-- dump date   	20140619_093938
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1094466000001	ribonuclease R; Region: RNase_R; TIGR02063
1094466000002	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1094466000003	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1094466000004	RNB domain; Region: RNB; pfam00773
1094466000005	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1094466000006	RNA binding site [nucleotide binding]; other site
1094466000007	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
1094466000008	LysE type translocator; Region: LysE; cl00565
1094466000009	Dihydroneopterin aldolase; Region: FolB; smart00905
1094466000010	active site
1094466000011	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1094466000012	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1094466000013	active site
1094466000014	nucleotide binding site [chemical binding]; other site
1094466000015	HIGH motif; other site
1094466000016	KMSKS motif; other site
1094466000017	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1094466000018	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1094466000019	Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_like_u4; cd03407
1094466000020	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
1094466000021	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1094466000022	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1094466000023	active site
1094466000024	HIGH motif; other site
1094466000025	KMSKS motif; other site
1094466000026	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
1094466000027	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1094466000028	Domain of unknown function (DUF4175); Region: DUF4175; pfam13779
1094466000029	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
1094466000030	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1094466000031	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1094466000032	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1094466000033	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466000034	S-adenosylmethionine binding site [chemical binding]; other site
1094466000035	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
1094466000036	PIF1-like helicase; Region: PIF1; pfam05970
1094466000037	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1094466000038	ATP binding site [chemical binding]; other site
1094466000039	putative Mg++ binding site [ion binding]; other site
1094466000040	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
1094466000041	Helix-turn-helix domain; Region: HTH_40; pfam14493
1094466000042	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1094466000043	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1094466000044	Walker A/P-loop; other site
1094466000045	ATP binding site [chemical binding]; other site
1094466000046	Q-loop/lid; other site
1094466000047	ABC transporter signature motif; other site
1094466000048	Walker B; other site
1094466000049	D-loop; other site
1094466000050	H-loop/switch region; other site
1094466000051	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1094466000052	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1094466000053	FtsX-like permease family; Region: FtsX; pfam02687
1094466000054	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1094466000055	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cl00019
1094466000056	ADP-ribose binding site [chemical binding]; other site
1094466000057	HlyD family secretion protein; Region: HlyD_3; pfam13437
1094466000058	Outer membrane efflux protein; Region: OEP; pfam02321
1094466000059	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1094466000060	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
1094466000061	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1094466000062	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1094466000063	DNA polymerase III, delta' subunit; Region: holB; TIGR00678
1094466000064	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1094466000065	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1094466000066	substrate binding site [chemical binding]; other site
1094466000067	hinge regions; other site
1094466000068	ADP binding site [chemical binding]; other site
1094466000069	catalytic site [active]
1094466000070	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1094466000071	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1094466000072	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1094466000073	catalytic residue [active]
1094466000074	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1094466000075	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1094466000076	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1094466000077	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1094466000078	Coenzyme A binding pocket [chemical binding]; other site
1094466000079	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466000080	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1094466000081	ligand binding site [chemical binding]; other site
1094466000082	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466000083	ligand binding site [chemical binding]; other site
1094466000084	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1094466000085	C-terminal peptidase (prc); Region: prc; TIGR00225
1094466000086	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1094466000087	protein binding site [polypeptide binding]; other site
1094466000088	Catalytic dyad [active]
1094466000089	ribonuclease P; Reviewed; Region: rnpA; PRK01903
1094466000090	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
1094466000091	Zn binding site [ion binding]; other site
1094466000092	Peptidase S8 family domain in Subtilisin_Novo-like proteins; Region: Peptidases_S8_Subtilisin_Novo-like; cd07483
1094466000093	catalytic triad [active]
1094466000094	active site
1094466000095	Subtilase family; Region: Peptidase_S8; pfam00082
1094466000096	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1094466000097	Peptidase family M48; Region: Peptidase_M48; cl12018
1094466000098	Peptidase family M48; Region: Peptidase_M48; cl12018
1094466000099	Bacterial protein of unknown function (DUF898); Region: DUF898; pfam05987
1094466000100	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1094466000101	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1094466000102	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
1094466000103	FeS assembly ATPase SufC; Region: sufC; TIGR01978
1094466000104	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1094466000105	Walker A/P-loop; other site
1094466000106	ATP binding site [chemical binding]; other site
1094466000107	Q-loop/lid; other site
1094466000108	ABC transporter signature motif; other site
1094466000109	Walker B; other site
1094466000110	D-loop; other site
1094466000111	H-loop/switch region; other site
1094466000112	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
1094466000113	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
1094466000114	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1094466000115	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1094466000116	catalytic residue [active]
1094466000117	Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones]; Region: sufE; COG2166
1094466000118	FeS assembly SUF system protein; Region: SUF_assoc; TIGR02945
1094466000119	Protein of unknown function (DUF2480); Region: DUF2480; pfam10652
1094466000120	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
1094466000121	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1094466000122	HflX GTPase family; Region: HflX; cd01878
1094466000123	G1 box; other site
1094466000124	GTP/Mg2+ binding site [chemical binding]; other site
1094466000125	Switch I region; other site
1094466000126	G2 box; other site
1094466000127	G3 box; other site
1094466000128	Switch II region; other site
1094466000129	G4 box; other site
1094466000130	G5 box; other site
1094466000131	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1094466000132	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1094466000133	Interdomain contacts; other site
1094466000134	Cytokine receptor motif; other site
1094466000135	CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; Region: CUB; cd00041
1094466000136	heterodimerization interface [polypeptide binding]; other site
1094466000137	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1094466000138	Interdomain contacts; other site
1094466000139	Cytokine receptor motif; other site
1094466000140	Lamin Tail Domain; Region: LTD; pfam00932
1094466000141	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
1094466000142	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
1094466000143	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466000144	TPR motif; other site
1094466000145	TPR repeat; Region: TPR_11; pfam13414
1094466000146	binding surface
1094466000147	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
1094466000148	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1094466000149	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1094466000150	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1094466000151	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466000152	ligand binding site [chemical binding]; other site
1094466000153	Uncharacterized ACR, COG2135; Region: DUF159; pfam02586
1094466000154	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1094466000155	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1094466000156	active site
1094466000157	DNA binding site [nucleotide binding]
1094466000158	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1094466000159	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1094466000160	Catalytic site [active]
1094466000161	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1094466000162	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1094466000163	G1 box; other site
1094466000164	GTP/Mg2+ binding site [chemical binding]; other site
1094466000165	G2 box; other site
1094466000166	Switch I region; other site
1094466000167	G3 box; other site
1094466000168	Switch II region; other site
1094466000169	G4 box; other site
1094466000170	G5 box; other site
1094466000171	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1094466000172	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
1094466000173	active site
1094466000174	catalytic site [active]
1094466000175	substrate binding site [chemical binding]; other site
1094466000176	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1094466000177	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1094466000178	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1094466000179	DNA binding site [nucleotide binding]
1094466000180	active site
1094466000181	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
1094466000182	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1094466000183	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1094466000184	dimer interface [polypeptide binding]; other site
1094466000185	phosphorylation site [posttranslational modification]
1094466000186	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466000187	ATP binding site [chemical binding]; other site
1094466000188	Mg2+ binding site [ion binding]; other site
1094466000189	G-X-G motif; other site
1094466000190	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1094466000191	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466000192	active site
1094466000193	phosphorylation site [posttranslational modification]
1094466000194	intermolecular recognition site; other site
1094466000195	dimerization interface [polypeptide binding]; other site
1094466000196	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1094466000197	DNA binding site [nucleotide binding]
1094466000198	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
1094466000199	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
1094466000200	active site
1094466000201	Zn binding site [ion binding]; other site
1094466000202	Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only]; Region: COG4447
1094466000203	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466000204	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
1094466000205	Cu(I) binding site [ion binding]; other site
1094466000206	Divergent AAA domain; Region: AAA_4; pfam04326
1094466000207	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1094466000208	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
1094466000209	active site
1094466000210	catalytic tetrad [active]
1094466000211	MoxR-like ATPases [General function prediction only]; Region: COG0714
1094466000212	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466000213	Walker A motif; other site
1094466000214	ATP binding site [chemical binding]; other site
1094466000215	Walker B motif; other site
1094466000216	arginine finger; other site
1094466000217	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
1094466000218	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1094466000219	metal ion-dependent adhesion site (MIDAS); other site
1094466000220	hypothetical protein; Provisional; Region: PRK13685
1094466000221	Aerotolerance regulator N-terminal; Region: BatA; pfam07584
1094466000222	VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_BatA_type; cd01467
1094466000223	metal ion-dependent adhesion site (MIDAS); other site
1094466000224	von Willebrand factor type A domain; Region: VWA_2; pfam13519
1094466000225	metal ion-dependent adhesion site (MIDAS); other site
1094466000226	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466000227	binding surface
1094466000228	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1094466000229	TPR motif; other site
1094466000230	Oxygen tolerance; Region: BatD; pfam13584
1094466000231	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466000232	binding surface
1094466000233	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1094466000234	TPR motif; other site
1094466000235	Two component regulator propeller; Region: Reg_prop; pfam07494
1094466000236	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466000237	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1094466000238	Recombination protein O N terminal; Region: RecO_N; pfam11967
1094466000239	Recombination protein O C terminal; Region: RecO_C; pfam02565
1094466000240	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
1094466000241	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1094466000242	active site
1094466000243	HIGH motif; other site
1094466000244	nucleotide binding site [chemical binding]; other site
1094466000245	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1094466000246	active site
1094466000247	KMSKS motif; other site
1094466000248	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
1094466000249	tRNA binding surface [nucleotide binding]; other site
1094466000250	anticodon binding site; other site
1094466000251	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cl00723
1094466000252	DnaK suppressor protein [Signal transduction mechanisms]; Region: DksA; COG1734
1094466000253	DNA polymerase III PolC; Validated; Region: polC; PRK00448
1094466000254	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1094466000255	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1094466000256	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1094466000257	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1094466000258	active site
1094466000259	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
1094466000260	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1094466000261	5S rRNA interface [nucleotide binding]; other site
1094466000262	CTC domain interface [polypeptide binding]; other site
1094466000263	L16 interface [polypeptide binding]; other site
1094466000264	Ribosomal protein TL5, C-terminal domain; Region: Ribosomal_TL5_C; pfam14693
1094466000265	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1094466000266	homodimer interface [polypeptide binding]; other site
1094466000267	substrate-cofactor binding pocket; other site
1094466000268	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466000269	catalytic residue [active]
1094466000270	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466000271	TPR motif; other site
1094466000272	binding surface
1094466000273	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1094466000274	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466000275	binding surface
1094466000276	TPR motif; other site
1094466000277	seryl-tRNA synthetase; Provisional; Region: PRK05431
1094466000278	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1094466000279	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1094466000280	motif 1; other site
1094466000281	dimer interface [polypeptide binding]; other site
1094466000282	active site
1094466000283	motif 2; other site
1094466000284	motif 3; other site
1094466000285	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
1094466000286	Zn binding site [ion binding]; other site
1094466000287	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466000288	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1094466000289	RIP metalloprotease RseP; Region: TIGR00054
1094466000290	active site
1094466000291	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1094466000292	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1094466000293	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1094466000294	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1094466000295	putative substrate binding region [chemical binding]; other site
1094466000296	Helix-turn-helix domain; Region: HTH_17; pfam12728
1094466000297	Phage protein Gp37/Gp68; Region: Gp37_Gp68; cl15384
1094466000298	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
1094466000299	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1094466000300	non-specific DNA binding site [nucleotide binding]; other site
1094466000301	salt bridge; other site
1094466000302	sequence-specific DNA binding site [nucleotide binding]; other site
1094466000303	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1094466000304	MPN+ (JAMM) motif; other site
1094466000305	Zinc-binding site [ion binding]; other site
1094466000306	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1094466000307	non-specific DNA binding site [nucleotide binding]; other site
1094466000308	salt bridge; other site
1094466000309	sequence-specific DNA binding site [nucleotide binding]; other site
1094466000310	Domain of unknown function (DUF4365); Region: DUF4365; pfam14280
1094466000311	Piwi_piwi-like_ProArk: PIWI domain, Piwi-like subfamily found in Archaea and Bacteria. RNA silencing refers to a group of related gene-silencing mechanisms mediated by short RNA molecules, including siRNAs, miRNAs, and heterochromatin-related guide RNAs; Region: Piwi_piwi-like_ProArk; cd04659
1094466000312	5' RNA guide strand anchoring site; other site
1094466000313	active site
1094466000314	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl18944
1094466000315	putative transposase OrfB; Reviewed; Region: PHA02517
1094466000316	HTH-like domain; Region: HTH_21; pfam13276
1094466000317	Integrase core domain; Region: rve; pfam00665
1094466000318	Integrase core domain; Region: rve_3; pfam13683
1094466000319	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1094466000320	Transposase; Region: HTH_Tnp_1; cl17663
1094466000321	Domain of unknown function, B. Theta Gene description (DUF3871); Region: DUF3871; pfam12987
1094466000322	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1094466000323	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1094466000324	Phage integrase SAM-like domain; Region: Phage_int_SAM_5; pfam13102
1094466000325	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1094466000326	active site
1094466000327	DNA binding site [nucleotide binding]
1094466000328	Int/Topo IB signature motif; other site
1094466000329	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1094466000330	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1094466000331	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1094466000332	dimer interface [polypeptide binding]; other site
1094466000333	motif 1; other site
1094466000334	active site
1094466000335	motif 2; other site
1094466000336	motif 3; other site
1094466000337	Colicin V production protein; Region: Colicin_V; pfam02674
1094466000338	Cytochrome c; Region: Cytochrom_C; cl11414
1094466000339	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
1094466000340	dimer interface [polypeptide binding]; other site
1094466000341	allosteric magnesium binding site [ion binding]; other site
1094466000342	active site
1094466000343	aspartate-rich active site metal binding site; other site
1094466000344	Schiff base residues; other site
1094466000345	23S rRNA-intervening sequence protein; Region: 23S_rRNA_IVP; pfam05635
1094466000346	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1094466000347	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1094466000348	substrate binding site [chemical binding]; other site
1094466000349	active site
1094466000350	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1094466000351	active site
1094466000352	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1094466000353	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1094466000354	domain interfaces; other site
1094466000355	active site
1094466000356	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1094466000357	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
1094466000358	NAD(P) binding pocket [chemical binding]; other site
1094466000359	Glutamyl-tRNAGlu reductase, dimerization domain; Region: GlutR_dimer; pfam00745
1094466000360	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1094466000361	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1094466000362	ferrochelatase; Reviewed; Region: hemH; PRK00035
1094466000363	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1094466000364	C-terminal domain interface [polypeptide binding]; other site
1094466000365	active site
1094466000366	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1094466000367	active site
1094466000368	N-terminal domain interface [polypeptide binding]; other site
1094466000369	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
1094466000370	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1094466000371	HAMP domain; Region: HAMP; pfam00672
1094466000372	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1094466000373	dimer interface [polypeptide binding]; other site
1094466000374	phosphorylation site [posttranslational modification]
1094466000375	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466000376	ATP binding site [chemical binding]; other site
1094466000377	Mg2+ binding site [ion binding]; other site
1094466000378	G-X-G motif; other site
1094466000379	3-hydroxybutyryl-CoA dehydratase; Validated; Region: PRK05809
1094466000380	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1094466000381	substrate binding site [chemical binding]; other site
1094466000382	oxyanion hole (OAH) forming residues; other site
1094466000383	trimer interface [polypeptide binding]; other site
1094466000384	lipoprotein signal peptidase; Provisional; Region: PRK14788
1094466000385	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
1094466000386	Protein of unknown function (DUF2591); Region: DUF2591; cl11584
1094466000387	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466000388	TonB-dependent receptor; Region: TonB-Xanth-Caul; TIGR01782
1094466000389	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466000390	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1094466000391	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466000392	active site
1094466000393	phosphorylation site [posttranslational modification]
1094466000394	intermolecular recognition site; other site
1094466000395	dimerization interface [polypeptide binding]; other site
1094466000396	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1094466000397	DNA binding site [nucleotide binding]
1094466000398	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1094466000399	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1094466000400	dimer interface [polypeptide binding]; other site
1094466000401	phosphorylation site [posttranslational modification]
1094466000402	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466000403	ATP binding site [chemical binding]; other site
1094466000404	Mg2+ binding site [ion binding]; other site
1094466000405	G-X-G motif; other site
1094466000406	conserved hypothetical protein; Region: MJ1255; TIGR00661
1094466000407	Glycosyltransferase family 28 C-terminal domain; Region: Glyco_tran_28_C; cl19139
1094466000408	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466000409	S-adenosylmethionine binding site [chemical binding]; other site
1094466000410	LysE type translocator; Region: LysE; cl00565
1094466000411	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1094466000412	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1094466000413	DNA binding site [nucleotide binding]
1094466000414	active site
1094466000415	chaperonin_like superfamily. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. There are 2 main chaperonin groups. The symmetry of type I...; Region: chaperonin_like; cl02777
1094466000416	Domain of unknown function DUF59; Region: DUF59; pfam01883
1094466000417	cell division ATPase MinD, archaeal; Region: minD_arch; TIGR01969
1094466000418	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1094466000419	Walker A motif; other site
1094466000420	NifU-like domain; Region: NifU; cl00484
1094466000421	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1094466000422	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1094466000423	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1094466000424	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cl00159
1094466000425	S-adenosylmethionine decarboxylase; Region: AdoMet_dc; cl00687
1094466000426	Domain of unknown function (DUF4178); Region: DUF4178; pfam13785
1094466000427	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1094466000428	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1094466000429	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466000430	S-adenosylmethionine binding site [chemical binding]; other site
1094466000431	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1094466000432	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1094466000433	active site
1094466000434	DNA binding site [nucleotide binding]
1094466000435	Int/Topo IB signature motif; other site
1094466000436	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1094466000437	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1094466000438	non-specific DNA binding site [nucleotide binding]; other site
1094466000439	salt bridge; other site
1094466000440	sequence-specific DNA binding site [nucleotide binding]; other site
1094466000441	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1094466000442	sequence-specific DNA binding site [nucleotide binding]; other site
1094466000443	salt bridge; other site
1094466000444	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1094466000445	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1094466000446	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1094466000447	Immunity protein 33; Region: Imm33; pfam15580
1094466000448	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1094466000449	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466000450	Phage associated DNA primase [General function prediction only]; Region: COG3378
1094466000451	Helix-turn-helix domain; Region: HTH_17; cl17695
1094466000452	Subtilase family; Region: Peptidase_S8; pfam00082
1094466000453	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
1094466000454	active site
1094466000455	catalytic residues [active]
1094466000456	Proprotein convertase P-domain; Region: P_proprotein; pfam01483
1094466000457	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466000458	hypothetical protein; Provisional; Region: PRK08201
1094466000459	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_3; cd05680
1094466000460	metal binding site [ion binding]; metal-binding site
1094466000461	putative dimer interface [polypeptide binding]; other site
1094466000462	30S ribosomal protein S16; Provisional; Region: rpsP; PRK14521
1094466000463	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1094466000464	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1094466000465	RimM N-terminal domain; Region: RimM; pfam01782
1094466000466	PRC-barrel domain; Region: PRC; pfam05239
1094466000467	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1094466000468	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466000469	S-adenosylmethionine binding site [chemical binding]; other site
1094466000470	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1094466000471	HlyD family secretion protein; Region: HlyD_3; pfam13437
1094466000472	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1094466000473	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
1094466000474	putative active site [active]
1094466000475	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1094466000476	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466000477	Walker A/P-loop; other site
1094466000478	ATP binding site [chemical binding]; other site
1094466000479	Q-loop/lid; other site
1094466000480	ABC transporter signature motif; other site
1094466000481	Walker B; other site
1094466000482	D-loop; other site
1094466000483	H-loop/switch region; other site
1094466000484	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
1094466000485	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1094466000486	catalytic residues [active]
1094466000487	Vitamin K epoxide reductase (VKOR) family in bacteria; Region: VKOR_4; cd12921
1094466000488	putative active site [active]
1094466000489	redox center [active]
1094466000490	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1094466000491	Thioredoxin; Region: Thioredoxin_4; cl17273
1094466000492	SPASM domain peptide maturase, grasp-with-spasm system; Region: SPASM_w_grasp; TIGR04193
1094466000493	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1094466000494	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1094466000495	ATP-grasp ribosomal peptide maturase, MvdC family; Region: ATPgraspMvdC; TIGR04185
1094466000496	type 2 lantibiotic, SP_1948 family; Region: lant_SP_1948; TIGR03893
1094466000497	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1094466000498	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1094466000499	active site
1094466000500	Protein of unknown function (DUF3050); Region: DUF3050; pfam11251
1094466000501	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
1094466000502	Alpha amylase catalytic domain found in an uncharacterized protein family; Region: AmyAc_4; cd11350
1094466000503	trehalose synthase; Region: treS_nterm; TIGR02456
1094466000504	active site
1094466000505	catalytic site [active]
1094466000506	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466000507	SusE outer membrane protein; Region: SusE; pfam14292
1094466000508	Uncharacterized subgroup of the CBM-SusE-F_like superfamily; Region: CBM_SusE-F_like_u1; cd12967
1094466000509	starch binding site [chemical binding]; other site
1094466000510	carbohydrate-binding modules from Bacteroides thetaiotaomicron SusE, SusF and similar proteins; Region: CBM_SusE-F_like; cd12956
1094466000511	starch binding site [chemical binding]; other site
1094466000512	starch binding outer membrane protein SusD; Region: SusD; cd08977
1094466000513	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
1094466000514	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466000515	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1094466000516	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466000517	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1094466000518	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1094466000519	DNA binding site [nucleotide binding]
1094466000520	domain linker motif; other site
1094466000521	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1094466000522	dimerization interface [polypeptide binding]; other site
1094466000523	ligand binding site [chemical binding]; other site
1094466000524	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1094466000525	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1094466000526	putative substrate translocation pore; other site
1094466000527	beta-phosphoglucomutase; Region: bPGM; TIGR01990
1094466000528	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1094466000529	maltose phosphorylase; Provisional; Region: PRK13807
1094466000530	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
1094466000531	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
1094466000532	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
1094466000533	Glycosyl-hydrolase 97 N-terminal; Region: GH97_N; pfam14508
1094466000534	Glycoside hydrolase 97; Region: Glyco_hydro_97; pfam10566
1094466000535	Glycosyl-hydrolase 97 C-terminal, oligomerization; Region: GH97_C; pfam14509
1094466000536	Cyclomaltodextrinase, N-terminal; Region: Cyc-maltodext_N; pfam09087
1094466000537	Alpha amylase catalytic domain found in bacterial cyclomaltodextrinases and related proteins; Region: AmyAc_bac_CMD_like_3; cd11340
1094466000538	Ca binding site [ion binding]; other site
1094466000539	Alpha amylase, catalytic domain; Region: Alpha-amylase; pfam00128
1094466000540	active site
1094466000541	homodimer interface [polypeptide binding]; other site
1094466000542	catalytic site [active]
1094466000543	Cyclo-malto-dextrinase C-terminal domain; Region: Cyc-maltodext_C; pfam10438
1094466000544	Putative esterase; Region: Esterase; pfam00756
1094466000545	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1094466000546	Alpha amylase catalytic domain found in archaeal and bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_arch_bac_AmyA; cd11313
1094466000547	Alpha amylase, catalytic domain; Region: Alpha-amylase; pfam00128
1094466000548	active site
1094466000549	catalytic site [active]
1094466000550	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
1094466000551	catalytic motif [active]
1094466000552	Catalytic residue [active]
1094466000553	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1094466000554	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1094466000555	putative substrate translocation pore; other site
1094466000556	RNA polymerase sigma-54 factor; Region: rpoN_sigma; TIGR02395
1094466000557	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1094466000558	Interdomain contacts; other site
1094466000559	Cytokine receptor motif; other site
1094466000560	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1094466000561	Interdomain contacts; other site
1094466000562	Cytokine receptor motif; other site
1094466000563	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1094466000564	Interdomain contacts; other site
1094466000565	Cytokine receptor motif; other site
1094466000566	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1094466000567	Interdomain contacts; other site
1094466000568	Cytokine receptor motif; other site
1094466000569	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1094466000570	Interdomain contacts; other site
1094466000571	Cytokine receptor motif; other site
1094466000572	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1094466000573	Interdomain contacts; other site
1094466000574	Cytokine receptor motif; other site
1094466000575	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466000576	Helix-turn-helix domain; Region: HTH_18; pfam12833
1094466000577	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1094466000578	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1094466000579	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1094466000580	E3 interaction surface; other site
1094466000581	lipoyl attachment site [posttranslational modification]; other site
1094466000582	e3 binding domain; Region: E3_binding; pfam02817
1094466000583	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1094466000584	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1094466000585	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1094466000586	TPP-binding site [chemical binding]; other site
1094466000587	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1094466000588	dimer interface [polypeptide binding]; other site
1094466000589	PYR/PP interface [polypeptide binding]; other site
1094466000590	TPP binding site [chemical binding]; other site
1094466000591	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1094466000592	substrate binding pocket [chemical binding]; other site
1094466000593	chain length determination region; other site
1094466000594	substrate-Mg2+ binding site; other site
1094466000595	catalytic residues [active]
1094466000596	aspartate-rich region 1; other site
1094466000597	active site lid residues [active]
1094466000598	aspartate-rich region 2; other site
1094466000599	YceI-like domain; Region: YceI; cl01001
1094466000600	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1094466000601	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1094466000602	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1094466000603	Outer membrane efflux protein; Region: OEP; pfam02321
1094466000604	Outer membrane efflux protein; Region: OEP; pfam02321
1094466000605	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1094466000606	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
1094466000607	HlyD family secretion protein; Region: HlyD_3; pfam13437
1094466000608	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1094466000609	MMPL family; Region: MMPL; cl14618
1094466000610	MMPL family; Region: MMPL; cl14618
1094466000611	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1094466000612	putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase; Provisional; Region: PRK11930
1094466000613	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1094466000614	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1094466000615	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1094466000616	active site
1094466000617	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1094466000618	dimer interface [polypeptide binding]; other site
1094466000619	substrate binding site [chemical binding]; other site
1094466000620	catalytic residues [active]
1094466000621	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1094466000622	active site
1094466000623	putative substrate binding region [chemical binding]; other site
1094466000624	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
1094466000625	putative acyl-acceptor binding pocket; other site
1094466000626	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
1094466000627	Uncharacterized protein conserved in bacteria (DUF2141); Region: DUF2141; pfam09912
1094466000628	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1094466000629	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1094466000630	NAD(P) binding site [chemical binding]; other site
1094466000631	active site
1094466000632	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1094466000633	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1094466000634	dimer interface [polypeptide binding]; other site
1094466000635	active site
1094466000636	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
1094466000637	active site 1 [active]
1094466000638	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
1094466000639	active site 2 [active]
1094466000640	active site 1 [active]
1094466000641	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1094466000642	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1094466000643	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1094466000644	Outer membrane protein beta-barrel family; Region: OMP_b-brl_3; pfam14905
1094466000645	Uncharacterized protein conserved in bacteria (DUF2141); Region: DUF2141; pfam09912
1094466000646	thymidine kinase; Provisional; Region: PRK04296
1094466000647	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1094466000648	putative SAM binding site [chemical binding]; other site
1094466000649	putative homodimer interface [polypeptide binding]; other site
1094466000650	HopJ type III effector protein; Region: HopJ; pfam08888
1094466000651	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1094466000652	DHH family; Region: DHH; pfam01368
1094466000653	DHHA1 domain; Region: DHHA1; pfam02272
1094466000654	H+ Antiporter protein; Region: 2A0121; TIGR00900
1094466000655	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1094466000656	putative substrate translocation pore; other site
1094466000657	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1094466000658	putative active site [active]
1094466000659	putative metal binding site [ion binding]; other site
1094466000660	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1094466000661	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1094466000662	Interdomain contacts; other site
1094466000663	Cytokine receptor motif; other site
1094466000664	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1094466000665	Interdomain contacts; other site
1094466000666	Cytokine receptor motif; other site
1094466000667	CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; Region: CUB; cd00041
1094466000668	heterodimerization interface [polypeptide binding]; other site
1094466000669	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1094466000670	Interdomain contacts; other site
1094466000671	Cytokine receptor motif; other site
1094466000672	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
1094466000673	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
1094466000674	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466000675	TPR motif; other site
1094466000676	TPR repeat; Region: TPR_11; pfam13414
1094466000677	binding surface
1094466000678	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
1094466000679	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1094466000680	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1094466000681	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1094466000682	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466000683	ligand binding site [chemical binding]; other site
1094466000684	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466000685	TonB dependent receptor; Region: TonB_dep_Rec; cl17754
1094466000686	GLPGLI family protein; Region: GLPGLI; TIGR01200
1094466000687	CAAX protease self-immunity; Region: Abi; pfam02517
1094466000688	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1094466000689	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1094466000690	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1094466000691	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1094466000692	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
1094466000693	HpaII restriction endonuclease; Region: RE_HpaII; pfam09561
1094466000694	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1094466000695	cofactor binding site; other site
1094466000696	DNA binding site [nucleotide binding]
1094466000697	substrate interaction site [chemical binding]; other site
1094466000698	Putative serine esterase (DUF676); Region: DUF676; pfam05057
1094466000699	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
1094466000700	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466000701	Endonuclease/Exonuclease/phosphatase family; Region: Exo_endo_phos; pfam03372
1094466000702	putative catalytic site [active]
1094466000703	putative metal binding site [ion binding]; other site
1094466000704	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
1094466000705	Restriction endonuclease; Region: Mrr_cat; cl19295
1094466000706	AAA ATPase domain; Region: AAA_16; pfam13191
1094466000707	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1094466000708	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1094466000709	active site
1094466000710	DNA binding site [nucleotide binding]
1094466000711	Int/Topo IB signature motif; other site
1094466000712	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
1094466000713	active site
1094466000714	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
1094466000715	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
1094466000716	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1094466000717	substrate binding site [chemical binding]; other site
1094466000718	oxyanion hole (OAH) forming residues; other site
1094466000719	trimer interface [polypeptide binding]; other site
1094466000720	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1094466000721	Thiol-disulfide isomerase and thioredoxins [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: TrxA; COG0526
1094466000722	Outer membrane protein Omp28; Region: Omp28; pfam11551
1094466000723	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1094466000724	catalytic residues [active]
1094466000725	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; cl17415
1094466000726	CAAX protease self-immunity; Region: Abi; pfam02517
1094466000727	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
1094466000728	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
1094466000729	homodimer interface [polypeptide binding]; other site
1094466000730	catalytic residues [active]
1094466000731	NAD binding site [chemical binding]; other site
1094466000732	substrate binding pocket [chemical binding]; other site
1094466000733	flexible flap; other site
1094466000734	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1094466000735	PAS domain; Region: PAS_9; pfam13426
1094466000736	putative active site [active]
1094466000737	heme pocket [chemical binding]; other site
1094466000738	PAS domain S-box; Region: sensory_box; TIGR00229
1094466000739	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1094466000740	putative active site [active]
1094466000741	heme pocket [chemical binding]; other site
1094466000742	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1094466000743	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1094466000744	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1094466000745	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1094466000746	putative active site [active]
1094466000747	heme pocket [chemical binding]; other site
1094466000748	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1094466000749	dimer interface [polypeptide binding]; other site
1094466000750	phosphorylation site [posttranslational modification]
1094466000751	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466000752	ATP binding site [chemical binding]; other site
1094466000753	Mg2+ binding site [ion binding]; other site
1094466000754	G-X-G motif; other site
1094466000755	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466000756	active site
1094466000757	phosphorylation site [posttranslational modification]
1094466000758	intermolecular recognition site; other site
1094466000759	dimerization interface [polypeptide binding]; other site
1094466000760	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
1094466000761	X-Pro dipeptidyl-peptidase (S15 family); Region: Peptidase_S15; pfam02129
1094466000762	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1094466000763	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1094466000764	POT family; Region: PTR2; cl17359
1094466000765	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1094466000766	putative substrate translocation pore; other site
1094466000767	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1094466000768	POT family; Region: PTR2; cl17359
1094466000769	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1094466000770	putative substrate translocation pore; other site
1094466000771	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1094466000772	POT family; Region: PTR2; cl17359
1094466000773	Thioredoxin-like; Region: Thioredoxin_7; pfam13899
1094466000774	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1094466000775	Competence protein; Region: Competence; pfam03772
1094466000776	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1094466000777	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1094466000778	Beta-lactamase; Region: Beta-lactamase; pfam00144
1094466000779	Domain of unknown function (DUF3471); Region: DUF3471; pfam11954
1094466000780	Nicotinamide mononucleotide transporter; Region: NMN_transporter; cl01256
1094466000781	DNA polymerase I; Provisional; Region: PRK05755
1094466000782	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1094466000783	active site
1094466000784	metal binding site 1 [ion binding]; metal-binding site
1094466000785	putative 5' ssDNA interaction site; other site
1094466000786	metal binding site 3; metal-binding site
1094466000787	metal binding site 2 [ion binding]; metal-binding site
1094466000788	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1094466000789	putative DNA binding site [nucleotide binding]; other site
1094466000790	putative metal binding site [ion binding]; other site
1094466000791	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1094466000792	active site
1094466000793	catalytic site [active]
1094466000794	substrate binding site [chemical binding]; other site
1094466000795	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1094466000796	active site
1094466000797	DNA binding site [nucleotide binding]
1094466000798	catalytic site [active]
1094466000799	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1094466000800	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
1094466000801	putative active site [active]
1094466000802	putative metal binding site [ion binding]; other site
1094466000803	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1094466000804	catalytic residues [active]
1094466000805	delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884
1094466000806	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
1094466000807	NodB motif; other site
1094466000808	active site
1094466000809	catalytic site [active]
1094466000810	metal binding site [ion binding]; metal-binding site
1094466000811	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
1094466000812	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1094466000813	Ligand Binding Site [chemical binding]; other site
1094466000814	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1094466000815	Ligand Binding Site [chemical binding]; other site
1094466000816	Sm and related proteins; Region: Sm_like; cl00259
1094466000817	heptamer interface [polypeptide binding]; other site
1094466000818	Sm1 motif; other site
1094466000819	hexamer interface [polypeptide binding]; other site
1094466000820	RNA binding site [nucleotide binding]; other site
1094466000821	Sm2 motif; other site
1094466000822	transcription termination factor NusA; Region: NusA; TIGR01953
1094466000823	NusA N-terminal domain; Region: NusA_N; pfam08529
1094466000824	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1094466000825	RNA binding site [nucleotide binding]; other site
1094466000826	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1094466000827	G-X-X-G motif; other site
1094466000828	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1094466000829	G-X-X-G motif; other site
1094466000830	translation initiation factor IF-2; Validated; Region: infB; PRK05306
1094466000831	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1094466000832	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1094466000833	G1 box; other site
1094466000834	putative GEF interaction site [polypeptide binding]; other site
1094466000835	GTP/Mg2+ binding site [chemical binding]; other site
1094466000836	Switch I region; other site
1094466000837	G2 box; other site
1094466000838	G3 box; other site
1094466000839	Switch II region; other site
1094466000840	G4 box; other site
1094466000841	G5 box; other site
1094466000842	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1094466000843	Translation-initiation factor 2; Region: IF-2; pfam11987
1094466000844	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1094466000845	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1094466000846	salicylyl-CoA 5-hydroxylase; Reviewed; Region: PRK08255
1094466000847	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1094466000848	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
1094466000849	active site
1094466000850	FMN binding site [chemical binding]; other site
1094466000851	substrate binding site [chemical binding]; other site
1094466000852	homotetramer interface [polypeptide binding]; other site
1094466000853	catalytic residue [active]
1094466000854	four helix bundle protein; Region: TIGR02436
1094466000855	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1094466000856	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
1094466000857	acyl-activating enzyme (AAE) consensus motif; other site
1094466000858	AMP binding site [chemical binding]; other site
1094466000859	active site
1094466000860	CoA binding site [chemical binding]; other site
1094466000861	Glutamate synthase domain 2 [Amino acid transport and metabolism]; Region: GltB; COG0069
1094466000862	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1094466000863	active site
1094466000864	FMN binding site [chemical binding]; other site
1094466000865	substrate binding site [chemical binding]; other site
1094466000866	3Fe-4S cluster binding site [ion binding]; other site
1094466000867	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1094466000868	active site
1094466000869	Nitrilases, cyanide hydratase (CH)s, and similar proteins (class 1 nitrilases); Region: nitrilases_CHs; cd07564
1094466000870	putative active site [active]
1094466000871	catalytic triad [active]
1094466000872	putative dimer interface [polypeptide binding]; other site
1094466000873	Gentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3435
1094466000874	Cupin domain; Region: Cupin_2; pfam07883
1094466000875	Cupin domain; Region: Cupin_2; pfam07883
1094466000876	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1094466000877	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1094466000878	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1094466000879	Sporulation related domain; Region: SPOR; pfam05036
1094466000880	Cytochrome c; Region: Cytochrom_C; pfam00034
1094466000881	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1094466000882	Heme-binding domain of the class III cytochrome C family and related proteins; Region: Cytochrom_C3; cd08168
1094466000883	heme-binding residues [chemical binding]; other site
1094466000884	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1094466000885	molybdopterin cofactor binding site; other site
1094466000886	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
1094466000887	molybdopterin cofactor binding site; other site
1094466000888	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1094466000889	4Fe-4S binding domain; Region: Fer4; pfam00037
1094466000890	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1094466000891	Polysulphide reductase, NrfD; Region: NrfD; cl19193
1094466000892	Protein of unknown function (DUF3341); Region: DUF3341; pfam11821
1094466000893	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1094466000894	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1094466000895	cytochrome c oxidase, subunit II; Region: CoxB; TIGR02866
1094466000896	Cytochrome C oxidase subunit II, transmembrane domain; Region: COX2_TM; pfam02790
1094466000897	Cupredoxin superfamily; Region: Cupredoxin; cl19115
1094466000898	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1094466000899	cytochrome c oxidase, subunit I; Region: CtaD_CoxA; TIGR02891
1094466000900	Domain of unknown function (DUF4286); Region: DUF4286; pfam14114
1094466000901	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1094466000902	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1094466000903	MgtE intracellular N domain; Region: MgtE_N; pfam03448
1094466000904	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1094466000905	Divalent cation transporter; Region: MgtE; pfam01769
1094466000906	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1094466000907	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466000908	Walker A motif; other site
1094466000909	ATP binding site [chemical binding]; other site
1094466000910	Walker B motif; other site
1094466000911	arginine finger; other site
1094466000912	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1094466000913	four helix bundle protein; Region: TIGR02436
1094466000914	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1094466000915	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
1094466000916	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1094466000917	Peptidase M76 family; Region: Peptidase_M76; pfam09768
1094466000918	Transposase IS200 like; Region: Y1_Tnp; cl00848
1094466000919	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1094466000920	FOG: WD40 repeat [General function prediction only]; Region: COG2319
1094466000921	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1094466000922	Immunoglobulin domain; Region: Ig_2; pfam13895
1094466000923	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1094466000924	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1094466000925	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1094466000926	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1094466000927	putative NAD(P) binding site [chemical binding]; other site
1094466000928	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1094466000929	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1094466000930	RuvA N terminal domain; Region: RuvA_N; pfam01330
1094466000931	Helix-hairpin-helix domain; Region: HHH_5; pfam14520
1094466000932	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1094466000933	cell surface protein SprA; Region: surface_SprA; TIGR04189
1094466000934	Motility related/secretion protein; Region: SprA_N; pfam14349
1094466000935	Motility related/secretion protein; Region: SprA_N; pfam14349
1094466000936	Motility related/secretion protein; Region: SprA_N; pfam14349
1094466000937	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1094466000938	lipoyl attachment site [posttranslational modification]; other site
1094466000939	Class I aldolases; Region: Aldolase_Class_I; cl17187
1094466000940	catalytic residue [active]
1094466000941	Protoheme IX farnesyltransferase; Region: PT_UbiA_Cox10; cd13957
1094466000942	putative active site [active]
1094466000943	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
1094466000944	Subunit I/III interface [polypeptide binding]; other site
1094466000945	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
1094466000946	Subunit I/III interface [polypeptide binding]; other site
1094466000947	Prokaryotic Cytochrome C oxidase subunit IV; Region: COX4_pro; pfam03626
1094466000948	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
1094466000949	Cu(I) binding site [ion binding]; other site
1094466000950	Protein of unknown function (DUF420); Region: DUF420; pfam04238
1094466000951	Domain of unknown function (DUF4403); Region: DUF4403; pfam14356
1094466000952	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1094466000953	Outer membrane efflux protein; Region: OEP; pfam02321
1094466000954	Outer membrane efflux protein; Region: OEP; pfam02321
1094466000955	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1094466000956	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1094466000957	HlyD family secretion protein; Region: HlyD_3; pfam13437
1094466000958	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1094466000959	Glycoprotease family; Region: Peptidase_M22; pfam00814
1094466000960	Conserved TM helix; Region: TM_helix; pfam05552
1094466000961	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1094466000962	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; pfam08712
1094466000963	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; pfam08712
1094466000964	NifU-like domain; Region: NifU; cl00484
1094466000965	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1094466000966	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
1094466000967	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1094466000968	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1094466000969	trimer interface [polypeptide binding]; other site
1094466000970	putative metal binding site [ion binding]; other site
1094466000971	glutamate racemase; Provisional; Region: PRK00865
1094466000972	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
1094466000973	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
1094466000974	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
1094466000975	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1094466000976	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1094466000977	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1094466000978	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1094466000979	Surface antigen; Region: Bac_surface_Ag; pfam01103
1094466000980	Cis (Z)-Isoprenyl Diphosphate Synthases; Region: Cis_IPPS; cd00475
1094466000981	active site
1094466000982	dimer interface [polypeptide binding]; other site
1094466000983	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK01911
1094466000984	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
1094466000985	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1094466000986	active site
1094466000987	hydrophilic channel; other site
1094466000988	dimerization interface [polypeptide binding]; other site
1094466000989	catalytic residues [active]
1094466000990	active site lid [active]
1094466000991	Putative lysophospholipase; Region: Hydrolase_4; cl19140
1094466000992	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1094466000993	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
1094466000994	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
1094466000995	catalytic triad [active]
1094466000996	Membrane protein of unknown function; Region: DUF360; pfam04020
1094466000997	Bacterial trigger factor protein (TF); Region: Trigger_N; pfam05697
1094466000998	trigger factor; Region: tig; TIGR00115
1094466000999	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1094466001000	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1094466001001	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1094466001002	oligomer interface [polypeptide binding]; other site
1094466001003	active site residues [active]
1094466001004	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1094466001005	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1094466001006	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466001007	Walker A motif; other site
1094466001008	ATP binding site [chemical binding]; other site
1094466001009	Walker B motif; other site
1094466001010	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1094466001011	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1094466001012	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1094466001013	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1094466001014	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466001015	ligand binding site [chemical binding]; other site
1094466001016	GH3 auxin-responsive promoter; Region: GH3; pfam03321
1094466001017	indole-3-acetic acid-amido synthetase; Region: PLN02249
1094466001018	Protein of unknown function (DUF2797); Region: DUF2797; pfam10977
1094466001019	Protein of unknown function (DUF3078); Region: DUF3078; pfam11276
1094466001020	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1094466001021	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1094466001022	TPP-binding site; other site
1094466001023	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1094466001024	PYR/PP interface [polypeptide binding]; other site
1094466001025	dimer interface [polypeptide binding]; other site
1094466001026	TPP binding site [chemical binding]; other site
1094466001027	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1094466001028	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1094466001029	nucleoside/Zn binding site; other site
1094466001030	dimer interface [polypeptide binding]; other site
1094466001031	catalytic motif [active]
1094466001032	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1094466001033	MG2 domain; Region: A2M_N; pfam01835
1094466001034	Alpha-2-macroglobulin family N-terminal region; Region: A2M_N_2; pfam07703
1094466001035	Alpha-2-macroglobulin family; Region: A2M; pfam00207
1094466001036	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1094466001037	surface patch; other site
1094466001038	thioester region; other site
1094466001039	specificity defining residues; other site
1094466001040	penicillin-binding protein 1C; Region: PBP_1c; TIGR02073
1094466001041	Transglycosylase; Region: Transgly; pfam00912
1094466001042	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1094466001043	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1094466001044	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
1094466001045	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1094466001046	homodimer interface [polypeptide binding]; other site
1094466001047	oligonucleotide binding site [chemical binding]; other site
1094466001048	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
1094466001049	Beta subunit of integration host factor (IHFB); Region: IHF_B; cd13836
1094466001050	dimer interface [polypeptide binding]; other site
1094466001051	DNA binding site [nucleotide binding]
1094466001052	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
1094466001053	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1094466001054	minor groove reading motif; other site
1094466001055	helix-hairpin-helix signature motif; other site
1094466001056	substrate binding pocket [chemical binding]; other site
1094466001057	active site
1094466001058	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1094466001059	DNA binding and oxoG recognition site [nucleotide binding]
1094466001060	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1094466001061	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1094466001062	dimer interface [polypeptide binding]; other site
1094466001063	ssDNA binding site [nucleotide binding]; other site
1094466001064	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1094466001065	gliding motility-associated lipoprotein GldD; Region: GldD_lipo; TIGR03512
1094466001066	TraB family; Region: TraB; pfam01963
1094466001067	HEAT repeats; Region: HEAT_2; pfam13646
1094466001068	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; pfam02592
1094466001069	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
1094466001070	Uncharacterized conserved protein (DUF2132); Region: DUF2132; pfam09905
1094466001071	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1094466001072	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1094466001073	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466001074	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1094466001075	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466001076	active site
1094466001077	phosphorylation site [posttranslational modification]
1094466001078	intermolecular recognition site; other site
1094466001079	dimerization interface [polypeptide binding]; other site
1094466001080	LytTr DNA-binding domain; Region: LytTR; smart00850
1094466001081	Histidine kinase; Region: HisKA_2; pfam07568
1094466001082	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1094466001083	Domain of unknown function (DUF3127); Region: DUF3127; pfam11325
1094466001084	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
1094466001085	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1094466001086	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1094466001087	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1094466001088	phosphorylation site [posttranslational modification]
1094466001089	dimer interface [polypeptide binding]; other site
1094466001090	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466001091	ATP binding site [chemical binding]; other site
1094466001092	Mg2+ binding site [ion binding]; other site
1094466001093	G-X-G motif; other site
1094466001094	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
1094466001095	nucleotide binding site/active site [active]
1094466001096	HIT family signature motif; other site
1094466001097	catalytic residue [active]
1094466001098	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1094466001099	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1094466001100	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1094466001101	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
1094466001102	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1094466001103	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466001104	hypothetical protein; Provisional; Region: PRK09256
1094466001105	Domain of unknown function (DUF4301); Region: DUF4301; pfam14134
1094466001106	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
1094466001107	geranylgeranylglyceryl phosphate synthase-like protein; Reviewed; Region: PRK04169
1094466001108	phosphate binding site [ion binding]; other site
1094466001109	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1094466001110	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1094466001111	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
1094466001112	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
1094466001113	homotetramer interface [polypeptide binding]; other site
1094466001114	ligand binding site [chemical binding]; other site
1094466001115	catalytic site [active]
1094466001116	NAD binding site [chemical binding]; other site
1094466001117	Domain of unknown function (DUF4407); Region: DUF4407; pfam14362
1094466001118	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1094466001119	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1094466001120	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1094466001121	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1094466001122	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1094466001123	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1094466001124	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1094466001125	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1094466001126	EamA-like transporter family; Region: EamA; pfam00892
1094466001127	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1094466001128	EamA-like transporter family; Region: EamA; pfam00892
1094466001129	elongation factor Ts; Provisional; Region: tsf; PRK09377
1094466001130	UBA/TS-N domain; Region: UBA; pfam00627
1094466001131	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1094466001132	rRNA interaction site [nucleotide binding]; other site
1094466001133	S8 interaction site; other site
1094466001134	putative laminin-1 binding site; other site
1094466001135	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1094466001136	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1094466001137	23S rRNA interface [nucleotide binding]; other site
1094466001138	L3 interface [polypeptide binding]; other site
1094466001139	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1094466001140	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1094466001141	DNA binding site [nucleotide binding]
1094466001142	domain linker motif; other site
1094466001143	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1094466001144	dimerization interface [polypeptide binding]; other site
1094466001145	ligand binding site [chemical binding]; other site
1094466001146	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1094466001147	carboxy-terminal protease; Provisional; Region: PRK11186
1094466001148	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1094466001149	protein binding site [polypeptide binding]; other site
1094466001150	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1094466001151	Catalytic dyad [active]
1094466001152	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1094466001153	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
1094466001154	active site
1094466001155	substrate binding site [chemical binding]; other site
1094466001156	Mg2+ binding site [ion binding]; other site
1094466001157	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
1094466001158	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1094466001159	Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717
1094466001160	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1094466001161	rod shape-determining protein MreC; Provisional; Region: PRK13922
1094466001162	rod shape-determining protein MreB; Provisional; Region: PRK13927
1094466001163	MreB and similar proteins; Region: MreB_like; cd10225
1094466001164	nucleotide binding site [chemical binding]; other site
1094466001165	Mg binding site [ion binding]; other site
1094466001166	putative protofilament interaction site [polypeptide binding]; other site
1094466001167	RodZ interaction site [polypeptide binding]; other site
1094466001168	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1094466001169	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1094466001170	purine monophosphate binding site [chemical binding]; other site
1094466001171	dimer interface [polypeptide binding]; other site
1094466001172	putative catalytic residues [active]
1094466001173	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1094466001174	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1094466001175	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1094466001176	FtsX-like permease family; Region: FtsX; pfam02687
1094466001177	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1094466001178	active site
1094466001179	dimer interface [polypeptide binding]; other site
1094466001180	asparagine synthase (glutamine-hydrolyzing); Region: asn_synth_AEB; TIGR01536
1094466001181	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1094466001182	Ligand Binding Site [chemical binding]; other site
1094466001183	Molecular Tunnel; other site
1094466001184	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1094466001185	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1094466001186	TonB dependent receptor; Region: TonB_dep_Rec; cl17754
1094466001187	GLPGLI family protein; Region: GLPGLI; TIGR01200
1094466001188	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466001189	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
1094466001190	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
1094466001191	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
1094466001192	Substrate-binding site [chemical binding]; other site
1094466001193	Substrate specificity [chemical binding]; other site
1094466001194	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
1094466001195	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1094466001196	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
1094466001197	Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU)...; Region: Glycosylasparaginase; cd04513
1094466001198	active site
1094466001199	dimer interface [polypeptide binding]; other site
1094466001200	catalytic nucleophile [active]
1094466001201	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
1094466001202	N-acetyl-beta-hexosaminidase [Carbohydrate transport and metabolism]; Region: Chb; COG3525
1094466001203	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
1094466001204	active site
1094466001205	Fn3 associated; Region: Fn3_assoc; pfam13287
1094466001206	Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; Region: FA58C; cl19067
1094466001207	membrane-bound proton-translocating pyrophosphatase; Validated; Region: hppA; PRK00733
1094466001208	Inorganic H+ pyrophosphatase; Region: H_PPase; pfam03030
1094466001209	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1094466001210	dimer interface [polypeptide binding]; other site
1094466001211	substrate binding site [chemical binding]; other site
1094466001212	metal binding sites [ion binding]; metal-binding site
1094466001213	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]; Region: AlkA; COG0122
1094466001214	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1094466001215	minor groove reading motif; other site
1094466001216	helix-hairpin-helix signature motif; other site
1094466001217	substrate binding pocket [chemical binding]; other site
1094466001218	active site
1094466001219	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466001220	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1094466001221	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1094466001222	alpha subunit interface [polypeptide binding]; other site
1094466001223	TPP binding site [chemical binding]; other site
1094466001224	heterodimer interface [polypeptide binding]; other site
1094466001225	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1094466001226	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1094466001227	Ligand binding site [chemical binding]; other site
1094466001228	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1094466001229	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1094466001230	Ligand Binding Site [chemical binding]; other site
1094466001231	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1094466001232	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
1094466001233	Bifunctional nuclease; Region: DNase-RNase; pfam02577
1094466001234	UvrB/uvrC motif; Region: UVR; pfam02151
1094466001235	Nucleoside H+ symporter; Region: Nuc_H_symport; pfam03825
1094466001236	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1094466001237	putative substrate translocation pore; other site
1094466001238	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1094466001239	dimerization interface [polypeptide binding]; other site
1094466001240	active site
1094466001241	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
1094466001242	Gram-negative bacterial TonB protein C-terminal; Region: TonB_C; cl10048
1094466001243	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1094466001244	folate binding site [chemical binding]; other site
1094466001245	NADP+ binding site [chemical binding]; other site
1094466001246	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
1094466001247	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466001248	S-adenosylmethionine binding site [chemical binding]; other site
1094466001249	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
1094466001250	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1094466001251	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1094466001252	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1094466001253	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
1094466001254	Surface antigen; Region: Bac_surface_Ag; pfam01103
1094466001255	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1094466001256	active site
1094466001257	intersubunit interface [polypeptide binding]; other site
1094466001258	zinc binding site [ion binding]; other site
1094466001259	Na+ binding site [ion binding]; other site
1094466001260	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; cl19172
1094466001261	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
1094466001262	trimer interface [polypeptide binding]; other site
1094466001263	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
1094466001264	trimer interface [polypeptide binding]; other site
1094466001265	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
1094466001266	trimer interface [polypeptide binding]; other site
1094466001267	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
1094466001268	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1094466001269	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1094466001270	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1094466001271	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1094466001272	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466001273	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1094466001274	homodimer interface [polypeptide binding]; other site
1094466001275	substrate-cofactor binding pocket; other site
1094466001276	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466001277	catalytic residue [active]
1094466001278	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1094466001279	Homoserine acetyltransferase [Amino acid transport and metabolism]; Region: MET2; COG2021
1094466001280	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1094466001281	AAK_AK-HSDH-like: Amino Acid Kinase Superfamily (AAK), AK-HSDH-like; this family includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK- homoserine dehydrogenase (HSDH). These aspartokinases are found in such...; Region: AAK_AK-HSDH-like; cd04243
1094466001282	putative catalytic residues [active]
1094466001283	nucleotide binding site [chemical binding]; other site
1094466001284	aspartate binding site [chemical binding]; other site
1094466001285	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1094466001286	dimer interface [polypeptide binding]; other site
1094466001287	putative threonine allosteric regulatory site; other site
1094466001288	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1094466001289	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1094466001290	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1094466001291	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
1094466001292	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1094466001293	homodimer interface [polypeptide binding]; other site
1094466001294	substrate-cofactor binding pocket; other site
1094466001295	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466001296	catalytic residue [active]
1094466001297	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1094466001298	23S rRNA-intervening sequence protein; Region: 23S_rRNA_IVP; pfam05635
1094466001299	Methionine synthase I, cobalamin-binding domain [Amino acid transport and metabolism]; Region: MetH; COG1410
1094466001300	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1094466001301	substrate binding pocket [chemical binding]; other site
1094466001302	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1094466001303	B12 binding site [chemical binding]; other site
1094466001304	cobalt ligand [ion binding]; other site
1094466001305	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1094466001306	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1094466001307	FAD binding site [chemical binding]; other site
1094466001308	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1094466001309	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466001310	TPR motif; other site
1094466001311	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
1094466001312	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
1094466001313	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1094466001314	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
1094466001315	active site
1094466001316	ATP binding site [chemical binding]; other site
1094466001317	cryptochrome, DASH family; Region: crypto_DASH; TIGR02765
1094466001318	DNA photolyase; Region: DNA_photolyase; pfam00875
1094466001319	FAD binding domain of DNA photolyase; Region: FAD_binding_7; pfam03441
1094466001320	Uncharacterized protein related to deoxyribodipyrimidine photolyase [General function prediction only]; Region: COG3046
1094466001321	Deoxyribodipyrimidine photo-lyase-related protein; Region: DPRP; pfam04244
1094466001322	FAD binding domain of DNA photolyase; Region: FAD_binding_7; pfam03441
1094466001323	Protein of unknown function (DUF2805); Region: DUF2805; pfam10985
1094466001324	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1094466001325	classical (c) SDRs; Region: SDR_c; cd05233
1094466001326	NAD(P) binding site [chemical binding]; other site
1094466001327	active site
1094466001328	GTP cyclohydrolase I; Region: GTP_cyclohydroI; pfam01227
1094466001329	active site
1094466001330	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
1094466001331	Prephenate dehydratase; Region: PDT; pfam00800
1094466001332	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1094466001333	putative L-Phe binding site [chemical binding]; other site
1094466001334	DAHP synthetase I family; Region: DAHP_synth_1; cl17225
1094466001335	Chorismate mutase type II; Region: CM_2; smart00830
1094466001336	GTPase RsgA; Reviewed; Region: PRK00098
1094466001337	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
1094466001338	RNA binding site [nucleotide binding]; other site
1094466001339	homodimer interface [polypeptide binding]; other site
1094466001340	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1094466001341	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1094466001342	GTP/Mg2+ binding site [chemical binding]; other site
1094466001343	G4 box; other site
1094466001344	G5 box; other site
1094466001345	G1 box; other site
1094466001346	Switch I region; other site
1094466001347	G2 box; other site
1094466001348	G3 box; other site
1094466001349	Switch II region; other site
1094466001350	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1094466001351	putative active site [active]
1094466001352	dimerization interface [polypeptide binding]; other site
1094466001353	putative tRNAtyr binding site [nucleotide binding]; other site
1094466001354	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1094466001355	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
1094466001356	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1094466001357	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1094466001358	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs; Region: NTP-PPase_BsYpjD; cd11531
1094466001359	homodimer interface [polypeptide binding]; other site
1094466001360	metal binding site [ion binding]; metal-binding site
1094466001361	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1094466001362	5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; Region: AroA; COG0128
1094466001363	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1094466001364	hinge; other site
1094466001365	active site
1094466001366	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
1094466001367	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1094466001368	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466001369	active site
1094466001370	phosphorylation site [posttranslational modification]
1094466001371	intermolecular recognition site; other site
1094466001372	dimerization interface [polypeptide binding]; other site
1094466001373	LytTr DNA-binding domain; Region: LytTR; smart00850
1094466001374	Histidine kinase; Region: His_kinase; pfam06580
1094466001375	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466001376	ATP binding site [chemical binding]; other site
1094466001377	Mg2+ binding site [ion binding]; other site
1094466001378	G-X-G motif; other site
1094466001379	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1094466001380	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1094466001381	intermolecular salt bridges; other site
1094466001382	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466001383	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
1094466001384	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466001385	Walker A/P-loop; other site
1094466001386	ATP binding site [chemical binding]; other site
1094466001387	Q-loop/lid; other site
1094466001388	ABC transporter signature motif; other site
1094466001389	Walker B; other site
1094466001390	D-loop; other site
1094466001391	H-loop/switch region; other site
1094466001392	Permease; Region: Permease; pfam02405
1094466001393	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1094466001394	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
1094466001395	DXD motif; other site
1094466001396	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1094466001397	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
1094466001398	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1094466001399	dimer interface [polypeptide binding]; other site
1094466001400	active site
1094466001401	CoA binding pocket [chemical binding]; other site
1094466001402	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
1094466001403	heme-binding site [chemical binding]; other site
1094466001404	glycine dehydrogenase; Provisional; Region: PRK05367
1094466001405	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1094466001406	tetramer interface [polypeptide binding]; other site
1094466001407	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466001408	catalytic residue [active]
1094466001409	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG1003
1094466001410	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1094466001411	catalytic residue [active]
1094466001412	UbiA family of prenyltransferases (PTases); Region: PT_UbiA; cl00337
1094466001413	putative active site [active]
1094466001414	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_3; cd07820
1094466001415	putative hydrophobic ligand binding site [chemical binding]; other site
1094466001416	MarR family; Region: MarR_2; cl17246
1094466001417	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1094466001418	dimerization interface [polypeptide binding]; other site
1094466001419	putative DNA binding site [nucleotide binding]; other site
1094466001420	putative Zn2+ binding site [ion binding]; other site
1094466001421	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
1094466001422	Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504
1094466001423	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
1094466001424	active site
1094466001425	Zn binding site [ion binding]; other site
1094466001426	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466001427	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
1094466001428	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1094466001429	active site
1094466001430	Zn binding site [ion binding]; other site
1094466001431	AIR carboxylase; Region: AIRC; pfam00731
1094466001432	Glycoprotein UL132; Region: gpUL132; pfam11359
1094466001433	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1094466001434	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1094466001435	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1094466001436	active site
1094466001437	adenylate kinase; Reviewed; Region: adk; PRK00279
1094466001438	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1094466001439	AMP-binding site [chemical binding]; other site
1094466001440	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1094466001441	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1094466001442	Domain of unknown function DUF21; Region: DUF21; pfam01595
1094466001443	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1094466001444	Transporter associated domain; Region: CorC_HlyC; smart01091
1094466001445	GTPase CgtA; Reviewed; Region: obgE; PRK12299
1094466001446	GTP1/OBG; Region: GTP1_OBG; pfam01018
1094466001447	Obg GTPase; Region: Obg; cd01898
1094466001448	G1 box; other site
1094466001449	GTP/Mg2+ binding site [chemical binding]; other site
1094466001450	Switch I region; other site
1094466001451	G2 box; other site
1094466001452	G3 box; other site
1094466001453	Switch II region; other site
1094466001454	G4 box; other site
1094466001455	G5 box; other site
1094466001456	Peptidase S46; Region: Peptidase_S46; pfam10459
1094466001457	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466001458	TPR motif; other site
1094466001459	binding surface
1094466001460	UDP-N-acetylmuramate-alanine ligase [Cell envelope biogenesis, outer membrane]; Region: MurC; COG0773
1094466001461	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1094466001462	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1094466001463	Domain of unknown function (DUF1287); Region: DUF1287; pfam06940
1094466001464	hypothetical protein; Reviewed; Region: PRK00024
1094466001465	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1094466001466	MPN+ (JAMM) motif; other site
1094466001467	Zinc-binding site [ion binding]; other site
1094466001468	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1094466001469	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1094466001470	Walker A/P-loop; other site
1094466001471	ATP binding site [chemical binding]; other site
1094466001472	Q-loop/lid; other site
1094466001473	ABC transporter signature motif; other site
1094466001474	Walker B; other site
1094466001475	D-loop; other site
1094466001476	H-loop/switch region; other site
1094466001477	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1094466001478	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1094466001479	FtsX-like permease family; Region: FtsX; pfam02687
1094466001480	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
1094466001481	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1094466001482	motif II; other site
1094466001483	recombination factor protein RarA; Reviewed; Region: PRK13342
1094466001484	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466001485	Walker A motif; other site
1094466001486	ATP binding site [chemical binding]; other site
1094466001487	Walker B motif; other site
1094466001488	arginine finger; other site
1094466001489	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1094466001490	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1094466001491	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
1094466001492	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1094466001493	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1094466001494	Surface antigen; Region: Bac_surface_Ag; pfam01103
1094466001495	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1094466001496	S17 interaction site [polypeptide binding]; other site
1094466001497	S8 interaction site; other site
1094466001498	16S rRNA interaction site [nucleotide binding]; other site
1094466001499	streptomycin interaction site [chemical binding]; other site
1094466001500	23S rRNA interaction site [nucleotide binding]; other site
1094466001501	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1094466001502	30S ribosomal protein S7; Validated; Region: PRK05302
1094466001503	elongation factor G; Reviewed; Region: PRK12739
1094466001504	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1094466001505	G1 box; other site
1094466001506	putative GEF interaction site [polypeptide binding]; other site
1094466001507	GTP/Mg2+ binding site [chemical binding]; other site
1094466001508	Switch I region; other site
1094466001509	G2 box; other site
1094466001510	G3 box; other site
1094466001511	Switch II region; other site
1094466001512	G4 box; other site
1094466001513	G5 box; other site
1094466001514	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1094466001515	Elongation Factor G, domain II; Region: EFG_II; pfam14492
1094466001516	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1094466001517	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1094466001518	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1094466001519	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1094466001520	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1094466001521	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1094466001522	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1094466001523	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1094466001524	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1094466001525	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1094466001526	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1094466001527	putative translocon binding site; other site
1094466001528	protein-rRNA interface [nucleotide binding]; other site
1094466001529	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1094466001530	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1094466001531	G-X-X-G motif; other site
1094466001532	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1094466001533	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1094466001534	23S rRNA interface [nucleotide binding]; other site
1094466001535	5S rRNA interface [nucleotide binding]; other site
1094466001536	putative antibiotic binding site [chemical binding]; other site
1094466001537	L25 interface [polypeptide binding]; other site
1094466001538	L27 interface [polypeptide binding]; other site
1094466001539	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1094466001540	23S rRNA interface [nucleotide binding]; other site
1094466001541	putative translocon interaction site; other site
1094466001542	signal recognition particle (SRP54) interaction site; other site
1094466001543	L23 interface [polypeptide binding]; other site
1094466001544	trigger factor interaction site; other site
1094466001545	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1094466001546	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1094466001547	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1094466001548	RNA binding site [nucleotide binding]; other site
1094466001549	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1094466001550	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1094466001551	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1094466001552	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1094466001553	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1094466001554	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1094466001555	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1094466001556	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1094466001557	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1094466001558	5S rRNA interface [nucleotide binding]; other site
1094466001559	L27 interface [polypeptide binding]; other site
1094466001560	23S rRNA interface [nucleotide binding]; other site
1094466001561	L5 interface [polypeptide binding]; other site
1094466001562	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1094466001563	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1094466001564	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1094466001565	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1094466001566	23S rRNA binding site [nucleotide binding]; other site
1094466001567	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1094466001568	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1094466001569	SecY translocase; Region: SecY; pfam00344
1094466001570	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1094466001571	rRNA binding site [nucleotide binding]; other site
1094466001572	predicted 30S ribosome binding site; other site
1094466001573	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
1094466001574	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1094466001575	30S ribosomal protein S11; Validated; Region: PRK05309
1094466001576	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1094466001577	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1094466001578	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1094466001579	RNA binding surface [nucleotide binding]; other site
1094466001580	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1094466001581	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1094466001582	alphaNTD homodimer interface [polypeptide binding]; other site
1094466001583	alphaNTD - beta interaction site [polypeptide binding]; other site
1094466001584	alphaNTD - beta' interaction site [polypeptide binding]; other site
1094466001585	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1094466001586	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1094466001587	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1094466001588	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
1094466001589	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1094466001590	catalytic site [active]
1094466001591	subunit interface [polypeptide binding]; other site
1094466001592	enolase; Provisional; Region: eno; PRK00077
1094466001593	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1094466001594	dimer interface [polypeptide binding]; other site
1094466001595	metal binding site [ion binding]; metal-binding site
1094466001596	substrate binding pocket [chemical binding]; other site
1094466001597	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1094466001598	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1094466001599	dimer interface [polypeptide binding]; other site
1094466001600	active site
1094466001601	citrylCoA binding site [chemical binding]; other site
1094466001602	NADH binding [chemical binding]; other site
1094466001603	cationic pore residues; other site
1094466001604	oxalacetate/citrate binding site [chemical binding]; other site
1094466001605	coenzyme A binding site [chemical binding]; other site
1094466001606	catalytic triad [active]
1094466001607	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1094466001608	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
1094466001609	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1094466001610	catalytic residue [active]
1094466001611	Agmatinase and related proteins; Region: Agmatinase-like_2; cd11593
1094466001612	putative active site [active]
1094466001613	Mn binding site [ion binding]; other site
1094466001614	CbiD; Region: CbiD; cl00828
1094466001615	YMGG-like Gly-zipper; Region: Gly-zipper_YMGG; pfam13441
1094466001616	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
1094466001617	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1094466001618	Cupin domain; Region: Cupin_2; pfam07883
1094466001619	Protein of unknown function, DUF486; Region: DUF486; cl01236
1094466001620	Domain of unknown function DUF87; Region: DUF87; cl19135
1094466001621	AAA-like domain; Region: AAA_10; pfam12846
1094466001622	Zonular occludens toxin (Zot); Region: Zot; cl17485
1094466001623	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
1094466001624	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1094466001625	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1094466001626	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1094466001627	Gram-negative bacterial TonB protein C-terminal; Region: TonB_C; pfam03544
1094466001628	PBP superfamily domain; Region: PBP_like_2; pfam12849
1094466001629	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
1094466001630	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466001631	TPR motif; other site
1094466001632	binding surface
1094466001633	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1094466001634	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1094466001635	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466001636	S-adenosylmethionine binding site [chemical binding]; other site
1094466001637	Putative zinc- or iron-chelating domain; Region: CxxCxxCC; pfam03692
1094466001638	Protein of unknown function (DUF1343); Region: DUF1343; pfam07075
1094466001639	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1094466001640	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1094466001641	FtsX-like permease family; Region: FtsX; pfam02687
1094466001642	Ferritin-like domain; Region: Ferritin; pfam00210
1094466001643	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1094466001644	dimerization interface [polypeptide binding]; other site
1094466001645	DPS ferroxidase diiron center [ion binding]; other site
1094466001646	ion pore; other site
1094466001647	ZIP Zinc transporter; Region: Zip; cl00437
1094466001648	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466001649	S-adenosylmethionine binding site [chemical binding]; other site
1094466001650	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
1094466001651	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1094466001652	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466001653	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
1094466001654	TRAM domain; Region: TRAM; cl01282
1094466001655	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466001656	S-adenosylmethionine binding site [chemical binding]; other site
1094466001657	Protein of unknown function (DUF1697); Region: DUF1697; pfam08002
1094466001658	Protein of unknown function (DUF1003); Region: DUF1003; pfam06210
1094466001659	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1094466001660	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
1094466001661	inhibitor-cofactor binding pocket; inhibition site
1094466001662	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466001663	catalytic residue [active]
1094466001664	Glu/Leu/Phe/Val dehydrogenase, dimerization domain; Region: ELFV_dehydrog_N; pfam02812
1094466001665	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
1094466001666	NAD(P) binding pocket [chemical binding]; other site
1094466001667	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
1094466001668	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1094466001669	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
1094466001670	FAD binding site [chemical binding]; other site
1094466001671	homotetramer interface [polypeptide binding]; other site
1094466001672	substrate binding pocket [chemical binding]; other site
1094466001673	catalytic base [active]
1094466001674	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1094466001675	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1094466001676	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1094466001677	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1094466001678	gliding motility-associated lipoprotein GldJ; Region: GldJ; TIGR03524
1094466001679	Sulfatase-modifying factor enzyme 1; Region: FGE-sulfatase; cl19582
1094466001680	Peptidase C25 family N-terminal domain, found in Arg-gingipain (Rgp), Lys-gingipain (Kgp) and related proteins; Region: Peptidase_C25_N; cd02258
1094466001681	active site
1094466001682	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1094466001683	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
1094466001684	cytidine deaminase, homotetrameric; Region: cyt_deam_tetra; TIGR01354
1094466001685	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1094466001686	active site
1094466001687	catalytic motif [active]
1094466001688	Zn binding site [ion binding]; other site
1094466001689	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1094466001690	tetramer interface [polypeptide binding]; other site
1094466001691	TPP-binding site [chemical binding]; other site
1094466001692	heterodimer interface [polypeptide binding]; other site
1094466001693	phosphorylation loop region [posttranslational modification]
1094466001694	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1094466001695	E3 interaction surface; other site
1094466001696	lipoyl attachment site [posttranslational modification]; other site
1094466001697	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
1094466001698	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1094466001699	E3 interaction surface; other site
1094466001700	lipoyl attachment site [posttranslational modification]; other site
1094466001701	e3 binding domain; Region: E3_binding; pfam02817
1094466001702	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1094466001703	M28 Zn-Peptidase IAP aminopeptidase may contain PA domain insert; Region: M28_like_5; cd08021
1094466001704	Predicted aminopeptidases [General function prediction only]; Region: Iap; COG2234
1094466001705	metal binding site [ion binding]; metal-binding site
1094466001706	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1094466001707	classical (c) SDRs; Region: SDR_c; cd05233
1094466001708	NAD(P) binding site [chemical binding]; other site
1094466001709	active site
1094466001710	SprT-like family; Region: SprT-like; pfam10263
1094466001711	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
1094466001712	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1094466001713	Substrate binding site; other site
1094466001714	Cupin domain; Region: Cupin_2; cl17218
1094466001715	YtxH-like protein; Region: YtxH; cl02079
1094466001716	Amidinotransferase; Region: Amidinotransf; cl19186
1094466001717	Amidinotransferase; Region: Amidinotransf; cl19186
1094466001718	MarC family integral membrane protein; Region: MarC; cl00919
1094466001719	CoA binding domain; Region: CoA_binding_2; pfam13380
1094466001720	Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain; Region: SLC5sbd_NIS-like; cd10326
1094466001721	Na binding site [ion binding]; other site
1094466001722	recombination protein RecR; Reviewed; Region: recR; PRK00076
1094466001723	RecR protein; Region: RecR; pfam02132
1094466001724	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1094466001725	putative active site [active]
1094466001726	putative metal-binding site [ion binding]; other site
1094466001727	tetramer interface [polypeptide binding]; other site
1094466001728	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1094466001729	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
1094466001730	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1094466001731	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
1094466001732	AAA domain; Region: AAA_31; pfam13614
1094466001733	Vi polysaccharide biosynthesis protein TviC; Provisional; Region: PRK15181
1094466001734	UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs; Region: UDP_AE_SDR_e; cd05256
1094466001735	NAD binding site [chemical binding]; other site
1094466001736	substrate binding site [chemical binding]; other site
1094466001737	homodimer interface [polypeptide binding]; other site
1094466001738	active site
1094466001739	probable UDP-glucose 6-dehydrogenase; Region: PLN02353
1094466001740	UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; Region: UDPG_MGDP_dh_N; pfam03721
1094466001741	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1094466001742	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1094466001743	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
1094466001744	UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; Region: UDPG_MGDP_dh_N; pfam03721
1094466001745	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1094466001746	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1094466001747	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1094466001748	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1094466001749	Methyltransferase FkbM domain; Region: Methyltransf_21; cl17387
1094466001750	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1094466001751	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1094466001752	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1094466001753	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1094466001754	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1094466001755	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1094466001756	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1094466001757	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
1094466001758	NAD(P) binding site [chemical binding]; other site
1094466001759	active site
1094466001760	dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfbC; COG1898
1094466001761	GxxExxY protein; Region: GxxExxY; TIGR04256
1094466001762	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1094466001763	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1094466001764	active site
1094466001765	homodimer interface [polypeptide binding]; other site
1094466001766	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
1094466001767	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1094466001768	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
1094466001769	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
1094466001770	putative trimer interface [polypeptide binding]; other site
1094466001771	putative CoA binding site [chemical binding]; other site
1094466001772	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1094466001773	inhibitor-cofactor binding pocket; inhibition site
1094466001774	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466001775	catalytic residue [active]
1094466001776	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
1094466001777	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
1094466001778	NAD(P) binding site [chemical binding]; other site
1094466001779	homodimer interface [polypeptide binding]; other site
1094466001780	substrate binding site [chemical binding]; other site
1094466001781	active site
1094466001782	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1094466001783	SLBB domain; Region: SLBB; pfam10531
1094466001784	exopolysaccharide transport protein family; Region: eps_transp_fam; TIGR01005
1094466001785	Chain length determinant protein; Region: Wzz; pfam02706
1094466001786	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1094466001787	AAA domain; Region: AAA_31; pfam13614
1094466001788	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
1094466001789	PHP domain; Region: PHP; pfam02811
1094466001790	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1094466001791	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1094466001792	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466001793	Walker A/P-loop; other site
1094466001794	ATP binding site [chemical binding]; other site
1094466001795	Q-loop/lid; other site
1094466001796	ABC transporter signature motif; other site
1094466001797	Walker B; other site
1094466001798	D-loop; other site
1094466001799	H-loop/switch region; other site
1094466001800	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1094466001801	active site
1094466001802	N-terminal domain of galactosyltransferase; Region: Glyco_transf_7C; pfam02709
1094466001803	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1094466001804	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl19158
1094466001805	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
1094466001806	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
1094466001807	NeuB family; Region: NeuB; pfam03102
1094466001808	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1094466001809	NeuB binding interface [polypeptide binding]; other site
1094466001810	putative substrate binding site [chemical binding]; other site
1094466001811	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; Region: NeuC_NnaA; TIGR03568
1094466001812	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1094466001813	active site
1094466001814	homodimer interface [polypeptide binding]; other site
1094466001815	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
1094466001816	ligand binding site; other site
1094466001817	tetramer interface; other site
1094466001818	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1094466001819	active site
1094466001820	asparagine synthase (glutamine-hydrolyzing); Region: asn_synth_AEB; TIGR01536
1094466001821	dimer interface [polypeptide binding]; other site
1094466001822	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1094466001823	Ligand Binding Site [chemical binding]; other site
1094466001824	Molecular Tunnel; other site
1094466001825	diacylglycerol glucosyltransferase; Provisional; Region: PRK13609
1094466001826	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1094466001827	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
1094466001828	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1094466001829	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1094466001830	Ligand binding site; other site
1094466001831	Putative Catalytic site; other site
1094466001832	DXD motif; other site
1094466001833	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
1094466001834	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
1094466001835	putative trimer interface [polypeptide binding]; other site
1094466001836	putative CoA binding site [chemical binding]; other site
1094466001837	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1094466001838	inhibitor-cofactor binding pocket; inhibition site
1094466001839	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466001840	catalytic residue [active]
1094466001841	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1094466001842	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1094466001843	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1094466001844	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1094466001845	active site
1094466001846	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
1094466001847	Exostosin family; Region: Exostosin; pfam03016
1094466001848	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1094466001849	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466001850	S-adenosylmethionine binding site [chemical binding]; other site
1094466001851	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1094466001852	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1094466001853	active site
1094466001854	N-terminal domain of galactosyltransferase; Region: Glyco_transf_7C; cl17476
1094466001855	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1094466001856	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1094466001857	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1094466001858	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1094466001859	O-Antigen ligase; Region: Wzy_C; pfam04932
1094466001860	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1094466001861	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1094466001862	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
1094466001863	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1094466001864	Domain of unknown function (DUF4105); Region: DUF4105; pfam13387
1094466001865	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
1094466001866	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1094466001867	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
1094466001868	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
1094466001869	active site
1094466001870	Protein of unknown function (DUF1648); Region: DUF1648; cl19856
1094466001871	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
1094466001872	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1094466001873	Walker A/P-loop; other site
1094466001874	ATP binding site [chemical binding]; other site
1094466001875	Q-loop/lid; other site
1094466001876	ABC transporter signature motif; other site
1094466001877	Walker B; other site
1094466001878	D-loop; other site
1094466001879	H-loop/switch region; other site
1094466001880	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1094466001881	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
1094466001882	KpsF/GutQ family protein; Region: kpsF; TIGR00393
1094466001883	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1094466001884	putative active site [active]
1094466001885	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1094466001886	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
1094466001887	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1094466001888	ATP binding site [chemical binding]; other site
1094466001889	putative Mg++ binding site [ion binding]; other site
1094466001890	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1094466001891	nucleotide binding region [chemical binding]; other site
1094466001892	ATP-binding site [chemical binding]; other site
1094466001893	RQC domain; Region: RQC; pfam09382
1094466001894	HRDC domain; Region: HRDC; pfam00570
1094466001895	Helix-turn-helix domain; Region: HTH_40; pfam14493
1094466001896	Fasciclin domain; Region: Fasciclin; pfam02469
1094466001897	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
1094466001898	Fasciclin domain; Region: Fasciclin; pfam02469
1094466001899	Protein of unknown function (Porph_ging); Region: Porph_ging; cl09903
1094466001900	Peptide-N-glycosidase F, N terminal; Region: N-glycanase_N; pfam09112
1094466001901	Peptide-N-glycosidase F, C terminal; Region: N-glycanase_C; pfam09113
1094466001902	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1094466001903	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1094466001904	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1094466001905	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1094466001906	dimerization interface [polypeptide binding]; other site
1094466001907	Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649
1094466001908	putative SAM binding site [chemical binding]; other site
1094466001909	homodimer interface [polypeptide binding]; other site
1094466001910	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1094466001911	active site
1094466001912	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1094466001913	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1094466001914	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466001915	Walker A motif; other site
1094466001916	ATP binding site [chemical binding]; other site
1094466001917	Walker B motif; other site
1094466001918	arginine finger; other site
1094466001919	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1094466001920	DnaA box-binding interface [nucleotide binding]; other site
1094466001921	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1094466001922	active site
1094466001923	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1094466001924	uncharacterized protein, YigZ family; Region: IMPACT_YIGZ; TIGR00257
1094466001925	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
1094466001926	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1094466001927	motif II; other site
1094466001928	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1094466001929	catalytic motif [active]
1094466001930	Zn binding site [ion binding]; other site
1094466001931	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
1094466001932	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1094466001933	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1094466001934	Coenzyme A binding pocket [chemical binding]; other site
1094466001935	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1094466001936	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466001937	S-adenosylmethionine binding site [chemical binding]; other site
1094466001938	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1094466001939	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1094466001940	FtsX-like permease family; Region: FtsX; pfam02687
1094466001941	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1094466001942	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1094466001943	dimer interface [polypeptide binding]; other site
1094466001944	motif 1; other site
1094466001945	active site
1094466001946	motif 2; other site
1094466001947	motif 3; other site
1094466001948	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1094466001949	anticodon binding site; other site
1094466001950	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1094466001951	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1094466001952	cation binding site [ion binding]; other site
1094466001953	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466001954	Walker A/P-loop; other site
1094466001955	ATP binding site [chemical binding]; other site
1094466001956	Q-loop/lid; other site
1094466001957	ABC transporter signature motif; other site
1094466001958	Walker B; other site
1094466001959	D-loop; other site
1094466001960	FtsX-like permease family; Region: FtsX; pfam02687
1094466001961	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1094466001962	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1094466001963	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1094466001964	homodimer interface [polypeptide binding]; other site
1094466001965	metal binding site [ion binding]; metal-binding site
1094466001966	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1094466001967	homodimer interface [polypeptide binding]; other site
1094466001968	active site
1094466001969	putative chemical substrate binding site [chemical binding]; other site
1094466001970	metal binding site [ion binding]; metal-binding site
1094466001971	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1094466001972	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
1094466001973	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1094466001974	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1094466001975	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
1094466001976	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1094466001977	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1094466001978	putative active site [active]
1094466001979	metal binding site [ion binding]; metal-binding site
1094466001980	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1094466001981	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1094466001982	quinone interaction residues [chemical binding]; other site
1094466001983	active site
1094466001984	catalytic residues [active]
1094466001985	FMN binding site [chemical binding]; other site
1094466001986	substrate binding site [chemical binding]; other site
1094466001987	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1094466001988	active site
1094466001989	dimerization interface [polypeptide binding]; other site
1094466001990	Predicted membrane protein [Function unknown]; Region: COG2860
1094466001991	UPF0126 domain; Region: UPF0126; pfam03458
1094466001992	UPF0126 domain; Region: UPF0126; pfam03458
1094466001993	helicase 45; Provisional; Region: PTZ00424
1094466001994	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1094466001995	ATP binding site [chemical binding]; other site
1094466001996	Mg++ binding site [ion binding]; other site
1094466001997	motif III; other site
1094466001998	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1094466001999	nucleotide binding region [chemical binding]; other site
1094466002000	ATP-binding site [chemical binding]; other site
1094466002001	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
1094466002002	RNA binding site [nucleotide binding]; other site
1094466002003	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466002004	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1094466002005	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1094466002006	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1094466002007	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
1094466002008	DNA binding residues [nucleotide binding]
1094466002009	putative anti-sigmaE protein; Provisional; Region: PRK13920
1094466002010	Anti-sigma-K factor rskA; Region: RskA; pfam10099
1094466002011	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1094466002012	NAD+ binding site [chemical binding]; other site
1094466002013	substrate binding site [chemical binding]; other site
1094466002014	Zn binding site [ion binding]; other site
1094466002015	adenylosuccinate lyase; Provisional; Region: PRK09285
1094466002016	Lyase class I_like superfamily: contains the lyase class I family, histidine ammonia-lyase and phenylalanine ammonia-lyase, which catalyze similar beta-elimination reactions; Region: Lyase_I_like; cl00013
1094466002017	tetramer interface [polypeptide binding]; other site
1094466002018	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
1094466002019	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1094466002020	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1094466002021	active site
1094466002022	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1094466002023	3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain; Region: DRE_TIM_HMGL; cd07938
1094466002024	active site
1094466002025	catalytic residues [active]
1094466002026	metal binding site [ion binding]; metal-binding site
1094466002027	8-amino-7-oxononanoate synthase; Region: bioF; TIGR00858
1094466002028	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
1094466002029	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1094466002030	catalytic residue [active]
1094466002031	bifunctional preprotein translocase subunit SecD/SecF; Reviewed; Region: PRK13024
1094466002032	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1094466002033	Protein export membrane protein; Region: SecD_SecF; pfam02355
1094466002034	Domain of unknown function (DUF4268); Region: DUF4268; pfam14088
1094466002035	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1094466002036	putative active site [active]
1094466002037	putative CoA binding site [chemical binding]; other site
1094466002038	nudix motif; other site
1094466002039	metal binding site [ion binding]; metal-binding site
1094466002040	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1094466002041	putative acyl-acceptor binding pocket; other site
1094466002042	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
1094466002043	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1094466002044	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1094466002045	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1094466002046	DNA binding residues [nucleotide binding]
1094466002047	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1094466002048	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1094466002049	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1094466002050	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
1094466002051	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1094466002052	dimerization interface [polypeptide binding]; other site
1094466002053	active site
1094466002054	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
1094466002055	Chalcone-flavanone isomerase; Region: Chalcone; cl03589
1094466002056	SnoaL-like domain; Region: SnoaL_2; pfam12680
1094466002057	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1094466002058	oligomer interface [polypeptide binding]; other site
1094466002059	active site
1094466002060	metal binding site [ion binding]; metal-binding site
1094466002061	Domain of unknown function (DUF4294); Region: DUF4294; pfam14127
1094466002062	Protein of unknown function (DUF3276); Region: DUF3276; pfam11680
1094466002063	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1094466002064	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1094466002065	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466002066	Walker A/P-loop; other site
1094466002067	ATP binding site [chemical binding]; other site
1094466002068	Q-loop/lid; other site
1094466002069	ABC transporter signature motif; other site
1094466002070	Walker B; other site
1094466002071	D-loop; other site
1094466002072	H-loop/switch region; other site
1094466002073	Glu/Leu/Phe/Val dehydrogenase, dimerization domain; Region: ELFV_dehydrog_N; pfam02812
1094466002074	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Region: ELFV_dehydrog; pfam00208
1094466002075	NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Region: NAD_bind_Leu_Phe_Val_DH; cd01075
1094466002076	NAD binding site [chemical binding]; other site
1094466002077	Phe binding site; other site
1094466002078	transcription antitermination factor NusB; Region: nusB; TIGR01951
1094466002079	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
1094466002080	Preprotein translocase subunit; Region: YajC; pfam02699
1094466002081	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1094466002082	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466002083	active site
1094466002084	phosphorylation site [posttranslational modification]
1094466002085	intermolecular recognition site; other site
1094466002086	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1094466002087	peptidase T-like protein; Region: PepT-like; TIGR01883
1094466002088	metal binding site [ion binding]; metal-binding site
1094466002089	dimer interface [polypeptide binding]; other site
1094466002090	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1094466002091	active site
1094466002092	catalytic residues [active]
1094466002093	metal binding site [ion binding]; metal-binding site
1094466002094	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1094466002095	GldH lipoprotein; Region: GldH_lipo; cl11905
1094466002096	Dienelactone hydrolase family; Region: DLH; pfam01738
1094466002097	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1094466002098	Haemolytic domain; Region: Haemolytic; pfam01809
1094466002099	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1094466002100	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1094466002101	active site
1094466002102	HIGH motif; other site
1094466002103	KMSKS motif; other site
1094466002104	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1094466002105	GTP cyclohydrolase I; Region: GTP_cyclohydroI; pfam01227
1094466002106	active site
1094466002107	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1094466002108	CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; Region: CUB; cl00049
1094466002109	heterodimerization interface [polypeptide binding]; other site
1094466002110	Proprotein convertase P-domain; Region: P_proprotein; pfam01483
1094466002111	Herpes virus major outer envelope glycoprotein (BLLF1); Region: Herpes_BLLF1; pfam05109
1094466002112	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1094466002113	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1094466002114	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1094466002115	active site
1094466002116	acetyl-CoA acetyltransferase; Provisional; Region: PRK09052
1094466002117	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1094466002118	dimer interface [polypeptide binding]; other site
1094466002119	active site
1094466002120	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
1094466002121	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1094466002122	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1094466002123	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1094466002124	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
1094466002125	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1094466002126	substrate binding site [chemical binding]; other site
1094466002127	oxyanion hole (OAH) forming residues; other site
1094466002128	trimer interface [polypeptide binding]; other site
1094466002129	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1094466002130	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
1094466002131	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
1094466002132	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
1094466002133	acyl-activating enzyme (AAE) consensus motif; other site
1094466002134	putative AMP binding site [chemical binding]; other site
1094466002135	putative active site [active]
1094466002136	putative CoA binding site [chemical binding]; other site
1094466002137	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1094466002138	Sulfatase; Region: Sulfatase; pfam00884
1094466002139	Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; Region: DSPc; cl00053
1094466002140	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1094466002141	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1094466002142	substrate binding site [chemical binding]; other site
1094466002143	dimer interface [polypeptide binding]; other site
1094466002144	catalytic triad [active]
1094466002145	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1094466002146	catalytic residues [active]
1094466002147	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1094466002148	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
1094466002149	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
1094466002150	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1094466002151	Dihydropteroate synthase and related enzymes [Coenzyme metabolism]; Region: FolP; COG0294
1094466002152	substrate binding pocket [chemical binding]; other site
1094466002153	dimer interface [polypeptide binding]; other site
1094466002154	inhibitor binding site; inhibition site
1094466002155	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
1094466002156	hypothetical protein; Provisional; Region: PRK12378
1094466002157	Protein of unknown function (DUF2752); Region: DUF2752; pfam10825
1094466002158	TM2 domain; Region: TM2; pfam05154
1094466002159	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1094466002160	Aminomethyltransferase folate-binding domain; Region: GCV_T; pfam01571
1094466002161	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1094466002162	Aromatic amino acid lyase; Region: Lyase_aromatic; pfam00221
1094466002163	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1094466002164	active sites [active]
1094466002165	tetramer interface [polypeptide binding]; other site
1094466002166	Protein of unknown function (DUF1304); Region: DUF1304; pfam06993
1094466002167	gliding motility-associated protein GldL; Region: GldL_gliding; TIGR03513
1094466002168	Predicted membrane protein [Function unknown]; Region: COG2323
1094466002169	Uncharacterized protein conserved in archaea [Posttranslational modification, protein turnover, chaperones]; Region: COG4067
1094466002170	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
1094466002171	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1094466002172	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
1094466002173	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1094466002174	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1094466002175	Vps16, N-terminal region; Region: Vps16_N; pfam04841
1094466002176	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
1094466002177	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1094466002178	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1094466002179	putative DNA binding site [nucleotide binding]; other site
1094466002180	putative Zn2+ binding site [ion binding]; other site
1094466002181	AsnC family; Region: AsnC_trans_reg; pfam01037
1094466002182	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
1094466002183	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1094466002184	catalytic residue [active]
1094466002185	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
1094466002186	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1094466002187	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1094466002188	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1094466002189	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1094466002190	active site
1094466002191	imidazolonepropionase; Validated; Region: PRK09356
1094466002192	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1094466002193	active site
1094466002194	Thermotoga maritima CorA_like subfamily; Region: TmCorA-like_1; cd12828
1094466002195	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
1094466002196	oligomer interface [polypeptide binding]; other site
1094466002197	metal binding site [ion binding]; metal-binding site
1094466002198	metal binding site [ion binding]; metal-binding site
1094466002199	Cl binding site [ion binding]; other site
1094466002200	aspartate ring; other site
1094466002201	basic sphincter; other site
1094466002202	putative hydrophobic gate; other site
1094466002203	periplasmic entrance; other site
1094466002204	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1094466002205	putative DNA binding site [nucleotide binding]; other site
1094466002206	dimerization interface [polypeptide binding]; other site
1094466002207	putative Zn2+ binding site [ion binding]; other site
1094466002208	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466002209	S-adenosylmethionine binding site [chemical binding]; other site
1094466002210	Low molecular weight phosphatase family; Region: LMWPc; cl00105
1094466002211	arsenical-resistance protein; Region: acr3; TIGR00832
1094466002212	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466002213	binding surface
1094466002214	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1094466002215	TPR motif; other site
1094466002216	DNA gyrase subunit A; Validated; Region: PRK05560
1094466002217	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1094466002218	CAP-like domain; other site
1094466002219	active site
1094466002220	primary dimer interface [polypeptide binding]; other site
1094466002221	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1094466002222	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1094466002223	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1094466002224	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1094466002225	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1094466002226	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1094466002227	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1094466002228	Clp amino terminal domain; Region: Clp_N; pfam02861
1094466002229	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466002230	Walker A motif; other site
1094466002231	ATP binding site [chemical binding]; other site
1094466002232	Walker B motif; other site
1094466002233	arginine finger; other site
1094466002234	UvrB/uvrC motif; Region: UVR; pfam02151
1094466002235	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466002236	Walker A motif; other site
1094466002237	ATP binding site [chemical binding]; other site
1094466002238	Walker B motif; other site
1094466002239	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1094466002240	Domain of unknown function (DUF4349); Region: DUF4349; pfam14257
1094466002241	cationic amino acid transport permease; Region: 2A0303; TIGR00906
1094466002242	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
1094466002243	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1094466002244	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1094466002245	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1094466002246	dimer interface [polypeptide binding]; other site
1094466002247	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1094466002248	catalytic triad [active]
1094466002249	peroxidatic and resolving cysteines [active]
1094466002250	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1094466002251	catalytic residues [active]
1094466002252	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
1094466002253	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
1094466002254	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1094466002255	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
1094466002256	PspC domain; Region: PspC; pfam04024
1094466002257	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
1094466002258	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1094466002259	dimerization interface [polypeptide binding]; other site
1094466002260	putative Zn2+ binding site [ion binding]; other site
1094466002261	putative DNA binding site [nucleotide binding]; other site
1094466002262	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
1094466002263	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1094466002264	TIGR01777 family protein; Region: yfcH
1094466002265	NAD(P) binding site [chemical binding]; other site
1094466002266	active site
1094466002267	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1094466002268	dimer interface [polypeptide binding]; other site
1094466002269	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1094466002270	chaperone protein DnaJ; Provisional; Region: PRK14289
1094466002271	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1094466002272	HSP70 interaction site [polypeptide binding]; other site
1094466002273	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1094466002274	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1094466002275	dimer interface [polypeptide binding]; other site
1094466002276	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
1094466002277	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466002278	Walker A/P-loop; other site
1094466002279	ATP binding site [chemical binding]; other site
1094466002280	Q-loop/lid; other site
1094466002281	ABC transporter signature motif; other site
1094466002282	Walker B; other site
1094466002283	D-loop; other site
1094466002284	H-loop/switch region; other site
1094466002285	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
1094466002286	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1094466002287	Response regulator with putative antiterminator output domain [Signal transduction mechanisms]; Region: AmiR; COG3707
1094466002288	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466002289	active site
1094466002290	phosphorylation site [posttranslational modification]
1094466002291	intermolecular recognition site; other site
1094466002292	dimerization interface [polypeptide binding]; other site
1094466002293	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466002294	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1094466002295	Walker A motif; other site
1094466002296	ATP binding site [chemical binding]; other site
1094466002297	Walker B motif; other site
1094466002298	arginine finger; other site
1094466002299	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1094466002300	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1094466002301	ATP binding site [chemical binding]; other site
1094466002302	putative Mg++ binding site [ion binding]; other site
1094466002303	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1094466002304	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1094466002305	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466002306	ABC transporter signature motif; other site
1094466002307	Walker B; other site
1094466002308	D-loop; other site
1094466002309	H-loop/switch region; other site
1094466002310	ABC transporter; Region: ABC_tran_2; pfam12848
1094466002311	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1094466002312	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1094466002313	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466002314	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466002315	binding surface
1094466002316	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466002317	TPR motif; other site
1094466002318	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466002319	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1094466002320	dimer interface [polypeptide binding]; other site
1094466002321	phosphorylation site [posttranslational modification]
1094466002322	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466002323	ATP binding site [chemical binding]; other site
1094466002324	Mg2+ binding site [ion binding]; other site
1094466002325	G-X-G motif; other site
1094466002326	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466002327	active site
1094466002328	phosphorylation site [posttranslational modification]
1094466002329	intermolecular recognition site; other site
1094466002330	dimerization interface [polypeptide binding]; other site
1094466002331	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466002332	von Willebrand factor; Region: vWF_A; pfam12450
1094466002333	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
1094466002334	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
1094466002335	metal ion-dependent adhesion site (MIDAS); other site
1094466002336	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
1094466002337	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
1094466002338	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1094466002339	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1094466002340	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1094466002341	DNA binding residues [nucleotide binding]
1094466002342	Polyphosphate kinase 2 (PPK2); Region: PPK2; cl11971
1094466002343	Protein of unknown function (DUF3570); Region: DUF3570; pfam12094
1094466002344	YedD-like protein; Region: YedD; cl08117
1094466002345	ApbE family; Region: ApbE; pfam02424
1094466002346	Thioredoxin-like; Region: Thioredoxin_7; pfam13899
1094466002347	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1094466002348	Thiamine pyrophosphokinase; Region: TPK; cd07995
1094466002349	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
1094466002350	active site
1094466002351	dimerization interface [polypeptide binding]; other site
1094466002352	thiamine binding site [chemical binding]; other site
1094466002353	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
1094466002354	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466002355	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466002356	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1094466002357	Monomeric isocitrate dehydrogenase; Region: IDH; cl15383
1094466002358	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1094466002359	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1094466002360	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1094466002361	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1094466002362	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1094466002363	EamA-like transporter family; Region: EamA; pfam00892
1094466002364	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1094466002365	replicative DNA helicase; Region: DnaB; TIGR00665
1094466002366	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1094466002367	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1094466002368	Walker A motif; other site
1094466002369	ATP binding site [chemical binding]; other site
1094466002370	Walker B motif; other site
1094466002371	DNA binding loops [nucleotide binding]
1094466002372	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1094466002373	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466002374	active site
1094466002375	phosphorylation site [posttranslational modification]
1094466002376	intermolecular recognition site; other site
1094466002377	dimerization interface [polypeptide binding]; other site
1094466002378	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1094466002379	DNA binding residues [nucleotide binding]
1094466002380	dimerization interface [polypeptide binding]; other site
1094466002381	glutaminase; Provisional; Region: PRK00971
1094466002382	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466002383	S-adenosylmethionine binding site [chemical binding]; other site
1094466002384	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1094466002385	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1094466002386	active site
1094466002387	motif I; other site
1094466002388	motif II; other site
1094466002389	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
1094466002390	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1094466002391	23S rRNA binding site [nucleotide binding]; other site
1094466002392	L21 binding site [polypeptide binding]; other site
1094466002393	L13 binding site [polypeptide binding]; other site
1094466002394	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1094466002395	translation initiation factor IF-3; Region: infC; TIGR00168
1094466002396	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1094466002397	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1094466002398	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1094466002399	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1094466002400	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1094466002401	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1094466002402	active site
1094466002403	dimer interface [polypeptide binding]; other site
1094466002404	motif 1; other site
1094466002405	motif 2; other site
1094466002406	motif 3; other site
1094466002407	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1094466002408	anticodon binding site; other site
1094466002409	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1094466002410	Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarB; COG0458
1094466002411	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1094466002412	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1094466002413	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; smart01096
1094466002414	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1094466002415	Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarB; COG0458
1094466002416	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1094466002417	Protein of unknown function (Porph_ging); Region: Porph_ging; cl09903
1094466002418	Domain of unknown function (DUF4412); Region: DUF4412; pfam14371
1094466002419	Inward rectifier potassium channel; Region: IRK; pfam01007
1094466002420	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1094466002421	Protein of unknown function (DUF3186); Region: DUF3186; pfam11382
1094466002422	RmuC family; Region: RmuC; pfam02646
1094466002423	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1094466002424	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1094466002425	active site
1094466002426	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
1094466002427	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1094466002428	Walker A/P-loop; other site
1094466002429	ATP binding site [chemical binding]; other site
1094466002430	Q-loop/lid; other site
1094466002431	ABC transporter signature motif; other site
1094466002432	Walker B; other site
1094466002433	D-loop; other site
1094466002434	H-loop/switch region; other site
1094466002435	GxxExxY protein; Region: GxxExxY; TIGR04256
1094466002436	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1094466002437	ABC-ATPase subunit  interface; other site
1094466002438	dimer interface [polypeptide binding]; other site
1094466002439	putative PBP binding regions; other site
1094466002440	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1094466002441	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1094466002442	intersubunit interface [polypeptide binding]; other site
1094466002443	Cysteine-rich CWC; Region: Cys_rich_CWC; pfam14375
1094466002444	Cobinamide kinase / cobinamide phosphate guanyltransferase; Region: CobU; pfam02283
1094466002445	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_IV; cd01994
1094466002446	Ligand Binding Site [chemical binding]; other site
1094466002447	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
1094466002448	FMN binding site [chemical binding]; other site
1094466002449	dimer interface [polypeptide binding]; other site
1094466002450	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1094466002451	putative dimer interface [polypeptide binding]; other site
1094466002452	active site pocket [active]
1094466002453	putative cataytic base [active]
1094466002454	cobalamin synthase; Reviewed; Region: cobS; PRK00235
1094466002455	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1094466002456	catalytic core [active]
1094466002457	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
1094466002458	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1094466002459	N-terminal plug; other site
1094466002460	ligand-binding site [chemical binding]; other site
1094466002461	Domain of unknown function (DUF4252); Region: DUF4252; pfam14060
1094466002462	Domain of unknown function (DUF4252); Region: DUF4252; pfam14060
1094466002463	beta-carotene hydroxylase; Region: PLN02601
1094466002464	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
1094466002465	active site lid residues [active]
1094466002466	substrate binding pocket [chemical binding]; other site
1094466002467	catalytic residues [active]
1094466002468	substrate-Mg2+ binding site; other site
1094466002469	aspartate-rich region 1; other site
1094466002470	aspartate-rich region 2; other site
1094466002471	phytoene desaturase; Region: crtI_fam; TIGR02734
1094466002472	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1094466002473	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1094466002474	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1094466002475	DNA binding residues [nucleotide binding]
1094466002476	Hg(II)-responsive transcriptional regulator; Region: MerR; TIGR02051
1094466002477	B12 binding domain; Region: B12-binding_2; pfam02607
1094466002478	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
1094466002479	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1094466002480	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1094466002481	ADP binding site [chemical binding]; other site
1094466002482	magnesium binding site [ion binding]; other site
1094466002483	putative shikimate binding site; other site
1094466002484	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1094466002485	active site
1094466002486	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466002487	S-adenosylmethionine binding site [chemical binding]; other site
1094466002488	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1094466002489	RNA binding surface [nucleotide binding]; other site
1094466002490	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
1094466002491	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1094466002492	Tetrahydrodipicolinate N-succinyltransferase N-terminal; Region: THDPS_N_2; pfam14805
1094466002493	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1094466002494	trimer interface [polypeptide binding]; other site
1094466002495	active site
1094466002496	substrate binding site [chemical binding]; other site
1094466002497	CoA binding site [chemical binding]; other site
1094466002498	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1094466002499	Sulfatase; Region: Sulfatase; cl19157
1094466002500	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1094466002501	putative metal binding site; other site
1094466002502	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1094466002503	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1094466002504	N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase; Region: GT2_Chondriotin_Pol_N; cd06420
1094466002505	Substrate binding site; other site
1094466002506	metal-binding site
1094466002507	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1094466002508	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1094466002509	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1094466002510	metal-binding site
1094466002511	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1094466002512	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1094466002513	NADP binding site [chemical binding]; other site
1094466002514	active site
1094466002515	putative substrate binding site [chemical binding]; other site
1094466002516	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1094466002517	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1094466002518	NADP-binding site; other site
1094466002519	homotetramer interface [polypeptide binding]; other site
1094466002520	substrate binding site [chemical binding]; other site
1094466002521	homodimer interface [polypeptide binding]; other site
1094466002522	active site
1094466002523	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1094466002524	inhibitor-cofactor binding pocket; inhibition site
1094466002525	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466002526	catalytic residue [active]
1094466002527	WxcM-like, C-terminal; Region: FdtA; pfam05523
1094466002528	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1094466002529	active site
1094466002530	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1094466002531	active site
1094466002532	Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; cl19502
1094466002533	pseudaminic acid synthase; Region: PseI; TIGR03586
1094466002534	NeuB family; Region: NeuB; pfam03102
1094466002535	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1094466002536	NeuB binding interface [polypeptide binding]; other site
1094466002537	putative substrate binding site [chemical binding]; other site
1094466002538	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1094466002539	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1094466002540	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1094466002541	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1094466002542	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
1094466002543	ligand binding site; other site
1094466002544	tetramer interface; other site
1094466002545	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
1094466002546	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
1094466002547	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1094466002548	inhibitor-cofactor binding pocket; inhibition site
1094466002549	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466002550	catalytic residue [active]
1094466002551	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1094466002552	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1094466002553	tRNA adenylyltransferase; Region: tRNA_CCA_actino; TIGR02692
1094466002554	active site
1094466002555	NTP binding site [chemical binding]; other site
1094466002556	metal binding triad [ion binding]; metal-binding site
1094466002557	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1094466002558	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1094466002559	Zn2+ binding site [ion binding]; other site
1094466002560	Mg2+ binding site [ion binding]; other site
1094466002561	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
1094466002562	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
1094466002563	Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic...; Region: PRX_like1; cd02969
1094466002564	putative catalytic residue [active]
1094466002565	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1094466002566	catalytic residues [active]
1094466002567	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1094466002568	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466002569	active site
1094466002570	phosphorylation site [posttranslational modification]
1094466002571	intermolecular recognition site; other site
1094466002572	dimerization interface [polypeptide binding]; other site
1094466002573	LytTr DNA-binding domain; Region: LytTR; smart00850
1094466002574	2TM domain; Region: 2TM; pfam13239
1094466002575	2TM domain; Region: 2TM; pfam13239
1094466002576	2TM domain; Region: 2TM; pfam13239
1094466002577	Histidine kinase; Region: His_kinase; pfam06580
1094466002578	2TM domain; Region: 2TM; pfam13239
1094466002579	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466002580	Fic family protein [Function unknown]; Region: COG3177
1094466002581	Fic/DOC family; Region: Fic; pfam02661
1094466002582	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1094466002583	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1094466002584	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1094466002585	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1094466002586	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1094466002587	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1094466002588	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1094466002589	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1094466002590	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1094466002591	Domain of unknown function (DUF4325); Region: DUF4325; pfam14213
1094466002592	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1094466002593	Uncharacterized ACR, COG1993; Region: DUF190; cl00872
1094466002594	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1094466002595	HlyD family secretion protein; Region: HlyD_3; pfam13437
1094466002596	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1094466002597	Outer membrane efflux protein; Region: OEP; pfam02321
1094466002598	Outer membrane efflux protein; Region: OEP; pfam02321
1094466002599	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1094466002600	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1094466002601	dimerization interface [polypeptide binding]; other site
1094466002602	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1094466002603	dimer interface [polypeptide binding]; other site
1094466002604	phosphorylation site [posttranslational modification]
1094466002605	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466002606	ATP binding site [chemical binding]; other site
1094466002607	Mg2+ binding site [ion binding]; other site
1094466002608	G-X-G motif; other site
1094466002609	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1094466002610	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466002611	active site
1094466002612	phosphorylation site [posttranslational modification]
1094466002613	intermolecular recognition site; other site
1094466002614	dimerization interface [polypeptide binding]; other site
1094466002615	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1094466002616	DNA binding site [nucleotide binding]
1094466002617	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1094466002618	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1094466002619	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1094466002620	EamA-like transporter family; Region: EamA; cl17759
1094466002621	PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_4; cd03395
1094466002622	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1094466002623	active site
1094466002624	Uncharacterized ACR, COG1993; Region: DUF190; cl00872
1094466002625	ClC sycA-like chloride channel proteins. This ClC family presents in bacteria, where it facilitates acid resistance in acidic soil. Mutation of this gene (sycA) in Rhizobium tropici CIAT899 causes serious deficiencies in nodule development, nodulation...; Region: ClC_sycA_like; cd03682
1094466002626	putative Cl- selectivity filter; other site
1094466002627	putative pore gating glutamate residue; other site
1094466002628	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1094466002629	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1094466002630	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1094466002631	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
1094466002632	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1094466002633	active site
1094466002634	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1094466002635	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1094466002636	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1094466002637	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1094466002638	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1094466002639	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1094466002640	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1094466002641	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1094466002642	shikimate binding site; other site
1094466002643	NAD(P) binding site [chemical binding]; other site
1094466002644	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1094466002645	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466002646	binding surface
1094466002647	TPR motif; other site
1094466002648	Tetratricopeptide repeat; Region: TPR_19; pfam14559
1094466002649	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466002650	binding surface
1094466002651	TPR motif; other site
1094466002652	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
1094466002653	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466002654	binding surface
1094466002655	TPR motif; other site
1094466002656	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466002657	binding surface
1094466002658	TPR motif; other site
1094466002659	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
1094466002660	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1094466002661	inhibitor-cofactor binding pocket; inhibition site
1094466002662	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466002663	catalytic residue [active]
1094466002664	OstA-like protein; Region: OstA; cl00844
1094466002665	OstA-like protein; Region: OstA; cl00844
1094466002666	Leucine rich repeat; Region: LRR_8; pfam13855
1094466002667	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466002668	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1094466002669	GDP-binding site [chemical binding]; other site
1094466002670	ACT binding site; other site
1094466002671	IMP binding site; other site
1094466002672	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1094466002673	metal binding site 2 [ion binding]; metal-binding site
1094466002674	putative DNA binding helix; other site
1094466002675	metal binding site 1 [ion binding]; metal-binding site
1094466002676	dimer interface [polypeptide binding]; other site
1094466002677	structural Zn2+ binding site [ion binding]; other site
1094466002678	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1094466002679	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1094466002680	Zn2+ binding site [ion binding]; other site
1094466002681	Mg2+ binding site [ion binding]; other site
1094466002682	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1094466002683	synthetase active site [active]
1094466002684	NTP binding site [chemical binding]; other site
1094466002685	metal binding site [ion binding]; metal-binding site
1094466002686	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1094466002687	ACT domain; Region: ACT_4; pfam13291
1094466002688	Beta-lactamase; Region: Beta-lactamase; pfam00144
1094466002689	Domain of unknown function (DUF3471); Region: DUF3471; pfam11954
1094466002690	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1094466002691	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1094466002692	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1094466002693	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
1094466002694	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1094466002695	active site
1094466002696	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1094466002697	active site
1094466002698	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
1094466002699	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1094466002700	active site
1094466002701	CARDB; Region: CARDB; pfam07705
1094466002702	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
1094466002703	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
1094466002704	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1094466002705	conserved hypothetical integral membrane protein; Region: TIGR03766
1094466002706	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1094466002707	Ligand binding site; other site
1094466002708	Putative Catalytic site; other site
1094466002709	DXD motif; other site
1094466002710	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1094466002711	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1094466002712	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1094466002713	PYR/PP interface [polypeptide binding]; other site
1094466002714	dimer interface [polypeptide binding]; other site
1094466002715	TPP binding site [chemical binding]; other site
1094466002716	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1094466002717	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1094466002718	TPP-binding site [chemical binding]; other site
1094466002719	dimer interface [polypeptide binding]; other site
1094466002720	Putative lysophospholipase; Region: Hydrolase_4; cl19140
1094466002721	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1094466002722	Peptidase family M48; Region: Peptidase_M48; pfam01435
1094466002723	Vacuole effluxer Atg22 like; Region: ATG22; pfam11700
1094466002724	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1094466002725	ATP-dependent protease La (LON) domain; Region: LON; pfam02190
1094466002726	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466002727	Walker A motif; other site
1094466002728	ATP binding site [chemical binding]; other site
1094466002729	Walker B motif; other site
1094466002730	arginine finger; other site
1094466002731	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1094466002732	cytidylate kinase; Provisional; Region: cmk; PRK00023
1094466002733	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1094466002734	CMP-binding site; other site
1094466002735	The sites determining sugar specificity; other site
1094466002736	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1094466002737	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1094466002738	RNA binding site [nucleotide binding]; other site
1094466002739	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1094466002740	RNA binding site [nucleotide binding]; other site
1094466002741	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1094466002742	RNA binding site [nucleotide binding]; other site
1094466002743	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1094466002744	RNA binding site [nucleotide binding]; other site
1094466002745	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1094466002746	RNA binding site [nucleotide binding]; other site
1094466002747	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
1094466002748	RNA binding site [nucleotide binding]; other site
1094466002749	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
1094466002750	Fasciclin domain; Region: Fasciclin; pfam02469
1094466002751	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1094466002752	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1094466002753	putative tRNA-binding site [nucleotide binding]; other site
1094466002754	B3/4 domain; Region: B3_4; pfam03483
1094466002755	tRNA synthetase B5 domain; Region: B5; pfam03484
1094466002756	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1094466002757	dimer interface [polypeptide binding]; other site
1094466002758	motif 1; other site
1094466002759	motif 3; other site
1094466002760	motif 2; other site
1094466002761	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1094466002762	K+ potassium transporter; Region: K_trans; pfam02705
1094466002763	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II and Staphylococcus aureus AldA1 (SACOL0154)-like; Region: ALDH_ACDHII_AcoD-like; cd07559
1094466002764	NAD(P) binding site [chemical binding]; other site
1094466002765	catalytic residues [active]
1094466002766	Protein of unknown function (DUF779); Region: DUF779; cl01432
1094466002767	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1094466002768	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1094466002769	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1094466002770	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1094466002771	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
1094466002772	Putative lysophospholipase; Region: Hydrolase_4; cl19140
1094466002773	Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; pfam01062
1094466002774	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1094466002775	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1094466002776	generic binding surface II; other site
1094466002777	ssDNA binding site; other site
1094466002778	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1094466002779	ATP binding site [chemical binding]; other site
1094466002780	putative Mg++ binding site [ion binding]; other site
1094466002781	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
1094466002782	putative active site [active]
1094466002783	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1094466002784	nucleotide binding region [chemical binding]; other site
1094466002785	ATP-binding site [chemical binding]; other site
1094466002786	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_IV; cd01994
1094466002787	Ligand Binding Site [chemical binding]; other site
1094466002788	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
1094466002789	Zn binding site [ion binding]; other site
1094466002790	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466002791	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
1094466002792	Part of AAA domain; Region: AAA_19; pfam13245
1094466002793	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
1094466002794	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
1094466002795	Histidine kinase; Region: His_kinase; pfam06580
1094466002796	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1094466002797	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466002798	active site
1094466002799	phosphorylation site [posttranslational modification]
1094466002800	intermolecular recognition site; other site
1094466002801	dimerization interface [polypeptide binding]; other site
1094466002802	LytTr DNA-binding domain; Region: LytTR; smart00850
1094466002803	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1094466002804	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1094466002805	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1094466002806	dimerization interface [polypeptide binding]; other site
1094466002807	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1094466002808	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1094466002809	RF-1 domain; Region: RF-1; pfam00472
1094466002810	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
1094466002811	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1094466002812	active site
1094466002813	Two component regulator propeller; Region: Reg_prop; pfam07494
1094466002814	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1094466002815	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1094466002816	metal binding site [ion binding]; metal-binding site
1094466002817	dimer interface [polypeptide binding]; other site
1094466002818	Protein of unknown function (DUF3810); Region: DUF3810; pfam12725
1094466002819	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1094466002820	active site clefts [active]
1094466002821	zinc binding site [ion binding]; other site
1094466002822	dimer interface [polypeptide binding]; other site
1094466002823	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
1094466002824	active site clefts [active]
1094466002825	zinc binding site [ion binding]; other site
1094466002826	dimer interface [polypeptide binding]; other site
1094466002827	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1094466002828	Sulfate transporter family; Region: Sulfate_transp; cl19250
1094466002829	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1094466002830	active site
1094466002831	dimer interface [polypeptide binding]; other site
1094466002832	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1094466002833	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1094466002834	intersubunit interface [polypeptide binding]; other site
1094466002835	Protein of unknown function (DUF4197); Region: DUF4197; pfam13852
1094466002836	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1094466002837	catalytic residues [active]
1094466002838	dimer interface [polypeptide binding]; other site
1094466002839	Predicted metalloprotease [General function prediction only]; Region: COG2321
1094466002840	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466002841	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1094466002842	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1094466002843	Outer membrane protein beta-barrel family; Region: OMP_b-brl_3; pfam14905
1094466002844	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1094466002845	catalytic residues [active]
1094466002846	CAAX protease self-immunity; Region: Abi; pfam02517
1094466002847	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1094466002848	AMP binding site [chemical binding]; other site
1094466002849	active site
1094466002850	acyl-activating enzyme (AAE) consensus motif; other site
1094466002851	CoA binding site [chemical binding]; other site
1094466002852	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1094466002853	Zn binding site [ion binding]; other site
1094466002854	Cadherin tandem repeat domain; Region: Cadherin_repeat; cd11304
1094466002855	Ca2+ binding site [ion binding]; other site
1094466002856	SprB repeat; Region: SprB; pfam13573
1094466002857	SprB repeat; Region: SprB; pfam13573
1094466002858	SprB repeat; Region: SprB; pfam13573
1094466002859	SprB repeat; Region: SprB; pfam13573
1094466002860	SprB repeat; Region: SprB; pfam13573
1094466002861	SprB repeat; Region: SprB; pfam13573
1094466002862	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466002863	Microcystin-dependent protein [Function unknown]; Region: MdpB; COG4675
1094466002864	Phage Tail Collar Domain; Region: Collar; pfam07484
1094466002865	3-methylcrotonyl-CoA carboxylase, beta chain; Region: PLN02820
1094466002866	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; cl19172
1094466002867	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; cl19172
1094466002868	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14970
1094466002869	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466002870	Walker A motif; other site
1094466002871	ATP binding site [chemical binding]; other site
1094466002872	Walker B motif; other site
1094466002873	arginine finger; other site
1094466002874	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1094466002875	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
1094466002876	TIGR00153 family protein; Region: TIGR00153
1094466002877	Phosphate transporter family; Region: PHO4; pfam01384
1094466002878	Phosphate-selective porin O and P; Region: Porin_O_P; cl19535
1094466002879	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1094466002880	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1094466002881	RF-1 domain; Region: RF-1; pfam00472
1094466002882	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1094466002883	Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212
1094466002884	tetramer interface [polypeptide binding]; other site
1094466002885	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466002886	catalytic residue [active]
1094466002887	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1094466002888	active site
1094466002889	Thioesterase-like superfamily; Region: 4HBT_2; pfam13279
1094466002890	active site 2 [active]
1094466002891	active site 1 [active]
1094466002892	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1094466002893	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1094466002894	active site
1094466002895	catalytic site [active]
1094466002896	substrate binding site [chemical binding]; other site
1094466002897	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1094466002898	GIY-YIG motif/motif A; other site
1094466002899	active site
1094466002900	catalytic site [active]
1094466002901	putative DNA binding site [nucleotide binding]; other site
1094466002902	metal binding site [ion binding]; metal-binding site
1094466002903	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
1094466002904	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1094466002905	catalytic residue [active]
1094466002906	Protein of unknown function (DUF1015); Region: DUF1015; pfam06245
1094466002907	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK05808
1094466002908	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1094466002909	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1094466002910	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1094466002911	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1094466002912	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1094466002913	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466002914	S-adenosylmethionine binding site [chemical binding]; other site
1094466002915	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
1094466002916	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1094466002917	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1094466002918	active site
1094466002919	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1094466002920	substrate binding site [chemical binding]; other site
1094466002921	catalytic residues [active]
1094466002922	dimer interface [polypeptide binding]; other site
1094466002923	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1094466002924	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1094466002925	CoA-ligase; Region: Ligase_CoA; pfam00549
1094466002926	Protein of unknown function (DUF2400); Region: DUF2400; pfam09674
1094466002927	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1094466002928	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1094466002929	Walker A/P-loop; other site
1094466002930	ATP binding site [chemical binding]; other site
1094466002931	Q-loop/lid; other site
1094466002932	ABC transporter signature motif; other site
1094466002933	Walker B; other site
1094466002934	D-loop; other site
1094466002935	H-loop/switch region; other site
1094466002936	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1094466002937	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1094466002938	active site
1094466002939	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
1094466002940	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1094466002941	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1094466002942	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1094466002943	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1094466002944	M28 Zn-Peptidases containing a PA domain insert and associated with a PDZ domain; Region: M28_like_PA_PDZ_associated; cd05663
1094466002945	Predicted aminopeptidases [General function prediction only]; Region: Iap; COG2234
1094466002946	metal binding site [ion binding]; metal-binding site
1094466002947	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1094466002948	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1094466002949	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
1094466002950	active site
1094466002951	dinuclear metal binding site [ion binding]; other site
1094466002952	dimerization interface [polypeptide binding]; other site
1094466002953	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1094466002954	dimer interface [polypeptide binding]; other site
1094466002955	active site
1094466002956	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1094466002957	folate binding site [chemical binding]; other site
1094466002958	fumarylacetoacetase; Region: PLN02856
1094466002959	Fumarylacetoacetase N-terminal; Region: FAA_hydrolase_N; pfam09298
1094466002960	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1094466002961	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1094466002962	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1094466002963	active site
1094466002964	metal binding site [ion binding]; metal-binding site
1094466002965	Fibronectin type 3 domain-containing protein [General function prediction only]; Region: COG3401
1094466002966	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466002967	bacillithiol system protein YtxJ; Region: B_thiol_YtxJ; TIGR04019
1094466002968	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1094466002969	Clp amino terminal domain; Region: Clp_N; pfam02861
1094466002970	Clp amino terminal domain; Region: Clp_N; pfam02861
1094466002971	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466002972	Walker A motif; other site
1094466002973	ATP binding site [chemical binding]; other site
1094466002974	Walker B motif; other site
1094466002975	arginine finger; other site
1094466002976	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1094466002977	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466002978	Walker A motif; other site
1094466002979	ATP binding site [chemical binding]; other site
1094466002980	Walker B motif; other site
1094466002981	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1094466002982	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
1094466002983	hypothetical protein; Provisional; Region: PRK10621
1094466002984	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1094466002985	Active site serine [active]
1094466002986	Predicted membrane protein (DUF2238); Region: DUF2238; pfam09997
1094466002987	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1094466002988	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1094466002989	Coenzyme A binding pocket [chemical binding]; other site
1094466002990	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1094466002991	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466002992	Walker A/P-loop; other site
1094466002993	ATP binding site [chemical binding]; other site
1094466002994	Q-loop/lid; other site
1094466002995	ABC transporter signature motif; other site
1094466002996	Walker B; other site
1094466002997	D-loop; other site
1094466002998	H-loop/switch region; other site
1094466002999	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
1094466003000	active site
1094466003001	catalytic residues [active]
1094466003002	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1094466003003	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1094466003004	ligand binding site [chemical binding]; other site
1094466003005	flexible hinge region; other site
1094466003006	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1094466003007	putative switch regulator; other site
1094466003008	non-specific DNA interactions [nucleotide binding]; other site
1094466003009	DNA binding site [nucleotide binding]
1094466003010	sequence specific DNA binding site [nucleotide binding]; other site
1094466003011	putative cAMP binding site [chemical binding]; other site
1094466003012	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
1094466003013	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1094466003014	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1094466003015	metal-binding site [ion binding]
1094466003016	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1094466003017	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1094466003018	Cytochrome oxidase maturation protein cbb3-type; Region: CcoS; pfam03597
1094466003019	putative bifunctional cbb3-type cytochrome c oxidase subunit I/II; Provisional; Region: PRK14485
1094466003020	Cytochrome cbb3 oxidase subunit I.  Cytochrome cbb3 oxidase, the terminal oxidase in the respiratory chains of proteobacteria, is a multi-chain transmembrane protein located in the cell membrane. Like other cytochrome oxidases, it catalyzes the reduction...; Region: cbb3_Oxidase_I; cd01661
1094466003021	Low-spin heme binding site [chemical binding]; other site
1094466003022	Putative water exit pathway; other site
1094466003023	Binuclear center (active site) [active]
1094466003024	Putative proton exit pathway; other site
1094466003025	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; pfam02433
1094466003026	Cbb3-type cytochrome oxidase component FixQ; Region: FixQ; pfam05545
1094466003027	N-terminal domain of cytochrome oxidase-cbb3, FixP; Region: FixP_N; pfam14715
1094466003028	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1094466003029	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
1094466003030	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1094466003031	4Fe-4S dicluster domain; Region: Fer4_18; pfam13746
1094466003032	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
1094466003033	IG-like fold at C-terminal of FixG, putative oxidoreductase; Region: FixG_C; pfam11614
1094466003034	FixH; Region: FixH; cl19376
1094466003035	Cytochrome C biogenesis protein transmembrane region; Region: DsbD_2; pfam13386
1094466003036	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466003037	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
1094466003038	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
1094466003039	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466003040	TPR motif; other site
1094466003041	TPR repeat; Region: TPR_11; pfam13414
1094466003042	binding surface
1094466003043	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
1094466003044	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1094466003045	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1094466003046	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1094466003047	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466003048	ligand binding site [chemical binding]; other site
1094466003049	Tandem repeat subunit of reelin and related proteins; Region: Reelin_subrepeat_like; cl15240
1094466003050	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1094466003051	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449
1094466003052	homodimer interface [polypeptide binding]; other site
1094466003053	substrate-cofactor binding pocket; other site
1094466003054	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466003055	catalytic residue [active]
1094466003056	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
1094466003057	acetolactate synthase, large subunit, biosynthetic type; Region: acolac_lg; TIGR00118
1094466003058	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1094466003059	PYR/PP interface [polypeptide binding]; other site
1094466003060	dimer interface [polypeptide binding]; other site
1094466003061	TPP binding site [chemical binding]; other site
1094466003062	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1094466003063	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1094466003064	TPP-binding site [chemical binding]; other site
1094466003065	dimer interface [polypeptide binding]; other site
1094466003066	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1094466003067	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1094466003068	putative valine binding site [chemical binding]; other site
1094466003069	dimer interface [polypeptide binding]; other site
1094466003070	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1094466003071	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1094466003072	ketol-acid reductoisomerase; Region: ilvC; TIGR00465
1094466003073	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1094466003074	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1094466003075	threonine dehydratase; Validated; Region: PRK08639
1094466003076	tetramer interface [polypeptide binding]; other site
1094466003077	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466003078	catalytic residue [active]
1094466003079	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1094466003080	putative Ile/Val binding site [chemical binding]; other site
1094466003081	NADH-ubiquinone/plastoquinone oxidoreductase chain 6; Region: Oxidored_q3; cl17265
1094466003082	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1094466003083	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1094466003084	FeS/SAM binding site; other site
1094466003085	HemN C-terminal domain; Region: HemN_C; pfam06969
1094466003086	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1094466003087	Interdomain contacts; other site
1094466003088	Cytokine receptor motif; other site
1094466003089	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466003090	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
1094466003091	Protein of unknown function (DUF342); Region: DUF342; cl19219
1094466003092	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
1094466003093	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1094466003094	non-specific DNA binding site [nucleotide binding]; other site
1094466003095	salt bridge; other site
1094466003096	sequence-specific DNA binding site [nucleotide binding]; other site
1094466003097	type II restriction m6 adenine DNA methyltransferase, Alw26I/Eco31I/Esp3I family; Region: met_A_Alw26; TIGR02987
1094466003098	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466003099	S-adenosylmethionine binding site [chemical binding]; other site
1094466003100	BsuBI/PstI restriction endonuclease C-terminus; Region: BsuBI_PstI_RE; pfam06616
1094466003101	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1094466003102	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl19078
1094466003103	active site
1094466003104	phosphorylation site [posttranslational modification]
1094466003105	intermolecular recognition site; other site
1094466003106	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl19078
1094466003107	phosphorylation site [posttranslational modification]
1094466003108	Two component regulator propeller; Region: Reg_prop; pfam07494
1094466003109	Streptogramin lyase [Defense mechanisms]; Region: Vgb; COG4257
1094466003110	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1094466003111	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1094466003112	Protein of unknown function (DUF2974); Region: DUF2974; pfam11187
1094466003113	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
1094466003114	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1094466003115	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cl17181
1094466003116	Erythromycin esterase; Region: Erythro_esteras; cl17110
1094466003117	Domain of unknown function (DUF4253); Region: DUF4253; pfam14062
1094466003118	DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024
1094466003119	catalytic residues [active]
1094466003120	Predicted transcriptional regulators [Transcription]; Region: COG1733
1094466003121	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1094466003122	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1094466003123	NADP binding site [chemical binding]; other site
1094466003124	Double zinc ribbon; Region: DZR; pfam12773
1094466003125	Protein of unknown function (DUF3667); Region: DUF3667; pfam12412
1094466003126	short chain dehydrogenase; Validated; Region: PRK06182
1094466003127	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1094466003128	NADP binding site [chemical binding]; other site
1094466003129	active site
1094466003130	steroid binding site; other site
1094466003131	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1094466003132	active site
1094466003133	intersubunit interactions; other site
1094466003134	catalytic residue [active]
1094466003135	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1094466003136	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1094466003137	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1094466003138	ABC transporter; Region: ABC_tran_2; pfam12848
1094466003139	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1094466003140	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1094466003141	Methyltransferase domain; Region: Methyltransf_18; pfam12847
1094466003142	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466003143	S-adenosylmethionine binding site [chemical binding]; other site
1094466003144	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1094466003145	active site
1094466003146	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
1094466003147	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1094466003148	cytochrome c-550; Provisional; Region: psbV; cl17239
1094466003149	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1094466003150	hydrophobic ligand binding site; other site
1094466003151	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
1094466003152	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Deinococcus radiodurans DR2231 protein and its bacterial homologs; Region: NTP-PPase_DR2231_like; cd11530
1094466003153	metal binding site [ion binding]; metal-binding site
1094466003154	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
1094466003155	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1094466003156	homodimer interface [polypeptide binding]; other site
1094466003157	substrate-cofactor binding pocket; other site
1094466003158	catalytic residue [active]
1094466003159	Bacterial SH3 domain; Region: SH3_3; pfam08239
1094466003160	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1094466003161	NlpC/P60 family; Region: NLPC_P60; pfam00877
1094466003162	acetyl-CoA C-acetyltransferase; Region: PLN02644
1094466003163	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1094466003164	dimer interface [polypeptide binding]; other site
1094466003165	active site
1094466003166	YceI-like domain; Region: YceI; pfam04264
1094466003167	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1094466003168	dimer interface [polypeptide binding]; other site
1094466003169	FMN binding site [chemical binding]; other site
1094466003170	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
1094466003171	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1094466003172	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1094466003173	active site residue [active]
1094466003174	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1094466003175	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
1094466003176	S1 domain; Region: S1_2; pfam13509
1094466003177	HPP family; Region: HPP; pfam04982
1094466003178	Beta-lactamase; Region: Beta-lactamase; pfam00144
1094466003179	Bacterial PH domain; Region: bPH_4; pfam06713
1094466003180	Dihydroxynaphthoic acid synthase [Coenzyme metabolism]; Region: MenB; COG0447
1094466003181	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1094466003182	substrate binding site [chemical binding]; other site
1094466003183	oxyanion hole (OAH) forming residues; other site
1094466003184	trimer interface [polypeptide binding]; other site
1094466003185	Bacterial PH domain; Region: bPH_2; pfam03703
1094466003186	Predicted membrane protein [Function unknown]; Region: COG3428
1094466003187	Bacterial PH domain; Region: bPH_2; pfam03703
1094466003188	Bacterial PH domain; Region: bPH_2; pfam03703
1094466003189	Bacterial PH domain; Region: bPH_2; pfam03703
1094466003190	Lipase maturation factor; Region: LMF1; pfam06762
1094466003191	1,4-Dihydroxy-2-naphthoate octaprenyltransferase; Region: PT_UbiA_UBIAD1; cd13962
1094466003192	putative active site [active]
1094466003193	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1094466003194	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466003195	binding surface
1094466003196	TPR motif; other site
1094466003197	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1094466003198	o-succinylbenzoate synthase; Region: menC_gamma/gm+; TIGR01927
1094466003199	active site
1094466003200	Domain of unknown function (DUF4440); Region: DUF4440; pfam14534
1094466003201	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1094466003202	active site
1094466003203	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1094466003204	nudix motif; other site
1094466003205	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1094466003206	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
1094466003207	HlyD family secretion protein; Region: HlyD_3; pfam13437
1094466003208	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1094466003209	MMPL family; Region: MMPL; cl14618
1094466003210	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1094466003211	Outer membrane efflux protein; Region: OEP; pfam02321
1094466003212	Outer membrane efflux protein; Region: OEP; pfam02321
1094466003213	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1094466003214	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
1094466003215	active site
1094466003216	nucleophile elbow; other site
1094466003217	Peptidase M14-like domain; uncharacterized subgroup; Region: M14-like_1_4; cd06241
1094466003218	putative active site [active]
1094466003219	Zn binding site [ion binding]; other site
1094466003220	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1094466003221	active site
1094466003222	(T/H)XGH motif; other site
1094466003223	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1094466003224	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1094466003225	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1094466003226	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1094466003227	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1094466003228	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1094466003229	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1094466003230	RNA binding surface [nucleotide binding]; other site
1094466003231	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1094466003232	active site
1094466003233	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466003234	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
1094466003235	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
1094466003236	B12 binding site [chemical binding]; other site
1094466003237	cobalt ligand [ion binding]; other site
1094466003238	Putative periplasmic protein kinase ArgK and related GTPases of G3E family [Amino acid transport and metabolism]; Region: ArgK; COG1703
1094466003239	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1094466003240	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, unknown subfamily 1; composed of uncharacterized bacterial proteins containing a C-terminal MCM domain. MCM catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA. The...; Region: MM_CoA_mutase_1; cd03678
1094466003241	putative active site [active]
1094466003242	putative substrate binding site [chemical binding]; other site
1094466003243	putative coenzyme B12 binding site [chemical binding]; other site
1094466003244	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1094466003245	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
1094466003246	Putative periplasmic protein kinase ArgK and related GTPases of G3E family [Amino acid transport and metabolism]; Region: ArgK; COG1703
1094466003247	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
1094466003248	Walker A; other site
1094466003249	Membrane transport protein; Region: Mem_trans; cl09117
1094466003250	FAD binding domain; Region: FAD_binding_4; pfam01565
1094466003251	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
1094466003252	FAD linked oxidases, C-terminal domain; Region: FAD-oxidase_C; pfam02913
1094466003253	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12901
1094466003254	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1094466003255	SecA preprotein cross-linking domain; Region: SecA_PP_bind; pfam01043
1094466003256	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1094466003257	SecA Wing and Scaffold domain; Region: SecA_SW; pfam07516
1094466003258	Protein of unknown function (DUF2795); Region: DUF2795; pfam11387
1094466003259	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
1094466003260	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1094466003261	Domain of Unknown Function (DUF1543); Region: DUF1543; pfam07566
1094466003262	Domain of Unknown Function (DUF1543); Region: DUF1543; pfam07566
1094466003263	Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968
1094466003264	Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437
1094466003265	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1094466003266	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1094466003267	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466003268	ligand binding site [chemical binding]; other site
1094466003269	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1094466003270	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466003271	ligand binding site [chemical binding]; other site
1094466003272	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
1094466003273	ligand binding site [chemical binding]; other site
1094466003274	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1094466003275	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466003276	ligand binding site [chemical binding]; other site
1094466003277	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
1094466003278	ligand binding site [chemical binding]; other site
1094466003279	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466003280	ligand binding site [chemical binding]; other site
1094466003281	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
1094466003282	ligand binding site [chemical binding]; other site
1094466003283	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466003284	ligand binding site [chemical binding]; other site
1094466003285	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
1094466003286	dimerization interface [polypeptide binding]; other site
1094466003287	ATP binding site [chemical binding]; other site
1094466003288	GMP synthase; Reviewed; Region: guaA; PRK00074
1094466003289	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1094466003290	AMP/PPi binding site [chemical binding]; other site
1094466003291	candidate oxyanion hole; other site
1094466003292	catalytic triad [active]
1094466003293	potential glutamine specificity residues [chemical binding]; other site
1094466003294	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1094466003295	ATP Binding subdomain [chemical binding]; other site
1094466003296	Ligand Binding sites [chemical binding]; other site
1094466003297	Dimerization subdomain; other site
1094466003298	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1094466003299	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1094466003300	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1094466003301	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1094466003302	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1094466003303	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1094466003304	Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type I periplasmic binding fold protein superfamily; Region: PBP1_ABC_transporter_LIVBP_like; cd06268
1094466003305	ligand binding site [chemical binding]; other site
1094466003306	OsmC-like protein; Region: OsmC; pfam02566
1094466003307	Protein of unknown function (DUF3820); Region: DUF3820; pfam12843
1094466003308	CTP synthetase; Validated; Region: pyrG; PRK05380
1094466003309	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1094466003310	Catalytic site [active]
1094466003311	active site
1094466003312	UTP binding site [chemical binding]; other site
1094466003313	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1094466003314	active site
1094466003315	putative oxyanion hole; other site
1094466003316	catalytic triad [active]
1094466003317	membrane protein insertase; Provisional; Region: PRK01318
1094466003318	YidC periplasmic domain; Region: YidC_periplas; pfam14849
1094466003319	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1094466003320	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
1094466003321	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
1094466003322	Pyrroline-5-carboxylate reductase dimerization; Region: P5CR_dimer; pfam14748
1094466003323	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
1094466003324	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
1094466003325	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1094466003326	Ligand Binding Site [chemical binding]; other site
1094466003327	Peptidase S8 family domain, uncharacterized subfamily 9; Region: Peptidases_S8_9; cd07493
1094466003328	Subtilase family; Region: Peptidase_S8; pfam00082
1094466003329	active site
1094466003330	catalytic triad [active]
1094466003331	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466003332	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
1094466003333	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1094466003334	FMN binding site [chemical binding]; other site
1094466003335	substrate binding site [chemical binding]; other site
1094466003336	putative catalytic residue [active]
1094466003337	aminodeoxychorismate synthase, component I, clade 2; Region: PabB-clade2; TIGR01824
1094466003338	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1094466003339	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1094466003340	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1094466003341	Ligand Binding Site [chemical binding]; other site
1094466003342	TilS substrate C-terminal domain; Region: TilS_C; smart00977
1094466003343	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1094466003344	Thioredoxin-like; Region: Thioredoxin_7; pfam13899
1094466003345	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
1094466003346	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1094466003347	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl18944
1094466003348	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466003349	Walker A motif; other site
1094466003350	ATP binding site [chemical binding]; other site
1094466003351	Walker B motif; other site
1094466003352	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1094466003353	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
1094466003354	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466003355	TPR motif; other site
1094466003356	binding surface
1094466003357	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1094466003358	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1094466003359	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466003360	ligand binding site [chemical binding]; other site
1094466003361	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
1094466003362	potential frameshift: common BLAST hit: gi|146302265|ref|YP_001196856.1| von Willebrand factor, type A
1094466003363	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
1094466003364	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1094466003365	SprB repeat; Region: SprB; pfam13573
1094466003366	Bacterial Ig-like domain (group 3); Region: Big_3_3; pfam13750
1094466003367	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1094466003368	catalytic core [active]
1094466003369	polyphosphate kinase; Provisional; Region: PRK05443
1094466003370	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1094466003371	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1094466003372	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
1094466003373	domain interface [polypeptide binding]; other site
1094466003374	active site
1094466003375	catalytic site [active]
1094466003376	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
1094466003377	domain interface [polypeptide binding]; other site
1094466003378	active site
1094466003379	catalytic site [active]
1094466003380	Ppx/GppA phosphatase family; Region: Ppx-GppA; cl19483
1094466003381	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1094466003382	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1094466003383	Zinc-dependent metalloprotease, pappalysin_like subfamily. The pregnancy-associated plasma protein A (PAPP-A or pappalysin-1) cleaves insulin-like growth factor-binding proteins 4 and 5, thereby promoting cell growth by releasing bound growth factor; Region: ZnMc_pappalysin_like; cd04275
1094466003384	active site
1094466003385	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1094466003386	Domain of unknown function (DUF4159); Region: DUF4159; pfam13709
1094466003387	UGMP family protein; Validated; Region: PRK09604
1094466003388	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1094466003389	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
1094466003390	Family of unknown function (DUF490); Region: DUF490; pfam04357
1094466003391	6-phosphofructokinase; Provisional; Region: PRK03202
1094466003392	active site
1094466003393	ADP/pyrophosphate binding site [chemical binding]; other site
1094466003394	dimerization interface [polypeptide binding]; other site
1094466003395	allosteric effector site; other site
1094466003396	fructose-1,6-bisphosphate binding site; other site
1094466003397	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
1094466003398	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1094466003399	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1094466003400	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1094466003401	Domain of unknown function (DUF389); Region: DUF389; pfam04087
1094466003402	Na+/H+ antiporter 1; Region: Na_H_antiport_1; cl01133
1094466003403	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1094466003404	active site
1094466003405	dimer interfaces [polypeptide binding]; other site
1094466003406	catalytic residues [active]
1094466003407	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
1094466003408	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466003409	S-adenosylmethionine binding site [chemical binding]; other site
1094466003410	Protein of unknown function (DUF3822); Region: DUF3822; pfam12864
1094466003411	AAA domain; Region: AAA_30; pfam13604
1094466003412	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
1094466003413	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1094466003414	Ligand binding site; other site
1094466003415	oligomer interface; other site
1094466003416	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1094466003417	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1094466003418	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1094466003419	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1094466003420	Ion channel; Region: Ion_trans_2; pfam07885
1094466003421	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466003422	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
1094466003423	putative acyl-acceptor binding pocket; other site
1094466003424	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1094466003425	non-specific DNA binding site [nucleotide binding]; other site
1094466003426	salt bridge; other site
1094466003427	sequence-specific DNA binding site [nucleotide binding]; other site
1094466003428	Peptidase M14-like domain; uncharacterized subgroup; Region: M14-like_1_2; cd06239
1094466003429	putative active site [active]
1094466003430	Zn binding site [ion binding]; other site
1094466003431	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1094466003432	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1094466003433	putative DNA binding site [nucleotide binding]; other site
1094466003434	putative Zn2+ binding site [ion binding]; other site
1094466003435	AsnC family; Region: AsnC_trans_reg; pfam01037
1094466003436	DinB superfamily; Region: DinB_2; pfam12867
1094466003437	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
1094466003438	Deoxyhypusine synthase; Region: DS; cl00826
1094466003439	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
1094466003440	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1094466003441	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1094466003442	catalytic residue [active]
1094466003443	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1094466003444	active site
1094466003445	dimer interface [polypeptide binding]; other site
1094466003446	metal binding site [ion binding]; metal-binding site
1094466003447	proline dehydrogenase; Region: PLN02681
1094466003448	Proline dehydrogenase; Region: Pro_dh; pfam01619
1094466003449	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
1094466003450	catalytic triad [active]
1094466003451	Protein of unknown function, DUF393; Region: DUF393; cl01136
1094466003452	MutS domain III; Region: MutS_III; pfam05192
1094466003453	DNA-binding domain of DNA mismatch repair MUTS family; Region: MUTSd; smart00533
1094466003454	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466003455	Walker A/P-loop; other site
1094466003456	ATP binding site [chemical binding]; other site
1094466003457	Q-loop/lid; other site
1094466003458	ABC transporter signature motif; other site
1094466003459	Walker B; other site
1094466003460	D-loop; other site
1094466003461	H-loop/switch region; other site
1094466003462	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
1094466003463	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1094466003464	ligand binding site [chemical binding]; other site
1094466003465	active site
1094466003466	UGI interface [polypeptide binding]; other site
1094466003467	catalytic site [active]
1094466003468	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl19158
1094466003469	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1094466003470	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1094466003471	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; cl19131
1094466003472	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1094466003473	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1094466003474	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1094466003475	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1094466003476	putative rRNA binding site [nucleotide binding]; other site
1094466003477	Isopenicillin N synthase and related dioxygenases [General function prediction only]; Region: PcbC; COG3491
1094466003478	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
1094466003479	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
1094466003480	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1094466003481	tetramer interface [polypeptide binding]; other site
1094466003482	TPP-binding site [chemical binding]; other site
1094466003483	heterodimer interface [polypeptide binding]; other site
1094466003484	phosphorylation loop region [posttranslational modification]
1094466003485	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1094466003486	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1094466003487	alpha subunit interface [polypeptide binding]; other site
1094466003488	TPP binding site [chemical binding]; other site
1094466003489	heterodimer interface [polypeptide binding]; other site
1094466003490	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1094466003491	Peptidase family M54, also called archaemetzincins or archaelysins; Region: Peptidase_M54; cd11375
1094466003492	active site
1094466003493	Zn binding site [ion binding]; other site
1094466003494	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1094466003495	Homeodomain-like domain; Region: HTH_23; pfam13384
1094466003496	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1094466003497	metabolite-proton symporter; Region: 2A0106; TIGR00883
1094466003498	putative substrate translocation pore; other site
1094466003499	Na+/proline symporter [Amino acid transport and metabolism / General function prediction only]; Region: PutP; COG0591
1094466003500	Na binding site [ion binding]; other site
1094466003501	Type III pantothenate kinase; Region: Pan_kinase; cl17198
1094466003502	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1094466003503	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
1094466003504	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1094466003505	dimer interface [polypeptide binding]; other site
1094466003506	phosphorylation site [posttranslational modification]
1094466003507	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466003508	ATP binding site [chemical binding]; other site
1094466003509	Mg2+ binding site [ion binding]; other site
1094466003510	G-X-G motif; other site
1094466003511	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1094466003512	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466003513	active site
1094466003514	phosphorylation site [posttranslational modification]
1094466003515	intermolecular recognition site; other site
1094466003516	dimerization interface [polypeptide binding]; other site
1094466003517	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
1094466003518	Propionyl-CoA synthetase (PrpE); Region: PrpE; cd05967
1094466003519	acyl-activating enzyme (AAE) consensus motif; other site
1094466003520	putative AMP binding site [chemical binding]; other site
1094466003521	putative active site [active]
1094466003522	putative CoA binding site [chemical binding]; other site
1094466003523	acetyl-CoA synthetase; Provisional; Region: PRK00174
1094466003524	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1094466003525	active site
1094466003526	CoA binding site [chemical binding]; other site
1094466003527	acyl-activating enzyme (AAE) consensus motif; other site
1094466003528	AMP binding site [chemical binding]; other site
1094466003529	acetate binding site [chemical binding]; other site
1094466003530	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1094466003531	active site
1094466003532	catalytic site [active]
1094466003533	substrate binding site [chemical binding]; other site
1094466003534	Predicted signal-transduction protein containing cAMP-binding and CBS domains [Signal transduction mechanisms]; Region: COG2905
1094466003535	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1094466003536	ligand binding site [chemical binding]; other site
1094466003537	flexible hinge region; other site
1094466003538	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1094466003539	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1094466003540	metal binding triad; other site
1094466003541	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; cl19627
1094466003542	integral membrane protein; Region: integ_memb_HG; TIGR03954
1094466003543	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1094466003544	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1094466003545	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
1094466003546	nudix motif; other site
1094466003547	Conserved hypothetical protein (DUF2461); Region: DUF2461; pfam09365
1094466003548	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1094466003549	o-succinylbenzoate synthase; Region: menC_lowGC/arch; TIGR01928
1094466003550	active site
1094466003551	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1094466003552	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1094466003553	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1094466003554	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1094466003555	metal binding site [ion binding]; metal-binding site
1094466003556	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1094466003557	substrate binding site [chemical binding]; other site
1094466003558	glutamase interaction surface [polypeptide binding]; other site
1094466003559	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1094466003560	catalytic residues [active]
1094466003561	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1094466003562	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13142
1094466003563	putative active site [active]
1094466003564	oxyanion strand; other site
1094466003565	catalytic triad [active]
1094466003566	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1094466003567	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1094466003568	active site
1094466003569	motif I; other site
1094466003570	motif II; other site
1094466003571	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1094466003572	putative active site pocket [active]
1094466003573	4-fold oligomerization interface [polypeptide binding]; other site
1094466003574	metal binding residues [ion binding]; metal-binding site
1094466003575	3-fold/trimer interface [polypeptide binding]; other site
1094466003576	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
1094466003577	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1094466003578	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466003579	homodimer interface [polypeptide binding]; other site
1094466003580	catalytic residue [active]
1094466003581	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1094466003582	histidinol dehydrogenase; Region: hisD; TIGR00069
1094466003583	NAD binding site [chemical binding]; other site
1094466003584	dimerization interface [polypeptide binding]; other site
1094466003585	product binding site; other site
1094466003586	substrate binding site [chemical binding]; other site
1094466003587	zinc binding site [ion binding]; other site
1094466003588	catalytic residues [active]
1094466003589	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1094466003590	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1094466003591	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1094466003592	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; cl01503
1094466003593	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1094466003594	Sulfatase; Region: Sulfatase; pfam00884
1094466003595	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1094466003596	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
1094466003597	NAD(P) binding site [chemical binding]; other site
1094466003598	homotetramer interface [polypeptide binding]; other site
1094466003599	homodimer interface [polypeptide binding]; other site
1094466003600	active site
1094466003601	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
1094466003602	di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039
1094466003603	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1094466003604	CoA binding domain; Region: CoA_binding; smart00881
1094466003605	CoA-ligase; Region: Ligase_CoA; pfam00549
1094466003606	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1094466003607	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1094466003608	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1094466003609	trimer interface [polypeptide binding]; other site
1094466003610	active site
1094466003611	UDP-GlcNAc binding site [chemical binding]; other site
1094466003612	lipid binding site [chemical binding]; lipid-binding site
1094466003613	elongation factor P; Validated; Region: PRK00529
1094466003614	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1094466003615	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1094466003616	RNA binding site [nucleotide binding]; other site
1094466003617	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1094466003618	RNA binding site [nucleotide binding]; other site
1094466003619	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1094466003620	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1094466003621	active site
1094466003622	bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed; Region: PRK13188
1094466003623	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1094466003624	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1094466003625	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1094466003626	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1094466003627	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1094466003628	trimer interface [polypeptide binding]; other site
1094466003629	active site
1094466003630	UDP-GlcNAc binding site [chemical binding]; other site
1094466003631	lipid binding site [chemical binding]; lipid-binding site
1094466003632	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
1094466003633	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1094466003634	Zn2+ binding site [ion binding]; other site
1094466003635	Mg2+ binding site [ion binding]; other site
1094466003636	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466003637	active site
1094466003638	phosphorylation site [posttranslational modification]
1094466003639	intermolecular recognition site; other site
1094466003640	dimerization interface [polypeptide binding]; other site
1094466003641	PglZ domain; Region: PglZ; pfam08665
1094466003642	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
1094466003643	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
1094466003644	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
1094466003645	hexamer interface [polypeptide binding]; other site
1094466003646	ligand binding site [chemical binding]; other site
1094466003647	putative active site [active]
1094466003648	NAD(P) binding site [chemical binding]; other site
1094466003649	Domain of unknown function (DUF4258); Region: DUF4258; pfam14076
1094466003650	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1094466003651	Tetramer interface [polypeptide binding]; other site
1094466003652	active site
1094466003653	FMN-binding site [chemical binding]; other site
1094466003654	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1094466003655	PrcB C-terminal; Region: PrcB_C; pfam14343
1094466003656	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA; Region: thiol_BshA; TIGR03999
1094466003657	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_5; cd04962
1094466003658	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
1094466003659	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1094466003660	Beta-lactamase; Region: Beta-lactamase; cl17358
1094466003661	Glycine cleavage system regulatory protein [Amino acid transport and metabolism]; Region: GcvR; COG2716
1094466003662	CT domains found N-terminal of phosphoserine phosphatase (PSP, SerB); Region: ACT_PSP_1; cd04870
1094466003663	ACT domains found N-terminal of phosphoserine phosphatase (PSP, SerB); Region: ACT_PSP_2; cd04871
1094466003664	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
1094466003665	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
1094466003666	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1094466003667	motif II; other site
1094466003668	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1094466003669	Cysteine-rich domain; Region: CCG; pfam02754
1094466003670	Cysteine-rich domain; Region: CCG; pfam02754
1094466003671	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
1094466003672	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
1094466003673	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
1094466003674	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
1094466003675	virulence factor Mce family protein; Region: Mtu_fam_mce; TIGR00996
1094466003676	mce related protein; Region: MCE; pfam02470
1094466003677	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1094466003678	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1094466003679	active site
1094466003680	metal binding site [ion binding]; metal-binding site
1094466003681	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1094466003682	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1094466003683	active site
1094466003684	metal binding site [ion binding]; metal-binding site
1094466003685	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
1094466003686	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1094466003687	homotrimer interaction site [polypeptide binding]; other site
1094466003688	putative active site [active]
1094466003689	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
1094466003690	pyridoxamine-phosphate oxidase; Region: pdxH; TIGR00558
1094466003691	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1094466003692	Pyridoxine 5'-phosphate oxidase C-terminal dimerization region; Region: PNPOx_C; pfam10590
1094466003693	ribonuclease Z; Reviewed; Region: PRK00055
1094466003694	sucrose synthase; Region: PLN00142
1094466003695	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1094466003696	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1094466003697	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1094466003698	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1094466003699	active site
1094466003700	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1094466003701	active site
1094466003702	dimer interface [polypeptide binding]; other site
1094466003703	Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Region: PT_UbiA_DGGGPS; cd13961
1094466003704	putative active site [active]
1094466003705	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
1094466003706	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1094466003707	active site
1094466003708	motif I; other site
1094466003709	motif II; other site
1094466003710	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
1094466003711	hypothetical protein; Validated; Region: PRK02101
1094466003712	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1094466003713	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1094466003714	putative substrate translocation pore; other site
1094466003715	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1094466003716	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1094466003717	HlyD family secretion protein; Region: HlyD_3; pfam13437
1094466003718	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1094466003719	Outer membrane efflux protein; Region: OEP; pfam02321
1094466003720	Outer membrane efflux protein; Region: OEP; pfam02321
1094466003721	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1094466003722	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1094466003723	YsiA-like protein, C-terminal region; Region: TetR_C_4; pfam08359
1094466003724	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1094466003725	substrate binding site [chemical binding]; other site
1094466003726	active site
1094466003727	catalytic residues [active]
1094466003728	heterodimer interface [polypeptide binding]; other site
1094466003729	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1094466003730	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466003731	catalytic residue [active]
1094466003732	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1094466003733	active site
1094466003734	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1094466003735	active site
1094466003736	ribulose/triose binding site [chemical binding]; other site
1094466003737	phosphate binding site [ion binding]; other site
1094466003738	substrate (anthranilate) binding pocket [chemical binding]; other site
1094466003739	product (indole) binding pocket [chemical binding]; other site
1094466003740	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1094466003741	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1094466003742	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1094466003743	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1094466003744	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1094466003745	glutamine binding [chemical binding]; other site
1094466003746	catalytic triad [active]
1094466003747	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
1094466003748	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1094466003749	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1094466003750	Smr domain; Region: Smr; pfam01713
1094466003751	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1094466003752	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1094466003753	catalytic residue [active]
1094466003754	Protein of unknown function (DUF2911); Region: DUF2911; pfam11138
1094466003755	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466003756	TPR repeat; Region: TPR_11; pfam13414
1094466003757	binding surface
1094466003758	TPR motif; other site
1094466003759	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_3; cd07820
1094466003760	putative hydrophobic ligand binding site [chemical binding]; other site
1094466003761	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
1094466003762	DNA photolyase; Region: DNA_photolyase; pfam00875
1094466003763	FAD binding domain of DNA photolyase; Region: FAD_binding_7; pfam03441
1094466003764	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
1094466003765	DNA photolyase; Region: DNA_photolyase; pfam00875
1094466003766	FAD binding domain of DNA photolyase; Region: FAD_binding_7; pfam03441
1094466003767	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
1094466003768	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1094466003769	motif II; other site
1094466003770	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1094466003771	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1094466003772	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1094466003773	DNA binding residues [nucleotide binding]
1094466003774	Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only]; Region: COG4447
1094466003775	Photosynthesis system II assembly factor YCF48; Region: PSII_BNR; pfam14870
1094466003776	Spumavirus gag protein; Region: Gag_spuma; pfam03276
1094466003777	16S rRNA methyltransferase B; Provisional; Region: PRK14901
1094466003778	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1094466003779	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466003780	S-adenosylmethionine binding site [chemical binding]; other site
1094466003781	Endonuclease I; Region: Endonuclease_1; pfam04231
1094466003782	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466003783	Lipocalin-like domain; Region: Lipocalin_4; pfam13648
1094466003784	transcription termination factor Rho; Provisional; Region: PRK12678
1094466003785	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
1094466003786	late transcription factor VLTF-4; Provisional; Region: PHA03089
1094466003787	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1094466003788	RNA binding site [nucleotide binding]; other site
1094466003789	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1094466003790	multimer interface [polypeptide binding]; other site
1094466003791	Walker A motif; other site
1094466003792	ATP binding site [chemical binding]; other site
1094466003793	Walker B motif; other site
1094466003794	Domain of unknown function (DUF4293); Region: DUF4293; pfam14126
1094466003795	Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850
1094466003796	active site
1094466003797	metal binding site [ion binding]; metal-binding site
1094466003798	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1094466003799	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1094466003800	dimerization interface 3.5A [polypeptide binding]; other site
1094466003801	active site
1094466003802	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1094466003803	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1094466003804	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1094466003805	Walker A/P-loop; other site
1094466003806	ATP binding site [chemical binding]; other site
1094466003807	Q-loop/lid; other site
1094466003808	ABC transporter signature motif; other site
1094466003809	Walker B; other site
1094466003810	D-loop; other site
1094466003811	H-loop/switch region; other site
1094466003812	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
1094466003813	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1094466003814	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1094466003815	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1094466003816	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
1094466003817	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1094466003818	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1094466003819	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1094466003820	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1094466003821	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1094466003822	motif II; other site
1094466003823	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1094466003824	Permease; Region: Permease; pfam02405
1094466003825	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
1094466003826	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466003827	Walker A/P-loop; other site
1094466003828	ATP binding site [chemical binding]; other site
1094466003829	Q-loop/lid; other site
1094466003830	ABC transporter signature motif; other site
1094466003831	Walker B; other site
1094466003832	D-loop; other site
1094466003833	H-loop/switch region; other site
1094466003834	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1094466003835	mce related protein; Region: MCE; pfam02470
1094466003836	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1094466003837	dimer interface [polypeptide binding]; other site
1094466003838	phosphoglucosamine mutase; Region: Arch_GlmM; TIGR03990
1094466003839	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
1094466003840	active site
1094466003841	substrate binding site [chemical binding]; other site
1094466003842	metal binding site [ion binding]; metal-binding site
1094466003843	Protein of unknown function, DUF479; Region: DUF479; cl01203
1094466003844	A new structural DNA glycosylase; Region: AlkD_like; cl11434
1094466003845	active site
1094466003846	putative voltage-gated ClC-type chloride channel ClcB; Provisional; Region: PRK01862
1094466003847	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1094466003848	Cl- selectivity filter; other site
1094466003849	Cl- binding residues [ion binding]; other site
1094466003850	pore gating glutamate residue; other site
1094466003851	dimer interface [polypeptide binding]; other site
1094466003852	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1094466003853	Prolipoprotein diacylglyceryl transferase; Region: LGT; cl00478
1094466003854	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG1964
1094466003855	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1094466003856	FeS/SAM binding site; other site
1094466003857	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Region: EPSP_synthase; pfam00275
1094466003858	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1094466003859	hinge; other site
1094466003860	active site
1094466003861	Domain of unknown function (DUF4290); Region: DUF4290; pfam14123
1094466003862	Protein of unknown function (DUF493); Region: DUF493; pfam04359
1094466003863	AAA domain; Region: AAA_33; pfam13671
1094466003864	AAA domain; Region: AAA_28; pfam13521
1094466003865	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1094466003866	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1094466003867	ATP binding site [chemical binding]; other site
1094466003868	putative Mg++ binding site [ion binding]; other site
1094466003869	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1094466003870	nucleotide binding region [chemical binding]; other site
1094466003871	ATP-binding site [chemical binding]; other site
1094466003872	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1094466003873	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1094466003874	putative active site [active]
1094466003875	substrate binding site [chemical binding]; other site
1094466003876	putative cosubstrate binding site; other site
1094466003877	catalytic site [active]
1094466003878	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1094466003879	substrate binding site [chemical binding]; other site
1094466003880	histone-like DNA-binding protein HU; Region: HU; cd13831
1094466003881	dimer interface [polypeptide binding]; other site
1094466003882	DNA binding site [nucleotide binding]
1094466003883	Uncharacterized ACR, COG1678; Region: DUF179; pfam02622
1094466003884	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449
1094466003885	homodimer interface [polypeptide binding]; other site
1094466003886	substrate-cofactor binding pocket; other site
1094466003887	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466003888	catalytic residue [active]
1094466003889	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1094466003890	active site
1094466003891	catalytic residues [active]
1094466003892	DNA binding site [nucleotide binding]
1094466003893	Int/Topo IB signature motif; other site
1094466003894	HipA N-terminal domain; Region: Couple_hipA; cl11853
1094466003895	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1094466003896	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1094466003897	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1094466003898	non-specific DNA binding site [nucleotide binding]; other site
1094466003899	salt bridge; other site
1094466003900	sequence-specific DNA binding site [nucleotide binding]; other site
1094466003901	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1094466003902	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1094466003903	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1094466003904	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
1094466003905	MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032
1094466003906	putative active site [active]
1094466003907	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1094466003908	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1094466003909	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1094466003910	Yip1 domain; Region: Yip1; pfam04893
1094466003911	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
1094466003912	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1094466003913	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1094466003914	ATP binding site [chemical binding]; other site
1094466003915	putative Mg++ binding site [ion binding]; other site
1094466003916	EcoEI R protein C-terminal; Region: EcoEI_R_C; pfam08463
1094466003917	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1094466003918	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1094466003919	active site
1094466003920	DNA binding site [nucleotide binding]
1094466003921	Int/Topo IB signature motif; other site
1094466003922	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1094466003923	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1094466003924	active site
1094466003925	DNA binding site [nucleotide binding]
1094466003926	Int/Topo IB signature motif; other site
1094466003927	CHC2 zinc finger; Region: zf-CHC2; cl17510
1094466003928	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1094466003929	active site
1094466003930	metal binding site [ion binding]; metal-binding site
1094466003931	interdomain interaction site; other site
1094466003932	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466003933	Walker A motif; other site
1094466003934	ATP binding site [chemical binding]; other site
1094466003935	Walker B motif; other site
1094466003936	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1094466003937	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1094466003938	non-specific DNA binding site [nucleotide binding]; other site
1094466003939	salt bridge; other site
1094466003940	sequence-specific DNA binding site [nucleotide binding]; other site
1094466003941	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
1094466003942	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466003943	Relaxase/Mobilisation nuclease domain; Region: Relaxase; cl19391
1094466003944	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
1094466003945	putative transposase OrfB; Reviewed; Region: PHA02517
1094466003946	HTH-like domain; Region: HTH_21; pfam13276
1094466003947	Integrase core domain; Region: rve; pfam00665
1094466003948	Integrase core domain; Region: rve_3; pfam13683
1094466003949	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1094466003950	Transposase; Region: HTH_Tnp_1; cl17663
1094466003951	Uncharacterized alpha/beta hydrolase domain (DUF2235); Region: DUF2235; cl01480
1094466003952	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1094466003953	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
1094466003954	HlyD family secretion protein; Region: HlyD_3; pfam13437
1094466003955	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1094466003956	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
1094466003957	putative active site [active]
1094466003958	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1094466003959	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466003960	Walker A/P-loop; other site
1094466003961	ATP binding site [chemical binding]; other site
1094466003962	Q-loop/lid; other site
1094466003963	ABC transporter signature motif; other site
1094466003964	Walker B; other site
1094466003965	D-loop; other site
1094466003966	H-loop/switch region; other site
1094466003967	SPASM domain peptide maturase, grasp-with-spasm system; Region: SPASM_w_grasp; TIGR04193
1094466003968	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1094466003969	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1094466003970	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1094466003971	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466003972	active site
1094466003973	phosphorylation site [posttranslational modification]
1094466003974	intermolecular recognition site; other site
1094466003975	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
1094466003976	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466003977	TPR motif; other site
1094466003978	binding surface
1094466003979	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1094466003980	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1094466003981	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466003982	ligand binding site [chemical binding]; other site
1094466003983	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1094466003984	Transposase; Region: HTH_Tnp_1; cl17663
1094466003985	putative transposase OrfB; Reviewed; Region: PHA02517
1094466003986	HTH-like domain; Region: HTH_21; pfam13276
1094466003987	Integrase core domain; Region: rve; pfam00665
1094466003988	Integrase core domain; Region: rve_3; pfam13683
1094466003989	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
1094466003990	malate dehydrogenase; Reviewed; Region: PRK06223
1094466003991	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
1094466003992	NAD(P) binding site [chemical binding]; other site
1094466003993	dimer interface [polypeptide binding]; other site
1094466003994	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1094466003995	substrate binding site [chemical binding]; other site
1094466003996	Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family; Region: GPI-anchored; pfam10342
1094466003997	Endonuclease I; Region: Endonuclease_1; cl01003
1094466003998	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466003999	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1094466004000	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1094466004001	tetramer interface [polypeptide binding]; other site
1094466004002	TPP-binding site [chemical binding]; other site
1094466004003	heterodimer interface [polypeptide binding]; other site
1094466004004	phosphorylation loop region [posttranslational modification]
1094466004005	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1094466004006	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
1094466004007	PYR/PP interface [polypeptide binding]; other site
1094466004008	dimer interface [polypeptide binding]; other site
1094466004009	TPP binding site [chemical binding]; other site
1094466004010	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1094466004011	Ribosomal protein L11 methylase [Translation, ribosomal structure and biogenesis]; Region: PrmA; COG2264
1094466004012	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466004013	S-adenosylmethionine binding site [chemical binding]; other site
1094466004014	ATP-dependent Clp protease adaptor protein ClpS; Region: ClpS; pfam02617
1094466004015	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1094466004016	metal-binding site [ion binding]
1094466004017	Predicted transporter component [General function prediction only]; Region: COG2391
1094466004018	Sulphur transport; Region: Sulf_transp; pfam04143
1094466004019	Domain of unknown function (DUF4341); Region: DUF4341; pfam14241
1094466004020	Sulphur transport; Region: Sulf_transp; pfam04143
1094466004021	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
1094466004022	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1094466004023	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
1094466004024	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1094466004025	dimerization interface [polypeptide binding]; other site
1094466004026	putative DNA binding site [nucleotide binding]; other site
1094466004027	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1094466004028	putative Zn2+ binding site [ion binding]; other site
1094466004029	Coenzyme Q (ubiquinone) biosynthesis protein Coq4; Region: Coq4; cl02093
1094466004030	Protein of unknown function (DUF1361); Region: DUF1361; cl01784
1094466004031	Inner membrane protein CreD; Region: CreD; pfam06123
1094466004032	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1094466004033	putative DNA binding site [nucleotide binding]; other site
1094466004034	dimerization interface [polypeptide binding]; other site
1094466004035	putative Zn2+ binding site [ion binding]; other site
1094466004036	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
1094466004037	putative hydrophobic ligand binding site [chemical binding]; other site
1094466004038	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
1094466004039	putative hydrophobic ligand binding site [chemical binding]; other site
1094466004040	Uncharacterized protein conserved in bacteria (DUF2251); Region: DUF2251; cl01770
1094466004041	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1094466004042	L-fucose transporter; Provisional; Region: PRK10133; cl17665
1094466004043	Saccharopine Dehydrogenase like proteins; Region: SDH_like; cd05199
1094466004044	active site
1094466004045	ligand binding site [chemical binding]; other site
1094466004046	NAD(P) binding site [chemical binding]; other site
1094466004047	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1094466004048	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1094466004049	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1094466004050	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1094466004051	dimerization interface [polypeptide binding]; other site
1094466004052	isocitrate dehydrogenase; Validated; Region: PRK09222
1094466004053	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
1094466004054	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1094466004055	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
1094466004056	Domain of unknown function (DUF897); Region: DUF897; cl01312
1094466004057	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1094466004058	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466004059	active site
1094466004060	phosphorylation site [posttranslational modification]
1094466004061	intermolecular recognition site; other site
1094466004062	dimerization interface [polypeptide binding]; other site
1094466004063	LytTr DNA-binding domain; Region: LytTR; smart00850
1094466004064	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466004065	binding surface
1094466004066	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466004067	TPR motif; other site
1094466004068	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466004069	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466004070	Histidine kinase; Region: His_kinase; pfam06580
1094466004071	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466004072	ATP binding site [chemical binding]; other site
1094466004073	Mg2+ binding site [ion binding]; other site
1094466004074	G-X-G motif; other site
1094466004075	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_3; cd10448
1094466004076	GIY-YIG motif/motif A; other site
1094466004077	putative active site [active]
1094466004078	putative metal binding site [ion binding]; other site
1094466004079	putative transposase OrfB; Reviewed; Region: PHA02517
1094466004080	HTH-like domain; Region: HTH_21; pfam13276
1094466004081	Integrase core domain; Region: rve; pfam00665
1094466004082	Integrase core domain; Region: rve_3; pfam13683
1094466004083	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1094466004084	Transposase; Region: HTH_Tnp_1; cl17663
1094466004085	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1094466004086	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
1094466004087	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
1094466004088	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1094466004089	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
1094466004090	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1094466004091	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466004092	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
1094466004093	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
1094466004094	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1094466004095	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
1094466004096	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1094466004097	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466004098	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
1094466004099	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
1094466004100	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1094466004101	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1094466004102	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466004103	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
1094466004104	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1094466004105	AAA domain; Region: AAA_23; pfam13476
1094466004106	Walker A/P-loop; other site
1094466004107	ATP binding site [chemical binding]; other site
1094466004108	AAA domain; Region: AAA_21; pfam13304
1094466004109	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1094466004110	putative active site [active]
1094466004111	putative metal-binding site [ion binding]; other site
1094466004112	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1094466004113	Part of AAA domain; Region: AAA_19; pfam13245
1094466004114	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; cl19402
1094466004115	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
1094466004116	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
1094466004117	Predicted chitinase [General function prediction only]; Region: COG3179
1094466004118	Transglutaminase-like superfamily; Region: Transglut_core; cl17362
1094466004119	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
1094466004120	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466004121	Walker A motif; other site
1094466004122	ATP binding site [chemical binding]; other site
1094466004123	Helix-turn-helix domain; Region: HTH_17; pfam12728
1094466004124	RteC protein; Region: RteC; pfam09357
1094466004125	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1094466004126	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
1094466004127	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1094466004128	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1094466004129	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466004130	MerT mercuric transport protein; Region: MerT; cl03578
1094466004131	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1094466004132	metal-binding site [ion binding]
1094466004133	DNA / pantothenate metabolizm flavoprotein; Region: DFP; pfam04127
1094466004134	Protein of unknown function, DUF547; Region: DUF547; pfam04784
1094466004135	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
1094466004136	active site
1094466004137	Patatin-like phospholipase; Region: Patatin; pfam01734
1094466004138	active site
1094466004139	nucleophile elbow; other site
1094466004140	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1094466004141	Helix-turn-helix domain; Region: HTH_18; pfam12833
1094466004142	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1094466004143	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1094466004144	active site 1 [active]
1094466004145	dimer interface [polypeptide binding]; other site
1094466004146	hexamer interface [polypeptide binding]; other site
1094466004147	active site 2 [active]
1094466004148	Protein of unknown function (DUF2798); Region: DUF2798; pfam11391
1094466004149	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
1094466004150	YCII-related domain; Region: YCII; cl00999
1094466004151	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1094466004152	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1094466004153	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1094466004154	Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins; Region: PYR_PYL_RCAR_like; cd07821
1094466004155	putative hydrophobic ligand binding site [chemical binding]; other site
1094466004156	protein interface [polypeptide binding]; other site
1094466004157	gate; other site
1094466004158	Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins; Region: PYR_PYL_RCAR_like; cd07821
1094466004159	putative hydrophobic ligand binding site [chemical binding]; other site
1094466004160	protein interface [polypeptide binding]; other site
1094466004161	gate; other site
1094466004162	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1094466004163	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1094466004164	NAD(P) binding site [chemical binding]; other site
1094466004165	active site
1094466004166	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
1094466004167	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1094466004168	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1094466004169	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1094466004170	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1094466004171	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1094466004172	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1094466004173	ligand binding site [chemical binding]; other site
1094466004174	flexible hinge region; other site
1094466004175	Ycf1; Region: Ycf1; pfam05758
1094466004176	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1094466004177	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
1094466004178	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1094466004179	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1094466004180	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
1094466004181	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1094466004182	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1094466004183	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1094466004184	YceI-like domain; Region: YceI; pfam04264
1094466004185	tRNA_anti-like; Region: tRNA_anti-like; pfam12869
1094466004186	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1094466004187	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1094466004188	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
1094466004189	DNA binding residues [nucleotide binding]
1094466004190	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1094466004191	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1094466004192	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1094466004193	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1094466004194	carotene biosynthesis associated membrane protein; Region: crt_membr; TIGR03459
1094466004195	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
1094466004196	Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit substitute of the cellulose synthase complex; Region: CESA_CaSu_A2; cd06437
1094466004197	DXD motif; other site
1094466004198	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1094466004199	Ligand binding site; other site
1094466004200	Putative Catalytic site; other site
1094466004201	DXD motif; other site
1094466004202	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
1094466004203	Protein of unknown function, DUF547; Region: DUF547; pfam04784
1094466004204	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1094466004205	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
1094466004206	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
1094466004207	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
1094466004208	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
1094466004209	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1094466004210	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1094466004211	GT_2_like_a represents a glycosyltransferase family-2 subfamily with unknown function; Region: GT_2_like_a; cd02522
1094466004212	transferase 2, rSAM/selenodomain-associated; Region: glyco_like_mftF; TIGR04283
1094466004213	Probable Catalytic site; other site
1094466004214	Protein of unknown function, DUF547; Region: DUF547; pfam04784
1094466004215	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
1094466004216	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
1094466004217	Phosphate transporter family; Region: PHO4; pfam01384
1094466004218	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466004219	S-adenosylmethionine binding site [chemical binding]; other site
1094466004220	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1094466004221	Purine nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pnp; COG0005
1094466004222	transferase 1, rSAM/selenodomain-associated; Region: glyco_like_cofC; TIGR04282
1094466004223	radical SAM/Cys-rich domain protein; Region: rSAM_SeCys; TIGR04167
1094466004224	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1094466004225	FeS/SAM binding site; other site
1094466004226	Protein of unknown function (DUF3641); Region: DUF3641; pfam12345
1094466004227	alkylhydroperoxidase/carboxymuconolactone decarboxylase family protein; Region: perox_w_seleSAM; TIGR04169
1094466004228	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1094466004229	active site residue [active]
1094466004230	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
1094466004231	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1094466004232	Int/Topo IB signature motif; other site
1094466004233	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
1094466004234	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
1094466004235	GTP cyclohydrolase II; Region: GTP_cyclohydro2; pfam00925
1094466004236	dimerization interface [polypeptide binding]; other site
1094466004237	active site
1094466004238	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1094466004239	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl19192
1094466004240	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1094466004241	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1094466004242	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1094466004243	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1094466004244	Integral membrane undecaprenol kinase and similar enzymes; Region: UDPK_IM_like; cd14265
1094466004245	trimer interface [polypeptide binding]; other site
1094466004246	putative active site [active]
1094466004247	Zn binding site [ion binding]; other site
1094466004248	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1094466004249	dimer interface [polypeptide binding]; other site
1094466004250	catalytic triad [active]
1094466004251	peroxidatic and resolving cysteines [active]
1094466004252	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1094466004253	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1094466004254	active site
1094466004255	23S rRNA-intervening sequence protein; Region: 23S_rRNA_IVP; pfam05635
1094466004256	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1094466004257	oligomerization interface [polypeptide binding]; other site
1094466004258	active site
1094466004259	metal binding site [ion binding]; metal-binding site
1094466004260	Putative lumazine-binding; Region: Lumazine_bd_2; pfam12893
1094466004261	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
1094466004262	Domain of unknown function (DUF389); Region: DUF389; pfam04087
1094466004263	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1094466004264	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1094466004265	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1094466004266	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
1094466004267	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1094466004268	ATP binding site [chemical binding]; other site
1094466004269	Mg++ binding site [ion binding]; other site
1094466004270	motif III; other site
1094466004271	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1094466004272	nucleotide binding region [chemical binding]; other site
1094466004273	ATP-binding site [chemical binding]; other site
1094466004274	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1094466004275	EamA-like transporter family; Region: EamA; pfam00892
1094466004276	Protein of unknown function (DUF2809); Region: DUF2809; pfam10990
1094466004277	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1094466004278	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1094466004279	nucleotide binding site [chemical binding]; other site
1094466004280	NEF interaction site [polypeptide binding]; other site
1094466004281	SBD interface [polypeptide binding]; other site
1094466004282	Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070
1094466004283	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1094466004284	FMN binding site [chemical binding]; other site
1094466004285	substrate binding site [chemical binding]; other site
1094466004286	putative catalytic residue [active]
1094466004287	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1094466004288	ApbE family; Region: ApbE; pfam02424
1094466004289	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
1094466004290	Flavodoxin; Region: Flavodoxin_1; pfam00258
1094466004291	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
1094466004292	FAD binding pocket [chemical binding]; other site
1094466004293	conserved FAD binding motif [chemical binding]; other site
1094466004294	phosphate binding motif [ion binding]; other site
1094466004295	beta-alpha-beta structure motif; other site
1094466004296	NAD binding pocket [chemical binding]; other site
1094466004297	Predicted periplasmic protein (DUF2271); Region: DUF2271; pfam10029
1094466004298	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1094466004299	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1094466004300	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1094466004301	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1094466004302	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1094466004303	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1094466004304	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1094466004305	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1094466004306	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1094466004307	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_1; cd02432
1094466004308	Histidine kinase; Region: His_kinase; pfam06580
1094466004309	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1094466004310	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466004311	active site
1094466004312	phosphorylation site [posttranslational modification]
1094466004313	intermolecular recognition site; other site
1094466004314	dimerization interface [polypeptide binding]; other site
1094466004315	LytTr DNA-binding domain; Region: LytTR; smart00850
1094466004316	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1094466004317	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1094466004318	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1094466004319	active site
1094466004320	HIGH motif; other site
1094466004321	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1094466004322	KMSKS motif; other site
1094466004323	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1094466004324	tRNA binding surface [nucleotide binding]; other site
1094466004325	anticodon binding site; other site
1094466004326	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1094466004327	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
1094466004328	Aspartyl protease; Region: Asp_protease_2; pfam13650
1094466004329	inhibitor binding site; inhibition site
1094466004330	catalytic motif [active]
1094466004331	Catalytic residue [active]
1094466004332	Active site flap [active]
1094466004333	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1094466004334	aspartate aminotransferase; Provisional; Region: PRK07568
1094466004335	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1094466004336	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466004337	homodimer interface [polypeptide binding]; other site
1094466004338	catalytic residue [active]
1094466004339	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1094466004340	putative metal binding site [ion binding]; other site
1094466004341	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
1094466004342	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1094466004343	active site
1094466004344	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1094466004345	SmpB-tmRNA interface; other site
1094466004346	malate:quinone oxidoreductase; Validated; Region: PRK05257
1094466004347	Predicted dehydrogenase [General function prediction only]; Region: COG0579
1094466004348	B-cell receptor-associated protein 31-like; Region: Bap31; cl02219
1094466004349	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
1094466004350	Penicillinase repressor; Region: Penicillinase_R; pfam03965
1094466004351	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1094466004352	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1094466004353	putative substrate translocation pore; other site
1094466004354	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1094466004355	active site
1094466004356	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
1094466004357	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1094466004358	putative ATP binding site [chemical binding]; other site
1094466004359	putative substrate interface [chemical binding]; other site
1094466004360	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
1094466004361	ATP binding site [chemical binding]; other site
1094466004362	active site
1094466004363	phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional; Region: PRK13959
1094466004364	substrate binding site [chemical binding]; other site
1094466004365	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1094466004366	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1094466004367	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1094466004368	PhoH-like protein; Region: PhoH; pfam02562
1094466004369	S-adenosyl-l-methionine hydroxide adenosyltransferase; Region: SAM_adeno_trans; pfam01887
1094466004370	Antibiotic biosynthesis monooxygenase; Region: ABM; pfam03992
1094466004371	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
1094466004372	gliding-associated putative ABC transporter substrate-binding component GldG; Region: GldG; TIGR03521
1094466004373	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
1094466004374	DNA polymerase III subunit beta; Validated; Region: PRK05643
1094466004375	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1094466004376	putative DNA binding surface [nucleotide binding]; other site
1094466004377	dimer interface [polypeptide binding]; other site
1094466004378	beta-clamp/clamp loader binding surface; other site
1094466004379	beta-clamp/translesion DNA polymerase binding surface; other site
1094466004380	Putative catalytic domain of uncharacterized hypothetical proteins closely related to Nuc, , an endonuclease from Salmonella typhimurium; Region: PLDc_Nuc_like_unchar2; cd09174
1094466004381	PLD-like domain; Region: PLDc_2; pfam13091
1094466004382	putative active site [active]
1094466004383	catalytic site [active]
1094466004384	Rhoptry-associated protein 1 (RAP-1); Region: RAP1; pfam07218
1094466004385	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1094466004386	HSP70 interaction site [polypeptide binding]; other site
1094466004387	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1094466004388	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1094466004389	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1094466004390	G1 box; other site
1094466004391	GTP/Mg2+ binding site [chemical binding]; other site
1094466004392	Switch I region; other site
1094466004393	G2 box; other site
1094466004394	Switch II region; other site
1094466004395	G3 box; other site
1094466004396	G4 box; other site
1094466004397	G5 box; other site
1094466004398	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1094466004399	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1094466004400	Active Sites [active]
1094466004401	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
1094466004402	DNA sulfur modification protein DndD; Region: DNA_S_dndD; TIGR03185
1094466004403	AAA domain; Region: AAA_23; pfam13476
1094466004404	Walker A/P-loop; other site
1094466004405	ATP binding site [chemical binding]; other site
1094466004406	Domain of unknown function (DUF1832); Region: DUF1832; cl07463
1094466004407	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466004408	AAA-like domain; Region: AAA_10; pfam12846
1094466004409	Walker A motif; other site
1094466004410	ATP binding site [chemical binding]; other site
1094466004411	Walker B motif; other site
1094466004412	DNA phosphorothioation-associated DGQHR protein 1; Region: DGQHR_dnd_1; TIGR04172
1094466004413	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1094466004414	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1094466004415	catalytic residue [active]
1094466004416	AMP-binding domain protein; Validated; Region: PRK08315
1094466004417	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_2; cd05917
1094466004418	acyl-activating enzyme (AAE) consensus motif; other site
1094466004419	putative AMP binding site [chemical binding]; other site
1094466004420	putative active site [active]
1094466004421	putative CoA binding site [chemical binding]; other site
1094466004422	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1094466004423	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1094466004424	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466004425	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466004426	TPR motif; other site
1094466004427	binding surface
1094466004428	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466004429	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1094466004430	Histidine kinase; Region: HisKA_3; pfam07730
1094466004431	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466004432	ATP binding site [chemical binding]; other site
1094466004433	Mg2+ binding site [ion binding]; other site
1094466004434	G-X-G motif; other site
1094466004435	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1094466004436	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466004437	active site
1094466004438	phosphorylation site [posttranslational modification]
1094466004439	intermolecular recognition site; other site
1094466004440	dimerization interface [polypeptide binding]; other site
1094466004441	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1094466004442	DNA binding residues [nucleotide binding]
1094466004443	dimerization interface [polypeptide binding]; other site
1094466004444	SEC-C motif; Region: SEC-C; cl19389
1094466004445	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466004446	active site
1094466004447	phosphorylation site [posttranslational modification]
1094466004448	intermolecular recognition site; other site
1094466004449	dimerization interface [polypeptide binding]; other site
1094466004450	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1094466004451	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1094466004452	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1094466004453	putative active site [active]
1094466004454	heme pocket [chemical binding]; other site
1094466004455	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466004456	ATP binding site [chemical binding]; other site
1094466004457	Mg2+ binding site [ion binding]; other site
1094466004458	G-X-G motif; other site
1094466004459	Protein of unknown function (DUF541); Region: SIMPL; cl01077
1094466004460	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1094466004461	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1094466004462	ligand binding site [chemical binding]; other site
1094466004463	flexible hinge region; other site
1094466004464	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1094466004465	non-specific DNA interactions [nucleotide binding]; other site
1094466004466	DNA binding site [nucleotide binding]
1094466004467	sequence specific DNA binding site [nucleotide binding]; other site
1094466004468	putative cAMP binding site [chemical binding]; other site
1094466004469	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1094466004470	Rhodanese-like domain; Region: Rhodanese; pfam00581
1094466004471	active site residue [active]
1094466004472	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1094466004473	active site residue [active]
1094466004474	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
1094466004475	DNA polymerase type B, organellar and viral; Region: DNA_pol_B_2; cl19524
1094466004476	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1094466004477	catalytic residues [active]
1094466004478	Protein of unknown function (DUF541); Region: SIMPL; cl01077
1094466004479	Rhomboid family; Region: Rhomboid; pfam01694
1094466004480	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1094466004481	putative acyl-acceptor binding pocket; other site
1094466004482	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1094466004483	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1094466004484	catalytic residue [active]
1094466004485	hypothetical protein; Validated; Region: PRK00029
1094466004486	Domain of unknown function (DU1801); Region: DUF1801; cl17490
1094466004487	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1094466004488	UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Region: alt_bact_glmU; TIGR03991
1094466004489	Sugar nucleotidyl transferase; Region: NTP_transf_4; pfam13562
1094466004490	Uncharacterized proteins, Left-handed parallel beta-Helix (LbH) domain: Members in this group are uncharacterized bacterial proteins containing a LbH domain with multiple turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif...; Region: LbH_unknown; cd05635
1094466004491	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1094466004492	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1094466004493	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1094466004494	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1094466004495	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1094466004496	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1094466004497	Molybdopterin oxidoreductase Fe4S4 domain; Region: Molybdop_Fe4S4; cl19148
1094466004498	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1094466004499	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1094466004500	catalytic residue [active]
1094466004501	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1094466004502	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1094466004503	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1094466004504	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1094466004505	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1094466004506	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1094466004507	active site
1094466004508	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1094466004509	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1094466004510	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1094466004511	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl19158
1094466004512	WxcM-like, C-terminal; Region: FdtA; pfam05523
1094466004513	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1094466004514	This family is most closely related to the GT1 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be...; Region: GT1_amsD_like; cd03820
1094466004515	putative ADP-binding pocket [chemical binding]; other site
1094466004516	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1094466004517	putative active site [active]
1094466004518	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1094466004519	DNA topoisomerase IV subunit A; Provisional; Region: PRK12758
1094466004520	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1094466004521	CAP-like domain; other site
1094466004522	active site
1094466004523	primary dimer interface [polypeptide binding]; other site
1094466004524	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
1094466004525	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466004526	ATP binding site [chemical binding]; other site
1094466004527	Mg2+ binding site [ion binding]; other site
1094466004528	G-X-G motif; other site
1094466004529	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1094466004530	anchoring element; other site
1094466004531	dimer interface [polypeptide binding]; other site
1094466004532	ATP binding site [chemical binding]; other site
1094466004533	TOPRIM_TopoIIA_like: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to Saccharomyces cerevisiae Topoisomerase II. TopoIIA enzymes cut both strands...; Region: TOPRIM_TopoIIA_like; cd01030
1094466004534	active site
1094466004535	putative metal-binding site [ion binding]; other site
1094466004536	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1094466004537	Protein of unknown function (DUF2459); Region: DUF2459; pfam09601
1094466004538	GTP-binding protein YchF; Reviewed; Region: PRK09601
1094466004539	YchF GTPase; Region: YchF; cd01900
1094466004540	G1 box; other site
1094466004541	GTP/Mg2+ binding site [chemical binding]; other site
1094466004542	Switch I region; other site
1094466004543	G2 box; other site
1094466004544	Switch II region; other site
1094466004545	G3 box; other site
1094466004546	G4 box; other site
1094466004547	G5 box; other site
1094466004548	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1094466004549	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
1094466004550	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1094466004551	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
1094466004552	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1094466004553	catalytic residue [active]
1094466004554	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1094466004555	Phosphoglycerate dehydrogenase (PGDH) NAD-binding and catalytic domains; Region: PGDH_2; cd05303
1094466004556	putative ligand binding site [chemical binding]; other site
1094466004557	NAD binding site [chemical binding]; other site
1094466004558	dimerization interface [polypeptide binding]; other site
1094466004559	catalytic site [active]
1094466004560	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1094466004561	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1094466004562	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1094466004563	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1094466004564	Putative esterase; Region: Esterase; pfam00756
1094466004565	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1094466004566	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
1094466004567	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466004568	ATP binding site [chemical binding]; other site
1094466004569	Mg2+ binding site [ion binding]; other site
1094466004570	G-X-G motif; other site
1094466004571	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1094466004572	anchoring element; other site
1094466004573	dimer interface [polypeptide binding]; other site
1094466004574	ATP binding site [chemical binding]; other site
1094466004575	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1094466004576	active site
1094466004577	putative metal-binding site [ion binding]; other site
1094466004578	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1094466004579	asparagine synthetase B; Provisional; Region: asnB; PRK09431
1094466004580	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1094466004581	active site
1094466004582	dimer interface [polypeptide binding]; other site
1094466004583	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1094466004584	Ligand Binding Site [chemical binding]; other site
1094466004585	Molecular Tunnel; other site
1094466004586	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1094466004587	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466004588	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1094466004589	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
1094466004590	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466004591	binding surface
1094466004592	TPR motif; other site
1094466004593	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466004594	binding surface
1094466004595	TPR motif; other site
1094466004596	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
1094466004597	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466004598	binding surface
1094466004599	TPR motif; other site
1094466004600	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
1094466004601	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466004602	binding surface
1094466004603	TPR motif; other site
1094466004604	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1094466004605	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
1094466004606	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1094466004607	Walker A/P-loop; other site
1094466004608	ATP binding site [chemical binding]; other site
1094466004609	Q-loop/lid; other site
1094466004610	ABC transporter signature motif; other site
1094466004611	Walker B; other site
1094466004612	D-loop; other site
1094466004613	H-loop/switch region; other site
1094466004614	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
1094466004615	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1094466004616	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1094466004617	Ligand binding site; other site
1094466004618	Putative Catalytic site; other site
1094466004619	DXD motif; other site
1094466004620	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
1094466004621	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
1094466004622	active site
1094466004623	substrate binding site [chemical binding]; other site
1094466004624	metal binding site [ion binding]; metal-binding site
1094466004625	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1094466004626	lipid A export permease/ATP-binding protein MsbA; Region: MsbA_lipidA; TIGR02203
1094466004627	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1094466004628	Walker A/P-loop; other site
1094466004629	ATP binding site [chemical binding]; other site
1094466004630	Q-loop/lid; other site
1094466004631	ABC transporter signature motif; other site
1094466004632	Walker B; other site
1094466004633	D-loop; other site
1094466004634	H-loop/switch region; other site
1094466004635	Protein of unknown function (DUF2971); Region: DUF2971; pfam11185
1094466004636	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466004637	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1094466004638	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1094466004639	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466004640	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1094466004641	Peptidase family M23; Region: Peptidase_M23; pfam01551
1094466004642	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1094466004643	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1094466004644	Polysaccharide biosynthesis C-terminal domain; Region: Polysacc_synt_C; pfam14667
1094466004645	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1094466004646	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1094466004647	Nucleotidyl transferase of unknown function (DUF2204); Region: DUF2204; cl17690
1094466004648	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl19158
1094466004649	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; pfam13557
1094466004650	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1094466004651	Coenzyme A binding pocket [chemical binding]; other site
1094466004652	YbaB/EbfC DNA-binding family; Region: YbaB_DNA_bd; cl00494
1094466004653	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1094466004654	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466004655	active site
1094466004656	phosphorylation site [posttranslational modification]
1094466004657	intermolecular recognition site; other site
1094466004658	dimerization interface [polypeptide binding]; other site
1094466004659	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
1094466004660	DNA binding site [nucleotide binding]
1094466004661	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1094466004662	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1094466004663	dimer interface [polypeptide binding]; other site
1094466004664	phosphorylation site [posttranslational modification]
1094466004665	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466004666	ATP binding site [chemical binding]; other site
1094466004667	Mg2+ binding site [ion binding]; other site
1094466004668	G-X-G motif; other site
1094466004669	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1094466004670	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1094466004671	CoA-binding site [chemical binding]; other site
1094466004672	ATP-binding [chemical binding]; other site
1094466004673	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1094466004674	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1094466004675	active site
1094466004676	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466004677	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1094466004678	Interdomain contacts; other site
1094466004679	Cytokine receptor motif; other site
1094466004680	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466004681	trans-2-enoyl-CoA reductase; Provisional; Region: PRK13656
1094466004682	NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Region: Eno-Rase_NADH_b; pfam12242
1094466004683	Trans-2-enoyl-CoA reductase catalytic region; Region: Enoyl_reductase; pfam12241
1094466004684	Enoyl reductase FAD binding domain; Region: Eno-Rase_FAD_bd; pfam07055
1094466004685	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1094466004686	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1094466004687	Walker A/P-loop; other site
1094466004688	ATP binding site [chemical binding]; other site
1094466004689	Q-loop/lid; other site
1094466004690	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1094466004691	ABC transporter signature motif; other site
1094466004692	Walker B; other site
1094466004693	D-loop; other site
1094466004694	H-loop/switch region; other site
1094466004695	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1094466004696	Flavoprotein; Region: Flavoprotein; cl19190
1094466004697	DNA / pantothenate metabolizm flavoprotein; Region: DFP; pfam04127
1094466004698	RNA polymerase Rpb6; Region: RNA_pol_Rpb6; pfam01192
1094466004699	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
1094466004700	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1094466004701	dimer interface [polypeptide binding]; other site
1094466004702	active site
1094466004703	catalytic residue [active]
1094466004704	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1094466004705	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1094466004706	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1094466004707	active site
1094466004708	metal binding site [ion binding]; metal-binding site
1094466004709	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1094466004710	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1094466004711	nucleotide binding pocket [chemical binding]; other site
1094466004712	K-X-D-G motif; other site
1094466004713	catalytic site [active]
1094466004714	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1094466004715	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1094466004716	Helix-hairpin-helix motif; Region: HHH_2; pfam12826
1094466004717	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1094466004718	Dimer interface [polypeptide binding]; other site
1094466004719	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1094466004720	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1094466004721	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1094466004722	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1094466004723	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1094466004724	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1094466004725	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466004726	active site
1094466004727	phosphorylation site [posttranslational modification]
1094466004728	intermolecular recognition site; other site
1094466004729	dimerization interface [polypeptide binding]; other site
1094466004730	LytTr DNA-binding domain; Region: LytTR; smart00850
1094466004731	primosome assembly protein PriA; Validated; Region: PRK05580
1094466004732	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1094466004733	ATP binding site [chemical binding]; other site
1094466004734	putative Mg++ binding site [ion binding]; other site
1094466004735	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1094466004736	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GpsA; COG0240
1094466004737	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1094466004738	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1094466004739	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1094466004740	dimer interface [polypeptide binding]; other site
1094466004741	active site
1094466004742	metal binding site [ion binding]; metal-binding site
1094466004743	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1094466004744	active site
1094466004745	(T/H)XGH motif; other site
1094466004746	Guanylate kinase; Region: Guanylate_kin; pfam00625
1094466004747	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1094466004748	catalytic site [active]
1094466004749	G-X2-G-X-G-K; other site
1094466004750	hypothetical protein; Provisional; Region: PRK11820
1094466004751	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1094466004752	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1094466004753	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1094466004754	EamA-like transporter family; Region: EamA; pfam00892
1094466004755	EamA-like transporter family; Region: EamA; pfam00892
1094466004756	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1094466004757	DinB superfamily; Region: DinB_2; pfam12867
1094466004758	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1094466004759	active site
1094466004760	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
1094466004761	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1094466004762	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1094466004763	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1094466004764	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466004765	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466004766	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1094466004767	YCII-related domain; Region: YCII; cl00999
1094466004768	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
1094466004769	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
1094466004770	Uncharacterized protein conserved in bacteria (DUF2200); Region: DUF2200; pfam09966
1094466004771	Protein of unknown function (DUF2975); Region: DUF2975; pfam11188
1094466004772	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1094466004773	salt bridge; other site
1094466004774	non-specific DNA binding site [nucleotide binding]; other site
1094466004775	sequence-specific DNA binding site [nucleotide binding]; other site
1094466004776	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1094466004777	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1094466004778	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466004779	Walker A/P-loop; other site
1094466004780	ATP binding site [chemical binding]; other site
1094466004781	Q-loop/lid; other site
1094466004782	ABC transporter signature motif; other site
1094466004783	Walker B; other site
1094466004784	D-loop; other site
1094466004785	H-loop/switch region; other site
1094466004786	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1094466004787	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1094466004788	Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]; Region: CrcB; COG0239
1094466004789	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
1094466004790	DHH family; Region: DHH; pfam01368
1094466004791	DHHA1 domain; Region: DHHA1; pfam02272
1094466004792	peptidyl-prolyl isomerase, gliding motility-associated; Region: ppisom_GldI; TIGR03516
1094466004793	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1094466004794	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1094466004795	active site
1094466004796	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1094466004797	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1094466004798	active site
1094466004799	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
1094466004800	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1094466004801	GTP-binding protein TypA/BipA; Region: TypA_BipA; TIGR01394
1094466004802	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1094466004803	G1 box; other site
1094466004804	putative GEF interaction site [polypeptide binding]; other site
1094466004805	GTP/Mg2+ binding site [chemical binding]; other site
1094466004806	Switch I region; other site
1094466004807	G2 box; other site
1094466004808	G3 box; other site
1094466004809	Switch II region; other site
1094466004810	G4 box; other site
1094466004811	G5 box; other site
1094466004812	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1094466004813	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1094466004814	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1094466004815	prolyl-tRNA synthetase; Provisional; Region: PRK08661
1094466004816	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
1094466004817	dimer interface [polypeptide binding]; other site
1094466004818	motif 1; other site
1094466004819	active site
1094466004820	motif 2; other site
1094466004821	motif 3; other site
1094466004822	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
1094466004823	anticodon binding site; other site
1094466004824	zinc-binding site [ion binding]; other site
1094466004825	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
1094466004826	ribosomal protein S12 methylthiotransferase RimO; Region: TIGR01125
1094466004827	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1094466004828	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1094466004829	FeS/SAM binding site; other site
1094466004830	MarR family; Region: MarR_2; cl17246
1094466004831	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1094466004832	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1094466004833	HlyD family secretion protein; Region: HlyD_3; pfam13437
1094466004834	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1094466004835	MMPL family; Region: MMPL; cl14618
1094466004836	MMPL family; Region: MMPL; cl14618
1094466004837	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1094466004838	Outer membrane efflux protein; Region: OEP; pfam02321
1094466004839	Outer membrane efflux protein; Region: OEP; pfam02321
1094466004840	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2841
1094466004841	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
1094466004842	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1094466004843	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1094466004844	active site residue [active]
1094466004845	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1094466004846	active site residue [active]
1094466004847	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
1094466004848	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; cl19172
1094466004849	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; cl19172
1094466004850	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1094466004851	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1094466004852	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1094466004853	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1094466004854	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1094466004855	carboxyltransferase (CT) interaction site; other site
1094466004856	biotinylation site [posttranslational modification]; other site
1094466004857	CHASE4 domain; Region: CHASE4; cl01308
1094466004858	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1094466004859	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1094466004860	dimer interface [polypeptide binding]; other site
1094466004861	phosphorylation site [posttranslational modification]
1094466004862	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466004863	ATP binding site [chemical binding]; other site
1094466004864	Mg2+ binding site [ion binding]; other site
1094466004865	G-X-G motif; other site
1094466004866	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466004867	active site
1094466004868	phosphorylation site [posttranslational modification]
1094466004869	intermolecular recognition site; other site
1094466004870	dimerization interface [polypeptide binding]; other site
1094466004871	B12 binding domain; Region: B12-binding; pfam02310
1094466004872	B12 binding site [chemical binding]; other site
1094466004873	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1094466004874	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1094466004875	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1094466004876	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1094466004877	Uncharacterized protein conserved in bacteria (DUF2317); Region: DUF2317; pfam10079
1094466004878	Uncharacterized conserved protein [Function unknown]; Region: COG1262
1094466004879	Sulfatase-modifying factor enzyme 1; Region: FGE-sulfatase; cl19582
1094466004880	Nucleoside diphosphate kinase; Region: NDK; pfam00334
1094466004881	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1094466004882	active site
1094466004883	multimer interface [polypeptide binding]; other site
1094466004884	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1094466004885	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1094466004886	non-specific DNA binding site [nucleotide binding]; other site
1094466004887	salt bridge; other site
1094466004888	sequence-specific DNA binding site [nucleotide binding]; other site
1094466004889	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1094466004890	active site
1094466004891	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1094466004892	tetramer interface [polypeptide binding]; other site
1094466004893	active site
1094466004894	Mg2+/Mn2+ binding site [ion binding]; other site
1094466004895	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1094466004896	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1094466004897	N-terminal plug; other site
1094466004898	ligand-binding site [chemical binding]; other site
1094466004899	Protein of unknown function (DUF721); Region: DUF721; pfam05258
1094466004900	Lipocalin-like domain; Region: Lipocalin_4; pfam13648
1094466004901	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1094466004902	ATP-binding site [chemical binding]; other site
1094466004903	Sugar specificity; other site
1094466004904	Pyrimidine base specificity; other site
1094466004905	Septum formation initiator; Region: DivIC; cl17659
1094466004906	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Beta subunit-like subfamily; contains bacterial proteins similar to the beta subunit of MCMs from Propionbacterium shermanni and Streptomyces cinnamonensis, which are alpha/beta...; Region: MM_CoA_mutase_beta; cd03677
1094466004907	heterodimer interface [polypeptide binding]; other site
1094466004908	substrate interaction site [chemical binding]; other site
1094466004909	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
1094466004910	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
1094466004911	active site
1094466004912	substrate binding site [chemical binding]; other site
1094466004913	coenzyme B12 binding site [chemical binding]; other site
1094466004914	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
1094466004915	B12 binding site [chemical binding]; other site
1094466004916	cobalt ligand [ion binding]; other site
1094466004917	methionine aminotransferase; Validated; Region: PRK09082
1094466004918	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1094466004919	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466004920	homodimer interface [polypeptide binding]; other site
1094466004921	catalytic residue [active]
1094466004922	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1094466004923	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1094466004924	active site
1094466004925	DNA binding site [nucleotide binding]
1094466004926	Int/Topo IB signature motif; other site
1094466004927	Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its homologs; Region: GIY-YIG_SLX1_like; cd10449
1094466004928	GIY-YIG motif/motif A; other site
1094466004929	putative active site [active]
1094466004930	putative metal binding site [ion binding]; other site
1094466004931	Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its homologs; Region: GIY-YIG_SLX1_like; cd10449
1094466004932	GIY-YIG motif/motif A; other site
1094466004933	putative active site [active]
1094466004934	putative metal binding site [ion binding]; other site
1094466004935	Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its homologs; Region: GIY-YIG_SLX1_like; cd10449
1094466004936	GIY-YIG motif/motif A; other site
1094466004937	putative active site [active]
1094466004938	putative metal binding site [ion binding]; other site
1094466004939	Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its homologs; Region: GIY-YIG_SLX1_like; cd10449
1094466004940	GIY-YIG motif/motif A; other site
1094466004941	putative active site [active]
1094466004942	putative metal binding site [ion binding]; other site
1094466004943	bacillithiol biosynthesis deacetylase BshB1; Region: thiol_BshB1; TIGR04001
1094466004944	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1094466004945	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1094466004946	CoenzymeA binding site [chemical binding]; other site
1094466004947	subunit interaction site [polypeptide binding]; other site
1094466004948	PHB binding site; other site
1094466004949	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1094466004950	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
1094466004951	dimerization interface [polypeptide binding]; other site
1094466004952	ATP binding site [chemical binding]; other site
1094466004953	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
1094466004954	dimerization interface [polypeptide binding]; other site
1094466004955	ATP binding site [chemical binding]; other site
1094466004956	CobB/CobQ-like glutamine amidotransferase domain; Region: GATase_5; pfam13507
1094466004957	conserved cys residue [active]
1094466004958	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466004959	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466004960	binding surface
1094466004961	TPR motif; other site
1094466004962	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1094466004963	dimer interface [polypeptide binding]; other site
1094466004964	phosphorylation site [posttranslational modification]
1094466004965	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466004966	ATP binding site [chemical binding]; other site
1094466004967	Mg2+ binding site [ion binding]; other site
1094466004968	G-X-G motif; other site
1094466004969	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466004970	active site
1094466004971	phosphorylation site [posttranslational modification]
1094466004972	intermolecular recognition site; other site
1094466004973	dimerization interface [polypeptide binding]; other site
1094466004974	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1094466004975	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1094466004976	ABC transporter; Region: ABC_tran_2; pfam12848
1094466004977	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1094466004978	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; cl19912
1094466004979	DNA polymerase III, delta subunit; Region: holA; TIGR01128
1094466004980	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
1094466004981	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1094466004982	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
1094466004983	Probable Catalytic site; other site
1094466004984	metal-binding site
1094466004985	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
1094466004986	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466004987	ligand binding site [chemical binding]; other site
1094466004988	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1094466004989	putative active site [active]
1094466004990	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466004991	S-adenosylmethionine binding site [chemical binding]; other site
1094466004992	helicase 45; Provisional; Region: PTZ00424
1094466004993	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1094466004994	ATP binding site [chemical binding]; other site
1094466004995	Mg++ binding site [ion binding]; other site
1094466004996	motif III; other site
1094466004997	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1094466004998	nucleotide binding region [chemical binding]; other site
1094466004999	ATP-binding site [chemical binding]; other site
1094466005000	von Willebrand factor type A domain; Region: VWA_2; pfam13519
1094466005001	dihydroorotase; Validated; Region: pyrC; PRK09357
1094466005002	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1094466005003	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
1094466005004	active site
1094466005005	Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144
1094466005006	Predicted esterase [General function prediction only]; Region: COG0400
1094466005007	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1094466005008	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1094466005009	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1094466005010	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1094466005011	catalytic triad [active]
1094466005012	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1094466005013	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1094466005014	minor groove reading motif; other site
1094466005015	helix-hairpin-helix signature motif; other site
1094466005016	substrate binding pocket [chemical binding]; other site
1094466005017	active site
1094466005018	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1094466005019	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1094466005020	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1094466005021	DNA binding residues [nucleotide binding]
1094466005022	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1094466005023	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1094466005024	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466005025	ABC transporter signature motif; other site
1094466005026	Walker B; other site
1094466005027	D-loop; other site
1094466005028	H-loop/switch region; other site
1094466005029	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466005030	Walker A/P-loop; other site
1094466005031	ATP binding site [chemical binding]; other site
1094466005032	Q-loop/lid; other site
1094466005033	ABC transporter signature motif; other site
1094466005034	Walker B; other site
1094466005035	D-loop; other site
1094466005036	H-loop/switch region; other site
1094466005037	excinuclease ABC subunit B; Provisional; Region: PRK05298
1094466005038	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1094466005039	ATP binding site [chemical binding]; other site
1094466005040	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1094466005041	nucleotide binding region [chemical binding]; other site
1094466005042	ATP-binding site [chemical binding]; other site
1094466005043	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1094466005044	UvrB/uvrC motif; Region: UVR; pfam02151
1094466005045	tellurium resistance terB-like protein; Region: terB_like; cd07177
1094466005046	metal binding site [ion binding]; metal-binding site
1094466005047	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1094466005048	Putative esterase; Region: Esterase; pfam00756
1094466005049	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1094466005050	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1094466005051	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1094466005052	dimer interface [polypeptide binding]; other site
1094466005053	tetramer interface [polypeptide binding]; other site
1094466005054	PYR/PP interface [polypeptide binding]; other site
1094466005055	TPP binding site [chemical binding]; other site
1094466005056	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1094466005057	TPP-binding site; other site
1094466005058	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1094466005059	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1094466005060	Coenzyme A binding pocket [chemical binding]; other site
1094466005061	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1094466005062	catalytic residues [active]
1094466005063	dimer interface [polypeptide binding]; other site
1094466005064	ResB-like family; Region: ResB; cl09125
1094466005065	ResB-like family; Region: ResB; cl09125
1094466005066	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
1094466005067	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
1094466005068	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1094466005069	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
1094466005070	FtsH Extracellular; Region: FtsH_ext; pfam06480
1094466005071	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1094466005072	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466005073	Walker A motif; other site
1094466005074	ATP binding site [chemical binding]; other site
1094466005075	Walker B motif; other site
1094466005076	arginine finger; other site
1094466005077	Peptidase family M41; Region: Peptidase_M41; pfam01434
1094466005078	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; cl00674
1094466005079	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1094466005080	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
1094466005081	Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a...; Region: ACBP; cl00221
1094466005082	acyl-CoA binding pocket [chemical binding]; other site
1094466005083	CoA binding site [chemical binding]; other site
1094466005084	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1094466005085	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1094466005086	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1094466005087	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
1094466005088	Arginase-like and histone-like hydrolases; Region: Arginase_HDAC; cl17011
1094466005089	active site
1094466005090	metal binding site [ion binding]; metal-binding site
1094466005091	Cell division protein ZapA; Region: ZapA; pfam05164
1094466005092	phosphodiesterase; Provisional; Region: PRK12704
1094466005093	KH domain; Region: KH_1; pfam00013
1094466005094	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1094466005095	Zn2+ binding site [ion binding]; other site
1094466005096	Mg2+ binding site [ion binding]; other site
1094466005097	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1094466005098	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1094466005099	SRP54-type protein, GTPase domain; Region: SRP54; smart00962
1094466005100	Domain of unknown function (DUF4295); Region: DUF4295; pfam14128
1094466005101	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1094466005102	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1094466005103	competence damage-inducible protein A; Provisional; Region: PRK00549
1094466005104	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1094466005105	putative MPT binding site; other site
1094466005106	Competence-damaged protein; Region: CinA; pfam02464
1094466005107	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1094466005108	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1094466005109	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1094466005110	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1094466005111	active site
1094466005112	catalytic site [active]
1094466005113	substrate binding site [chemical binding]; other site
1094466005114	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
1094466005115	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1094466005116	E3 interaction surface; other site
1094466005117	lipoyl attachment site [posttranslational modification]; other site
1094466005118	e3 binding domain; Region: E3_binding; pfam02817
1094466005119	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1094466005120	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1094466005121	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
1094466005122	Probable Catalytic site; other site
1094466005123	metal-binding site
1094466005124	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1094466005125	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1094466005126	ABC transporter; Region: ABC_tran_2; pfam12848
1094466005127	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1094466005128	Methyltransferase domain; Region: Methyltransf_24; pfam13578
1094466005129	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1094466005130	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1094466005131	Walker A/P-loop; other site
1094466005132	ATP binding site [chemical binding]; other site
1094466005133	Q-loop/lid; other site
1094466005134	ABC transporter signature motif; other site
1094466005135	Walker B; other site
1094466005136	D-loop; other site
1094466005137	H-loop/switch region; other site
1094466005138	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1094466005139	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1094466005140	Diaminopimelate epimerase; Region: DAP_epimerase; cl19724
1094466005141	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
1094466005142	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1094466005143	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1094466005144	protein binding site [polypeptide binding]; other site
1094466005145	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1094466005146	protein binding site [polypeptide binding]; other site
1094466005147	glyceraldehyde-3-phosphate dehydrogenase; Reviewed; Region: PRK08289
1094466005148	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1094466005149	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1094466005150	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_1; cd07818
1094466005151	putative hydrophobic ligand binding site [chemical binding]; other site
1094466005152	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
1094466005153	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1094466005154	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1094466005155	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1094466005156	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1094466005157	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1094466005158	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1094466005159	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1094466005160	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1094466005161	NlpC/P60 family; Region: NLPC_P60; pfam00877
1094466005162	aconitate hydratase, mitochondrial; Region: aconitase_mito; TIGR01340
1094466005163	Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: AcnA_Mitochondrial; cd01584
1094466005164	substrate binding site [chemical binding]; other site
1094466005165	ligand binding site [chemical binding]; other site
1094466005166	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
1094466005167	substrate binding site [chemical binding]; other site
1094466005168	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1094466005169	Aconitate B N-terminal domain; Region: Aconitase_B_N; pfam11791
1094466005170	Aconitate hydratase 2 N-terminus; Region: Aconitase_2_N; pfam06434
1094466005171	substrate binding site [chemical binding]; other site
1094466005172	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
1094466005173	substrate binding site [chemical binding]; other site
1094466005174	ligand binding site [chemical binding]; other site
1094466005175	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1094466005176	Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144
1094466005177	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1094466005178	MoxR-like ATPases [General function prediction only]; Region: COG0714
1094466005179	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466005180	Walker A motif; other site
1094466005181	ATP binding site [chemical binding]; other site
1094466005182	Walker B motif; other site
1094466005183	arginine finger; other site
1094466005184	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1094466005185	SurA N-terminal domain; Region: SurA_N; pfam09312
1094466005186	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1094466005187	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1094466005188	peptidyl-prolyl cis-trans isomerase, EpsD family; Region: cis_trans_EpsD; TIGR02925
1094466005189	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1094466005190	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1094466005191	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1094466005192	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190
1094466005193	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1094466005194	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1094466005195	homodimer interface [polypeptide binding]; other site
1094466005196	NADP binding site [chemical binding]; other site
1094466005197	substrate binding site [chemical binding]; other site
1094466005198	signal recognition particle protein; Provisional; Region: PRK10867
1094466005199	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1094466005200	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1094466005201	P loop; other site
1094466005202	GTP binding site [chemical binding]; other site
1094466005203	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1094466005204	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
1094466005205	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1094466005206	MMPL family; Region: MMPL; cl14618
1094466005207	Cytochrome oxidase subunit II; Region: Cyto_ox_2; cl12219
1094466005208	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1094466005209	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1094466005210	HlyD family secretion protein; Region: HlyD_3; pfam13437
1094466005211	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1094466005212	Outer membrane efflux protein; Region: OEP; pfam02321
1094466005213	Outer membrane efflux protein; Region: OEP; pfam02321
1094466005214	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1094466005215	catalytic residues [active]
1094466005216	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1094466005217	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1094466005218	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1094466005219	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1094466005220	active site
1094466005221	oxyanion hole [active]
1094466005222	catalytic triad [active]
1094466005223	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1094466005224	active site
1094466005225	oxyanion hole [active]
1094466005226	catalytic triad [active]
1094466005227	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
1094466005228	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
1094466005229	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1094466005230	active site
1094466005231	nucleotide binding site [chemical binding]; other site
1094466005232	HIGH motif; other site
1094466005233	KMSKS motif; other site
1094466005234	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1094466005235	tRNA binding surface [nucleotide binding]; other site
1094466005236	anticodon binding site; other site
1094466005237	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466005238	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1094466005239	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1094466005240	Outer membrane protein beta-barrel family; Region: OMP_b-brl_3; pfam14905
1094466005241	DinB family; Region: DinB; cl17821
1094466005242	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1094466005243	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1094466005244	dimer interface [polypeptide binding]; other site
1094466005245	active site
1094466005246	CoA binding pocket [chemical binding]; other site
1094466005247	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
1094466005248	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
1094466005249	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1094466005250	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466005251	Walker A/P-loop; other site
1094466005252	ATP binding site [chemical binding]; other site
1094466005253	Q-loop/lid; other site
1094466005254	ABC transporter signature motif; other site
1094466005255	Walker B; other site
1094466005256	D-loop; other site
1094466005257	H-loop/switch region; other site
1094466005258	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1094466005259	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466005260	ligand binding site [chemical binding]; other site
1094466005261	heat shock protein 90; Provisional; Region: PRK05218
1094466005262	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466005263	ATP binding site [chemical binding]; other site
1094466005264	Mg2+ binding site [ion binding]; other site
1094466005265	G-X-G motif; other site
1094466005266	Hsp90 protein; Region: HSP90; pfam00183
1094466005267	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1094466005268	DNA-binding site [nucleotide binding]; DNA binding site
1094466005269	RNA-binding motif; other site
1094466005270	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1094466005271	RNA binding site [nucleotide binding]; other site
1094466005272	Protein of unknown function (DUF2721); Region: DUF2721; pfam11026
1094466005273	Outer membrane lipoprotein Slp family; Region: Slp; cl01164
1094466005274	L,D-transpeptidase catalytic domain; Region: YkuD_2; pfam13645
1094466005275	Protein of unknown function (DUF1800); Region: DUF1800; cl19889
1094466005276	Protein of unknown function (DUF1501); Region: DUF1501; cl19855
1094466005277	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1094466005278	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1094466005279	amphipathic channel; other site
1094466005280	Asn-Pro-Ala signature motifs; other site
1094466005281	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_2; pfam13532
1094466005282	Protein of unknown function (DUF2805); Region: DUF2805; pfam10985
1094466005283	Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975
1094466005284	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1094466005285	M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299
1094466005286	Zn binding site [ion binding]; other site
1094466005287	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1094466005288	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
1094466005289	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1094466005290	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1094466005291	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1094466005292	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
1094466005293	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl19057
1094466005294	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1094466005295	active site
1094466005296	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
1094466005297	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1094466005298	active site
1094466005299	metal binding site [ion binding]; metal-binding site
1094466005300	nudix motif; other site
1094466005301	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1094466005302	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1094466005303	P-loop; other site
1094466005304	Magnesium ion binding site [ion binding]; other site
1094466005305	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1094466005306	ParB-like nuclease domain; Region: ParBc; pfam02195
1094466005307	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1094466005308	non-specific DNA binding site [nucleotide binding]; other site
1094466005309	salt bridge; other site
1094466005310	sequence-specific DNA binding site [nucleotide binding]; other site
1094466005311	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1094466005312	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1094466005313	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1094466005314	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1094466005315	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1094466005316	Catalytic site [active]
1094466005317	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1094466005318	WbqC-like protein family; Region: WbqC; pfam08889
1094466005319	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2; Region: EEP-2; cd09084
1094466005320	putative catalytic site [active]
1094466005321	putative metal binding site [ion binding]; other site
1094466005322	putative phosphate binding site [ion binding]; other site
1094466005323	Rhomboid family; Region: Rhomboid; cl11446
1094466005324	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1094466005325	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1094466005326	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466005327	ATP binding site [chemical binding]; other site
1094466005328	Mg2+ binding site [ion binding]; other site
1094466005329	G-X-G motif; other site
1094466005330	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
1094466005331	ATP binding site [chemical binding]; other site
1094466005332	MutL C terminal dimerisation domain; Region: MutL_C; smart00853
1094466005333	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1094466005334	homopentamer interface [polypeptide binding]; other site
1094466005335	active site
1094466005336	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466005337	binding surface
1094466005338	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1094466005339	TPR motif; other site
1094466005340	recombination protein F; Reviewed; Region: recF; PRK00064
1094466005341	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466005342	Walker A/P-loop; other site
1094466005343	ATP binding site [chemical binding]; other site
1094466005344	Q-loop/lid; other site
1094466005345	ABC transporter signature motif; other site
1094466005346	Walker B; other site
1094466005347	D-loop; other site
1094466005348	H-loop/switch region; other site
1094466005349	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1094466005350	active site residue [active]
1094466005351	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1094466005352	catalytic residues [active]
1094466005353	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1094466005354	FAD binding domain; Region: FAD_binding_4; pfam01565
1094466005355	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1094466005356	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1094466005357	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1094466005358	active site
1094466005359	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1094466005360	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1094466005361	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1094466005362	DNA binding residues [nucleotide binding]
1094466005363	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1094466005364	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1094466005365	putative substrate translocation pore; other site
1094466005366	Gram-negative bacterial TonB protein C-terminal; Region: TonB_C; cl10048
1094466005367	lipoyl synthase; Provisional; Region: PRK05481
1094466005368	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1094466005369	FeS/SAM binding site; other site
1094466005370	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1094466005371	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
1094466005372	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1094466005373	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466005374	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466005375	TPR motif; other site
1094466005376	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466005377	binding surface
1094466005378	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466005379	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466005380	binding surface
1094466005381	TPR motif; other site
1094466005382	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1094466005383	dimer interface [polypeptide binding]; other site
1094466005384	phosphorylation site [posttranslational modification]
1094466005385	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466005386	ATP binding site [chemical binding]; other site
1094466005387	Mg2+ binding site [ion binding]; other site
1094466005388	G-X-G motif; other site
1094466005389	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466005390	active site
1094466005391	phosphorylation site [posttranslational modification]
1094466005392	intermolecular recognition site; other site
1094466005393	dimerization interface [polypeptide binding]; other site
1094466005394	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1094466005395	Purine nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pnp; COG0005
1094466005396	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; pfam02606
1094466005397	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1094466005398	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1094466005399	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
1094466005400	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
1094466005401	Rotavirus VP2 protein; Region: Rota_VP2; pfam05087
1094466005402	Putative zinc ribbon domain; Region: DUF164; pfam02591
1094466005403	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1094466005404	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1094466005405	RNA binding surface [nucleotide binding]; other site
1094466005406	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1094466005407	probable active site [active]
1094466005408	SPASM domain peptide maturase, grasp-with-spasm system; Region: SPASM_w_grasp; TIGR04193
1094466005409	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1094466005410	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1094466005411	natural product precursor, GG-Bacteroidales family; Region: GG_sam_targ_CFB; TIGR04149
1094466005412	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1094466005413	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1094466005414	non-specific DNA binding site [nucleotide binding]; other site
1094466005415	salt bridge; other site
1094466005416	sequence-specific DNA binding site [nucleotide binding]; other site
1094466005417	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1094466005418	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1094466005419	Coenzyme A binding pocket [chemical binding]; other site
1094466005420	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466005421	Protein of unknown function (DUF3467); Region: DUF3467; pfam11950
1094466005422	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
1094466005423	Largest subunit (beta') of bacterial DNA-dependent RNA polymerase (RNAP), N-terminal domain; Region: RNAP_beta'_N; cd01609
1094466005424	beta and beta' interface [polypeptide binding]; other site
1094466005425	beta' and sigma factor interface [polypeptide binding]; other site
1094466005426	Zn-binding [ion binding]; other site
1094466005427	active site region [active]
1094466005428	catalytic site [active]
1094466005429	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1094466005430	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
1094466005431	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1094466005432	cleft; other site
1094466005433	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1094466005434	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1094466005435	G-loop; other site
1094466005436	Rpb1 - Rpb5 interaction site [polypeptide binding]; other site
1094466005437	DNA binding site [nucleotide binding]
1094466005438	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1094466005439	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1094466005440	RPB12 interaction site [polypeptide binding]; other site
1094466005441	RNA polymerase beta subunit; Region: RNA_pol_Rpb2_1; cl19478
1094466005442	RPB1 interaction site [polypeptide binding]; other site
1094466005443	RNA polymerase beta subunit external 1 domain; Region: RNA_pol_Rpb2_45; pfam10385
1094466005444	RPB10 interaction site [polypeptide binding]; other site
1094466005445	RPB11 interaction site [polypeptide binding]; other site
1094466005446	RPB3 interaction site [polypeptide binding]; other site
1094466005447	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1094466005448	core dimer interface [polypeptide binding]; other site
1094466005449	peripheral dimer interface [polypeptide binding]; other site
1094466005450	L10 interface [polypeptide binding]; other site
1094466005451	L11 interface [polypeptide binding]; other site
1094466005452	putative EF-Tu interaction site [polypeptide binding]; other site
1094466005453	putative EF-G interaction site [polypeptide binding]; other site
1094466005454	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1094466005455	23S rRNA interface [nucleotide binding]; other site
1094466005456	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1094466005457	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1094466005458	mRNA/rRNA interface [nucleotide binding]; other site
1094466005459	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1094466005460	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1094466005461	23S rRNA interface [nucleotide binding]; other site
1094466005462	L7/L12 interface [polypeptide binding]; other site
1094466005463	putative thiostrepton binding site; other site
1094466005464	L25 interface [polypeptide binding]; other site
1094466005465	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1094466005466	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1094466005467	putative homodimer interface [polypeptide binding]; other site
1094466005468	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1094466005469	heterodimer interface [polypeptide binding]; other site
1094466005470	homodimer interface [polypeptide binding]; other site
1094466005471	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
1094466005472	elongation factor Tu; Reviewed; Region: PRK12735
1094466005473	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1094466005474	G1 box; other site
1094466005475	GEF interaction site [polypeptide binding]; other site
1094466005476	GTP/Mg2+ binding site [chemical binding]; other site
1094466005477	Switch I region; other site
1094466005478	G2 box; other site
1094466005479	G3 box; other site
1094466005480	Switch II region; other site
1094466005481	G4 box; other site
1094466005482	G5 box; other site
1094466005483	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1094466005484	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1094466005485	Antibiotic Binding Site [chemical binding]; other site
1094466005486	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1094466005487	30S subunit binding site; other site
1094466005488	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1094466005489	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1094466005490	active site
1094466005491	DNA binding site [nucleotide binding]
1094466005492	Int/Topo IB signature motif; other site
1094466005493	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1094466005494	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1094466005495	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1094466005496	active site
1094466005497	DNA uptake protein and related DNA-binding proteins [DNA replication, recombination, and repair]; Region: ComEA; COG1555
1094466005498	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1094466005499	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1094466005500	PspC domain; Region: PspC; cl00864
1094466005501	Protein of unknown function (DUF2851); Region: DUF2851; pfam11013
1094466005502	cystathionine beta-synthase; Region: cysta_beta; TIGR01137
1094466005503	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1094466005504	dimer interface [polypeptide binding]; other site
1094466005505	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466005506	catalytic residue [active]
1094466005507	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the pyridoxal-phosphate (PALP) dependent enzyme domain upstream.   The vitamin B6 complex comprises pyridoxine, pyridoxal, and pyridoxamine, as well...; Region: CBS_pair_PALP_assoc2; cd04609
1094466005508	Domain of unknown function (DUF4289); Region: DUF4289; pfam14121
1094466005509	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
1094466005510	starch binding outer membrane protein SusD; Region: SusD; cd08977
1094466005511	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
1094466005512	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466005513	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1094466005514	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466005515	Bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1094466005516	RNA/DNA hybrid binding site [nucleotide binding]; other site
1094466005517	active site
1094466005518	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
1094466005519	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1094466005520	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1094466005521	dimer interface [polypeptide binding]; other site
1094466005522	putative anticodon binding site; other site
1094466005523	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1094466005524	motif 1; other site
1094466005525	active site
1094466005526	motif 2; other site
1094466005527	motif 3; other site
1094466005528	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466005529	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1094466005530	trimer interface [polypeptide binding]; other site
1094466005531	active site
1094466005532	dimer interface [polypeptide binding]; other site
1094466005533	M28 Zn-Peptidases containing a PA domain insert; Region: M28_like_PA; cd03877
1094466005534	Predicted aminopeptidases [General function prediction only]; Region: Iap; COG2234
1094466005535	metal binding site [ion binding]; metal-binding site
1094466005536	Glutamine cyclotransferase; Region: Glu_cyclase_2; cl19848
1094466005537	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
1094466005538	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1094466005539	cysteine synthase; Region: PLN02565
1094466005540	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1094466005541	dimer interface [polypeptide binding]; other site
1094466005542	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466005543	catalytic residue [active]
1094466005544	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; cl01768
1094466005545	di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039
1094466005546	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
1094466005547	AZL_007920/MXAN_0976 family protein; Region: AZL_007920_fam; TIGR04052
1094466005548	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
1094466005549	Domain of unknown function (DUF3784); Region: DUF3784; pfam12650
1094466005550	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482
1094466005551	dimer interface [polypeptide binding]; other site
1094466005552	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1094466005553	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1094466005554	inhibitor-cofactor binding pocket; inhibition site
1094466005555	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466005556	catalytic residue [active]
1094466005557	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
1094466005558	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1094466005559	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1094466005560	1-aminocyclopropane-1-carboxylate deaminase [Amino acid transport and metabolism]; Region: Acd; COG2515
1094466005561	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1094466005562	catalytic residue [active]
1094466005563	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466005564	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466005565	urocanate hydratase; Provisional; Region: PRK05414
1094466005566	Domain of unknown function (DUF4136); Region: DUF4136; pfam13590
1094466005567	Biopterin-dependent aromatic amino acid hydroxylase; a family of non-heme, iron(II)-dependent enzymes that includes prokaryotic and eukaryotic phenylalanine-4-hydroxylase (PheOH), eukaryotic tyrosine hydroxylase (TyrOH) and eukaryotic tryptophan...; Region: arom_aa_hydroxylase; cd00361
1094466005568	cofactor binding site; other site
1094466005569	metal binding site [ion binding]; metal-binding site
1094466005570	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1094466005571	active site residue [active]
1094466005572	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1094466005573	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1094466005574	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466005575	ligand binding site [chemical binding]; other site
1094466005576	Beta-propeller repeat; Region: SBBP; pfam06739
1094466005577	BDLF3; Provisional; Region: PHA03255
1094466005578	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1094466005579	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1094466005580	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466005581	active site
1094466005582	phosphorylation site [posttranslational modification]
1094466005583	intermolecular recognition site; other site
1094466005584	dimerization interface [polypeptide binding]; other site
1094466005585	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1094466005586	DNA binding residues [nucleotide binding]
1094466005587	dimerization interface [polypeptide binding]; other site
1094466005588	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466005589	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466005590	binding surface
1094466005591	TPR motif; other site
1094466005592	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466005593	Histidine kinase; Region: HisKA_3; pfam07730
1094466005594	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466005595	ATP binding site [chemical binding]; other site
1094466005596	Mg2+ binding site [ion binding]; other site
1094466005597	G-X-G motif; other site
1094466005598	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466005599	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466005600	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466005601	binding surface
1094466005602	TPR motif; other site
1094466005603	Histidine kinase; Region: HisKA_3; pfam07730
1094466005604	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466005605	ATP binding site [chemical binding]; other site
1094466005606	Mg2+ binding site [ion binding]; other site
1094466005607	G-X-G motif; other site
1094466005608	Protein of unknown function (DUF4230); Region: DUF4230; pfam14014
1094466005609	FOG: WD40-like repeat [Function unknown]; Region: COG1520
1094466005610	Domain of unknown function (DUF4374); Region: DUF4374; pfam14298
1094466005611	PQQ-like domain; Region: PQQ_2; pfam13360
1094466005612	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
1094466005613	Trp docking motif [polypeptide binding]; other site
1094466005614	active site
1094466005615	Putative bacterial sensory transduction regulator; Region: YbjN; cl15834
1094466005616	GSCFA family; Region: GSCFA; pfam08885
1094466005617	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1094466005618	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1094466005619	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466005620	Walker A/P-loop; other site
1094466005621	ATP binding site [chemical binding]; other site
1094466005622	Q-loop/lid; other site
1094466005623	ABC transporter signature motif; other site
1094466005624	Walker B; other site
1094466005625	D-loop; other site
1094466005626	H-loop/switch region; other site
1094466005627	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1094466005628	homotrimer interaction site [polypeptide binding]; other site
1094466005629	putative active site [active]
1094466005630	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1094466005631	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1094466005632	motif 1; other site
1094466005633	active site
1094466005634	motif 2; other site
1094466005635	motif 3; other site
1094466005636	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1094466005637	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1094466005638	Peptidase family M23; Region: Peptidase_M23; pfam01551
1094466005639	Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators; Region: HTH_MlrA-like_sg2; cd04765
1094466005640	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1094466005641	DNA binding residues [nucleotide binding]
1094466005642	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
1094466005643	TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase; Region: TPM; pfam04536
1094466005644	TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase; Region: TPM; cl01535
1094466005645	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466005646	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1094466005647	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1094466005648	Outer membrane protein beta-barrel family; Region: OMP_b-brl_3; pfam14905
1094466005649	GTP-binding protein Der; Reviewed; Region: PRK00093
1094466005650	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1094466005651	G1 box; other site
1094466005652	GTP/Mg2+ binding site [chemical binding]; other site
1094466005653	Switch I region; other site
1094466005654	G2 box; other site
1094466005655	Switch II region; other site
1094466005656	G3 box; other site
1094466005657	G4 box; other site
1094466005658	G5 box; other site
1094466005659	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1094466005660	G1 box; other site
1094466005661	GTP/Mg2+ binding site [chemical binding]; other site
1094466005662	Switch I region; other site
1094466005663	G2 box; other site
1094466005664	G3 box; other site
1094466005665	Switch II region; other site
1094466005666	G4 box; other site
1094466005667	G5 box; other site
1094466005668	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal; Region: KH_dom-like; pfam14714
1094466005669	GTPase Era; Reviewed; Region: era; PRK00089
1094466005670	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1094466005671	G1 box; other site
1094466005672	GTP/Mg2+ binding site [chemical binding]; other site
1094466005673	Switch I region; other site
1094466005674	G2 box; other site
1094466005675	Switch II region; other site
1094466005676	G3 box; other site
1094466005677	G4 box; other site
1094466005678	G5 box; other site
1094466005679	KH domain; Region: KH_2; pfam07650
1094466005680	two component system sensor kinase SsrB; Provisional; Region: PRK15369
1094466005681	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466005682	active site
1094466005683	phosphorylation site [posttranslational modification]
1094466005684	intermolecular recognition site; other site
1094466005685	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1094466005686	LytTr DNA-binding domain; Region: LytTR; smart00850
1094466005687	Histidine kinase; Region: HisKA_3; pfam07730
1094466005688	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466005689	ATP binding site [chemical binding]; other site
1094466005690	Mg2+ binding site [ion binding]; other site
1094466005691	G-X-G motif; other site
1094466005692	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466005693	binding surface
1094466005694	TPR motif; other site
1094466005695	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466005696	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466005697	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1094466005698	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1094466005699	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1094466005700	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1094466005701	polysaccharide deacetylase family protein, PEP-CTERM locus subfamily; Region: pepcterm_polyde; TIGR03006
1094466005702	Uncharacterized conserved protein [Function unknown]; Region: COG4748
1094466005703	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1094466005704	Formylmethanofuran dehydrogenase subunit A [Energy production and conversion]; Region: FwdA; COG1229
1094466005705	Mycoplasma pulmonis MnuA nuclease-like; Region: MnuA_DNase1-like; cd10283
1094466005706	putative active site [active]
1094466005707	putative catalytic site [active]
1094466005708	putative Mg binding site IVb [ion binding]; other site
1094466005709	putative phosphate binding site [ion binding]; other site
1094466005710	putative DNA binding site [nucleotide binding]; other site
1094466005711	putative Mg binding site IVa [ion binding]; other site
1094466005712	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1094466005713	HSP70 interaction site [polypeptide binding]; other site
1094466005714	KTSC domain; Region: KTSC; pfam13619
1094466005715	Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its homologs; Region: GIY-YIG_SLX1_like; cd10449
1094466005716	GIY-YIG motif/motif A; other site
1094466005717	putative active site [active]
1094466005718	putative metal binding site [ion binding]; other site
1094466005719	Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its homologs; Region: GIY-YIG_SLX1_like; cd10449
1094466005720	GIY-YIG motif/motif A; other site
1094466005721	putative active site [active]
1094466005722	putative metal binding site [ion binding]; other site
1094466005723	chaperonin GroEL; Reviewed; Region: groEL; PRK12850
1094466005724	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1094466005725	ring oligomerisation interface [polypeptide binding]; other site
1094466005726	ATP/Mg binding site [chemical binding]; other site
1094466005727	stacking interactions; other site
1094466005728	hinge regions; other site
1094466005729	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1094466005730	oligomerisation interface [polypeptide binding]; other site
1094466005731	mobile loop; other site
1094466005732	roof hairpin; other site
1094466005733	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1094466005734	Lipopolysaccharide-assembly; Region: LptE; pfam04390
1094466005735	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1094466005736	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1094466005737	Walker A motif; other site
1094466005738	ATP binding site [chemical binding]; other site
1094466005739	Walker B motif; other site
1094466005740	arginine finger; other site
1094466005741	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1094466005742	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14329
1094466005743	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1094466005744	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1094466005745	FeS/SAM binding site; other site
1094466005746	TRAM domain; Region: TRAM; pfam01938
1094466005747	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1094466005748	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1094466005749	active site
1094466005750	interdomain interaction site; other site
1094466005751	putative metal-binding site [ion binding]; other site
1094466005752	nucleotide binding site [chemical binding]; other site
1094466005753	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1094466005754	domain I; other site
1094466005755	DNA binding groove [nucleotide binding]
1094466005756	phosphate binding site [ion binding]; other site
1094466005757	domain II; other site
1094466005758	domain III; other site
1094466005759	nucleotide binding site [chemical binding]; other site
1094466005760	catalytic site [active]
1094466005761	domain IV; other site
1094466005762	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
1094466005763	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
1094466005764	putative active site [active]
1094466005765	putative metal binding site [ion binding]; other site
1094466005766	Sulfatase-modifying factor enzyme 1; Region: FGE-sulfatase; cl19582
1094466005767	gliding motility-associated protein GldL; Region: GldL_gliding; TIGR03513
1094466005768	gliding motility-associated protein GldM; Region: GldM_gliding; TIGR03517
1094466005769	GldM N-terminal domain; Region: GldM_N; pfam12081
1094466005770	GldM C-terminal domain; Region: GldM_C; pfam12080
1094466005771	gliding motility associated protien GldN; Region: GldN; TIGR03523
1094466005772	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1094466005773	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1094466005774	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1094466005775	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1094466005776	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1094466005777	ABC transporter; Region: ABC_tran_2; pfam12848
1094466005778	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1094466005779	DNA replication regulator SLD3; Region: SLD3; pfam08639
1094466005780	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
1094466005781	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
1094466005782	Protein of unknown function (DUF1761); Region: DUF1761; pfam08570
1094466005783	Heavy-metal-associated domain; Region: HMA; pfam00403
1094466005784	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466005785	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
1094466005786	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466005787	Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236
1094466005788	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1094466005789	Beta-Casp domain; Region: Beta-Casp; pfam10996
1094466005790	RNA-metabolizing metallo-beta-lactamase; Region: RMMBL; pfam07521
1094466005791	ATP cone domain; Region: ATP-cone; pfam03477
1094466005792	Restriction endonuclease; Region: Mrr_cat; cl19295
1094466005793	Transmembrane exosortase (Exosortase_EpsH); Region: Exosortase_EpsH; cl15694
1094466005794	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1094466005795	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1094466005796	16S/18S rRNA binding site [nucleotide binding]; other site
1094466005797	S13e-L30e interaction site [polypeptide binding]; other site
1094466005798	25S rRNA binding site [nucleotide binding]; other site
1094466005799	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1094466005800	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1094466005801	RNase E interface [polypeptide binding]; other site
1094466005802	trimer interface [polypeptide binding]; other site
1094466005803	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1094466005804	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1094466005805	RNase E interface [polypeptide binding]; other site
1094466005806	trimer interface [polypeptide binding]; other site
1094466005807	active site
1094466005808	K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; Region: KH-I; cl17245
1094466005809	nucleic acid binding region [nucleotide binding]; other site
1094466005810	G-X-X-G motif; other site
1094466005811	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1094466005812	RNA binding site [nucleotide binding]; other site
1094466005813	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466005814	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1094466005815	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466005816	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1094466005817	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466005818	TPR motif; other site
1094466005819	binding surface
1094466005820	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466005821	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466005822	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1094466005823	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466005824	ATP binding site [chemical binding]; other site
1094466005825	Mg2+ binding site [ion binding]; other site
1094466005826	G-X-G motif; other site
1094466005827	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1094466005828	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466005829	active site
1094466005830	phosphorylation site [posttranslational modification]
1094466005831	intermolecular recognition site; other site
1094466005832	dimerization interface [polypeptide binding]; other site
1094466005833	LytTr DNA-binding domain; Region: LytTR; smart00850
1094466005834	WYL domain; Region: WYL; pfam13280
1094466005835	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
1094466005836	Prokaryotic RING finger family 4; Region: Prok-RING_4; pfam14447
1094466005837	TerD domain; Region: TerD; pfam02342
1094466005838	putative metal binding site [ion binding]; other site
1094466005839	Uncharacterized conserved protein [Function unknown]; Region: RtcB; COG1690
1094466005840	tRNA-splicing ligase RtcB; Region: RtcB; pfam01139
1094466005841	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1094466005842	Domain of unknown function (DUF1842); Region: DUF1842; pfam08896
1094466005843	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1094466005844	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
1094466005845	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1094466005846	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1094466005847	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1094466005848	DNA binding residues [nucleotide binding]
1094466005849	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466005850	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1094466005851	substrate binding site [chemical binding]; other site
1094466005852	hexamer interface [polypeptide binding]; other site
1094466005853	metal binding site [ion binding]; metal-binding site
1094466005854	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1094466005855	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1094466005856	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466005857	Histidine kinase; Region: His_kinase; pfam06580
1094466005858	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1094466005859	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466005860	active site
1094466005861	phosphorylation site [posttranslational modification]
1094466005862	intermolecular recognition site; other site
1094466005863	dimerization interface [polypeptide binding]; other site
1094466005864	LytTr DNA-binding domain; Region: LytTR; smart00850
1094466005865	FOG: CBS domain [General function prediction only]; Region: COG0517
1094466005866	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1094466005867	Glucose-regulated metallo-peptidase M90; Region: Peptidase_M90; cl01267
1094466005868	Yqey-like protein; Region: YqeY; cl17540
1094466005869	cell division protein FtsZ; Validated; Region: PRK09330
1094466005870	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1094466005871	nucleotide binding site [chemical binding]; other site
1094466005872	SulA interaction site; other site
1094466005873	cell division protein FtsA; Region: ftsA; TIGR01174
1094466005874	Cell division protein FtsA; Region: FtsA; smart00842
1094466005875	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1094466005876	nucleotide binding site [chemical binding]; other site
1094466005877	Cell division protein FtsA; Region: FtsA; pfam14450
1094466005878	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1094466005879	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1094466005880	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1094466005881	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1094466005882	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1094466005883	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1094466005884	active site
1094466005885	homodimer interface [polypeptide binding]; other site
1094466005886	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
1094466005887	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
1094466005888	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1094466005889	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1094466005890	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1094466005891	Mg++ binding site [ion binding]; other site
1094466005892	putative catalytic motif [active]
1094466005893	putative substrate binding site [chemical binding]; other site
1094466005894	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1094466005895	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1094466005896	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1094466005897	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1094466005898	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1094466005899	Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717
1094466005900	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1094466005901	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
1094466005902	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1094466005903	cell division protein MraZ; Reviewed; Region: PRK00326
1094466005904	MraZ protein; Region: MraZ; pfam02381
1094466005905	MraZ protein; Region: MraZ; pfam02381
1094466005906	Putative lysophospholipase; Region: Hydrolase_4; cl19140
1094466005907	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1094466005908	Predicted GTPase [General function prediction only]; Region: COG0218
1094466005909	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1094466005910	G1 box; other site
1094466005911	GTP/Mg2+ binding site [chemical binding]; other site
1094466005912	Switch I region; other site
1094466005913	G2 box; other site
1094466005914	G3 box; other site
1094466005915	Switch II region; other site
1094466005916	G4 box; other site
1094466005917	G5 box; other site
1094466005918	phosphoglyceromutase; Provisional; Region: PRK05434
1094466005919	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_2; cd09618
1094466005920	putative ligand binding site [chemical binding]; other site
1094466005921	L,D-transpeptidase catalytic domain; Region: YkuD_2; pfam13645
1094466005922	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2989
1094466005923	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1094466005924	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1094466005925	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1094466005926	YtxH-like protein; Region: YtxH; pfam12732
1094466005927	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
1094466005928	CHASE3 domain; Region: CHASE3; pfam05227
1094466005929	PAS fold; Region: PAS_3; pfam08447
1094466005930	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1094466005931	putative active site [active]
1094466005932	heme pocket [chemical binding]; other site
1094466005933	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1094466005934	dimer interface [polypeptide binding]; other site
1094466005935	phosphorylation site [posttranslational modification]
1094466005936	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466005937	ATP binding site [chemical binding]; other site
1094466005938	Mg2+ binding site [ion binding]; other site
1094466005939	G-X-G motif; other site
1094466005940	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1094466005941	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466005942	active site
1094466005943	phosphorylation site [posttranslational modification]
1094466005944	intermolecular recognition site; other site
1094466005945	dimerization interface [polypeptide binding]; other site
1094466005946	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1094466005947	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1094466005948	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1094466005949	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1094466005950	Coenzyme A binding pocket [chemical binding]; other site
1094466005951	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1094466005952	active site pocket [active]
1094466005953	oxyanion hole [active]
1094466005954	catalytic triad [active]
1094466005955	active site nucleophile [active]
1094466005956	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466005957	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
1094466005958	Zn binding site [ion binding]; other site
1094466005959	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
1094466005960	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1094466005961	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
1094466005962	active site
1094466005963	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1094466005964	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466005965	S-adenosylmethionine binding site [chemical binding]; other site
1094466005966	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
1094466005967	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl18962
1094466005968	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1094466005969	FeS/SAM binding site; other site
1094466005970	PEGA domain; Region: PEGA; pfam08308
1094466005971	Trypsin; Region: Trypsin; pfam00089
1094466005972	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1094466005973	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1094466005974	substrate binding pocket [chemical binding]; other site
1094466005975	chain length determination region; other site
1094466005976	substrate-Mg2+ binding site; other site
1094466005977	catalytic residues [active]
1094466005978	aspartate-rich region 1; other site
1094466005979	active site lid residues [active]
1094466005980	aspartate-rich region 2; other site
1094466005981	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1094466005982	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1094466005983	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1094466005984	DNA binding residues [nucleotide binding]
1094466005985	Protein of unknown function (DUF2680); Region: DUF2680; pfam10925
1094466005986	DNA primase; Validated; Region: dnaG; PRK05667
1094466005987	CHC2 zinc finger; Region: zf-CHC2; cl17510
1094466005988	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1094466005989	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1094466005990	active site
1094466005991	metal binding site [ion binding]; metal-binding site
1094466005992	interdomain interaction site; other site
1094466005993	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1094466005994	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1094466005995	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466005996	active site
1094466005997	phosphorylation site [posttranslational modification]
1094466005998	intermolecular recognition site; other site
1094466005999	dimerization interface [polypeptide binding]; other site
1094466006000	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1094466006001	DNA binding residues [nucleotide binding]
1094466006002	dimerization interface [polypeptide binding]; other site
1094466006003	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1094466006004	homodimer interface [polypeptide binding]; other site
1094466006005	NAD binding pocket [chemical binding]; other site
1094466006006	ATP binding pocket [chemical binding]; other site
1094466006007	Mg binding site [ion binding]; other site
1094466006008	active-site loop [active]
1094466006009	gliding motility-associated lipoprotein GldB; Region: GldB_lipo; TIGR03514
1094466006010	gliding motility-associated protein GldC; Region: GldC; TIGR03515
1094466006011	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
1094466006012	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
1094466006013	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1094466006014	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1094466006015	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1094466006016	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1094466006017	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1094466006018	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1094466006019	Walker A/P-loop; other site
1094466006020	ATP binding site [chemical binding]; other site
1094466006021	Q-loop/lid; other site
1094466006022	ABC transporter signature motif; other site
1094466006023	Walker B; other site
1094466006024	D-loop; other site
1094466006025	H-loop/switch region; other site
1094466006026	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1094466006027	HlyD family secretion protein; Region: HlyD; pfam00529
1094466006028	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
1094466006029	Outer membrane efflux protein; Region: OEP; pfam02321
1094466006030	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1094466006031	Outer membrane efflux protein; Region: OEP; pfam02321
1094466006032	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1094466006033	active site
1094466006034	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466006035	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1094466006036	Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17; Region: ALDH_F4-17_P5CDH; cd07123
1094466006037	Glutamate binding site [chemical binding]; other site
1094466006038	NAD binding site [chemical binding]; other site
1094466006039	catalytic residues [active]
1094466006040	PGAP1-like protein; Region: PGAP1; pfam07819
1094466006041	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466006042	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1094466006043	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466006044	S-adenosylmethionine binding site [chemical binding]; other site
1094466006045	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
1094466006046	putative di-iron ligands [ion binding]; other site
1094466006047	aspartate aminotransferase; Provisional; Region: PRK05764
1094466006048	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1094466006049	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466006050	homodimer interface [polypeptide binding]; other site
1094466006051	catalytic residue [active]
1094466006052	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1094466006053	ATP-grasp domain; Region: ATP-grasp; pfam02222
1094466006054	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1094466006055	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1094466006056	ligand binding site [chemical binding]; other site
1094466006057	flexible hinge region; other site
1094466006058	Ubiquitin-like proteins; Region: UBQ; cl00155
1094466006059	charged pocket; other site
1094466006060	hydrophobic patch; other site
1094466006061	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
1094466006062	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466006063	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466006064	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1094466006065	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1094466006066	DNA binding residues [nucleotide binding]
1094466006067	Pirin; Region: Pirin; pfam02678
1094466006068	Pirin-related protein [General function prediction only]; Region: COG1741
1094466006069	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1094466006070	Coenzyme A binding pocket [chemical binding]; other site
1094466006071	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
1094466006072	Divergent 4Fe-4S mono-cluster; Region: Fer4_19; pfam06902
1094466006073	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1094466006074	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1094466006075	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1094466006076	Peptidase family M23; Region: Peptidase_M23; pfam01551
1094466006077	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
1094466006078	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1094466006079	NAD binding site [chemical binding]; other site
1094466006080	homodimer interface [polypeptide binding]; other site
1094466006081	active site
1094466006082	substrate binding site [chemical binding]; other site
1094466006083	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1094466006084	inhibitor-cofactor binding pocket; inhibition site
1094466006085	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466006086	catalytic residue [active]
1094466006087	3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane]; Region: KdtA; COG1519
1094466006088	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1094466006089	Peptidase S46; Region: Peptidase_S46; pfam10459
1094466006090	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1094466006091	MutS domain I; Region: MutS_I; pfam01624
1094466006092	MutS domain II; Region: MutS_II; pfam05188
1094466006093	MutS domain III; Region: MutS_III; pfam05192
1094466006094	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1094466006095	Walker A/P-loop; other site
1094466006096	ATP binding site [chemical binding]; other site
1094466006097	Q-loop/lid; other site
1094466006098	ABC transporter signature motif; other site
1094466006099	Walker B; other site
1094466006100	D-loop; other site
1094466006101	H-loop/switch region; other site
1094466006102	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1094466006103	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1094466006104	catalytic center binding site [active]
1094466006105	ATP binding site [chemical binding]; other site
1094466006106	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
1094466006107	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
1094466006108	Substrate-binding site [chemical binding]; other site
1094466006109	Substrate specificity [chemical binding]; other site
1094466006110	signal peptide peptidase SppA, 67K type; Region: SppA_67K; TIGR00705
1094466006111	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1094466006112	tandem repeat interface [polypeptide binding]; other site
1094466006113	oligomer interface [polypeptide binding]; other site
1094466006114	active site residues [active]
1094466006115	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1094466006116	tandem repeat interface [polypeptide binding]; other site
1094466006117	oligomer interface [polypeptide binding]; other site
1094466006118	active site residues [active]
1094466006119	AsmA family; Region: AsmA; pfam05170
1094466006120	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1094466006121	Fungalysin metallopeptidase (M36); Region: Peptidase_M36; pfam02128
1094466006122	Peptidase M36 family also known as fungalysin family; Region: M36; cd09596
1094466006123	PA_subtilisin_1: Protease-associated domain containing subtilisin-like proteases, subgroup 1. A subgroup of PA domain-containing subtilisin-like proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined; Region: PA_subtilisin_1; cd04818
1094466006124	PA/protease or protease-like domain interface [polypeptide binding]; other site
1094466006125	Zn binding site [ion binding]; other site
1094466006126	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466006127	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01096
1094466006128	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1094466006129	Zn2+ binding site [ion binding]; other site
1094466006130	Mg2+ binding site [ion binding]; other site
1094466006131	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1094466006132	Coenzyme A binding pocket [chemical binding]; other site
1094466006133	ribonucleoside--diphosphate reductase large subunit; Region: PLN02437
1094466006134	ATP cone domain; Region: ATP-cone; pfam03477
1094466006135	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1094466006136	active site
1094466006137	dimer interface [polypeptide binding]; other site
1094466006138	catalytic residues [active]
1094466006139	effector binding site; other site
1094466006140	R2 peptide binding site; other site
1094466006141	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1094466006142	dimer interface [polypeptide binding]; other site
1094466006143	putative radical transfer pathway; other site
1094466006144	diiron center [ion binding]; other site
1094466006145	tyrosyl radical; other site
1094466006146	Protein of unknown function (DUF3109); Region: DUF3109; pfam11307
1094466006147	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
1094466006148	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1094466006149	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1094466006150	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466006151	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1094466006152	C-terminal peptidase (prc); Region: prc; TIGR00225
1094466006153	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1094466006154	protein binding site [polypeptide binding]; other site
1094466006155	Catalytic dyad [active]
1094466006156	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
1094466006157	catalytic motif [active]
1094466006158	Zn binding site [ion binding]; other site
1094466006159	HupE / UreJ protein; Region: HupE_UreJ_2; pfam13795
1094466006160	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1094466006161	AMP binding site [chemical binding]; other site
1094466006162	metal binding site [ion binding]; metal-binding site
1094466006163	active site
1094466006164	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1094466006165	Coenzyme A binding pocket [chemical binding]; other site
1094466006166	Aspartokinases [Amino acid transport and metabolism]; Region: LysC; COG0527
1094466006167	AAK_AK-HSDH-like: Amino Acid Kinase Superfamily (AAK), AK-HSDH-like; this family includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK- homoserine dehydrogenase (HSDH). These aspartokinases are found in such...; Region: AAK_AK-HSDH-like; cd04243
1094466006168	putative catalytic residues [active]
1094466006169	nucleotide binding site [chemical binding]; other site
1094466006170	aspartate binding site [chemical binding]; other site
1094466006171	High-temperature-induced dauer-formation protein; Region: Hid1; cl15483
1094466006172	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1094466006173	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1094466006174	sequence-specific DNA binding site [nucleotide binding]; other site
1094466006175	salt bridge; other site
1094466006176	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
1094466006177	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1094466006178	putative active site [active]
1094466006179	putative metal binding site [ion binding]; other site
1094466006180	Glycosyl transferase family 1; Region: Glyco_trans_1_3; pfam13528
1094466006181	Cupin-like domain; Region: Cupin_8; pfam13621
1094466006182	biotin synthase; Region: bioB; TIGR00433
1094466006183	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1094466006184	FeS/SAM binding site; other site
1094466006185	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1094466006186	Horizontally Transferred TransMembrane Domain; Region: HTTM; cl02773
1094466006187	Vitamin K-dependent gamma-carboxylase; Region: VKG_Carbox; pfam05090
1094466006188	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1094466006189	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1094466006190	active site
1094466006191	Riboflavin kinase; Region: Flavokinase; smart00904
1094466006192	Zinc-dependent metalloprotease, pappalysin_like subfamily. The pregnancy-associated plasma protein A (PAPP-A or pappalysin-1) cleaves insulin-like growth factor-binding proteins 4 and 5, thereby promoting cell growth by releasing bound growth factor; Region: ZnMc_pappalysin_like; cd04275
1094466006193	active site
1094466006194	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1094466006195	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466006196	Metallo-peptidase family M12B Reprolysin-like; Region: Reprolysin_2; pfam13574
1094466006197	Proprotein convertase P-domain; Region: P_proprotein; pfam01483
1094466006198	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466006199	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1094466006200	putative active site [active]
1094466006201	catalytic residue [active]
1094466006202	SurA N-terminal domain; Region: SurA_N_3; cl07813
1094466006203	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1094466006204	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
1094466006205	Lipopolysaccharide-assembly, LptC-related; Region: LptC; cl01200
1094466006206	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
1094466006207	pantothenate kinase; Reviewed; Region: PRK13320
1094466006208	Bacterial PH domain; Region: bPH_3; pfam14470
1094466006209	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1094466006210	Putative cyclase; Region: Cyclase; pfam04199
1094466006211	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
1094466006212	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1094466006213	FeS/SAM binding site; other site
1094466006214	HemN C-terminal domain; Region: HemN_C; pfam06969
1094466006215	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1094466006216	active site
1094466006217	putative DNA-binding cleft [nucleotide binding]; other site
1094466006218	dimer interface [polypeptide binding]; other site
1094466006219	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
1094466006220	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1094466006221	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1094466006222	active site
1094466006223	Protein of unknown function (DUF456); Region: DUF456; pfam04306
1094466006224	Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its homologs; Region: GIY-YIG_SLX1_like; cd10449
1094466006225	GIY-YIG motif/motif A; other site
1094466006226	putative active site [active]
1094466006227	putative metal binding site [ion binding]; other site
1094466006228	Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its homologs; Region: GIY-YIG_SLX1_like; cd10449
1094466006229	GIY-YIG motif/motif A; other site
1094466006230	putative active site [active]
1094466006231	putative metal binding site [ion binding]; other site
1094466006232	Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its homologs; Region: GIY-YIG_SLX1_like; cd10449
1094466006233	GIY-YIG motif/motif A; other site
1094466006234	putative active site [active]
1094466006235	putative metal binding site [ion binding]; other site
1094466006236	Protein of unknown function DUF58; Region: DUF58; pfam01882
1094466006237	von Willebrand factor (vWF) type A domain; Region: VWA; smart00327
1094466006238	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1094466006239	catalytic residues [active]
1094466006240	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1094466006241	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1094466006242	active site
1094466006243	catalytic site [active]
1094466006244	substrate binding site [chemical binding]; other site
1094466006245	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1094466006246	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1094466006247	active site
1094466006248	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733
1094466006249	Helix-hairpin-helix motif; Region: HHH_6; pfam14579
1094466006250	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1094466006251	generic binding surface I; other site
1094466006252	generic binding surface II; other site
1094466006253	Endonuclease I; Region: Endonuclease_1; cl01003
1094466006254	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1094466006255	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1094466006256	RNA binding surface [nucleotide binding]; other site
1094466006257	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1094466006258	active site
1094466006259	Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Region: PT_UbiA_DGGGPS; cd13961
1094466006260	putative active site [active]
1094466006261	mevalonate kinase; Region: mevalon_kin; TIGR00549
1094466006262	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1094466006263	hypothetical protein; Reviewed; Region: PRK12275
1094466006264	Mevalonate pyrophosphate decarboxylase [Lipid metabolism]; Region: MVD1; COG3407
1094466006265	diphosphomevalonate decarboxylase; Region: PLN02407
1094466006266	TspO/MBR family; Region: TspO_MBR; pfam03073
1094466006267	flavoprotein, HI0933 family; Region: TIGR00275
1094466006268	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1094466006269	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1094466006270	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1094466006271	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1094466006272	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1094466006273	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1094466006274	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1094466006275	Protein of unknown function (Porph_ging); Region: Porph_ging; cl09903
1094466006276	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1094466006277	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
1094466006278	short chain dehydrogenase; Provisional; Region: PRK06914
1094466006279	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1094466006280	NAD(P) binding site [chemical binding]; other site
1094466006281	active site
1094466006282	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
1094466006283	Serine proteases of the peptidase family S9A [Amino acid transport and metabolism]; Region: COG1505
1094466006284	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1094466006285	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466006286	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
1094466006287	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466006288	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1094466006289	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118
1094466006290	Semialdehyde dehydrogenase, dimerization domain; Region: Semialdhyde_dhC; pfam02774
1094466006291	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1094466006292	catalytic residues [active]
1094466006293	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1094466006294	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1094466006295	dimer interface [polypeptide binding]; other site
1094466006296	anticodon binding site; other site
1094466006297	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1094466006298	homodimer interface [polypeptide binding]; other site
1094466006299	motif 1; other site
1094466006300	active site
1094466006301	motif 2; other site
1094466006302	GAD domain; Region: GAD; pfam02938
1094466006303	motif 3; other site
1094466006304	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1094466006305	DNA-binding site [nucleotide binding]; DNA binding site
1094466006306	RNA-binding motif; other site
1094466006307	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535
1094466006308	NADH dehydrogenase subunit B; Provisional; Region: PRK14820
1094466006309	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl19197
1094466006310	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
1094466006311	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1094466006312	Thioredoxin-like [2Fe-2S] ferredoxin; Region: 2Fe-2S_thioredx; pfam01257
1094466006313	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1094466006314	putative dimer interface [polypeptide binding]; other site
1094466006315	[2Fe-2S] cluster binding site [ion binding]; other site
1094466006316	NADH-quinone oxidoreductase, F subunit; Region: nuoF_fam; TIGR01959
1094466006317	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
1094466006318	SLBB domain; Region: SLBB; pfam10531
1094466006319	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1094466006320	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1094466006321	catalytic loop [active]
1094466006322	iron binding site [ion binding]; other site
1094466006323	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1094466006324	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1094466006325	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
1094466006326	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
1094466006327	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1094466006328	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1094466006329	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1094466006330	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1094466006331	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1094466006332	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1094466006333	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1094466006334	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1094466006335	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1094466006336	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
1094466006337	active site
1094466006338	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
1094466006339	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1094466006340	inhibitor-cofactor binding pocket; inhibition site
1094466006341	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466006342	catalytic residue [active]
1094466006343	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
1094466006344	AAA domain; Region: AAA_26; pfam13500
1094466006345	GxxExxY protein; Region: GxxExxY; TIGR04256
1094466006346	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
1094466006347	N-terminal catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_1; cd00649
1094466006348	dimer interface [polypeptide binding]; other site
1094466006349	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
1094466006350	active site
1094466006351	heme binding site [chemical binding]; other site
1094466006352	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
1094466006353	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
1094466006354	8-amino-7-oxononanoate synthase; Region: bioF; TIGR00858
1094466006355	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1094466006356	catalytic residue [active]
1094466006357	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1094466006358	gamma subunit interface [polypeptide binding]; other site
1094466006359	LBP interface [polypeptide binding]; other site
1094466006360	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1094466006361	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1094466006362	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1094466006363	alpha subunit interaction interface [polypeptide binding]; other site
1094466006364	Walker A motif; other site
1094466006365	ATP binding site [chemical binding]; other site
1094466006366	Walker B motif; other site
1094466006367	inhibitor binding site; inhibition site
1094466006368	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1094466006369	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1094466006370	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1094466006371	glutaminase active site [active]
1094466006372	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1094466006373	dimer interface [polypeptide binding]; other site
1094466006374	active site
1094466006375	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1094466006376	dimer interface [polypeptide binding]; other site
1094466006377	active site
1094466006378	Domain of unknown function (DUF4270); Region: DUF4270; pfam14092
1094466006379	Starch synthase catalytic domain; Region: Glyco_transf_5; pfam08323
1094466006380	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1094466006381	active site
1094466006382	ATP-binding site [chemical binding]; other site
1094466006383	pantoate-binding site; other site
1094466006384	HXXH motif; other site
1094466006385	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1094466006386	tetramerization interface [polypeptide binding]; other site
1094466006387	active site
1094466006388	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
1094466006389	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819; cl19187
1094466006390	DNA repair protein RadA; Provisional; Region: PRK11823
1094466006391	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1094466006392	Walker A motif/ATP binding site; other site
1094466006393	ATP binding site [chemical binding]; other site
1094466006394	Walker B motif; other site
1094466006395	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1094466006396	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466006397	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
1094466006398	Transglycosylase; Region: Transgly; pfam00912
1094466006399	N-terminal domain of unknown function (DUF4140); Region: DUF4140; pfam13600
1094466006400	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
1094466006401	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1094466006402	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1094466006403	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
1094466006404	active site
1094466006405	catalytic tetrad [active]
1094466006406	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1094466006407	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466006408	active site
1094466006409	phosphorylation site [posttranslational modification]
1094466006410	intermolecular recognition site; other site
1094466006411	dimerization interface [polypeptide binding]; other site
1094466006412	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1094466006413	DNA binding site [nucleotide binding]
1094466006414	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1094466006415	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1094466006416	dimerization interface [polypeptide binding]; other site
1094466006417	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1094466006418	dimer interface [polypeptide binding]; other site
1094466006419	phosphorylation site [posttranslational modification]
1094466006420	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466006421	ATP binding site [chemical binding]; other site
1094466006422	Mg2+ binding site [ion binding]; other site
1094466006423	G-X-G motif; other site
1094466006424	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1094466006425	Outer membrane efflux protein; Region: OEP; pfam02321
1094466006426	Outer membrane efflux protein; Region: OEP; pfam02321
1094466006427	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1094466006428	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1094466006429	HlyD family secretion protein; Region: HlyD_3; pfam13437
1094466006430	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1094466006431	MMPL family; Region: MMPL; cl14618
1094466006432	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
1094466006433	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466006434	ligand binding site [chemical binding]; other site
1094466006435	Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281
1094466006436	putative active site [active]
1094466006437	putative catalytic site [active]
1094466006438	putative DNA binding site [nucleotide binding]; other site
1094466006439	putative phosphate binding site [ion binding]; other site
1094466006440	metal binding site A [ion binding]; metal-binding site
1094466006441	putative AP binding site [nucleotide binding]; other site
1094466006442	putative metal binding site B [ion binding]; other site
1094466006443	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Region: LPLAT_ACT14924-like; cd07986
1094466006444	putative acyl-acceptor binding pocket; other site
1094466006445	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
1094466006446	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1094466006447	Putative D-isomer specific 2-hydroxyacid dehydrogenases, NAD-binding and catalytic domains; Region: 2-Hacid_dh_14; cd12179
1094466006448	putative ligand binding site [chemical binding]; other site
1094466006449	putative NAD binding site [chemical binding]; other site
1094466006450	catalytic site [active]
1094466006451	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
1094466006452	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1094466006453	FMN binding site [chemical binding]; other site
1094466006454	active site
1094466006455	catalytic residues [active]
1094466006456	substrate binding site [chemical binding]; other site
1094466006457	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1094466006458	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
1094466006459	The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013
1094466006460	Peptidase family M23; Region: Peptidase_M23; pfam01551
1094466006461	Domain of unknown function (DUF4292); Region: DUF4292; pfam14125
1094466006462	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466006463	binding surface
1094466006464	TPR motif; other site
1094466006465	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466006466	binding surface
1094466006467	TPR motif; other site
1094466006468	glucose-1-phosphate thymidylylransferase, long form; Region: rmlA_long; TIGR01208
1094466006469	NTP_transferases catalyze the transfer of nucleotides onto phosphosugars; Region: NTP_transferase; cd04181
1094466006470	active site
1094466006471	Substrate binding site; other site
1094466006472	Mg++ binding site; other site
1094466006473	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1094466006474	putative trimer interface [polypeptide binding]; other site
1094466006475	putative CoA binding site [chemical binding]; other site
1094466006476	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1094466006477	trimer interface [polypeptide binding]; other site
1094466006478	active site
1094466006479	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1094466006480	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1094466006481	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1094466006482	Coenzyme A binding pocket [chemical binding]; other site
1094466006483	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1094466006484	core domain interface [polypeptide binding]; other site
1094466006485	delta subunit interface [polypeptide binding]; other site
1094466006486	epsilon subunit interface [polypeptide binding]; other site
1094466006487	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1094466006488	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1094466006489	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1094466006490	beta subunit interaction interface [polypeptide binding]; other site
1094466006491	Walker A motif; other site
1094466006492	ATP binding site [chemical binding]; other site
1094466006493	Walker B motif; other site
1094466006494	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1094466006495	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1094466006496	F0F1 ATP synthase subunit B; Provisional; Region: PRK14471
1094466006497	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1094466006498	ATP synthase subunit C; Region: ATP-synt_C; cl00466
1094466006499	ATP synthase A chain; Region: ATP-synt_A; cl00413
1094466006500	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
1094466006501	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1094466006502	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
1094466006503	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466006504	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1729
1094466006505	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1094466006506	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1094466006507	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1094466006508	ATP binding site [chemical binding]; other site
1094466006509	putative Mg++ binding site [ion binding]; other site
1094466006510	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1094466006511	nucleotide binding region [chemical binding]; other site
1094466006512	ATP-binding site [chemical binding]; other site
1094466006513	TRCF domain; Region: TRCF; pfam03461
1094466006514	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1094466006515	L-threonine dehydrogenase, extended (e) SDRs; Region: TDH_SDR_e; cd05272
1094466006516	NAD binding site [chemical binding]; other site
1094466006517	homodimer interface [polypeptide binding]; other site
1094466006518	active site
1094466006519	putative substrate binding site [chemical binding]; other site
1094466006520	SnoaL-like domain; Region: SnoaL_3; pfam13474
1094466006521	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1094466006522	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1094466006523	mRNA stabilisation; Region: mRNA_stabil; pfam13929
1094466006524	FtsX-like permease family; Region: FtsX; pfam02687
1094466006525	Ribosome-binding factor A; Region: RBFA; pfam02033
1094466006526	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
1094466006527	dimer interface [polypeptide binding]; other site
1094466006528	substrate binding site [chemical binding]; other site
1094466006529	metal binding site [ion binding]; metal-binding site
1094466006530	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
1094466006531	Lumazine binding domain; Region: Lum_binding; pfam00677
1094466006532	Lumazine binding domain; Region: Lum_binding; pfam00677
1094466006533	4-hydroxythreonine-4-phosphate dehydrogenase; Region: pdxA; TIGR00557
1094466006534	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
1094466006535	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1094466006536	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1094466006537	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1094466006538	dimer interface [polypeptide binding]; other site
1094466006539	active site
1094466006540	CoA binding pocket [chemical binding]; other site
1094466006541	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1094466006542	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1094466006543	carboxyltransferase (CT) interaction site; other site
1094466006544	biotinylation site [posttranslational modification]; other site
1094466006545	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1094466006546	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1094466006547	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1094466006548	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1094466006549	ACT domain; Region: ACT_7; pfam13840
1094466006550	Uncharacterized protein family UPF0102; Region: UPF0102; cl00516
1094466006551	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1094466006552	dimer interface [polypeptide binding]; other site
1094466006553	catalytic triad [active]
1094466006554	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1094466006555	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1094466006556	active site
1094466006557	HIGH motif; other site
1094466006558	YhfH-like protein; Region: YhfH; pfam14149
1094466006559	KMSKS motif; other site
1094466006560	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1094466006561	tRNA binding surface [nucleotide binding]; other site
1094466006562	anticodon binding site; other site
1094466006563	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1094466006564	dimer interface [polypeptide binding]; other site
1094466006565	putative tRNA-binding site [nucleotide binding]; other site
1094466006566	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
1094466006567	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1094466006568	motif II; other site
1094466006569	Chloramphenicol acetyltransferase; Region: CAT; smart01059
1094466006570	Histone deacetylase class IV also known as histone deacetylase 11; Region: HDAC_classIV; cd09993
1094466006571	putative active site [active]
1094466006572	Zn binding site [ion binding]; other site
1094466006573	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1094466006574	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1094466006575	dimer interface [polypeptide binding]; other site
1094466006576	ssDNA binding site [nucleotide binding]; other site
1094466006577	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1094466006578	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1094466006579	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1094466006580	dimer interface [polypeptide binding]; other site
1094466006581	ssDNA binding site [nucleotide binding]; other site
1094466006582	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1094466006583	TopoisomeraseII; Region: TOP2c; smart00433
1094466006584	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1094466006585	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1094466006586	putative NAD(P) binding site [chemical binding]; other site
1094466006587	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466006588	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1094466006589	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466006590	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
1094466006591	putative catalytic site [active]
1094466006592	putative metal binding site [ion binding]; other site
1094466006593	putative phosphate binding site [ion binding]; other site
1094466006594	3-hydroxyanthranilate 3,4-dioxygenase; Provisional; Region: PRK13264
1094466006595	NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B; Region: ALDH_F7_AASADH; cd07130
1094466006596	tetrameric interface [polypeptide binding]; other site
1094466006597	NAD binding site [chemical binding]; other site
1094466006598	catalytic residues [active]
1094466006599	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; smart00782
1094466006600	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
1094466006601	PhnA protein; Region: PhnA; pfam03831
1094466006602	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
1094466006603	putative protein phosphatase; Region: PHA02239
1094466006604	active site
1094466006605	metal binding site [ion binding]; metal-binding site
1094466006606	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
1094466006607	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1094466006608	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1094466006609	G1 box; other site
1094466006610	GTP/Mg2+ binding site [chemical binding]; other site
1094466006611	Switch I region; other site
1094466006612	G2 box; other site
1094466006613	G3 box; other site
1094466006614	Switch II region; other site
1094466006615	G4 box; other site
1094466006616	G5 box; other site
1094466006617	Nucleoside recognition; Region: Gate; pfam07670
1094466006618	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1094466006619	Nucleoside recognition; Region: Gate; pfam07670
1094466006620	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
1094466006621	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466006622	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
1094466006623	Mn-dependent transcriptional regulator [Transcription]; Region: TroR; COG1321
1094466006624	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1094466006625	Iron dependent repressor, metal binding and dimerization domain; Region: Fe_dep_repr_C; pfam02742
1094466006626	FeoA domain; Region: FeoA; pfam04023
1094466006627	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
1094466006628	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466006629	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1094466006630	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
1094466006631	HlyD family secretion protein; Region: HlyD_3; pfam13437
1094466006632	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1094466006633	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1094466006634	Outer membrane efflux protein; Region: OEP; pfam02321
1094466006635	Outer membrane efflux protein; Region: OEP; pfam02321
1094466006636	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
1094466006637	Protein of unknown function (Porph_ging); Region: Porph_ging; cl09903
1094466006638	Disulphide isomerase; Region: Disulph_isomer; pfam06491
1094466006639	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1094466006640	putative acyl-acceptor binding pocket; other site
1094466006641	Acyl ACP desaturase, ferritin-like diiron-binding domain; Region: Acyl_ACP_Desat; cd01050
1094466006642	homodimer interface [polypeptide binding]; other site
1094466006643	putative substrate binding pocket [chemical binding]; other site
1094466006644	diiron center [ion binding]; other site
1094466006645	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1094466006646	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1094466006647	Zn2+ binding site [ion binding]; other site
1094466006648	Mg2+ binding site [ion binding]; other site
1094466006649	glutamate dehydrogenase; Provisional; Region: PRK09414
1094466006650	Glu/Leu/Phe/Val dehydrogenase, dimerization domain; Region: ELFV_dehydrog_N; pfam02812
1094466006651	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1094466006652	NAD(P) binding site [chemical binding]; other site
1094466006653	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466006654	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466006655	Acyl-protein synthetase, LuxE; Region: LuxE; pfam04443
1094466006656	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1094466006657	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1094466006658	active site
1094466006659	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
1094466006660	putative acyl-acceptor binding pocket; other site
1094466006661	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1094466006662	cytoplasmic asparaginase I; Provisional; Region: ansA; PRK09461
1094466006663	active site
1094466006664	homodimer interface [polypeptide binding]; other site
1094466006665	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
1094466006666	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1094466006667	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1094466006668	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1094466006669	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1094466006670	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1094466006671	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1094466006672	putative dimer interface [polypeptide binding]; other site
1094466006673	putative anticodon binding site; other site
1094466006674	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1094466006675	homodimer interface [polypeptide binding]; other site
1094466006676	motif 1; other site
1094466006677	motif 2; other site
1094466006678	active site
1094466006679	motif 3; other site
1094466006680	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1094466006681	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1094466006682	NAD(P) binding site [chemical binding]; other site
1094466006683	active site
1094466006684	Domain of unknown function (DUF4296); Region: DUF4296; pfam14129
1094466006685	dihydroorotase; Reviewed; Region: PRK09236
1094466006686	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1094466006687	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
1094466006688	active site
1094466006689	D-aminoacylase, C-terminal region; Region: D-aminoacyl_C; pfam07908
1094466006690	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1094466006691	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
1094466006692	Ligand binding site; other site
1094466006693	Putative Catalytic site; other site
1094466006694	DXD motif; other site
1094466006695	Domain of unknown function (DUF4271); Region: DUF4271; pfam14093
1094466006696	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1094466006697	active site
1094466006698	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1094466006699	active site
1094466006700	substrate-binding site [chemical binding]; other site
1094466006701	metal-binding site [ion binding]
1094466006702	ATP binding site [chemical binding]; other site
1094466006703	Uncharacterized small membrane protein [Function unknown]; Region: COG2363
1094466006704	Saccharopine dehydrogenase; Region: Saccharop_dh; pfam03435
1094466006705	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1094466006706	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1094466006707	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1094466006708	putative DNA binding site [nucleotide binding]; other site
1094466006709	putative Zn2+ binding site [ion binding]; other site
1094466006710	AsnC family; Region: AsnC_trans_reg; pfam01037
1094466006711	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
1094466006712	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1094466006713	catalytic residues [active]
1094466006714	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1094466006715	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1094466006716	active site
1094466006717	HIGH motif; other site
1094466006718	nucleotide binding site [chemical binding]; other site
1094466006719	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1094466006720	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1094466006721	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1094466006722	active site
1094466006723	active site
1094466006724	KMSKS motif; other site
1094466006725	KMSKS motif; other site
1094466006726	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1094466006727	tRNA binding surface [nucleotide binding]; other site
1094466006728	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
1094466006729	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
1094466006730	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1094466006731	Protein of unknown function (DUF3098); Region: DUF3098; pfam11297
1094466006732	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
1094466006733	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
1094466006734	trimer interface [polypeptide binding]; other site
1094466006735	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
1094466006736	trimer interface [polypeptide binding]; other site
1094466006737	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
1094466006738	Prefoldin subunit; Region: Prefoldin_2; pfam01920
1094466006739	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1094466006740	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466006741	active site
1094466006742	phosphorylation site [posttranslational modification]
1094466006743	intermolecular recognition site; other site
1094466006744	dimerization interface [polypeptide binding]; other site
1094466006745	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1094466006746	DNA binding residues [nucleotide binding]
1094466006747	dimerization interface [polypeptide binding]; other site
1094466006748	Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some...; Region: chitinase_glyco_hydro_19; cd00325
1094466006749	putative sugar binding site [chemical binding]; other site
1094466006750	catalytic residues [active]
1094466006751	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466006752	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1094466006753	catalytic residues [active]
1094466006754	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; cl09821
1094466006755	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; cl09821
1094466006756	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; cl09821
1094466006757	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1094466006758	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1094466006759	binding surface
1094466006760	TPR motif; other site
1094466006761	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1094466006762	Histidine kinase; Region: HisKA_3; pfam07730
1094466006763	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466006764	ATP binding site [chemical binding]; other site
1094466006765	Mg2+ binding site [ion binding]; other site
1094466006766	G-X-G motif; other site
1094466006767	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1094466006768	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1094466006769	active site
1094466006770	phosphorylation site [posttranslational modification]
1094466006771	intermolecular recognition site; other site
1094466006772	dimerization interface [polypeptide binding]; other site
1094466006773	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1094466006774	DNA binding residues [nucleotide binding]
1094466006775	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
1094466006776	Histidine kinase; Region: HisKA_3; pfam07730
1094466006777	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1094466006778	ATP binding site [chemical binding]; other site
1094466006779	Mg2+ binding site [ion binding]; other site
1094466006780	G-X-G motif; other site
1094466006781	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1094466006782	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1094466006783	RNA binding site [nucleotide binding]; other site
1094466006784	active site
1094466006785	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; pfam05708
1094466006786	Thioredoxin; Region: Thioredoxin_9; pfam14595
1094466006787	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1094466006788	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
1094466006789	active site
1094466006790	nucleophile elbow; other site
1094466006791	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1094466006792	putative nucleotide binding site [chemical binding]; other site
1094466006793	uridine monophosphate binding site [chemical binding]; other site
1094466006794	homohexameric interface [polypeptide binding]; other site
1094466006795	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1094466006796	hinge region; other site
1094466006797	Metallo-peptidase family M12B Reprolysin-like; Region: Reprolysin_2; pfam13574
1094466006798	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1094466006799	RecX family; Region: RecX; pfam02631
1094466006800	thiamine monophosphate kinase; Provisional; Region: PRK05731
1094466006801	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1094466006802	ATP binding site [chemical binding]; other site
1094466006803	dimerization interface [polypeptide binding]; other site
1094466006804	glycyl-tRNA synthetase; Provisional; Region: PRK04173
1094466006805	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
1094466006806	dimer interface [polypeptide binding]; other site
1094466006807	motif 1; other site
1094466006808	active site
1094466006809	motif 2; other site
1094466006810	motif 3; other site
1094466006811	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
1094466006812	anticodon binding site; other site
1094466006813	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1094466006814	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1094466006815	active site
1094466006816	Bacterial Ig-like domain; Region: Big_5; pfam13205
1094466006817	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1094466006818	putative active site [active]
1094466006819	catalytic triad [active]
1094466006820	dimer interface [polypeptide binding]; other site
1094466006821	multimer interface [polypeptide binding]; other site
1094466006822	succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Validated; Region: PRK07570
1094466006823	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1094466006824	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
1094466006825	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK07573
1094466006826	L-aspartate oxidase; Provisional; Region: PRK06175
1094466006827	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1094466006828	succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; Region: sdhC_b558_fam; TIGR02046
1094466006829	Succinate:quinone oxidoreductase (SQR)-like Type B subfamily 2, transmembrane subunit; composed of proteins with similarity to the SQRs of Geobacter metallireducens and Corynebacterium glutamicum. SQR catalyzes the oxidation of succinate to fumarate...; Region: SQR_TypeB_2_TM; cd03498
1094466006830	putative Iron-sulfur protein interface [polypeptide binding]; other site
1094466006831	proximal heme binding site [chemical binding]; other site
1094466006832	distal heme binding site [chemical binding]; other site
1094466006833	putative dimer interface [polypeptide binding]; other site
1094466006834	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
1094466006835	Asp-box motif; other site
1094466006836	Protein of unknown function, DUF399; Region: DUF399; cl01139
1094466006837	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1094466006838	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1094466006839	ligand binding site [chemical binding]; other site
1094466006840	flexible hinge region; other site
1094466006841	proline aminopeptidase P II; Provisional; Region: PRK10879
1094466006842	Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011
1094466006843	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1094466006844	active site
1094466006845	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1094466006846	Putative lysophospholipase; Region: Hydrolase_4; cl19140
1094466006847	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; cl19402
1094466006848	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1094466006849	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1094466006850	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1094466006851	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1094466006852	ligand binding site [chemical binding]; other site
1094466006853	8-amino-7-oxononanoate synthase; Region: bioF; TIGR00858
1094466006854	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1094466006855	substrate-cofactor binding pocket; other site
1094466006856	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466006857	catalytic residue [active]
1094466006858	Part of AAA domain; Region: AAA_19; pfam13245
1094466006859	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) [DNA replication, recombination, and repair]; Region: RecB; COG1074
1094466006860	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
1094466006861	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1094466006862	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1094466006863	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1094466006864	Predicted exporters of the RND superfamily [General function prediction only]; Region: COG1033
1094466006865	MMPL family; Region: MMPL; cl14618
1094466006866	MMPL family; Region: MMPL; cl14618
1094466006867	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1094466006868	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1094466006869	active site
1094466006870	HIGH motif; other site
1094466006871	dimer interface [polypeptide binding]; other site
1094466006872	KMSKS motif; other site
1094466006873	Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism]; Region: PurF; COG0034
1094466006874	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
1094466006875	active site
1094466006876	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1094466006877	active site
1094466006878	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1094466006879	substrate binding site [chemical binding]; other site
1094466006880	ATP binding site [chemical binding]; other site
1094466006881	Protein of unknown function (DUF983); Region: DUF983; cl02211
1094466006882	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1094466006883	Helix-turn-helix domain; Region: HTH_18; pfam12833
1094466006884	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1094466006885	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1094466006886	RNA/DNA hybrid binding site [nucleotide binding]; other site
1094466006887	active site
1094466006888	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1094466006889	active site
1094466006890	substrate binding site [chemical binding]; other site
1094466006891	cosubstrate binding site; other site
1094466006892	catalytic site [active]
1094466006893	acyl carrier protein; Provisional; Region: acpP; PRK00982
1094466006894	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1094466006895	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1094466006896	dimer interface [polypeptide binding]; other site
1094466006897	active site
1094466006898	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
1094466006899	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1094466006900	dimerization interface [polypeptide binding]; other site
1094466006901	active site
1094466006902	metal binding site [ion binding]; metal-binding site
1094466006903	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1094466006904	dsRNA binding site [nucleotide binding]; other site
1094466006905	Pyruvate kinase [Carbohydrate transport and metabolism]; Region: PykF; COG0469
1094466006906	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1094466006907	domain interfaces; other site
1094466006908	active site
1094466006909	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1094466006910	Outer membrane protein beta-barrel family; Region: OMP_b-brl_3; pfam14905
1094466006911	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1094466006912	GTP-binding protein LepA; Provisional; Region: PRK05433
1094466006913	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1094466006914	G1 box; other site
1094466006915	putative GEF interaction site [polypeptide binding]; other site
1094466006916	GTP/Mg2+ binding site [chemical binding]; other site
1094466006917	Switch I region; other site
1094466006918	G2 box; other site
1094466006919	G3 box; other site
1094466006920	Switch II region; other site
1094466006921	G4 box; other site
1094466006922	G5 box; other site
1094466006923	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1094466006924	Elongation Factor G, domain II; Region: EFG_II; pfam14492
1094466006925	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1094466006926	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1094466006927	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
1094466006928	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1094466006929	active site
1094466006930	DNA polymerase IV; Validated; Region: PRK02406
1094466006931	DNA binding site [nucleotide binding]
1094466006932	CYTH-like Clostridium thermocellum TTM-like subgroup 1; Region: CYTH-like_CthTTM-like_1; cd07891
1094466006933	putative active site [active]
1094466006934	putative metal binding residues [ion binding]; other site
1094466006935	signature motif; other site
1094466006936	putative dimer interface [polypeptide binding]; other site
1094466006937	putative phosphate binding site [ion binding]; other site
1094466006938	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1094466006939	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; cl00360
1094466006940	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
1094466006941	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1094466006942	catalytic residue [active]
1094466006943	Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like; uncharacterized subgroup; Region: M14_ASTE_ASPA_like_1; cd06251
1094466006944	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
1094466006945	putative active site [active]
1094466006946	Zn binding site [ion binding]; other site
1094466006947	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1094466006948	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1094466006949	GIY-YIG motif/motif A; other site
1094466006950	active site
1094466006951	catalytic site [active]
1094466006952	putative DNA binding site [nucleotide binding]; other site
1094466006953	metal binding site [ion binding]; metal-binding site
1094466006954	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1094466006955	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
1094466006956	DNA binding site [nucleotide binding]
1094466006957	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1094466006958	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
1094466006959	active site
1094466006960	nucleophile elbow; other site
1094466006961	Surface antigen; Region: Bac_surface_Ag; pfam01103
1094466006962	amino acid transporter; Region: 2A0306; TIGR00909
1094466006963	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
1094466006964	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1094466006965	homogentisate 1,2-dioxygenase; Region: HgmA; cl17306
1094466006966	4-hydroxyphenylpyruvate dioxygenase; Region: 4HPPD; TIGR01263
1094466006967	N-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS); Region: HPPD_N_like; cd08342
1094466006968	dimer interface [polypeptide binding]; other site
1094466006969	C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS); Region: HPPD_C_like; cd07250
1094466006970	active site
1094466006971	Fe binding site [ion binding]; other site
1094466006972	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
1094466006973	Tryptophan 2,3-dioxygenase; Region: Trp_dioxygenase; cl03994
1094466006974	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1094466006975	Peptidase family M23; Region: Peptidase_M23; pfam01551
1094466006976	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1094466006977	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1094466006978	active site
1094466006979	dimer interface [polypeptide binding]; other site
1094466006980	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1094466006981	dimer interface [polypeptide binding]; other site
1094466006982	active site
1094466006983	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466006984	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1094466006985	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1094466006986	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
1094466006987	Uncharacterized membrane protein [Function unknown]; Region: SpmB; cl17667
1094466006988	RNA polymerase beta'' subunit; Reviewed; Region: rpoC2; CHL00117
1094466006989	fumarate hydratase; Provisional; Region: PRK15389
1094466006990	Fumarate hydratase (Fumerase); Region: Fumerase; pfam05681
1094466006991	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1094466006992	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1094466006993	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
1094466006994	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1094466006995	putative RNA binding site [nucleotide binding]; other site
1094466006996	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1094466006997	S-adenosylmethionine binding site [chemical binding]; other site
1094466006998	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1094466006999	23S rRNA-intervening sequence protein; Region: 23S_rRNA_IVP; cl05287
1094466007000	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
1094466007001	Transglycosylase; Region: Transgly; pfam00912
1094466007002	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1094466007003	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1094466007004	GldH lipoprotein; Region: GldH_lipo; pfam14109
1094466007005	PSP1 C-terminal conserved region; Region: PSP1; cl00770
1094466007006	4Fe-4S single cluster domain; Region: Fer4_13; pfam13370
1094466007007	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
1094466007008	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1094466007009	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1094466007010	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1094466007011	active site residue [active]
1094466007012	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
1094466007013	recombinase A; Provisional; Region: recA; PRK09354
1094466007014	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1094466007015	hexamer interface [polypeptide binding]; other site
1094466007016	Walker A motif; other site
1094466007017	ATP binding site [chemical binding]; other site
1094466007018	Walker B motif; other site
1094466007019	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1094466007020	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1094466007021	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1094466007022	DNA binding residues [nucleotide binding]
1094466007023	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1094466007024	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1094466007025	putative acyl-acceptor binding pocket; other site
1094466007026	tryptophanyl-tRNA synthetase; Reviewed; Region: PRK00927
1094466007027	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1094466007028	active site
1094466007029	HIGH motif; other site
1094466007030	dimer interface [polypeptide binding]; other site
1094466007031	KMSKS motif; other site
1094466007032	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
1094466007033	Helix-hairpin-helix domain; Region: HHH_5; pfam14520
1094466007034	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
1094466007035	Sporulation related domain; Region: SPOR; pfam05036
1094466007036	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1094466007037	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
1094466007038	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
1094466007039	FAD binding pocket [chemical binding]; other site
1094466007040	FAD binding motif [chemical binding]; other site
1094466007041	phosphate binding motif [ion binding]; other site
1094466007042	beta-alpha-beta structure motif; other site
1094466007043	NAD(p) ribose binding residues [chemical binding]; other site
1094466007044	NAD binding pocket [chemical binding]; other site
1094466007045	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
1094466007046	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1094466007047	catalytic loop [active]
1094466007048	iron binding site [ion binding]; other site
1094466007049	Helix-turn-helix domain; Region: HTH_18; pfam12833
1094466007050	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1094466007051	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1094466007052	putative active site [active]
1094466007053	Protein of unknown function (DUF4254); Region: DUF4254; pfam14063
1094466007054	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1094466007055	active site
1094466007056	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1094466007057	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1094466007058	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1094466007059	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1094466007060	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
1094466007061	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1094466007062	AMP binding site [chemical binding]; other site
1094466007063	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1094466007064	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1094466007065	active site
1094466007066	Undecaprenyl-phosphate glucose phosphotransferase; Region: WcaJ_sugtrans; TIGR03023
1094466007067	CoA binding domain; Region: CoA_binding; cl17356
1094466007068	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1094466007069	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1094466007070	UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230
1094466007071	NAD binding site [chemical binding]; other site
1094466007072	putative substrate binding site 2 [chemical binding]; other site
1094466007073	putative substrate binding site 1 [chemical binding]; other site
1094466007074	active site
1094466007075	O-Antigen ligase; Region: Wzy_C; pfam04932
1094466007076	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1094466007077	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_6; cd04955
1094466007078	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
1094466007079	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1094466007080	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1094466007081	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1094466007082	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl19158
1094466007083	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1094466007084	inhibitor-cofactor binding pocket; inhibition site
1094466007085	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1094466007086	catalytic residue [active]
1094466007087	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
1094466007088	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1094466007089	NADP binding site [chemical binding]; other site
1094466007090	active site
1094466007091	putative substrate binding site [chemical binding]; other site
1094466007092	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
1094466007093	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1094466007094	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1094466007095	substrate binding site; other site
1094466007096	tetramer interface; other site
1094466007097	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1094466007098	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
1094466007099	NAD binding site [chemical binding]; other site
1094466007100	substrate binding site [chemical binding]; other site
1094466007101	homodimer interface [polypeptide binding]; other site
1094466007102	active site
1094466007103	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1094466007104	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
1094466007105	GH3 auxin-responsive promoter; Region: GH3; pfam03321
1094466007106	indole-3-acetic acid-amido synthetase; Region: PLN02249
1094466007107	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
1094466007108	Peptidase family M23; Region: Peptidase_M23; pfam01551
1094466007109	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
1094466007110	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1094466007111	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1094466007112	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1094466007113	Uncharacterized protein family (UPF0081); Region: UPF0081; cl17278
1094466007114	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1094466007115	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1094466007116	RNA binding site [nucleotide binding]; other site
1094466007117	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1094466007118	putative substrate binding site [chemical binding]; other site
1094466007119	putative ATP binding site [chemical binding]; other site
1094466007120	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
1094466007121	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
1094466007122	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4430
1094466007123	FG-GAP repeat; Region: FG-GAP_2; pfam14312
1094466007124	FG-GAP repeat; Region: FG-GAP_2; pfam14312
1094466007125	FG-GAP repeat; Region: FG-GAP_2; pfam14312
1094466007126	FG-GAP repeat; Region: FG-GAP_2; pfam14312
1094466007127	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183