to Babesia microti seroreactive antigen bmn1-9b SWALL:Q9NIN1 (EMBL:AF206252) (428 aa) fasta scores: E(): 4.5e-26, 27.94% id in 408 aa, and to Dictyostelium discoideum homeobox-containing protein hbx-2 SWALL:O43989 (EMBL:AF036171) (534 aa) fasta scores: E(): 4.8e-24, 34.07% id in 405 aa. HMMPfam hit to PF00498, FHA domain (Forkhead associoated domain) 23613617 Similar to Homo sapiens small nuclear ribonucleoprotein sm d3 snrpd3 SW:SMD3_HUMAN (P43331) (126 aa) fasta scores: E(): 1.2e-08, 41.322% id in 121 aa. HMMPfam hit to PF01423,small nuclear ribonucleoprotein (Sm protein) 23613618 Similar to Schizosaccharomyces pombe putative helicase spcc550.03C TR:O59801 (EMBL:AL023592) (1213 aa) fasta scores: E(): 1.5e-38, 30.554% id in 1355 aa. HMMPfam hit to PF00270, DEAD/DEAH box helicase; HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain 23613619 Hypothetical protein with HMMSmart hit to SET-domain of transcriptional regulators. No HMMPfam hit; HMMSmart hit to SM00317, SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain 23613620 Hypothetical protein, with FPrintScan hit to bacterial rhodopsin domain 23613621 Hypothetical protein 23613622 Hypothetical protein with N-terminal signal peptide sequence and putative c-terminal transmembrane domain. match to Pfa3D7|2554|2000.12.28|EST|UTokyo 334..470 blast score 266 percent identity 99 none 23613623 Hypothetical protein with weak hit to AIR synthase C-terminal domain. HMMPfam hit to PF02769, AIR synthase related protein, C-terminal domain 23613624 Hypothetical protein. HMMPfam hit to PF00533, BRCA1 C Terminus (BRCT) domain; HMMSmart hit to SM00292, breast cancer carboxy-terminal domain 23613625 Similar to Schizosaccharomyces pombe hypothetical 22.7 kDa protein c13g1.11 in chromosome ii spbc13g1.11 TR:O60073 (EMBL:AL022600) (197 aa) fasta scores: E(): 1.6e-15, 28.000% id in 200 aa, and to Candida albicans probable snare protein ca49c10.18 TR:O94032 (EMBL:AL033497) (200 aa) fasta scores: E(): 1e-14, 30.435% id in 184 aa. ScanProsite hit to putative prenyl group binding site 23613626 Hypothetical protein. Similar to Saccharomyces cerevisiae actin-like protein arp3 arp3 or act4 or yjr065c or j1760 SWALL:ARP3_YEAST (SWALL:P47117) (449 aa) fasta scores: E(): 3.5e-06, 26.11% id in 268 aa, and to Gallus gallus actin-like protein 2 actr2 or arp2 SWALL:ARP2_CHICK (SWALL:P53488) (394 aa) fasta scores: E(): 0.00034, 24.09% id in 386 aa. HMMPfam hit to PF00022, Actin;HMMSmart hit to SM00268, Actin 23613627 Similar to Arabidopsis thaliana nucleotide-binding protein TR:Q9FI52 (EMBL:AB017063) (317 aa) fasta scores: E(): 3.2e-44, 47.440% id in 293 aa, and to Schizosaccharomyces pombe hypothetical 34.3 kDa protein c637.08 in chromosome i spac637.08 TR:O94442 (EMBL:AL034583) (317 aa) fasta scores: E(): 2.7e-43, 45.016% id in 311 aa, and to Leishmania major mrp-family nucleotide-binding protein l8329.08 TR:Q9GRN9 (EMBL:AL446004) (327 aa) fasta scores: E(): 7.9e-35, 38.941% id in 321 aa and similarity to several nucleotide binding proteins. With N-terminal signal sequence and single N-terminal transmembrane domains.. Putative nucleotide binding protein with Interpro hits to ATP/GTP-binding proteins (P-loop) and Mrp family signature 23613628 Similar to Mus musculus DNA primase large subunit prim2 SW:PRI2_MOUSE (P33610) (505 aa) fasta scores: E(): 1.1e-31, 30.943% id in 488 aa. Similarity to several DNA-primases, large subunit but no significant Interpro hit 23613629 Weakly similar to Arabidopsis thaliana putative phosphatidylinositol-glycan-class c f19i3.21 TR:O64761 (EMBL:AC004238) (303 aa) fasta scores: E(): 0.00044, 21.352% id in 281 aa. With 5 putative transmembrane domains. No significant hit in Interpro search. match to Pfa3D7|4122|2000.12.28|EST|UTokyo 363..434 blast score 143 percent identity 100 none 23613630 Hypothetical protein. Interpro hits to Immunoglobulin and MHC compolex domain and also to shal voltage-gated K+ channel 23613631 Hypothetical protein 23613632 Hypothetical protein with 7 putative transmembrane domains in the C-terminal half of the protein. HMMPfam hit to PF00051, Kringle domain; HMMSmart hit to SM00130, Kringle domain 23613633 Hypothetical protein 23613634 Hypothetical protein. Very weak similarity to Borrelia turicatae repeat motif protein Rept3 rept3 TR:Q9RGH8 (EMBL:AF128446) (207 aa) fasta scores: E(): 0.24, 25.455% id in 165 aa 23613635 Asperagine-rich hypothetical protein 23613636 Similarity to Thermotoga maritima GTP-binding protein lepa or tm1623 SW:LEPA_THEMA (Q9X1V8) (621 aa) fasta scores: E(): 4.2e-37, 30.268% id in 859 aa. Similarity with several LepA like GTP-binding proteins with a non-conserved big chunk of amino acids in the middle of the protein, also with N-terminal signal sequence. Similarity starts at about 220 amino acid downstream of predicted protein. Check again for possible >1 ORF in this region. match to Pfa3D7|6424|2000.12.28|EST|UTokyo 1..499 blast score 959 percent identity 99 none. contains KCDENGQV repeat array. PF00009 (9.7e-55) GTP-binding elongation factor Tu family, other Interpro hits include RasGTPase superfamily signature and ATP/GTP binding site motif A (P-loop) 23613637 Hypothetical protein with single C-terminal transmembrane domain 23613638 Hypothetical Asparagine-rich protein with N-terminal signal sequence 23613639 Hypothetical protein with 3 transmembrane domains. match to Pfa3D7|4758|2000.12.28|EST|UTokyo 441..500 blast score 111 percent identity 98 none 23613640 Hypothetical protein 23613641 Hypothetical protein with 6 putative transmembrane domains 23613642 Hypothetical protein. match to PfaDd2|2169c3|1999.12.28|EST|UFla 177..236 blast score 119 percent identity 100 none 23613643 Conserved hypothetical protein. Moderately similar to Arabidopsis thaliana hypothetical 50.3 kDa protein TR:Q9C5E0 (EMBL:AF360310) (447 aa) fasta scores: E(): 2.3e-08, 28.009% id in 457 aa with gaps 23613644 Hypothetical protein with single N-terminal transmembrane domain. weak hit to SAP domain, also HMMSmart hit to DNA binding motif (bihelical) predicted to function chromosomal organisation 23613645 Hypothetical protein 23613646 Hypothetical protein 23613647 Hypothetical protein 23613648 Similar to Arabidopsis thaliana 26s proteasome regulatory subunit s12, putative, 66155-68483 f11b9.19 TR:Q9C774 (EMBL:AC073395) (310 aa) fasta scores: E(): 6.9e-44, 48.110% id in 291 aa. Mov34/MPN/PAD-1 family 23613649 Hypothetical protein 23613650 Hypothetical protein 23613651 Identical to Plasmodium falciparum translation elongation factor 1 beta ef-1B TR:Q9NI00 (EMBL:AF217234) (276 aa) fasta scores: E(): 2e-89, 100.000% id in 276 aa. EF-1 guanine nucleotide exchange domain 23613653 Hypothetical protein 23613654 With pfam hit of Abi domain (5.5e-10), with 6 putative transmembrane domains and N-terminal signal sequence. CAAX family of proteases, Interpro hit to Abortive Infection Protein (Abi) 23613655 Hypothetical protein 23613656 Conserved hypothetical protein. Similar to Plasmodium falciparum hypothetical 73.3 kDa protein mal4p2.18 TR:Q9U0K4 (EMBL:AL035475) (622 aa) fasta scores: E(): 8.3e-15, 25.301% id in 581 aa. With N-terminal signal peptide sequence 23613657 Hypothetical protein 23613658 Hypothetical protein with N-terminal signal peptide. Weak hit (9.4e-03)to Arginyl T-RNA synthetase 23613659 With N-terminal similarity to a DRAP deaminase of S. cerevisiae and N-terminal signal peptide sequence. RNA pseudouridylate synthase, other Interpro hits include bipartite nuclear localisation signal and shal voltage-gated K+ channel 23613660 Hypothetical protein 23613661 Similar to Borrelia burgdorferi 1-acyl-sn-glycerol-3-phosphate acyltransferase plsc or bb0037 SWALL:PLSC_BORBU (SWALL:Q59188) (250 aa) fasta scores: E(): 3.3e-05, 28.03% id in 214 aa, and to Nicotiana tabacum Jd1 jd1 SWALL:Q9FPM8 (EMBL:AF316320) (407 aa) fasta scores: E(): 6.1e-09, 31.01% id in 158 aa. Phospholipid and glycerol acyl transferase, HMMSmart hit phosphate acyl transferase (PlsC) domain 23613662 N-terminal signal peptide. Met-10+ like protein domain (8.5e-31) 23613663 Hypothetical protein with several C-terminal conserved residues to Arabidopsis thaliana F3o9.32 protein f3o9.32 TR:Q9SA50 (EMBL:AC006341) (325 aa) fasta scores: E(): 5.6e-08, 30.744% id in 309 aa 23613665 Similar to Caenorhabditis elegans Y54g11a.11 protein y54g11a.11 TR:Q9XVZ8 (EMBL:AL034488) (84 aa) fasta scores: E(): 1.6e-10, 42.683% id in 82 aa 23613666 Hypothetical protein with 11 putative transmembrane domains 23613667 Hypothetical protein 23613668 Asparagine-rich Hypothetical protein 23613669 Similar to Solanum tuberosum putative external rotenone-insensitive NADH dehydrogenase ndb1 TR:Q9ST62 (EMBL:AJ245862) (577 aa) fasta scores: E(): 4.2e-44, 30.597% id in 536 aa, and to Arabidopsis thaliana putative NADH-ubiquinone oxireductase at2g20800 TR:Q9SKT7 (EMBL:AC006234) (582 aa) fasta scores: E(): 5.6e-44, 33.215% id in 563 aa. HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase, includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases 23613670 Similar to Dictyostelium discoideum putative e2 enzyme Ubc9 ubc9 TR:Q9NGP4 (EMBL:AF246690) (159 aa) fasta scores: E(): 3.4e-39, 61.935% id in 155 aa, and to Schizosaccharomyces pombe ubiquitin-conjugating enzyme e2-18 kDa hus5 or spac30d11.13 SW:UBC3_SCHPO (P40984) (157 aa) fasta scores: E(): 6.2e-39, 62.821% id in 156 aa 23613671 Hypothetical protein. match to Pfa3D7|6076|2000.12.28|EST|UTokyo 21..440 blast score 773 percent identity 98 none 23613672 Hypothetical protein 23613673 Similar to Chlamydia pneumoniae fructose-6-p phosphotransferase pfka_2 or cpn0208 or cp0559 TR:Q9Z8X6 (EMBL:AE001607) (550 aa) fasta scores: E(): 2.2e-70, 41.142% id in 508 aa. The similarity exists upto 550 amino acids and there is no similarity in the last 700 amino acids. match to Pfa3D7|1106|2000.12.28|EST|UTokyo 56..500 blast score 866 percent identity 100 none. HMMPfam hit to PF00365, Phosphofructokinase 23613674 Hypothetical asperagine-rich protein 23613675 Hypothetical protein 23613676 Hypothetical protein 23613677 putative glycolipid transfer protein. Moderately similar to Drosophila melanogaster Cg6299 protein cg6299 TR:Q9VXV1 (EMBL:AE003499) (205 aa) fasta scores: E(): 0.00083, 27.041% id in 196 aa 23613678 Hypothetical protein 23613679 Hypothetical protein with 11 putative transmembrane domains and asparagine-rich C terminal. HMMPfam hit to PF00083, Sugar (and other) transporter 23613680 Putative thioredoxin. ProfileScan hit to PS50223, Thioredoxin-domain (does not find all).. Similarity to Plasmodium falciparum thioredoxin trX TR:Q9NFK9 (EMBL:AJ277839) (104 aa) fasta scores: E(): 9.3e-06, 29.670% id in 91 aa. Similar to Gallus gallus thioredoxin txN SWALL:THIO_CHICK (SWALL:P08629) (104 aa) fasta scores: E(): 1.6e-05, 28.57% id in 105 aa, and to Ophiophagus hannah thioredoxin txN SWALL:Q98TX1 (EMBL:AF321769) (105 aa) fasta scores: E(): 1.3e-08, 36.44% id in 107 aa 23613681 Hypothetical protein with single N-terminal transmembrane domain 23613682 Hypothetical protein 23613683 Hypothetical protein. No pfam hit, HMMSmart hit to SM00184, Ring finger 23613684 Hypothetical protein. No pfam hit, ScanProsite hit to bacterial rhodopsin 23613685 Similar to Drosophila melanogaster Cg9643 protein cg9643 TR:Q9VQJ8 (EMBL:AE003581) (219 aa) fasta scores: E(): 9.7e-14, 30.531% id in 226 aa. No pfam match, ProfileScan hit to PS50193, SAM (and some other nucleotide) binding motif) 23613686 Putative RNA-binding protein. Similarity to several nuclear RNA-binding protein. HMMPfam hit to PF00076, RNA recognition motif (eg. RRM, RBD, or RNP domain), HMMSmart, ScanProsite and ProfileScan hit to RNA recognition motif 23613687 Asparagine-rich hypothetical protein 23613688 Hypothetical protein. match to Pfa3D7|7040|2000.12.28|EST|UTokyo 304..500 blast score 391 percent identity 100 none 23613689 Hypothetical protein with putative excision DNA repair function or DNA glycosylase function. Similar to Rattus norvegicus N-glycosylase/DNA lyase (includes: 8-oxoguanine dna glycosylase ogg1 or mmh or ogh1 SWALL:OGG1_RAT (SWALL:O70249) (345 aa) fasta scores: E(): 2.2e-06, 35.2% id in 125 aa. HMMPfam hit to PF00730 (HhH-GPD superfamily base excision DNA repair protein), HMMSmart hit to SM00478, endonuclease III 23613690 Hypothetical protein with 5 putative transmembrane domains 23613691 Hypothetical protein with 4 putative transmembrane domains 23613692 Hypothetical protein. Weakly similar to Plasmodium falciparum Pfc0770C protein pfc0770C TR:O77382 (EMBL:Z98551) (1619 aa) fasta scores: E(): 3.7e-09, 21.490% id in 1396 aa 23613693 Hypothetical protein 23613694 Putative ATP-dependant RNA helicase protein. Similar to Arabidopsis thaliana ATP-dependent RNA helicase-like protein t12c14_10 TR:Q9LZQ9 (EMBL:AL162507) (726 aa) fasta scores: E(): 3e-153, 61.472% id in 693 aa, and to Schizosaccharomyces pombe putative pre-mrna splicing factor ATP-dependent RNA helicase Spbc16h5.10C spbc16h5.10C SW:DD15_SCHPO (O42945) (735 aa) fasta scores: E(): 3.3e-142, 56.667% id in 720 aa. HMMPfam hit to PF00271,Helicase conserved C-terminal domain; HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain; HMMSmart hit to SM00490, helicase superfamily c-terminal domain; ProfileScan hit to PS50136, DNA/RNA helicase domain (DEAD/DEAH box). 23613695 Similar to Arabidopsis thaliana emb|cab92117.1 TR:Q9FMR4 (EMBL:AB007651) (291 aa) fasta scores: E(): 7.9e-32, 42.342% id in 333 aa. HMMPfam hit to PF03029; ScanProsite hit to PS00017; Interpro hit to ATP/GTP binding site motif A (p-loop) 23613696 Hypothetical protein 23613697 match to Pfa3D7|6504|2000.12.28|EST|UTokyo 39..500 blast score 908 percent identity 100 none. Similar to Plasmodium falciparum heat shock protein pfgrP SWALL:Q07615 (EMBL:X69121) (652 aa) fasta scores: E(): 4.8e-217, 99.38% id in 652 aa 23613698 Hypothetical protein with 2 transmembrane domains with similarity to several purple acid phosphatases. With weak similarity to Arabidopsis thaliana putative purple acid phosphatase at2g01890 TR:Q9SIS5 (EMBL:AC007069) (351 aa) fasta scores: E(): 1.7e-09, 28.197% id in 305 aa. HMMPfam hit to PF02227, Purple acid phosphatase; ScanProsite hit to PS00017, PS00030 23613699 Similar to Schizosaccharomyces pombe hypothetical 16.3 kDa heme-binding protein spcc330.03C TR:O74875 (EMBL:AL031603) (145 aa) fasta scores: E(): 3.3e-08, 52.239% id in 67 aa. Conserved hypothetical protein with putative heme binding function. HMMpfam match (3.0e-06) to Heme_1 domain, PF00173; Interpro hit to IPR001199 23613700 Similar to Mycoplasma capricolum 50s ribosomal protein l3 rplC SW:RL3_MYCCA (P10134) (223 aa) fasta scores: E(): 7.9e-25, 40.704% id in 199 aa, and to Bacillus subtilis 50s ribosomal protein l3 rplC SW:RL3_BACSU (P42920) (209 aa) fasta scores: E(): 4.2e-22, 40.865% id in 208 aa. Similar to Mycoplasma capricolum 50s ribosomal protein l3 rplC SWALL:RL3_MYCCA (SWALL:P10134) blast scores: E(): 1e-35, score: 376 40% id, and to Odontella sinensis chloroplast 50s ribosomal protein l3 rpl3 SWALL:RK3_ODOSI (SWALL:P49569) blast scores: E(): 9e-31, score: 335 38% id. HMMPfam hit to PF00297, Ribosomal protein L3; ScanProsite hit to PS00474 23613701 Conserved hypothetical protein. Similar to Schizosaccharomyces pombe hypothetical 33.3 kDa protein c4c3.07 in chromosome ii spbc4c3.07 TR:O43060 (EMBL:AL021730) (302 aa) fasta scores: E(): 7.7e-18, 30.847% id in 295 aa. HMMPfam hit to PF01398, Mov34/MPN/PAD-1 family;HMMSmart hit to SM00232, JAB/MPN domain; BlastProDom hit to PD005425 23613702 Hypothetical protein. With 3 putative transmembrane domains, very weak similarity to 1 EGF-like domain identified by HMMSmart and with N-terminal signal peptide. last exon doesn't end with a stop codon. last exon doesn't end with a stop codon 23613703 Hypothetical phenylalanine-rich protein with 3 putative transmembrane domains 23613704 Putative DNA helicase. Moderately similar to Arabidopsis thaliana DNA helicase recql3 TR:Q9FT72 (EMBL:AJ404472) (713 aa) fasta scores: E(): 1.7e-22, 30.563% id in 710 aa. Moderately similar to Homo sapiens ATP-dependent DNA helicase q5 recql5 SW:RCQ5_HUMAN (O94762) (410 aa) fasta scores: E(): 1.4e-17, 34.491% id in 403 aa and similarity with several other DNA helicases. HMMPfam hit to PF00270, DEAD/DEAH box helicase; HMMPfam hit to PF00271, Helicase conserved C-terminal domain;HMMSmart hit to SM00487, DEAD-like helicases superfamily, catalytic domain; FPrintScan hit to PR01497, Shal voltage-gated K+ channel family signature 23613705 Hypothetical protein. Weakly similar to Plasmodium reichenowi starp antigen precursor TR:Q26109 (EMBL:Z30339) (655 aa) fasta scores: E(): 8e-14, 23.577% id in 615 aa. Asperagine-rich hypothetical protein 23613706 Hypothetical protein with 2 putative transmembrane domains. HMMPfam hit to PF01207, Uncharacterized protein family UPF0034 23613707 Plasmodium falciparum gamma-glutamylcysteine synthetase gamma-gcS TR:Q9UB86 (EMBL:AJ007863) (1063 aa) fasta scores: E(): 0, 99.341% id in 1063 aa. HMMPfam hit to PF03074 23613708 Plasmodium falciparum nucleosome assembly protein b7 TR:Q9Y010 (EMBL:AJ238237) (269 aa) fasta scores: E(): 2.5e-94, 100.000% id in 269 aa 23613709 putative DNAJ-like protein with N-terminal signal sequence. HMMPfam hit to PF00226, DnaJ domain; HMMSmart hit to SM00271, DnaJ molecular chaperone homology domain; ScanProsite hit to PS00636, PS00636 Confirmed by InterPro eMOTIF pattern match. 23613710 Hypothetical protein 23613711 Hypothetical protein. Weakly similar to Caenorhabditis elegans hypothetical protein F29b9.5 f29b9.5 TR:AAK67231 (EMBL:U70849) (179 aa) fasta scores: E(): 2.8e-05, 32.800% id in 125 aa 23613712 single putative transmembrane domain. match to Pfa3D7|7250|2000.12.28|EST|UTokyo 1..480 blast score 842 percent identity 96 none. Similar to Homo sapiens protein disulfide isomerase a4 precursor pdia4 or erp72 or erp70 SWALL:PDA4_HUMAN (SWALL:P13667) (645 aa) fasta scores: E(): 1.2e-09, 23.18% id in 427 aa, and to Drosophila melanogaster protein disulfide isomerase precursor pdi or cg6988 SWALL:PDI_DROME (SWALL:P54399) (496 aa) fasta scores: E(): 3.3e-08, 20.69% id in 517 aa. No pfam hit; ProfileScan hit to PS50223, Thioredoxin-domain. 23613713 Putative suger transporter with 11 putative transmembrane domains. Similar to Plasmodium falciparum hexose transporter 1 ht1 or pfb0210C TR:O97467 (EMBL:AJ131457) (504 aa) fasta scores: E(): 1.2e-20, 24.066% id in 482 aa, and to Schizosaccharomyces pombe myo-inositol transporter 2 itr2 or spac20g8.03 SW:ITR2_SCHPO (P87110) (557 aa) fasta scores: E(): 1.3e-06, 22.705% id in 414 aa. HMMPfam hit to PF00083, Sugar (and other)transporter 23613714 Putative dolichyl-di-phosphooligosaccharide-protein with 2 putative transmembrane domains and N-terminal signal peptide. Moderately similar to Arabidopsis thaliana dolichyl-di-phosphooligosaccharide-protein glycotransferase TR:Q9LVR2 (EMBL:AB018119) (442 aa) fasta scores: E(): 2.2e-08, 22.118% id in 425 aa and several other such enzymes from other organisms. No pfam match; FPrintScan hit to PR01497, Shal voltage-gated K+ channel family signature 23613715 Similar to Homo sapiens proline synthetase co-transcribed bacterial homolog protein prosC SWALL:POSC_HUMAN (SWALL:O94903) (275 aa) fasta scores: E(): 1.9e-05, 31.04% id in 248 aa, and to Arabidopsis thaliana putative proline synthetase associated protein f10m23.200 or at4g26860 SWALL:Q9SZ26 (EMBL:AL035440) (262 aa) fasta scores: E(): 1.9e-10, 32.6% id in 230 aa. HMMPfam hit to PF01168, uncharacterized protein family UPF0001 23613716 Hypothetical protein. match to PfaDd2|0368c3|1999.12.28|EST|UFla 42..105 blast score 127 percent identity 100 none. No pfam match; FPrintScan hit to PR01497, Shal voltage-gated K+ channel family signature 23613717 Hypothetical protein. match to Pfa3D7|3263|2000.12.28|EST|UTokyo 48..424 blast score 660 percent identity 97 none. match to Pfa3D7|3493|2000.12.28|EST|UTokyo 285..380 blast score 190 percent identity 100 none 23613718 Hypothetical protein 8 putative transmembrane domains, possibly related to GNS1/SUR1 family. HMMPfam hit to PF01151, GNS1/SUR4 family; ScanProsite hit to PS01188, PS01188 Confirmed by InterPro eMOTIF pattern match. 23613719 Strong C-terminal similarities to chaperones from several organisms. last exon doesn't end with a stop codon. Similar to Neisseria meningitidis chaperone protein hscb or nma1598 SWALL:Q9JTW6 (EMBL:AL162756) (166 aa) fasta scores: E(): 0.0023, 41.42% id in 70 aa. HMMPfam hit to PF00226, DnaJ domain; HMMSmart hit to SM00271, DnaJ molecular chaperone homology domain; ProfileScan hit to PS50076, dnaJ domain profile. 23613720 Hypothetical protein. match to Pfa3D7|3745|2000.12.28|EST|UTokyo 36..500 blast score 914 percent identity 100 none 23613721 Hypothetical protein with N-terminal signal sequence. match to PfaDd2|2085c3|1999.12.28|EST|UFla 154..401blast score 464 percent identity 98 none 23613722 Hypothetical protein 23613723 ADP-ribosylation factor-like protein. Similar to Caenorhabditis elegans putative adp-ribosylation factor 2 f54c9.10 SW:ARF2_CAEEL (Q20758) (179 aa) fasta scores: E(): 2.7e-11, 31.319% id in 182 aa, and to Saccharomyces cerevisiae adp-ribosylation factor-like protein 1 arl1 or arf3 or ybr164c or ybr1216 SW:ARL1_YEAST (P38116) (183 aa) fasta scores: E(): 4.3e-11, 29.787% id in 188 aa. No pfam match; HMMSmart hit to SM00010;ScanProsite hit to PS00017, PS00294 23613725 Hypothetical protein. No pfam match, weak HMMSmart hit to SM00516, Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p) 23613726 Plasmodium falciparum inosine-5'-monophosphate dehydrogenase. Identical to Plasmodium falciparum TR:O96387 (EMBL:AF035679) (510 aa) fasta scores: E(): 3.1e-188, 99.608% id in 510 aa 23613727 Similar to Saccharomyces cerevisiae pes4 protein pes4 or yfr023W SWALL:PES4_YEAST (SWALL:P39684) (611 aa) fasta scores: E(): 4.1e-06, 23.03% id in 395 aa. HMMPfam hit to PF00076, RNA recognition motif.(a.k.a. RRM, RBD, or RNP domain); HMMSmart hit to SM00360, RNA recognition motif; ProfileScan hit to PS50102, Eukaryotic RNA Recognition Motif (RRM) profile. 23613728 Similar to Schizosaccharomyces pombe ubiquitin-conjugating enzyme e2 spbc1105.09 TR:Q9Y818 (EMBL:AL096851) (167 aa) fasta scores: E(): 7.6e-36, 56.875% id in 160 aa. match to PfaDd2|0101c3|1999.12.28|EST|UFla 118..257 blast score 278 percent identity 100 none. Similar to Homo sapiens ubiquitin-conjugating enzyme e2 g2 ube2g2 SWALL:UBCJ_HUMAN (SWALL:P56554) blast scores: E(): 3e-37, score: 379 49% id. HMMPfam hit to PF00179, Ubiquitin-conjugating enzyme 23613729 Hypothetical protein 23613730 Asparagine-rich hypothetical protein with 6 putative transmembrane domains 23613731 Hypothetical protein 23613732 Similar to Arabidopsis thaliana hypothetical 25.6 kDa protein TR:AAK44168 (EMBL:AF370353) (235 aa) fasta scores: E(): 0.00012, 28.834% id in 163 aa (except in first 70 amino acids in the N-terminal) ;single putative N-terminal transmembrane domain. HMMPfam hit (1.4e-09) to PF01106, NifU-like domain; BlastProDom hit to PD002830 23613733 The existence of the intron is uncertain, it is possible that it is a single exon gene that contains part of the reading frame shown as intron in the present gene model 23613734 Hypothetical protein. HMMPfam hit to PF00515, TPR Domain 23613735 Hypothetical protein with single putative N-terminal transmembrane domain 23613736 Hypothetical protein with 2 putative transmembrane doamins. Weakly similar to Arabidopsis thaliana hypothetical 39.8 kDa protein at4g01560 TR:Q9M125 (EMBL:AL161492) (343 aa) fasta scores: E(): 2.3e-18, 29.814% id in 322 aa. HMMPfam hit to PF01945, Domain of unknown function 23613737 Hypothetical protein 23613738 Hypothetical protein. Distantly related to dynein heavy chain with 5 putative WD40-like repeat domains. HMMPfam hit to PF00400, WD domain, G-beta repeat 23613739 Hypothetical protein with 2 putative transmembrane domains. match to Pfa3D7|5652|2000.12.28|EST|UTokyo 125..223 blast score 196 percent identity 100 none. HMMPfam hit to PF00240, Ubiquitin family; HMMSmart hit to SM00213, Ubiquitin homologues 23613740 Plasmodium falciparum (isolate 3D7), and s-adenosylmethionine synthetase maT TR:Q9GN14 (EMBL:AF097923) (402 aa) fasta scores: E(): 9.1e-162, 100.000% id in 402 aa. match to Pfa3D7|6402|2000.12.28|EST|UTokyo 1..500 blast score 983 percent identity 100 none. HMMPfam hit to PF00438, S-adenosylmethionine synthetase, N-terminal domain; HMMPfam hit to PF02772, S-adenosylmethionine synthetase, central domain; HMMPfam hit to PF02773, S-adenosylmethionine synthetase, C-terminal domain 23613741 Hypothetical protein single transmembrane domain 23613742 Plasmodium falciparum para-aminobenzoic acid synthetase TR:Q9Y1K0 (EMBL:AF119554) (979 aa) fasta scores: E(): 0, 99.792% id in 963 aa. HMMPfam hit to PF00117, Glutamine amidotransferase class-I; HMMPfam hit to PF00425, chorismate binding enzyme 23613743 Plasmodium falciparum phosphoglycerate kinase pgK SW:PGK_PLAFA (P27362) (416 aa) fasta scores: E(): 5.1e-150, 100.000% id in 416 aa. match to Pfa3D7|3971|2000.12.28|EST|UTokyo 212..500 blast score 573 percent identity 100 none 23613744 Similar to Rhizobium meliloti glutamine synthetase i glna or r01640 or smc00948 SW:GLN1_RHIME (Q59747) (469 aa) fasta scores: E(): 5.8e-34, 34.529% id in 446 aa 23613745 Similar to Homo sapiens hprp18 TR:Q99633 (EMBL:U51990) (342 aa) fasta scores: E(): 1.4e-23, 35.813% id in 363 aa. Putative pre-mRNA splicing factor protein. Pfam match to entry PF02840 Prp18, Prp18 domain, score 206.40, E-value 4.4e-58; HMMSmart hit to SM00500, Splicing Factor Motif, present in Prp18 and Pr04 23613746 Hypothetical protein with 2 putative transmembrane domains. match to Pfa3D7|4606|2000.12.28|EST|UTokyo 95..384 blast score 553 percent identity 99 none. match to Pfa3D7|6758|2000.12.28|EST|UTokyo 295..500 blast score 408 percent identity 100 none 23613747 Similar to Bacillus subtilis 3-oxoacyl-(acyl-carrier protein) reductase fabG SW:FABG_BACSU (P51831) (246 aa) fasta scores: E(): 4.9e-42, 52.697% id in 241 aa, and to Brassica napus 3-oxyacyl-(acyl carrier protein) reductase bkr2 TR:CAC41363 (EMBL:AJ243084) (328 aa) fasta scores: E(): 3.5e-38, 47.541% id in 244 aa. HMMPfam hit to PF00106, short chain dehydrogenase; ScanProsite hit to PS00061, Confirmed by InterPro eMOTIF pattern match. 23613748 Similar to Arabidopsis thaliana DNA-directed RNA polymerase II 36 kDa polypeptide a rpb36a or at2g15430 or f26h6.5 SW:RP3A_ARATH (Q39211) (319 aa) fasta scores: E(): 1.9e-24, 32.822% id in 326 aa. No pfam match; BlastProDom hit to PD002883; ScanProsite hit to PS00446, Confirmed by InterPro eMOTIF pattern match. 23613749 Hypothetical protein with weak Pfam hit to cysteine protease. HMMPfam hit to PF02338, OTU-like cysteine protease; ProfileScan hit to PS50802, OTU domain. 23613750 Similar to Cunninghamella elegans NADPH-dependent cytochrome p450 oxidoreductase TR:Q9P4E2 (EMBL:AF195659) (710 aa) fasta scores: E(): 4.6e-18, 24.795% id in 730 aa. Similarity to Arabidopsis thaliana NADPH-ferrihemoprotein reductase f9n11.60 or at4g30210 TR:Q9SUM3 (EMBL:AL109796) (711 aa) fasta scores: E(): 6e-16, 26.747% id in 744 aa and also to several others NADPH-ferrihemoprotein reductases and also to several others NADPH-ferrihemoprotein reductases. Similar to Phaseolus aureus NADPH-cytochrome p450 reductase SWALL:NCPR_PHAAU (SWALL:P37116) (690 aa) fasta scores: E(): 2.3e-15, 26.82% id in 738 aa. HMMPfam hit to PF00258, Flavodoxin; HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain 23613751 Similar to Plasmodium falciparum hypothetical 94.5 kDa protein mal4p2.23 TR:Q9U0J9 (EMBL:AL035475) (842 aa) fasta scores: E(): 2.4e-53, 26.878% id in 852 aa. Conserved hypothetical protein with N-terminal single putative transmembrane domain. HMMPfam hit to PF01823, MAC/Perforin domain; HMMSmart hit to SM00457, membrane-attack complex / perforin 23613752 Hypothetical protein 23613753 Hypotheical asperagine-rich protein 23613754 Hypothetical protein. Distant similarities with ligase-like proteins 23613755 Hypothetical protein 23613756 Plasmodium falciparum thioredoxin reductase tr or gR SW:TRXB_PLAF5 (Q25861) (541 aa) fasta scores: E(): 5.7e-207, 100.000% id in 541 aa. HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domainHMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreductase 23613757 Similar to Candida boidinii RNA-binding protein SWALL:Q9P4V6 (EMBL:AB023429) (255 aa) fasta scores: E(): 4.3e-21, 39.61% id in 207 aa, and to Drosophila melanogaster RNA binding protein pabp2 or rox2 or cg2163 SWALL:Q27926 (EMBL:L34934) (224 aa) fasta scores: E(): 1.3e-18, 39.13% id in 207 aa. HMMPfam hit to PF00076, RNA recognition motif.(a.k.a. RRM, RBD, or RNP domain); HMMSmart hit to SM00360, RNA recognition motif; ProfileScan hit to PS50102, Eukaryotic RNA Recognition Motif (RRM) profile 23613758 Hypothetical protein with 2 putative transmembrane domains. 23613759 Hypothetical protein 23613760 Hypothetical protein 23613761 Hypothetical protein 23613762 Hypothetical protein 23613763 Hypothetical protein with 13 putative transmembrane domains. HMMPfam hit to PF00520, Ion transport protein; ScanProsite hit to PS00284 23613764 Hypothetical asparagine-rich protein. match to Pfa3D7|7266|2000.12.28|EST|UTokyo 1..224 blast score 444 percent identity 100 none. match to Pfa3D7|7266|2000.12.28|EST|UTokyo 286..390 blast score 208 percent identity 100 none 23613765 Putative splicesome-associated protein. Moderately similar to Mus musculus splicing factor 3a, subunit 3, 60kd TR:AAH09141 (EMBL:BC009141) (501 aa) fasta scores: E(): 1.7e-24, 30.756% id in 595 aa. No significant pfam hit; HMMSmart hit to SM00355, zinc finger;ProfileScan hit to PS50171, Zn-finger (C2H2) in matrin and other RNA-binding proteins 23613766 Hypothetical protein with single putative transmembrane domain 23613767 Hypothetical protein 23613768 Hypothetical asparagine-rich protein with 4 putative transmembrane domains 23613769 Hypothetical protein. No pfam hit; ScanProsite hit to PS00430; Interpro hit to Ton-B dependant receptor protein 23613770 Similarities to prolyl-t-RNA synthases of bacterial origin; N-terminal signal peptide. Similar to Lactococcus lactis prolyl-trna synthetase pros or ll2127 SWALL:Q9CDT4 (EMBL:AE006441) (616 aa) fasta scores: E(): 1.6e-09, 35.21% id in 213 aa, and to Escherichia coli prolyl-trna synthetase pros or drpa or b0194 SWALL:SYP_ECOLI (SWALL:P16659) (572 aa) fasta scores: E(): 7.3e-08, 31.91% id in 235 aa. HMMPfam hit to PF00587, tRNA synthetase class II (G, H, P, S and T) 23613771 Plasmodium falciparum protein phosphatase-beta TR:O15920 (EMBL:U89025) (466 aa) fasta scores: E(): 1.9e-180, 99.142% id in 466 aa. HMMPfam hit to PF00149, Ser/Thr protein phosphatase; HMMSmart hit to SM00156, Protein phosphatase 2A homologues, catalytic domain. 23613772 Similar to Ictalurus punctatus thioredoxin TR:Q9DGI3 (EMBL:AF293651) (107 aa) fasta scores: E(): 2.7e-09, 38.202% id in 89 aa. Weak similarities to Plasmodium falciparum thioredoxin 1 txr1 TR:Q9NIR2 (EMBL:AF202664) (104 aa) fasta scores: E(): 3.7e-08, 34.884% id in 86 aa. HMMPfam hit to PF00085, Thioredoxin; ProfileScan hit to PS50223, Thioredoxin-domain (does not find all). 23613773 Similar to Arabidopsis thaliana zinc-binding protein-like TR:Q9FN32 (EMBL:AB007644) (129 aa) fasta scores: E(): 3.1e-20, 44.094% id in 127 aa and Similar to Arabidopsis thaliana hypothetical 14.8 kDa protein f11b9.15 TR:Q9C777 (EMBL:AC073395) (129 aa) fasta scores: E(): 9.6e-20, 48.031% id in 127 aa. Conserved hypothetical protein 23613774 Identical to Plasmodium falciparum histone deacetylase hdac1 TR:Q9XYC7 (EMBL:AF091326) (449 aa) fasta scores: E(): 3.9e-193, 100.000% id in 449 aa. HMMPfam hit to PF00850, Histone deacetylase family 23613775 Hypothetical protein 23613776 Hypothetical protein with N-terminal signal sequence. match to PfaDd2|2040c3|1999.12.28|EST|UFla 91..411 blast score 609 percent identity 99 none 23613777 match to PfaDd2|0468c3|1999.12.28|EST|UFla 113..213 blast score 182 percent identity 97 none. HMMPfam hit to PF02493, MORN repeat; HMMPfam hit to PF02493, MORN repeat; HMMPfam hit to PF00069, Protein kinase domain;HMMPfam hit to PF00069 (1.4e-13), Protein kinase domain 23613778 Hypothetical protein with similarity to protein kinases in the C-terminus. HMMPfam hit to PF00069, Protein kinase domain; HMMSmart hit to SM00219, Tyrosine kinase, catalytic domain; ProfileScan hit to PS50011, Protein kinase domain profile.; ScanProsite hit to PS00108, PS00108 Confirmed by InterPro eMOTIF pattern match. 23613779 Hypothetical protein. Hypothetical protein with single putative transmembrane domain at the N-terminus 23613780 putative protein kinase. Moderately similar to Plasmodium falciparum serine /threonine protein kinase crk-3 TR:O44022 (EMBL:X87839) (300 aa) fasta scores: E(): 2.6e-07, 25.000% id in 284 aa. HMMSmart hit to SM00219, Tyrosine kinase, catalytic domain; HMMPfam hit to PF00069, Protein kinase domain 23613781 Similar to Plasmodium falciparum membrane transporter pfb0465C TR:O96186 (EMBL:AE001396) (457 aa) fasta scores: E(): 1.5e-18, 28.185% id in 518 aa. 9 putative transmembrane domains. Similar to Sulfolobus solfataricus transport protein, permease sso2127 or c01003 SWALL:P95901 (EMBL:Y08256) (430 aa) fasta scores: E(): 0.029, 27.38% id in 157 aa. No pfam hit; ScanProsite hit to PS00589; Interpro hit to serine phosphorylation site in hpr protein 23613782 Hypothetical protein with 2 putative transmembrane domains. match to Pfa3D7|2459|2000.12.28|EST|UTokyo 1..402 blast score 791 percent identity 100 none 23613783 Hypothetical protein with 12 putative transmembrane domains 23613784 Moderate similarity to Drosophila melanogaster putative glutamine-dependent NAD cg9940 SW:NADE_DROME (Q9VYA0) (787 aa) fasta scores: E(): 1e-25, 25.721% id in 832 aa. Pfam match to entry PF02540 NAD_synthase, NAD synthase, score 43.50, E-value 4.8e-09 23613785 Hypothetical asparagine-rich protein 23613786 Hypothetical protein. Distantly similar to Drosophila melanogaster Cg6443 protein cg6443 TR:Q9VKR2 (EMBL:AE003629) (299 aa) fasta scores: E(): 1.7e-06, 30.290% id in 241 aa 23613787 Hypothetical protein. Moderate similarity to Mus musculus 2700047n05riK protein 2700047n05riK TR:Q9D0V4 (EMBL:AK004388) (157 aa) fasta scores: E(): 4.4e-08, 26.897% id in 145 aa. match to PfaDd2|2001c3|1999.12.28|EST|UFla 239..393 blast score 299 percent identity 99 none 23613788 Hypothetical protein 23613789 Hypothetical protein. Weak similarity to zinc finger domain, blast hit to HATPase_c domain at the N-terminus. HMMPfam hit to PF00642, Zinc finger C-x8-C-x5-C-x3-H type (and similar);HMMSmart hit to SM00356, zinc finger 23613790 match to Pfa3D7|1458|2000.12.28|EST|UTokyo 9..500 blast score 934 percent identity 99 none. Similar to Escherichia coli fumarate hydratase class i, aerobic fuma or b1612 SWALL:FUMA_ECOLI (SWALL:P00923) (547 aa) fasta scores: E(): 1.6e-80, 47.74% id in 576 aa 23613791 Hypothetical protein 23613792 Hypothetical protein with single putative C-terminal transmembrane domain 23613793 Hypothetical asperagine-rich protein. No pfam hit; FPrintScan hit to PR01497, Shal voltage-gated K+ channel family signature 23613794 Similar to Homo sapiens serine/threonine protein phosphatase 4 ppp4c or ppp4 or ppX SW:PPP4_HUMAN (P33172) (307 aa) fasta scores: E(): 5e-81, 62.278% id in 281 aa. HMMPfam hit to PF00149, Ser/Thr protein phosphatase;HMMSmart hit to SM00156, Protein phosphatase 2A FT homologues, catalytic domainProfileScan hit to PS50185, Metallo-phosphoesterase motif; FPrintScan hit to PR00114, Serine/threonine phosphatase family signature 23613795 Hypothetical protein. Similar to Dictyostelium discoideum cytochrome c oxidase polypeptide v cxeA SWALL:COX5_DICDI (SWALL:P29505) (119 aa) fasta scores: E(): 0.0068, 42.85% id in 56 aa, and to Oryza sativa cytochrome c oxidase subunit vb coxvB SWALL:P92683 (EMBL:D85381) (169 aa) fasta scores: E(): 2.8e-07, 35.13% id in 111 aa. Pfam match to entry PF01215 COX5B, Cytochrome c oxidase subunit Vb, score 23.90, E-value 1.9e-05; BlastProDom hit to PD007270 23613796 Plasmodium falciparum phosphatidylserine decarboxylase TR:Q9GPP8 (EMBL:AF312489) (353 aa) fasta scores: E(): 2e-129, 96.317% id in 353 aa. match to PfaDd2|2138c3|1999.12.28|EST|UFla 84..353 blast score 527 percent identity 100 none. Similar to Plasmodium falciparum phosphatidylserine decarboxylase SWALL:Q9GPP8 (EMBL:AF312489) (353 aa) fasta scores: E(): 3e-140, 99.43% id in 353 aa. Pfam match to entry PF02666 PS_Dcarbxylase, Phosphatidylserine decarboxylase, score 117.30, E-value 2.9e-31 23613797 Hypothetical protein, polypeptide related to cytochrome C oxidase like proteins 23613798 Hypothetical glutamic acid-rich protein 23613799 Hypothetical protein with single putative transmembrane domain 23613800 Hypothetical protein with single putative transmembrane domain 23613801 Hypothetical protein with 4 putative transmembrane domains 23613802 Hypothetical Lysine-rich protein 23613803 Hypothetical protein 23613804 Hypothetical protein 23613805 match to PfaDd2|0388c3|1999.12.28|EST|UFla 29..223 blast score 373 percent identity 99 none. Pfam match to entry PF00069 pkinase, Protein kinase domain, score 39.70, E-value 6.4e-10; HMMSmart hit to SM00220, Serine/Threonine protein kinases, catalytic domain; ProfileScan hit to PS50011, Protein kinase domain profile 23613806 Similar to Arabidopsis thaliana guanylate kinase gk-1 TR:Q9M683 (EMBL:AF204675) (387 aa) fasta scores: E(): 2.4e-21, 42.408% id in 191 aa. HMMPfam hit to PF00625, Guanylate kinase; HMMSmart hit to SM00072, Guanylate kinase homologues; ProfileScan hit to PS50052, Guanylate kinase domain profile;ScanProsite hit to PS00856, PS00856 Confirmed by InterPro eMOTIF pattern match. 23613807 Hypothetical protein 23613808 Hypothetical protein 23613809 HMMPfam hit to RNA-recognition motif (RRM, RBD or RNP domain), PF00076 (8e-12); HMMSmart hit (8.73e-06) to RNA-recognition motif (RRM) or RNP-1, SM00360; Interpro hit to IPR000504 23613810 Hypothetical protein with single putative transmembrane domain. No pfam match; Interpro hit to bipartite nuclear localisation signal 23613811 Hypothetical protein with N-terminal signal peptide. match to PfaDd2|2219c3|1999.12.28|EST|UFla 32..359 blast score 650 percent identity 100 none. match to Pfa3D7|7119|2000.12.28|EST|UTokyo 184..500 blast score 628 percent identity 100 none 23613812 With N-terminal similarity to Homo sapiens hypothetical 18.4 kDa protein dkfzp434i114 or dj1009e24.4 TR:Q9Y4P9 (EMBL:AL080154) (162 aa) fasta scores: E(): 1.5e-11, 41.600% id in 125 aa. No pfam hit; ProfileScan hit to PS50021, Calponin homology domain profile 23613813 Hypothetical protein 23613814 Hypothetical protein 23613815 Hypothetical protein with 2 putative transmembrane domains. Pfam match to entry PF02062 Lysyl_hydro, Lysyl hydrolase, score 18.00, E-value 6.9e-05 23613816 HMMPfam hit to PF00560, Leucine Rich Repeat; HMMSmart hit to SM00370 23613817 match to PfaDd2|1702c3|1999.12.28|EST|UFla 194..388 blast score 387 percent identity 100 none. match to PfaDd2|1183c3|1999.12.28|EST|UFla 1..122 blast score 242 percent identity 100 none. Similar to Plasmodium falciparum precursor of the major merozoite surface antigens SWALL:Q25922 (EMBL:Z35327) (1720 aa) fasta scores: E(): 0, 99.94% id in 1720 aa 23613818 Hypothetical protein with putative Myb DNA binding domain. Pfam match to entry PF00249 myb_DNA-binding, Myb-like DNA-binding domain, score 19.40, E-value 0.00077 HMMSmart hit to 'SM00395, SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains; ProfileScan hit to PS50090, Myb DNA-binding domain repeat profile 23613819 Pfam match to entry PF00130 DAG_PE-bind, Phorbol esters/diacylglycerol binding domain (C1 domain), score 19.10, E-value 0.00081; Pfam match to entry PF00609 DAGKa, Diacylglycerol kinase accessory domain (presumed), score 97.30, E-value 3e-25; HMMSmart hit to SM00045, Diacylglycerol kinase accessory domain (presumed); ProfileScan hit to PS50146, DAG-kinase domain; HMMPfam hit to PF00130, Phorbol esters/diacylglycerol binding domain (C1 domain); HMMSmart hit to SM00109, Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains) 23613820 putative peptidylprolyl isomerase. Similar to Arabidopsis thaliana peptidylprolyl isomerase TR:Q9FJX0 (EMBL:AB013390) (595 aa) fasta scores: E(): 7.2e-09, 24.375% id in 640 aa; probabably a cyclophilin family memmber but without PPIase or CsA-binding activity. match to PfaDd2|0173c3|1999.12.28|EST|UFla 20..85 blast score 131 percent identity 100 none. ProfileScan hit to PS50072, Cyclophilin-type peptidyl-prolyl cis-trans isomerase profile. 23613821 Hypothetical protein 23613822 Contains putative transmembrane domains. weak HMMPfam hit to PF00415, Regulator of chromosome condensation (RCC1); ProfileScan hit to PS50012, Regulator of chromosome condensation (RCC1) profile. 23613823 Similar to large number of elongation factors but clear outlier in a multiple alignment. Similar to Aeropyrum pernix elongation factor 1-alpha tuf or ape1844 SWALL:EF1A_AERPE (SWALL:Q9YAV0) blast scores: E(): 7e-10, score: 68 46% id. Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu family, score 66.20, E-value 1.9e-17; ScanProsite hit to PS00017 23613824 Hypothetical protein 23613825 Hypothetical protein with three putative transmembrane domains 23613826 Hypothetical protein 23613827 Hypothetical protein. Moderate similarity to Mus musculus unknown TR:AAH06701 (EMBL:BC006701) (297 aa) fasta scores: E(): 0.028, 28.962% id in 183 aa. ProfileScan hit to PS50030, Ubiquitin-associated domain. 23613828 Hypothetical protein with single transmembrane domain 23613829 Hypothetical protein 23613830 Hypothetical protein 23613831 Putative proteosome precursor. Similar to Nicotiana tabacum proteasome delta chain precursor SW:PRCD_TOBAC (P93395) (234 aa) fasta scores: E(): 3.3e-08, 28.689% id in 244 aa. Pfam match to entry PF00227 proteasome, Proteasome A-type and B-type, score 43.70, E-value 1.1e-10 and score 51.30, E-value 8.5e-13; ProfileScan hit to PS50247, Multispecific proteases of the proteasome. 23613832 Hypothetical protein 23613833 the last exon structure is uncertain 23613834 The last 2 exons are uncertain. match to PfaDd2|1024c3|1999.12.28|EST|UFla 93..151 blast score 117 percent identity 100 none. match to PfaDd2|1024c3|1999.12.28|EST|UFla 150..212 blast score 125 percent identity 100 none. HMMPfam hit to PF01595, Domain of unknown function DUF21 23613835 Similar to Eimeria acervulina 19 kDa sporozoite antigen TR:Q24777 (EMBL:Z26584) (170 aa) fasta scores: E(): 8e-21, 38.182% id in 165 aa, and to Eimeria acervulina sporozoite antigen easz240/160 ceasz240 TR:Q03777 (EMBL:M59500) (180 aa) fasta scores: E(): 9.8e-21, 38.182% id in 165 aa. HMMSmart hit to SM00392, Profilin /allergen 23613836 Similar to Homo sapiens aspartyl aminopeptidase TR:Q9ULA0 (EMBL:AF005050) (475 aa) fasta scores: E(): 1.5e-14, 30.742% id in 566 aa. Similar to Arabidopsis thaliana aspartyl aminopeptidase SWALL:Q9LST0 (EMBL:AB026632) blast scores: E(): 1e-56, score: 559 27% id. Pfam match to entry PF02127 Peptidase_M18, Aminopeptidase I zinc metalloprotease (M18), score 140.00, E-value 4.3e-38; FPrintScan hit to PR00932, Aminopeptidase I zinc metalloprotease (M18) signature; ScanProsite hit to PS00044 23613837 Similar to Aquifex aeolicus peptide chain release factor 1 prfa or aq_876 SW:RF1_AQUAE (O67032) (362 aa) fasta scores: E(): 1.5e-24, 31.818% id in 352 aa. Pfam match to entry PF00472 RF-1, Peptidyl-tRNA hydrolase domain, score 100.00, E-value 4.8e-26 23613838 4 putative transmembrane domains. Similar to Homo sapiens cDNA flj14524 fis, clone nt2rm1001008 SWALL:BAB55104 (EMBL:AK027430) (215 aa) fasta scores: E(): 6.5e-09, 45.2% id in 73 aa, and to Mus musculus 1190004a01riK protein 1190004a01riK SWALL:Q9D0T6 (EMBL:AK004475) (235 aa) fasta scores: E(): 2.6e-08, 50% id in 62 aa. Pfam match to entry PF01529 zf-DHHC, DHHC zinc finger domain, score 75.50, E-value 1.1e-18; ProfileScan hit to PS50216, DHHC-type Zn-finger; BlastProDom hit to PD003041 23613839 Similar to Neisseria meningitidis 30s ribosomal protein s6 rpsf or nmb1323 SWALL:RS6_NEIMB (SWALL:Q9JZ29) (122 aa) fasta scores: E(): 0.034, 28.57% id in 98 aa, and to Synechocystis sp 30s ribosomal protein s6 rpsf or rps6 or sll1767 SWALL:RS6_SYNY3 (SWALL:P73636) (113 aa) fasta scores: E(): 0.064, 25.68% id in 109 aa, and to Bacillus halodurans 30s ribosomal protein s6 rpsf or bh4050 SWALL:RS6_BACHD (SWALL:Q9K5N8) (95 aa) fasta scores: E(): 0.11, 36.06% id in 61 aa. HMMPfam hit to Ribosomal_S6 domain (1.5e-06), PF01250 23613840 Hypothetical protein. match to Pfa3D7|3779|2000.12.28|EST|UTokyo 128..260 blast score 264 percent identity 100 none. match to Pfa3D7|7164|2000.12.28|EST|UTokyo 37..500 blast score 858 percent identity 98 none 23613841 Hypothetical protein 23613842 asparagine-rich protein. Similar to Drosophila melanogaster cleavage stimulation factor 64 kilodalton subunit cstf-64 or cg7697 SWALL:Q9U4J2 (EMBL:AF170082) blast scores: E(): 8e-14, score: 80 49% id, and to Xenopus laevis polyadenylation factor 64 kDa subunit cstF SWALL:Q91581 (EMBL:U17394) blast scores: E(): 8e-12, score: 74 45% id, and to Mus musculus polyadenylation protein cstf64 cstf2 SWALL:Q9ERC2 (EMBL:AF317552) blast scores: E(): 8e-12, score: 74 45% id. Pfam match to entry PF00076 rrm, RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain), score 71.80, E-value 1.5e-17; HMMSmart hit to SM00360, RNA recognition motif; ProfileScan hit to PS50102, Eukaryotic RNA Recognition Motif(RRM) profile. 23613843 Hypothetical protein with single putative transmembrane domain 23613844 Hypothetical protein. match to PfaDd2|2233c3|1999.12.28|EST|UFla 115..192 blast score 155 percent identity 100 none. match to PfaDd2|2214c3|1999.12.28|EST|UFla 27..111 blast score 168 percent identity 100 none 23613845 Hypothetical protein with 2 putative transmebrane domains. match to Pfa3D7|2675|2000.12.28|EST|UTokyo 37..134 blast score 194 percent identity 100 none. match to Pfa3D7|3331|2000.12.28|EST|UTokyo 300..446 blast score 291 percent identity 100 none 23613846 Similar to Dictyostelium discoideum Spc98 protein spc98 SWALL:Q95ZG4 (EMBL:AJ318507) (812 aa) fasta scores: E(): 9.3e-15, 22.35% id in 653 aa, and to Schizosaccharomyces pombe spindle pole body component alp6 alp6 or spbc902.01c or spbc428.20C SWALL:ALP6_SCHPO (SWALL:Q9USQ2) (832 aa) fasta scores: E(): 3.1e-12, 24.71% id in 356 aa 23613847 Putative mitochondrial processing peptidase. Similar to Solanum tuberosum mitochondrial processing peptidase mpP TR:Q41445 (EMBL:X80237) (534 aa) fasta scores: E(): 3.9e-73, 43.354% id in 489 aa. Pfam match to entry PF00675 Peptidase_M16, Insulinase (Peptidase family M16), score 198.10, E-value 1.3e-55 23613849 Similar to Homo sapiens tubulin delta chain tubd1 or tubD SWALL:TBD_HUMAN (SWALL:Q9UJT1) (453 aa) fasta scores: E(): 3.7e-20, 25.64% id in 468 aa, and to Paramecium tetraurelia putative delta-like tubulin dpt1 SWALL:Q9GRI0 (EMBL:AJ401299) (399 aa) fasta scores: E(): 4.9e-20, 36.53% id in 219 aa. Pfam match to entry PF00091 tubulin, Tubulin/FtsZ family, score 61.80, E-value 5.9e-15; FPrintScan hit to PR01224, Delta-tubulin signature 23613850 Hypothetical protein 23613851 Hypothetical protein with N-terminal signal peptide 23613852 Similar to Arabidopsis thaliana nucleotide excision repair protein xp-d homolog TR:Q9SE44 (EMBL:AF188623) (758 aa) fasta scores: E(): 1.2e-80, 34.107% id in 991 aa. match to Pfa3D7|4157|2000.12.28|EST|UTokyo 1..174 blast score 331 percent identity 99 none. failed but should be on the forward strand, starting at 1343752 and ending at 1346544. Similar to Arabidopsis thaliana nucleotide excision repair protein xp-d homolog SWALL:Q9SE44 (EMBL:AF188623) (758 aa) fasta scores: E(): 3e-79, 34.06% id in 1042 aa, and to Dictyostelium discoideum RepD repD SWALL:O00836 (EMBL:U77066) (776 aa) fasta scores: E(): 3.8e-77, 34.17% id in 1030 aa, and to Schizosaccharomyces pombe DNA repair helicase rad15 rad15 or rhp3 or spac1d4.12 SWALL:RA15_SCHPO (SWALL:P26659) (772 aa) fasta scores: E(): 5.3e-75, 31.74% id in 1030 aa. Significant HMMSmart and Blast hit to DEXDc2 and HELICc2 domains 23613853 Hypothetical protein 23613854 Hypothetical protein with single putative transmembrane domain 23613855 Identical to Plasmodium falciparum hypothetical 10.4 kDa protein TR:Q9NFF9 (EMBL:AJ290939) (85 aa) fasta scores: E(): 3.1e-33, 100.000% id in 85 aa. Full length hypothetical protein reported as 10.4 kDa with EMBL entry no. AJ290939 23613856 last exon doesn't end with a stop codon. Similar to Citrus limon vacuolar ATP synthase subunit e vatE SWALL:VATE_CITLI (SWALL:Q9SWE7) blast scores: E(): 6e-34, score: 361 39% id, and to Arabidopsis thaliana vacuolar ATP synthase subunit e vate or at4g11150 or t22b4.130 or f2p3.10 SWALL:VATE_ARATH (SWALL:Q39258) blast scores: E(): 9e-33, score: 351 35% id, and to Gossypium hirsutum vacuolar ATP synthase subunit e vatE SWALL:VATE_GOSHI (SWALL:O23948) blast scores: E(): 1e-31, score: 342 37% id. Pfam hit to PF01991, vATP-synt_E domain, ATP synthase (E/31 kDa) subunit e-value 4.2e-52 23613857 Hypothetical protein 23613858 match to PfaDd2|0299c3|1999.12.28|EST|UFla 48..116 blast score 131 percent identity 99 none. weak HMMPfam hit to PF00789, UBX domain; HMMSmart hit to SM00166, Domain present in ubiquitin-regulatory proteins 23613859 Identical to Plasmodium falciparum camp-dependent protein kinase catalytic subunit pfpka or pkA TR:O15906 (EMBL:U78291) (342 aa) fasta scores: E(): 4.7e-145, 100.000% id in 342 aa. match to PfaDd2|0648c3|1999.12.28|EST|UFla 1..71 blast score 141 percent identity 100 none. Pfam match to entry PF00069 pkinase, Protein kinase domain, score 267.60, E-value 1.7e-76; HMMSmart hit to SM00220, Serine/Threonine protein kinases, catalytic domain; ProfileScan hit to PS50011, Protein kinase domain profile; FPrintScan hit to PR00109, Tyrosine kinase catalytic domain signature 23613860 Hypothetical protein 23613861 Similar to Homo sapiens u2 small nuclear ribonucleoprotein b snrpb2 SW:RU2B_HUMAN (P08579) (225 aa) fasta scores: E(): 3.3e-13, 38.914% id in 221 aa. weak HMMPfam hits to PF00076, RNA recognition motif.(a.k.a. RRM, RBD, or RNP domain); HMMSmart hit to SM00360, RNA recognition motif; ProfileScan hit to PS50102, Eukaryotic RNA Recognition Motif (RRM) profile. 23613862 Similarity to repeat region of Plasmodium falciparum aarp2 protein TR:Q94649 (EMBL:Y08924) (1360 aa) fasta scores: E(): 1.1e-15, 22.311% id in 874 aa. match to Pfa3D7|4207|2000.12.28|EST|UTokyo 169..497 blast score 617 percent identity 99 none. Similar to Rattus norvegicus vacuolar protein sorting homolog r-vps33a SWALL:Q63615 (EMBL:U35244) blast scores: E(): 3e-35, score: 380 22% id, and to Schizosaccharomyces pombe putative vacuolar protein sorting protein spbc1703.15C SWALL:Q9P7V6 (EMBL:AL136536) blast scores: E(): 9e-29, score: 324 24% id. HMMPfam hit to PF00995, Sec1 family (2.60e-04) 23613863 Hypothetical protein with single putative transmembrane domain and N-terminal signal peptide 23613864 Similar to Plasmodium falciparum novel orf on chromosome 9 TR:Q25986 (EMBL:X95373) (617 aa) fasta scores: E(): 0, 99.666% id in 599 aa 23613865 Hypothetical protein 23613866 Hypothetical protein 23613867 Hypothetical protein with single putative transmembrane domain 23613868 Similar to Plasmodium falciparum cytoadherence linked asexual protein clag9 TR:Q9NAV4 (EMBL:AF286130) (1339 aa) fasta scores: E(): 0, 99.239% id in 657 aa. match to Pfa3D7|5221|2000.12.28|EST|UTokyo 1..500 blast score 983 percent identity 100 none 23613869 Hypothetical protein with single putative transmembrane domains. match to PfaDd2|1010c3|1999.12.28|EST|UFla 1..388 blast score 769 percent identity 100 none 23613870 Hypothetical protein with single putative transmembrane domain 23613871 Hypothetical protein with 2 putative transmembrane domains and N-terminal signal peptide 23613872 Hypothetical protein with N-terminal signal peptide 23613873 Hypothetical protein with singe putative transmembrane domain 23613874 Hypothetical protein with single transmembrane domain 23613875 Hypothetical protein with single N-terminal transmembrane domain 23613876 Hypothetical protein. match to Pfa3D7|3433|2000.12.28|EST|UTokyo 1..318 blast score 537 percent identity 96 none 23613877 Weak hits to several lipase/phospholipases from several organisms. No pfam hit; ProfileScan hit to PS50187,Esterase/lipase/thioesterase active site serine. 23613878 Hypothetical protein with single transmembrane domain 23613879 Hypothetical protein. FPrintScan hit to PR01497, Shal voltage-gated K+ channel family signature 23613880 Hypothetical protein. No pfam hit; ScanProsite hit to PS00017; Interpro hit ATP/GTP-binding site motif A (P-loop) 23613881 Hypothetical protein with three putative transmembrane domain 23613882 Very weakly similar to Arabidopsis thaliana lysophospholipase-like protein t22p22_40 TR:Q9LYG5 (EMBL:AL163814) (390 aa) fasta scores: E(): 0.039, 22.965% id in 344 aa; weak similarity to several lysophospholipase/ phospholipases. ProfileScan hit to PS50187, Esterase/lipase/thioesterase active site serine. 23613883 Similar to Plasmodium falciparum variant surface antigen rifin 3 rif3 TR:Q9U737 (EMBL:AF161311) (350 aa) fasta scores: E(): 3.6e-58, 54.648% id in 355 aa. With 2 transmembrane domains. HMMPfam hit to PF02009, Rifin/stevor family 23613884 Similar to Plasmodium falciparum rifin, Mal1p4.06 mal1p4.06 TR:Q9NFB2 (EMBL:AL031747) (359 aa) fasta scores: E(): 5.4e-86, 77.008% id in 361 aa. With single transmembrane domain and N-terminal signal sequence. HMMPfam hit to PF02009, Rifin/stevor family 23613885 Similar to Plasmodium falciparum RifiN, mal1p4.04 rifiN TR:Q9NFB3 (EMBL:AL031747) (372 aa) fasta scores: E(): 1.8e-85, 71.091% id in 339 aa. HMMPfam hit to PF02009, Rifin/stevor family 23613886 Similar to Plasmodium falciparum var-like protein, Mal1p4.03 mal1p4.03 TR:Q9NFB4 (EMBL:AL031747) (1327 aa) fasta scores: E(): 0, 80.974% id in 1335 aa 23613887 Similar to Plasmodium falciparum Pfc1115W protein pfc1115W TR:O97311 (EMBL:AL034559) (371 aa) fasta scores: E(): 1.5e-75, 64.267% id in 375 aa. With single transmembrane domain. HMMPfam hit to PF02009, Rifin/stevor family 23613888 Similar to Plasmodium falciparum pfc0005w, mal3p8.1 protein TR:O97324 (EMBL:AL034560) (2209 aa) fasta scores: E(): 3.4e-107, 44.491% id in 2405 aa. HMMPfam hit to PF03011 23618958 Previously reported sequence (SWALL:Q25859 (EMBL:X69769)) has next methione codon as start codon 23618961 Contains putative transmembrane domains 23618962 hypothetical protein, contains DEXDc3 domain 23618963 Contains several weak Pfam matches to PF03130 phycobilisome lyase HEAT-like repeat 23618964 Possible DEAD box helicase 23618965 Pfam hit to PF01251 Ribosomal protein S7e 23618968 No pfam hit but similar to putative methyl transferase, not certain about function. 23618969 Pfam hit to PF00957 Synaptobrevin 23618972 Pfam hit to PF00999 Sodium/hydrogen exchanger family 23618987 Possible transmembrane domain present 23619006 Similar to several u1 small nuclear ribonucleoprotein a 23619013 Possible signal sequence present, so could be organellar 23619018 Contains CCAAT box factor domain 23619019 In TrEMBL entry, this protein appears wrongly as Plasmodium falciparum copper amine oxidase 23619029 Pfam hit to PF01246 Ribosomal protein L24e 23619030 Pfam and SMART hit to PP2C domain 23619034 Pfam hit to FtsJ-like methyltransferase 23619038 Similarity to several mitochondrial precursor of ATP synthase delta 23619040 Contains putative transmembrane domains 23619041 Pfam and SMART hits to FYVE zinc finger 23619043 Contains possible transmembrane domains 23619044 Pfam hit to PF00009 Elongation factor Tu GTP binding domain 23619046 Contains putative TPR repeats 23619047 Pfam hit to PF00312 Ribosomal protein S15 23619051 Similarity to several organellar ATP synthase gamma subunits 23619056 5' extension incorporated in the previously annotated gene model (SWALL:AMP1_PLAFQ (SWALL:O96935)) to include possible signal peptide / transmembrane domain 23619059 Contains possible GYF domain 23619063 Significant Pfam hit to PF00676 dehydrogenase_E1 component 23619070 Possible transmembrane domain present 23619071 Contains possible transmembrane, some similarity to other P. falciparum hypothetical proteins 23619074 Possible transmembrane domain present 23619079 Pfam hit to PF00551 Formyl transferase 23619080 Pfam hit to PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 23619082 Contains putative multiple transmembrane domains 23619084 Pfam hit to PF02545 Maf- like protein 23619085 Contains putative transmembrane domains 36329004782 Contains ankyrin repeats and possible transmembrane domain 23619086 hypothetical protein, contains possible transmembrane domain 23619089 Pfam entry to PF01661 Appr-1-p processing enzyme family 23619091 putative cargo protein, Pfam hit to PF01105 emp24/gp25L/p24 family 23619092 Putative lipoate protein ligase, Pfam hit to PF03099 Biotin/lipoate A/B protein ligase family 23619094 Pfam hit to PF00240 Ubiquitin family 23619095 Conatins putative VWA domain, Pfam hit to PF00628 PHD-finger 23619096 Contains possible transmembrane domains 23619097 Pfam hit to PF00069 Protein kinase domain 23619098 Possible transmembrane domain present 23619103 Pfam hit to PF01066 CDP- alcohol phosphatidyltransferase, contains putative transmembrane domain 23619105 Pfam hit to PF00249 Myb-like DNA-binding domain 23619106 low level similarity with exportin, no pfam 23619107 Possible phosphotransferase, SMART hit to SM0221 STYKc Protein kinase 23619109 Pfam hit to PF00025 ADP- ribosylation factor family 23619111 2x PF00397 WW domain, 3 x PF01846 FF domain 23619112 cholinephosphate cytidylyltransferase, SWALL entry starts at 530 (SWALL:CTPT_PLAFK (SWALL:P49587)); PMID:7588775 23619120 hypothetical protein, contains match to Zinc finger domain in Ran- binding proteins 23619121 Possible signal peptide present 23619124 Alternative exonI possible, Pfam hit to PF00203 Ribosomal protein S19 23619126 Contains possible 4 transmembrane domains 23619127 ferredoxin, contains possible signal sequence, Pfam hit to PF00111 2Fe-2S iron-sulfur cluster binding domain 23619128 Possible glycerol-3-p acyltransferase, no Pfam hit 23619130 Pfam hit to PF02463, RecF/RecN/SMC N terminal domain, Pfam hit to PF02483 SMC family, C-terminal domain 23619134 DnaJ/SEC63 protein 23619136 Possible transmembrane domain 23619137 MAL13P3.cand.5 - score = 89.80, hypothetical protein 23619139 Possible PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 23619143 Pfam hit to PF02985 HEAT repeat 23619144 Possible transmembrane domain present 23619145 hypothetical protein, possible signal sequence present 23619146 Slight difference exist when compared to the published sequence of EBL-1 from Dd2 strain of P. falciparum (PMID:10613703); The expression pattern of this gene is described in PMID:12000842; possible frameshift detected when compared to the ebl-1 open reading frame from strain Dd2 23619149 MAL13P3.cand.28 - score = 128.64, hypothetical protein 23619150 MAL13P3.C.cand.78 - score = 22.99, hypothetical protein, potential signal sequence, PF02617 Uncharacterized ACR, COG2127 23619151 PF00566 TBC domain 23619152 MAL13P3.C.cand.77 - score = 60.46, hypothetical protein 23619153 MAL13P3.C.cand.76 - score = 24.38, hypothetical protein 23619154 Pfam hit to PF00835 SNAP-25 family 23619155 small GTPase rab11, PF00025 ADP-ribosylation factor family, PF00009 Elongation factor Tu GTP binding domain, PF00071 Ras family 23619157 Hit to PF00364 Biotin-requiring enzyme, PF00198 2-oxo acid dehydrogenases acyltransferase (catalytic domain) By sequence comparison, this sequence encodes the dihydrolipoamide succinyltransferase (E2) domain of the 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61). A similar E2 domain (dihydrolipoamide transacylase, EC 2.3.1.-) is found in the branched-chain alpha-keto acid dehydrogenase complex and another E2 domain (dihydrolipoamide acetyltransferase, EC 2.3.1.12) is found in the pyruvate dehydrogenase complex. 23619158 PF00076 RNA recognition motif 23619159 MAL13P3.cand.34 - score = 64.32, hypothetical protein 23619160 hypothetical protein, possible N-terminal transmembrane domain 23619162 hypothetical protein, transmembrane domains first exon doesn't start with a start codon 23619163 Pfam hit to PF01529 DHHC zinc finger domain, transmembrane domains 23619164 Pfam hit to PF00233 3'5'-cyclic nucleotide phosphodiesterase, transmembrane domains 23619165 PF00233 3'5'-cyclic nucleotide phosphodiesterase, transmembrane domains 23619166 contains three PF00076 RNA recognition motifs 23619167 hypothetical protein, contains four potential transmembrane domains 23619168 potential signal peptide present 23619169 transmembrane domain present, Pfam hit to PF01150 GDA1/CD39 (nucleoside phosphatase) family 23619170 Contains Pfam PF00856 SET domain 23619171 MAL13P3.cand.45 - score = 192.54, hypothetical protein 23619172 MAL13P3.cand.46 - score = 187.24, hypothetical protein 23619173 MAL13P3.C.cand.68 - score = 164.18, hypothetical protein 23619174 MAL13P3.cand.49 - score = 66.42, hypothetical protein 23619175 Contains PF01529 DHHC zinc finger domain, PF00023 Ankyrin repeat, transmembrane domains 23619176 MAL13P3.C.cand.67 - score = 44.48, hypothetical protein 23619178 MAL13P3.cand.51 - score = 15.06, hypothetical protein 23619179 hypothetical protein, contains potential transmembrane domain 23619180 Pfam hit to PF01377 Thioester dehydrase 23619181 Pfam hit to PF00347 Ribosomal protein L6; L6 comprises 2 almost identical folds, suggesting that is was derived by the duplication of an ancient RNA-binding protein gene. Analysis reveals several sites on the protein surface where interactions with other ribosome components may occur, the N-terminus being involved in protein-protein interactions and the C-terminus containing possible RNA-binding sites 23619182 Similar to several Vacuolar (H+)-ATPase G subunits 23619183 Weal Pfam hit to PF00583 Acetyltransferase (GNAT) family 23619184 Pfam hit to PF00276 Ribosomal protein L23 23619185 Weak Pfam hit to PF00026 Eukaryotic aspartyl protease; possible transmembrane domains present; product call is based on weak Pfam hit and BLASTP evidence 23619186 Weak SMART hit to SM0464 LON domain, contains putative transmembrane domain; shows weak homology to liver stage-specific antigen 1 but the sequence homology is not strong enough for a prooduct call as a Plasmodium falciparum liver stage-specific antigen 1-like protein 23619187 possible signal peptide and transmembrane domains present 23619188 MAL13P3.C.cand.60 - score = 146.75, hypothetical protein 23619189 MAL13P3.cand.59 - score = 42.44, hypothetical protein 23619191 possible transmembrane domains present 23619193 Putative transmembrane domains present; Partial; N-terminal missing because contig ends 23619195 SMART hits to DEAD box helicase and Heicase-C terminal domain but no Pfam hit 23619196 Putative transmembrane domains present 23619197 Pfam hit to PF00957 Synaptobrevin 23619198 Bi-functional enzyme; folylpolyglutamate synthase (EC 6.3.2.17) is the enzyme of folate metabolism that catalyzes ATP-dependent addition of glutamate moieties to tetrahydrofolate. Its sequence is moderately conserved between prokaryotes (gene folC) and eukaryotes. 23619199 Pfam hits to PF00056 lactate/malate dehydrogenase, NAD binding domain, PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain; L-lactate dehydrogenase (EC 1.1.1.27) (LDH) [1] catalyzes the reversible NAD-dependent interconversion of pyruvate to L-lactate. In vertebrate muscles and in lactic acid bacteria it represents the final step in anaerobic glycolysis. This tetrameric enzyme is present in prokaryotic and eukaryotic organisms. Invertebrates there are three isozymes of LDH: the M form (LDH-A), found predominantly in muscle tissues; the H form (LDH-B), found in heart muscle and the X form (LDH-C), found only in the spermatozoa of mammals and birds. 23619200 Pfam hit to PF01423 Sm protein 23619201 Pfam match to PF00156 Phosphoribosyl transferase domain; in TrEMBL entry this protein starts at the next methionine codon 23619202 Pfam hit to PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain; it is certainly either function as a L-lactate dehydrogenase homologue or malate dehydrogenase homologue; but final product call requires further verification / experimental proof; another P. falciparum L-lactate dehydrogenase (SWALL:LDH1_PLAFD (SWALL:Q27743)) has been identified and expressed in E. coli (PMID: 8515777); Its crystal structure is reported in PMID:8901865 23619203 Matches to fragment of P.falciparum malaria antigen (M26-32-10) gene ((SWALL:Q25911 (EMBL:M63275)) 23619204 MAL13P3.cand.67 - score = 66.96, hypothetical protein 23619205 Pfam hit to PF00515 TPR Domain, transmembrane domain 23619206 MAL13P3.cand.69 - score = 199.62, hypothetical protein 23619207 MAL13P3.C.cand.46 - score = 345.67, hypothetical protein 23619208 MAL13P3.C.cand.45 - score = 24.85, hypothetical protein, potential transmembrane domain 23619209 MAL13P3.cand.71 - score = 35.06, hypothetical protein, PF00400 WD domain, G-beta repeat, PF01011 PQQ enzyme repeat 23619210 MAL13P3.C.cand.44 - score = 28.33, hypothetical protein 23619211 MAL13P3.C.cand.43 - score = 81.00, hypothetical protein, two PF00076 RNA recognition motifs 23619212 MAL13P3.C.cand.42 - score = 53.71, hypothetical protein 23619213 MAL13P3.C.cand.41 - score = 229.10, hypothetical protein, potential transmembrane domain 23619214 MAL13P3.cand.73 - score = 552.01, hypothetical protein 23619215 PF00962 Adenosine/AMP deaminase 23619216 Also similar to WD40/G-beta repeat protein Msi1 from several plant species; contains a long internal extension when compared to other chromatin assembly factor 1 / wd-40 repeat protein msi1 23619218 putative myosin, PF02736 Myosin N-terminal SH3-like domain, PF00063 Myosin head (motor domain) etc 23619219 PF00623 RNA polymerase alpha subunit, PF01854 RNA polymerase A/beta'/A subunit 23619220 hypothetical protein, presence of SM0580 PUG domain 23619221 Pfam hit to PF02146 Sir2 family 23619222 MAL13P3.cand.16 - score = 32.86, hypothetical protein 23619223 MAL13P3.cand.17 - score = 151.25, hypothetical protein 23619224 hypothetical protein, presence of possible transmembrane domain 23619225 hypothetical protein, presence of possible transmembrane domains 23619226 MAL13P3.C.cand.88 - score = 345.59, hypothetical protein 23619227 PF00227 Proteasome A-type and B-type 23619228 MAL13P3.cand.21 - score = 259.78, hypothetical protein 23619229 Pfam hit to PF00156 Phosphoribosyl transferase domain. Large N-terminal extension present. Phosphoribosyl pyrophosphate synthetase (EC 2.7.6.1) (PRPP synthetase)catalyzes the formation of PRPP from ATP and ribose 5-phosphate. PRPP is then used in various biosynthetic pathways, as for example in the formation of purines, pyrimidines, histidine and tryptophan. PRPP synthetase requires inorganic phosphate and magnesium ions for its stability and activity. 23619230 MAL13P3.cand.22 - score = 40.02, hypothetical protein, nonsesense mediated decay protein motif PF03467 Smg-4/UPF3 family 23619231 MAL13P3.C.cand.84 - score = 15.78, hypothetical protein, some similarities 23619232 MAL13P3.C.cand.83 - score = 82.21, hypothetical protein 23619233 MAL13P3.cand.23 - score = 35.79, hypothetical protein 23619234 MAL13P3.C.cand.82 - score = 298.09, hypothetical protein 23619235 MAL13P3.C.cand.81 - score = 36.01, hypothetical protein 23619236 MAL13P3.cand.26 - score = 19.30, hypothetical protein 23619237 MAL13P3.cand.27 - score = 119.52, hypothetical protein, possible transmembrane domain first exon doesn't start with a start codon 23619238 MAL13P3.cand.74 - score = 225.59, hypothetical protein 23619239 MAL13P3.C.cand.40 - score = 47.44, hypothetical protein 23619240 MAL13P3.C.cand.39 - score = 57.51, hypothetical protein, potential transmembrane domain 23619241 MAL13P3.cand.75 - score = 64.84, hypothetical protein 23619242 MAL13P3.cand.76 - score = 60.55, hypothetical protein 23619244 MAL13P3.cand.78 - score = 21.43, hypothetical protein, potential N-terminal transmembrane domain 23619245 MAL13P3.cand.79 - score = 15.20, hypothetical protein, potential N-terminal transmembrane domain 23619246 Pfam hit to PF00226 DnaJ domain 23619247 Contains signal sequence, Pfam hit to PF00810 ER lumen protein retaining receptor 23619248 Weak SMART hit to SM0667 LisH Lissencephaly type-1-like homology motif and SM0668 CTLH C-terminal to LisH motif 23619249 Pfam hit to PF00009 Elongation factor Tu GTP binding domain, PF03144 Elongation factor Tu domain 2, PF03143 Elongation factor Tu C-terminal domain 23619250 MAL13P3.cand.82 - score = 36.08, hypothetical protein with multiple transmembrane domains, some similarities 23619251 hypothetical protein, PF00076 RNA recognition motif, ser asp repeats, similar to fibrinogen binding proteins 23619252 Pfam hit to PF00069 Protein kinase domain 23619253 Pfam hit to PF00270 DEAD/DEAH box helicase, PF00271 Helicase conserved C-terminal domain 23619254 MAL13P3.cand.85 - score = 63.00, hypothetical protein 23619255 Pfam hit to PF00461 Signal peptidase I 23619256 MAL13P3.cand.87 - score = 71.50, hypothetical protein 23619257 MAL13P3.cand.88 - score = 98.37, hypothetical protein 23619258 MAL13P3.C.cand.32 - score = 15.16, hypothetical protein, transmembrane domains, not very satisfactory gene model 23619259 Pfam hit to PF00749 tRNA synthetases class I (E and Q) 23619260 Pfam hit to PF00238 Ribosomal protein L14p/L23e 23619261 Pfam hit to PF00804 Syntaxin 23619262 hypothetical protein, multiple transmembrane domains 23619263 MAL13P3.cand.93 - score = 150.23, hypothetical protein 23619265 MAL13P3.C.cand.28 - score = 94.89, hypothetical protein, some similarity, PF01909 Nucleotidyltransferase domain 23619267 Contains signal peptide, Pfam hit to PF01261 AP endonuclease family 2; other name of this gene product includes DNA-(apurinic or apyrimidinic site) lyase 23619268 Pfam hits to PF00270 DEAD/DEAH box helicase, PF00271 Helicase conserved C-terminal domain 23619269 Putative eukaryotic initiation factor 6, Pfam hit to PF01912 eIF-6 family 23619270 Pfam hit to PF00133 tRNA synthetases class I (I, L, M and V), could be extended at 5' as in phat prediction 23619271 Contains signal sequence, Pfam hit to 2 PF00166 Chaperonin 10 Kd subunits; thus it could be possible that 2 separate proteins with significant homology to PF00166 Chaperonin 10 Kd subunits have been represented here as one protein 23619272 MAL13P3.C.cand.22 - score = 71.94, hypothetical protein 23619273 Contains potential transmembrane domains 23619274 Putative Tmp21 cargo protein, contains signal sequence, Pfam hit to PF01105 emp24/gp25L/p24 family 23619275 Pfam hit to PF01871 Domain of unknown function DUF51 23619277 Contains > 2 PF00400 WD domains, G-beta repeats, contains transmembrane domains 23619278 Pfam hit to PF0012 Core histone H2A/H2B/H3/H4 23619279 MAL13P3.cand.102 - score = 41.93, hypothetical protein 23619280 MAL13P3.cand.103 - score = 138.28, hypothetical protein 23619281 Weak Pfam hit to PF00628 PHD-finger 23619282 MAL13P3.C.cand.16 - score = 104.06, hypothetical protein 23619283 MAL13P3.cand.104 - score = 87.22, hypothetical protein 23619284 Potential signal peptide present 23619285 Potential signal sequence present, MSP7-like protein family conserved in P. falciparum 23619286 Potential transmembrane domains present 23619287 potential signal sequence present 23619288 potential signal sequence present 23619289 MSP7-like protein family, putative signal peptide present 36329004987 Similar to MSP7 23619290 MSP7-like protein family 23619292 Reticulocyte binding protein 2 homolog B 23619302 Contains putative transmembrane domains 23619306 No PFAM hits 23619307 PF00579 tRNA synthetases class I (W and Y) 23619308 PF01432 Peptidase family M3 23619309 PF00069 Protein kinase domain 23619310 N-terminal transmembrane domain, PF02779 Transketolase, pyridine binding domain, PF02780 Transketolase, C-terminal domain 23619314 weak hit to PF00169 PH domain, associated with eukaryotic signaling proteins 23619315 putative calcium-dependent protein kinase, PF00069 Protein kinase domain, 4 x PF00036 EF hand 23619317 hypothetical transmembrane protein, low similarities to other hypothetical proteins (adjusted 5' exon, Bart) 23619318 putative proteasome regulatory component, PF01399 PCI domain 23619319 PF00467 KOW motif, PF01159 Ribosomal protein L6e. Homology to 60S subunit proteins 23619320 putative elongation factor 1-gamma, PF02798 Glutathione S-transferase, N-terminal domain, PF00043 Glutathione S-transferase, C-terminal domain, PF00647 Elongation factor 1 gamma, conserved domain 23619321 conserved hypothetical protein 23619326 PF00069 Protein kinase domain, potential N-terminal transmembrane domain 23619329 potential transmembrane domain 23619331 potential transmembrane domains 23619334 PF00664 ABC transporter transmembrane region, PF00005 ABC transporter 23619335 potential signal peptide 23619336 putative ribonuclease ph, PF01138 3' exoribonuclease family, domain 1 23619340 putative RNA lariat debranching enzyme, PF00149 Calcineurin-like phosphoesterase 23619342 Contains potential transmembrane domain 23619343 PF01384 Phosphate transporter family, PF01604 7TM chemoreceptor 23619344 Pfam hit to PF01775 Ribosomal L18ae protein family 23619345 Pfam hit to PF00828 Eukaryotic ribosomal protein L18 23619348 potential transmembrane domains 23619350 PF01813 ATP synthase subunit D 23619351 PF01092 Ribosomal protein S6e 23619352 Pfam hit to PF00330 Aconitase family (aconitate hydratase), PF00694 Aconitase C-terminal domain 23619353 hypothetical protein, potential transmembrane domains 23619354 PF00515 TPR Domain 23619355 PF01214 Casein kinase II regulatory subunit 23619356 potential signal peptide 23619357 Pfam hit to PF00063 Myosin head (motor domain) 23619358 SMART hit to SM0659 RPOLCX RNA polymerase subunit CX 23619359 Pfam hit to PF01293 Phosphoenolpyruvate carboxykinase 23619361 low match to PF01739 CheR methyltransferase, SAM binding domain 23619363 PF01170 Putative RNA methylase family UPF0020 23619365 putative DEAD/H helicase, PF00176 SNF2 family N-terminal domain, PF00097 Zinc finger, C3HC4 type (RING finger), PF00271 Helicase conserved C-terminal domain 23619367 PF01704 UTP--glucose-1-phosphate uridylyltransferase 23619368 Pfam hit to PF02214 K+ channel tetramerisation domain, 7X PF01344 Kelch motifs 23619370 potential N-terminal transmembrane region, PF02546 Lipoate synthase 23619372 N-terminal transmembrane domain, PF02729 OTCace_N, PF00185 OTCace 23619375 PF00097 Zinc finger, C3HC4 type (RING finger) 23619376 Pfam hit to PF00085 Thioredoxin 23619377 PF01694 Rhomboid family 23619379 Contains putative N-terminal transmembrane domain, Pfam hit to PF00179 Ubiquitin-conjugating enzyme 23619381 Pfam hit to PF00180 Isocitrate/isopropylmalate dehydrogenase 23619385 PF00344 eubacterial secY protein, contains putative signal sequence 23619387 PF01918 Protein of unknown function DUF78 23619391 Contains signal sequence and C-terminal transmembrane domain 23619392 Contains N- and C-terminal transmembrane domains 23619394 several PF00400 WD domain, G-beta repeat 23619395 PF01751 Toprim domain, PF01131 DNA topoisomerase 23619396 Contains transmembrane domains, Pfam hit to PF01733 Nucleoside transporter 23619400 2 x PF01467 Cytidylyltransferase 23619401 PF00560 Leucine Rich Repeats 23619404 Pfam hit to PF00071 Ras family, contains potential signal sequence 23619406 PF00009 Elongation factor Tu GTP binding domain, PF00679 Elongation factor G C-terminus 23619408 Pfam match to PF00566 TBC domain 23619414 Pfam hit to PF00293 NUDIX domain 23619415 Pfam hit to PF00749 tRNA synthetases class I (E and Q), catalytic domain 23619416 Pfam hit to PF00536 SAM domain (Sterile alpha motif), PF00069 Protein kinase domain 23619417 Pfam hit to PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 23619421 Pfam hit to PF03029; conserved hypothetical ATP binding protein 23619424 Pfam hits to PF01336 OB-fold nucleic acid binding domain, PF00152 tRNA synthetases class II (D, K and N) 23619425 Pfam hit to PF01423 Sm protein 23619433 Pfam match to PF02121 Phosphatidylinositol transfer protein, PF00169 PH domain, transmembrane regions 23619437 Pfam hit to PF00237 Ribosomal protein L22p/L17e 23619438 Pfam hit to PF00370 FGGY family of carbohydrate kinases, N-terminal domain, PF02782 FGGY family of carbohydrate kinases, C-terminal domain 23619443 Pfam hit to PF00664 ABC transporter transmembrane region, PF00005 ABC transporter 23619445 hypothetical protein last exon doesn't end with a stop codon 23619447 Contains putative signal peptide and transmembrane domain, Pfam hit to PF00085 Thioredoxin 23619448 partial hypothetical protein last exon doesn't end with a stop codon 23619450 conserved hypothetical protein, Pfam hit to PF03164 SAND family protein 23619453 hypothetical protein, potential transmembrane domains 23619454 hypothetical protein, potential transmembrane domain, fragment matches indicate transcribed in ring stage parasites 23619455 hypothetical protein, potential N-terminal transmembrane domains 23619456 hypothetical protein, PF00641 Zn-finger in Ran binding protein and others, PF00076 RNA recognition motif. 23619457 hypothetical protein, potential signal peptide, some similarity to transcription factors but no pfam 23619458 erd2, PF00810 ER lumen protein retaining receptor 23619459 hypothetical protein, potential transmembrane domains 23619460 PF00227 Proteasome A-type and B-type 23619461 Pfam hit to PF00227 Proteasome A-type and B-type 23619462 hypothetical protein, PF03179 Vacuolar (H+)-ATPase G subunit1 23619464 Pfam hit to PF02383 SacI homology domain, contains putative transmembrane domains 23619465 PF01728 FtsJ-like methyltransferase 23619466 PF00137 ATP synthase subunit C, signal peptide, transmembrane domains 23619467 identical to adsS fragment, PF00709 Adenylosuccinate synthetase 23619468 slight similarity to ribosomal proteins 23619470 N-terminal PF00168 C2 domain 23619473 putative replication licensing factor, Pfam hit to PF00493 MCM2/3/5 family 23619475 PF01753 MYND finger, PF00856 SET domain 23619476 three PF00515 TPR Domains,PF00149 Calcineurin-like phosphoesterase last exon doesn't end with a stop codon 23619483 some similarity to mitochondrial inner membrane translocase, contains potential transmembrane regions 23619484 PF00179 Ubiquitin-conjugating enzyme, PF00627 UBA/TS-N domain 23619486 hypothetical protein, potential transmembrane domains 23619487 hypothetical protein, some low level similarities 23619488 Pfam hit to PF00226 DnaJ domain, potential transmembrane domain 23619489 SM0220 S_TKc Serine/Threonine protein kinases, catalytic domain 23619490 PF00069 Protein kinase domain 23619491 PF00009 Elongation factor Tu GTP binding domain, PF03144 Elongation factor Tu domain 2, PF03143 Elongation factor Tu C-terminal domain 23619492 PF00009 Elongation factor Tu GTP binding domain, PF03144 Elongation factor Tu domain 2, PF03143 Elongation factor Tu C-terminal domain 23619493 PF00749 tRNA synthetases class I (E and Q), catalytic domain, N-terminal transmembrane domain 23619494 PF01221 Dynein light chain type 1 23619496 PF00270 DEAD/DEAH box helicase, PF00271 Helicase conserved C-terminal domain 23619498 PF00400 WD domain, G-beta repeats 23619499 PF00118, TCP-1/cpn60 chaperonin family 23619500 identical to fragment, PF01089 Delta 1-pyrroline-5-carboxylate reductase 23619501 all_bases.C.cand.66 - score = 207.41, PF01734 Patatin-like phospholipase, potential N-terminal transmembrane domain 23619502 all_bases.C.cand.65 - score = 156.07, hypothetical protein 23619504 all_bases.C.cand.64 - score = 15.19, PF01694 Rhomboid family, potential N-terminal transmembrane region 23619505 all_bases.cand.38 - score = 17.25, hypothetical protein, potential transmembrane domains 23619506 two PF03367 ZPR1 zinc-finger domains 23619507 all_bases.cand.40 - score = 136.89, three PF00642 Zinc finger C-x8-C-x5-C-x3-H type (and similar) 23619508 Pfam match to PF03134 TB2/DP1, HVA22 family 23619513 Possible bi-functional enzyme 23619517 all_bases.C.cand.62 - score = 291.24, hypothetical protein 23619518 hypothetical protein first exon doesn't start with a start codon last exon doesn't end with a stop codon 23619519 PF00025 ADP-ribosylation factor family 23619520 all_bases.cand.44 - score = 260.74, hypothetical protein, 4 potential transmembrane domains 23619521 all_bases.C.cand.61 - score = 11.70, hypothetical protein, potential transmembrane domain 23619522 Pfam hit to PF00076 RNA recognition motif 23619523 Contians three putative transmembrane domains 23619524 all_bases.C.cand.58 - score = 24.17, hypothetical protein, three potential transmembrane domains 23619525 all_bases.cand.46 - score = 42.20, hypothetical protein 23619526 two SM0044 CYCc Adenylyl- / guanylyl cyclase, catalytic domain, multiple transmembrane domains 23619527 all_bases.C.cand.56 - score = 58.43, hypothetical protein, probably spliced upstream 23619528 all_bases.C.cand.55 - score = 61.97, PF02037 SAP domain, PF00628 PHD-finger, PF02891 MIZ zinc finger, some low level similarities 23619530 three PF00076 RNA recognition motifs 23619534 all_bases.cand.52 - score = 8.66, hypothetical protein, 4 potential transmembrane domains 23619535 PF00241 Cofilin/tropomyosin-type actin-binding protein 23619536 all_bases.C.cand.50 - score = 30.87, PF00169 PH domain 23619537 all_bases.C.cand.49 - score = 16.60, hypothetical protein, some similarity to small hypotheticals 23619538 all_bases.cand.53 - score = 27.13, hypothetical protein, transmembrane domain very similar to region of cytochrome oxidase 23619539 all_bases.cand.54 - score = 304.83, SM0185 Armadillo/beta-catenin-like repeats 23619540 PF00705 Proliferating cell nuclear antigen, N-terminal domain, PF02747 Proliferating cell nuclear antigen, C-terminal domain 23619541 all_bases.cand.56 - score = 20.27, hypothetical protein, potential transmembrane domain 23619542 all_bases.C.cand.45 - score = 25.67, PF00244 14-3-3 protein 23619543 PF00004 ATPase family associated with various cellular activities (AAA) 23619544 Potential signal peptide and transmembrane domain present 23619545 all_bases.cand.58 - score = 232.34, PF00648 Calpain family cysteine protease first exon doesn't start with a start codon 23619546 all_bases.cand.59 - score = 56.19, PF01612 3'-5' exonuclease 23619547 all_bases.cand.60 - score = 38.52, hypothetical protein 23619549 all_bases.cand.63 - score = 54.39, hypothetical protein 23619550 all_bases.cand.64 - score = 128.72, hypothetical protein 23619551 all_bases.cand.65 - score = 207.08, hypothetical protein 23619552 all_bases.cand.66 - score = 86.31, hypothetical protein 23619553 all_bases.cand.67 - score = 102.71, hypothetical protein 23619554 some similarity to polynucleotide kinase 3' phosphatase 23619555 all_bases.cand.68 - score = 22.71, hypothetical protein 23619556 PF00400 WD domain, G-beta repeat 23619558 all_bases.C.cand.40 - score = 25.71, hypothetical protein 23619559 all_bases.cand.71 - score = 109.28, potential signal sequence, PF00218 Indole-3-glycerol phosphate synthase 23619560 all_bases.cand.73 hypothetical protein, potential signal peptide and transmembrane regions 23619561 all_bases.cand.75 - score = 81.15, hypothetical protein 23619562 all_bases.cand.76 - score = 75.87, potenial signal peptide and transmembrane region 23619563 all_bases.C.cand.38 - score = 188.96, hypothetical protein 23619564 PF00270 DEAD/DEAH box helicase, PF00271 Helicase conserved C-terminal domain 23619565 all_bases.cand.77 - score = 359.30, hypothetical protein, potential transmembrane 23619566 PF01138 3' exoribonuclease family, domain 1 23619567 PF00248 Aldo/keto reductase family 23619569 RNA polymerase Rpb5, C-terminal domain, putative RNA pol h 23619570 PF00762 Ferrochelatase 23619571 all_bases.cand.80 - score = 63.45, hypothetical protein 23619572 PF00366 Ribosomal protein S17 23619573 all_bases.C.cand.32 - score = 68.82, hypothetical protein 23619574 potential N-terminal transmembrane domain present, PF00899 ThiF family; specific product call is not possible because ThiF domain is found in proteins with different functions 23619575 PF01571 Glycine cleavage T-protein (aminomethyl transferase) 23619576 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, family 23619577 partially conserved hypothetical protein, contains 6 potential transmembrane domains 23619578 all_bases.cand.84 - score = 35.99, hypothetical protein 23619579 fused ubiquitin-ribosomal protein, PF00240 Ubiquitin family, PF01020 Ribosomal L40e family 23619581 conserved hypothetical protein 23619582 all_bases.cand.87 - score = 15.68, hypothetical protein, 2 potential transmembrane domains 23619583 all_bases.C.cand.28 - score = 428.30, hypothetical protein 23619584 all_bases.C.cand.27 - score = 60.67, hypothetical protein 23619586 PF00334 nucleoside diphosphate kinase 23619587 PF00448 SRP54-type protein, GTPase domain 23619589 potential signal sequence present, PF03034 Phosphatidyl serine synthase, presence of possible transmembrane domain 23619590 all_bases.cand.92 - score = 119.78, hypothetical protein 23619591 PF01466 Skp1 family, dimerisation domain; It is possible that this acts as cyclin a/cdk2-associated protein or kinetochore associated protein or transcription elongation factor B-like protein or glycoprotein fp21 precursor homologue; Thus, several putative function possible; no GO terms assigned 23619592 Pfam hit to PF00076 RNA recognition motif 23619594 hypothetical protein, potential N-terminal transmembrane domain 23619595 all_bases.cand.95 - score = 103.68, hypothetical protein 23619596 PF00970 Oxidoreductase FAD-binding domain, PF00175 Oxidoreductase NAD-binding domain, N-terminal transmembrane region or possible signal sequence; hits to several nitrate reductases of plant origin 23619597 conserved hypothetical protein 23619598 PF01411 tRNA synthetases class II (A), has long N-terminal extension 23619599 PF02987 Late embryogenesis abundant protein 23619600 all_bases.cand.99 - score = 69.41, potential signal peptide 23619601 PF01398 Mov34/MPN/PAD-1 family; shows high similarity to Schizosaccharomyces pombe pad1 protein that is involved in regulation of transcription factors; thus this might function like a S. pombe pad1 protein 23619602 PF00037 4Fe-4S binding domain, 2 x PF00005 ABC transporter; Several hits to ABC transporters but TMHMM2.0 does not reveal any transmembrane domain; Several hits to RNAse L inhibitor proteins 23619606 PF02953 Tim10/DDP family zinc finger 23619607 signal peptide, 3 x PF00153; Mitochondrial carrier protein 23619608 Good Pfam hit to PF02732 ERCC4 domain 23619609 all_bases.cand.105 - score = 54.92, hypothetical protein 23619610 hypothetical protein, transmembrane domains 23619611 all_bases.C.cand.8 - score = 62.05, hypothetical protein 23619612 all_bases.cand.108 - score = 200.63, hypothetical protein 23619614 hypothetical protein, three transmembrane domains 23619615 all_bases.cand.91 - score = 127.62, hypothetical protein 23619616 all_bases.C.cand.21 - score = 121.78, hypothetical protein 36329005316 VAR gene with single frameshift in exon I