-- dump date 20140619_131219 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_000001.1 45655915 2771345 292..1623 1 NC_005823.1 chromosomal replication initiator protein 1623 dnaA 2771345 dnaA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosomal replication initiator protein YP_000001.1 292 D 267671 CDS YP_000002.1 45655916 2771532 3279..4400 1 NC_005823.1 DNA polymerase III subunit beta 4400 dnaN 2771532 dnaN Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA polymerase III subunit beta YP_000002.1 3279 D 267671 CDS YP_000003.1 45655917 2772734 5062..6159 1 NC_005823.1 DNA repair and genetic recombination protein 6159 recF 2772734 recF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA repair and genetic recombination protein YP_000003.1 5062 D 267671 CDS YP_000004.1 45655918 2771828 6156..6620 1 NC_005823.1 hypothetical protein 6620 2771828 LIC10004 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000004.1 6156 D 267671 CDS YP_000005.1 45655919 2772064 6686..8605 1 NC_005823.1 DNA gyrase subunit B 8605 2772064 LIC10005 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA gyrase subunit B YP_000005.1 6686 D 267671 CDS YP_000006.1 45655920 2772010 8624..11128 1 NC_005823.1 type II topoisomerase; identified by sequence similarity; ORF located using Blastx/Glimmer; DNA gyrase subunit A 11128 gyrA 2772010 gyrA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA gyrase subunit A YP_000006.1 8624 D 267671 CDS YP_000007.1 45655921 2772392 11133..12122 1 NC_005823.1 nifR3-like protein 12122 2772392 LIC10007 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 nifR3-like protein YP_000007.1 11133 D 267671 CDS YP_000008.1 45655922 2770152 12129..12473 1 NC_005823.1 hypothetical protein 12473 2770152 LIC10008 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000008.1 12129 D 267671 CDS YP_000009.1 45655923 2770564 12715..13452 1 NC_005823.1 lipoprotein 13452 2770564 LIC10009 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000009.1 12715 D 267671 CDS YP_000010.1 45655924 2772277 complement(13804..14805) 1 NC_005823.1 hypothetical protein 14805 2772277 LIC10010 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000010.1 13804 R 267671 CDS YP_000011.1 45655925 2772563 complement(15216..15776) 1 NC_005823.1 outermembrane lipoprotein; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 15776 lipL21 2772563 lipL21 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000011.1 15216 R 267671 CDS YP_000012.1 45655926 2771594 15855..17462 1 NC_005823.1 hypothetical protein 17462 2771594 LIC10012 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000012.1 15855 D 267671 CDS YP_000013.1 45655927 2772422 17484..18377 1 NC_005823.1 sigma 54 activator 18377 2772422 LIC10013 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sigma 54 activator YP_000013.1 17484 D 267671 CDS YP_000014.1 45655928 2771930 complement(18319..19407) 1 NC_005823.1 hypothetical protein 19407 2771930 LIC10014 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000014.1 18319 R 267671 CDS YP_000015.1 45655929 2772740 19980..20195 1 NC_005823.1 hypothetical protein 20195 2772740 LIC10015 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000015.1 19980 D 267671 CDS YP_000016.1 45655930 2770512 complement(20186..20749) 1 NC_005823.1 Maf-like protein 20749 maf 2770512 maf Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Maf-like protein YP_000016.1 20186 R 267671 CDS YP_000017.1 45655931 2772255 20801..21706 1 NC_005823.1 hypothetical protein 21706 2772255 LIC10017 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000017.1 20801 D 267671 CDS YP_000018.1 45655932 2772084 21851..22354 1 NC_005823.1 lipoprotein 22354 2772084 LIC10018 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000018.1 21851 D 267671 CDS YP_000019.1 45655933 2771430 22359..23102 1 NC_005823.1 3-oxoacyl-ACP reductase 23102 2771430 LIC10019 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-oxoacyl-ACP reductase YP_000019.1 22359 D 267671 CDS YP_000020.1 45655934 2771733 23118..23726 1 NC_005823.1 hypothetical protein 23726 2771733 LIC10020 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000020.1 23118 D 267671 CDS YP_000021.1 45655935 2769867 24216..25898 1 NC_005823.1 contains alpha integrin like repeat domains; identified by sequence similarity; ORF located using Blastx/Glimmer; lipoprotein 25898 2769867 LIC10021 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000021.1 24216 D 267671 CDS YP_000022.1 45655936 2772457 complement(26728..27090) 1 NC_005823.1 arsenate reductase 27090 2772457 LIC10022 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 arsenate reductase YP_000022.1 26728 R 267671 CDS YP_000023.1 45655937 2770572 28185..29198 1 NC_005823.1 flagellar motor switch protein; One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 29198 fliG 2770572 fliG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar motor switch protein G YP_000023.1 28185 D 267671 CDS YP_000024.1 45655938 2770023 29263..31539 1 NC_005823.1 adenylate/guanylate cyclase 31539 2770023 LIC10024 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_000024.1 29263 D 267671 CDS YP_000025.1 45655939 2772604 32228..32785 1 NC_005823.1 hypothetical protein 32785 2772604 LIC10025 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000025.1 32228 D 267671 CDS YP_000026.1 45655940 2769844 32934..33959 1 NC_005823.1 hypothetical protein 33959 2769844 LIC10026 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000026.1 32934 D 267671 CDS YP_000027.1 45655941 2772257 34184..34888 1 NC_005823.1 hypothetical protein 34888 2772257 LIC10027 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000027.1 34184 D 267671 CDS YP_000028.1 45655942 2772015 34892..35251 1 NC_005823.1 lipoprotein 35251 2772015 LIC10028 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000028.1 34892 D 267671 CDS YP_000029.1 45655943 2770002 complement(35248..36096) 1 NC_005823.1 inositol monophosphatase 36096 2770002 LIC10029 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 inositol monophosphatase YP_000029.1 35248 R 267671 CDS YP_000030.1 45655944 2770164 complement(36116..37027) 1 NC_005823.1 hypothetical protein 37027 2770164 LIC10030 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000030.1 36116 R 267671 CDS YP_000031.1 45655945 2772289 complement(37639..39615) 1 NC_005823.1 beta-galactosidase 39615 lacZ 2772289 lacZ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 beta-galactosidase YP_000031.1 37639 R 267671 CDS YP_000032.1 45655946 2772698 39801..40658 1 NC_005823.1 hypothetical protein 40658 2772698 LIC10032 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000032.1 39801 D 267671 CDS YP_000033.1 45655947 2771636 40666..41238 1 NC_005823.1 hypothetical protein 41238 2771636 LIC10033 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000033.1 40666 D 267671 CDS YP_000034.1 45655948 2770086 41220..41915 1 NC_005823.1 hypothetical protein 41915 2770086 LIC10034 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000034.1 41220 D 267671 CDS YP_000035.1 45655949 2770450 41921..44176 1 NC_005823.1 ribonuclease R 44176 rnR 2770450 rnR Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribonuclease R YP_000035.1 41921 D 267671 CDS YP_000036.1 45655950 2769639 44336..44848 1 NC_005823.1 hypothetical protein 44848 2769639 LIC10036 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000036.1 44336 D 267671 CDS YP_000037.1 45655951 2771124 44852..46465 1 NC_005823.1 GMC oxidoreductase 46465 2771124 LIC10037 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GMC oxidoreductase YP_000037.1 44852 D 267671 CDS YP_000038.1 45655952 2772745 46607..48115 1 NC_005823.1 internal repeat sequences detected; contains TPR domain as detected by pfam-hmmr; hypothetical protein 48115 2772745 LIC10038 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000038.1 46607 D 267671 CDS YP_000039.1 45655953 2770131 complement(48326..49030) 1 NC_005823.1 3-dehydroquinate dehydratase 49030 aroD 2770131 aroD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-dehydroquinate dehydratase YP_000039.1 48326 R 267671 CDS YP_000040.1 45655954 2771585 complement(49034..50002) 1 NC_005823.1 polysialic acid capsule expression protein 50002 kpsF 2771585 kpsF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 polysialic acid capsule expression protein YP_000040.1 49034 R 267671 CDS YP_000041.1 45655955 2770936 complement(49986..50525) 1 NC_005823.1 transcription activator or transcription antitermination factor 50525 2770936 LIC10041 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transcription activator or transcription antitermination factor YP_000041.1 49986 R 267671 CDS YP_000042.1 45655956 2772090 complement(50509..50988) 1 NC_005823.1 hypothetical protein 50988 2772090 LIC10042 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000042.1 50509 R 267671 CDS YP_000043.1 45655957 2769561 52070..53767 1 NC_005823.1 methyl-accepting chemotaxis transmembrane protein; aerotaxis receptor; Aer 53767 aer 2769561 aer Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Aer YP_000043.1 52070 D 267671 CDS YP_000044.1 45655958 2771500 54372..55250 1 NC_005823.1 hypothetical protein 55250 2771500 LIC10044 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000044.1 54372 D 267671 CDS YP_000045.1 45655959 2769976 55247..56185 1 NC_005823.1 dTDP-glucose 4-6-dehydratase 56185 2769976 LIC10045 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dTDP-glucose 4-6-dehydratase YP_000045.1 55247 D 267671 CDS YP_000046.1 45655960 2772119 56259..57428 1 NC_005823.1 proton-translocating transhydrogenase subunit alpha part 1 57428 pntA 2772119 pntA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 proton-translocating transhydrogenase subunit alpha part 1 YP_000046.1 56259 D 267671 CDS YP_000047.1 45655961 2772441 complement(57387..57923) 1 NC_005823.1 hypothetical protein 57923 2772441 LIC10047 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000047.1 57387 R 267671 CDS YP_000048.1 45655962 2772248 complement(57920..59239) 1 NC_005823.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 59239 hisS 2772248 hisS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidyl-tRNA synthetase YP_000048.1 57920 R 267671 CDS YP_000049.1 45655963 2772699 complement(59246..60394) 1 NC_005823.1 hypothetical protein 60394 2772699 LIC10049 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000049.1 59246 R 267671 CDS YP_000050.1 45655964 2770516 complement(60404..62467) 1 NC_005823.1 OmpA-like; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 62467 2770516 LIC10050 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000050.1 60404 R 267671 CDS YP_000051.1 45655965 2771522 62561..63403 1 NC_005823.1 7,8-dihydropteroate synthase protein 63403 folP 2771522 folP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 7,8-dihydropteroate synthase protein YP_000051.1 62561 D 267671 CDS YP_000052.1 45655966 2772149 complement(64172..65422) 1 NC_005823.1 hypothetical protein 65422 2772149 LIC10052 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000052.1 64172 R 267671 CDS YP_000053.1 45655967 2771040 complement(65480..66382) 1 NC_005823.1 hypothetical protein 66382 2771040 LIC10053 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000053.1 65480 R 267671 CDS YP_000054.1 45655968 2772157 66432..67397 1 NC_005823.1 lipoprotein 67397 rlpA 2772157 rlpA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000054.1 66432 D 267671 CDS YP_000055.1 45655969 2770472 complement(68117..68824) 1 NC_005823.1 serine acetyltransferase 68824 cysE 2770472 cysE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 serine acetyltransferase YP_000055.1 68117 R 267671 CDS YP_000056.1 45655970 2770424 69026..69952 1 NC_005823.1 hypothetical protein 69952 2770424 LIC10056 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000056.1 69026 D 267671 CDS YP_000057.1 45655971 2771529 70123..71331 1 NC_005823.1 hypothetical protein 71331 2771529 LIC10057 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000057.1 70123 D 267671 CDS YP_000058.1 45655972 2772137 complement(72115..73497) 1 NC_005823.1 MATE; identified by sequence similarity; ORF located using Blastx/Glimmer; drug:Na+ antiporter 73497 2772137 LIC10058 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 drug:Na+ antiporter YP_000058.1 72115 R 267671 CDS YP_000059.1 45655973 2770797 complement(73514..74797) 1 NC_005823.1 proton glutamate symport protein 74797 2770797 LIC10059 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 proton glutamate symport protein YP_000059.1 73514 R 267671 CDS YP_000060.1 45655974 2771194 74937..78122 1 NC_005823.1 hypothetical protein 78122 2771194 LIC10060 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000060.1 74937 D 267671 CDS YP_000061.1 45655975 2770160 78115..79005 1 NC_005823.1 hypothetical protein 79005 2770160 LIC10061 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000061.1 78115 D 267671 CDS YP_000062.1 45655976 2770781 79606..79833 1 NC_005823.1 hypothetical protein 79833 2770781 LIC10062 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000062.1 79606 D 267671 CDS YP_000063.1 45655977 2770544 79879..83085 1 NC_005823.1 histidine kinase sensor protein 83085 2770544 LIC10063 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_000063.1 79879 D 267671 CDS YP_000064.1 45655978 2771267 complement(83798..84280) 1 NC_005823.1 hypothetical protein 84280 2771267 LIC10064 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000064.1 83798 R 267671 CDS YP_000065.1 45655979 2772651 complement(84344..84865) 1 NC_005823.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 84865 dcd 2772651 dcd Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 deoxycytidine triphosphate deaminase YP_000065.1 84344 R 267671 CDS YP_000066.1 45655980 2770552 complement(84866..85648) 1 NC_005823.1 enoyl-CoA hydratase/isomerase family protein 85648 2770552 LIC10066 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 enoyl-CoA hydratase/isomerase family protein YP_000066.1 84866 R 267671 CDS YP_000067.1 45655981 2769497 85681..86475 1 NC_005823.1 hypothetical protein 86475 2769497 LIC10067 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000067.1 85681 D 267671 CDS YP_000068.1 45655982 2769803 87380..87589 1 NC_005823.1 hypothetical protein 87589 2769803 LIC10068 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000068.1 87380 D 267671 CDS YP_000069.1 45655983 2769548 complement(87678..88076) 1 NC_005823.1 glyoxylase I 88076 glo1 2769548 glo1 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glyoxylase I YP_000069.1 87678 R 267671 CDS YP_000070.1 45655984 2769504 complement(88156..89244) 1 NC_005823.1 hypothetical protein 89244 2769504 LIC10070 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000070.1 88156 R 267671 CDS YP_000071.1 45655985 2770893 complement(89241..90881) 1 NC_005823.1 hypothetical protein 90881 2770893 LIC10071 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000071.1 89241 R 267671 CDS YP_000072.1 45655986 2770395 90975..91724 1 NC_005823.1 hypothetical protein 91724 2770395 LIC10072 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000072.1 90975 D 267671 CDS YP_000073.1 45655987 2770387 complement(91713..92564) 1 NC_005823.1 3-demethylubiquinone-9 3-methyltransferase 92564 2770387 LIC10073 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-demethylubiquinone-9 3-methyltransferase YP_000073.1 91713 R 267671 CDS YP_000074.1 45655988 2769936 92703..93548 1 NC_005823.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 93548 dapF 2769936 dapF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 diaminopimelate epimerase YP_000074.1 92703 D 267671 CDS YP_000075.1 45655989 2772470 complement(93555..94265) 1 NC_005823.1 hypothetical protein 94265 2772470 LIC10075 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000075.1 93555 R 267671 CDS YP_000076.1 45655990 2771263 complement(94298..94582) 1 NC_005823.1 hypothetical protein 94582 2771263 LIC10076 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000076.1 94298 R 267671 CDS YP_000077.1 45655991 2772722 96008..96355 1 NC_005823.1 hypothetical protein 96355 2772722 LIC10077 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000077.1 96008 D 267671 CDS YP_000078.1 45655992 2772249 complement(96359..96934) 1 NC_005823.1 hypothetical protein 96934 2772249 LIC10078 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000078.1 96359 R 267671 CDS YP_000079.1 45655993 2770598 complement(97126..97659) 1 NC_005823.1 hypothetical protein 97659 2770598 LIC10079 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000079.1 97126 R 267671 CDS YP_000080.1 45655994 2772304 complement(98030..98851) 1 NC_005823.1 hypothetical protein 98851 2772304 LIC10080 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000080.1 98030 R 267671 CDS YP_000081.1 45655995 2770621 complement(99567..99887) 1 NC_005823.1 hypothetical protein 99887 2770621 LIC10082 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000081.1 99567 R 267671 CDS YP_000082.1 45655996 2772210 complement(99931..100377) 1 NC_005823.1 hypothetical protein 100377 2772210 LIC10083 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000082.1 99931 R 267671 CDS YP_000083.1 45655997 2772235 100706..101953 1 NC_005823.1 RNA methyltransferase 101953 2772235 LIC10086 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA methyltransferase YP_000083.1 100706 D 267671 CDS YP_000084.1 45655998 2771963 102232..102891 1 NC_005823.1 hypothetical protein 102891 2771963 LIC10087 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000084.1 102232 D 267671 CDS YP_000085.1 45655999 2771354 103786..105066 1 NC_005823.1 hypothetical protein 105066 2771354 LIC10088 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000085.1 103786 D 267671 CDS YP_000086.1 45656000 2770924 105286..106011 1 NC_005823.1 hypothetical protein 106011 2770924 LIC10089 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000086.1 105286 D 267671 CDS YP_000087.1 45656001 2771145 106049..107596 1 NC_005823.1 internal repeat sequences detected; contains PBS lyase HEAT-like repeat as detected by pfam-hmmr; hypothetical protein 107596 2771145 LIC10090 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000087.1 106049 D 267671 CDS YP_000088.1 45656002 2770299 107605..108648 1 NC_005823.1 lipoprotein 108648 2770299 LIC10091 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000088.1 107605 D 267671 CDS YP_000089.1 45656003 2769627 108645..109502 1 NC_005823.1 metallo-beta-lactamase 109502 2769627 LIC10092 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 metallo-beta-lactamase YP_000089.1 108645 D 267671 CDS YP_000090.1 45656004 2770050 complement(109973..110899) 1 NC_005823.1 hypothetical protein 110899 2770050 LIC10093 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000090.1 109973 R 267671 CDS YP_000091.1 45656005 2770536 complement(111018..113075) 1 NC_005823.1 long-chain-fatty-acid CoA ligase 113075 2770536 LIC10094 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 long-chain-fatty-acid CoA ligase YP_000091.1 111018 R 267671 CDS YP_000092.1 45656006 2771057 complement(113248..113604) 1 NC_005823.1 hypothetical protein 113604 2771057 LIC10095 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000092.1 113248 R 267671 CDS YP_000093.1 45656007 2772131 complement(113577..114236) 1 NC_005823.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 114236 aat 2772131 aat Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 leucyl/phenylalanyl-tRNA--protein transferase YP_000093.1 113577 R 267671 CDS YP_000094.1 45656008 2771770 complement(114286..114834) 1 NC_005823.1 2'-5' RNA ligase 114834 ligT 2771770 ligT Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 2'-5' RNA ligase YP_000094.1 114286 R 267671 CDS YP_000095.1 45656009 2771979 complement(114882..116657) 1 NC_005823.1 para-aminobenzoate synthase component I 116657 pabB 2771979 pabB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 para-aminobenzoate synthase component I YP_000095.1 114882 R 267671 CDS YP_000096.1 45656010 2770403 116680..118833 1 NC_005823.1 histidine kinase sensor protein 118833 2770403 LIC10099 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_000096.1 116680 D 267671 CDS YP_000097.1 45656011 2770166 complement(119602..119805) 1 NC_005823.1 hypothetical protein 119805 2770166 LIC10100 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000097.1 119602 R 267671 CDS YP_000098.1 45656012 2771431 complement(120143..121645) 1 NC_005823.1 cystathionine gamma-synthase 121645 met-7 2771431 met-7 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cystathionine gamma-synthase YP_000098.1 120143 R 267671 CDS YP_000099.1 45656013 2769850 complement(121705..122769) 1 NC_005823.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 122769 prfA 2769850 prfA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peptide chain release factor 1 YP_000099.1 121705 R 267671 CDS YP_000100.1 45656014 2770355 122810..123415 1 NC_005823.1 hypothetical protein 123415 2770355 LIC10103 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000100.1 122810 D 267671 CDS YP_000101.1 45656015 2769582 123498..124757 1 NC_005823.1 hypothetical protein 124757 2769582 LIC10104 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000101.1 123498 D 267671 CDS YP_000102.1 45656016 2772175 complement(125107..126129) 1 NC_005823.1 hypothetical protein 126129 2772175 LIC10105 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000102.1 125107 R 267671 CDS YP_000103.1 45656017 2770569 complement(126141..126476) 1 NC_005823.1 hypothetical protein 126476 2770569 LIC10106 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000103.1 126141 R 267671 CDS YP_000104.1 45656018 2772352 complement(127043..127711) 1 NC_005823.1 hypothetical protein 127711 2772352 LIC10107 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000104.1 127043 R 267671 CDS YP_000105.1 45656019 2772773 complement(127689..127910) 1 NC_005823.1 hypothetical protein 127910 2772773 LIC10108 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000105.1 127689 R 267671 CDS YP_000106.1 45656020 2770723 complement(128049..128318) 1 NC_005823.1 hypothetical protein 128318 2770723 LIC10109 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000106.1 128049 R 267671 CDS YP_000107.1 45656021 2769534 128306..128755 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 128755 2769534 LIC10110 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000107.1 128306 D 267671 CDS YP_000108.1 45656022 2771234 129999..130619 1 NC_005823.1 imidazoleglycerol-phosphate dehydratase 130619 hisB 2771234 hisB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 imidazoleglycerol-phosphate dehydratase YP_000108.1 129999 D 267671 CDS YP_000109.1 45656023 2771039 130616..131248 1 NC_005823.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 131248 hisH 2771039 hisH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 imidazole glycerol phosphate synthase subunit HisH YP_000109.1 130616 D 267671 CDS YP_000110.1 45656024 2772458 131245..131970 1 NC_005823.1 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase protein 131970 hisA 2772458 hisA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase protein YP_000110.1 131245 D 267671 CDS YP_000111.1 45656025 2771385 132061..133275 1 NC_005823.1 hypothetical protein 133275 2771385 LIC10115 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000111.1 132061 D 267671 CDS YP_000112.1 45656026 2771009 133299..133823 1 NC_005823.1 hypothetical protein 133823 2771009 LIC10116 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000112.1 133299 D 267671 CDS YP_000113.1 45656027 2772281 134195..136045 1 NC_005823.1 hypothetical protein 136045 2772281 LIC10117 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000113.1 134195 D 267671 CDS YP_000114.1 45656028 2770821 complement(137048..137869) 1 NC_005823.1 phoshomethylpyrimidine kinase protein 137869 thiD 2770821 thiD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phoshomethylpyrimidine kinase protein YP_000114.1 137048 R 267671 CDS YP_000115.1 45656029 2771894 complement(138884..139297) 1 NC_005823.1 methylated-DNA--protein-cysteine methyltransferase 139297 2771894 LIC10119 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methylated-DNA--protein-cysteine methyltransferase YP_000115.1 138884 R 267671 CDS YP_000116.1 45656030 2772445 complement(140027..141856) 1 NC_005823.1 histidine kinase sensor protein 141856 2772445 LIC10120 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_000116.1 140027 R 267671 CDS YP_000117.1 45656031 2772071 141874..142830 1 NC_005823.1 hypothetical protein 142830 2772071 LIC10121 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000117.1 141874 D 267671 CDS YP_000118.1 45656032 2771434 142827..144128 1 NC_005823.1 hypothetical protein 144128 2771434 LIC10122 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000118.1 142827 D 267671 CDS YP_000119.1 45656033 2772832 144198..145190 1 NC_005823.1 hypothetical protein 145190 2772832 LIC10123 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000119.1 144198 D 267671 CDS YP_000120.1 45656034 2772083 145301..146956 1 NC_005823.1 hypothetical protein 146956 2772083 LIC10124 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000120.1 145301 D 267671 CDS YP_000121.1 45656035 2771922 146953..150546 1 NC_005823.1 internal repeat sequences detected; contains TPR domain as detected by pfam-hmmr; hypothetical protein 150546 2771922 LIC10125 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000121.1 146953 D 267671 CDS YP_000122.1 45656036 2771316 complement(151273..151926) 1 NC_005823.1 hypothetical protein 151926 2771316 LIC10126 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000122.1 151273 R 267671 CDS YP_000123.1 45656037 2772566 151976..152914 1 NC_005823.1 hypothetical protein 152914 2772566 LIC10127 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000123.1 151976 D 267671 CDS YP_000124.1 45656038 2770633 153042..153389 1 NC_005823.1 hypothetical protein 153389 2770633 LIC10128 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000124.1 153042 D 267671 CDS YP_000125.1 45656039 2769905 153505..154173 1 NC_005823.1 hypothetical protein 154173 2769905 LIC10129 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000125.1 153505 D 267671 CDS YP_000126.1 45656040 2770363 complement(154396..155049) 1 NC_005823.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 155049 engB 2770363 engB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribosome biogenesis GTP-binding protein YsxC YP_000126.1 154396 R 267671 CDS YP_000127.1 45656041 2771663 complement(155046..156347) 1 NC_005823.1 cell cycle protein 156347 mesJ 2771663 mesJ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cell cycle protein YP_000127.1 155046 R 267671 CDS YP_000128.1 45656042 2769849 157135..159234 1 NC_005823.1 sigma 54 activator 159234 2769849 LIC10132 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sigma 54 activator YP_000128.1 157135 D 267671 CDS YP_000129.1 45656043 2772785 complement(159692..159928) 1 NC_005823.1 hypothetical protein 159928 2772785 LIC10133 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000129.1 159692 R 267671 CDS YP_000130.1 45656044 2771415 159908..161134 1 NC_005823.1 hypothetical protein 161134 2771415 LIC10134 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000130.1 159908 D 267671 CDS YP_000131.1 45656045 2770880 complement(161123..161521) 1 NC_005823.1 SET domain-containing protein 161521 2770880 LIC10135 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 SET domain-containing protein YP_000131.1 161123 R 267671 CDS YP_000132.1 45656046 2771782 complement(161575..163395) 1 NC_005823.1 ABC transporter ATP-binding protein 163395 2771782 LIC10136 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_000132.1 161575 R 267671 CDS YP_000133.1 45656047 2772528 163667..164182 1 NC_005823.1 [protein-PII] uridylyltransferase 164182 2772528 LIC10137 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 [protein-PII] uridylyltransferase YP_000133.1 163667 D 267671 CDS YP_000134.1 45656048 2769550 164349..165818 1 NC_005823.1 HD-GYP hydrolase domain-containing protein 165818 2769550 LIC10138 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 HD-GYP hydrolase domain-containing protein YP_000134.1 164349 D 267671 CDS YP_000135.1 45656049 2772208 166929..168440 1 NC_005823.1 hypothetical protein 168440 2772208 LIC10139 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000135.1 166929 D 267671 CDS YP_000136.1 45656050 2769848 168502..169644 1 NC_005823.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 169644 aroC 2769848 aroC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chorismate synthase YP_000136.1 168502 D 267671 CDS YP_000137.1 45656051 2769964 170447..171895 1 NC_005823.1 NADH dehydrogenase subunit I G 171895 nuoG 2769964 nuoG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH dehydrogenase subunit I G YP_000137.1 170447 D 267671 CDS YP_000138.1 45656052 2771157 171882..172409 1 NC_005823.1 NADH dehydrogenase II subunit 172409 nuoI 2771157 nuoI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH dehydrogenase II subunit YP_000138.1 171882 D 267671 CDS YP_000139.1 45656053 2770275 complement(172832..173080) 1 NC_005823.1 hypothetical protein 173080 2770275 LIC10143 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000139.1 172832 R 267671 CDS YP_000140.1 45656054 2771311 173425..173949 1 NC_005823.1 RNA polymerase ECF-type sigma factor 173949 2771311 LIC10144 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA polymerase ECF-type sigma factor YP_000140.1 173425 D 267671 CDS YP_000141.1 45656055 2772047 173959..175332 1 NC_005823.1 hypothetical protein 175332 2772047 LIC10145 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000141.1 173959 D 267671 CDS YP_000142.1 45656056 2771483 176195..176380 1 NC_005823.1 hypothetical protein 176380 2771483 LIC10146 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000142.1 176195 D 267671 CDS YP_000143.1 45656057 2771981 177952..178608 1 NC_005823.1 polyketide synthase 178608 frnE 2771981 frnE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 polyketide synthase YP_000143.1 177952 D 267671 CDS YP_000144.2 161621780 2769860 179798..181051 1 NC_005823.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 181051 avtA 2769860 avtA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 valine--pyruvate transaminase YP_000144.2 179798 D 267671 CDS YP_000145.1 45656059 2770034 181127..183481 1 NC_005823.1 hypothetical protein 183481 2770034 LIC10151 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000145.1 181127 D 267671 CDS YP_000146.1 45656060 2770132 183950..184201 1 NC_005823.1 hypothetical protein 184201 2770132 LIC10152 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000146.1 183950 D 267671 CDS YP_000147.1 45656061 2771825 184688..184849 1 NC_005823.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 184849 rpmH 2771825 rpmH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L34 YP_000147.1 184688 D 267671 CDS YP_000148.1 45656062 2769862 185176..185400 1 NC_005823.1 hypothetical protein 185400 2769862 LIC10156 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000148.1 185176 D 267671 CDS YP_000149.1 45656063 2770021 185410..187293 1 NC_005823.1 hypothetical protein 187293 2770021 LIC10157 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000149.1 185410 D 267671 CDS YP_000150.1 45656064 2771060 187325..188035 1 NC_005823.1 hypothetical protein 188035 2771060 LIC10158 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000150.1 187325 D 267671 CDS YP_000151.1 45656065 2771935 188028..189398 1 NC_005823.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 189398 trmE 2771935 trmE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tRNA modification GTPase TrmE YP_000151.1 188028 D 267671 CDS YP_000152.1 45656066 2772836 189395..190708 1 NC_005823.1 malic enzyme 190708 maeB 2772836 maeB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 malic enzyme YP_000152.1 189395 D 267671 CDS YP_000153.1 45656067 2772456 191388..193487 1 NC_005823.1 hypothetical protein 193487 2772456 LIC10161 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000153.1 191388 D 267671 CDS YP_000154.1 45656068 2771729 193574..194968 1 NC_005823.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 194968 fumC 2771729 fumC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 fumarate hydratase YP_000154.1 193574 D 267671 CDS YP_000155.1 45656069 2770498 complement(195475..195915) 1 NC_005823.1 hypothetical protein 195915 2770498 LIC10163 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000155.1 195475 R 267671 CDS YP_000156.1 45656070 2771686 complement(195938..196135) 1 NC_005823.1 hypothetical protein 196135 2771686 LIC10164 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000156.1 195938 R 267671 CDS YP_000157.1 45656071 2772496 complement(196365..196787) 1 NC_005823.1 hypothetical protein 196787 2772496 LIC10165 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000157.1 196365 R 267671 CDS YP_000158.1 45656072 2769978 complement(196982..197449) 1 NC_005823.1 hypothetical protein 197449 2769978 LIC10166 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000158.1 196982 R 267671 CDS YP_003858659.1 304570507 9714939 complement(197456..197635) 1 NC_005823.1 hypothetical protein 197635 9714939 LIC14000 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003858659.1 197456 R 267671 CDS YP_000159.1 45656073 2771785 complement(197666..197971) 1 NC_005823.1 hypothetical protein 197971 2771785 LIC10167 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000159.1 197666 R 267671 CDS YP_000160.1 45656074 2771545 198377..198775 1 NC_005823.1 hypothetical protein 198775 2771545 LIC10168 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000160.1 198377 D 267671 CDS YP_000161.1 45656075 2770785 199526..199828 1 NC_005823.1 hypothetical protein 199828 2770785 LIC10169 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000161.1 199526 D 267671 CDS YP_000162.1 45656076 2771517 200018..200251 1 NC_005823.1 hypothetical protein 200251 2771517 LIC10170 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000162.1 200018 D 267671 CDS YP_000163.1 45656077 2769837 200248..200574 1 NC_005823.1 hypothetical protein 200574 2769837 LIC10171 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000163.1 200248 D 267671 CDS YP_000164.1 45656078 2770388 200616..201197 1 NC_005823.1 hypothetical protein 201197 2770388 LIC10172 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000164.1 200616 D 267671 CDS YP_000165.1 45656079 2769886 202322..202936 1 NC_005823.1 hypothetical protein 202936 2769886 LIC10173 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000165.1 202322 D 267671 CDS YP_000166.1 45656080 2772826 202933..203169 1 NC_005823.1 hypothetical protein 203169 2772826 LIC10174 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000166.1 202933 D 267671 CDS YP_000167.1 45656081 2770834 203246..204733 1 NC_005823.1 hypothetical protein 204733 2770834 LIC10175 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000167.1 203246 D 267671 CDS YP_000168.1 45656082 2771439 204743..205177 1 NC_005823.1 hypothetical protein 205177 2771439 LIC10176 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000168.1 204743 D 267671 CDS YP_000169.1 45656083 2771946 205214..205633 1 NC_005823.1 hypothetical protein 205633 2771946 LIC10177 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000169.1 205214 D 267671 CDS YP_000170.1 45656084 2769845 208015..208560 1 NC_005823.1 hypothetical protein 208560 2769845 LIC10179 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000170.1 208015 D 267671 CDS YP_000171.1 45656085 2770625 208557..208928 1 NC_005823.1 hypothetical protein 208928 2770625 LIC10180 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000171.1 208557 D 267671 CDS YP_000172.1 45656086 2771337 208928..209959 1 NC_005823.1 hypothetical protein 209959 2771337 LIC10181 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000172.1 208928 D 267671 CDS YP_000173.1 45656087 2769908 209971..210543 1 NC_005823.1 hypothetical protein 210543 2769908 LIC10182 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000173.1 209971 D 267671 CDS YP_000174.1 45656088 2770133 210543..210905 1 NC_005823.1 hypothetical protein 210905 2770133 LIC10183 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000174.1 210543 D 267671 CDS YP_000175.1 45656089 2770672 211136..212266 1 NC_005823.1 hypothetical protein 212266 2770672 LIC10184 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000175.1 211136 D 267671 CDS YP_000176.1 45656090 2770153 212250..212924 1 NC_005823.1 hypothetical protein 212924 2770153 LIC10185 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000176.1 212250 D 267671 CDS YP_000177.1 45656091 2770046 212990..213712 1 NC_005823.1 hypothetical protein 213712 2770046 LIC10186 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000177.1 212990 D 267671 CDS YP_000178.1 45656092 2771476 213705..215216 1 NC_005823.1 hypothetical protein 215216 2771476 LIC10187 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000178.1 213705 D 267671 CDS YP_000179.1 45656093 2769875 215772..215960 1 NC_005823.1 hypothetical protein 215960 2769875 LIC10188 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000179.1 215772 D 267671 CDS YP_000180.1 45656094 2772204 216137..217693 1 NC_005823.1 hypothetical protein 217693 2772204 LIC10189 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000180.1 216137 D 267671 CDS YP_000181.1 45656095 2770305 218744..220423 1 NC_005823.1 hypothetical protein 220423 2770305 LIC10190 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000181.1 218744 D 267671 CDS YP_000182.1 45656096 2770358 complement(220760..221347) 1 NC_005823.1 OmpA-like; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 221347 2770358 LIC10191 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000182.1 220760 R 267671 CDS YP_000183.1 45656097 2771155 221483..222421 1 NC_005823.1 hypothetical protein 222421 2771155 LIC10192 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000183.1 221483 D 267671 CDS YP_000184.1 45656098 2771177 complement(222390..223232) 1 NC_005823.1 hypothetical protein 223232 2771177 LIC10193 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000184.1 222390 R 267671 CDS YP_000185.1 45656099 2772065 complement(223315..224067) 1 NC_005823.1 short-chain dehydrogenase 224067 2772065 LIC10194 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 short-chain dehydrogenase YP_000185.1 223315 R 267671 CDS YP_000186.1 45656100 2772098 complement(224064..225101) 1 NC_005823.1 photoproduct lyase 225101 splB 2772098 splB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 photoproduct lyase YP_000186.1 224064 R 267671 CDS YP_000187.1 45656101 2771779 complement(225073..225948) 1 NC_005823.1 hypothetical protein 225948 2771779 LIC10196 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000187.1 225073 R 267671 CDS YP_000188.1 45656102 2771164 225977..226339 1 NC_005823.1 hypothetical protein 226339 2771164 LIC10197 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000188.1 225977 D 267671 CDS YP_000189.1 45656103 2770385 226336..227151 1 NC_005823.1 inositol monophosphatase 227151 suhB 2770385 suhB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 inositol monophosphatase YP_000189.1 226336 D 267671 CDS YP_000190.1 45656104 2769892 complement(227461..228795) 1 NC_005823.1 glycosyltransferase 228795 2769892 LIC10199 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyltransferase YP_000190.1 227461 R 267671 CDS YP_000191.1 45656105 2769949 complement(228779..229828) 1 NC_005823.1 glycosyltransferase 229828 2769949 LIC10200 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyltransferase YP_000191.1 228779 R 267671 CDS YP_000192.1 45656106 2771250 complement(229825..230883) 1 NC_005823.1 glycosyl transferase 230883 2771250 LIC10201 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyl transferase YP_000192.1 229825 R 267671 CDS YP_000193.1 45656107 2769515 complement(230880..231890) 1 NC_005823.1 hypothetical protein 231890 2769515 LIC10202 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000193.1 230880 R 267671 CDS YP_000194.1 45656108 2772465 231970..232935 1 NC_005823.1 oxidoreductase 232935 rmd 2772465 rmd Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 oxidoreductase YP_000194.1 231970 D 267671 CDS YP_000195.1 45656109 2769474 complement(233941..234810) 1 NC_005823.1 cytochrome C oxidase assembly protein 234810 cyoE 2769474 cyoE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytochrome C oxidase assembly protein YP_000195.1 233941 R 267671 CDS YP_000196.1 45656110 2769649 complement(234829..235776) 1 NC_005823.1 cytochrome oxidase assembly protein 235776 ctaA 2769649 ctaA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytochrome oxidase assembly protein YP_000196.1 234829 R 267671 CDS YP_000197.1 45656111 2772822 235975..236178 1 NC_005823.1 hypothetical protein 236178 2772822 LIC10206 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000197.1 235975 D 267671 CDS YP_000198.1 45656112 2769944 236204..237043 1 NC_005823.1 SCO1/SenC family protein 237043 2769944 LIC10207 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 SCO1/SenC family protein YP_000198.1 236204 D 267671 CDS YP_000199.1 45656113 2771253 237054..238055 1 NC_005823.1 cytochrome c oxidase polypeptide II 238055 cyoA 2771253 cyoA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytochrome c oxidase polypeptide II YP_000199.1 237054 D 267671 CDS YP_000200.1 45656114 2772775 238066..239670 1 NC_005823.1 cytochrome c oxidase polypeptide I 239670 cyoB 2772775 cyoB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytochrome c oxidase polypeptide I YP_000200.1 238066 D 267671 CDS YP_000201.1 45656115 2771697 239657..240301 1 NC_005823.1 cytochrome/quinol oxidase subunit 3 240301 cyoC 2771697 cyoC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytochrome/quinol oxidase subunit 3 YP_000201.1 239657 D 267671 CDS YP_000202.1 45656116 2772468 241835..242134 1 NC_005823.1 hypothetical protein 242134 2772468 LIC10211 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000202.1 241835 D 267671 CDS YP_000203.1 45656117 2772394 complement(242628..242831) 1 NC_005823.1 hypothetical protein 242831 2772394 LIC10212 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000203.1 242628 R 267671 CDS YP_000204.1 45656118 2772803 243009..243473 1 NC_005823.1 hypothetical protein 243473 2772803 LIC10213 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000204.1 243009 D 267671 CDS YP_000205.1 45656119 2769980 243511..244104 1 NC_005823.1 CarD transcriptional regulator 244104 2769980 LIC10214 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 CarD transcriptional regulator YP_000205.1 243511 D 267671 CDS YP_000206.1 45656120 2769895 244146..245177 1 NC_005823.1 hypothetical protein 245177 2769895 LIC10215 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000206.1 244146 D 267671 CDS YP_000207.1 45656121 2772203 245239..246831 1 NC_005823.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 246831 pckA 2772203 pckA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoenolpyruvate carboxykinase YP_000207.1 245239 D 267671 CDS YP_000208.1 45656122 2770958 complement(247431..247658) 1 NC_005823.1 hypothetical protein 247658 2770958 LIC10217 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000208.1 247431 R 267671 CDS YP_000209.1 45656123 2770995 complement(247666..248406) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 248406 2770995 LIC10218 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000209.1 247666 R 267671 CDS YP_000210.1 45656124 2769940 complement(248443..249258) 1 NC_005823.1 hypothetical protein 249258 2769940 LIC10219 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000210.1 248443 R 267671 CDS YP_000211.1 45656125 2771216 complement(249230..250006) 1 NC_005823.1 hypothetical protein 250006 2771216 LIC10220 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000211.1 249230 R 267671 CDS YP_000212.1 45656126 2771851 250120..251580 1 NC_005823.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 251580 gatB 2771851 gatB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_000212.1 250120 D 267671 CDS YP_000213.1 45656127 2771939 252892..256413 1 NC_005823.1 DNA polymerase III subunit alpha 256413 dnaE 2771939 dnaE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA polymerase III subunit alpha YP_000213.1 252892 D 267671 CDS YP_000214.1 45656128 2771553 complement(256512..256715) 1 NC_005823.1 hypothetical protein 256715 2771553 LIC10223 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000214.1 256512 R 267671 CDS YP_000215.1 45656129 2771706 complement(257388..258287) 1 NC_005823.1 hypothetical protein 258287 2771706 LIC10224 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000215.1 257388 R 267671 CDS YP_000216.1 45656130 2769631 258325..259230 1 NC_005823.1 RNA polymerase ECF-type sigma factor 259230 2769631 LIC10225 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA polymerase ECF-type sigma factor YP_000216.1 258325 D 267671 CDS YP_000217.1 45656131 2769527 259266..259994 1 NC_005823.1 hypothetical protein 259994 2769527 LIC10226 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000217.1 259266 D 267671 CDS YP_000218.1 45656132 2771347 260138..261967 1 NC_005823.1 hypothetical protein 261967 2771347 LIC10227 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000218.1 260138 D 267671 CDS YP_000219.1 45656133 2769540 261972..262658 1 NC_005823.1 hypothetical protein 262658 2769540 LIC10228 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000219.1 261972 D 267671 CDS YP_000221.1 45656135 2769739 complement(265193..266197) 1 NC_005823.1 hypothetical protein 266197 2769739 LIC10230 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000221.1 265193 R 267671 CDS YP_000222.1 45656136 2770274 complement(266210..267223) 1 NC_005823.1 hypothetical protein 267223 2770274 LIC10231 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000222.1 266210 R 267671 CDS YP_000223.1 45656137 2769560 267347..268723 1 NC_005823.1 lipoprotein releasing system transmembrane protein 268723 lolE 2769560 lolE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein releasing system transmembrane protein YP_000223.1 267347 D 267671 CDS YP_000224.1 45656138 2772346 268725..269402 1 NC_005823.1 ABC transporter ATP-binding protein 269402 lolD 2772346 lolD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_000224.1 268725 D 267671 CDS YP_000225.1 45656139 2769677 complement(270472..271200) 1 NC_005823.1 hypothetical protein 271200 2769677 LIC10234 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000225.1 270472 R 267671 CDS YP_000226.1 45656140 2771683 271675..271959 1 NC_005823.1 hypothetical protein 271959 2771683 LIC10235 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000226.1 271675 D 267671 CDS YP_000227.1 45656141 2769684 272177..272815 1 NC_005823.1 hypothetical protein 272815 2769684 LIC10236 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000227.1 272177 D 267671 CDS YP_000228.1 45656142 2772649 272901..274118 1 NC_005823.1 cyclic nucleotide binding protein 274118 2772649 LIC10237 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cyclic nucleotide binding protein YP_000228.1 272901 D 267671 CDS YP_000229.1 45656143 2772705 274139..274825 1 NC_005823.1 3-methyladenine DNA glycosylase 274825 2772705 LIC10238 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-methyladenine DNA glycosylase YP_000229.1 274139 D 267671 CDS YP_000230.1 45656144 2770181 275653..276423 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 276423 2770181 LIC10239 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000230.1 275653 D 267671 CDS YP_000231.1 45656145 2771323 276427..277110 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 277110 2771323 LIC10240 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000231.1 276427 D 267671 CDS YP_000232.1 45656146 2771489 277184..277879 1 NC_005823.1 hypothetical protein 277879 2771489 LIC10241 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000232.1 277184 D 267671 CDS YP_000233.1 45656147 2772835 278177..278527 1 NC_005823.1 hypothetical protein 278527 2772835 LIC10242 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000233.1 278177 D 267671 CDS YP_000234.1 45656148 2769985 complement(278562..278795) 1 NC_005823.1 hypothetical protein 278795 2769985 LIC10243 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000234.1 278562 R 267671 CDS YP_000235.1 45656149 2770911 279110..279868 1 NC_005823.1 hypothetical protein 279868 2770911 LIC10244 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000235.1 279110 D 267671 CDS YP_000236.1 45656150 2771017 complement(280557..282458) 1 NC_005823.1 adenylate/guanylate cyclase 282458 2771017 LIC10245 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_000236.1 280557 R 267671 CDS YP_000237.1 45656151 2770600 complement(282553..282738) 1 NC_005823.1 hypothetical protein 282738 2770600 LIC10246 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000237.1 282553 R 267671 CDS YP_000238.1 45656152 2772869 complement(282813..283028) 1 NC_005823.1 hypothetical protein 283028 2772869 LIC10247 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000238.1 282813 R 267671 CDS YP_000239.1 45656153 2771784 283000..283446 1 NC_005823.1 ankyrin 283446 2771784 LIC10248 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ankyrin YP_000239.1 283000 D 267671 CDS YP_000240.1 45656154 2770307 283507..284688 1 NC_005823.1 RNA methyltransferase 284688 2770307 LIC10249 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA methyltransferase YP_000240.1 283507 D 267671 CDS YP_000241.1 45656155 2771813 284666..284893 1 NC_005823.1 hypothetical protein 284893 2771813 LIC10250 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000241.1 284666 D 267671 CDS YP_000242.1 45656156 2770965 complement(285742..288057) 1 NC_005823.1 Rad50-like protein 288057 2770965 LIC10251 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Rad50-like protein YP_000242.1 285742 R 267671 CDS YP_000243.1 45656157 2769888 complement(288059..289144) 1 NC_005823.1 exonuclease 289144 2769888 LIC10252 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 exonuclease YP_000243.1 288059 R 267671 CDS YP_000244.1 45656158 2771120 289714..290967 1 NC_005823.1 alcohol dehydrogenase 290967 2771120 LIC10253 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alcohol dehydrogenase YP_000244.1 289714 D 267671 CDS YP_000245.1 45656159 2770712 complement(291103..291723) 1 NC_005823.1 hypothetical protein 291723 2770712 LIC10254 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000245.1 291103 R 267671 CDS YP_000246.1 45656160 2770290 complement(291725..292657) 1 NC_005823.1 hypothetical protein 292657 2770290 LIC10255 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000246.1 291725 R 267671 CDS YP_000247.1 45656161 2770721 292745..294850 1 NC_005823.1 carbon starvation protein A 294850 2770721 LIC10256 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 carbon starvation protein A YP_000247.1 292745 D 267671 CDS YP_000248.1 45656162 2771516 294847..295395 1 NC_005823.1 MutT/nudix family protein 295395 2771516 LIC10257 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 MutT/nudix family protein YP_000248.1 294847 D 267671 CDS YP_000249.1 45656163 2771921 295703..297472 1 NC_005823.1 hypothetical protein 297472 2771921 LIC10258 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000249.1 295703 D 267671 CDS YP_000250.1 45656164 2771023 297478..298209 1 NC_005823.1 hypothetical protein 298209 2771023 LIC10259 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000250.1 297478 D 267671 CDS YP_000251.1 45656165 2770210 complement(298484..298837) 1 NC_005823.1 lipoprotein 298837 2770210 LIC10260 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000251.1 298484 R 267671 CDS YP_000252.1 45656166 2772345 complement(298834..299175) 1 NC_005823.1 hypothetical protein 299175 2772345 LIC10261 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000252.1 298834 R 267671 CDS YP_000253.1 45656167 2771653 299476..300321 1 NC_005823.1 hypothetical protein 300321 2771653 LIC10262 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000253.1 299476 D 267671 CDS YP_000254.1 45656168 2769913 301007..301402 1 NC_005823.1 transposase, ISlin1 301402 2769913 LIC10263 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_000254.1 301007 D 267671 CDS YP_000255.1 45656169 2770108 301371..301958 1 NC_005823.1 transposase, ISlin1 301958 2770108 LIC10264 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_000255.1 301371 D 267671 CDS YP_000256.1 45656170 2770606 301964..302323 1 NC_005823.1 transposase, ISlin1 302323 2770606 LIC10265 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_000256.1 301964 D 267671 CDS YP_000257.1 45656171 2769734 complement(302883..303743) 1 NC_005823.1 protoporphyrinogen oxidase 303743 hemK 2769734 hemK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 protoporphyrinogen oxidase YP_000257.1 302883 R 267671 CDS YP_000258.1 45656172 2769657 complement(305018..305683) 1 NC_005823.1 cyclic nucleotide binding protein 305683 2769657 LIC10268 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cyclic nucleotide binding protein YP_000258.1 305018 R 267671 CDS YP_000259.1 45656173 2772365 complement(305683..306738) 1 NC_005823.1 cyclic nucleotide binding protein 306738 2772365 LIC10269 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cyclic nucleotide binding protein YP_000259.1 305683 R 267671 CDS YP_000260.1 45656174 2771303 complement(306749..307999) 1 NC_005823.1 chlorohydrolase 307999 2771303 LIC10270 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chlorohydrolase YP_000260.1 306749 R 267671 CDS YP_000261.1 45656175 2772046 complement(308018..308683) 1 NC_005823.1 contains LysM domain; identified by sequence similarity; ORF located using Blastx/Glimmer; cell wall hydrolase 308683 2772046 LIC10271 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cell wall hydrolase YP_000261.1 308018 R 267671 CDS YP_000262.1 45656176 2769723 complement(308932..311052) 1 NC_005823.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 311052 fusA 2769723 fusA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 elongation factor G YP_000262.1 308932 R 267671 CDS YP_000263.1 45656177 2771989 311079..311270 1 NC_005823.1 hypothetical protein 311270 2771989 LIC10273 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000263.1 311079 D 267671 CDS YP_000264.1 45656178 2772196 311339..312958 1 NC_005823.1 potassium uptake protein 312958 2772196 LIC10274 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 potassium uptake protein YP_000264.1 311339 D 267671 CDS YP_000265.1 45656179 2772138 complement(313254..313568) 1 NC_005823.1 hypothetical protein 313568 2772138 LIC10275 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000265.1 313254 R 267671 CDS YP_000266.1 45656180 2770744 complement(314020..314226) 1 NC_005823.1 hypothetical protein 314226 2770744 LIC10276 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000266.1 314020 R 267671 CDS YP_000267.2 161621779 2770640 315261..316160 1 NC_005823.1 catalyzes the formation of decaprenylphosphoryl-5-phosphoribose from phosphoribose diphosphate and decaprenyl phosphate; phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase 316160 2770640 LIC10277 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase YP_000267.2 315261 D 267671 CDS YP_000268.1 45656182 2771601 316875..317378 1 NC_005823.1 thioredoxin-like protein 317378 2771601 LIC10278 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thioredoxin-like protein YP_000268.1 316875 D 267671 CDS YP_000269.1 45656183 2772285 318164..318934 1 NC_005823.1 hypothetical protein 318934 2772285 LIC10279 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000269.1 318164 D 267671 CDS YP_000270.1 45656184 2770914 complement(319105..319524) 1 NC_005823.1 hypothetical protein 319524 2770914 LIC10280 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000270.1 319105 R 267671 CDS YP_000271.1 45656185 2769924 320113..320553 1 NC_005823.1 hypothetical protein 320553 2769924 LIC10281 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000271.1 320113 D 267671 CDS YP_000272.1 45656186 2772575 321233..322255 1 NC_005823.1 zinc-binding dehydrogenase family protein 322255 2772575 LIC10282 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 zinc-binding dehydrogenase family protein YP_000272.1 321233 D 267671 CDS YP_000273.1 45656187 2772481 322520..323518 1 NC_005823.1 geranyltranstransferase; farnesyl-diphosphate synthase 323518 ispA 2772481 ispA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 farnesyl-diphosphate synthase YP_000273.1 322520 D 267671 CDS YP_000274.1 45656188 2770650 323499..324278 1 NC_005823.1 hemolysin A 324278 tlyA 2770650 tlyA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hemolysin A YP_000274.1 323499 D 267671 CDS YP_000275.1 45656189 2770892 324481..325707 1 NC_005823.1 acetyltransferase 325707 2770892 LIC10285 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyltransferase YP_000275.1 324481 D 267671 CDS YP_000276.1 45656190 2771593 complement(326098..328614) 1 NC_005823.1 penicillin G acylase precursor 328614 paC 2771593 paC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 penicillin G acylase precursor YP_000276.1 326098 R 267671 CDS YP_000277.1 45656191 2771990 330129..330515 1 NC_005823.1 6-pyruvoyl tetrahydrobiopterin synthase 330515 ptpS 2771990 ptpS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 6-pyruvoyl tetrahydrobiopterin synthase YP_000277.1 330129 D 267671 CDS YP_000278.1 45656192 2770610 330525..331253 1 NC_005823.1 hypothetical protein 331253 2770610 LIC10288 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000278.1 330525 D 267671 CDS YP_000279.1 45656193 2769703 331331..331615 1 NC_005823.1 proton-translocating transhydrogenase subunit alpha 2 331615 2769703 LIC10289 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 proton-translocating transhydrogenase subunit alpha 2 YP_000279.1 331331 D 267671 CDS YP_000280.1 45656194 2769909 331618..333018 1 NC_005823.1 H+-translocating transhydrogenase subunit beta 333018 2769909 LIC10290 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 H+-translocating transhydrogenase subunit beta YP_000280.1 331618 D 267671 CDS YP_000281.1 45656195 2769764 334521..335024 1 NC_005823.1 hypothetical protein 335024 2769764 LIC10291 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000281.1 334521 D 267671 CDS YP_000282.1 45656196 2772476 335410..335682 1 NC_005823.1 hypothetical protein 335682 2772476 LIC10292 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000282.1 335410 D 267671 CDS YP_000283.1 45656197 2769617 complement(335804..336799) 1 NC_005823.1 glycerophosphoryl diester phosphodiesterase 336799 glpQ 2769617 glpQ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycerophosphoryl diester phosphodiesterase YP_000283.1 335804 R 267671 CDS YP_000284.1 45656198 2769763 338060..338548 1 NC_005823.1 GlcG 338548 glcG 2769763 glcG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GlcG YP_000284.1 338060 D 267671 CDS YP_000285.1 45656199 2769646 complement(339340..339747) 1 NC_005823.1 hypothetical protein 339747 2769646 LIC10295 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000285.1 339340 R 267671 CDS YP_000286.1 45656200 2769506 340411..340596 1 NC_005823.1 hypothetical protein 340596 2769506 LIC10296 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000286.1 340411 D 267671 CDS YP_000287.1 45656201 2769605 complement(340569..340952) 1 NC_005823.1 forms a junction between the M-ring and FlgB during the flagella biosynthesis; flagellar hook-basal body protein FliE 340952 fliE 2769605 fliE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar hook-basal body protein FliE YP_000287.1 340569 R 267671 CDS YP_000288.1 45656202 2770185 complement(340955..341422) 1 NC_005823.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 341422 flgC 2770185 flgC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar basal body rod protein FlgC YP_000288.1 340955 R 267671 CDS YP_000289.1 45656203 2771400 complement(341482..341913) 1 NC_005823.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgB 341913 flgB 2771400 flgB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar basal body rod protein FlgB YP_000289.1 341482 R 267671 CDS YP_000290.1 45656204 2770062 342035..342325 1 NC_005823.1 anti-sigma factor antagonist 342325 2770062 LIC10300 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_000290.1 342035 D 267671 CDS YP_000291.1 45656205 2772547 342722..343063 1 NC_005823.1 lipoprotein 343063 2772547 LIC10301 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000291.1 342722 D 267671 CDS YP_000292.1 45656206 2770612 343096..344145 1 NC_005823.1 internal repeat sequences detected; contains TPR domain as detected by pfam-hmmr; hypothetical protein 344145 2770612 LIC10302 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000292.1 343096 D 267671 CDS YP_000293.1 45656207 2770858 344343..345584 1 NC_005823.1 hypothetical protein 345584 2770858 LIC10303 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000293.1 344343 D 267671 CDS YP_000294.1 45656208 2769931 complement(345674..346156) 1 NC_005823.1 hypothetical protein 346156 2769931 LIC10304 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000294.1 345674 R 267671 CDS YP_000295.1 45656209 2770170 complement(346176..346370) 1 NC_005823.1 hypothetical protein 346370 2770170 LIC10305 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000295.1 346176 R 267671 CDS YP_000296.1 45656210 2770654 complement(346549..346929) 1 NC_005823.1 hypothetical protein 346929 2770654 LIC10306 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000296.1 346549 R 267671 CDS YP_000297.1 45656211 2770051 complement(347214..348191) 1 NC_005823.1 lipoprotein 348191 2770051 LIC10307 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000297.1 347214 R 267671 CDS YP_000298.1 45656212 2770889 348837..349532 1 NC_005823.1 hypothetical protein 349532 2770889 LIC10308 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000298.1 348837 D 267671 CDS YP_000299.1 45656213 2770466 complement(350674..353568) 1 NC_005823.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 353568 gcvP 2770466 gcvP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycine dehydrogenase YP_000299.1 350674 R 267671 CDS YP_000300.1 45656214 2770370 complement(353608..354000) 1 NC_005823.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 354000 gcvH 2770370 gcvH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycine cleavage system protein H YP_000300.1 353608 R 267671 CDS YP_000301.2 229259641 2772283 complement(354018..355133) 1 NC_005823.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 355133 gcvT 2772283 gcvT Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycine cleavage system aminomethyltransferase T YP_000301.2 354018 R 267671 CDS YP_000302.1 45656216 2771613 355898..356158 1 NC_005823.1 hypothetical protein 356158 2771613 LIC10312 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000302.1 355898 D 267671 CDS YP_000303.1 45656217 2770657 356592..356969 1 NC_005823.1 hypothetical protein 356969 2770657 LIC10313 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000303.1 356592 D 267671 CDS YP_000304.1 45656218 2772618 complement(357239..358912) 1 NC_005823.1 hypothetical protein 358912 2772618 LIC10314 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000304.1 357239 R 267671 CDS YP_000305.2 161621778 2769680 359072..360163 1 NC_005823.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 360163 serC 2769680 serC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoserine aminotransferase YP_000305.2 359072 D 267671 CDS YP_000306.1 45656220 2770306 360160..360762 1 NC_005823.1 hypothetical protein 360762 2770306 LIC10316 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000306.1 360160 D 267671 CDS YP_000307.1 45656221 2772363 361249..361686 1 NC_005823.1 ribose 5-phosphate isomerase B 361686 rpiB 2772363 rpiB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribose 5-phosphate isomerase B YP_000307.1 361249 D 267671 CDS YP_000308.1 45656222 2771471 361750..363672 1 NC_005823.1 hypothetical protein 363672 2771471 LIC10318 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000308.1 361750 D 267671 CDS YP_000309.1 45656223 2772437 complement(364047..364235) 1 NC_005823.1 hypothetical protein 364235 2772437 LIC10319 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000309.1 364047 R 267671 CDS YP_000310.1 45656224 2772609 complement(364235..364837) 1 NC_005823.1 hypothetical protein 364837 2772609 LIC10320 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000310.1 364235 R 267671 CDS YP_000311.1 45656225 2770383 complement(364857..366947) 1 NC_005823.1 hypothetical protein 366947 2770383 LIC10321 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000311.1 364857 R 267671 CDS YP_000312.1 45656226 2772839 complement(366944..367876) 1 NC_005823.1 hypothetical protein 367876 2772839 LIC10322 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000312.1 366944 R 267671 CDS YP_000313.1 45656227 2772223 367989..368960 1 NC_005823.1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase gene 368960 2772223 LIC10323 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 2,3-bisphosphoglycerate-independent phosphoglycerate mutase gene YP_000313.1 367989 D 267671 CDS YP_000314.1 45656228 2769486 369133..369561 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 369561 2769486 LIC10324 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000314.1 369133 D 267671 CDS YP_000315.1 45656229 2772816 complement(369634..370770) 1 NC_005823.1 contains TPR domains; identified by sequence similarity; ORF located using Blastx/Glimmer; hemolysin 370770 hlyX 2772816 hlyX Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hemolysin YP_000315.1 369634 R 267671 CDS YP_000316.1 45656230 2770677 complement(370767..372341) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 372341 2770677 LIC10326 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000316.1 370767 R 267671 CDS YP_000317.1 45656231 2770010 372539..373333 1 NC_005823.1 hypothetical protein 373333 2770010 LIC10327 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000317.1 372539 D 267671 CDS YP_000318.1 45656232 2771606 complement(373574..373873) 1 NC_005823.1 hypothetical protein 373873 2771606 LIC10328 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000318.1 373574 R 267671 CDS YP_000319.1 45656233 2770217 complement(374075..374977) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 374977 2770217 LIC10329 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000319.1 374075 R 267671 CDS YP_000320.1 45656234 2770794 complement(375054..375635) 1 NC_005823.1 hypothetical protein 375635 2770794 LIC10330 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000320.1 375054 R 267671 CDS YP_000321.1 45656235 2770676 complement(376109..377497) 1 NC_005823.1 sugar transferase 377497 2770676 LIC10331 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sugar transferase YP_000321.1 376109 R 267671 CDS YP_000322.1 45656236 2770542 377576..378337 1 NC_005823.1 response regulator 378337 2770542 LIC10332 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_000322.1 377576 D 267671 CDS YP_000323.1 45656237 2770919 378327..380516 1 NC_005823.1 histidine kinase 380516 2770919 LIC10333 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase YP_000323.1 378327 D 267671 CDS YP_000324.1 45656238 2772241 380519..380842 1 NC_005823.1 hypothetical protein 380842 2772241 LIC10334 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000324.1 380519 D 267671 CDS YP_000325.1 45656239 2771402 380913..381161 1 NC_005823.1 hypothetical protein 381161 2771402 LIC10335 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000325.1 380913 D 267671 CDS YP_000326.1 45656240 2769898 complement(381235..382548) 1 NC_005823.1 hypothetical protein 382548 2769898 LIC10336 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000326.1 381235 R 267671 CDS YP_000327.1 45656241 2771616 complement(382529..383638) 1 NC_005823.1 internal repeat sequences detected; contains TPR domain as detected by pfam-hmmr; hypothetical protein 383638 2771616 LIC10337 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000327.1 382529 R 267671 CDS YP_000328.1 45656242 2770028 complement(383660..384085) 1 NC_005823.1 hypothetical protein 384085 2770028 LIC10338 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000328.1 383660 R 267671 CDS YP_000329.1 45656243 2769881 complement(384088..386628) 1 NC_005823.1 hemolysin B 386628 tlyB 2769881 tlyB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hemolysin B YP_000329.1 384088 R 267671 CDS YP_000330.1 45656244 2771763 complement(386773..387573) 1 NC_005823.1 hypothetical protein 387573 2771763 LIC10340 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000330.1 386773 R 267671 CDS YP_000331.1 45656245 2770312 complement(387955..388140) 1 NC_005823.1 hypothetical protein 388140 2770312 LIC10341 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000331.1 387955 R 267671 CDS YP_000332.1 45656246 2770440 complement(388796..389014) 1 NC_005823.1 hypothetical protein 389014 2770440 LIC10342 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000332.1 388796 R 267671 CDS YP_000333.1 45656247 2771814 389169..389771 1 NC_005823.1 integrase/recombinase 389771 2771814 LIC10343 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 integrase/recombinase YP_000333.1 389169 D 267671 CDS YP_000334.1 45656248 2769910 389836..390102 1 NC_005823.1 anti-sigma factor antagonist 390102 2769910 LIC10344 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_000334.1 389836 D 267671 CDS YP_000335.1 45656249 2771192 390182..391696 1 NC_005823.1 hypothetical protein 391696 2771192 LIC10345 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000335.1 390182 D 267671 CDS YP_000336.1 45656250 2771679 391693..392343 1 NC_005823.1 esterase 392343 2771679 LIC10346 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 esterase YP_000336.1 391693 D 267671 CDS YP_000337.1 45656251 2769962 complement(392987..394048) 1 NC_005823.1 paraoxonase 394048 2769962 LIC10347 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 paraoxonase YP_000337.1 392987 R 267671 CDS YP_000338.1 45656252 2770101 394192..394455 1 NC_005823.1 hypothetical protein 394455 2770101 LIC10348 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000338.1 394192 D 267671 CDS YP_000339.1 45656253 2769505 complement(396320..396802) 1 NC_005823.1 hypothetical protein 396802 2769505 LIC10350 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000339.1 396320 R 267671 CDS YP_000340.1 45656254 2772094 397010..397924 1 NC_005823.1 ABC transporter ATP-binding protein 397924 nosF 2772094 nosF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_000340.1 397010 D 267671 CDS YP_000341.1 45656255 2770790 397917..398741 1 NC_005823.1 hypothetical protein 398741 2770790 LIC10352 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000341.1 397917 D 267671 CDS YP_000342.1 45656256 2769939 398825..400336 1 NC_005823.1 hypothetical protein 400336 2769939 LIC10353 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000342.1 398825 D 267671 CDS YP_000343.1 45656257 2772504 complement(400333..401238) 1 NC_005823.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 401238 ksgA 2772504 ksgA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dimethyladenosine transferase YP_000343.1 400333 R 267671 CDS YP_000344.1 45656258 2769916 complement(401201..403510) 1 NC_005823.1 hypothetical protein 403510 2769916 LIC10355 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000344.1 401201 R 267671 CDS YP_000345.1 45656259 2770844 complement(403566..403763) 1 NC_005823.1 hypothetical protein 403763 2770844 LIC10356 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000345.1 403566 R 267671 CDS YP_000346.1 45656260 2771288 complement(404374..405342) 1 NC_005823.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 405342 trpS 2771288 trpS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tryptophanyl-tRNA synthetase YP_000346.1 404374 R 267671 CDS YP_000347.1 45656261 2772366 complement(405339..407159) 1 NC_005823.1 hypothetical protein 407159 2772366 LIC10358 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000347.1 405339 R 267671 CDS YP_000348.1 45656262 2770041 complement(407165..407758) 1 NC_005823.1 hypothetical protein 407758 2770041 LIC10359 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000348.1 407165 R 267671 CDS YP_000349.1 45656263 2772795 complement(407883..408842) 1 NC_005823.1 electron transfer flavoprotein alpha-subunit 408842 etfA 2772795 etfA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 electron transfer flavoprotein alpha-subunit YP_000349.1 407883 R 267671 CDS YP_000350.1 45656264 2770718 complement(408854..409615) 1 NC_005823.1 electron transport flavoprotein subunit beta 409615 etfB2 2770718 etfB2 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 electron transport flavoprotein subunit beta YP_000350.1 408854 R 267671 CDS YP_000351.1 45656265 2772056 complement(409698..410120) 1 NC_005823.1 hypothetical protein 410120 2772056 LIC10362 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000351.1 409698 R 267671 CDS YP_000352.1 45656266 2772300 410178..411362 1 NC_005823.1 isovaleryl-CoA dehydrogenase 411362 ivd 2772300 ivd Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 isovaleryl-CoA dehydrogenase YP_000352.1 410178 D 267671 CDS YP_000353.1 45656267 2770671 411359..412054 1 NC_005823.1 hypothetical protein 412054 2770671 LIC10364 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000353.1 411359 D 267671 CDS YP_000354.1 45656268 2769744 complement(412116..413195) 1 NC_005823.1 lipoprotein 413195 2769744 LIC10365 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000354.1 412116 R 267671 CDS YP_000355.1 45656269 2770142 complement(414377..414925) 1 NC_005823.1 lipoprotein 414925 2770142 LIC10368 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000355.1 414377 R 267671 CDS YP_000356.1 45656270 2770430 complement(415699..416244) 1 NC_005823.1 hypothetical protein 416244 2770430 LIC10369 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000356.1 415699 R 267671 CDS YP_000357.1 45656271 2770018 complement(416322..416864) 1 NC_005823.1 hypothetical protein 416864 2770018 LIC10370 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000357.1 416322 R 267671 CDS YP_000358.1 45656272 2769970 complement(418037..419479) 1 NC_005823.1 lipoprotein 419479 2769970 LIC10371 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000358.1 418037 R 267671 CDS YP_000359.1 45656273 2770384 complement(421630..423159) 1 NC_005823.1 lipoprotein 423159 2770384 LIC10373 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000359.1 421630 R 267671 CDS YP_000360.1 45656274 2772298 complement(423893..424612) 1 NC_005823.1 hypothetical protein 424612 2772298 LIC10374 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000360.1 423893 R 267671 CDS YP_000361.1 45656275 2770748 complement(424630..425316) 1 NC_005823.1 TetR family transcriptional regulator 425316 2770748 LIC10375 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 TetR family transcriptional regulator YP_000361.1 424630 R 267671 CDS YP_000362.1 45656276 2770175 complement(425325..426215) 1 NC_005823.1 internal repeat sequences detected; contains Ankyryn repeat as detected by pfam-hmmr; hypothetical protein 426215 2770175 LIC10376 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000362.1 425325 R 267671 CDS YP_000363.1 45656277 2770833 427241..427999 1 NC_005823.1 lipoprotein 427999 2770833 LIC10377 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000363.1 427241 D 267671 CDS YP_000364.1 45656278 2772603 429051..429401 1 NC_005823.1 ParR family transcriptional regulator 429401 2772603 LIC10378 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ParR family transcriptional regulator YP_000364.1 429051 D 267671 CDS YP_000365.1 45656279 2770539 429398..429910 1 NC_005823.1 hypothetical protein 429910 2770539 LIC10379 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000365.1 429398 D 267671 CDS YP_000366.1 45656280 2771031 429918..430463 1 NC_005823.1 hypothetical protein 430463 2771031 LIC10380 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000366.1 429918 D 267671 CDS YP_000367.1 45656281 2770464 complement(430830..431036) 1 NC_005823.1 hypothetical protein 431036 2770464 LIC10381 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000367.1 430830 R 267671 CDS YP_000368.1 45656282 2771290 complement(431902..433599) 1 NC_005823.1 acyl-CoA dehydrogenase 433599 2771290 LIC10382 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyl-CoA dehydrogenase YP_000368.1 431902 R 267671 CDS YP_000369.1 45656283 2772361 complement(434195..435853) 1 NC_005823.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 435853 yibO 2772361 yibO Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoglyceromutase YP_000369.1 434195 R 267671 CDS YP_000370.1 45656284 2772659 436231..438249 1 NC_005823.1 hypothetical protein 438249 2772659 LIC10384 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000370.1 436231 D 267671 CDS YP_000371.1 45656285 2769885 complement(438915..439781) 1 NC_005823.1 hypothetical protein 439781 2769885 LIC10385 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000371.1 438915 R 267671 CDS YP_000372.1 45656286 2772792 439864..440412 1 NC_005823.1 RNA polymerase ECF-type sigma factor 440412 2772792 LIC10386 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA polymerase ECF-type sigma factor YP_000372.1 439864 D 267671 CDS YP_000373.1 45656287 2771005 440542..441621 1 NC_005823.1 hypothetical protein 441621 2771005 LIC10387 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000373.1 440542 D 267671 CDS YP_000374.1 45656288 2772134 complement(443205..443669) 1 NC_005823.1 hypothetical protein 443669 2772134 LIC10388 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000374.1 443205 R 267671 CDS YP_003858660.1 304570512 9714938 445019..445144 1 NC_005823.1 hypothetical protein 445144 9714938 LIC14005 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003858660.1 445019 D 267671 CDS YP_000375.1 45656289 2772246 445216..447156 1 NC_005823.1 ABC transporter ATP-binding protein 447156 2772246 LIC10389 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_000375.1 445216 D 267671 CDS YP_000376.1 45656290 2772075 447654..447995 1 NC_005823.1 hypothetical protein 447995 2772075 LIC10390 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000376.1 447654 D 267671 CDS YP_000377.1 45656291 2772610 448480..449316 1 NC_005823.1 hypothetical protein 449316 2772610 LIC10391 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000377.1 448480 D 267671 CDS YP_000378.1 45656292 2769600 complement(450508..450702) 1 NC_005823.1 hypothetical protein 450702 2769600 LIC10392 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000378.1 450508 R 267671 CDS YP_000379.1 45656293 2770982 complement(450744..451022) 1 NC_005823.1 hypothetical protein 451022 2770982 LIC10393 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000379.1 450744 R 267671 CDS YP_000380.1 45656294 2772820 451103..451288 1 NC_005823.1 hypothetical protein 451288 2772820 LIC10394 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000380.1 451103 D 267671 CDS YP_000381.1 45656295 2770741 complement(451514..452125) 1 NC_005823.1 TetR family transcriptional regulator 452125 2770741 LIC10395 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 TetR family transcriptional regulator YP_000381.1 451514 R 267671 CDS YP_000382.1 45656296 2772236 452995..454176 1 NC_005823.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 454176 phbA 2772236 phbA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyl-CoA acetyltransferase YP_000382.1 452995 D 267671 CDS YP_000383.1 45656297 2770929 454287..454577 1 NC_005823.1 hypothetical protein 454577 2770929 LIC10397 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000383.1 454287 D 267671 CDS YP_000384.1 45656298 2770293 complement(454818..456149) 1 NC_005823.1 hypothetical protein 456149 2770293 LIC10398 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000384.1 454818 R 267671 CDS YP_000385.1 45656299 2771542 complement(456146..456727) 1 NC_005823.1 hypothetical protein 456727 2771542 LIC10399 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000385.1 456146 R 267671 CDS YP_000386.1 45656300 2772184 457309..458136 1 NC_005823.1 hypothetical protein 458136 2772184 LIC10400 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000386.1 457309 D 267671 CDS YP_000387.1 45656301 2769773 458140..458859 1 NC_005823.1 hypothetical protein 458859 2769773 LIC10401 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000387.1 458140 D 267671 CDS YP_000388.1 45656302 2771134 complement(458994..459800) 1 NC_005823.1 hypothetical protein 459800 2771134 LIC10402 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000388.1 458994 R 267671 CDS YP_000389.1 45656303 2770338 459910..460365 1 NC_005823.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 460365 ribH 2770338 ribH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 6,7-dimethyl-8-ribityllumazine synthase YP_000389.1 459910 D 267671 CDS YP_000390.1 45656304 2770092 460402..460782 1 NC_005823.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 460782 nusB 2770092 nusB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transcription antitermination protein NusB YP_000390.1 460402 D 267671 CDS YP_000391.1 45656305 2771212 460775..462841 1 NC_005823.1 internal repeat sequences detected; contains TPR domain as detected by pfam-hmmr; hypothetical protein 462841 2771212 LIC10405 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000391.1 460775 D 267671 CDS YP_000392.1 45656306 2772721 462862..464178 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 464178 2772721 LIC10406 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000392.1 462862 D 267671 CDS YP_000393.1 45656307 2770083 complement(464770..465624) 1 NC_005823.1 hypothetical protein 465624 2770083 LIC10407 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000393.1 464770 R 267671 CDS YP_000394.1 45656308 2772635 complement(466325..466507) 1 NC_005823.1 hypothetical protein 466507 2772635 LIC10408 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000394.1 466325 R 267671 CDS YP_000395.1 45656309 2770787 466921..468207 1 NC_005823.1 2-isopropylmalate synthase 468207 2770787 LIC10409 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 2-isopropylmalate synthase YP_000395.1 466921 D 267671 CDS YP_000396.1 45656310 2770045 complement(468215..468400) 1 NC_005823.1 hypothetical protein 468400 2770045 LIC10410 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000396.1 468215 R 267671 CDS YP_000397.1 45656311 2770487 complement(468646..469119) 1 NC_005823.1 hypothetical protein 469119 2770487 LIC10411 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000397.1 468646 R 267671 CDS YP_000398.1 45656312 2772267 469667..469864 1 NC_005823.1 hypothetical protein 469864 2772267 LIC10412 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000398.1 469667 D 267671 CDS YP_000399.1 45656313 2772066 469881..471041 1 NC_005823.1 hypothetical protein 471041 2772066 LIC10413 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000399.1 469881 D 267671 CDS YP_000400.1 45656314 2772270 472108..473565 1 NC_005823.1 hypothetical protein 473565 2772270 LIC10414 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000400.1 472108 D 267671 CDS YP_000401.1 45656315 2770866 complement(473977..474495) 1 NC_005823.1 hypothetical protein 474495 2770866 LIC10415 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000401.1 473977 R 267671 CDS YP_000402.1 45656316 2771615 474831..475049 1 NC_005823.1 hypothetical protein 475049 2771615 LIC10416 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000402.1 474831 D 267671 CDS YP_000403.1 45656317 2771049 475423..475668 1 NC_005823.1 hypothetical protein 475668 2771049 LIC10417 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000403.1 475423 D 267671 CDS YP_000404.1 45656318 2772748 complement(475685..475915) 1 NC_005823.1 hypothetical protein 475915 2772748 LIC10418 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000404.1 475685 R 267671 CDS YP_000405.2 304570486 2770125 475870..476916 1 NC_005823.1 hypothetical protein 476916 2770125 LIC10419 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000405.2 475870 D 267671 CDS YP_000406.1 45656320 2770755 complement(478459..479760) 1 NC_005823.1 DNA helicase II 479760 2770755 LIC10420 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA helicase II YP_000406.1 478459 R 267671 CDS YP_000407.1 45656321 2772548 481710..482045 1 NC_005823.1 hypothetical protein 482045 2772548 LIC10421 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000407.1 481710 D 267671 CDS YP_000408.1 45656322 2770735 complement(482399..482668) 1 NC_005823.1 hypothetical protein 482668 2770735 LIC10422 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000408.1 482399 R 267671 CDS YP_000409.1 45656323 2771786 complement(483153..483767) 1 NC_005823.1 hypothetical protein 483767 2771786 LIC10423 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000409.1 483153 R 267671 CDS YP_000410.1 45656324 2770443 complement(483777..485222) 1 NC_005823.1 hypothetical protein 485222 2770443 LIC10424 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000410.1 483777 R 267671 CDS YP_000411.1 45656325 2770851 486553..487497 1 NC_005823.1 hypothetical protein 487497 2770851 LIC10425 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000411.1 486553 D 267671 CDS YP_000412.1 45656326 2770030 488013..488906 1 NC_005823.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 488906 ispE 2770030 ispE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_000412.1 488013 D 267671 CDS YP_000413.1 45656327 2769746 489012..489770 1 NC_005823.1 UDP-N-acetylglucosamine pyrophosphorylase 489770 glmU 2769746 glmU Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-N-acetylglucosamine pyrophosphorylase YP_000413.1 489012 D 267671 CDS YP_000414.1 45656328 2771013 489767..490705 1 NC_005823.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 490705 prs 2771013 prs Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribose-phosphate pyrophosphokinase YP_000414.1 489767 D 267671 CDS YP_000415.1 45656329 2770382 490723..491361 1 NC_005823.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 491361 rplY 2770382 rplY Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L25/general stress protein Ctc YP_000415.1 490723 D 267671 CDS YP_000416.1 45656330 2770660 491408..491971 1 NC_005823.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 491971 2770660 LIC10431 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peptidyl-tRNA hydrolase YP_000416.1 491408 D 267671 CDS YP_000417.1 45656331 2770332 492131..494098 1 NC_005823.1 cell division protein 494098 ftsH 2770332 ftsH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cell division protein YP_000417.1 492131 D 267671 CDS YP_000418.1 45656332 2771580 494095..494565 1 NC_005823.1 hypothetical protein 494565 2771580 LIC10433 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000418.1 494095 D 267671 CDS YP_000419.1 45656333 2770739 complement(495350..495715) 1 NC_005823.1 hypothetical protein 495715 2770739 LIC10434 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000419.1 495350 R 267671 CDS YP_000420.1 45656334 2770483 496279..496782 1 NC_005823.1 hypothetical protein 496782 2770483 LIC10435 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000420.1 496279 D 267671 CDS YP_000421.1 45656335 2771504 497272..497490 1 NC_005823.1 hypothetical protein 497490 2771504 LIC10436 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000421.1 497272 D 267671 CDS YP_000422.1 45656336 2771021 complement(497527..499023) 1 NC_005823.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 499023 2771021 LIC10437 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 spermidine synthase YP_000422.1 497527 R 267671 CDS YP_000423.1 45656337 2769660 complement(499031..499225) 1 NC_005823.1 hypothetical protein 499225 2769660 LIC10438 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000423.1 499031 R 267671 CDS YP_000424.1 45656338 2769513 complement(499782..501815) 1 NC_005823.1 hypothetical protein 501815 2769513 LIC10439 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000424.1 499782 R 267671 CDS YP_000425.1 45656339 2771019 complement(502348..502692) 1 NC_005823.1 nitrogen regulatory protein PII 502692 glnB 2771019 glnB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 nitrogen regulatory protein PII YP_000425.1 502348 R 267671 CDS YP_000426.1 45656340 2770796 complement(502731..504023) 1 NC_005823.1 ammonium transporter 504023 2770796 LIC10441 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ammonium transporter YP_000426.1 502731 R 267671 CDS YP_000427.1 45656341 2771130 complement(504073..504279) 1 NC_005823.1 hypothetical protein 504279 2771130 LIC10442 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000427.1 504073 R 267671 CDS YP_000428.1 45656342 2772303 complement(505348..506958) 1 NC_005823.1 3-methylcrotonoyl-CoA carboxylase subunit beta 506958 mccB 2772303 mccB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-methylcrotonoyl-CoA carboxylase subunit beta YP_000428.1 505348 R 267671 CDS YP_000429.1 45656343 2770409 complement(506975..508021) 1 NC_005823.1 glucose-1-phosphate thymidylyltransferase 508021 2770409 LIC10444 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glucose-1-phosphate thymidylyltransferase YP_000429.1 506975 R 267671 CDS YP_000430.1 45656344 2771712 complement(508027..509859) 1 NC_005823.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 509859 glmS 2771712 glmS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glucosamine--fructose-6-phosphate aminotransferase YP_000430.1 508027 R 267671 CDS YP_000431.1 45656345 2772354 complement(509862..511244) 1 NC_005823.1 phosphomannomutase 511244 2772354 LIC10446 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphomannomutase YP_000431.1 509862 R 267671 CDS YP_000432.1 45656346 2770870 complement(511364..511630) 1 NC_005823.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 511630 rpsT 2770870 rpsT Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S20 YP_000432.1 511364 R 267671 CDS YP_000433.1 45656347 2769943 512321..512791 1 NC_005823.1 hypothetical protein 512791 2769943 LIC10449 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000433.1 512321 D 267671 CDS YP_000434.1 45656348 2772209 512791..513861 1 NC_005823.1 hypothetical protein 513861 2772209 LIC10450 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000434.1 512791 D 267671 CDS YP_000435.1 45656349 2770575 513874..514665 1 NC_005823.1 hypothetical protein 514665 2770575 LIC10451 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000435.1 513874 D 267671 CDS YP_000436.1 45656350 2770289 514668..515363 1 NC_005823.1 glycosyltransferase 515363 2770289 LIC10452 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyltransferase YP_000436.1 514668 D 267671 CDS YP_000437.1 45656351 2770700 complement(516363..517454) 1 NC_005823.1 hypothetical protein 517454 2770700 LIC10453 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000437.1 516363 R 267671 CDS YP_000438.1 45656352 2769543 complement(517537..518316) 1 NC_005823.1 hypothetical protein 518316 2769543 LIC10454 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000438.1 517537 R 267671 CDS YP_000439.1 45656353 2770751 518601..518852 1 NC_005823.1 hypothetical protein 518852 2770751 LIC10455 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000439.1 518601 D 267671 CDS YP_000440.1 45656354 2770322 complement(519271..519720) 1 NC_005823.1 hypothetical protein 519720 2770322 LIC10456 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000440.1 519271 R 267671 CDS YP_000441.1 45656355 2770447 complement(519798..520592) 1 NC_005823.1 hypothetical protein 520592 2770447 LIC10457 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000441.1 519798 R 267671 CDS YP_000442.1 45656356 2772389 complement(520953..521804) 1 NC_005823.1 hypothetical protein 521804 2772389 LIC10458 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000442.1 520953 R 267671 CDS YP_000443.1 45656357 2771224 523243..524571 1 NC_005823.1 adenosine deaminase 524571 add 2771224 add Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenosine deaminase YP_000443.1 523243 D 267671 CDS YP_000444.1 45656358 2770019 524825..525229 1 NC_005823.1 hypothetical protein 525229 2770019 LIC10460 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000444.1 524825 D 267671 CDS YP_000445.1 45656359 2771099 complement(525211..525549) 1 NC_005823.1 lipoprotein 525549 2771099 LIC10461 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000445.1 525211 R 267671 CDS YP_000446.1 45656360 2770353 complement(525559..525939) 1 NC_005823.1 hypothetical protein 525939 2770353 LIC10462 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000446.1 525559 R 267671 CDS YP_000447.1 45656361 2772295 complement(525914..526393) 1 NC_005823.1 lipoprotein 526393 2772295 LIC10463 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000447.1 525914 R 267671 CDS YP_000448.1 45656362 2771118 complement(526395..532067) 1 NC_005823.1 Big; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 532067 ligB 2771118 ligB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000448.1 526395 R 267671 CDS YP_000449.1 45656363 2771127 complement(533414..537088) 1 NC_005823.1 Big; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 537088 ligA 2771127 ligA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000449.1 533414 R 267671 CDS YP_000450.1 45656364 2771971 complement(537545..537928) 1 NC_005823.1 hypothetical protein 537928 2771971 LIC10466 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000450.1 537545 R 267671 CDS YP_000451.1 45656365 2770279 complement(539373..539564) 1 NC_005823.1 hypothetical protein 539564 2770279 LIC10467 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000451.1 539373 R 267671 CDS YP_000452.1 45656366 2770454 complement(540177..540950) 1 NC_005823.1 hypothetical protein 540950 2770454 LIC10468 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000452.1 540177 R 267671 CDS YP_000453.1 45656367 2771131 complement(541013..541723) 1 NC_005823.1 hypothetical protein 541723 2771131 LIC10469 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000453.1 541013 R 267671 CDS YP_000454.1 45656368 2771964 complement(541840..542943) 1 NC_005823.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 542943 prfB 2771964 prfB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peptide chain release factor 2 YP_000454.1 541840 R 267671 CDS YP_000455.1 45656369 2770667 complement(543822..544667) 1 NC_005823.1 hypothetical protein 544667 2770667 LIC10471 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000455.1 543822 R 267671 CDS YP_000456.1 45656370 2771801 complement(544669..545949) 1 NC_005823.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 545949 purD 2771801 purD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoribosylamine--glycine ligase YP_000456.1 544669 R 267671 CDS YP_000457.1 45656371 2770473 complement(545939..548587) 1 NC_005823.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 548587 valS 2770473 valS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 valyl-tRNA synthetase YP_000457.1 545939 R 267671 CDS YP_000458.1 45656372 2770273 complement(548766..549194) 1 NC_005823.1 hypothetical protein 549194 2770273 LIC10474 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000458.1 548766 R 267671 CDS YP_000459.1 45656373 2769958 complement(550361..550621) 1 NC_005823.1 RNA-binding protein 550621 2769958 LIC10475 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA-binding protein YP_000459.1 550361 R 267671 CDS YP_000460.1 45656374 2770940 complement(550654..550899) 1 NC_005823.1 hypothetical protein 550899 2770940 LIC10476 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000460.1 550654 R 267671 CDS YP_000461.1 45656375 2771286 550946..551551 1 NC_005823.1 hypothetical protein 551551 2771286 LIC10477 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000461.1 550946 D 267671 CDS YP_000462.1 45656376 2772601 complement(552136..552732) 1 NC_005823.1 SPase I; identified by sequence similarity; ORF located using Blastx/Glimmer; signal peptidase I 552732 lepB 2772601 lepB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 signal peptidase I YP_000462.1 552136 R 267671 CDS YP_000463.1 45656377 2772024 complement(552776..554374) 1 NC_005823.1 hypothetical protein 554374 2772024 LIC10479 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000463.1 552776 R 267671 CDS YP_000464.1 45656378 2771734 complement(555303..556838) 1 NC_005823.1 hypothetical protein 556838 2771734 LIC10480 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000464.1 555303 R 267671 CDS YP_000465.1 45656379 2770250 complement(557180..558775) 1 NC_005823.1 hypothetical protein 558775 2770250 LIC10481 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000465.1 557180 R 267671 CDS YP_000466.1 45656380 2772147 559027..559608 1 NC_005823.1 hypothetical protein 559608 2772147 LIC10482 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000466.1 559027 D 267671 CDS YP_000467.1 45656381 2772537 559699..560691 1 NC_005823.1 hypothetical protein 560691 2772537 LIC10483 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000467.1 559699 D 267671 CDS YP_000468.1 45656382 2770984 560695..562044 1 NC_005823.1 threonine synthase 562044 thrC 2770984 thrC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 threonine synthase YP_000468.1 560695 D 267671 CDS YP_000469.1 45656383 2769887 562549..563274 1 NC_005823.1 hypothetical protein 563274 2769887 LIC10485 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000469.1 562549 D 267671 CDS YP_000470.1 45656384 2770436 563286..564359 1 NC_005823.1 hypothetical protein 564359 2770436 LIC10486 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000470.1 563286 D 267671 CDS YP_000471.1 45656385 2771299 564763..565245 1 NC_005823.1 hypothetical protein 565245 2771299 LIC10487 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000471.1 564763 D 267671 CDS YP_000472.1 45656386 2772329 complement(565275..565970) 1 NC_005823.1 hypothetical protein 565970 2772329 LIC10488 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000472.1 565275 R 267671 CDS YP_000473.1 45656387 2771518 complement(565967..566692) 1 NC_005823.1 internal repeat sequences detected; contains MORN repeat as detected by pfam-hmmr; hypothetical protein 566692 2771518 LIC10489 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000473.1 565967 R 267671 CDS YP_000474.1 45656388 2772849 complement(566667..569582) 1 NC_005823.1 acriflavine resistance 569582 2772849 LIC10490 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acriflavine resistance YP_000474.1 566667 R 267671 CDS YP_000475.1 45656389 2772906 complement(569594..572674) 1 NC_005823.1 acriflavin resistance 572674 acrB 2772906 acrB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acriflavin resistance YP_000475.1 569594 R 267671 CDS YP_000476.1 45656390 2772093 complement(572671..574164) 1 NC_005823.1 heavy metal efflux pump 574164 2772093 LIC10492 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heavy metal efflux pump YP_000476.1 572671 R 267671 CDS YP_000477.1 45656391 2769740 complement(574511..575152) 1 NC_005823.1 hypothetical protein 575152 2769740 LIC10493 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000477.1 574511 R 267671 CDS YP_000478.1 45656392 2771762 complement(575154..575849) 1 NC_005823.1 lipoprotein 575849 2771762 LIC10494 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000478.1 575154 R 267671 CDS YP_000479.1 45656393 2769800 complement(575873..577699) 1 NC_005823.1 contains internal repeat sequence; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 577699 2769800 LIC10495 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000479.1 575873 R 267671 CDS YP_000480.1 45656394 2771847 complement(577711..579240) 1 NC_005823.1 hypothetical protein 579240 2771847 LIC10496 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000480.1 577711 R 267671 CDS YP_000481.1 45656395 2770757 579686..582883 1 NC_005823.1 internal repeat sequences detected; hypothetical protein 582883 2770757 LIC10497 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000481.1 579686 D 267671 CDS YP_000482.1 45656396 2770174 583441..586308 1 NC_005823.1 lipoprotein 586308 2770174 LIC10498 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000482.1 583441 D 267671 CDS YP_000483.1 45656397 2772629 586849..587388 1 NC_005823.1 outer membrane protein 587388 2772629 LIC10499 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 outer membrane protein YP_000483.1 586849 D 267671 CDS YP_000484.1 45656398 2771276 587952..588434 1 NC_005823.1 hypothetical protein 588434 2771276 LIC10500 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000484.1 587952 D 267671 CDS YP_000485.1 45656399 2771403 588652..590184 1 NC_005823.1 lipoprotein 590184 2771403 LIC10501 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000485.1 588652 D 267671 CDS YP_000486.1 45656400 2770628 590325..598688 1 NC_005823.1 hypothetical protein 598688 2770628 LIC10502 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000486.1 590325 D 267671 CDS YP_003858661.1 304570511 9714931 598786..599316 1 NC_005823.1 hypothetical protein 599316 9714931 LIC14004 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003858661.1 598786 D 267671 CDS YP_000487.1 45656401 2772723 complement(599481..600833) 1 NC_005823.1 transposase, IS3 600833 2772723 LIC10503 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, IS3 YP_000487.1 599481 R 267671 CDS YP_000488.1 45656402 2771776 600973..601719 1 NC_005823.1 hypothetical protein 601719 2771776 LIC10504 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000488.1 600973 D 267671 CDS YP_000489.1 45656403 2771744 601854..602831 1 NC_005823.1 nuclease-like protein 602831 2771744 LIC10505 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 nuclease-like protein YP_000489.1 601854 D 267671 CDS YP_000490.1 45656404 2769716 602964..605069 1 NC_005823.1 hypothetical protein 605069 2769716 LIC10506 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000490.1 602964 D 267671 CDS YP_000491.1 45656405 2769628 605069..605704 1 NC_005823.1 lipoprotein 605704 2769628 LIC10507 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000491.1 605069 D 267671 CDS YP_000492.1 45656406 2772135 605726..606337 1 NC_005823.1 lipoprotein 606337 2772135 LIC10508 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000492.1 605726 D 267671 CDS YP_000493.1 45656407 2770111 606359..606967 1 NC_005823.1 lipoprotein 606967 2770111 LIC10509 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000493.1 606359 D 267671 CDS YP_000494.1 45656408 2770639 607847..614539 1 NC_005823.1 hypothetical protein 614539 2770639 LIC10510 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000494.1 607847 D 267671 CDS YP_000495.1 45656409 2771849 614543..615793 1 NC_005823.1 hypothetical protein 615793 2771849 LIC10511 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000495.1 614543 D 267671 CDS YP_000496.1 45656410 2771251 615803..616642 1 NC_005823.1 hypothetical protein 616642 2771251 LIC10512 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000496.1 615803 D 267671 CDS YP_000497.1 45656411 2770549 complement(617188..618138) 1 NC_005823.1 transposase, IS3 618138 2770549 LIC10513 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, IS3 YP_000497.1 617188 R 267671 CDS YP_000498.1 45656412 2772753 618386..618586 1 NC_005823.1 hypothetical protein 618586 2772753 LIC10514 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000498.1 618386 D 267671 CDS YP_000499.1 45656413 2770506 618721..619155 1 NC_005823.1 hypothetical protein 619155 2770506 LIC10515 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000499.1 618721 D 267671 CDS YP_000500.1 45656414 2769659 complement(619250..619579) 1 NC_005823.1 hypothetical protein 619579 2769659 LIC10516 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000500.1 619250 R 267671 CDS YP_000501.1 45656415 2769941 complement(621063..623654) 1 NC_005823.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 623654 leuS 2769941 leuS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 leucyl-tRNA synthetase YP_000501.1 621063 R 267671 CDS YP_003858662.1 304570513 9714934 complement(623663..623830) 1 NC_005823.1 hypothetical protein 623830 9714934 LIC14006 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003858662.1 623663 R 267671 CDS YP_000502.1 45656416 2772315 624124..624915 1 NC_005823.1 ABC transporter ATP-binding protein 624915 2772315 LIC10518 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_000502.1 624124 D 267671 CDS YP_000503.1 45656417 2771203 624912..627449 1 NC_005823.1 hypothetical protein 627449 2771203 LIC10519 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000503.1 624912 D 267671 CDS YP_000504.1 45656418 2771289 complement(627768..628052) 1 NC_005823.1 hypothetical protein 628052 2771289 LIC10520 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000504.1 627768 R 267671 CDS YP_000505.1 45656419 2770325 complement(628614..629162) 1 NC_005823.1 hypothetical protein 629162 2770325 LIC10521 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000505.1 628614 R 267671 CDS YP_000506.1 45656420 2769846 complement(629186..630154) 1 NC_005823.1 oxidoreductase family protein 630154 2769846 LIC10522 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 oxidoreductase family protein YP_000506.1 629186 R 267671 CDS YP_000507.1 45656421 2770935 complement(630440..631558) 1 NC_005823.1 molecular chaperone; chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 631558 dnaJ 2770935 dnaJ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chaperone protein DnaJ YP_000507.1 630440 R 267671 CDS YP_000508.1 45656422 2769897 complement(631859..633799) 1 NC_005823.1 heat shock protein 70; heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 633799 dnaK 2769897 dnaK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 molecular chaperone DnaK YP_000508.1 631859 R 267671 CDS YP_000509.1 45656423 2771883 complement(633834..634472) 1 NC_005823.1 molecular chaperone; with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 634472 grpE 2771883 grpE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heat shock protein GrpE YP_000509.1 633834 R 267671 CDS YP_000510.1 45656424 2770147 complement(634486..635514) 1 NC_005823.1 heat-inducible transcriptional repressor 635514 hrcA 2770147 hrcA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heat-inducible transcriptional repressor YP_000510.1 634486 R 267671 CDS YP_000511.1 45656425 2772142 complement(636772..637398) 1 NC_005823.1 arsenate reductase 637398 arsC 2772142 arsC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 arsenate reductase YP_000511.1 636772 R 267671 CDS YP_000512.1 45656426 2770768 637791..639599 1 NC_005823.1 penicillin-binding protein 3; Pbp3 639599 pbpB 2770768 pbpB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Pbp3 YP_000512.1 637791 D 267671 CDS YP_000513.1 45656427 2769788 639618..641762 1 NC_005823.1 hypothetical protein 641762 2769788 LIC10529 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000513.1 639618 D 267671 CDS YP_000514.1 45656428 2770972 complement(642231..642731) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 642731 2770972 LIC10530 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000514.1 642231 R 267671 CDS YP_000515.1 45656429 2770426 complement(643645..644688) 1 NC_005823.1 tetraacyldisaccharide 4'-kinase 644688 lpxK 2770426 lpxK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tetraacyldisaccharide 4'-kinase YP_000515.1 643645 R 267671 CDS YP_000516.1 45656430 2770478 complement(644712..646592) 1 NC_005823.1 ABC transporter ATP-binding protein 646592 2770478 LIC10532 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_000516.1 644712 R 267671 CDS YP_000517.1 45656431 2772763 646592..648151 1 NC_005823.1 peptide ABC transporter substrate-binding protein 648151 dbp 2772763 dbp Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peptide ABC transporter substrate-binding protein YP_000517.1 646592 D 267671 CDS YP_000518.1 45656432 2770098 complement(648129..650537) 1 NC_005823.1 penicillin-binding protein 1 650537 pbp1 2770098 pbp1 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 penicillin-binding protein 1 YP_000518.1 648129 R 267671 CDS YP_000519.1 45656433 2771241 complement(650889..651689) 1 NC_005823.1 hypothetical protein 651689 2771241 LIC10535 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000519.1 650889 R 267671 CDS YP_000520.1 45656434 2772702 651919..652131 1 NC_005823.1 hypothetical protein 652131 2772702 LIC10536 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000520.1 651919 D 267671 CDS YP_000521.1 45656435 2771723 complement(653295..655277) 1 NC_005823.1 OmpA-like; identified by sequence similarity; ORF located using Blastx/Glimmer; peptidoglycan associated periplasmic protein 655277 2771723 LIC10537 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peptidoglycan associated periplasmic protein YP_000521.1 653295 R 267671 CDS YP_000522.1 45656436 2772364 655378..657012 1 NC_005823.1 ABC transporter ATP-binding protein 657012 ybiT 2772364 ybiT Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_000522.1 655378 D 267671 CDS YP_000523.1 45656437 2771534 658301..659638 1 NC_005823.1 hypothetical protein 659638 2771534 LIC10539 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000523.1 658301 D 267671 CDS YP_000524.1 45656438 2769691 complement(659620..659940) 1 NC_005823.1 hypothetical protein 659940 2769691 LIC10540 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000524.1 659620 R 267671 CDS YP_000525.1 45656439 2770349 complement(660943..661599) 1 NC_005823.1 acetyltransferase 661599 vatB 2770349 vatB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyltransferase YP_000525.1 660943 R 267671 CDS YP_000526.1 45656440 2772245 661832..662026 1 NC_005823.1 hypothetical protein 662026 2772245 LIC10542 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000526.1 661832 D 267671 CDS YP_000527.1 45656441 2769965 complement(663201..664916) 1 NC_005823.1 acyl-CoA dehydrogenase 664916 2769965 LIC10543 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyl-CoA dehydrogenase YP_000527.1 663201 R 267671 CDS YP_000528.1 45656442 2770737 665500..666870 1 NC_005823.1 transmembrane; identified by sequence similarity; ORF located using Blastx/Glimmer; outer membrane protein 666870 2770737 LIC10544 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 outer membrane protein YP_000528.1 665500 D 267671 CDS YP_000529.1 45656443 2770769 667284..667847 1 NC_005823.1 peptide methionine sulfoxide reductase 667847 2770769 LIC10545 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peptide methionine sulfoxide reductase YP_000529.1 667284 D 267671 CDS YP_000530.1 45656444 2772020 668074..669147 1 NC_005823.1 lipase 669147 2772020 LIC10546 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipase YP_000530.1 668074 D 267671 CDS YP_000531.1 45656445 2772707 669535..670578 1 NC_005823.1 lipoprotein 670578 2772707 LIC10547 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000531.1 669535 D 267671 CDS YP_000532.1 45656446 2770378 complement(670544..671200) 1 NC_005823.1 uracil-DNA glycosylase 671200 2770378 LIC10548 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 uracil-DNA glycosylase YP_000532.1 670544 R 267671 CDS YP_000533.1 45656447 2772736 complement(672486..673079) 1 NC_005823.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 673079 2772736 LIC10549 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 deoxyribonucleotide triphosphate pyrophosphatase YP_000533.1 672486 R 267671 CDS YP_000534.1 45656448 2770932 complement(673076..673543) 1 NC_005823.1 anti-sigma factor antagonist 673543 2770932 LIC10550 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_000534.1 673076 R 267671 CDS YP_000535.1 45656449 2771361 674264..675379 1 NC_005823.1 hypothetical protein 675379 2771361 LIC10551 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000535.1 674264 D 267671 CDS YP_000536.1 45656450 2770156 complement(675814..677904) 1 NC_005823.1 response regulator hybrid protein; histidine kinase 677904 2770156 LIC10552 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase YP_000536.1 675814 R 267671 CDS YP_000537.1 45656451 2771590 complement(677905..678705) 1 NC_005823.1 alpha/beta hydrolase fold family; identified by sequence similarity; ORF located using Blastx/Glimmer; hydrolase 678705 2771590 LIC10553 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hydrolase YP_000537.1 677905 R 267671 CDS YP_000538.1 45656452 2772030 complement(678930..679424) 1 NC_005823.1 hypothetical protein 679424 2772030 LIC10554 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000538.1 678930 R 267671 CDS YP_000539.1 45656453 2771381 679732..680166 1 NC_005823.1 hypothetical protein 680166 2771381 LIC10555 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000539.1 679732 D 267671 CDS YP_000540.1 45656454 2770730 680157..680447 1 NC_005823.1 hypothetical protein 680447 2770730 LIC10556 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000540.1 680157 D 267671 CDS YP_000541.1 45656455 2772542 681980..682663 1 NC_005823.1 response regulator 682663 2772542 LIC10557 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_000541.1 681980 D 267671 CDS YP_000542.1 45656456 2772612 684092..684532 1 NC_005823.1 hypothetical protein 684532 2772612 LIC10558 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000542.1 684092 D 267671 CDS YP_000543.1 45656457 2770674 684522..685067 1 NC_005823.1 RNA polymerase ECF-type sigma factor 685067 2770674 LIC10559 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA polymerase ECF-type sigma factor YP_000543.1 684522 D 267671 CDS YP_000544.1 45656458 2771778 685057..685320 1 NC_005823.1 hypothetical protein 685320 2771778 LIC10560 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000544.1 685057 D 267671 CDS YP_000545.1 45656459 2771143 686735..687625 1 NC_005823.1 hypothetical protein 687625 2771143 LIC10561 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000545.1 686735 D 267671 CDS YP_000546.1 45656460 2772453 687612..688169 1 NC_005823.1 lipoprotein 688169 2772453 LIC10562 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000546.1 687612 D 267671 CDS YP_000547.1 45656461 2770270 689171..689947 1 NC_005823.1 hypothetical protein; identified by sequence similarity; ORF located using Blastx/Glimmer; SenC 689947 senC 2770270 senC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 SenC YP_000547.1 689171 D 267671 CDS YP_000548.1 45656462 2772446 690659..691012 1 NC_005823.1 single-strand DNA-binding protein 691012 2772446 LIC10564 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 single-strand DNA-binding protein YP_000548.1 690659 D 267671 CDS YP_000549.1 45656463 2770770 691320..692123 1 NC_005823.1 enoyl-CoA hydratase 692123 hbd1 2770770 hbd1 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 enoyl-CoA hydratase YP_000549.1 691320 D 267671 CDS YP_000550.1 45656464 2769990 complement(692332..692526) 1 NC_005823.1 hypothetical protein 692526 2769990 LIC10566 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000550.1 692332 R 267671 CDS YP_000551.1 45656465 2770812 692685..692873 1 NC_005823.1 hypothetical protein 692873 2770812 LIC10567 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000551.1 692685 D 267671 CDS YP_000552.1 45656466 2772582 693096..693839 1 NC_005823.1 hypothetical protein 693839 2772582 LIC10568 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000552.1 693096 D 267671 CDS YP_000553.1 45656467 2772562 complement(693905..694444) 1 NC_005823.1 hypothetical protein 694444 2772562 LIC10569 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000553.1 693905 R 267671 CDS YP_000554.1 45656468 2770602 complement(695312..695686) 1 NC_005823.1 anti-sigma factor antagonist 695686 2770602 LIC10570 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_000554.1 695312 R 267671 CDS YP_000555.1 45656469 2772177 complement(695784..697073) 1 NC_005823.1 homoserine dehydrogenase 697073 hom 2772177 hom Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 homoserine dehydrogenase YP_000555.1 695784 R 267671 CDS YP_000556.1 45656470 2769972 697215..697826 1 NC_005823.1 hypothetical protein 697826 2769972 LIC10572 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000556.1 697215 D 267671 CDS YP_000557.1 45656471 2769907 699190..699399 1 NC_005823.1 IS1533 transposase 699399 2769907 LIC10573 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 IS1533 transposase YP_000557.1 699190 D 267671 CDS YP_000558.1 45656472 2770335 699396..700670 1 NC_005823.1 dihydroorotase 700670 pyrC 2770335 pyrC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dihydroorotase YP_000558.1 699396 D 267671 CDS YP_000559.1 45656473 2771180 complement(700823..701017) 1 NC_005823.1 hypothetical protein 701017 2771180 LIC10575 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000559.1 700823 R 267671 CDS YP_000560.1 45656474 2770620 complement(701450..703006) 1 NC_005823.1 protease modulator; GTP-binding protein 703006 hflX 2770620 hflX Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GTP-binding protein YP_000560.1 701450 R 267671 CDS YP_000561.1 45656475 2771010 703094..703324 1 NC_005823.1 hypothetical protein 703324 2771010 LIC10577 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000561.1 703094 D 267671 CDS YP_000562.1 45656476 2770534 703367..704827 1 NC_005823.1 hypothetical protein 704827 2770534 LIC10578 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000562.1 703367 D 267671 CDS YP_000563.1 45656477 2770188 complement(704816..705229) 1 NC_005823.1 response regulator 705229 2770188 LIC10579 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_000563.1 704816 R 267671 CDS YP_000564.1 45656478 2772451 complement(705226..707121) 1 NC_005823.1 ABC transporter ATP-binding protein 707121 2772451 LIC10580 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_000564.1 705226 R 267671 CDS YP_000565.1 45656479 2770129 complement(707118..707696) 1 NC_005823.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 707696 trpG 2770129 trpG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anthranilate synthase component II YP_000565.1 707118 R 267671 CDS YP_000566.1 45656480 2772195 complement(707696..709117) 1 NC_005823.1 anthranilate synthase component I 709117 trpE 2772195 trpE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anthranilate synthase component I YP_000566.1 707696 R 267671 CDS YP_000567.1 45656481 2771651 complement(709204..710517) 1 NC_005823.1 acyl-CoA dehydrogenase 710517 2771651 LIC10583 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyl-CoA dehydrogenase YP_000567.1 709204 R 267671 CDS YP_000568.1 45656482 2770850 710535..710783 1 NC_005823.1 hypothetical protein 710783 2770850 LIC10584 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000568.1 710535 D 267671 CDS YP_000569.1 45656483 2770817 complement(710820..711059) 1 NC_005823.1 hypothetical protein 711059 2770817 LIC10585 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000569.1 710820 R 267671 CDS YP_000570.1 45656484 2772148 complement(711562..714315) 1 NC_005823.1 DNA polymerase I 714315 polA 2772148 polA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA polymerase I YP_000570.1 711562 R 267671 CDS YP_000571.1 45656485 2770518 complement(714312..715418) 1 NC_005823.1 glycosyl transferase 715418 2770518 LIC10587 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyl transferase YP_000571.1 714312 R 267671 CDS YP_000572.1 45656486 2772788 716324..717100 1 NC_005823.1 glutamine amidotransferase 717100 yafJ 2772788 yafJ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutamine amidotransferase YP_000572.1 716324 D 267671 CDS YP_000573.1 45656487 2772565 717451..719907 1 NC_005823.1 ammonium transporter 719907 amt3 2772565 amt3 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ammonium transporter YP_000573.1 717451 D 267671 CDS YP_000574.1 45656488 2771932 complement(721185..722018) 1 NC_005823.1 hypothetical protein 722018 2771932 LIC10590 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000574.1 721185 R 267671 CDS YP_000575.1 45656489 2772377 complement(722043..722363) 1 NC_005823.1 periplasmic divalent cation tolerance 722363 cutA 2772377 cutA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 periplasmic divalent cation tolerance YP_000575.1 722043 R 267671 CDS YP_000576.1 45656490 2770983 722430..723857 1 NC_005823.1 OmpA-like; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 723857 2770983 LIC10592 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000576.1 722430 D 267671 CDS YP_000577.1 45656491 2769858 724062..726671 1 NC_005823.1 hypothetical protein 726671 2769858 LIC10593 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000577.1 724062 D 267671 CDS YP_000578.1 45656492 2770441 726776..727822 1 NC_005823.1 catalyzes the formation of 2-dehydropantoate from (R)-pantoate; 2-dehydropantoate 2-reductase 727822 panE2 2770441 panE2 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 2-dehydropantoate 2-reductase YP_000578.1 726776 D 267671 CDS YP_000579.1 45656493 2771242 727898..728116 1 NC_005823.1 hypothetical protein 728116 2771242 LIC10595 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000579.1 727898 D 267671 CDS YP_000580.1 45656494 2770182 complement(728943..729707) 1 NC_005823.1 lipoprotein 729707 2770182 LIC10596 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000580.1 728943 R 267671 CDS YP_000581.1 45656495 2770632 complement(730390..730692) 1 NC_005823.1 hypothetical protein 730692 2770632 LIC10597 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000581.1 730390 R 267671 CDS YP_000582.1 45656496 2772101 730692..732746 1 NC_005823.1 hypothetical protein 732746 2772101 LIC10598 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000582.1 730692 D 267671 CDS YP_000583.1 45656497 2771371 complement(732816..733493) 1 NC_005823.1 hypothetical protein 733493 2771371 LIC10599 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000583.1 732816 R 267671 CDS YP_000584.1 45656498 2771748 complement(733931..734347) 1 NC_005823.1 fatty acid synthase subunit beta 734347 2771748 LIC10600 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 fatty acid synthase subunit beta YP_000584.1 733931 R 267671 CDS YP_000585.1 45656499 2772206 complement(734349..734801) 1 NC_005823.1 hypothetical protein 734801 2772206 LIC10601 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000585.1 734349 R 267671 CDS YP_000586.1 45656500 2772871 complement(734918..735847) 1 NC_005823.1 lysophospholipase 735847 pldB 2772871 pldB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lysophospholipase YP_000586.1 734918 R 267671 CDS YP_000587.1 45656501 2770329 735961..738324 1 NC_005823.1 sulfatase family protein 738324 2770329 LIC10603 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sulfatase family protein YP_000587.1 735961 D 267671 CDS YP_000588.1 45656502 2771264 739456..739959 1 NC_005823.1 hypothetical protein 739959 2771264 LIC10604 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000588.1 739456 D 267671 CDS YP_000589.1 45656503 2769852 740627..741025 1 NC_005823.1 hypothetical protein 741025 2769852 LIC10605 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000589.1 740627 D 267671 CDS YP_000590.1 45656504 2772583 complement(741539..742057) 1 NC_005823.1 DNA-binding stress protein 742057 dps 2772583 dps Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA-binding stress protein YP_000590.1 741539 R 267671 CDS YP_000591.1 45656505 2771485 complement(742538..743662) 1 NC_005823.1 degT family; identified by sequence similarity; ORF located using Blastx/Glimmer; aminotransferase 743662 2771485 LIC10607 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aminotransferase YP_000591.1 742538 R 267671 CDS YP_000592.1 45656506 2771277 complement(743707..746226) 1 NC_005823.1 ATP-dependent protease La 746226 lon 2771277 lon Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent protease La YP_000592.1 743707 R 267671 CDS YP_000593.1 45656507 2771032 747407..747886 1 NC_005823.1 internal repeat sequences detected; contains TPR domain as detected by pfam-hmmr; hypothetical protein 747886 2771032 LIC10609 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000593.1 747407 D 267671 CDS YP_000594.1 45656508 2771101 748327..748812 1 NC_005823.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 748812 ispF 2771101 ispF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_000594.1 748327 D 267671 CDS YP_000595.1 45656509 2771478 749410..749661 1 NC_005823.1 hypothetical protein 749661 2771478 LIC10611 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000595.1 749410 D 267671 CDS YP_000596.1 45656510 2772878 complement(750258..750707) 1 NC_005823.1 ribosomal protein S18 acetyltransferase 750707 2772878 LIC10612 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribosomal protein S18 acetyltransferase YP_000596.1 750258 R 267671 CDS YP_000597.1 45656511 2772297 750846..751193 1 NC_005823.1 hypothetical protein 751193 2772297 LIC10613 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000597.1 750846 D 267671 CDS YP_000598.1 45656512 2770067 752971..753189 1 NC_005823.1 hypothetical protein 753189 2770067 LIC10614 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000598.1 752971 D 267671 CDS YP_000599.1 45656513 2772883 753194..754192 1 NC_005823.1 lipoprotein 754192 2772883 LIC10615 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000599.1 753194 D 267671 CDS YP_000600.1 45656514 2772895 754189..755172 1 NC_005823.1 DNA processing chain A 755172 2772895 LIC10616 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA processing chain A YP_000600.1 754189 D 267671 CDS YP_000601.1 45656515 2769668 755192..756640 1 NC_005823.1 gamma-glutamyl carboxylase-like protein 756640 2769668 LIC10617 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 gamma-glutamyl carboxylase-like protein YP_000601.1 755192 D 267671 CDS YP_000602.1 45656516 2769693 complement(756959..757732) 1 NC_005823.1 hypothetical protein 757732 2769693 LIC10618 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000602.1 756959 R 267671 CDS YP_000603.1 45656517 2772949 758373..758891 1 NC_005823.1 hypothetical protein 758891 2772949 LIC10619 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000603.1 758373 D 267671 CDS YP_000604.1 45656518 2769583 759056..760156 1 NC_005823.1 glycosyl transferase 760156 2769583 LIC10620 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyl transferase YP_000604.1 759056 D 267671 CDS YP_000605.1 45656519 2769710 760161..760385 1 NC_005823.1 flagellar protein 760385 flbD 2769710 flbD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar protein YP_000605.1 760161 D 267671 CDS YP_000606.1 45656520 2769669 760391..761173 1 NC_005823.1 motility protein A 761173 motA 2769669 motA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 motility protein A YP_000606.1 760391 D 267671 CDS YP_000607.1 45656521 2769477 761189..762016 1 NC_005823.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 762016 motB 2769477 motB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar motor protein MotB YP_000607.1 761189 D 267671 CDS YP_000608.1 45656522 2769751 762057..762581 1 NC_005823.1 flagellar protein 762581 fliL 2769751 fliL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar protein YP_000608.1 762057 D 267671 CDS YP_000609.1 45656523 2769815 762578..763324 1 NC_005823.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 763324 kdsB 2769815 kdsB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-deoxy-manno-octulosonate cytidylyltransferase YP_000609.1 762578 D 267671 CDS YP_000610.1 45656524 2772899 complement(764267..764605) 1 NC_005823.1 anti-sigma factor antagonist 764605 2772899 LIC10626 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_000610.1 764267 R 267671 CDS YP_000611.1 45656525 2769536 complement(764654..764872) 1 NC_005823.1 hypothetical protein 764872 2769536 LIC10627 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000611.1 764654 R 267671 CDS YP_000612.1 45656526 2769623 complement(764960..765379) 1 NC_005823.1 lipoprotein 765379 2769623 LIC10628 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000612.1 764960 R 267671 CDS YP_000613.1 45656527 2772326 complement(766917..768464) 1 NC_005823.1 glycerol kinase 768464 glpK2 2772326 glpK2 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycerol kinase YP_000613.1 766917 R 267671 CDS YP_000614.1 45656528 2772885 complement(769429..769869) 1 NC_005823.1 hypothetical protein 769869 2772885 LIC10630 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000614.1 769429 R 267671 CDS YP_000615.1 45656529 2772904 770554..771321 1 NC_005823.1 ABC transporter ATP-binding protein 771321 lin 2772904 lin Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_000615.1 770554 D 267671 CDS YP_000616.1 45656530 2770540 771302..772525 1 NC_005823.1 hypothetical protein 772525 2770540 LIC10632 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000616.1 771302 D 267671 CDS YP_000617.1 45656531 2771878 772522..772833 1 NC_005823.1 benzene 1,2-dioxygenase system ferredoxin component 772833 bedB 2771878 bedB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 benzene 1,2-dioxygenase system ferredoxin component YP_000617.1 772522 D 267671 CDS YP_000618.1 45656532 2770692 772830..774080 1 NC_005823.1 selenocysteine reductase 774080 2770692 LIC10634 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 selenocysteine reductase YP_000618.1 772830 D 267671 CDS YP_000619.1 45656533 2771809 774064..774498 1 NC_005823.1 hypothetical protein 774498 nifU 2771809 nifU Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000619.1 774064 D 267671 CDS YP_000620.1 45656534 2770134 774826..775149 1 NC_005823.1 hypothetical protein 775149 2770134 LIC10636 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000620.1 774826 D 267671 CDS YP_000621.1 45656535 2771521 775627..776418 1 NC_005823.1 ribosomal protein serine acetyltransferase 776418 2771521 LIC10637 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribosomal protein serine acetyltransferase YP_000621.1 775627 D 267671 CDS YP_000622.1 45656536 2770354 complement(776975..777502) 1 NC_005823.1 hypothetical protein 777502 2770354 LIC10638 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000622.1 776975 R 267671 CDS YP_000623.1 45656537 2772429 complement(778736..780658) 1 NC_005823.1 hypothetical protein 780658 2772429 LIC10639 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000623.1 778736 R 267671 CDS YP_000624.1 45656538 2770963 complement(781584..782588) 1 NC_005823.1 hypothetical protein 782588 2770963 LIC10640 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000624.1 781584 R 267671 CDS YP_000625.1 45656539 2770453 782652..783980 1 NC_005823.1 EAL domain; identified by sequence similarity; ORF located using Blastx/Glimmer; diguanylate phosphodiesterase 783980 2770453 LIC10641 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 diguanylate phosphodiesterase YP_000625.1 782652 D 267671 CDS YP_000626.1 45656540 2772400 complement(784668..785627) 1 NC_005823.1 hypothetical protein 785627 2772400 LIC10642 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000626.1 784668 R 267671 CDS YP_000627.1 45656541 2772316 complement(785645..786946) 1 NC_005823.1 hypothetical protein 786946 2772316 LIC10643 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000627.1 785645 R 267671 CDS YP_000628.1 45656542 2769853 complement(786949..787473) 1 NC_005823.1 RNA polymerase ECF-type sigma factor 787473 2769853 LIC10644 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA polymerase ECF-type sigma factor YP_000628.1 786949 R 267671 CDS YP_000629.1 45656543 2772402 complement(787762..789036) 1 NC_005823.1 lipoprotein 789036 2772402 LIC10645 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000629.1 787762 R 267671 CDS YP_000630.1 45656544 2769989 complement(790129..791172) 1 NC_005823.1 tRNA-dihydrouridine synthase A 791172 2769989 LIC10646 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tRNA-dihydrouridine synthase A YP_000630.1 790129 R 267671 CDS YP_000631.1 45656545 2769481 791334..792350 1 NC_005823.1 hypothetical protein 792350 2769481 LIC10647 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000631.1 791334 D 267671 CDS YP_000632.1 45656546 2769581 792350..794293 1 NC_005823.1 hypothetical protein 794293 2769581 LIC10648 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000632.1 792350 D 267671 CDS YP_000633.1 45656547 2769692 794491..794676 1 NC_005823.1 hypothetical protein 794676 2769692 LIC10649 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000633.1 794491 D 267671 CDS YP_000634.1 45656548 2772799 794894..795097 1 NC_005823.1 hypothetical protein 795097 2772799 LIC10650 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000634.1 794894 D 267671 CDS YP_000635.1 45656549 2769742 795248..796225 1 NC_005823.1 hypothetical protein 796225 2769742 LIC10651 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000635.1 795248 D 267671 CDS YP_000636.1 45656550 2769601 796409..797101 1 NC_005823.1 ubiquinone/menaquinone methyltransferase 797101 2769601 LIC10652 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ubiquinone/menaquinone methyltransferase YP_000636.1 796409 D 267671 CDS YP_000637.1 45656551 2772037 797586..797774 1 NC_005823.1 hypothetical protein 797774 2772037 LIC10653 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000637.1 797586 D 267671 CDS YP_000638.1 45656552 2772636 797781..798167 1 NC_005823.1 hypothetical protein 798167 2772636 LIC10654 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000638.1 797781 D 267671 CDS YP_000639.1 45656553 2771161 798516..798965 1 NC_005823.1 hypothetical protein 798965 2771161 LIC10655 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000639.1 798516 D 267671 CDS YP_000640.1 45656554 2770455 800133..801206 1 NC_005823.1 transposase, ISlin1 801206 2770455 LIC10656 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_000640.1 800133 D 267671 CDS YP_000641.1 45656555 2771882 802139..803803 1 NC_005823.1 sphingomyelinase C precursor; hemolysin 803803 sphH 2771882 sphH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hemolysin YP_000641.1 802139 D 267671 CDS YP_000642.1 45656556 2770588 complement(804145..805668) 1 NC_005823.1 proton antiporter efflux pump 805668 2770588 LIC10658 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 proton antiporter efflux pump YP_000642.1 804145 R 267671 CDS YP_000643.1 45656557 2770590 complement(805680..806228) 1 NC_005823.1 hypothetical protein 806228 2770590 LIC10659 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000643.1 805680 R 267671 CDS YP_000644.1 45656558 2771901 complement(806241..806981) 1 NC_005823.1 hypothetical protein 806981 2771901 LIC10660 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000644.1 806241 R 267671 CDS YP_000645.1 45656559 2770764 complement(807474..807941) 1 NC_005823.1 hypothetical protein 807941 2770764 LIC10661 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000645.1 807474 R 267671 CDS YP_000646.1 45656560 2771681 complement(808205..808753) 1 NC_005823.1 hypothetical protein 808753 2771681 LIC10662 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000646.1 808205 R 267671 CDS YP_000647.1 45656561 2772161 complement(808775..809254) 1 NC_005823.1 hypothetical protein 809254 2772161 LIC10663 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000647.1 808775 R 267671 CDS YP_000648.1 45656562 2771751 complement(809534..810022) 1 NC_005823.1 hypothetical protein 810022 2771751 LIC10664 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000648.1 809534 R 267671 CDS YP_000649.1 45656563 2770226 complement(810114..810506) 1 NC_005823.1 hypothetical protein 810506 2770226 LIC10665 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000649.1 810114 R 267671 CDS YP_000650.1 45656564 2771689 complement(810487..810867) 1 NC_005823.1 ArsR family transcriptional regulator 810867 2771689 LIC10666 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ArsR family transcriptional regulator YP_000650.1 810487 R 267671 CDS YP_000651.1 45656565 2770946 812419..812886 1 NC_005823.1 thioesterase 812886 2770946 LIC10667 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thioesterase YP_000651.1 812419 D 267671 CDS YP_000652.1 45656566 2772280 813011..813916 1 NC_005823.1 restriction system; Mrr 813916 mrr 2772280 mrr Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Mrr YP_000652.1 813011 D 267671 CDS YP_000653.1 45656567 2772417 813922..814209 1 NC_005823.1 hypothetical protein 814209 2772417 LIC10669 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000653.1 813922 D 267671 CDS YP_000654.1 45656568 2770786 complement(814887..815462) 1 NC_005823.1 hypothetical protein 815462 2770786 LIC10670 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000654.1 814887 R 267671 CDS YP_000655.1 45656569 2772423 816379..817143 1 NC_005823.1 ABC transporter ATP-binding protein 817143 mlr 2772423 mlr Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_000655.1 816379 D 267671 CDS YP_000656.1 45656570 2772243 complement(817144..817833) 1 NC_005823.1 hypothetical protein 817833 2772243 LIC10672 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000656.1 817144 R 267671 CDS YP_000657.1 45656571 2769919 complement(817830..818966) 1 NC_005823.1 hypothetical protein 818966 2769919 LIC10673 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000657.1 817830 R 267671 CDS YP_000658.1 45656572 2772877 complement(819364..819795) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 819795 2772877 LIC10674 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000658.1 819364 R 267671 CDS YP_000659.1 45656573 2769818 820165..820887 1 NC_005823.1 ABC transporter ATP-binding protein 820887 sp 2769818 sp Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_000659.1 820165 D 267671 CDS YP_000660.1 45656574 2772887 820859..821530 1 NC_005823.1 heme exporter protein B 821530 2772887 LIC10676 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heme exporter protein B YP_000660.1 820859 D 267671 CDS YP_000661.1 45656575 2769622 821586..822278 1 NC_005823.1 heme exporter protein C 822278 2769622 LIC10677 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heme exporter protein C YP_000661.1 821586 D 267671 CDS YP_000662.1 45656576 2771623 822285..823418 1 NC_005823.1 response regulator 823418 2771623 LIC10678 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_000662.1 822285 D 267671 CDS YP_000663.1 45656577 2772925 823415..824272 1 NC_005823.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 824272 hemH 2772925 hemH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_000663.1 823415 D 267671 CDS YP_000664.1 45656578 2771081 824248..824496 1 NC_005823.1 hypothetical protein 824496 2771081 LIC10680 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000664.1 824248 D 267671 CDS YP_000665.1 45656579 2770829 824493..825152 1 NC_005823.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 825152 purL 2770829 purL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoribosylformylglycinamidine synthase I YP_000665.1 824493 D 267671 CDS YP_000666.1 45656580 2770694 826217..827305 1 NC_005823.1 methylamine utilization protein/cytochrome c peroxidase 827305 mauG 2770694 mauG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methylamine utilization protein/cytochrome c peroxidase YP_000666.1 826217 D 267671 CDS YP_000667.1 45656581 2772386 827338..827655 1 NC_005823.1 methylamine utilization protein 827655 mauL 2772386 mauL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methylamine utilization protein YP_000667.1 827338 D 267671 CDS YP_000668.1 45656582 2771002 827655..828014 1 NC_005823.1 cytochrome c 828014 2771002 LIC10684 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytochrome c YP_000668.1 827655 D 267671 CDS YP_000669.1 45656583 2770652 828048..829760 1 NC_005823.1 methyl-accepting chemotaxis transducer transmembrane protein 829760 2770652 LIC10685 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methyl-accepting chemotaxis transducer transmembrane protein YP_000669.1 828048 D 267671 CDS YP_000670.1 45656584 2772427 complement(830602..831873) 1 NC_005823.1 lipoprotein 831873 2772427 LIC10686 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000670.1 830602 R 267671 CDS YP_000671.1 45656585 2772744 832500..833078 1 NC_005823.1 hypothetical protein 833078 2772744 LIC10687 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000671.1 832500 D 267671 CDS YP_000672.1 45656586 2770394 833472..833894 1 NC_005823.1 hypothetical protein 833894 2770394 LIC10688 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000672.1 833472 D 267671 CDS YP_000673.1 45656587 2770316 834084..834800 1 NC_005823.1 phosphate transport system protein 834800 phoU 2770316 phoU Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphate transport system protein YP_000673.1 834084 D 267671 CDS YP_000674.1 45656588 2771911 834942..837164 1 NC_005823.1 hypothetical protein 837164 2771911 LIC10690 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000674.1 834942 D 267671 CDS YP_000675.1 45656589 2770636 837891..838385 1 NC_005823.1 hypothetical protein 838385 2770636 LIC10691 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000675.1 837891 D 267671 CDS YP_000676.1 45656590 2771427 complement(839330..840223) 1 NC_005823.1 hypothetical protein 840223 2771427 LIC10692 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000676.1 839330 R 267671 CDS YP_000677.1 45656591 2770282 complement(840974..841258) 1 NC_005823.1 hypothetical protein 841258 2770282 LIC10693 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000677.1 840974 R 267671 CDS YP_000678.1 45656592 2770551 841248..841433 1 NC_005823.1 hypothetical protein 841433 2770551 LIC10694 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000678.1 841248 D 267671 CDS YP_000679.1 45656593 2772182 complement(841805..843724) 1 NC_005823.1 hypothetical protein 843724 2772182 LIC10695 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000679.1 841805 R 267671 CDS YP_000680.1 45656594 2770507 complement(844221..845051) 1 NC_005823.1 hypothetical protein 845051 2770507 LIC10696 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000680.1 844221 R 267671 CDS YP_000681.1 45656595 2771080 complement(845862..846212) 1 NC_005823.1 hypothetical protein 846212 2771080 LIC10697 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000681.1 845862 R 267671 CDS YP_000682.1 45656596 2769638 complement(846347..847021) 1 NC_005823.1 hypothetical protein 847021 2769638 LIC10698 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000682.1 846347 R 267671 CDS YP_000683.1 45656597 2769522 complement(847018..847725) 1 NC_005823.1 hypothetical protein 847725 2769522 LIC10699 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000683.1 847018 R 267671 CDS YP_000684.1 45656598 2769603 847876..848655 1 NC_005823.1 3-oxoacyl-[ACP] reductase oxidoreductase 848655 2769603 LIC10700 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-oxoacyl-[ACP] reductase oxidoreductase YP_000684.1 847876 D 267671 CDS YP_000685.1 45656599 2769555 849438..849635 1 NC_005823.1 hypothetical protein 849635 2769555 LIC10701 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000685.1 849438 D 267671 CDS YP_000686.1 45656600 2771296 850026..850352 1 NC_005823.1 hypothetical protein 850352 2771296 LIC10702 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000686.1 850026 D 267671 CDS YP_000687.1 45656601 2771358 850343..851068 1 NC_005823.1 hypothetical protein 851068 2771358 LIC10703 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000687.1 850343 D 267671 CDS YP_000688.1 45656602 2771550 851080..851748 1 NC_005823.1 lipoprotein 851748 2771550 LIC10704 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000688.1 851080 D 267671 CDS YP_000689.1 45656603 2771438 851803..852345 1 NC_005823.1 hypothetical protein 852345 2771438 LIC10705 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000689.1 851803 D 267671 CDS YP_000690.1 45656604 2769968 852379..852915 1 NC_005823.1 hypothetical protein 852915 2769968 LIC10706 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000690.1 852379 D 267671 CDS YP_000691.1 45656605 2770666 852933..854357 1 NC_005823.1 hypothetical protein 854357 2770666 LIC10707 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000691.1 852933 D 267671 CDS YP_000692.1 45656606 2770562 854348..855073 1 NC_005823.1 hypothetical protein 855073 2770562 LIC10708 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000692.1 854348 D 267671 CDS YP_000693.1 45656607 2770137 855055..855705 1 NC_005823.1 hypothetical protein 855705 2770137 LIC10709 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000693.1 855055 D 267671 CDS YP_000694.1 45656608 2772771 857174..857536 1 NC_005823.1 hypothetical protein 857536 2772771 LIC10710 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000694.1 857174 D 267671 CDS YP_000695.1 45656609 2770202 complement(858185..859399) 1 NC_005823.1 hypothetical protein 859399 2770202 LIC10711 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000695.1 858185 R 267671 CDS YP_000696.1 45656610 2770876 complement(859396..860907) 1 NC_005823.1 hypothetical protein 860907 2770876 LIC10712 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000696.1 859396 R 267671 CDS YP_000697.1 45656611 2770479 complement(860939..862261) 1 NC_005823.1 lipoprotein 862261 2770479 LIC10713 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000697.1 860939 R 267671 CDS YP_000698.1 45656612 2772211 complement(862692..865169) 1 NC_005823.1 outer membrane receptor protein 865169 smc 2772211 smc Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 outer membrane receptor protein YP_000698.1 862692 R 267671 CDS YP_000699.1 45656613 2769745 866582..868984 1 NC_005823.1 thermolysin 868984 2769745 LIC10715 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thermolysin YP_000699.1 866582 D 267671 CDS YP_000700.1 45656614 2771942 complement(870259..870606) 1 NC_005823.1 hypothetical protein 870606 2771942 LIC10716 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000700.1 870259 R 267671 CDS YP_000701.1 45656615 2771072 complement(870588..872171) 1 NC_005823.1 carbon-nitrogen hydrolase 872171 2771072 LIC10717 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 carbon-nitrogen hydrolase YP_000701.1 870588 R 267671 CDS YP_000702.1 45656616 2769747 complement(872171..873616) 1 NC_005823.1 hypothetical protein 873616 2769747 LIC10718 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000702.1 872171 R 267671 CDS YP_000703.1 45656617 2769666 complement(873606..875744) 1 NC_005823.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 875744 ppk 2769666 ppk Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 polyphosphate kinase YP_000703.1 873606 R 267671 CDS YP_000704.1 45656618 2769636 875998..876240 1 NC_005823.1 hypothetical protein 876240 2769636 LIC10720 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000704.1 875998 D 267671 CDS YP_000705.1 45656619 2769643 complement(876991..878184) 1 NC_005823.1 hypothetical protein 878184 2769643 LIC10721 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000705.1 876991 R 267671 CDS YP_000706.1 45656620 2769493 complement(879309..880025) 1 NC_005823.1 glycerol uptake facilitator protein 880025 glpF 2769493 glpF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycerol uptake facilitator protein YP_000706.1 879309 R 267671 CDS YP_000707.1 45656621 2769545 880603..882522 1 NC_005823.1 filament cap protein; involved in flagellin assembly; flagellar hook-associated protein FliD 882522 fliD 2769545 fliD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar hook-associated protein FliD YP_000707.1 880603 D 267671 CDS YP_000708.1 45656622 2769519 882540..883496 1 NC_005823.1 hypothetical protein 883496 2769519 LIC10724 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000708.1 882540 D 267671 CDS YP_000709.1 45656623 2769494 883520..883807 1 NC_005823.1 hypothetical protein 883807 2769494 LIC10725 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000709.1 883520 D 267671 CDS YP_000710.1 45656624 2769564 complement(887819..888775) 1 NC_005823.1 riboflavin biosynthesis protein 888775 ribF 2769564 ribF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 riboflavin biosynthesis protein YP_000710.1 887819 R 267671 CDS YP_000711.1 45656625 2769642 888807..889442 1 NC_005823.1 hypothetical protein 889442 2769642 LIC10729 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000711.1 888807 D 267671 CDS YP_000712.1 45656626 2769598 complement(890170..890649) 1 NC_005823.1 lipoprotein 890649 2769598 LIC10730 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000712.1 890170 R 267671 CDS YP_000713.1 45656627 2769697 890787..892046 1 NC_005823.1 lipoprotein 892046 2769697 LIC10731 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000713.1 890787 D 267671 CDS YP_000714.1 45656628 2770000 893083..893562 1 NC_005823.1 bacterioferritin comigratory protein 893562 2770000 LIC10732 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 bacterioferritin comigratory protein YP_000714.1 893083 D 267671 CDS YP_000715.1 45656629 2771497 893559..895046 1 NC_005823.1 cytosol aminopeptidase protein 895046 pepA 2771497 pepA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytosol aminopeptidase protein YP_000715.1 893559 D 267671 CDS YP_000716.1 45656630 2772519 896198..896992 1 NC_005823.1 lipoprotein 896992 2772519 LIC10734 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000716.1 896198 D 267671 CDS YP_000717.1 45656631 2771810 complement(897691..898203) 1 NC_005823.1 hypothetical protein 898203 2771810 LIC10735 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000717.1 897691 R 267671 CDS YP_000718.1 45656632 2770001 complement(898187..898654) 1 NC_005823.1 hypothetical protein 898654 2770001 LIC10736 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000718.1 898187 R 267671 CDS YP_000719.1 45656633 2771172 898773..899576 1 NC_005823.1 3-demethylubiquinone-9 3-methyltransferase 899576 2771172 LIC10737 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-demethylubiquinone-9 3-methyltransferase YP_000719.1 898773 D 267671 CDS YP_000720.1 45656634 2772432 899573..901195 1 NC_005823.1 ATP-dependent RNA helicase 901195 rhlE 2772432 rhlE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent RNA helicase YP_000720.1 899573 D 267671 CDS YP_000721.1 45656635 2772632 901162..902253 1 NC_005823.1 N-acetylmuramoyl-L-alanine amidase 902253 amiA 2772632 amiA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 N-acetylmuramoyl-L-alanine amidase YP_000721.1 901162 D 267671 CDS YP_000722.1 45656636 2770278 902228..903019 1 NC_005823.1 hypothetical protein 903019 2770278 LIC10740 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000722.1 902228 D 267671 CDS YP_000723.1 45656637 2770894 903042..904640 1 NC_005823.1 hypothetical protein 904640 2770894 LIC10741 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000723.1 903042 D 267671 CDS YP_000724.1 45656638 2772049 complement(906892..907251) 1 NC_005823.1 transposase, ISlin1 907251 2772049 LIC10742 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_000724.1 906892 R 267671 CDS YP_000725.1 45656639 2770020 complement(907257..908003) 1 NC_005823.1 transposase, ISlin1 908003 2770020 LIC10743 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_000725.1 907257 R 267671 CDS YP_000726.1 45656640 2772156 complement(908317..908541) 1 NC_005823.1 hypothetical protein 908541 2772156 LIC10744 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000726.1 908317 R 267671 CDS YP_000727.1 45656641 2770872 909064..909252 1 NC_005823.1 preprotein translocase subunit; forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 909252 secE 2770872 secE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 preprotein translocase subunit SecE YP_000727.1 909064 D 267671 CDS YP_000728.1 45656642 2772247 909280..909825 1 NC_005823.1 transcription antitermination protein 909825 nusG 2772247 nusG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transcription antitermination protein YP_000728.1 909280 D 267671 CDS YP_000729.1 45656643 2772794 909852..910280 1 NC_005823.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 910280 rplK 2772794 rplK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L11 YP_000729.1 909852 D 267671 CDS YP_000730.1 45656644 2772051 910287..910979 1 NC_005823.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 910979 rplA 2772051 rplA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L1 YP_000730.1 910287 D 267671 CDS YP_000731.1 45656645 2770029 911007..911540 1 NC_005823.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 911540 rplJ 2770029 rplJ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L10 YP_000731.1 911007 D 267671 CDS YP_000732.1 45656646 2770178 911590..911973 1 NC_005823.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 911973 rplL 2770178 rplL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L7/L12 YP_000732.1 911590 D 267671 CDS YP_000733.1 45656647 2770463 912196..915876 1 NC_005823.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 915876 rpoB 2770463 rpoB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA-directed RNA polymerase subunit beta YP_000733.1 912196 D 267671 CDS YP_000734.1 45656648 2770415 915880..920094 1 NC_005823.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 920094 rpoC 2770415 rpoC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA-directed RNA polymerase subunit beta' YP_000734.1 915880 D 267671 CDS YP_000735.1 45656649 2771627 920492..920866 1 NC_005823.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 920866 rpsL 2771627 rpsL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S12 YP_000735.1 920492 D 267671 CDS YP_000736.1 45656650 2770061 920885..921358 1 NC_005823.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 921358 rpsG 2770061 rpsG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S7 YP_000736.1 920885 D 267671 CDS YP_000737.1 45656651 2770530 complement(921542..921763) 1 NC_005823.1 hypothetical protein 921763 2770530 LIC10757 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000737.1 921542 R 267671 CDS YP_000738.1 45656652 2771187 complement(922306..922518) 1 NC_005823.1 hypothetical protein 922518 2771187 LIC10758 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000738.1 922306 R 267671 CDS YP_000739.1 45656653 2772560 complement(923278..924201) 1 NC_005823.1 thiamine-monophosphate kinase protein 924201 thiL 2772560 thiL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thiamine-monophosphate kinase protein YP_000739.1 923278 R 267671 CDS YP_000740.1 45656654 2772008 924243..924872 1 NC_005823.1 hypothetical protein 924872 2772008 LIC10760 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000740.1 924243 D 267671 CDS YP_000741.1 45656655 2769864 925859..926308 1 NC_005823.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 926308 rplM 2769864 rplM Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L13 YP_000741.1 925859 D 267671 CDS YP_000742.1 45656656 2772449 926298..926717 1 NC_005823.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 926717 rpsI 2772449 rpsI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S9 YP_000742.1 926298 D 267671 CDS YP_000743.1 45656657 2772349 926801..929734 1 NC_005823.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 929734 alaS 2772349 alaS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alanyl-tRNA synthetase YP_000743.1 926801 D 267671 CDS YP_000744.1 45656658 2770664 929731..930222 1 NC_005823.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 930222 2770664 LIC10764 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 nucleotide-binding protein YP_000744.1 929731 D 267671 CDS YP_000745.1 45656659 2772634 930462..930902 1 NC_005823.1 hypothetical protein 930902 2772634 LIC10765 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000745.1 930462 D 267671 CDS YP_000746.1 45656660 2771807 complement(931865..932299) 1 NC_005823.1 hypothetical protein 932299 2771807 LIC10766 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000746.1 931865 R 267671 CDS YP_000747.1 45656661 2770917 complement(932296..933078) 1 NC_005823.1 hypothetical protein 933078 2770917 LIC10767 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000747.1 932296 R 267671 CDS YP_000748.1 45656662 2770414 933107..934735 1 NC_005823.1 metalloprotease 934735 2770414 LIC10768 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 metalloprotease YP_000748.1 933107 D 267671 CDS YP_000749.1 45656663 2771595 934737..936410 1 NC_005823.1 processing metalloprotease 936410 2771595 LIC10769 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 processing metalloprotease YP_000749.1 934737 D 267671 CDS YP_000750.1 45656664 2770560 936410..937237 1 NC_005823.1 hypothetical protein 937237 2770560 LIC10770 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000750.1 936410 D 267671 CDS YP_000751.1 45656665 2772045 937234..937911 1 NC_005823.1 hypothetical protein 937911 2772045 LIC10771 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000751.1 937234 D 267671 CDS YP_000752.1 45656666 2772491 938092..938916 1 NC_005823.1 hypothetical protein 938916 2772491 LIC10772 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000752.1 938092 D 267671 CDS YP_000753.1 45656667 2770573 938916..940325 1 NC_005823.1 hypothetical protein 940325 2770573 LIC10773 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000753.1 938916 D 267671 CDS YP_000754.1 45656668 2772664 complement(940698..941804) 1 NC_005823.1 lipoprotein 941804 2772664 LIC10774 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000754.1 940698 R 267671 CDS YP_000755.1 45656669 2770399 943264..944442 1 NC_005823.1 hypothetical protein 944442 2770399 LIC10775 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000755.1 943264 D 267671 CDS YP_000756.1 45656670 2771906 944446..945276 1 NC_005823.1 hypothetical protein 945276 2771906 LIC10776 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000756.1 944446 D 267671 CDS YP_000757.1 45656671 2772357 946524..946721 1 NC_005823.1 hypothetical protein 946721 2772357 LIC10777 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000757.1 946524 D 267671 CDS YP_000758.1 45656672 2772466 complement(946836..948731) 1 NC_005823.1 hypothetical protein 948731 2772466 LIC10778 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000758.1 946836 R 267671 CDS YP_000759.1 45656673 2772631 complement(948917..949171) 1 NC_005823.1 hypothetical protein 949171 2772631 LIC10779 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000759.1 948917 R 267671 CDS YP_000760.1 45656674 2772339 complement(949354..949638) 1 NC_005823.1 transposase 949638 2772339 LIC10780 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase YP_000760.1 949354 R 267671 CDS YP_000761.1 45656675 2772817 complement(949924..950229) 1 NC_005823.1 transposase 950229 2772817 LIC10781 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase YP_000761.1 949924 R 267671 CDS YP_000762.1 45656676 2770808 950943..951356 1 NC_005823.1 hypothetical protein 951356 2770808 LIC10782 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000762.1 950943 D 267671 CDS YP_000763.1 45656677 2770699 complement(952496..952834) 1 NC_005823.1 transposase, IS1501 952834 2770699 LIC10784 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, IS1501 YP_000763.1 952496 R 267671 CDS YP_000764.1 45656678 2771189 complement(952875..953138) 1 NC_005823.1 transposase, IS1501 953138 2771189 LIC10785 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, IS1501 YP_000764.1 952875 R 267671 CDS YP_000765.1 45656679 2770405 954186..954380 1 NC_005823.1 hypothetical protein 954380 2770405 LIC10786 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000765.1 954186 D 267671 CDS YP_000766.1 45656680 2770268 954316..955035 1 NC_005823.1 flagellar filament sheath protein 955035 flaA-2 2770268 flaA-2 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar filament sheath protein YP_000766.1 954316 D 267671 CDS YP_000767.1 45656681 2772865 955059..956006 1 NC_005823.1 flagellar filament sheath protein 956006 flaA-1 2772865 flaA-1 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar filament sheath protein YP_000767.1 955059 D 267671 CDS YP_000768.1 45656682 2772333 956203..958983 1 NC_005823.1 contains N-terminal domain of unknown function fused to transcription elongation factor; GreA is necessary for efficient RNA polymerization through arresting sites; cleaves the nascent transcript and allows resumption of transcription elongation; transcript cleavage factor/unknown domain fusion protein 958983 greA 2772333 greA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transcript cleavage factor/unknown domain fusion protein YP_000768.1 956203 D 267671 CDS YP_000769.1 45656683 2771044 complement(959135..959386) 1 NC_005823.1 hypothetical protein 959386 2771044 LIC10790 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000769.1 959135 R 267671 CDS YP_000770.1 45656684 2772202 961450..962082 1 NC_005823.1 cyclic nucleotide binding protein 962082 2772202 LIC10791 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cyclic nucleotide binding protein YP_000770.1 961450 D 267671 CDS YP_000771.1 45656685 2770302 962079..963251 1 NC_005823.1 hypothetical protein 963251 2770302 LIC10792 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000771.1 962079 D 267671 CDS YP_000772.1 45656686 2772677 963262..964632 1 NC_005823.1 surface antigen 964632 orfC 2772677 orfC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 surface antigen YP_000772.1 963262 D 267671 CDS YP_000773.1 45656687 2772938 966137..966400 1 NC_005823.1 hypothetical protein 966400 2772938 LIC10796 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000773.1 966137 D 267671 CDS YP_000774.1 45656688 2769718 966402..966626 1 NC_005823.1 lipoprotein 966626 2769718 LIC10797 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000774.1 966402 D 267671 CDS YP_000775.1 45656689 2769810 966692..967123 1 NC_005823.1 hypothetical protein 967123 2769810 LIC10798 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000775.1 966692 D 267671 CDS YP_000776.1 45656690 2772935 complement(967220..967966) 1 NC_005823.1 enoyl-CoA hydratase 967966 2772935 LIC10799 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 enoyl-CoA hydratase YP_000776.1 967220 R 267671 CDS YP_000777.1 45656691 2772939 complement(968307..969104) 1 NC_005823.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 969104 thiM 2772939 thiM Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hydroxyethylthiazole kinase YP_000777.1 968307 R 267671 CDS YP_000778.1 45656692 2769802 970275..971450 1 NC_005823.1 acyl-CoA dehydrogenase 971450 2769802 LIC10801 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyl-CoA dehydrogenase YP_000778.1 970275 D 267671 CDS YP_000779.1 45656693 2772897 971471..972511 1 NC_005823.1 hypothetical protein 972511 2772897 LIC10802 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000779.1 971471 D 267671 CDS YP_000780.1 45656694 2772907 972501..972896 1 NC_005823.1 hypothetical protein 972896 2772907 LIC10803 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000780.1 972501 D 267671 CDS YP_000781.1 45656695 2772882 972901..973635 1 NC_005823.1 hypothetical protein 973635 2772882 LIC10804 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000781.1 972901 D 267671 CDS YP_000782.1 45656696 2772886 974378..974845 1 NC_005823.1 hypothetical protein 974845 2772886 LIC10805 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000782.1 974378 D 267671 CDS YP_000783.1 45656697 2772889 975553..977691 1 NC_005823.1 histidine kinase sensor protein 977691 2772889 LIC10806 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_000783.1 975553 D 267671 CDS YP_000784.1 45656698 2770864 complement(977875..978369) 1 NC_005823.1 glutathione S-transferase 978369 gst 2770864 gst Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutathione S-transferase YP_000784.1 977875 R 267671 CDS YP_000785.1 45656699 2771597 complement(979168..979743) 1 NC_005823.1 hypothetical protein 979743 2771597 LIC10808 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000785.1 979168 R 267671 CDS YP_000786.1 45656700 2769715 980016..981062 1 NC_005823.1 zinc binding dehydrogenase 981062 adh 2769715 adh Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 zinc binding dehydrogenase YP_000786.1 980016 D 267671 CDS YP_000787.1 45656701 2769988 complement(981378..982091) 1 NC_005823.1 hypothetical protein 982091 2769988 LIC10810 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000787.1 981378 R 267671 CDS YP_000788.1 45656702 2772436 complement(982058..982456) 1 NC_005823.1 hypothetical protein 982456 2772436 LIC10811 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000788.1 982058 R 267671 CDS YP_000789.1 45656703 2772535 complement(982456..983055) 1 NC_005823.1 cytochrome c-type biogenesis precursor 983055 ccmH 2772535 ccmH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytochrome c-type biogenesis precursor YP_000789.1 982456 R 267671 CDS YP_000790.1 45656704 2771972 complement(983052..985241) 1 NC_005823.1 cytochrome C biogenesis protein 985241 ccmF 2771972 ccmF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytochrome C biogenesis protein YP_000790.1 983052 R 267671 CDS YP_000791.1 45656705 2772120 complement(985264..985659) 1 NC_005823.1 cytochrome c-type biogenesis protein 985659 ccmE 2772120 ccmE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytochrome c-type biogenesis protein YP_000791.1 985264 R 267671 CDS YP_000792.1 45656706 2771410 complement(985885..986661) 1 NC_005823.1 hypothetical protein 986661 2771410 LIC10815 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000792.1 985885 R 267671 CDS YP_000793.1 45656707 2772513 987872..988156 1 NC_005823.1 hypothetical protein 988156 2772513 LIC10816 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000793.1 987872 D 267671 CDS YP_000794.1 45656708 2772868 988881..989531 1 NC_005823.1 hypothetical protein 989531 2772868 LIC10817 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000794.1 988881 D 267671 CDS YP_000795.1 45656709 2770075 complement(989991..990233) 1 NC_005823.1 hypothetical protein 990233 2770075 LIC10818 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000795.1 989991 R 267671 CDS YP_000796.1 45656710 2772586 complement(991122..991310) 1 NC_005823.1 hypothetical protein 991310 2772586 LIC10819 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000796.1 991122 R 267671 CDS YP_000797.1 45656711 2772133 991747..991935 1 NC_005823.1 hypothetical protein 991935 2772133 LIC10820 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000797.1 991747 D 267671 CDS YP_000798.1 45656712 2769961 complement(991916..992989) 1 NC_005823.1 lipoprotein 992989 2769961 LIC10821 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000798.1 991916 R 267671 CDS YP_000799.1 45656713 2772646 complement(993739..994362) 1 NC_005823.1 hypothetical protein 994362 2772646 LIC10822 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000799.1 993739 R 267671 CDS YP_000800.1 45656714 2770176 complement(994371..996125) 1 NC_005823.1 hypothetical protein 996125 2770176 LIC10823 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000800.1 994371 R 267671 CDS YP_000801.1 45656715 2771047 complement(996107..996991) 1 NC_005823.1 hypothetical protein 996991 2771047 LIC10824 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000801.1 996107 R 267671 CDS YP_000802.1 45656716 2769975 997162..1004301 1 NC_005823.1 rhs; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 1004301 2769975 LIC10825 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000802.1 997162 D 267671 CDS YP_000803.1 45656717 2769880 1004318..1004920 1 NC_005823.1 lipoprotein 1004920 2769880 LIC10826 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000803.1 1004318 D 267671 CDS YP_000804.1 45656718 2772433 1005052..1005903 1 NC_005823.1 hypothetical protein 1005903 2772433 LIC10827 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000804.1 1005052 D 267671 CDS YP_000805.1 45656719 2770538 complement(1005970..1007106) 1 NC_005823.1 internal repeat sequences detected; contains Leucine rich repeat as detected by pfam-hmmr; hypothetical protein 1007106 2770538 LIC10828 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000805.1 1005970 R 267671 CDS YP_000806.1 45656720 2769900 complement(1007309..1008517) 1 NC_005823.1 internal repeat sequences detected; contains Leucine rich repeat as detected by pfam-hmmr; hypothetical protein 1008517 2769900 LIC10829 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000806.1 1007309 R 267671 CDS YP_000807.1 45656721 2772171 complement(1008772..1010337) 1 NC_005823.1 contains leucine-rich repeats; identified by sequence similarity; ORF located using Blastx/Glimmer; lipoprotein 1010337 2772171 LIC10830 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000807.1 1008772 R 267671 CDS YP_000808.1 45656722 2770683 complement(1010539..1011672) 1 NC_005823.1 internal repeat sequences detected; contains Leucine rich repeat as detected by pfam-hmmr; hypothetical protein 1011672 2770683 LIC10831 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000808.1 1010539 R 267671 CDS YP_000809.1 45656723 2772050 1011880..1012251 1 NC_005823.1 hypothetical protein 1012251 2772050 LIC10832 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000809.1 1011880 D 267671 CDS YP_000810.1 45656724 2771063 1012299..1012811 1 NC_005823.1 hypothetical protein 1012811 2771063 LIC10833 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000810.1 1012299 D 267671 CDS YP_000811.1 45656725 2770662 1013489..1014082 1 NC_005823.1 hypothetical protein 1014082 2770662 LIC10834 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000811.1 1013489 D 267671 CDS YP_000812.1 45656726 2771035 1014154..1015041 1 NC_005823.1 hypothetical protein 1015041 2771035 LIC10835 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000812.1 1014154 D 267671 CDS YP_000813.1 45656727 2769871 1015159..1015905 1 NC_005823.1 ribosomal-protein-serine-acetyltransferase 1015905 rimL 2769871 rimL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribosomal-protein-serine-acetyltransferase YP_000813.1 1015159 D 267671 CDS YP_000814.1 45656728 2770771 1016075..1016977 1 NC_005823.1 cell division inhibitor 1016977 sulA 2770771 sulA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cell division inhibitor YP_000814.1 1016075 D 267671 CDS YP_000815.1 45656729 2771950 1018214..1018639 1 NC_005823.1 glyoxalase 1018639 gloA 2771950 gloA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glyoxalase YP_000815.1 1018214 D 267671 CDS YP_000816.1 45656730 2770393 1018975..1019382 1 NC_005823.1 hypothetical protein 1019382 2770393 LIC10839 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000816.1 1018975 D 267671 CDS YP_000817.1 45656731 2770315 1019932..1020165 1 NC_005823.1 hypothetical protein 1020165 2770315 LIC10840 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000817.1 1019932 D 267671 CDS YP_000818.1 45656732 2770119 complement(1020492..1021406) 1 NC_005823.1 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 1021406 rfe 2770119 rfe Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase YP_000818.1 1020492 R 267671 CDS YP_000819.1 45656733 2770130 1021594..1022517 1 NC_005823.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1022517 dapA 2770130 dapA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dihydrodipicolinate synthase YP_000819.1 1021594 D 267671 CDS YP_000820.1 45656734 2772358 1022521..1023333 1 NC_005823.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1023333 dapB 2772358 dapB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dihydrodipicolinate reductase YP_000820.1 1022521 D 267671 CDS YP_000821.1 45656735 2771818 1023346..1024167 1 NC_005823.1 hypothetical protein 1024167 2771818 LIC10844 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000821.1 1023346 D 267671 CDS YP_000822.1 45656736 2769865 1024170..1025225 1 NC_005823.1 hypothetical protein 1025225 2769865 LIC10845 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000822.1 1024170 D 267671 CDS YP_000823.1 45656737 2770485 1025222..1025602 1 NC_005823.1 Acps; ACP synthase 1025602 acps 2770485 acps Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ACP synthase YP_000823.1 1025222 D 267671 CDS YP_000824.1 45656738 2772505 1025606..1025827 1 NC_005823.1 hypothetical protein 1025827 2772505 LIC10847 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000824.1 1025606 D 267671 CDS YP_000825.1 45656739 2772109 1025836..1026213 1 NC_005823.1 hypothetical protein 1026213 2772109 LIC10848 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000825.1 1025836 D 267671 CDS YP_000826.1 45656740 2770184 1026236..1026496 1 NC_005823.1 hypothetical protein 1026496 2770184 LIC10849 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000826.1 1026236 D 267671 CDS YP_000827.1 45656741 2770841 1026500..1027384 1 NC_005823.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1027384 rpsB 2770841 rpsB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S2 YP_000827.1 1026500 D 267671 CDS YP_000828.1 45656742 2770747 1027396..1027995 1 NC_005823.1 EF-Ts; EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1027995 tsf 2770747 tsf Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 elongation factor Ts YP_000828.1 1027396 D 267671 CDS YP_000829.1 45656743 2770216 1027999..1028745 1 NC_005823.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1028745 pyrH 2770216 pyrH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 uridylate kinase YP_000829.1 1027999 D 267671 CDS YP_000830.1 45656744 2771965 1028735..1029289 1 NC_005823.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1029289 frr 2771965 frr Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribosome recycling factor YP_000830.1 1028735 D 267671 CDS YP_000831.1 45656745 2771293 1029291..1030016 1 NC_005823.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 1030016 uppS 2771293 uppS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 undecaprenyl pyrophosphate synthase YP_000831.1 1029291 D 267671 CDS YP_000832.1 45656746 2772692 1030009..1030917 1 NC_005823.1 CDP-diglyceride synthetase 1030917 cds 2772692 cds Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 CDP-diglyceride synthetase YP_000832.1 1030009 D 267671 CDS YP_000833.1 45656747 2770253 1030924..1032093 1 NC_005823.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1032093 dxr 2770253 dxr Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_000833.1 1030924 D 267671 CDS YP_000834.1 45656748 2772715 1032087..1033814 1 NC_005823.1 integral membrane zinc metalloprotease 1033814 2772715 LIC10857 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 integral membrane zinc metalloprotease YP_000834.1 1032087 D 267671 CDS YP_000835.1 45656749 2770123 1033820..1035550 1 NC_005823.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1035550 proS 2770123 proS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 prolyl-tRNA synthetase YP_000835.1 1033820 D 267671 CDS YP_000836.1 45656750 2771514 1035553..1036746 1 NC_005823.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1036746 trpB1 2771514 trpB1 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tryptophan synthase subunit beta YP_000836.1 1035553 D 267671 CDS YP_000837.1 45656751 2772025 1036743..1037537 1 NC_005823.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1037537 trpA 2772025 trpA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tryptophan synthase subunit alpha YP_000837.1 1036743 D 267671 CDS YP_000838.1 45656752 2771018 complement(1037572..1038132) 1 NC_005823.1 hypothetical protein 1038132 2771018 LIC10861 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000838.1 1037572 R 267671 CDS YP_000839.1 45656753 2772115 1038201..1040513 1 NC_005823.1 adenylate/guanylate cyclase 1040513 2772115 LIC10862 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_000839.1 1038201 D 267671 CDS YP_000840.1 45656754 2771811 1040546..1042450 1 NC_005823.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 1042450 dxs 2771811 dxs Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 1-deoxy-D-xylulose-5-phosphate synthase YP_000840.1 1040546 D 267671 CDS YP_000841.1 45656755 2772752 1042484..1042960 1 NC_005823.1 hypothetical protein 1042960 2772752 LIC10864 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000841.1 1042484 D 267671 CDS YP_000842.1 45656756 2772434 1044058..1044879 1 NC_005823.1 hypothetical protein 1044879 2772434 LIC10865 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000842.1 1044058 D 267671 CDS YP_000843.1 45656757 2770765 complement(1045304..1045747) 1 NC_005823.1 hypothetical protein 1045747 2770765 LIC10866 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000843.1 1045304 R 267671 CDS YP_000844.1 45656758 2772100 complement(1045737..1045955) 1 NC_005823.1 hypothetical protein 1045955 2772100 LIC10867 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000844.1 1045737 R 267671 CDS YP_000845.1 45656759 2771156 1046489..1047883 1 NC_005823.1 internal repeat sequences detected; contains Beta-propeller repeat as detected by pfam-hmmr; hypothetical protein 1047883 2771156 LIC10868 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000845.1 1046489 D 267671 CDS YP_000846.1 45656760 2772552 1048107..1048919 1 NC_005823.1 hypothetical protein 1048919 2772552 LIC10869 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000846.1 1048107 D 267671 CDS YP_000847.1 45656761 2771380 complement(1050515..1052425) 1 NC_005823.1 hypothetical protein 1052425 2771380 LIC10870 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000847.1 1050515 R 267671 CDS YP_000848.1 45656762 2771754 complement(1054511..1055119) 1 NC_005823.1 hypothetical protein 1055119 2771754 LIC10871 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000848.1 1054511 R 267671 CDS YP_000849.1 45656763 2771108 complement(1055116..1055328) 1 NC_005823.1 hypothetical protein 1055328 2771108 LIC10872 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000849.1 1055116 R 267671 CDS YP_000850.1 45656764 2772309 1055618..1056124 1 NC_005823.1 hypothetical protein 1056124 2772309 LIC10873 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000850.1 1055618 D 267671 CDS YP_000851.1 45656765 2771088 1056144..1059251 1 NC_005823.1 molybdopterin oxidoreductase 1059251 2771088 LIC10874 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 molybdopterin oxidoreductase YP_000851.1 1056144 D 267671 CDS YP_000852.1 45656766 2772200 1059271..1060644 1 NC_005823.1 molybdopterin oxidoredutase membrane subunit 1060644 2772200 LIC10875 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 molybdopterin oxidoredutase membrane subunit YP_000852.1 1059271 D 267671 CDS YP_000853.1 45656767 2772454 1060644..1061195 1 NC_005823.1 hypothetical protein 1061195 2772454 LIC10876 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000853.1 1060644 D 267671 CDS YP_000854.2 304570487 2770283 1061240..1061791 1 NC_005823.1 hypothetical protein 1061791 2770283 LIC10877 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000854.2 1061240 D 267671 CDS YP_000855.1 45656769 2769743 1061797..1063020 1 NC_005823.1 hypothetical protein 1063020 2769743 LIC10878 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000855.1 1061797 D 267671 CDS YP_000856.1 45656770 2769756 1063032..1063511 1 NC_005823.1 lipoprotein 1063511 2769756 LIC10879 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000856.1 1063032 D 267671 CDS YP_000857.1 45656771 2772089 1063672..1064139 1 NC_005823.1 hypothetical protein 1064139 2772089 LIC10880 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000857.1 1063672 D 267671 CDS YP_000858.1 45656772 2769656 1064898..1066571 1 NC_005823.1 outer membrane protein, TonB dependent 1066571 2769656 LIC10881 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 outer membrane protein, TonB dependent YP_000858.1 1064898 D 267671 CDS YP_000859.1 45656773 2769580 1066668..1067723 1 NC_005823.1 hypothetical protein 1067723 2769580 LIC10882 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000859.1 1066668 D 267671 CDS YP_000860.1 45656774 2769695 1069164..1069778 1 NC_005823.1 hypothetical protein 1069778 2769695 LIC10883 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000860.1 1069164 D 267671 CDS YP_000861.1 45656775 2769511 1070404..1070799 1 NC_005823.1 transposase, ISlin1 1070799 2769511 LIC10884 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_000861.1 1070404 D 267671 CDS YP_000862.1 45656776 2769568 1070768..1071355 1 NC_005823.1 transposase, ISlin1 1071355 2769568 LIC10885 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_000862.1 1070768 D 267671 CDS YP_000863.1 45656777 2769509 1071340..1071720 1 NC_005823.1 transposase, ISlin1 1071720 2769509 LIC10886 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_000863.1 1071340 D 267671 CDS YP_000864.1 45656778 2769492 complement(1072177..1072626) 1 NC_005823.1 transposase, ISlin1 1072626 2769492 LIC10887 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_000864.1 1072177 R 267671 CDS YP_000865.1 45656779 2769476 complement(1072657..1073286) 1 NC_005823.1 transposase, ISlin1 1073286 2769476 LIC10888 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_000865.1 1072657 R 267671 CDS YP_000866.1 45656780 2769538 complement(1073955..1074545) 1 NC_005823.1 TonB 1074545 tonB 2769538 tonB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 TonB YP_000866.1 1073955 R 267671 CDS YP_000867.1 45656781 2769641 complement(1074549..1074959) 1 NC_005823.1 hypothetical protein 1074959 2769641 LIC10890 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000867.1 1074549 R 267671 CDS YP_000868.1 45656782 2769685 complement(1074962..1075399) 1 NC_005823.1 hypothetical protein 1075399 2769685 LIC10891 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000868.1 1074962 R 267671 CDS YP_000869.1 45656783 2769755 complement(1075408..1076220) 1 NC_005823.1 biopolymer transport exbB-like protein 1076220 2769755 LIC10892 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 biopolymer transport exbB-like protein YP_000869.1 1075408 R 267671 CDS YP_000870.1 45656784 2769702 complement(1076584..1077120) 1 NC_005823.1 hypothetical protein 1077120 2769702 LIC10893 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000870.1 1076584 R 267671 CDS YP_000871.1 45656785 2769707 complement(1077790..1077978) 1 NC_005823.1 hypothetical protein 1077978 2769707 LIC10894 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000871.1 1077790 R 267671 CDS YP_000872.1 45656786 2772193 complement(1078404..1078715) 1 NC_005823.1 hypothetical protein 1078715 2772193 LIC10895 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000872.1 1078404 R 267671 CDS YP_000873.1 45656787 2771284 complement(1078721..1081378) 1 NC_005823.1 TonB-dependent outer membrane receptor 1081378 fecA 2771284 fecA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 TonB-dependent outer membrane receptor YP_000873.1 1078721 R 267671 CDS YP_000874.1 45656788 2771621 complement(1081360..1082103) 1 NC_005823.1 hypothetical protein 1082103 2771621 LIC10897 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000874.1 1081360 R 267671 CDS YP_000875.1 45656789 2771538 complement(1082177..1083709) 1 NC_005823.1 outer membrance lipoprotein; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 1083709 lipL48 2771538 lipL48 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000875.1 1082177 R 267671 CDS YP_000876.1 45656790 2772070 complement(1083716..1084030) 1 NC_005823.1 hypothetical protein 1084030 2772070 LIC10899 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000876.1 1083716 R 267671 CDS YP_000877.1 45656791 2772173 1085410..1086813 1 NC_005823.1 adenylate/guanylate cyclase 1086813 2772173 LIC10900 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_000877.1 1085410 D 267671 CDS YP_000878.1 45656792 2772232 1086791..1087210 1 NC_005823.1 adenylate/guanylate cyclase 1087210 2772232 LIC10901 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_000878.1 1086791 D 267671 CDS YP_000879.1 45656793 2772551 1087216..1088334 1 NC_005823.1 hypothetical protein 1088334 2772551 LIC10902 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000879.1 1087216 D 267671 CDS YP_000880.1 45656794 2771691 complement(1088388..1088576) 1 NC_005823.1 hypothetical protein 1088576 2771691 LIC10903 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000880.1 1088388 R 267671 CDS YP_000881.1 45656795 2770372 complement(1089574..1089978) 1 NC_005823.1 hypothetical protein 1089978 2770372 LIC10904 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000881.1 1089574 R 267671 CDS YP_000882.1 45656796 2770334 complement(1090216..1090440) 1 NC_005823.1 hypothetical protein 1090440 2770334 LIC10905 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000882.1 1090216 R 267671 CDS YP_000883.1 45656797 2772595 1090528..1091436 1 NC_005823.1 hypothetical protein 1091436 2772595 LIC10906 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000883.1 1090528 D 267671 CDS YP_000884.1 45656798 2772802 1091629..1091955 1 NC_005823.1 hypothetical protein 1091955 2772802 LIC10907 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000884.1 1091629 D 267671 CDS YP_000885.1 45656799 2770954 1092059..1092268 1 NC_005823.1 hypothetical protein 1092268 2770954 LIC10908 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000885.1 1092059 D 267671 CDS YP_000886.1 45656800 2769956 complement(1092721..1093137) 1 NC_005823.1 hypothetical protein 1093137 2769956 LIC10909 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000886.1 1092721 R 267671 CDS YP_000887.1 45656801 2770505 1096223..1096609 1 NC_005823.1 hypothetical protein 1096609 2770505 LIC10912 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000887.1 1096223 D 267671 CDS YP_000888.1 45656802 2772273 1096630..1097496 1 NC_005823.1 transketolase subunit alpha protein 1097496 tktA 2772273 tktA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transketolase subunit alpha protein YP_000888.1 1096630 D 267671 CDS YP_000889.1 45656803 2770107 complement(1097742..1098002) 1 NC_005823.1 hypothetical protein 1098002 2770107 LIC10914 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000889.1 1097742 R 267671 CDS YP_000890.1 45656804 2771248 1098554..1099540 1 NC_005823.1 hypothetical protein 1099540 2771248 LIC10915 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000890.1 1098554 D 267671 CDS YP_000891.1 45656805 2771881 1099592..1100551 1 NC_005823.1 octaprenyl diphosphate synthase 1100551 ispB 2771881 ispB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 octaprenyl diphosphate synthase YP_000891.1 1099592 D 267671 CDS YP_000892.1 45656806 2771893 complement(1100960..1101148) 1 NC_005823.1 hypothetical protein 1101148 2771893 LIC10917 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000892.1 1100960 R 267671 CDS YP_000893.1 45656807 2771700 1101767..1102270 1 NC_005823.1 hypothetical protein 1102270 2771700 LIC10918 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000893.1 1101767 D 267671 CDS YP_000894.1 45656808 2770789 1102312..1102986 1 NC_005823.1 hypothetical protein 1102986 2770789 LIC10919 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000894.1 1102312 D 267671 CDS YP_000895.1 45656809 2772807 complement(1103428..1104183) 1 NC_005823.1 lipoprotein 1104183 2772807 LIC10920 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000895.1 1103428 R 267671 CDS YP_000896.1 45656810 2770183 complement(1104225..1104452) 1 NC_005823.1 hypothetical protein 1104452 2770183 LIC10921 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000896.1 1104225 R 267671 CDS YP_000897.1 45656811 2769987 1105524..1109021 1 NC_005823.1 histidine kinase sensor protein 1109021 2769987 LIC10922 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_000897.1 1105524 D 267671 CDS YP_000898.1 45656812 2771668 1109018..1109425 1 NC_005823.1 response regulator 1109425 2771668 LIC10923 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_000898.1 1109018 D 267671 CDS YP_000899.1 45656813 2771783 complement(1109497..1109703) 1 NC_005823.1 hypothetical protein 1109703 2771783 LIC10924 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000899.1 1109497 R 267671 CDS YP_000900.1 45656814 2771391 1109692..1110714 1 NC_005823.1 metallo-beta-lactamase 1110714 2771391 LIC10925 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 metallo-beta-lactamase YP_000900.1 1109692 D 267671 CDS YP_000901.1 45656815 2771985 complement(1110807..1110998) 1 NC_005823.1 hypothetical protein 1110998 2771985 LIC10926 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000901.1 1110807 R 267671 CDS YP_000902.1 45656816 2772290 complement(1111593..1113086) 1 NC_005823.1 lipoprotein 1113086 2772290 LIC10927 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000902.1 1111593 R 267671 CDS YP_000903.1 45656817 2769969 complement(1118133..1121231) 1 NC_005823.1 type I restriction enzyme 1121231 2769969 LIC10929 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 type I restriction enzyme YP_000903.1 1118133 R 267671 CDS YP_000904.1 45656818 2770616 complement(1121249..1122400) 1 NC_005823.1 anticodon nuclease 1122400 prrC 2770616 prrC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anticodon nuclease YP_000904.1 1121249 R 267671 CDS YP_000905.1 45656819 2772676 complement(1122397..1123578) 1 NC_005823.1 type I restriction enzyme 1123578 2772676 LIC10931 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 type I restriction enzyme YP_000905.1 1122397 R 267671 CDS YP_000906.1 45656820 2772219 complement(1123575..1125116) 1 NC_005823.1 type I restriction enzyme 1125116 2772219 LIC10932 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 type I restriction enzyme YP_000906.1 1123575 R 267671 CDS YP_000907.1 45656821 2771048 complement(1125582..1125983) 1 NC_005823.1 hypothetical protein 1125983 2771048 LIC10933 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000907.1 1125582 R 267671 CDS YP_000908.1 45656822 2771507 1126319..1126627 1 NC_005823.1 hypothetical protein 1126627 2771507 LIC10934 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000908.1 1126319 D 267671 CDS YP_000909.1 45656823 2770425 complement(1127064..1127687) 1 NC_005823.1 fruiting body developmental protein 1127687 devS 2770425 devS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 fruiting body developmental protein YP_000909.1 1127064 R 267671 CDS YP_000910.1 45656824 2772322 complement(1127708..1128547) 1 NC_005823.1 fruiting body developmental protein 1128547 devR 2772322 devR Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 fruiting body developmental protein YP_000910.1 1127708 R 267671 CDS YP_000911.1 45656825 2772259 complement(1128612..1130498) 1 NC_005823.1 hypothetical protein 1130498 2772259 LIC10937 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000911.1 1128612 R 267671 CDS YP_000912.1 45656826 2770380 complement(1130506..1132758) 1 NC_005823.1 ATP-dependent RNA helicase 1132758 2770380 LIC10938 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent RNA helicase YP_000912.1 1130506 R 267671 CDS YP_000913.1 45656827 2772627 complement(1132755..1133387) 1 NC_005823.1 hypothetical protein 1133387 2772627 LIC10939 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000913.1 1132755 R 267671 CDS YP_000914.1 45656828 2770854 1134138..1134350 1 NC_005823.1 hypothetical protein 1134350 2770854 LIC10940 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000914.1 1134138 D 267671 CDS YP_000915.1 45656829 2772685 complement(1134467..1134751) 1 NC_005823.1 hypothetical protein 1134751 2772685 LIC10941 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000915.1 1134467 R 267671 CDS YP_000916.1 45656830 2771104 complement(1134751..1135605) 1 NC_005823.1 hypothetical protein 1135605 2771104 LIC10942 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000916.1 1134751 R 267671 CDS YP_000917.1 45656831 2769995 complement(1135774..1136403) 1 NC_005823.1 hypothetical protein 1136403 2769995 LIC10943 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000917.1 1135774 R 267671 CDS YP_000918.1 45656832 2771448 complement(1137595..1138482) 1 NC_005823.1 hypothetical protein 1138482 2771448 LIC10944 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000918.1 1137595 R 267671 CDS YP_000919.1 45656833 2770978 1138702..1138956 1 NC_005823.1 hypothetical protein 1138956 2770978 LIC10945 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000919.1 1138702 D 267671 CDS YP_000920.1 45656834 2771576 complement(1139140..1139526) 1 NC_005823.1 hypothetical protein 1139526 2771576 LIC10946 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000920.1 1139140 R 267671 CDS YP_000921.1 45656835 2770180 complement(1139869..1140420) 1 NC_005823.1 hypothetical protein 1140420 2770180 LIC10947 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000921.1 1139869 R 267671 CDS YP_000922.1 45656836 2770957 complement(1141562..1143058) 1 NC_005823.1 ABC transporter ATP-binding protein 1143058 2770957 LIC10948 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_000922.1 1141562 R 267671 CDS YP_000923.1 45656837 2772719 complement(1143623..1144459) 1 NC_005823.1 aldo/keto reductase 1144459 dkgA 2772719 dkgA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aldo/keto reductase YP_000923.1 1143623 R 267671 CDS YP_000924.1 45656838 2770557 complement(1145949..1147658) 1 NC_005823.1 sigma factor regulatory protein 1147658 2770557 LIC10950 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sigma factor regulatory protein YP_000924.1 1145949 R 267671 CDS YP_000925.1 45656839 2772867 complement(1147639..1147851) 1 NC_005823.1 hypothetical protein 1147851 2772867 LIC10951 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000925.1 1147639 R 267671 CDS YP_000926.1 45656840 2769854 1147903..1149108 1 NC_005823.1 contains phosphoesterase domain; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 1149108 2769854 LIC10952 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000926.1 1147903 D 267671 CDS YP_000927.1 45656841 2772863 1149409..1150074 1 NC_005823.1 internal repeat sequences detected; contains MORN repeat as detected by pfam-hmmr; hypothetical protein 1150074 2772863 LIC10953 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000927.1 1149409 D 267671 CDS YP_000928.1 45656842 2772141 1151204..1151587 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 1151587 2772141 LIC10954 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000928.1 1151204 D 267671 CDS YP_000929.1 45656843 2771632 complement(1151785..1153776) 1 NC_005823.1 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase 1153776 gcpE 2771632 gcpE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase YP_000929.1 1151785 R 267671 CDS YP_000930.1 45656844 2772756 1153886..1154125 1 NC_005823.1 hypothetical protein 1154125 2772756 LIC10956 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000930.1 1153886 D 267671 CDS YP_000931.1 45656845 2771642 1154115..1154348 1 NC_005823.1 hypothetical protein 1154348 2771642 LIC10957 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000931.1 1154115 D 267671 CDS YP_000932.1 45656846 2770846 1154563..1155576 1 NC_005823.1 alcohol dehydrogenase 1155576 2770846 LIC10958 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alcohol dehydrogenase YP_000932.1 1154563 D 267671 CDS YP_000933.1 45656847 2772876 complement(1156001..1157407) 1 NC_005823.1 flavin-binding family; identified by sequence similarity; ORF located using Blastx/Glimmer; monooxygenase 1157407 2772876 LIC10959 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 monooxygenase YP_000933.1 1156001 R 267671 CDS YP_000934.1 45656848 2771259 1157894..1158247 1 NC_005823.1 hypothetical protein 1158247 2771259 LIC10960 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000934.1 1157894 D 267671 CDS YP_000935.1 45656849 2772888 complement(1158237..1158482) 1 NC_005823.1 transposase 1158482 2772888 LIC10961 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase YP_000935.1 1158237 R 267671 CDS YP_000936.1 45656850 2772892 1160309..1160776 1 NC_005823.1 hypothetical protein 1160776 2772892 LIC10962 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000936.1 1160309 D 267671 CDS YP_000937.1 45656851 2772948 complement(1161319..1161693) 1 NC_005823.1 hypothetical protein 1161693 2772948 LIC10963 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000937.1 1161319 R 267671 CDS YP_000938.1 45656852 2772912 complement(1161704..1164037) 1 NC_005823.1 TonB-dependent outer membrane hemin receptor 1164037 phuR 2772912 phuR Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 TonB-dependent outer membrane hemin receptor YP_000938.1 1161704 R 267671 CDS YP_000939.1 45656853 2772947 complement(1164084..1164416) 1 NC_005823.1 hypothetical protein 1164416 2772947 LIC10965 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000939.1 1164084 R 267671 CDS YP_000940.1 45656854 2769565 complement(1164893..1165756) 1 NC_005823.1 hypothetical protein 1165756 2769565 LIC10966 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000940.1 1164893 R 267671 CDS YP_000941.1 45656855 2769679 1165804..1166190 1 NC_005823.1 small multidrug resistance protein 1166190 2769679 LIC10967 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 small multidrug resistance protein YP_000941.1 1165804 D 267671 CDS YP_000942.1 45656856 2769700 complement(1166708..1167784) 1 NC_005823.1 internal repeat sequences detected; contains NHL repeat as detected by pfam-hmmr; hypothetical protein 1167784 2769700 LIC10968 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000942.1 1166708 R 267671 CDS YP_000943.1 45656857 2772874 1168252..1169424 1 NC_005823.1 alpha-methylacyl-CoA racemase 1169424 2772874 LIC10969 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alpha-methylacyl-CoA racemase YP_000943.1 1168252 D 267671 CDS YP_000944.1 45656858 2769758 1169606..1170862 1 NC_005823.1 acyl-CoA dehydrogenase 1170862 2769758 LIC10970 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyl-CoA dehydrogenase YP_000944.1 1169606 D 267671 CDS YP_000945.1 45656859 2769706 1170840..1171037 1 NC_005823.1 hypothetical protein 1171037 2769706 LIC10971 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000945.1 1170840 D 267671 CDS YP_000946.1 45656860 2769533 1172279..1173238 1 NC_005823.1 methylamine utilization protein; cytochrome c peroxidase 1173238 2769533 LIC10972 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytochrome c peroxidase YP_000946.1 1172279 D 267671 CDS YP_000947.1 45656861 2769678 complement(1173342..1174304) 1 NC_005823.1 contains porin activity; identified by sequence similarity; ORF located using Blastx/Glimmer; outer membrane protein 1174304 ompL1 2769678 ompL1 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 outer membrane protein YP_000947.1 1173342 R 267671 CDS YP_000948.1 45656862 2772951 complement(1176400..1177611) 1 NC_005823.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 1177611 2772951 LIC10974 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyl-CoA acetyltransferase YP_000948.1 1176400 R 267671 CDS YP_000949.1 45656863 2769567 complement(1178726..1179907) 1 NC_005823.1 AraC family transcriptional regulator 1179907 2769567 LIC10975 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 AraC family transcriptional regulator YP_000949.1 1178726 R 267671 CDS YP_000950.1 45656864 2770717 1182095..1183198 1 NC_005823.1 hypothetical protein 1183198 2770717 LIC10976 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000950.1 1182095 D 267671 CDS YP_000951.1 45656865 2771718 complement(1183182..1184090) 1 NC_005823.1 sodium bile acid symporter family protein 1184090 2771718 LIC10977 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sodium bile acid symporter family protein YP_000951.1 1183182 R 267671 CDS YP_000952.1 45656866 2772638 complement(1184095..1184883) 1 NC_005823.1 syringomycin channel-forming protein 1184883 2772638 LIC10978 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 syringomycin channel-forming protein YP_000952.1 1184095 R 267671 CDS YP_000953.1 45656867 2771565 complement(1186051..1186350) 1 NC_005823.1 hypothetical protein 1186350 2771565 LIC10979 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000953.1 1186051 R 267671 CDS YP_000954.1 45656868 2770064 complement(1186497..1187342) 1 NC_005823.1 transposase, IS1501 1187342 2770064 LIC10980 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, IS1501 YP_000954.1 1186497 R 267671 CDS YP_000955.1 45656869 2771236 complement(1187339..1187644) 1 NC_005823.1 transposase, IS1501 1187644 2771236 LIC10981 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, IS1501 YP_000955.1 1187339 R 267671 CDS YP_000956.1 45656870 2770511 complement(1187747..1188652) 1 NC_005823.1 DMT; identified by sequence similarity; ORF located using Blastx/Glimmer; DMT family permease 1188652 2770511 LIC10982 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DMT family permease YP_000956.1 1187747 R 267671 CDS YP_000957.1 45656871 2772337 complement(1188652..1190172) 1 NC_005823.1 carboxypeptidase T 1190172 cpt 2772337 cpt Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 carboxypeptidase T YP_000957.1 1188652 R 267671 CDS YP_000958.1 45656872 2771181 1190243..1191211 1 NC_005823.1 hypothetical protein 1191211 2771181 LIC10984 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000958.1 1190243 D 267671 CDS YP_000959.1 45656873 2770878 1191213..1192274 1 NC_005823.1 hypothetical protein 1192274 2770878 LIC10985 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000959.1 1191213 D 267671 CDS YP_000960.1 45656874 2771931 complement(1193054..1193473) 1 NC_005823.1 hypothetical protein 1193473 2771931 LIC10986 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000960.1 1193054 R 267671 CDS YP_000961.1 45656875 2771240 1194725..1195648 1 NC_005823.1 hypothetical protein 1195648 2771240 LIC10987 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000961.1 1194725 D 267671 CDS YP_000962.1 45656876 2771472 1195745..1197808 1 NC_005823.1 hypothetical protein 1197808 2771472 LIC10988 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000962.1 1195745 D 267671 CDS YP_000963.1 45656877 2770245 1198009..1203204 1 NC_005823.1 serine/threonine kinase protein 1203204 2770245 LIC10989 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 serine/threonine kinase protein YP_000963.1 1198009 D 267671 CDS YP_000964.1 45656878 2772613 1203450..1205123 1 NC_005823.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 1205123 kdpA 2772613 kdpA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 potassium-transporting ATPase subunit A YP_000964.1 1203450 D 267671 CDS YP_000965.1 45656879 2772244 1205134..1207212 1 NC_005823.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 1207212 kdpB 2772244 kdpB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 potassium-transporting ATPase subunit B YP_000965.1 1205134 D 267671 CDS YP_000966.1 45656880 2771586 1207223..1207795 1 NC_005823.1 potassium-transporting ATPase subunit C 1207795 kdpC 2771586 kdpC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 potassium-transporting ATPase subunit C YP_000966.1 1207223 D 267671 CDS YP_000967.1 45656881 2771987 1207792..1210404 1 NC_005823.1 histidine kinase sensor protein 1210404 kdpD 2771987 kdpD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_000967.1 1207792 D 267671 CDS YP_000968.1 45656882 2770502 1210408..1211091 1 NC_005823.1 response regulator 1211091 kdpE 2770502 kdpE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_000968.1 1210408 D 267671 CDS YP_000969.1 45656883 2772660 complement(1211402..1212526) 1 NC_005823.1 hypothetical protein 1212526 2772660 LIC10995 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000969.1 1211402 R 267671 CDS YP_000970.1 45656884 2772526 1213530..1214423 1 NC_005823.1 EAL domain; identified by sequence similarity; ORF located using Blastx/Glimmer; diguanylate phosphodiesterase 1214423 2772526 LIC10996 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 diguanylate phosphodiesterase YP_000970.1 1213530 D 267671 CDS YP_000971.1 45656885 2772815 1214849..1215319 1 NC_005823.1 hypothetical protein 1215319 2772815 LIC10997 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000971.1 1214849 D 267671 CDS YP_000972.1 45656886 2772597 1215388..1216986 1 NC_005823.1 hypothetical protein 1216986 2772597 LIC10998 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000972.1 1215388 D 267671 CDS YP_000973.1 45656887 2770140 complement(1217077..1218069) 1 NC_005823.1 hypothetical protein 1218069 2770140 LIC10999 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000973.1 1217077 R 267671 CDS YP_000974.1 45656888 2772397 1218493..1219404 1 NC_005823.1 short-chain dehydrogenase 1219404 2772397 LIC11000 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 short-chain dehydrogenase YP_000974.1 1218493 D 267671 CDS YP_000975.1 45656889 2772766 1219982..1220170 1 NC_005823.1 IS1533 transposase 1220170 2772766 LIC11002 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 IS1533 transposase YP_000975.1 1219982 D 267671 CDS YP_000976.1 45656890 2771260 complement(1220930..1222597) 1 NC_005823.1 lipoprotein; hypothetical protein 1222597 lipL71 2771260 lipL71 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000976.1 1220930 R 267671 CDS YP_000977.1 45656891 2772619 complement(1222645..1222980) 1 NC_005823.1 anti-sigma factor antagonist 1222980 2772619 LIC11004 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_000977.1 1222645 R 267671 CDS YP_000978.1 45656892 2772479 complement(1223051..1224175) 1 NC_005823.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1224175 tgt 2772479 tgt Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 queuine tRNA-ribosyltransferase YP_000978.1 1223051 R 267671 CDS YP_000979.1 45656893 2771174 complement(1224172..1224654) 1 NC_005823.1 Fur family transcriptional regulator 1224654 2771174 LIC11006 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Fur family transcriptional regulator YP_000979.1 1224172 R 267671 CDS YP_000980.1 45656894 2770076 complement(1224685..1225245) 1 NC_005823.1 hypothetical protein 1225245 2770076 LIC11007 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000980.1 1224685 R 267671 CDS YP_000981.1 45656895 2771207 1225277..1227088 1 NC_005823.1 hypothetical protein 1227088 2771207 LIC11008 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000981.1 1225277 D 267671 CDS YP_000982.1 45656896 2771445 complement(1227933..1228682) 1 NC_005823.1 hypothetical protein 1228682 2771445 LIC11009 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000982.1 1227933 R 267671 CDS YP_000983.1 45656897 2769879 1233034..1233948 1 NC_005823.1 nicotinate-nucleotide pyrophosphorylase 1233948 nadC 2769879 nadC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 nicotinate-nucleotide pyrophosphorylase YP_000983.1 1233034 D 267671 CDS YP_000984.1 45656898 2771313 1233953..1235977 1 NC_005823.1 guanosine polyphosphate pyrophosphohydrolase/synthetase 1235977 2771313 LIC11012 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 guanosine polyphosphate pyrophosphohydrolase/synthetase YP_000984.1 1233953 D 267671 CDS YP_000985.1 45656899 2771665 1235991..1237790 1 NC_005823.1 ABC transporter, nickel-binding periplasmic protein precursor; hypothetical protein 1237790 oppA 2771665 oppA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000985.1 1235991 D 267671 CDS YP_000986.1 45656900 2770115 1237801..1238868 1 NC_005823.1 hypothetical protein 1238868 2770115 LIC11014 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000986.1 1237801 D 267671 CDS YP_000987.1 45656901 2772086 1239389..1239592 1 NC_005823.1 hypothetical protein 1239592 2772086 LIC11015 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000987.1 1239389 D 267671 CDS YP_000988.1 45656902 2772561 1239567..1240868 1 NC_005823.1 adenylosuccinate lyase 1240868 purB 2772561 purB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylosuccinate lyase YP_000988.1 1239567 D 267671 CDS YP_000989.1 45656903 2772813 1240869..1241651 1 NC_005823.1 hypothetical protein 1241651 2772813 LIC11017 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000989.1 1240869 D 267671 CDS YP_000990.1 45656904 2772806 1243849..1244667 1 NC_005823.1 sterol desaturase 1244667 pio75 2772806 pio75 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sterol desaturase YP_000990.1 1243849 D 267671 CDS YP_000991.1 45656905 2772197 complement(1244705..1245229) 1 NC_005823.1 lipoprotein 1245229 2772197 LIC11019 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_000991.1 1244705 R 267671 CDS YP_000992.1 45656906 2771637 complement(1245217..1245603) 1 NC_005823.1 hypothetical protein 1245603 2771637 LIC11020 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000992.1 1245217 R 267671 CDS YP_000993.1 45656907 2770244 complement(1253446..1255326) 1 NC_005823.1 hypothetical protein 1255326 2770244 LIC11023 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000993.1 1253446 R 267671 CDS YP_000994.1 45656908 2771508 complement(1255359..1256354) 1 NC_005823.1 glycosyltransferase 1256354 2771508 LIC11024 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyltransferase YP_000994.1 1255359 R 267671 CDS YP_000995.1 45656909 2770204 1256532..1256873 1 NC_005823.1 anti-sigma factor antagonist 1256873 2770204 LIC11025 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_000995.1 1256532 D 267671 CDS YP_000996.1 45656910 2771914 1256897..1259905 1 NC_005823.1 hypothetical protein 1259905 2771914 LIC11026 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000996.1 1256897 D 267671 CDS YP_000997.1 45656911 2772861 1259919..1260515 1 NC_005823.1 hypothetical protein 1260515 2772861 LIC11027 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000997.1 1259919 D 267671 CDS YP_000998.1 45656912 2769765 1260519..1268285 1 NC_005823.1 internal repeat sequences detected; contains TPR domain as detected by pfam-hmmr; hypothetical protein 1268285 2769765 LIC11028 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000998.1 1260519 D 267671 CDS YP_000999.1 45656913 2769775 complement(1268775..1269086) 1 NC_005823.1 hypothetical protein 1269086 2769775 LIC11029 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_000999.1 1268775 R 267671 CDS YP_001000.1 45656914 2770022 complement(1269359..1270393) 1 NC_005823.1 lipoprotein 1270393 2770022 LIC11030 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001000.1 1269359 R 267671 CDS YP_001001.1 45656915 2771360 1271385..1271780 1 NC_005823.1 transposase, ISlin1 1271780 2771360 LIC11031 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_001001.1 1271385 D 267671 CDS YP_001002.1 45656916 2771073 1271749..1272663 1 NC_005823.1 transposase, ISlin1 1272663 2771073 LIC11032 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_001002.1 1271749 D 267671 CDS YP_001003.1 45656917 2769602 1272711..1272899 1 NC_005823.1 hypothetical protein 1272899 2769602 LIC11033 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001003.1 1272711 D 267671 CDS YP_001004.1 45656918 2769586 complement(1273560..1274459) 1 NC_005823.1 hypothetical protein 1274459 2769586 LIC11034 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001004.1 1273560 R 267671 CDS YP_001005.1 45656919 2771758 complement(1274487..1274864) 1 NC_005823.1 hypothetical protein 1274864 2771758 LIC11035 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001005.1 1274487 R 267671 CDS YP_001006.1 45656920 2769484 complement(1274891..1275997) 1 NC_005823.1 hypothetical protein 1275997 2769484 LIC11036 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001006.1 1274891 R 267671 CDS YP_001007.1 45656921 2769510 1275996..1277093 1 NC_005823.1 periplasmic trypsin-like serine protease 1277093 htrA 2769510 htrA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 periplasmic trypsin-like serine protease YP_001007.1 1275996 D 267671 CDS YP_001008.1 45656922 2769558 1277134..1278438 1 NC_005823.1 aminotransferase 1278438 2769558 LIC11038 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aminotransferase YP_001008.1 1277134 D 267671 CDS YP_001009.1 45656923 2769539 1278471..1279241 1 NC_005823.1 glutamate racemase 1279241 murI 2769539 murI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutamate racemase YP_001009.1 1278471 D 267671 CDS YP_001010.1 45656924 2769621 1279584..1280303 1 NC_005823.1 SphN-like protein; hemolysin 1280303 2769621 LIC11040 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hemolysin YP_001010.1 1279584 D 267671 CDS YP_001011.1 45656925 2770580 complement(1280406..1280828) 1 NC_005823.1 hypothetical protein 1280828 2770580 LIC11041 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001011.1 1280406 R 267671 CDS YP_001012.1 45656926 2770055 complement(1282369..1282917) 1 NC_005823.1 internal repeat sequences detected; contains Ankyrin repeat as detected by pfam-hmmr; hypothetical protein 1282917 2770055 LIC11042 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001012.1 1282369 R 267671 CDS YP_001013.1 45656927 2772406 complement(1282914..1283306) 1 NC_005823.1 hypothetical protein 1283306 2772406 LIC11043 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001013.1 1282914 R 267671 CDS YP_001014.1 45656928 2772844 complement(1283897..1284412) 1 NC_005823.1 hypothetical protein 1284412 2772844 LIC11044 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001014.1 1283897 R 267671 CDS YP_001015.1 45656929 2772522 complement(1284628..1285884) 1 NC_005823.1 adenylate or guanylate cyclase 1285884 2772522 LIC11045 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate or guanylate cyclase YP_001015.1 1284628 R 267671 CDS YP_001016.1 45656930 2771836 1286646..1287848 1 NC_005823.1 hypothetical protein 1287848 2771836 LIC11046 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001016.1 1286646 D 267671 CDS YP_001017.1 45656931 2770555 1288058..1288627 1 NC_005823.1 hypothetical protein 1288627 2770555 LIC11047 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001017.1 1288058 D 267671 CDS YP_001018.1 45656932 2771416 complement(1289141..1289971) 1 NC_005823.1 molybdate metabolism regulator 1289971 2771416 LIC11048 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 molybdate metabolism regulator YP_001018.1 1289141 R 267671 CDS YP_001019.1 45656933 2771272 complement(1290179..1291135) 1 NC_005823.1 hypothetical protein 1291135 2771272 LIC11049 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001019.1 1290179 R 267671 CDS YP_001020.1 45656934 2770477 1291814..1293163 1 NC_005823.1 ankyrin 1293163 ank3 2770477 ank3 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ankyrin YP_001020.1 1291814 D 267671 CDS YP_001021.1 45656935 2772176 complement(1293343..1295400) 1 NC_005823.1 internal repeat sequences detected; contains leucine-rich repeat as detected by pfam-hmmr; hypothetical protein 1295400 2772176 LIC11051 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001021.1 1293343 R 267671 CDS YP_001022.1 45656936 2771499 1296350..1297447 1 NC_005823.1 hypothetical protein 1297447 2771499 LIC11052 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001022.1 1296350 D 267671 CDS YP_001023.1 45656937 2772621 complement(1298134..1298796) 1 NC_005823.1 hypothetical protein 1298796 2772621 LIC11053 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001023.1 1298134 R 267671 CDS YP_001024.1 45656938 2772331 1299824..1300234 1 NC_005823.1 hypothetical protein 1300234 2772331 LIC11054 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001024.1 1299824 D 267671 CDS YP_001025.1 45656939 2772474 complement(1300352..1301146) 1 NC_005823.1 hypothetical protein 1301146 2772474 LIC11055 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001025.1 1300352 R 267671 CDS YP_001026.1 45656940 2771122 complement(1301205..1301768) 1 NC_005823.1 hypothetical protein 1301768 2771122 LIC11056 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001026.1 1301205 R 267671 CDS YP_001027.1 45656941 2772218 complement(1301784..1303154) 1 NC_005823.1 internal repeat sequences detected; contains DUF477 domain as detected by pfam-hmmr; hypothetical protein 1303154 2772218 LIC11057 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001027.1 1301784 R 267671 CDS YP_001028.1 45656942 2772411 complement(1303317..1303913) 1 NC_005823.1 lipoprotein 1303913 lemA 2772411 lemA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001028.1 1303317 R 267671 CDS YP_001029.1 45656943 2770004 complement(1303980..1304252) 1 NC_005823.1 hypothetical protein 1304252 2770004 LIC11059 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001029.1 1303980 R 267671 CDS YP_001030.1 45656944 2771256 complement(1305290..1306660) 1 NC_005823.1 hypothetical protein 1306660 2771256 LIC11060 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001030.1 1305290 R 267671 CDS YP_001031.1 45656945 2769994 1306896..1309742 1 NC_005823.1 cell division protein 1309742 ftsK 2769994 ftsK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cell division protein YP_001031.1 1306896 D 267671 CDS YP_001032.1 45656946 2772128 1311361..1311984 1 NC_005823.1 hypothetical protein 1311984 2772128 LIC11062 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001032.1 1311361 D 267671 CDS YP_001033.1 45656947 2771871 complement(1312650..1313606) 1 NC_005823.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1313606 lgt 2771871 lgt Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 prolipoprotein diacylglyceryl transferase YP_001033.1 1312650 R 267671 CDS YP_001034.1 45656948 2771502 complement(1314005..1315021) 1 NC_005823.1 membrane associated metalloendopeptidase 1315021 2771502 LIC11064 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 membrane associated metalloendopeptidase YP_001034.1 1314005 R 267671 CDS YP_001035.2 304570488 2772714 1315075..1316538 1 NC_005823.1 polynucleotide adenyltransferase; poly A polymerase 1316538 pcnB 2772714 pcnB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 poly A polymerase YP_001035.2 1315075 D 267671 CDS YP_001036.1 45656950 2772180 complement(1317692..1319623) 1 NC_005823.1 single-stranded DNA exonuclease 1319623 recJ 2772180 recJ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 single-stranded DNA exonuclease YP_001036.1 1317692 R 267671 CDS YP_001037.1 45656951 2771037 complement(1319626..1319946) 1 NC_005823.1 internal repeat sequences detected; contains DUF583 domain as detected by pfam-hmmr; hypothetical protein 1319946 2771037 LIC11067 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001037.1 1319626 R 267671 CDS YP_001038.1 45656952 2772296 complement(1320583..1321314) 1 NC_005823.1 lysozyme precursor 1321314 2772296 LIC11068 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lysozyme precursor YP_001038.1 1320583 R 267671 CDS YP_001039.1 45656953 2772557 1321902..1322321 1 NC_005823.1 hypothetical protein 1322321 2772557 LIC11069 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001039.1 1321902 D 267671 CDS YP_001040.1 45656954 2771917 complement(1322318..1323484) 1 NC_005823.1 alcohol dehydrogenase 1323484 2771917 LIC11070 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alcohol dehydrogenase YP_001040.1 1322318 R 267671 CDS YP_001041.1 45656955 2770916 complement(1323561..1323884) 1 NC_005823.1 hypothetical protein 1323884 2770916 LIC11071 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001041.1 1323561 R 267671 CDS YP_001042.1 45656956 2770563 complement(1323897..1324649) 1 NC_005823.1 tetrapyrrole (corrin/porphyrin) methylase 1324649 2770563 LIC11072 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tetrapyrrole (corrin/porphyrin) methylase YP_001042.1 1323897 R 267671 CDS YP_001043.1 45656957 2772347 complement(1324646..1325416) 1 NC_005823.1 lipoprotein 1325416 2772347 LIC11073 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001043.1 1324646 R 267671 CDS YP_001044.1 45656958 2772105 1325501..1326199 1 NC_005823.1 hypothetical protein 1326199 2772105 LIC11074 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001044.1 1325501 D 267671 CDS YP_001045.1 45656959 2772488 complement(1327258..1329186) 1 NC_005823.1 NH(3)-dependent NAD(+) synthetase 1329186 nadE 2772488 nadE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NH(3)-dependent NAD(+) synthetase YP_001045.1 1327258 R 267671 CDS YP_001046.1 45656960 2770220 1329282..1329866 1 NC_005823.1 uridine 5-monophosphate synthase 1329866 pyrE 2770220 pyrE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 uridine 5-monophosphate synthase YP_001046.1 1329282 D 267671 CDS YP_001047.1 45656961 2771083 1329838..1330566 1 NC_005823.1 hypothetical protein 1330566 2771083 LIC11077 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001047.1 1329838 D 267671 CDS YP_001048.1 45656962 2772190 complement(1330614..1331306) 1 NC_005823.1 hypothetical protein 1331306 2772190 LIC11078 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001048.1 1330614 R 267671 CDS YP_001049.1 45656963 2771503 complement(1332138..1333049) 1 NC_005823.1 hypothetical protein 1333049 2771503 LIC11079 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001049.1 1332138 R 267671 CDS YP_001050.1 45656964 2770258 complement(1333110..1335584) 1 NC_005823.1 ABC transporter 1335584 2770258 LIC11080 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter YP_001050.1 1333110 R 267671 CDS YP_001051.1 45656965 2771211 complement(1335590..1336285) 1 NC_005823.1 ABC transporter ATP-binding protein 1336285 2771211 LIC11081 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_001051.1 1335590 R 267671 CDS YP_001052.1 45656966 2771370 complement(1337006..1338130) 1 NC_005823.1 hypothetical protein 1338130 2771370 LIC11082 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001052.1 1337006 R 267671 CDS YP_001053.1 45656967 2772670 complement(1338127..1338399) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 1338399 2772670 LIC11083 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001053.1 1338127 R 267671 CDS YP_001054.1 45656968 2771305 1338573..1339718 1 NC_005823.1 hypothetical protein 1339718 2771305 LIC11084 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001054.1 1338573 D 267671 CDS YP_001055.1 45656969 2772881 complement(1340307..1341671) 1 NC_005823.1 RNA methyltransferase 1341671 2772881 LIC11085 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA methyltransferase YP_001055.1 1340307 R 267671 CDS YP_001056.1 45656970 2772922 complement(1341853..1342839) 1 NC_005823.1 hypothetical protein 1342839 2772922 LIC11086 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001056.1 1341853 R 267671 CDS YP_001057.1 45656971 2771413 complement(1342839..1343717) 1 NC_005823.1 lipoprotein 1343717 2771413 LIC11087 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001057.1 1342839 R 267671 CDS YP_001058.1 45656972 2771928 complement(1343689..1344888) 1 NC_005823.1 methylamine utilization protein; cytochrome c peroxidase 1344888 2771928 LIC11088 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytochrome c peroxidase YP_001058.1 1343689 R 267671 CDS YP_001059.1 45656973 2772941 complement(1344935..1345882) 1 NC_005823.1 hypothetical protein 1345882 2772941 LIC11089 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001059.1 1344935 R 267671 CDS YP_001060.1 45656974 2772879 complement(1345998..1346435) 1 NC_005823.1 lipoprotein 1346435 2772879 LIC11090 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001060.1 1345998 R 267671 CDS YP_001061.1 45656975 2771956 complement(1346432..1346917) 1 NC_005823.1 hypothetical protein 1346917 2771956 LIC11091 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001061.1 1346432 R 267671 CDS YP_001062.1 45656976 2771442 1347036..1348934 1 NC_005823.1 hypothetical protein 1348934 2771442 LIC11092 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001062.1 1347036 D 267671 CDS YP_001063.1 45656977 2772706 1349308..1350201 1 NC_005823.1 glycosyl transferase 1350201 2772706 LIC11093 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyl transferase YP_001063.1 1349308 D 267671 CDS YP_001064.1 45656978 2772697 1350697..1350882 1 NC_005823.1 hypothetical protein 1350882 2772697 LIC11094 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001064.1 1350697 D 267671 CDS YP_001065.1 45656979 2770881 1351221..1352327 1 NC_005823.1 adenylate/guanylate cyclase 1352327 2770881 LIC11095 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_001065.1 1351221 D 267671 CDS YP_001066.1 45656980 2770398 complement(1352324..1352638) 1 NC_005823.1 hypothetical protein 1352638 2770398 LIC11096 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001066.1 1352324 R 267671 CDS YP_001067.1 45656981 2772688 complement(1352635..1353876) 1 NC_005823.1 contains leucine-rich repeats; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 1353876 2772688 LIC11097 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001067.1 1352635 R 267671 CDS YP_001068.1 45656982 2771611 complement(1353873..1355153) 1 NC_005823.1 internal repeat sequences detected; contains Leucine rich repeat as detected by pfam-hmmr; hypothetical protein 1355153 2771611 LIC11098 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001068.1 1353873 R 267671 CDS YP_001069.1 45656983 2772238 complement(1355515..1356066) 1 NC_005823.1 hypothetical protein 1356066 2772238 LIC11099 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001069.1 1355515 R 267671 CDS YP_001070.1 45656984 2770961 1357320..1357508 1 NC_005823.1 hypothetical protein 1357508 2770961 LIC11100 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001070.1 1357320 D 267671 CDS YP_001071.1 45656985 2772663 1357501..1359183 1 NC_005823.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 1359183 ilvD 2772663 ilvD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dihydroxy-acid dehydratase YP_001071.1 1357501 D 267671 CDS YP_001072.1 45656986 2770195 complement(1359655..1359855) 1 NC_005823.1 hypothetical protein 1359855 2770195 LIC11102 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001072.1 1359655 R 267671 CDS YP_001073.1 45656987 2772439 complement(1360478..1361611) 1 NC_005823.1 alpha/beta fold family hydrolase 1361611 2772439 LIC11103 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alpha/beta fold family hydrolase YP_001073.1 1360478 R 267671 CDS YP_001074.1 45656988 2772222 complement(1362607..1363278) 1 NC_005823.1 P or Q; identified by sequence similarity; ORF located using Blastx/Glimmer; aminopeptidase 1363278 2772222 LIC11104 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aminopeptidase YP_001074.1 1362607 R 267671 CDS YP_001075.1 45656989 2772614 complement(1363559..1366936) 1 NC_005823.1 methylmalonyl-CoA mutase 1366936 mcm1 2772614 mcm1 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methylmalonyl-CoA mutase YP_001075.1 1363559 R 267671 CDS YP_001076.1 45656990 2771339 complement(1366973..1367770) 1 NC_005823.1 acyltransferase 1367770 plsC 2771339 plsC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyltransferase YP_001076.1 1366973 R 267671 CDS YP_001077.1 45656991 2772637 1368007..1368972 1 NC_005823.1 phosphatidylglycerophosphatase B 1368972 pgpB 2772637 pgpB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphatidylglycerophosphatase B YP_001077.1 1368007 D 267671 CDS YP_001078.1 45656992 2772797 1368974..1370260 1 NC_005823.1 polysaccharide exporter 1370260 2772797 LIC11108 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 polysaccharide exporter YP_001078.1 1368974 D 267671 CDS YP_001079.1 45656993 2772153 1370257..1371969 1 NC_005823.1 hypothetical protein 1371969 2772153 LIC11109 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001079.1 1370257 D 267671 CDS YP_001080.1 45656994 2772282 complement(1371949..1372863) 1 NC_005823.1 histidine kinase response regulator hybrid protein 1372863 2772282 LIC11110 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase response regulator hybrid protein YP_001080.1 1371949 R 267671 CDS YP_001081.1 45656995 2772096 complement(1372900..1374237) 1 NC_005823.1 protease; identified by sequence similarity; ORF located using Blastx/Glimmer; HtrA2 1374237 htrA2 2772096 htrA2 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 HtrA2 YP_001081.1 1372900 R 267671 CDS YP_001082.1 45656996 2772683 complement(1374234..1375688) 1 NC_005823.1 HtrA-like; identified by sequence similarity; ORF located using Blastx/Glimmer; serine protease 1375688 2772683 LIC11112 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 serine protease YP_001082.1 1374234 R 267671 CDS YP_001083.1 45656997 2772781 complement(1375681..1376544) 1 NC_005823.1 hypothetical protein 1376544 2772781 LIC11113 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001083.1 1375681 R 267671 CDS YP_001084.1 45656998 2771864 1376518..1376712 1 NC_005823.1 hypothetical protein 1376712 2771864 LIC11114 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001084.1 1376518 D 267671 CDS YP_001085.1 45656999 2772847 1376758..1377615 1 NC_005823.1 thiosulfate sulfurtransferase 1377615 sseA 2772847 sseA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thiosulfate sulfurtransferase YP_001085.1 1376758 D 267671 CDS YP_001086.1 45657000 2770093 1377814..1378308 1 NC_005823.1 hypothetical protein 1378308 2770093 LIC11116 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001086.1 1377814 D 267671 CDS YP_001087.1 45657001 2772530 1378405..1380564 1 NC_005823.1 alpha-glucosidase 1380564 malZ 2772530 malZ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alpha-glucosidase YP_001087.1 1378405 D 267671 CDS YP_001088.1 45657002 2772704 1380629..1381045 1 NC_005823.1 hypothetical protein 1381045 2772704 LIC11118 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001088.1 1380629 D 267671 CDS YP_001089.1 45657003 2772851 complement(1381452..1382687) 1 NC_005823.1 internal repeat sequences detected; contains Kelch motif as detected by pfam-hmmr; hypothetical protein 1382687 2772851 LIC11119 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001089.1 1381452 R 267671 CDS YP_001090.1 45657004 2771547 1383277..1383579 1 NC_005823.1 hypothetical protein 1383579 2771547 LIC11120 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001090.1 1383277 D 267671 CDS YP_001091.1 45657005 2771321 1383576..1384616 1 NC_005823.1 hypothetical protein 1384616 2771321 LIC11121 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001091.1 1383576 D 267671 CDS YP_001092.1 45657006 2770239 1386042..1386650 1 NC_005823.1 lipoprotein 1386650 2770239 LIC11122 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001092.1 1386042 D 267671 CDS YP_001093.1 45657007 2769762 1386807..1387808 1 NC_005823.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 1387808 purM 2769762 purM Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoribosylaminoimidazole synthetase YP_001093.1 1386807 D 267671 CDS YP_001094.1 45657008 2770350 1387819..1389069 1 NC_005823.1 chloride channel 1389069 2770350 LIC11124 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chloride channel YP_001094.1 1387819 D 267671 CDS YP_001095.1 45657009 2771745 complement(1389130..1390092) 1 NC_005823.1 GGDEF family protein 1390092 2771745 LIC11125 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GGDEF family protein YP_001095.1 1389130 R 267671 CDS YP_001096.1 45657010 2769552 complement(1390199..1391134) 1 NC_005823.1 GGDEF family protein 1391134 2769552 LIC11126 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GGDEF family protein YP_001096.1 1390199 R 267671 CDS YP_001097.1 45657011 2769551 complement(1391208..1392149) 1 NC_005823.1 GGDEF family protein 1392149 2769551 LIC11127 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GGDEF family protein YP_001097.1 1391208 R 267671 CDS YP_001098.1 45657012 2769667 complement(1392236..1393162) 1 NC_005823.1 GGDEF family protein 1393162 2769667 LIC11128 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GGDEF family protein YP_001098.1 1392236 R 267671 CDS YP_001099.1 45657013 2771876 complement(1393186..1394139) 1 NC_005823.1 GGDEF family protein 1394139 2771876 LIC11129 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GGDEF family protein YP_001099.1 1393186 R 267671 CDS YP_001100.1 45657014 2771994 complement(1394159..1395106) 1 NC_005823.1 GGDEF family protein 1395106 2771994 LIC11130 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GGDEF family protein YP_001100.1 1394159 R 267671 CDS YP_001101.1 45657015 2771095 complement(1395227..1396186) 1 NC_005823.1 GGDEF family protein 1396186 2771095 LIC11131 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GGDEF family protein YP_001101.1 1395227 R 267671 CDS YP_001102.2 304570489 2772607 complement(1397604..1399031) 1 NC_005823.1 pyruvate kinase 1399031 pykA 2772607 pykA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pyruvate kinase YP_001102.2 1397604 R 267671 CDS YP_001104.2 304570490 2770080 1399134..1400042 1 NC_005823.1 AcuC/AphA family; identified by sequence similarity; ORF located using Blastx/Glimmer; histone deacetylase 1400042 2770080 LIC11134 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histone deacetylase YP_001104.2 1399134 D 267671 CDS YP_001105.1 45657019 2772144 1400045..1400860 1 NC_005823.1 hypothetical protein 1400860 2772144 LIC11135 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001105.1 1400045 D 267671 CDS YP_001106.1 45657020 2771342 1400862..1401971 1 NC_005823.1 response regulator 1401971 2771342 LIC11136 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_001106.1 1400862 D 267671 CDS YP_001107.1 45657021 2772341 1402166..1403341 1 NC_005823.1 hypothetical protein 1403341 2772341 LIC11137 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001107.1 1402166 D 267671 CDS YP_001108.1 45657022 2771501 complement(1403382..1404887) 1 NC_005823.1 hypothetical protein 1404887 2771501 LIC11138 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001108.1 1403382 R 267671 CDS YP_001109.1 45657023 2771054 complement(1405220..1405762) 1 NC_005823.1 hypothetical protein 1405762 2771054 LIC11139 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001109.1 1405220 R 267671 CDS YP_001110.1 45657024 2772856 complement(1405759..1407699) 1 NC_005823.1 alpha-galactosidase 1407699 galA 2772856 galA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alpha-galactosidase YP_001110.1 1405759 R 267671 CDS YP_001111.1 45657025 2771193 1407816..1408454 1 NC_005823.1 ribonuclease D 1408454 2771193 LIC11141 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribonuclease D YP_001111.1 1407816 D 267671 CDS YP_001112.1 45657026 2772332 1408451..1409830 1 NC_005823.1 DNA repair protein; Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 1409830 radA 2772332 radA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA repair protein RadA YP_001112.1 1408451 D 267671 CDS YP_001113.1 45657027 2771528 1410203..1410793 1 NC_005823.1 metal dependent phosphohydrolase 1410793 2771528 LIC11143 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 metal dependent phosphohydrolase YP_001113.1 1410203 D 267671 CDS YP_001114.1 45657028 2772338 complement(1411750..1412139) 1 NC_005823.1 lipoprotein 1412139 2772338 LIC11144 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001114.1 1411750 R 267671 CDS YP_001115.1 45657029 2772589 complement(1412482..1413405) 1 NC_005823.1 short chain dehydrogenase 1413405 2772589 LIC11145 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 short chain dehydrogenase YP_001115.1 1412482 R 267671 CDS YP_001116.1 45657030 2772507 1413750..1414703 1 NC_005823.1 DeoR family transcriptional regulator 1414703 2772507 LIC11146 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DeoR family transcriptional regulator YP_001116.1 1413750 D 267671 CDS YP_001117.1 45657031 2771027 1414978..1415457 1 NC_005823.1 nitrilotriacetate monooxygenase component B 1415457 ntaB 2771027 ntaB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 nitrilotriacetate monooxygenase component B YP_001117.1 1414978 D 267671 CDS YP_001118.1 45657032 2771326 1416118..1416756 1 NC_005823.1 DNA helicase subunit A 1416756 ruvA 2771326 ruvA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA helicase subunit A YP_001118.1 1416118 D 267671 CDS YP_001119.1 45657033 2771701 1418081..1418896 1 NC_005823.1 membrane metalloendopeptidase 1418896 2771701 LIC11149 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 membrane metalloendopeptidase YP_001119.1 1418081 D 267671 CDS YP_001120.1 45657034 2770237 1418897..1419709 1 NC_005823.1 nonspecific acid phosphatase precursor 1419709 2770237 LIC11150 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 nonspecific acid phosphatase precursor YP_001120.1 1418897 D 267671 CDS YP_001121.1 45657035 2771297 1420318..1421043 1 NC_005823.1 hypothetical protein 1421043 2771297 LIC11151 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001121.1 1420318 D 267671 CDS YP_001122.1 45657036 2771899 complement(1421846..1422724) 1 NC_005823.1 pseudouridylate synthase, 23S RNA-specific 1422724 2771899 LIC11152 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pseudouridylate synthase, 23S RNA-specific YP_001122.1 1421846 R 267671 CDS YP_001123.1 45657037 2771481 complement(1422708..1422911) 1 NC_005823.1 hypothetical protein 1422911 2771481 LIC11153 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001123.1 1422708 R 267671 CDS YP_001124.1 45657038 2771588 1423318..1423929 1 NC_005823.1 transcriptional regulator 1423929 2771588 LIC11154 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transcriptional regulator YP_001124.1 1423318 D 267671 CDS YP_001125.1 45657039 2772004 1424320..1425306 1 NC_005823.1 hypothetical protein 1425306 2772004 LIC11155 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001125.1 1424320 D 267671 CDS YP_001126.1 45657040 2771855 complement(1425855..1427324) 1 NC_005823.1 hypothetical protein 1427324 2771855 LIC11156 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001126.1 1425855 R 267671 CDS YP_001127.1 45657041 2772126 complement(1427596..1427841) 1 NC_005823.1 hypothetical protein 1427841 2772126 LIC11157 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001127.1 1427596 R 267671 CDS YP_001128.1 45657042 2770205 1428666..1429103 1 NC_005823.1 Fur family transcriptional regulator 1429103 2770205 LIC11158 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Fur family transcriptional regulator YP_001128.1 1428666 D 267671 CDS YP_001129.1 45657043 2770702 complement(1429100..1430572) 1 NC_005823.1 dihydrolipoamide dehydrogenase 1430572 2770702 LIC11159 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dihydrolipoamide dehydrogenase YP_001129.1 1429100 R 267671 CDS YP_001130.1 45657044 2772286 1430923..1431480 1 NC_005823.1 hypothetical protein 1431480 2772286 LIC11160 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001130.1 1430923 D 267671 CDS YP_001131.1 45657045 2770088 1431985..1432797 1 NC_005823.1 phenazine biosynthesis-like protein 1432797 2770088 LIC11161 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phenazine biosynthesis-like protein YP_001131.1 1431985 D 267671 CDS YP_001132.1 45657046 2771622 1433123..1433656 1 NC_005823.1 hypothetical protein 1433656 2771622 LIC11162 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001132.1 1433123 D 267671 CDS YP_001133.1 45657047 2770089 1433679..1434266 1 NC_005823.1 hypothetical protein 1434266 2770089 LIC11163 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001133.1 1433679 D 267671 CDS YP_001134.1 45657048 2770513 complement(1434458..1434742) 1 NC_005823.1 hypothetical protein 1434742 2770513 LIC11164 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001134.1 1434458 R 267671 CDS YP_001135.1 45657049 2771070 complement(1434838..1435164) 1 NC_005823.1 nucleotidyltransferase 1435164 2771070 LIC11165 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 nucleotidyltransferase YP_001135.1 1434838 R 267671 CDS YP_001136.1 45657050 2772681 complement(1435252..1435995) 1 NC_005823.1 SAM-dependent methyltransferase 1435995 smtA 2772681 smtA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 SAM-dependent methyltransferase YP_001136.1 1435252 R 267671 CDS YP_001137.1 45657051 2771998 1436055..1437209 1 NC_005823.1 lipoprotein 1437209 2771998 LIC11167 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001137.1 1436055 D 267671 CDS YP_001138.1 45657052 2771727 1437284..1437712 1 NC_005823.1 hypothetical protein 1437712 2771727 LIC11168 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001138.1 1437284 D 267671 CDS YP_001139.1 45657053 2772463 complement(1437785..1438438) 1 NC_005823.1 hypothetical protein 1438438 2772463 LIC11169 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001139.1 1437785 R 267671 CDS YP_001140.1 45657054 2770219 complement(1438469..1438762) 1 NC_005823.1 hypothetical protein 1438762 2770219 LIC11170 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001140.1 1438469 R 267671 CDS YP_001141.1 45657055 2770705 1439445..1440713 1 NC_005823.1 hypothetical protein 1440713 2770705 LIC11171 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001141.1 1439445 D 267671 CDS YP_001142.1 45657056 2770496 1440744..1441859 1 NC_005823.1 hypothetical protein 1441859 2770496 LIC11172 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001142.1 1440744 D 267671 CDS YP_001143.1 45657057 2771788 1442153..1443652 1 NC_005823.1 hypothetical protein 1443652 2771788 LIC11173 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001143.1 1442153 D 267671 CDS YP_001144.1 45657058 2772859 complement(1443941..1444138) 1 NC_005823.1 hypothetical protein 1444138 2772859 LIC11174 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001144.1 1443941 R 267671 CDS YP_001145.1 45657059 2771777 complement(1444815..1445909) 1 NC_005823.1 IF-2B; translation initiation factor 1445909 eif 2771777 eif Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 translation initiation factor YP_001145.1 1444815 R 267671 CDS YP_001146.1 45657060 2772903 1445966..1447033 1 NC_005823.1 contains rhomboid domain; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 1447033 2772903 LIC11176 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001146.1 1445966 D 267671 CDS YP_001147.1 45657061 2769713 1447238..1447702 1 NC_005823.1 hypothetical protein 1447702 2769713 LIC11177 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001147.1 1447238 D 267671 CDS YP_001148.1 45657062 2770229 complement(1447934..1448836) 1 NC_005823.1 hypothetical protein 1448836 2770229 LIC11178 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001148.1 1447934 R 267671 CDS YP_001149.1 45657063 2769768 1450318..1450851 1 NC_005823.1 rhodanese-related thiosulfate sulfurtransferase 1450851 2769768 LIC11179 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 rhodanese-related thiosulfate sulfurtransferase YP_001149.1 1450318 D 267671 CDS YP_001150.1 45657064 2772875 1450848..1451714 1 NC_005823.1 contains leucine rich-repeats; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 1451714 lrr 2772875 lrr Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001150.1 1450848 D 267671 CDS YP_001151.1 45657065 2769781 1452607..1453743 1 NC_005823.1 hypothetical protein 1453743 2769781 LIC11181 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001151.1 1452607 D 267671 CDS YP_001152.1 45657066 2769503 1453795..1454316 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 1454316 2769503 LIC11182 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001152.1 1453795 D 267671 CDS YP_001153.1 45657067 2769488 complement(1455096..1456142) 1 NC_005823.1 hypothetical protein 1456142 2769488 LIC11183 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001153.1 1455096 R 267671 CDS YP_001154.1 45657068 2769714 1457272..1457871 1 NC_005823.1 lipoprotein 1457871 2769714 LIC11184 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001154.1 1457272 D 267671 CDS YP_001155.1 45657069 2769507 1458232..1458942 1 NC_005823.1 hypothetical protein 1458942 2769507 LIC11185 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001155.1 1458232 D 267671 CDS YP_001156.1 45657070 2769592 1460017..1461582 1 NC_005823.1 flagellar protein 1461582 flbC 2769592 flbC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar protein YP_001156.1 1460017 D 267671 CDS YP_001157.1 45657071 2769554 1461597..1462391 1 NC_005823.1 flagellar hook assembly scaffolding protein 1462391 flgD 2769554 flgD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar hook assembly scaffolding protein YP_001157.1 1461597 D 267671 CDS YP_001158.1 45657072 2769811 1462419..1463813 1 NC_005823.1 hook protein; the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1463813 flgE 2769811 flgE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar hook protein FlgE YP_001158.1 1462419 D 267671 CDS YP_001159.1 45657073 2769674 1464048..1466030 1 NC_005823.1 hypothetical protein 1466030 2769674 LIC11189 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001159.1 1464048 D 267671 CDS YP_001160.1 45657074 2772918 complement(1466672..1467145) 1 NC_005823.1 hypothetical protein 1467145 2772918 LIC11190 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001160.1 1466672 R 267671 CDS YP_001161.1 45657075 2770543 1467284..1467580 1 NC_005823.1 transcriptional regulator 1467580 2770543 LIC11191 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transcriptional regulator YP_001161.1 1467284 D 267671 CDS YP_001162.1 45657076 2772937 1468396..1468644 1 NC_005823.1 ChpI 1468644 chpI 2772937 chpI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ChpI YP_001162.1 1468396 D 267671 CDS YP_001163.1 45657077 2770576 1468631..1468951 1 NC_005823.1 ChpK 1468951 chpK 2770576 chpK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ChpK YP_001163.1 1468631 D 267671 CDS YP_001164.1 45657078 2771449 complement(1469951..1470943) 1 NC_005823.1 citrate lyase 1470943 2771449 LIC11194 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 citrate lyase YP_001164.1 1469951 R 267671 CDS YP_001165.1 45657079 2770331 complement(1471083..1472018) 1 NC_005823.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 1472018 argF 2770331 argF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ornithine carbamoyltransferase YP_001165.1 1471083 R 267671 CDS YP_001166.1 45657080 2771091 1472822..1473289 1 NC_005823.1 hypothetical protein 1473289 2771091 LIC11196 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001166.1 1472822 D 267671 CDS YP_001167.1 45657081 2772810 1473286..1473690 1 NC_005823.1 hypothetical protein 1473690 2772810 LIC11197 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001167.1 1473286 D 267671 CDS YP_001168.1 45657082 2771423 1473693..1474964 1 NC_005823.1 adenylate/guanylate cyclase 1474964 2771423 LIC11198 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_001168.1 1473693 D 267671 CDS YP_001169.1 45657083 2770247 1475885..1478155 1 NC_005823.1 cyclic nucleotide binding patatin-like phospholipase 1478155 2770247 LIC11199 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cyclic nucleotide binding patatin-like phospholipase YP_001169.1 1475885 D 267671 CDS YP_001170.1 45657084 2772846 1478223..1480895 1 NC_005823.1 histidine kinase sensor protein 1480895 2772846 LIC11200 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_001170.1 1478223 D 267671 CDS YP_001171.1 45657085 2770840 1480899..1481357 1 NC_005823.1 response regulator 1481357 2770840 LIC11201 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_001171.1 1480899 D 267671 CDS YP_001172.1 45657086 2771900 1481329..1482834 1 NC_005823.1 histidine kinase response regulator hybrid protein 1482834 2771900 LIC11202 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase response regulator hybrid protein YP_001172.1 1481329 D 267671 CDS YP_001173.1 45657087 2770994 1482846..1484060 1 NC_005823.1 response regulator 1484060 2770994 LIC11203 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_001173.1 1482846 D 267671 CDS YP_001174.1 45657088 2769960 complement(1484279..1484545) 1 NC_005823.1 hypothetical protein 1484545 2769960 LIC11204 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001174.1 1484279 R 267671 CDS YP_001175.1 45657089 2769932 1484930..1485697 1 NC_005823.1 hypothetical protein 1485697 2769932 LIC11205 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001175.1 1484930 D 267671 CDS YP_001176.1 45657090 2771945 1486484..1486882 1 NC_005823.1 hypothetical protein 1486882 2771945 LIC11206 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001176.1 1486484 D 267671 CDS YP_001177.1 45657091 2771646 complement(1487116..1488207) 1 NC_005823.1 lipoprotein 1488207 2771646 LIC11207 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001177.1 1487116 R 267671 CDS YP_001178.1 45657092 2771389 complement(1490135..1490539) 1 NC_005823.1 hypothetical protein 1490539 2771389 LIC11209 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001178.1 1490135 R 267671 CDS YP_001179.1 45657093 2770471 1490648..1492678 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 1492678 2770471 LIC11210 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001179.1 1490648 D 267671 CDS YP_001180.1 45657094 2772779 complement(1493811..1494875) 1 NC_005823.1 hypothetical protein 1494875 2772779 LIC11211 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001180.1 1493811 R 267671 CDS YP_001181.1 45657095 2772158 complement(1494872..1495471) 1 NC_005823.1 hypothetical protein 1495471 2772158 LIC11212 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001181.1 1494872 R 267671 CDS YP_001182.1 45657096 2771993 complement(1495441..1495866) 1 NC_005823.1 hypothetical protein 1495866 2771993 LIC11213 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001182.1 1495441 R 267671 CDS YP_001183.1 45657097 2769838 1495839..1496024 1 NC_005823.1 hypothetical protein 1496024 2769838 LIC11214 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001183.1 1495839 D 267671 CDS YP_001184.1 45657098 2771404 complement(1497517..1497780) 1 NC_005823.1 hypothetical protein 1497780 2771404 LIC11215 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001184.1 1497517 R 267671 CDS YP_001185.1 45657099 2771999 1497838..1499562 1 NC_005823.1 methyl-accepting chemotaxis transducer transmembrane protein 1499562 2771999 LIC11216 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methyl-accepting chemotaxis transducer transmembrane protein YP_001185.1 1497838 D 267671 CDS YP_001186.1 45657100 2772350 1499810..1500778 1 NC_005823.1 internal repeat sequences detected; contains DUF789 domain as detected by pfam-hmmr; hypothetical protein 1500778 2772350 LIC11217 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001186.1 1499810 D 267671 CDS YP_001187.1 45657101 2770233 1500989..1501762 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 1501762 2770233 LIC11218 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001187.1 1500989 D 267671 CDS YP_001188.1 45657102 2772533 1502226..1502807 1 NC_005823.1 peroxiredoxin 1502807 ahpC 2772533 ahpC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peroxiredoxin YP_001188.1 1502226 D 267671 CDS YP_001189.1 45657103 2770379 1503299..1504714 1 NC_005823.1 ABC transporter permease 1504714 2770379 LIC11220 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter permease YP_001189.1 1503299 D 267671 CDS YP_001190.1 45657104 2770939 1506718..1510293 1 NC_005823.1 histidine kinase sensor protein 1510293 2770939 LIC11221 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_001190.1 1506718 D 267671 CDS YP_001191.1 45657105 2771974 1510799..1511737 1 NC_005823.1 internal repeat sequences detected; contains TPR domain as detected by pfam-hmmr; hypothetical protein 1511737 2771974 LIC11222 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001191.1 1510799 D 267671 CDS YP_001192.1 45657106 2770855 complement(1511824..1513389) 1 NC_005823.1 hypothetical protein 1513389 2770855 LIC11223 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001192.1 1511824 R 267671 CDS YP_001193.1 45657107 2772726 1513727..1514878 1 NC_005823.1 hypothetical protein 1514878 2772726 LIC11224 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001193.1 1513727 D 267671 CDS YP_001194.1 45657108 2771903 complement(1514927..1515190) 1 NC_005823.1 hypothetical protein 1515190 2771903 LIC11225 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001194.1 1514927 R 267671 CDS YP_001195.1 45657109 2772420 complement(1515532..1515972) 1 NC_005823.1 hypothetical protein 1515972 2772420 LIC11226 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001195.1 1515532 R 267671 CDS YP_001196.1 45657110 2770486 complement(1516730..1517458) 1 NC_005823.1 hypothetical protein 1517458 2770486 LIC11227 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001196.1 1516730 R 267671 CDS YP_001197.1 45657111 2772809 complement(1517473..1518942) 1 NC_005823.1 hypothetical protein 1518942 2772809 LIC11228 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001197.1 1517473 R 267671 CDS YP_001198.1 45657112 2770157 complement(1520105..1521124) 1 NC_005823.1 divalent cation transport-related protein 1521124 yfjQ 2770157 yfjQ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 divalent cation transport-related protein YP_001198.1 1520105 R 267671 CDS YP_001199.1 45657113 2772054 1521989..1524178 1 NC_005823.1 lipoprotein 1524178 2772054 LIC11230 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001199.1 1521989 D 267671 CDS YP_001200.1 45657114 2771136 complement(1525050..1525601) 1 NC_005823.1 TetR family transcriptional regulator 1525601 2771136 LIC11231 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 TetR family transcriptional regulator YP_001200.1 1525050 R 267671 CDS YP_001201.1 45657115 2772840 complement(1525604..1526413) 1 NC_005823.1 hypothetical protein 1526413 2772840 LIC11232 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001201.1 1525604 R 267671 CDS YP_001202.1 45657116 2770413 1526494..1527495 1 NC_005823.1 SPase I; signal peptidase I 1527495 2770413 LIC11233 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 signal peptidase I YP_001202.1 1526494 D 267671 CDS YP_001203.1 45657117 2771947 1527465..1527764 1 NC_005823.1 hypothetical protein 1527764 2771947 LIC11234 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001203.1 1527465 D 267671 CDS YP_001204.1 45657118 2772577 1527974..1528639 1 NC_005823.1 hypothetical protein 1528639 2772577 LIC11235 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001204.1 1527974 D 267671 CDS YP_001205.1 45657119 2770806 1528869..1529198 1 NC_005823.1 hypothetical protein 1529198 2770806 LIC11236 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001205.1 1528869 D 267671 CDS YP_001206.2 229259640 2771257 1529300..1530352 1 NC_005823.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1530352 atpB 2771257 atpB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 F0F1 ATP synthase subunit A YP_001206.2 1529300 D 267671 CDS YP_001207.1 45657121 2771548 1530361..1530687 1 NC_005823.1 ATP synthase C chain 1530687 atpE 2771548 atpE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP synthase C chain YP_001207.1 1530361 D 267671 CDS YP_001208.1 45657122 2772178 1530691..1531212 1 NC_005823.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit B is part of the membrane proton channel; F0F1 ATP synthase subunit B 1531212 atpF 2772178 atpF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 F0F1 ATP synthase subunit B YP_001208.1 1530691 D 267671 CDS YP_001209.1 45657123 2770231 1531217..1531777 1 NC_005823.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1531777 atpH 2770231 atpH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 F0F1 ATP synthase subunit delta YP_001209.1 1531217 D 267671 CDS YP_001210.2 161621777 2771803 1531767..1533278 1 NC_005823.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1533278 atpA 2771803 atpA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 F0F1 ATP synthase subunit alpha YP_001210.2 1531767 D 267671 CDS YP_001211.1 45657125 2771464 1533293..1534153 1 NC_005823.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1534153 atpG 2771464 atpG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 F0F1 ATP synthase subunit gamma YP_001211.1 1533293 D 267671 CDS YP_001212.1 45657126 2772151 1534171..1535574 1 NC_005823.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1535574 atpD 2772151 atpD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 F0F1 ATP synthase subunit beta YP_001212.1 1534171 D 267671 CDS YP_001213.1 45657127 2770603 1535580..1535963 1 NC_005823.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit epsilon 1535963 atpC 2770603 atpC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 F0F1 ATP synthase subunit epsilon YP_001213.1 1535580 D 267671 CDS YP_001214.1 45657128 2772213 1536022..1536327 1 NC_005823.1 internal repeat sequences detected; contains Poly_export domain as detected by pfam-hmmr; hypothetical protein 1536327 2772213 LIC11245 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001214.1 1536022 D 267671 CDS YP_001215.1 45657129 2770252 1536340..1539645 1 NC_005823.1 internal repeat sequences detected; contains MHC_I C-terminus domain as detected by pfam-hmmr; hypothetical protein 1539645 2770252 LIC11246 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001215.1 1536340 D 267671 CDS YP_001216.1 45657130 2770357 1539649..1541805 1 NC_005823.1 cGMP-specific phosphodiesterase 1541805 2770357 LIC11247 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cGMP-specific phosphodiesterase YP_001216.1 1539649 D 267671 CDS YP_001217.1 45657131 2771835 1541817..1543241 1 NC_005823.1 alginate o-acetyltransferase 1543241 2771835 LIC11248 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alginate o-acetyltransferase YP_001217.1 1541817 D 267671 CDS YP_001218.1 45657132 2772555 1543439..1544575 1 NC_005823.1 hypothetical protein 1544575 2772555 LIC11249 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001218.1 1543439 D 267671 CDS YP_001219.1 45657133 2772027 complement(1544712..1545146) 1 NC_005823.1 hypothetical protein 1545146 2772027 LIC11250 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001219.1 1544712 R 267671 CDS YP_001220.1 45657134 2772077 complement(1545597..1545779) 1 NC_005823.1 hypothetical protein 1545779 2772077 LIC11251 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001220.1 1545597 R 267671 CDS YP_001221.1 45657135 2772498 complement(1545848..1546555) 1 NC_005823.1 hypothetical protein 1546555 2772498 LIC11252 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001221.1 1545848 R 267671 CDS YP_001222.1 45657136 2771392 1547237..1547458 1 NC_005823.1 hypothetical protein 1547458 2771392 LIC11253 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001222.1 1547237 D 267671 CDS YP_001223.1 45657137 2772642 complement(1547869..1549134) 1 NC_005823.1 lipoprotein 1549134 2772642 LIC11254 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001223.1 1547869 R 267671 CDS YP_001224.1 45657138 2770432 complement(1550012..1550200) 1 NC_005823.1 hypothetical protein 1550200 2770432 LIC11255 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001224.1 1550012 R 267671 CDS YP_001225.1 45657139 2771178 complement(1551872..1552120) 1 NC_005823.1 hypothetical protein 1552120 2771178 LIC11256 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001225.1 1551872 R 267671 CDS YP_001226.1 45657140 2772370 complement(1552572..1554134) 1 NC_005823.1 exopolyphosphatase 1554134 ppx 2772370 ppx Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 exopolyphosphatase YP_001226.1 1552572 R 267671 CDS YP_001227.1 45657141 2771641 1554326..1555348 1 NC_005823.1 rod shape-determining protein; functions in MreBCD complex in some organisms; rod shape-determining protein MreB 1555348 mreB 2771641 mreB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 rod shape-determining protein MreB YP_001227.1 1554326 D 267671 CDS YP_001228.1 45657142 2771924 1555386..1556519 1 NC_005823.1 rod shape-determining protein; in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 1556519 mreC 2771924 mreC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 rod shape-determining protein MreC YP_001228.1 1555386 D 267671 CDS YP_001229.1 45657143 2772843 1556516..1557028 1 NC_005823.1 rod shape-determining protein; hypothetical protein 1557028 mreD 2772843 mreD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001229.1 1556516 D 267671 CDS YP_001230.1 45657144 2772850 1557030..1558973 1 NC_005823.1 penicillin-binding protein 1558973 2772850 LIC11261 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 penicillin-binding protein YP_001230.1 1557030 D 267671 CDS YP_001231.1 45657145 2772425 1558942..1560465 1 NC_005823.1 rod shape-determining protein; RodA 1560465 rodA 2772425 rodA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RodA YP_001231.1 1558942 D 267671 CDS YP_001232.1 45657146 2770830 1560904..1561686 1 NC_005823.1 hypothetical protein 1561686 2770830 LIC11263 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001232.1 1560904 D 267671 CDS YP_001233.1 45657147 2772860 complement(1562177..1562920) 1 NC_005823.1 hypothetical protein 1562920 2772860 LIC11264 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001233.1 1562177 R 267671 CDS YP_001234.1 45657148 2771235 complement(1563219..1563446) 1 NC_005823.1 hypothetical protein 1563446 2771235 LIC11265 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001234.1 1563219 R 267671 CDS YP_001235.1 45657149 2771334 1563574..1563984 1 NC_005823.1 6-pyruvoyl tetrahydrobiopterin synthase 1563984 2771334 LIC11266 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 6-pyruvoyl tetrahydrobiopterin synthase YP_001235.1 1563574 D 267671 CDS YP_001236.1 45657150 2771955 complement(1565101..1566105) 1 NC_005823.1 periplasmic sulfate-binding protein 1566105 sbp 2771955 sbp Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 periplasmic sulfate-binding protein YP_001236.1 1565101 R 267671 CDS YP_001237.1 45657151 2771610 complement(1566134..1567963) 1 NC_005823.1 hypothetical protein 1567963 2771610 LIC11268 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001237.1 1566134 R 267671 CDS YP_001238.1 45657152 2770726 complement(1568439..1568624) 1 NC_005823.1 hypothetical protein 1568624 2770726 LIC11269 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001238.1 1568439 R 267671 CDS YP_001239.1 45657153 2770653 complement(1570241..1571530) 1 NC_005823.1 hypothetical protein 1571530 2770653 LIC11270 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001239.1 1570241 R 267671 CDS YP_001240.1 45657154 2772268 complement(1571527..1572345) 1 NC_005823.1 hypothetical protein 1572345 2772268 LIC11271 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001240.1 1571527 R 267671 CDS YP_001241.1 45657155 2771205 complement(1573142..1574023) 1 NC_005823.1 hypothetical protein 1574023 2771205 LIC11273 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001241.1 1573142 R 267671 CDS YP_001242.1 45657156 2772648 1574168..1575277 1 NC_005823.1 hypothetical protein 1575277 2772648 LIC11274 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001242.1 1574168 D 267671 CDS YP_001243.1 45657157 2771461 complement(1575267..1575449) 1 NC_005823.1 hypothetical protein 1575449 2771461 LIC11275 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001243.1 1575267 R 267671 CDS YP_001244.1 45657158 2771355 1575657..1576454 1 NC_005823.1 fatty acyltransferase 1576454 2771355 LIC11276 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 fatty acyltransferase YP_001244.1 1575657 D 267671 CDS YP_001245.1 45657159 2772502 1576451..1577914 1 NC_005823.1 acetyl-CoA carboxylase subunit alpha 1577914 accC 2772502 accC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyl-CoA carboxylase subunit alpha YP_001245.1 1576451 D 267671 CDS YP_001246.1 45657160 2772827 1577911..1578411 1 NC_005823.1 acetyl-coa carboxylase/pyruvate carboxylase 1578411 2772827 LIC11278 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyl-coa carboxylase/pyruvate carboxylase YP_001246.1 1577911 D 267671 CDS YP_001247.1 45657161 2769955 1578412..1578609 1 NC_005823.1 hypothetical protein 1578609 2769955 LIC11279 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001247.1 1578412 D 267671 CDS YP_001248.1 45657162 2771452 1579160..1580872 1 NC_005823.1 RF-3; peptide chain release factor 3 1580872 prfC 2771452 prfC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peptide chain release factor 3 YP_001248.1 1579160 D 267671 CDS YP_001249.1 45657163 2772854 1582046..1582423 1 NC_005823.1 hypothetical protein 1582423 2772854 LIC11281 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001249.1 1582046 D 267671 CDS YP_001250.1 45657164 2769759 1582600..1583118 1 NC_005823.1 hypothetical protein 1583118 2769759 LIC11282 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001250.1 1582600 D 267671 CDS YP_001251.1 45657165 2772113 complement(1583910..1584329) 1 NC_005823.1 hypothetical protein 1584329 2772113 LIC11283 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001251.1 1583910 R 267671 CDS YP_001252.1 45657166 2770520 complement(1584662..1585024) 1 NC_005823.1 hypothetical protein 1585024 2770520 LIC11284 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001252.1 1584662 R 267671 CDS YP_001253.1 45657167 2770729 1585013..1585960 1 NC_005823.1 hypothetical protein 1585960 2770729 LIC11285 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001253.1 1585013 D 267671 CDS YP_001254.1 45657168 2769689 complement(1586398..1586667) 1 NC_005823.1 hypothetical protein 1586667 2769689 LIC11286 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001254.1 1586398 R 267671 CDS YP_001255.1 45657169 2769521 1587923..1588345 1 NC_005823.1 hypothetical protein 1588345 2769521 LIC11288 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001255.1 1587923 D 267671 CDS YP_001256.1 45657170 2769482 1589281..1591587 1 NC_005823.1 hypothetical protein 1591587 2769482 LIC11289 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001256.1 1589281 D 267671 CDS YP_001257.1 45657171 2769499 1591584..1592729 1 NC_005823.1 hypothetical protein 1592729 2769499 LIC11290 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001257.1 1591584 D 267671 CDS YP_001258.1 45657172 2771022 1593266..1594375 1 NC_005823.1 histidine kinase sensor protein 1594375 2771022 LIC11291 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_001258.1 1593266 D 267671 CDS YP_001259.1 45657173 2771650 1596373..1596822 1 NC_005823.1 hypothetical protein 1596822 2771650 LIC11293 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001259.1 1596373 D 267671 CDS YP_001260.1 45657174 2771280 complement(1597982..1600081) 1 NC_005823.1 hypothetical protein 1600081 2771280 LIC11294 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001260.1 1597982 R 267671 CDS YP_001261.1 45657175 2769647 1600588..1602522 1 NC_005823.1 hypothetical protein 1602522 2769647 LIC11295 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001261.1 1600588 D 267671 CDS YP_001262.2 304570491 2769754 1602751..1603806 1 NC_005823.1 dolichyl-phosphate mannose synthase 1603806 dpm 2769754 dpm Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dolichyl-phosphate mannose synthase YP_001262.2 1602751 D 267671 CDS YP_001263.1 45657177 2770820 1604098..1604478 1 NC_005823.1 cyclopropane-fatty-acyl-phospholipid synthase/methyltransferase 1604478 2770820 LIC11297 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cyclopropane-fatty-acyl-phospholipid synthase/methyltransferase YP_001263.1 1604098 D 267671 CDS YP_001264.1 45657178 2772055 1605283..1606386 1 NC_005823.1 hypothetical protein 1606386 2772055 LIC11298 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001264.1 1605283 D 267671 CDS YP_001265.1 45657179 2771348 1607214..1607618 1 NC_005823.1 lipoprotein 1607618 2771348 LIC11299 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001265.1 1607214 D 267671 CDS YP_001266.1 45657180 2772179 complement(1607602..1608831) 1 NC_005823.1 GGDEF family protein 1608831 2772179 LIC11300 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GGDEF family protein YP_001266.1 1607602 R 267671 CDS YP_001267.1 45657181 2772617 complement(1608945..1609754) 1 NC_005823.1 hypothetical protein 1609754 2772617 LIC11301 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001267.1 1608945 R 267671 CDS YP_001268.1 45657182 2772325 complement(1609798..1610472) 1 NC_005823.1 phosphoglycolate phosphatase 1610472 gph 2772325 gph Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoglycolate phosphatase YP_001268.1 1609798 R 267671 CDS YP_001269.1 45657183 2771699 1610517..1611806 1 NC_005823.1 L-lysine 2,3-aminomutase 1611806 2771699 LIC11303 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 L-lysine 2,3-aminomutase YP_001269.1 1610517 D 267671 CDS YP_001270.1 45657184 2770442 1611799..1612923 1 NC_005823.1 d-alanine--d-alanine ligase 1612923 ddl 2770442 ddl Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 d-alanine--d-alanine ligase YP_001270.1 1611799 D 267671 CDS YP_001271.1 45657185 2770241 1612936..1613622 1 NC_005823.1 hypothetical protein 1613622 2770241 LIC11305 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001271.1 1612936 D 267671 CDS YP_001272.1 45657186 2771190 complement(1613599..1613943) 1 NC_005823.1 hypothetical protein 1613943 2771190 LIC11306 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001272.1 1613599 R 267671 CDS YP_001273.1 45657187 2772615 1614917..1615321 1 NC_005823.1 hypothetical protein 1615321 2772615 LIC11307 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001273.1 1614917 D 267671 CDS YP_001274.1 45657188 2772743 complement(1615359..1616471) 1 NC_005823.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 1616471 2772743 LIC11308 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetylglutamate kinase YP_001274.1 1615359 R 267671 CDS YP_001275.1 45657189 2771966 complement(1616487..1617737) 1 NC_005823.1 hypothetical protein 1617737 2771966 LIC11309 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001275.1 1616487 R 267671 CDS YP_001276.1 45657190 2772319 complement(1617734..1618270) 1 NC_005823.1 bacterioferritin 1618270 bfr 2772319 bfr Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 bacterioferritin YP_001276.1 1617734 R 267671 CDS YP_001277.1 45657191 2771743 1618309..1619466 1 NC_005823.1 acetyl-CoA C-acyltransferase 1619466 erg10 2771743 erg10 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyl-CoA C-acyltransferase YP_001277.1 1618309 D 267671 CDS YP_001278.1 45657192 2771074 1619480..1620511 1 NC_005823.1 lipopolysaccharide heptosyltransferase II 1620511 rfaC2 2771074 rfaC2 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipopolysaccharide heptosyltransferase II YP_001278.1 1619480 D 267671 CDS YP_001279.1 45657193 2772686 1620508..1621797 1 NC_005823.1 aminopeptidase P 1621797 pepP 2772686 pepP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aminopeptidase P YP_001279.1 1620508 D 267671 CDS YP_001280.1 45657194 2772009 1622149..1622712 1 NC_005823.1 hypothetical protein 1622712 2772009 LIC11314 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001280.1 1622149 D 267671 CDS YP_001281.1 45657195 2772657 complement(1623242..1623493) 1 NC_005823.1 hypothetical protein 1623493 2772657 LIC11315 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001281.1 1623242 R 267671 CDS YP_001282.1 45657196 2772731 1623615..1623974 1 NC_005823.1 hypothetical protein 1623974 2772731 LIC11316 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001282.1 1623615 D 267671 CDS YP_001283.1 45657197 2771432 1624216..1626504 1 NC_005823.1 hypothetical protein 1626504 2771432 LIC11317 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001283.1 1624216 D 267671 CDS YP_001284.1 45657198 2771892 complement(1627295..1628476) 1 NC_005823.1 N-acyl-L-amino acid amidohydrolase 1628476 amaA 2771892 amaA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 N-acyl-L-amino acid amidohydrolase YP_001284.1 1627295 R 267671 CDS YP_001285.1 45657199 2772716 1629285..1629479 1 NC_005823.1 hypothetical protein 1629479 2772716 LIC11319 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001285.1 1629285 D 267671 CDS YP_001286.1 45657200 2772139 complement(1629596..1630612) 1 NC_005823.1 hypothetical protein 1630612 2772139 LIC11320 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001286.1 1629596 R 267671 CDS YP_001287.1 45657201 2770347 1631184..1631450 1 NC_005823.1 hypothetical protein 1631450 2770347 LIC11321 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001287.1 1631184 D 267671 CDS YP_001288.1 45657202 2771774 complement(1632269..1632460) 1 NC_005823.1 hypothetical protein 1632460 2771774 LIC11322 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001288.1 1632269 R 267671 CDS YP_001289.1 45657203 2772076 1632977..1634128 1 NC_005823.1 methyltransferase DNA modification enzyme 1634128 2772076 LIC11323 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methyltransferase DNA modification enzyme YP_001289.1 1632977 D 267671 CDS YP_001290.1 45657204 2771422 1635268..1636065 1 NC_005823.1 distal rod protein; makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1636065 flgG 2771422 flgG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar basal body rod protein FlgG YP_001290.1 1635268 D 267671 CDS YP_001291.1 45657205 2772032 1636084..1636974 1 NC_005823.1 flagella basal body P-ring formation protein precursor 1636974 flgA 2772032 flgA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagella basal body P-ring formation protein precursor YP_001291.1 1636084 D 267671 CDS YP_001292.1 45657206 2772447 1636971..1637972 1 NC_005823.1 flagellar L-ring protein precursor 1637972 flgH 2772447 flgH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar L-ring protein precursor YP_001292.1 1636971 D 267671 CDS YP_001293.1 45657207 2772225 1637969..1639069 1 NC_005823.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1639069 flgI 2772225 flgI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar basal body P-ring protein YP_001293.1 1637969 D 267671 CDS YP_001294.1 45657208 2770218 1639066..1639539 1 NC_005823.1 flagellum-specific muramidase 1639539 flgJ 2770218 flgJ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellum-specific muramidase YP_001294.1 1639066 D 267671 CDS YP_001295.1 45657209 2772531 complement(1640135..1642384) 1 NC_005823.1 ribonuclease BN transmembrane protein 1642384 2772531 LIC11329 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribonuclease BN transmembrane protein YP_001295.1 1640135 R 267671 CDS YP_001296.1 45657210 2771625 complement(1643876..1645144) 1 NC_005823.1 hypothetical protein 1645144 2771625 LIC11332 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001296.1 1643876 R 267671 CDS YP_001297.1 45657211 2771315 1645307..1645531 1 NC_005823.1 hypothetical protein 1645531 2771315 LIC11333 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001297.1 1645307 D 267671 CDS YP_001298.1 45657212 2772372 complement(1646210..1646881) 1 NC_005823.1 hypothetical protein 1646881 2772372 LIC11334 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001298.1 1646210 R 267671 CDS YP_001299.1 45657213 2772340 complement(1646985..1648625) 1 NC_005823.1 chaperonin; 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 1648625 groEL 2772340 groEL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chaperonin GroEL YP_001299.1 1646985 R 267671 CDS YP_001300.1 45657214 2770194 complement(1648640..1648930) 1 NC_005823.1 heat shock protein; 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 1648930 groES 2770194 groES Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 co-chaperonin GroES YP_001300.1 1648640 R 267671 CDS YP_001301.1 45657215 2772279 complement(1649307..1649513) 1 NC_005823.1 hypothetical protein 1649513 2772279 LIC11337 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001301.1 1649307 R 267671 CDS YP_001302.1 45657216 2770568 complement(1650635..1651045) 1 NC_005823.1 hypothetical protein 1651045 2770568 LIC11338 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001302.1 1650635 R 267671 CDS YP_001303.1 45657217 2772713 1651973..1653523 1 NC_005823.1 deoxyribodipyrimidine photolyase 1653523 phr 2772713 phr Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 deoxyribodipyrimidine photolyase YP_001303.1 1651973 D 267671 CDS YP_001304.1 45657218 2770339 1653813..1654157 1 NC_005823.1 hypothetical protein 1654157 2770339 LIC11340 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001304.1 1653813 D 267671 CDS YP_001305.1 45657219 2772762 1654489..1654719 1 NC_005823.1 hypothetical protein 1654719 2772762 LIC11341 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001305.1 1654489 D 267671 CDS YP_001306.1 45657220 2771169 1654955..1655437 1 NC_005823.1 hypothetical protein 1655437 2771169 LIC11342 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001306.1 1654955 D 267671 CDS YP_001307.1 45657221 2771562 complement(1655628..1656965) 1 NC_005823.1 adenylate/guanylate cyclase 1656965 2771562 LIC11343 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_001307.1 1655628 R 267671 CDS YP_001308.1 45657222 2772789 1657098..1657766 1 NC_005823.1 hypothetical protein 1657766 2772789 LIC11344 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001308.1 1657098 D 267671 CDS YP_001309.1 45657223 2772155 complement(1658322..1660562) 1 NC_005823.1 ferrichrome-iron receptor 1660562 2772155 LIC11345 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ferrichrome-iron receptor YP_001309.1 1658322 R 267671 CDS YP_001310.1 45657224 2771341 complement(1661149..1661775) 1 NC_005823.1 transposase, IS1501 1661775 2771341 LIC11346 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, IS1501 YP_001310.1 1661149 R 267671 CDS YP_001311.1 45657225 2771343 complement(1661993..1662298) 1 NC_005823.1 transposase, IS1501 1662298 2771343 LIC11347 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, IS1501 YP_001311.1 1661993 R 267671 CDS YP_001312.1 45657226 2772777 complement(1662530..1662826) 1 NC_005823.1 hypothetical protein 1662826 2772777 LIC11348 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001312.1 1662530 R 267671 CDS YP_001313.1 45657227 2770500 complement(1662904..1663194) 1 NC_005823.1 hypothetical protein 1663194 2770500 LIC11349 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001313.1 1662904 R 267671 CDS YP_001314.1 45657228 2772574 complement(1663262..1665022) 1 NC_005823.1 acyl-CoA dehydrogenase 1665022 2772574 LIC11350 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyl-CoA dehydrogenase YP_001314.1 1663262 R 267671 CDS YP_001315.1 45657229 2771036 1665692..1665889 1 NC_005823.1 hypothetical protein 1665889 2771036 LIC11351 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001315.1 1665692 D 267671 CDS YP_001316.1 45657230 2772192 complement(1666299..1667117) 1 NC_005823.1 lipoprotein; major outer membrance protein; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 1667117 lipL32 2772192 lipL32 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001316.1 1666299 R 267671 CDS YP_001317.1 45657231 2771704 complement(1667349..1667747) 1 NC_005823.1 ParB family protein 1667747 2771704 LIC11353 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ParB family protein YP_001317.1 1667349 R 267671 CDS YP_001318.2 161621776 2770361 1667918..1669078 1 NC_005823.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1669078 metK 2770361 metK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 S-adenosylmethionine synthetase YP_001318.2 1667918 D 267671 CDS YP_001319.1 45657233 2769816 1669086..1670048 1 NC_005823.1 transketolase 1670048 tkt 2769816 tkt Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transketolase YP_001319.1 1669086 D 267671 CDS YP_001320.1 45657234 2771831 1670167..1670487 1 NC_005823.1 hypothetical protein 1670487 2771831 LIC11356 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001320.1 1670167 D 267671 CDS YP_001321.1 45657235 2771407 complement(1671042..1672070) 1 NC_005823.1 alcohol dehydrogenase 1672070 2771407 LIC11357 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alcohol dehydrogenase YP_001321.1 1671042 R 267671 CDS YP_001322.1 45657236 2772665 1672320..1674236 1 NC_005823.1 hypothetical protein 1674236 2772665 LIC11358 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001322.1 1672320 D 267671 CDS YP_001323.1 45657237 2771730 complement(1674377..1675555) 1 NC_005823.1 hypothetical protein 1675555 maoC 2771730 maoC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001323.1 1674377 R 267671 CDS YP_001324.1 45657238 2772884 complement(1675783..1676421) 1 NC_005823.1 lipoprotein 1676421 2772884 LIC11360 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001324.1 1675783 R 267671 CDS YP_001325.1 45657239 2772940 1677240..1679195 1 NC_005823.1 oligopeptidase A 1679195 prlC 2772940 prlC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 oligopeptidase A YP_001325.1 1677240 D 267671 CDS YP_001326.1 45657240 2769630 complement(1679203..1679448) 1 NC_005823.1 hypothetical protein 1679448 2769630 LIC11362 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001326.1 1679203 R 267671 CDS YP_001327.1 45657241 2769805 complement(1679513..1680169) 1 NC_005823.1 glutathione-S-transferase 1680169 2769805 LIC11363 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutathione-S-transferase YP_001327.1 1679513 R 267671 CDS YP_001328.1 45657242 2769946 1680356..1681141 1 NC_005823.1 short-chain dehydrogenase 1681141 dltE 2769946 dltE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 short-chain dehydrogenase YP_001328.1 1680356 D 267671 CDS YP_001329.1 45657243 2769559 1681148..1682344 1 NC_005823.1 C-5 sterol desaturase 1682344 erg3 2769559 erg3 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 C-5 sterol desaturase YP_001329.1 1681148 D 267671 CDS YP_001330.1 45657244 2772931 complement(1682693..1683559) 1 NC_005823.1 hypothetical protein 1683559 2772931 LIC11366 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001330.1 1682693 R 267671 CDS YP_001331.1 45657245 2772944 1683543..1683737 1 NC_005823.1 hypothetical protein 1683737 2772944 LIC11367 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001331.1 1683543 D 267671 CDS YP_001332.1 45657246 2772917 1683706..1685847 1 NC_005823.1 sodium/alanine symporter family protein 1685847 2772917 LIC11368 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sodium/alanine symporter family protein YP_001332.1 1683706 D 267671 CDS YP_001333.1 45657247 2772891 1686210..1686536 1 NC_005823.1 hypothetical protein 1686536 2772891 LIC11369 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001333.1 1686210 D 267671 CDS YP_001334.1 45657248 2770348 1687104..1688168 1 NC_005823.1 flagellar motor switch protein 1688168 fliN 2770348 fliN Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar motor switch protein YP_001334.1 1687104 D 267671 CDS YP_001335.1 45657249 2770448 1688165..1688986 1 NC_005823.1 hypothetical protein 1688986 fliO 2770448 fliO Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001335.1 1688165 D 267671 CDS YP_001336.1 45657250 2771739 1689019..1689822 1 NC_005823.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 1689822 fliP 2771739 fliP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar biosynthesis protein FliP YP_001336.1 1689019 D 267671 CDS YP_001337.1 45657251 2772870 1689819..1690082 1 NC_005823.1 flagellar biosynthetic protein fliQ 1690082 fliQ 2772870 fliQ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar biosynthetic protein fliQ YP_001337.1 1689819 D 267671 CDS YP_001338.1 45657252 2772853 1690089..1690868 1 NC_005823.1 flagellar biosynthetic protein 1690868 fliR 2772853 fliR Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar biosynthetic protein YP_001338.1 1690089 D 267671 CDS YP_001339.1 45657253 2770446 1690856..1692805 1 NC_005823.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 1692805 flhB 2770446 flhB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar biosynthesis protein FlhB YP_001339.1 1690856 D 267671 CDS YP_001340.1 45657254 2770201 1692815..1694932 1 NC_005823.1 flagellar biosynthesis transmembrane protein 1694932 flhA 2770201 flhA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar biosynthesis transmembrane protein YP_001340.1 1692815 D 267671 CDS YP_001341.1 45657255 2770079 1694979..1696265 1 NC_005823.1 Positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF 1696265 flhF 2770079 flhF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar biosynthesis regulator FlhF YP_001341.1 1694979 D 267671 CDS YP_001342.1 45657256 2770082 1696293..1697207 1 NC_005823.1 MinD; septum site-determining protein 1697207 minD 2770082 minD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 septum site-determining protein YP_001342.1 1696293 D 267671 CDS YP_001343.1 45657257 2772602 1697211..1697687 1 NC_005823.1 hypothetical protein 1697687 2772602 LIC11379 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001343.1 1697211 D 267671 CDS YP_001344.1 45657258 2770243 1697815..1698615 1 NC_005823.1 involved in the initiation of sporulation and glycogen biosynthesis; RNA polymerase sigma factor WhiG 1698615 2770243 LIC11380 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA polymerase sigma factor WhiG YP_001344.1 1697815 D 267671 CDS YP_001345.1 45657259 2771144 1698641..1700626 1 NC_005823.1 hypothetical protein 1700626 2771144 LIC11381 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001345.1 1698641 D 267671 CDS YP_001346.1 45657260 2769795 1700635..1700988 1 NC_005823.1 hypothetical protein 1700988 2769795 LIC11382 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001346.1 1700635 D 267671 CDS YP_001347.1 45657261 2772673 1701004..1702086 1 NC_005823.1 hypothetical protein 1702086 2772673 LIC11383 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001347.1 1701004 D 267671 CDS YP_001348.1 45657262 2772483 1702086..1702367 1 NC_005823.1 hypothetical protein 1702367 2772483 LIC11384 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001348.1 1702086 D 267671 CDS YP_001349.1 45657263 2772759 complement(1703845..1704039) 1 NC_005823.1 hypothetical protein 1704039 2772759 LIC11386 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001349.1 1703845 R 267671 CDS YP_001350.1 45657264 2770069 complement(1704590..1705183) 1 NC_005823.1 hypothetical protein 1705183 2770069 LIC11387 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001350.1 1704590 R 267671 CDS YP_001351.1 45657265 2772145 complement(1705231..1705623) 1 NC_005823.1 hypothetical protein 1705623 2772145 LIC11388 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001351.1 1705231 R 267671 CDS YP_001352.1 45657266 2771815 complement(1705636..1706283) 1 NC_005823.1 flagellar protein B 1706283 flbB 2771815 flbB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar protein B YP_001352.1 1705636 R 267671 CDS YP_001353.1 45657267 2771687 complement(1706442..1707008) 1 NC_005823.1 flagellar protein; hypothetical protein 1707008 fliJ 2771687 fliJ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001353.1 1706442 R 267671 CDS YP_001354.1 45657268 2771467 complement(1707012..1708376) 1 NC_005823.1 type III secretory pathway ATPase; hypothetical protein 1708376 fliI 2771467 fliI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001354.1 1707012 R 267671 CDS YP_001355.1 45657269 2772782 1709642..1711342 1 NC_005823.1 flagellar protein; the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 1711342 fliF 2772782 fliF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar MS-ring protein YP_001355.1 1709642 D 267671 CDS YP_001356.1 45657270 2772640 1711339..1712310 1 NC_005823.1 hypothetical protein 1712310 2772640 LIC11393 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001356.1 1711339 D 267671 CDS YP_001357.1 45657271 2772549 1712314..1713237 1 NC_005823.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 1713237 fliH 2772549 fliH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar assembly protein H YP_001357.1 1712314 D 267671 CDS YP_001358.1 45657272 2770234 1713244..1713606 1 NC_005823.1 hypothetical protein 1713606 2770234 LIC11395 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001358.1 1713244 D 267671 CDS YP_001359.1 45657273 2772380 complement(1714747..1715667) 1 NC_005823.1 hypothetical protein 1715667 2772380 LIC11396 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001359.1 1714747 R 267671 CDS YP_001360.1 45657274 2772729 complement(1715977..1716528) 1 NC_005823.1 hypothetical protein 1716528 2772729 LIC11397 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001360.1 1715977 R 267671 CDS YP_001361.1 45657275 2769824 1717087..1718148 1 NC_005823.1 hypothetical protein 1718148 2769824 LIC11398 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001361.1 1717087 D 267671 CDS YP_001362.1 45657276 2772250 complement(1718592..1719734) 1 NC_005823.1 membrane metalloendopeptidase 1719734 2772250 LIC11399 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 membrane metalloendopeptidase YP_001362.1 1718592 R 267671 CDS YP_001363.1 45657277 2769915 complement(1719727..1720725) 1 NC_005823.1 N-acetylneuraminate synthase 1720725 2769915 LIC11400 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 N-acetylneuraminate synthase YP_001363.1 1719727 R 267671 CDS YP_001364.1 45657278 2771741 complement(1720741..1722726) 1 NC_005823.1 phosphoglycerol transferase related protein 1722726 2771741 LIC11401 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoglycerol transferase related protein YP_001364.1 1720741 R 267671 CDS YP_001365.1 45657279 2771764 complement(1722708..1724813) 1 NC_005823.1 ferrous iron transport protein b 1724813 feoB 2771764 feoB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ferrous iron transport protein b YP_001365.1 1722708 R 267671 CDS YP_001366.1 45657280 2769874 complement(1724800..1725045) 1 NC_005823.1 hypothetical protein 1725045 2769874 LIC11403 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001366.1 1724800 R 267671 CDS YP_001367.1 45657281 2771794 complement(1725042..1726370) 1 NC_005823.1 ubiquinone biosynthesis protein 1726370 ubiB 2771794 ubiB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ubiquinone biosynthesis protein YP_001367.1 1725042 R 267671 CDS YP_001368.1 45657282 2770242 1726506..1728509 1 NC_005823.1 hypothetical protein 1728509 2770242 LIC11405 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001368.1 1726506 D 267671 CDS YP_001369.1 45657283 2770228 complement(1728850..1729119) 1 NC_005823.1 hypothetical protein 1729119 2770228 LIC11406 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001369.1 1728850 R 267671 CDS YP_001370.1 45657284 2772318 complement(1729200..1731740) 1 NC_005823.1 methyl-accepting chemotaxis transmembrane protein 1731740 2772318 LIC11407 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methyl-accepting chemotaxis transmembrane protein YP_001370.1 1729200 R 267671 CDS YP_001371.1 45657285 2772471 complement(1732303..1733412) 1 NC_005823.1 internal repeat sequences detected; contains TPR domain as detected by pfam-hmmr; hypothetical protein 1733412 2772471 LIC11408 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001371.1 1732303 R 267671 CDS YP_001372.1 45657286 2770437 1733773..1735551 1 NC_005823.1 acetolactate synthase large subunit 1735551 2770437 LIC11409 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetolactate synthase large subunit YP_001372.1 1733773 D 267671 CDS YP_001373.1 45657287 2771868 1735548..1736033 1 NC_005823.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1736033 ilvH 2771868 ilvH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetolactate synthase 3 regulatory subunit YP_001373.1 1735548 D 267671 CDS YP_001374.1 45657288 2771692 complement(1737172..1737579) 1 NC_005823.1 hypothetical protein 1737579 2771692 LIC11411 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001374.1 1737172 R 267671 CDS YP_001375.1 45657289 2772234 complement(1738228..1739394) 1 NC_005823.1 coproporphyrinogen III oxidase 1739394 2772234 LIC11412 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 coproporphyrinogen III oxidase YP_001375.1 1738228 R 267671 CDS YP_001376.1 45657290 2770265 complement(1739391..1741208) 1 NC_005823.1 glycosyl hydrolase 1741208 2770265 LIC11413 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyl hydrolase YP_001376.1 1739391 R 267671 CDS YP_001377.1 45657291 2771159 1741195..1741827 1 NC_005823.1 acyl-CoA thioesterase 1741827 tesA 2771159 tesA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyl-CoA thioesterase YP_001377.1 1741195 D 267671 CDS YP_001378.1 45657292 2772717 1741996..1743351 1 NC_005823.1 trigger factor; FKBP-type peptidyl-prolyl cis-trans isomerase 1743351 tig 2772717 tig Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 FKBP-type peptidyl-prolyl cis-trans isomerase YP_001378.1 1741996 D 267671 CDS YP_001379.1 45657293 2770815 1743348..1743944 1 NC_005823.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1743944 clpP 2770815 clpP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent Clp protease proteolytic subunit YP_001379.1 1743348 D 267671 CDS YP_001380.1 45657294 2772828 1743955..1745217 1 NC_005823.1 ATP-binding specificity subunit; binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1745217 clpX 2772828 clpX Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent protease ATP-binding subunit ClpX YP_001380.1 1743955 D 267671 CDS YP_001381.1 45657295 2771246 complement(1745229..1745714) 1 NC_005823.1 hypothetical protein 1745714 2771246 LIC11419 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001381.1 1745229 R 267671 CDS YP_001382.1 45657296 2771756 complement(1745801..1746289) 1 NC_005823.1 GNAT family acetyltransferase 1746289 2771756 LIC11420 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GNAT family acetyltransferase YP_001382.1 1745801 R 267671 CDS YP_001383.1 45657297 2772821 complement(1746773..1749064) 1 NC_005823.1 phosphate sodium symporter 1749064 2772821 LIC11421 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphate sodium symporter YP_001383.1 1746773 R 267671 CDS YP_001384.1 45657298 2770221 complement(1749349..1750395) 1 NC_005823.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 1750395 2770221 LIC11422 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 serine/threonine protein kinase YP_001384.1 1749349 R 267671 CDS YP_001385.1 45657299 2772848 1750506..1750901 1 NC_005823.1 glycine rich RNA-binding protein 1750901 2772848 LIC11423 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycine rich RNA-binding protein YP_001385.1 1750506 D 267671 CDS YP_001386.1 45657300 2771854 1750898..1751287 1 NC_005823.1 peptidyl-prolyl cis-trans isomerase 1751287 fkp 2771854 fkp Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peptidyl-prolyl cis-trans isomerase YP_001386.1 1750898 D 267671 CDS YP_001387.1 45657301 2770481 1751396..1752517 1 NC_005823.1 histidine kinase sensor protein 1752517 2770481 LIC11425 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_001387.1 1751396 D 267671 CDS YP_001388.1 45657302 2771662 1752578..1753834 1 NC_005823.1 sigma factor regulatory protein 1753834 2771662 LIC11426 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sigma factor regulatory protein YP_001388.1 1752578 D 267671 CDS YP_001389.1 45657303 2772317 1753836..1755059 1 NC_005823.1 capsule biosynthesis protein 1755059 capB 2772317 capB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 capsule biosynthesis protein YP_001389.1 1753836 D 267671 CDS YP_001390.1 45657304 2771204 1755100..1755507 1 NC_005823.1 capsule biosynthesis protein 1755507 capC 2771204 capC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 capsule biosynthesis protein YP_001390.1 1755100 D 267671 CDS YP_001391.1 45657305 2772674 1755504..1756601 1 NC_005823.1 hypothetical protein 1756601 2772674 LIC11429 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001391.1 1755504 D 267671 CDS YP_001392.1 45657306 2771173 complement(1756884..1757873) 1 NC_005823.1 alpha/beta fold family hydrolase 1757873 2771173 LIC11430 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alpha/beta fold family hydrolase YP_001392.1 1756884 R 267671 CDS YP_001393.1 45657307 2770053 1758452..1758928 1 NC_005823.1 cyclic nucleotide binding protein 1758928 2770053 LIC11431 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cyclic nucleotide binding protein YP_001393.1 1758452 D 267671 CDS YP_001394.1 45657308 2771767 complement(1759004..1762057) 1 NC_005823.1 histidine kinase response regulator hybrid protein 1762057 2771767 LIC11432 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase response regulator hybrid protein YP_001394.1 1759004 R 267671 CDS YP_001395.1 45657309 2771907 1762262..1763731 1 NC_005823.1 histidine kinase sensor protein 1763731 2771907 LIC11433 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_001395.1 1762262 D 267671 CDS YP_001396.1 45657310 2771308 1763774..1765645 1 NC_005823.1 ABC transporter ATP-binding protein 1765645 2771308 LIC11434 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_001396.1 1763774 D 267671 CDS YP_001397.1 45657311 2772515 complement(1766290..1767414) 1 NC_005823.1 hypothetical protein 1767414 2772515 LIC11435 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001397.1 1766290 R 267671 CDS YP_001398.1 45657312 2770212 complement(1767404..1769521) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 1769521 2770212 LIC11436 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001398.1 1767404 R 267671 CDS YP_001399.1 45657313 2771084 complement(1769505..1772387) 1 NC_005823.1 adenylate/guanylate cyclase 1772387 2771084 LIC11437 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_001399.1 1769505 R 267671 CDS YP_001400.1 45657314 2772556 1772588..1773046 1 NC_005823.1 peptidyl-prolyl cis-trans isomerase 1773046 ppi 2772556 ppi Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peptidyl-prolyl cis-trans isomerase YP_001400.1 1772588 D 267671 CDS YP_001401.1 45657315 2769869 1774839..1775876 1 NC_005823.1 histidine kinase sensor protein 1775876 2769869 LIC11439 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_001401.1 1774839 D 267671 CDS YP_001402.1 45657316 2771773 1775899..1777350 1 NC_005823.1 histidine kinase response regulator hybrid protein 1777350 2771773 LIC11440 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase response regulator hybrid protein YP_001402.1 1775899 D 267671 CDS YP_001403.1 45657317 2772116 complement(1778576..1779052) 1 NC_005823.1 hypothetical protein 1779052 2772116 LIC11441 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001403.1 1778576 R 267671 CDS YP_001404.1 45657318 2771395 complement(1779022..1779480) 1 NC_005823.1 hypothetical protein 1779480 2771395 LIC11442 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001404.1 1779022 R 267671 CDS YP_001405.1 45657319 2771647 complement(1779533..1779919) 1 NC_005823.1 outer membrane protein 1779919 2771647 LIC11443 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 outer membrane protein YP_001405.1 1779533 R 267671 CDS YP_001406.1 45657320 2770476 1780063..1781055 1 NC_005823.1 response regulator 1781055 2770476 LIC11444 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_001406.1 1780063 D 267671 CDS YP_001407.1 45657321 2769806 complement(1781344..1782687) 1 NC_005823.1 hydroxypyruvate reductase 1782687 2769806 LIC11445 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hydroxypyruvate reductase YP_001407.1 1781344 R 267671 CDS YP_001408.1 45657322 2771657 1783392..1784282 1 NC_005823.1 alpha/beta hydrolase fold family; identified by sequence similarity; ORF located using Blastx/Glimmer; hydrolase 1784282 2771657 LIC11446 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hydrolase YP_001408.1 1783392 D 267671 CDS YP_001409.1 45657323 2772214 1785817..1786320 1 NC_005823.1 hypothetical protein 1786320 2772214 LIC11447 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001409.1 1785817 D 267671 CDS YP_001410.1 45657324 2770445 complement(1786765..1787145) 1 NC_005823.1 transposase, ISlin1 1787145 2770445 LIC11448 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_001410.1 1786765 R 267671 CDS YP_001411.1 45657325 2771890 complement(1787130..1787717) 1 NC_005823.1 transposase, ISlin1 1787717 2771890 LIC11449 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_001411.1 1787130 R 267671 CDS YP_001412.1 45657326 2771787 complement(1787773..1788018) 1 NC_005823.1 transposase, ISlin1 1788018 2771787 LIC11450 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_001412.1 1787773 R 267671 CDS YP_001413.1 45657327 2770605 complement(1789376..1790140) 1 NC_005823.1 exodeoxyribonuclease 1790140 2770605 LIC11452 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 exodeoxyribonuclease YP_001413.1 1789376 R 267671 CDS YP_001414.1 45657328 2772163 1790240..1791523 1 NC_005823.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 1791523 hisD 2772163 hisD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidinol dehydrogenase YP_001414.1 1790240 D 267671 CDS YP_001415.1 45657329 2769926 1791554..1792411 1 NC_005823.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 1792411 panC 2769926 panC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pantoate--beta-alanine ligase YP_001415.1 1791554 D 267671 CDS YP_001416.1 45657330 2772587 1792408..1795968 1 NC_005823.1 transcription-repair coupling factor 1795968 mfd 2772587 mfd Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transcription-repair coupling factor YP_001416.1 1792408 D 267671 CDS YP_001417.1 45657331 2771780 1796015..1796740 1 NC_005823.1 inner membrance lipoprotein; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 1796740 lipL31 2771780 lipL31 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001417.1 1796015 D 267671 CDS YP_001418.1 45657332 2771065 1796747..1797580 1 NC_005823.1 bacitracin resistance protein 1797580 bacA 2771065 bacA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 bacitracin resistance protein YP_001418.1 1796747 D 267671 CDS YP_001419.1 45657333 2772625 1797604..1800579 1 NC_005823.1 porin superfamily outer membrane protein 1800579 2772625 LIC11458 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 porin superfamily outer membrane protein YP_001419.1 1797604 D 267671 CDS YP_001420.1 45657334 2771952 1800576..1801997 1 NC_005823.1 UDP-glucosyltransferase 1801997 wcaJ 2771952 wcaJ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-glucosyltransferase YP_001420.1 1800576 D 267671 CDS YP_001421.1 45657335 2772373 1802024..1802314 1 NC_005823.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1802314 gatC 2772373 gatC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_001421.1 1802024 D 267671 CDS YP_001422.1 45657336 2771369 1802311..1803774 1 NC_005823.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1803774 gatA 2771369 gatA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_001422.1 1802311 D 267671 CDS YP_001423.1 45657337 2771399 1803771..1804541 1 NC_005823.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 1804541 hisF 2771399 hisF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 imidazole glycerol phosphate synthase subunit HisF YP_001423.1 1803771 D 267671 CDS YP_001424.1 45657338 2771300 complement(1805167..1806276) 1 NC_005823.1 hypothetical protein 1806276 2771300 LIC11463 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001424.1 1805167 R 267671 CDS YP_001425.1 45657339 2772772 1807019..1807210 1 NC_005823.1 hypothetical protein 1807210 2772772 LIC11464 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001425.1 1807019 D 267671 CDS YP_001426.1 45657340 2771460 complement(1807593..1808486) 1 NC_005823.1 hypothetical protein 1808486 2771460 LIC11465 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001426.1 1807593 R 267671 CDS YP_001427.1 45657341 2770928 complement(1810131..1811633) 1 NC_005823.1 hypothetical protein 1811633 2770928 LIC11466 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001427.1 1810131 R 267671 CDS YP_001428.1 45657342 2771106 complement(1811649..1813145) 1 NC_005823.1 RCC1; regulator of chromosome condensation 1813145 2771106 LIC11467 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 regulator of chromosome condensation YP_001428.1 1811649 R 267671 CDS YP_001429.1 45657343 2770323 1813313..1814782 1 NC_005823.1 hypothetical protein 1814782 2770323 LIC11468 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001429.1 1813313 D 267671 CDS YP_001430.1 45657344 2772019 1814833..1815426 1 NC_005823.1 hypothetical protein 1815426 2772019 LIC11469 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001430.1 1814833 D 267671 CDS YP_001431.1 45657345 2772818 complement(1817325..1818275) 1 NC_005823.1 thioredoxin reductase 1818275 trxB 2772818 trxB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thioredoxin reductase YP_001431.1 1817325 R 267671 CDS YP_001432.1 45657346 2771015 complement(1819711..1820070) 1 NC_005823.1 transposase, ISlin1 1820070 2771015 LIC11471 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_001432.1 1819711 R 267671 CDS YP_001433.1 45657347 2770497 complement(1820076..1820681) 1 NC_005823.1 transposase, ISlin1 1820681 2770497 LIC11472 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_001433.1 1820076 R 267671 CDS YP_001434.1 45657348 2771150 complement(1820719..1821027) 1 NC_005823.1 transposase, ISlin1 1821027 2771150 LIC11473 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_001434.1 1820719 R 267671 CDS YP_001435.1 45657349 2772260 1821684..1823024 1 NC_005823.1 hypothetical protein 1823024 2772260 LIC11474 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001435.1 1821684 D 267671 CDS YP_001436.1 45657350 2769993 1823014..1824450 1 NC_005823.1 alginate o-acetyltransferase 1824450 2769993 LIC11475 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alginate o-acetyltransferase YP_001436.1 1823014 D 267671 CDS YP_001437.1 45657351 2771051 complement(1824497..1825036) 1 NC_005823.1 hypothetical protein 1825036 2771051 LIC11476 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001437.1 1824497 R 267671 CDS YP_001438.1 45657352 2771373 complement(1825627..1826655) 1 NC_005823.1 hypothetical protein 1826655 2771373 LIC11477 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001438.1 1825627 R 267671 CDS YP_001439.1 45657353 2771117 complement(1826786..1827661) 1 NC_005823.1 hypothetical protein 1827661 2771117 LIC11478 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001439.1 1826786 R 267671 CDS YP_001440.1 45657354 2769619 1827759..1828655 1 NC_005823.1 integrase/recombinase protein 1828655 xerD 2769619 xerD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 integrase/recombinase protein YP_001440.1 1827759 D 267671 CDS YP_001441.1 45657355 2769562 1829149..1829577 1 NC_005823.1 anti-sigma factor antagonist 1829577 2769562 LIC11480 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_001441.1 1829149 D 267671 CDS YP_001442.1 45657356 2772334 1829574..1829972 1 NC_005823.1 hypothetical protein 1829972 2772334 LIC11481 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001442.1 1829574 D 267671 CDS YP_001443.1 45657357 2771841 1830045..1830410 1 NC_005823.1 hypothetical protein 1830410 2771841 LIC11482 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001443.1 1830045 D 267671 CDS YP_001444.1 45657358 2771870 complement(1830772..1832490) 1 NC_005823.1 hypothetical protein 1832490 2771870 LIC11483 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001444.1 1830772 R 267671 CDS YP_001445.1 45657359 2769516 complement(1832834..1833529) 1 NC_005823.1 Crp family transcriptional regulator 1833529 2769516 LIC11484 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Crp family transcriptional regulator YP_001445.1 1832834 R 267671 CDS YP_001446.1 45657360 2769508 1833692..1834303 1 NC_005823.1 hypothetical protein 1834303 2769508 LIC11485 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001446.1 1833692 D 267671 CDS YP_001447.1 45657361 2769512 1834300..1835295 1 NC_005823.1 hypothetical protein 1835295 2769512 LIC11486 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001447.1 1834300 D 267671 CDS YP_001448.1 45657362 2769501 complement(1835557..1836108) 1 NC_005823.1 hypothetical protein 1836108 2769501 LIC11487 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001448.1 1835557 R 267671 CDS YP_001449.1 45657363 2772391 complement(1836551..1837015) 1 NC_005823.1 chemotaxis protein 1837015 cheX 2772391 cheX Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chemotaxis protein YP_001449.1 1836551 R 267671 CDS YP_001450.1 45657364 2769579 complement(1837015..1838349) 1 NC_005823.1 hypothetical protein 1838349 2769579 LIC11489 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001450.1 1837015 R 267671 CDS YP_001451.1 45657365 2769547 1838353..1839102 1 NC_005823.1 hypothetical protein 1839102 2769547 LIC11490 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001451.1 1838353 D 267671 CDS YP_001452.1 45657366 2769663 complement(1839796..1840548) 1 NC_005823.1 hypothetical protein 1840548 2769663 LIC11491 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001452.1 1839796 R 267671 CDS YP_001453.1 45657367 2769717 complement(1840979..1841989) 1 NC_005823.1 hypothetical protein 1841989 2769717 LIC11492 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001453.1 1840979 R 267671 CDS YP_001454.1 45657368 2769705 complement(1841986..1843692) 1 NC_005823.1 gliding motility protein; GldG 1843692 gldG 2769705 gldG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GldG YP_001454.1 1841986 R 267671 CDS YP_001455.1 45657369 2769917 complement(1843689..1844435) 1 NC_005823.1 gliding motility protein; GldF 1844435 gldF 2769917 gldF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GldF YP_001455.1 1843689 R 267671 CDS YP_001456.1 45657370 2769770 complement(1844416..1845354) 1 NC_005823.1 ABC transporter ATP-binding protein 1845354 gldA 2769770 gldA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_001456.1 1844416 R 267671 CDS YP_001457.1 45657371 2771357 complement(1845414..1845710) 1 NC_005823.1 hypothetical protein 1845710 2771357 LIC11496 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001457.1 1845414 R 267671 CDS YP_001458.1 45657372 2770090 complement(1845791..1846570) 1 NC_005823.1 methyltransferase 1846570 2770090 LIC11497 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methyltransferase YP_001458.1 1845791 R 267671 CDS YP_001459.1 45657373 2772749 1846811..1850224 1 NC_005823.1 hypothetical protein 1850224 2772749 LIC11498 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001459.1 1846811 D 267671 CDS YP_001460.1 45657374 2771539 1850464..1850706 1 NC_005823.1 hypothetical protein 1850706 2771539 LIC11499 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001460.1 1850464 D 267671 CDS YP_001461.1 45657375 2772028 1850713..1851471 1 NC_005823.1 MAP; methionine aminopeptidase 1851471 map 2772028 map Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methionine aminopeptidase YP_001461.1 1850713 D 267671 CDS YP_001462.1 45657376 2770944 1851482..1852399 1 NC_005823.1 internal repeat sequences detected; contains DUF350 domain as detected by pfam-hmmr; hypothetical protein 1852399 2770944 LIC11501 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001462.1 1851482 D 267671 CDS YP_001463.1 45657377 2771908 complement(1853404..1853844) 1 NC_005823.1 hypothetical protein 1853844 2771908 LIC11502 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001463.1 1853404 R 267671 CDS YP_001464.1 45657378 2770988 1853859..1854797 1 NC_005823.1 iron-sulfur cluster-binding protein 1854797 2770988 LIC11503 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 iron-sulfur cluster-binding protein YP_001464.1 1853859 D 267671 CDS YP_001465.1 45657379 2770024 1855127..1855927 1 NC_005823.1 contains leucine-rich repeats; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 1855927 2770024 LIC11504 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001465.1 1855127 D 267671 CDS YP_001466.1 45657380 2772700 1856137..1857855 1 NC_005823.1 internal repeat sequences detected; contains Leucine rich repeat as detected by pfam-hmmr; hypothetical protein 1857855 2772700 LIC11505 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001466.1 1856137 D 267671 CDS YP_001467.1 45657381 2771884 1858282..1859268 1 NC_005823.1 transmembrane; identified by sequence similarity; ORF located using Blastx/Glimmer; outer membrane protein 1859268 2771884 LIC11506 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 outer membrane protein YP_001467.1 1858282 D 267671 CDS YP_001468.1 45657382 2770371 1859433..1860935 1 NC_005823.1 internal repeat sequences detected; contains Leucine rich repeat as detected by pfam-hmmr; hypothetical protein 1860935 2770371 LIC11507 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001468.1 1859433 D 267671 CDS YP_001469.1 45657383 2771406 1864812..1865894 1 NC_005823.1 iron-regulated; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 1865894 2771406 LIC11509 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001469.1 1864812 D 267671 CDS YP_001470.1 45657384 2772765 complement(1865972..1869214) 1 NC_005823.1 heavy metal efflux pump 1869214 2772765 LIC11510 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heavy metal efflux pump YP_001470.1 1865972 R 267671 CDS YP_001471.1 45657385 2771725 complement(1869234..1869770) 1 NC_005823.1 PDF; cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1869770 def 2771725 def Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peptide deformylase YP_001471.1 1869234 R 267671 CDS YP_001472.1 45657386 2771441 complement(1869773..1870453) 1 NC_005823.1 hypothetical protein 1870453 2771441 LIC11512 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001472.1 1869773 R 267671 CDS YP_001473.1 45657387 2772787 1870683..1871051 1 NC_005823.1 hypothetical protein 1871051 2772787 LIC11514 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001473.1 1870683 D 267671 CDS YP_001474.1 45657388 2770236 1871066..1873882 1 NC_005823.1 hypothetical protein 1873882 2770236 LIC11515 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001474.1 1871066 D 267671 CDS YP_001475.1 45657389 2772808 1873866..1874195 1 NC_005823.1 anti-sigma factor antagonist 1874195 2772808 LIC11516 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_001475.1 1873866 D 267671 CDS YP_001476.1 45657390 2771859 1874272..1875939 1 NC_005823.1 acetyl-CoA carboxylase subunit alpha 1875939 accA2 2771859 accA2 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyl-CoA carboxylase subunit alpha YP_001476.1 1874272 D 267671 CDS YP_001477.1 45657391 2771149 1875946..1878690 1 NC_005823.1 biotin carboxylase subunit of acetyl CoA carboxylase 1878690 2771149 LIC11518 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 biotin carboxylase subunit of acetyl CoA carboxylase YP_001477.1 1875946 D 267671 CDS YP_001478.1 45657392 2770257 complement(1878764..1879102) 1 NC_005823.1 lipoprotein 1879102 2770257 LIC11519 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001478.1 1878764 R 267671 CDS YP_001479.1 45657393 2771487 complement(1879514..1880557) 1 NC_005823.1 protein-glutamate methylesterase 1880557 cheB 2771487 cheB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 protein-glutamate methylesterase YP_001479.1 1879514 R 267671 CDS YP_001480.1 45657394 2771146 complement(1880554..1881054) 1 NC_005823.1 chemotaxis protein 1881054 2771146 LIC11521 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chemotaxis protein YP_001480.1 1880554 R 267671 CDS YP_001481.1 45657395 2772830 complement(1881051..1881566) 1 NC_005823.1 chemotaxis protein 1881566 cheW 2772830 cheW Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chemotaxis protein YP_001481.1 1881051 R 267671 CDS YP_001482.1 45657396 2771079 complement(1881579..1884509) 1 NC_005823.1 chemotaxis protein 1884509 mcp 2771079 mcp Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chemotaxis protein YP_001482.1 1881579 R 267671 CDS YP_001483.1 45657397 2771197 complement(1884554..1886695) 1 NC_005823.1 chemotaxis protein histidine kinase 1886695 2771197 LIC11524 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chemotaxis protein histidine kinase YP_001483.1 1884554 R 267671 CDS YP_001484.1 45657398 2771760 complement(1886699..1887073) 1 NC_005823.1 anti-sigma factor antagonist 1887073 2771760 LIC11525 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_001484.1 1886699 R 267671 CDS YP_001485.1 45657399 2770078 complement(1887070..1887432) 1 NC_005823.1 chemotaxis response regulator 1887432 cheY 2770078 cheY Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chemotaxis response regulator YP_001485.1 1887070 R 267671 CDS YP_001486.1 45657400 2771167 complement(1887446..1888708) 1 NC_005823.1 histidine kinase response regulator hybrid protein 1888708 2771167 LIC11527 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase response regulator hybrid protein YP_001486.1 1887446 R 267671 CDS YP_001487.1 45657401 2772730 complement(1888671..1890866) 1 NC_005823.1 histidine kinase sensor protein 1890866 2772730 LIC11528 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_001487.1 1888671 R 267671 CDS YP_001488.1 45657402 2772545 complement(1891457..1892449) 1 NC_005823.1 penicillin tolerance protein 1892449 lytB 2772545 lytB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 penicillin tolerance protein YP_001488.1 1891457 R 267671 CDS YP_001489.1 45657403 2771379 complement(1892571..1893185) 1 NC_005823.1 hypothetical protein 1893185 2771379 LIC11530 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001489.1 1892571 R 267671 CDS YP_001490.1 45657404 2771574 1893643..1894491 1 NC_005823.1 flagellin protein 1894491 2771574 LIC11531 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellin protein YP_001490.1 1893643 D 267671 CDS YP_001491.1 45657405 2772123 complement(1895072..1895929) 1 NC_005823.1 flagellin protein 1895929 2772123 LIC11532 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellin protein YP_001491.1 1895072 R 267671 CDS YP_001492.1 45657406 2771804 1895975..1896286 1 NC_005823.1 hypothetical protein 1896286 2771804 LIC11533 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001492.1 1895975 D 267671 CDS YP_001493.1 45657407 2771176 1896261..1896812 1 NC_005823.1 hypothetical protein 1896812 2771176 LIC11534 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001493.1 1896261 D 267671 CDS YP_001494.1 45657408 2771066 1896788..1898092 1 NC_005823.1 di-tripeptide proton symporter 1898092 2771066 LIC11535 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 di-tripeptide proton symporter YP_001494.1 1896788 D 267671 CDS YP_001495.1 45657409 2771046 1898142..1899413 1 NC_005823.1 hypothetical protein 1899413 2771046 LIC11536 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001495.1 1898142 D 267671 CDS YP_001496.1 45657410 2771769 complement(1899705..1900358) 1 NC_005823.1 ATP-dependent protease-like La 1900358 2771769 LIC11537 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent protease-like La YP_001496.1 1899705 R 267671 CDS YP_001497.1 45657411 2772503 1900380..1901393 1 NC_005823.1 ADP-heptose synthase 1901393 rfaE2 2772503 rfaE2 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ADP-heptose synthase YP_001497.1 1900380 D 267671 CDS YP_001498.1 45657412 2772628 1901394..1901870 1 NC_005823.1 glycerol-3-phosphate cytidyltransferase 1901870 tagD 2772628 tagD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycerol-3-phosphate cytidyltransferase YP_001498.1 1901394 D 267671 CDS YP_001499.1 45657413 2771421 1902057..1903685 1 NC_005823.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1903685 pyrG 2771421 pyrG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 CTP synthetase YP_001499.1 1902057 D 267671 CDS YP_001500.1 45657414 2770248 1903682..1904551 1 NC_005823.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1904551 kdsA 2770248 kdsA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 2-dehydro-3-deoxyphosphooctonate aldolase YP_001500.1 1903682 D 267671 CDS YP_001501.1 45657415 2771468 1904563..1905147 1 NC_005823.1 hypothetical protein 1905147 2771468 LIC11542 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001501.1 1904563 D 267671 CDS YP_001502.1 45657416 2771100 1905144..1906514 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 1906514 2771100 LIC11543 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001502.1 1905144 D 267671 CDS YP_001503.1 45657417 2772036 1906527..1907252 1 NC_005823.1 ABC transporter ATP-binding protein 1907252 2772036 LIC11544 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_001503.1 1906527 D 267671 CDS YP_001504.1 45657418 2772755 1907249..1908670 1 NC_005823.1 RNA polymerase sigma-54 factor 1908670 rpoN 2772755 rpoN Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA polymerase sigma-54 factor YP_001504.1 1907249 D 267671 CDS YP_001505.1 45657419 2771977 1908675..1909640 1 NC_005823.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 1909640 ptsK 2771977 ptsK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 HPr kinase/phosphorylase YP_001505.1 1908675 D 267671 CDS YP_001506.1 45657420 2771386 1909654..1909875 1 NC_005823.1 phosphocarrier protein HPr 1909875 ptsH 2771386 ptsH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphocarrier protein HPr YP_001506.1 1909654 D 267671 CDS YP_001507.1 45657421 2772791 1909889..1911679 1 NC_005823.1 histidine kinase sensor protein 1911679 2772791 LIC11548 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_001507.1 1909889 D 267671 CDS YP_001508.1 45657422 2772837 1911687..1913033 1 NC_005823.1 sigma 54 activator; response regulator 1913033 2772837 LIC11549 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_001508.1 1911687 D 267671 CDS YP_001509.1 45657423 2771577 1913026..1913877 1 NC_005823.1 hypothetical protein 1913877 2771577 LIC11550 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001509.1 1913026 D 267671 CDS YP_001510.1 45657424 2771154 1913874..1915817 1 NC_005823.1 primosomal protein N' 1915817 priA 2771154 priA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 primosomal protein N' YP_001510.1 1913874 D 267671 CDS YP_001511.1 45657425 2772823 1915944..1916891 1 NC_005823.1 methionyl-tRNA formyltransferase 1916891 fmt 2772823 fmt Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methionyl-tRNA formyltransferase YP_001511.1 1915944 D 267671 CDS YP_001512.1 45657426 2772124 1916888..1917883 1 NC_005823.1 serine/threonine kinase 1917883 2772124 LIC11553 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 serine/threonine kinase YP_001512.1 1916888 D 267671 CDS YP_001513.1 45657427 2772733 1917880..1918527 1 NC_005823.1 ribulose-5-phosphate 3-epimerase 1918527 rpe 2772733 rpe Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribulose-5-phosphate 3-epimerase YP_001513.1 1917880 D 267671 CDS YP_001514.2 161621775 2771732 1919300..1919566 1 NC_005823.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1919566 rpsP 2771732 rpsP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S16 YP_001514.2 1919300 D 267671 CDS YP_001515.1 45657429 2770967 1919566..1919796 1 NC_005823.1 contains KH domain; identified by sequence similarity; ORF located using Blastx/Glimmer; RNA-binding protein 1919796 2770967 LIC11556 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA-binding protein YP_001515.1 1919566 D 267671 CDS YP_001516.1 45657430 2772693 1919789..1920319 1 NC_005823.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1920319 rimM 2772693 rimM Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 16S rRNA-processing protein RimM YP_001516.1 1919789 D 267671 CDS YP_001517.1 45657431 2770199 1920309..1921004 1 NC_005823.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; Chlamydial proteins show a C-terminal extension of unknown function; tRNA (guanine-N(1)-)-methyltransferase/unknown domain fusion protein 1921004 trmD 2770199 trmD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tRNA (guanine-N(1)-)-methyltransferase/unknown domain fusion protein YP_001517.1 1920309 D 267671 CDS YP_001518.1 45657432 2771001 1920964..1921380 1 NC_005823.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1921380 rplS 2771001 rplS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L19 YP_001518.1 1920964 D 267671 CDS YP_001519.1 45657433 2772108 1921387..1922082 1 NC_005823.1 ribonuclease HII 1922082 rnhB 2772108 rnhB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribonuclease HII YP_001519.1 1921387 D 267671 CDS YP_001520.1 45657434 2770977 1922154..1922897 1 NC_005823.1 hypothetical protein 1922897 2770977 LIC11561 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001520.1 1922154 D 267671 CDS YP_001521.1 45657435 2772118 1922898..1923161 1 NC_005823.1 flagellar biosynthetic transmembrane protein 1923161 2772118 LIC11562 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar biosynthetic transmembrane protein YP_001521.1 1922898 D 267671 CDS YP_001522.1 45657436 2772633 1923158..1924342 1 NC_005823.1 hypothetical protein 1924342 2772633 LIC11563 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001522.1 1923158 D 267671 CDS YP_001523.1 45657437 2771408 1925052..1925402 1 NC_005823.1 hypothetical protein 1925402 2771408 LIC11564 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001523.1 1925052 D 267671 CDS YP_001524.1 45657438 2771887 1925498..1925695 1 NC_005823.1 hypothetical protein 1925695 2771887 LIC11565 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001524.1 1925498 D 267671 CDS YP_001525.1 45657439 2772570 complement(1925715..1927244) 1 NC_005823.1 ATPase with chaperone activity; Mg chelatase subunit ChII 1927244 2772570 LIC11566 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Mg chelatase subunit ChII YP_001525.1 1925715 R 267671 CDS YP_001526.1 45657440 2771923 1927403..1927777 1 NC_005823.1 lipoprotein 1927777 2771923 LIC11567 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001526.1 1927403 D 267671 CDS YP_001527.1 45657441 2771314 1927746..1928756 1 NC_005823.1 membrane peptidase 1928756 2771314 LIC11568 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 membrane peptidase YP_001527.1 1927746 D 267671 CDS YP_001528.1 45657442 2771834 1928812..1929720 1 NC_005823.1 hypothetical protein 1929720 2771834 LIC11569 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001528.1 1928812 D 267671 CDS YP_001529.1 45657443 2772240 1929725..1931515 1 NC_005823.1 general secretory pathway protein D 1931515 gspD 2772240 gspD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 general secretory pathway protein D YP_001529.1 1929725 D 267671 CDS YP_001530.1 45657444 2771200 1931519..1933192 1 NC_005823.1 general secretory pathway protein E 1933192 gspE 2771200 gspE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 general secretory pathway protein E YP_001530.1 1931519 D 267671 CDS YP_001531.1 45657445 2770300 1933198..1934424 1 NC_005823.1 general secretory pathway protein F 1934424 gspF 2770300 gspF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 general secretory pathway protein F YP_001531.1 1933198 D 267671 CDS YP_001532.1 45657446 2770373 1934446..1934922 1 NC_005823.1 general secretory pathway protein G 1934922 gspG 2770373 gspG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 general secretory pathway protein G YP_001532.1 1934446 D 267671 CDS YP_001533.1 45657447 2771568 1934944..1935513 1 NC_005823.1 hypothetical protein 1935513 2771568 LIC11574 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001533.1 1934944 D 267671 CDS YP_001534.1 45657448 2770213 1935488..1936024 1 NC_005823.1 hypothetical protein 1936024 2770213 LIC11575 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001534.1 1935488 D 267671 CDS YP_001535.1 45657449 2771443 1936034..1936678 1 NC_005823.1 hypothetical protein 1936678 2771443 LIC11576 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001535.1 1936034 D 267671 CDS YP_001536.1 45657450 2772742 1936842..1938017 1 NC_005823.1 type II secretion pathway related protein etpK-like protein 1938017 2772742 LIC11577 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 type II secretion pathway related protein etpK-like protein YP_001536.1 1936842 D 267671 CDS YP_001537.1 45657451 2770148 1938023..1939645 1 NC_005823.1 cell division protein; hypothetical protein 1939645 2770148 LIC11578 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001537.1 1938023 D 267671 CDS YP_001538.1 45657452 2772831 1939653..1940180 1 NC_005823.1 hypothetical protein 1940180 2772831 LIC11579 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001538.1 1939653 D 267671 CDS YP_001539.1 45657453 2772336 1940177..1941118 1 NC_005823.1 hypothetical protein 1941118 2772336 LIC11580 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001539.1 1940177 D 267671 CDS YP_001540.1 45657454 2771656 1941231..1941974 1 NC_005823.1 hypothetical protein 1941974 2771656 LIC11581 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001540.1 1941231 D 267671 CDS YP_001541.1 45657455 2772581 1942088..1942315 1 NC_005823.1 hypothetical protein 1942315 2772581 LIC11582 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001541.1 1942088 D 267671 CDS YP_001542.1 45657456 2771527 1942479..1942745 1 NC_005823.1 hypothetical protein 1942745 2771527 LIC11583 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001542.1 1942479 D 267671 CDS YP_001543.1 45657457 2771620 complement(1942994..1943596) 1 NC_005823.1 TetR family transcriptional regulator 1943596 2771620 LIC11584 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 TetR family transcriptional regulator YP_001543.1 1942994 R 267671 CDS YP_001544.1 45657458 2771141 1943843..1944067 1 NC_005823.1 tautomerase 1944067 2771141 LIC11585 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tautomerase YP_001544.1 1943843 D 267671 CDS YP_001545.1 45657459 2770582 1944091..1945149 1 NC_005823.1 alcohol dehydrogenase 1945149 2770582 LIC11586 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alcohol dehydrogenase YP_001545.1 1944091 D 267671 CDS YP_001546.1 45657460 2772842 complement(1945319..1948948) 1 NC_005823.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1948948 nrdA 2772842 nrdA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribonucleotide-diphosphate reductase subunit alpha YP_001546.1 1945319 R 267671 CDS YP_001547.1 45657461 2771710 complement(1949389..1949622) 1 NC_005823.1 hypothetical protein 1949622 2771710 LIC11589 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001547.1 1949389 R 267671 CDS YP_001548.1 45657462 2771536 complement(1949939..1950226) 1 NC_005823.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1950226 2771536 LIC11590 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 exodeoxyribonuclease VII small subunit YP_001548.1 1949939 R 267671 CDS YP_001549.1 45657463 2771875 complement(1950228..1951496) 1 NC_005823.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1951496 xseA 2771875 xseA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 exodeoxyribonuclease VII large subunit YP_001549.1 1950228 R 267671 CDS YP_001550.1 45657464 2772387 complement(1951500..1952630) 1 NC_005823.1 permease 1952630 2772387 LIC11592 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 permease YP_001550.1 1951500 R 267671 CDS YP_003858663.1 304570508 9714942 complement(1952637..1952930) 1 NC_005823.1 hypothetical protein 1952930 9714942 LIC14001 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003858663.1 1952637 R 267671 CDS YP_001552.1 45657466 2771324 1953230..1953871 1 NC_005823.1 hypothetical protein 1953871 2771324 LIC11594 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001552.1 1953230 D 267671 CDS YP_001553.1 45657467 2770492 complement(1954261..1955820) 1 NC_005823.1 hypothetical protein 1955820 2770492 LIC11595 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001553.1 1954261 R 267671 CDS YP_001554.1 45657468 2772793 1955910..1956278 1 NC_005823.1 DNA mismatch repair protein 1956278 2772793 LIC11596 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA mismatch repair protein YP_001554.1 1955910 D 267671 CDS YP_001555.1 45657469 2772469 1956275..1957825 1 NC_005823.1 2-isopropylmalate synthase 2 1957825 leuA2 2772469 leuA2 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 2-isopropylmalate synthase 2 YP_001555.1 1956275 D 267671 CDS YP_001556.1 45657470 2769927 1957813..1958385 1 NC_005823.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1958385 pth 2769927 pth Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peptidyl-tRNA hydrolase YP_001556.1 1957813 D 267671 CDS YP_001557.1 45657471 2771249 1958542..1959540 1 NC_005823.1 integrase/recombinase protein 1959540 xerC 2771249 xerC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 integrase/recombinase protein YP_001557.1 1958542 D 267671 CDS YP_001558.1 45657472 2771201 1959527..1960069 1 NC_005823.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 1960069 hslV 2771201 hslV Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent protease peptidase subunit YP_001558.1 1959527 D 267671 CDS YP_001559.1 45657473 2771372 1960079..1961518 1 NC_005823.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 1961518 hslU 2771372 hslU Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent protease ATP-binding subunit HslU YP_001559.1 1960079 D 267671 CDS YP_001560.1 45657474 2772611 1962812..1964317 1 NC_005823.1 hypothetical protein 1964317 2772611 LIC11602 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001560.1 1962812 D 267671 CDS YP_001561.1 45657475 2772033 complement(1964537..1965055) 1 NC_005823.1 hypothetical protein 1965055 2772033 LIC11603 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001561.1 1964537 R 267671 CDS YP_001562.1 45657476 2772862 complement(1965580..1966410) 1 NC_005823.1 hypothetical protein 1966410 2772862 LIC11604 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001562.1 1965580 R 267671 CDS YP_001563.1 45657477 2772873 1966478..1966738 1 NC_005823.1 dihydrolipoamide acetyltransferase 1966738 2772873 LIC11605 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dihydrolipoamide acetyltransferase YP_001563.1 1966478 D 267671 CDS YP_001564.1 45657478 2769861 1966735..1967613 1 NC_005823.1 hypothetical protein 1967613 2769861 LIC11606 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001564.1 1966735 D 267671 CDS YP_001565.1 45657479 2770155 1967615..1968658 1 NC_005823.1 cell division ATPase 1968658 mrp 2770155 mrp Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cell division ATPase YP_001565.1 1967615 D 267671 CDS YP_001566.1 45657480 2772930 1968705..1969394 1 NC_005823.1 hypothetical protein 1969394 2772930 LIC11608 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001566.1 1968705 D 267671 CDS YP_001567.1 45657481 2769523 complement(1969401..1970015) 1 NC_005823.1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 1970015 ubiX 2769523 ubiX Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001567.1 1969401 R 267671 CDS YP_001568.1 45657482 2772872 complement(1971616..1972548) 1 NC_005823.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; prenyltransferase 1972548 ubiA 2772872 ubiA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 prenyltransferase YP_001568.1 1971616 R 267671 CDS YP_001569.1 45657483 2772908 1972611..1973258 1 NC_005823.1 hypothetical protein 1973258 2772908 LIC11611 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001569.1 1972611 D 267671 CDS YP_001570.1 45657484 2769517 1973265..1974518 1 NC_005823.1 hypothetical protein 1974518 2769517 LIC11612 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001570.1 1973265 D 267671 CDS YP_001571.1 45657485 2769786 1974564..1975661 1 NC_005823.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1975661 ychF 2769786 ychF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GTP-dependent nucleic acid-binding protein EngD YP_001571.1 1974564 D 267671 CDS YP_001572.1 45657486 2769604 1975744..1976871 1 NC_005823.1 A/G specific adenine glycosylase 1976871 mutY 2769604 mutY Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 A/G specific adenine glycosylase YP_001572.1 1975744 D 267671 CDS YP_001573.1 45657487 2769531 1976868..1978625 1 NC_005823.1 hypothetical protein 1978625 2769531 LIC11615 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001573.1 1976868 D 267671 CDS YP_001574.1 45657488 2769614 1978631..1979611 1 NC_005823.1 ADP-L-glycero-D-mannoheptose-6-epimerase 1979611 rfaD 2769614 rfaD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ADP-L-glycero-D-mannoheptose-6-epimerase YP_001574.1 1978631 D 267671 CDS YP_001575.1 45657489 2769729 complement(1979639..1979938) 1 NC_005823.1 ArsR family transcriptional regulator 1979938 2769729 LIC11617 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ArsR family transcriptional regulator YP_001575.1 1979639 R 267671 CDS YP_001576.1 45657490 2769779 complement(1980115..1980885) 1 NC_005823.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1980885 fabG 2769779 fabG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-ketoacyl-ACP reductase YP_001576.1 1980115 R 267671 CDS YP_001577.1 45657491 2769737 complement(1980875..1981579) 1 NC_005823.1 hypothetical protein 1981579 2769737 LIC11619 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001577.1 1980875 R 267671 CDS YP_001578.1 45657492 2769525 1982343..1984049 1 NC_005823.1 DNA repair protein 1984049 recN 2769525 recN Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA repair protein YP_001578.1 1982343 D 267671 CDS YP_001579.1 45657493 2769637 1984161..1984766 1 NC_005823.1 biopolymer transport protein 1984766 tolQ 2769637 tolQ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 biopolymer transport protein YP_001579.1 1984161 D 267671 CDS YP_001580.1 45657494 2771755 1984769..1985218 1 NC_005823.1 biopolymer transport exbd-related transmembrane protein 1985218 2771755 LIC11622 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 biopolymer transport exbd-related transmembrane protein YP_001580.1 1984769 D 267671 CDS YP_001581.1 45657495 2771428 1985237..1988164 1 NC_005823.1 outer membrane protein 1988164 2771428 LIC11623 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 outer membrane protein YP_001581.1 1985237 D 267671 CDS YP_001582.1 45657496 2771530 1988168..1990366 1 NC_005823.1 ATP-dependent DNA helicase 1990366 uvrD 2771530 uvrD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent DNA helicase YP_001582.1 1988168 D 267671 CDS YP_001583.1 45657497 2772375 1990429..1990869 1 NC_005823.1 hypothetical protein 1990869 2772375 LIC11625 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001583.1 1990429 D 267671 CDS YP_001584.1 45657498 2772199 1990894..1991739 1 NC_005823.1 inositol monophosphatase family protein 1991739 2772199 LIC11626 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 inositol monophosphatase family protein YP_001584.1 1990894 D 267671 CDS YP_001585.1 45657499 2771206 1991768..1993000 1 NC_005823.1 mannosyltransferase 1993000 mtf 2771206 mtf Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 mannosyltransferase YP_001585.1 1991768 D 267671 CDS YP_001586.1 45657500 2771589 complement(1993856..1994380) 1 NC_005823.1 hypothetical protein 1994380 2771589 LIC11628 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001586.1 1993856 R 267671 CDS YP_001587.1 45657501 2771482 1994379..1994876 1 NC_005823.1 thiol:disulfide interchange protein 1994876 dsbA 2771482 dsbA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thiol:disulfide interchange protein YP_001587.1 1994379 D 267671 CDS YP_001588.1 45657502 2770997 1995293..1997338 1 NC_005823.1 long-chain-fatty-acid CoA ligase 1997338 fadD 2770997 fadD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 long-chain-fatty-acid CoA ligase YP_001588.1 1995293 D 267671 CDS YP_001589.1 45657503 2772342 1997433..1998113 1 NC_005823.1 hypothetical protein 1998113 2772342 LIC11631 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001589.1 1997433 D 267671 CDS YP_001590.1 45657504 2769596 complement(1998110..1999939) 1 NC_005823.1 phosphotransferase system enzyme I 1999939 ptsI 2769596 ptsI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphotransferase system enzyme I YP_001590.1 1998110 R 267671 CDS YP_001591.1 45657505 2771829 complement(1999985..2000998) 1 NC_005823.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2000998 lpxC 2771829 lpxC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_001591.1 1999985 R 267671 CDS YP_001592.1 45657506 2772450 complement(2001334..2002002) 1 NC_005823.1 CsgA 2002002 csgA 2772450 csgA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 CsgA YP_001592.1 2001334 R 267671 CDS YP_001593.1 45657507 2771140 2002085..2002750 1 NC_005823.1 internal repeat sequences detected; contains DUF124 domain as detected by pfam-hmmr; hypothetical protein 2002750 2771140 LIC11635 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001593.1 2002085 D 267671 CDS YP_001594.1 45657508 2770235 2002766..2003440 1 NC_005823.1 internal repeat sequences detected; contains DUF124 domain as detected by pfam-hmmr; hypothetical protein 2003440 2770235 LIC11636 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001594.1 2002766 D 267671 CDS YP_001595.1 45657509 2771571 2003453..2004133 1 NC_005823.1 hypothetical protein 2004133 2771571 LIC11637 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001595.1 2003453 D 267671 CDS YP_001596.1 45657510 2772099 complement(2004163..2004357) 1 NC_005823.1 hypothetical protein 2004357 2772099 LIC11638 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001596.1 2004163 R 267671 CDS YP_001597.1 45657511 2770365 complement(2004459..2005568) 1 NC_005823.1 hypothetical protein 2005568 2770365 LIC11639 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001597.1 2004459 R 267671 CDS YP_001598.1 45657512 2772031 complement(2006124..2006384) 1 NC_005823.1 hypothetical protein 2006384 2772031 LIC11640 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001598.1 2006124 R 267671 CDS YP_001599.1 45657513 2771196 complement(2006426..2007736) 1 NC_005823.1 hypothetical protein 2007736 2771196 LIC11641 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001599.1 2006426 R 267671 CDS YP_001600.1 45657514 2770596 2007962..2009311 1 NC_005823.1 hypothetical protein 2009311 2770596 LIC11642 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001600.1 2007962 D 267671 CDS YP_001601.1 45657515 2770102 2009405..2010577 1 NC_005823.1 lipoprotein; Qlp42; hypothetical protein 2010577 2770102 LIC11643 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001601.1 2009405 D 267671 CDS YP_001602.1 45657516 2771484 2011426..2011755 1 NC_005823.1 hypothetical protein 2011755 2771484 LIC11644 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001602.1 2011426 D 267671 CDS YP_001603.1 45657517 2769767 complement(2011883..2012182) 1 NC_005823.1 hypothetical protein 2012182 2769767 LIC11645 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001603.1 2011883 R 267671 CDS YP_001604.1 45657518 2771666 complement(2012170..2013075) 1 NC_005823.1 catalyzes the radical-mediated insertion of two sulfur atoms into an ACP ACP bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 2013075 lipA 2771666 lipA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoyl synthase YP_001604.1 2012170 R 267671 CDS YP_001605.1 45657519 2771219 2013175..2013915 1 NC_005823.1 pseudouridylate synthase 2013915 2771219 LIC11647 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pseudouridylate synthase YP_001605.1 2013175 D 267671 CDS YP_001606.1 45657520 2772499 2015341..2016366 1 NC_005823.1 hypothetical protein 2016366 2772499 LIC11650 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001606.1 2015341 D 267671 CDS YP_001607.1 45657521 2769826 complement(2017543..2017818) 1 NC_005823.1 hypothetical protein 2017818 2769826 LIC11651 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001607.1 2017543 R 267671 CDS YP_001608.1 45657522 2771660 complement(2017973..2018617) 1 NC_005823.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase 2018617 tal 2771660 tal Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 translaldolase YP_001608.1 2017973 R 267671 CDS YP_001609.1 45657523 2772905 complement(2018797..2019528) 1 NC_005823.1 hypothetical protein 2019528 2772905 LIC11653 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001609.1 2018797 R 267671 CDS YP_001610.1 45657524 2772784 complement(2019559..2020185) 1 NC_005823.1 hypothetical protein 2020185 2772784 LIC11654 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001610.1 2019559 R 267671 CDS YP_001611.1 45657525 2772360 complement(2020188..2021723) 1 NC_005823.1 bifunctional purine biosynthesis protein; involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 2021723 purH 2772360 purH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_001611.1 2020188 R 267671 CDS YP_001612.1 45657526 2771722 complement(2021727..2022353) 1 NC_005823.1 phosphoribosylglycinamide formyltransferase 2022353 purN 2771722 purN Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoribosylglycinamide formyltransferase YP_001612.1 2021727 R 267671 CDS YP_001613.1 45657527 2771630 2022767..2023219 1 NC_005823.1 flagellar protein; hypothetical protein 2023219 fliS 2771630 fliS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001613.1 2022767 D 267671 CDS YP_001614.1 45657528 2769950 2023216..2023644 1 NC_005823.1 hypothetical protein 2023644 2769950 LIC11658 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001614.1 2023216 D 267671 CDS YP_001615.1 45657529 2770541 2023623..2024120 1 NC_005823.1 hypothetical protein 2024120 2770541 LIC11659 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001615.1 2023623 D 267671 CDS YP_001616.1 45657530 2772239 complement(2024107..2024604) 1 NC_005823.1 lipoprotein 2024604 2772239 LIC11660 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001616.1 2024107 R 267671 CDS YP_001617.1 45657531 2772643 complement(2024601..2025155) 1 NC_005823.1 HNH endonuclease family protein 2025155 2772643 LIC11661 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 HNH endonuclease family protein YP_001617.1 2024601 R 267671 CDS YP_001618.1 45657532 2772413 complement(2025207..2025812) 1 NC_005823.1 dedA family; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 2025812 2772413 LIC11662 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001618.1 2025207 R 267671 CDS YP_001619.1 45657533 2772661 2025936..2027081 1 NC_005823.1 deoxyguanosinetriphosphate triphosphohydrolase 2027081 dgt 2772661 dgt Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 deoxyguanosinetriphosphate triphosphohydrolase YP_001619.1 2025936 D 267671 CDS YP_001620.1 45657534 2770623 complement(2027173..2027904) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 2027904 2770623 LIC11664 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001620.1 2027173 R 267671 CDS YP_001621.1 45657535 2770871 complement(2027972..2028526) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 2028526 2770871 LIC11665 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001621.1 2027972 R 267671 CDS YP_001622.1 45657536 2771139 complement(2030366..2031646) 1 NC_005823.1 hypothetical protein 2031646 2771139 LIC11668 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001622.1 2030366 R 267671 CDS YP_001623.1 45657537 2772060 complement(2031621..2031875) 1 NC_005823.1 hypothetical protein 2031875 2772060 LIC11669 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001623.1 2031621 R 267671 CDS YP_001624.1 45657538 2771608 2032002..2033768 1 NC_005823.1 hypothetical protein 2033768 2771608 LIC11670 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001624.1 2032002 D 267671 CDS YP_001625.1 45657539 2772185 2033775..2034569 1 NC_005823.1 hypothetical protein 2034569 2772185 LIC11671 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001625.1 2033775 D 267671 CDS YP_001626.1 45657540 2772902 2034761..2035528 1 NC_005823.1 enoyl-CoA hydratase 2035528 2772902 LIC11672 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 enoyl-CoA hydratase YP_001626.1 2034761 D 267671 CDS YP_001627.1 45657541 2772335 complement(2035699..2036841) 1 NC_005823.1 ankyrin 2036841 ank2 2772335 ank2 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ankyrin YP_001627.1 2035699 R 267671 CDS YP_001628.1 45657542 2770825 complement(2036838..2038529) 1 NC_005823.1 alkylglycerone-phosphate synthase 2038529 2770825 LIC11674 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alkylglycerone-phosphate synthase YP_001628.1 2036838 R 267671 CDS YP_001629.1 45657543 2770937 2038703..2040361 1 NC_005823.1 glycerol-3-phosphate dehydrogenase 2040361 2770937 LIC11675 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycerol-3-phosphate dehydrogenase YP_001629.1 2038703 D 267671 CDS YP_001630.1 45657544 2771837 complement(2040366..2041019) 1 NC_005823.1 TetR family transcriptional regulator 2041019 2771837 LIC11676 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 TetR family transcriptional regulator YP_001630.1 2040366 R 267671 CDS YP_001631.1 45657545 2771819 complement(2041033..2041524) 1 NC_005823.1 hypothetical protein 2041524 2771819 LIC11677 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001631.1 2041033 R 267671 CDS YP_001632.1 45657546 2772585 complement(2041811..2042638) 1 NC_005823.1 hypothetical protein 2042638 2772585 LIC11678 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001632.1 2041811 R 267671 CDS YP_001633.1 45657547 2770141 2042711..2043214 1 NC_005823.1 hypothetical protein 2043214 2770141 LIC11679 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001633.1 2042711 D 267671 CDS YP_001634.1 45657548 2769599 2044713..2045783 1 NC_005823.1 hypothetical protein 2045783 2769599 LIC11682 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001634.1 2044713 D 267671 CDS YP_001635.1 45657549 2772023 complement(2046178..2046630) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 2046630 2772023 LIC11683 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001635.1 2046178 R 267671 CDS YP_001636.1 45657550 2771862 complement(2046831..2047571) 1 NC_005823.1 Sir2 transcriptional regulator 2047571 2771862 LIC11684 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Sir2 transcriptional regulator YP_001636.1 2046831 R 267671 CDS YP_001637.1 45657551 2772107 complement(2047568..2048113) 1 NC_005823.1 hypothetical protein 2048113 2772107 LIC11685 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001637.1 2047568 R 267671 CDS YP_001638.1 45657552 2771675 2048212..2049390 1 NC_005823.1 hypothetical protein 2049390 2771675 LIC11686 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001638.1 2048212 D 267671 CDS YP_001639.1 45657553 2771387 2050145..2051071 1 NC_005823.1 endonuclease 2051071 2771387 LIC11687 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 endonuclease YP_001639.1 2050145 D 267671 CDS YP_001640.1 45657554 2770767 complement(2051385..2051894) 1 NC_005823.1 hypothetical protein 2051894 2770767 LIC11688 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001640.1 2051385 R 267671 CDS YP_001641.1 45657555 2770284 complement(2051891..2052265) 1 NC_005823.1 hypothetical protein 2052265 2770284 LIC11689 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001641.1 2051891 R 267671 CDS YP_001642.1 45657556 2772150 complement(2053166..2053492) 1 NC_005823.1 hypothetical protein 2053492 2772150 LIC11690 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001642.1 2053166 R 267671 CDS YP_001643.1 45657557 2770230 complement(2054053..2055561) 1 NC_005823.1 methyl-accepting chemotaxis protein 2055561 mcp-2 2770230 mcp-2 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methyl-accepting chemotaxis protein YP_001643.1 2054053 R 267671 CDS YP_001644.1 45657558 2770528 2055610..2055840 1 NC_005823.1 hypothetical protein 2055840 2770528 LIC11692 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001644.1 2055610 D 267671 CDS YP_001645.1 45657559 2771029 2056599..2057099 1 NC_005823.1 hypothetical protein 2057099 2771029 LIC11693 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001645.1 2056599 D 267671 CDS YP_001646.1 45657560 2772355 2058318..2060726 1 NC_005823.1 TonB-dependent outer membrane receptor 2060726 2772355 LIC11694 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 TonB-dependent outer membrane receptor YP_001646.1 2058318 D 267671 CDS YP_001647.1 45657561 2772695 2060753..2061313 1 NC_005823.1 hypothetical protein 2061313 2772695 LIC11695 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001647.1 2060753 D 267671 CDS YP_001648.1 45657562 2771479 2061749..2062327 1 NC_005823.1 hypothetical protein 2062327 2771479 LIC11696 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001648.1 2061749 D 267671 CDS YP_001649.1 45657563 2769817 complement(2062735..2063931) 1 NC_005823.1 xylanase/chitin deacetylase 2063931 2769817 LIC11697 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 xylanase/chitin deacetylase YP_001649.1 2062735 R 267671 CDS YP_001650.1 45657564 2771607 complement(2063977..2065194) 1 NC_005823.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 2065194 tyrS 2771607 tyrS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tyrosyl-tRNA synthetase YP_001650.1 2063977 R 267671 CDS YP_001651.1 45657565 2771844 2065227..2066879 1 NC_005823.1 glycerol-3-phosphate dehydrogenase 2066879 glpD 2771844 glpD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycerol-3-phosphate dehydrogenase YP_001651.1 2065227 D 267671 CDS YP_001652.1 45657566 2770215 2066939..2067136 1 NC_005823.1 hypothetical protein 2067136 2770215 LIC11700 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001652.1 2066939 D 267671 CDS YP_001653.1 45657567 2771702 complement(2067509..2069266) 1 NC_005823.1 RNA polymerase sigma-70 factor 2069266 rpoD 2771702 rpoD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA polymerase sigma-70 factor YP_001653.1 2067509 R 267671 CDS YP_001654.1 45657568 2771747 complement(2069283..2071079) 1 NC_005823.1 DNA primase 2071079 dnaG 2771747 dnaG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA primase YP_001654.1 2069283 R 267671 CDS YP_001655.1 45657569 2770996 complement(2071098..2071544) 1 NC_005823.1 hypothetical protein 2071544 2770996 LIC11703 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001655.1 2071098 R 267671 CDS YP_001656.1 45657570 2771802 complement(2071604..2071813) 1 NC_005823.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 2071813 rpsU 2771802 rpsU Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S21 YP_001656.1 2071604 R 267671 CDS YP_001657.1 45657571 2769804 2072013..2072306 1 NC_005823.1 hypothetical protein 2072306 2769804 LIC11705 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001657.1 2072013 D 267671 CDS YP_001658.1 45657572 2771153 complement(2072313..2072756) 1 NC_005823.1 hypothetical protein 2072756 2771153 LIC11706 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001658.1 2072313 R 267671 CDS YP_001659.1 45657573 2771405 2072824..2073948 1 NC_005823.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 2073948 fbp 2771405 fbp Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 fructose-1,6-bisphosphatase YP_001659.1 2072824 D 267671 CDS YP_001660.1 45657574 2769953 complement(2074740..2075888) 1 NC_005823.1 histidine kinase response regulator hybrid protein 2075888 2769953 LIC11708 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase response regulator hybrid protein YP_001660.1 2074740 R 267671 CDS YP_001661.1 45657575 2770037 complement(2075927..2078425) 1 NC_005823.1 histidine kinase response regulator hybrid protein 2078425 2770037 LIC11709 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase response regulator hybrid protein YP_001661.1 2075927 R 267671 CDS YP_001662.1 45657576 2769857 complement(2079062..2081593) 1 NC_005823.1 ATPase P 2081593 mgtB 2769857 mgtB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATPase P YP_001662.1 2079062 R 267671 CDS YP_001663.1 45657577 2771209 complement(2082319..2082969) 1 NC_005823.1 lipoprotein 2082969 2771209 LIC11711 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001663.1 2082319 R 267671 CDS YP_001664.1 45657578 2770754 complement(2083177..2084568) 1 NC_005823.1 magnesium transporter 2084568 mgtE 2770754 mgtE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 magnesium transporter YP_001664.1 2083177 R 267671 CDS YP_001665.2 304570492 2771592 2084708..2085718 1 NC_005823.1 motility protein B 2085718 2771592 LIC11713 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 motility protein B YP_001665.2 2084708 D 267671 CDS YP_001666.1 45657580 2771012 2085715..2086668 1 NC_005823.1 heavy metal efflux pump 2086668 czcD 2771012 czcD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heavy metal efflux pump YP_001666.1 2085715 D 267671 CDS YP_001667.1 45657581 2771336 complement(2086747..2087001) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 2087001 2771336 LIC11715 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001667.1 2086747 R 267671 CDS YP_001668.1 45657582 2770303 complement(2087058..2088107) 1 NC_005823.1 hypothetical protein 2088107 2770303 LIC11716 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001668.1 2087058 R 267671 CDS YP_001669.1 45657583 2771006 complement(2088124..2090970) 1 NC_005823.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 2090970 uvrA 2771006 uvrA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 excinuclease ABC subunit A YP_001669.1 2088124 R 267671 CDS YP_001670.1 45657584 2772415 2091080..2092819 1 NC_005823.1 protease IV 2092819 2772415 LIC11718 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 protease IV YP_001670.1 2091080 D 267671 CDS YP_001671.1 45657585 2772104 complement(2094502..2095449) 1 NC_005823.1 hypothetical protein 2095449 2772104 LIC11719 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001671.1 2094502 R 267671 CDS YP_001672.1 45657586 2770224 complement(2095430..2097037) 1 NC_005823.1 hypothetical protein 2097037 2770224 LIC11720 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001672.1 2095430 R 267671 CDS YP_001673.1 45657587 2771208 2097132..2097908 1 NC_005823.1 hypothetical protein 2097908 2771208 LIC11721 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001673.1 2097132 D 267671 CDS YP_001674.1 45657588 2772493 2098067..2098585 1 NC_005823.1 hypothetical protein 2098585 2772493 LIC11722 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001674.1 2098067 D 267671 CDS YP_001675.1 45657589 2771147 2098598..2099164 1 NC_005823.1 lipoprotein 2099164 2771147 LIC11723 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001675.1 2098598 D 267671 CDS YP_001676.1 45657590 2772571 2099731..2100237 1 NC_005823.1 hypothetical protein 2100237 2772571 LIC11724 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001676.1 2099731 D 267671 CDS YP_001677.1 45657591 2771000 complement(2100357..2100689) 1 NC_005823.1 hypothetical protein 2100689 2771000 LIC11725 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001677.1 2100357 R 267671 CDS YP_001678.1 45657592 2770298 2100758..2102344 1 NC_005823.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 2102344 leuA 2770298 leuA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 2-isopropylmalate synthase YP_001678.1 2100758 D 267671 CDS YP_001679.1 45657593 2770509 2102484..2102669 1 NC_005823.1 hypothetical protein 2102669 2770509 LIC11727 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001679.1 2102484 D 267671 CDS YP_001680.1 45657594 2772067 complement(2102702..2103262) 1 NC_005823.1 N-acetylmuramoyl-L-alanine amidase 2103262 2772067 LIC11728 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 N-acetylmuramoyl-L-alanine amidase YP_001680.1 2102702 R 267671 CDS YP_001681.1 45657595 2769769 2103794..2105803 1 NC_005823.1 2,4-dienoyl-coa reductase 2105803 fadH 2769769 fadH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 2,4-dienoyl-coa reductase YP_001681.1 2103794 D 267671 CDS YP_001682.1 45657596 2772718 2108170..2109081 1 NC_005823.1 hypothetical protein 2109081 2772718 LIC11730 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001682.1 2108170 D 267671 CDS YP_003858664.1 304570514 9714932 2109340..2109693 1 NC_005823.1 hypothetical protein 2109693 9714932 LIC14007 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003858664.1 2109340 D 267671 CDS YP_001683.1 45657597 2769670 2109765..2110247 1 NC_005823.1 FKBP-type peptidyl-prolyl cis-trans isomerase 2110247 slyD 2769670 slyD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 FKBP-type peptidyl-prolyl cis-trans isomerase YP_001683.1 2109765 D 267671 CDS YP_001684.1 45657598 2769566 2110228..2112246 1 NC_005823.1 ATP-dependent DNA helicase 2112246 uvrD2 2769566 uvrD2 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent DNA helicase YP_001684.1 2110228 D 267671 CDS YP_001685.1 45657599 2771649 2112236..2113003 1 NC_005823.1 hypothetical protein 2113003 2771649 LIC11733 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001685.1 2112236 D 267671 CDS YP_001686.1 45657600 2769518 2113053..2113250 1 NC_005823.1 hypothetical protein 2113250 2769518 LIC11734 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001686.1 2113053 D 267671 CDS YP_001687.1 45657601 2771071 2113252..2114049 1 NC_005823.1 2-dehydropantoate 2-reductase 2114049 apbA 2771071 apbA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 2-dehydropantoate 2-reductase YP_001687.1 2113252 D 267671 CDS YP_001688.1 45657602 2770873 complement(2114536..2115723) 1 NC_005823.1 hypothetical protein 2115723 2770873 LIC11736 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001688.1 2114536 R 267671 CDS YP_001689.1 45657603 2771368 complement(2115725..2116522) 1 NC_005823.1 hypothetical protein 2116522 2771368 LIC11737 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001689.1 2115725 R 267671 CDS YP_001690.1 45657604 2771736 complement(2116575..2118704) 1 NC_005823.1 penicillin binding protein 2118704 pbp2 2771736 pbp2 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 penicillin binding protein YP_001690.1 2116575 R 267671 CDS YP_001691.1 45657605 2771121 complement(2118868..2124672) 1 NC_005823.1 hypothetical protein 2124672 2771121 LIC11739 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001691.1 2118868 R 267671 CDS YP_001692.1 45657606 2769792 complement(2124746..2126080) 1 NC_005823.1 hypothetical protein 2126080 pmbA 2769792 pmbA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001692.1 2124746 R 267671 CDS YP_001693.1 45657607 2772517 complement(2126077..2127462) 1 NC_005823.1 hypothetical protein 2127462 tldD 2772517 tldD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001693.1 2126077 R 267671 CDS YP_001694.1 45657608 2771491 complement(2127511..2127888) 1 NC_005823.1 hypothetical protein 2127888 2771491 LIC11742 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001694.1 2127511 R 267671 CDS YP_001695.1 45657609 2770665 2129481..2129900 1 NC_005823.1 hypothetical protein 2129900 2770665 LIC11743 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001695.1 2129481 D 267671 CDS YP_001696.1 45657610 2771558 2130007..2130285 1 NC_005823.1 hypothetical protein 2130285 2771558 LIC11744 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001696.1 2130007 D 267671 CDS YP_001697.1 45657611 2770206 2130507..2131607 1 NC_005823.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 2131607 recA 2770206 recA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 recombinase A YP_001697.1 2130507 D 267671 CDS YP_001698.1 45657612 2771378 2131858..2132874 1 NC_005823.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 2132874 argC 2771378 argC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 N-acetyl-gamma-glutamyl-phosphate reductase YP_001698.1 2131858 D 267671 CDS YP_001699.1 45657613 2772858 2132880..2134817 1 NC_005823.1 long-chain-fatty-acid CoA ligase 2134817 ydiD 2772858 ydiD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 long-chain-fatty-acid CoA ligase YP_001699.1 2132880 D 267671 CDS YP_001700.1 45657614 2770913 2134804..2135451 1 NC_005823.1 hypothetical protein 2135451 2770913 LIC11748 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001700.1 2134804 D 267671 CDS YP_001701.1 45657615 2769906 complement(2135434..2137215) 1 NC_005823.1 hypothetical protein 2137215 2769906 LIC11749 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001701.1 2135434 R 267671 CDS YP_001702.1 45657616 2771746 2137283..2137930 1 NC_005823.1 hypothetical protein 2137930 2771746 LIC11750 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001702.1 2137283 D 267671 CDS YP_001703.1 45657617 2771451 2137927..2138988 1 NC_005823.1 lipopolysaccharide core biosynthesis protein 2138988 rfaQ 2771451 rfaQ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipopolysaccharide core biosynthesis protein YP_001703.1 2137927 D 267671 CDS YP_001704.1 45657618 2772306 complement(2139426..2140736) 1 NC_005823.1 glycosyl transferase 2140736 2772306 LIC11752 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyl transferase YP_001704.1 2139426 R 267671 CDS YP_001705.1 45657619 2772227 2140856..2142175 1 NC_005823.1 exopolysaccharide production protein 2142175 2772227 LIC11753 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 exopolysaccharide production protein YP_001705.1 2140856 D 267671 CDS YP_001706.1 45657620 2772106 complement(2142315..2144096) 1 NC_005823.1 lipoprotein 2144096 2772106 LIC11754 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001706.1 2142315 R 267671 CDS YP_001707.1 45657621 2769597 complement(2145488..2148514) 1 NC_005823.1 hypothetical protein 2148514 2769597 LIC11755 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001707.1 2145488 R 267671 CDS YP_001708.1 45657622 2771957 complement(2148564..2150393) 1 NC_005823.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 2150393 uvrC 2771957 uvrC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 excinuclease ABC subunit C YP_001708.1 2148564 R 267671 CDS YP_001709.1 45657623 2771320 complement(2150919..2151386) 1 NC_005823.1 peptide chain release factor 2-like protein 2151386 prfH 2771320 prfH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peptide chain release factor 2-like protein YP_001709.1 2150919 R 267671 CDS YP_001710.1 45657624 2772573 complement(2151393..2151815) 1 NC_005823.1 acyl-CoA hydrolase 2151815 2772573 LIC11758 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyl-CoA hydrolase YP_001710.1 2151393 R 267671 CDS YP_001711.1 45657625 2772694 complement(2151822..2152520) 1 NC_005823.1 endonuclease III 2152520 nth 2772694 nth Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 endonuclease III YP_001711.1 2151822 R 267671 CDS YP_001712.1 45657626 2769820 complement(2152468..2152752) 1 NC_005823.1 required for 70S ribosome assembly; 50S ribosomal protein L28 2152752 rpmB 2769820 rpmB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L28 YP_001712.1 2152468 R 267671 CDS YP_001713.1 45657627 2770038 2152898..2153941 1 NC_005823.1 hypothetical protein 2153941 2770038 LIC11761 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001713.1 2152898 D 267671 CDS YP_001714.1 45657628 2770853 complement(2154719..2155102) 1 NC_005823.1 hypothetical protein 2155102 2770853 LIC11762 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001714.1 2154719 R 267671 CDS YP_001715.1 45657629 2771142 2155377..2155811 1 NC_005823.1 hypothetical protein 2155811 2771142 LIC11763 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001715.1 2155377 D 267671 CDS YP_001716.1 45657630 2770309 complement(2155938..2157044) 1 NC_005823.1 aspartate aminotransferase 2157044 2770309 LIC11764 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aspartate aminotransferase YP_001716.1 2155938 R 267671 CDS YP_001717.1 45657631 2770451 complement(2157044..2157409) 1 NC_005823.1 hypothetical protein 2157409 2770451 LIC11765 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001717.1 2157044 R 267671 CDS YP_001718.2 304570493 2771463 2157512..2159275 1 NC_005823.1 phosphomannomutase 2159275 manB 2771463 manB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphomannomutase YP_001718.2 2157512 D 267671 CDS YP_001719.1 45657633 2771509 2159272..2160492 1 NC_005823.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 2160492 argD 2771509 argD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetylornithine aminotransferase YP_001719.1 2159272 D 267671 CDS YP_001720.1 45657634 2771817 2160509..2161585 1 NC_005823.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 2161585 leuB 2771817 leuB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-isopropylmalate dehydrogenase YP_001720.1 2160509 D 267671 CDS YP_001721.1 45657635 2770548 2161602..2162009 1 NC_005823.1 response regulator 2162009 2770548 LIC11769 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_001721.1 2161602 D 267671 CDS YP_001722.1 45657636 2769496 complement(2162006..2162551) 1 NC_005823.1 hypothetical protein 2162551 2769496 LIC11770 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001722.1 2162006 R 267671 CDS YP_001723.1 45657637 2772272 complement(2162548..2163057) 1 NC_005823.1 hypothetical protein 2163057 2772272 LIC11771 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001723.1 2162548 R 267671 CDS YP_001724.1 45657638 2770391 complement(2163130..2163405) 1 NC_005823.1 hypothetical protein 2163405 2770391 LIC11772 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001724.1 2163130 R 267671 CDS YP_001725.1 45657639 2772407 2163491..2164147 1 NC_005823.1 N-(5'-phosphoribosyl)anthranilate isomerase 2164147 trpF 2772407 trpF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 N-(5'-phosphoribosyl)anthranilate isomerase YP_001725.1 2163491 D 267671 CDS YP_001726.1 45657640 2772230 2164144..2166690 1 NC_005823.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2166690 mutS 2772230 mutS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA mismatch repair protein MutS YP_001726.1 2164144 D 267671 CDS YP_001727.1 45657641 2772757 complement(2166673..2167554) 1 NC_005823.1 phosphoserine phosphatase 2167554 serB 2772757 serB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoserine phosphatase YP_001727.1 2166673 R 267671 CDS YP_001728.1 45657642 2771820 complement(2167562..2168308) 1 NC_005823.1 hypothetical protein 2168308 2771820 LIC11776 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001728.1 2167562 R 267671 CDS YP_003858665.1 304570510 9714933 complement(2168316..2168492) 1 NC_005823.1 hypothetical protein 2168492 9714933 LIC14003 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003858665.1 2168316 R 267671 CDS YP_001729.1 45657643 2772393 complement(2168865..2169971) 1 NC_005823.1 biotin synthase 2169971 bioB 2772393 bioB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 biotin synthase YP_001729.1 2168865 R 267671 CDS YP_001730.1 45657644 2772656 complement(2169961..2171262) 1 NC_005823.1 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 2171262 bioA 2772656 bioA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_001730.1 2169961 R 267671 CDS YP_001731.1 45657645 2771519 complement(2171259..2171924) 1 NC_005823.1 dethiobiotin synthetase 2171924 bioD 2771519 bioD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dethiobiotin synthetase YP_001731.1 2171259 R 267671 CDS YP_001732.1 45657646 2771466 complement(2171924..2173054) 1 NC_005823.1 8-amino-7-oxononanoate synthase 2173054 bioF 2771466 bioF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 8-amino-7-oxononanoate synthase YP_001732.1 2171924 R 267671 CDS YP_001733.2 161621774 2772594 complement(2173072..2174052) 1 NC_005823.1 catalyzes the oxidation of malate to oxaloacetate; malate dehydrogenase 2174052 mdh 2772594 mdh Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 malate dehydrogenase YP_001733.2 2173072 R 267671 CDS YP_001734.1 45657648 2772152 complement(2174079..2175125) 1 NC_005823.1 hypothetical protein 2175125 2772152 LIC11782 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001734.1 2174079 R 267671 CDS YP_001735.1 45657649 2770772 2175384..2175689 1 NC_005823.1 hypothetical protein 2175689 2770772 LIC11783 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001735.1 2175384 D 267671 CDS YP_001736.1 45657650 2771635 2175698..2176339 1 NC_005823.1 hypothetical protein 2176339 2771635 LIC11784 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001736.1 2175698 D 267671 CDS YP_001737.1 45657651 2772082 complement(2176526..2176750) 1 NC_005823.1 hypothetical protein 2176750 2772082 LIC11785 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001737.1 2176526 R 267671 CDS YP_001738.1 45657652 2769760 complement(2176817..2177779) 1 NC_005823.1 homoserine kinase 2177779 thrB 2769760 thrB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 homoserine kinase YP_001738.1 2176817 R 267671 CDS YP_001739.1 45657653 2769696 2177920..2179542 1 NC_005823.1 sodium:solute symporter 2179542 2769696 LIC11787 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sodium:solute symporter YP_001739.1 2177920 D 267671 CDS YP_001740.1 45657654 2769791 complement(2179499..2180332) 1 NC_005823.1 alpha/beta hydrolase 2180332 2769791 LIC11788 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alpha/beta hydrolase YP_001740.1 2179499 R 267671 CDS YP_001741.1 45657655 2769782 complement(2180320..2181246) 1 NC_005823.1 hypothetical protein 2181246 2769782 LIC11789 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001741.1 2180320 R 267671 CDS YP_001742.1 45657656 2769620 complement(2181250..2182464) 1 NC_005823.1 aspartate aminotransferase 2182464 aspC 2769620 aspC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aspartate aminotransferase YP_001742.1 2181250 R 267671 CDS YP_001743.1 45657657 2769502 complement(2182516..2184225) 1 NC_005823.1 ATP-dependent DNA helicase 2184225 recG 2769502 recG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent DNA helicase YP_001743.1 2182516 R 267671 CDS YP_001744.1 45657658 2769701 complement(2185232..2186137) 1 NC_005823.1 hypothetical protein 2186137 2769701 LIC11792 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001744.1 2185232 R 267671 CDS YP_001745.1 45657659 2772078 2186279..2187265 1 NC_005823.1 signal peptide peptidase; endopeptidase IV 2187265 sppA 2772078 sppA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 endopeptidase IV YP_001745.1 2186279 D 267671 CDS YP_001746.1 45657660 2772486 2187301..2188722 1 NC_005823.1 alginate O-acetyltransferase protein 2188722 2772486 LIC11794 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alginate O-acetyltransferase protein YP_001746.1 2187301 D 267671 CDS YP_001747.1 45657661 2770025 2188892..2189533 1 NC_005823.1 hypothetical protein 2189533 2770025 LIC11795 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001747.1 2188892 D 267671 CDS YP_001748.1 45657662 2771350 2189530..2190510 1 NC_005823.1 sigma factor regulatory protein 2190510 2771350 LIC11796 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sigma factor regulatory protein YP_001748.1 2189530 D 267671 CDS YP_001749.1 45657663 2770200 2190507..2190806 1 NC_005823.1 hypothetical protein 2190806 2770200 LIC11797 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001749.1 2190507 D 267671 CDS YP_001750.1 45657664 2772658 2190940..2192235 1 NC_005823.1 hypothetical protein 2192235 2772658 LIC11798 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001750.1 2190940 D 267671 CDS YP_001751.1 45657665 2770714 complement(2192229..2193719) 1 NC_005823.1 glycerol kinase 2193719 glpK 2770714 glpK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycerol kinase YP_001751.1 2192229 R 267671 CDS YP_001752.1 45657666 2770292 complement(2193789..2194745) 1 NC_005823.1 hypothetical protein 2194745 2770292 LIC11800 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001752.1 2193789 R 267671 CDS YP_001753.1 45657667 2769726 2194939..2195253 1 NC_005823.1 anti-sigma factor antagonist 2195253 2769726 LIC11801 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_001753.1 2194939 D 267671 CDS YP_001754.1 45657668 2771116 2196195..2197577 1 NC_005823.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 2197577 2771116 LIC11803 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dihydrolipoamide dehydrogenase YP_001754.1 2196195 D 267671 CDS YP_001755.1 45657669 2771228 2197596..2198513 1 NC_005823.1 ABC transporter ATP-binding protein 2198513 yadG 2771228 yadG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_001755.1 2197596 D 267671 CDS YP_001756.1 45657670 2771827 2198510..2199283 1 NC_005823.1 ABC transporter permease 2199283 yadH 2771827 yadH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter permease YP_001756.1 2198510 D 267671 CDS YP_001757.1 45657671 2771959 2199287..2199550 1 NC_005823.1 BolA-like protein 2199550 2771959 LIC11806 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 BolA-like protein YP_001757.1 2199287 D 267671 CDS YP_001758.1 45657672 2772509 complement(2199528..2199722) 1 NC_005823.1 hypothetical protein 2199722 2772509 LIC11807 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001758.1 2199528 R 267671 CDS YP_001759.1 45657673 2771682 2201469..2201720 1 NC_005823.1 BolA-like protein 2201720 bolA 2771682 bolA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 BolA-like protein YP_001759.1 2201469 D 267671 CDS YP_001760.1 45657674 2771163 2201717..2202040 1 NC_005823.1 glutaredoxin-related protein 2202040 2771163 LIC11809 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutaredoxin-related protein YP_001760.1 2201717 D 267671 CDS YP_001761.1 45657675 2772652 2202037..2202279 1 NC_005823.1 hypothetical protein 2202279 2772652 LIC11810 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001761.1 2202037 D 267671 CDS YP_001762.1 45657676 2771535 complement(2202276..2203307) 1 NC_005823.1 hypothetical protein 2203307 2771535 LIC11811 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001762.1 2202276 R 267671 CDS YP_001763.1 45657677 2772022 complement(2203295..2204857) 1 NC_005823.1 gamma-glutamylcysteine synthetase 2204857 gshA 2772022 gshA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 gamma-glutamylcysteine synthetase YP_001763.1 2203295 R 267671 CDS YP_001764.1 45657678 2769632 complement(2204854..2206587) 1 NC_005823.1 gamma-glutamyltranspeptidase 2206587 ggt 2769632 ggt Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 gamma-glutamyltranspeptidase YP_001764.1 2204854 R 267671 CDS YP_001765.1 45657679 2770571 complement(2206601..2208823) 1 NC_005823.1 ATP-dependent Clp protease ATP-binding subunit 2208823 clpA 2770571 clpA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent Clp protease ATP-binding subunit YP_001765.1 2206601 R 267671 CDS YP_001766.1 45657680 2770460 complement(2208838..2209173) 1 NC_005823.1 hypothetical protein 2209173 2770460 LIC11815 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001766.1 2208838 R 267671 CDS YP_001767.1 45657681 2769873 complement(2209170..2210390) 1 NC_005823.1 hypothetical protein 2210390 2769873 LIC11816 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001767.1 2209170 R 267671 CDS YP_001768.1 45657682 2770016 complement(2210424..2210978) 1 NC_005823.1 RNA polymerase ECF-type sigma factor 2210978 2770016 LIC11817 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA polymerase ECF-type sigma factor YP_001768.1 2210424 R 267671 CDS YP_001769.1 45657683 2770859 2211063..2211767 1 NC_005823.1 hypothetical protein 2211767 2770859 LIC11818 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001769.1 2211063 D 267671 CDS YP_001770.1 45657684 2770249 complement(2212588..2214492) 1 NC_005823.1 hypothetical protein 2214492 2770249 LIC11819 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001770.1 2212588 R 267671 CDS YP_001771.1 45657685 2772620 complement(2214489..2215490) 1 NC_005823.1 cysteine synthase 2215490 2772620 LIC11820 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cysteine synthase YP_001771.1 2214489 R 267671 CDS YP_001772.1 45657686 2771600 complement(2215506..2216126) 1 NC_005823.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 2216126 leuD 2771600 leuD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 isopropylmalate isomerase small subunit YP_001772.1 2215506 R 267671 CDS YP_001773.1 45657687 2769840 complement(2216146..2217543) 1 NC_005823.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 2217543 leuC 2769840 leuC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 isopropylmalate isomerase large subunit YP_001773.1 2216146 R 267671 CDS YP_001774.1 45657688 2771850 complement(2217701..2219164) 1 NC_005823.1 hypothetical protein 2219164 2771850 LIC11823 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001774.1 2217701 R 267671 CDS YP_001775.1 45657689 2771231 complement(2219161..2219922) 1 NC_005823.1 ABC transporter ATP-binding protein 2219922 oppD 2771231 oppD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_001775.1 2219161 R 267671 CDS YP_001776.1 45657690 2771223 complement(2219933..2220520) 1 NC_005823.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 2220520 gmhA 2771223 gmhA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoheptose isomerase YP_001776.1 2219933 R 267671 CDS YP_001777.1 45657691 2769563 complement(2220522..2221298) 1 NC_005823.1 hypothetical protein 2221298 2769563 LIC11826 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001777.1 2220522 R 267671 CDS YP_001778.1 45657692 2769640 complement(2221285..2222157) 1 NC_005823.1 lipopolysaccharide biosynthesis glycosyltransferase 2222157 2769640 LIC11827 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipopolysaccharide biosynthesis glycosyltransferase YP_001778.1 2221285 R 267671 CDS YP_001779.1 45657693 2771198 2225611..2226054 1 NC_005823.1 hypothetical protein 2226054 2771198 LIC11830 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001779.1 2225611 D 267671 CDS YP_001780.1 45657694 2771690 complement(2226964..2228775) 1 NC_005823.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 2228775 guaA 2771690 guaA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GMP synthase YP_001780.1 2226964 R 267671 CDS YP_001781.1 45657695 2769752 2228867..2229268 1 NC_005823.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 2229268 2769752 LIC11832 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 7-cyano-7-deazaguanine reductase YP_001781.1 2228867 D 267671 CDS YP_001782.1 45657696 2770439 2229286..2229576 1 NC_005823.1 hypothetical protein 2229576 2770439 LIC11833 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001782.1 2229286 D 267671 CDS YP_001783.1 45657697 2772492 complement(2229958..2230887) 1 NC_005823.1 lipoprotein 2230887 2772492 LIC11834 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001783.1 2229958 R 267671 CDS YP_001784.1 45657698 2770255 2231113..2231334 1 NC_005823.1 ferredoxin family protein 2231334 2770255 LIC11835 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ferredoxin family protein YP_001784.1 2231113 D 267671 CDS YP_001785.1 45657699 2770493 complement(2231806..2232831) 1 NC_005823.1 flagellar switch protein; with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2232831 fliM 2770493 fliM Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar motor switch protein FliM YP_001785.1 2231806 R 267671 CDS YP_001786.1 45657700 2769827 complement(2232828..2233805) 1 NC_005823.1 hypothetical protein 2233805 2769827 LIC11837 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001786.1 2232828 R 267671 CDS YP_001787.1 45657701 2772374 complement(2234380..2235003) 1 NC_005823.1 hypothetical protein 2235003 2772374 LIC11838 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001787.1 2234380 R 267671 CDS YP_001788.1 45657702 2770947 complement(2235000..2235875) 1 NC_005823.1 PPIase; peptidyl-prolyl cis-trans isomerase 2235875 ppiB 2770947 ppiB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peptidyl-prolyl cis-trans isomerase YP_001788.1 2235000 R 267671 CDS YP_001789.1 45657703 2772690 complement(2235872..2237284) 1 NC_005823.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 2237284 argH 2772690 argH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 argininosuccinate lyase YP_001789.1 2235872 R 267671 CDS YP_001790.1 45657704 2772221 complement(2237311..2237754) 1 NC_005823.1 hypothetical protein 2237754 2772221 LIC11841 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001790.1 2237311 R 267671 CDS YP_001791.1 45657705 2771688 2237730..2237930 1 NC_005823.1 hypothetical protein 2237930 2771688 LIC11842 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001791.1 2237730 D 267671 CDS YP_001792.1 45657706 2771111 2238149..2238328 1 NC_005823.1 hypothetical protein 2238328 2771111 LIC11843 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001792.1 2238149 D 267671 CDS YP_001793.1 45657707 2771953 2238360..2239307 1 NC_005823.1 hypothetical protein 2239307 2771953 LIC11844 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001793.1 2238360 D 267671 CDS YP_001794.1 45657708 2771540 2239309..2240241 1 NC_005823.1 internal repeat sequences detected; contains SPFH domain/Band 7 family as detected by pfam-hmmr; hypothetical protein 2240241 2771540 LIC11845 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001794.1 2239309 D 267671 CDS YP_001795.1 45657709 2771752 complement(2240718..2241254) 1 NC_005823.1 flagellar motor switch protein 2241254 2771752 LIC11846 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar motor switch protein YP_001795.1 2240718 R 267671 CDS YP_001796.1 45657710 2772073 2241351..2242637 1 NC_005823.1 ATPase AAA 2242637 2772073 LIC11847 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATPase AAA YP_001796.1 2241351 D 267671 CDS YP_001797.1 45657711 2771411 2242765..2243595 1 NC_005823.1 hypothetical protein 2243595 2771411 LIC11848 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001797.1 2242765 D 267671 CDS YP_001798.1 45657712 2771473 2243599..2244042 1 NC_005823.1 hypothetical protein 2244042 2771473 LIC11849 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001798.1 2243599 D 267671 CDS YP_001799.1 45657713 2771968 2244055..2244828 1 NC_005823.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 2244828 2771968 LIC11850 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 16S ribosomal RNA methyltransferase RsmE YP_001799.1 2244055 D 267671 CDS YP_001800.1 45657714 2771112 complement(2244825..2246468) 1 NC_005823.1 hypothetical protein 2246468 impL63 2771112 impL63 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001800.1 2244825 R 267671 CDS YP_001801.1 45657715 2770763 2246768..2248072 1 NC_005823.1 O-acetylhomoserine (thiol) lyase 2248072 2770763 LIC11852 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 O-acetylhomoserine (thiol) lyase YP_001801.1 2246768 D 267671 CDS YP_001802.1 45657716 2771068 2248331..2249431 1 NC_005823.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase 2249431 metX 2771068 metX Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 homoserine O-acetyltransferase YP_001802.1 2248331 D 267671 CDS YP_001803.1 45657717 2770874 2249435..2250052 1 NC_005823.1 methyltransferase 2250052 2770874 LIC11854 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methyltransferase YP_001803.1 2249435 D 267671 CDS YP_001804.1 45657718 2771229 complement(2250057..2251112) 1 NC_005823.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 2251112 ddlA 2771229 ddlA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 D-alanyl-alanine synthetase A YP_001804.1 2250057 R 267671 CDS YP_001805.1 45657719 2771279 2251203..2252522 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 2252522 2771279 LIC11856 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001805.1 2251203 D 267671 CDS YP_001806.1 45657720 2771537 2252519..2253298 1 NC_005823.1 ABC transporter permease 2253298 2771537 LIC11857 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter permease YP_001806.1 2252519 D 267671 CDS YP_001807.1 45657721 2771107 2253302..2254069 1 NC_005823.1 ABC transporter ATP-binding protein 2254069 2771107 LIC11858 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_001807.1 2253302 D 267671 CDS YP_001808.1 45657722 2771016 2254093..2254848 1 NC_005823.1 hypothetical protein 2254848 2771016 LIC11859 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001808.1 2254093 D 267671 CDS YP_001809.1 45657723 2770063 2254954..2255844 1 NC_005823.1 3-hydroxyisobutyrate dehydrogenase 2255844 mmsB 2770063 mmsB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-hydroxyisobutyrate dehydrogenase YP_001809.1 2254954 D 267671 CDS YP_001810.1 45657724 2771506 complement(2255804..2256352) 1 NC_005823.1 hypothetical protein 2256352 2771506 LIC11861 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001810.1 2255804 R 267671 CDS YP_001811.1 45657725 2771093 complement(2256349..2257548) 1 NC_005823.1 hypothetical protein 2257548 2771093 LIC11862 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001811.1 2256349 R 267671 CDS YP_001812.1 45657726 2771199 complement(2257649..2259121) 1 NC_005823.1 UDP-N-acetylmuramate-alanine ligase 2259121 murC 2771199 murC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-N-acetylmuramate-alanine ligase YP_001812.1 2257649 R 267671 CDS YP_001813.1 45657727 2771069 complement(2259118..2260194) 1 NC_005823.1 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase 2260194 murG 2771069 murG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase YP_001813.1 2259118 R 267671 CDS YP_001814.1 45657728 2771848 complement(2260191..2261345) 1 NC_005823.1 cell division protein 2261345 ftsW 2771848 ftsW Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cell division protein YP_001814.1 2260191 R 267671 CDS YP_001815.1 45657729 2770956 complement(2261342..2262448) 1 NC_005823.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 2262448 mraY 2770956 mraY Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_001815.1 2261342 R 267671 CDS YP_001816.1 45657730 2770780 complement(2262505..2264025) 1 NC_005823.1 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 2264025 murE 2770780 murE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_001816.1 2262505 R 267671 CDS YP_001817.1 45657731 2771983 complement(2263994..2264356) 1 NC_005823.1 hypothetical protein 2264356 2771983 LIC11868 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001817.1 2263994 R 267671 CDS YP_001818.1 45657732 2771393 complement(2264363..2265367) 1 NC_005823.1 S-adenosyl-methyltransferase 2265367 mraW 2771393 mraW Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 S-adenosyl-methyltransferase YP_001818.1 2264363 R 267671 CDS YP_001819.1 45657733 2770127 2265648..2266178 1 NC_005823.1 HIT family; identified by sequence similarity; ORF located using Blastx/Glimmer; hydrolase 2266178 2770127 LIC11870 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hydrolase YP_001819.1 2265648 D 267671 CDS YP_001820.1 45657734 2770187 complement(2266661..2267572) 1 NC_005823.1 chemotaxis protein methyltransferase 2267572 cheR 2770187 cheR Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chemotaxis protein methyltransferase YP_001820.1 2266661 R 267671 CDS YP_001821.1 45657735 2771349 2267722..2267997 1 NC_005823.1 hypothetical protein 2267997 2771349 LIC11872 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001821.1 2267722 D 267671 CDS YP_001822.1 45657736 2770036 2267994..2268743 1 NC_005823.1 hypothetical protein 2268743 2770036 LIC11873 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001822.1 2267994 D 267671 CDS YP_001823.1 45657737 2770330 complement(2269680..2270348) 1 NC_005823.1 hypothetical protein 2270348 2770330 LIC11874 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001823.1 2269680 R 267671 CDS YP_001824.1 45657738 2770374 complement(2270623..2271861) 1 NC_005823.1 hydrolase 2271861 2770374 LIC11875 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hydrolase YP_001824.1 2270623 R 267671 CDS YP_001825.1 45657739 2771944 2271845..2272381 1 NC_005823.1 hypothetical protein 2272381 2771944 LIC11876 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001825.1 2271845 D 267671 CDS YP_001826.1 45657740 2771322 complement(2272884..2273096) 1 NC_005823.1 hypothetical protein 2273096 2771322 LIC11877 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001826.1 2272884 R 267671 CDS YP_001827.1 45657741 2771842 2274255..2274722 1 NC_005823.1 hypothetical protein 2274722 2771842 LIC11878 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001827.1 2274255 D 267671 CDS YP_001828.1 45657742 2771703 complement(2275169..2275867) 1 NC_005823.1 hypothetical protein 2275867 2771703 LIC11879 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001828.1 2275169 R 267671 CDS YP_001829.1 45657743 2771450 complement(2275907..2276758) 1 NC_005823.1 lipoprotein 2276758 2771450 LIC11880 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001829.1 2275907 R 267671 CDS YP_001830.1 45657744 2771077 complement(2276977..2277723) 1 NC_005823.1 hypothetical protein 2277723 2771077 LIC11881 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001830.1 2276977 R 267671 CDS YP_001831.1 45657745 2772379 complement(2278039..2278890) 1 NC_005823.1 hypothetical protein 2278890 2772379 LIC11882 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001831.1 2278039 R 267671 CDS YP_001832.1 45657746 2772550 complement(2278887..2279549) 1 NC_005823.1 hypothetical protein 2279549 2772550 LIC11883 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001832.1 2278887 R 267671 CDS YP_001833.1 45657747 2772424 complement(2279518..2280816) 1 NC_005823.1 hypothetical protein 2280816 2772424 LIC11884 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001833.1 2279518 R 267671 CDS YP_001834.1 45657748 2771113 2280846..2282084 1 NC_005823.1 lipoprotein 2282084 2771113 LIC11885 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001834.1 2280846 D 267671 CDS YP_001835.1 45657749 2771609 2282735..2283301 1 NC_005823.1 lipoprotein 2283301 2771609 LIC11886 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001835.1 2282735 D 267671 CDS YP_001836.1 45657750 2771664 2283387..2283878 1 NC_005823.1 lipoprotein 2283878 2771664 LIC11887 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001836.1 2283387 D 267671 CDS YP_001837.1 45657751 2771425 complement(2284017..2285354) 1 NC_005823.1 hypothetical protein 2285354 2771425 LIC11888 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001837.1 2284017 R 267671 CDS YP_001838.1 45657752 2771544 complement(2286369..2287220) 1 NC_005823.1 flagellin protein 2287220 flaB 2771544 flaB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellin protein YP_001838.1 2286369 R 267671 CDS YP_001839.1 45657753 2772916 complement(2287676..2288521) 1 NC_005823.1 flagellin protein 2288521 2772916 LIC11890 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellin protein YP_001839.1 2287676 R 267671 CDS YP_001840.1 45657754 2771166 complement(2289309..2289683) 1 NC_005823.1 hypothetical protein 2289683 2771166 LIC11891 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001840.1 2289309 R 267671 CDS YP_001841.1 45657755 2771055 complement(2289674..2290144) 1 NC_005823.1 hypothetical protein 2290144 2771055 LIC11892 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001841.1 2289674 R 267671 CDS YP_001842.1 45657756 2772079 complement(2290323..2291669) 1 NC_005823.1 hypothetical protein 2291669 2772079 LIC11893 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001842.1 2290323 R 267671 CDS YP_001843.1 45657757 2771255 complement(2291687..2291902) 1 NC_005823.1 hypothetical protein 2291902 2771255 LIC11894 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001843.1 2291687 R 267671 CDS YP_001844.1 45657758 2771262 complement(2292172..2293497) 1 NC_005823.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 2293497 2771262 LIC11895 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sensory histidine kinase CreC YP_001844.1 2292172 R 267671 CDS YP_001845.1 45657759 2770545 complement(2293595..2294317) 1 NC_005823.1 response regulator 2294317 2770545 LIC11896 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_001845.1 2293595 R 267671 CDS YP_001846.1 45657760 2771554 2294415..2295398 1 NC_005823.1 pyruvate dehydrogenase alpha2 subunit protein 2295398 acoA 2771554 acoA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pyruvate dehydrogenase alpha2 subunit protein YP_001846.1 2294415 D 267671 CDS YP_001847.1 45657761 2771301 2295398..2296372 1 NC_005823.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acyltransferase within the complex. The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2); it contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta 2296372 acoB 2771301 acoB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pyruvate dehydrogenase subunit beta YP_001847.1 2295398 D 267671 CDS YP_001848.2 304570494 2770501 2297776..2298795 1 NC_005823.1 hypothetical protein 2298795 2770501 LIC11900 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001848.2 2297776 D 267671 CDS YP_001849.1 45657763 2772293 2299067..2299294 1 NC_005823.1 hypothetical protein 2299294 2772293 LIC11901 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001849.1 2299067 D 267671 CDS YP_001850.1 45657764 2771053 complement(2299384..2299662) 1 NC_005823.1 hypothetical protein 2299662 2771053 LIC11902 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001850.1 2299384 R 267671 CDS YP_001851.1 45657765 2770070 complement(2299937..2300797) 1 NC_005823.1 lipoprotein 2300797 2770070 LIC11903 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001851.1 2299937 R 267671 CDS YP_001852.1 45657766 2771512 complement(2300794..2302038) 1 NC_005823.1 hypothetical protein 2302038 2771512 LIC11904 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001852.1 2300794 R 267671 CDS YP_001853.1 45657767 2771214 2303688..2304362 1 NC_005823.1 phosphatidylglycerophosphate synthase-like protein 2304362 2771214 LIC11906 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphatidylglycerophosphate synthase-like protein YP_001853.1 2303688 D 267671 CDS YP_001854.1 45657768 2771292 2305031..2305282 1 NC_005823.1 hypothetical protein 2305282 2771292 LIC11908 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001854.1 2305031 D 267671 CDS YP_001855.1 45657769 2772946 2305267..2305737 1 NC_005823.1 hypothetical protein 2305737 2772946 LIC11909 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001855.1 2305267 D 267671 CDS YP_001856.1 45657770 2771750 2305758..2306660 1 NC_005823.1 polysaccharide deacetylase 2306660 2771750 LIC11910 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 polysaccharide deacetylase YP_001856.1 2305758 D 267671 CDS YP_001857.1 45657771 2772927 2306871..2309051 1 NC_005823.1 glycosyltransferase 2309051 2772927 LIC11911 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyltransferase YP_001857.1 2306871 D 267671 CDS YP_001858.1 45657772 2771429 2309101..2309751 1 NC_005823.1 hypothetical protein 2309751 2771429 LIC11912 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001858.1 2309101 D 267671 CDS YP_001859.1 45657773 2772044 2309760..2311247 1 NC_005823.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 2311247 lysS 2772044 lysS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lysyl-tRNA synthetase YP_001859.1 2309760 D 267671 CDS YP_001860.1 45657774 2771418 complement(2312284..2313111) 1 NC_005823.1 UDP-n-acetyl-d-mannosamine transferase 2313111 wecG 2771418 wecG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-n-acetyl-d-mannosamine transferase YP_001860.1 2312284 R 267671 CDS YP_001861.1 45657775 2771551 complement(2313166..2313810) 1 NC_005823.1 thiamine phosphate pyrophosphorylase 2313810 thiE 2771551 thiE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thiamine phosphate pyrophosphorylase YP_001861.1 2313166 R 267671 CDS YP_001862.1 45657776 2771319 2314386..2314670 1 NC_005823.1 lipoprotein 2314670 2771319 LIC11916 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001862.1 2314386 D 267671 CDS YP_001863.1 45657777 2772605 complement(2314660..2315352) 1 NC_005823.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 2315352 2772605 LIC11917 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 16S ribosomal RNA methyltransferase RsmE YP_001863.1 2314660 R 267671 CDS YP_001864.1 45657778 2769610 complement(2315362..2316144) 1 NC_005823.1 hypothetical protein 2316144 2769610 LIC11918 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001864.1 2315362 R 267671 CDS YP_001865.1 45657779 2769635 complement(2316145..2317671) 1 NC_005823.1 IMP dehydrogenase 2317671 guaB 2769635 guaB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 IMP dehydrogenase YP_001865.1 2316145 R 267671 CDS YP_001866.1 45657780 2769664 2317742..2318911 1 NC_005823.1 hypothetical protein 2318911 2769664 LIC11920 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001866.1 2317742 D 267671 CDS YP_001867.1 45657781 2769671 complement(2320123..2321397) 1 NC_005823.1 EAL domain; identified by sequence similarity; ORF located using Blastx/Glimmer; diguanylate phosphodiesterase 2321397 2769671 LIC11921 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 diguanylate phosphodiesterase YP_001867.1 2320123 R 267671 CDS YP_001868.1 45657782 2771310 2321379..2323196 1 NC_005823.1 hypothetical protein 2323196 2771310 LIC11922 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001868.1 2321379 D 267671 CDS YP_001869.1 45657783 2772572 2323973..2325292 1 NC_005823.1 hypothetical protein 2325292 2772572 LIC11923 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001869.1 2323973 D 267671 CDS YP_001870.1 45657784 2771455 2325296..2326918 1 NC_005823.1 hypothetical protein 2326918 2771455 LIC11924 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001870.1 2325296 D 267671 CDS YP_001871.1 45657785 2772263 complement(2327498..2328172) 1 NC_005823.1 hypothetical protein 2328172 2772263 LIC11925 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001871.1 2327498 R 267671 CDS YP_001872.1 45657786 2771008 complement(2328516..2329649) 1 NC_005823.1 glycosyltransferase; dolichol-P-glucose synthetase 2329649 mdoH 2771008 mdoH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dolichol-P-glucose synthetase YP_001872.1 2328516 R 267671 CDS YP_001873.1 45657787 2771401 complement(2329668..2331149) 1 NC_005823.1 hypothetical protein 2331149 2771401 LIC11927 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001873.1 2329668 R 267671 CDS YP_001874.1 45657788 2771738 complement(2331150..2332652) 1 NC_005823.1 FAD-binding oxidoreductase 2332652 2771738 LIC11928 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 FAD-binding oxidoreductase YP_001874.1 2331150 R 267671 CDS YP_001875.1 45657789 2771335 complement(2332671..2333447) 1 NC_005823.1 short-chain dehydrogenase 2333447 2771335 LIC11929 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 short-chain dehydrogenase YP_001875.1 2332671 R 267671 CDS YP_001876.1 45657790 2771726 complement(2333472..2334245) 1 NC_005823.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate; arginyl-tRNA-protein transferase 2334245 2771726 LIC11930 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 arginyl-tRNA-protein transferase YP_001876.1 2333472 R 267671 CDS YP_001877.1 45657791 2771033 2334629..2334946 1 NC_005823.1 hypothetical protein 2334946 2771033 LIC11931 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001877.1 2334629 D 267671 CDS YP_001878.1 45657792 2771098 2335678..2336079 1 NC_005823.1 hypothetical protein 2336079 2771098 LIC11933 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001878.1 2335678 D 267671 CDS YP_001879.1 45657793 2772913 2336072..2337370 1 NC_005823.1 polynucleotide adenyltransferase-like protein 2337370 2772913 LIC11934 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 polynucleotide adenyltransferase-like protein YP_001879.1 2336072 D 267671 CDS YP_001880.1 45657794 2772880 2338759..2340417 1 NC_005823.1 hypothetical protein 2340417 2772880 LIC11935 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001880.1 2338759 D 267671 CDS YP_001881.1 45657795 2772125 complement(2340447..2340641) 1 NC_005823.1 hypothetical protein 2340641 2772125 LIC11936 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001881.1 2340447 R 267671 CDS YP_001882.1 45657796 2771816 complement(2340958..2344278) 1 NC_005823.1 heavy metal efflux pump 2344278 czcA 2771816 czcA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heavy metal efflux pump YP_001882.1 2340958 R 267671 CDS YP_001883.1 45657797 2769813 complement(2344813..2348145) 1 NC_005823.1 heavy metal efflux pump 2348145 2769813 LIC11938 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heavy metal efflux pump YP_001883.1 2344813 R 267671 CDS YP_001884.1 45657798 2769828 complement(2348151..2348849) 1 NC_005823.1 hypothetical protein 2348849 2769828 LIC11939 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001884.1 2348151 R 267671 CDS YP_001885.1 45657799 2772287 complement(2348887..2349888) 1 NC_005823.1 heavy metal efflux pump 2349888 2772287 LIC11940 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heavy metal efflux pump YP_001885.1 2348887 R 267671 CDS YP_001886.1 45657800 2771638 complement(2349899..2351353) 1 NC_005823.1 heavy metal efflux pump 2351353 czcC 2771638 czcC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heavy metal efflux pump YP_001886.1 2349899 R 267671 CDS YP_001887.1 45657801 2771510 complement(2351453..2351830) 1 NC_005823.1 hypothetical protein 2351830 2771510 LIC11942 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001887.1 2351453 R 267671 CDS YP_001888.1 45657802 2771085 complement(2351931..2352368) 1 NC_005823.1 hypothetical protein 2352368 2771085 LIC11943 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001888.1 2351931 R 267671 CDS YP_001889.1 45657803 2771151 complement(2352392..2355124) 1 NC_005823.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 2355124 secA 2771151 secA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 preprotein translocase subunit SecA YP_001889.1 2352392 R 267671 CDS YP_001890.1 45657804 2771524 complement(2355229..2355978) 1 NC_005823.1 GMP synthase 2355978 2771524 LIC11945 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GMP synthase YP_001890.1 2355229 R 267671 CDS YP_001891.1 45657805 2772622 complement(2355975..2356646) 1 NC_005823.1 hypothetical protein 2356646 2772622 LIC11946 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001891.1 2355975 R 267671 CDS YP_001892.1 45657806 2771670 complement(2356810..2357385) 1 NC_005823.1 lipoprotein 2357385 2771670 LIC11947 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_001892.1 2356810 R 267671 CDS YP_001893.1 45657807 2769809 complement(2357360..2357917) 1 NC_005823.1 hypothetical protein 2357917 2769809 LIC11948 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001893.1 2357360 R 267671 CDS YP_001894.1 45657808 2769819 complement(2357928..2358938) 1 NC_005823.1 hypothetical protein 2358938 2769819 LIC11949 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001894.1 2357928 R 267671 CDS YP_001895.1 45657809 2772579 complement(2358962..2359318) 1 NC_005823.1 hypothetical protein 2359318 2772579 LIC11950 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001895.1 2358962 R 267671 CDS YP_001896.1 45657810 2771980 complement(2359332..2359925) 1 NC_005823.1 ATP-dependent Clp protease-like, proteolytic subunit 2359925 2771980 LIC11951 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent Clp protease-like, proteolytic subunit YP_001896.1 2359332 R 267671 CDS YP_001897.1 45657811 2772132 complement(2359936..2360436) 1 NC_005823.1 hypothetical protein 2360436 2772132 LIC11952 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001897.1 2359936 R 267671 CDS YP_001898.1 45657812 2770716 complement(2360418..2360612) 1 NC_005823.1 hypothetical protein 2360612 2770716 LIC11953 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001898.1 2360418 R 267671 CDS YP_001899.1 45657813 2771795 complement(2360699..2361997) 1 NC_005823.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 2361997 eno 2771795 eno Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphopyruvate hydratase YP_001899.1 2360699 R 267671 CDS YP_001900.1 45657814 2771865 2362667..2363227 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 2363227 2771865 LIC11955 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001900.1 2362667 D 267671 CDS YP_001901.1 45657815 2771991 2363671..2364603 1 NC_005823.1 hypothetical protein 2364603 2771991 LIC11956 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001901.1 2363671 D 267671 CDS YP_001902.1 45657816 2771936 2364674..2365162 1 NC_005823.1 response regulator 2365162 2771936 LIC11957 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_001902.1 2364674 D 267671 CDS YP_001903.1 45657817 2770962 2365179..2366387 1 NC_005823.1 ARM repeat-containing protein 2366387 2770962 LIC11958 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ARM repeat-containing protein YP_001903.1 2365179 D 267671 CDS YP_001904.1 45657818 2772494 2366392..2366901 1 NC_005823.1 hypothetical protein 2366901 2772494 LIC11959 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001904.1 2366392 D 267671 CDS YP_001905.1 45657819 2772796 2366885..2367451 1 NC_005823.1 hypothetical protein 2367451 2772796 LIC11960 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001905.1 2366885 D 267671 CDS YP_001906.1 45657820 2771390 2368610..2368954 1 NC_005823.1 hypothetical protein 2368954 2771390 LIC11964 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001906.1 2368610 D 267671 CDS YP_001907.1 45657821 2769797 2369276..2369698 1 NC_005823.1 hypothetical protein 2369698 2769797 LIC11965 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001907.1 2369276 D 267671 CDS YP_001908.1 45657822 2770049 2370480..2370857 1 NC_005823.1 hypothetical protein 2370857 2770049 LIC11966 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001908.1 2370480 D 267671 CDS YP_001909.1 45657823 2770106 2372686..2373153 1 NC_005823.1 hypothetical protein 2373153 2770106 LIC11969 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001909.1 2372686 D 267671 CDS YP_001910.1 45657824 2770589 2374499..2376370 1 NC_005823.1 hypothetical protein 2376370 2770589 LIC11970 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001910.1 2374499 D 267671 CDS YP_001911.1 45657825 2772536 2376430..2377002 1 NC_005823.1 hypothetical protein 2377002 2772536 LIC11971 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001911.1 2376430 D 267671 CDS YP_001912.1 45657826 2769720 2377046..2377447 1 NC_005823.1 hypothetical protein 2377447 2769720 LIC11972 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001912.1 2377046 D 267671 CDS YP_001913.1 45657827 2770146 2377490..2378827 1 NC_005823.1 tetracycline resistance protein 2378827 tetA 2770146 tetA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tetracycline resistance protein YP_001913.1 2377490 D 267671 CDS YP_001914.1 45657828 2771533 complement(2379952..2381034) 1 NC_005823.1 outer membrane protein 2381034 2771533 LIC11975 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 outer membrane protein YP_001914.1 2379952 R 267671 CDS YP_001915.1 45657829 2770449 complement(2381074..2382204) 1 NC_005823.1 acyl-CoA dehydrogenase 2382204 2770449 LIC11976 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyl-CoA dehydrogenase YP_001915.1 2381074 R 267671 CDS YP_001916.1 45657830 2769682 complement(2382222..2384381) 1 NC_005823.1 cyclic nucleotide binding protein 2384381 2769682 LIC11977 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cyclic nucleotide binding protein YP_001916.1 2382222 R 267671 CDS YP_001917.1 45657831 2772650 complement(2384404..2384718) 1 NC_005823.1 thioredoxin 2384718 trxA 2772650 trxA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thioredoxin YP_001917.1 2384404 R 267671 CDS YP_001918.1 45657832 2771184 complement(2384769..2385578) 1 NC_005823.1 hypothetical protein 2385578 2771184 LIC11979 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001918.1 2384769 R 267671 CDS YP_001919.1 45657833 2772893 2385967..2386239 1 NC_005823.1 sec-independent protein secretion pathway component 2386239 tatA 2772893 tatA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sec-independent protein secretion pathway component YP_001919.1 2385967 D 267671 CDS YP_001920.1 45657834 2772909 2386236..2387036 1 NC_005823.1 sec-independent protein translocase 2387036 tatC 2772909 tatC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sec-independent protein translocase YP_001920.1 2386236 D 267671 CDS YP_001921.1 45657835 2772933 2387038..2388132 1 NC_005823.1 hypothetical protein 2388132 2772933 LIC11982 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001921.1 2387038 D 267671 CDS YP_001922.1 45657836 2772114 complement(2389127..2389924) 1 NC_005823.1 internal repeat sequences detected; contains MORN repeat as detected by pfam-hmmr; hypothetical protein 2389924 2772114 LIC11983 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001922.1 2389127 R 267671 CDS YP_001923.1 45657837 2772751 2390223..2390423 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 2390423 2772751 LIC11984 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001923.1 2390223 D 267671 CDS YP_001924.1 45657838 2769719 complement(2390710..2390985) 1 NC_005823.1 RNA-binding protein 2390985 2769719 LIC11985 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA-binding protein YP_001924.1 2390710 R 267671 CDS YP_001925.1 45657839 2770629 2392461..2394056 1 NC_005823.1 hypothetical protein 2394056 2770629 LIC11986 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001925.1 2392461 D 267671 CDS YP_001926.1 45657840 2772489 complement(2394230..2394499) 1 NC_005823.1 hypothetical protein 2394499 2772489 LIC11987 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001926.1 2394230 R 267671 CDS YP_001927.1 45657841 2772069 complement(2394704..2395441) 1 NC_005823.1 hypothetical protein 2395441 2772069 LIC11988 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001927.1 2394704 R 267671 CDS YP_001928.1 45657842 2771126 complement(2395488..2396396) 1 NC_005823.1 hypothetical protein 2396396 2771126 LIC11989 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001928.1 2395488 R 267671 CDS YP_001929.1 45657843 2770196 2396550..2400149 1 NC_005823.1 contains TPR and novel repeat domains; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 2400149 2770196 LIC11990 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001929.1 2396550 D 267671 CDS YP_001930.1 45657844 2771693 complement(2400688..2401224) 1 NC_005823.1 transmembrane protein; identified by sequence similarity; ORF located using Blastx/Glimmer; outer membrane protein 2401224 2771693 LIC11991 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 outer membrane protein YP_001930.1 2400688 R 267671 CDS YP_001931.2 304570495 2771877 2401441..2402664 1 NC_005823.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 2402664 serA 2771877 serA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 D-3-phosphoglycerate dehydrogenase YP_001931.2 2401441 D 267671 CDS YP_001932.1 45657846 2771720 2402824..2403129 1 NC_005823.1 hypothetical protein 2403129 2771720 LIC11993 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001932.1 2402824 D 267671 CDS YP_001933.1 45657847 2771227 2403973..2404419 1 NC_005823.1 hypothetical protein 2404419 2771227 LIC11994 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001933.1 2403973 D 267671 CDS YP_001934.1 45657848 2769957 complement(2404804..2405019) 1 NC_005823.1 hypothetical protein 2405019 2769957 LIC11995 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001934.1 2404804 R 267671 CDS YP_001935.1 45657849 2770635 complement(2405104..2406441) 1 NC_005823.1 hypothetical protein 2406441 2770635 LIC11996 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001935.1 2405104 R 267671 CDS YP_001936.1 45657850 2771327 complement(2406451..2407299) 1 NC_005823.1 hypothetical protein 2407299 2771327 LIC11997 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001936.1 2406451 R 267671 CDS YP_001937.1 45657851 2771135 complement(2407627..2408502) 1 NC_005823.1 alpha/beta hydrolase fold family; identified by sequence similarity; ORF located using Blastx/Glimmer; hydrolase 2408502 2771135 LIC11998 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hydrolase YP_001937.1 2407627 R 267671 CDS YP_001938.1 45657852 2769878 complement(2408745..2409209) 1 NC_005823.1 hypothetical protein 2409209 2769878 LIC11999 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001938.1 2408745 R 267671 CDS YP_001939.1 45657853 2772812 complement(2409199..2410725) 1 NC_005823.1 hypothetical protein 2410725 2772812 LIC12000 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001939.1 2409199 R 267671 CDS YP_001940.1 45657854 2772000 2410998..2411678 1 NC_005823.1 succinate dehydrogenase cytochrome subunit B 2411678 sdhC 2772000 sdhC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 succinate dehydrogenase cytochrome subunit B YP_001940.1 2410998 D 267671 CDS YP_001941.1 45657855 2772012 2411697..2413610 1 NC_005823.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 2413610 sdhA 2772012 sdhA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 succinate dehydrogenase flavoprotein subunit YP_001941.1 2411697 D 267671 CDS YP_001942.1 45657856 2771230 2413610..2414341 1 NC_005823.1 catalyzes the reversible formation of fumarate and ubiquinol from succinate and ubiquinone; succinate dehydrogenase/fumarate reductase iron-sulfur subunit 2414341 sdhB 2771230 sdhB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 succinate dehydrogenase/fumarate reductase iron-sulfur subunit YP_001942.1 2413610 D 267671 CDS YP_001943.1 45657857 2771078 complement(2414539..2414769) 1 NC_005823.1 hypothetical protein 2414769 2771078 LIC12004 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001943.1 2414539 R 267671 CDS YP_001944.1 45657858 2770189 complement(2414744..2415193) 1 NC_005823.1 hypothetical protein 2415193 2770189 LIC12005 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001944.1 2414744 R 267671 CDS YP_001945.1 45657859 2771470 2415334..2416026 1 NC_005823.1 hypothetical protein 2416026 2771470 LIC12006 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001945.1 2415334 D 267671 CDS YP_001946.1 45657860 2771531 2416422..2416685 1 NC_005823.1 hypothetical protein 2416685 2771531 LIC12007 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001946.1 2416422 D 267671 CDS YP_001947.1 45657861 2771103 complement(2416786..2417511) 1 NC_005823.1 hypothetical protein 2417511 2771103 LIC12008 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001947.1 2416786 R 267671 CDS YP_001948.1 45657862 2770696 complement(2418403..2419344) 1 NC_005823.1 1-aminocyclopropane-1-carboxylate deaminase 2419344 2770696 LIC12009 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 1-aminocyclopropane-1-carboxylate deaminase YP_001948.1 2418403 R 267671 CDS YP_001949.1 45657863 2771494 complement(2419675..2421477) 1 NC_005823.1 elongation factor; binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 2421477 lepA 2771494 lepA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GTP-binding protein LepA YP_001949.1 2419675 R 267671 CDS YP_001950.1 45657864 2771546 complement(2421603..2422361) 1 NC_005823.1 hypothetical protein 2422361 2771546 LIC12011 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001950.1 2421603 R 267671 CDS YP_001951.1 45657865 2771034 complement(2422373..2422723) 1 NC_005823.1 anti-sigma factor antagonist 2422723 2771034 LIC12012 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_001951.1 2422373 R 267671 CDS YP_001952.1 45657866 2772412 2422729..2423391 1 NC_005823.1 hypothetical protein 2423391 2772412 LIC12013 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001952.1 2422729 D 267671 CDS YP_001953.1 45657867 2771160 2423388..2423741 1 NC_005823.1 hypothetical protein 2423741 2771160 LIC12014 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001953.1 2423388 D 267671 CDS YP_001954.1 45657868 2771148 2427612..2428019 1 NC_005823.1 internal repeat sequences detected; contains Helix-turn-helix domain as detected by pfam-hmmr; hypothetical protein 2428019 2771148 LIC12016 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001954.1 2427612 D 267671 CDS YP_001955.1 45657869 2772251 complement(2428166..2430748) 1 NC_005823.1 heat shock protein; ATP-dependent protease 2430748 clpB 2772251 clpB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent protease YP_001955.1 2428166 R 267671 CDS YP_001956.1 45657870 2772701 2431140..2432747 1 NC_005823.1 sodium-dependent transporter 2432747 2772701 LIC12018 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sodium-dependent transporter YP_001956.1 2431140 D 267671 CDS YP_001957.1 45657871 2769938 2432866..2434842 1 NC_005823.1 ATP-dependent helicase 2434842 yoaA 2769938 yoaA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent helicase YP_001957.1 2432866 D 267671 CDS YP_001958.1 45657872 2770068 2434877..2435740 1 NC_005823.1 hypothetical protein 2435740 2770068 LIC12020 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001958.1 2434877 D 267671 CDS YP_001959.1 45657873 2770503 2436799..2437329 1 NC_005823.1 hypothetical protein 2437329 2770503 LIC12021 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001959.1 2436799 D 267671 CDS YP_001960.1 45657874 2772738 complement(2437364..2438137) 1 NC_005823.1 hypothetical protein 2438137 2772738 LIC12022 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001960.1 2437364 R 267671 CDS YP_001961.1 45657875 2771435 complement(2438676..2439680) 1 NC_005823.1 internal repeat sequences detected; contains FTH domain as detected by pfam-hmmr; hypothetical protein 2439680 2771435 LIC12023 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001961.1 2438676 R 267671 CDS YP_001962.1 45657876 2771092 complement(2440956..2441747) 1 NC_005823.1 hypothetical protein 2441747 2771092 LIC12024 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001962.1 2440956 R 267671 CDS YP_001963.1 45657877 2771511 complement(2442147..2443454) 1 NC_005823.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 2443454 asnC 2771511 asnC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 asparaginyl-tRNA synthetase YP_001963.1 2442147 R 267671 CDS YP_001964.1 45657878 2771905 2443536..2444390 1 NC_005823.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 2444390 folD 2771905 folD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_001964.1 2443536 D 267671 CDS YP_001965.1 45657879 2771715 2444406..2445371 1 NC_005823.1 hypothetical protein 2445371 2771715 LIC12027 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001965.1 2444406 D 267671 CDS YP_001966.1 45657880 2771233 2445368..2446783 1 NC_005823.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 2446783 cysS 2771233 cysS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cysteinyl-tRNA synthetase YP_001966.1 2445368 D 267671 CDS YP_001967.1 45657881 2771382 2446873..2447535 1 NC_005823.1 tRNA/rRNA methyltransferase 2447535 2771382 LIC12029 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tRNA/rRNA methyltransferase YP_001967.1 2446873 D 267671 CDS YP_001968.1 45657882 2770280 2448327..2449457 1 NC_005823.1 hypothetical protein 2449457 2770280 LIC12030 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001968.1 2448327 D 267671 CDS YP_001969.1 45657883 2771496 complement(2449725..2451944) 1 NC_005823.1 histidine kinase sensor protein 2451944 2771496 LIC12031 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_001969.1 2449725 R 267671 CDS YP_001970.1 45657884 2769766 complement(2452348..2453793) 1 NC_005823.1 catalase 2453793 katE 2769766 katE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 catalase YP_001970.1 2452348 R 267671 CDS YP_001971.1 45657885 2771579 complement(2453793..2454338) 1 NC_005823.1 ankyrin 2454338 ankB 2771579 ankB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ankyrin YP_001971.1 2453793 R 267671 CDS YP_001972.1 45657886 2770690 2454821..2455258 1 NC_005823.1 Fur family transcriptional regulator 2455258 2770690 LIC12034 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Fur family transcriptional regulator YP_001972.1 2454821 D 267671 CDS YP_001973.1 45657887 2770989 2456309..2457172 1 NC_005823.1 hook protein 2457172 flhO 2770989 flhO Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hook protein YP_001973.1 2456309 D 267671 CDS YP_001974.1 45657888 2771138 complement(2457205..2458611) 1 NC_005823.1 hypothetical protein 2458611 2771138 LIC12036 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001974.1 2457205 R 267671 CDS YP_001975.1 45657889 2769798 complement(2460628..2461068) 1 NC_005823.1 hypothetical protein 2461068 2769798 LIC12040 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001975.1 2460628 R 267671 CDS YP_001976.1 45657890 2772443 complement(2461194..2462456) 1 NC_005823.1 hypothetical protein 2462456 2772443 LIC12041 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001976.1 2461194 R 267671 CDS YP_001977.1 45657891 2771114 complement(2462493..2463176) 1 NC_005823.1 hypothetical protein 2463176 2771114 LIC12042 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001977.1 2462493 R 267671 CDS YP_001978.1 45657892 2771384 complement(2463978..2464343) 1 NC_005823.1 hypothetical protein 2464343 2771384 LIC12043 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001978.1 2463978 R 267671 CDS YP_001979.1 45657893 2770285 complement(2464340..2464882) 1 NC_005823.1 hypothetical protein 2464882 2770285 LIC12044 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001979.1 2464340 R 267671 CDS YP_001980.1 45657894 2771456 complement(2465274..2465525) 1 NC_005823.1 hypothetical protein 2465525 2771456 LIC12045 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001980.1 2465274 R 267671 CDS YP_001981.1 45657895 2771695 complement(2465784..2466524) 1 NC_005823.1 hypothetical protein 2466524 2771695 LIC12046 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001981.1 2465784 R 267671 CDS YP_001982.1 45657896 2770254 complement(2466521..2474185) 1 NC_005823.1 rhs; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 2474185 2770254 LIC12047 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001982.1 2466521 R 267671 CDS YP_001983.1 45657897 2770469 complement(2474367..2478875) 1 NC_005823.1 hypothetical protein 2478875 2770469 LIC12048 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001983.1 2474367 R 267671 CDS YP_001984.1 45657898 2770462 2479593..2480417 1 NC_005823.1 hypothetical protein 2480417 2770462 LIC12049 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001984.1 2479593 D 267671 CDS YP_001985.1 45657899 2771102 2480537..2481712 1 NC_005823.1 internal repeat sequences detected; contains Kelch motif as detected by pfam-hmmr; hypothetical protein 2481712 2771102 LIC12050 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001985.1 2480537 D 267671 CDS YP_001986.1 45657900 2771465 complement(2482018..2485746) 1 NC_005823.1 hypothetical protein 2485746 2771465 LIC12051 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001986.1 2482018 R 267671 CDS YP_001987.1 45657901 2772754 2486324..2486788 1 NC_005823.1 hypothetical protein 2486788 2772754 LIC12052 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001987.1 2486324 D 267671 CDS YP_001988.1 45657902 2769963 2487595..2488140 1 NC_005823.1 hypothetical protein 2488140 2769963 LIC12053 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001988.1 2487595 D 267671 CDS YP_001989.1 45657903 2770746 2488124..2488459 1 NC_005823.1 hypothetical protein 2488459 2770746 LIC12054 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001989.1 2488124 D 267671 CDS YP_001990.1 45657904 2770214 2488589..2489470 1 NC_005823.1 hypothetical protein 2489470 2770214 LIC12055 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001990.1 2488589 D 267671 CDS YP_001991.1 45657905 2771596 complement(2489416..2490264) 1 NC_005823.1 IS1500 transposase 2490264 2771596 LIC12056 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 IS1500 transposase YP_001991.1 2489416 R 267671 CDS YP_001992.1 45657906 2770740 complement(2491480..2492595) 1 NC_005823.1 histidine kinase response regulator hybrid protein 2492595 2770740 LIC12058 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase response regulator hybrid protein YP_001992.1 2491480 R 267671 CDS YP_001993.1 45657907 2771220 complement(2492609..2493214) 1 NC_005823.1 response regulator 2493214 2771220 LIC12059 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_001993.1 2492609 R 267671 CDS YP_001994.1 45657908 2772168 complement(2493296..2496220) 1 NC_005823.1 histidine kinase response regulator hybrid protein 2496220 2772168 LIC12060 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase response regulator hybrid protein YP_001994.1 2493296 R 267671 CDS YP_001995.1 45657909 2771676 complement(2496223..2496804) 1 NC_005823.1 protein-glutamate methylesterase 2496804 2771676 LIC12061 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 protein-glutamate methylesterase YP_001995.1 2496223 R 267671 CDS YP_001996.1 45657910 2771295 complement(2496827..2497651) 1 NC_005823.1 chemotaxis protein 2497651 2771295 LIC12062 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chemotaxis protein YP_001996.1 2496827 R 267671 CDS YP_001997.1 45657911 2770990 2498457..2499206 1 NC_005823.1 acyltransferase 2499206 2770990 LIC12063 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyltransferase YP_001997.1 2498457 D 267671 CDS YP_001998.1 45657912 2770779 2499203..2500201 1 NC_005823.1 hypothetical protein 2500201 2770779 LIC12064 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001998.1 2499203 D 267671 CDS YP_001999.1 45657913 2771658 complement(2500518..2500883) 1 NC_005823.1 hypothetical protein 2500883 2771658 LIC12065 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_001999.1 2500518 R 267671 CDS YP_002000.1 45657914 2770890 2500970..2501446 1 NC_005823.1 MarR family transcriptional regulator 2501446 2770890 LIC12066 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 MarR family transcriptional regulator YP_002000.1 2500970 D 267671 CDS YP_002001.1 45657915 2772814 complement(2501511..2506127) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 2506127 2772814 LIC12067 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002001.1 2501511 R 267671 CDS YP_002002.1 45657916 2771089 complement(2506139..2506360) 1 NC_005823.1 hypothetical protein 2506360 2771089 LIC12068 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002002.1 2506139 R 267671 CDS YP_002003.1 45657917 2771340 complement(2506373..2507968) 1 NC_005823.1 hypothetical protein 2507968 mviN 2771340 mviN Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002003.1 2506373 R 267671 CDS YP_002004.1 45657918 2771986 complement(2507972..2508904) 1 NC_005823.1 hypothetical protein 2508904 2771986 LIC12070 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002004.1 2507972 R 267671 CDS YP_002005.1 45657919 2771821 complement(2508911..2510074) 1 NC_005823.1 hypothetical protein 2510074 2771821 LIC12071 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002005.1 2508911 R 267671 CDS YP_002006.1 45657920 2771759 complement(2510737..2511387) 1 NC_005823.1 lipoate protein ligase B 2511387 lipB 2771759 lipB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoate protein ligase B YP_002006.1 2510737 R 267671 CDS YP_002007.1 45657921 2771440 2511400..2511933 1 NC_005823.1 hypothetical protein 2511933 2771440 LIC12073 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002007.1 2511400 D 267671 CDS YP_002008.1 45657922 2771582 2511945..2512295 1 NC_005823.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 2512295 panD 2771582 panD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aspartate alpha-decarboxylase YP_002008.1 2511945 D 267671 CDS YP_002009.1 45657923 2771330 2512385..2513233 1 NC_005823.1 hypothetical protein 2513233 2771330 LIC12075 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002009.1 2512385 D 267671 CDS YP_002010.1 45657924 2771566 complement(2513704..2513967) 1 NC_005823.1 hypothetical protein 2513967 2771566 LIC12076 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002010.1 2513704 R 267671 CDS YP_002011.1 45657925 2771328 complement(2513951..2514256) 1 NC_005823.1 hypothetical protein 2514256 2771328 LIC12077 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002011.1 2513951 R 267671 CDS YP_002012.1 45657926 2770207 2514227..2515804 1 NC_005823.1 hypothetical protein 2515804 2770207 LIC12078 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002012.1 2514227 D 267671 CDS YP_002013.1 45657927 2770287 2515813..2516613 1 NC_005823.1 ABC transporter ATP-binding protein 2516613 2770287 LIC12079 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_002013.1 2515813 D 267671 CDS YP_002014.1 45657928 2771604 complement(2517693..2519534) 1 NC_005823.1 DNA topoisomerase I protein 2519534 topA 2771604 topA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA topoisomerase I protein YP_002014.1 2517693 R 267671 CDS YP_002015.1 45657929 2771171 complement(2520023..2520208) 1 NC_005823.1 hypothetical protein 2520208 2771171 LIC12081 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002015.1 2520023 R 267671 CDS YP_002016.1 45657930 2771298 complement(2521078..2522007) 1 NC_005823.1 cysteine synthase 2522007 cysK 2771298 cysK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cysteine synthase YP_002016.1 2521078 R 267671 CDS YP_002017.1 45657931 2769812 complement(2522315..2522482) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 2522482 2769812 LIC12083 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002017.1 2522315 R 267671 CDS YP_002018.1 45657932 2770105 complement(2522775..2523848) 1 NC_005823.1 hypothetical protein 2523848 2770105 LIC12084 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002018.1 2522775 R 267671 CDS YP_002019.1 45657933 2771186 complement(2524132..2524677) 1 NC_005823.1 carbonic anhydrase 2524677 paaY 2771186 paaY Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 carbonic anhydrase YP_002019.1 2524132 R 267671 CDS YP_002020.1 45657934 2770521 2524784..2525344 1 NC_005823.1 SPaseI; signal peptidase I 2525344 sipA 2770521 sipA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 signal peptidase I YP_002020.1 2524784 D 267671 CDS YP_002021.1 45657935 2771090 2525511..2526965 1 NC_005823.1 histidine kinase sensor protein 2526965 2771090 LIC12087 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_002021.1 2525511 D 267671 CDS YP_002022.1 45657936 2771245 2526970..2527392 1 NC_005823.1 response regulator 2527392 2771245 LIC12088 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_002022.1 2526970 D 267671 CDS YP_002023.1 45657937 2770529 complement(2527873..2528295) 1 NC_005823.1 hypothetical protein 2528295 2770529 LIC12089 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002023.1 2527873 R 267671 CDS YP_002024.1 45657938 2771458 2529145..2530152 1 NC_005823.1 glyceraldehyde-3-phosphate dehydrogenase 2530152 gapA 2771458 gapA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glyceraldehyde-3-phosphate dehydrogenase YP_002024.1 2529145 D 267671 CDS YP_002025.1 45657939 2769661 2530156..2531346 1 NC_005823.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 2531346 pgk 2769661 pgk Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoglycerate kinase YP_002025.1 2530156 D 267671 CDS YP_002026.1 45657940 2771125 complement(2531379..2531747) 1 NC_005823.1 hypothetical protein 2531747 2771125 LIC12092 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002026.1 2531379 R 267671 CDS YP_002027.1 45657941 2770618 complement(2532428..2533252) 1 NC_005823.1 hypothetical protein 2533252 2770618 LIC12093 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002027.1 2532428 R 267671 CDS YP_002028.1 45657942 2769544 2533875..2534627 1 NC_005823.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 2534627 tpiA 2769544 tpiA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 triosephosphate isomerase YP_002028.1 2533875 D 267671 CDS YP_002029.1 45657943 2772376 2534664..2535059 1 NC_005823.1 preprotein translocase subunit SecG 2535059 secG 2772376 secG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 preprotein translocase subunit SecG YP_002029.1 2534664 D 267671 CDS YP_002030.1 45657944 2769928 2535127..2535783 1 NC_005823.1 hypothetical protein 2535783 2769928 LIC12096 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002030.1 2535127 D 267671 CDS YP_002031.1 45657945 2769556 2535790..2536923 1 NC_005823.1 histidine kinase sensor protein 2536923 2769556 LIC12097 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_002031.1 2535790 D 267671 CDS YP_002032.1 45657946 2771797 2536923..2537915 1 NC_005823.1 response regulator 2537915 2771797 LIC12098 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_002032.1 2536923 D 267671 CDS YP_002033.1 45657947 2769514 2538473..2539903 1 NC_005823.1 internal repeat sequences detected; contains Beta-propeller repeat as detected by pfam-hmmr; hypothetical protein 2539903 2769514 LIC12099 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002033.1 2538473 D 267671 CDS YP_002034.1 45657948 2771652 complement(2540186..2541265) 1 NC_005823.1 hypothetical protein 2541265 2771652 LIC12100 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002034.1 2540186 R 267671 CDS YP_002035.1 45657949 2771294 complement(2541262..2542518) 1 NC_005823.1 competence/damage-inducible protein; hypothetical protein 2542518 2771294 LIC12101 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002035.1 2541262 R 267671 CDS YP_002036.1 45657950 2771269 complement(2542518..2544308) 1 NC_005823.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2544308 argS 2771269 argS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 arginyl-tRNA synthetase YP_002036.1 2542518 R 267671 CDS YP_002037.1 45657951 2770642 complement(2544275..2544694) 1 NC_005823.1 hypothetical protein 2544694 2770642 LIC12103 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002037.1 2544275 R 267671 CDS YP_002038.1 45657952 2769750 complement(2544910..2545692) 1 NC_005823.1 DNA repair protein; hypothetical protein 2545692 recO 2769750 recO Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002038.1 2544910 R 267671 CDS YP_002039.1 45657953 2770423 complement(2545665..2546090) 1 NC_005823.1 hypothetical protein 2546090 2770423 LIC12105 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002039.1 2545665 R 267671 CDS YP_002040.1 45657954 2772654 complement(2546159..2548573) 1 NC_005823.1 hypothetical protein 2548573 2772654 LIC12106 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002040.1 2546159 R 267671 CDS YP_002041.1 45657955 2771202 complement(2548578..2549459) 1 NC_005823.1 phosphate starvation-inducible protein 2549459 2771202 LIC12107 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphate starvation-inducible protein YP_002041.1 2548578 R 267671 CDS YP_002042.1 45657956 2772327 complement(2549569..2551374) 1 NC_005823.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 2551374 aspS 2772327 aspS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aspartyl-tRNA synthetase YP_002042.1 2549569 R 267671 CDS YP_002043.1 45657957 2770359 complement(2551407..2552735) 1 NC_005823.1 replicative DNA helicase 2552735 dnaB 2770359 dnaB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 replicative DNA helicase YP_002043.1 2551407 R 267671 CDS YP_002044.1 45657958 2771846 complement(2552753..2553202) 1 NC_005823.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 2553202 rplI 2771846 rplI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L9 YP_002044.1 2552753 R 267671 CDS YP_002045.2 304570496 2771215 complement(2553212..2553523) 1 NC_005823.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 2553523 rpsR 2771215 rpsR Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S18 YP_002045.2 2553212 R 267671 CDS YP_002046.1 45657960 2770975 complement(2553535..2553987) 1 NC_005823.1 single-stranded DNA binding protein 2553987 ssb 2770975 ssb Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 single-stranded DNA binding protein YP_002046.1 2553535 R 267671 CDS YP_002047.1 45657961 2771333 complement(2553980..2554255) 1 NC_005823.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 2554255 rpsF 2771333 rpsF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S6 YP_002047.1 2553980 R 267671 CDS YP_002048.1 45657962 2771238 complement(2554320..2555549) 1 NC_005823.1 lipoprotein 2555549 2771238 LIC12114 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002048.1 2554320 R 267671 CDS YP_002049.1 45657963 2772448 complement(2555930..2557882) 1 NC_005823.1 ankyrin 2557882 2772448 LIC12115 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ankyrin YP_002049.1 2555930 R 267671 CDS YP_002050.1 45657964 2769920 complement(2558167..2558601) 1 NC_005823.1 hypothetical protein 2558601 2769920 LIC12116 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002050.1 2558167 R 267671 CDS YP_002051.1 45657965 2771659 complement(2558602..2558901) 1 NC_005823.1 hypothetical protein 2558901 2771659 LIC12117 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002051.1 2558602 R 267671 CDS YP_002052.1 45657966 2770799 complement(2559991..2561385) 1 NC_005823.1 DASS family; identified by sequence similarity; ORF located using Blastx/Glimmer; divalent anion Na+ symporter 2561385 2770799 LIC12118 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 divalent anion Na+ symporter YP_002052.1 2559991 R 267671 CDS YP_002053.1 45657967 2772769 complement(2561426..2562133) 1 NC_005823.1 glycosyl transferase 2562133 2772769 LIC12119 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyl transferase YP_002053.1 2561426 R 267671 CDS YP_002054.1 45657968 2770128 2562183..2562401 1 NC_005823.1 hypothetical protein 2562401 2770128 LIC12120 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002054.1 2562183 D 267671 CDS YP_002055.1 45657969 2771356 complement(2562832..2563743) 1 NC_005823.1 dTDP-rhamnosyl transferase 2563743 rfbF 2771356 rfbF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dTDP-rhamnosyl transferase YP_002055.1 2562832 R 267671 CDS YP_002056.1 45657970 2771515 complement(2563748..2564722) 1 NC_005823.1 glycosyltransferase 2564722 2771515 LIC12122 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyltransferase YP_002056.1 2563748 R 267671 CDS YP_002057.1 45657971 2771920 complement(2565703..2566587) 1 NC_005823.1 glucose-1-phosphate thymidylyltransferase 2566587 rfbA 2771920 rfbA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glucose-1-phosphate thymidylyltransferase YP_002057.1 2565703 R 267671 CDS YP_002058.1 45657972 2771179 complement(2566588..2567637) 1 NC_005823.1 dTDP-glucose 4,6-dehydratase 2567637 rfbB 2771179 rfbB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dTDP-glucose 4,6-dehydratase YP_002058.1 2566588 R 267671 CDS YP_002059.1 45657973 2771285 complement(2567634..2568554) 1 NC_005823.1 dTDP-4-dehydrorhamnose reductase 2568554 rfbD 2771285 rfbD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dTDP-4-dehydrorhamnose reductase YP_002059.1 2567634 R 267671 CDS YP_002060.1 45657974 2772371 complement(2568558..2569118) 1 NC_005823.1 dTDP-4-dehydrorhamnose 3,5-epimerase 2569118 rfbC 2772371 rfbC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dTDP-4-dehydrorhamnose 3,5-epimerase YP_002060.1 2568558 R 267671 CDS YP_002061.1 45657975 2771753 complement(2569315..2571063) 1 NC_005823.1 glycosyl transferase 2571063 2771753 LIC12127 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyl transferase YP_002061.1 2569315 R 267671 CDS YP_002062.1 45657976 2771273 complement(2571788..2572609) 1 NC_005823.1 glycosyl transferase 2572609 2771273 LIC12128 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyl transferase YP_002062.1 2571788 R 267671 CDS YP_002063.1 45657977 2772461 complement(2573119..2573916) 1 NC_005823.1 glycosyltransferase 2573916 2772461 LIC12129 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyltransferase YP_002063.1 2573119 R 267671 CDS YP_002064.1 45657978 2771453 complement(2574059..2575150) 1 NC_005823.1 degT family; identified by sequence similarity; ORF located using Blastx/Glimmer; aminotransferase 2575150 2771453 LIC12130 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aminotransferase YP_002064.1 2574059 R 267671 CDS YP_002065.1 45657979 2771796 complement(2575164..2575583) 1 NC_005823.1 hypothetical protein 2575583 2771796 LIC12131 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002065.1 2575164 R 267671 CDS YP_002066.1 45657980 2771282 complement(2575733..2576755) 1 NC_005823.1 glycosyltransferase 2576755 2771282 LIC12132 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyltransferase YP_002066.1 2575733 R 267671 CDS YP_002067.1 45657981 2771798 complement(2577396..2578289) 1 NC_005823.1 hypothetical protein 2578289 2771798 LIC12133 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002067.1 2577396 R 267671 CDS YP_002068.1 45657982 2771437 complement(2578989..2579930) 1 NC_005823.1 sugar transferase 2579930 hlpA 2771437 hlpA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sugar transferase YP_002068.1 2578989 R 267671 CDS YP_002069.1 45657983 2769833 complement(2579934..2581277) 1 NC_005823.1 polysaccharide biosynthesis export protein 2581277 2769833 LIC12135 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 polysaccharide biosynthesis export protein YP_002069.1 2579934 R 267671 CDS YP_002070.1 45657984 2770743 complement(2581601..2582869) 1 NC_005823.1 hypothetical protein 2582869 2770743 LIC12136 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002070.1 2581601 R 267671 CDS YP_002071.1 45657985 2772217 complement(2582919..2584184) 1 NC_005823.1 UDP-glucose lipid carrier transferase 2584184 2772217 LIC12137 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-glucose lipid carrier transferase YP_002071.1 2582919 R 267671 CDS YP_002072.1 45657986 2771459 complement(2584188..2585375) 1 NC_005823.1 colanic acid biosynthesis glycosyl-transferase 2585375 wcaI 2771459 wcaI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 colanic acid biosynthesis glycosyl-transferase YP_002072.1 2584188 R 267671 CDS YP_002073.1 45657987 2771492 complement(2585385..2586515) 1 NC_005823.1 UDP-N-acetylglucosamine 2-epimerase 2586515 rffE 2771492 rffE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-N-acetylglucosamine 2-epimerase YP_002073.1 2585385 R 267671 CDS YP_002074.1 45657988 2771599 complement(2586519..2587619) 1 NC_005823.1 nucleoside-diphosphate-sugar epimerase 2587619 2771599 LIC12140 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 nucleoside-diphosphate-sugar epimerase YP_002074.1 2586519 R 267671 CDS YP_002075.1 45657989 2771366 complement(2587626..2588660) 1 NC_005823.1 UDP-glucose 4-epimerase 2588660 2771366 LIC12141 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-glucose 4-epimerase YP_002075.1 2587626 R 267671 CDS YP_002076.1 45657990 2771996 complement(2589178..2590323) 1 NC_005823.1 glycosyl transferase 2590323 2771996 LIC12142 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyl transferase YP_002076.1 2589178 R 267671 CDS YP_002077.1 45657991 2769984 complement(2590413..2591702) 1 NC_005823.1 integral membrane protein 2591702 2769984 LIC12143 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 integral membrane protein YP_002077.1 2590413 R 267671 CDS YP_002078.1 45657992 2771872 complement(2591907..2593928) 1 NC_005823.1 integral membrane protein 2593928 2771872 LIC12144 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 integral membrane protein YP_002078.1 2591907 R 267671 CDS YP_002079.1 45657993 2769974 complement(2593916..2596045) 1 NC_005823.1 glycosyltransferase 2596045 2769974 LIC12145 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyltransferase YP_002079.1 2593916 R 267671 CDS YP_002080.1 45657994 2770523 complement(2596030..2596893) 1 NC_005823.1 polysaccharide deacetylase family protein 2596893 2770523 LIC12146 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 polysaccharide deacetylase family protein YP_002080.1 2596030 R 267671 CDS YP_002081.1 45657995 2771598 complement(2596904..2597272) 1 NC_005823.1 hypothetical protein 2597272 2771598 LIC12147 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002081.1 2596904 R 267671 CDS YP_002082.1 45657996 2771840 complement(2597742..2598638) 1 NC_005823.1 glycosyltransferase 2598638 2771840 LIC12148 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyltransferase YP_002082.1 2597742 R 267671 CDS YP_002083.1 45657997 2772834 complement(2598646..2599608) 1 NC_005823.1 UDP-glucose 4-epimerase 2599608 galE 2772834 galE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-glucose 4-epimerase YP_002083.1 2598646 R 267671 CDS YP_002084.1 45657998 2771352 complement(2599599..2600066) 1 NC_005823.1 dTDP-4-dehydrorhamnose epimerase 2600066 2771352 LIC12150 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dTDP-4-dehydrorhamnose epimerase YP_002084.1 2599599 R 267671 CDS YP_002085.1 45657999 2771158 complement(2600054..2601145) 1 NC_005823.1 CDP-glucose 4,6-dehydratase 2601145 rfbG 2771158 rfbG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 CDP-glucose 4,6-dehydratase YP_002085.1 2600054 R 267671 CDS YP_002086.1 45658000 2769789 complement(2601148..2601915) 1 NC_005823.1 glucose-1-phosphate cytidylyltransferase 2601915 2769789 LIC12152 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glucose-1-phosphate cytidylyltransferase YP_002086.1 2601148 R 267671 CDS YP_002087.1 45658001 2772421 complement(2601926..2603545) 1 NC_005823.1 hypothetical protein 2603545 2772421 LIC13510 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002087.1 2601926 R 267671 CDS YP_002088.1 45658002 2771644 complement(2603811..2604809) 1 NC_005823.1 D-3-phosphoglycerate dehydrogenase 2604809 2771644 LIC12153 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 D-3-phosphoglycerate dehydrogenase YP_002088.1 2603811 R 267671 CDS YP_002089.1 45658003 2769778 complement(2604853..2605815) 1 NC_005823.1 3-demethylubiquinone-9 3-methyltransferase 2605815 2769778 LIC12154 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-demethylubiquinone-9 3-methyltransferase YP_002089.1 2604853 R 267671 CDS YP_002090.1 45658004 2769784 complement(2606023..2606796) 1 NC_005823.1 inositol monophosphatase 2606796 2769784 LIC12155 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 inositol monophosphatase YP_002090.1 2606023 R 267671 CDS YP_002091.1 45658005 2769574 complement(2606809..2607837) 1 NC_005823.1 oxidoreductase family protein 2607837 2769574 LIC12156 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 oxidoreductase family protein YP_002091.1 2606809 R 267671 CDS YP_002092.1 45658006 2769535 complement(2607840..2608595) 1 NC_005823.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 2608595 2769535 LIC12157 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-deoxy-manno-octulosonate cytidylyltransferase YP_002092.1 2607840 R 267671 CDS YP_002093.1 45658007 2769526 complement(2608630..2609385) 1 NC_005823.1 hydroxyacid aldolase 2609385 2769526 LIC12158 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hydroxyacid aldolase YP_002093.1 2608630 R 267671 CDS YP_002094.1 45658008 2770678 complement(2609534..2609806) 1 NC_005823.1 hypothetical protein 2609806 2770678 LIC12159 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002094.1 2609534 R 267671 CDS YP_002095.1 45658009 2769934 complement(2610083..2610358) 1 NC_005823.1 hypothetical protein 2610358 2769934 LIC12160 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002095.1 2610083 R 267671 CDS YP_002096.1 45658010 2770955 complement(2610410..2611069) 1 NC_005823.1 6-phosphogluconolactonase/glucosamine-6- phosphate isomerase/deaminase 2611069 nagB 2770955 nagB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 6-phosphogluconolactonase/glucosamine-6- phosphate isomerase/deaminase YP_002096.1 2610410 R 267671 CDS YP_002097.1 45658011 2772554 complement(2611182..2612948) 1 NC_005823.1 hypothetical protein 2612948 2772554 LIC12162 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002097.1 2611182 R 267671 CDS YP_002098.1 45658012 2772405 complement(2613060..2614868) 1 NC_005823.1 hypothetical protein 2614868 2772405 LIC12163 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002098.1 2613060 R 267671 CDS YP_002099.1 45658013 2769866 complement(2615181..2616044) 1 NC_005823.1 hypothetical protein 2616044 2769866 LIC12164 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002099.1 2615181 R 267671 CDS YP_002100.1 45658014 2772484 complement(2616308..2617285) 1 NC_005823.1 molybdenum cofactor biosynthesis protein 2617285 moaA 2772484 moaA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 molybdenum cofactor biosynthesis protein YP_002100.1 2616308 R 267671 CDS YP_002101.1 45658015 2770044 complement(2617286..2618353) 1 NC_005823.1 alcohol dehydrogenase 2618353 2770044 LIC12166 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alcohol dehydrogenase YP_002101.1 2617286 R 267671 CDS YP_002102.1 45658016 2770832 complement(2618427..2619056) 1 NC_005823.1 CMP-N-acetlyneuraminic acid synthetase 2619056 2770832 LIC12167 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 CMP-N-acetlyneuraminic acid synthetase YP_002102.1 2618427 R 267671 CDS YP_002103.1 45658017 2770286 complement(2619061..2620245) 1 NC_005823.1 aspartate aminotransferase 2620245 2770286 LIC12168 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aspartate aminotransferase YP_002103.1 2619061 R 267671 CDS YP_002104.1 45658018 2772495 complement(2620267..2622528) 1 NC_005823.1 sialic acid synthase 2622528 sas 2772495 sas Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sialic acid synthase YP_002104.1 2620267 R 267671 CDS YP_002105.1 45658019 2770663 complement(2622555..2623703) 1 NC_005823.1 hypothetical protein 2623703 2770663 LIC12170 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002105.1 2622555 R 267671 CDS YP_002106.1 45658020 2769859 complement(2624077..2625132) 1 NC_005823.1 nucleoside-diphosphate-sugar pyrophosphorylase 2625132 2769859 LIC12171 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 nucleoside-diphosphate-sugar pyrophosphorylase YP_002106.1 2624077 R 267671 CDS YP_002107.1 45658021 2771043 complement(2625381..2626544) 1 NC_005823.1 UDP-N-acetylglucosamine-2-epimerase 2626544 2771043 LIC12172 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-N-acetylglucosamine-2-epimerase YP_002107.1 2625381 R 267671 CDS YP_002108.1 45658022 2771414 complement(2626541..2627575) 1 NC_005823.1 N-acetylneuraminate synthase 2627575 neuB 2771414 neuB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 N-acetylneuraminate synthase YP_002108.1 2626541 R 267671 CDS YP_002109.1 45658023 2770903 complement(2627553..2628188) 1 NC_005823.1 acetyl transferase 2628188 2770903 LIC12174 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyl transferase YP_002109.1 2627553 R 267671 CDS YP_002110.1 45658024 2771025 complement(2628166..2629329) 1 NC_005823.1 degT family; identified by sequence similarity; ORF located using Blastx/Glimmer; aminotransferase 2629329 2771025 LIC12175 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aminotransferase YP_002110.1 2628166 R 267671 CDS YP_002111.1 45658025 2771217 complement(2629329..2630321) 1 NC_005823.1 UDP-glucose 4-epimerase 2630321 2771217 LIC12176 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-glucose 4-epimerase YP_002111.1 2629329 R 267671 CDS YP_002112.1 45658026 2771133 complement(2630324..2631010) 1 NC_005823.1 CMP-N-acetlyneuraminic acid synthetase 2631010 neuA 2771133 neuA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 CMP-N-acetlyneuraminic acid synthetase YP_002112.1 2630324 R 267671 CDS YP_002113.1 45658027 2770725 complement(2631184..2632836) 1 NC_005823.1 hypothetical protein 2632836 2770725 LIC12178 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002113.1 2631184 R 267671 CDS YP_002114.1 45658028 2770715 complement(2633014..2633961) 1 NC_005823.1 sugar transferase 2633961 2770715 LIC12179 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sugar transferase YP_002114.1 2633014 R 267671 CDS YP_002115.1 45658029 2771110 complement(2633963..2634697) 1 NC_005823.1 methyltransferase 2634697 2771110 LIC12180 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methyltransferase YP_002115.1 2633963 R 267671 CDS YP_002116.1 45658030 2770474 complement(2634690..2635118) 1 NC_005823.1 unknown protein LPS related rfb locus of L. borgpetersenii; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 2635118 2770474 LIC12181 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002116.1 2634690 R 267671 CDS YP_002117.1 45658031 2772165 complement(2635253..2637070) 1 NC_005823.1 ABC transporter ATP-binding protein 2637070 2772165 LIC12182 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_002117.1 2635253 R 267671 CDS YP_002118.1 45658032 2770611 complement(2637198..2638451) 1 NC_005823.1 hypothetical protein 2638451 2770611 LIC12183 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002118.1 2637198 R 267671 CDS YP_002119.1 45658033 2770032 complement(2638448..2638963) 1 NC_005823.1 acetyl transferase 2638963 2770032 LIC12184 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyl transferase YP_002119.1 2638448 R 267671 CDS YP_002120.1 45658034 2770637 complement(2639111..2639410) 1 NC_005823.1 fucose synthetase 2639410 fcI 2770637 fcI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 fucose synthetase YP_002120.1 2639111 R 267671 CDS YP_002121.1 45658035 2770256 complement(2639681..2640607) 1 NC_005823.1 methionyl-tRNA(fmet) n-formyltransferase 2640607 2770256 LIC12186 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methionyl-tRNA(fmet) n-formyltransferase YP_002121.1 2639681 R 267671 CDS YP_002122.1 45658036 2772558 complement(2640600..2641676) 1 NC_005823.1 perosamine synthetase 2641676 per 2772558 per Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 perosamine synthetase YP_002122.1 2640600 R 267671 CDS YP_002123.1 45658037 2769724 complement(2641678..2642895) 1 NC_005823.1 hypothetical protein 2642895 2769724 LIC12188 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002123.1 2641678 R 267671 CDS YP_002124.1 45658038 2769589 complement(2642892..2643419) 1 NC_005823.1 hypothetical protein 2643419 2769589 LIC12189 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002124.1 2642892 R 267671 CDS YP_002125.1 45658039 2769577 complement(2643960..2644535) 1 NC_005823.1 SAM-dependent methyltransferase 2644535 2769577 LIC12190 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 SAM-dependent methyltransferase YP_002125.1 2643960 R 267671 CDS YP_002126.1 45658040 2770291 complement(2644632..2645066) 1 NC_005823.1 mutator protein 2645066 mutT 2770291 mutT Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 mutator protein YP_002126.1 2644632 R 267671 CDS YP_002127.1 45658041 2769576 complement(2645070..2645465) 1 NC_005823.1 hypothetical protein 2645465 2769576 LIC12192 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002127.1 2645070 R 267671 CDS YP_002128.1 45658042 2770118 complement(2645462..2646256) 1 NC_005823.1 hypothetical protein 2646256 2770118 LIC12193 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002128.1 2645462 R 267671 CDS YP_002129.1 45658043 2771076 complement(2646629..2647561) 1 NC_005823.1 transketolase subunit beta 2647561 tktC 2771076 tktC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transketolase subunit beta YP_002129.1 2646629 R 267671 CDS YP_002130.1 45658044 2772825 complement(2647580..2648377) 1 NC_005823.1 transketolase 2648377 2772825 LIC12195 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transketolase YP_002130.1 2647580 R 267671 CDS YP_002131.1 45658045 2769651 complement(2648384..2650018) 1 NC_005823.1 hypothetical protein 2650018 2769651 LIC12196 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002131.1 2648384 R 267671 CDS YP_002132.1 45658046 2770459 complement(2650019..2651122) 1 NC_005823.1 degT family; identified by sequence similarity; ORF located using Blastx/Glimmer; aminotransferase 2651122 2770459 LIC12197 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aminotransferase YP_002132.1 2650019 R 267671 CDS YP_002133.1 45658047 2769843 complement(2651131..2652231) 1 NC_005823.1 degT family; identified by sequence similarity; ORF located using Blastx/Glimmer; aminotransferase 2652231 2769843 LIC12198 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aminotransferase YP_002133.1 2651131 R 267671 CDS YP_002134.1 45658048 2769704 complement(2652237..2653229) 1 NC_005823.1 UDP-glucose 4-epimerase 2653229 2769704 LIC12199 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-glucose 4-epimerase YP_002134.1 2652237 R 267671 CDS YP_002135.1 45658049 2772388 complement(2653232..2654761) 1 NC_005823.1 ADP-heptose synthetase 2654761 2772388 LIC12200 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ADP-heptose synthetase YP_002135.1 2653232 R 267671 CDS YP_002136.1 45658050 2770489 complement(2654758..2655561) 1 NC_005823.1 mannose-1-phosphate guanyltransferase 2655561 2770489 LIC12201 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 mannose-1-phosphate guanyltransferase YP_002136.1 2654758 R 267671 CDS YP_002137.1 45658051 2771680 complement(2655542..2656531) 1 NC_005823.1 UDP-glucose 4-epimerase 2656531 2771680 LIC12202 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-glucose 4-epimerase YP_002137.1 2655542 R 267671 CDS YP_002138.1 45658052 2769891 complement(2656538..2657095) 1 NC_005823.1 phosphoheptose isomerase 2657095 2769891 LIC12203 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoheptose isomerase YP_002138.1 2656538 R 267671 CDS YP_002139.1 45658053 2770597 complement(2657127..2658224) 1 NC_005823.1 FAD-dependent oxidoreductase family protein 2658224 2770597 LIC12204 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 FAD-dependent oxidoreductase family protein YP_002139.1 2657127 R 267671 CDS YP_002140.1 45658054 2769983 complement(2658241..2659185) 1 NC_005823.1 GDP-l-fucose synthetase 2659185 fcl 2769983 fcl Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GDP-l-fucose synthetase YP_002140.1 2658241 R 267671 CDS YP_002141.1 45658055 2770860 complement(2659190..2659510) 1 NC_005823.1 MarR family transcriptional regulator 2659510 2770860 LIC12206 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 MarR family transcriptional regulator YP_002141.1 2659190 R 267671 CDS YP_002142.1 45658056 2770687 2662267..2662839 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 2662839 2770687 LIC12207 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002142.1 2662267 D 267671 CDS YP_002143.1 45658057 2770475 2663730..2665154 1 NC_005823.1 lipoprotein 2665154 2770475 LIC12208 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002143.1 2663730 D 267671 CDS YP_002144.1 45658058 2772167 2665593..2667008 1 NC_005823.1 lipoprotein 2667008 2772167 LIC12209 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002144.1 2665593 D 267671 CDS YP_002145.1 45658059 2770113 2668228..2668644 1 NC_005823.1 small heat-shock protein; Hsp15-like protein 2668644 2770113 LIC12210 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Hsp15-like protein YP_002145.1 2668228 D 267671 CDS YP_002146.1 45658060 2771225 2668665..2669057 1 NC_005823.1 small heat-shock protein; Hsp15 2669057 hsp15 2771225 hsp15 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Hsp15 YP_002146.1 2668665 D 267671 CDS YP_002147.1 45658061 2770970 2670397..2670744 1 NC_005823.1 hypothetical protein 2670744 2770970 LIC12212 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002147.1 2670397 D 267671 CDS YP_002148.1 45658062 2772369 complement(2670779..2671555) 1 NC_005823.1 hypothetical protein 2671555 2772369 LIC12213 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002148.1 2670779 R 267671 CDS YP_002149.1 45658063 2770886 complement(2671711..2672304) 1 NC_005823.1 cytochrome oxidase assembly factor 2672304 2770886 LIC12214 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytochrome oxidase assembly factor YP_002149.1 2671711 R 267671 CDS YP_002150.1 45658064 2770668 complement(2672650..2673681) 1 NC_005823.1 hypothetical protein 2673681 2770668 LIC12215 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002150.1 2672650 R 267671 CDS YP_002151.1 45658065 2770340 complement(2673668..2674048) 1 NC_005823.1 hypothetical protein 2674048 2770340 LIC12216 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002151.1 2673668 R 267671 CDS YP_002152.1 45658066 2770883 complement(2674023..2676044) 1 NC_005823.1 lipoprotein 2676044 2770883 LIC12217 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002152.1 2674023 R 267671 CDS YP_002153.1 45658067 2771933 2676330..2677589 1 NC_005823.1 histidine kinase sensor protein 2677589 2771933 LIC12218 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_002153.1 2676330 D 267671 CDS YP_002154.1 45658068 2772735 2677754..2678287 1 NC_005823.1 hypothetical protein 2678287 2772735 LIC12219 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002154.1 2677754 D 267671 CDS YP_002155.1 45658069 2770587 2678288..2679139 1 NC_005823.1 beta-lactamase regulatory protein 1 2679139 blaR1 2770587 blaR1 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 beta-lactamase regulatory protein 1 YP_002155.1 2678288 D 267671 CDS YP_002156.1 45658070 2770856 2679159..2681411 1 NC_005823.1 cation:proton antiporter 2681411 2770856 LIC12221 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cation:proton antiporter YP_002156.1 2679159 D 267671 CDS YP_002157.1 45658071 2770736 2681540..2682634 1 NC_005823.1 DNA methyltransferase 2682634 2770736 LIC12222 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA methyltransferase YP_002157.1 2681540 D 267671 CDS YP_002158.1 45658072 2770420 complement(2683272..2683796) 1 NC_005823.1 hypothetical protein 2683796 2770420 LIC12223 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002158.1 2683272 R 267671 CDS YP_002159.1 45658073 2771359 2684117..2687413 1 NC_005823.1 heavy metal efflux pump 2687413 2771359 LIC12224 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heavy metal efflux pump YP_002159.1 2684117 D 267671 CDS YP_002160.1 45658074 2770057 2687885..2689903 1 NC_005823.1 hypothetical protein 2689903 2770057 LIC12225 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002160.1 2687885 D 267671 CDS YP_002161.1 45658075 2772330 2689926..2690768 1 NC_005823.1 hypothetical protein 2690768 2772330 LIC12226 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002161.1 2689926 D 267671 CDS YP_002162.1 45658076 2770933 2691534..2692034 1 NC_005823.1 hypothetical protein 2692034 2770933 LIC12227 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002162.1 2691534 D 267671 CDS YP_002163.1 45658077 2771982 2692055..2692537 1 NC_005823.1 hypothetical protein 2692537 2771982 LIC12228 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002163.1 2692055 D 267671 CDS YP_002164.1 45658078 2771575 complement(2692676..2693158) 1 NC_005823.1 hypothetical protein 2693158 2771575 LIC12229 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002164.1 2692676 R 267671 CDS YP_002165.1 45658079 2771050 complement(2693159..2693806) 1 NC_005823.1 hypothetical protein 2693806 2771050 LIC12230 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002165.1 2693159 R 267671 CDS YP_002166.1 45658080 2770526 complement(2693920..2694477) 1 NC_005823.1 hypothetical protein 2694477 2770526 LIC12231 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002166.1 2693920 R 267671 CDS YP_002167.2 304570497 2771749 2695022..2696596 1 NC_005823.1 thymidylate synthase 2696596 thyX 2771749 thyX Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thymidylate synthase YP_002167.2 2695022 D 267671 CDS YP_002168.1 45658082 2770673 complement(2697495..2698550) 1 NC_005823.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 2698550 2770673 LIC12233 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 fructose-bisphosphate aldolase YP_002168.1 2697495 R 267671 CDS YP_002169.1 45658083 2770135 2699585..2700088 1 NC_005823.1 internal repeat sequences detected; contains Leucine Rich Repeat as detected by pfam-hmmr; hypothetical protein 2700088 2770135 LIC12234 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002169.1 2699585 D 267671 CDS YP_002170.1 45658084 2770608 complement(2700653..2702119) 1 NC_005823.1 histidine kinase response regulator hybrid protein 2702119 2770608 LIC12235 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase response regulator hybrid protein YP_002170.1 2700653 R 267671 CDS YP_002171.1 45658085 2770804 2702491..2702931 1 NC_005823.1 hypothetical protein 2702931 2770804 LIC12236 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002171.1 2702491 D 267671 CDS YP_002172.1 45658086 2772242 2703112..2703306 1 NC_005823.1 hypothetical protein 2703306 2772242 LIC12237 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002172.1 2703112 D 267671 CDS YP_002173.1 45658087 2771879 2703303..2703818 1 NC_005823.1 hypothetical protein 2703818 2771879 LIC12238 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002173.1 2703303 D 267671 CDS YP_002174.1 45658088 2770774 complement(2703834..2704103) 1 NC_005823.1 hypothetical protein 2704103 2770774 LIC12239 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002174.1 2703834 R 267671 CDS YP_002175.1 45658089 2771082 complement(2705786..2706250) 1 NC_005823.1 chemotaxis protein 2706250 2771082 LIC12240 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chemotaxis protein YP_002175.1 2705786 R 267671 CDS YP_002176.1 45658090 2772805 complement(2706259..2706750) 1 NC_005823.1 hypothetical protein 2706750 2772805 LIC12241 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002176.1 2706259 R 267671 CDS YP_002177.1 45658091 2772102 2706939..2707178 1 NC_005823.1 hypothetical protein 2707178 2772102 LIC12242 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002177.1 2706939 D 267671 CDS YP_002178.1 45658092 2770976 complement(2707221..2708282) 1 NC_005823.1 mannose-1-phosphate guanylyltransferase 2708282 manC 2770976 manC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 mannose-1-phosphate guanylyltransferase YP_002178.1 2707221 R 267671 CDS YP_002179.1 45658093 2772409 complement(2708279..2709154) 1 NC_005823.1 hypothetical protein 2709154 2772409 LIC12244 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002179.1 2708279 R 267671 CDS YP_002180.1 45658094 2770659 complement(2709154..2709411) 1 NC_005823.1 host factor-1 2709411 hfq 2770659 hfq Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 host factor-1 YP_002180.1 2709154 R 267671 CDS YP_002181.1 45658095 2772866 complement(2709428..2710321) 1 NC_005823.1 tRNA delta(2)-isopentenylpyrophosphate transferase 2710321 miaA 2772866 miaA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002181.1 2709428 R 267671 CDS YP_002182.1 45658096 2772914 complement(2710331..2710846) 1 NC_005823.1 hypothetical protein 2710846 2772914 LIC12247 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002182.1 2710331 R 267671 CDS YP_002183.1 45658097 2772936 2711173..2711925 1 NC_005823.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 2711925 pdxJ 2772936 pdxJ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pyridoxine 5'-phosphate synthase YP_002183.1 2711173 D 267671 CDS YP_002184.1 45658098 2770433 complement(2711897..2712916) 1 NC_005823.1 hypothetical protein 2712916 2770433 LIC12249 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002184.1 2711897 R 267671 CDS YP_002185.1 45658099 2772768 2712909..2714681 1 NC_005823.1 carboxy-terminal processing protease 2714681 2772768 LIC12250 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 carboxy-terminal processing protease YP_002185.1 2712909 D 267671 CDS YP_002186.1 45658100 2772052 2714683..2716281 1 NC_005823.1 quinolinate synthetase b; L-aspartate oxidase 2716281 nadB 2772052 nadB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 L-aspartate oxidase YP_002186.1 2714683 D 267671 CDS YP_002187.1 45658101 2770819 complement(2716820..2718424) 1 NC_005823.1 hypothetical protein 2718424 2770819 LIC12252 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002187.1 2716820 R 267671 CDS YP_002188.1 45658102 2770452 complement(2718956..2719639) 1 NC_005823.1 lipoprotein 2719639 2770452 LIC12253 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002188.1 2718956 R 267671 CDS YP_002189.1 45658103 2772271 complement(2719647..2721215) 1 NC_005823.1 transmembrane protein; identified by sequence similarity; ORF located using Blastx/Glimmer; outer membrane protein 2721215 2772271 LIC12254 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 outer membrane protein YP_002189.1 2719647 R 267671 CDS YP_002190.1 45658104 2770578 2721246..2721521 1 NC_005823.1 hypothetical protein 2721521 2770578 LIC12255 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002190.1 2721246 D 267671 CDS YP_002191.1 45658105 2772852 complement(2722188..2722847) 1 NC_005823.1 membrane metalloendopeptidase 2722847 2772852 LIC12256 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 membrane metalloendopeptidase YP_002191.1 2722188 R 267671 CDS YP_002192.1 45658106 2771771 2723491..2724003 1 NC_005823.1 hypothetical protein 2724003 2771771 LIC12257 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002192.1 2723491 D 267671 CDS YP_002193.1 45658107 2770435 complement(2724988..2726439) 1 NC_005823.1 hypothetical protein 2726439 2770435 LIC12258 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002193.1 2724988 R 267671 CDS YP_002194.1 45658108 2770594 2727318..2730992 1 NC_005823.1 contains alpha integrin like repeat domains; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 2730992 2770594 LIC12259 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002194.1 2727318 D 267671 CDS YP_002195.1 45658109 2771572 2731061..2731903 1 NC_005823.1 hypothetical protein 2731903 2771572 LIC12260 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002195.1 2731061 D 267671 CDS YP_002196.1 45658110 2772062 2731927..2732334 1 NC_005823.1 hypothetical protein 2732334 2772062 LIC12261 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002196.1 2731927 D 267671 CDS YP_002197.1 45658111 2770499 complement(2733195..2733803) 1 NC_005823.1 hypothetical protein 2733803 2770499 LIC12262 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002197.1 2733195 R 267671 CDS YP_002198.1 45658112 2770109 complement(2733833..2734828) 1 NC_005823.1 hypothetical protein 2734828 2770109 LIC12263 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002198.1 2733833 R 267671 CDS YP_002199.1 45658113 2771570 complement(2735071..2735304) 1 NC_005823.1 hypothetical protein 2735304 2771570 LIC12264 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002199.1 2735071 R 267671 CDS YP_002200.1 45658114 2772529 complement(2735463..2735984) 1 NC_005823.1 hypothetical protein 2735984 2772529 LIC12265 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002200.1 2735463 R 267671 CDS YP_002201.1 45658115 2771645 complement(2736180..2737586) 1 NC_005823.1 Na+/H+ antiporter 2737586 2771645 LIC12266 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Na+/H+ antiporter YP_002201.1 2736180 R 267671 CDS YP_002202.1 45658116 2770661 complement(2737583..2738767) 1 NC_005823.1 ribosomal large subunit pseudouridine synthase C 2738767 rluC 2770661 rluC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribosomal large subunit pseudouridine synthase C YP_002202.1 2737583 R 267671 CDS YP_003858666.1 304570509 9714941 complement(2738689..2739762) 1 NC_005823.1 hypothetical protein 2739762 9714941 LIC14002 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003858666.1 2738689 R 267671 CDS YP_002203.1 45658117 2770547 complement(2739843..2742125) 1 NC_005823.1 glycolate oxidase 2742125 2770547 LIC12268 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycolate oxidase YP_002203.1 2739843 R 267671 CDS YP_002204.1 45658118 2770171 complement(2742142..2743242) 1 NC_005823.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 2743242 mnmA 2770171 mnmA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tRNA-specific 2-thiouridylase MnmA YP_002204.1 2742142 R 267671 CDS YP_002205.1 45658119 2770775 complement(2743266..2744213) 1 NC_005823.1 hypothetical protein 2744213 2770775 LIC12270 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002205.1 2743266 R 267671 CDS YP_002206.1 45658120 2770584 complement(2744192..2744422) 1 NC_005823.1 hypothetical protein 2744422 2770584 LIC12271 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002206.1 2744192 R 267671 CDS YP_002207.1 45658121 2770802 2744396..2744602 1 NC_005823.1 hypothetical protein 2744602 2770802 LIC12272 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002207.1 2744396 D 267671 CDS YP_002208.2 304570498 2770643 complement(2745881..2746939) 1 NC_005823.1 GGDEF family protein 2746939 2770643 LIC12273 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GGDEF family protein YP_002208.2 2745881 R 267671 CDS YP_002209.1 45658123 2770494 complement(2747745..2748518) 1 NC_005823.1 pyrroline-5-carboxylate reductase 2748518 proC 2770494 proC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pyrroline-5-carboxylate reductase YP_002209.1 2747745 R 267671 CDS YP_002210.1 45658124 2770014 complement(2748520..2749188) 1 NC_005823.1 hypothetical protein 2749188 2770014 LIC12276 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002210.1 2748520 R 267671 CDS YP_002211.1 45658125 2772035 complement(2749190..2749918) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 2749918 2772035 LIC12277 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002211.1 2749190 R 267671 CDS YP_002212.1 45658126 2770703 2749988..2750746 1 NC_005823.1 hypothetical protein 2750746 2770703 LIC12278 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002212.1 2749988 D 267671 CDS YP_002213.1 45658127 2772516 complement(2750718..2751359) 1 NC_005823.1 haloacid dehalogenase-like hydrolase 2751359 2772516 LIC12279 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 haloacid dehalogenase-like hydrolase YP_002213.1 2750718 R 267671 CDS YP_002214.1 45658128 2770693 2751342..2752598 1 NC_005823.1 3-deoxy-d-manno-octulosonic acid transferase 2752598 kdtA 2770693 kdtA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-deoxy-d-manno-octulosonic acid transferase YP_002214.1 2751342 D 267671 CDS YP_002215.1 45658129 2770615 complement(2752934..2753290) 1 NC_005823.1 hypothetical protein 2753290 2770615 LIC12281 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002215.1 2752934 R 267671 CDS YP_002216.1 45658130 2771346 complement(2753721..2754803) 1 NC_005823.1 hypothetical protein 2754803 2771346 LIC12282 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002216.1 2753721 R 267671 CDS YP_002217.1 45658131 2770173 2754933..2755475 1 NC_005823.1 hypothetical protein 2755475 2770173 LIC12283 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002217.1 2754933 D 267671 CDS YP_002218.1 45658132 2770863 2755560..2755832 1 NC_005823.1 hypothetical protein 2755832 2770863 LIC12284 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002218.1 2755560 D 267671 CDS YP_002219.1 45658133 2770052 complement(2755852..2757966) 1 NC_005823.1 H+-PPase; pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 2757966 hppA 2770052 hppA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 membrane-bound proton-translocating pyrophosphatase YP_002219.1 2755852 R 267671 CDS YP_002220.1 45658134 2772508 2758013..2759197 1 NC_005823.1 hypothetical protein 2759197 2772508 LIC12286 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002220.1 2758013 D 267671 CDS YP_002221.1 45658135 2770550 2759898..2760341 1 NC_005823.1 lipoprotein 2760341 2770550 LIC12287 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002221.1 2759898 D 267671 CDS YP_002222.1 45658136 2771128 2760363..2760686 1 NC_005823.1 lipoprotein 2760686 2771128 LIC12288 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002222.1 2760363 D 267671 CDS YP_002223.1 45658137 2770421 2760662..2761030 1 NC_005823.1 lipoprotein 2761030 2770421 LIC12289 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002223.1 2760662 D 267671 CDS YP_002224.1 45658138 2771685 complement(2761992..2763626) 1 NC_005823.1 oligo-1,6- glucosidase 2763626 malL 2771685 malL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 oligo-1,6- glucosidase YP_002224.1 2761992 R 267671 CDS YP_002225.1 45658139 2770396 2763905..2765305 1 NC_005823.1 UDP-N-acetylmuramyl pentapeptide synthase 2765305 murF 2770396 murF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-N-acetylmuramyl pentapeptide synthase YP_002225.1 2763905 D 267671 CDS YP_002226.1 45658140 2770837 2765356..2765844 1 NC_005823.1 phosphoribosylaminoimidazole carboxylase catalytic subunit protein 2765844 purE 2770837 purE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoribosylaminoimidazole carboxylase catalytic subunit protein YP_002226.1 2765356 D 267671 CDS YP_002227.1 45658141 2769922 2765841..2766971 1 NC_005823.1 phosphoribosylaminoimidazole carboxylase ATPase subunit protein 2766971 purK 2769922 purK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoribosylaminoimidazole carboxylase ATPase subunit protein YP_002227.1 2765841 D 267671 CDS YP_002228.1 45658142 2772017 complement(2768357..2769667) 1 NC_005823.1 UDP-glucose dehydrogenase 2769667 ugd 2772017 ugd Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-glucose dehydrogenase YP_002228.1 2768357 R 267671 CDS YP_002229.1 45658143 2770326 complement(2769716..2771014) 1 NC_005823.1 ABC transporter ATP-binding protein 2771014 2770326 LIC12295 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_002229.1 2769716 R 267671 CDS YP_002230.1 45658144 2771087 complement(2771011..2771679) 1 NC_005823.1 ABC transporter permease 2771679 2771087 LIC12296 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter permease YP_002230.1 2771011 R 267671 CDS YP_002231.1 45658145 2770161 complement(2771760..2772458) 1 NC_005823.1 DNA repair protein 2772458 2770161 LIC12297 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA repair protein YP_002231.1 2771760 R 267671 CDS YP_002232.1 45658146 2769999 complement(2772455..2772715) 1 NC_005823.1 hypothetical protein 2772715 2769999 LIC12298 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002232.1 2772455 R 267671 CDS YP_002233.1 45658147 2770891 2772974..2774050 1 NC_005823.1 hypothetical protein 2774050 2770891 LIC12299 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002233.1 2772974 D 267671 CDS YP_002234.1 45658148 2770801 2774047..2775927 1 NC_005823.1 hypothetical protein 2775927 2770801 LIC12300 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002234.1 2774047 D 267671 CDS YP_002235.1 45658149 2770634 complement(2776085..2776849) 1 NC_005823.1 phosphatidylserine synthase 2776849 pssA 2770634 pssA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphatidylserine synthase YP_002235.1 2776085 R 267671 CDS YP_002236.1 45658150 2772480 complement(2776846..2777862) 1 NC_005823.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 2777862 2772480 LIC12302 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA-binding/iron metalloprotein/AP endonuclease YP_002236.1 2776846 R 267671 CDS YP_002237.1 45658151 2769835 complement(2777867..2779255) 1 NC_005823.1 carboxy-terminal processing protease 2779255 2769835 LIC12303 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 carboxy-terminal processing protease YP_002237.1 2777867 R 267671 CDS YP_002238.1 45658152 2770900 complement(2779245..2779565) 1 NC_005823.1 hypothetical protein 2779565 2770900 LIC12304 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002238.1 2779245 R 267671 CDS YP_002239.1 45658153 2770381 complement(2779574..2780194) 1 NC_005823.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 2780194 lexA 2770381 lexA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 LexA repressor YP_002239.1 2779574 R 267671 CDS YP_002240.1 45658154 2770524 complement(2780238..2781419) 1 NC_005823.1 heavy metal efflux pump 2781419 czcB 2770524 czcB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heavy metal efflux pump YP_002240.1 2780238 R 267671 CDS YP_002241.1 45658155 2769749 complement(2781437..2782897) 1 NC_005823.1 TolC superfamily outer membrane protein 2782897 2769749 LIC12307 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 TolC superfamily outer membrane protein YP_002241.1 2781437 R 267671 CDS YP_002242.1 45658156 2772591 complement(2782873..2783481) 1 NC_005823.1 hypothetical protein 2783481 2772591 LIC12308 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002242.1 2782873 R 267671 CDS YP_002243.1 45658157 2769722 complement(2784690..2786249) 1 NC_005823.1 internal repeat sequences detected; contains TPR domain as detected by pfam-hmmr; hypothetical protein 2786249 2769722 LIC12309 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002243.1 2784690 R 267671 CDS YP_002244.1 45658158 2769546 2786364..2786888 1 NC_005823.1 hypothetical protein 2786888 2769546 LIC12310 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002244.1 2786364 D 267671 CDS YP_002245.1 45658159 2770742 2786885..2787550 1 NC_005823.1 ABC transporter ATP-binding protein 2787550 2770742 LIC12311 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_002245.1 2786885 D 267671 CDS YP_002246.1 45658160 2769478 2787547..2788443 1 NC_005823.1 glucokinase 2788443 glcK 2769478 glcK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glucokinase YP_002246.1 2787547 D 267671 CDS YP_002247.1 45658161 2772169 2788440..2788790 1 NC_005823.1 HIT family hydrolase 2788790 2772169 LIC12313 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 HIT family hydrolase YP_002247.1 2788440 D 267671 CDS YP_002248.1 45658162 2770065 2788801..2789817 1 NC_005823.1 hypothetical protein 2789817 2770065 LIC12314 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002248.1 2788801 D 267671 CDS YP_002249.1 45658163 2771543 2791576..2792889 1 NC_005823.1 lipoprotein 2792889 2771543 LIC12315 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002249.1 2791576 D 267671 CDS YP_002250.1 45658164 2770428 2793177..2793599 1 NC_005823.1 response regulator 2793599 2770428 LIC12316 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_002250.1 2793177 D 267671 CDS YP_002251.1 45658165 2770798 2794944..2796239 1 NC_005823.1 beta-ketoacyl synthase 2796239 sch1 2770798 sch1 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 beta-ketoacyl synthase YP_002251.1 2794944 D 267671 CDS YP_002252.1 45658166 2770887 2796250..2796777 1 NC_005823.1 hypothetical protein 2796777 2770887 LIC12318 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002252.1 2796250 D 267671 CDS YP_002253.1 45658167 2770619 complement(2796752..2797561) 1 NC_005823.1 protein phosphatase 2797561 2770619 LIC12319 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 protein phosphatase YP_002253.1 2796752 R 267671 CDS YP_002254.1 45658168 2770112 complement(2798006..2798776) 1 NC_005823.1 3-oxoacyl-[acyl-carrier protein] reductase 2798776 2770112 LIC12320 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-oxoacyl-[acyl-carrier protein] reductase YP_002254.1 2798006 R 267671 CDS YP_002255.1 45658169 2771624 complement(2799131..2799994) 1 NC_005823.1 hypothetical protein 2799994 2771624 LIC12321 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002255.1 2799131 R 267671 CDS YP_002256.1 45658170 2770877 2800414..2802195 1 NC_005823.1 glutaconate CoA transferase-like protein 2802195 2770877 LIC12322 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutaconate CoA transferase-like protein YP_002256.1 2800414 D 267671 CDS YP_002257.2 304570499 2770208 2802229..2803197 1 NC_005823.1 type III beta-ketoacyl synthase-like protein 2803197 2770208 LIC12323 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 type III beta-ketoacyl synthase-like protein YP_002257.2 2802229 D 267671 CDS YP_002258.1 45658172 2770482 2803222..2808564 1 NC_005823.1 serine/threonine kinase protein 2808564 2770482 LIC12324 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 serine/threonine kinase protein YP_002258.1 2803222 D 267671 CDS YP_002259.1 45658173 2770567 2808602..2809156 1 NC_005823.1 hypothetical protein 2809156 2770567 LIC12325 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002259.1 2808602 D 267671 CDS YP_002260.1 45658174 2770103 2809159..2809530 1 NC_005823.1 hypothetical protein 2809530 2770103 LIC12326 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002260.1 2809159 D 267671 CDS YP_002261.1 45658175 2770179 2809541..2811019 1 NC_005823.1 adenylate/guanylate cyclase 2811019 2770179 LIC12327 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_002261.1 2809541 D 267671 CDS YP_002262.1 45658176 2772790 complement(2811889..2812347) 1 NC_005823.1 lactoylglutathione lyase 2812347 2772790 LIC12328 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lactoylglutathione lyase YP_002262.1 2811889 R 267671 CDS YP_002263.1 45658177 2770782 complement(2813956..2814801) 1 NC_005823.1 hypothetical protein 2814801 2770782 LIC12331 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002263.1 2813956 R 267671 CDS YP_002264.1 45658178 2769832 complement(2815497..2816579) 1 NC_005823.1 hypothetical protein 2816579 2769832 LIC12332 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002264.1 2815497 R 267671 CDS YP_002265.1 45658179 2770912 2816692..2817714 1 NC_005823.1 hypothetical protein 2817714 2770912 LIC12333 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002265.1 2816692 D 267671 CDS YP_002266.1 45658180 2771560 2818377..2819363 1 NC_005823.1 lipoate-protein ligase a 2819363 lplA 2771560 lplA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoate-protein ligase a YP_002266.1 2818377 D 267671 CDS YP_002267.1 45658181 2771097 2819403..2820650 1 NC_005823.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 2820650 glyA 2771097 glyA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 serine hydroxymethyltransferase YP_002267.1 2819403 D 267671 CDS YP_002268.1 45658182 2769687 2821205..2822533 1 NC_005823.1 sterol desaturase-related protein 2822533 2769687 LIC12336 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sterol desaturase-related protein YP_002268.1 2821205 D 267671 CDS YP_002269.1 45658183 2769709 complement(2823637..2824824) 1 NC_005823.1 hypothetical protein 2824824 2769709 LIC12337 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002269.1 2823637 R 267671 CDS YP_002270.1 45658184 2769591 complement(2824821..2825141) 1 NC_005823.1 hypothetical protein 2825141 2769591 LIC12338 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002270.1 2824821 R 267671 CDS YP_002271.1 45658185 2770197 complement(2827132..2829123) 1 NC_005823.1 hypothetical protein 2829123 2770197 LIC12339 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002271.1 2827132 R 267671 CDS YP_002272.1 45658186 2769761 complement(2830042..2831925) 1 NC_005823.1 hypothetical protein 2831925 2769761 LIC12340 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002272.1 2830042 R 267671 CDS YP_002273.1 45658187 2769549 2834005..2834661 1 NC_005823.1 hypothetical protein 2834661 2769549 LIC12341 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002273.1 2834005 D 267671 CDS YP_002274.1 45658188 2769530 2834668..2837622 1 NC_005823.1 RND superfamily; identified by sequence similarity; ORF located using Blastx/Glimmer; export protein 2837622 2769530 LIC12342 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 export protein YP_002274.1 2834668 D 267671 CDS YP_002275.1 45658189 2769594 2837681..2838214 1 NC_005823.1 hypothetical protein 2838214 2769594 LIC12343 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002275.1 2837681 D 267671 CDS YP_002276.1 45658190 2769590 2838619..2838834 1 NC_005823.1 hypothetical protein 2838834 2769590 LIC12344 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002276.1 2838619 D 267671 CDS YP_002277.1 45658191 2769676 2838831..2839202 1 NC_005823.1 hypothetical protein 2839202 2769676 LIC12345 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002277.1 2838831 D 267671 CDS YP_002278.1 45658192 2769532 complement(2840289..2841275) 1 NC_005823.1 ribokinase 2841275 2769532 LIC12346 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribokinase YP_002278.1 2840289 R 267671 CDS YP_002279.1 45658193 2769652 complement(2841280..2842182) 1 NC_005823.1 ribosomal protein l11 methyltransferase 2842182 2769652 LIC12347 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribosomal protein l11 methyltransferase YP_002279.1 2841280 R 267671 CDS YP_002280.1 45658194 2769625 complement(2842179..2842931) 1 NC_005823.1 hypothetical protein 2842931 2769625 LIC12348 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002280.1 2842179 R 267671 CDS YP_002281.1 45658195 2769675 complement(2842928..2844652) 1 NC_005823.1 hypothetical protein 2844652 2769675 LIC12349 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002281.1 2842928 R 267671 CDS YP_002282.1 45658196 2769799 2844717..2846111 1 NC_005823.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 2846111 glyS 2769799 glyS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycyl-tRNA synthetase YP_002282.1 2844717 D 267671 CDS YP_002283.1 45658197 2769774 2846481..2846669 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 2846669 2769774 LIC12351 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002283.1 2846481 D 267671 CDS YP_002284.1 45658198 2769780 2847527..2847985 1 NC_005823.1 hypothetical protein 2847985 2769780 LIC12352 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002284.1 2847527 D 267671 CDS YP_002285.1 45658199 2769665 2848145..2849065 1 NC_005823.1 hypothetical protein 2849065 2769665 LIC12353 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002285.1 2848145 D 267671 CDS YP_002286.1 45658200 2769736 complement(2849874..2851055) 1 NC_005823.1 transcriptional regulator 2851055 2769736 LIC12354 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transcriptional regulator YP_002286.1 2849874 R 267671 CDS YP_002287.1 45658201 2769801 complement(2851409..2852620) 1 NC_005823.1 cell surface saccharide acetylase protein 2852620 yrhL 2769801 yrhL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cell surface saccharide acetylase protein YP_002287.1 2851409 R 267671 CDS YP_002288.1 45658202 2772919 complement(2853010..2853192) 1 NC_005823.1 hypothetical protein 2853192 2772919 LIC12356 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002288.1 2853010 R 267671 CDS YP_002289.1 45658203 2772900 complement(2853940..2855760) 1 NC_005823.1 GTP-binding protein; elongation factor EF-G 2855760 2772900 LIC12357 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 elongation factor EF-G YP_002289.1 2853940 R 267671 CDS YP_002290.1 45658204 2770364 2856367..2856942 1 NC_005823.1 hypothetical protein 2856942 2770364 LIC12358 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002290.1 2856367 D 267671 CDS YP_002291.1 45658205 2770670 2857824..2859146 1 NC_005823.1 hypothetical protein 2859146 2770670 LIC12359 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002291.1 2857824 D 267671 CDS YP_002292.1 45658206 2772401 complement(2859408..2860415) 1 NC_005823.1 pirin 2860415 pirin 2772401 pirin Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pirin YP_002292.1 2859408 R 267671 CDS YP_002293.1 45658207 2770104 complement(2861270..2862499) 1 NC_005823.1 major facilitator superfamily; MFS; identified by sequence similarity; ORF located using Blastx/Glimmer; permease 2862499 2770104 LIC12361 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 permease YP_002293.1 2861270 R 267671 CDS YP_002294.1 45658208 2770749 2862671..2863312 1 NC_005823.1 3-methyladenine DNA glycosylase 2863312 alkA 2770749 alkA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-methyladenine DNA glycosylase YP_002294.1 2862671 D 267671 CDS YP_002295.1 45658209 2769912 complement(2863315..2863866) 1 NC_005823.1 hypothetical protein 2863866 2769912 LIC12363 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002295.1 2863315 R 267671 CDS YP_002296.1 45658210 2771791 2864056..2866047 1 NC_005823.1 CagA 2866047 cagA 2771791 cagA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 CagA YP_002296.1 2864056 D 267671 CDS YP_002297.1 45658211 2770480 complement(2866628..2867797) 1 NC_005823.1 hypothetical protein 2867797 2770480 LIC12365 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002297.1 2866628 R 267671 CDS YP_002298.1 45658212 2771960 complement(2867811..2869343) 1 NC_005823.1 alginate O-acetyltransferase 2869343 2771960 LIC12366 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alginate O-acetyltransferase YP_002298.1 2867811 R 267671 CDS YP_002299.1 45658213 2770581 complement(2869379..2869750) 1 NC_005823.1 hypothetical protein 2869750 2770581 LIC12367 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002299.1 2869379 R 267671 CDS YP_002300.1 45658214 2772013 complement(2869757..2870953) 1 NC_005823.1 hypothetical protein 2870953 2772013 LIC12368 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002300.1 2869757 R 267671 CDS YP_002301.1 45658215 2770682 complement(2871127..2871642) 1 NC_005823.1 hypothetical protein 2871642 2770682 LIC12369 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002301.1 2871127 R 267671 CDS YP_002302.1 45658216 2770198 2871848..2872306 1 NC_005823.1 internal repeat sequences detected; contains internal repeats by prospero; hypothetical protein 2872306 2770198 LIC12370 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002302.1 2871848 D 267671 CDS YP_002303.1 45658217 2771940 complement(2873000..2873452) 1 NC_005823.1 hypothetical protein 2873452 2771940 LIC12371 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002303.1 2873000 R 267671 CDS YP_002304.1 45658218 2772127 complement(2873930..2874586) 1 NC_005823.1 ankyrin 2874586 2772127 LIC12372 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ankyrin YP_002304.1 2873930 R 267671 CDS YP_002305.1 45658219 2770114 complement(2875211..2876374) 1 NC_005823.1 hypothetical protein 2876374 2770114 LIC12373 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002305.1 2875211 R 267671 CDS YP_002306.1 45658220 2770039 complement(2876376..2878487) 1 NC_005823.1 outer membrane protein, TonB dependent 2878487 btuB 2770039 btuB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 outer membrane protein, TonB dependent YP_002306.1 2876376 R 267671 CDS YP_002307.1 45658221 2770416 complement(2879082..2879987) 1 NC_005823.1 contains leucine-rich repeats; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 2879987 2770416 LIC12375 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002307.1 2879082 R 267671 CDS YP_002308.1 45658222 2770783 complement(2880647..2880949) 1 NC_005823.1 hypothetical protein 2880949 2770783 LIC12376 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002308.1 2880647 R 267671 CDS YP_002309.1 45658223 2769876 complement(2881036..2882064) 1 NC_005823.1 capsule biosynthesis protein 2882064 capA 2769876 capA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 capsule biosynthesis protein YP_002309.1 2881036 R 267671 CDS YP_002310.1 45658224 2770688 2882151..2883014 1 NC_005823.1 3-demethylubiquinone-9 3-O-methyltransferase 2883014 ubiG 2770688 ubiG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-demethylubiquinone-9 3-O-methyltransferase YP_002310.1 2882151 D 267671 CDS YP_002311.1 45658225 2771852 2883898..2885286 1 NC_005823.1 histidine kinase sensor protein 2885286 2771852 LIC12379 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_002311.1 2883898 D 267671 CDS YP_002312.1 45658226 2769997 2885270..2885734 1 NC_005823.1 response regulator 2885734 2769997 LIC12380 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_002312.1 2885270 D 267671 CDS YP_002313.1 45658227 2770895 2886112..2887833 1 NC_005823.1 hypothetical protein 2887833 2770895 LIC12381 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002313.1 2886112 D 267671 CDS YP_002314.1 45658228 2770795 complement(2888165..2888881) 1 NC_005823.1 hypothetical protein 2888881 2770795 LIC12382 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002314.1 2888165 R 267671 CDS YP_002315.1 45658229 2770959 complement(2889207..2889416) 1 NC_005823.1 hypothetical protein 2889416 2770959 LIC12383 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002315.1 2889207 R 267671 CDS YP_002316.1 45658230 2772160 2889605..2890549 1 NC_005823.1 sodium bile acid symporter family protein 2890549 alr5254 2772160 alr5254 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sodium bile acid symporter family protein YP_002316.1 2889605 D 267671 CDS YP_002317.1 45658231 2770828 complement(2890689..2890886) 1 NC_005823.1 hypothetical protein 2890886 2770828 LIC12385 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002317.1 2890689 R 267671 CDS YP_002318.1 45658232 2772103 2890858..2891787 1 NC_005823.1 DME family; identified by sequence similarity; ORF located using Blastx/Glimmer; drug/metabolite exporter 2891787 2772103 LIC12386 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 drug/metabolite exporter YP_002318.1 2890858 D 267671 CDS YP_002319.1 45658233 2771655 complement(2892516..2893583) 1 NC_005823.1 permease 2893583 yljI 2771655 yljI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 permease YP_002319.1 2892516 R 267671 CDS YP_002320.1 45658234 2771557 complement(2893576..2894103) 1 NC_005823.1 cyclic nucleotide binding protein 2894103 2771557 LIC12388 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cyclic nucleotide binding protein YP_002320.1 2893576 R 267671 CDS YP_002321.1 45658235 2771970 complement(2894108..2894656) 1 NC_005823.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 2894656 lspA 2771970 lspA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein signal peptidase YP_002321.1 2894108 R 267671 CDS YP_002322.1 45658236 2770012 complement(2894653..2896365) 1 NC_005823.1 hypothetical protein 2896365 2770012 LIC12390 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002322.1 2894653 R 267671 CDS YP_002323.1 45658237 2770504 complement(2896377..2897546) 1 NC_005823.1 oxidoreductase 2897546 2770504 LIC12391 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 oxidoreductase YP_002323.1 2896377 R 267671 CDS YP_002324.1 45658238 2770845 complement(2898330..2899832) 1 NC_005823.1 6-aminohexanoate-cyclic-dimer hydrolase 2899832 nylA 2770845 nylA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 6-aminohexanoate-cyclic-dimer hydrolase YP_002324.1 2898330 R 267671 CDS YP_002325.1 45658239 2772760 2899947..2900930 1 NC_005823.1 ankyrin 2900930 2772760 LIC12393 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ankyrin YP_002325.1 2899947 D 267671 CDS YP_002326.1 45658240 2771822 complement(2901353..2901541) 1 NC_005823.1 hypothetical protein 2901541 2771822 LIC12394 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002326.1 2901353 R 267671 CDS YP_002327.1 45658241 2771498 complement(2901671..2902141) 1 NC_005823.1 hypothetical protein 2902141 2771498 LIC12395 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002327.1 2901671 R 267671 CDS YP_002328.1 45658242 2770377 complement(2902138..2902857) 1 NC_005823.1 hypothetical protein 2902857 2770377 LIC12396 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002328.1 2902138 R 267671 CDS YP_002329.1 45658243 2771287 complement(2902873..2904717) 1 NC_005823.1 hypothetical protein 2904717 2771287 LIC12397 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002329.1 2902873 R 267671 CDS YP_002330.1 45658244 2770295 2904788..2905192 1 NC_005823.1 anti-sigma factor antagonist 2905192 2770295 LIC12398 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_002330.1 2904788 D 267671 CDS YP_002331.1 45658245 2770915 2905189..2905929 1 NC_005823.1 hypothetical protein 2905929 2770915 LIC12399 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002331.1 2905189 D 267671 CDS YP_002332.1 45658246 2772382 complement(2906306..2909050) 1 NC_005823.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 2909050 ileS 2772382 ileS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 isoleucyl-tRNA synthetase YP_002332.1 2906306 R 267671 CDS YP_002333.1 45658247 2772608 complement(2909058..2909711) 1 NC_005823.1 contains leucine-rich repeats; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 2909711 2772608 LIC12401 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002333.1 2909058 R 267671 CDS YP_002334.1 45658248 2772215 complement(2909727..2911964) 1 NC_005823.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 2911964 purQ 2772215 purQ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoribosylformylglycinamidine synthase II YP_002334.1 2909727 R 267671 CDS YP_002335.1 45658249 2770614 complement(2911940..2912173) 1 NC_005823.1 hypothetical protein 2912173 2770614 LIC12403 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002335.1 2911940 R 267671 CDS YP_002336.1 45658250 2770691 complement(2913321..2914697) 1 NC_005823.1 disulfide interchange transmembrane protein 2914697 dsbD 2770691 dsbD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 disulfide interchange transmembrane protein YP_002336.1 2913321 R 267671 CDS YP_002337.1 45658251 2772520 2915803..2916516 1 NC_005823.1 hypothetical protein 2916516 2772520 LIC12405 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002337.1 2915803 D 267671 CDS YP_002338.1 45658252 2771857 complement(2916833..2917390) 1 NC_005823.1 hypothetical protein 2917390 2771857 LIC12406 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002338.1 2916833 R 267671 CDS YP_002339.1 45658253 2771731 complement(2918187..2919608) 1 NC_005823.1 glutamine synthetase protein 2919608 glnA 2771731 glnA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutamine synthetase protein YP_002339.1 2918187 R 267671 CDS YP_002340.1 45658254 2770227 2919712..2921229 1 NC_005823.1 hypothetical protein 2921229 2770227 LIC12408 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002340.1 2919712 D 267671 CDS YP_002341.1 45658255 2771896 2921380..2921670 1 NC_005823.1 hypothetical protein 2921670 2771896 LIC12410 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002341.1 2921380 D 267671 CDS YP_002342.1 45658256 2772351 2922235..2922765 1 NC_005823.1 hypothetical protein 2922765 2772351 LIC12411 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002342.1 2922235 D 267671 CDS YP_002343.1 45658257 2770649 complement(2922888..2925662) 1 NC_005823.1 chromosome segregation protein 2925662 2770649 LIC12412 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome segregation protein YP_002343.1 2922888 R 267671 CDS YP_002344.1 45658258 2770927 2925753..2927582 1 NC_005823.1 hypothetical protein 2927582 2770927 LIC12413 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002344.1 2925753 D 267671 CDS YP_002345.1 45658259 2771858 complement(2929139..2929351) 1 NC_005823.1 hypothetical protein 2929351 2771858 LIC12414 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002345.1 2929139 R 267671 CDS YP_002346.1 45658260 2770818 complement(2929440..2930240) 1 NC_005823.1 hypothetical protein 2930240 2770818 LIC12415 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002346.1 2929440 R 267671 CDS YP_002347.1 45658261 2770167 complement(2930215..2930865) 1 NC_005823.1 membrane protein 2930865 2770167 LIC12416 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 membrane protein YP_002347.1 2930215 R 267671 CDS YP_002348.1 45658262 2771800 complement(2930862..2932331) 1 NC_005823.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 2932331 engA 2771800 engA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GTP-binding protein EngA YP_002348.1 2930862 R 267671 CDS YP_002349.1 45658263 2771109 complement(2932356..2932838) 1 NC_005823.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 2932838 smpB 2771109 smpB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 SsrA-binding protein YP_002349.1 2932356 R 267671 CDS YP_002350.1 45658264 2770402 2933588..2935846 1 NC_005823.1 ankyrin 2935846 2770402 LIC12419 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ankyrin YP_002350.1 2933588 D 267671 CDS YP_002351.1 45658265 2770809 complement(2936234..2936812) 1 NC_005823.1 hypothetical protein 2936812 2770809 LIC12420 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002351.1 2936234 R 267671 CDS YP_002352.1 45658266 2769942 complement(2937356..2940388) 1 NC_005823.1 hypothetical protein 2940388 2769942 LIC12421 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002352.1 2937356 R 267671 CDS YP_002353.1 45658267 2769967 2941571..2942671 1 NC_005823.1 aspartate aminotransferase a 2942671 aspB 2769967 aspB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aspartate aminotransferase a YP_002353.1 2941571 D 267671 CDS YP_002354.1 45658268 2770546 2942655..2943506 1 NC_005823.1 prepilin leader peptidase 2943506 pilD 2770546 pilD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 prepilin leader peptidase YP_002354.1 2942655 D 267671 CDS YP_002355.1 45658269 2770842 2943864..2944343 1 NC_005823.1 hypothetical protein 2944343 2770842 LIC12424 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002355.1 2943864 D 267671 CDS YP_002356.1 45658270 2771721 2944331..2944999 1 NC_005823.1 hypothetical protein 2944999 2771721 LIC12425 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002356.1 2944331 D 267671 CDS YP_002357.1 45658271 2770969 complement(2945439..2945852) 1 NC_005823.1 hypothetical protein 2945852 2770969 LIC12426 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002357.1 2945439 R 267671 CDS YP_002358.1 45658272 2770158 complement(2946281..2947513) 1 NC_005823.1 hypothetical protein 2947513 2770158 LIC12427 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002358.1 2946281 R 267671 CDS YP_002359.1 45658273 2770007 complement(2947562..2948287) 1 NC_005823.1 ABC transporter ATP-binding protein 2948287 phnL 2770007 phnL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_002359.1 2947562 R 267671 CDS YP_002360.1 45658274 2772040 complement(2948277..2949515) 1 NC_005823.1 lipoprotein releasing system, permease component 2949515 2772040 LIC12429 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein releasing system, permease component YP_002360.1 2948277 R 267671 CDS YP_002361.1 45658275 2770627 complement(2949515..2950330) 1 NC_005823.1 hypothetical protein 2950330 2770627 LIC12430 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002361.1 2949515 R 267671 CDS YP_002362.1 45658276 2770713 complement(2950361..2951116) 1 NC_005823.1 TetR family transcriptional regulator 2951116 2770713 LIC12431 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 TetR family transcriptional regulator YP_002362.1 2950361 R 267671 CDS YP_002363.1 45658277 2770091 complement(2951350..2951559) 1 NC_005823.1 hypothetical protein 2951559 2770091 LIC12432 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002363.1 2951350 R 267671 CDS YP_002364.1 45658278 2770468 2951737..2953725 1 NC_005823.1 phosphoglycerol transferase 2953725 mdoB 2770468 mdoB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoglycerol transferase YP_002364.1 2951737 D 267671 CDS YP_002365.1 45658279 2772159 complement(2953836..2954042) 1 NC_005823.1 hypothetical protein 2954042 2772159 LIC12434 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002365.1 2953836 R 267671 CDS YP_002366.1 45658280 2770766 complement(2954260..2954478) 1 NC_005823.1 hypothetical protein 2954478 2770766 LIC12435 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002366.1 2954260 R 267671 CDS YP_002367.1 45658281 2769883 complement(2954854..2956767) 1 NC_005823.1 hypothetical protein 2956767 2769883 LIC12436 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002367.1 2954854 R 267671 CDS YP_002368.1 45658282 2771978 2957365..2957865 1 NC_005823.1 hypothetical protein 2957865 2771978 LIC12437 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002368.1 2957365 D 267671 CDS YP_002369.1 45658283 2772041 2958782..2959333 1 NC_005823.1 transcriptional regulator 2959333 2772041 LIC12438 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transcriptional regulator YP_002369.1 2958782 D 267671 CDS YP_002370.1 45658284 2770084 complement(2959469..2959735) 1 NC_005823.1 hypothetical protein 2959735 2770084 LIC12439 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002370.1 2959469 R 267671 CDS YP_002371.1 45658285 2770126 complement(2960433..2960711) 1 NC_005823.1 hypothetical protein 2960711 2770126 LIC12440 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002371.1 2960433 R 267671 CDS YP_002372.1 45658286 2770706 complement(2960716..2960907) 1 NC_005823.1 hypothetical protein 2960907 2770706 LIC12441 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002372.1 2960716 R 267671 CDS YP_002373.1 45658287 2772007 complement(2961580..2962587) 1 NC_005823.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase 2962587 plsX 2772007 plsX Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycerol-3-phosphate acyltransferase YP_002373.1 2961580 R 267671 CDS YP_002374.1 45658288 2770577 complement(2962593..2962793) 1 NC_005823.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 2962793 rpmF 2770577 rpmF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L32 YP_002374.1 2962593 R 267671 CDS YP_002375.1 45658289 2769741 complement(2963090..2963710) 1 NC_005823.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase catalytic subunit 2963710 hisG 2769741 hisG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP phosphoribosyltransferase catalytic subunit YP_002375.1 2963090 R 267671 CDS YP_002376.1 45658290 2769575 complement(2963707..2964450) 1 NC_005823.1 internal repeat sequences detected; contains TPR domain as detected by pfam-hmmr; hypothetical protein 2964450 2769575 LIC12446 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002376.1 2963707 R 267671 CDS YP_002377.1 45658291 2769896 complement(2964475..2966157) 1 NC_005823.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 2966157 rpsA 2769896 rpsA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S1 YP_002377.1 2964475 R 267671 CDS YP_002378.1 45658292 2769618 complement(2966892..2968214) 1 NC_005823.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 2968214 aroA 2769618 aroA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-phosphoshikimate 1-carboxyvinyltransferase YP_002378.1 2966892 R 267671 CDS YP_002379.1 45658293 2769500 complement(2968195..2969112) 1 NC_005823.1 prephenate (chorismate) dehydrogenase 2969112 tyrA 2769500 tyrA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 prephenate (chorismate) dehydrogenase YP_002379.1 2968195 R 267671 CDS YP_002380.1 45658294 2769491 complement(2969109..2970215) 1 NC_005823.1 chorismate mutase and prephenate dehydratase 2970215 pheA 2769491 pheA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chorismate mutase and prephenate dehydratase YP_002380.1 2969109 R 267671 CDS YP_002381.1 45658295 2769475 complement(2970193..2970756) 1 NC_005823.1 hypothetical protein 2970756 2769475 LIC12452 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002381.1 2970193 R 267671 CDS YP_002382.1 45658296 2771581 complement(2970723..2971508) 1 NC_005823.1 hypothetical protein 2971508 2771581 LIC12453 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002382.1 2970723 R 267671 CDS YP_002383.1 45658297 2771661 complement(2971526..2971888) 1 NC_005823.1 response regulator 2971888 2771661 LIC12454 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_002383.1 2971526 R 267671 CDS YP_002384.1 45658298 2772514 complement(2971890..2972963) 1 NC_005823.1 protein-glutamate methylesterase 2972963 2772514 LIC12455 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 protein-glutamate methylesterase YP_002384.1 2971890 R 267671 CDS YP_002385.1 45658299 2769645 complement(2976181..2976714) 1 NC_005823.1 chemotaxis protein 2976714 2769645 LIC12457 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chemotaxis protein YP_002385.1 2976181 R 267671 CDS YP_002386.1 45658300 2772191 complement(2977283..2977813) 1 NC_005823.1 5-formyltetrahydrofolate cyclo-ligase 2977813 2772191 LIC12458 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 5-formyltetrahydrofolate cyclo-ligase YP_002386.1 2977283 R 267671 CDS YP_002387.1 45658301 2770434 complement(2977843..2978184) 1 NC_005823.1 hypothetical protein 2978184 2770434 LIC12459 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002387.1 2977843 R 267671 CDS YP_002388.1 45658302 2770162 complement(2978168..2978806) 1 NC_005823.1 hypothetical protein 2978806 2770162 LIC12460 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002388.1 2978168 R 267671 CDS YP_002389.1 45658303 2771948 complement(2978894..2979247) 1 NC_005823.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2979247 rplT 2771948 rplT Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L20 YP_002389.1 2978894 R 267671 CDS YP_002390.1 45658304 2769698 complement(2979247..2979450) 1 NC_005823.1 50S ribosomal protein L35 2979450 rpmI 2769698 rpmI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L35 YP_002390.1 2979247 R 267671 CDS YP_002391.1 45658305 2770558 complement(2979483..2980022) 1 NC_005823.1 IF-3; IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 2980022 infC 2770558 infC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 translation initiation factor IF-3 YP_002391.1 2979483 R 267671 CDS YP_002392.1 45658306 2769725 2980926..2981564 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 2981564 2769725 LIC12464 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002392.1 2980926 D 267671 CDS YP_002393.1 45658307 2771424 complement(2981653..2983569) 1 NC_005823.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 2983569 thrS 2771424 thrS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 threonyl-tRNA synthetase YP_002393.1 2981653 R 267671 CDS YP_002394.1 45658308 2770074 2983819..2984910 1 NC_005823.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 2984910 carA 2770074 carA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 carbamoyl phosphate synthase small subunit YP_002394.1 2983819 D 267671 CDS YP_002395.1 45658309 2769748 2984916..2985104 1 NC_005823.1 hypothetical protein 2985104 2769748 LIC12467 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002395.1 2984916 D 267671 CDS YP_002396.1 45658310 2770709 2986975..2988528 1 NC_005823.1 hypothetical protein 2988528 2770709 LIC12468 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002396.1 2986975 D 267671 CDS YP_002397.1 45658311 2772396 2989495..2991306 1 NC_005823.1 chaperone protein; Hsp90 family; identified by sequence similarity; ORF located using Blastx/Glimmer; HSP90 family protein 2991306 2772396 LIC12469 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 HSP90 family protein YP_002397.1 2989495 D 267671 CDS YP_002398.1 45658312 2770192 2991303..2992421 1 NC_005823.1 hypothetical protein 2992421 2770192 LIC12470 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002398.1 2991303 D 267671 CDS YP_002399.1 45658313 2771419 complement(2993162..2993734) 1 NC_005823.1 hypothetical protein 2993734 2771419 LIC12471 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002399.1 2993162 R 267671 CDS YP_002400.1 45658314 2770327 complement(2994211..2994567) 1 NC_005823.1 acetyltransferase 2994567 2770327 LIC12472 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyltransferase YP_002400.1 2994211 R 267671 CDS YP_002401.1 45658315 2769868 complement(2994600..2994875) 1 NC_005823.1 hypothetical protein 2994875 2769868 LIC12473 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002401.1 2994600 R 267671 CDS YP_002402.1 45658316 2770761 complement(2995070..2997832) 1 NC_005823.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 2997832 sucA 2770761 sucA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 2-oxoglutarate dehydrogenase E1 component YP_002402.1 2995070 R 267671 CDS YP_002403.1 45658317 2772253 complement(2997856..2999259) 1 NC_005823.1 dihydrolipoamide dehydrogenase 2999259 lpdA 2772253 lpdA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dihydrolipoamide dehydrogenase YP_002403.1 2997856 R 267671 CDS YP_002404.1 45658318 2771011 complement(2999273..3000538) 1 NC_005823.1 dihydrolipoamide succinyltransferase 3000538 sucB 2771011 sucB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dihydrolipoamide succinyltransferase YP_002404.1 2999273 R 267671 CDS YP_002405.1 45658319 2770813 complement(3000626..3003064) 1 NC_005823.1 penicillin-binding protein; Pbp1A 3003064 pbp1a 2770813 pbp1a Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Pbp1A YP_002405.1 3000626 R 267671 CDS YP_002406.1 45658320 2770811 complement(3003061..3004017) 1 NC_005823.1 hypothetical protein 3004017 2770811 LIC12478 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002406.1 3003061 R 267671 CDS YP_002407.1 45658321 2770138 3004088..3004942 1 NC_005823.1 contains rhomboid domain; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 3004942 2770138 LIC12479 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002407.1 3004088 D 267671 CDS YP_002408.1 45658322 2771338 complement(3005142..3005546) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 3005546 2771338 LIC12480 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002408.1 3005142 R 267671 CDS YP_002409.1 45658323 2770826 3005783..3006388 1 NC_005823.1 amino-acid acetyltransferase 3006388 2770826 LIC12481 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 amino-acid acetyltransferase YP_002409.1 3005783 D 267671 CDS YP_002410.1 45658324 2772624 complement(3007589..3009391) 1 NC_005823.1 serine chemoreceptor; mcp-i; identified by sequence similarity; ORF located using Blastx/Glimmer; methyl-accepting chemotaxis I 3009391 2772624 LIC12482 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methyl-accepting chemotaxis I YP_002410.1 3007589 R 267671 CDS YP_002411.1 45658325 2770246 complement(3010671..3011501) 1 NC_005823.1 hypothetical protein 3011501 2770246 LIC12483 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002411.1 3010671 R 267671 CDS YP_002412.1 45658326 2770116 3011612..3012094 1 NC_005823.1 universal stress protein family; identified by sequence similarity; ORF located using Blastx/Glimmer; DNA binding protein 3012094 2770116 LIC12484 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA binding protein YP_002412.1 3011612 D 267671 CDS YP_002413.1 45658327 2769894 complement(3012095..3012658) 1 NC_005823.1 hypothetical protein 3012658 2769894 LIC12485 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002413.1 3012095 R 267671 CDS YP_002414.1 45658328 2771708 3012734..3013453 1 NC_005823.1 TerC family; identified by sequence similarity; ORF located using Blastx/Glimmer; integral membrane protein 3013453 2771708 LIC12486 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 integral membrane protein YP_002414.1 3012734 D 267671 CDS YP_002415.1 45658329 2770679 complement(3013440..3014834) 1 NC_005823.1 hypothetical protein 3014834 2770679 LIC12487 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002415.1 3013440 R 267671 CDS YP_002416.1 45658330 2770920 complement(3014958..3015380) 1 NC_005823.1 hypothetical protein 3015380 2770920 LIC12488 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002416.1 3014958 R 267671 CDS YP_002417.1 45658331 2770960 complement(3016071..3016634) 1 NC_005823.1 hypothetical protein 3016634 2770960 LIC12489 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002417.1 3016071 R 267671 CDS YP_002418.1 45658332 2771447 complement(3016639..3017259) 1 NC_005823.1 RNA polymerase ECF-type sigma factor 3017259 2771447 LIC12490 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA polymerase ECF-type sigma factor YP_002418.1 3016639 R 267671 CDS YP_002419.1 45658333 2770675 complement(3017323..3017682) 1 NC_005823.1 hypothetical protein 3017682 2770675 LIC12491 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002419.1 3017323 R 267671 CDS YP_002420.1 45658334 2770899 complement(3017815..3019218) 1 NC_005823.1 alginate O-acetyltransferase 3019218 algI 2770899 algI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alginate O-acetyltransferase YP_002420.1 3017815 R 267671 CDS YP_002421.1 45658335 2770095 3019386..3020051 1 NC_005823.1 lipoprotein 3020051 2770095 LIC12493 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002421.1 3019386 D 267671 CDS YP_002422.1 45658336 2771614 complement(3020152..3020640) 1 NC_005823.1 hypothetical protein 3020640 2771614 LIC12494 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002422.1 3020152 R 267671 CDS YP_002423.1 45658337 2771061 complement(3021213..3021986) 1 NC_005823.1 3-hydroxybutyryl-CoA dehydratase 3021986 crt 2771061 crt Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-hydroxybutyryl-CoA dehydratase YP_002423.1 3021213 R 267671 CDS YP_002424.1 45658338 2770945 complement(3021994..3023376) 1 NC_005823.1 sigma factor regulatory protein 3023376 2770945 LIC12496 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sigma factor regulatory protein YP_002424.1 3021994 R 267671 CDS YP_002425.1 45658339 2770626 complement(3023351..3023761) 1 NC_005823.1 hypothetical protein 3023761 2770626 LIC12497 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002425.1 3023351 R 267671 CDS YP_002426.1 45658340 2769870 3023844..3024869 1 NC_005823.1 hypothetical protein 3024869 2769870 LIC12498 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002426.1 3023844 D 267671 CDS YP_002427.1 45658341 2770465 3025736..3027307 1 NC_005823.1 hypothetical protein 3027307 2770465 LIC12499 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002427.1 3025736 D 267671 CDS YP_002428.1 45658342 2770925 3027333..3029408 1 NC_005823.1 chemoreceptor (methyl-accepting chemotaxis) transmembrane protein 3029408 mcpB 2770925 mcpB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chemoreceptor (methyl-accepting chemotaxis) transmembrane protein YP_002428.1 3027333 D 267671 CDS YP_002429.1 45658343 2770419 complement(3029437..3030378) 1 NC_005823.1 hypothetical protein 3030378 2770419 LIC12501 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002429.1 3029437 R 267671 CDS YP_002430.1 45658344 2771062 complement(3030430..3030717) 1 NC_005823.1 sigma-54 modulation protein 3030717 2771062 LIC12502 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sigma-54 modulation protein YP_002430.1 3030430 R 267671 CDS YP_002431.1 45658345 2770318 complement(3030882..3031331) 1 NC_005823.1 hypothetical protein 3031331 2770318 LIC12503 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002431.1 3030882 R 267671 CDS YP_002432.1 45658346 2772058 complement(3032482..3032871) 1 NC_005823.1 response regulator 3032871 2772058 LIC12504 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_002432.1 3032482 R 267671 CDS YP_002433.1 45658347 2772172 complement(3032992..3034701) 1 NC_005823.1 response regulator 3034701 2772172 LIC12505 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_002433.1 3032992 R 267671 CDS YP_002434.1 45658348 2770760 3034883..3036475 1 NC_005823.1 adenylate/guanylate cyclase 3036475 2770760 LIC12506 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_002434.1 3034883 D 267671 CDS YP_002435.1 45658349 2771775 complement(3036477..3036659) 1 NC_005823.1 hypothetical protein 3036659 2771775 LIC12507 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002435.1 3036477 R 267671 CDS YP_002436.1 45658350 2770752 3036789..3037901 1 NC_005823.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 3037901 hisC 2770752 hisC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidinol-phosphate aminotransferase YP_002436.1 3036789 D 267671 CDS YP_002437.1 45658351 2771886 3038710..3039027 1 NC_005823.1 hypothetical protein 3039027 2771886 LIC12509 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002437.1 3038710 D 267671 CDS YP_002438.1 45658352 2771265 complement(3039028..3040299) 1 NC_005823.1 associated with chromosome architecture/replication; identified by sequence similarity; ORF located using Blastx/Glimmer; recombination factor protein RarA 3040299 2771265 LIC12510 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 recombination factor protein RarA YP_002438.1 3039028 R 267671 CDS YP_002439.1 45658353 2771724 complement(3040296..3040523) 1 NC_005823.1 hypothetical protein 3040523 2771724 LIC12511 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002439.1 3040296 R 267671 CDS YP_002440.1 45658354 2772410 3040727..3041095 1 NC_005823.1 internal repeat sequences detected; contains Leucine rich repeat as detected by pfam-hmmr; hypothetical protein 3041095 2772410 LIC12512 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002440.1 3040727 D 267671 CDS YP_002441.1 45658355 2771041 complement(3041218..3041838) 1 NC_005823.1 hypothetical protein 3041838 2771041 LIC12513 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002441.1 3041218 R 267671 CDS YP_002442.1 45658356 2771374 complement(3041807..3043600) 1 NC_005823.1 DNA mismatch repair protein 3043600 mutL 2771374 mutL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA mismatch repair protein YP_002442.1 3041807 R 267671 CDS YP_002443.1 45658357 2769793 complement(3043801..3044793) 1 NC_005823.1 cystine-binding periplasmic protein precursor 3044793 2769793 LIC12515 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cystine-binding periplasmic protein precursor YP_002443.1 3043801 R 267671 CDS YP_002444.1 45658358 2770630 complement(3045302..3047284) 1 NC_005823.1 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; acetoacetyl-CoA synthetase 3047284 2770630 LIC12516 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetoacetyl-CoA synthetase YP_002444.1 3045302 R 267671 CDS YP_002445.1 45658359 2769982 3047417..3047821 1 NC_005823.1 hypothetical protein 3047821 2769982 LIC12517 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002445.1 3047417 D 267671 CDS YP_002446.1 45658360 2771526 complement(3048890..3049309) 1 NC_005823.1 hypothetical protein 3049309 2771526 LIC12518 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002446.1 3048890 R 267671 CDS YP_002447.1 45658361 2771909 complement(3049306..3049740) 1 NC_005823.1 hypothetical protein 3049740 2771909 LIC12519 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002447.1 3049306 R 267671 CDS YP_002448.1 45658362 2772265 complement(3049893..3050537) 1 NC_005823.1 pyridoxamine 5'-phosphate oxidase 3050537 pdxH 2772265 pdxH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pyridoxamine 5'-phosphate oxidase YP_002448.1 3049893 R 267671 CDS YP_002449.1 45658363 2772804 complement(3050958..3056237) 1 NC_005823.1 contains GAF domain; identified by sequence similarity; ORF located using Blastx/Glimmer; serine/threonine kinase 3056237 2772804 LIC12521 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 serine/threonine kinase YP_002449.1 3050958 R 267671 CDS YP_002450.1 45658364 2770554 complement(3056247..3056912) 1 NC_005823.1 hypothetical protein 3056912 2770554 LIC12522 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002450.1 3056247 R 267671 CDS YP_002451.1 45658365 2770681 complement(3056917..3058035) 1 NC_005823.1 hypothetical protein 3058035 2770681 LIC12523 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002451.1 3056917 R 267671 CDS YP_002452.1 45658366 2772482 3058082..3059539 1 NC_005823.1 fatty acid transport protein 3059539 salD 2772482 salD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 fatty acid transport protein YP_002452.1 3058082 D 267671 CDS YP_002453.1 45658367 2771941 3061176..3062384 1 NC_005823.1 lipoprotein 3062384 2771941 LIC12525 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002453.1 3061176 D 267671 CDS YP_002454.1 45658368 2771954 complement(3062915..3063985) 1 NC_005823.1 ABC transporter ATP-binding protein 3063985 cysA 2771954 cysA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_002454.1 3062915 R 267671 CDS YP_002455.1 45658369 2770951 complement(3063987..3064826) 1 NC_005823.1 sulfate ABC transporter permease 3064826 cysW 2770951 cysW Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sulfate ABC transporter permease YP_002455.1 3063987 R 267671 CDS YP_002456.1 45658370 2771475 complement(3064823..3065668) 1 NC_005823.1 sulfate ABC transporter permease 3065668 cysT 2771475 cysT Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sulfate ABC transporter permease YP_002456.1 3064823 R 267671 CDS YP_002457.1 45658371 2770533 complement(3065687..3066694) 1 NC_005823.1 sulfate ABC transporter substrate-binding protein 3066694 2770533 LIC12529 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sulfate ABC transporter substrate-binding protein YP_002457.1 3065687 R 267671 CDS YP_002458.1 45658372 2771397 3068122..3068466 1 NC_005823.1 hypothetical protein 3068466 2771397 LIC12530 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002458.1 3068122 D 267671 CDS YP_002459.1 45658373 2770191 complement(3068677..3069363) 1 NC_005823.1 hypothetical protein 3069363 2770191 LIC12531 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002459.1 3068677 R 267671 CDS YP_002460.1 45658374 2771221 complement(3069587..3069904) 1 NC_005823.1 hypothetical protein 3069904 2771221 LIC12532 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002460.1 3069587 R 267671 CDS YP_002461.1 45658375 2770369 complement(3070129..3070329) 1 NC_005823.1 hypothetical protein 3070329 2770369 LIC12533 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002461.1 3070129 R 267671 CDS YP_002462.1 45658376 2769893 complement(3070930..3072135) 1 NC_005823.1 bifunctional protein; identified by sequence similarity; ORF located using Blastx/Glimmer; RibA; GTP cyclohydrolase 2 3072135 ribA 2769893 ribA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GTP cyclohydrolase 2 YP_002462.1 3070930 R 267671 CDS YP_002463.1 45658377 2770697 complement(3073779..3074381) 1 NC_005823.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 3074381 risA 2770697 risA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 riboflavin synthase subunit alpha YP_002463.1 3073779 R 267671 CDS YP_002464.1 45658378 2772708 complement(3074366..3075766) 1 NC_005823.1 riboflavin biosynthesis protein (deaminase/reductase); hypothetical protein 3075766 ribD 2772708 ribD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002464.1 3074366 R 267671 CDS YP_002465.1 45658379 2772712 complement(3075766..3076734) 1 NC_005823.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 3076734 secF 2772712 secF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 preprotein translocase subunit SecF YP_002465.1 3075766 R 267671 CDS YP_002466.1 45658380 2771513 complement(3076709..3078637) 1 NC_005823.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 3078637 secD 2771513 secD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 preprotein translocase subunit SecD YP_002466.1 3076709 R 267671 CDS YP_002467.1 45658381 2770145 complement(3078648..3079394) 1 NC_005823.1 hypothetical protein 3079394 2770145 LIC12539 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002467.1 3078648 R 267671 CDS YP_002468.1 45658382 2770838 complement(3079391..3079717) 1 NC_005823.1 hypothetical protein 3079717 yajC 2770838 yajC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002468.1 3079391 R 267671 CDS YP_002469.1 45658383 2771367 complement(3079773..3080783) 1 NC_005823.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 3080783 trpD 2771367 trpD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anthranilate phosphoribosyltransferase YP_002469.1 3079773 R 267671 CDS YP_002470.1 45658384 2770861 complement(3080758..3081510) 1 NC_005823.1 phosphatidylglycerophosphate synthase 3081510 pgsA 2770861 pgsA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphatidylglycerophosphate synthase YP_002470.1 3080758 R 267671 CDS YP_002471.1 45658385 2772312 complement(3081501..3082814) 1 NC_005823.1 hypothetical protein 3082814 2772312 LIC12543 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002471.1 3081501 R 267671 CDS YP_002472.1 45658386 2770950 complement(3082823..3083938) 1 NC_005823.1 DNA binding protein 3083938 2770950 LIC12544 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA binding protein YP_002472.1 3082823 R 267671 CDS YP_002473.1 45658387 2770791 complement(3083960..3084733) 1 NC_005823.1 outer membrane lipoprotein carrier protein 3084733 lolA 2770791 lolA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 outer membrane lipoprotein carrier protein YP_002473.1 3083960 R 267671 CDS YP_002474.1 45658388 2770149 complement(3085192..3086367) 1 NC_005823.1 hypothetical protein 3086367 2770149 LIC12546 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002474.1 3085192 R 267671 CDS YP_002475.1 45658389 2771912 complement(3087570..3088001) 1 NC_005823.1 hypothetical protein 3088001 2771912 LIC12547 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002475.1 3087570 R 267671 CDS YP_002476.1 45658390 2770410 3088101..3088343 1 NC_005823.1 hypothetical protein 3088343 2770410 LIC12548 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002476.1 3088101 D 267671 CDS YP_002477.1 45658391 2770047 3088522..3089187 1 NC_005823.1 protein-L-isoaspartate O-methyltransferase 3089187 pcm 2770047 pcm Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 protein-L-isoaspartate O-methyltransferase YP_002477.1 3088522 D 267671 CDS YP_002478.1 45658392 2772524 3089357..3091057 1 NC_005823.1 acyl-CoA dehydrogenase 3091057 acd3 2772524 acd3 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyl-CoA dehydrogenase YP_002478.1 3089357 D 267671 CDS YP_002479.1 45658393 2772112 3091198..3091917 1 NC_005823.1 hypothetical protein 3091917 2772112 LIC12552 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002479.1 3091198 D 267671 CDS YP_002480.1 45658394 2770593 3091895..3092797 1 NC_005823.1 hypothetical protein 3092797 2770593 LIC12553 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002480.1 3091895 D 267671 CDS YP_002481.1 45658395 2770151 complement(3094124..3095143) 1 NC_005823.1 D-3-phosphoglycerate dehydrogenase 3095143 2770151 LIC12554 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 D-3-phosphoglycerate dehydrogenase YP_002481.1 3094124 R 267671 CDS YP_002482.1 45658396 2772452 3095230..3096264 1 NC_005823.1 hypothetical protein 3096264 2772452 LIC12555 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002482.1 3095230 D 267671 CDS YP_002483.1 45658397 2770009 3096271..3098001 1 NC_005823.1 apolipoprotein n-acyltransferase 3098001 lnt 2770009 lnt Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 apolipoprotein n-acyltransferase YP_002483.1 3096271 D 267671 CDS YP_002484.1 45658398 2770985 3098004..3098771 1 NC_005823.1 hypothetical protein 3098771 2770985 LIC12557 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002484.1 3098004 D 267671 CDS YP_002485.1 45658399 2770139 3099262..3099993 1 NC_005823.1 hypothetical protein 3099993 2770139 LIC12558 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002485.1 3099262 D 267671 CDS YP_002486.1 45658400 2772639 complement(3100454..3100975) 1 NC_005823.1 hypothetical protein 3100975 2772639 LIC12559 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002486.1 3100454 R 267671 CDS YP_002487.1 45658401 2771885 complement(3102519..3102956) 1 NC_005823.1 deoxyuridine 5'triphosphate nucleotidohydrolase 3102956 dut 2771885 dut Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 deoxyuridine 5'triphosphate nucleotidohydrolase YP_002487.1 3102519 R 267671 CDS YP_002488.1 45658402 2770406 3103359..3104309 1 NC_005823.1 hypothetical protein 3104309 2770406 LIC12561 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002488.1 3103359 D 267671 CDS YP_002489.1 45658403 2772532 complement(3105732..3106865) 1 NC_005823.1 ring hydroxylating dioxygenase alpha-subunit 3106865 2772532 LIC12562 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ring hydroxylating dioxygenase alpha-subunit YP_002489.1 3105732 R 267671 CDS YP_002490.1 45658404 2770824 complement(3107471..3109480) 1 NC_005823.1 glycerol-3-phosphate dehydrogenase 3109480 2770824 LIC12563 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycerol-3-phosphate dehydrogenase YP_002490.1 3107471 R 267671 CDS YP_002491.1 45658405 2772186 3109787..3110821 1 NC_005823.1 histidyl-tRNA synthetase class II core domain; ATP phosphoribosyltransferase regulatory subunit 3110821 hisZ 2772186 hisZ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP phosphoribosyltransferase regulatory subunit YP_002491.1 3109787 D 267671 CDS YP_002492.1 45658406 2772811 3110859..3112136 1 NC_005823.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 3112136 purA 2772811 purA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylosuccinate synthetase YP_002492.1 3110859 D 267671 CDS YP_002493.1 45658407 2772580 complement(3113788..3114624) 1 NC_005823.1 hypothetical protein 3114624 2772580 LIC12568 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002493.1 3113788 R 267671 CDS YP_002494.1 45658408 2770839 complement(3114656..3116551) 1 NC_005823.1 hypothetical protein 3116551 2770839 LIC12569 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002494.1 3114656 R 267671 CDS YP_002495.1 45658409 2770407 complement(3116548..3117897) 1 NC_005823.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 3117897 2770407 LIC12570 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 (dimethylallyl)adenosine tRNA methylthiotransferase YP_002495.1 3116548 R 267671 CDS YP_002496.1 45658410 2770701 3118595..3119239 1 NC_005823.1 hypothetical protein 3119239 2770701 LIC12572 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002496.1 3118595 D 267671 CDS YP_002497.1 45658411 2769884 3120448..3121620 1 NC_005823.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 3121620 sucC 2769884 sucC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 succinyl-CoA synthetase subunit beta YP_002497.1 3120448 D 267671 CDS YP_002498.1 45658412 2771096 3121633..3122508 1 NC_005823.1 succinyl-CoA synthetase subunit alpha 3122508 sucD 2771096 sucD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 succinyl-CoA synthetase subunit alpha YP_002498.1 3121633 D 267671 CDS YP_002499.1 45658413 2771898 3122795..3124372 1 NC_005823.1 hypothetical protein 3124372 2771898 LIC12575 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002499.1 3122795 D 267671 CDS YP_002500.1 45658414 2770875 3124394..3125827 1 NC_005823.1 hypothetical protein 3125827 2770875 LIC12576 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002500.1 3124394 D 267671 CDS YP_002501.1 45658415 2772002 3125866..3126108 1 NC_005823.1 hypothetical protein 3126108 2772002 LIC12577 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002501.1 3125866 D 267671 CDS YP_002502.2 304570500 2771331 3126121..3126969 1 NC_005823.1 hypothetical protein 3126969 2771331 LIC12578 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002502.2 3126121 D 267671 CDS YP_002503.1 45658417 2770971 3127022..3128218 1 NC_005823.1 lipid-a-disaccharide synthase protein 3128218 lpxB 2770971 lpxB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipid-a-disaccharide synthase protein YP_002503.1 3127022 D 267671 CDS YP_002504.1 45658418 2770907 3128806..3129012 1 NC_005823.1 hypothetical protein 3129012 2770907 LIC12580 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002504.1 3128806 D 267671 CDS YP_002505.1 45658419 2772576 complement(3129050..3129532) 1 NC_005823.1 hypothetical protein 3129532 2772576 LIC12581 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002505.1 3129050 R 267671 CDS YP_002506.1 45658420 2772444 3129565..3129915 1 NC_005823.1 ArsR family transcriptional regulator 3129915 2772444 LIC12582 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ArsR family transcriptional regulator YP_002506.1 3129565 D 267671 CDS YP_002507.1 45658421 2770222 complement(3130033..3130221) 1 NC_005823.1 hypothetical protein 3130221 2770222 LIC12583 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002507.1 3130033 R 267671 CDS YP_002508.1 45658422 2771633 complement(3130224..3130478) 1 NC_005823.1 hypothetical protein 3130478 2771633 LIC12584 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002508.1 3130224 R 267671 CDS YP_002509.1 45658423 2771270 complement(3131007..3131411) 1 NC_005823.1 hypothetical protein 3131411 2771270 LIC12585 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002509.1 3131007 R 267671 CDS YP_002510.1 45658424 2770470 complement(3131381..3133573) 1 NC_005823.1 hypothetical protein 3133573 2770470 LIC12586 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002510.1 3131381 R 267671 CDS YP_002511.1 45658425 2770586 complement(3133591..3134241) 1 NC_005823.1 lipoprotein 3134241 2770586 LIC12587 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002511.1 3133591 R 267671 CDS YP_002512.1 45658426 2771684 complement(3134244..3136268) 1 NC_005823.1 ATP-dependent DNA helicase 3136268 2771684 LIC12588 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent DNA helicase YP_002512.1 3134244 R 267671 CDS YP_002513.1 45658427 2770277 3136774..3137352 1 NC_005823.1 hypothetical protein 3137352 2770277 LIC12589 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002513.1 3136774 D 267671 CDS YP_002514.1 45658428 2770368 3137354..3138610 1 NC_005823.1 major facilitator superfamily; identified by sequence similarity; ORF located using Blastx/Glimmer; drug proton antiporter 3138610 2770368 LIC12590 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 drug proton antiporter YP_002514.1 3137354 D 267671 CDS YP_002515.1 45658429 2772666 3138750..3141404 1 NC_005823.1 aminopeptidase N 3141404 pepN 2772666 pepN Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aminopeptidase N YP_002515.1 3138750 D 267671 CDS YP_002516.1 45658430 2771673 3141401..3142132 1 NC_005823.1 hypothetical protein 3142132 2771673 LIC12592 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002516.1 3141401 D 267671 CDS YP_002517.1 45658431 2772770 3143092..3143379 1 NC_005823.1 hypothetical protein 3143379 2772770 LIC12594 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002517.1 3143092 D 267671 CDS YP_002518.1 45658432 2772201 3144882..3145832 1 NC_005823.1 fumarylacetoacetate hydrolase family protein 3145832 2772201 LIC12595 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 fumarylacetoacetate hydrolase family protein YP_002518.1 3144882 D 267671 CDS YP_002519.1 45658433 2770991 3146570..3147097 1 NC_005823.1 hypothetical protein 3147097 2770991 LIC12596 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002519.1 3146570 D 267671 CDS YP_002520.1 45658434 2770342 3147209..3148294 1 NC_005823.1 hypothetical protein 3148294 2770342 LIC12597 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002520.1 3147209 D 267671 CDS YP_002521.1 45658435 2772798 3148923..3150257 1 NC_005823.1 adenylate/guanylate cyclase 3150257 2772798 LIC12598 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_002521.1 3148923 D 267671 CDS YP_002522.1 45658436 2772057 3150383..3151246 1 NC_005823.1 alpha/beta fold family hydrolase 3151246 2772057 LIC12599 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alpha/beta fold family hydrolase YP_002522.1 3150383 D 267671 CDS YP_002523.1 45658437 2770607 complement(3152254..3152985) 1 NC_005823.1 hypothetical protein 3152985 2770607 LIC12600 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002523.1 3152254 R 267671 CDS YP_002524.1 45658438 2769839 complement(3152985..3153905) 1 NC_005823.1 hypothetical protein 3153905 2769839 LIC12601 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002524.1 3152985 R 267671 CDS YP_002525.1 45658439 2770444 complement(3154020..3154895) 1 NC_005823.1 hypothetical protein 3154895 2770444 LIC12602 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002525.1 3154020 R 267671 CDS YP_002526.1 45658440 2770120 complement(3154892..3155167) 1 NC_005823.1 hypothetical protein 3155167 2770120 LIC12603 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002526.1 3154892 R 267671 CDS YP_002527.1 45658441 2770943 complement(3155164..3156138) 1 NC_005823.1 hypothetical protein 3156138 2770943 LIC12604 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002527.1 3155164 R 267671 CDS YP_002528.1 45658442 2770429 complement(3156135..3157352) 1 NC_005823.1 hypothetical protein 3157352 2770429 LIC12605 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002528.1 3156135 R 267671 CDS YP_002529.1 45658443 2770910 complement(3157349..3157693) 1 NC_005823.1 hypothetical protein 3157693 2770910 LIC12606 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002529.1 3157349 R 267671 CDS YP_002530.1 45658444 2772348 complement(3157690..3158403) 1 NC_005823.1 hypothetical protein 3158403 2772348 LIC12607 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002530.1 3157690 R 267671 CDS YP_002531.1 45658445 2769959 complement(3158370..3159188) 1 NC_005823.1 hypothetical protein 3159188 2769959 LIC12608 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002531.1 3158370 R 267671 CDS YP_002532.1 45658446 2772311 complement(3159185..3159523) 1 NC_005823.1 hypothetical protein 3159523 2772311 LIC12609 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002532.1 3159185 R 267671 CDS YP_002533.1 45658447 2771867 complement(3159541..3160152) 1 NC_005823.1 hypothetical protein 3160152 2771867 LIC12610 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002533.1 3159541 R 267671 CDS YP_002534.1 45658448 2770904 complement(3160149..3161969) 1 NC_005823.1 hypothetical protein 3161969 2770904 LIC12611 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002534.1 3160149 R 267671 CDS YP_002535.1 45658449 2772001 complement(3162015..3162233) 1 NC_005823.1 hypothetical protein 3162233 2772001 LIC12612 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002535.1 3162015 R 267671 CDS YP_002536.1 45658450 2770923 complement(3162277..3162660) 1 NC_005823.1 hypothetical protein 3162660 2770923 LIC12613 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002536.1 3162277 R 267671 CDS YP_002537.1 45658451 2770896 complement(3162657..3163067) 1 NC_005823.1 hypothetical protein 3163067 2770896 LIC12614 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002537.1 3162657 R 267671 CDS YP_002538.2 304570501 2772616 complement(3163081..3164460) 1 NC_005823.1 hypothetical protein 3164460 2772616 LIC12615 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002538.2 3163081 R 267671 CDS YP_002539.1 45658453 2770397 complement(3164457..3164981) 1 NC_005823.1 hypothetical protein 3164981 2770397 LIC12616 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002539.1 3164457 R 267671 CDS YP_002540.1 45658454 2772117 complement(3166560..3167276) 1 NC_005823.1 bifunctional enzyme; identified by sequence similarity; ORF located using Blastx/Glimmer; 4-diphosphocytidyl-2-methyl-D-erithritol synthase 3167276 ispD 2772117 ispD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 4-diphosphocytidyl-2-methyl-D-erithritol synthase YP_002540.1 3166560 R 267671 CDS YP_002541.1 45658455 2772778 complement(3167254..3168522) 1 NC_005823.1 diaminopimelate decarboxylase 3168522 lysA 2772778 lysA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 diaminopimelate decarboxylase YP_002541.1 3167254 R 267671 CDS YP_002542.1 45658456 2770745 3168598..3169674 1 NC_005823.1 hypothetical protein 3169674 2770745 LIC12619 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002542.1 3168598 D 267671 CDS YP_002543.1 45658457 2770848 3169681..3172164 1 NC_005823.1 penicillin-binding protein; membrane carboxypeptidase 3172164 2770848 LIC12620 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 membrane carboxypeptidase YP_002543.1 3169681 D 267671 CDS YP_002544.1 45658458 2770604 3172266..3172676 1 NC_005823.1 hypothetical protein 3172676 2770604 LIC12621 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002544.1 3172266 D 267671 CDS YP_002545.1 45658459 2771226 3172732..3173850 1 NC_005823.1 membrane metalloendopeptidase 3173850 2771226 LIC12622 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 membrane metalloendopeptidase YP_002545.1 3172732 D 267671 CDS YP_002546.1 45658460 2772920 3174227..3174433 1 NC_005823.1 hypothetical protein 3174433 2772920 LIC12623 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002546.1 3174227 D 267671 CDS YP_002547.1 45658461 2772864 3174754..3175836 1 NC_005823.1 hypothetical protein 3175836 2772864 LIC12624 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002547.1 3174754 D 267671 CDS YP_002548.1 45658462 2772426 3175940..3176614 1 NC_005823.1 hypothetical protein 3176614 2772426 LIC12625 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002548.1 3175940 D 267671 CDS YP_002549.1 45658463 2772890 complement(3176681..3176881) 1 NC_005823.1 hypothetical protein 3176881 2772890 LIC12626 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002549.1 3176681 R 267671 CDS YP_002550.1 45658464 2770711 3177509..3178888 1 NC_005823.1 histidine kinase response regulator hybrid protein 3178888 2770711 LIC12627 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase response regulator hybrid protein YP_002550.1 3177509 D 267671 CDS YP_002551.1 45658465 2772464 complement(3180523..3180753) 1 NC_005823.1 hypothetical protein 3180753 2772464 LIC12628 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002551.1 3180523 R 267671 CDS YP_002552.2 304570502 2770613 3180828..3181655 1 NC_005823.1 enoyl-CoA hydratase 3181655 ech3 2770613 ech3 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 enoyl-CoA hydratase YP_002552.2 3180828 D 267671 CDS YP_002553.1 45658467 2770908 3181948..3182796 1 NC_005823.1 hypothetical protein 3182796 2770908 LIC12630 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002553.1 3181948 D 267671 CDS YP_002554.1 45658468 2770272 3183448..3185319 1 NC_005823.1 sphingomyelinase; hemolysin 3185319 2770272 LIC12631 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hemolysin YP_002554.1 3183448 D 267671 CDS YP_002555.1 45658469 2772092 3186233..3188023 1 NC_005823.1 sphingomyelinase; hemolysin 3188023 2772092 LIC12632 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hemolysin YP_002555.1 3186233 D 267671 CDS YP_002556.1 45658470 2772703 complement(3188787..3189812) 1 NC_005823.1 hypothetical protein 3189812 2772703 LIC12633 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002556.1 3188787 R 267671 CDS YP_002557.1 45658471 2770733 complement(3189821..3193198) 1 NC_005823.1 hypothetical protein 3193198 2770733 LIC12634 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002557.1 3189821 R 267671 CDS YP_002558.1 45658472 2772299 3193696..3194859 1 NC_005823.1 hypothetical protein 3194859 2772299 LIC12635 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002558.1 3193696 D 267671 CDS YP_002559.1 45658473 2771799 3195007..3196455 1 NC_005823.1 transcription termination factor; An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 3196455 rho 2771799 rho Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transcription termination factor Rho YP_002559.1 3195007 D 267671 CDS YP_002560.1 45658474 2770843 3196476..3196679 1 NC_005823.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 3196679 rpmE 2770843 rpmE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L31 YP_002560.1 3196476 D 267671 CDS YP_002561.1 45658475 2772894 3196738..3197529 1 NC_005823.1 internal repeat sequences detected; contains Pentapeptide repeats (8 copies) by pfam-hmmr; hypothetical protein 3197529 2772894 LIC12638 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002561.1 3196738 D 267671 CDS YP_002562.1 45658476 2772896 3197526..3197714 1 NC_005823.1 hypothetical protein 3197714 2772896 LIC12639 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002562.1 3197526 D 267671 CDS YP_002563.1 45658477 2772910 3198026..3198859 1 NC_005823.1 internal repeat sequences detected; contains TPR domain as detected by pfam-hmmr; hypothetical protein 3198859 2772910 LIC12640 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002563.1 3198026 D 267671 CDS YP_002564.1 45658478 2772926 3198856..3201024 1 NC_005823.1 hypothetical protein 3201024 2772926 LIC12641 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002564.1 3198856 D 267671 CDS YP_002565.1 45658479 2772929 3201187..3201645 1 NC_005823.1 hypothetical protein 3201645 2772929 LIC12642 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002565.1 3201187 D 267671 CDS YP_002566.1 45658480 2772932 3201895..3202320 1 NC_005823.1 hypothetical protein 3202320 2772932 LIC12643 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002566.1 3201895 D 267671 CDS YP_002567.1 45658481 2772945 complement(3202494..3203498) 1 NC_005823.1 hypothetical protein 3203498 2772945 LIC12644 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002567.1 3202494 R 267671 CDS YP_002568.1 45658482 2772943 complement(3204530..3206089) 1 NC_005823.1 hypothetical protein 3206089 2772943 LIC12645 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002568.1 3204530 R 267671 CDS YP_002569.1 45658483 2769823 complement(3206079..3208835) 1 NC_005823.1 penicillin-binding protein; transmembrane protein; identified by sequence similarity; ORF located using Blastx/Glimmer; peptidoglycan synthetase; membrane carboxypeptidase 3208835 2769823 LIC12646 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 membrane carboxypeptidase YP_002569.1 3206079 R 267671 CDS YP_002570.1 45658484 2769653 complement(3208872..3209768) 1 NC_005823.1 hypothetical protein 3209768 2769653 LIC12647 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002570.1 3208872 R 267671 CDS YP_002571.1 45658485 2769606 complement(3210464..3211033) 1 NC_005823.1 glutathione peroxidase 3211033 btuE 2769606 btuE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutathione peroxidase YP_002571.1 3210464 R 267671 CDS YP_002572.1 45658486 2769569 complement(3211812..3213356) 1 NC_005823.1 hypothetical protein 3213356 2769569 LIC12649 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002572.1 3211812 R 267671 CDS YP_002573.1 45658487 2769731 3215164..3215691 1 NC_005823.1 hypothetical protein 3215691 2769731 LIC12650 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002573.1 3215164 D 267671 CDS YP_002574.1 45658488 2769633 3215932..3216666 1 NC_005823.1 hypothetical protein 3216666 2769633 LIC12651 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002574.1 3215932 D 267671 CDS YP_002575.1 45658489 2769648 3216884..3217993 1 NC_005823.1 hypothetical protein 3217993 2769648 LIC12652 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002575.1 3216884 D 267671 CDS YP_002576.1 45658490 2769616 complement(3218264..3218473) 1 NC_005823.1 hypothetical protein 3218473 2769616 LIC12653 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002576.1 3218264 R 267671 CDS YP_002577.1 45658491 2772942 3218605..3219234 1 NC_005823.1 LexA family transcriptional repressor 3219234 2772942 LIC12654 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 LexA family transcriptional repressor YP_002577.1 3218605 D 267671 CDS YP_002578.1 45658492 2769607 3219441..3220364 1 NC_005823.1 hypothetical protein 3220364 2769607 LIC12655 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002578.1 3219441 D 267671 CDS YP_002579.1 45658493 2769733 3220623..3221312 1 NC_005823.1 hypothetical protein 3221312 2769733 LIC12656 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002579.1 3220623 D 267671 CDS YP_002580.1 45658494 2769822 3221299..3221844 1 NC_005823.1 hypothetical protein 3221844 2769822 LIC12657 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002580.1 3221299 D 267671 CDS YP_002581.1 45658495 2769654 3221940..3222371 1 NC_005823.1 hypothetical protein 3222371 2769654 LIC12658 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002581.1 3221940 D 267671 CDS YP_002582.1 45658496 2769629 3222663..3222893 1 NC_005823.1 virulence-associated protein 3222893 vapB 2769629 vapB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 virulence-associated protein YP_002582.1 3222663 D 267671 CDS YP_002583.1 45658497 2769615 3222893..3223291 1 NC_005823.1 DNA binding domain-containing protein 3223291 vapC 2769615 vapC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA binding domain-containing protein YP_002583.1 3222893 D 267671 CDS YP_002584.1 45658498 2769524 3223389..3223691 1 NC_005823.1 hypothetical protein 3223691 2769524 LIC12661 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002584.1 3223389 D 267671 CDS YP_002585.1 45658499 2769587 3223746..3224045 1 NC_005823.1 IS1500 transposase 3224045 2769587 LIC12662 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 IS1500 transposase YP_002585.1 3223746 D 267671 CDS YP_002586.1 45658500 2769528 3224948..3225175 1 NC_005823.1 hypothetical protein 3225175 2769528 LIC12664 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002586.1 3224948 D 267671 CDS YP_002587.1 45658501 2772950 3225318..3226394 1 NC_005823.1 hypothetical protein 3226394 2772950 LIC12665 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002587.1 3225318 D 267671 CDS YP_002588.1 45658502 2772952 3226395..3226853 1 NC_005823.1 GNAT family; identified by sequence similarity; ORF located using Blastx/Glimmer; acetyltransferase 3226853 2772952 LIC12666 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyltransferase YP_002588.1 3226395 D 267671 CDS YP_002589.1 45658503 2771026 complement(3227070..3227930) 1 NC_005823.1 lipoprotein 3227930 2771026 LIC12667 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002589.1 3227070 R 267671 CDS YP_002590.1 45658504 2772934 complement(3228471..3229238) 1 NC_005823.1 hypothetical protein 3229238 2772934 LIC12668 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002590.1 3228471 R 267671 CDS YP_002591.1 45658505 2772928 complement(3229238..3230053) 1 NC_005823.1 hypothetical protein 3230053 2772928 LIC12669 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002591.1 3229238 R 267671 CDS YP_002592.1 45658506 2772898 complement(3231623..3233872) 1 NC_005823.1 adenylate/guanylate cyclase 3233872 cyaA 2772898 cyaA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_002592.1 3231623 R 267671 CDS YP_002593.1 45658507 2770689 3234020..3235030 1 NC_005823.1 small conductance mechanosensitive ion channel 3235030 2770689 LIC12671 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 small conductance mechanosensitive ion channel YP_002593.1 3234020 D 267671 CDS YP_002594.1 45658508 2770974 3235079..3235915 1 NC_005823.1 hypothetical protein 3235915 2770974 LIC12672 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002594.1 3235079 D 267671 CDS YP_002595.1 45658509 2770686 complement(3235908..3236606) 1 NC_005823.1 hypothetical protein 3236606 2770686 LIC12673 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002595.1 3235908 R 267671 CDS YP_002596.1 45658510 2771376 3236672..3237136 1 NC_005823.1 hypothetical protein 3237136 2771376 LIC12674 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002596.1 3236672 D 267671 CDS YP_002597.1 45658511 2772915 3237880..3239025 1 NC_005823.1 hypothetical protein 3239025 2772915 LIC12675 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002597.1 3237880 D 267671 CDS YP_002598.1 45658512 2772924 3239403..3241376 1 NC_005823.1 hypothetical protein 3241376 2772924 LIC12676 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002598.1 3239403 D 267671 CDS YP_002599.1 45658513 2771210 3241479..3242984 1 NC_005823.1 ATP-dependent DNA ligase 3242984 2771210 LIC12677 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent DNA ligase YP_002599.1 3241479 D 267671 CDS YP_002600.1 45658514 2771444 3243113..3245239 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 3245239 2771444 LIC12678 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002600.1 3243113 D 267671 CDS YP_002601.1 45658515 2771992 3246449..3247996 1 NC_005823.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 3247996 thiC 2771992 thiC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thiamine biosynthesis protein ThiC YP_002601.1 3246449 D 267671 CDS YP_002602.1 45658516 2771874 complement(3248599..3250026) 1 NC_005823.1 FimH-like protein 3250026 2771874 LIC12680 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 FimH-like protein YP_002602.1 3248599 R 267671 CDS YP_002603.1 45658517 2770040 3250392..3250712 1 NC_005823.1 hypothetical protein 3250712 2770040 LIC12681 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002603.1 3250392 D 267671 CDS YP_002604.1 45658518 2771735 complement(3252109..3252972) 1 NC_005823.1 3-oxoacyl-ACP 3252972 2771735 LIC12682 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-oxoacyl-ACP YP_002604.1 3252109 R 267671 CDS YP_002605.1 45658519 2770868 complement(3252976..3253737) 1 NC_005823.1 ABC transporter 3253737 2770868 LIC12683 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter YP_002605.1 3252976 R 267671 CDS YP_002606.1 45658520 2770532 complement(3253734..3254726) 1 NC_005823.1 ABC transporter ATP-binding protein 3254726 2770532 LIC12684 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_002606.1 3253734 R 267671 CDS YP_002607.1 45658521 2772590 complement(3255040..3256893) 1 NC_005823.1 exodeoxyribonuclease v subunit alpha 3256893 recD 2772590 recD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 exodeoxyribonuclease v subunit alpha YP_002607.1 3255040 R 267671 CDS YP_002608.1 45658522 2772343 complement(3256875..3259976) 1 NC_005823.1 exodeoxyribonuclease V subunit beta 3259976 recB 2772343 recB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 exodeoxyribonuclease V subunit beta YP_002608.1 3256875 R 267671 CDS YP_002609.1 45658523 2770852 complement(3260005..3263403) 1 NC_005823.1 exodeoxyribonuclease v subunit gamma 3263403 recC 2770852 recC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 exodeoxyribonuclease v subunit gamma YP_002609.1 3260005 R 267671 CDS YP_002610.1 45658524 2770953 3263508..3264956 1 NC_005823.1 ATP-dependent DNA helicase 3264956 2770953 LIC12689 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent DNA helicase YP_002610.1 3263508 D 267671 CDS YP_002611.1 45658525 2769889 3265665..3268190 1 NC_005823.1 lipoprotein 3268190 2769889 LIC12690 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002611.1 3265665 D 267671 CDS YP_002612.1 45658526 2772431 3268533..3269075 1 NC_005823.1 hypothetical protein 3269075 2772431 LIC12691 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002612.1 3268533 D 267671 CDS YP_002613.1 45658527 2772284 complement(3270352..3272502) 1 NC_005823.1 hypothetical protein 3272502 2772284 LIC12692 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002613.1 3270352 R 267671 CDS YP_002614.1 45658528 2769929 3272518..3274191 1 NC_005823.1 hypothetical protein 3274191 2769929 LIC12693 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002614.1 3272518 D 267671 CDS YP_002615.1 45658529 2769855 complement(3275177..3279673) 1 NC_005823.1 glutamate synthase (NADPH) subunit alpha precursor 3279673 2769855 LIC12694 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutamate synthase (NADPH) subunit alpha precursor YP_002615.1 3275177 R 267671 CDS YP_002616.1 45658530 2771556 complement(3280095..3281420) 1 NC_005823.1 hypothetical protein 3281420 2771556 LIC12695 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002616.1 3280095 R 267671 CDS YP_002617.1 45658531 2770905 complement(3282304..3283023) 1 NC_005823.1 hypothetical protein 3283023 2770905 LIC12696 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002617.1 3282304 R 267671 CDS YP_002618.1 45658532 2772644 complement(3283080..3283268) 1 NC_005823.1 hypothetical protein 3283268 2772644 LIC12697 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002618.1 3283080 R 267671 CDS YP_002619.1 45658533 2770595 complement(3283504..3283815) 1 NC_005823.1 hypothetical protein 3283815 2770595 LIC12698 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002619.1 3283504 R 267671 CDS YP_002620.1 45658534 2770648 complement(3283987..3284325) 1 NC_005823.1 hypothetical protein 3284325 2770648 LIC12699 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002620.1 3283987 R 267671 CDS YP_002621.1 45658535 2770375 complement(3285093..3286379) 1 NC_005823.1 metalloprotease 3286379 pqqL 2770375 pqqL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 metalloprotease YP_002621.1 3285093 R 267671 CDS YP_002622.1 45658536 2772003 complement(3286398..3288494) 1 NC_005823.1 polynucleotide phosphorylase/polyadenylase 3288494 pnpA 2772003 pnpA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 polynucleotide phosphorylase/polyadenylase YP_002622.1 3286398 R 267671 CDS YP_002623.1 45658537 2770262 complement(3288506..3288772) 1 NC_005823.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 3288772 rpsO 2770262 rpsO Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S15 YP_002623.1 3288506 R 267671 CDS YP_002624.2 161621773 2771024 complement(3288824..3289753) 1 NC_005823.1 tRNA pseudouridine synthase B 3289753 truB 2771024 truB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tRNA pseudouridine synthase B YP_002624.2 3288824 R 267671 CDS YP_002625.1 45658539 2770727 complement(3289710..3290063) 1 NC_005823.1 ribosomal-binding factor A 3290063 rbfA 2770727 rbfA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribosomal-binding factor A YP_002625.1 3289710 R 267671 CDS YP_002626.1 45658540 2770599 complement(3290073..3292748) 1 NC_005823.1 GTPase; Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 3292748 infB 2770599 infB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 translation initiation factor IF-2 YP_002626.1 3290073 R 267671 CDS YP_002627.1 45658541 2770400 complement(3292762..3294144) 1 NC_005823.1 transcription termination factor; modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 3294144 nusA 2770400 nusA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transcription elongation factor NusA YP_002627.1 3292762 R 267671 CDS YP_002628.1 45658542 2772404 complement(3294146..3294634) 1 NC_005823.1 hypothetical protein 3294634 2772404 LIC12707 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002628.1 3294146 R 267671 CDS YP_002629.1 45658543 2771888 3294811..3295989 1 NC_005823.1 hypothetical protein 3295989 2771888 LIC12708 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002629.1 3294811 D 267671 CDS YP_002630.1 45658544 2772724 3295980..3297734 1 NC_005823.1 hypothetical protein 3297734 2772724 LIC12709 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002630.1 3295980 D 267671 CDS YP_002631.1 45658545 2770750 3297736..3298347 1 NC_005823.1 hypothetical protein 3298347 2770750 LIC12710 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002631.1 3297736 D 267671 CDS YP_002632.1 45658546 2770276 3298350..3298778 1 NC_005823.1 N-acetylglutamate synthase/acetyltransferase 3298778 argA 2770276 argA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 N-acetylglutamate synthase/acetyltransferase YP_002632.1 3298350 D 267671 CDS YP_002633.1 45658547 2770271 3298986..3299219 1 NC_005823.1 hypothetical protein 3299219 2770271 LIC12712 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002633.1 3298986 D 267671 CDS YP_002634.1 45658548 2772696 3299221..3299619 1 NC_005823.1 hypothetical protein 3299619 2772696 LIC12713 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002634.1 3299221 D 267671 CDS YP_002635.1 45658549 2771058 3299735..3300841 1 NC_005823.1 hypothetical protein 3300841 2771058 LIC12714 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002635.1 3299735 D 267671 CDS YP_002636.1 45658550 2771020 complement(3302048..3303964) 1 NC_005823.1 hypothetical protein 3303964 2771020 LIC12715 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002636.1 3302048 R 267671 CDS YP_002637.1 45658551 2770566 complement(3305680..3306618) 1 NC_005823.1 hypothetical protein 3306618 2770566 LIC12716 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002637.1 3305680 R 267671 CDS YP_002638.1 45658552 2770835 3306857..3308254 1 NC_005823.1 4-hydroxybenzoate transporter transmembrane protein 3308254 proP 2770835 proP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 4-hydroxybenzoate transporter transmembrane protein YP_002638.1 3306857 D 267671 CDS YP_002639.1 45658553 2770784 3308260..3308964 1 NC_005823.1 enolase-phosphatase E-1 3308964 2770784 LIC12718 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 enolase-phosphatase E-1 YP_002639.1 3308260 D 267671 CDS YP_002640.1 45658554 2772592 3310286..3311527 1 NC_005823.1 hypothetical protein 3311527 2772592 LIC12719 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002640.1 3310286 D 267671 CDS YP_002641.1 45658555 2771028 3312554..3312733 1 NC_005823.1 IS1533 transposase 3312733 2771028 LIC12721 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 IS1533 transposase YP_002641.1 3312554 D 267671 CDS YP_002642.1 45658556 2770930 3312795..3313166 1 NC_005823.1 IS1533 transposase 3313166 2770930 LIC12722 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 IS1533 transposase YP_002642.1 3312795 D 267671 CDS YP_002643.1 45658557 2769966 complement(3314402..3315688) 1 NC_005823.1 hypothetical protein 3315688 2769966 LIC12723 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002643.1 3314402 R 267671 CDS YP_002644.1 45658558 2770793 3316322..3316849 1 NC_005823.1 hypothetical protein 3316849 2770793 LIC12724 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002644.1 3316322 D 267671 CDS YP_002645.1 45658559 2769902 3316849..3317649 1 NC_005823.1 3-hydroxybutyryl-CoA dehydratase 3317649 2769902 LIC12725 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-hydroxybutyryl-CoA dehydratase YP_002645.1 3316849 D 267671 CDS YP_002646.1 45658560 2772034 complement(3318748..3319953) 1 NC_005823.1 hypothetical protein 3319953 2772034 LIC12726 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002646.1 3318748 R 267671 CDS YP_002647.1 45658561 2771420 3320385..3321326 1 NC_005823.1 acetoin-histone deacetylase 3321326 2771420 LIC12727 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetoin-histone deacetylase YP_002647.1 3320385 D 267671 CDS YP_002648.1 45658562 2771839 3322228..3322812 1 NC_005823.1 hypothetical protein 3322812 2771839 LIC12728 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002648.1 3322228 D 267671 CDS YP_002649.1 45658563 2770879 3322857..3323060 1 NC_005823.1 hypothetical protein 3323060 2770879 LIC12729 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002649.1 3322857 D 267671 CDS YP_002650.1 45658564 2770269 3323552..3325582 1 NC_005823.1 internal repeat sequences detected; contains NHL repeat as detected by pfam-hmmr; hypothetical protein 3325582 2770269 LIC12730 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002650.1 3323552 D 267671 CDS YP_002651.1 45658565 2772559 3325579..3327576 1 NC_005823.1 internal repeat sequences detected; contains TPR domain as detected by pfam-hmmr; hypothetical protein 3327576 2772559 LIC12731 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002651.1 3325579 D 267671 CDS YP_002652.1 45658566 2771910 complement(3327573..3328199) 1 NC_005823.1 hypothetical protein 3328199 2771910 LIC12732 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002652.1 3327573 R 267671 CDS YP_002653.1 45658567 2770986 complement(3329123..3329569) 1 NC_005823.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 3329569 mgsA 2770986 mgsA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methylglyoxal synthase YP_002653.1 3329123 R 267671 CDS YP_002654.1 45658568 2770906 3329702..3330496 1 NC_005823.1 hypothetical protein 3330496 2770906 LIC12734 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002654.1 3329702 D 267671 CDS YP_002655.1 45658569 2770862 3330895..3331314 1 NC_005823.1 hypothetical protein 3331314 2770862 LIC12735 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002655.1 3330895 D 267671 CDS YP_002656.1 45658570 2770680 complement(3331889..3332683) 1 NC_005823.1 lipoprotein 3332683 2770680 LIC12736 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002656.1 3331889 R 267671 CDS YP_002657.1 45658571 2770389 complement(3333389..3335020) 1 NC_005823.1 site-specific modification DNA-methyltransferase 3335020 2770389 LIC12737 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 site-specific modification DNA-methyltransferase YP_002657.1 3333389 R 267671 CDS YP_002658.1 45658572 2770401 complement(3336564..3337019) 1 NC_005823.1 MarR family transcriptional regulator 3337019 2770401 LIC12738 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 MarR family transcriptional regulator YP_002658.1 3336564 R 267671 CDS YP_002659.1 45658573 2772162 complement(3337050..3337514) 1 NC_005823.1 MaoC family protein 3337514 2772162 LIC12739 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 MaoC family protein YP_002659.1 3337050 R 267671 CDS YP_002660.1 45658574 2770077 complement(3337527..3337928) 1 NC_005823.1 hypothetical protein 3337928 2770077 LIC12740 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002660.1 3337527 R 267671 CDS YP_002661.1 45658575 2770122 3338493..3338927 1 NC_005823.1 NADH dehydrogenase subunit I A 3338927 nuoA 2770122 nuoA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH dehydrogenase subunit I A YP_002661.1 3338493 D 267671 CDS YP_002662.1 45658576 2770553 3338918..3339478 1 NC_005823.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 3339478 nuoB 2770553 nuoB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH dehydrogenase subunit B YP_002662.1 3338918 D 267671 CDS YP_002663.1 45658577 2770376 3339475..3340011 1 NC_005823.1 NADH dehydrogenase subunit I C 3340011 nuoC 2770376 nuoC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH dehydrogenase subunit I C YP_002663.1 3339475 D 267671 CDS YP_002664.1 45658578 2770622 3340013..3341230 1 NC_005823.1 NADH dehydrogenase subunit I D 3341230 nuoD2 2770622 nuoD2 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH dehydrogenase subunit I D YP_002664.1 3340013 D 267671 CDS YP_002665.1 45658579 2770724 3341224..3341709 1 NC_005823.1 NADH dehydrogenase subunit I E 3341709 nuoE 2770724 nuoE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH dehydrogenase subunit I E YP_002665.1 3341224 D 267671 CDS YP_002666.1 45658580 2769834 3341725..3343056 1 NC_005823.1 NADH dehydrogenase subunit I F 3343056 nuoF 2769834 nuoF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH dehydrogenase subunit I F YP_002666.1 3341725 D 267671 CDS YP_002667.1 45658581 2770386 3343053..3344093 1 NC_005823.1 NADH dehydrogenase subunit I H 3344093 nuoH 2770386 nuoH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH dehydrogenase subunit I H YP_002667.1 3343053 D 267671 CDS YP_002668.1 45658582 2770488 3344107..3344808 1 NC_005823.1 NADH dehydrogenase I subunit J 3344808 nuoJ 2770488 nuoJ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH dehydrogenase I subunit J YP_002668.1 3344107 D 267671 CDS YP_002669.1 45658583 2770073 3344805..3345125 1 NC_005823.1 NADH dehydrogenase I subunit K 3345125 nuoK 2770073 nuoK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH dehydrogenase I subunit K YP_002669.1 3344805 D 267671 CDS YP_002670.1 45658584 2770591 3345130..3347079 1 NC_005823.1 NADH dehydrogenase I subunit L 3347079 nuoL 2770591 nuoL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH dehydrogenase I subunit L YP_002670.1 3345130 D 267671 CDS YP_002671.1 45658585 2769937 3347081..3348769 1 NC_005823.1 NADH dehydrogenase I subunit M 3348769 nuoM 2769937 nuoM Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH dehydrogenase I subunit M YP_002671.1 3347081 D 267671 CDS YP_002672.1 45658586 2771394 3348766..3350304 1 NC_005823.1 NADH dehydrogenase I subunit N 3350304 nuoN 2771394 nuoN Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH dehydrogenase I subunit N YP_002672.1 3348766 D 267671 CDS YP_002673.1 45658587 2770756 complement(3351116..3351556) 1 NC_005823.1 hypothetical protein 3351556 2770756 LIC12753 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002673.1 3351116 R 267671 CDS YP_002674.1 45658588 2770921 complement(3351610..3351960) 1 NC_005823.1 hypothetical protein 3351960 2770921 LIC12754 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002674.1 3351610 R 267671 CDS YP_002675.1 45658589 2771495 3352896..3353366 1 NC_005823.1 hypothetical protein 3353366 2771495 LIC12755 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002675.1 3352896 D 267671 CDS YP_002676.1 45658590 2770238 complement(3353542..3354594) 1 NC_005823.1 DshA 3354594 dshA 2770238 dshA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DshA YP_002676.1 3353542 R 267671 CDS YP_002677.1 45658591 2770778 complement(3354605..3355147) 1 NC_005823.1 RNA polymerase ECF-type sigma factor 3355147 2770778 LIC12757 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA polymerase ECF-type sigma factor YP_002677.1 3354605 R 267671 CDS YP_002678.1 45658592 2771949 3355124..3356104 1 NC_005823.1 hypothetical protein 3356104 hsa 2771949 hsa Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002678.1 3355124 D 267671 CDS YP_002679.1 45658593 2772087 complement(3356953..3358224) 1 NC_005823.1 contains leucine-rich repeats; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 3358224 2772087 LIC12759 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002679.1 3356953 R 267671 CDS YP_002680.1 45658594 2770537 3359762..3362428 1 NC_005823.1 collagenase precursor 3362428 2770537 LIC12760 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 collagenase precursor YP_002680.1 3359762 D 267671 CDS YP_002681.1 45658595 2772857 complement(3363305..3364795) 1 NC_005823.1 aldehyde dehydrogenase 3364795 alkH 2772857 alkH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aldehyde dehydrogenase YP_002681.1 3363305 R 267671 CDS YP_002682.1 45658596 2770898 3365976..3367502 1 NC_005823.1 hypothetical protein 3367502 2770898 LIC12762 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002682.1 3365976 D 267671 CDS YP_002683.1 45658597 2770800 complement(3368749..3369063) 1 NC_005823.1 hypothetical protein 3369063 2770800 LIC12763 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002683.1 3368749 R 267671 CDS YP_002684.1 45658598 2769992 complement(3369098..3370780) 1 NC_005823.1 valine sensitive; identified by sequence similarity; ORF located using Blastx/Glimmer; acetolactate synthase I large subunit 3370780 ilvB 2769992 ilvB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetolactate synthase I large subunit YP_002684.1 3369098 R 267671 CDS YP_002685.1 45658599 2770792 3371458..3371973 1 NC_005823.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 3371973 tpx 2770792 tpx Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thiol peroxidase YP_002685.1 3371458 D 267671 CDS YP_002686.1 45658600 2769971 complement(3372331..3372735) 1 NC_005823.1 anti-sigma factor antagonist 3372735 2769971 LIC12766 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_002686.1 3372331 R 267671 CDS YP_002687.1 45658601 2770390 complement(3372725..3372964) 1 NC_005823.1 hypothetical protein 3372964 2770390 LIC12767 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002687.1 3372725 R 267671 CDS YP_002688.1 45658602 2769588 complement(3375244..3375432) 1 NC_005823.1 hypothetical protein 3375432 2769588 LIC12769 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002688.1 3375244 R 267671 CDS YP_002689.1 45658603 2769981 complement(3376748..3377347) 1 NC_005823.1 nicotinate-nucleotide adenylyltransferase 3377347 nadD 2769981 nadD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 nicotinate-nucleotide adenylyltransferase YP_002689.1 3376748 R 267671 CDS YP_002690.1 45658604 2770404 complement(3377351..3378601) 1 NC_005823.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 3378601 proA 2770404 proA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 gamma-glutamyl phosphate reductase YP_002690.1 3377351 R 267671 CDS YP_002691.1 45658605 2770261 complement(3378598..3379470) 1 NC_005823.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 3379470 proB 2770261 proB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 gamma-glutamyl kinase YP_002691.1 3378598 R 267671 CDS YP_002692.1 45658606 2770003 complement(3379484..3380554) 1 NC_005823.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 3380554 obgE 2770003 obgE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GTPase ObgE YP_002692.1 3379484 R 267671 CDS YP_002693.1 45658607 2770186 complement(3380669..3380923) 1 NC_005823.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 3380923 rpmA 2770186 rpmA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L27 YP_002693.1 3380669 R 267671 CDS YP_002694.1 45658608 2771344 complement(3380913..3381239) 1 NC_005823.1 hypothetical protein 3381239 2771344 LIC12775 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002694.1 3380913 R 267671 CDS YP_002695.1 45658609 2770367 complement(3381236..3381550) 1 NC_005823.1 50S ribosomal protein L21 3381550 rplU 2770367 rplU Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L21 YP_002695.1 3381236 R 267671 CDS YP_002696.1 45658610 2770753 complement(3383423..3383722) 1 NC_005823.1 hypothetical protein 3383722 2770753 LIC12779 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002696.1 3383423 R 267671 CDS YP_002697.1 45658611 2769954 complement(3383986..3384846) 1 NC_005823.1 internal repeat sequences detected; contains 3-demethylubiquinone-9 3-methyltransferase domain as detected by pfam-hmmr; hypothetical protein 3384846 2769954 LIC12780 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002697.1 3383986 R 267671 CDS YP_002698.1 45658612 2769847 complement(3384911..3385825) 1 NC_005823.1 hypothetical protein 3385825 2769847 LIC12781 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002698.1 3384911 R 267671 CDS YP_002699.1 45658613 2770941 complement(3385822..3386718) 1 NC_005823.1 hydroxymethylglutaryl-CoA lyase 3386718 2770941 LIC12782 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hydroxymethylglutaryl-CoA lyase YP_002699.1 3385822 R 267671 CDS YP_002700.1 45658614 2770027 complement(3387738..3389474) 1 NC_005823.1 dolichyl-phosphate-mannose-protein mannosyltransferase 3389474 2770027 LIC12783 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dolichyl-phosphate-mannose-protein mannosyltransferase YP_002700.1 3387738 R 267671 CDS YP_002701.1 45658615 2770669 complement(3389489..3389773) 1 NC_005823.1 lipoprotein 3389773 2770669 LIC12784 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002701.1 3389489 R 267671 CDS YP_002702.1 45658616 2770467 complement(3389804..3390865) 1 NC_005823.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 3390865 2770467 LIC12785 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribosomal RNA large subunit methyltransferase N YP_002702.1 3389804 R 267671 CDS YP_002703.1 45658617 2770882 complement(3391956..3392714) 1 NC_005823.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphat; indole-3-glycerol-phosphate synthase 3392714 trpC 2770882 trpC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 indole-3-glycerol-phosphate synthase YP_002703.1 3391956 R 267671 CDS YP_002704.1 45658618 2770885 complement(3392721..3393053) 1 NC_005823.1 anti-sigma factor antagonist 3393053 2770885 LIC12787 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_002704.1 3392721 R 267671 CDS YP_002705.1 45658619 2772440 3393136..3394527 1 NC_005823.1 UDP-n-acetylmuramoylalanine--d-glutamate ligase 3394527 murD 2772440 murD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-n-acetylmuramoylalanine--d-glutamate ligase YP_002705.1 3393136 D 267671 CDS YP_002706.1 45658620 2770728 3395105..3395323 1 NC_005823.1 hypothetical protein 3395323 2770728 LIC12789 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002706.1 3395105 D 267671 CDS YP_002707.1 45658621 2770168 3396090..3396344 1 NC_005823.1 hypothetical protein 3396344 2770168 LIC12790 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002707.1 3396090 D 267671 CDS YP_002708.1 45658622 2772059 3396530..3398425 1 NC_005823.1 hypothetical protein 3398425 2772059 LIC12791 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002708.1 3396530 D 267671 CDS YP_002709.1 45658623 2772324 complement(3399054..3399827) 1 NC_005823.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 3399827 2772324 LIC12792 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pantothenate kinase YP_002709.1 3399054 R 267671 CDS YP_002710.1 45658624 2770738 complement(3399829..3400593) 1 NC_005823.1 hypothetical protein 3400593 2770738 LIC12793 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002710.1 3399829 R 267671 CDS YP_002711.1 45658625 2770897 complement(3401687..3402214) 1 NC_005823.1 hypothetical protein 3402214 2770897 LIC12794 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002711.1 3401687 R 267671 CDS YP_002712.1 45658626 2771587 complement(3402298..3403623) 1 NC_005823.1 acetyl-CoA acetyltransferase 3403623 2771587 LIC12795 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyl-CoA acetyltransferase YP_002712.1 3402298 R 267671 CDS YP_002713.1 45658627 2770535 complement(3403660..3404520) 1 NC_005823.1 hypothetical protein 3404520 2770535 LIC12796 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002713.1 3403660 R 267671 CDS YP_002714.1 45658628 2770510 3404598..3404798 1 NC_005823.1 hypothetical protein 3404798 2770510 LIC12797 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002714.1 3404598 D 267671 CDS YP_002715.1 45658629 2770203 3404779..3405393 1 NC_005823.1 TetR family transcriptional regulator 3405393 2770203 LIC12798 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 TetR family transcriptional regulator YP_002715.1 3404779 D 267671 CDS YP_002716.1 45658630 2770519 complement(3405758..3406156) 1 NC_005823.1 hypothetical protein 3406156 2770519 LIC12799 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002716.1 3405758 R 267671 CDS YP_002717.1 45658631 2770734 3406421..3406921 1 NC_005823.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 3406921 2770734 LIC12800 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methionine sulfoxide reductase B YP_002717.1 3406421 D 267671 CDS YP_002718.1 45658632 2770085 3407037..3407948 1 NC_005823.1 hypothetical protein 3407948 2770085 LIC12801 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002718.1 3407037 D 267671 CDS YP_002719.1 45658633 2771677 complement(3408674..3409240) 1 NC_005823.1 hypothetical protein 3409240 2771677 LIC12802 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002719.1 3408674 R 267671 CDS YP_002720.1 45658634 2770762 complement(3409237..3409839) 1 NC_005823.1 hypothetical protein 3409839 2770762 LIC12803 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002720.1 3409237 R 267671 CDS YP_002721.1 45658635 2770831 complement(3409809..3410009) 1 NC_005823.1 hypothetical protein 3410009 2770831 LIC12804 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002721.1 3409809 R 267671 CDS YP_002722.1 45658636 2772274 3410105..3411112 1 NC_005823.1 hypothetical protein 3411112 2772274 LIC12805 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002722.1 3410105 D 267671 CDS YP_002723.1 45658637 2770585 3411136..3411558 1 NC_005823.1 hypothetical protein 3411558 2770585 LIC12806 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002723.1 3411136 D 267671 CDS YP_002724.1 45658638 2770810 3412218..3412919 1 NC_005823.1 response regulator 3412919 2770810 LIC12807 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_002724.1 3412218 D 267671 CDS YP_002725.1 45658639 2771961 3412920..3414755 1 NC_005823.1 histidine kinase sensor protein 3414755 2771961 LIC12808 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_002725.1 3412920 D 267671 CDS YP_002726.1 45658640 2770048 complement(3414935..3415180) 1 NC_005823.1 hypothetical protein 3415180 2770048 LIC12809 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002726.1 3414935 R 267671 CDS YP_002727.1 45658641 2771549 complement(3415314..3416231) 1 NC_005823.1 hypothetical protein 3416231 2771549 LIC12810 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002727.1 3415314 R 267671 CDS YP_002728.1 45658642 2770081 complement(3416206..3417231) 1 NC_005823.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 3417231 ruvB 2770081 ruvB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Holliday junction DNA helicase RuvB YP_002728.1 3416206 R 267671 CDS YP_002729.1 45658643 2769918 complement(3417232..3418398) 1 NC_005823.1 serine protease MucD precursor 3418398 mucD 2769918 mucD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 serine protease MucD precursor YP_002729.1 3417232 R 267671 CDS YP_002730.1 45658644 2772667 complement(3418620..3419243) 1 NC_005823.1 serine protease 3419243 2772667 LIC12813 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 serine protease YP_002730.1 3418620 R 267671 CDS YP_002731.1 45658645 2770099 3419353..3419967 1 NC_005823.1 thymidylate kinase 3419967 tmk 2770099 tmk Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thymidylate kinase YP_002731.1 3419353 D 267671 CDS YP_002732.1 45658646 2772923 3420440..3421159 1 NC_005823.1 hypothetical protein 3421159 2772923 LIC12815 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002732.1 3420440 D 267671 CDS YP_002733.1 45658647 2769829 complement(3421306..3421692) 1 NC_005823.1 hypothetical protein 3421692 2769829 LIC12816 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002733.1 3421306 R 267671 CDS YP_002734.1 45658648 2769613 complement(3422352..3422852) 1 NC_005823.1 hypothetical protein 3422852 2769613 LIC12818 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002734.1 3422352 R 267671 CDS YP_002735.1 45658649 2769831 complement(3422871..3423314) 1 NC_005823.1 hypothetical protein 3423314 2769831 LIC12819 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002735.1 3422871 R 267671 CDS YP_002736.1 45658650 2769783 complement(3423358..3424416) 1 NC_005823.1 pyridoxal phosphate biosynthesis protein 3424416 pdxA 2769783 pdxA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pyridoxal phosphate biosynthesis protein YP_002736.1 3423358 R 267671 CDS YP_002737.1 45658651 2772085 complement(3424474..3424914) 1 NC_005823.1 hypothetical protein 3424914 2772085 LIC12821 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002737.1 3424474 R 267671 CDS YP_002738.1 45658652 2770328 complement(3425034..3425801) 1 NC_005823.1 hypothetical protein 3425801 2770328 LIC12822 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002738.1 3425034 R 267671 CDS YP_002739.1 45658653 2772403 complement(3426119..3426301) 1 NC_005823.1 hypothetical protein 3426301 2772403 LIC12823 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002739.1 3426119 R 267671 CDS YP_002740.1 45658654 2772231 complement(3426586..3427281) 1 NC_005823.1 hypothetical protein 3427281 2772231 LIC12824 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002740.1 3426586 R 267671 CDS YP_002741.1 45658655 2770264 complement(3427474..3428019) 1 NC_005823.1 hypothetical protein 3428019 2770264 LIC12825 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002741.1 3427474 R 267671 CDS YP_002742.1 45658656 2772143 3428215..3428748 1 NC_005823.1 hypothetical protein 3428748 2772143 LIC12826 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002742.1 3428215 D 267671 CDS YP_002743.1 45658657 2771488 complement(3429078..3430391) 1 NC_005823.1 hypothetical protein 3430391 2771488 LIC12827 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002743.1 3429078 R 267671 CDS YP_002744.1 45658658 2771895 3430449..3432698 1 NC_005823.1 soluble lytic transglycosylase 3432698 2771895 LIC12828 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 soluble lytic transglycosylase YP_002744.1 3430449 D 267671 CDS YP_002745.1 45658659 2771312 3432810..3434099 1 NC_005823.1 citrate synthase 3434099 gltA 2771312 gltA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 citrate synthase YP_002745.1 3432810 D 267671 CDS YP_002746.1 45658660 2770094 3434138..3435757 1 NC_005823.1 hypothetical protein 3435757 2770094 LIC12830 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002746.1 3434138 D 267671 CDS YP_002747.1 45658661 2771375 3435735..3436682 1 NC_005823.1 SAM dependent methyltransferase 3436682 2771375 LIC12831 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 SAM dependent methyltransferase YP_002747.1 3435735 D 267671 CDS YP_002748.1 45658662 2772018 3436679..3437503 1 NC_005823.1 SpoU family; identified by sequence similarity; ORF located using Blastx/Glimmer; rRNA methylase 3437503 yjfH 2772018 yjfH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 rRNA methylase YP_002748.1 3436679 D 267671 CDS YP_002749.1 45658663 2771490 3437554..3438624 1 NC_005823.1 arabinose kinase 3438624 2771490 LIC12833 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 arabinose kinase YP_002749.1 3437554 D 267671 CDS YP_002750.1 45658664 2772783 complement(3438843..3439886) 1 NC_005823.1 hypothetical protein 3439886 2772783 LIC12834 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002750.1 3438843 R 267671 CDS YP_002751.1 45658665 2771318 complement(3440299..3440817) 1 NC_005823.1 hypothetical protein 3440817 2771318 LIC12835 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002751.1 3440299 R 267671 CDS YP_002752.1 45658666 2771232 3441458..3441778 1 NC_005823.1 hypothetical protein 3441778 2771232 LIC12836 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002752.1 3441458 D 267671 CDS YP_002753.1 45658667 2771563 3441839..3442147 1 NC_005823.1 hypothetical protein 3442147 2771563 LIC12837 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002753.1 3441839 D 267671 CDS YP_002754.1 45658668 2771561 3442504..3443598 1 NC_005823.1 hypothetical protein 3443598 2771561 LIC12838 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002754.1 3442504 D 267671 CDS YP_002755.1 45658669 2772130 3443599..3444561 1 NC_005823.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 3444561 pyrB 2772130 pyrB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aspartate carbamoyltransferase catalytic subunit YP_002755.1 3443599 D 267671 CDS YP_002756.1 45658670 2770417 3444534..3444932 1 NC_005823.1 hypothetical protein 3444932 2770417 LIC12840 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002756.1 3444534 D 267671 CDS YP_002757.1 45658671 2771030 3444916..3446142 1 NC_005823.1 catalyzes the interconversion of tetrahydrodipicolinate and L,L-diaminopimelate in lysine biosynthesis; L,L-diaminopimelate aminotransferase 3446142 ywfG 2771030 ywfG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 L,L-diaminopimelate aminotransferase YP_002757.1 3444916 D 267671 CDS YP_002758.1 45658672 2771004 3448625..3449770 1 NC_005823.1 hypothetical protein 3449770 2771004 LIC12842 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002758.1 3448625 D 267671 CDS YP_002759.1 45658673 2771261 3451125..3451370 1 NC_005823.1 hypothetical protein 3451370 2771261 LIC12843 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002759.1 3451125 D 267671 CDS YP_002760.1 45658674 2770902 3451803..3453722 1 NC_005823.1 hypothetical protein 3453722 2770902 LIC12844 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002760.1 3451803 D 267671 CDS YP_002761.1 45658675 2770645 complement(3455009..3455524) 1 NC_005823.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 3455524 rplQ 2770645 rplQ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L17 YP_002761.1 3455009 R 267671 CDS YP_002762.1 45658676 2771244 complement(3455526..3456503) 1 NC_005823.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 3456503 rpoA 2771244 rpoA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA-directed RNA polymerase subunit alpha YP_002762.1 3455526 R 267671 CDS YP_002763.1 45658677 2772477 complement(3456526..3457149) 1 NC_005823.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3457149 rpsD 2772477 rpsD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S4 YP_002763.1 3456526 R 267671 CDS YP_002764.1 45658678 2770169 complement(3457161..3457571) 1 NC_005823.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 3457571 rpsK 2770169 rpsK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S11 YP_002764.1 3457161 R 267671 CDS YP_002765.1 45658679 2772758 complement(3457574..3457951) 1 NC_005823.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 3457951 rpsM 2772758 rpsM Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S13 YP_002765.1 3457574 R 267671 CDS YP_002766.1 45658680 2771436 complement(3457955..3458068) 1 NC_005823.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 3458068 rpmJ 2771436 rpmJ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L36 YP_002766.1 3457955 R 267671 CDS YP_002767.1 45658681 2772390 complement(3458077..3458295) 1 NC_005823.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 3458295 infA 2772390 infA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 translation initiation factor IF-1 YP_002767.1 3458077 R 267671 CDS YP_002768.1 45658682 2771826 complement(3458298..3458861) 1 NC_005823.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 3458861 adk 2771826 adk Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate kinase YP_002768.1 3458298 R 267671 CDS YP_002769.1 45658683 2771398 complement(3458869..3460251) 1 NC_005823.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 3460251 secY 2771398 secY Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 preprotein translocase subunit SecY YP_002769.1 3458869 R 267671 CDS YP_002770.1 45658684 2770777 complement(3460266..3460808) 1 NC_005823.1 late assembly protein; 50S ribosomal protein L15 3460808 rplO 2770777 rplO Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L15 YP_002770.1 3460266 R 267671 CDS YP_002771.1 45658685 2770909 complement(3460824..3461003) 1 NC_005823.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 3461003 rpmD 2770909 rpmD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L30 YP_002771.1 3460824 R 267671 CDS YP_002772.1 45658686 2770319 complement(3461016..3461522) 1 NC_005823.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 3461522 rpsE 2770319 rpsE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S5 YP_002772.1 3461016 R 267671 CDS YP_002773.1 45658687 2771362 complement(3461524..3461892) 1 NC_005823.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 3461892 rplR 2771362 rplR Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L18 YP_002773.1 3461524 R 267671 CDS YP_002774.1 45658688 2770163 complement(3461896..3462435) 1 NC_005823.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 3462435 rplF 2770163 rplF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L6 YP_002774.1 3461896 R 267671 CDS YP_002775.1 45658689 2772543 complement(3462462..3462863) 1 NC_005823.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 3462863 rpsH 2772543 rpsH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S8 YP_002775.1 3462462 R 267671 CDS YP_002776.1 45658690 2771669 complement(3462883..3463068) 1 NC_005823.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 3463068 rpsN 2771669 rpsN Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S14 YP_002776.1 3462883 R 267671 CDS YP_002777.1 45658691 2771765 complement(3463088..3463636) 1 NC_005823.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 3463636 rplE 2771765 rplE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L5 YP_002777.1 3463088 R 267671 CDS YP_002778.1 45658692 2772430 complement(3463640..3463999) 1 NC_005823.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 3463999 rplX 2772430 rplX Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L24 YP_002778.1 3463640 R 267671 CDS YP_002779.2 161621772 2772819 complement(3463999..3464391) 1 NC_005823.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 3464391 rplN 2772819 rplN Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L14 YP_002779.2 3463999 R 267671 CDS YP_002780.1 45658694 2770296 complement(3464393..3464662) 1 NC_005823.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 3464662 rpsQ 2770296 rpsQ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S17 YP_002780.1 3464393 R 267671 CDS YP_002781.1 45658695 2771243 complement(3464672..3464956) 1 NC_005823.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 3464956 rpmC 2771243 rpmC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L29 YP_002781.1 3464672 R 267671 CDS YP_002782.1 45658696 2772121 complement(3464953..3465366) 1 NC_005823.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 3465366 rplP 2772121 rplP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L16 YP_002782.1 3464953 R 267671 CDS YP_002783.1 45658697 2770356 complement(3465389..3466066) 1 NC_005823.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 3466066 rpsC 2770356 rpsC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S3 YP_002783.1 3465389 R 267671 CDS YP_002784.1 45658698 2769662 complement(3466079..3466411) 1 NC_005823.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 3466411 rplV 2769662 rplV Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L22 YP_002784.1 3466079 R 267671 CDS YP_002785.1 45658699 2770150 complement(3466411..3466692) 1 NC_005823.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 3466692 rpsS 2770150 rpsS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S19 YP_002785.1 3466411 R 267671 CDS YP_002786.1 45658700 2770411 complement(3466701..3467540) 1 NC_005823.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 3467540 rplB 2770411 rplB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L2 YP_002786.1 3466701 R 267671 CDS YP_002787.1 45658701 2771913 complement(3467544..3467858) 1 NC_005823.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 3467858 rplW 2771913 rplW Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L23 YP_002787.1 3467544 R 267671 CDS YP_002788.1 45658702 2770352 complement(3467855..3468490) 1 NC_005823.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 3468490 rplD 2770352 rplD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L4 YP_002788.1 3467855 R 267671 CDS YP_002789.1 45658703 2769472 complement(3468508..3469128) 1 NC_005823.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 3469128 rplC 2769472 rplC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 50S ribosomal protein L3 YP_002789.1 3468508 R 267671 CDS YP_002790.1 45658704 2770684 complement(3469141..3469449) 1 NC_005823.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 3469449 rpsJ 2770684 rpsJ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S10 YP_002790.1 3469141 R 267671 CDS YP_002791.1 45658705 2771672 complement(3469464..3470669) 1 NC_005823.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 3470669 tuf 2771672 tuf Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 elongation factor Tu YP_002791.1 3469464 R 267671 CDS YP_002792.1 45658706 2772061 complement(3470720..3472585) 1 NC_005823.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 3472585 fus 2772061 fus Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 elongation factor G YP_002792.1 3470720 R 267671 CDS YP_002793.1 45658707 2772497 complement(3473251..3474477) 1 NC_005823.1 hypothetical protein 3474477 2772497 LIC12877 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002793.1 3473251 R 267671 CDS YP_002794.1 45658708 2770934 complement(3474482..3475033) 1 NC_005823.1 hypothetical protein 3475033 2770934 LIC12878 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002794.1 3474482 R 267671 CDS YP_002795.1 45658709 2769921 3475407..3475670 1 NC_005823.1 hypothetical protein 3475670 2769921 LIC12879 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002795.1 3475407 D 267671 CDS YP_002796.1 45658710 2771252 complement(3476204..3477070) 1 NC_005823.1 lipoprotein 3477070 2771252 LIC12880 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002796.1 3476204 R 267671 CDS YP_002797.1 45658711 2769851 complement(3477827..3478387) 1 NC_005823.1 hypothetical protein 3478387 2769851 LIC12881 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002797.1 3477827 R 267671 CDS YP_002798.1 45658712 2771469 3479111..3479299 1 NC_005823.1 hypothetical protein 3479299 2771469 LIC12882 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002798.1 3479111 D 267671 CDS YP_002799.1 45658713 2772774 complement(3479445..3482765) 1 NC_005823.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 3482765 carB 2772774 carB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 carbamoyl phosphate synthase large subunit YP_002799.1 3479445 R 267671 CDS YP_002800.1 45658714 2772353 complement(3482892..3484490) 1 NC_005823.1 arylsulfatase 3484490 aslA 2772353 aslA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 arylsulfatase YP_002800.1 3482892 R 267671 CDS YP_002801.1 45658715 2772080 complement(3487108..3487680) 1 NC_005823.1 holliday junction endodeoxyribonuclease protein 3487680 ruvC 2772080 ruvC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 holliday junction endodeoxyribonuclease protein YP_002801.1 3487108 R 267671 CDS YP_002802.1 45658716 2770117 complement(3488641..3489390) 1 NC_005823.1 hypothetical protein 3489390 2770117 LIC12886 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002802.1 3488641 R 267671 CDS YP_002803.1 45658717 2770926 3489577..3490188 1 NC_005823.1 hypothetical protein 3490188 2770926 LIC12887 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002803.1 3489577 D 267671 CDS YP_002804.1 45658718 2771351 complement(3490741..3491295) 1 NC_005823.1 hypothetical protein 3491295 2771351 LIC12888 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002804.1 3490741 R 267671 CDS YP_002805.1 45658719 2772578 complement(3491355..3491678) 1 NC_005823.1 hypothetical protein 3491678 2772578 LIC12889 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002805.1 3491355 R 267671 CDS YP_002806.1 45658720 2772228 3491722..3492231 1 NC_005823.1 hypothetical protein 3492231 2772228 LIC12890 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002806.1 3491722 D 267671 CDS YP_002807.1 45658721 2772269 complement(3492528..3493094) 1 NC_005823.1 lipoprotein 3493094 2772269 LIC12891 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002807.1 3492528 R 267671 CDS YP_002808.1 45658722 2770159 complement(3493390..3494199) 1 NC_005823.1 lipoprotein 3494199 2770159 LIC12892 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002808.1 3493390 R 267671 CDS YP_002809.1 45658723 2772475 complement(3494291..3495052) 1 NC_005823.1 hypothetical protein 3495052 2772475 LIC12893 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002809.1 3494291 R 267671 CDS YP_002810.1 45658724 2769901 complement(3495061..3497235) 1 NC_005823.1 hypothetical protein 3497235 2769901 LIC12894 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002810.1 3495061 R 267671 CDS YP_002811.1 45658725 2772072 complement(3497425..3498099) 1 NC_005823.1 lipoprotein 3498099 2772072 LIC12895 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002811.1 3497425 R 267671 CDS YP_002812.1 45658726 2770857 complement(3498112..3507534) 1 NC_005823.1 internal repeat sequences detected; contains peptidase family M23/M37 as detected by pfam-hmmr; hypothetical protein 3507534 2770857 LIC12896 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002812.1 3498112 R 267671 CDS YP_002813.1 45658727 2770973 3508699..3509613 1 NC_005823.1 hypothetical protein 3509613 2770973 LIC12897 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002813.1 3508699 D 267671 CDS YP_002814.1 45658728 2770805 complement(3509830..3512742) 1 NC_005823.1 hypothetical protein 3512742 2770805 LIC12898 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002814.1 3509830 R 267671 CDS YP_002815.1 45658729 2769933 complement(3513922..3514740) 1 NC_005823.1 contains leucine-rich repeats; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 3514740 2769933 LIC12899 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002815.1 3513922 R 267671 CDS YP_002816.1 45658730 2772467 3514712..3514918 1 NC_005823.1 hypothetical protein 3514918 2772467 LIC12900 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002816.1 3514712 D 267671 CDS YP_002817.1 45658731 2771271 3515383..3520233 1 NC_005823.1 molybdate metabolism regulator 3520233 molR 2771271 molR Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 molybdate metabolism regulator YP_002817.1 3515383 D 267671 CDS YP_002818.1 45658732 2771417 3520640..3521752 1 NC_005823.1 hypothetical protein 3521752 2771417 LIC12902 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002818.1 3520640 D 267671 CDS YP_002819.1 45658733 2771462 3521950..3524247 1 NC_005823.1 hypothetical protein 3524247 2771462 LIC12903 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002819.1 3521950 D 267671 CDS YP_002820.1 45658734 2772564 3524400..3525524 1 NC_005823.1 hypothetical protein 3525524 2772564 LIC12904 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002820.1 3524400 D 267671 CDS YP_002821.1 45658735 2771768 3525532..3527466 1 NC_005823.1 hypothetical protein 3527466 2771768 LIC12905 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002821.1 3525532 D 267671 CDS YP_002822.1 45658736 2772207 complement(3527534..3528256) 1 NC_005823.1 lipoprotein 3528256 2772207 LIC12906 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002822.1 3527534 R 267671 CDS YP_002823.1 45658737 2770579 3528387..3528581 1 NC_005823.1 hypothetical protein 3528581 2770579 LIC12907 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002823.1 3528387 D 267671 CDS YP_002824.1 45658738 2770695 complement(3529726..3531531) 1 NC_005823.1 sodium/glucose cotransport protein 3531531 sglT 2770695 sglT Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sodium/glucose cotransport protein YP_002824.1 3529726 R 267671 CDS YP_002825.1 45658739 2771094 3531712..3532929 1 NC_005823.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 3532929 lysC 2771094 lysC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aspartate kinase YP_002825.1 3531712 D 267671 CDS YP_002826.1 45658740 2771559 3535328..3536461 1 NC_005823.1 hypothetical protein 3536461 2771559 LIC12910 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002826.1 3535328 D 267671 CDS YP_002827.1 45658741 2772419 3536462..3537565 1 NC_005823.1 hypothetical protein 3537565 2772419 LIC12911 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002827.1 3536462 D 267671 CDS YP_002828.1 45658742 2771967 3537565..3538269 1 NC_005823.1 hypothetical protein 3538269 2771967 LIC12912 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002828.1 3537565 D 267671 CDS YP_002829.1 45658743 2772170 3538266..3539981 1 NC_005823.1 hypothetical protein 3539981 2772170 LIC12913 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002829.1 3538266 D 267671 CDS YP_002830.1 45658744 2772523 3539984..3540904 1 NC_005823.1 hypothetical protein 3540904 2772523 LIC12914 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002830.1 3539984 D 267671 CDS YP_002831.1 45658745 2770313 3541044..3541472 1 NC_005823.1 hypothetical protein 3541472 2770313 LIC12915 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002831.1 3541044 D 267671 CDS YP_002832.1 45658746 2772540 3542494..3542766 1 NC_005823.1 hypothetical protein 3542766 2772540 LIC12917 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002832.1 3542494 D 267671 CDS YP_002833.1 45658747 2771823 3542998..3543204 1 NC_005823.1 hypothetical protein 3543204 2771823 LIC12918 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002833.1 3542998 D 267671 CDS YP_002834.1 45658748 2771926 complement(3544098..3544508) 1 NC_005823.1 hypothetical protein 3544508 2771926 LIC12919 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002834.1 3544098 R 267671 CDS YP_002835.1 45658749 2771426 3544609..3544797 1 NC_005823.1 hypothetical protein 3544797 2771426 LIC12920 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002835.1 3544609 D 267671 CDS YP_002836.1 45658750 2769947 3545035..3547113 1 NC_005823.1 methyl-accepting chemotaxis protein 3547113 mcpA 2769947 mcpA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methyl-accepting chemotaxis protein YP_002836.1 3545035 D 267671 CDS YP_002837.1 45658751 2769529 3547209..3548297 1 NC_005823.1 hypothetical protein 3548297 2769529 LIC12922 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002837.1 3547209 D 267671 CDS YP_002838.1 45658752 2770948 3548347..3549891 1 NC_005823.1 hypothetical protein 3549891 2770948 LIC12923 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002838.1 3548347 D 267671 CDS YP_002839.1 45658753 2772911 3552803..3554083 1 NC_005823.1 citrate synthase 3554083 2772911 LIC12925 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 citrate synthase YP_002839.1 3552803 D 267671 CDS YP_002840.1 45658754 2770072 3554139..3554825 1 NC_005823.1 hypothetical protein 3554825 2770072 LIC12926 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002840.1 3554139 D 267671 CDS YP_002841.1 45658755 2771383 complement(3556525..3557547) 1 NC_005823.1 cytochrome c peroxidase 3557547 2771383 LIC12927 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytochrome c peroxidase YP_002841.1 3556525 R 267671 CDS YP_002842.1 45658756 2772727 complement(3557625..3558590) 1 NC_005823.1 beta-lactamase related protein 3558590 2772727 LIC12928 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 beta-lactamase related protein YP_002842.1 3557625 R 267671 CDS YP_002843.1 45658757 2770033 3559253..3559441 1 NC_005823.1 hypothetical protein 3559441 2770033 LIC12929 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002843.1 3559253 D 267671 CDS YP_002844.1 45658758 2770259 complement(3559425..3560750) 1 NC_005823.1 internal repeat sequences detected; hypothetical protein 3560750 2770259 LIC12930 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002844.1 3559425 R 267671 CDS YP_002845.1 45658759 2770320 3562202..3562960 1 NC_005823.1 chemotaxis motility protein A 3562960 2770320 LIC12931 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chemotaxis motility protein A YP_002845.1 3562202 D 267671 CDS YP_002846.1 45658760 2772764 complement(3563707..3564042) 1 NC_005823.1 hypothetical protein 3564042 2772764 LIC12932 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002846.1 3563707 R 267671 CDS YP_002847.1 45658761 2772567 complement(3565060..3565347) 1 NC_005823.1 HNH endonuclease family protein 3565347 2772567 LIC12933 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 HNH endonuclease family protein YP_002847.1 3565060 R 267671 CDS YP_002848.1 45658762 2769787 complement(3565357..3566349) 1 NC_005823.1 mannose-6-phosphate isomerase 3566349 manA 2769787 manA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 mannose-6-phosphate isomerase YP_002848.1 3565357 R 267671 CDS YP_002849.1 45658763 2771938 complement(3566355..3567080) 1 NC_005823.1 DnaJ-like protein 3567080 2771938 LIC12935 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DnaJ-like protein YP_002849.1 3566355 R 267671 CDS YP_002850.1 45658764 2769483 complement(3567090..3567803) 1 NC_005823.1 hypothetical protein 3567803 2769483 LIC12936 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002850.1 3567090 R 267671 CDS YP_002851.1 45658765 2769735 3567911..3568243 1 NC_005823.1 anti-sigma factor antagonist 3568243 2769735 LIC12937 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_002851.1 3567911 D 267671 CDS YP_002852.1 45658766 2769537 3568247..3568762 1 NC_005823.1 hypothetical protein 3568762 2769537 LIC12938 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002852.1 3568247 D 267671 CDS YP_002853.1 45658767 2772487 complement(3568947..3569243) 1 NC_005823.1 hypothetical protein 3569243 2772487 LIC12939 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002853.1 3568947 R 267671 CDS YP_002854.1 45658768 2770624 complement(3569454..3570050) 1 NC_005823.1 contains rhomboid domain; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 3570050 2770624 LIC12940 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002854.1 3569454 R 267671 CDS YP_002855.1 45658769 2772641 complement(3570065..3572065) 1 NC_005823.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 3572065 uvrB 2772641 uvrB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 excinuclease ABC subunit B YP_002855.1 3570065 R 267671 CDS YP_002856.1 45658770 2770827 complement(3572072..3572740) 1 NC_005823.1 hypothetical protein 3572740 2770827 LIC12942 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002856.1 3572072 R 267671 CDS YP_002857.1 45658771 2771918 complement(3572786..3573247) 1 NC_005823.1 tRNA/rRNA methyltransferase 3573247 2771918 LIC12943 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tRNA/rRNA methyltransferase YP_002857.1 3572786 R 267671 CDS YP_002858.1 45658772 2772606 complement(3573252..3574406) 1 NC_005823.1 30S ribosomal protein S1 3574406 2772606 LIC12944 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 30S ribosomal protein S1 YP_002858.1 3573252 R 267671 CDS YP_002859.1 45658773 2772538 3575772..3576539 1 NC_005823.1 hypothetical protein 3576539 2772538 LIC12945 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002859.1 3575772 D 267671 CDS YP_002860.1 45658774 2770345 3576540..3577301 1 NC_005823.1 glycosyl transferase 3577301 2770345 LIC12946 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyl transferase YP_002860.1 3576540 D 267671 CDS YP_002861.1 45658775 2771306 3578456..3579079 1 NC_005823.1 flagellin protein 3579079 2771306 LIC12947 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellin protein YP_002861.1 3578456 D 267671 CDS YP_002862.1 45658776 2770172 complement(3579573..3579974) 1 NC_005823.1 hypothetical protein 3579974 2770172 LIC12948 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002862.1 3579573 R 267671 CDS YP_002863.1 45658777 2772630 3580082..3581023 1 NC_005823.1 shikimate 5-dehydrogenase 3581023 aroE 2772630 aroE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 shikimate 5-dehydrogenase YP_002863.1 3580082 D 267671 CDS YP_002864.1 45658778 2770344 3581020..3582312 1 NC_005823.1 folylpolyglutamate synthase; dihydrofolate synthase 3582312 folC 2770344 folC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dihydrofolate synthase YP_002864.1 3581020 D 267671 CDS YP_002865.1 45658779 2770308 complement(3584661..3586244) 1 NC_005823.1 S-layer-like protein 3586244 2770308 LIC12952 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 S-layer-like protein YP_002865.1 3584661 R 267671 CDS YP_002866.1 45658780 2772198 complement(3586241..3587002) 1 NC_005823.1 dipeptide/oligopeptide ABC transporter permease 3587002 2772198 LIC12953 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dipeptide/oligopeptide ABC transporter permease YP_002866.1 3586241 R 267671 CDS YP_002867.1 45658781 2771567 complement(3586999..3587892) 1 NC_005823.1 oligopeptide ABC transporter permease 3587892 2771567 LIC12954 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 oligopeptide ABC transporter permease YP_002867.1 3586999 R 267671 CDS YP_002868.1 45658782 2772845 complement(3587895..3588362) 1 NC_005823.1 nitrogen regulatory IIA protein 3588362 ptsN 2772845 ptsN Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 nitrogen regulatory IIA protein YP_002868.1 3587895 R 267671 CDS YP_002869.1 45658783 2771789 complement(3588436..3589326) 1 NC_005823.1 hypothetical protein 3589326 2771789 LIC12956 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002869.1 3588436 R 267671 CDS YP_002870.1 45658784 2770803 complement(3589319..3590479) 1 NC_005823.1 hypothetical protein 3590479 2770803 LIC12957 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002870.1 3589319 R 267671 CDS YP_002871.1 45658785 2771254 complement(3590486..3590767) 1 NC_005823.1 hypothetical protein 3590767 2771254 LIC12958 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002871.1 3590486 R 267671 CDS YP_002872.1 45658786 2770071 3591208..3591420 1 NC_005823.1 hypothetical protein 3591420 2770071 LIC12959 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002872.1 3591208 D 267671 CDS YP_002873.1 45658787 2771086 complement(3591745..3593295) 1 NC_005823.1 glycosyltransferase 3593295 2771086 LIC12960 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycosyltransferase YP_002873.1 3591745 R 267671 CDS YP_002874.1 45658788 2770644 complement(3594524..3596419) 1 NC_005823.1 ATP-dependent DNA helicase 3596419 recQ 2770644 recQ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent DNA helicase YP_002874.1 3594524 R 267671 CDS YP_002875.1 45658789 2769973 3598226..3598489 1 NC_005823.1 hypothetical protein 3598489 2769973 LIC12962 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002875.1 3598226 D 267671 CDS YP_002876.1 45658790 2772584 3598814..3600727 1 NC_005823.1 hypothetical protein 3600727 2772584 LIC12963 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002876.1 3598814 D 267671 CDS YP_002877.1 45658791 2770165 complement(3601920..3602906) 1 NC_005823.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 3602906 nadA 2770165 nadA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 quinolinate synthetase YP_002877.1 3601920 R 267671 CDS YP_002878.1 45658792 2772414 complement(3602891..3603460) 1 NC_005823.1 lipoprotein 3603460 2772414 LIC12965 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002878.1 3602891 R 267671 CDS YP_002879.1 45658793 2771916 3603575..3604642 1 NC_005823.1 outer membrane lipoprotein; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 3604642 lipL41 2771916 lipL41 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002879.1 3603575 D 267671 CDS YP_002880.1 45658794 2769998 3604620..3605003 1 NC_005823.1 hypothetical protein 3605003 2769998 LIC12967 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002880.1 3604620 D 267671 CDS YP_002881.1 45658795 2772525 3605596..3605808 1 NC_005823.1 hypothetical protein 3605808 2772525 LIC12968 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002881.1 3605596 D 267671 CDS YP_002882.1 45658796 2771222 complement(3606413..3607615) 1 NC_005823.1 cell division protein; GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 3607615 ftsZ 2771222 ftsZ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cell division protein FtsZ YP_002882.1 3606413 R 267671 CDS YP_002883.1 45658797 2771678 complement(3607634..3608863) 1 NC_005823.1 cell division protein; hypothetical protein 3608863 ftsA 2771678 ftsA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002883.1 3607634 R 267671 CDS YP_002884.1 45658798 2772668 complement(3608865..3609614) 1 NC_005823.1 cell division protein; hypothetical protein 3609614 ftsQ 2772668 ftsQ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002884.1 3608865 R 267671 CDS YP_002885.1 45658799 2770565 3610297..3611097 1 NC_005823.1 hypothetical protein 3611097 2770565 LIC12972 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002885.1 3610297 D 267671 CDS YP_002886.1 45658800 2770311 3611147..3611755 1 NC_005823.1 hypothetical protein 3611755 2770311 LIC12973 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002886.1 3611147 D 267671 CDS YP_002887.1 45658801 2771132 complement(3611773..3612336) 1 NC_005823.1 hypothetical protein 3612336 2771132 LIC12974 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002887.1 3611773 R 267671 CDS YP_002888.1 45658802 2771505 3613159..3613992 1 NC_005823.1 phospholipid synthase 3613992 2771505 LIC12975 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phospholipid synthase YP_002888.1 3613159 D 267671 CDS YP_002889.1 45658803 2770058 complement(3613989..3615245) 1 NC_005823.1 lipoprotein 3615245 2770058 LIC12976 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002889.1 3613989 R 267671 CDS YP_002890.1 45658804 2770651 complement(3615242..3615487) 1 NC_005823.1 hypothetical protein 3615487 2770651 LIC12977 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002890.1 3615242 R 267671 CDS YP_002891.1 45658805 2769991 3615979..3616572 1 NC_005823.1 peptide methionine sulfoxide reductase 2 3616572 msrA 2769991 msrA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peptide methionine sulfoxide reductase 2 YP_002891.1 3615979 D 267671 CDS YP_002892.1 45658806 2772679 complement(3616632..3617357) 1 NC_005823.1 hypothetical protein 3617357 2772679 LIC12979 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002892.1 3616632 R 267671 CDS YP_002893.1 45658807 2770005 3617602..3618057 1 NC_005823.1 hypothetical protein 3618057 2770005 LIC12980 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002893.1 3617602 D 267671 CDS YP_002894.1 45658808 2772053 3618952..3619578 1 NC_005823.1 glutathione S-transferase 3619578 2772053 LIC12981 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutathione S-transferase YP_002894.1 3618952 D 267671 CDS YP_002895.1 45658809 2772684 complement(3620274..3622493) 1 NC_005823.1 heavy-metal transporting p-type ATPase 3622493 2772684 LIC12982 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heavy-metal transporting p-type ATPase YP_002895.1 3620274 R 267671 CDS YP_002896.1 45658810 2769814 complement(3622490..3622690) 1 NC_005823.1 hypothetical protein 3622690 2769814 LIC12983 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002896.1 3622490 R 267671 CDS YP_002897.1 45658811 2770294 complement(3622708..3623001) 1 NC_005823.1 hypothetical protein 3623001 2770294 LIC12984 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002897.1 3622708 R 267671 CDS YP_002898.1 45658812 2769686 complement(3623374..3624315) 1 NC_005823.1 hypothetical protein 3624315 2769686 LIC12985 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002898.1 3623374 R 267671 CDS YP_002899.1 45658813 2771951 complement(3624980..3626878) 1 NC_005823.1 hypothetical protein 3626878 2771951 LIC12986 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002899.1 3624980 R 267671 CDS YP_002900.1 45658814 2772313 complement(3627060..3627314) 1 NC_005823.1 hypothetical protein 3627314 2772313 LIC12987 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002900.1 3627060 R 267671 CDS YP_002901.1 45658815 2770011 3628817..3629737 1 NC_005823.1 lipase 3629737 2770011 LIC12988 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipase YP_002901.1 3628817 D 267671 CDS YP_002902.1 45658816 2772291 complement(3630851..3633952) 1 NC_005823.1 heavy metal efflux pump 3633952 helA 2772291 helA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heavy metal efflux pump YP_002902.1 3630851 R 267671 CDS YP_002903.1 45658817 2772588 complement(3633933..3635312) 1 NC_005823.1 hypothetical protein 3635312 2772588 LIC12990 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002903.1 3633933 R 267671 CDS YP_002904.1 45658818 2769490 complement(3635436..3635813) 1 NC_005823.1 hypothetical protein 3635813 2769490 LIC12991 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002904.1 3635436 R 267671 CDS YP_002905.1 45658819 2769644 complement(3636410..3638662) 1 NC_005823.1 sulfate permease 3638662 sulP 2769644 sulP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sulfate permease YP_002905.1 3636410 R 267671 CDS YP_002906.1 45658820 2769573 complement(3638677..3639126) 1 NC_005823.1 hypothetical protein 3639126 2769573 LIC12993 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002906.1 3638677 R 267671 CDS YP_002907.1 45658821 2769721 3639848..3640987 1 NC_005823.1 hypothetical protein 3640987 2769721 LIC12994 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002907.1 3639848 D 267671 CDS YP_002908.1 45658822 2771493 complement(3641262..3642269) 1 NC_005823.1 hypothetical protein 3642269 2771493 LIC12995 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002908.1 3641262 R 267671 CDS YP_002909.1 45658823 2770484 complement(3642311..3642955) 1 NC_005823.1 dedA family; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 3642955 2770484 LIC12996 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002909.1 3642311 R 267671 CDS YP_002910.1 45658824 2770343 complement(3643208..3643561) 1 NC_005823.1 hypothetical protein 3643561 2770343 LIC12997 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002910.1 3643208 R 267671 CDS YP_002911.1 45658825 2772767 complement(3643668..3646193) 1 NC_005823.1 TonB-dependent outer membrane receptor 3646193 2772767 LIC12998 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 TonB-dependent outer membrane receptor YP_002911.1 3643668 R 267671 CDS YP_002912.1 45658826 2770209 complement(3646206..3647414) 1 NC_005823.1 hypothetical protein 3647414 2770209 LIC12999 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002912.1 3646206 R 267671 CDS YP_002913.1 45658827 2770240 complement(3647411..3648292) 1 NC_005823.1 hypothetical protein 3648292 2770240 LIC13000 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002913.1 3647411 R 267671 CDS YP_002914.1 45658828 2769730 complement(3648329..3650545) 1 NC_005823.1 hypothetical protein 3650545 2769730 LIC13001 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002914.1 3648329 R 267671 CDS YP_002915.1 45658829 2769830 3650826..3652247 1 NC_005823.1 hypothetical protein 3652247 2769830 LIC13002 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002915.1 3650826 D 267671 CDS YP_002916.1 45658830 2770177 complement(3653236..3654825) 1 NC_005823.1 short-chain dehydrogenase 3654825 2770177 LIC13003 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 short-chain dehydrogenase YP_002916.1 3653236 R 267671 CDS YP_002917.1 45658831 2769712 3655614..3656858 1 NC_005823.1 adenylate/guanylate cyclase 3656858 2769712 LIC13004 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_002917.1 3655614 D 267671 CDS YP_002918.1 45658832 2769821 complement(3657241..3657747) 1 NC_005823.1 hypothetical protein 3657747 2769821 LIC13005 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002918.1 3657241 R 267671 CDS YP_002919.1 45658833 2769785 3658035..3659423 1 NC_005823.1 lipoprotein 3659423 2769785 LIC13006 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002919.1 3658035 D 267671 CDS YP_002920.1 45658834 2771781 complement(3659609..3660091) 1 NC_005823.1 hypothetical protein 3660091 2771781 LIC13007 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002920.1 3659609 R 267671 CDS YP_002921.1 45658835 2769681 complement(3660678..3661076) 1 NC_005823.1 hypothetical protein 3661076 2769681 LIC13008 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002921.1 3660678 R 267671 CDS YP_002922.1 45658836 2769732 complement(3661220..3662893) 1 NC_005823.1 acyl-CoA dehydrogenase 3662893 2769732 LIC13009 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyl-CoA dehydrogenase YP_002922.1 3661220 R 267671 CDS YP_002923.1 45658837 2769738 3663228..3664301 1 NC_005823.1 ankyrin 3664301 2769738 LIC13010 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ankyrin YP_002923.1 3663228 D 267671 CDS YP_002924.1 45658838 2769688 complement(3664522..3665274) 1 NC_005823.1 lipoprotein 3665274 2769688 LIC13011 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002924.1 3664522 R 267671 CDS YP_002925.1 45658839 2769952 3665759..3668782 1 NC_005823.1 hypothetical protein 3668782 2769952 LIC13012 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002925.1 3665759 D 267671 CDS YP_002926.1 45658840 2770964 complement(3668834..3669022) 1 NC_005823.1 hypothetical protein 3669022 2770964 LIC13013 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002926.1 3668834 R 267671 CDS YP_002927.1 45658841 2771833 complement(3669253..3669510) 1 NC_005823.1 hypothetical protein 3669510 2771833 LIC13014 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002927.1 3669253 R 267671 CDS YP_002928.1 45658842 2770609 complement(3670684..3671724) 1 NC_005823.1 hypothetical protein 3671724 2770609 LIC13015 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002928.1 3670684 R 267671 CDS YP_002929.1 45658843 2770807 complement(3671749..3672312) 1 NC_005823.1 phosphoribosyl-AMP cyclohydrolase protein 3672312 hisI 2770807 hisI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoribosyl-AMP cyclohydrolase protein YP_002929.1 3671749 R 267671 CDS YP_002930.1 45658844 2772747 complement(3673377..3676688) 1 NC_005823.1 acriflavine resistance 3676688 2772747 LIC13017 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acriflavine resistance YP_002930.1 3673377 R 267671 CDS YP_002931.1 45658845 2769930 complement(3678352..3678879) 1 NC_005823.1 hypothetical protein 3678879 2769930 LIC13018 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002931.1 3678352 R 267671 CDS YP_002932.1 45658846 2769899 complement(3678879..3679343) 1 NC_005823.1 hypothetical protein 3679343 2769899 LIC13019 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002932.1 3678879 R 267671 CDS YP_002933.2 304570503 2771631 3679503..3680189 1 NC_005823.1 hypothetical protein 3680189 2771631 LIC13020 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002933.2 3679503 D 267671 CDS YP_002934.1 45658848 2772216 complement(3680746..3683319) 1 NC_005823.1 hypothetical protein 3683319 2772216 LIC13021 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002934.1 3680746 R 267671 CDS YP_002935.1 45658849 2770310 3683396..3684571 1 NC_005823.1 hypothetical protein 3684571 2770310 LIC13022 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002935.1 3683396 D 267671 CDS YP_002936.1 45658850 2771307 3685040..3686362 1 NC_005823.1 hypothetical protein 3686362 2771307 LIC13023 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002936.1 3685040 D 267671 CDS YP_002937.1 45658851 2772546 3686669..3687037 1 NC_005823.1 hypothetical protein 3687037 2772546 LIC13024 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002937.1 3686669 D 267671 CDS YP_002938.1 45658852 2771329 3687142..3687573 1 NC_005823.1 hypothetical protein 3687573 2771329 LIC13025 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002938.1 3687142 D 267671 CDS YP_002939.1 45658853 2770559 complement(3688698..3689402) 1 NC_005823.1 ThiJ/PfpI family protein 3689402 2770559 LIC13026 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ThiJ/PfpI family protein YP_002939.1 3688698 R 267671 CDS YP_002940.1 45658854 2770720 3689502..3690191 1 NC_005823.1 hypothetical protein 3690191 2770720 LIC13027 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002940.1 3689502 D 267671 CDS YP_002941.1 45658855 2769903 complement(3690802..3691821) 1 NC_005823.1 hypothetical protein 3691821 2769903 LIC13028 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002941.1 3690802 R 267671 CDS YP_002942.1 45658856 2772824 3691869..3692822 1 NC_005823.1 hypothetical protein 3692822 2772824 LIC13029 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002942.1 3691869 D 267671 CDS YP_002943.1 45658857 2772655 complement(3693380..3693970) 1 NC_005823.1 hypothetical protein 3693970 2772655 LIC13030 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002943.1 3693380 R 267671 CDS YP_002944.1 45658858 2771761 complement(3695236..3696345) 1 NC_005823.1 aminotransferase 3696345 2771761 LIC13031 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aminotransferase YP_002944.1 3695236 R 267671 CDS YP_002945.1 45658859 2770869 complement(3697262..3698161) 1 NC_005823.1 hypothetical protein 3698161 2770869 LIC13032 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002945.1 3697262 R 267671 CDS YP_002946.1 45658860 2772438 3699894..3701174 1 NC_005823.1 chitinase 3701174 cht 2772438 cht Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chitinase YP_002946.1 3699894 D 267671 CDS YP_002947.1 45658861 2772459 3702104..3702346 1 NC_005823.1 hypothetical protein 3702346 2772459 LIC13034 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002947.1 3702104 D 267671 CDS YP_002948.1 45658862 2770346 complement(3707737..3708120) 1 NC_005823.1 lipoprotein 3708120 2770346 LIC13036 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002948.1 3707737 R 267671 CDS YP_002949.1 45658863 2769945 complement(3708144..3709625) 1 NC_005823.1 amino acid transporter 3709625 2769945 LIC13037 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 amino acid transporter YP_002949.1 3708144 R 267671 CDS YP_002950.1 45658864 2771674 complement(3710444..3711577) 1 NC_005823.1 hypothetical protein 3711577 2771674 LIC13038 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002950.1 3710444 R 267671 CDS YP_002951.1 45658865 2772006 3711765..3712214 1 NC_005823.1 MarR family transcriptional regulator 3712214 2772006 LIC13039 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 MarR family transcriptional regulator YP_002951.1 3711765 D 267671 CDS YP_002952.1 45658866 2772416 3712279..3712551 1 NC_005823.1 hypothetical protein 3712551 2772416 LIC13040 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002952.1 3712279 D 267671 CDS YP_002953.1 45658867 2771396 3712638..3713081 1 NC_005823.1 hypothetical protein 3713081 2771396 LIC13041 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002953.1 3712638 D 267671 CDS YP_002954.1 45658868 2770333 3713784..3714062 1 NC_005823.1 hypothetical protein 3714062 2770333 LIC13042 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002954.1 3713784 D 267671 CDS YP_002955.1 45658869 2770043 3714059..3714394 1 NC_005823.1 hypothetical protein 3714394 2770043 LIC13043 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002955.1 3714059 D 267671 CDS YP_002956.1 45658870 2772111 complement(3714629..3715867) 1 NC_005823.1 hypothetical protein 3715867 2772111 LIC13044 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002956.1 3714629 R 267671 CDS YP_002957.1 45658871 2772043 complement(3716132..3717022) 1 NC_005823.1 hypothetical protein 3717022 2772043 LIC13045 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002957.1 3716132 R 267671 CDS YP_002958.1 45658872 2770823 complement(3717927..3718949) 1 NC_005823.1 UDP glucosamine N-acyltransferase 3718949 2770823 LIC13046 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP glucosamine N-acyltransferase YP_002958.1 3717927 R 267671 CDS YP_002959.1 45658873 2771480 complement(3719569..3719865) 1 NC_005823.1 hypothetical protein 3719865 2771480 LIC13047 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002959.1 3719569 R 267671 CDS YP_002960.1 45658874 2771162 complement(3721189..3721371) 1 NC_005823.1 hypothetical protein 3721371 2771162 LIC13048 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002960.1 3721189 R 267671 CDS YP_002961.1 45658875 2770412 complement(3721704..3722381) 1 NC_005823.1 hypothetical protein 3722381 2770412 LIC13049 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002961.1 3721704 R 267671 CDS YP_002962.1 45658876 2772226 3722466..3723566 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 3723566 2772226 LIC13050 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002962.1 3722466 D 267671 CDS YP_002963.1 45658877 2770031 3723659..3724414 1 NC_005823.1 late competence protein; ComFC-like protein 3724414 2770031 LIC13051 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ComFC-like protein YP_002963.1 3723659 D 267671 CDS YP_002964.1 45658878 2772261 3724436..3725530 1 NC_005823.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 3725530 dinP 2772261 dinP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA polymerase IV YP_002964.1 3724436 D 267671 CDS YP_002965.1 45658879 2772063 complement(3726617..3727714) 1 NC_005823.1 fatty acid desaturase 3727714 desA 2772063 desA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 fatty acid desaturase YP_002965.1 3726617 R 267671 CDS YP_002966.1 45658880 2769986 3728126..3728344 1 NC_005823.1 hypothetical protein 3728344 2769986 LIC13054 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002966.1 3728126 D 267671 CDS YP_002967.1 45658881 2772181 complement(3728504..3729181) 1 NC_005823.1 hypothetical protein 3729181 2772181 LIC13055 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002967.1 3728504 R 267671 CDS YP_002968.1 45658882 2772539 3729312..3729983 1 NC_005823.1 flagellar motor protein 3729983 2772539 LIC13056 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar motor protein YP_002968.1 3729312 D 267671 CDS YP_002969.1 45658883 2769979 complement(3730663..3731019) 1 NC_005823.1 hypothetical protein 3731019 2769979 LIC13057 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002969.1 3730663 R 267671 CDS YP_002970.1 45658884 2772672 complement(3731549..3731941) 1 NC_005823.1 hypothetical protein 3731941 2772672 LIC13058 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002970.1 3731549 R 267671 CDS YP_002971.1 45658885 2769935 3733568..3734263 1 NC_005823.1 lipoprotein 3734263 2769935 LIC13059 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002971.1 3733568 D 267671 CDS YP_002972.1 45658886 2770515 complement(3735587..3736687) 1 NC_005823.1 outer membrance liopprotein; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 3736687 lipL36 2770515 lipL36 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002972.1 3735587 R 267671 CDS YP_002973.1 45658887 2770922 3738039..3738347 1 NC_005823.1 transposase, ISlin1 3738347 2770922 LIC13061 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_002973.1 3738039 D 267671 CDS YP_002974.1 45658888 2772146 3738385..3738990 1 NC_005823.1 transposase, ISlin1 3738990 2772146 LIC13062 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_002974.1 3738385 D 267671 CDS YP_002975.1 45658889 2771237 3738996..3739355 1 NC_005823.1 transposase, ISlin1 3739355 2771237 LIC13063 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_002975.1 3738996 D 267671 CDS YP_002976.1 45658890 2771830 complement(3739853..3740446) 1 NC_005823.1 3-methyl-adenine DNA glycosylase I 3740446 tag 2771830 tag Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-methyl-adenine DNA glycosylase I YP_002976.1 3739853 R 267671 CDS YP_002977.1 45658891 2770495 complement(3741021..3742034) 1 NC_005823.1 hypothetical protein 3742034 2770495 LIC13065 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002977.1 3741021 R 267671 CDS YP_002978.1 45658892 2771591 3742428..3743855 1 NC_005823.1 lipoprotein 3743855 2771591 LIC13066 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002978.1 3742428 D 267671 CDS YP_002979.1 45658893 2770707 complement(3744253..3744612) 1 NC_005823.1 transposase, ISlin1 3744612 2770707 LIC13067 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_002979.1 3744253 R 267671 CDS YP_002980.1 45658894 2770517 complement(3744618..3745223) 1 NC_005823.1 transposase, ISlin1 3745223 2770517 LIC13068 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_002980.1 3744618 R 267671 CDS YP_002981.1 45658895 2771717 complement(3745261..3745533) 1 NC_005823.1 transposase, ISlin1 3745533 2771717 LIC13069 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_002981.1 3745261 R 267671 CDS YP_002982.1 45658896 2771737 complement(3746896..3748236) 1 NC_005823.1 hypothetical protein 3748236 2771737 LIC13070 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002982.1 3746896 R 267671 CDS YP_002983.1 45658897 2771115 complement(3749072..3749617) 1 NC_005823.1 hypothetical protein 3749617 2771115 LIC13071 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002983.1 3749072 R 267671 CDS YP_002984.1 45658898 2771806 3751557..3753464 1 NC_005823.1 adenylate/guanylate cyclase 3753464 2771806 LIC13072 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_002984.1 3751557 D 267671 CDS YP_002985.1 45658899 2771927 complement(3754017..3754646) 1 NC_005823.1 TetR family transcriptional regulator 3754646 2771927 LIC13073 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 TetR family transcriptional regulator YP_002985.1 3754017 R 267671 CDS YP_002986.1 45658900 2772305 complement(3754753..3758004) 1 NC_005823.1 acriflavin resistance 3758004 2772305 LIC13074 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acriflavin resistance YP_002986.1 3754753 R 267671 CDS YP_002987.1 45658901 2771853 complement(3759682..3760398) 1 NC_005823.1 lipoprotein 3760398 2771853 LIC13075 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002987.1 3759682 R 267671 CDS YP_002988.1 45658902 2770263 complement(3760408..3761142) 1 NC_005823.1 lipoprotein 3761142 2770263 LIC13076 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002988.1 3760408 R 267671 CDS YP_002989.1 45658903 2770942 3761565..3762572 1 NC_005823.1 hypothetical protein 3762572 2770942 LIC13077 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002989.1 3761565 D 267671 CDS YP_002990.1 45658904 2771891 3762760..3763629 1 NC_005823.1 hypothetical protein 3763629 2771891 LIC13078 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002990.1 3762760 D 267671 CDS YP_002991.1 45658905 2772026 complement(3764569..3764988) 1 NC_005823.1 hypothetical protein 3764988 2772026 LIC13079 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002991.1 3764569 R 267671 CDS YP_002992.1 45658906 2772359 complement(3765061..3765930) 1 NC_005823.1 pirin 3765930 2772359 LIC13080 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pirin YP_002992.1 3765061 R 267671 CDS YP_002993.1 45658907 2771880 3766017..3766490 1 NC_005823.1 hypothetical protein 3766490 2771880 LIC13081 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002993.1 3766017 D 267671 CDS YP_002994.1 45658908 2772068 3766557..3768233 1 NC_005823.1 histidine kinase response regulator hybrid protein 3768233 2772068 LIC13082 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase response regulator hybrid protein YP_002994.1 3766557 D 267671 CDS YP_002995.1 45658909 2772140 complement(3768919..3769566) 1 NC_005823.1 hypothetical protein 3769566 2772140 LIC13083 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002995.1 3768919 R 267671 CDS YP_002996.1 45658910 2770980 complement(3769620..3770363) 1 NC_005823.1 hypothetical protein 3770363 2770980 LIC13084 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_002996.1 3769620 R 267671 CDS YP_002997.1 45658911 2771832 complement(3770360..3770950) 1 NC_005823.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 3770950 coaE 2771832 coaE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dephospho-CoA kinase YP_002997.1 3770360 R 267671 CDS YP_002998.1 45658912 2771602 3772523..3773833 1 NC_005823.1 lipoprotein 3773833 2771602 LIC13086 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_002998.1 3772523 D 267671 CDS YP_002999.1 45658913 2771474 3773916..3774977 1 NC_005823.1 histidine kinase sensor protein 3774977 2771474 LIC13087 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_002999.1 3773916 D 267671 CDS YP_003000.1 45658914 2771628 3774974..3775645 1 NC_005823.1 response regulator 3775645 2771628 LIC13088 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_003000.1 3774974 D 267671 CDS YP_003001.1 45658915 2772038 3776571..3778235 1 NC_005823.1 hypothetical protein 3778235 2772038 LIC13089 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003001.1 3776571 D 267671 CDS YP_003002.1 45658916 2772720 complement(3778842..3781994) 1 NC_005823.1 acriflavin resistance 3781994 2772720 LIC13090 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acriflavin resistance YP_003002.1 3778842 R 267671 CDS YP_003003.1 45658917 2772626 complement(3782527..3782724) 1 NC_005823.1 hypothetical protein 3782724 2772626 LIC13091 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003003.1 3782527 R 267671 CDS YP_003004.2 304570504 2770066 3782690..3783562 1 NC_005823.1 peptidase; protease IV; PfaP 3783562 pfaP 2770066 pfaP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 PfaP YP_003004.2 3782690 D 267671 CDS YP_003005.1 45658919 2771603 3783569..3784168 1 NC_005823.1 hypothetical protein 3784168 2771603 LIC13093 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003005.1 3783569 D 267671 CDS YP_003006.1 45658920 2772527 3784165..3784917 1 NC_005823.1 survival protein 3784917 surE 2772527 surE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 survival protein YP_003006.1 3784165 D 267671 CDS YP_003007.1 45658921 2770006 3785858..3786565 1 NC_005823.1 internal repeat sequences detected; contains TPR domain as detected by pfam-hmmr; hypothetical protein 3786565 2770006 LIC13095 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003007.1 3785858 D 267671 CDS YP_003008.1 45658922 2769609 complement(3787335..3787955) 1 NC_005823.1 hypothetical protein 3787955 2769609 LIC13099 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003008.1 3787335 R 267671 CDS YP_003009.1 45658923 2769708 3788026..3788940 1 NC_005823.1 sugar nucleotide epimerase 3788940 2769708 LIC13100 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sugar nucleotide epimerase YP_003009.1 3788026 D 267671 CDS YP_003010.1 45658924 2769572 complement(3789417..3793196) 1 NC_005823.1 alpha integrin 3793196 2769572 LIC13101 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alpha integrin YP_003010.1 3789417 R 267671 CDS YP_003011.1 45658925 2769711 complement(3794701..3795318) 1 NC_005823.1 uracil DNA glycosylase 3795318 2769711 LIC13102 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 uracil DNA glycosylase YP_003011.1 3794701 R 267671 CDS YP_003012.1 45658926 2769673 complement(3795332..3795775) 1 NC_005823.1 anti-sigma factor antagonist 3795775 2769673 LIC13103 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_003012.1 3795332 R 267671 CDS YP_003013.1 45658927 2769690 complement(3795772..3796926) 1 NC_005823.1 galactokinase 3796926 galK 2769690 galK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 galactokinase YP_003013.1 3795772 R 267671 CDS YP_003014.1 45658928 2771728 3798330..3799667 1 NC_005823.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 3799667 pgi 2771728 pgi Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glucose-6-phosphate isomerase YP_003014.1 3798330 D 267671 CDS YP_003015.1 45658929 2771915 3799814..3800134 1 NC_005823.1 hypothetical protein 3800134 2771915 LIC13106 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003015.1 3799814 D 267671 CDS YP_003016.1 45658930 2769699 3801209..3802087 1 NC_005823.1 hypothetical protein 3802087 2769699 LIC13107 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003016.1 3801209 D 267671 CDS YP_003017.1 45658931 2770059 complement(3802503..3803231) 1 NC_005823.1 sugar-phosphate nucleotidyl transferase 3803231 2770059 LIC13108 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sugar-phosphate nucleotidyl transferase YP_003017.1 3802503 R 267671 CDS YP_003018.1 45658932 2772750 complement(3803228..3804223) 1 NC_005823.1 hypothetical protein 3804223 2772750 LIC13109 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003018.1 3803228 R 267671 CDS YP_003019.1 45658933 2771213 complement(3804228..3805751) 1 NC_005823.1 histidine kinase response regulator hybrid protein 3805751 2771213 LIC13110 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase response regulator hybrid protein YP_003019.1 3804228 R 267671 CDS YP_003020.1 45658934 2769626 complement(3805797..3808106) 1 NC_005823.1 histidine kinase sensor protein 3808106 2769626 LIC13111 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_003020.1 3805797 R 267671 CDS YP_003021.1 45658935 2771973 complement(3808142..3808345) 1 NC_005823.1 hypothetical protein 3808345 2771973 LIC13112 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003021.1 3808142 R 267671 CDS YP_003022.1 45658936 2770431 3808942..3809847 1 NC_005823.1 alpha/beta hydrolase superfamily; identified by sequence similarity; ORF located using Blastx/Glimmer; acyltransferase 3809847 2770431 LIC13113 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyltransferase YP_003022.1 3808942 D 267671 CDS YP_003023.1 45658937 2769914 complement(3810555..3810902) 1 NC_005823.1 transposase, ISlin1 3810902 2769914 LIC13114 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_003023.1 3810555 R 267671 CDS YP_003024.1 45658938 2771790 complement(3810912..3811517) 1 NC_005823.1 transposase, ISlin1 3811517 2771790 LIC13115 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_003024.1 3810912 R 267671 CDS YP_003025.1 45658939 2772252 complement(3811555..3811893) 1 NC_005823.1 transposase, ISlin1 3811893 2772252 LIC13116 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_003025.1 3811555 R 267671 CDS YP_003026.1 45658940 2771740 complement(3812885..3813751) 1 NC_005823.1 metallo-beta-lactamase 3813751 2771740 LIC13117 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 metallo-beta-lactamase YP_003026.1 3812885 R 267671 CDS YP_003027.1 45658941 2770317 3814758..3815966 1 NC_005823.1 amino-sugar biosynthesis protein 3815966 wlbF 2770317 wlbF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 amino-sugar biosynthesis protein YP_003027.1 3814758 D 267671 CDS YP_003028.1 45658942 2772275 complement(3817224..3817625) 1 NC_005823.1 hypothetical protein 3817625 2772275 LIC13119 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003028.1 3817224 R 267671 CDS YP_003029.1 45658943 2770968 3818128..3819795 1 NC_005823.1 contains EAL domain; identified by sequence similarity; ORF located using Blastx/Glimmer; diguanylate phosphodiesterase 3819795 2770968 LIC13120 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 diguanylate phosphodiesterase YP_003029.1 3818128 D 267671 CDS YP_003030.1 45658944 2771258 complement(3820390..3821262) 1 NC_005823.1 hypothetical protein 3821262 2771258 LIC13121 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003030.1 3820390 R 267671 CDS YP_003031.1 45658945 2772294 3821306..3821899 1 NC_005823.1 hypothetical protein 3821899 2772294 LIC13122 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003031.1 3821306 D 267671 CDS YP_003032.1 45658946 2770992 3821950..3822825 1 NC_005823.1 hypothetical protein 3822825 2770992 LIC13123 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003032.1 3821950 D 267671 CDS YP_003033.1 45658947 2772833 complement(3823468..3824034) 1 NC_005823.1 hypothetical protein 3824034 2772833 LIC13125 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003033.1 3823468 R 267671 CDS YP_003034.1 45658948 2771976 3825437..3826597 1 NC_005823.1 AraC family transcriptional regulator 3826597 2771976 LIC13126 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 AraC family transcriptional regulator YP_003034.1 3825437 D 267671 CDS YP_003035.1 45658949 2772553 complement(3828113..3829138) 1 NC_005823.1 hypothetical protein 3829138 2772553 LIC13127 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003035.1 3828113 R 267671 CDS YP_003036.1 45658950 2770531 complement(3829213..3829764) 1 NC_005823.1 hypothetical protein 3829764 2770531 LIC13128 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003036.1 3829213 R 267671 CDS YP_003037.1 45658951 2772511 3829833..3831980 1 NC_005823.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 3831980 metG 2772511 metG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methionyl-tRNA synthetase YP_003037.1 3829833 D 267671 CDS YP_003038.1 45658952 2770288 3832946..3835576 1 NC_005823.1 protein-PII uridylyltransferase 3835576 glnD 2770288 glnD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 protein-PII uridylyltransferase YP_003038.1 3832946 D 267671 CDS YP_003039.1 45658953 2770556 complement(3835620..3836165) 1 NC_005823.1 hypothetical protein 3836165 2770556 LIC13131 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003039.1 3835620 R 267671 CDS YP_003040.1 45658954 2772164 complement(3836181..3836915) 1 NC_005823.1 hypothetical protein 3836915 2772164 LIC13132 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003040.1 3836181 R 267671 CDS YP_003041.1 45658955 2770601 complement(3837388..3838353) 1 NC_005823.1 NAD(P)H steroid dehydrogenase 3838353 nsdHL 2770601 nsdHL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NAD(P)H steroid dehydrogenase YP_003041.1 3837388 R 267671 CDS YP_003042.1 45658956 2770617 3839317..3842484 1 NC_005823.1 acriflavin resistance 3842484 acrD 2770617 acrD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acriflavin resistance YP_003042.1 3839317 D 267671 CDS YP_003043.1 45658957 2772671 3843112..3845142 1 NC_005823.1 outer membrane protein 3845142 tolC 2772671 tolC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 outer membrane protein YP_003043.1 3843112 D 267671 CDS YP_003044.1 45658958 2771696 3845185..3846972 1 NC_005823.1 acyl-CoA dehydrogenase 3846972 acd 2771696 acd Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyl-CoA dehydrogenase YP_003044.1 3845185 D 267671 CDS YP_003045.1 45658959 2770816 3847833..3848816 1 NC_005823.1 cGMP-specific phosphodiesterase 3848816 2770816 LIC13137 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cGMP-specific phosphodiesterase YP_003045.1 3847833 D 267671 CDS YP_003046.1 45658960 2772682 complement(3849035..3850027) 1 NC_005823.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 3850027 murB 2772682 murB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-N-acetylenolpyruvoylglucosamine reductase YP_003046.1 3849035 R 267671 CDS YP_003047.1 45658961 2770366 complement(3850719..3850919) 1 NC_005823.1 hypothetical protein 3850919 2770366 LIC13139 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003047.1 3850719 R 267671 CDS YP_003048.1 45658962 2771856 3851000..3851257 1 NC_005823.1 hypothetical protein 3851257 2771856 LIC13140 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003048.1 3851000 D 267671 CDS YP_003049.1 45658963 2771363 complement(3851393..3852079) 1 NC_005823.1 panthotenate metabolism flavoprotein 3852079 dfp 2771363 dfp Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 panthotenate metabolism flavoprotein YP_003049.1 3851393 R 267671 CDS YP_003050.1 45658964 2770341 complement(3852096..3852638) 1 NC_005823.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 3852638 2770341 LIC13142 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphopantothenoylcysteine decarboxylase YP_003050.1 3852096 R 267671 CDS YP_003051.1 45658965 2771573 complement(3852654..3853988) 1 NC_005823.1 contains CBS domains; identified by sequence similarity; ORF located using Blastx/Glimmer; hemolysin 3853988 tlyC 2771573 tlyC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hemolysin YP_003051.1 3852654 R 267671 CDS YP_003052.1 45658966 2770321 complement(3854208..3856793) 1 NC_005823.1 hypothetical protein 3856793 2770321 LIC13144 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003052.1 3854208 R 267671 CDS YP_003053.1 45658967 2770144 complement(3856799..3857806) 1 NC_005823.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 3857806 gpsA 2770144 gpsA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_003053.1 3856799 R 267671 CDS YP_003054.1 45658968 2772921 3857935..3858621 1 NC_005823.1 hypothetical protein 3858621 2772921 LIC13146 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003054.1 3857935 D 267671 CDS YP_003055.1 45658969 2769694 3858733..3859734 1 NC_005823.1 hypothetical protein 3859734 2769694 LIC13147 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003055.1 3858733 D 267671 CDS YP_003056.1 45658970 2770190 3859737..3860414 1 NC_005823.1 hypothetical protein 3860414 2770190 LIC13148 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003056.1 3859737 D 267671 CDS YP_003057.1 45658971 2769611 3860411..3860830 1 NC_005823.1 hypothetical protein 3860830 2769611 LIC13149 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003057.1 3860411 D 267671 CDS YP_003058.1 45658972 2769608 3860811..3862985 1 NC_005823.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 3862985 2769608 LIC13150 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent DNA helicase RecG YP_003058.1 3860811 D 267671 CDS YP_003059.1 45658973 2769825 complement(3864461..3864808) 1 NC_005823.1 lipoprotein 3864808 2769825 LIC13151 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003059.1 3864461 R 267671 CDS YP_003060.1 45658974 2769808 3865009..3865743 1 NC_005823.1 D-alanyl-D-alanine carboxypeptidase 3865743 dac 2769808 dac Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 D-alanyl-D-alanine carboxypeptidase YP_003060.1 3865009 D 267671 CDS YP_003061.1 45658975 2770931 complement(3865744..3866715) 1 NC_005823.1 UDP-glucose 4-epimerase 3866715 2770931 LIC13153 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-glucose 4-epimerase YP_003061.1 3865744 R 267671 CDS YP_003062.1 45658976 2772266 complement(3866712..3867491) 1 NC_005823.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 3867491 lpxA 2772266 lpxA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-N-acetylglucosamine acyltransferase YP_003062.1 3866712 R 267671 CDS YP_003063.1 45658977 2770522 3867637..3867984 1 NC_005823.1 hypothetical protein 3867984 2770522 LIC13155 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003063.1 3867637 D 267671 CDS YP_003064.1 45658978 2771667 complement(3868165..3868362) 1 NC_005823.1 hypothetical protein 3868362 2771667 LIC13156 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003064.1 3868165 R 267671 CDS YP_003065.1 45658979 2772725 3868354..3869286 1 NC_005823.1 hypothetical protein 3869286 2772725 LIC13157 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003065.1 3868354 D 267671 CDS YP_003066.1 45658980 2770722 3869552..3869740 1 NC_005823.1 hypothetical protein 3869740 2770722 LIC13158 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003066.1 3869552 D 267671 CDS YP_003067.1 45658981 2770865 3870289..3870597 1 NC_005823.1 transposase, ISlin1 3870597 2770865 LIC13159 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_003067.1 3870289 D 267671 CDS YP_003068.1 45658982 2771569 3870611..3871216 1 NC_005823.1 transposase, ISlin1 3871216 2771569 LIC13160 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_003068.1 3870611 D 267671 CDS YP_003069.1 45658983 2770087 3871222..3871581 1 NC_005823.1 transposase, ISlin1 3871581 2770087 LIC13161 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, ISlin1 YP_003069.1 3871222 D 267671 CDS YP_003070.1 45658984 2770013 complement(3872009..3873151) 1 NC_005823.1 phospho-2-dehydro-3-deoxyheptonate aldolase chorismate mutase 3873151 aroA(G) 2770013 aroA(G) Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phospho-2-dehydro-3-deoxyheptonate aldolase chorismate mutase YP_003070.1 3872009 R 267671 CDS YP_003071.1 45658985 2772838 complement(3873226..3874023) 1 NC_005823.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 3874023 panB 2772838 panB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_003071.1 3873226 R 267671 CDS YP_003072.1 45658986 2771168 complement(3874007..3874456) 1 NC_005823.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 3874456 folK 2771168 folK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_003072.1 3874007 R 267671 CDS YP_003073.1 45658987 2771612 complement(3874453..3875310) 1 NC_005823.1 DNA replication protein DnaC 3875310 dnaC 2771612 dnaC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA replication protein DnaC YP_003073.1 3874453 R 267671 CDS YP_003074.1 45658988 2771353 3875998..3876918 1 NC_005823.1 hypothetical protein 3876918 2771353 LIC13166 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003074.1 3875998 D 267671 CDS YP_003075.1 45658989 2772323 3877772..3878170 1 NC_005823.1 hypothetical protein 3878170 2772323 LIC13167 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003075.1 3877772 D 267671 CDS YP_003076.1 45658990 2771698 complement(3878864..3879886) 1 NC_005823.1 nodulation protein noel; GDP-mannose 4,6-dehydratase 3879886 gmd 2771698 gmd Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GDP-mannose 4,6-dehydratase YP_003076.1 3878864 R 267671 CDS YP_003077.1 45658991 2772478 complement(3879930..3881351) 1 NC_005823.1 drug: Na+ antiporter; hypothetical protein 3881351 norM 2772478 norM Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003077.1 3879930 R 267671 CDS YP_003078.1 45658992 2769890 complement(3881790..3882317) 1 NC_005823.1 hypothetical protein 3882317 2769890 LIC13170 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003078.1 3881790 R 267671 CDS YP_003079.1 45658993 2772314 3882926..3883150 1 NC_005823.1 hypothetical protein 3883150 2772314 LIC13171 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003079.1 3882926 D 267671 CDS YP_003080.1 45658994 2772088 3883164..3884423 1 NC_005823.1 hypothetical protein 3884423 2772088 LIC13172 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003080.1 3883164 D 267671 CDS YP_003081.1 45658995 2770704 3884590..3885507 1 NC_005823.1 hypothetical protein 3885507 2770704 LIC13173 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003081.1 3884590 D 267671 CDS YP_003082.1 45658996 2771038 3885507..3887306 1 NC_005823.1 potassium uptake protein; KtrB 3887306 ktrB 2771038 ktrB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 KtrB YP_003082.1 3885507 D 267671 CDS YP_003083.1 45658997 2771988 3887319..3888029 1 NC_005823.1 potassium uptake system protein 3888029 trkA 2771988 trkA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 potassium uptake system protein YP_003083.1 3887319 D 267671 CDS YP_003084.1 45658998 2772021 complement(3888014..3889081) 1 NC_005823.1 oxidoreductase; hypothetical protein 3889081 tas 2772021 tas Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003084.1 3888014 R 267671 CDS YP_003085.1 45658999 2771997 3889551..3891122 1 NC_005823.1 exonuclease 3891122 2771997 LIC13177 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 exonuclease YP_003085.1 3889551 D 267671 CDS YP_003086.1 45659000 2770592 complement(3891148..3891435) 1 NC_005823.1 acylphosphatase 3891435 acyP 2770592 acyP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acylphosphatase YP_003086.1 3891148 R 267671 CDS YP_003087.1 45659001 2772855 complement(3891425..3891862) 1 NC_005823.1 globin 3891862 2772855 LIC13179 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 globin YP_003087.1 3891425 R 267671 CDS YP_003088.1 45659002 2769925 complement(3891862..3892350) 1 NC_005823.1 (di)nucleoside polyphosphate hydrolase 3892350 nudH 2769925 nudH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 (di)nucleoside polyphosphate hydrolase YP_003088.1 3891862 R 267671 CDS YP_003089.1 45659003 2770015 3892897..3893328 1 NC_005823.1 SET domain-containing protein 3893328 2770015 LIC13181 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 SET domain-containing protein YP_003089.1 3892897 D 267671 CDS YP_003090.1 45659004 2770641 complement(3893751..3894539) 1 NC_005823.1 glycerophosphoryl diester phosphodiesterase 3894539 ugpQ 2770641 ugpQ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycerophosphoryl diester phosphodiesterase YP_003090.1 3893751 R 267671 CDS YP_003091.1 45659005 2772154 complement(3894674..3895057) 1 NC_005823.1 methyl-accepting chemotaxis-like 3895057 2772154 LIC13183 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methyl-accepting chemotaxis-like YP_003091.1 3894674 R 267671 CDS YP_003092.1 45659006 2771412 complement(3896135..3897235) 1 NC_005823.1 membrane-bound lytic murein transglycosylase A transmembrane protein 3897235 mltA 2771412 mltA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 membrane-bound lytic murein transglycosylase A transmembrane protein YP_003092.1 3896135 R 267671 CDS YP_003093.1 45659007 2772675 complement(3897338..3898942) 1 NC_005823.1 AraC family transcriptional regulator 3898942 2772675 LIC13185 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 AraC family transcriptional regulator YP_003093.1 3897338 R 267671 CDS YP_003094.1 45659008 2769772 complement(3899524..3900024) 1 NC_005823.1 hypothetical protein 3900024 2769772 LIC13186 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003094.1 3899524 R 267671 CDS YP_003095.1 45659009 2771003 complement(3900969..3902438) 1 NC_005823.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 3902438 nhaP 2771003 nhaP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 potassium/proton antiporter YP_003095.1 3900969 R 267671 CDS YP_003096.1 45659010 2772786 complement(3902915..3903130) 1 NC_005823.1 hypothetical protein 3903130 2772786 LIC13188 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003096.1 3902915 R 267671 CDS YP_003097.1 45659011 2769571 complement(3903152..3903607) 1 NC_005823.1 GNAT family; identified by sequence similarity; ORF located using Blastx/Glimmer; acetyltransferase 3903607 wecD 2769571 wecD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyltransferase YP_003097.1 3903152 R 267671 CDS YP_003098.1 45659012 2769728 complement(3904276..3905562) 1 NC_005823.1 hypothetical protein 3905562 2769728 LIC13190 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003098.1 3904276 R 267671 CDS YP_003099.1 45659013 2769489 3905670..3907367 1 NC_005823.1 hypothetical protein 3907367 2769489 LIC13191 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003099.1 3905670 D 267671 CDS YP_003100.1 45659014 2769593 complement(3907493..3909961) 1 NC_005823.1 histidine kinase response regulator hybrid protein 3909961 2769593 LIC13192 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase response regulator hybrid protein YP_003100.1 3907493 R 267671 CDS YP_003101.1 45659015 2769624 complement(3910317..3911396) 1 NC_005823.1 hypothetical protein 3911396 2769624 LIC13193 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003101.1 3910317 R 267671 CDS YP_003102.1 45659016 2769658 3912362..3915769 1 NC_005823.1 cholesterol oxidase 3915769 choB 2769658 choB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cholesterol oxidase YP_003102.1 3912362 D 267671 CDS YP_003103.1 45659017 2769776 3915816..3917384 1 NC_005823.1 cholesterol oxidase precursor 3917384 2769776 LIC13195 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cholesterol oxidase precursor YP_003103.1 3915816 D 267671 CDS YP_003104.1 45659018 2769557 3917675..3918415 1 NC_005823.1 O-methyl transferase 3918415 encK 2769557 encK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 O-methyl transferase YP_003104.1 3917675 D 267671 CDS YP_003105.1 45659019 2769807 complement(3919201..3919869) 1 NC_005823.1 hypothetical protein 3919869 2769807 LIC13197 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003105.1 3919201 R 267671 CDS YP_003106.1 45659020 2769794 3920333..3922009 1 NC_005823.1 hemolysin/sphingomyelinase-like 3922009 2769794 LIC13198 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hemolysin/sphingomyelinase-like YP_003106.1 3920333 D 267671 CDS YP_003107.1 45659021 2771317 3922370..3923020 1 NC_005823.1 hypothetical protein 3923020 2771317 LIC13199 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003107.1 3922370 D 267671 CDS YP_003108.1 45659022 2771904 3923118..3923492 1 NC_005823.1 hypothetical protein 3923492 2771904 LIC13200 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003108.1 3923118 D 267671 CDS YP_003109.1 45659023 2771671 complement(3924332..3928528) 1 NC_005823.1 adenylate/guanylate cyclase 3928528 2771671 LIC13201 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_003109.1 3924332 R 267671 CDS YP_003110.1 45659024 2772737 complement(3928836..3930560) 1 NC_005823.1 cholesterol oxidase precursor 3930560 choD 2772737 choD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cholesterol oxidase precursor YP_003110.1 3928836 R 267671 CDS YP_003111.1 45659025 2771247 complement(3930589..3931035) 1 NC_005823.1 hypothetical protein 3931035 2771247 LIC13203 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003111.1 3930589 R 267671 CDS YP_003112.1 45659026 2770223 complement(3931020..3932033) 1 NC_005823.1 hypothetical protein 3932033 2770223 LIC13204 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003112.1 3931020 R 267671 CDS YP_003113.1 45659027 2771555 3933618..3934544 1 NC_005823.1 heavy metal efflux pump 3934544 2771555 LIC13205 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heavy metal efflux pump YP_003113.1 3933618 D 267671 CDS YP_003114.1 45659028 2770732 complement(3935031..3935498) 1 NC_005823.1 hypothetical protein 3935498 2770732 LIC13206 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003114.1 3935031 R 267671 CDS YP_003115.1 45659029 2772399 complement(3936070..3936702) 1 NC_005823.1 penicillin-binding protein; membrane carboxypeptidase 3936702 2772399 LIC13207 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 membrane carboxypeptidase YP_003115.1 3936070 R 267671 CDS YP_003116.1 45659030 2772174 complement(3937118..3937786) 1 NC_005823.1 riboflavin-specific deaminase/reductase 3937786 2772174 LIC13208 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 riboflavin-specific deaminase/reductase YP_003116.1 3937118 R 267671 CDS YP_003117.1 45659031 2772302 complement(3937783..3938010) 1 NC_005823.1 bacterioferritin-associated ferredoxin 3938010 2772302 LIC13209 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 bacterioferritin-associated ferredoxin YP_003117.1 3937783 R 267671 CDS YP_003118.1 45659032 2771716 3938160..3939497 1 NC_005823.1 major facilitator superfamily permease 3939497 2771716 LIC13210 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 major facilitator superfamily permease YP_003118.1 3938160 D 267671 CDS YP_003119.1 45659033 2772074 3939613..3939822 1 NC_005823.1 hypothetical protein 3939822 2772074 LIC13211 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003119.1 3939613 D 267671 CDS YP_003120.1 45659034 2772233 complement(3940560..3941396) 1 NC_005823.1 hypothetical protein 3941396 2772233 LIC13212 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003120.1 3940560 R 267671 CDS YP_003121.1 45659035 2772746 3941399..3942667 1 NC_005823.1 hypothetical protein 3942667 2772746 LIC13213 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003121.1 3941399 D 267671 CDS YP_003122.1 45659036 2770638 3942741..3943325 1 NC_005823.1 cytochrome oxidase subunit 3943325 2770638 LIC13214 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytochrome oxidase subunit YP_003122.1 3942741 D 267671 CDS YP_003123.1 45659037 2771860 3944351..3945034 1 NC_005823.1 lipoprotein 3945034 2771860 LIC13215 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003123.1 3944351 D 267671 CDS YP_003124.1 45659038 2772710 3945735..3946337 1 NC_005823.1 hypothetical protein 3946337 2772710 LIC13216 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003124.1 3945735 D 267671 CDS YP_003125.1 45659039 2772005 complement(3946638..3946943) 1 NC_005823.1 hypothetical protein 3946943 2772005 LIC13217 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003125.1 3946638 R 267671 CDS YP_003126.1 45659040 2770056 complement(3947330..3947899) 1 NC_005823.1 isoleucine patch superfamily; identified by sequence similarity; ORF located using Blastx/Glimmer; carbonic anhydrase/acetyltransferase 3947899 2770056 LIC13218 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 carbonic anhydrase/acetyltransferase YP_003126.1 3947330 R 267671 CDS YP_003127.2 304570505 2772455 complement(3948506..3950932) 1 NC_005823.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 3950932 pheT 2772455 pheT Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phenylalanyl-tRNA synthetase subunit beta YP_003127.2 3948506 R 267671 CDS YP_003128.1 45659042 2770211 complement(3951011..3953857) 1 NC_005823.1 ATP-dependent RNA helicase 3953857 hepA 2770211 hepA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent RNA helicase YP_003128.1 3951011 R 267671 CDS YP_003129.1 45659043 2770574 complement(3953858..3954589) 1 NC_005823.1 Fe-S oxidoreductase 3954589 2770574 LIC13221 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Fe-S oxidoreductase YP_003129.1 3953858 R 267671 CDS YP_003130.1 45659044 2771014 3954997..3955968 1 NC_005823.1 lauroyl/myristoyl acyltransferase 3955968 htrB 2771014 htrB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lauroyl/myristoyl acyltransferase YP_003130.1 3954997 D 267671 CDS YP_003131.1 45659045 2772569 complement(3956832..3957368) 1 NC_005823.1 inorganic pyrophosphatase 3957368 ppa 2772569 ppa Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 inorganic pyrophosphatase YP_003131.1 3956832 R 267671 CDS YP_003132.1 45659046 2771191 complement(3957426..3958757) 1 NC_005823.1 glycerol-3-phosphate Pi antiporter 3958757 glpT 2771191 glpT Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycerol-3-phosphate Pi antiporter YP_003132.1 3957426 R 267671 CDS YP_003133.1 45659047 2770647 complement(3958852..3959049) 1 NC_005823.1 hypothetical protein 3959049 2770647 LIC13225 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003133.1 3958852 R 267671 CDS YP_003134.1 45659048 2772534 complement(3959068..3959382) 1 NC_005823.1 hypothetical protein 3959382 2772534 LIC13226 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003134.1 3959068 R 267671 CDS YP_003135.1 45659049 2771958 3959718..3960410 1 NC_005823.1 hypothetical protein 3960410 2771958 LIC13227 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003135.1 3959718 D 267671 CDS YP_003136.1 45659050 2772460 3961608..3961820 1 NC_005823.1 hypothetical protein 3961820 2772460 LIC13228 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003136.1 3961608 D 267671 CDS YP_003137.1 45659051 2772599 3962606..3964414 1 NC_005823.1 hypothetical protein 3964414 2772599 LIC13229 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003137.1 3962606 D 267671 CDS YP_003138.1 45659052 2772237 3965016..3966581 1 NC_005823.1 ATP-dependent RNA helicase 3966581 dead 2772237 dead Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent RNA helicase YP_003138.1 3965016 D 267671 CDS YP_003139.1 45659053 2770136 3966708..3968021 1 NC_005823.1 hypothetical protein 3968021 2770136 LIC13231 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003139.1 3966708 D 267671 CDS YP_003140.1 45659054 2772510 complement(3968900..3969700) 1 NC_005823.1 short-chain dehydrogenase 3969700 2772510 LIC13232 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 short-chain dehydrogenase YP_003140.1 3968900 R 267671 CDS YP_003141.1 45659055 2772485 3969851..3970489 1 NC_005823.1 hypothetical protein 3970489 2772485 LIC13233 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003141.1 3969851 D 267671 CDS YP_003142.1 45659056 2772367 3970729..3971652 1 NC_005823.1 malate permease 3971652 2772367 LIC13235 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 malate permease YP_003142.1 3970729 D 267671 CDS YP_003143.2 304570506 2770251 3971598..3972752 1 NC_005823.1 ankyrin 3972752 arp 2770251 arp Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ankyrin YP_003143.2 3971598 D 267671 CDS YP_003144.1 45659058 2772362 complement(3973786..3974343) 1 NC_005823.1 hypothetical protein 3974343 2772362 LIC13237 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003144.1 3973786 R 267671 CDS YP_003145.1 45659059 2770658 3974609..3975766 1 NC_005823.1 hypothetical protein 3975766 2770658 LIC13238 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003145.1 3974609 D 267671 CDS YP_003146.1 45659060 2770758 complement(3976430..3976951) 1 NC_005823.1 hypothetical protein 3976951 2770758 LIC13239 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003146.1 3976430 R 267671 CDS YP_003147.2 161621771 2772711 3977113..3977919 1 NC_005823.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 3977919 mazG 2772711 mazG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 nucleoside triphosphate pyrophosphohydrolase YP_003147.2 3977113 D 267671 CDS YP_003148.1 45659062 2772506 3977889..3978296 1 NC_005823.1 hypothetical protein 3978296 2772506 LIC13241 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003148.1 3977889 D 267671 CDS YP_003149.1 45659063 2772732 3978293..3979063 1 NC_005823.1 response regulator 3979063 2772732 LIC13242 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_003149.1 3978293 D 267671 CDS YP_003150.1 45659064 2770698 complement(3979060..3979602) 1 NC_005823.1 hypothetical protein 3979602 2770698 LIC13243 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003150.1 3979060 R 267671 CDS YP_003151.1 45659065 2770121 complement(3979829..3981025) 1 NC_005823.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 3981025 icdA 2770121 icdA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 isocitrate dehydrogenase YP_003151.1 3979829 R 267671 CDS YP_003152.1 45659066 2770297 complement(3981094..3981747) 1 NC_005823.1 hypothetical protein 3981747 2770297 LIC13245 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003152.1 3981094 R 267671 CDS YP_003153.1 45659067 2770427 3981958..3982377 1 NC_005823.1 hypothetical protein 3982377 2770427 LIC13246 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003153.1 3981958 D 267671 CDS YP_003154.1 45659068 2770017 3982409..3983524 1 NC_005823.1 hypothetical protein 3983524 2770017 LIC13247 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003154.1 3982409 D 267671 CDS YP_003155.1 45659069 2770124 complement(3983966..3985360) 1 NC_005823.1 lipoprotein 3985360 2770124 LIC13248 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003155.1 3983966 R 267671 CDS YP_003156.1 45659070 2771195 complement(3986467..3986955) 1 NC_005823.1 hypothetical protein 3986955 2771195 LIC13249 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003156.1 3986467 R 267671 CDS YP_003157.1 45659071 2771520 complement(3987104..3988933) 1 NC_005823.1 apolipoprotein n-acyltransferase 3988933 2771520 LIC13250 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 apolipoprotein n-acyltransferase YP_003157.1 3987104 R 267671 CDS YP_003158.1 45659072 2770304 3989142..3990440 1 NC_005823.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3990440 murA 2770304 murA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_003158.1 3989142 D 267671 CDS YP_003159.1 45659073 2770949 3990437..3991093 1 NC_005823.1 methylamine utilization ferredoxin-type protein 3991093 mauM 2770949 mauM Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methylamine utilization ferredoxin-type protein YP_003159.1 3990437 D 267671 CDS YP_003160.1 45659074 2771045 3991135..3991506 1 NC_005823.1 internal repeat sequences detected; contains Cysteine rich repeat as detected by pfam-hmmr; hypothetical protein 3991506 2771045 LIC13253 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003160.1 3991135 D 267671 CDS YP_003161.1 45659075 2771123 complement(3992714..3993202) 1 NC_005823.1 hypothetical protein 3993202 2771123 LIC13254 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003161.1 3992714 R 267671 CDS YP_003162.1 45659076 2771812 complement(3993212..3993547) 1 NC_005823.1 lipoprotein 3993547 2771812 LIC13255 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003162.1 3993212 R 267671 CDS YP_003163.1 45659077 2770788 complement(3994014..3994586) 1 NC_005823.1 lipoprotein 3994586 2770788 LIC13256 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003163.1 3994014 R 267671 CDS YP_003164.1 45659078 2771937 complement(3994570..3995592) 1 NC_005823.1 NADH oxidoreductase 3995592 2771937 LIC13257 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH oxidoreductase YP_003164.1 3994570 R 267671 CDS YP_003165.1 45659079 2769863 complement(3995589..3995915) 1 NC_005823.1 ferredoxin 3995915 fdx 2769863 fdx Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ferredoxin YP_003165.1 3995589 R 267671 CDS YP_003166.1 45659080 2770987 3996309..3996803 1 NC_005823.1 lipoprotein 3996803 2770987 LIC13259 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003166.1 3996309 D 267671 CDS YP_003167.1 45659081 2772029 3996782..3997771 1 NC_005823.1 hypothetical protein 3997771 2772029 LIC13260 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003167.1 3996782 D 267671 CDS YP_003168.1 45659082 2772276 complement(3997780..3998604) 1 NC_005823.1 hypothetical protein 3998604 2772276 LIC13261 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003168.1 3997780 R 267671 CDS YP_003169.1 45659083 2771281 complement(3999615..4001087) 1 NC_005823.1 glutamine phosphoribosylpyrophosphate amidotransferase 4001087 purF 2771281 purF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutamine phosphoribosylpyrophosphate amidotransferase YP_003169.1 3999615 R 267671 CDS YP_003170.1 45659084 2772166 4001129..4002295 1 NC_005823.1 ribonuclease D 4002295 rnD 2772166 rnD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ribonuclease D YP_003170.1 4001129 D 267671 CDS YP_003171.1 45659085 2771064 4002327..4002998 1 NC_005823.1 MutT nudix family protein 4002998 2771064 LIC13264 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 MutT nudix family protein YP_003171.1 4002327 D 267671 CDS YP_003172.1 45659086 2772500 4004897..4005292 1 NC_005823.1 hypothetical protein 4005292 2772500 LIC13265 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003172.1 4004897 D 267671 CDS YP_003173.1 45659087 2770008 4005292..4005870 1 NC_005823.1 RNA polymerase ECF-type sigma factor 4005870 2770008 LIC13266 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA polymerase ECF-type sigma factor YP_003173.1 4005292 D 267671 CDS YP_003174.1 45659088 2772321 4005854..4006225 1 NC_005823.1 hypothetical protein 4006225 2772321 LIC13267 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003174.1 4005854 D 267671 CDS YP_003175.1 45659089 2770836 4006222..4006668 1 NC_005823.1 hypothetical protein 4006668 2770836 LIC13268 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003175.1 4006222 D 267671 CDS YP_003176.1 45659090 2772136 4007977..4008678 1 NC_005823.1 response regulator 4008678 2772136 LIC13269 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_003176.1 4007977 D 267671 CDS YP_003177.1 45659091 2772600 4008668..4010059 1 NC_005823.1 histidine kinase sensor protein 4010059 2772600 LIC13270 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_003177.1 4008668 D 267671 CDS YP_003178.1 45659092 2772095 4010128..4011285 1 NC_005823.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 4011285 argJ 2772095 argJ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein YP_003178.1 4010128 D 267671 CDS YP_003179.1 45659093 2772541 4011266..4012570 1 NC_005823.1 hypothetical protein 4012570 2772541 LIC13272 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003179.1 4011266 D 267671 CDS YP_003180.1 45659094 2772264 4012567..4014945 1 NC_005823.1 sigma factor regulatory protein 4014945 2772264 LIC13273 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sigma factor regulatory protein YP_003180.1 4012567 D 267671 CDS YP_003181.1 45659095 2771934 complement(4015299..4015985) 1 NC_005823.1 hypothetical protein 4015985 2771934 LIC13274 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003181.1 4015299 R 267671 CDS YP_003182.1 45659096 2770731 complement(4016190..4017314) 1 NC_005823.1 hypothetical protein 4017314 2770731 LIC13275 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003182.1 4016190 R 267671 CDS YP_003183.1 45659097 2770301 complement(4017311..4017565) 1 NC_005823.1 hypothetical protein 4017565 2770301 LIC13276 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003183.1 4017311 R 267671 CDS YP_003184.1 45659098 2770035 4018500..4018796 1 NC_005823.1 hypothetical protein 4018796 2770035 LIC13277 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003184.1 4018500 D 267671 CDS YP_003185.1 45659099 2770847 complement(4018901..4019257) 1 NC_005823.1 hypothetical protein 4019257 2770847 LIC13278 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003185.1 4018901 R 267671 CDS YP_003186.1 45659100 2769796 complement(4019277..4020800) 1 NC_005823.1 acetyl CoA acetyltransferase 4020800 2769796 LIC13279 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyl CoA acetyltransferase YP_003186.1 4019277 R 267671 CDS YP_003187.1 45659101 2770324 complement(4021077..4021526) 1 NC_005823.1 MaoC family protein 4021526 2770324 LIC13280 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 MaoC family protein YP_003187.1 4021077 R 267671 CDS YP_003188.1 45659102 2772728 complement(4022356..4023960) 1 NC_005823.1 acyl-CoA dehydrogenase 4023960 2772728 LIC13281 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyl-CoA dehydrogenase YP_003188.1 4022356 R 267671 CDS YP_003189.1 45659103 2771889 complement(4024999..4027044) 1 NC_005823.1 NAD dependent DNA ligase 4027044 lig 2771889 lig Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NAD dependent DNA ligase YP_003189.1 4024999 R 267671 CDS YP_003190.1 45659104 2771639 complement(4027063..4028034) 1 NC_005823.1 hypothetical protein 4028034 2771639 LIC13283 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003190.1 4027063 R 267671 CDS YP_003191.1 45659105 2771975 complement(4028315..4028674) 1 NC_005823.1 hypothetical protein 4028674 2771975 LIC13284 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003191.1 4028315 R 267671 CDS YP_003192.1 45659106 2769951 complement(4028692..4029201) 1 NC_005823.1 RNA polymerase ECF-type sigma factor 4029201 2769951 LIC13285 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA polymerase ECF-type sigma factor YP_003192.1 4028692 R 267671 CDS YP_003193.1 45659107 2772623 complement(4029209..4029790) 1 NC_005823.1 hypothetical protein 4029790 2772623 LIC13286 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003193.1 4029209 R 267671 CDS YP_003194.1 45659108 2771583 4029923..4030615 1 NC_005823.1 vancomycin resistance protein 4030615 sanA 2771583 sanA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 vancomycin resistance protein YP_003194.1 4029923 D 267671 CDS YP_003195.1 45659109 2771719 complement(4031940..4033073) 1 NC_005823.1 histidine kinase sensor protein 4033073 2771719 LIC13288 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_003195.1 4031940 R 267671 CDS YP_003196.1 45659110 2770422 complement(4033278..4034408) 1 NC_005823.1 histidine kinase sensor protein 4034408 2770422 LIC13289 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_003196.1 4033278 R 267671 CDS YP_003197.1 45659111 2771183 complement(4034804..4035145) 1 NC_005823.1 hypothetical protein 4035145 2771183 LIC13290 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003197.1 4034804 R 267671 CDS YP_003198.1 45659112 2772596 complement(4035142..4035654) 1 NC_005823.1 ankyrin 4035654 2772596 LIC13291 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ankyrin YP_003198.1 4035142 R 267671 CDS YP_003199.1 45659113 2769877 4036193..4036720 1 NC_005823.1 hypothetical protein 4036720 2769877 LIC13292 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003199.1 4036193 D 267671 CDS YP_003200.1 45659114 2769977 4037281..4039260 1 NC_005823.1 hypothetical protein 4039260 2769977 LIC13293 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003200.1 4037281 D 267671 CDS YP_003201.1 45659115 2770849 4039295..4039495 1 NC_005823.1 hypothetical protein 4039495 2770849 LIC13294 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003201.1 4039295 D 267671 CDS YP_003202.1 45659116 2770525 4040189..4040716 1 NC_005823.1 hypothetical protein 4040716 2770525 LIC13295 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003202.1 4040189 D 267671 CDS YP_003203.1 45659117 2771929 complement(4041434..4044022) 1 NC_005823.1 lipoprotein 4044022 2771929 LIC13296 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003203.1 4041434 R 267671 CDS YP_003204.1 45659118 2769911 4045382..4045783 1 NC_005823.1 hypothetical protein 4045783 2769911 LIC13297 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003204.1 4045382 D 267671 CDS YP_003205.1 45659119 2772593 4046951..4048261 1 NC_005823.1 3-hydroxyacyl-CoA dehydrogenase 4048261 fadB 2772593 fadB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-hydroxyacyl-CoA dehydrogenase YP_003205.1 4046951 D 267671 CDS YP_003206.1 45659120 2770267 4048277..4049542 1 NC_005823.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 4049542 2770267 LIC13301 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyl-CoA acetyltransferase YP_003206.1 4048277 D 267671 CDS YP_003207.1 45659121 2772254 4049545..4049982 1 NC_005823.1 hypothetical protein 4049982 2772254 LIC13302 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003207.1 4049545 D 267671 CDS YP_003208.1 45659122 2770822 complement(4050713..4051627) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 4051627 2770822 LIC13303 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003208.1 4050713 R 267671 CDS YP_003209.1 45659123 2772544 complement(4051956..4052141) 1 NC_005823.1 hypothetical protein 4052141 2772544 LIC13304 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003209.1 4051956 R 267671 CDS YP_003210.1 45659124 2770952 4052203..4053078 1 NC_005823.1 lipoprotein 4053078 2770952 LIC13305 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003210.1 4052203 D 267671 CDS YP_003211.1 45659125 2770143 complement(4053145..4053687) 1 NC_005823.1 internal repeat sequences detected; contains MORN repeat as detected by pfam-hmmr; hypothetical protein 4053687 2770143 LIC13306 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003211.1 4053145 R 267671 CDS YP_003212.1 45659126 2772301 complement(4053841..4054050) 1 NC_005823.1 hypothetical protein 4054050 2772301 LIC13307 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003212.1 4053841 R 267671 CDS YP_003213.1 45659127 2770966 4054667..4055545 1 NC_005823.1 hypothetical protein 4055545 2770966 LIC13308 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003213.1 4054667 D 267671 CDS YP_003214.1 45659128 2772395 complement(4057108..4057521) 1 NC_005823.1 4-hydroxybenzoyl-CoA thioesterase 4057521 2772395 LIC13309 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 4-hydroxybenzoyl-CoA thioesterase YP_003214.1 4057108 R 267671 CDS YP_003215.1 45659129 2771268 complement(4057523..4058548) 1 NC_005823.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 4058548 pheS 2771268 pheS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phenylalanyl-tRNA synthetase subunit alpha YP_003215.1 4057523 R 267671 CDS YP_003216.1 45659130 2771969 complement(4058545..4059942) 1 NC_005823.1 UDP-n-acetylmuramate:l-alanyl-gamma-d-glutamyl- meso- diaminopimelate ligase 4059942 mpl 2771969 mpl Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-n-acetylmuramate:l-alanyl-gamma-d-glutamyl- meso- diaminopimelate ligase YP_003216.1 4058545 R 267671 CDS YP_003217.1 45659131 2772383 complement(4059939..4060556) 1 NC_005823.1 hypothetical protein 4060556 2772383 LIC13312 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003217.1 4059939 R 267671 CDS YP_003218.1 45659132 2769872 complement(4060543..4061646) 1 NC_005823.1 hypothetical protein 4061646 2769872 LIC13313 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003218.1 4060543 R 267671 CDS YP_003219.1 45659133 2770026 complement(4061643..4063670) 1 NC_005823.1 hypothetical protein 4063670 2770026 LIC13314 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003219.1 4061643 R 267671 CDS YP_003220.1 45659134 2771984 complement(4063658..4064386) 1 NC_005823.1 ABC transporter permease 4064386 2771984 LIC13315 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter permease YP_003220.1 4063658 R 267671 CDS YP_003221.1 45659135 2772739 complement(4064391..4065320) 1 NC_005823.1 ABC transporter ATP-binding protein 4065320 2772739 LIC13316 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_003221.1 4064391 R 267671 CDS YP_003222.1 45659136 2771067 complement(4065708..4066490) 1 NC_005823.1 hypothetical protein 4066490 2771067 LIC13317 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003222.1 4065708 R 267671 CDS YP_003223.1 45659137 2771486 4066637..4067794 1 NC_005823.1 fatty acid synthase subunit beta 4067794 fas1 2771486 fas1 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 fatty acid synthase subunit beta YP_003223.1 4066637 D 267671 CDS YP_003224.1 45659138 2770232 4068133..4069356 1 NC_005823.1 hypothetical protein 4069356 2770232 LIC13319 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003224.1 4068133 D 267671 CDS YP_003225.1 45659139 2771365 complement(4069685..4072060) 1 NC_005823.1 thermolysin precursor 4072060 2771365 LIC13320 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thermolysin precursor YP_003225.1 4069685 R 267671 CDS YP_003226.1 45659140 2772129 complement(4073098..4075476) 1 NC_005823.1 thermolysin homolog precursor 4075476 2772129 LIC13321 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thermolysin homolog precursor YP_003226.1 4073098 R 267671 CDS YP_003227.1 45659141 2770759 complement(4076605..4078989) 1 NC_005823.1 thermolysin precursor 4078989 nprT 2770759 nprT Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thermolysin precursor YP_003227.1 4076605 R 267671 CDS YP_003228.1 45659142 2772472 complement(4079670..4079861) 1 NC_005823.1 hypothetical protein 4079861 2772472 LIC13323 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003228.1 4079670 R 267671 CDS YP_003229.1 45659143 2772368 4079853..4081064 1 NC_005823.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; citrulline-aspartate ligase; argininosuccinate synthase 4081064 argG 2772368 argG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 argininosuccinate synthase YP_003229.1 4079853 D 267671 CDS YP_003230.1 45659144 2771525 4081061..4081543 1 NC_005823.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4081543 coaD 2771525 coaD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphopantetheine adenylyltransferase YP_003230.1 4081061 D 267671 CDS YP_003231.1 45659145 2769904 4081553..4081966 1 NC_005823.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 4081966 ndk 2769904 ndk Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 nucleoside diphosphate kinase YP_003231.1 4081553 D 267671 CDS YP_003232.1 45659146 2770561 4082435..4082623 1 NC_005823.1 hypothetical protein 4082623 2770561 LIC13327 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003232.1 4082435 D 267671 CDS YP_003233.1 45659147 2771541 4083538..4085004 1 NC_005823.1 catalyzes the formation of 2-oxoglutarate from isocitrate; isocitrate dehydrogenase 4085004 2771541 LIC13328 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 isocitrate dehydrogenase YP_003233.1 4083538 D 267671 CDS YP_003234.1 45659148 2771523 4085217..4085648 1 NC_005823.1 hypothetical protein 4085648 2771523 LIC13329 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003234.1 4085217 D 267671 CDS YP_003235.1 45659149 2770685 complement(4086177..4086587) 1 NC_005823.1 response regulator 4086587 2770685 LIC13330 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_003235.1 4086177 R 267671 CDS YP_003236.1 45659150 2772194 complement(4086571..4088130) 1 NC_005823.1 histidine kinase sensor protein 4088130 2772194 LIC13331 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_003236.1 4086571 R 267671 CDS YP_003237.1 45659151 2771711 complement(4088626..4088868) 1 NC_005823.1 ferredoxin 4088868 2771711 LIC13332 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ferredoxin YP_003237.1 4088626 R 267671 CDS YP_003238.1 45659152 2770776 4088949..4089515 1 NC_005823.1 hypothetical protein 4089515 2770776 LIC13333 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003238.1 4088949 D 267671 CDS YP_003239.1 45659153 2771766 4089512..4091068 1 NC_005823.1 GMC oxidoreductase 4091068 2771766 LIC13334 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GMC oxidoreductase YP_003239.1 4089512 D 267671 CDS YP_003240.1 45659154 2771332 4091720..4091959 1 NC_005823.1 hypothetical protein 4091959 2771332 LIC13335 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003240.1 4091720 D 267671 CDS YP_003241.1 45659155 2772042 4091956..4093134 1 NC_005823.1 aminotransferase 4093134 2772042 LIC13336 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aminotransferase YP_003241.1 4091956 D 267671 CDS YP_003242.1 45659156 2770888 complement(4094180..4095172) 1 NC_005823.1 zinc carboxypeptidase-related protein 4095172 2770888 LIC13337 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 zinc carboxypeptidase-related protein YP_003242.1 4094180 R 267671 CDS YP_003243.1 45659157 2771388 complement(4095181..4095594) 1 NC_005823.1 lipoprotein 4095594 2771388 LIC13338 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003243.1 4095181 R 267671 CDS YP_003244.1 45659158 2771477 complement(4095606..4096334) 1 NC_005823.1 flagellar motor protein; hypothetical protein 4096334 2771477 LIC13339 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003244.1 4095606 R 267671 CDS YP_003245.1 45659159 2770656 complement(4096331..4096864) 1 NC_005823.1 hypothetical protein 4096864 2770656 LIC13340 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003245.1 4096331 R 267671 CDS YP_003246.1 45659160 2772381 complement(4096978..4098207) 1 NC_005823.1 lipoprotein 4098207 2772381 LIC13341 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003246.1 4096978 R 267671 CDS YP_003247.1 45659161 2771902 complement(4098497..4099024) 1 NC_005823.1 hypothetical protein 4099024 2771902 LIC13342 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003247.1 4098497 R 267671 CDS YP_003248.1 45659162 2771578 complement(4099161..4100021) 1 NC_005823.1 hypothetical protein 4100021 2771578 LIC13343 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003248.1 4099161 R 267671 CDS YP_003249.1 45659163 2772801 complement(4100023..4100610) 1 NC_005823.1 hypothetical protein 4100610 2772801 LIC13344 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003249.1 4100023 R 267671 CDS YP_003250.1 45659164 2771897 complement(4100683..4102248) 1 NC_005823.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 4102248 gltX 2771897 gltX Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutamyl-tRNA synthetase YP_003250.1 4100683 R 267671 CDS YP_003251.1 45659165 2771925 complement(4102245..4103159) 1 NC_005823.1 hypothetical protein 4103159 2771925 LIC13346 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003251.1 4102245 R 267671 CDS YP_003252.1 45659166 2771629 4103363..4104751 1 NC_005823.1 DNA gyrase subunit A 4104751 2771629 LIC13347 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA gyrase subunit A YP_003252.1 4103363 D 267671 CDS YP_003253.1 45659167 2770110 4104748..4106883 1 NC_005823.1 DNA gyrase subunit B 4106883 gyrB 2770110 gyrB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA gyrase subunit B YP_003253.1 4104748 D 267671 CDS YP_003254.1 45659168 2771605 4106944..4107423 1 NC_005823.1 hypothetical protein 4107423 2771605 LIC13349 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003254.1 4106944 D 267671 CDS YP_003255.1 45659169 2770938 4107707..4108558 1 NC_005823.1 flagellar basal-body rod protein; hypothetical protein 4108558 2770938 LIC13350 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003255.1 4107707 D 267671 CDS YP_003256.1 45659170 2771007 complement(4108706..4109677) 1 NC_005823.1 hypothetical protein 4109677 2771007 LIC13351 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003256.1 4108706 R 267671 CDS YP_003257.1 45659171 2770438 4109993..4110196 1 NC_005823.1 hypothetical protein 4110196 2770438 LIC13352 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003257.1 4109993 D 267671 CDS YP_003258.1 45659172 2771377 complement(4110495..4111838) 1 NC_005823.1 L-amino acid oxidase 4111838 lao 2771377 lao Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 L-amino acid oxidase YP_003258.1 4110495 R 267671 CDS YP_003259.1 45659173 2771714 4112445..4113182 1 NC_005823.1 hypothetical protein 4113182 2771714 LIC13354 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003259.1 4112445 D 267671 CDS YP_003260.1 45659174 2769948 4113249..4114076 1 NC_005823.1 lipoprotein 4114076 2769948 LIC13355 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003260.1 4113249 D 267671 CDS YP_003261.1 45659175 2771052 4114237..4115271 1 NC_005823.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 4115271 cobT 2771052 cobT Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_003261.1 4114237 D 267671 CDS YP_003262.1 45659176 2771056 4115268..4116065 1 NC_005823.1 cobalamin 5'-phosphate synthase 4116065 cobS 2771056 cobS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cobalamin 5'-phosphate synthase YP_003262.1 4115268 D 267671 CDS YP_003263.1 45659177 2770998 4116050..4116634 1 NC_005823.1 phosphoglycerate mutase 4116634 gpmB 2770998 gpmB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoglycerate mutase YP_003263.1 4116050 D 267671 CDS YP_003264.1 45659178 2771446 4117133..4118266 1 NC_005823.1 hypothetical protein 4118266 2771446 LIC13359 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003264.1 4117133 D 267671 CDS YP_003265.1 45659179 2771919 complement(4118270..4120105) 1 NC_005823.1 hypothetical protein 4120105 2771919 LIC13360 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003265.1 4118270 R 267671 CDS YP_003266.1 45659180 2771640 complement(4120107..4122194) 1 NC_005823.1 hypothetical protein 4122194 2771640 LIC13361 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003266.1 4120107 R 267671 CDS YP_003267.1 45659181 2771304 complement(4123169..4125016) 1 NC_005823.1 chloride channel 4125016 eriL 2771304 eriL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chloride channel YP_003267.1 4123169 R 267671 CDS YP_003268.1 45659182 2771059 complement(4125799..4126575) 1 NC_005823.1 hypothetical protein 4126575 2771059 LIC13363 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003268.1 4125799 R 267671 CDS YP_003269.1 45659183 2770266 complement(4126572..4127483) 1 NC_005823.1 hypothetical protein 4127483 2770266 LIC13364 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003269.1 4126572 R 267671 CDS YP_003270.1 45659184 2772011 4127456..4128466 1 NC_005823.1 hypothetical protein 4128466 2772011 LIC13365 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003270.1 4127456 D 267671 CDS YP_003271.1 45659185 2769757 4128459..4129535 1 NC_005823.1 strictosidine synthase 4129535 2769757 LIC13366 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 strictosidine synthase YP_003271.1 4128459 D 267671 CDS YP_003272.1 45659186 2769771 complement(4129545..4131230) 1 NC_005823.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 4131230 cysI 2769771 cysI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sulfite reductase subunit beta YP_003272.1 4129545 R 267671 CDS YP_003273.1 45659187 2769683 complement(4131267..4131875) 1 NC_005823.1 siroheme synthetase 4131875 cysG 2769683 cysG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 siroheme synthetase YP_003273.1 4131267 R 267671 CDS YP_003274.1 45659188 2769584 complement(4131865..4132704) 1 NC_005823.1 uroporphyrinogen-III C-methyltransferase 4132704 cobA 2769584 cobA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 uroporphyrinogen-III C-methyltransferase YP_003274.1 4131865 R 267671 CDS YP_003275.1 45659189 2770514 complement(4132708..4133958) 1 NC_005823.1 sulfate adenylyltransferase subunit 1 4133958 cysN 2770514 cysN Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sulfate adenylyltransferase subunit 1 YP_003275.1 4132708 R 267671 CDS YP_003276.1 45659190 2769777 complement(4133958..4134875) 1 NC_005823.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 4134875 cysD 2769777 cysD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sulfate adenylyltransferase subunit 2 YP_003276.1 4133958 R 267671 CDS YP_003277.1 45659191 2770193 complement(4134872..4135612) 1 NC_005823.1 phosphoadenosine phosphosulphate reductase 4135612 cysH 2770193 cysH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoadenosine phosphosulphate reductase YP_003277.1 4134872 R 267671 CDS YP_003278.1 45659192 2769655 complement(4136249..4136449) 1 NC_005823.1 hypothetical protein 4136449 2769655 LIC13373 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003278.1 4136249 R 267671 CDS YP_003279.1 45659193 2769570 4137038..4137343 1 NC_005823.1 IS1500 transposase 4137343 2769570 LIC13374 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 IS1500 transposase YP_003279.1 4137038 D 267671 CDS YP_003280.1 45659194 2769672 4138479..4139837 1 NC_005823.1 FAD-dependent oxiredutase 4139837 2769672 LIC13376 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 FAD-dependent oxiredutase YP_003280.1 4138479 D 267671 CDS YP_003281.1 45659195 2769542 complement(4140791..4141627) 1 NC_005823.1 transposase, IS1501 4141627 2769542 LIC13377 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transposase, IS1501 YP_003281.1 4140791 R 267671 CDS YP_003282.1 45659196 2769485 4142451..4143365 1 NC_005823.1 hypothetical protein; CAAX protease 4143365 2769485 LIC13379 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 CAAX protease YP_003282.1 4142451 D 267671 CDS YP_003283.1 45659197 2769473 4143842..4144060 1 NC_005823.1 hypothetical protein 4144060 2769473 LIC13380 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003283.1 4143842 D 267671 CDS YP_003284.1 45659198 2769541 4144322..4145443 1 NC_005823.1 hypothetical protein 4145443 2769541 LIC13381 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003284.1 4144322 D 267671 CDS YP_003285.1 45659199 2772691 4145545..4146555 1 NC_005823.1 dipeptide ABC transporter permease 4146555 2772691 LIC13382 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dipeptide ABC transporter permease YP_003285.1 4145545 D 267671 CDS YP_003286.1 45659200 2770461 4146552..4147595 1 NC_005823.1 dipeptide ABC transporter permease 4147595 2770461 LIC13383 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dipeptide ABC transporter permease YP_003286.1 4146552 D 267671 CDS YP_003287.1 45659201 2770457 4147592..4148593 1 NC_005823.1 ABC transporter ATP-binding protein 4148593 2770457 LIC13384 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_003287.1 4147592 D 267671 CDS YP_003288.1 45659202 2769753 4148590..4149543 1 NC_005823.1 ABC transporter ATP-binding protein 4149543 2769753 LIC13385 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_003288.1 4148590 D 267671 CDS YP_003289.1 45659203 2770154 4149522..4151603 1 NC_005823.1 hypothetical protein 4151603 2770154 LIC13386 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003289.1 4149522 D 267671 CDS YP_003290.1 45659204 2771873 4151627..4152049 1 NC_005823.1 hypothetical protein 4152049 2771873 LIC13387 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003290.1 4151627 D 267671 CDS YP_003291.1 45659205 2772841 4152430..4152960 1 NC_005823.1 hypothetical protein 4152960 2772841 LIC13388 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003291.1 4152430 D 267671 CDS YP_003292.1 45659206 2772428 complement(4153049..4154881) 1 NC_005823.1 MutS-like; identified by sequence similarity; ORF located using Blastx/Glimmer; DNA mismatch repair protein 4154881 2772428 LIC13389 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA mismatch repair protein YP_003292.1 4153049 R 267671 CDS YP_003293.1 45659207 2770054 complement(4154878..4155114) 1 NC_005823.1 hypothetical protein 4155114 2770054 LIC13390 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003293.1 4154878 R 267671 CDS YP_003294.1 45659208 2772669 4155223..4155459 1 NC_005823.1 hypothetical protein 4155459 2772669 LIC13391 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003294.1 4155223 D 267671 CDS YP_003295.1 45659209 2771564 complement(4155708..4157330) 1 NC_005823.1 polysaccharide deacetylase 4157330 2771564 LIC13392 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 polysaccharide deacetylase YP_003295.1 4155708 R 267671 CDS YP_003296.1 45659210 2769841 complement(4157938..4159062) 1 NC_005823.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4159062 ilvC 2769841 ilvC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ketol-acid reductoisomerase YP_003296.1 4157938 R 267671 CDS YP_003297.1 45659211 2771105 complement(4159953..4161545) 1 NC_005823.1 methyl-accepting chemotaxis transmembrane protein 4161545 dmcA 2771105 dmcA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methyl-accepting chemotaxis transmembrane protein YP_003297.1 4159953 R 267671 CDS YP_003298.1 45659212 2772473 4162224..4162694 1 NC_005823.1 hypothetical protein 4162694 2772473 LIC13395 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003298.1 4162224 D 267671 CDS YP_003299.1 45659213 2771170 4163062..4164495 1 NC_005823.1 flavin-binding family; identified by sequence similarity; ORF located using Blastx/Glimmer; monooxygenase 4164495 2771170 LIC13396 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 monooxygenase YP_003299.1 4163062 D 267671 CDS YP_003300.1 45659214 2772183 4164603..4165934 1 NC_005823.1 phosphodiesterase; alkaline phosphatase 4165934 phoD 2772183 phoD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alkaline phosphatase YP_003300.1 4164603 D 267671 CDS YP_003301.1 45659215 2771165 4165941..4166762 1 NC_005823.1 hypothetical protein 4166762 2771165 LIC13398 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003301.1 4165941 D 267671 CDS YP_003302.1 45659216 2771325 complement(4167417..4168280) 1 NC_005823.1 5'-methylthioadenosine phosphorylase 4168280 mtaP 2771325 mtaP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 5'-methylthioadenosine phosphorylase YP_003302.1 4167417 R 267671 CDS YP_003303.1 45659217 2770918 complement(4168449..4169264) 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 4169264 2770918 LIC13400 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003303.1 4168449 R 267671 CDS YP_003304.1 45659218 2772122 complement(4169584..4171152) 1 NC_005823.1 methyl-accepting chemotaxis protein 4171152 2772122 LIC13401 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methyl-accepting chemotaxis protein YP_003304.1 4169584 R 267671 CDS YP_003305.1 45659219 2771302 complement(4171728..4172558) 1 NC_005823.1 methylated-DNA--protein-cysteine methyltransferase transcription regulator 4172558 ada 2771302 ada Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methylated-DNA--protein-cysteine methyltransferase transcription regulator YP_003305.1 4171728 R 267671 CDS YP_003306.1 45659220 2772187 complement(4172739..4173512) 1 NC_005823.1 iron-binding protein; YvrC 4173512 2772187 LIC13403 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 YvrC YP_003306.1 4172739 R 267671 CDS YP_003307.1 45659221 2769882 complement(4173534..4175519) 1 NC_005823.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4175519 acsA 2769882 acsA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetyl-CoA synthetase YP_003307.1 4173534 R 267671 CDS YP_003308.1 45659222 2772328 complement(4175598..4176149) 1 NC_005823.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 4176149 folE 2772328 folE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GTP cyclohydrolase I YP_003308.1 4175598 R 267671 CDS YP_003309.1 45659223 2771457 4176543..4177754 1 NC_005823.1 mannosyltransferase 4177754 2771457 LIC13406 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 mannosyltransferase YP_003309.1 4176543 D 267671 CDS YP_003310.1 45659224 2772741 complement(4178276..4178764) 1 NC_005823.1 hypothetical protein 4178764 2772741 LIC13407 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003310.1 4178276 R 267671 CDS YP_003311.1 45659225 2771709 complement(4178745..4179098) 1 NC_005823.1 ArsR family transcriptional regulator 4179098 2771709 LIC13408 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ArsR family transcriptional regulator YP_003311.1 4178745 R 267671 CDS YP_003312.1 45659226 2770867 complement(4180311..4181270) 1 NC_005823.1 dTDP-4-dehydrorhamnose 3,5-epimerase 4181270 2770867 LIC13409 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dTDP-4-dehydrorhamnose 3,5-epimerase YP_003312.1 4180311 R 267671 CDS YP_003313.1 45659227 2772310 4181366..4181770 1 NC_005823.1 hypothetical protein 4181770 2772310 LIC13410 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003313.1 4181366 D 267671 CDS YP_003314.1 45659228 2770719 complement(4182149..4182937) 1 NC_005823.1 lipoprotein 4182937 2770719 LIC13411 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003314.1 4182149 R 267671 CDS YP_003315.1 45659229 2771634 4183043..4185472 1 NC_005823.1 glycerol-3-phosphate acyltransferase 4185472 plsB 2771634 plsB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glycerol-3-phosphate acyltransferase YP_003315.1 4183043 D 267671 CDS YP_003316.1 45659230 2771152 complement(4186510..4187673) 1 NC_005823.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 4187673 purT 2771152 purT Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoribosylglycinamide formyltransferase 2 YP_003316.1 4186510 R 267671 CDS YP_003317.1 45659231 2772780 complement(4187830..4188873) 1 NC_005823.1 hypothetical protein 4188873 2772780 LIC13414 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003317.1 4187830 R 267671 CDS YP_003318.1 45659232 2771274 complement(4189213..4190844) 1 NC_005823.1 AraC family transcriptional regulator 4190844 2771274 LIC13415 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 AraC family transcriptional regulator YP_003318.1 4189213 R 267671 CDS YP_003319.1 45659233 2770646 4191341..4192309 1 NC_005823.1 hypothetical protein 4192309 2770646 LIC13416 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003319.1 4191341 D 267671 CDS YP_003320.1 45659234 2771433 4192664..4193515 1 NC_005823.1 hypothetical protein 4193515 2771433 LIC13417 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003320.1 4192664 D 267671 CDS YP_003321.1 45659235 2770360 4193591..4194616 1 NC_005823.1 hypothetical protein 4194616 2770360 LIC13418 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003321.1 4193591 D 267671 CDS YP_003322.1 45659236 2770351 4194635..4196356 1 NC_005823.1 hydrogenase subunit 4196356 hycC 2770351 hycC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hydrogenase subunit YP_003322.1 4194635 D 267671 CDS YP_003323.1 45659237 2771218 4196323..4197210 1 NC_005823.1 hydrogenase subunit 4197210 hycD 2771218 hycD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hydrogenase subunit YP_003323.1 4196323 D 267671 CDS YP_003324.1 45659238 2771188 4197229..4197849 1 NC_005823.1 hypothetical protein 4197849 2771188 LIC13421 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003324.1 4197229 D 267671 CDS YP_003325.1 45659239 2771619 4197846..4199054 1 NC_005823.1 hydrogenase subunit 4199054 2771619 LIC13422 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hydrogenase subunit YP_003325.1 4197846 D 267671 CDS YP_003326.1 45659240 2772091 4199055..4200455 1 NC_005823.1 hydrogenase subunit 4200455 hycE 2772091 hycE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hydrogenase subunit YP_003326.1 4199055 D 267671 CDS YP_003327.1 45659241 2772653 4200452..4201273 1 NC_005823.1 hydrogenase subunit 4201273 hycG 2772653 hycG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hydrogenase subunit YP_003327.1 4200452 D 267671 CDS YP_003328.1 45659242 2771643 4201451..4202239 1 NC_005823.1 hypothetical protein 4202239 2771643 LIC13425 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003328.1 4201451 D 267671 CDS YP_003329.1 45659243 2770570 4202236..4202781 1 NC_005823.1 hypothetical protein 4202781 2770570 LIC13426 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003329.1 4202236 D 267671 CDS YP_003330.1 45659244 2771805 complement(4202746..4203153) 1 NC_005823.1 response regulator 4203153 2771805 LIC13427 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_003330.1 4202746 R 267671 CDS YP_003331.1 45659245 2772212 complement(4203265..4204680) 1 NC_005823.1 hypothetical protein 4204680 2772212 LIC13428 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003331.1 4203265 R 267671 CDS YP_003332.1 45659246 2772048 complement(4205723..4206652) 1 NC_005823.1 hypothetical protein 4206652 2772048 LIC13429 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003332.1 4205723 R 267671 CDS YP_003333.1 45659247 2772709 4206766..4207656 1 NC_005823.1 hypothetical protein 4207656 2772709 LIC13430 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003333.1 4206766 D 267671 CDS YP_003334.1 45659248 2772308 4207964..4208911 1 NC_005823.1 ABC transporter ATP-binding protein 4208911 pab1703 2772308 pab1703 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ABC transporter ATP-binding protein YP_003334.1 4207964 D 267671 CDS YP_003335.1 45659249 2772512 4208908..4209990 1 NC_005823.1 hypothetical protein 4209990 2772512 LIC13432 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003335.1 4208908 D 267671 CDS YP_003336.1 45659250 2772385 4209987..4211135 1 NC_005823.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 4211135 pyrD 2772385 pyrD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dihydroorotate dehydrogenase 2 YP_003336.1 4209987 D 267671 CDS YP_003337.1 45659251 2771266 4211239..4212681 1 NC_005823.1 hypothetical protein 4212681 2771266 LIC13434 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003337.1 4211239 D 267671 CDS YP_003338.1 45659252 2771845 4212704..4213276 1 NC_005823.1 hypothetical protein 4213276 2771845 LIC13435 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003338.1 4212704 D 267671 CDS YP_003339.1 45659253 2771995 complement(4213755..4214429) 1 NC_005823.1 hypothetical protein 4214429 2771995 LIC13436 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003339.1 4213755 R 267671 CDS YP_003340.1 45659254 2771792 4214459..4215019 1 NC_005823.1 hypothetical protein 4215019 2771792 LIC13437 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003340.1 4214459 D 267671 CDS YP_003341.1 45659255 2771042 4215019..4215570 1 NC_005823.1 hypoxanthine-guanine-xanthine phosphoribosyltransferase 4215570 hpt 2771042 hpt Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypoxanthine-guanine-xanthine phosphoribosyltransferase YP_003341.1 4215019 D 267671 CDS YP_003342.1 45659256 2772662 4215862..4217634 1 NC_005823.1 potassium efflux transporter 4217634 pa5518 2772662 pa5518 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 potassium efflux transporter YP_003342.1 4215862 D 267671 CDS YP_003343.1 45659257 2771654 4217640..4217825 1 NC_005823.1 hypothetical protein 4217825 2771654 LIC13440 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003343.1 4217640 D 267671 CDS YP_003344.1 45659258 2769836 complement(4218355..4218801) 1 NC_005823.1 MarR family transcriptional regulator 4218801 2769836 LIC13441 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 MarR family transcriptional regulator YP_003344.1 4218355 R 267671 CDS YP_003345.1 45659259 2772678 complement(4218825..4219322) 1 NC_005823.1 glutathione peroxidase 4219322 gpo 2772678 gpo Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutathione peroxidase YP_003345.1 4218825 R 267671 CDS YP_003346.1 45659260 2771793 4219974..4220738 1 NC_005823.1 hypothetical protein 4220738 2771793 LIC13443 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003346.1 4219974 D 267671 CDS YP_003347.1 45659261 2772829 4220749..4222545 1 NC_005823.1 glutathione-regulated potassium-efflux system protein 4222545 vc2606 2772829 vc2606 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutathione-regulated potassium-efflux system protein YP_003347.1 4220749 D 267671 CDS YP_003348.1 45659262 2772689 4222702..4222905 1 NC_005823.1 hypothetical protein 4222905 2772689 LIC13445 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003348.1 4222702 D 267671 CDS YP_003349.1 45659263 2772680 4223540..4224046 1 NC_005823.1 hypothetical protein 4224046 2772680 LIC13446 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003349.1 4223540 D 267671 CDS YP_003350.1 45659264 2771962 complement(4224336..4225145) 1 NC_005823.1 lipoprotein 4225145 2771962 LIC13447 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003350.1 4224336 R 267671 CDS YP_003351.1 45659265 2771943 complement(4225364..4225618) 1 NC_005823.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 4225618 csrA 2771943 csrA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 carbon storage regulator YP_003351.1 4225364 R 267671 CDS YP_003352.1 45659266 2770336 complement(4225618..4226070) 1 NC_005823.1 binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 4226070 2770336 LIC13449 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar assembly protein FliW YP_003352.1 4225618 R 267671 CDS YP_003353.1 45659267 2772229 complement(4226112..4227380) 1 NC_005823.1 With FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgL 4227380 flgL 2772229 flgL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar hook-associated protein FlgL YP_003353.1 4226112 R 267671 CDS YP_003354.1 45659268 2772356 complement(4227417..4229327) 1 NC_005823.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 4229327 flgK 2772356 flgK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 flagellar hook-associated protein FlgK YP_003354.1 4227417 R 267671 CDS YP_003355.1 45659269 2772378 complement(4229360..4229887) 1 NC_005823.1 hypothetical protein 4229887 2772378 LIC13452 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003355.1 4229360 R 267671 CDS YP_003356.1 45659270 2770773 4231045..4232151 1 NC_005823.1 hypothetical protein 4232151 2770773 LIC13453 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003356.1 4231045 D 267671 CDS YP_003357.1 45659271 2772521 complement(4232730..4233032) 1 NC_005823.1 hypothetical protein 4233032 2772521 LIC13454 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003357.1 4232730 R 267671 CDS YP_003358.1 45659272 2769856 complement(4233256..4233609) 1 NC_005823.1 hypothetical protein 4233609 2769856 LIC13455 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003358.1 4233256 R 267671 CDS YP_003359.1 45659273 2772292 complement(4233823..4234818) 1 NC_005823.1 hypothetical protein 4234818 2772292 LIC13456 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003359.1 4233823 R 267671 CDS YP_003360.1 45659274 2772518 4234880..4235515 1 NC_005823.1 hypothetical protein 4235515 2772518 LIC13457 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003360.1 4234880 D 267671 CDS YP_003361.1 45659275 2772761 4235627..4235818 1 NC_005823.1 hypothetical protein 4235818 2772761 LIC13458 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003361.1 4235627 D 267671 CDS YP_003362.1 45659276 2771869 complement(4236084..4236416) 1 NC_005823.1 hypothetical protein 4236416 2771869 LIC13459 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003362.1 4236084 R 267671 CDS YP_003363.1 45659277 2771757 4236751..4237125 1 NC_005823.1 lipoprotein 4237125 2771757 LIC13460 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003363.1 4236751 D 267671 CDS YP_003364.1 45659278 2772418 4237134..4237721 1 NC_005823.1 lipoprotein 4237721 2772418 LIC13461 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003364.1 4237134 D 267671 CDS YP_003365.1 45659279 2770583 4237740..4238126 1 NC_005823.1 hypothetical protein 4238126 2770583 LIC13462 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003365.1 4237740 D 267671 CDS YP_003366.1 45659280 2770260 complement(4238123..4238473) 1 NC_005823.1 hypothetical protein 4238473 2770260 LIC13463 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003366.1 4238123 R 267671 CDS YP_003367.1 45659281 2772307 complement(4238454..4240049) 1 NC_005823.1 carboxypeptidase I 4240049 2772307 LIC13464 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 carboxypeptidase I YP_003367.1 4238454 R 267671 CDS YP_003368.1 45659282 2772501 complement(4240294..4240503) 1 NC_005823.1 hypothetical protein 4240503 2772501 LIC13466 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003368.1 4240294 R 267671 CDS YP_003369.1 45659283 2772442 4242196..4243614 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 4243614 2772442 LIC13467 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003369.1 4242196 D 267671 CDS YP_003370.1 45659284 2772344 complement(4243697..4243894) 1 NC_005823.1 hypothetical protein 4243894 2772344 LIC13468 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003370.1 4243697 R 267671 CDS YP_003371.1 45659285 2771742 complement(4243955..4245070) 1 NC_005823.1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 4245070 lpxD 2771742 lpxD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_003371.1 4243955 R 267671 CDS YP_003372.1 45659286 2771275 4245217..4246161 1 NC_005823.1 ferredoxin--NADP reductase 4246161 2771275 LIC13470 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ferredoxin--NADP reductase YP_003372.1 4245217 D 267671 CDS YP_003373.1 45659287 2771185 4246767..4246982 1 NC_005823.1 transcriptional coactivator 4246982 2771185 LIC13471 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 transcriptional coactivator YP_003373.1 4246767 D 267671 CDS YP_003374.1 45659288 2771409 4247499..4248104 1 NC_005823.1 cytidine deaminase 4248104 cdd 2771409 cdd Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytidine deaminase YP_003374.1 4247499 D 267671 CDS YP_003375.1 45659289 2771309 4248234..4249673 1 NC_005823.1 DNA polymerase III subunit gamma 4249673 dnaX 2771309 dnaX Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA polymerase III subunit gamma YP_003375.1 4248234 D 267671 CDS YP_003376.1 45659290 2772220 4249678..4250025 1 NC_005823.1 hypothetical protein 4250025 2772220 LIC13475 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003376.1 4249678 D 267671 CDS YP_003377.1 45659291 2771075 4250006..4250611 1 NC_005823.1 recombination protein; involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 4250611 recR 2771075 recR Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 recombination protein RecR YP_003377.1 4250006 D 267671 CDS YP_003378.1 45659292 2771137 complement(4251001..4252575) 1 NC_005823.1 hypothetical protein 4252575 2771137 LIC13477 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003378.1 4251001 R 267671 CDS YP_003379.1 45659293 2771694 complement(4252579..4253427) 1 NC_005823.1 cystine-binding periplasmic protein precursor 4253427 2771694 LIC13478 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cystine-binding periplasmic protein precursor YP_003379.1 4252579 R 267671 CDS YP_003380.1 45659294 2771175 complement(4253491..4254777) 1 NC_005823.1 OmpA-like; identified by sequence similarity; ORF located using Blastx/Glimmer; hypothetical protein 4254777 2771175 LIC13479 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003380.1 4253491 R 267671 CDS YP_003381.1 45659295 2770491 complement(4255880..4257133) 1 NC_005823.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 4257133 serS 2770491 serS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 seryl-tRNA synthetase YP_003381.1 4255880 R 267671 CDS YP_003382.1 45659296 2770993 complement(4257126..4257935) 1 NC_005823.1 hypothetical protein 4257935 2770993 LIC13481 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003382.1 4257126 R 267671 CDS YP_003383.1 45659297 2770097 4258056..4259075 1 NC_005823.1 hypothetical protein 4259075 2770097 LIC13482 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003383.1 4258056 D 267671 CDS YP_003384.1 45659298 2770362 4259075..4259422 1 NC_005823.1 hypothetical protein 4259422 2770362 LIC13483 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003384.1 4259075 D 267671 CDS YP_003385.1 45659299 2771584 4259419..4259916 1 NC_005823.1 hypothetical protein 4259916 2771584 LIC13484 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003385.1 4259419 D 267671 CDS YP_003386.1 45659300 2772278 complement(4262110..4262922) 1 NC_005823.1 hypothetical protein 4262922 2772278 LIC13487 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003386.1 4262110 R 267671 CDS YP_003387.1 45659301 2772258 complement(4262984..4263859) 1 NC_005823.1 hypothetical protein 4263859 parB 2772258 parB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003387.1 4262984 R 267671 CDS YP_003388.1 45659302 2771863 complement(4263862..4264623) 1 NC_005823.1 hypothetical protein 4264623 parA 2771863 parA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003388.1 4263862 R 267671 CDS YP_003389.1 45659303 2771618 complement(4264601..4265365) 1 NC_005823.1 glucose inhibited division protein B 4265365 gidB 2771618 gidB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glucose inhibited division protein B YP_003389.1 4264601 R 267671 CDS YP_003390.1 45659304 2770710 complement(4266394..4267842) 1 NC_005823.1 metallopeptidase 4267842 2770710 LIC13491 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 metallopeptidase YP_003390.1 4266394 R 267671 CDS YP_003391.1 45659305 2772288 4270542..4271372 1 NC_005823.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 4271372 2772288 LIC13494 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003391.1 4270542 D 267671 CDS YP_003392.1 45659306 2771617 complement(4273100..4275007) 1 NC_005823.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 4275007 gidA 2771617 gidA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_003392.1 4273100 R 267671 CDS YP_003393.1 45659307 2770631 4275118..4276074 1 NC_005823.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4276074 ilvE 2770631 ilvE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 branched-chain amino acid aminotransferase YP_003393.1 4275118 D 267671 CDS YP_003394.1 45659308 2769996 4276081..4277013 1 NC_005823.1 DNA polymerase III subunit-like protein 4277013 2769996 LIC13497 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA polymerase III subunit-like protein YP_003394.1 4276081 D 267671 CDS YP_003395.1 45655586 2769429 15..2531 1 NC_005824.1 hypothetical protein 2531 2769429 LIC20001 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003395.1 15 D 267671 CDS YP_003396.1 45655587 2769440 2491..3423 1 NC_005824.1 5,10 methylene tetrahydrofolate reductase 3423 metF 2769440 metF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 5,10 methylene tetrahydrofolate reductase YP_003396.1 2491 D 267671 CDS YP_003397.1 45655588 2769345 complement(4064..4888) 1 NC_005824.1 hypothetical protein 4888 2769345 LIC20005 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003397.1 4064 R 267671 CDS YP_003398.1 45655589 2769433 5214..6086 1 NC_005824.1 haloacid dehalogenase-like protein 6086 cof 2769433 cof Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 haloacid dehalogenase-like protein YP_003398.1 5214 D 267671 CDS YP_003399.1 45655590 2769411 complement(6057..6347) 1 NC_005824.1 hypothetical protein 6347 2769411 LIC20007 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003399.1 6057 R 267671 CDS YP_003400.1 45655591 2769374 6384..7253 1 NC_005824.1 glutamyl-tRNA reductase 7253 hemA 2769374 hemA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutamyl-tRNA reductase YP_003400.1 6384 D 267671 CDS YP_003401.1 45655592 2769427 7223..8866 1 NC_005824.1 porphobilinogen deaminase 8866 hemC 2769427 hemC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 porphobilinogen deaminase YP_003401.1 7223 D 267671 CDS YP_003402.1 45655593 2769410 8835..9788 1 NC_005824.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 9788 hemB 2769410 hemB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 delta-aminolevulinic acid dehydratase YP_003402.1 8835 D 267671 CDS YP_003403.1 45655594 2769462 9785..11116 1 NC_005824.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 11116 hemL 2769462 hemL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutamate-1-semialdehyde aminotransferase YP_003403.1 9785 D 267671 CDS YP_003404.1 45655595 2769386 11116..12033 1 NC_005824.1 histidine kinase sensor protein 12033 2769386 LIC20012 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_003404.1 11116 D 267671 CDS YP_003405.1 45655596 2769355 12030..12722 1 NC_005824.1 response regulator 12722 2769355 LIC20013 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_003405.1 12030 D 267671 CDS YP_003406.1 45655597 2769236 12712..13734 1 NC_005824.1 uroporphyrinogen decarboxylase 13734 hemE 2769236 hemE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 uroporphyrinogen decarboxylase YP_003406.1 12712 D 267671 CDS YP_003407.1 45655598 2769454 13749..15080 1 NC_005824.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 15080 hemN 2769454 hemN Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 coproporphyrinogen III oxidase YP_003407.1 13749 D 267671 CDS YP_003408.1 45655599 2769356 15160..16143 1 NC_005824.1 hypothetical protein 16143 2769356 LIC20016 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003408.1 15160 D 267671 CDS YP_003409.1 45655600 2769270 16251..17534 1 NC_005824.1 protoporphyrinogen oxidase 17534 hemG 2769270 hemG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 protoporphyrinogen oxidase YP_003409.1 16251 D 267671 CDS YP_003410.1 45655601 2769263 complement(18373..19281) 1 NC_005824.1 ferrochelatase 19281 hemH 2769263 hemH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ferrochelatase YP_003410.1 18373 R 267671 CDS YP_003411.1 45655602 2769213 complement(19541..20680) 1 NC_005824.1 hypothetical protein 20680 2769213 LIC20019 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003411.1 19541 R 267671 CDS YP_003412.1 45655603 2769449 20842..21759 1 NC_005824.1 chromosome partitioning; identified by sequence similarity; putative; ORF located using Blastx/Glimmer; hypothetical protein 21759 2769449 LIC20020 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003412.1 20842 D 267671 CDS YP_003413.1 45655604 2769239 21752..22459 1 NC_005824.1 chromosome partitioning; identified by sequence similarity; putative; ORF located using Blastx/Glimmer; hypothetical protein 22459 2769239 LIC20021 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003413.1 21752 D 267671 CDS YP_003414.1 45655605 2769405 22559..23161 1 NC_005824.1 azoreductase 23161 2769405 LIC20022 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 azoreductase YP_003414.1 22559 D 267671 CDS YP_003415.1 45655606 2769342 complement(23764..24927) 1 NC_005824.1 intercellular adhesion protein C 24927 2769342 LIC20023 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 intercellular adhesion protein C YP_003415.1 23764 R 267671 CDS YP_003417.1 45655608 2769354 25023..25382 1 NC_005824.1 cyclic nucleotide binding protein 25382 2769354 LIC20025 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cyclic nucleotide binding protein YP_003417.1 25023 D 267671 CDS YP_003418.1 45655609 2769243 25778..26533 1 NC_005824.1 short-chain dehydrogenase 26533 2769243 LIC20026 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 short-chain dehydrogenase YP_003418.1 25778 D 267671 CDS YP_003419.1 45655610 2769262 26509..27060 1 NC_005824.1 phosphotyrosine protein phosphatase 27060 wzb 2769262 wzb Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphotyrosine protein phosphatase YP_003419.1 26509 D 267671 CDS YP_003420.1 45655611 2769318 27090..28358 1 NC_005824.1 NADH dehydrogenase 28358 ndh 2769318 ndh Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 NADH dehydrogenase YP_003420.1 27090 D 267671 CDS YP_003421.1 45655612 2769471 28376..28813 1 NC_005824.1 hypothetical protein 28813 2769471 LIC20029 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003421.1 28376 D 267671 CDS YP_003422.1 45655613 2769248 complement(29256..29864) 1 NC_005824.1 hypothetical protein 29864 2769248 LIC20030 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003422.1 29256 R 267671 CDS YP_003423.1 45655614 2769216 30234..31058 1 NC_005824.1 short-chain dehydrogenase 31058 2769216 LIC20031 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 short-chain dehydrogenase YP_003423.1 30234 D 267671 CDS YP_003424.1 45655615 2769290 31068..31490 1 NC_005824.1 hypothetical protein 31490 2769290 LIC20032 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003424.1 31068 D 267671 CDS YP_003425.1 45655616 2769238 31552..31923 1 NC_005824.1 hypothetical protein 31923 2769238 LIC20033 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003425.1 31552 D 267671 CDS YP_003426.1 45655617 2769381 32250..33320 1 NC_005824.1 hypothetical protein 33320 2769381 LIC20034 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003426.1 32250 D 267671 CDS YP_003427.1 45655618 2769419 34573..35895 1 NC_005824.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 35895 2769419 LIC20035 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003427.1 34573 D 267671 CDS YP_003428.1 45655619 2769380 37317..37931 1 NC_005824.1 hypothetical protein 37931 2769380 LIC20036 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003428.1 37317 D 267671 CDS YP_003429.1 45655620 2769398 37992..39065 1 NC_005824.1 methanol dehydrogenase regulator 39065 moxR 2769398 moxR Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methanol dehydrogenase regulator YP_003429.1 37992 D 267671 CDS YP_003430.1 45655621 2769242 39072..39902 1 NC_005824.1 hypothetical protein 39902 2769242 LIC20038 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003430.1 39072 D 267671 CDS YP_003431.1 45655622 2769249 39899..40768 1 NC_005824.1 hypothetical protein 40768 2769249 LIC20039 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003431.1 39899 D 267671 CDS YP_003432.1 45655623 2769384 40741..41703 1 NC_005824.1 BatA 41703 batA 2769384 batA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 BatA YP_003432.1 40741 D 267671 CDS YP_003433.1 45655624 2769233 41700..42743 1 NC_005824.1 BatB 42743 batB 2769233 batB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 BatB YP_003433.1 41700 D 267671 CDS YP_003434.1 45655625 2769344 42740..43429 1 NC_005824.1 BatC 43429 batC 2769344 batC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 BatC YP_003434.1 42740 D 267671 CDS YP_003435.1 45655626 2769269 43426..45069 1 NC_005824.1 BatD 45069 batD 2769269 batD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 BatD YP_003435.1 43426 D 267671 CDS YP_003436.1 45655627 2769258 45066..46889 1 NC_005824.1 molecular chaperone; heat shock protein 90 46889 htpG 2769258 htpG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heat shock protein 90 YP_003436.1 45066 D 267671 CDS YP_003437.1 45655628 2769452 46907..47476 1 NC_005824.1 hypothetical protein 47476 2769452 LIC20045 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003437.1 46907 D 267671 CDS YP_003438.1 45655629 2769312 complement(47457..47948) 1 NC_005824.1 hypothetical protein 47948 2769312 LIC20046 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003438.1 47457 R 267671 CDS YP_003439.1 45655630 2769218 48178..49776 1 NC_005824.1 hypothetical protein 49776 2769218 LIC20047 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003439.1 48178 D 267671 CDS YP_003440.1 45655631 2769361 complement(49784..50128) 1 NC_005824.1 anti-sigma factor antagonist 50128 2769361 LIC20048 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_003440.1 49784 R 267671 CDS YP_003441.1 45655632 2769350 complement(50125..51144) 1 NC_005824.1 hypothetical protein 51144 2769350 LIC20049 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003441.1 50125 R 267671 CDS YP_003442.1 45655633 2769392 51217..52137 1 NC_005824.1 hypothetical protein 52137 2769392 LIC20050 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003442.1 51217 D 267671 CDS YP_003443.1 45655634 2769463 52134..52613 1 NC_005824.1 hypothetical protein 52613 2769463 LIC20051 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003443.1 52134 D 267671 CDS YP_003444.1 45655635 2769407 52991..53812 1 NC_005824.1 fatty acid desaturase 53812 scd 2769407 scd Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 fatty acid desaturase YP_003444.1 52991 D 267671 CDS YP_003445.1 45655636 2769200 55114..55788 1 NC_005824.1 hypothetical protein 55788 2769200 LIC20053 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003445.1 55114 D 267671 CDS YP_003446.1 45655637 2769340 57065..57715 1 NC_005824.1 hypothetical protein 57715 2769340 LIC20054 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003446.1 57065 D 267671 CDS YP_003447.1 45655638 2769406 complement(58042..58917) 1 NC_005824.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 58917 2769406 LIC20055 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003447.1 58042 R 267671 CDS YP_003448.1 45655639 2769439 59235..59771 1 NC_005824.1 hypothetical protein 59771 2769439 LIC20056 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003448.1 59235 D 267671 CDS YP_003449.1 45655640 2769382 complement(59901..60869) 1 NC_005824.1 LAO/AO transport system kinase 60869 argK 2769382 argK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 LAO/AO transport system kinase YP_003449.1 59901 R 267671 CDS YP_003450.1 45655641 2769444 complement(60877..62889) 1 NC_005824.1 methylmalonyl-CoA mutase 62889 mcm2 2769444 mcm2 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methylmalonyl-CoA mutase YP_003450.1 60877 R 267671 CDS YP_003451.1 45655642 2769230 62996..64333 1 NC_005824.1 hypothetical protein 64333 2769230 LIC20059 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003451.1 62996 D 267671 CDS YP_003452.1 45655643 2769376 65464..66156 1 NC_005824.1 hypothetical protein 66156 2769376 LIC20060 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003452.1 65464 D 267671 CDS YP_003453.1 45655644 2769333 complement(66779..67852) 1 NC_005824.1 thiol-disulfide interchange like protein 67852 2769333 LIC20061 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 thiol-disulfide interchange like protein YP_003453.1 66779 R 267671 CDS YP_003454.1 45655645 2769460 67981..68259 1 NC_005824.1 phosphoribosyl-ATP pyrophosphatase 68259 hisE 2769460 hisE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoribosyl-ATP pyrophosphatase YP_003454.1 67981 D 267671 CDS YP_003455.1 45655646 2769456 68263..70194 1 NC_005824.1 hypothetical protein 70194 2769456 LIC20063 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003455.1 68263 D 267671 CDS YP_003456.1 45655647 2769227 70663..71427 1 NC_005824.1 3-oxoacyl-(acyl-carrier protein) reductase 71427 fabG 2769227 fabG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-oxoacyl-(acyl-carrier protein) reductase YP_003456.1 70663 D 267671 CDS YP_003457.1 45655648 2769226 71920..72153 1 NC_005824.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 72153 acpP 2769226 acpP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acyl carrier protein YP_003457.1 71920 D 267671 CDS YP_003458.1 45655649 2769357 72207..72950 1 NC_005824.1 dsRNase III 72950 rnC 2769357 rnC Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dsRNase III YP_003458.1 72207 D 267671 CDS YP_003459.1 45655650 2769425 73327..73914 1 NC_005824.1 MutT-like protein 73914 2769425 LIC20067 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 MutT-like protein YP_003459.1 73327 D 267671 CDS YP_003460.1 45655651 2769459 73911..74996 1 NC_005824.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 74996 aroB 2769459 aroB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-dehydroquinate synthase YP_003460.1 73911 D 267671 CDS YP_003461.1 45655652 2769201 74996..75877 1 NC_005824.1 small conductance mechanosensitive ion channel 75877 2769201 LIC20069 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 small conductance mechanosensitive ion channel YP_003461.1 74996 D 267671 CDS YP_003462.1 45655653 2769264 76088..76579 1 NC_005824.1 hypothetical protein 76579 2769264 LIC20070 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003462.1 76088 D 267671 CDS YP_003463.1 45655654 2769205 77095..78651 1 NC_005824.1 putative FAD-dependent dehydrogenase 78651 2769205 LIC20071 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 putative FAD-dependent dehydrogenase YP_003463.1 77095 D 267671 CDS YP_003464.1 45655655 2769208 78701..79240 1 NC_005824.1 hypothetical protein 79240 2769208 LIC20072 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003464.1 78701 D 267671 CDS YP_003858667.1 304570517 9714937 complement(79548..79757) 1 NC_005824.1 hypothetical protein 79757 9714937 LIC20302 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003858667.1 79548 R 267671 CDS YP_003465.1 45655656 2769207 complement(79841..80251) 1 NC_005824.1 hypothetical protein 80251 2769207 LIC20073 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003465.1 79841 R 267671 CDS YP_003466.1 45655657 2769215 complement(80308..82245) 1 NC_005824.1 long-chain-fatty-acid--CoA ligase 82245 2769215 LIC20074 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 long-chain-fatty-acid--CoA ligase YP_003466.1 80308 R 267671 CDS YP_003467.1 45655658 2769210 82407..85346 1 NC_005824.1 adenylate/guanylate cyclase 85346 2769210 LIC20075 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_003467.1 82407 D 267671 CDS YP_003468.1 45655659 2769423 complement(85904..86656) 1 NC_005824.1 putative S-adenosyl methionine dependent methyltransferase like protein 86656 2769423 LIC20076 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 putative S-adenosyl methionine dependent methyltransferase like protein YP_003468.1 85904 R 267671 CDS YP_003469.1 45655660 2769441 complement(86696..88126) 1 NC_005824.1 polysaccharide deacetylase 88126 2769441 LIC20077 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 polysaccharide deacetylase YP_003469.1 86696 R 267671 CDS YP_003470.1 45655661 2769330 complement(88319..88834) 1 NC_005824.1 hypothetical protein 88834 2769330 LIC20078 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003470.1 88319 R 267671 CDS YP_003471.1 45655662 2769232 89587..90396 1 NC_005824.1 haloacid dehalogenase-like protein 90396 nagD 2769232 nagD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 haloacid dehalogenase-like protein YP_003471.1 89587 D 267671 CDS YP_003472.1 45655663 2769362 complement(90403..90831) 1 NC_005824.1 4-hydroxybenzoyl-CoA thioesterase 90831 2769362 LIC20080 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 4-hydroxybenzoyl-CoA thioesterase YP_003472.1 90403 R 267671 CDS YP_003473.1 45655664 2769390 complement(91097..91675) 1 NC_005824.1 TetR family transcriptional regulator 91675 2769390 LIC20081 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 TetR family transcriptional regulator YP_003473.1 91097 R 267671 CDS YP_003474.1 45655665 2769438 92473..93489 1 NC_005824.1 ArsR family transcriptional regulator 93489 2769438 LIC20082 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ArsR family transcriptional regulator YP_003474.1 92473 D 267671 CDS YP_003475.1 45655666 2769296 93491..94801 1 NC_005824.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 94801 ahcY 2769296 ahcY Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 S-adenosyl-L-homocysteine hydrolase YP_003475.1 93491 D 267671 CDS YP_003476.1 45655667 2769206 94874..95173 1 NC_005824.1 ferredoxin 95173 2769206 LIC20084 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ferredoxin YP_003476.1 94874 D 267671 CDS YP_003477.1 45655668 2769436 95220..98963 1 NC_005824.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 98963 metH 2769436 metH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 B12-dependent methionine synthase YP_003477.1 95220 D 267671 CDS YP_003478.1 45655669 2769328 99071..99409 1 NC_005824.1 hypothetical protein 99409 2769328 LIC20086 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003478.1 99071 D 267671 CDS YP_003479.1 45655670 2769289 complement(99745..100677) 1 NC_005824.1 outer membrane protein 100677 2769289 LIC20087 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 outer membrane protein YP_003479.1 99745 R 267671 CDS YP_003480.1 45655671 2769241 100789..102084 1 NC_005824.1 catalyzes the formation of fructose 1,6-bisphosphate from fructose 6-phosphate and diphosphate; diphosphate--fructose-6-phosphate 1-phosphotransferase 102084 pfp 2769241 pfp Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 diphosphate--fructose-6-phosphate 1-phosphotransferase YP_003480.1 100789 D 267671 CDS YP_003481.1 45655672 2769378 complement(102283..104028) 1 NC_005824.1 sigma factor regulatory protein 104028 2769378 LIC20089 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sigma factor regulatory protein YP_003481.1 102283 R 267671 CDS YP_003482.1 45655673 2769421 complement(104206..105090) 1 NC_005824.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 105090 argB 2769421 argB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acetylglutamate kinase YP_003482.1 104206 R 267671 CDS YP_003483.1 45655674 2769274 105080..105898 1 NC_005824.1 short-chain dehydrogenase 105898 2769274 LIC20091 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 short-chain dehydrogenase YP_003483.1 105080 D 267671 CDS YP_003484.1 45655675 2769420 complement(106836..108578) 1 NC_005824.1 hypothetical protein 108578 2769420 LIC20092 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003484.1 106836 R 267671 CDS YP_003485.1 45655676 2769228 complement(108571..109062) 1 NC_005824.1 bacterioferritin comigratory protein 109062 bcp 2769228 bcp Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 bacterioferritin comigratory protein YP_003485.1 108571 R 267671 CDS YP_003486.1 45655677 2769301 109614..111380 1 NC_005824.1 adenylate/guanylate cyclase 111380 2769301 LIC20094 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenylate/guanylate cyclase YP_003486.1 109614 D 267671 CDS YP_003487.1 45655678 2769323 112543..112911 1 NC_005824.1 hypothetical protein 112911 2769323 LIC20095 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003487.1 112543 D 267671 CDS YP_003488.1 45655679 2769283 112958..114055 1 NC_005824.1 hypothetical protein 114055 2769283 LIC20096 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003488.1 112958 D 267671 CDS YP_003489.1 45655680 2769309 114072..114884 1 NC_005824.1 short-chain dehydrogenase 114884 2769309 LIC20097 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 short-chain dehydrogenase YP_003489.1 114072 D 267671 CDS YP_003490.1 45655681 2769320 complement(114933..115832) 1 NC_005824.1 phage-related integrase/recombinase 115832 2769320 LIC20098 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phage-related integrase/recombinase YP_003490.1 114933 R 267671 CDS YP_003491.1 45655682 2769316 complement(115948..116487) 1 NC_005824.1 shikimate kinase 116487 aroK 2769316 aroK Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 shikimate kinase YP_003491.1 115948 R 267671 CDS YP_003492.1 45655683 2769467 complement(116484..117335) 1 NC_005824.1 hypothetical protein 117335 2769467 LIC20100 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003492.1 116484 R 267671 CDS YP_003493.1 45655684 2769366 complement(117341..117892) 1 NC_005824.1 hypothetical protein 117892 cheD 2769366 cheD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003493.1 117341 R 267671 CDS YP_003494.1 45655685 2769417 118019..119245 1 NC_005824.1 pheromone shutdown protein 119245 traB 2769417 traB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pheromone shutdown protein YP_003494.1 118019 D 267671 CDS YP_003495.1 45655686 2769396 119569..120132 1 NC_005824.1 hypothetical protein 120132 2769396 LIC20103 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003495.1 119569 D 267671 CDS YP_003496.1 45655687 2769331 complement(121327..122511) 1 NC_005824.1 DNA binding protein 122511 2769331 LIC20104 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA binding protein YP_003496.1 121327 R 267671 CDS YP_003497.1 45655688 2769346 complement(122757..123866) 1 NC_005824.1 DNA binding protein 123866 2769346 LIC20105 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA binding protein YP_003497.1 122757 R 267671 CDS YP_003498.1 45655689 2769336 125109..126713 1 NC_005824.1 EAL domain; identified by sequence similarity; putative; ORF located using Blastx/Glimmer; putative diguanylate phosphodiesterase 126713 2769336 LIC20106 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 putative diguanylate phosphodiesterase YP_003498.1 125109 D 267671 CDS YP_003499.1 45655690 2769278 127559..128008 1 NC_005824.1 hypothetical protein 128008 2769278 LIC20107 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003499.1 127559 D 267671 CDS YP_003500.1 45655691 2769254 complement(128943..129341) 1 NC_005824.1 anti-sigma factor antagonist 129341 2769254 LIC20108 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 anti-sigma factor antagonist YP_003500.1 128943 R 267671 CDS YP_003501.1 45655692 2769219 complement(129352..130350) 1 NC_005824.1 hypothetical protein 130350 2769219 LIC20109 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003501.1 129352 R 267671 CDS YP_003502.1 45655693 2769391 complement(130347..131804) 1 NC_005824.1 internal repeat sequences detected; contains TPR domain as detected by pfam-hmmr; hypothetical protein 131804 2769391 LIC20110 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003502.1 130347 R 267671 CDS YP_003503.1 45655694 2769250 complement(131807..133300) 1 NC_005824.1 sigma factor regulatory protein 133300 2769250 LIC20111 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sigma factor regulatory protein YP_003503.1 131807 R 267671 CDS YP_003504.1 45655695 2769359 complement(134914..135621) 1 NC_005824.1 periplasmic protein, LipL45 homologue 135621 2769359 LIC20112 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 periplasmic protein, LipL45 homologue YP_003504.1 134914 R 267671 CDS YP_003505.1 45655696 2769202 complement(135874..136425) 1 NC_005824.1 hypothetical protein 136425 2769202 LIC20113 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003505.1 135874 R 267671 CDS YP_003506.1 45655697 2769437 complement(136489..137580) 1 NC_005824.1 LipL45 homologue 137580 2769437 LIC20114 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 LipL45 homologue YP_003506.1 136489 R 267671 CDS YP_003507.1 45655698 2769257 complement(137601..138122) 1 NC_005824.1 RNA polymerase ECF-type sigma factor 138122 2769257 LIC20115 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 RNA polymerase ECF-type sigma factor YP_003507.1 137601 R 267671 CDS YP_003508.1 45655699 2769337 140003..140650 1 NC_005824.1 hypothetical protein 140650 2769337 LIC20117 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003508.1 140003 D 267671 CDS YP_003509.1 45655700 2769347 complement(141160..141501) 1 NC_005824.1 hypothetical protein 141501 2769347 LIC20118 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003509.1 141160 R 267671 CDS YP_003510.1 45655701 2769288 complement(142054..142677) 1 NC_005824.1 PMG1; phosphoglycerate mutase 142677 pgmA 2769288 pgmA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphoglycerate mutase YP_003510.1 142054 R 267671 CDS YP_003511.1 45655702 2769442 complement(142694..143641) 1 NC_005824.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; cobalamin biosynthesis protein 143641 cobD 2769442 cobD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cobalamin biosynthesis protein YP_003511.1 142694 R 267671 CDS YP_003512.1 45655703 2769446 complement(143645..146236) 1 NC_005824.1 histidinol-phosphate aminotransferase and cobyric acid synthase 146236 cbiP 2769446 cbiP Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidinol-phosphate aminotransferase and cobyric acid synthase YP_003512.1 143645 R 267671 CDS YP_003513.1 45655704 2769341 complement(146236..146820) 1 NC_005824.1 phosphate guanyltransferase; cobinamide kinase 146820 cobU 2769341 cobU Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cobinamide kinase YP_003513.1 146236 R 267671 CDS YP_003514.1 45655705 2769412 complement(146796..147479) 1 NC_005824.1 hypothetical protein 147479 2769412 LIC20123 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003514.1 146796 R 267671 CDS YP_003515.1 45655706 2769334 complement(147476..148840) 1 NC_005824.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase 148840 cobB 2769334 cobB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cobyrinic acid a,c-diamide synthase YP_003515.1 147476 R 267671 CDS YP_003516.1 45655707 2769306 complement(148840..149376) 1 NC_005824.1 corrinoid ATP adenosyltransferase 149376 cobO 2769306 cobO Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 corrinoid ATP adenosyltransferase YP_003516.1 148840 R 267671 CDS YP_003517.1 45655708 2769251 complement(149373..150137) 1 NC_005824.1 precorrin-4-methylase 150137 cobM 2769251 cobM Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 precorrin-4-methylase YP_003517.1 149373 R 267671 CDS YP_003518.1 45655709 2769325 complement(150151..151644) 1 NC_005824.1 precorrin-3 C-17 methylase 151644 cobJ 2769325 cobJ Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 precorrin-3 C-17 methylase YP_003518.1 150151 R 267671 CDS YP_003519.1 45655710 2769247 complement(151641..152798) 1 NC_005824.1 precorrin methylase 152798 cbiG 2769247 cbiG Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 precorrin methylase YP_003519.1 151641 R 267671 CDS YP_003520.1 45655711 2769310 complement(152785..153549) 1 NC_005824.1 precorrin-2 C-20 methlytransferase 153549 cobI 2769310 cobI Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 precorrin-2 C-20 methlytransferase YP_003520.1 152785 R 267671 CDS YP_003521.1 45655712 2769358 complement(153546..154781) 1 NC_005824.1 precorrin-6y methylase 154781 cobL 2769358 cobL Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 precorrin-6y methylase YP_003521.1 153546 R 267671 CDS YP_003522.1 45655713 2769461 complement(154778..155449) 1 NC_005824.1 precorrin isomerase 155449 cobH 2769461 cobH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 precorrin isomerase YP_003522.1 154778 R 267671 CDS YP_003523.1 45655714 2769418 complement(155446..156549) 1 NC_005824.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A; cobalt-precorrin-6A synthase 156549 cbiD 2769418 cbiD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cobalt-precorrin-6A synthase YP_003523.1 155446 R 267671 CDS YP_003524.1 45655715 2769383 complement(156553..157302) 1 NC_005824.1 ferredoxin-like protein 157302 2769383 LIC20133 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ferredoxin-like protein YP_003524.1 156553 R 267671 CDS YP_003525.1 45655716 2769295 complement(157308..157679) 1 NC_005824.1 hypothetical protein 157679 2769295 LIC20134 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003525.1 157308 R 267671 CDS YP_003526.1 45655717 2769338 complement(157700..158869) 1 NC_005824.1 ferredoxin 158869 2769338 LIC20135 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ferredoxin YP_003526.1 157700 R 267671 CDS YP_003527.1 45655718 2769426 161226..163349 1 NC_005824.1 hypothetical protein 163349 2769426 LIC20136 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003527.1 161226 D 267671 CDS YP_003528.1 45655719 2769455 complement(163355..163927) 1 NC_005824.1 hypothetical protein 163927 2769455 LIC20137 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003528.1 163355 R 267671 CDS YP_003529.1 45655720 2769303 163969..165858 1 NC_005824.1 capsular polysaccharide biosynthesis protein 165858 capD 2769303 capD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 capsular polysaccharide biosynthesis protein YP_003529.1 163969 D 267671 CDS YP_003530.1 45655721 2769458 165851..166321 1 NC_005824.1 hypothetical protein 166321 2769458 LIC20139 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003530.1 165851 D 267671 CDS YP_003531.1 45655722 2769400 166318..167928 1 NC_005824.1 putative permease 167928 2769400 LIC20140 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 putative permease YP_003531.1 166318 D 267671 CDS YP_003532.1 45655723 2769308 168370..169257 1 NC_005824.1 putative metalloprotease; heat shock protein HtpX 169257 htpX 2769308 htpX Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heat shock protein HtpX YP_003532.1 168370 D 267671 CDS YP_003533.1 45655724 2769416 169778..170311 1 NC_005824.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 170311 apt 2769416 apt Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 adenine phosphoribosyltransferase YP_003533.1 169778 D 267671 CDS YP_003534.1 45655725 2769329 170349..171863 1 NC_005824.1 serine protease; HtrA1 171863 htrA1 2769329 htrA1 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 HtrA1 YP_003534.1 170349 D 267671 CDS YP_003535.1 45655726 2769389 171878..173461 1 NC_005824.1 HtrA1-like protein 173461 2769389 LIC20144 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 HtrA1-like protein YP_003535.1 171878 D 267671 CDS YP_003536.1 45655727 2769404 complement(174822..176054) 1 NC_005824.1 hypothetical protein 176054 2769404 LIC20145 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003536.1 174822 R 267671 CDS YP_003537.1 45655728 2769245 complement(176051..177628) 1 NC_005824.1 hypothetical protein 177628 2769245 LIC20146 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003537.1 176051 R 267671 CDS YP_003538.1 45655729 2769353 complement(177625..178017) 1 NC_005824.1 FUR family transcriptional regulator 178017 2769353 LIC20147 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 FUR family transcriptional regulator YP_003538.1 177625 R 267671 CDS YP_003539.1 45655730 2769266 179702..180379 1 NC_005824.1 heme oxygenase 180379 hol 2769266 hol Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 heme oxygenase YP_003539.1 179702 D 267671 CDS YP_003540.1 45655731 2769293 180354..181562 1 NC_005824.1 major facilitator superfamily; identified by sequence similarity; putative; ORF located using Blastx/Glimmer; multidrug-efflux transporter 181562 2769293 LIC20149 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 multidrug-efflux transporter YP_003540.1 180354 D 267671 CDS YP_003541.1 45655732 2769313 complement(181966..182283) 1 NC_005824.1 hypothetical protein 182283 2769313 LIC20150 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003541.1 181966 R 267671 CDS YP_003542.1 45655733 2769287 complement(183184..185316) 1 NC_005824.1 tonB-dependent outer membrane receptor 185316 2769287 LIC20151 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 tonB-dependent outer membrane receptor YP_003542.1 183184 R 267671 CDS YP_003543.1 45655734 2769291 complement(185295..185996) 1 NC_005824.1 hypothetical protein 185996 2769291 LIC20152 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003543.1 185295 R 267671 CDS YP_003544.1 45655735 2769402 complement(186021..186599) 1 NC_005824.1 hypothetical protein 186599 2769402 LIC20153 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003544.1 186021 R 267671 CDS YP_003545.1 45655736 2769260 187071..187796 1 NC_005824.1 contains leucine-rich repeats; identified by sequence similarity; putative; ORF located using Blastx/Glimmer; lipoprotein 187796 2769260 LIC20154 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003545.1 187071 D 267671 CDS YP_003546.1 45655737 2769272 complement(187809..188582) 1 NC_005824.1 hypothetical protein 188582 2769272 LIC20155 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003546.1 187809 R 267671 CDS YP_003547.1 45655738 2769332 complement(189000..189305) 1 NC_005824.1 hypothetical protein 189305 2769332 LIC20156 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003547.1 189000 R 267671 CDS YP_003548.1 45655739 2769388 complement(189410..190765) 1 NC_005824.1 hypothetical protein 190765 2769388 LIC20157 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003548.1 189410 R 267671 CDS YP_003549.1 45655740 2769275 complement(191023..192645) 1 NC_005824.1 ATP-dependent protease 192645 lonA 2769275 lonA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ATP-dependent protease YP_003549.1 191023 R 267671 CDS YP_003550.1 45655741 2769457 complement(192671..193729) 1 NC_005824.1 S-adenosylmethionine--tRNA ribosyltransferase-isomerase 193729 queA 2769457 queA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_003550.1 192671 R 267671 CDS YP_003551.1 45655742 2769373 193976..195370 1 NC_005824.1 hypothetical protein 195370 2769373 LIC20160 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003551.1 193976 D 267671 CDS YP_003552.1 45655743 2769307 195390..196532 1 NC_005824.1 mannosyltransferase 196532 2769307 LIC20161 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 mannosyltransferase YP_003552.1 195390 D 267671 CDS YP_003553.1 45655744 2769267 196537..197109 1 NC_005824.1 hypothetical protein 197109 2769267 LIC20162 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003553.1 196537 D 267671 CDS YP_003554.1 45655745 2769298 197539..198927 1 NC_005824.1 hypothetical protein 198927 2769298 LIC20163 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003554.1 197539 D 267671 CDS YP_003555.1 45655746 2769349 198999..200411 1 NC_005824.1 alginate O-acetyltransferase 200411 2769349 LIC20164 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alginate O-acetyltransferase YP_003555.1 198999 D 267671 CDS YP_003556.1 45655747 2769415 200426..201586 1 NC_005824.1 hypothetical protein 201586 2769415 LIC20165 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003556.1 200426 D 267671 CDS YP_003557.1 45655748 2769300 201583..202980 1 NC_005824.1 alginate O-acetyltransferase 202980 2769300 LIC20166 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alginate O-acetyltransferase YP_003557.1 201583 D 267671 CDS YP_003558.1 45655749 2769235 202987..204057 1 NC_005824.1 hypothetical protein 204057 2769235 LIC20167 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003558.1 202987 D 267671 CDS YP_003559.1 45655750 2769385 204054..204398 1 NC_005824.1 hypothetical protein 204398 2769385 LIC20168 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003559.1 204054 D 267671 CDS YP_003560.1 45655751 2769292 complement(205175..205588) 1 NC_005824.1 ExbD/TolR biopolymer transport protein 205588 2769292 LIC20169 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ExbD/TolR biopolymer transport protein YP_003560.1 205175 R 267671 CDS YP_003561.1 45655752 2769387 complement(205585..206112) 1 NC_005824.1 MotA/TolQ/ExbB proton channel family protein 206112 2769387 LIC20170 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 MotA/TolQ/ExbB proton channel family protein YP_003561.1 205585 R 267671 CDS YP_003562.1 45655753 2769217 206725..207474 1 NC_005824.1 ubiquinone/menaquinone biosynthesis methyltransferase 207474 ubiE 2769217 ubiE Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ubiquinone/menaquinone biosynthesis methyltransferase YP_003562.1 206725 D 267671 CDS YP_003563.1 45655754 2769348 207557..209710 1 NC_005824.1 lipoprotein 209710 2769348 LIC20172 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003563.1 207557 D 267671 CDS YP_003564.1 45655755 2769315 209755..211146 1 NC_005824.1 hypothetical protein 211146 2769315 LIC20173 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003564.1 209755 D 267671 CDS YP_003565.1 45655756 2769253 complement(211129..213228) 1 NC_005824.1 hypothetical protein 213228 2769253 LIC20174 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003565.1 211129 R 267671 CDS YP_003566.1 45655757 2769453 complement(214536..214988) 1 NC_005824.1 dnaK suppressor 214988 dksA 2769453 dksA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 dnaK suppressor YP_003566.1 214536 R 267671 CDS YP_003567.1 45655758 2769375 217270..219324 1 NC_005824.1 lipoprotein 219324 2769375 LIC20176 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lipoprotein YP_003567.1 217270 D 267671 CDS YP_003568.1 45655759 2769279 219425..219958 1 NC_005824.1 FimH-like protein 219958 2769279 LIC20177 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 FimH-like protein YP_003568.1 219425 D 267671 CDS YP_003569.1 45655760 2769305 221026..222297 1 NC_005824.1 DNA binding protein 222297 2769305 LIC20178 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 DNA binding protein YP_003569.1 221026 D 267671 CDS YP_003570.1 45655761 2769326 complement(224207..224608) 1 NC_005824.1 hypothetical protein 224608 2769326 LIC20179 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003570.1 224207 R 267671 CDS YP_003571.1 45655762 2769432 complement(226084..227802) 1 NC_005824.1 response regulator 227802 2769432 LIC20180 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_003571.1 226084 R 267671 CDS YP_003572.1 45655763 2769259 complement(228268..229953) 1 NC_005824.1 GGDEF family protein 229953 2769259 LIC20181 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GGDEF family protein YP_003572.1 228268 R 267671 CDS YP_003573.1 45655764 2769265 complement(230245..231819) 1 NC_005824.1 GGDEF family protein 231819 2769265 LIC20182 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 GGDEF family protein YP_003573.1 230245 R 267671 CDS YP_003574.1 45655765 2769285 232351..234876 1 NC_005824.1 histidine kinase sensor protein 234876 2769285 LIC20183 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_003574.1 232351 D 267671 CDS YP_003576.1 45655767 2769229 complement(235359..236060) 1 NC_005824.1 hypothetical protein 236060 2769229 LIC20185 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003576.1 235359 R 267671 CDS YP_003577.1 45655768 2769244 complement(236103..236510) 1 NC_005824.1 hypothetical protein 236510 2769244 LIC20186 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003577.1 236103 R 267671 CDS YP_003578.1 45655769 2769223 complement(236793..237797) 1 NC_005824.1 hypothetical protein 237797 2769223 LIC20187 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003578.1 236793 R 267671 CDS YP_003579.1 45655770 2769451 complement(238678..240066) 1 NC_005824.1 sodium/solute symporter family protein 240066 2769451 LIC20188 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 sodium/solute symporter family protein YP_003579.1 238678 R 267671 CDS YP_003580.1 45655771 2769414 240473..240844 1 NC_005824.1 hypothetical protein 240844 2769414 LIC20189 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003580.1 240473 D 267671 CDS YP_003581.1 45655772 2769252 241108..242565 1 NC_005824.1 hypothetical protein 242565 2769252 LIC20190 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003581.1 241108 D 267671 CDS YP_003582.1 45655773 2769450 complement(243091..245055) 1 NC_005824.1 hypothetical protein 245055 2769450 LIC20191 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003582.1 243091 R 267671 CDS YP_003583.1 45655774 2769294 complement(245183..246061) 1 NC_005824.1 hypothetical protein 246061 2769294 LIC20192 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003583.1 245183 R 267671 CDS YP_003584.1 45655775 2769327 248366..249655 1 NC_005824.1 4-hydroxybutyrate CoA transferase 249655 2769327 LIC20195 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 4-hydroxybutyrate CoA transferase YP_003584.1 248366 D 267671 CDS YP_003585.1 45655776 2769261 249924..250442 1 NC_005824.1 hypothetical protein 250442 2769261 LIC20196 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003585.1 249924 D 267671 CDS YP_003586.1 45655777 2769304 250455..252854 1 NC_005824.1 cysteine protease 252854 2769304 LIC20197 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cysteine protease YP_003586.1 250455 D 267671 CDS YP_003587.1 45655778 2769465 complement(253515..254867) 1 NC_005824.1 hypothetical protein 254867 2769465 LIC20198 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003587.1 253515 R 267671 CDS YP_003588.1 45655779 2769209 complement(254973..256391) 1 NC_005824.1 UTP-glucose-1-phosphate uridyltransferase 256391 galU 2769209 galU Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 UTP-glucose-1-phosphate uridyltransferase YP_003588.1 254973 R 267671 CDS YP_003589.1 45655780 2769469 complement(256379..256828) 1 NC_005824.1 hypothetical protein 256828 2769469 LIC20200 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003589.1 256379 R 267671 CDS YP_003590.1 45655781 2769246 256838..257755 1 NC_005824.1 hypothetical protein 257755 2769246 LIC20201 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003590.1 256838 D 267671 CDS YP_003591.1 45655782 2769368 258538..259656 1 NC_005824.1 hypothetical protein 259656 2769368 LIC20202 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003591.1 258538 D 267671 CDS YP_003592.1 45655783 2769211 complement(260224..261174) 1 NC_005824.1 BASS family; identified by sequence similarity; putative; ORF located using Blastx/Glimmer; bile acid Na+ symporter 261174 yocS 2769211 yocS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 bile acid Na+ symporter YP_003592.1 260224 R 267671 CDS YP_003593.1 45655784 2769203 complement(262066..263217) 1 NC_005824.1 cysteine desulfurase 263217 csdB 2769203 csdB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cysteine desulfurase YP_003593.1 262066 R 267671 CDS YP_003594.1 45655785 2769434 complement(263228..264097) 1 NC_005824.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 264097 2769434 LIC20205 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003594.1 263228 R 267671 CDS YP_003595.1 45655786 2769280 complement(264160..264786) 1 NC_005824.1 cytoplasmic membrane protein 264786 2769280 LIC20206 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytoplasmic membrane protein YP_003595.1 264160 R 267671 CDS YP_003596.1 45655787 2769447 264874..265854 1 NC_005824.1 MFS; identified by sequence similarity; putative; ORF located using Blastx/Glimmer; major facilitator superfamily permease 265854 2769447 LIC20207 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 major facilitator superfamily permease YP_003596.1 264874 D 267671 CDS YP_003597.1 45655788 2769401 265946..267826 1 NC_005824.1 methylmalonyl-COA mutase small subunit 267826 2769401 LIC20208 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methylmalonyl-COA mutase small subunit YP_003597.1 265946 D 267671 CDS YP_003598.1 45655789 2769224 267823..270021 1 NC_005824.1 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 270021 mcmA 2769224 mcmA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 methylmalonyl-CoA mutase YP_003598.1 267823 D 267671 CDS YP_003599.1 45655790 2769225 270034..271089 1 NC_005824.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 271089 2769225 LIC20210 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 arginine/ornithine transport system ATPase YP_003599.1 270034 D 267671 CDS YP_003600.1 45655791 2769321 272181..272558 1 NC_005824.1 hypothetical protein 272558 2769321 LIC20211 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003600.1 272181 D 267671 CDS YP_003601.1 45655792 2769367 272715..273404 1 NC_005824.1 hypothetical protein 273404 2769367 LIC20212 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003601.1 272715 D 267671 CDS YP_003602.1 45655793 2769408 273406..273855 1 NC_005824.1 hypothetical protein 273855 2769408 LIC20213 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003602.1 273406 D 267671 CDS YP_003603.1 45655794 2769409 273993..276524 1 NC_005824.1 hypothetical protein 276524 2769409 LIC20214 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003603.1 273993 D 267671 CDS YP_003604.1 45655795 2769431 276524..277039 1 NC_005824.1 hypothetical protein 277039 2769431 LIC20215 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003604.1 276524 D 267671 CDS YP_003605.1 45655796 2769397 277118..277732 1 NC_005824.1 ExbB 277732 exbB 2769397 exbB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 ExbB YP_003605.1 277118 D 267671 CDS YP_003606.1 45655797 2769351 277821..278225 1 NC_005824.1 hypothetical protein 278225 exbD 2769351 exbD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003606.1 277821 D 267671 CDS YP_003607.1 45655798 2769282 278235..278885 1 NC_005824.1 hypothetical protein 278885 2769282 LIC20218 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003607.1 278235 D 267671 CDS YP_003608.1 45655799 2769302 280058..280852 1 NC_005824.1 hypothetical protein 280852 2769302 LIC20219 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003608.1 280058 D 267671 CDS YP_003609.1 45655800 2769413 280864..282516 1 NC_005824.1 glutamate synthase 282516 gltB 2769413 gltB Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 glutamate synthase YP_003609.1 280864 D 267671 CDS YP_003610.1 45655801 2769231 282852..283580 1 NC_005824.1 hypothetical protein 283580 2769231 LIC20221 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003610.1 282852 D 267671 CDS YP_003611.1 45655802 2769281 283577..284017 1 NC_005824.1 hypothetical protein 284017 2769281 LIC20222 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003611.1 283577 D 267671 CDS YP_003612.1 45655803 2769360 284151..284582 1 NC_005824.1 hypothetical protein 284582 2769360 LIC20223 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003612.1 284151 D 267671 CDS YP_003613.1 45655804 2769363 285266..287353 1 NC_005824.1 histidine kinase sensor protein 287353 2769363 LIC20224 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_003613.1 285266 D 267671 CDS YP_003614.1 45655805 2769352 complement(287357..288055) 1 NC_005824.1 3-oxoacyl-[acyl-carrier protein] reductase 288055 2769352 LIC20225 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 3-oxoacyl-[acyl-carrier protein] reductase YP_003614.1 287357 R 267671 CDS YP_003615.1 45655806 2769466 complement(288068..288817) 1 NC_005824.1 aldolase class II 288817 2769466 LIC20226 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aldolase class II YP_003615.1 288068 R 267671 CDS YP_003616.1 45655807 2769343 complement(288819..289352) 1 NC_005824.1 acireductone dioxygenase enzyme ARD and ARD' 289352 ard 2769343 ard Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 acireductone dioxygenase enzyme ARD and ARD' YP_003616.1 288819 R 267671 CDS YP_003617.1 45655808 2769324 291797..292696 1 NC_005824.1 phosphate ABC transporter periplasmic phosphate-binding protein 292696 pstS 2769324 pstS Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 phosphate ABC transporter periplasmic phosphate-binding protein YP_003617.1 291797 D 267671 CDS YP_003618.1 45655809 2769371 292771..293868 1 NC_005824.1 L-lysine 2, 3-aminomutase 293868 kamA 2769371 kamA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 L-lysine 2, 3-aminomutase YP_003618.1 292771 D 267671 CDS YP_003619.1 45655810 2769271 293843..294481 1 NC_005824.1 hypothetical protein 294481 2769271 LIC20231 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003619.1 293843 D 267671 CDS YP_003858668.1 304570518 9714935 294542..294742 1 NC_005824.1 hypothetical protein 294742 9714935 LIC20303 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003858668.1 294542 D 267671 CDS YP_003620.1 45655811 2769314 294735..295508 1 NC_005824.1 hypothetical protein 295508 2769314 LIC20232 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003620.1 294735 D 267671 CDS YP_003621.1 45655812 2769339 complement(296538..297032) 1 NC_005824.1 cytoplasmic membrane protein 297032 2769339 LIC20233 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytoplasmic membrane protein YP_003621.1 296538 R 267671 CDS YP_003622.1 45655813 2769311 complement(297462..297920) 1 NC_005824.1 cytoplasmic membrane protein 297920 2769311 LIC20234 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 cytoplasmic membrane protein YP_003622.1 297462 R 267671 CDS YP_003623.1 45655814 2769299 complement(301783..302649) 1 NC_005824.1 S-adenosylmethionine decarboxylase like protein 302649 speH 2769299 speH Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 S-adenosylmethionine decarboxylase like protein YP_003623.1 301783 R 267671 CDS YP_003624.1 45655815 2769222 complement(302749..303135) 1 NC_005824.1 Decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase proenzyme 303135 speD 2769222 speD Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 S-adenosylmethionine decarboxylase proenzyme YP_003624.1 302749 R 267671 CDS YP_003625.1 45655816 2769364 complement(303602..304144) 1 NC_005824.1 hypothetical protein 304144 2769364 LIC20240 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003625.1 303602 R 267671 CDS YP_003626.1 45655817 2769277 304174..305343 1 NC_005824.1 alanine racemase 305343 alr 2769277 alr Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alanine racemase YP_003626.1 304174 D 267671 CDS YP_003627.1 45655818 2769448 305394..306539 1 NC_005824.1 putative acyltransferase 306539 2769448 LIC20242 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 putative acyltransferase YP_003627.1 305394 D 267671 CDS YP_003628.1 45655819 2769322 306560..307471 1 NC_005824.1 hypothetical protein 307471 2769322 LIC20243 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003628.1 306560 D 267671 CDS YP_003629.1 45655820 2769435 307468..308259 1 NC_005824.1 internal repeat sequences detected; contains internal repeats as detected by prospero; hypothetical protein 308259 2769435 LIC20244 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003629.1 307468 D 267671 CDS YP_003630.1 45655821 2769403 complement(309214..309873) 1 NC_005824.1 hypothetical protein 309873 2769403 LIC20245 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003630.1 309214 R 267671 CDS YP_003631.1 45655822 2769445 complement(309874..312189) 1 NC_005824.1 histidine kinase sensor protein 312189 2769445 LIC20246 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 histidine kinase sensor protein YP_003631.1 309874 R 267671 CDS YP_003632.1 45655823 2769443 312245..312862 1 NC_005824.1 soluble lytic murein transglycosylase 312862 slt 2769443 slt Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 soluble lytic murein transglycosylase YP_003632.1 312245 D 267671 CDS YP_003633.1 45655824 2769464 complement(314619..316892) 1 NC_005824.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 316892 acnA 2769464 acnA Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aconitate hydratase YP_003633.1 314619 R 267671 CDS YP_003634.1 45655825 2769255 complement(317161..318312) 1 NC_005824.1 OmpA-like; identified by sequence similarity; putative; ORF located using Blastx/Glimmer; peptidoglycan-associated cytoplasmic membrane protein 318312 2769255 LIC20250 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 peptidoglycan-associated cytoplasmic membrane protein YP_003634.1 317161 R 267671 CDS YP_003635.1 45655826 2769284 complement(318488..319504) 1 NC_005824.1 lysyl-tRNA synthetase-like protein 319504 2769284 LIC20251 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 lysyl-tRNA synthetase-like protein YP_003635.1 318488 R 267671 CDS YP_003636.1 45655827 2769365 319708..320037 1 NC_005824.1 hypothetical protein 320037 2769365 LIC20252 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003636.1 319708 D 267671 CDS YP_003637.1 45655828 2769395 complement(320357..320767) 1 NC_005824.1 hypothetical protein 320767 2769395 LIC20253 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003637.1 320357 R 267671 CDS YP_003638.1 45655829 2769335 320975..321706 1 NC_005824.1 response regulator 321706 2769335 LIC20254 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 response regulator YP_003638.1 320975 D 267671 CDS YP_003639.1 45655830 2769369 complement(322355..322933) 1 NC_005824.1 hypothetical protein 322933 2769369 LIC20255 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003639.1 322355 R 267671 CDS YP_003640.1 45655831 2769377 complement(322936..323346) 1 NC_005824.1 pterin-4-alpha-carbinolamine dehydratase 323346 phs 2769377 phs Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pterin-4-alpha-carbinolamine dehydratase YP_003640.1 322936 R 267671 CDS YP_003641.1 45655832 2769204 323845..324417 1 NC_005824.1 hypothetical protein 324417 2769204 LIC20257 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003641.1 323845 D 267671 CDS YP_003642.1 45655833 2769234 complement(324821..325267) 1 NC_005824.1 hypothetical protein 325267 2769234 LIC20258 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003642.1 324821 R 267671 CDS YP_003643.1 45655834 2769220 complement(325324..325737) 1 NC_005824.1 hypothetical protein 325737 2769220 LIC20259 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003643.1 325324 R 267671 CDS YP_003858669.1 304570516 9714936 325976..326254 1 NC_005824.1 hypothetical protein 326254 9714936 LIC20301 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003858669.1 325976 D 267671 CDS YP_003644.1 45655835 2769394 326271..326654 1 NC_005824.1 hypothetical protein 326654 2769394 LIC20260 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003644.1 326271 D 267671 CDS YP_003858670.1 304570515 9714940 326774..326920 1 NC_005824.1 hypothetical protein 326920 9714940 LIC20300 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003858670.1 326774 D 267671 CDS YP_003645.1 45655836 2769317 327025..327492 1 NC_005824.1 hypothetical protein 327492 2769317 LIC20261 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003645.1 327025 D 267671 CDS YP_003646.1 45655837 2769212 328768..329208 1 NC_005824.1 hypothetical protein 329208 2769212 LIC20262 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003646.1 328768 D 267671 CDS YP_003647.1 45655838 2769424 complement(331031..331408) 1 NC_005824.1 hypothetical protein 331408 2769424 LIC20263 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003647.1 331031 R 267671 CDS YP_003648.1 45655839 2769428 complement(331662..333122) 1 NC_005824.1 pyruvate kinase 333122 pykF 2769428 pykF Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 pyruvate kinase YP_003648.1 331662 R 267671 CDS YP_003649.1 45655840 2769372 complement(333161..335122) 1 NC_005824.1 hypothetical protein 335122 2769372 LIC20265 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003649.1 333161 R 267671 CDS YP_003650.1 45655841 2769470 complement(335135..336184) 1 NC_005824.1 catalyzes the formation of aspartate semialdehyde from aspartyl phosphate; aspartate-semialdehyde dehydrogenase 336184 asd 2769470 asd Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 aspartate-semialdehyde dehydrogenase YP_003650.1 335135 R 267671 CDS YP_003651.1 45655842 2769214 complement(336236..336691) 1 NC_005824.1 hypothetical protein 336691 2769214 LIC20267 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003651.1 336236 R 267671 CDS YP_003652.1 45655843 2769393 338378..339943 1 NC_005824.1 hypothetical protein 339943 2769393 LIC20268 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003652.1 338378 D 267671 CDS YP_003653.1 45655844 2769370 complement(339914..341377) 1 NC_005824.1 alginate O-acetyltransferase 341377 2769370 LIC20269 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 alginate O-acetyltransferase YP_003653.1 339914 R 267671 CDS YP_003654.1 45655845 2769319 complement(343104..343490) 1 NC_005824.1 hypothetical protein 343490 2769319 LIC20270 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003654.1 343104 R 267671 CDS YP_003655.1 45655846 2769240 complement(343533..344507) 1 NC_005824.1 hypothetical protein 344507 2769240 LIC20271 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003655.1 343533 R 267671 CDS YP_003656.1 45655847 2769297 complement(344590..345663) 1 NC_005824.1 hypothetical protein 345663 2769297 LIC20272 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003656.1 344590 R 267671 CDS YP_003657.1 45655848 2769422 complement(345602..346972) 1 NC_005824.1 putative transcriptional regulator 346972 2769422 LIC20273 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 putative transcriptional regulator YP_003657.1 345602 R 267671 CDS YP_003658.1 45655849 2769430 347217..347969 1 NC_005824.1 chromosome partitioning; identified by sequence similarity; putative; ORF located using Blastx/Glimmer; hypothetical protein 347969 2769430 LIC20274 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003658.1 347217 D 267671 CDS YP_003659.1 45655850 2769256 347953..348798 1 NC_005824.1 chromosome partitioning; identified by sequence similarity; putative; ORF located using Blastx/Glimmer; hypothetical protein 348798 2769256 LIC20275 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003659.1 347953 D 267671 CDS YP_003660.1 45655851 2769221 349231..350169 1 NC_005824.1 hypothetical protein 350169 2769221 LIC20276 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 hypothetical protein YP_003660.1 349231 D 267671 CDS