-- dump date   	20140619_083206
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1335916000001	putative RNA methyltransferase; Provisional; Region: PRK10433
1335916000002	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050
1335916000003	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1335916000004	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1335916000005	putative catalytic residues [active]
1335916000006	putative nucleotide binding site [chemical binding]; other site
1335916000007	putative aspartate binding site [chemical binding]; other site
1335916000008	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1335916000009	dimer interface [polypeptide binding]; other site
1335916000010	putative threonine allosteric regulatory site; other site
1335916000011	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1335916000012	putative threonine allosteric regulatory site; other site
1335916000013	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1335916000014	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1335916000015	homoserine kinase; Region: thrB; TIGR00191
1335916000016	Protein of unknown function; Region: YhfT; pfam10797
1335916000017	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1335916000018	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1335916000019	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1335916000020	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916000021	catalytic residue [active]
1335916000022	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1335916000023	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1335916000024	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1335916000025	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1335916000026	hypothetical protein; Validated; Region: PRK02101
1335916000027	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1335916000028	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1335916000029	transaldolase-like protein; Provisional; Region: PTZ00411
1335916000030	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1335916000031	active site
1335916000032	dimer interface [polypeptide binding]; other site
1335916000033	catalytic residue [active]
1335916000034	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1335916000035	MPT binding site; other site
1335916000036	trimer interface [polypeptide binding]; other site
1335916000037	hypothetical protein; Provisional; Region: PRK10659
1335916000038	hypothetical protein; Provisional; Region: PRK10236
1335916000039	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
1335916000040	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
1335916000041	hypothetical protein; Provisional; Region: PRK10154
1335916000042	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1335916000043	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
1335916000044	nucleotide binding site [chemical binding]; other site
1335916000045	NEF interaction site [polypeptide binding]; other site
1335916000046	SBD interface [polypeptide binding]; other site
1335916000047	chaperone protein DnaJ; Provisional; Region: PRK10767
1335916000048	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1335916000049	HSP70 interaction site [polypeptide binding]; other site
1335916000050	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1335916000051	substrate binding site [polypeptide binding]; other site
1335916000052	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1335916000053	Zn binding sites [ion binding]; other site
1335916000054	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1335916000055	dimer interface [polypeptide binding]; other site
1335916000056	Hok/gef family; Region: HOK_GEF; pfam01848
1335916000057	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1335916000058	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
1335916000059	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916000060	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
1335916000061	putative dimerization interface [polypeptide binding]; other site
1335916000062	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1335916000063	PapC C-terminal domain; Region: PapC_C; pfam13953
1335916000064	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1335916000065	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1335916000066	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
1335916000067	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1335916000068	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1335916000069	active site
1335916000070	Riboflavin kinase; Region: Flavokinase; smart00904
1335916000071	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1335916000072	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1335916000073	HIGH motif; other site
1335916000074	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1335916000075	active site
1335916000076	KMSKS motif; other site
1335916000077	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1335916000078	tRNA binding surface [nucleotide binding]; other site
1335916000079	anticodon binding site; other site
1335916000080	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1335916000081	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1335916000082	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1335916000083	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1335916000084	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1335916000085	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1335916000086	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1335916000087	active site
1335916000088	tetramer interface [polypeptide binding]; other site
1335916000089	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1335916000090	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1335916000091	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1335916000092	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1335916000093	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1335916000094	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1335916000095	catalytic site [active]
1335916000096	subunit interface [polypeptide binding]; other site
1335916000097	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1335916000098	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1335916000099	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1335916000100	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1335916000101	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1335916000102	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1335916000103	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1335916000104	IMP binding site; other site
1335916000105	dimer interface [polypeptide binding]; other site
1335916000106	interdomain contacts; other site
1335916000107	partial ornithine binding site; other site
1335916000108	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
1335916000109	carnitine operon protein CaiE; Provisional; Region: PRK13627
1335916000110	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
1335916000111	putative trimer interface [polypeptide binding]; other site
1335916000112	putative metal binding site [ion binding]; other site
1335916000113	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
1335916000114	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1335916000115	substrate binding site [chemical binding]; other site
1335916000116	oxyanion hole (OAH) forming residues; other site
1335916000117	trimer interface [polypeptide binding]; other site
1335916000118	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
1335916000119	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
1335916000120	acyl-activating enzyme (AAE) consensus motif; other site
1335916000121	putative AMP binding site [chemical binding]; other site
1335916000122	putative active site [active]
1335916000123	putative CoA binding site [chemical binding]; other site
1335916000124	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
1335916000125	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1335916000126	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
1335916000127	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1335916000128	active site
1335916000129	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
1335916000130	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1335916000131	Ligand binding site [chemical binding]; other site
1335916000132	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1335916000133	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
1335916000134	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF; cd01985
1335916000135	Ligand binding site [chemical binding]; other site
1335916000136	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1335916000137	putative oxidoreductase FixC; Provisional; Region: PRK10157
1335916000138	ferredoxin-like protein FixX; Provisional; Region: PRK15449
1335916000139	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916000140	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1335916000141	putative substrate translocation pore; other site
1335916000142	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
1335916000143	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
1335916000144	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1335916000145	TrkA-N domain; Region: TrkA_N; pfam02254
1335916000146	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1335916000147	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1335916000148	folate binding site [chemical binding]; other site
1335916000149	NADP+ binding site [chemical binding]; other site
1335916000150	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
1335916000151	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1335916000152	active site
1335916000153	metal binding site [ion binding]; metal-binding site
1335916000154	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1335916000155	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1335916000156	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1335916000157	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1335916000158	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1335916000159	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1335916000160	SurA N-terminal domain; Region: SurA_N; pfam09312
1335916000161	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1335916000162	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1335916000163	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1335916000164	OstA-like protein; Region: OstA; pfam03968
1335916000165	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1335916000166	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1335916000167	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1335916000168	putative metal binding site [ion binding]; other site
1335916000169	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1335916000170	HSP70 interaction site [polypeptide binding]; other site
1335916000171	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1335916000172	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1335916000173	active site
1335916000174	ATP-dependent helicase HepA; Validated; Region: PRK04914
1335916000175	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1335916000176	ATP binding site [chemical binding]; other site
1335916000177	putative Mg++ binding site [ion binding]; other site
1335916000178	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1335916000179	nucleotide binding region [chemical binding]; other site
1335916000180	ATP-binding site [chemical binding]; other site
1335916000181	DNA polymerase II; Reviewed; Region: PRK05762
1335916000182	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
1335916000183	active site
1335916000184	catalytic site [active]
1335916000185	substrate binding site [chemical binding]; other site
1335916000186	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
1335916000187	active site
1335916000188	metal-binding site
1335916000189	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1335916000190	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1335916000191	intersubunit interface [polypeptide binding]; other site
1335916000192	active site
1335916000193	Zn2+ binding site [ion binding]; other site
1335916000194	L-arabinose isomerase; Provisional; Region: PRK02929
1335916000195	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
1335916000196	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
1335916000197	trimer interface [polypeptide binding]; other site
1335916000198	putative substrate binding site [chemical binding]; other site
1335916000199	putative metal binding site [ion binding]; other site
1335916000200	ribulokinase; Provisional; Region: PRK04123
1335916000201	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1335916000202	N- and C-terminal domain interface [polypeptide binding]; other site
1335916000203	active site
1335916000204	MgATP binding site [chemical binding]; other site
1335916000205	catalytic site [active]
1335916000206	metal binding site [ion binding]; metal-binding site
1335916000207	carbohydrate binding site [chemical binding]; other site
1335916000208	homodimer interface [polypeptide binding]; other site
1335916000209	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
1335916000210	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1335916000211	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916000212	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916000213	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1335916000214	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1335916000215	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1335916000216	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
1335916000217	Walker A/P-loop; other site
1335916000218	ATP binding site [chemical binding]; other site
1335916000219	Q-loop/lid; other site
1335916000220	ABC transporter signature motif; other site
1335916000221	Walker B; other site
1335916000222	D-loop; other site
1335916000223	H-loop/switch region; other site
1335916000224	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
1335916000225	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1335916000226	transcriptional regulator SgrR; Provisional; Region: PRK13626
1335916000227	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1335916000228	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1335916000229	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916000230	sugar efflux transporter; Region: 2A0120; TIGR00899
1335916000231	putative substrate translocation pore; other site
1335916000232	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1335916000233	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1335916000234	substrate binding site [chemical binding]; other site
1335916000235	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1335916000236	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1335916000237	substrate binding site [chemical binding]; other site
1335916000238	ligand binding site [chemical binding]; other site
1335916000239	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1335916000240	tartrate dehydrogenase; Region: TTC; TIGR02089
1335916000241	2-isopropylmalate synthase; Validated; Region: PRK00915
1335916000242	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1335916000243	active site
1335916000244	catalytic residues [active]
1335916000245	metal binding site [ion binding]; metal-binding site
1335916000246	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1335916000247	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1335916000248	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916000249	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
1335916000250	putative substrate binding pocket [chemical binding]; other site
1335916000251	putative dimerization interface [polypeptide binding]; other site
1335916000252	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
1335916000253	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1335916000254	PYR/PP interface [polypeptide binding]; other site
1335916000255	dimer interface [polypeptide binding]; other site
1335916000256	TPP binding site [chemical binding]; other site
1335916000257	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1335916000258	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1335916000259	TPP-binding site [chemical binding]; other site
1335916000260	dimer interface [polypeptide binding]; other site
1335916000261	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1335916000262	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1335916000263	putative valine binding site [chemical binding]; other site
1335916000264	dimer interface [polypeptide binding]; other site
1335916000265	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1335916000266	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
1335916000267	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1335916000268	DNA binding site [nucleotide binding]
1335916000269	domain linker motif; other site
1335916000270	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1335916000271	dimerization interface [polypeptide binding]; other site
1335916000272	ligand binding site [chemical binding]; other site
1335916000273	mraZ protein; Region: TIGR00242
1335916000274	MraZ protein; Region: MraZ; pfam02381
1335916000275	MraZ protein; Region: MraZ; pfam02381
1335916000276	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
1335916000277	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1335916000278	cell division protein FtsL; Provisional; Region: PRK10772
1335916000279	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1335916000280	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1335916000281	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1335916000282	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1335916000283	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1335916000284	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1335916000285	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1335916000286	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1335916000287	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1335916000288	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1335916000289	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1335916000290	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1335916000291	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1335916000292	Mg++ binding site [ion binding]; other site
1335916000293	putative catalytic motif [active]
1335916000294	putative substrate binding site [chemical binding]; other site
1335916000295	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1335916000296	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1335916000297	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1335916000298	cell division protein FtsW; Provisional; Region: PRK10774
1335916000299	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1335916000300	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1335916000301	active site
1335916000302	homodimer interface [polypeptide binding]; other site
1335916000303	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1335916000304	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1335916000305	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1335916000306	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1335916000307	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1335916000308	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1335916000309	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1335916000310	cell division protein FtsQ; Provisional; Region: PRK10775
1335916000311	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1335916000312	Cell division protein FtsQ; Region: FtsQ; pfam03799
1335916000313	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1335916000314	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1335916000315	Cell division protein FtsA; Region: FtsA; pfam14450
1335916000316	cell division protein FtsZ; Validated; Region: PRK09330
1335916000317	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1335916000318	nucleotide binding site [chemical binding]; other site
1335916000319	SulA interaction site; other site
1335916000320	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1335916000321	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1335916000322	SecA regulator SecM; Provisional; Region: PRK02943
1335916000323	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1335916000324	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1335916000325	SEC-C motif; Region: SEC-C; pfam02810
1335916000326	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1335916000327	active site
1335916000328	8-oxo-dGMP binding site [chemical binding]; other site
1335916000329	nudix motif; other site
1335916000330	metal binding site [ion binding]; metal-binding site
1335916000331	DNA gyrase inhibitor; Reviewed; Region: PRK00418
1335916000332	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
1335916000333	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1335916000334	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1335916000335	CoA-binding site [chemical binding]; other site
1335916000336	ATP-binding [chemical binding]; other site
1335916000337	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
1335916000338	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1335916000339	active site
1335916000340	type IV pilin biogenesis protein; Provisional; Region: PRK10573
1335916000341	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1335916000342	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1335916000343	hypothetical protein; Provisional; Region: PRK10436
1335916000344	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1335916000345	Walker A motif; other site
1335916000346	ATP binding site [chemical binding]; other site
1335916000347	Walker B motif; other site
1335916000348	putative major pilin subunit; Provisional; Region: PRK10574
1335916000349	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1335916000350	Pilin (bacterial filament); Region: Pilin; pfam00114
1335916000351	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
1335916000352	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1335916000353	dimerization interface [polypeptide binding]; other site
1335916000354	active site
1335916000355	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1335916000356	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1335916000357	amidase catalytic site [active]
1335916000358	Zn binding residues [ion binding]; other site
1335916000359	substrate binding site [chemical binding]; other site
1335916000360	regulatory protein AmpE; Provisional; Region: PRK10987
1335916000361	aromatic amino acid transporter; Provisional; Region: PRK10238
1335916000362	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1335916000363	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916000364	DNA-binding site [nucleotide binding]; DNA binding site
1335916000365	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1335916000366	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1335916000367	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1335916000368	dimer interface [polypeptide binding]; other site
1335916000369	TPP-binding site [chemical binding]; other site
1335916000370	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1335916000371	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1335916000372	E3 interaction surface; other site
1335916000373	lipoyl attachment site [posttranslational modification]; other site
1335916000374	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1335916000375	E3 interaction surface; other site
1335916000376	lipoyl attachment site [posttranslational modification]; other site
1335916000377	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1335916000378	E3 interaction surface; other site
1335916000379	lipoyl attachment site [posttranslational modification]; other site
1335916000380	e3 binding domain; Region: E3_binding; pfam02817
1335916000381	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1335916000382	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1335916000383	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1335916000384	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916000385	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1335916000386	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1335916000387	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1335916000388	substrate binding site [chemical binding]; other site
1335916000389	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1335916000390	substrate binding site [chemical binding]; other site
1335916000391	ligand binding site [chemical binding]; other site
1335916000392	hypothetical protein; Provisional; Region: PRK05248
1335916000393	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
1335916000394	spermidine synthase; Provisional; Region: PRK00811
1335916000395	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916000396	S-adenosylmethionine binding site [chemical binding]; other site
1335916000397	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1335916000398	multicopper oxidase; Provisional; Region: PRK10965
1335916000399	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1335916000400	Multicopper oxidase; Region: Cu-oxidase; pfam00394
1335916000401	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1335916000402	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1335916000403	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1335916000404	Trp docking motif [polypeptide binding]; other site
1335916000405	putative active site [active]
1335916000406	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1335916000407	active site
1335916000408	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1335916000409	active site clefts [active]
1335916000410	zinc binding site [ion binding]; other site
1335916000411	dimer interface [polypeptide binding]; other site
1335916000412	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1335916000413	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1335916000414	Walker A/P-loop; other site
1335916000415	ATP binding site [chemical binding]; other site
1335916000416	Q-loop/lid; other site
1335916000417	ABC transporter signature motif; other site
1335916000418	Walker B; other site
1335916000419	D-loop; other site
1335916000420	H-loop/switch region; other site
1335916000421	inner membrane transport permease; Provisional; Region: PRK15066
1335916000422	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1335916000423	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1335916000424	active pocket/dimerization site; other site
1335916000425	active site
1335916000426	phosphorylation site [posttranslational modification]
1335916000427	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
1335916000428	putative active site [active]
1335916000429	putative metal binding site [ion binding]; other site
1335916000430	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1335916000431	tetramerization interface [polypeptide binding]; other site
1335916000432	active site
1335916000433	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1335916000434	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1335916000435	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1335916000436	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1335916000437	active site
1335916000438	ATP-binding site [chemical binding]; other site
1335916000439	pantoate-binding site; other site
1335916000440	HXXH motif; other site
1335916000441	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1335916000442	oligomerization interface [polypeptide binding]; other site
1335916000443	active site
1335916000444	metal binding site [ion binding]; metal-binding site
1335916000445	putative fimbrial-like adhesin protein; Provisional; Region: PRK09723
1335916000446	putative fimbrial protein StaF; Provisional; Region: PRK15262
1335916000447	putative fimbrial protein StaE; Provisional; Region: PRK15263
1335916000448	Fimbrial protein; Region: Fimbrial; cl01416
1335916000449	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
1335916000450	PapC N-terminal domain; Region: PapC_N; pfam13954
1335916000451	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1335916000452	PapC C-terminal domain; Region: PapC_C; pfam13953
1335916000453	putative chaperone protein EcpD; Provisional; Region: PRK09926
1335916000454	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1335916000455	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1335916000456	Fimbrial protein; Region: Fimbrial; cl01416
1335916000457	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1335916000458	catalytic center binding site [active]
1335916000459	ATP binding site [chemical binding]; other site
1335916000460	poly(A) polymerase; Region: pcnB; TIGR01942
1335916000461	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1335916000462	active site
1335916000463	NTP binding site [chemical binding]; other site
1335916000464	metal binding triad [ion binding]; metal-binding site
1335916000465	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1335916000466	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1335916000467	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1335916000468	tRNA synthetases class I (E and Q), catalytic domain; Region: tRNA-synt_1c; pfam00749
1335916000469	active site
1335916000470	nucleotide binding site [chemical binding]; other site
1335916000471	HIGH motif; other site
1335916000472	KMSKS motif; other site
1335916000473	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
1335916000474	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1335916000475	2'-5' RNA ligase; Provisional; Region: PRK15124
1335916000476	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1335916000477	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1335916000478	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1335916000479	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1335916000480	ATP binding site [chemical binding]; other site
1335916000481	putative Mg++ binding site [ion binding]; other site
1335916000482	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1335916000483	nucleotide binding region [chemical binding]; other site
1335916000484	ATP-binding site [chemical binding]; other site
1335916000485	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
1335916000486	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1335916000487	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
1335916000488	Transglycosylase; Region: Transgly; pfam00912
1335916000489	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1335916000490	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1335916000491	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1335916000492	N-terminal plug; other site
1335916000493	ligand-binding site [chemical binding]; other site
1335916000494	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
1335916000495	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1335916000496	Walker A/P-loop; other site
1335916000497	ATP binding site [chemical binding]; other site
1335916000498	Q-loop/lid; other site
1335916000499	ABC transporter signature motif; other site
1335916000500	Walker B; other site
1335916000501	D-loop; other site
1335916000502	H-loop/switch region; other site
1335916000503	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1335916000504	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1335916000505	siderophore binding site; other site
1335916000506	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1335916000507	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1335916000508	ABC-ATPase subunit  interface; other site
1335916000509	dimer interface [polypeptide binding]; other site
1335916000510	putative PBP binding regions; other site
1335916000511	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1335916000512	ABC-ATPase subunit  interface; other site
1335916000513	dimer interface [polypeptide binding]; other site
1335916000514	putative PBP binding regions; other site
1335916000515	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1335916000516	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1335916000517	inhibitor-cofactor binding pocket; inhibition site
1335916000518	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916000519	catalytic residue [active]
1335916000520	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1335916000521	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1335916000522	Cl- selectivity filter; other site
1335916000523	Cl- binding residues [ion binding]; other site
1335916000524	pore gating glutamate residue; other site
1335916000525	dimer interface [polypeptide binding]; other site
1335916000526	H+/Cl- coupling transport residue; other site
1335916000527	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1335916000528	hypothetical protein; Provisional; Region: PRK10578
1335916000529	UPF0126 domain; Region: UPF0126; pfam03458
1335916000530	UPF0126 domain; Region: UPF0126; pfam03458
1335916000531	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
1335916000532	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1335916000533	cobalamin binding residues [chemical binding]; other site
1335916000534	putative BtuC binding residues; other site
1335916000535	dimer interface [polypeptide binding]; other site
1335916000536	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1335916000537	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1335916000538	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
1335916000539	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1335916000540	Zn2+ binding site [ion binding]; other site
1335916000541	Mg2+ binding site [ion binding]; other site
1335916000542	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1335916000543	serine endoprotease; Provisional; Region: PRK10942
1335916000544	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1335916000545	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1335916000546	protein binding site [polypeptide binding]; other site
1335916000547	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1335916000548	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
1335916000549	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1335916000550	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1335916000551	hypothetical protein; Provisional; Region: PRK13677
1335916000552	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1335916000553	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1335916000554	trimer interface [polypeptide binding]; other site
1335916000555	active site
1335916000556	substrate binding site [chemical binding]; other site
1335916000557	CoA binding site [chemical binding]; other site
1335916000558	PII uridylyl-transferase; Provisional; Region: PRK05007
1335916000559	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1335916000560	metal binding triad; other site
1335916000561	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1335916000562	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1335916000563	Zn2+ binding site [ion binding]; other site
1335916000564	Mg2+ binding site [ion binding]; other site
1335916000565	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1335916000566	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1335916000567	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1335916000568	active site
1335916000569	elongation factor Ts; Provisional; Region: tsf; PRK09377
1335916000570	UBA/TS-N domain; Region: UBA; pfam00627
1335916000571	Elongation factor TS; Region: EF_TS; pfam00889
1335916000572	Elongation factor TS; Region: EF_TS; pfam00889
1335916000573	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1335916000574	putative nucleotide binding site [chemical binding]; other site
1335916000575	uridine monophosphate binding site [chemical binding]; other site
1335916000576	homohexameric interface [polypeptide binding]; other site
1335916000577	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1335916000578	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1335916000579	hinge region; other site
1335916000580	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1335916000581	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1335916000582	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1335916000583	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1335916000584	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1335916000585	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1335916000586	catalytic residue [active]
1335916000587	putative FPP diphosphate  binding site; other site
1335916000588	putative FPP binding hydrophobic cleft; other site
1335916000589	dimer interface [polypeptide binding]; other site
1335916000590	putative IPP diphosphate binding site; other site
1335916000591	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1335916000592	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1335916000593	zinc metallopeptidase RseP; Provisional; Region: PRK10779
1335916000594	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1335916000595	active site
1335916000596	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1335916000597	protein binding site [polypeptide binding]; other site
1335916000598	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1335916000599	putative substrate binding region [chemical binding]; other site
1335916000600	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1335916000601	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1335916000602	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1335916000603	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1335916000604	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1335916000605	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1335916000606	Surface antigen; Region: Bac_surface_Ag; pfam01103
1335916000607	periplasmic chaperone; Provisional; Region: PRK10780
1335916000608	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1335916000609	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1335916000610	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1335916000611	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1335916000612	trimer interface [polypeptide binding]; other site
1335916000613	active site
1335916000614	UDP-GlcNAc binding site [chemical binding]; other site
1335916000615	lipid binding site [chemical binding]; lipid-binding site
1335916000616	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1335916000617	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1335916000618	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1335916000619	active site
1335916000620	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1335916000621	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1335916000622	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1335916000623	RNA/DNA hybrid binding site [nucleotide binding]; other site
1335916000624	active site
1335916000625	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1335916000626	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1335916000627	putative active site [active]
1335916000628	putative PHP Thumb interface [polypeptide binding]; other site
1335916000629	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1335916000630	generic binding surface II; other site
1335916000631	generic binding surface I; other site
1335916000632	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1335916000633	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1335916000634	lysine decarboxylase LdcC; Provisional; Region: PRK15399
1335916000635	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1335916000636	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1335916000637	homodimer interface [polypeptide binding]; other site
1335916000638	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916000639	catalytic residue [active]
1335916000640	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1335916000641	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1335916000642	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1335916000643	putative metal binding site [ion binding]; other site
1335916000644	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1335916000645	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1335916000646	Ligand Binding Site [chemical binding]; other site
1335916000647	TilS substrate binding domain; Region: TilS; pfam09179
1335916000648	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1335916000649	Rho-binding antiterminator; Provisional; Region: PRK11625
1335916000650	hypothetical protein; Provisional; Region: PRK04964
1335916000651	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
1335916000652	hypothetical protein; Provisional; Region: PRK09256
1335916000653	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1335916000654	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
1335916000655	NlpE N-terminal domain; Region: NlpE; pfam04170
1335916000656	hypothetical protein; Provisional; Region: PRK11479
1335916000657	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
1335916000658	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1335916000659	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1335916000660	dimer interface [polypeptide binding]; other site
1335916000661	motif 1; other site
1335916000662	active site
1335916000663	motif 2; other site
1335916000664	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1335916000665	putative deacylase active site [active]
1335916000666	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1335916000667	active site
1335916000668	motif 3; other site
1335916000669	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1335916000670	anticodon binding site; other site
1335916000671	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1335916000672	homodimer interaction site [polypeptide binding]; other site
1335916000673	cofactor binding site; other site
1335916000674	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
1335916000675	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1335916000676	lipoprotein, YaeC family; Region: TIGR00363
1335916000677	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916000678	dimer interface [polypeptide binding]; other site
1335916000679	conserved gate region; other site
1335916000680	ABC-ATPase subunit interface; other site
1335916000681	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1335916000682	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1335916000683	Walker A/P-loop; other site
1335916000684	ATP binding site [chemical binding]; other site
1335916000685	Q-loop/lid; other site
1335916000686	ABC transporter signature motif; other site
1335916000687	Walker B; other site
1335916000688	D-loop; other site
1335916000689	H-loop/switch region; other site
1335916000690	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1335916000691	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
1335916000692	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916000693	active site
1335916000694	motif I; other site
1335916000695	motif II; other site
1335916000696	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1335916000697	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1335916000698	active site
1335916000699	catalytic tetrad [active]
1335916000700	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1335916000701	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916000702	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
1335916000703	putative effector binding pocket; other site
1335916000704	dimerization interface [polypeptide binding]; other site
1335916000705	hypothetical protein; Provisional; Region: PRK05421
1335916000706	putative catalytic site [active]
1335916000707	putative metal binding site [ion binding]; other site
1335916000708	putative phosphate binding site [ion binding]; other site
1335916000709	putative catalytic site [active]
1335916000710	putative phosphate binding site [ion binding]; other site
1335916000711	putative metal binding site [ion binding]; other site
1335916000712	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1335916000713	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916000714	S-adenosylmethionine binding site [chemical binding]; other site
1335916000715	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
1335916000716	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1335916000717	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1335916000718	catalytic residue [active]
1335916000719	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1335916000720	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1335916000721	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
1335916000722	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916000723	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1335916000724	RNA/DNA hybrid binding site [nucleotide binding]; other site
1335916000725	active site
1335916000726	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1335916000727	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1335916000728	active site
1335916000729	catalytic site [active]
1335916000730	substrate binding site [chemical binding]; other site
1335916000731	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1335916000732	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1335916000733	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1335916000734	ImpA domain protein; Region: DUF3702; pfam12486
1335916000735	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1335916000736	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
1335916000737	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1335916000738	type VI secretion-associated protein, VC_A0118 family; Region: VI_minor_1; TIGR03360
1335916000739	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1335916000740	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916000741	Walker A motif; other site
1335916000742	ATP binding site [chemical binding]; other site
1335916000743	Walker B motif; other site
1335916000744	arginine finger; other site
1335916000745	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916000746	Walker A motif; other site
1335916000747	ATP binding site [chemical binding]; other site
1335916000748	Walker B motif; other site
1335916000749	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1335916000750	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
1335916000751	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
1335916000752	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1335916000753	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
1335916000754	Predicted component of the type VI protein secretion system, contains a FHA domain [Intracellular trafficking, secretion, and vesicular    transport; Signal transduction mechanisms]; Region: COG3456
1335916000755	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
1335916000756	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1335916000757	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1335916000758	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
1335916000759	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
1335916000760	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1335916000761	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
1335916000762	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
1335916000763	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1335916000764	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1335916000765	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1335916000766	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1335916000767	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1335916000768	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1335916000769	RHS Repeat; Region: RHS_repeat; pfam05593
1335916000770	RHS Repeat; Region: RHS_repeat; pfam05593
1335916000771	RHS Repeat; Region: RHS_repeat; pfam05593
1335916000772	RHS Repeat; Region: RHS_repeat; pfam05593
1335916000773	RHS Repeat; Region: RHS_repeat; cl11982
1335916000774	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1335916000775	RHS Repeat; Region: RHS_repeat; pfam05593
1335916000776	RHS Repeat; Region: RHS_repeat; pfam05593
1335916000777	RHS protein; Region: RHS; pfam03527
1335916000778	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1335916000779	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1335916000780	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1335916000781	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916000782	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1335916000783	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1335916000784	C-N hydrolase family amidase; Provisional; Region: PRK10438
1335916000785	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1335916000786	putative active site [active]
1335916000787	catalytic triad [active]
1335916000788	dimer interface [polypeptide binding]; other site
1335916000789	multimer interface [polypeptide binding]; other site
1335916000790	C-lysozyme inhibitor; Provisional; Region: PRK09993
1335916000791	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
1335916000792	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1335916000793	active site
1335916000794	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
1335916000795	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1335916000796	dimer interface [polypeptide binding]; other site
1335916000797	active site
1335916000798	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
1335916000799	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1335916000800	putative active site [active]
1335916000801	putative dimer interface [polypeptide binding]; other site
1335916000802	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1335916000803	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1335916000804	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
1335916000805	RelB antitoxin; Region: RelB; cl01171
1335916000806	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1335916000807	NlpC/P60 family; Region: NLPC_P60; pfam00877
1335916000808	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
1335916000809	HicB family; Region: HicB; pfam05534
1335916000810	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1335916000811	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1335916000812	Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliR; COG1684
1335916000813	Bacterial export proteins, family 3; Region: Bac_export_3; cl00867
1335916000814	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1335916000815	flagellar motor switch protein FliN; Region: fliN; TIGR02480
1335916000816	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1335916000817	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
1335916000818	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916000819	Walker A motif; other site
1335916000820	ATP binding site [chemical binding]; other site
1335916000821	Walker B motif; other site
1335916000822	arginine finger; other site
1335916000823	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1335916000824	Flagellar hook-basal body complex protein FliE; Region: FliE; pfam02049
1335916000825	flagellar motor switch protein G; Reviewed; Region: fliG; PRK07194
1335916000826	MgtE intracellular N domain; Region: MgtE_N; smart00924
1335916000827	FliG C-terminal domain; Region: FliG_C; pfam01706
1335916000828	flagellar assembly protein H; Provisional; Region: fliH; PRK13386
1335916000829	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
1335916000830	Flagellar assembly protein FliH; Region: FliH; pfam02108
1335916000831	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07196
1335916000832	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1335916000833	Walker A motif/ATP binding site; other site
1335916000834	Walker B motif; other site
1335916000835	flagellar export protein FliJ; Region: flagell_FliJ; TIGR02473
1335916000836	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1335916000837	active site
1335916000838	nucleotide binding site [chemical binding]; other site
1335916000839	HIGH motif; other site
1335916000840	KMSKS motif; other site
1335916000841	multiple promoter invertase; Provisional; Region: mpi; PRK13413
1335916000842	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1335916000843	catalytic residues [active]
1335916000844	catalytic nucleophile [active]
1335916000845	Presynaptic Site I dimer interface [polypeptide binding]; other site
1335916000846	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1335916000847	Synaptic Flat tetramer interface [polypeptide binding]; other site
1335916000848	Synaptic Site I dimer interface [polypeptide binding]; other site
1335916000849	DNA binding site [nucleotide binding]
1335916000850	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1335916000851	DNA-binding interface [nucleotide binding]; DNA binding site
1335916000852	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1335916000853	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1335916000854	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1335916000855	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; cl01542
1335916000856	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
1335916000857	Phage protein GP46; Region: GP46; pfam07409
1335916000858	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1335916000859	Bacteriophage Mu Gp45 protein; Region: Phage_Mu_Gp45; pfam06890
1335916000860	Mu-like prophage tail protein gpP [General function prediction only]; Region: COG4379
1335916000861	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1335916000862	Mu-like prophage DNA circulation protein [General function prediction only]; Region: COG4228
1335916000863	DNA circulation protein N-terminus; Region: DNA_circ_N; pfam07157
1335916000864	Mu-like prophage protein [General function prediction only]; Region: COG3941
1335916000865	tape measure domain; Region: tape_meas_nterm; TIGR02675
1335916000866	Mu-like prophage FluMu protein gp41 [Function unknown]; Region: COG4518
1335916000867	Phage tail tube protein; Region: Tail_tube; pfam10618
1335916000868	Mu-like prophage tail sheath protein gpL [General function prediction only]; Region: COG4386
1335916000869	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
1335916000870	Protein of unknown function (DUF2635); Region: DUF2635; pfam10948
1335916000871	Domain of unknown function (DUF1834); Region: DUF1834; pfam08873
1335916000872	Protein of unknown function (DUF1320); Region: DUF1320; pfam07030
1335916000873	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; pfam10124
1335916000874	Mu-like prophage I protein; Region: Mu-like_Pro; pfam10123
1335916000875	phage virion morphogenesis (putative tail completion) protein; Region: tail_comp_S; TIGR01635
1335916000876	Uncharacterized protein, homolog of phage Mu protein gp30 [Function unknown]; Region: COG2369
1335916000877	Phage Mu protein F like protein; Region: Phage_Mu_F; pfam04233
1335916000878	Protein of unknown function (DUF935); Region: DUF935; pfam06074
1335916000879	Mu-like prophage protein gp29 [Function unknown]; Region: COG4383
1335916000880	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
1335916000881	Protein of unknown function (DUF3486); Region: DUF3486; pfam11985
1335916000882	Protein of unknown function (DUF2730); Region: DUF2730; pfam10805
1335916000883	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1335916000884	catalytic residues [active]
1335916000885	Mor transcription activator family; Region: Mor; pfam08765
1335916000886	Mor transcription activator family; Region: Mor; pfam08765
1335916000887	Protein of unknown function (DUF1018); Region: DUF1018; pfam06252
1335916000888	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1335916000889	Bacteriophage Mu Gam like protein; Region: Phage_Mu_Gam; cl01825
1335916000890	Uncharacterized ATPase, putative transposase [General function prediction only]; Region: COG2842
1335916000891	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1335916000892	Walker A motif; other site
1335916000893	ATP binding site [chemical binding]; other site
1335916000894	Walker B motif; other site
1335916000895	Mu B transposition protein, C terminal; Region: Phage-MuB_C; pfam09077
1335916000896	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
1335916000897	Mu DNA binding, I gamma subdomain; Region: HTH_Tnp_Mu_2; pfam09039
1335916000898	Bacteriophage Mu transposase; Region: DDE_2; pfam02914
1335916000899	Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299
1335916000900	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
1335916000901	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
1335916000902	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1335916000903	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1335916000904	active site
1335916000905	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
1335916000906	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
1335916000907	FlgN protein; Region: FlgN; pfam05130
1335916000908	Anti-sigma-28 factor, FlgM; Region: FlgM; pfam04316
1335916000909	SAF-like; Region: SAF_2; pfam13144
1335916000910	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1335916000911	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
1335916000912	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1335916000913	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK12685
1335916000914	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK06802
1335916000915	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1335916000916	Flagellar hook capping protein [Cell motility and secretion]; Region: FlgD; COG1843
1335916000917	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1335916000918	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1335916000919	flagellar hook protein FlgE; Validated; Region: flgE; PRK06803
1335916000920	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1335916000921	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1335916000922	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1335916000923	flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640
1335916000924	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1335916000925	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1335916000926	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1335916000927	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1335916000928	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK12407
1335916000929	Flagellar L-ring protein; Region: FlgH; pfam02107
1335916000930	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1335916000931	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1335916000932	Rod binding protein; Region: Rod-binding; cl01626
1335916000933	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK07191
1335916000934	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1335916000935	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK07192
1335916000936	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1335916000937	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1335916000938	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1335916000939	DNA binding site [nucleotide binding]
1335916000940	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916000941	flagellin; Reviewed; Region: PRK08869
1335916000942	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1335916000943	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1335916000944	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1335916000945	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1335916000946	Flagellar protein FliS; Region: FliS; cl00654
1335916000947	adenylate kinase; Region: PLN02674
1335916000948	Flagellar basal body-associated protein FliL; Region: FliL; pfam03748
1335916000949	flagellar biosynthesis sigma factor; Provisional; Region: PRK12427
1335916000950	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1335916000951	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1335916000952	DNA binding residues [nucleotide binding]
1335916000953	flagellar motor protein MotA; Provisional; Region: PRK12482
1335916000954	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1335916000955	hypothetical protein; Validated; Region: PRK06778
1335916000956	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1335916000957	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1335916000958	ligand binding site [chemical binding]; other site
1335916000959	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1335916000960	active site
1335916000961	DNA polymerase IV; Validated; Region: PRK02406
1335916000962	DNA binding site [nucleotide binding]
1335916000963	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1335916000964	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1335916000965	Coenzyme A binding pocket [chemical binding]; other site
1335916000966	hypothetical protein; Reviewed; Region: PRK09588
1335916000967	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
1335916000968	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
1335916000969	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1335916000970	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1335916000971	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1335916000972	metal binding site [ion binding]; metal-binding site
1335916000973	dimer interface [polypeptide binding]; other site
1335916000974	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1335916000975	active site
1335916000976	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
1335916000977	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
1335916000978	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1335916000979	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1335916000980	trimer interface [polypeptide binding]; other site
1335916000981	eyelet of channel; other site
1335916000982	gamma-glutamyl kinase; Provisional; Region: PRK05429
1335916000983	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1335916000984	nucleotide binding site [chemical binding]; other site
1335916000985	homotetrameric interface [polypeptide binding]; other site
1335916000986	putative phosphate binding site [ion binding]; other site
1335916000987	putative allosteric binding site; other site
1335916000988	PUA domain; Region: PUA; pfam01472
1335916000989	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1335916000990	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1335916000991	putative catalytic cysteine [active]
1335916000992	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1335916000993	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1335916000994	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
1335916000995	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
1335916000996	XdhC Rossmann domain; Region: XdhC_C; pfam13478
1335916000997	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
1335916000998	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
1335916000999	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1335916001000	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
1335916001001	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
1335916001002	aldehyde oxidoreductase 2Fe-2S subunit; Provisional; Region: PRK11433
1335916001003	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1335916001004	catalytic loop [active]
1335916001005	iron binding site [ion binding]; other site
1335916001006	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1335916001007	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1335916001008	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1335916001009	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
1335916001010	putative fimbrial protein TcfA; Provisional; Region: PRK15308
1335916001011	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1335916001012	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916001013	DNA binding residues [nucleotide binding]
1335916001014	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1335916001015	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1335916001016	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1335916001017	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1335916001018	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1335916001019	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1335916001020	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1335916001021	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1335916001022	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916001023	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
1335916001024	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1335916001025	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1335916001026	active site
1335916001027	catalytic tetrad [active]
1335916001028	Predicted membrane protein [Function unknown]; Region: COG3059
1335916001029	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1335916001030	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
1335916001031	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1335916001032	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916001033	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1335916001034	Cupin; Region: Cupin_6; pfam12852
1335916001035	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1335916001036	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916001037	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1335916001038	Cysteine-rich domain; Region: CCG; pfam02754
1335916001039	Cysteine-rich domain; Region: CCG; pfam02754
1335916001040	iron-sulfur cluster-binding protein; Region: TIGR00273
1335916001041	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1335916001042	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1335916001043	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
1335916001044	Uncharacterized conserved protein [Function unknown]; Region: COG1556
1335916001045	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1335916001046	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
1335916001047	NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090
1335916001048	tetrameric interface [polypeptide binding]; other site
1335916001049	NAD binding site [chemical binding]; other site
1335916001050	catalytic residues [active]
1335916001051	transcriptional regulator BetI; Validated; Region: PRK00767
1335916001052	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1335916001053	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1335916001054	choline transport protein BetT; Provisional; Region: PRK09928
1335916001055	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1335916001056	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1335916001057	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1335916001058	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1335916001059	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916001060	DNA binding residues [nucleotide binding]
1335916001061	dimerization interface [polypeptide binding]; other site
1335916001062	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1335916001063	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
1335916001064	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916001065	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1335916001066	dimerization interface [polypeptide binding]; other site
1335916001067	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1335916001068	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1335916001069	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1335916001070	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1335916001071	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
1335916001072	CoA binding domain; Region: CoA_binding; pfam02629
1335916001073	CoA-ligase; Region: Ligase_CoA; pfam00549
1335916001074	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
1335916001075	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1335916001076	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1335916001077	putative substrate binding site [chemical binding]; other site
1335916001078	nucleotide binding site [chemical binding]; other site
1335916001079	nucleotide binding site [chemical binding]; other site
1335916001080	homodimer interface [polypeptide binding]; other site
1335916001081	putative deaminase; Validated; Region: PRK06846
1335916001082	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1335916001083	active site
1335916001084	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1335916001085	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1335916001086	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1335916001087	ligand binding site [chemical binding]; other site
1335916001088	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1335916001089	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1335916001090	Walker A/P-loop; other site
1335916001091	ATP binding site [chemical binding]; other site
1335916001092	Q-loop/lid; other site
1335916001093	ABC transporter signature motif; other site
1335916001094	Walker B; other site
1335916001095	D-loop; other site
1335916001096	H-loop/switch region; other site
1335916001097	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1335916001098	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1335916001099	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1335916001100	TM-ABC transporter signature motif; other site
1335916001101	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1335916001102	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1335916001103	TM-ABC transporter signature motif; other site
1335916001104	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1335916001105	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1335916001106	putative NAD(P) binding site [chemical binding]; other site
1335916001107	putative substrate binding site [chemical binding]; other site
1335916001108	catalytic Zn binding site [ion binding]; other site
1335916001109	structural Zn binding site [ion binding]; other site
1335916001110	dimer interface [polypeptide binding]; other site
1335916001111	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
1335916001112	hypothetical protein; Provisional; Region: PRK09929
1335916001113	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
1335916001114	Propionate catabolism activator; Region: PrpR_N; pfam06506
1335916001115	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916001116	Walker A motif; other site
1335916001117	ATP binding site [chemical binding]; other site
1335916001118	Walker B motif; other site
1335916001119	arginine finger; other site
1335916001120	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1335916001121	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1335916001122	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1335916001123	tetramer interface [polypeptide binding]; other site
1335916001124	active site
1335916001125	Mg2+/Mn2+ binding site [ion binding]; other site
1335916001126	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1335916001127	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
1335916001128	dimer interface [polypeptide binding]; other site
1335916001129	active site
1335916001130	citrylCoA binding site [chemical binding]; other site
1335916001131	oxalacetate/citrate binding site [chemical binding]; other site
1335916001132	coenzyme A binding site [chemical binding]; other site
1335916001133	catalytic triad [active]
1335916001134	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
1335916001135	2-methylcitrate dehydratase; Region: prpD; TIGR02330
1335916001136	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
1335916001137	Propionyl-CoA synthetase (PrpE); Region: PrpE; cd05967
1335916001138	acyl-activating enzyme (AAE) consensus motif; other site
1335916001139	putative AMP binding site [chemical binding]; other site
1335916001140	putative active site [active]
1335916001141	putative CoA binding site [chemical binding]; other site
1335916001142	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
1335916001143	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1335916001144	Na binding site [ion binding]; other site
1335916001145	putative substrate binding site [chemical binding]; other site
1335916001146	cytosine deaminase; Provisional; Region: PRK09230
1335916001147	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1335916001148	active site
1335916001149	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
1335916001150	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916001151	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator CynR, contains the type 2 periplasmic binding fold; Region: PBP2_CynR; cd08425
1335916001152	dimerization interface [polypeptide binding]; other site
1335916001153	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
1335916001154	active site clefts [active]
1335916001155	zinc binding site [ion binding]; other site
1335916001156	dimer interface [polypeptide binding]; other site
1335916001157	Cyanate lyase [Inorganic ion transport and metabolism]; Region: CynS; COG1513
1335916001158	Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate.  It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the...; Region: Cyanase_C; cd00559
1335916001159	oligomer interface [polypeptide binding]; other site
1335916001160	active site
1335916001161	putative cyanate transporter; Provisional; Region: cynX; PRK09705
1335916001162	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916001163	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
1335916001164	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1335916001165	active site
1335916001166	substrate binding site [chemical binding]; other site
1335916001167	trimer interface [polypeptide binding]; other site
1335916001168	CoA binding site [chemical binding]; other site
1335916001169	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
1335916001170	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916001171	putative substrate translocation pore; other site
1335916001172	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
1335916001173	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1335916001174	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1335916001175	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1335916001176	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
1335916001177	lac repressor; Reviewed; Region: lacI; PRK09526
1335916001178	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1335916001179	DNA binding site [nucleotide binding]
1335916001180	domain linker motif; other site
1335916001181	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
1335916001182	ligand binding site [chemical binding]; other site
1335916001183	dimerization interface (open form) [polypeptide binding]; other site
1335916001184	dimerization interface (closed form) [polypeptide binding]; other site
1335916001185	DNA-binding transcriptional activator MhpR; Provisional; Region: PRK09834
1335916001186	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1335916001187	Bacterial transcriptional regulator; Region: IclR; pfam01614
1335916001188	3-(3-hydroxyphenyl)propionate hydroxylase; Validated; Region: mhpA; PRK06183
1335916001189	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1335916001190	Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate; Region: MhpB_like; cd07365
1335916001191	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1335916001192	putative active site [active]
1335916001193	Fe(II) binding site [ion binding]; other site
1335916001194	putative dimer interface [polypeptide binding]; other site
1335916001195	putative tetramer interface [polypeptide binding]; other site
1335916001196	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Region: biphenyl_bphD; TIGR03343
1335916001197	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
1335916001198	nucleophilic elbow; other site
1335916001199	catalytic triad; other site
1335916001200	2-keto-4-pentenoate hydratase; Provisional; Region: mhpD; PRK11342
1335916001201	acetaldehyde dehydrogenase; Validated; Region: PRK08300
1335916001202	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1335916001203	Prokaryotic acetaldehyde dehydrogenase, dimerisation; Region: AcetDehyd-dimer; pfam09290
1335916001204	4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195
1335916001205	4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943
1335916001206	active site
1335916001207	catalytic residues [active]
1335916001208	metal binding site [ion binding]; metal-binding site
1335916001209	DmpG-like communication domain; Region: DmpG_comm; pfam07836
1335916001210	putative 3-hydroxyphenylpropionic transporter MhpT; Provisional; Region: PRK11551
1335916001211	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916001212	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916001213	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
1335916001214	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1335916001215	S-formylglutathione hydrolase; Region: PLN02442
1335916001216	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
1335916001217	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
1335916001218	substrate binding site [chemical binding]; other site
1335916001219	catalytic Zn binding site [ion binding]; other site
1335916001220	NAD binding site [chemical binding]; other site
1335916001221	structural Zn binding site [ion binding]; other site
1335916001222	dimer interface [polypeptide binding]; other site
1335916001223	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1335916001224	putative metal binding site [ion binding]; other site
1335916001225	putative homodimer interface [polypeptide binding]; other site
1335916001226	putative homotetramer interface [polypeptide binding]; other site
1335916001227	putative homodimer-homodimer interface [polypeptide binding]; other site
1335916001228	putative allosteric switch controlling residues; other site
1335916001229	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1335916001230	putative trimer interface [polypeptide binding]; other site
1335916001231	putative CoA binding site [chemical binding]; other site
1335916001232	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916001233	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
1335916001234	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
1335916001235	DXD motif; other site
1335916001236	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
1335916001237	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
1335916001238	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916001239	substrate binding pocket [chemical binding]; other site
1335916001240	membrane-bound complex binding site; other site
1335916001241	hinge residues; other site
1335916001242	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
1335916001243	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1335916001244	Walker A/P-loop; other site
1335916001245	ATP binding site [chemical binding]; other site
1335916001246	Q-loop/lid; other site
1335916001247	ABC transporter signature motif; other site
1335916001248	Walker B; other site
1335916001249	D-loop; other site
1335916001250	H-loop/switch region; other site
1335916001251	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1335916001252	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916001253	dimer interface [polypeptide binding]; other site
1335916001254	conserved gate region; other site
1335916001255	putative PBP binding loops; other site
1335916001256	ABC-ATPase subunit interface; other site
1335916001257	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
1335916001258	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
1335916001259	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1335916001260	dimer interface [polypeptide binding]; other site
1335916001261	active site
1335916001262	Schiff base residues; other site
1335916001263	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916001264	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
1335916001265	dimer interface [polypeptide binding]; other site
1335916001266	Alkaline phosphatase homologues; Region: alkPPc; smart00098
1335916001267	active site
1335916001268	hypothetical protein; Provisional; Region: PRK11505
1335916001269	psiF repeat; Region: PsiF_repeat; pfam07769
1335916001270	psiF repeat; Region: PsiF_repeat; pfam07769
1335916001271	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
1335916001272	MASE2 domain; Region: MASE2; pfam05230
1335916001273	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1335916001274	metal binding site [ion binding]; metal-binding site
1335916001275	active site
1335916001276	I-site; other site
1335916001277	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1335916001278	pyrroline-5-carboxylate reductase; Region: PLN02688
1335916001279	hypothetical protein; Validated; Region: PRK00124
1335916001280	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1335916001281	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1335916001282	ADP binding site [chemical binding]; other site
1335916001283	magnesium binding site [ion binding]; other site
1335916001284	putative shikimate binding site; other site
1335916001285	hypothetical protein; Provisional; Region: PRK10380
1335916001286	hypothetical protein; Provisional; Region: PRK10481
1335916001287	hypothetical protein; Provisional; Region: PRK10579
1335916001288	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
1335916001289	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
1335916001290	fructokinase; Reviewed; Region: PRK09557
1335916001291	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1335916001292	nucleotide binding site [chemical binding]; other site
1335916001293	MFS transport protein AraJ; Provisional; Region: PRK10091
1335916001294	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916001295	putative substrate translocation pore; other site
1335916001296	exonuclease subunit SbcC; Provisional; Region: PRK10246
1335916001297	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916001298	Walker A/P-loop; other site
1335916001299	ATP binding site [chemical binding]; other site
1335916001300	Q-loop/lid; other site
1335916001301	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916001302	ABC transporter signature motif; other site
1335916001303	Walker B; other site
1335916001304	D-loop; other site
1335916001305	H-loop/switch region; other site
1335916001306	exonuclease subunit SbcD; Provisional; Region: PRK10966
1335916001307	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1335916001308	active site
1335916001309	metal binding site [ion binding]; metal-binding site
1335916001310	DNA binding site [nucleotide binding]
1335916001311	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1335916001312	transcriptional regulator PhoB; Provisional; Region: PRK10161
1335916001313	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916001314	active site
1335916001315	phosphorylation site [posttranslational modification]
1335916001316	intermolecular recognition site; other site
1335916001317	dimerization interface [polypeptide binding]; other site
1335916001318	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1335916001319	DNA binding site [nucleotide binding]
1335916001320	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
1335916001321	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
1335916001322	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1335916001323	putative active site [active]
1335916001324	heme pocket [chemical binding]; other site
1335916001325	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916001326	dimer interface [polypeptide binding]; other site
1335916001327	phosphorylation site [posttranslational modification]
1335916001328	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916001329	ATP binding site [chemical binding]; other site
1335916001330	Mg2+ binding site [ion binding]; other site
1335916001331	G-X-G motif; other site
1335916001332	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
1335916001333	putative proline-specific permease; Provisional; Region: proY; PRK10580
1335916001334	Spore germination protein; Region: Spore_permease; cl17796
1335916001335	maltodextrin glucosidase; Provisional; Region: PRK10785
1335916001336	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
1335916001337	homodimer interface [polypeptide binding]; other site
1335916001338	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1335916001339	active site
1335916001340	homodimer interface [polypeptide binding]; other site
1335916001341	catalytic site [active]
1335916001342	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
1335916001343	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1335916001344	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1335916001345	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1335916001346	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
1335916001347	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1335916001348	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1335916001349	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1335916001350	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1335916001351	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1335916001352	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1335916001353	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1335916001354	Protein export membrane protein; Region: SecD_SecF; pfam02355
1335916001355	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1335916001356	active site
1335916001357	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
1335916001358	hypothetical protein; Provisional; Region: PRK11530
1335916001359	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1335916001360	ATP cone domain; Region: ATP-cone; pfam03477
1335916001361	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1335916001362	homopentamer interface [polypeptide binding]; other site
1335916001363	active site
1335916001364	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1335916001365	putative RNA binding site [nucleotide binding]; other site
1335916001366	thiamine monophosphate kinase; Provisional; Region: PRK05731
1335916001367	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1335916001368	ATP binding site [chemical binding]; other site
1335916001369	dimerization interface [polypeptide binding]; other site
1335916001370	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1335916001371	tetramer interfaces [polypeptide binding]; other site
1335916001372	binuclear metal-binding site [ion binding]; other site
1335916001373	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1335916001374	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1335916001375	active site
1335916001376	catalytic tetrad [active]
1335916001377	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
1335916001378	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1335916001379	TPP-binding site; other site
1335916001380	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1335916001381	PYR/PP interface [polypeptide binding]; other site
1335916001382	dimer interface [polypeptide binding]; other site
1335916001383	TPP binding site [chemical binding]; other site
1335916001384	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1335916001385	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1335916001386	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1335916001387	substrate binding pocket [chemical binding]; other site
1335916001388	chain length determination region; other site
1335916001389	substrate-Mg2+ binding site; other site
1335916001390	catalytic residues [active]
1335916001391	aspartate-rich region 1; other site
1335916001392	active site lid residues [active]
1335916001393	aspartate-rich region 2; other site
1335916001394	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1335916001395	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1335916001396	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1335916001397	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1335916001398	Ligand Binding Site [chemical binding]; other site
1335916001399	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1335916001400	active site residue [active]
1335916001401	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
1335916001402	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1335916001403	conserved cys residue [active]
1335916001404	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1335916001405	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1335916001406	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916001407	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1335916001408	putative substrate translocation pore; other site
1335916001409	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1335916001410	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
1335916001411	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
1335916001412	UbiA prenyltransferase family; Region: UbiA; pfam01040
1335916001413	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
1335916001414	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1335916001415	Subunit I/III interface [polypeptide binding]; other site
1335916001416	Subunit III/IV interface [polypeptide binding]; other site
1335916001417	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1335916001418	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1335916001419	D-pathway; other site
1335916001420	Putative ubiquinol binding site [chemical binding]; other site
1335916001421	Low-spin heme (heme b) binding site [chemical binding]; other site
1335916001422	Putative water exit pathway; other site
1335916001423	Binuclear center (heme o3/CuB) [ion binding]; other site
1335916001424	K-pathway; other site
1335916001425	Putative proton exit pathway; other site
1335916001426	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1335916001427	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1335916001428	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1335916001429	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1335916001430	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916001431	putative substrate translocation pore; other site
1335916001432	hypothetical protein; Provisional; Region: PRK11627
1335916001433	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
1335916001434	transcriptional regulator BolA; Provisional; Region: PRK11628
1335916001435	trigger factor; Provisional; Region: tig; PRK01490
1335916001436	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1335916001437	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1335916001438	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1335916001439	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1335916001440	oligomer interface [polypeptide binding]; other site
1335916001441	active site residues [active]
1335916001442	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1335916001443	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1335916001444	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916001445	Walker A motif; other site
1335916001446	ATP binding site [chemical binding]; other site
1335916001447	Walker B motif; other site
1335916001448	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1335916001449	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1335916001450	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1335916001451	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1335916001452	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916001453	Walker A motif; other site
1335916001454	ATP binding site [chemical binding]; other site
1335916001455	Walker B motif; other site
1335916001456	arginine finger; other site
1335916001457	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1335916001458	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1335916001459	IHF dimer interface [polypeptide binding]; other site
1335916001460	IHF - DNA interface [nucleotide binding]; other site
1335916001461	periplasmic folding chaperone; Provisional; Region: PRK10788
1335916001462	SurA N-terminal domain; Region: SurA_N_3; cl07813
1335916001463	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1335916001464	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
1335916001465	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1335916001466	active site
1335916001467	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1335916001468	Ligand Binding Site [chemical binding]; other site
1335916001469	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1335916001470	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1335916001471	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1335916001472	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
1335916001473	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916001474	active site
1335916001475	motif I; other site
1335916001476	motif II; other site
1335916001477	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1335916001478	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1335916001479	putative DNA binding site [nucleotide binding]; other site
1335916001480	putative Zn2+ binding site [ion binding]; other site
1335916001481	AsnC family; Region: AsnC_trans_reg; pfam01037
1335916001482	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1335916001483	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1335916001484	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916001485	Walker A/P-loop; other site
1335916001486	ATP binding site [chemical binding]; other site
1335916001487	Q-loop/lid; other site
1335916001488	ABC transporter signature motif; other site
1335916001489	Walker B; other site
1335916001490	D-loop; other site
1335916001491	H-loop/switch region; other site
1335916001492	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
1335916001493	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1335916001494	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1335916001495	Walker A/P-loop; other site
1335916001496	ATP binding site [chemical binding]; other site
1335916001497	Q-loop/lid; other site
1335916001498	ABC transporter signature motif; other site
1335916001499	Walker B; other site
1335916001500	D-loop; other site
1335916001501	H-loop/switch region; other site
1335916001502	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
1335916001503	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1335916001504	ammonium transporter; Provisional; Region: PRK10666
1335916001505	acyl-CoA thioesterase II; Provisional; Region: PRK10526
1335916001506	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1335916001507	active site
1335916001508	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1335916001509	catalytic triad [active]
1335916001510	dimer interface [polypeptide binding]; other site
1335916001511	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
1335916001512	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1335916001513	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1335916001514	DNA binding site [nucleotide binding]
1335916001515	active site
1335916001516	Uncharacterized conserved protein [Function unknown]; Region: COG5507
1335916001517	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
1335916001518	maltose O-acetyltransferase; Provisional; Region: PRK10092
1335916001519	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1335916001520	active site
1335916001521	substrate binding site [chemical binding]; other site
1335916001522	trimer interface [polypeptide binding]; other site
1335916001523	CoA binding site [chemical binding]; other site
1335916001524	gene expression modulator; Provisional; Region: PRK10945
1335916001525	Biofilm formation regulator YbaJ; Region: YbaJ; pfam10757
1335916001526	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1335916001527	Protein export membrane protein; Region: SecD_SecF; cl14618
1335916001528	Protein export membrane protein; Region: SecD_SecF; cl14618
1335916001529	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1335916001530	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1335916001531	HlyD family secretion protein; Region: HlyD_3; pfam13437
1335916001532	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
1335916001533	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1335916001534	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1335916001535	hypothetical protein; Provisional; Region: PRK11281
1335916001536	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1335916001537	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
1335916001538	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1335916001539	hypothetical protein; Provisional; Region: PRK11038
1335916001540	primosomal replication protein N''; Provisional; Region: PRK10093
1335916001541	hypothetical protein; Provisional; Region: PRK10527
1335916001542	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1335916001543	active site
1335916001544	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
1335916001545	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916001546	Walker A motif; other site
1335916001547	ATP binding site [chemical binding]; other site
1335916001548	Walker B motif; other site
1335916001549	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1335916001550	arginine finger; other site
1335916001551	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1335916001552	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
1335916001553	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
1335916001554	hypothetical protein; Validated; Region: PRK00153
1335916001555	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
1335916001556	RecR protein; Region: RecR; pfam02132
1335916001557	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1335916001558	putative active site [active]
1335916001559	putative metal-binding site [ion binding]; other site
1335916001560	tetramer interface [polypeptide binding]; other site
1335916001561	heat shock protein 90; Provisional; Region: PRK05218
1335916001562	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916001563	ATP binding site [chemical binding]; other site
1335916001564	Mg2+ binding site [ion binding]; other site
1335916001565	G-X-G motif; other site
1335916001566	adenylate kinase; Reviewed; Region: adk; PRK00279
1335916001567	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1335916001568	AMP-binding site [chemical binding]; other site
1335916001569	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1335916001570	ferrochelatase; Region: hemH; TIGR00109
1335916001571	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1335916001572	C-terminal domain interface [polypeptide binding]; other site
1335916001573	active site
1335916001574	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1335916001575	active site
1335916001576	N-terminal domain interface [polypeptide binding]; other site
1335916001577	acetyl esterase; Provisional; Region: PRK10162
1335916001578	inosine/guanosine kinase; Provisional; Region: PRK15074
1335916001579	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1335916001580	putative cation:proton antiport protein; Provisional; Region: PRK10669
1335916001581	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
1335916001582	TrkA-N domain; Region: TrkA_N; pfam02254
1335916001583	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916001584	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1335916001585	putative substrate translocation pore; other site
1335916001586	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1335916001587	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
1335916001588	active site
1335916001589	metal binding site [ion binding]; metal-binding site
1335916001590	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1335916001591	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1335916001592	putative deacylase active site [active]
1335916001593	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
1335916001594	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
1335916001595	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1335916001596	non-specific DNA binding site [nucleotide binding]; other site
1335916001597	salt bridge; other site
1335916001598	sequence-specific DNA binding site [nucleotide binding]; other site
1335916001599	copper exporting ATPase; Provisional; Region: copA; PRK10671
1335916001600	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1335916001601	metal-binding site [ion binding]
1335916001602	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1335916001603	metal-binding site [ion binding]
1335916001604	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1335916001605	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916001606	motif II; other site
1335916001607	glutaminase; Reviewed; Region: PRK12356
1335916001608	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1335916001609	amino acid transporter; Region: 2A0306; TIGR00909
1335916001610	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
1335916001611	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1335916001612	DNA binding residues [nucleotide binding]
1335916001613	dimer interface [polypeptide binding]; other site
1335916001614	copper binding site [ion binding]; other site
1335916001615	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1335916001616	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1335916001617	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1335916001618	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
1335916001619	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916001620	Walker A/P-loop; other site
1335916001621	ATP binding site [chemical binding]; other site
1335916001622	Q-loop/lid; other site
1335916001623	ABC transporter signature motif; other site
1335916001624	Walker B; other site
1335916001625	D-loop; other site
1335916001626	H-loop/switch region; other site
1335916001627	Uncharacterized protein family (UPF0014); Region: UPF0014; pfam03649
1335916001628	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
1335916001629	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
1335916001630	oxidoreductase; Provisional; Region: PRK08017
1335916001631	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1335916001632	NADP binding site [chemical binding]; other site
1335916001633	active site
1335916001634	steroid binding site; other site
1335916001635	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1335916001636	active site
1335916001637	catalytic triad [active]
1335916001638	oxyanion hole [active]
1335916001639	switch loop; other site
1335916001640	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
1335916001641	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1335916001642	Walker A/P-loop; other site
1335916001643	ATP binding site [chemical binding]; other site
1335916001644	Q-loop/lid; other site
1335916001645	ABC transporter signature motif; other site
1335916001646	Walker B; other site
1335916001647	D-loop; other site
1335916001648	H-loop/switch region; other site
1335916001649	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
1335916001650	FtsX-like permease family; Region: FtsX; pfam02687
1335916001651	FtsX-like permease family; Region: FtsX; pfam02687
1335916001652	PAAR motif; Region: PAAR_motif; cl15808
1335916001653	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1335916001654	RHS Repeat; Region: RHS_repeat; pfam05593
1335916001655	RHS Repeat; Region: RHS_repeat; pfam05593
1335916001656	RHS Repeat; Region: RHS_repeat; pfam05593
1335916001657	RHS Repeat; Region: RHS_repeat; pfam05593
1335916001658	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1335916001659	RHS Repeat; Region: RHS_repeat; pfam05593
1335916001660	RHS Repeat; Region: RHS_repeat; pfam05593
1335916001661	RHS protein; Region: RHS; pfam03527
1335916001662	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1335916001663	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
1335916001664	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1335916001665	RHS protein; Region: RHS; pfam03527
1335916001666	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1335916001667	hypothetical protein; Provisional; Region: PRK14710
1335916001668	Winged helix-turn helix; Region: HTH_29; pfam13551
1335916001669	Helix-turn-helix domain; Region: HTH_28; pfam13518
1335916001670	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
1335916001671	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
1335916001672	active site residue [active]
1335916001673	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
1335916001674	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916001675	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1335916001676	dimerization interface [polypeptide binding]; other site
1335916001677	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
1335916001678	ureidoglycolate hydrolase; Provisional; Region: PRK03606
1335916001679	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
1335916001680	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1335916001681	Bacterial transcriptional regulator; Region: IclR; pfam01614
1335916001682	glyoxylate carboligase; Provisional; Region: PRK11269
1335916001683	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1335916001684	PYR/PP interface [polypeptide binding]; other site
1335916001685	dimer interface [polypeptide binding]; other site
1335916001686	TPP binding site [chemical binding]; other site
1335916001687	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1335916001688	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
1335916001689	TPP-binding site [chemical binding]; other site
1335916001690	hydroxypyruvate isomerase; Provisional; Region: PRK09997
1335916001691	tartronate semialdehyde reductase; Provisional; Region: PRK15059
1335916001692	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1335916001693	nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; Region: SLC-NCS1sbd; cd10323
1335916001694	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1335916001695	Na binding site [ion binding]; other site
1335916001696	substrate binding site [chemical binding]; other site
1335916001697	allantoinase; Provisional; Region: PRK08044
1335916001698	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
1335916001699	active site
1335916001700	putative uracil/xanthine transporter; Provisional; Region: PRK11412
1335916001701	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
1335916001702	Protein of unknown function (DUF861); Region: Cupin_3; pfam05899
1335916001703	Cupin domain; Region: Cupin_2; cl17218
1335916001704	allantoate amidohydrolase; Region: AllC; TIGR03176
1335916001705	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1335916001706	active site
1335916001707	metal binding site [ion binding]; metal-binding site
1335916001708	dimer interface [polypeptide binding]; other site
1335916001709	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
1335916001710	membrane protein FdrA; Validated; Region: PRK06091
1335916001711	CoA binding domain; Region: CoA_binding; pfam02629
1335916001712	CoA-ligase; Region: Ligase_CoA; pfam00549
1335916001713	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
1335916001714	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
1335916001715	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1335916001716	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1335916001717	putative substrate binding site [chemical binding]; other site
1335916001718	nucleotide binding site [chemical binding]; other site
1335916001719	nucleotide binding site [chemical binding]; other site
1335916001720	homodimer interface [polypeptide binding]; other site
1335916001721	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1335916001722	ATP-grasp domain; Region: ATP-grasp; pfam02222
1335916001723	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1335916001724	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1335916001725	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1335916001726	putative active site [active]
1335916001727	putative metal binding site [ion binding]; other site
1335916001728	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1335916001729	substrate binding site [chemical binding]; other site
1335916001730	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1335916001731	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1335916001732	active site
1335916001733	HIGH motif; other site
1335916001734	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1335916001735	KMSKS motif; other site
1335916001736	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1335916001737	tRNA binding surface [nucleotide binding]; other site
1335916001738	anticodon binding site; other site
1335916001739	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
1335916001740	ribosome-associated protein; Provisional; Region: PRK11507
1335916001741	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1335916001742	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1335916001743	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1335916001744	homodimer interface [polypeptide binding]; other site
1335916001745	NADP binding site [chemical binding]; other site
1335916001746	substrate binding site [chemical binding]; other site
1335916001747	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
1335916001748	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1335916001749	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1335916001750	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1335916001751	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
1335916001752	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
1335916001753	transcriptional regulator FimZ; Provisional; Region: PRK09935
1335916001754	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916001755	active site
1335916001756	phosphorylation site [posttranslational modification]
1335916001757	intermolecular recognition site; other site
1335916001758	dimerization interface [polypeptide binding]; other site
1335916001759	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916001760	DNA binding residues [nucleotide binding]
1335916001761	dimerization interface [polypeptide binding]; other site
1335916001762	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1335916001763	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916001764	hypothetical protein; Provisional; Region: PRK09936
1335916001765	bacteriophage N4 adsorption protein B; Provisional; Region: nfrB; PRK11234
1335916001766	active site
1335916001767	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
1335916001768	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
1335916001769	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1335916001770	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916001771	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1335916001772	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1335916001773	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1335916001774	RHS Repeat; Region: RHS_repeat; cl11982
1335916001775	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1335916001776	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1335916001777	RHS Repeat; Region: RHS_repeat; cl11982
1335916001778	RHS Repeat; Region: RHS_repeat; cl11982
1335916001779	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1335916001780	PAAR motif; Region: PAAR_motif; pfam05488
1335916001781	RHS Repeat; Region: RHS_repeat; cl11982
1335916001782	RHS Repeat; Region: RHS_repeat; pfam05593
1335916001783	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1335916001784	RHS Repeat; Region: RHS_repeat; pfam05593
1335916001785	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1335916001786	RHS Repeat; Region: RHS_repeat; pfam05593
1335916001787	RHS Repeat; Region: RHS_repeat; cl11982
1335916001788	RHS Repeat; Region: RHS_repeat; pfam05593
1335916001789	RHS Repeat; Region: RHS_repeat; cl11982
1335916001790	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1335916001791	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1335916001792	Uncharacterized conserved protein [Function unknown]; Region: COG5435
1335916001793	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1335916001794	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1335916001795	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1335916001796	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1335916001797	sensor kinase CusS; Provisional; Region: PRK09835
1335916001798	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1335916001799	dimerization interface [polypeptide binding]; other site
1335916001800	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916001801	dimer interface [polypeptide binding]; other site
1335916001802	phosphorylation site [posttranslational modification]
1335916001803	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916001804	ATP binding site [chemical binding]; other site
1335916001805	Mg2+ binding site [ion binding]; other site
1335916001806	G-X-G motif; other site
1335916001807	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
1335916001808	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916001809	active site
1335916001810	phosphorylation site [posttranslational modification]
1335916001811	intermolecular recognition site; other site
1335916001812	dimerization interface [polypeptide binding]; other site
1335916001813	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1335916001814	DNA binding site [nucleotide binding]
1335916001815	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
1335916001816	periplasmic copper-binding protein; Provisional; Region: PRK09838
1335916001817	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
1335916001818	HlyD family secretion protein; Region: HlyD_3; pfam13437
1335916001819	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
1335916001820	phenylalanine transporter; Provisional; Region: PRK10249
1335916001821	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1335916001822	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1335916001823	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1335916001824	dimer interface [polypeptide binding]; other site
1335916001825	FMN binding site [chemical binding]; other site
1335916001826	hypothetical protein; Provisional; Region: PRK10250
1335916001827	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
1335916001828	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
1335916001829	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
1335916001830	Hok/gef family; Region: HOK_GEF; pfam01848
1335916001831	Hok/gef family; Region: HOK_GEF; pfam01848
1335916001832	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
1335916001833	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1335916001834	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
1335916001835	outer membrane receptor FepA; Provisional; Region: PRK13524
1335916001836	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1335916001837	N-terminal plug; other site
1335916001838	ligand-binding site [chemical binding]; other site
1335916001839	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
1335916001840	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1335916001841	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1335916001842	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
1335916001843	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
1335916001844	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1335916001845	acyl-activating enzyme (AAE) consensus motif; other site
1335916001846	AMP binding site [chemical binding]; other site
1335916001847	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1335916001848	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
1335916001849	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1335916001850	Walker A/P-loop; other site
1335916001851	ATP binding site [chemical binding]; other site
1335916001852	Q-loop/lid; other site
1335916001853	ABC transporter signature motif; other site
1335916001854	Walker B; other site
1335916001855	D-loop; other site
1335916001856	H-loop/switch region; other site
1335916001857	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1335916001858	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1335916001859	ABC-ATPase subunit  interface; other site
1335916001860	dimer interface [polypeptide binding]; other site
1335916001861	putative PBP binding regions; other site
1335916001862	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1335916001863	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1335916001864	ABC-ATPase subunit  interface; other site
1335916001865	dimer interface [polypeptide binding]; other site
1335916001866	putative PBP binding regions; other site
1335916001867	enterobactin exporter EntS; Provisional; Region: PRK10489
1335916001868	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916001869	putative substrate translocation pore; other site
1335916001870	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
1335916001871	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1335916001872	siderophore binding site; other site
1335916001873	isochorismate synthase EntC; Provisional; Region: PRK15016
1335916001874	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1335916001875	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
1335916001876	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
1335916001877	acyl-activating enzyme (AAE) consensus motif; other site
1335916001878	active site
1335916001879	AMP binding site [chemical binding]; other site
1335916001880	substrate binding site [chemical binding]; other site
1335916001881	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
1335916001882	hydrophobic substrate binding pocket; other site
1335916001883	Isochorismatase family; Region: Isochorismatase; pfam00857
1335916001884	active site
1335916001885	conserved cis-peptide bond; other site
1335916001886	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
1335916001887	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
1335916001888	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
1335916001889	putative NAD(P) binding site [chemical binding]; other site
1335916001890	active site
1335916001891	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1335916001892	CoenzymeA binding site [chemical binding]; other site
1335916001893	subunit interaction site [polypeptide binding]; other site
1335916001894	PHB binding site; other site
1335916001895	carbon starvation protein A; Provisional; Region: PRK15015
1335916001896	Carbon starvation protein CstA; Region: CstA; pfam02554
1335916001897	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1335916001898	Uncharacterized small protein [Function unknown]; Region: COG2879
1335916001899	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1335916001900	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
1335916001901	putative active site [active]
1335916001902	metal binding site [ion binding]; metal-binding site
1335916001903	methionine aminotransferase; Validated; Region: PRK09082
1335916001904	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1335916001905	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916001906	homodimer interface [polypeptide binding]; other site
1335916001907	catalytic residue [active]
1335916001908	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1335916001909	ParB-like nuclease domain; Region: ParBc; pfam02195
1335916001910	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
1335916001911	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1335916001912	Active Sites [active]
1335916001913	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
1335916001914	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1335916001915	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916001916	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1335916001917	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
1335916001918	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1335916001919	dimerization domain [polypeptide binding]; other site
1335916001920	dimer interface [polypeptide binding]; other site
1335916001921	catalytic residues [active]
1335916001922	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
1335916001923	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1335916001924	dimer interface [polypeptide binding]; other site
1335916001925	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1335916001926	catalytic triad [active]
1335916001927	peroxidatic and resolving cysteines [active]
1335916001928	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1335916001929	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1335916001930	catalytic residue [active]
1335916001931	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1335916001932	catalytic residues [active]
1335916001933	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1335916001934	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916001935	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1335916001936	Ligand Binding Site [chemical binding]; other site
1335916001937	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1335916001938	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1335916001939	NAD binding site [chemical binding]; other site
1335916001940	catalytic Zn binding site [ion binding]; other site
1335916001941	structural Zn binding site [ion binding]; other site
1335916001942	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
1335916001943	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1335916001944	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
1335916001945	B1 nucleotide binding pocket [chemical binding]; other site
1335916001946	B2 nucleotide binding pocket [chemical binding]; other site
1335916001947	CAS motifs; other site
1335916001948	active site
1335916001949	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1335916001950	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1335916001951	transmembrane helices; other site
1335916001952	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
1335916001953	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
1335916001954	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1335916001955	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1335916001956	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
1335916001957	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1335916001958	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1335916001959	putative active site [active]
1335916001960	(T/H)XGH motif; other site
1335916001961	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
1335916001962	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1335916001963	putative active site [active]
1335916001964	heme pocket [chemical binding]; other site
1335916001965	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916001966	ATP binding site [chemical binding]; other site
1335916001967	Mg2+ binding site [ion binding]; other site
1335916001968	G-X-G motif; other site
1335916001969	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
1335916001970	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916001971	active site
1335916001972	phosphorylation site [posttranslational modification]
1335916001973	intermolecular recognition site; other site
1335916001974	dimerization interface [polypeptide binding]; other site
1335916001975	Transcriptional regulator; Region: CitT; pfam12431
1335916001976	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
1335916001977	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1335916001978	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1335916001979	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1335916001980	DNA-binding site [nucleotide binding]; DNA binding site
1335916001981	RNA-binding motif; other site
1335916001982	chromosome condensation membrane protein; Provisional; Region: PRK14196
1335916001983	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1335916001984	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
1335916001985	putative active site [active]
1335916001986	catalytic triad [active]
1335916001987	putative dimer interface [polypeptide binding]; other site
1335916001988	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
1335916001989	lipoyl synthase; Provisional; Region: PRK05481
1335916001990	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916001991	FeS/SAM binding site; other site
1335916001992	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1335916001993	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916001994	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1335916001995	substrate binding pocket [chemical binding]; other site
1335916001996	dimerization interface [polypeptide binding]; other site
1335916001997	lipoate-protein ligase B; Provisional; Region: PRK14342
1335916001998	hypothetical protein; Provisional; Region: PRK04998
1335916001999	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1335916002000	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1335916002001	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1335916002002	rare lipoprotein A; Provisional; Region: PRK10672
1335916002003	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1335916002004	Sporulation related domain; Region: SPOR; pfam05036
1335916002005	cell wall shape-determining protein; Provisional; Region: PRK10794
1335916002006	penicillin-binding protein 2; Provisional; Region: PRK10795
1335916002007	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1335916002008	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1335916002009	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
1335916002010	ribosome-associated protein; Provisional; Region: PRK11538
1335916002011	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1335916002012	catalytic core [active]
1335916002013	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1335916002014	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1335916002015	active site
1335916002016	(T/H)XGH motif; other site
1335916002017	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1335916002018	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1335916002019	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
1335916002020	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1335916002021	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1335916002022	HIGH motif; other site
1335916002023	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1335916002024	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1335916002025	active site
1335916002026	KMSKS motif; other site
1335916002027	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1335916002028	tRNA binding surface [nucleotide binding]; other site
1335916002029	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1335916002030	hypothetical protein; Provisional; Region: PRK11032
1335916002031	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
1335916002032	Sel1-like repeats; Region: SEL1; smart00671
1335916002033	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1335916002034	Sel1-like repeats; Region: SEL1; smart00671
1335916002035	Sel1-like repeats; Region: SEL1; smart00671
1335916002036	Sel1-like repeats; Region: SEL1; smart00671
1335916002037	Sel1-like repeats; Region: SEL1; smart00671
1335916002038	Sel1-like repeats; Region: SEL1; smart00671
1335916002039	Sel1-like repeats; Region: SEL1; smart00671
1335916002040	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1335916002041	DnaJ molecular chaperone homology domain; Region: DnaJ; smart00271
1335916002042	HSP70 interaction site [polypeptide binding]; other site
1335916002043	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1335916002044	Sel1-like repeats; Region: SEL1; smart00671
1335916002045	Sel1-like repeats; Region: SEL1; smart00671
1335916002046	Sel1-like repeats; Region: SEL1; smart00671
1335916002047	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1335916002048	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
1335916002049	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
1335916002050	nucleotide binding site [chemical binding]; other site
1335916002051	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1335916002052	SBD interface [polypeptide binding]; other site
1335916002053	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1335916002054	active site
1335916002055	tetramer interface [polypeptide binding]; other site
1335916002056	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1335916002057	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1335916002058	Walker A/P-loop; other site
1335916002059	ATP binding site [chemical binding]; other site
1335916002060	Q-loop/lid; other site
1335916002061	ABC transporter signature motif; other site
1335916002062	Walker B; other site
1335916002063	D-loop; other site
1335916002064	H-loop/switch region; other site
1335916002065	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1335916002066	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916002067	dimer interface [polypeptide binding]; other site
1335916002068	conserved gate region; other site
1335916002069	putative PBP binding loops; other site
1335916002070	ABC-ATPase subunit interface; other site
1335916002071	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1335916002072	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916002073	dimer interface [polypeptide binding]; other site
1335916002074	conserved gate region; other site
1335916002075	putative PBP binding loops; other site
1335916002076	ABC-ATPase subunit interface; other site
1335916002077	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1335916002078	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916002079	substrate binding pocket [chemical binding]; other site
1335916002080	membrane-bound complex binding site; other site
1335916002081	hinge residues; other site
1335916002082	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1335916002083	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1335916002084	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1335916002085	putative active site [active]
1335916002086	catalytic triad [active]
1335916002087	putative dimer interface [polypeptide binding]; other site
1335916002088	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
1335916002089	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1335916002090	Transporter associated domain; Region: CorC_HlyC; smart01091
1335916002091	metal-binding heat shock protein; Provisional; Region: PRK00016
1335916002092	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1335916002093	PhoH-like protein; Region: PhoH; pfam02562
1335916002094	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1335916002095	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1335916002096	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916002097	FeS/SAM binding site; other site
1335916002098	TRAM domain; Region: TRAM; pfam01938
1335916002099	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
1335916002100	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1335916002101	asparagine synthetase B; Provisional; Region: asnB; PRK09431
1335916002102	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1335916002103	active site
1335916002104	dimer interface [polypeptide binding]; other site
1335916002105	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1335916002106	Ligand Binding Site [chemical binding]; other site
1335916002107	Molecular Tunnel; other site
1335916002108	UMP phosphatase; Provisional; Region: PRK10444
1335916002109	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916002110	active site
1335916002111	motif I; other site
1335916002112	motif II; other site
1335916002113	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916002114	MarR family; Region: MarR; pfam01047
1335916002115	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1335916002116	ROK family; Region: ROK; pfam00480
1335916002117	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
1335916002118	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1335916002119	active site
1335916002120	dimer interface [polypeptide binding]; other site
1335916002121	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1335916002122	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1335916002123	active site
1335916002124	trimer interface [polypeptide binding]; other site
1335916002125	allosteric site; other site
1335916002126	active site lid [active]
1335916002127	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1335916002128	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
1335916002129	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1335916002130	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1335916002131	active site turn [active]
1335916002132	phosphorylation site [posttranslational modification]
1335916002133	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1335916002134	HPr interaction site; other site
1335916002135	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1335916002136	active site
1335916002137	phosphorylation site [posttranslational modification]
1335916002138	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1335916002139	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1335916002140	active site
1335916002141	HIGH motif; other site
1335916002142	nucleotide binding site [chemical binding]; other site
1335916002143	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1335916002144	KMSKS motif; other site
1335916002145	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1335916002146	outer membrane porin, OprD family; Region: OprD; pfam03573
1335916002147	YbfN-like lipoprotein; Region: YbfN; pfam13982
1335916002148	ferric uptake regulator; Provisional; Region: fur; PRK09462
1335916002149	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1335916002150	metal binding site 2 [ion binding]; metal-binding site
1335916002151	putative DNA binding helix; other site
1335916002152	metal binding site 1 [ion binding]; metal-binding site
1335916002153	dimer interface [polypeptide binding]; other site
1335916002154	structural Zn2+ binding site [ion binding]; other site
1335916002155	flavodoxin FldA; Validated; Region: PRK09267
1335916002156	LexA regulated protein; Provisional; Region: PRK11675
1335916002157	acyl-CoA esterase; Provisional; Region: PRK10673
1335916002158	PGAP1-like protein; Region: PGAP1; pfam07819
1335916002159	replication initiation regulator SeqA; Provisional; Region: PRK11187
1335916002160	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
1335916002161	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1335916002162	active site
1335916002163	substrate binding site [chemical binding]; other site
1335916002164	metal binding site [ion binding]; metal-binding site
1335916002165	putrescine transporter; Provisional; Region: potE; PRK10655
1335916002166	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1335916002167	ornithine decarboxylase; Provisional; Region: PRK13578
1335916002168	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1335916002169	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1335916002170	homodimer interface [polypeptide binding]; other site
1335916002171	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916002172	catalytic residue [active]
1335916002173	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1335916002174	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
1335916002175	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916002176	active site
1335916002177	phosphorylation site [posttranslational modification]
1335916002178	intermolecular recognition site; other site
1335916002179	dimerization interface [polypeptide binding]; other site
1335916002180	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1335916002181	DNA binding site [nucleotide binding]
1335916002182	sensor protein KdpD; Provisional; Region: PRK10490
1335916002183	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1335916002184	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1335916002185	Ligand Binding Site [chemical binding]; other site
1335916002186	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1335916002187	GAF domain; Region: GAF_3; pfam13492
1335916002188	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916002189	dimer interface [polypeptide binding]; other site
1335916002190	phosphorylation site [posttranslational modification]
1335916002191	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916002192	ATP binding site [chemical binding]; other site
1335916002193	Mg2+ binding site [ion binding]; other site
1335916002194	G-X-G motif; other site
1335916002195	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
1335916002196	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1335916002197	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1335916002198	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1335916002199	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
1335916002200	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1335916002201	hypothetical protein; Provisional; Region: PRK10167
1335916002202	Uncharacterized conserved protein [Function unknown]; Region: COG3272
1335916002203	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1335916002204	DNA photolyase; Region: DNA_photolyase; pfam00875
1335916002205	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1335916002206	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916002207	putative substrate translocation pore; other site
1335916002208	POT family; Region: PTR2; pfam00854
1335916002209	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1335916002210	metal-binding protein; Provisional; Region: PRK10799
1335916002211	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1335916002212	sensor histidine kinase inhibitor, KipI family; Region: TIGR00370
1335916002213	biotin-dependent carboxylase uncharacterized domain; Region: urea_amlyse_rel; TIGR00724
1335916002214	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
1335916002215	putative active site [active]
1335916002216	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
1335916002217	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1335916002218	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1335916002219	Fimbrial protein; Region: Fimbrial; pfam00419
1335916002220	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1335916002221	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1335916002222	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1335916002223	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1335916002224	PapC N-terminal domain; Region: PapC_N; pfam13954
1335916002225	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1335916002226	PapC C-terminal domain; Region: PapC_C; pfam13953
1335916002227	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1335916002228	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1335916002229	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1335916002230	dimer interface [polypeptide binding]; other site
1335916002231	active site
1335916002232	citrylCoA binding site [chemical binding]; other site
1335916002233	NADH binding [chemical binding]; other site
1335916002234	cationic pore residues; other site
1335916002235	oxalacetate/citrate binding site [chemical binding]; other site
1335916002236	coenzyme A binding site [chemical binding]; other site
1335916002237	catalytic triad [active]
1335916002238	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1335916002239	Iron-sulfur protein interface; other site
1335916002240	proximal quinone binding site [chemical binding]; other site
1335916002241	SdhD (CybS) interface [polypeptide binding]; other site
1335916002242	proximal heme binding site [chemical binding]; other site
1335916002243	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
1335916002244	SdhC subunit interface [polypeptide binding]; other site
1335916002245	proximal heme binding site [chemical binding]; other site
1335916002246	cardiolipin binding site; other site
1335916002247	Iron-sulfur protein interface; other site
1335916002248	proximal quinone binding site [chemical binding]; other site
1335916002249	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
1335916002250	L-aspartate oxidase; Provisional; Region: PRK06175
1335916002251	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1335916002252	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1335916002253	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1335916002254	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1335916002255	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1335916002256	TPP-binding site [chemical binding]; other site
1335916002257	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1335916002258	dimer interface [polypeptide binding]; other site
1335916002259	PYR/PP interface [polypeptide binding]; other site
1335916002260	TPP binding site [chemical binding]; other site
1335916002261	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1335916002262	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1335916002263	E3 interaction surface; other site
1335916002264	lipoyl attachment site [posttranslational modification]; other site
1335916002265	e3 binding domain; Region: E3_binding; pfam02817
1335916002266	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1335916002267	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1335916002268	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1335916002269	CoA-ligase; Region: Ligase_CoA; pfam00549
1335916002270	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1335916002271	CoA binding domain; Region: CoA_binding; smart00881
1335916002272	CoA-ligase; Region: Ligase_CoA; pfam00549
1335916002273	DNA-binding transcriptional repressor MngR; Provisional; Region: PRK09764
1335916002274	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916002275	DNA-binding site [nucleotide binding]; DNA binding site
1335916002276	UTRA domain; Region: UTRA; pfam07702
1335916002277	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
1335916002278	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1335916002279	active site
1335916002280	phosphorylation site [posttranslational modification]
1335916002281	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1335916002282	active site
1335916002283	P-loop; other site
1335916002284	phosphorylation site [posttranslational modification]
1335916002285	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1335916002286	alpha-mannosidase; Provisional; Region: PRK09819
1335916002287	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
1335916002288	active site
1335916002289	metal binding site [ion binding]; metal-binding site
1335916002290	catalytic site [active]
1335916002291	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
1335916002292	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1335916002293	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
1335916002294	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
1335916002295	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1335916002296	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
1335916002297	hypothetical protein; Provisional; Region: PRK10588
1335916002298	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1335916002299	active site
1335916002300	colicin uptake protein TolQ; Provisional; Region: PRK10801
1335916002301	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1335916002302	colicin uptake protein TolR; Provisional; Region: PRK11024
1335916002303	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
1335916002304	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
1335916002305	TolA C-terminal; Region: TolA; pfam06519
1335916002306	translocation protein TolB; Provisional; Region: tolB; PRK03629
1335916002307	TolB amino-terminal domain; Region: TolB_N; pfam04052
1335916002308	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1335916002309	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1335916002310	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1335916002311	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1335916002312	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1335916002313	ligand binding site [chemical binding]; other site
1335916002314	tol-pal system protein YbgF; Provisional; Region: PRK10803
1335916002315	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1335916002316	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1335916002317	quinolinate synthetase; Provisional; Region: PRK09375
1335916002318	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1335916002319	zinc transporter ZitB; Provisional; Region: PRK03557
1335916002320	YbgS-like protein; Region: YbgS; pfam13985
1335916002321	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1335916002322	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1335916002323	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1335916002324	catalytic core [active]
1335916002325	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1335916002326	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1335916002327	active site
1335916002328	catalytic residues [active]
1335916002329	galactokinase; Provisional; Region: PRK05101
1335916002330	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1335916002331	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1335916002332	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1335916002333	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1335916002334	dimer interface [polypeptide binding]; other site
1335916002335	active site
1335916002336	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
1335916002337	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1335916002338	NAD binding site [chemical binding]; other site
1335916002339	homodimer interface [polypeptide binding]; other site
1335916002340	active site
1335916002341	substrate binding site [chemical binding]; other site
1335916002342	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
1335916002343	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1335916002344	Walker A/P-loop; other site
1335916002345	ATP binding site [chemical binding]; other site
1335916002346	Q-loop/lid; other site
1335916002347	ABC transporter signature motif; other site
1335916002348	Walker B; other site
1335916002349	D-loop; other site
1335916002350	H-loop/switch region; other site
1335916002351	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916002352	Walker A/P-loop; other site
1335916002353	ATP binding site [chemical binding]; other site
1335916002354	Q-loop/lid; other site
1335916002355	ABC transporter signature motif; other site
1335916002356	Walker B; other site
1335916002357	D-loop; other site
1335916002358	H-loop/switch region; other site
1335916002359	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
1335916002360	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1335916002361	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1335916002362	TOBE domain; Region: TOBE; pfam03459
1335916002363	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
1335916002364	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
1335916002365	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916002366	substrate binding pocket [chemical binding]; other site
1335916002367	membrane-bound complex binding site; other site
1335916002368	hinge residues; other site
1335916002369	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1335916002370	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916002371	putative PBP binding loops; other site
1335916002372	ABC-ATPase subunit interface; other site
1335916002373	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1335916002374	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916002375	Walker A/P-loop; other site
1335916002376	ATP binding site [chemical binding]; other site
1335916002377	Q-loop/lid; other site
1335916002378	ABC transporter signature motif; other site
1335916002379	Walker B; other site
1335916002380	D-loop; other site
1335916002381	H-loop/switch region; other site
1335916002382	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1335916002383	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1335916002384	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916002385	motif II; other site
1335916002386	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916002387	6-phosphogluconolactonase; Provisional; Region: PRK11028
1335916002388	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1335916002389	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916002390	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1335916002391	putative dimerization interface [polypeptide binding]; other site
1335916002392	PrpF protein; Region: PrpF; pfam04303
1335916002393	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1335916002394	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1335916002395	transmembrane helices; other site
1335916002396	putative hydratase; Provisional; Region: PRK11413
1335916002397	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
1335916002398	substrate binding site [chemical binding]; other site
1335916002399	ligand binding site [chemical binding]; other site
1335916002400	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
1335916002401	substrate binding site [chemical binding]; other site
1335916002402	acyl-CoA thioesterase; Provisional; Region: PRK10531
1335916002403	putative pectinesterase; Region: PLN02432; cl01911
1335916002404	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1335916002405	substrate binding site [chemical binding]; other site
1335916002406	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
1335916002407	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1335916002408	inhibitor-cofactor binding pocket; inhibition site
1335916002409	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916002410	catalytic residue [active]
1335916002411	biotin synthase; Provisional; Region: PRK15108
1335916002412	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916002413	FeS/SAM binding site; other site
1335916002414	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1335916002415	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1335916002416	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1335916002417	substrate-cofactor binding pocket; other site
1335916002418	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916002419	catalytic residue [active]
1335916002420	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1335916002421	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916002422	S-adenosylmethionine binding site [chemical binding]; other site
1335916002423	AAA domain; Region: AAA_26; pfam13500
1335916002424	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1335916002425	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
1335916002426	ADP binding site [chemical binding]; other site
1335916002427	excinuclease ABC subunit B; Provisional; Region: PRK05298
1335916002428	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1335916002429	ATP binding site [chemical binding]; other site
1335916002430	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1335916002431	nucleotide binding region [chemical binding]; other site
1335916002432	ATP-binding site [chemical binding]; other site
1335916002433	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1335916002434	UvrB/uvrC motif; Region: UVR; pfam02151
1335916002435	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1335916002436	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1335916002437	putative substrate binding pocket [chemical binding]; other site
1335916002438	dimer interface [polypeptide binding]; other site
1335916002439	phosphate binding site [ion binding]; other site
1335916002440	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1335916002441	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916002442	FeS/SAM binding site; other site
1335916002443	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1335916002444	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1335916002445	MPT binding site; other site
1335916002446	trimer interface [polypeptide binding]; other site
1335916002447	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1335916002448	trimer interface [polypeptide binding]; other site
1335916002449	dimer interface [polypeptide binding]; other site
1335916002450	putative active site [active]
1335916002451	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1335916002452	MoaE interaction surface [polypeptide binding]; other site
1335916002453	MoeB interaction surface [polypeptide binding]; other site
1335916002454	thiocarboxylated glycine; other site
1335916002455	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1335916002456	MoaE homodimer interface [polypeptide binding]; other site
1335916002457	MoaD interaction [polypeptide binding]; other site
1335916002458	active site residues [active]
1335916002459	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1335916002460	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1335916002461	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1335916002462	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1335916002463	Predicted integral membrane protein [Function unknown]; Region: COG0392
1335916002464	cardiolipin synthase 2; Provisional; Region: PRK11263
1335916002465	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1335916002466	putative active site [active]
1335916002467	catalytic site [active]
1335916002468	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
1335916002469	putative active site [active]
1335916002470	catalytic site [active]
1335916002471	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
1335916002472	putative catalytic site [active]
1335916002473	putative metal binding site [ion binding]; other site
1335916002474	putative phosphate binding site [ion binding]; other site
1335916002475	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
1335916002476	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1335916002477	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1335916002478	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1335916002479	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1335916002480	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1335916002481	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1335916002482	Walker A/P-loop; other site
1335916002483	ATP binding site [chemical binding]; other site
1335916002484	Q-loop/lid; other site
1335916002485	ABC transporter signature motif; other site
1335916002486	Walker B; other site
1335916002487	D-loop; other site
1335916002488	H-loop/switch region; other site
1335916002489	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1335916002490	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1335916002491	Walker A/P-loop; other site
1335916002492	ATP binding site [chemical binding]; other site
1335916002493	Q-loop/lid; other site
1335916002494	ABC transporter signature motif; other site
1335916002495	Walker B; other site
1335916002496	D-loop; other site
1335916002497	H-loop/switch region; other site
1335916002498	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1335916002499	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1335916002500	HlyD family secretion protein; Region: HlyD_3; pfam13437
1335916002501	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
1335916002502	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1335916002503	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
1335916002504	helicase 45; Provisional; Region: PTZ00424
1335916002505	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1335916002506	ATP binding site [chemical binding]; other site
1335916002507	Mg++ binding site [ion binding]; other site
1335916002508	motif III; other site
1335916002509	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1335916002510	nucleotide binding region [chemical binding]; other site
1335916002511	ATP-binding site [chemical binding]; other site
1335916002512	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3236
1335916002513	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
1335916002514	DEAD_2; Region: DEAD_2; pfam06733
1335916002515	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1335916002516	glycosyl transferase family protein; Provisional; Region: PRK08136
1335916002517	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1335916002518	putative dehydrogenase; Provisional; Region: PRK10098
1335916002519	hypothetical protein; Provisional; Region: PRK10259
1335916002520	hypothetical protein; Provisional; Region: PRK11019
1335916002521	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
1335916002522	catecholate siderophore receptor Fiu; Provisional; Region: PRK09840
1335916002523	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1335916002524	N-terminal plug; other site
1335916002525	ligand-binding site [chemical binding]; other site
1335916002526	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1335916002527	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
1335916002528	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
1335916002529	putative mechanosensitive channel protein; Provisional; Region: PRK11465
1335916002530	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1335916002531	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
1335916002532	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1335916002533	Walker A/P-loop; other site
1335916002534	ATP binding site [chemical binding]; other site
1335916002535	Q-loop/lid; other site
1335916002536	ABC transporter signature motif; other site
1335916002537	Walker B; other site
1335916002538	D-loop; other site
1335916002539	H-loop/switch region; other site
1335916002540	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1335916002541	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916002542	dimer interface [polypeptide binding]; other site
1335916002543	conserved gate region; other site
1335916002544	putative PBP binding loops; other site
1335916002545	ABC-ATPase subunit interface; other site
1335916002546	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
1335916002547	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916002548	substrate binding pocket [chemical binding]; other site
1335916002549	membrane-bound complex binding site; other site
1335916002550	hinge residues; other site
1335916002551	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1335916002552	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1335916002553	dimerization interface [polypeptide binding]; other site
1335916002554	DPS ferroxidase diiron center [ion binding]; other site
1335916002555	ion pore; other site
1335916002556	threonine and homoserine efflux system; Provisional; Region: PRK10532
1335916002557	EamA-like transporter family; Region: EamA; pfam00892
1335916002558	outer membrane protein X; Provisional; Region: ompX; PRK09408
1335916002559	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1335916002560	Sulfatase; Region: Sulfatase; pfam00884
1335916002561	manganese transport regulator MntR; Provisional; Region: PRK11050
1335916002562	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1335916002563	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1335916002564	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1335916002565	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
1335916002566	transmembrane helices; other site
1335916002567	L,D-transpeptidase; Provisional; Region: PRK10260
1335916002568	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1335916002569	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1335916002570	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916002571	Walker A/P-loop; other site
1335916002572	ATP binding site [chemical binding]; other site
1335916002573	Q-loop/lid; other site
1335916002574	ABC transporter signature motif; other site
1335916002575	Walker B; other site
1335916002576	D-loop; other site
1335916002577	H-loop/switch region; other site
1335916002578	ABC transporter; Region: ABC_tran_2; pfam12848
1335916002579	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1335916002580	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1335916002581	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1335916002582	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1335916002583	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
1335916002584	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1335916002585	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916002586	active site
1335916002587	motif I; other site
1335916002588	motif II; other site
1335916002589	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916002590	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
1335916002591	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1335916002592	dimer interface [polypeptide binding]; other site
1335916002593	active site
1335916002594	glycine loop; other site
1335916002595	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
1335916002596	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1335916002597	active site
1335916002598	intersubunit interactions; other site
1335916002599	catalytic residue [active]
1335916002600	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1335916002601	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1335916002602	ATP binding site [chemical binding]; other site
1335916002603	substrate interface [chemical binding]; other site
1335916002604	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1335916002605	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1335916002606	dimer interface [polypeptide binding]; other site
1335916002607	putative functional site; other site
1335916002608	putative MPT binding site; other site
1335916002609	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
1335916002610	catalytic nucleophile [active]
1335916002611	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
1335916002612	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1335916002613	Walker A/P-loop; other site
1335916002614	ATP binding site [chemical binding]; other site
1335916002615	Q-loop/lid; other site
1335916002616	ABC transporter signature motif; other site
1335916002617	Walker B; other site
1335916002618	D-loop; other site
1335916002619	H-loop/switch region; other site
1335916002620	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1335916002621	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1335916002622	Walker A/P-loop; other site
1335916002623	ATP binding site [chemical binding]; other site
1335916002624	Q-loop/lid; other site
1335916002625	ABC transporter signature motif; other site
1335916002626	Walker B; other site
1335916002627	D-loop; other site
1335916002628	H-loop/switch region; other site
1335916002629	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1335916002630	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
1335916002631	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
1335916002632	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
1335916002633	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916002634	dimer interface [polypeptide binding]; other site
1335916002635	conserved gate region; other site
1335916002636	putative PBP binding loops; other site
1335916002637	ABC-ATPase subunit interface; other site
1335916002638	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
1335916002639	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1335916002640	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916002641	dimer interface [polypeptide binding]; other site
1335916002642	conserved gate region; other site
1335916002643	putative PBP binding loops; other site
1335916002644	ABC-ATPase subunit interface; other site
1335916002645	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1335916002646	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1335916002647	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1335916002648	metal binding site [ion binding]; metal-binding site
1335916002649	active site
1335916002650	I-site; other site
1335916002651	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
1335916002652	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1335916002653	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916002654	FeS/SAM binding site; other site
1335916002655	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
1335916002656	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
1335916002657	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
1335916002658	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1335916002659	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1335916002660	putative C-terminal domain interface [polypeptide binding]; other site
1335916002661	putative GSH binding site (G-site) [chemical binding]; other site
1335916002662	putative dimer interface [polypeptide binding]; other site
1335916002663	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
1335916002664	N-terminal domain interface [polypeptide binding]; other site
1335916002665	dimer interface [polypeptide binding]; other site
1335916002666	substrate binding pocket (H-site) [chemical binding]; other site
1335916002667	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
1335916002668	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1335916002669	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1335916002670	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1335916002671	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1335916002672	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1335916002673	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1335916002674	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1335916002675	active site
1335916002676	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1335916002677	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916002678	putative substrate translocation pore; other site
1335916002679	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1335916002680	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916002681	active site
1335916002682	motif I; other site
1335916002683	motif II; other site
1335916002684	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916002685	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1335916002686	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916002687	putative substrate translocation pore; other site
1335916002688	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1335916002689	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
1335916002690	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1335916002691	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1335916002692	putative transporter; Provisional; Region: PRK04972
1335916002693	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1335916002694	TrkA-C domain; Region: TrkA_C; pfam02080
1335916002695	TrkA-C domain; Region: TrkA_C; pfam02080
1335916002696	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1335916002697	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
1335916002698	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
1335916002699	GSH binding site [chemical binding]; other site
1335916002700	catalytic residues [active]
1335916002701	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
1335916002702	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1335916002703	dimer interface [polypeptide binding]; other site
1335916002704	FMN binding site [chemical binding]; other site
1335916002705	NADPH bind site [chemical binding]; other site
1335916002706	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
1335916002707	RimK-like ATP-grasp domain; Region: RimK; pfam08443
1335916002708	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1335916002709	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
1335916002710	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1335916002711	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
1335916002712	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916002713	Walker A/P-loop; other site
1335916002714	ATP binding site [chemical binding]; other site
1335916002715	Q-loop/lid; other site
1335916002716	ABC transporter signature motif; other site
1335916002717	Walker B; other site
1335916002718	D-loop; other site
1335916002719	H-loop/switch region; other site
1335916002720	TOBE domain; Region: TOBE_2; pfam08402
1335916002721	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1335916002722	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916002723	dimer interface [polypeptide binding]; other site
1335916002724	conserved gate region; other site
1335916002725	putative PBP binding loops; other site
1335916002726	ABC-ATPase subunit interface; other site
1335916002727	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1335916002728	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916002729	dimer interface [polypeptide binding]; other site
1335916002730	conserved gate region; other site
1335916002731	putative PBP binding loops; other site
1335916002732	ABC-ATPase subunit interface; other site
1335916002733	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
1335916002734	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
1335916002735	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916002736	S-adenosylmethionine binding site [chemical binding]; other site
1335916002737	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1335916002738	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916002739	substrate binding pocket [chemical binding]; other site
1335916002740	membrane-bound complex binding site; other site
1335916002741	hinge residues; other site
1335916002742	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916002743	dimer interface [polypeptide binding]; other site
1335916002744	conserved gate region; other site
1335916002745	putative PBP binding loops; other site
1335916002746	ABC-ATPase subunit interface; other site
1335916002747	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1335916002748	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916002749	dimer interface [polypeptide binding]; other site
1335916002750	conserved gate region; other site
1335916002751	putative PBP binding loops; other site
1335916002752	ABC-ATPase subunit interface; other site
1335916002753	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1335916002754	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916002755	substrate binding pocket [chemical binding]; other site
1335916002756	membrane-bound complex binding site; other site
1335916002757	hinge residues; other site
1335916002758	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1335916002759	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916002760	Walker A/P-loop; other site
1335916002761	ATP binding site [chemical binding]; other site
1335916002762	Q-loop/lid; other site
1335916002763	ABC transporter signature motif; other site
1335916002764	Walker B; other site
1335916002765	D-loop; other site
1335916002766	H-loop/switch region; other site
1335916002767	putative lipoprotein; Provisional; Region: PRK10533
1335916002768	hypothetical protein; Provisional; Region: PRK02877
1335916002769	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1335916002770	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1335916002771	amidase catalytic site [active]
1335916002772	Zn binding residues [ion binding]; other site
1335916002773	substrate binding site [chemical binding]; other site
1335916002774	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1335916002775	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1335916002776	NAD(P) binding site [chemical binding]; other site
1335916002777	active site
1335916002778	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1335916002779	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
1335916002780	putative NAD(P) binding site [chemical binding]; other site
1335916002781	putative active site [active]
1335916002782	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
1335916002783	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1335916002784	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1335916002785	tetramer interface [polypeptide binding]; other site
1335916002786	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916002787	catalytic residue [active]
1335916002788	pyruvate dehydrogenase; Provisional; Region: PRK09124
1335916002789	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1335916002790	PYR/PP interface [polypeptide binding]; other site
1335916002791	dimer interface [polypeptide binding]; other site
1335916002792	tetramer interface [polypeptide binding]; other site
1335916002793	TPP binding site [chemical binding]; other site
1335916002794	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1335916002795	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1335916002796	TPP-binding site [chemical binding]; other site
1335916002797	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
1335916002798	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
1335916002799	FAD binding pocket [chemical binding]; other site
1335916002800	FAD binding motif [chemical binding]; other site
1335916002801	phosphate binding motif [ion binding]; other site
1335916002802	beta-alpha-beta structure motif; other site
1335916002803	NAD binding pocket [chemical binding]; other site
1335916002804	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1335916002805	catalytic loop [active]
1335916002806	iron binding site [ion binding]; other site
1335916002807	hybrid cluster protein; Provisional; Region: PRK05290
1335916002808	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1335916002809	ACS interaction site; other site
1335916002810	CODH interaction site; other site
1335916002811	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1335916002812	hybrid metal cluster; other site
1335916002813	Predicted membrane protein [Function unknown]; Region: COG2431
1335916002814	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1335916002815	amphipathic channel; other site
1335916002816	Asn-Pro-Ala signature motifs; other site
1335916002817	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1335916002818	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1335916002819	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1335916002820	putative active site [active]
1335916002821	putative metal-binding site [ion binding]; other site
1335916002822	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1335916002823	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1335916002824	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1335916002825	HlyD family secretion protein; Region: HlyD_3; pfam13437
1335916002826	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1335916002827	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1335916002828	Walker A/P-loop; other site
1335916002829	ATP binding site [chemical binding]; other site
1335916002830	Q-loop/lid; other site
1335916002831	ABC transporter signature motif; other site
1335916002832	Walker B; other site
1335916002833	D-loop; other site
1335916002834	H-loop/switch region; other site
1335916002835	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1335916002836	FtsX-like permease family; Region: FtsX; pfam02687
1335916002837	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1335916002838	DNA-binding site [nucleotide binding]; DNA binding site
1335916002839	RNA-binding motif; other site
1335916002840	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
1335916002841	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
1335916002842	Clp amino terminal domain; Region: Clp_N; pfam02861
1335916002843	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916002844	Walker A motif; other site
1335916002845	ATP binding site [chemical binding]; other site
1335916002846	Walker B motif; other site
1335916002847	arginine finger; other site
1335916002848	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916002849	Walker A motif; other site
1335916002850	ATP binding site [chemical binding]; other site
1335916002851	Walker B motif; other site
1335916002852	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1335916002853	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1335916002854	rRNA binding site [nucleotide binding]; other site
1335916002855	predicted 30S ribosome binding site; other site
1335916002856	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1335916002857	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1335916002858	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1335916002859	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
1335916002860	Walker A/P-loop; other site
1335916002861	ATP binding site [chemical binding]; other site
1335916002862	Q-loop/lid; other site
1335916002863	ABC transporter signature motif; other site
1335916002864	Walker B; other site
1335916002865	D-loop; other site
1335916002866	H-loop/switch region; other site
1335916002867	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1335916002868	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1335916002869	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916002870	Walker A/P-loop; other site
1335916002871	ATP binding site [chemical binding]; other site
1335916002872	Q-loop/lid; other site
1335916002873	ABC transporter signature motif; other site
1335916002874	Walker B; other site
1335916002875	D-loop; other site
1335916002876	H-loop/switch region; other site
1335916002877	thioredoxin reductase; Provisional; Region: PRK10262
1335916002878	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1335916002879	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916002880	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1335916002881	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1335916002882	putative DNA binding site [nucleotide binding]; other site
1335916002883	putative Zn2+ binding site [ion binding]; other site
1335916002884	AsnC family; Region: AsnC_trans_reg; pfam01037
1335916002885	DNA translocase FtsK; Provisional; Region: PRK10263
1335916002886	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1335916002887	DNA translocase FtsK; Provisional; Region: PRK10263
1335916002888	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1335916002889	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1335916002890	periplasmic chaperone LolA; Region: lolA; TIGR00547
1335916002891	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1335916002892	recombination factor protein RarA; Reviewed; Region: PRK13342
1335916002893	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916002894	Walker A motif; other site
1335916002895	ATP binding site [chemical binding]; other site
1335916002896	Walker B motif; other site
1335916002897	arginine finger; other site
1335916002898	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1335916002899	seryl-tRNA synthetase; Provisional; Region: PRK05431
1335916002900	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1335916002901	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1335916002902	dimer interface [polypeptide binding]; other site
1335916002903	active site
1335916002904	motif 1; other site
1335916002905	motif 2; other site
1335916002906	motif 3; other site
1335916002907	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
1335916002908	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1335916002909	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1335916002910	putative [Fe4-S4] binding site [ion binding]; other site
1335916002911	putative molybdopterin cofactor binding site [chemical binding]; other site
1335916002912	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1335916002913	putative molybdopterin cofactor binding site; other site
1335916002914	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1335916002915	4Fe-4S binding domain; Region: Fer4; pfam00037
1335916002916	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
1335916002917	Isochorismatase family; Region: Isochorismatase; pfam00857
1335916002918	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1335916002919	catalytic triad [active]
1335916002920	dimer interface [polypeptide binding]; other site
1335916002921	conserved cis-peptide bond; other site
1335916002922	putative MFS family transporter protein; Provisional; Region: PRK03633
1335916002923	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916002924	putative substrate translocation pore; other site
1335916002925	Amino acid permease; Region: AA_permease_2; pfam13520
1335916002926	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1335916002927	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916002928	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1335916002929	putative effector binding pocket; other site
1335916002930	putative dimerization interface [polypeptide binding]; other site
1335916002931	hypothetical protein; Provisional; Region: PRK09739
1335916002932	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1335916002933	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1335916002934	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916002935	FeS/SAM binding site; other site
1335916002936	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1335916002937	Pyruvate formate lyase 1; Region: PFL1; cd01678
1335916002938	coenzyme A binding site [chemical binding]; other site
1335916002939	active site
1335916002940	catalytic residues [active]
1335916002941	glycine loop; other site
1335916002942	formate transporter; Provisional; Region: PRK10805
1335916002943	uncharacterized domain; Region: TIGR00702
1335916002944	YcaO-like family; Region: YcaO; pfam02624
1335916002945	Predicted membrane protein [Function unknown]; Region: COG2323
1335916002946	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1335916002947	homodimer interface [polypeptide binding]; other site
1335916002948	substrate-cofactor binding pocket; other site
1335916002949	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916002950	catalytic residue [active]
1335916002951	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1335916002952	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
1335916002953	hinge; other site
1335916002954	active site
1335916002955	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1335916002956	cytidylate kinase; Provisional; Region: cmk; PRK00023
1335916002957	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1335916002958	CMP-binding site; other site
1335916002959	The sites determining sugar specificity; other site
1335916002960	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1335916002961	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1335916002962	RNA binding site [nucleotide binding]; other site
1335916002963	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1335916002964	RNA binding site [nucleotide binding]; other site
1335916002965	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
1335916002966	RNA binding site [nucleotide binding]; other site
1335916002967	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
1335916002968	RNA binding site [nucleotide binding]; other site
1335916002969	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1335916002970	RNA binding site [nucleotide binding]; other site
1335916002971	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1335916002972	IHF dimer interface [polypeptide binding]; other site
1335916002973	IHF - DNA interface [nucleotide binding]; other site
1335916002974	ComEC family competence protein; Provisional; Region: PRK11539
1335916002975	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1335916002976	ComEC/Rec2-related protein; Region: ComEC_N-term; TIGR00360
1335916002977	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1335916002978	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1335916002979	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1335916002980	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1335916002981	Walker A/P-loop; other site
1335916002982	ATP binding site [chemical binding]; other site
1335916002983	Q-loop/lid; other site
1335916002984	ABC transporter signature motif; other site
1335916002985	Walker B; other site
1335916002986	D-loop; other site
1335916002987	H-loop/switch region; other site
1335916002988	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1335916002989	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
1335916002990	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
1335916002991	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
1335916002992	hypothetical protein; Provisional; Region: PRK11827
1335916002993	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1335916002994	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1335916002995	Ligand binding site; other site
1335916002996	oligomer interface; other site
1335916002997	hypothetical protein; Provisional; Region: PRK10593
1335916002998	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1335916002999	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1335916003000	putative active site [active]
1335916003001	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1335916003002	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916003003	S-adenosylmethionine binding site [chemical binding]; other site
1335916003004	condesin subunit F; Provisional; Region: PRK05260
1335916003005	condesin subunit E; Provisional; Region: PRK05256
1335916003006	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
1335916003007	MukB N-terminal; Region: MukB; pfam04310
1335916003008	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1335916003009	murein L,D-transpeptidase; Provisional; Region: PRK10594
1335916003010	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1335916003011	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1335916003012	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1335916003013	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1335916003014	Peptidase M15; Region: Peptidase_M15_3; cl01194
1335916003015	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1335916003016	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1335916003017	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1335916003018	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916003019	homodimer interface [polypeptide binding]; other site
1335916003020	catalytic residue [active]
1335916003021	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1335916003022	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1335916003023	putative dimer interface [polypeptide binding]; other site
1335916003024	putative anticodon binding site; other site
1335916003025	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1335916003026	homodimer interface [polypeptide binding]; other site
1335916003027	motif 1; other site
1335916003028	motif 2; other site
1335916003029	active site
1335916003030	motif 3; other site
1335916003031	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1335916003032	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1335916003033	active site
1335916003034	aminopeptidase N; Provisional; Region: pepN; PRK14015
1335916003035	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1335916003036	active site
1335916003037	Zn binding site [ion binding]; other site
1335916003038	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
1335916003039	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1335916003040	Walker A/P-loop; other site
1335916003041	ATP binding site [chemical binding]; other site
1335916003042	Q-loop/lid; other site
1335916003043	ABC transporter signature motif; other site
1335916003044	Walker B; other site
1335916003045	D-loop; other site
1335916003046	H-loop/switch region; other site
1335916003047	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1335916003048	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916003049	dimer interface [polypeptide binding]; other site
1335916003050	conserved gate region; other site
1335916003051	putative PBP binding loops; other site
1335916003052	ABC-ATPase subunit interface; other site
1335916003053	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
1335916003054	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1335916003055	active site
1335916003056	dimer interface [polypeptide binding]; other site
1335916003057	non-prolyl cis peptide bond; other site
1335916003058	insertion regions; other site
1335916003059	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916003060	substrate binding pocket [chemical binding]; other site
1335916003061	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1335916003062	membrane-bound complex binding site; other site
1335916003063	hinge residues; other site
1335916003064	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
1335916003065	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1335916003066	Fimbrial protein; Region: Fimbrial; cl01416
1335916003067	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1335916003068	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1335916003069	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1335916003070	outer membrane usher protein; Provisional; Region: PRK15193
1335916003071	PapC N-terminal domain; Region: PapC_N; pfam13954
1335916003072	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1335916003073	PapC C-terminal domain; Region: PapC_C; pfam13953
1335916003074	Fimbrial protein; Region: Fimbrial; cl01416
1335916003075	Fimbrial protein; Region: Fimbrial; cl01416
1335916003076	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1335916003077	putativi pili assembly chaperone; Provisional; Region: PRK11385
1335916003078	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1335916003079	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1335916003080	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1335916003081	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1335916003082	quinone interaction residues [chemical binding]; other site
1335916003083	active site
1335916003084	catalytic residues [active]
1335916003085	FMN binding site [chemical binding]; other site
1335916003086	substrate binding site [chemical binding]; other site
1335916003087	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
1335916003088	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1335916003089	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1335916003090	MOSC domain; Region: MOSC; pfam03473
1335916003091	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1335916003092	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1335916003093	catalytic loop [active]
1335916003094	iron binding site [ion binding]; other site
1335916003095	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1335916003096	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1335916003097	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1335916003098	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916003099	S-adenosylmethionine binding site [chemical binding]; other site
1335916003100	ABC transporter ATPase component; Reviewed; Region: PRK11147
1335916003101	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916003102	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916003103	Walker A/P-loop; other site
1335916003104	Walker A/P-loop; other site
1335916003105	ATP binding site [chemical binding]; other site
1335916003106	ATP binding site [chemical binding]; other site
1335916003107	Q-loop/lid; other site
1335916003108	Q-loop/lid; other site
1335916003109	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1335916003110	ABC transporter signature motif; other site
1335916003111	Walker B; other site
1335916003112	D-loop; other site
1335916003113	ABC transporter; Region: ABC_tran_2; pfam12848
1335916003114	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1335916003115	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
1335916003116	Paraquat-inducible protein A; Region: PqiA; pfam04403
1335916003117	Paraquat-inducible protein A; Region: PqiA; pfam04403
1335916003118	paraquat-inducible protein B; Provisional; Region: PRK10807
1335916003119	mce related protein; Region: MCE; pfam02470
1335916003120	mce related protein; Region: MCE; pfam02470
1335916003121	mce related protein; Region: MCE; pfam02470
1335916003122	DASH complex subunit Duo1; Region: DASH_Duo1; pfam08651
1335916003123	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1335916003124	Protein of unknown function (DUF330); Region: DUF330; pfam03886
1335916003125	ribosome modulation factor; Provisional; Region: PRK14563
1335916003126	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1335916003127	active site 1 [active]
1335916003128	dimer interface [polypeptide binding]; other site
1335916003129	active site 2 [active]
1335916003130	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1335916003131	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1335916003132	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
1335916003133	outer membrane protein A; Reviewed; Region: PRK10808
1335916003134	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1335916003135	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1335916003136	ligand binding site [chemical binding]; other site
1335916003137	cell division inhibitor SulA; Region: sula; TIGR00623
1335916003138	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
1335916003139	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1335916003140	TIGR01666 family membrane protein; Region: YCCS
1335916003141	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1335916003142	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1335916003143	Predicted membrane protein [Function unknown]; Region: COG3304
1335916003144	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1335916003145	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1335916003146	DNA helicase IV; Provisional; Region: helD; PRK11054
1335916003147	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
1335916003148	Part of AAA domain; Region: AAA_19; pfam13245
1335916003149	Family description; Region: UvrD_C_2; pfam13538
1335916003150	hypothetical protein; Provisional; Region: PRK03641
1335916003151	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
1335916003152	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1335916003153	heat shock protein HspQ; Provisional; Region: PRK14129
1335916003154	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
1335916003155	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1335916003156	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1335916003157	putative RNA binding site [nucleotide binding]; other site
1335916003158	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916003159	S-adenosylmethionine binding site [chemical binding]; other site
1335916003160	Acylphosphatase; Region: Acylphosphatase; cl00551
1335916003161	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1335916003162	sulfur transfer protein TusE; Provisional; Region: PRK11508
1335916003163	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1335916003164	YccA-like proteins; Region: YccA_like; cd10433
1335916003165	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
1335916003166	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1335916003167	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1335916003168	hydrogenase 1 large subunit; Provisional; Region: PRK10170
1335916003169	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1335916003170	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
1335916003171	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1335916003172	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1335916003173	putative substrate-binding site; other site
1335916003174	nickel binding site [ion binding]; other site
1335916003175	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
1335916003176	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1335916003177	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
1335916003178	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1335916003179	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
1335916003180	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1335916003181	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1335916003182	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1335916003183	catalytic core [active]
1335916003184	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1335916003185	cryptic autophosphorylating protein tyrosine kinase Etk; Provisional; Region: PRK09841
1335916003186	Chain length determinant protein; Region: Wzz; pfam02706
1335916003187	Chain length determinant protein; Region: Wzz; cl15801
1335916003188	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1335916003189	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
1335916003190	Nucleotide binding site [chemical binding]; other site
1335916003191	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1335916003192	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1335916003193	active site
1335916003194	polysaccharide export protein Wza; Provisional; Region: PRK15078
1335916003195	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1335916003196	SLBB domain; Region: SLBB; pfam10531
1335916003197	SLBB domain; Region: SLBB; pfam10531
1335916003198	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
1335916003199	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
1335916003200	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
1335916003201	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1335916003202	DNA-binding site [nucleotide binding]; DNA binding site
1335916003203	RNA-binding motif; other site
1335916003204	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1335916003205	DNA-binding site [nucleotide binding]; DNA binding site
1335916003206	RNA-binding motif; other site
1335916003207	cold shock gene; Provisional; Region: PRK09891
1335916003208	GnsA/GnsB family; Region: GnsAB; pfam08178
1335916003209	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
1335916003210	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1335916003211	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1335916003212	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1335916003213	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
1335916003214	HAMP domain; Region: HAMP; pfam00672
1335916003215	dimerization interface [polypeptide binding]; other site
1335916003216	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916003217	dimer interface [polypeptide binding]; other site
1335916003218	phosphorylation site [posttranslational modification]
1335916003219	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916003220	ATP binding site [chemical binding]; other site
1335916003221	Mg2+ binding site [ion binding]; other site
1335916003222	G-X-G motif; other site
1335916003223	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916003224	active site
1335916003225	phosphorylation site [posttranslational modification]
1335916003226	intermolecular recognition site; other site
1335916003227	dimerization interface [polypeptide binding]; other site
1335916003228	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1335916003229	putative binding surface; other site
1335916003230	active site
1335916003231	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
1335916003232	TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria; Region: PBP1_TorT-like; cd06306
1335916003233	putative ligand binding site [chemical binding]; other site
1335916003234	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
1335916003235	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916003236	active site
1335916003237	phosphorylation site [posttranslational modification]
1335916003238	intermolecular recognition site; other site
1335916003239	dimerization interface [polypeptide binding]; other site
1335916003240	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1335916003241	DNA binding site [nucleotide binding]
1335916003242	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
1335916003243	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
1335916003244	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
1335916003245	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1335916003246	molybdopterin cofactor binding site [chemical binding]; other site
1335916003247	substrate binding site [chemical binding]; other site
1335916003248	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1335916003249	molybdopterin cofactor binding site; other site
1335916003250	chaperone protein TorD; Validated; Region: torD; PRK04976
1335916003251	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
1335916003252	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
1335916003253	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
1335916003254	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1335916003255	HSP70 interaction site [polypeptide binding]; other site
1335916003256	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1335916003257	substrate binding site [polypeptide binding]; other site
1335916003258	dimer interface [polypeptide binding]; other site
1335916003259	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1335916003260	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1335916003261	catalytic core [active]
1335916003262	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1335916003263	hypothetical protein; Provisional; Region: PRK10174
1335916003264	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
1335916003265	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1335916003266	General stress protein [General function prediction only]; Region: GsiB; COG3729
1335916003267	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
1335916003268	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
1335916003269	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
1335916003270	putative FMN binding site [chemical binding]; other site
1335916003271	pyrimidine utilization protein D; Region: RutD; TIGR03611
1335916003272	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1335916003273	homotrimer interaction site [polypeptide binding]; other site
1335916003274	putative active site [active]
1335916003275	Isochorismatase family; Region: Isochorismatase; pfam00857
1335916003276	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1335916003277	catalytic triad [active]
1335916003278	conserved cis-peptide bond; other site
1335916003279	pyrimidine utilization protein A; Region: RutA; TIGR03612
1335916003280	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1335916003281	active site
1335916003282	dimer interface [polypeptide binding]; other site
1335916003283	non-prolyl cis peptide bond; other site
1335916003284	insertion regions; other site
1335916003285	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1335916003286	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
1335916003287	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1335916003288	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
1335916003289	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
1335916003290	Predicted transcriptional regulator [Transcription]; Region: COG3905
1335916003291	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
1335916003292	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1335916003293	Glutamate binding site [chemical binding]; other site
1335916003294	NAD binding site [chemical binding]; other site
1335916003295	catalytic residues [active]
1335916003296	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1335916003297	Na binding site [ion binding]; other site
1335916003298	FTR1 family protein; Region: TIGR00145
1335916003299	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
1335916003300	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
1335916003301	Imelysin; Region: Peptidase_M75; pfam09375
1335916003302	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
1335916003303	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
1335916003304	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1335916003305	hypothetical protein; Provisional; Region: PRK10536
1335916003306	putative PGA biosynthesis protein; Provisional; Region: pgaD; PRK14585
1335916003307	N-glycosyltransferase; Provisional; Region: PRK11204
1335916003308	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
1335916003309	DXD motif; other site
1335916003310	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
1335916003311	outer membrane N-deacetylase; Provisional; Region: pgaB; PRK14582
1335916003312	N-terminal putative catalytic polysaccharide deacetylase domain of bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, and similar proteins; Region: CE4_PgaB_5s; cd10964
1335916003313	putative active site [active]
1335916003314	putative metal binding site [ion binding]; other site
1335916003315	outer membrane protein PgaA; Provisional; Region: pgaA; PRK10049
1335916003316	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916003317	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1335916003318	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1335916003319	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
1335916003320	curli assembly protein CsgF; Provisional; Region: PRK10050
1335916003321	curli assembly protein CsgE; Provisional; Region: PRK10386
1335916003322	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
1335916003323	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916003324	DNA binding residues [nucleotide binding]
1335916003325	dimerization interface [polypeptide binding]; other site
1335916003326	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
1335916003327	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1335916003328	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1335916003329	major curlin subunit; Provisional; Region: csgA; PRK10051
1335916003330	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1335916003331	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1335916003332	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
1335916003333	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1335916003334	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1335916003335	putative ADP-ribose binding site [chemical binding]; other site
1335916003336	putative active site [active]
1335916003337	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
1335916003338	PLD-like domain; Region: PLDc_2; pfam13091
1335916003339	putative active site [active]
1335916003340	catalytic site [active]
1335916003341	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
1335916003342	PLD-like domain; Region: PLDc_2; pfam13091
1335916003343	putative active site [active]
1335916003344	catalytic site [active]
1335916003345	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
1335916003346	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1335916003347	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
1335916003348	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
1335916003349	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1335916003350	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
1335916003351	Ligand binding site; other site
1335916003352	DXD motif; other site
1335916003353	lipoprotein; Provisional; Region: PRK10175
1335916003354	secY/secA suppressor protein; Provisional; Region: PRK11467
1335916003355	drug efflux system protein MdtG; Provisional; Region: PRK09874
1335916003356	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916003357	putative substrate translocation pore; other site
1335916003358	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1335916003359	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1335916003360	putative acyl-acceptor binding pocket; other site
1335916003361	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1335916003362	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1335916003363	active site residue [active]
1335916003364	hypothetical protein; Provisional; Region: PRK03757
1335916003365	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1335916003366	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
1335916003367	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
1335916003368	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1335916003369	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
1335916003370	DNA damage-inducible protein I; Provisional; Region: PRK10597
1335916003371	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1335916003372	active site
1335916003373	substrate binding pocket [chemical binding]; other site
1335916003374	dimer interface [polypeptide binding]; other site
1335916003375	lipoprotein; Provisional; Region: PRK10598
1335916003376	glutaredoxin 2; Provisional; Region: PRK10387
1335916003377	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
1335916003378	C-terminal domain interface [polypeptide binding]; other site
1335916003379	GSH binding site (G-site) [chemical binding]; other site
1335916003380	catalytic residues [active]
1335916003381	putative dimer interface [polypeptide binding]; other site
1335916003382	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
1335916003383	N-terminal domain interface [polypeptide binding]; other site
1335916003384	multidrug resistance protein MdtH; Provisional; Region: PRK11646
1335916003385	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916003386	putative substrate translocation pore; other site
1335916003387	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
1335916003388	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1335916003389	hypothetical protein; Provisional; Region: PRK11239
1335916003390	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
1335916003391	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1335916003392	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1335916003393	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1335916003394	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1335916003395	MviN-like protein; Region: MVIN; pfam03023
1335916003396	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
1335916003397	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
1335916003398	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1335916003399	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1335916003400	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1335916003401	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
1335916003402	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1335916003403	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1335916003404	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1335916003405	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1335916003406	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1335916003407	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1335916003408	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
1335916003409	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1335916003410	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1335916003411	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1335916003412	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1335916003413	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1335916003414	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1335916003415	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1335916003416	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1335916003417	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1335916003418	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
1335916003419	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1335916003420	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1335916003421	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
1335916003422	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1335916003423	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
1335916003424	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
1335916003425	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1335916003426	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
1335916003427	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1335916003428	homodimer interface [polypeptide binding]; other site
1335916003429	oligonucleotide binding site [chemical binding]; other site
1335916003430	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
1335916003431	Protein of unknown function (DUF2655); Region: DUF2655; pfam10848
1335916003432	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1335916003433	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1335916003434	RNA binding surface [nucleotide binding]; other site
1335916003435	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1335916003436	active site
1335916003437	Maf-like protein; Region: Maf; pfam02545
1335916003438	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1335916003439	active site
1335916003440	dimer interface [polypeptide binding]; other site
1335916003441	hypothetical protein; Provisional; Region: PRK11193
1335916003442	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1335916003443	putative phosphate acyltransferase; Provisional; Region: PRK05331
1335916003444	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1335916003445	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1335916003446	dimer interface [polypeptide binding]; other site
1335916003447	active site
1335916003448	CoA binding pocket [chemical binding]; other site
1335916003449	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1335916003450	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1335916003451	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1335916003452	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1335916003453	NAD(P) binding site [chemical binding]; other site
1335916003454	homotetramer interface [polypeptide binding]; other site
1335916003455	homodimer interface [polypeptide binding]; other site
1335916003456	active site
1335916003457	acyl carrier protein; Provisional; Region: acpP; PRK00982
1335916003458	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1335916003459	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1335916003460	dimer interface [polypeptide binding]; other site
1335916003461	active site
1335916003462	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1335916003463	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1335916003464	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916003465	catalytic residue [active]
1335916003466	conserved hypothetical protein, YceG family; Region: TIGR00247
1335916003467	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1335916003468	dimerization interface [polypeptide binding]; other site
1335916003469	thymidylate kinase; Validated; Region: tmk; PRK00698
1335916003470	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1335916003471	TMP-binding site; other site
1335916003472	ATP-binding site [chemical binding]; other site
1335916003473	DNA polymerase III subunit delta'; Validated; Region: PRK07993
1335916003474	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1335916003475	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1335916003476	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1335916003477	active site
1335916003478	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
1335916003479	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1335916003480	N-terminal plug; other site
1335916003481	ligand-binding site [chemical binding]; other site
1335916003482	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1335916003483	nucleotide binding site/active site [active]
1335916003484	HIT family signature motif; other site
1335916003485	catalytic residue [active]
1335916003486	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
1335916003487	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1335916003488	putative dimer interface [polypeptide binding]; other site
1335916003489	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
1335916003490	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1335916003491	beta-hexosaminidase; Provisional; Region: PRK05337
1335916003492	hypothetical protein; Provisional; Region: PRK04940
1335916003493	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1335916003494	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916003495	hypothetical protein; Provisional; Region: PRK11280
1335916003496	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1335916003497	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1335916003498	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1335916003499	L,D-transpeptidase; Provisional; Region: PRK10260
1335916003500	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1335916003501	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1335916003502	transcription-repair coupling factor; Provisional; Region: PRK10689
1335916003503	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1335916003504	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1335916003505	ATP binding site [chemical binding]; other site
1335916003506	putative Mg++ binding site [ion binding]; other site
1335916003507	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1335916003508	nucleotide binding region [chemical binding]; other site
1335916003509	ATP-binding site [chemical binding]; other site
1335916003510	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1335916003511	Predicted membrane protein [Function unknown]; Region: COG4763
1335916003512	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1335916003513	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
1335916003514	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1335916003515	FtsX-like permease family; Region: FtsX; pfam02687
1335916003516	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
1335916003517	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1335916003518	Walker A/P-loop; other site
1335916003519	ATP binding site [chemical binding]; other site
1335916003520	Q-loop/lid; other site
1335916003521	ABC transporter signature motif; other site
1335916003522	Walker B; other site
1335916003523	D-loop; other site
1335916003524	H-loop/switch region; other site
1335916003525	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1335916003526	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1335916003527	FtsX-like permease family; Region: FtsX; pfam02687
1335916003528	NAD-dependent deacetylase; Provisional; Region: PRK00481
1335916003529	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1335916003530	NAD+ binding site [chemical binding]; other site
1335916003531	substrate binding site [chemical binding]; other site
1335916003532	Zn binding site [ion binding]; other site
1335916003533	Repair protein; Region: Repair_PSII; cl01535
1335916003534	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
1335916003535	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
1335916003536	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1335916003537	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1335916003538	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916003539	dimer interface [polypeptide binding]; other site
1335916003540	conserved gate region; other site
1335916003541	putative PBP binding loops; other site
1335916003542	ABC-ATPase subunit interface; other site
1335916003543	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1335916003544	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916003545	dimer interface [polypeptide binding]; other site
1335916003546	conserved gate region; other site
1335916003547	putative PBP binding loops; other site
1335916003548	ABC-ATPase subunit interface; other site
1335916003549	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
1335916003550	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916003551	Walker A/P-loop; other site
1335916003552	ATP binding site [chemical binding]; other site
1335916003553	Q-loop/lid; other site
1335916003554	ABC transporter signature motif; other site
1335916003555	Walker B; other site
1335916003556	D-loop; other site
1335916003557	H-loop/switch region; other site
1335916003558	TOBE domain; Region: TOBE_2; pfam08402
1335916003559	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1335916003560	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1335916003561	metal binding site [ion binding]; metal-binding site
1335916003562	dimer interface [polypeptide binding]; other site
1335916003563	sensor protein PhoQ; Provisional; Region: PRK10815
1335916003564	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1335916003565	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1335916003566	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1335916003567	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916003568	ATP binding site [chemical binding]; other site
1335916003569	Mg2+ binding site [ion binding]; other site
1335916003570	G-X-G motif; other site
1335916003571	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
1335916003572	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916003573	active site
1335916003574	phosphorylation site [posttranslational modification]
1335916003575	intermolecular recognition site; other site
1335916003576	dimerization interface [polypeptide binding]; other site
1335916003577	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1335916003578	DNA binding site [nucleotide binding]
1335916003579	adenylosuccinate lyase; Provisional; Region: PRK09285
1335916003580	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1335916003581	tetramer interface [polypeptide binding]; other site
1335916003582	active site
1335916003583	putative lysogenization regulator; Reviewed; Region: PRK00218
1335916003584	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1335916003585	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1335916003586	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
1335916003587	nudix motif; other site
1335916003588	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
1335916003589	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
1335916003590	probable active site [active]
1335916003591	isocitrate dehydrogenase; Validated; Region: PRK07362
1335916003592	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1335916003593	anti-adapter protein IraM; Provisional; Region: PRK09919
1335916003594	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
1335916003595	transcriptional regulator MirA; Provisional; Region: PRK15043
1335916003596	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1335916003597	DNA binding residues [nucleotide binding]
1335916003598	Sensors of blue-light using FAD; Region: BLUF; smart01034
1335916003599	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1335916003600	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1335916003601	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1335916003602	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1335916003603	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1335916003604	heme ABC transporter, heme-binding protein isdE; Region: IsdE; TIGR03659
1335916003605	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1335916003606	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1335916003607	Autotransporter beta-domain; Region: Autotransporter; smart00869
1335916003608	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1335916003609	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1335916003610	cell division inhibitor MinD; Provisional; Region: PRK10818
1335916003611	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1335916003612	Switch I; other site
1335916003613	Switch II; other site
1335916003614	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1335916003615	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1335916003616	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1335916003617	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
1335916003618	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
1335916003619	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
1335916003620	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
1335916003621	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1335916003622	hypothetical protein; Provisional; Region: PRK10691
1335916003623	hypothetical protein; Provisional; Region: PRK05170
1335916003624	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1335916003625	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1335916003626	Catalytic site [active]
1335916003627	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1335916003628	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1335916003629	active site
1335916003630	DNA binding site [nucleotide binding]
1335916003631	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1335916003632	disulfide bond formation protein B; Provisional; Region: PRK01749
1335916003633	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1335916003634	transmembrane helices; other site
1335916003635	fatty acid metabolism regulator; Provisional; Region: PRK04984
1335916003636	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916003637	DNA-binding site [nucleotide binding]; DNA binding site
1335916003638	FadR C-terminal domain; Region: FadR_C; pfam07840
1335916003639	SpoVR family protein; Provisional; Region: PRK11767
1335916003640	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
1335916003641	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
1335916003642	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916003643	alanine racemase; Reviewed; Region: dadX; PRK03646
1335916003644	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1335916003645	active site
1335916003646	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1335916003647	substrate binding site [chemical binding]; other site
1335916003648	catalytic residues [active]
1335916003649	dimer interface [polypeptide binding]; other site
1335916003650	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
1335916003651	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1335916003652	TrkA-C domain; Region: TrkA_C; pfam02080
1335916003653	Transporter associated domain; Region: CorC_HlyC; smart01091
1335916003654	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1335916003655	dimer interface [polypeptide binding]; other site
1335916003656	catalytic triad [active]
1335916003657	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
1335916003658	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1335916003659	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1335916003660	catalytic residue [active]
1335916003661	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
1335916003662	Flagellar regulator YcgR; Region: YcgR; pfam07317
1335916003663	PilZ domain; Region: PilZ; pfam07238
1335916003664	hypothetical protein; Provisional; Region: PRK10457
1335916003665	trehalase; Provisional; Region: treA; PRK13271
1335916003666	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
1335916003667	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
1335916003668	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3412
1335916003669	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1335916003670	dimerization domain swap beta strand [polypeptide binding]; other site
1335916003671	regulatory protein interface [polypeptide binding]; other site
1335916003672	active site
1335916003673	regulatory phosphorylation site [posttranslational modification]; other site
1335916003674	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1335916003675	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1335916003676	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
1335916003677	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
1335916003678	Dak1 domain; Region: Dak1; pfam02733
1335916003679	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
1335916003680	PAS domain; Region: PAS; smart00091
1335916003681	putative active site [active]
1335916003682	heme pocket [chemical binding]; other site
1335916003683	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916003684	Walker A motif; other site
1335916003685	ATP binding site [chemical binding]; other site
1335916003686	Walker B motif; other site
1335916003687	arginine finger; other site
1335916003688	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1335916003689	GTP-binding protein YchF; Reviewed; Region: PRK09601
1335916003690	YchF GTPase; Region: YchF; cd01900
1335916003691	G1 box; other site
1335916003692	GTP/Mg2+ binding site [chemical binding]; other site
1335916003693	Switch I region; other site
1335916003694	G2 box; other site
1335916003695	Switch II region; other site
1335916003696	G3 box; other site
1335916003697	G4 box; other site
1335916003698	G5 box; other site
1335916003699	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1335916003700	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1335916003701	putative active site [active]
1335916003702	catalytic residue [active]
1335916003703	hypothetical protein; Provisional; Region: PRK10692
1335916003704	putative transporter; Provisional; Region: PRK11660
1335916003705	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1335916003706	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1335916003707	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1335916003708	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1335916003709	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1335916003710	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1335916003711	active site
1335916003712	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1335916003713	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1335916003714	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1335916003715	outer membrane lipoprotein LolB; Region: lolB; TIGR00548
1335916003716	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
1335916003717	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1335916003718	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1335916003719	tRNA; other site
1335916003720	putative tRNA binding site [nucleotide binding]; other site
1335916003721	putative NADP binding site [chemical binding]; other site
1335916003722	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1335916003723	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1335916003724	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1335916003725	RF-1 domain; Region: RF-1; pfam00472
1335916003726	HemK family putative methylases; Region: hemK_fam; TIGR00536
1335916003727	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916003728	hypothetical protein; Provisional; Region: PRK10278
1335916003729	hypothetical protein; Provisional; Region: PRK10941
1335916003730	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1335916003731	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1335916003732	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1335916003733	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1335916003734	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1335916003735	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1335916003736	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
1335916003737	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1335916003738	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916003739	cation transport regulator; Reviewed; Region: chaB; PRK09582
1335916003740	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
1335916003741	putative invasin; Provisional; Region: PRK10177
1335916003742	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1335916003743	transcriptional regulator NarL; Provisional; Region: PRK10651
1335916003744	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916003745	active site
1335916003746	phosphorylation site [posttranslational modification]
1335916003747	intermolecular recognition site; other site
1335916003748	dimerization interface [polypeptide binding]; other site
1335916003749	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916003750	DNA binding residues [nucleotide binding]
1335916003751	dimerization interface [polypeptide binding]; other site
1335916003752	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
1335916003753	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1335916003754	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1335916003755	dimerization interface [polypeptide binding]; other site
1335916003756	Histidine kinase; Region: HisKA_3; pfam07730
1335916003757	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916003758	ATP binding site [chemical binding]; other site
1335916003759	Mg2+ binding site [ion binding]; other site
1335916003760	G-X-G motif; other site
1335916003761	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1335916003762	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
1335916003763	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1335916003764	[4Fe-4S] binding site [ion binding]; other site
1335916003765	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1335916003766	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1335916003767	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1335916003768	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1335916003769	molybdopterin cofactor binding site; other site
1335916003770	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1335916003771	4Fe-4S binding domain; Region: Fer4; cl02805
1335916003772	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1335916003773	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1335916003774	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1335916003775	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1335916003776	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1335916003777	putative active site [active]
1335916003778	putative substrate binding site [chemical binding]; other site
1335916003779	putative cosubstrate binding site; other site
1335916003780	catalytic site [active]
1335916003781	hypothetical protein; Provisional; Region: PRK01617
1335916003782	hypothetical protein; Provisional; Region: PRK10279
1335916003783	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
1335916003784	active site
1335916003785	nucleophile elbow; other site
1335916003786	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916003787	active site
1335916003788	response regulator of RpoS; Provisional; Region: PRK10693
1335916003789	phosphorylation site [posttranslational modification]
1335916003790	intermolecular recognition site; other site
1335916003791	dimerization interface [polypeptide binding]; other site
1335916003792	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1335916003793	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1335916003794	active site
1335916003795	tetramer interface; other site
1335916003796	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1335916003797	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1335916003798	thymidine kinase; Provisional; Region: PRK04296
1335916003799	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
1335916003800	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1335916003801	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1335916003802	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1335916003803	hypothetical protein; Provisional; Region: PRK11111
1335916003804	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1335916003805	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1335916003806	peptide binding site [polypeptide binding]; other site
1335916003807	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1335916003808	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916003809	dimer interface [polypeptide binding]; other site
1335916003810	conserved gate region; other site
1335916003811	putative PBP binding loops; other site
1335916003812	ABC-ATPase subunit interface; other site
1335916003813	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1335916003814	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1335916003815	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916003816	dimer interface [polypeptide binding]; other site
1335916003817	conserved gate region; other site
1335916003818	putative PBP binding loops; other site
1335916003819	ABC-ATPase subunit interface; other site
1335916003820	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1335916003821	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1335916003822	Walker A/P-loop; other site
1335916003823	ATP binding site [chemical binding]; other site
1335916003824	Q-loop/lid; other site
1335916003825	ABC transporter signature motif; other site
1335916003826	Walker B; other site
1335916003827	D-loop; other site
1335916003828	H-loop/switch region; other site
1335916003829	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1335916003830	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1335916003831	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1335916003832	Walker A/P-loop; other site
1335916003833	ATP binding site [chemical binding]; other site
1335916003834	Q-loop/lid; other site
1335916003835	ABC transporter signature motif; other site
1335916003836	Walker B; other site
1335916003837	D-loop; other site
1335916003838	H-loop/switch region; other site
1335916003839	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1335916003840	dsDNA-mimic protein; Reviewed; Region: PRK05094
1335916003841	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1335916003842	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1335916003843	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1335916003844	putative active site [active]
1335916003845	catalytic site [active]
1335916003846	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1335916003847	putative active site [active]
1335916003848	catalytic site [active]
1335916003849	voltage-gated potassium channel; Provisional; Region: PRK10537
1335916003850	Ion channel; Region: Ion_trans_2; pfam07885
1335916003851	TrkA-N domain; Region: TrkA_N; pfam02254
1335916003852	YciI-like protein; Reviewed; Region: PRK11370
1335916003853	transport protein TonB; Provisional; Region: PRK10819
1335916003854	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1335916003855	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1335916003856	intracellular septation protein A; Reviewed; Region: PRK00259
1335916003857	hypothetical protein; Provisional; Region: PRK02868
1335916003858	outer membrane protein W; Provisional; Region: PRK10959
1335916003859	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3685
1335916003860	General stress protein [General function prediction only]; Region: GsiB; COG3729
1335916003861	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1335916003862	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1335916003863	substrate binding site [chemical binding]; other site
1335916003864	active site
1335916003865	catalytic residues [active]
1335916003866	heterodimer interface [polypeptide binding]; other site
1335916003867	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1335916003868	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1335916003869	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916003870	catalytic residue [active]
1335916003871	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1335916003872	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1335916003873	active site
1335916003874	ribulose/triose binding site [chemical binding]; other site
1335916003875	phosphate binding site [ion binding]; other site
1335916003876	substrate (anthranilate) binding pocket [chemical binding]; other site
1335916003877	product (indole) binding pocket [chemical binding]; other site
1335916003878	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1335916003879	active site
1335916003880	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
1335916003881	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1335916003882	glutamine binding [chemical binding]; other site
1335916003883	catalytic triad [active]
1335916003884	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1335916003885	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1335916003886	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1335916003887	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1335916003888	active site
1335916003889	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1335916003890	hypothetical protein; Provisional; Region: PRK11630
1335916003891	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1335916003892	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1335916003893	RNA binding surface [nucleotide binding]; other site
1335916003894	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1335916003895	probable active site [active]
1335916003896	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1335916003897	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
1335916003898	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
1335916003899	homodimer interface [polypeptide binding]; other site
1335916003900	Walker A motif; other site
1335916003901	ATP binding site [chemical binding]; other site
1335916003902	hydroxycobalamin binding site [chemical binding]; other site
1335916003903	Walker B motif; other site
1335916003904	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
1335916003905	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
1335916003906	NADP binding site [chemical binding]; other site
1335916003907	homodimer interface [polypeptide binding]; other site
1335916003908	active site
1335916003909	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1335916003910	putative inner membrane peptidase; Provisional; Region: PRK11778
1335916003911	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1335916003912	tandem repeat interface [polypeptide binding]; other site
1335916003913	oligomer interface [polypeptide binding]; other site
1335916003914	active site residues [active]
1335916003915	hypothetical protein; Provisional; Region: PRK11037
1335916003916	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1335916003917	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1335916003918	active site
1335916003919	interdomain interaction site; other site
1335916003920	putative metal-binding site [ion binding]; other site
1335916003921	nucleotide binding site [chemical binding]; other site
1335916003922	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1335916003923	domain I; other site
1335916003924	DNA binding groove [nucleotide binding]
1335916003925	phosphate binding site [ion binding]; other site
1335916003926	domain II; other site
1335916003927	domain III; other site
1335916003928	nucleotide binding site [chemical binding]; other site
1335916003929	catalytic site [active]
1335916003930	domain IV; other site
1335916003931	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1335916003932	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1335916003933	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1335916003934	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1335916003935	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1335916003936	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916003937	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
1335916003938	substrate binding site [chemical binding]; other site
1335916003939	putative dimerization interface [polypeptide binding]; other site
1335916003940	aconitate hydratase; Validated; Region: PRK09277
1335916003941	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1335916003942	substrate binding site [chemical binding]; other site
1335916003943	ligand binding site [chemical binding]; other site
1335916003944	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1335916003945	substrate binding site [chemical binding]; other site
1335916003946	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1335916003947	dimerization interface [polypeptide binding]; other site
1335916003948	active site
1335916003949	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1335916003950	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1335916003951	active site
1335916003952	Predicted membrane protein [Function unknown]; Region: COG3771
1335916003953	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
1335916003954	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1335916003955	TPR motif; other site
1335916003956	binding surface
1335916003957	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1335916003958	binding surface
1335916003959	TPR motif; other site
1335916003960	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1335916003961	active site
1335916003962	dimer interface [polypeptide binding]; other site
1335916003963	translation initiation factor Sui1; Validated; Region: PRK06824
1335916003964	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1335916003965	putative rRNA binding site [nucleotide binding]; other site
1335916003966	lipoprotein; Provisional; Region: PRK10540
1335916003967	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1335916003968	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1335916003969	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1335916003970	hypothetical protein; Provisional; Region: PRK13658
1335916003971	RNase II stability modulator; Provisional; Region: PRK10060
1335916003972	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1335916003973	putative active site [active]
1335916003974	heme pocket [chemical binding]; other site
1335916003975	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1335916003976	metal binding site [ion binding]; metal-binding site
1335916003977	active site
1335916003978	I-site; other site
1335916003979	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1335916003980	exoribonuclease II; Provisional; Region: PRK05054
1335916003981	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1335916003982	RNB domain; Region: RNB; pfam00773
1335916003983	S1 RNA binding domain; Region: S1; pfam00575
1335916003984	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
1335916003985	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1335916003986	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
1335916003987	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1335916003988	NAD binding site [chemical binding]; other site
1335916003989	homotetramer interface [polypeptide binding]; other site
1335916003990	homodimer interface [polypeptide binding]; other site
1335916003991	substrate binding site [chemical binding]; other site
1335916003992	active site
1335916003993	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
1335916003994	putative active site [active]
1335916003995	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
1335916003996	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1335916003997	Walker A/P-loop; other site
1335916003998	ATP binding site [chemical binding]; other site
1335916003999	Q-loop/lid; other site
1335916004000	ABC transporter signature motif; other site
1335916004001	Walker B; other site
1335916004002	D-loop; other site
1335916004003	H-loop/switch region; other site
1335916004004	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
1335916004005	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1335916004006	Walker A/P-loop; other site
1335916004007	ATP binding site [chemical binding]; other site
1335916004008	Q-loop/lid; other site
1335916004009	ABC transporter signature motif; other site
1335916004010	Walker B; other site
1335916004011	D-loop; other site
1335916004012	H-loop/switch region; other site
1335916004013	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1335916004014	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
1335916004015	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1335916004016	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916004017	dimer interface [polypeptide binding]; other site
1335916004018	conserved gate region; other site
1335916004019	putative PBP binding loops; other site
1335916004020	ABC-ATPase subunit interface; other site
1335916004021	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
1335916004022	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916004023	dimer interface [polypeptide binding]; other site
1335916004024	conserved gate region; other site
1335916004025	putative PBP binding loops; other site
1335916004026	ABC-ATPase subunit interface; other site
1335916004027	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1335916004028	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1335916004029	peptide binding site [polypeptide binding]; other site
1335916004030	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
1335916004031	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1335916004032	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1335916004033	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1335916004034	gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional; Region: puuD; PRK11366
1335916004035	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1335916004036	catalytic triad [active]
1335916004037	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1335916004038	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1335916004039	non-specific DNA binding site [nucleotide binding]; other site
1335916004040	salt bridge; other site
1335916004041	sequence-specific DNA binding site [nucleotide binding]; other site
1335916004042	Cupin domain; Region: Cupin_2; pfam07883
1335916004043	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1335916004044	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1335916004045	4-aminobutyrate transaminase; Provisional; Region: PRK09792
1335916004046	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1335916004047	inhibitor-cofactor binding pocket; inhibition site
1335916004048	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916004049	catalytic residue [active]
1335916004050	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
1335916004051	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916004052	Walker A motif; other site
1335916004053	ATP binding site [chemical binding]; other site
1335916004054	Walker B motif; other site
1335916004055	arginine finger; other site
1335916004056	phage shock protein PspA; Provisional; Region: PRK10698
1335916004057	phage shock protein B; Provisional; Region: pspB; PRK09458
1335916004058	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
1335916004059	phage shock protein C; Region: phageshock_pspC; TIGR02978
1335916004060	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
1335916004061	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1335916004062	active site residue [active]
1335916004063	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
1335916004064	sucrose phosphorylase; Provisional; Region: PRK13840
1335916004065	active site
1335916004066	homodimer interface [polypeptide binding]; other site
1335916004067	catalytic site [active]
1335916004068	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1335916004069	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1335916004070	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916004071	dimer interface [polypeptide binding]; other site
1335916004072	conserved gate region; other site
1335916004073	putative PBP binding loops; other site
1335916004074	ABC-ATPase subunit interface; other site
1335916004075	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1335916004076	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916004077	dimer interface [polypeptide binding]; other site
1335916004078	conserved gate region; other site
1335916004079	putative PBP binding loops; other site
1335916004080	ABC-ATPase subunit interface; other site
1335916004081	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1335916004082	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
1335916004083	putative NAD(P) binding site [chemical binding]; other site
1335916004084	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1335916004085	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1335916004086	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1335916004087	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1335916004088	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
1335916004089	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
1335916004090	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
1335916004091	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
1335916004092	beta-phosphoglucomutase; Region: bPGM; TIGR01990
1335916004093	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916004094	motif II; other site
1335916004095	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
1335916004096	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1335916004097	Walker A/P-loop; other site
1335916004098	ATP binding site [chemical binding]; other site
1335916004099	Q-loop/lid; other site
1335916004100	ABC transporter signature motif; other site
1335916004101	Walker B; other site
1335916004102	D-loop; other site
1335916004103	H-loop/switch region; other site
1335916004104	TOBE domain; Region: TOBE_2; pfam08402
1335916004105	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
1335916004106	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1335916004107	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1335916004108	DNA binding site [nucleotide binding]
1335916004109	domain linker motif; other site
1335916004110	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
1335916004111	putative dimerization interface [polypeptide binding]; other site
1335916004112	putative ligand binding site [chemical binding]; other site
1335916004113	Predicted ATPase [General function prediction only]; Region: COG3106
1335916004114	Predicted membrane protein [Function unknown]; Region: COG3768
1335916004115	TIGR01620 family protein; Region: hyp_HI0043
1335916004116	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1335916004117	dimer interface [polypeptide binding]; other site
1335916004118	catalytic triad [active]
1335916004119	peroxidatic and resolving cysteines [active]
1335916004120	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
1335916004121	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1335916004122	active site
1335916004123	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
1335916004124	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
1335916004125	putative active site [active]
1335916004126	Zn binding site [ion binding]; other site
1335916004127	atypical (a) SDRs, subgroup 6; Region: SDR_a6; cd05267
1335916004128	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1335916004129	putative NAD(P) binding site [chemical binding]; other site
1335916004130	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1335916004131	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1335916004132	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1335916004133	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1335916004134	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916004135	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1335916004136	putative effector binding pocket; other site
1335916004137	putative dimerization interface [polypeptide binding]; other site
1335916004138	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1335916004139	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1335916004140	peptide binding site [polypeptide binding]; other site
1335916004141	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1335916004142	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1335916004143	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
1335916004144	universal stress protein UspE; Provisional; Region: PRK11175
1335916004145	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1335916004146	Ligand Binding Site [chemical binding]; other site
1335916004147	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1335916004148	Ligand Binding Site [chemical binding]; other site
1335916004149	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1335916004150	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1335916004151	ligand binding site [chemical binding]; other site
1335916004152	flexible hinge region; other site
1335916004153	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1335916004154	putative switch regulator; other site
1335916004155	non-specific DNA interactions [nucleotide binding]; other site
1335916004156	DNA binding site [nucleotide binding]
1335916004157	sequence specific DNA binding site [nucleotide binding]; other site
1335916004158	putative cAMP binding site [chemical binding]; other site
1335916004159	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
1335916004160	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1335916004161	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1335916004162	DNA binding site [nucleotide binding]
1335916004163	active site
1335916004164	putative aminobenzoyl-glutamate transporter; Provisional; Region: abgT; PRK11339
1335916004165	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
1335916004166	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
1335916004167	amidohydrolase; Region: amidohydrolases; TIGR01891
1335916004168	putative metal binding site [ion binding]; other site
1335916004169	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
1335916004170	amidohydrolase; Region: amidohydrolases; TIGR01891
1335916004171	putative metal binding site [ion binding]; other site
1335916004172	dimer interface [polypeptide binding]; other site
1335916004173	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
1335916004174	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916004175	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
1335916004176	putative substrate binding pocket [chemical binding]; other site
1335916004177	putative dimerization interface [polypeptide binding]; other site
1335916004178	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
1335916004179	Smr domain; Region: Smr; pfam01713
1335916004180	PAS domain S-box; Region: sensory_box; TIGR00229
1335916004181	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1335916004182	putative active site [active]
1335916004183	heme pocket [chemical binding]; other site
1335916004184	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1335916004185	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1335916004186	metal binding site [ion binding]; metal-binding site
1335916004187	active site
1335916004188	I-site; other site
1335916004189	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1335916004190	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
1335916004191	Cl binding site [ion binding]; other site
1335916004192	oligomer interface [polypeptide binding]; other site
1335916004193	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1335916004194	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1335916004195	ATP binding site [chemical binding]; other site
1335916004196	Mg++ binding site [ion binding]; other site
1335916004197	motif III; other site
1335916004198	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1335916004199	nucleotide binding region [chemical binding]; other site
1335916004200	ATP-binding site [chemical binding]; other site
1335916004201	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
1335916004202	putative RNA binding site [nucleotide binding]; other site
1335916004203	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1335916004204	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1335916004205	Ligand Binding Site [chemical binding]; other site
1335916004206	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
1335916004207	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1335916004208	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
1335916004209	Int/Topo IB signature motif; other site
1335916004210	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
1335916004211	hypothetical protein; Provisional; Region: PRK09750
1335916004212	exonuclease VIII; Reviewed; Region: PRK09709
1335916004213	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
1335916004214	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
1335916004215	hypothetical protein; Reviewed; Region: PRK09790
1335916004216	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
1335916004217	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
1335916004218	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1335916004219	non-specific DNA binding site [nucleotide binding]; other site
1335916004220	salt bridge; other site
1335916004221	transcriptional repressor DicA; Reviewed; Region: PRK09706
1335916004222	sequence-specific DNA binding site [nucleotide binding]; other site
1335916004223	Helix-turn-helix domain; Region: HTH_17; cl17695
1335916004224	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
1335916004225	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3756
1335916004226	primosomal protein DnaI; Provisional; Region: PRK02854
1335916004227	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
1335916004228	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
1335916004229	Uncharacterized conserved protein [Function unknown]; Region: COG4938
1335916004230	Protein of unknown function (DUF3696); Region: DUF3696; pfam12476
1335916004231	Hok/gef family; Region: HOK_GEF; pfam01848
1335916004232	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1335916004233	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
1335916004234	Protein of unknown function (DUF1133); Region: DUF1133; pfam06576
1335916004235	Protein of unknown function (DUF754); Region: DUF754; pfam05449
1335916004236	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
1335916004237	Terminase small subunit; Region: Terminase_2; cl01513
1335916004238	phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555
1335916004239	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
1335916004240	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1335916004241	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1335916004242	catalytic residue [active]
1335916004243	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
1335916004244	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1335916004245	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
1335916004246	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1335916004247	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
1335916004248	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1335916004249	Ligand Binding Site [chemical binding]; other site
1335916004250	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1335916004251	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1335916004252	trimer interface [polypeptide binding]; other site
1335916004253	eyelet of channel; other site
1335916004254	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1335916004255	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1335916004256	heat-inducible protein; Provisional; Region: PRK10449
1335916004257	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1335916004258	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1335916004259	beta-galactosidase; Region: BGL; TIGR03356
1335916004260	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
1335916004261	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1335916004262	active site turn [active]
1335916004263	phosphorylation site [posttranslational modification]
1335916004264	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1335916004265	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1335916004266	HPr interaction site; other site
1335916004267	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1335916004268	active site
1335916004269	phosphorylation site [posttranslational modification]
1335916004270	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1335916004271	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1335916004272	hypothetical protein; Provisional; Region: PRK10695
1335916004273	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1335916004274	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
1335916004275	DNA-binding transcriptional activator FeaR; Provisional; Region: PRK09685
1335916004276	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916004277	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1335916004278	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1335916004279	NAD(P) binding site [chemical binding]; other site
1335916004280	catalytic residues [active]
1335916004281	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Provisional; Region: PRK11563
1335916004282	N-terminal domain of the monoamine oxidase C dehydratase; Region: ALDH_MaoC-N; cd07128
1335916004283	substrate binding site [chemical binding]; other site
1335916004284	dimer interface [polypeptide binding]; other site
1335916004285	NADP binding site [chemical binding]; other site
1335916004286	catalytic residues [active]
1335916004287	MaoC_C  The C-terminal hot dog fold of the MaoC (monoamine oxidase C) dehydratase regulatory protein. Orthologs of MaoC include PaaZ [Escherichia coli] and PaaN [Pseudomonas putida], which are putative ring-opening enzymes involved in phenylacetic acid...; Region: MaoC_C; cd03452
1335916004288	substrate binding site [chemical binding]; other site
1335916004289	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
1335916004290	phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156
1335916004291	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
1335916004292	phenylacetate-CoA oxygenase, PaaI subunit; Region: PA_CoA_Oxy3; TIGR02158
1335916004293	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
1335916004294	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
1335916004295	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
1335916004296	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
1335916004297	FAD binding pocket [chemical binding]; other site
1335916004298	FAD binding motif [chemical binding]; other site
1335916004299	phosphate binding motif [ion binding]; other site
1335916004300	beta-alpha-beta structure motif; other site
1335916004301	NAD(p) ribose binding residues [chemical binding]; other site
1335916004302	NAD binding pocket [chemical binding]; other site
1335916004303	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
1335916004304	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1335916004305	catalytic loop [active]
1335916004306	iron binding site [ion binding]; other site
1335916004307	enoyl-CoA hydratase-isomerase; Provisional; Region: PRK09674
1335916004308	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1335916004309	substrate binding site [chemical binding]; other site
1335916004310	oxyanion hole (OAH) forming residues; other site
1335916004311	trimer interface [polypeptide binding]; other site
1335916004312	enoyl-CoA hydratase; Provisional; Region: PRK08140
1335916004313	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1335916004314	substrate binding site [chemical binding]; other site
1335916004315	oxyanion hole (OAH) forming residues; other site
1335916004316	trimer interface [polypeptide binding]; other site
1335916004317	3-hydroxyacyl-CoA dehydrogenase PaaC; Region: PaaC-3OHAcCoADH; TIGR02279
1335916004318	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1335916004319	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1335916004320	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1335916004321	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1335916004322	CoenzymeA binding site [chemical binding]; other site
1335916004323	subunit interaction site [polypeptide binding]; other site
1335916004324	PHB binding site; other site
1335916004325	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
1335916004326	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1335916004327	dimer interface [polypeptide binding]; other site
1335916004328	active site
1335916004329	Phenylacetate-CoA ligase (also known as PaaK); Region: PaaK; cd05913
1335916004330	phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155
1335916004331	active site
1335916004332	AMP binding site [chemical binding]; other site
1335916004333	homodimer interface [polypeptide binding]; other site
1335916004334	acyl-activating enzyme (AAE) consensus motif; other site
1335916004335	CoA binding site [chemical binding]; other site
1335916004336	PaaX-like protein; Region: PaaX; pfam07848
1335916004337	phenylacetic acid degradation operon negative regulatory protein PaaX; Region: PaaX_trns_reg; TIGR02277
1335916004338	PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223
1335916004339	phenylacetic acid degradation protein PaaY; Region: PaaY; TIGR02287
1335916004340	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
1335916004341	putative trimer interface [polypeptide binding]; other site
1335916004342	putative metal binding site [ion binding]; other site
1335916004343	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1335916004344	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1335916004345	active site
1335916004346	catalytic tetrad [active]
1335916004347	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1335916004348	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
1335916004349	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
1335916004350	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
1335916004351	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1335916004352	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1335916004353	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1335916004354	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916004355	S-adenosylmethionine binding site [chemical binding]; other site
1335916004356	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
1335916004357	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1335916004358	active site
1335916004359	Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; Region: DSPc; cd00127
1335916004360	active site
1335916004361	catalytic residues [active]
1335916004362	azoreductase; Reviewed; Region: PRK00170
1335916004363	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1335916004364	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1335916004365	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1335916004366	ATP binding site [chemical binding]; other site
1335916004367	putative Mg++ binding site [ion binding]; other site
1335916004368	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1335916004369	nucleotide binding region [chemical binding]; other site
1335916004370	ATP-binding site [chemical binding]; other site
1335916004371	Helicase associated domain (HA2); Region: HA2; pfam04408
1335916004372	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1335916004373	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1335916004374	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1335916004375	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1335916004376	putative active site [active]
1335916004377	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
1335916004378	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1335916004379	NAD binding site [chemical binding]; other site
1335916004380	catalytic residues [active]
1335916004381	substrate binding site [chemical binding]; other site
1335916004382	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
1335916004383	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1335916004384	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1335916004385	cytochrome b561; Provisional; Region: PRK11513
1335916004386	hypothetical protein; Provisional; Region: PRK10040
1335916004387	small toxic polypeptide; Provisional; Region: PRK09738
1335916004388	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1335916004389	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1335916004390	dimer interface [polypeptide binding]; other site
1335916004391	ligand binding site [chemical binding]; other site
1335916004392	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1335916004393	dimerization interface [polypeptide binding]; other site
1335916004394	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1335916004395	dimer interface [polypeptide binding]; other site
1335916004396	putative CheW interface [polypeptide binding]; other site
1335916004397	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1335916004398	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916004399	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1335916004400	dimerization interface [polypeptide binding]; other site
1335916004401	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1335916004402	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1335916004403	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
1335916004404	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
1335916004405	hypothetical protein; Provisional; Region: PRK11415
1335916004406	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1335916004407	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1335916004408	Coenzyme A binding pocket [chemical binding]; other site
1335916004409	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1335916004410	putative trimer interface [polypeptide binding]; other site
1335916004411	putative CoA binding site [chemical binding]; other site
1335916004412	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
1335916004413	putative trimer interface [polypeptide binding]; other site
1335916004414	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1335916004415	putative CoA binding site [chemical binding]; other site
1335916004416	putative trimer interface [polypeptide binding]; other site
1335916004417	putative CoA binding site [chemical binding]; other site
1335916004418	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
1335916004419	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
1335916004420	gating phenylalanine in ion channel; other site
1335916004421	tellurite resistance protein TehB; Provisional; Region: PRK11207
1335916004422	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916004423	S-adenosylmethionine binding site [chemical binding]; other site
1335916004424	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
1335916004425	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1335916004426	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1335916004427	Probable transposase; Region: OrfB_IS605; pfam01385
1335916004428	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1335916004429	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
1335916004430	benzoate transporter; Region: benE; TIGR00843
1335916004431	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1335916004432	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1335916004433	non-specific DNA binding site [nucleotide binding]; other site
1335916004434	salt bridge; other site
1335916004435	sequence-specific DNA binding site [nucleotide binding]; other site
1335916004436	Cupin domain; Region: Cupin_2; pfam07883
1335916004437	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1335916004438	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1335916004439	Peptidase family U32; Region: Peptidase_U32; pfam01136
1335916004440	Collagenase; Region: DUF3656; pfam12392
1335916004441	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
1335916004442	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
1335916004443	Helix-turn-helix; Region: HTH_3; pfam01381
1335916004444	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1335916004445	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916004446	DNA-binding site [nucleotide binding]; DNA binding site
1335916004447	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1335916004448	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916004449	homodimer interface [polypeptide binding]; other site
1335916004450	catalytic residue [active]
1335916004451	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1335916004452	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1335916004453	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1335916004454	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916004455	Walker A/P-loop; other site
1335916004456	ATP binding site [chemical binding]; other site
1335916004457	Q-loop/lid; other site
1335916004458	ABC transporter signature motif; other site
1335916004459	Walker B; other site
1335916004460	D-loop; other site
1335916004461	H-loop/switch region; other site
1335916004462	TOBE domain; Region: TOBE_2; pfam08402
1335916004463	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916004464	dimer interface [polypeptide binding]; other site
1335916004465	conserved gate region; other site
1335916004466	putative PBP binding loops; other site
1335916004467	ABC-ATPase subunit interface; other site
1335916004468	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1335916004469	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916004470	ABC-ATPase subunit interface; other site
1335916004471	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
1335916004472	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
1335916004473	tetrameric interface [polypeptide binding]; other site
1335916004474	NAD binding site [chemical binding]; other site
1335916004475	catalytic residues [active]
1335916004476	substrate binding site [chemical binding]; other site
1335916004477	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1335916004478	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
1335916004479	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1335916004480	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1335916004481	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1335916004482	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
1335916004483	Prostaglandin dehydrogenases; Region: PGDH; cd05288
1335916004484	NAD(P) binding site [chemical binding]; other site
1335916004485	substrate binding site [chemical binding]; other site
1335916004486	dimer interface [polypeptide binding]; other site
1335916004487	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
1335916004488	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916004489	DNA-binding site [nucleotide binding]; DNA binding site
1335916004490	FCD domain; Region: FCD; pfam07729
1335916004491	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1335916004492	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1335916004493	N-terminal plug; other site
1335916004494	ligand-binding site [chemical binding]; other site
1335916004495	PQQ-like domain; Region: PQQ_2; pfam13360
1335916004496	L-asparagine permease; Provisional; Region: PRK15049
1335916004497	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1335916004498	C-terminal domain interface [polypeptide binding]; other site
1335916004499	GSH binding site (G-site) [chemical binding]; other site
1335916004500	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1335916004501	dimer interface [polypeptide binding]; other site
1335916004502	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1335916004503	dimer interface [polypeptide binding]; other site
1335916004504	N-terminal domain interface [polypeptide binding]; other site
1335916004505	substrate binding pocket (H-site) [chemical binding]; other site
1335916004506	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1335916004507	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1335916004508	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1335916004509	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1335916004510	PAAR motif; Region: PAAR_motif; cl15808
1335916004511	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1335916004512	RHS Repeat; Region: RHS_repeat; pfam05593
1335916004513	RHS Repeat; Region: RHS_repeat; pfam05593
1335916004514	RHS Repeat; Region: RHS_repeat; pfam05593
1335916004515	RHS Repeat; Region: RHS_repeat; pfam05593
1335916004516	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1335916004517	RHS Repeat; Region: RHS_repeat; pfam05593
1335916004518	RHS Repeat; Region: RHS_repeat; pfam05593
1335916004519	RHS protein; Region: RHS; pfam03527
1335916004520	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1335916004521	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1335916004522	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916004523	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1335916004524	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1335916004525	4-oxalocrotonate tautomerase; Provisional; Region: PRK01271
1335916004526	active site 1 [active]
1335916004527	dimer interface [polypeptide binding]; other site
1335916004528	hexamer interface [polypeptide binding]; other site
1335916004529	active site 2 [active]
1335916004530	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1335916004531	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
1335916004532	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1335916004533	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
1335916004534	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1335916004535	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
1335916004536	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1335916004537	[4Fe-4S] binding site [ion binding]; other site
1335916004538	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1335916004539	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1335916004540	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1335916004541	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1335916004542	molybdopterin cofactor binding site; other site
1335916004543	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1335916004544	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
1335916004545	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1335916004546	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1335916004547	aromatic amino acid exporter; Provisional; Region: PRK11689
1335916004548	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1335916004549	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1335916004550	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1335916004551	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1335916004552	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1335916004553	molybdopterin cofactor binding site; other site
1335916004554	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1335916004555	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1335916004556	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
1335916004557	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1335916004558	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
1335916004559	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1335916004560	non-specific DNA binding site [nucleotide binding]; other site
1335916004561	salt bridge; other site
1335916004562	sequence-specific DNA binding site [nucleotide binding]; other site
1335916004563	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
1335916004564	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1335916004565	NAD binding site [chemical binding]; other site
1335916004566	substrate binding site [chemical binding]; other site
1335916004567	catalytic Zn binding site [ion binding]; other site
1335916004568	tetramer interface [polypeptide binding]; other site
1335916004569	structural Zn binding site [ion binding]; other site
1335916004570	malate dehydrogenase; Provisional; Region: PRK13529
1335916004571	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1335916004572	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1335916004573	NAD(P) binding site [chemical binding]; other site
1335916004574	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
1335916004575	Putative biofilm-dependent modulation protein; Region: BDM; cl11581
1335916004576	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
1335916004577	D-ala-D-ala transporter subunit; Provisional; Region: PRK09881
1335916004578	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1335916004579	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916004580	dimer interface [polypeptide binding]; other site
1335916004581	conserved gate region; other site
1335916004582	putative PBP binding loops; other site
1335916004583	ABC-ATPase subunit interface; other site
1335916004584	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1335916004585	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916004586	dimer interface [polypeptide binding]; other site
1335916004587	conserved gate region; other site
1335916004588	putative PBP binding loops; other site
1335916004589	ABC-ATPase subunit interface; other site
1335916004590	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1335916004591	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1335916004592	cyclic-di-GMP phosphodiesterase; Provisional; Region: PRK11359
1335916004593	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1335916004594	putative active site [active]
1335916004595	heme pocket [chemical binding]; other site
1335916004596	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1335916004597	putative active site [active]
1335916004598	heme pocket [chemical binding]; other site
1335916004599	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1335916004600	metal binding site [ion binding]; metal-binding site
1335916004601	active site
1335916004602	I-site; other site
1335916004603	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1335916004604	Globin domain present in Globin-Coupled-Sensors (GCS). These domains detect changes in intracellular concentrations of oxygen, carbon monoxyde, or nitrous oxide,  which result in aerotaxis and/or gene regulation. One subgroup, the HemATs, are aerotactic...; Region: sensor_globin; cd01068
1335916004605	heme-binding site [chemical binding]; other site
1335916004606	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1335916004607	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1335916004608	metal binding site [ion binding]; metal-binding site
1335916004609	active site
1335916004610	I-site; other site
1335916004611	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
1335916004612	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
1335916004613	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
1335916004614	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
1335916004615	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916004616	catalytic residue [active]
1335916004617	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1335916004618	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1335916004619	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1335916004620	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1335916004621	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1335916004622	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1335916004623	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1335916004624	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
1335916004625	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
1335916004626	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
1335916004627	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1335916004628	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916004629	FeS/SAM binding site; other site
1335916004630	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1335916004631	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1335916004632	Sulfatase; Region: Sulfatase; cl17466
1335916004633	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1335916004634	Sulfatase; Region: Sulfatase; cl17466
1335916004635	transcriptional regulator YdeO; Provisional; Region: PRK09940
1335916004636	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916004637	putative oxidoreductase; Provisional; Region: PRK09939
1335916004638	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
1335916004639	putative molybdopterin cofactor binding site [chemical binding]; other site
1335916004640	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
1335916004641	putative molybdopterin cofactor binding site; other site
1335916004642	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
1335916004643	mannosyl binding site [chemical binding]; other site
1335916004644	Fimbrial protein; Region: Fimbrial; pfam00419
1335916004645	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1335916004646	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1335916004647	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1335916004648	PapC N-terminal domain; Region: PapC_N; pfam13954
1335916004649	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1335916004650	PapC C-terminal domain; Region: PapC_C; pfam13953
1335916004651	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1335916004652	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1335916004653	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1335916004654	Fimbrial protein; Region: Fimbrial; cl01416
1335916004655	HipA N-terminal domain; Region: Couple_hipA; pfam13657
1335916004656	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
1335916004657	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1335916004658	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1335916004659	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1335916004660	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1335916004661	non-specific DNA binding site [nucleotide binding]; other site
1335916004662	salt bridge; other site
1335916004663	sequence-specific DNA binding site [nucleotide binding]; other site
1335916004664	putative lipoprotein/autotransporter domain-containing protein; Provisional; Region: PRK14849
1335916004665	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1335916004666	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1335916004667	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916004668	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
1335916004669	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1335916004670	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1335916004671	trimer interface; other site
1335916004672	sugar binding site [chemical binding]; other site
1335916004673	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1335916004674	active site
1335916004675	methionine cluster; other site
1335916004676	phosphorylation site [posttranslational modification]
1335916004677	metal binding site [ion binding]; metal-binding site
1335916004678	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1335916004679	active site
1335916004680	P-loop; other site
1335916004681	phosphorylation site [posttranslational modification]
1335916004682	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1335916004683	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916004684	DNA-binding site [nucleotide binding]; DNA binding site
1335916004685	UTRA domain; Region: UTRA; pfam07702
1335916004686	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
1335916004687	EamA-like transporter family; Region: EamA; pfam00892
1335916004688	EamA-like transporter family; Region: EamA; pfam00892
1335916004689	putative transporter; Provisional; Region: PRK10054
1335916004690	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916004691	putative substrate translocation pore; other site
1335916004692	diguanylate cyclase; Provisional; Region: PRK09894
1335916004693	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
1335916004694	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1335916004695	metal binding site [ion binding]; metal-binding site
1335916004696	active site
1335916004697	I-site; other site
1335916004698	hypothetical protein; Provisional; Region: PRK10053
1335916004699	hypothetical protein; Validated; Region: PRK03657
1335916004700	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
1335916004701	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1335916004702	active site
1335916004703	Zn binding site [ion binding]; other site
1335916004704	malonic semialdehyde reductase; Provisional; Region: PRK10538
1335916004705	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1335916004706	putative NAD(P) binding site [chemical binding]; other site
1335916004707	homodimer interface [polypeptide binding]; other site
1335916004708	homotetramer interface [polypeptide binding]; other site
1335916004709	active site
1335916004710	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1335916004711	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916004712	DNA-binding site [nucleotide binding]; DNA binding site
1335916004713	FCD domain; Region: FCD; pfam07729
1335916004714	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
1335916004715	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1335916004716	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1335916004717	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1335916004718	metabolite-proton symporter; Region: 2A0106; TIGR00883
1335916004719	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916004720	putative substrate translocation pore; other site
1335916004721	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916004722	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1335916004723	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1335916004724	Presynaptic Site I dimer interface [polypeptide binding]; other site
1335916004725	catalytic residues [active]
1335916004726	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1335916004727	Synaptic Flat tetramer interface [polypeptide binding]; other site
1335916004728	Synaptic Site I dimer interface [polypeptide binding]; other site
1335916004729	DNA binding site [nucleotide binding]
1335916004730	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1335916004731	DNA-binding interface [nucleotide binding]; DNA binding site
1335916004732	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1335916004733	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
1335916004734	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1335916004735	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1335916004736	Phage Tail Collar Domain; Region: Collar; pfam07484
1335916004737	Phage-related protein, tail component [Function unknown]; Region: COG4733
1335916004738	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1335916004739	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1335916004740	Interdomain contacts; other site
1335916004741	Cytokine receptor motif; other site
1335916004742	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1335916004743	Fibronectin type III protein; Region: DUF3672; pfam12421
1335916004744	Phage-related protein, tail component [Function unknown]; Region: COG4723
1335916004745	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1335916004746	MPN+ (JAMM) motif; other site
1335916004747	Zinc-binding site [ion binding]; other site
1335916004748	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1335916004749	NlpC/P60 family; Region: NLPC_P60; cl17555
1335916004750	Phage-related protein [Function unknown]; Region: gp18; COG4672
1335916004751	Phage-related protein [Function unknown]; Region: COG4718
1335916004752	Phage-related minor tail protein [Function unknown]; Region: COG5281
1335916004753	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1335916004754	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1335916004755	Minor tail protein T; Region: Phage_tail_T; pfam06223
1335916004756	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
1335916004757	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1335916004758	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
1335916004759	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1335916004760	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1335916004761	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
1335916004762	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
1335916004763	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
1335916004764	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1335916004765	tandem repeat interface [polypeptide binding]; other site
1335916004766	oligomer interface [polypeptide binding]; other site
1335916004767	active site residues [active]
1335916004768	gpW; Region: gpW; pfam02831
1335916004769	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1335916004770	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
1335916004771	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
1335916004772	GnsA/GnsB family; Region: GnsAB; pfam08178
1335916004773	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1335916004774	DNA-binding site [nucleotide binding]; DNA binding site
1335916004775	RNA-binding motif; other site
1335916004776	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
1335916004777	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1335916004778	catalytic residues [active]
1335916004779	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
1335916004780	Lysis protein S; Region: Lysis_S; pfam04971
1335916004781	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1335916004782	DNA-binding site [nucleotide binding]; DNA binding site
1335916004783	RNA-binding motif; other site
1335916004784	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1335916004785	DNA-binding site [nucleotide binding]; DNA binding site
1335916004786	RNA-binding motif; other site
1335916004787	Antitermination protein; Region: Antiterm; pfam03589
1335916004788	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1335916004789	DnaJ central domain; Region: DnaJ_CXXCXGXG; pfam00684
1335916004790	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1335916004791	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1335916004792	Hok/gef family; Region: HOK_GEF; pfam01848
1335916004793	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1335916004794	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
1335916004795	Homeodomain-like domain; Region: HTH_23; pfam13384
1335916004796	Winged helix-turn helix; Region: HTH_29; pfam13551
1335916004797	Homeodomain-like domain; Region: HTH_32; pfam13565
1335916004798	Integrase core domain; Region: rve; pfam00665
1335916004799	Integrase core domain; Region: rve_3; cl15866
1335916004800	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
1335916004801	primosomal protein DnaI; Provisional; Region: PRK02854
1335916004802	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
1335916004803	DNA-binding transcriptional regulator DicC; Provisional; Region: PRK09744
1335916004804	transcriptional repressor DicA; Reviewed; Region: PRK09706
1335916004805	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1335916004806	non-specific DNA binding site [nucleotide binding]; other site
1335916004807	salt bridge; other site
1335916004808	sequence-specific DNA binding site [nucleotide binding]; other site
1335916004809	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
1335916004810	DicB protein; Region: DicB; pfam05358
1335916004811	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1335916004812	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1335916004813	active site
1335916004814	catalytic site [active]
1335916004815	substrate binding site [chemical binding]; other site
1335916004816	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
1335916004817	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
1335916004818	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1335916004819	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
1335916004820	Int/Topo IB signature motif; other site
1335916004821	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916004822	putative oxidoreductase; Provisional; Region: PRK10083
1335916004823	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1335916004824	putative NAD(P) binding site [chemical binding]; other site
1335916004825	catalytic Zn binding site [ion binding]; other site
1335916004826	structural Zn binding site [ion binding]; other site
1335916004827	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1335916004828	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
1335916004829	putative active site pocket [active]
1335916004830	putative metal binding site [ion binding]; other site
1335916004831	hypothetical protein; Provisional; Region: PRK02237
1335916004832	hypothetical protein; Provisional; Region: PRK13659
1335916004833	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
1335916004834	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1335916004835	Coenzyme A binding pocket [chemical binding]; other site
1335916004836	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
1335916004837	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
1335916004838	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1335916004839	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1335916004840	putative [Fe4-S4] binding site [ion binding]; other site
1335916004841	putative molybdopterin cofactor binding site [chemical binding]; other site
1335916004842	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1335916004843	putative molybdopterin cofactor binding site; other site
1335916004844	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1335916004845	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1335916004846	putative [Fe4-S4] binding site [ion binding]; other site
1335916004847	putative molybdopterin cofactor binding site [chemical binding]; other site
1335916004848	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1335916004849	putative molybdopterin cofactor binding site; other site
1335916004850	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1335916004851	4Fe-4S binding domain; Region: Fer4; cl02805
1335916004852	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
1335916004853	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
1335916004854	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1335916004855	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1335916004856	Cl- selectivity filter; other site
1335916004857	Cl- binding residues [ion binding]; other site
1335916004858	pore gating glutamate residue; other site
1335916004859	dimer interface [polypeptide binding]; other site
1335916004860	putative dithiobiotin synthetase; Provisional; Region: PRK12374
1335916004861	AAA domain; Region: AAA_26; pfam13500
1335916004862	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1335916004863	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1335916004864	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1335916004865	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1335916004866	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1335916004867	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916004868	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1335916004869	dimerization interface [polypeptide binding]; other site
1335916004870	substrate binding pocket [chemical binding]; other site
1335916004871	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1335916004872	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916004873	putative substrate translocation pore; other site
1335916004874	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
1335916004875	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
1335916004876	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
1335916004877	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
1335916004878	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1335916004879	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1335916004880	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1335916004881	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1335916004882	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1335916004883	ligand binding site [chemical binding]; other site
1335916004884	homodimer interface [polypeptide binding]; other site
1335916004885	NAD(P) binding site [chemical binding]; other site
1335916004886	trimer interface B [polypeptide binding]; other site
1335916004887	trimer interface A [polypeptide binding]; other site
1335916004888	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1335916004889	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1335916004890	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1335916004891	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1335916004892	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
1335916004893	Spore germination protein; Region: Spore_permease; cl17796
1335916004894	dihydromonapterin reductase; Provisional; Region: PRK06483
1335916004895	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
1335916004896	NADP binding site [chemical binding]; other site
1335916004897	substrate binding pocket [chemical binding]; other site
1335916004898	active site
1335916004899	GlpM protein; Region: GlpM; pfam06942
1335916004900	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
1335916004901	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916004902	active site
1335916004903	phosphorylation site [posttranslational modification]
1335916004904	intermolecular recognition site; other site
1335916004905	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1335916004906	DNA binding site [nucleotide binding]
1335916004907	sensor protein RstB; Provisional; Region: PRK10604
1335916004908	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1335916004909	dimerization interface [polypeptide binding]; other site
1335916004910	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916004911	dimer interface [polypeptide binding]; other site
1335916004912	phosphorylation site [posttranslational modification]
1335916004913	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916004914	ATP binding site [chemical binding]; other site
1335916004915	Mg2+ binding site [ion binding]; other site
1335916004916	G-X-G motif; other site
1335916004917	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
1335916004918	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1335916004919	Class II fumarases; Region: Fumarase_classII; cd01362
1335916004920	active site
1335916004921	tetramer interface [polypeptide binding]; other site
1335916004922	fumarate hydratase; Provisional; Region: PRK15389
1335916004923	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1335916004924	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1335916004925	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
1335916004926	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1335916004927	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
1335916004928	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1335916004929	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
1335916004930	putative outer membrane porin protein; Provisional; Region: PRK11379
1335916004931	glucuronide transporter; Provisional; Region: PRK09848
1335916004932	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1335916004933	beta-D-glucuronidase; Provisional; Region: PRK10150
1335916004934	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1335916004935	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1335916004936	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1335916004937	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1335916004938	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1335916004939	7-alpha-hydroxysteroid dehydrogenase; Validated; Region: PRK06113
1335916004940	7 alpha-hydroxysteroid dehydrogenase (7 alpha-HSDH), classical (c) SDRs; Region: 7_alpha_HSDH_SDR_c; cd05365
1335916004941	NAD binding site [chemical binding]; other site
1335916004942	substrate binding site [chemical binding]; other site
1335916004943	homotetramer interface [polypeptide binding]; other site
1335916004944	homodimer interface [polypeptide binding]; other site
1335916004945	active site
1335916004946	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916004947	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
1335916004948	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1335916004949	DNA binding site [nucleotide binding]
1335916004950	domain linker motif; other site
1335916004951	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
1335916004952	putative dimerization interface [polypeptide binding]; other site
1335916004953	putative ligand binding site [chemical binding]; other site
1335916004954	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
1335916004955	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1335916004956	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1335916004957	active site turn [active]
1335916004958	phosphorylation site [posttranslational modification]
1335916004959	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1335916004960	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1335916004961	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916004962	homodimer interface [polypeptide binding]; other site
1335916004963	catalytic residue [active]
1335916004964	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1335916004965	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
1335916004966	active site
1335916004967	purine riboside binding site [chemical binding]; other site
1335916004968	putative oxidoreductase; Provisional; Region: PRK11579
1335916004969	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1335916004970	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1335916004971	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
1335916004972	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1335916004973	electron transport complex protein RsxA; Provisional; Region: PRK05151
1335916004974	electron transport complex protein RnfB; Provisional; Region: PRK05113
1335916004975	Putative Fe-S cluster; Region: FeS; pfam04060
1335916004976	4Fe-4S binding domain; Region: Fer4; pfam00037
1335916004977	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
1335916004978	SLBB domain; Region: SLBB; pfam10531
1335916004979	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1335916004980	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1335916004981	electron transport complex protein RnfG; Validated; Region: PRK01908
1335916004982	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1335916004983	endonuclease III; Provisional; Region: PRK10702
1335916004984	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1335916004985	minor groove reading motif; other site
1335916004986	helix-hairpin-helix signature motif; other site
1335916004987	substrate binding pocket [chemical binding]; other site
1335916004988	active site
1335916004989	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1335916004990	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1335916004991	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916004992	putative substrate translocation pore; other site
1335916004993	POT family; Region: PTR2; pfam00854
1335916004994	glutathionine S-transferase; Provisional; Region: PRK10542
1335916004995	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1335916004996	C-terminal domain interface [polypeptide binding]; other site
1335916004997	GSH binding site (G-site) [chemical binding]; other site
1335916004998	dimer interface [polypeptide binding]; other site
1335916004999	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1335916005000	N-terminal domain interface [polypeptide binding]; other site
1335916005001	dimer interface [polypeptide binding]; other site
1335916005002	substrate binding pocket (H-site) [chemical binding]; other site
1335916005003	pyridoxamine kinase; Validated; Region: PRK05756
1335916005004	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1335916005005	dimer interface [polypeptide binding]; other site
1335916005006	pyridoxal binding site [chemical binding]; other site
1335916005007	ATP binding site [chemical binding]; other site
1335916005008	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1335916005009	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1335916005010	active site
1335916005011	HIGH motif; other site
1335916005012	dimer interface [polypeptide binding]; other site
1335916005013	KMSKS motif; other site
1335916005014	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1335916005015	RNA binding surface [nucleotide binding]; other site
1335916005016	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1335916005017	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1335916005018	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1335916005019	lysozyme inhibitor; Provisional; Region: PRK11372
1335916005020	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
1335916005021	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
1335916005022	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
1335916005023	transcriptional regulator SlyA; Provisional; Region: PRK03573
1335916005024	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1335916005025	Protein of unknown function (DUF1656); Region: DUF1656; cl11658
1335916005026	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1335916005027	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1335916005028	HlyD family secretion protein; Region: HlyD_3; pfam13437
1335916005029	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1335916005030	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1335916005031	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1335916005032	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1335916005033	E-class dimer interface [polypeptide binding]; other site
1335916005034	P-class dimer interface [polypeptide binding]; other site
1335916005035	active site
1335916005036	Cu2+ binding site [ion binding]; other site
1335916005037	Zn2+ binding site [ion binding]; other site
1335916005038	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1335916005039	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1335916005040	active site
1335916005041	catalytic tetrad [active]
1335916005042	Predicted Fe-S protein [General function prediction only]; Region: COG3313
1335916005043	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1335916005044	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1335916005045	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1335916005046	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1335916005047	FMN binding site [chemical binding]; other site
1335916005048	active site
1335916005049	substrate binding site [chemical binding]; other site
1335916005050	catalytic residue [active]
1335916005051	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1335916005052	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1335916005053	dimer interface [polypeptide binding]; other site
1335916005054	active site
1335916005055	metal binding site [ion binding]; metal-binding site
1335916005056	glutathione binding site [chemical binding]; other site
1335916005057	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1335916005058	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
1335916005059	dimer interface [polypeptide binding]; other site
1335916005060	catalytic site [active]
1335916005061	putative active site [active]
1335916005062	putative substrate binding site [chemical binding]; other site
1335916005063	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1335916005064	putative GSH binding site [chemical binding]; other site
1335916005065	catalytic residues [active]
1335916005066	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1335916005067	NlpC/P60 family; Region: NLPC_P60; pfam00877
1335916005068	superoxide dismutase; Provisional; Region: PRK10543
1335916005069	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1335916005070	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1335916005071	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916005072	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1335916005073	putative substrate translocation pore; other site
1335916005074	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1335916005075	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1335916005076	DNA binding site [nucleotide binding]
1335916005077	domain linker motif; other site
1335916005078	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1335916005079	dimerization interface [polypeptide binding]; other site
1335916005080	ligand binding site [chemical binding]; other site
1335916005081	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1335916005082	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916005083	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1335916005084	dimerization interface [polypeptide binding]; other site
1335916005085	putative transporter; Provisional; Region: PRK11043
1335916005086	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916005087	putative substrate translocation pore; other site
1335916005088	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
1335916005089	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1335916005090	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916005091	S-adenosylmethionine binding site [chemical binding]; other site
1335916005092	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1335916005093	Lumazine binding domain; Region: Lum_binding; pfam00677
1335916005094	Lumazine binding domain; Region: Lum_binding; pfam00677
1335916005095	multidrug efflux protein; Reviewed; Region: PRK01766
1335916005096	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1335916005097	cation binding site [ion binding]; other site
1335916005098	hypothetical protein; Provisional; Region: PRK09945
1335916005099	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
1335916005100	putative monooxygenase; Provisional; Region: PRK11118
1335916005101	hypothetical protein; Provisional; Region: PRK09897
1335916005102	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
1335916005103	hypothetical protein; Provisional; Region: PRK09946
1335916005104	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
1335916005105	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
1335916005106	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
1335916005107	hypothetical protein; Provisional; Region: PRK09947
1335916005108	putative oxidoreductase; Provisional; Region: PRK09849
1335916005109	Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; pfam02730
1335916005110	Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314
1335916005111	hypothetical protein; Provisional; Region: PRK09898
1335916005112	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1335916005113	hypothetical protein; Provisional; Region: PRK10292
1335916005114	pyruvate kinase; Provisional; Region: PRK09206
1335916005115	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1335916005116	domain interfaces; other site
1335916005117	active site
1335916005118	murein lipoprotein; Provisional; Region: PRK15396
1335916005119	L,D-transpeptidase; Provisional; Region: PRK10190
1335916005120	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1335916005121	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1335916005122	cysteine desufuration protein SufE; Provisional; Region: PRK09296
1335916005123	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1335916005124	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1335916005125	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1335916005126	catalytic residue [active]
1335916005127	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
1335916005128	FeS assembly protein SufD; Region: sufD; TIGR01981
1335916005129	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
1335916005130	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1335916005131	Walker A/P-loop; other site
1335916005132	ATP binding site [chemical binding]; other site
1335916005133	Q-loop/lid; other site
1335916005134	ABC transporter signature motif; other site
1335916005135	Walker B; other site
1335916005136	D-loop; other site
1335916005137	H-loop/switch region; other site
1335916005138	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1335916005139	putative ABC transporter; Region: ycf24; CHL00085
1335916005140	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
1335916005141	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1335916005142	CoenzymeA binding site [chemical binding]; other site
1335916005143	subunit interaction site [polypeptide binding]; other site
1335916005144	PHB binding site; other site
1335916005145	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1335916005146	FAD binding domain; Region: FAD_binding_4; pfam01565
1335916005147	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1335916005148	putative inner membrane protein; Provisional; Region: PRK10983
1335916005149	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1335916005150	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
1335916005151	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916005152	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1335916005153	putative substrate translocation pore; other site
1335916005154	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916005155	putative substrate translocation pore; other site
1335916005156	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
1335916005157	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1335916005158	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1335916005159	shikimate binding site; other site
1335916005160	NAD(P) binding site [chemical binding]; other site
1335916005161	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
1335916005162	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1335916005163	active site
1335916005164	catalytic residue [active]
1335916005165	dimer interface [polypeptide binding]; other site
1335916005166	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
1335916005167	Coenzyme A transferase; Region: CoA_trans; smart00882
1335916005168	Coenzyme A transferase; Region: CoA_trans; cl17247
1335916005169	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
1335916005170	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1335916005171	active site
1335916005172	Cupin domain; Region: Cupin_2; pfam07883
1335916005173	Winged helix DNA-binding domain (DUF1495); Region: DUF1495; cl01336
1335916005174	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1335916005175	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916005176	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1335916005177	Ligand binding site [chemical binding]; other site
1335916005178	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1335916005179	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
1335916005180	Electron transfer flavoprotein domain; Region: ETF; smart00893
1335916005181	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1335916005182	oxidoreductase; Provisional; Region: PRK10015
1335916005183	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1335916005184	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
1335916005185	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
1335916005186	acyl-activating enzyme (AAE) consensus motif; other site
1335916005187	putative AMP binding site [chemical binding]; other site
1335916005188	putative active site [active]
1335916005189	putative CoA binding site [chemical binding]; other site
1335916005190	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1335916005191	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1335916005192	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1335916005193	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1335916005194	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1335916005195	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1335916005196	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1335916005197	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
1335916005198	Uncharacterized conserved protein [Function unknown]; Region: COG0397
1335916005199	hypothetical protein; Validated; Region: PRK00029
1335916005200	NlpC/P60 family; Region: NLPC_P60; pfam00877
1335916005201	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
1335916005202	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1335916005203	Walker A/P-loop; other site
1335916005204	ATP binding site [chemical binding]; other site
1335916005205	Q-loop/lid; other site
1335916005206	ABC transporter signature motif; other site
1335916005207	Walker B; other site
1335916005208	D-loop; other site
1335916005209	H-loop/switch region; other site
1335916005210	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1335916005211	catalytic residues [active]
1335916005212	dimer interface [polypeptide binding]; other site
1335916005213	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1335916005214	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1335916005215	ABC-ATPase subunit  interface; other site
1335916005216	dimer interface [polypeptide binding]; other site
1335916005217	putative PBP binding regions; other site
1335916005218	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1335916005219	IHF dimer interface [polypeptide binding]; other site
1335916005220	IHF - DNA interface [nucleotide binding]; other site
1335916005221	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1335916005222	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1335916005223	putative tRNA-binding site [nucleotide binding]; other site
1335916005224	B3/4 domain; Region: B3_4; pfam03483
1335916005225	tRNA synthetase B5 domain; Region: B5; smart00874
1335916005226	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1335916005227	dimer interface [polypeptide binding]; other site
1335916005228	motif 1; other site
1335916005229	motif 3; other site
1335916005230	motif 2; other site
1335916005231	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1335916005232	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1335916005233	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1335916005234	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1335916005235	dimer interface [polypeptide binding]; other site
1335916005236	motif 1; other site
1335916005237	active site
1335916005238	motif 2; other site
1335916005239	motif 3; other site
1335916005240	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1335916005241	23S rRNA binding site [nucleotide binding]; other site
1335916005242	L21 binding site [polypeptide binding]; other site
1335916005243	L13 binding site [polypeptide binding]; other site
1335916005244	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1335916005245	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1335916005246	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1335916005247	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1335916005248	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1335916005249	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1335916005250	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1335916005251	active site
1335916005252	dimer interface [polypeptide binding]; other site
1335916005253	motif 1; other site
1335916005254	motif 2; other site
1335916005255	motif 3; other site
1335916005256	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1335916005257	anticodon binding site; other site
1335916005258	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
1335916005259	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916005260	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
1335916005261	6-phosphofructokinase 2; Provisional; Region: PRK10294
1335916005262	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1335916005263	putative substrate binding site [chemical binding]; other site
1335916005264	putative ATP binding site [chemical binding]; other site
1335916005265	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
1335916005266	Phosphotransferase enzyme family; Region: APH; pfam01636
1335916005267	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1335916005268	active site
1335916005269	ATP binding site [chemical binding]; other site
1335916005270	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1335916005271	YniB-like protein; Region: YniB; pfam14002
1335916005272	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1335916005273	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1335916005274	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916005275	motif II; other site
1335916005276	inner membrane protein; Provisional; Region: PRK11648
1335916005277	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1335916005278	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1335916005279	cell division modulator; Provisional; Region: PRK10113
1335916005280	hydroperoxidase II; Provisional; Region: katE; PRK11249
1335916005281	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
1335916005282	tetramer interface [polypeptide binding]; other site
1335916005283	heme binding pocket [chemical binding]; other site
1335916005284	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
1335916005285	domain interactions; other site
1335916005286	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
1335916005287	putative active site [active]
1335916005288	YdjC motif; other site
1335916005289	Mg binding site [ion binding]; other site
1335916005290	putative homodimer interface [polypeptide binding]; other site
1335916005291	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1335916005292	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1335916005293	NAD binding site [chemical binding]; other site
1335916005294	sugar binding site [chemical binding]; other site
1335916005295	divalent metal binding site [ion binding]; other site
1335916005296	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1335916005297	dimer interface [polypeptide binding]; other site
1335916005298	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
1335916005299	Cupin domain; Region: Cupin_2; pfam07883
1335916005300	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916005301	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1335916005302	methionine cluster; other site
1335916005303	active site
1335916005304	phosphorylation site [posttranslational modification]
1335916005305	metal binding site [ion binding]; metal-binding site
1335916005306	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
1335916005307	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1335916005308	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1335916005309	active site
1335916005310	P-loop; other site
1335916005311	phosphorylation site [posttranslational modification]
1335916005312	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
1335916005313	NAD+ synthetase; Region: nadE; TIGR00552
1335916005314	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1335916005315	homodimer interface [polypeptide binding]; other site
1335916005316	NAD binding pocket [chemical binding]; other site
1335916005317	ATP binding pocket [chemical binding]; other site
1335916005318	Mg binding site [ion binding]; other site
1335916005319	active-site loop [active]
1335916005320	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
1335916005321	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1335916005322	GIY-YIG motif/motif A; other site
1335916005323	active site
1335916005324	catalytic site [active]
1335916005325	putative DNA binding site [nucleotide binding]; other site
1335916005326	metal binding site [ion binding]; metal-binding site
1335916005327	hypothetical protein; Provisional; Region: PRK11396
1335916005328	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1335916005329	dimer interface [polypeptide binding]; other site
1335916005330	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
1335916005331	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
1335916005332	putative active site [active]
1335916005333	Zn binding site [ion binding]; other site
1335916005334	succinylarginine dihydrolase; Provisional; Region: PRK13281
1335916005335	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
1335916005336	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
1335916005337	NAD(P) binding site [chemical binding]; other site
1335916005338	catalytic residues [active]
1335916005339	arginine succinyltransferase; Provisional; Region: PRK10456
1335916005340	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
1335916005341	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
1335916005342	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1335916005343	inhibitor-cofactor binding pocket; inhibition site
1335916005344	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916005345	catalytic residue [active]
1335916005346	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1335916005347	putative catalytic site [active]
1335916005348	putative phosphate binding site [ion binding]; other site
1335916005349	active site
1335916005350	metal binding site A [ion binding]; metal-binding site
1335916005351	DNA binding site [nucleotide binding]
1335916005352	putative AP binding site [nucleotide binding]; other site
1335916005353	putative metal binding site B [ion binding]; other site
1335916005354	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1335916005355	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1335916005356	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1335916005357	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1335916005358	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1335916005359	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1335916005360	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
1335916005361	hypothetical protein; Provisional; Region: PRK11622
1335916005362	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
1335916005363	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916005364	dimer interface [polypeptide binding]; other site
1335916005365	conserved gate region; other site
1335916005366	putative PBP binding loops; other site
1335916005367	ABC-ATPase subunit interface; other site
1335916005368	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
1335916005369	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916005370	Walker A/P-loop; other site
1335916005371	ATP binding site [chemical binding]; other site
1335916005372	Q-loop/lid; other site
1335916005373	ABC transporter signature motif; other site
1335916005374	Walker B; other site
1335916005375	D-loop; other site
1335916005376	H-loop/switch region; other site
1335916005377	Rhodanese Homology Domain; Region: RHOD; smart00450
1335916005378	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
1335916005379	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1335916005380	active site residue [active]
1335916005381	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1335916005382	active site residue [active]
1335916005383	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
1335916005384	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1335916005385	active site
1335916005386	8-oxo-dGMP binding site [chemical binding]; other site
1335916005387	nudix motif; other site
1335916005388	metal binding site [ion binding]; metal-binding site
1335916005389	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
1335916005390	glutamate dehydrogenase; Provisional; Region: PRK09414
1335916005391	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1335916005392	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1335916005393	NAD(P) binding site [chemical binding]; other site
1335916005394	hypothetical protein; Provisional; Region: PRK11380
1335916005395	selenophosphate synthetase; Provisional; Region: PRK00943
1335916005396	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1335916005397	dimerization interface [polypeptide binding]; other site
1335916005398	putative ATP binding site [chemical binding]; other site
1335916005399	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1335916005400	putative FMN binding site [chemical binding]; other site
1335916005401	protease 4; Provisional; Region: PRK10949
1335916005402	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1335916005403	tandem repeat interface [polypeptide binding]; other site
1335916005404	oligomer interface [polypeptide binding]; other site
1335916005405	active site residues [active]
1335916005406	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
1335916005407	tandem repeat interface [polypeptide binding]; other site
1335916005408	oligomer interface [polypeptide binding]; other site
1335916005409	active site residues [active]
1335916005410	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1335916005411	active site
1335916005412	homodimer interface [polypeptide binding]; other site
1335916005413	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1335916005414	Isochorismatase family; Region: Isochorismatase; pfam00857
1335916005415	catalytic triad [active]
1335916005416	metal binding site [ion binding]; metal-binding site
1335916005417	conserved cis-peptide bond; other site
1335916005418	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1335916005419	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916005420	putative substrate translocation pore; other site
1335916005421	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916005422	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1335916005423	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1335916005424	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1335916005425	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1335916005426	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1335916005427	active site
1335916005428	catalytic tetrad [active]
1335916005429	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1335916005430	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1335916005431	substrate binding site [chemical binding]; other site
1335916005432	ATP binding site [chemical binding]; other site
1335916005433	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1335916005434	intersubunit interface [polypeptide binding]; other site
1335916005435	active site
1335916005436	zinc binding site [ion binding]; other site
1335916005437	Na+ binding site [ion binding]; other site
1335916005438	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1335916005439	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
1335916005440	inhibitor binding site; inhibition site
1335916005441	catalytic Zn binding site [ion binding]; other site
1335916005442	structural Zn binding site [ion binding]; other site
1335916005443	NADP binding site [chemical binding]; other site
1335916005444	tetramer interface [polypeptide binding]; other site
1335916005445	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916005446	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916005447	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1335916005448	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
1335916005449	putative NAD(P) binding site [chemical binding]; other site
1335916005450	catalytic Zn binding site [ion binding]; other site
1335916005451	structural Zn binding site [ion binding]; other site
1335916005452	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
1335916005453	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1335916005454	SelR domain; Region: SelR; pfam01641
1335916005455	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1335916005456	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1335916005457	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1335916005458	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1335916005459	active site
1335916005460	phosphate binding residues; other site
1335916005461	catalytic residues [active]
1335916005462	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1335916005463	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1335916005464	active site
1335916005465	catalytic tetrad [active]
1335916005466	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1335916005467	PrkA family serine protein kinase; Provisional; Region: PRK15455
1335916005468	AAA ATPase domain; Region: AAA_16; pfam13191
1335916005469	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
1335916005470	hypothetical protein; Provisional; Region: PRK05325
1335916005471	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1335916005472	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1335916005473	metal binding site [ion binding]; metal-binding site
1335916005474	active site
1335916005475	I-site; other site
1335916005476	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1335916005477	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1335916005478	metal binding site [ion binding]; metal-binding site
1335916005479	active site
1335916005480	I-site; other site
1335916005481	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
1335916005482	putative deacylase active site [active]
1335916005483	Predicted membrane protein [Function unknown]; Region: COG2707
1335916005484	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1335916005485	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916005486	cyanate transporter; Region: CynX; TIGR00896
1335916005487	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916005488	putative substrate translocation pore; other site
1335916005489	Uncharacterized conserved protein [Function unknown]; Region: COG3189
1335916005490	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1335916005491	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1335916005492	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1335916005493	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1335916005494	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1335916005495	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1335916005496	metal binding site [ion binding]; metal-binding site
1335916005497	active site
1335916005498	I-site; other site
1335916005499	hypothetical protein; Provisional; Region: PRK10457
1335916005500	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1335916005501	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1335916005502	Probable transposase; Region: OrfB_IS605; pfam01385
1335916005503	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1335916005504	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1335916005505	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
1335916005506	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1335916005507	leucine export protein LeuE; Provisional; Region: PRK10958
1335916005508	transcriptional activator TtdR; Provisional; Region: PRK09801
1335916005509	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916005510	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
1335916005511	putative effector binding pocket; other site
1335916005512	putative dimerization interface [polypeptide binding]; other site
1335916005513	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
1335916005514	tartrate dehydrogenase; Region: TTC; TIGR02089
1335916005515	putative transporter; Provisional; Region: PRK09950
1335916005516	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1335916005517	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
1335916005518	[2Fe-2S] cluster binding site [ion binding]; other site
1335916005519	C-terminal catalytic domain of the oxygenase alpha subunit of an uncharacterized subgroup of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C_2; cd08886
1335916005520	putative alpha subunit interface [polypeptide binding]; other site
1335916005521	putative active site [active]
1335916005522	putative substrate binding site [chemical binding]; other site
1335916005523	Fe binding site [ion binding]; other site
1335916005524	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
1335916005525	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
1335916005526	FMN-binding pocket [chemical binding]; other site
1335916005527	flavin binding motif; other site
1335916005528	phosphate binding motif [ion binding]; other site
1335916005529	beta-alpha-beta structure motif; other site
1335916005530	NAD binding pocket [chemical binding]; other site
1335916005531	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1335916005532	catalytic loop [active]
1335916005533	iron binding site [ion binding]; other site
1335916005534	ribonuclease D; Provisional; Region: PRK10829
1335916005535	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1335916005536	catalytic site [active]
1335916005537	putative active site [active]
1335916005538	putative substrate binding site [chemical binding]; other site
1335916005539	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1335916005540	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1335916005541	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1335916005542	acyl-activating enzyme (AAE) consensus motif; other site
1335916005543	putative AMP binding site [chemical binding]; other site
1335916005544	putative active site [active]
1335916005545	putative CoA binding site [chemical binding]; other site
1335916005546	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
1335916005547	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1335916005548	Glycoprotease family; Region: Peptidase_M22; pfam00814
1335916005549	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1335916005550	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1335916005551	DEAD_2; Region: DEAD_2; pfam06733
1335916005552	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1335916005553	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1335916005554	homotrimer interaction site [polypeptide binding]; other site
1335916005555	putative active site [active]
1335916005556	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
1335916005557	hypothetical protein; Provisional; Region: PRK05114
1335916005558	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
1335916005559	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1335916005560	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
1335916005561	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1335916005562	putative active site [active]
1335916005563	putative CoA binding site [chemical binding]; other site
1335916005564	nudix motif; other site
1335916005565	metal binding site [ion binding]; metal-binding site
1335916005566	L-serine deaminase; Provisional; Region: PRK15023
1335916005567	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1335916005568	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1335916005569	phage resistance protein; Provisional; Region: PRK10551
1335916005570	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1335916005571	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1335916005572	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1335916005573	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1335916005574	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1335916005575	Transporter associated domain; Region: CorC_HlyC; smart01091
1335916005576	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1335916005577	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1335916005578	active pocket/dimerization site; other site
1335916005579	active site
1335916005580	phosphorylation site [posttranslational modification]
1335916005581	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1335916005582	active site
1335916005583	phosphorylation site [posttranslational modification]
1335916005584	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1335916005585	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1335916005586	Predicted membrane protein [Function unknown]; Region: COG4811
1335916005587	hypothetical protein; Provisional; Region: PRK11469
1335916005588	Domain of unknown function DUF; Region: DUF204; pfam02659
1335916005589	Domain of unknown function DUF; Region: DUF204; pfam02659
1335916005590	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1335916005591	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916005592	S-adenosylmethionine binding site [chemical binding]; other site
1335916005593	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1335916005594	DNA-binding site [nucleotide binding]; DNA binding site
1335916005595	RNA-binding motif; other site
1335916005596	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
1335916005597	YebO-like protein; Region: YebO; pfam13974
1335916005598	PhoPQ regulatory protein; Provisional; Region: PRK10299
1335916005599	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
1335916005600	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1335916005601	dimerization interface [polypeptide binding]; other site
1335916005602	putative Zn2+ binding site [ion binding]; other site
1335916005603	putative DNA binding site [nucleotide binding]; other site
1335916005604	Bacterial transcriptional regulator; Region: IclR; pfam01614
1335916005605	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916005606	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1335916005607	putative substrate translocation pore; other site
1335916005608	Predicted integral membrane protein [Function unknown]; Region: COG5521
1335916005609	heat shock protein HtpX; Provisional; Region: PRK05457
1335916005610	carboxy-terminal protease; Provisional; Region: PRK11186
1335916005611	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1335916005612	protein binding site [polypeptide binding]; other site
1335916005613	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1335916005614	Catalytic dyad [active]
1335916005615	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1335916005616	ProP expression regulator; Provisional; Region: PRK04950
1335916005617	ProQ/FINO family; Region: ProQ; pfam04352
1335916005618	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1335916005619	GAF domain; Region: GAF_2; pfam13185
1335916005620	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
1335916005621	Paraquat-inducible protein A; Region: PqiA; pfam04403
1335916005622	Paraquat-inducible protein A; Region: PqiA; pfam04403
1335916005623	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1335916005624	mce related protein; Region: MCE; pfam02470
1335916005625	mce related protein; Region: MCE; pfam02470
1335916005626	mce related protein; Region: MCE; pfam02470
1335916005627	mce related protein; Region: MCE; pfam02470
1335916005628	mce related protein; Region: MCE; pfam02470
1335916005629	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
1335916005630	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916005631	S-adenosylmethionine binding site [chemical binding]; other site
1335916005632	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
1335916005633	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
1335916005634	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1335916005635	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
1335916005636	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1335916005637	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1335916005638	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1335916005639	hypothetical protein; Provisional; Region: PRK10301
1335916005640	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
1335916005641	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1335916005642	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
1335916005643	exodeoxyribonuclease X; Provisional; Region: PRK07983
1335916005644	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1335916005645	active site
1335916005646	catalytic site [active]
1335916005647	substrate binding site [chemical binding]; other site
1335916005648	protease 2; Provisional; Region: PRK10115
1335916005649	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1335916005650	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
1335916005651	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
1335916005652	putative metal binding site [ion binding]; other site
1335916005653	hypothetical protein; Provisional; Region: PRK13680
1335916005654	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
1335916005655	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1335916005656	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1335916005657	ATP-grasp domain; Region: ATP-grasp; pfam02222
1335916005658	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1335916005659	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1335916005660	active site
1335916005661	intersubunit interface [polypeptide binding]; other site
1335916005662	catalytic residue [active]
1335916005663	phosphogluconate dehydratase; Validated; Region: PRK09054
1335916005664	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1335916005665	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1335916005666	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1335916005667	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1335916005668	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
1335916005669	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1335916005670	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1335916005671	putative active site [active]
1335916005672	pyruvate kinase; Provisional; Region: PRK05826
1335916005673	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1335916005674	domain interfaces; other site
1335916005675	active site
1335916005676	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1335916005677	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1335916005678	putative acyl-acceptor binding pocket; other site
1335916005679	putative peptidase; Provisional; Region: PRK11649
1335916005680	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1335916005681	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1335916005682	Peptidase family M23; Region: Peptidase_M23; pfam01551
1335916005683	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
1335916005684	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1335916005685	metal binding site [ion binding]; metal-binding site
1335916005686	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1335916005687	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1335916005688	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1335916005689	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1335916005690	ABC-ATPase subunit  interface; other site
1335916005691	dimer interface [polypeptide binding]; other site
1335916005692	putative PBP binding regions; other site
1335916005693	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1335916005694	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1335916005695	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1335916005696	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1335916005697	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916005698	Walker A motif; other site
1335916005699	ATP binding site [chemical binding]; other site
1335916005700	Walker B motif; other site
1335916005701	arginine finger; other site
1335916005702	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1335916005703	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1335916005704	RuvA N terminal domain; Region: RuvA_N; pfam01330
1335916005705	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1335916005706	hypothetical protein; Provisional; Region: PRK11470
1335916005707	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1335916005708	active site
1335916005709	putative DNA-binding cleft [nucleotide binding]; other site
1335916005710	dimer interface [polypeptide binding]; other site
1335916005711	hypothetical protein; Validated; Region: PRK00110
1335916005712	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1335916005713	nudix motif; other site
1335916005714	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1335916005715	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1335916005716	dimer interface [polypeptide binding]; other site
1335916005717	anticodon binding site; other site
1335916005718	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1335916005719	homodimer interface [polypeptide binding]; other site
1335916005720	motif 1; other site
1335916005721	active site
1335916005722	motif 2; other site
1335916005723	GAD domain; Region: GAD; pfam02938
1335916005724	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1335916005725	motif 3; other site
1335916005726	Isochorismatase family; Region: Isochorismatase; pfam00857
1335916005727	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1335916005728	catalytic triad [active]
1335916005729	conserved cis-peptide bond; other site
1335916005730	hypothetical protein; Provisional; Region: PRK10302
1335916005731	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
1335916005732	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916005733	S-adenosylmethionine binding site [chemical binding]; other site
1335916005734	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916005735	S-adenosylmethionine binding site [chemical binding]; other site
1335916005736	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1335916005737	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1335916005738	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1335916005739	molybdopterin cofactor binding site [chemical binding]; other site
1335916005740	substrate binding site [chemical binding]; other site
1335916005741	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1335916005742	molybdopterin cofactor binding site; other site
1335916005743	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
1335916005744	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
1335916005745	copper homeostasis protein CutC; Provisional; Region: PRK11572
1335916005746	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1335916005747	putative metal binding site [ion binding]; other site
1335916005748	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1335916005749	arginyl-tRNA synthetase; Region: argS; TIGR00456
1335916005750	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1335916005751	active site
1335916005752	HIGH motif; other site
1335916005753	KMSK motif region; other site
1335916005754	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1335916005755	tRNA binding surface [nucleotide binding]; other site
1335916005756	anticodon binding site; other site
1335916005757	Flagellar protein FlhE; Region: FlhE; pfam06366
1335916005758	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1335916005759	FHIPEP family; Region: FHIPEP; pfam00771
1335916005760	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1335916005761	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1335916005762	chemotaxis regulator CheZ; Provisional; Region: PRK11166
1335916005763	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
1335916005764	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916005765	active site
1335916005766	phosphorylation site [posttranslational modification]
1335916005767	intermolecular recognition site; other site
1335916005768	dimerization interface [polypeptide binding]; other site
1335916005769	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1335916005770	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916005771	active site
1335916005772	phosphorylation site [posttranslational modification]
1335916005773	intermolecular recognition site; other site
1335916005774	dimerization interface [polypeptide binding]; other site
1335916005775	CheB methylesterase; Region: CheB_methylest; pfam01339
1335916005776	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
1335916005777	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1335916005778	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916005779	S-adenosylmethionine binding site [chemical binding]; other site
1335916005780	methyl-accepting protein IV; Provisional; Region: PRK09793
1335916005781	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1335916005782	dimer interface [polypeptide binding]; other site
1335916005783	ligand binding site [chemical binding]; other site
1335916005784	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1335916005785	dimerization interface [polypeptide binding]; other site
1335916005786	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1335916005787	dimer interface [polypeptide binding]; other site
1335916005788	putative CheW interface [polypeptide binding]; other site
1335916005789	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1335916005790	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1335916005791	dimer interface [polypeptide binding]; other site
1335916005792	ligand binding site [chemical binding]; other site
1335916005793	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1335916005794	dimerization interface [polypeptide binding]; other site
1335916005795	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1335916005796	dimer interface [polypeptide binding]; other site
1335916005797	putative CheW interface [polypeptide binding]; other site
1335916005798	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1335916005799	putative CheA interaction surface; other site
1335916005800	chemotaxis protein CheA; Provisional; Region: PRK10547
1335916005801	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1335916005802	putative binding surface; other site
1335916005803	active site
1335916005804	CheY binding; Region: CheY-binding; pfam09078
1335916005805	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1335916005806	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916005807	ATP binding site [chemical binding]; other site
1335916005808	Mg2+ binding site [ion binding]; other site
1335916005809	G-X-G motif; other site
1335916005810	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1335916005811	flagellar motor protein MotB; Validated; Region: motB; PRK09041
1335916005812	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1335916005813	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1335916005814	ligand binding site [chemical binding]; other site
1335916005815	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1335916005816	flagellar motor protein MotA; Validated; Region: PRK09110
1335916005817	transcriptional activator FlhC; Provisional; Region: PRK12722
1335916005818	transcriptional activator FlhD; Provisional; Region: PRK02909
1335916005819	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1335916005820	Ligand Binding Site [chemical binding]; other site
1335916005821	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
1335916005822	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
1335916005823	active site
1335916005824	homotetramer interface [polypeptide binding]; other site
1335916005825	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
1335916005826	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
1335916005827	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1335916005828	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1335916005829	TM-ABC transporter signature motif; other site
1335916005830	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
1335916005831	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1335916005832	Walker A/P-loop; other site
1335916005833	ATP binding site [chemical binding]; other site
1335916005834	Q-loop/lid; other site
1335916005835	ABC transporter signature motif; other site
1335916005836	Walker B; other site
1335916005837	D-loop; other site
1335916005838	H-loop/switch region; other site
1335916005839	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1335916005840	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
1335916005841	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
1335916005842	ligand binding site [chemical binding]; other site
1335916005843	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1335916005844	Ferritin-like domain; Region: Ferritin; pfam00210
1335916005845	ferroxidase diiron center [ion binding]; other site
1335916005846	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
1335916005847	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1335916005848	Ferritin-like domain; Region: Ferritin; pfam00210
1335916005849	ferroxidase diiron center [ion binding]; other site
1335916005850	probable metal-binding protein; Region: matur_matur; TIGR03853
1335916005851	tyrosine transporter TyrP; Provisional; Region: PRK15132
1335916005852	aromatic amino acid transport protein; Region: araaP; TIGR00837
1335916005853	hypothetical protein; Provisional; Region: PRK10396
1335916005854	yecA family protein; Region: ygfB_yecA; TIGR02292
1335916005855	SEC-C motif; Region: SEC-C; pfam02810
1335916005856	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
1335916005857	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1335916005858	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1335916005859	GIY-YIG motif/motif A; other site
1335916005860	active site
1335916005861	catalytic site [active]
1335916005862	putative DNA binding site [nucleotide binding]; other site
1335916005863	metal binding site [ion binding]; metal-binding site
1335916005864	UvrB/uvrC motif; Region: UVR; pfam02151
1335916005865	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1335916005866	Helix-hairpin-helix motif; Region: HHH; pfam00633
1335916005867	response regulator; Provisional; Region: PRK09483
1335916005868	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916005869	active site
1335916005870	phosphorylation site [posttranslational modification]
1335916005871	intermolecular recognition site; other site
1335916005872	dimerization interface [polypeptide binding]; other site
1335916005873	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916005874	DNA binding residues [nucleotide binding]
1335916005875	dimerization interface [polypeptide binding]; other site
1335916005876	hypothetical protein; Provisional; Region: PRK10613
1335916005877	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
1335916005878	Autoinducer binding domain; Region: Autoind_bind; pfam03472
1335916005879	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916005880	DNA binding residues [nucleotide binding]
1335916005881	dimerization interface [polypeptide binding]; other site
1335916005882	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
1335916005883	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1335916005884	Walker A/P-loop; other site
1335916005885	ATP binding site [chemical binding]; other site
1335916005886	Q-loop/lid; other site
1335916005887	ABC transporter signature motif; other site
1335916005888	Walker B; other site
1335916005889	D-loop; other site
1335916005890	H-loop/switch region; other site
1335916005891	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1335916005892	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916005893	dimer interface [polypeptide binding]; other site
1335916005894	conserved gate region; other site
1335916005895	putative PBP binding loops; other site
1335916005896	ABC-ATPase subunit interface; other site
1335916005897	D-cysteine desulfhydrase; Validated; Region: PRK03910
1335916005898	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
1335916005899	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916005900	catalytic residue [active]
1335916005901	cystine transporter subunit; Provisional; Region: PRK11260
1335916005902	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916005903	substrate binding pocket [chemical binding]; other site
1335916005904	membrane-bound complex binding site; other site
1335916005905	hinge residues; other site
1335916005906	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
1335916005907	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1335916005908	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1335916005909	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1335916005910	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1335916005911	DNA binding residues [nucleotide binding]
1335916005912	flagellin; Validated; Region: PRK08026
1335916005913	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1335916005914	Flagellin protein; Region: FliC; pfam12445
1335916005915	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1335916005916	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1335916005917	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1335916005918	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1335916005919	Flagellar protein FliS; Region: FliS; cl00654
1335916005920	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
1335916005921	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1335916005922	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1335916005923	active site
1335916005924	Na/Ca binding site [ion binding]; other site
1335916005925	catalytic site [active]
1335916005926	lipoprotein; Provisional; Region: PRK10397
1335916005927	putative inner membrane protein; Provisional; Region: PRK11099
1335916005928	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
1335916005929	CPxP  motif; other site
1335916005930	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1335916005931	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1335916005932	Probable transposase; Region: OrfB_IS605; pfam01385
1335916005933	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1335916005934	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1335916005935	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1335916005936	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1335916005937	substrate binding site [chemical binding]; other site
1335916005938	multidrug efflux protein; Reviewed; Region: emrE; PRK09541
1335916005939	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
1335916005940	flagellar motor switch protein FliG; Region: fliG; TIGR00207
1335916005941	FliG C-terminal domain; Region: FliG_C; pfam01706
1335916005942	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1335916005943	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
1335916005944	Flagellar assembly protein FliH; Region: FliH; pfam02108
1335916005945	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
1335916005946	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1335916005947	Walker A motif/ATP binding site; other site
1335916005948	Walker B motif; other site
1335916005949	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
1335916005950	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1335916005951	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
1335916005952	flagellar hook-length control protein; Provisional; Region: PRK10118
1335916005953	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
1335916005954	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1335916005955	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1335916005956	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
1335916005957	flagellar motor switch protein; Validated; Region: fliN; PRK05698
1335916005958	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
1335916005959	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1335916005960	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1335916005961	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1335916005962	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
1335916005963	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916005964	DNA binding residues [nucleotide binding]
1335916005965	dimerization interface [polypeptide binding]; other site
1335916005966	hypothetical protein; Provisional; Region: PRK10708
1335916005967	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
1335916005968	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
1335916005969	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916005970	active site
1335916005971	motif I; other site
1335916005972	motif II; other site
1335916005973	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
1335916005974	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1335916005975	metal binding site [ion binding]; metal-binding site
1335916005976	active site
1335916005977	I-site; other site
1335916005978	Uncharacterized small protein [Function unknown]; Region: COG5475
1335916005979	hypothetical protein; Provisional; Region: PRK10062
1335916005980	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1335916005981	EamA-like transporter family; Region: EamA; pfam00892
1335916005982	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
1335916005983	additional DNA contacts [nucleotide binding]; other site
1335916005984	mismatch recognition site; other site
1335916005985	active site
1335916005986	zinc binding site [ion binding]; other site
1335916005987	DNA intercalation site [nucleotide binding]; other site
1335916005988	DNA cytosine methylase; Provisional; Region: PRK10458
1335916005989	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1335916005990	cofactor binding site; other site
1335916005991	DNA binding site [nucleotide binding]
1335916005992	substrate interaction site [chemical binding]; other site
1335916005993	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1335916005994	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1335916005995	Zn2+ binding site [ion binding]; other site
1335916005996	Mg2+ binding site [ion binding]; other site
1335916005997	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1335916005998	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1335916005999	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1335916006000	eyelet of channel; other site
1335916006001	trimer interface [polypeptide binding]; other site
1335916006002	chaperone protein HchA; Provisional; Region: PRK04155
1335916006003	Type 1 glutamine amidotransferase (GATase1)-like domain found in Escherichia coli Hsp31 protein (EcHsp31); Region: GATase1_EcHsp31_like; cd03148
1335916006004	dimer interface [polypeptide binding]; other site
1335916006005	metal binding site [ion binding]; metal-binding site
1335916006006	potential oxyanion hole; other site
1335916006007	potential catalytic triad [active]
1335916006008	conserved cys residue [active]
1335916006009	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1335916006010	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916006011	dimer interface [polypeptide binding]; other site
1335916006012	phosphorylation site [posttranslational modification]
1335916006013	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916006014	ATP binding site [chemical binding]; other site
1335916006015	Mg2+ binding site [ion binding]; other site
1335916006016	G-X-G motif; other site
1335916006017	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
1335916006018	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916006019	active site
1335916006020	phosphorylation site [posttranslational modification]
1335916006021	intermolecular recognition site; other site
1335916006022	dimerization interface [polypeptide binding]; other site
1335916006023	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1335916006024	DNA binding site [nucleotide binding]
1335916006025	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1335916006026	active site
1335916006027	homotetramer interface [polypeptide binding]; other site
1335916006028	TMAO/DMSO reductase; Reviewed; Region: PRK05363
1335916006029	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
1335916006030	Moco binding site; other site
1335916006031	metal coordination site [ion binding]; other site
1335916006032	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
1335916006033	zinc/cadmium-binding protein; Provisional; Region: PRK10306
1335916006034	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1335916006035	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
1335916006036	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1335916006037	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1335916006038	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1335916006039	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1335916006040	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1335916006041	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
1335916006042	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1335916006043	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
1335916006044	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1335916006045	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
1335916006046	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1335916006047	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1335916006048	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1335916006049	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1335916006050	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1335916006051	shikimate transporter; Provisional; Region: PRK09952
1335916006052	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916006053	putative substrate translocation pore; other site
1335916006054	AMP nucleosidase; Provisional; Region: PRK08292
1335916006055	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
1335916006056	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
1335916006057	hypothetical protein; Provisional; Region: PRK12378
1335916006058	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916006059	Transcriptional regulator; Region: Transcrip_reg; cl00361
1335916006060	MATE family multidrug exporter; Provisional; Region: PRK10189
1335916006061	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
1335916006062	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
1335916006063	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916006064	The C-terminal substrate binding domain of LysR-type transcriptional regulator Cbl, which is required for expression of sulfate starvation-inducible (ssi) genes, contains the type 2 periplasmic binding fold; Region: PBP2_Cbl; cd08444
1335916006065	putative substrate binding site [chemical binding]; other site
1335916006066	dimerization interface [polypeptide binding]; other site
1335916006067	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
1335916006068	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916006069	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1335916006070	putative dimerization interface [polypeptide binding]; other site
1335916006071	L,D-transpeptidase; Provisional; Region: PRK10190
1335916006072	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1335916006073	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
1335916006074	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1335916006075	putative dimer interface [polypeptide binding]; other site
1335916006076	active site pocket [active]
1335916006077	putative cataytic base [active]
1335916006078	cobalamin 5'-phosphate synthase/cobalamin synthase; Region: cobS; TIGR00317
1335916006079	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1335916006080	homotrimer interface [polypeptide binding]; other site
1335916006081	Walker A motif; other site
1335916006082	GTP binding site [chemical binding]; other site
1335916006083	Walker B motif; other site
1335916006084	hypothetical protein; Provisional; Region: PRK05423
1335916006085	Predicted membrane protein [Function unknown]; Region: COG1289
1335916006086	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1335916006087	DNA gyrase inhibitor; Provisional; Region: PRK10016
1335916006088	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
1335916006089	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1335916006090	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1335916006091	exonuclease I; Provisional; Region: sbcB; PRK11779
1335916006092	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1335916006093	active site
1335916006094	catalytic site [active]
1335916006095	substrate binding site [chemical binding]; other site
1335916006096	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1335916006097	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
1335916006098	CPxP  motif; other site
1335916006099	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
1335916006100	Sulphur transport; Region: Sulf_transp; pfam04143
1335916006101	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1335916006102	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916006103	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1335916006104	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1335916006105	dimerization interface [polypeptide binding]; other site
1335916006106	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1335916006107	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1335916006108	putative NAD(P) binding site [chemical binding]; other site
1335916006109	Plasmid encoded toxin Txe; Region: Plasmid_Txe; pfam06769
1335916006110	antitoxin YefM; Provisional; Region: PRK11409
1335916006111	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1335916006112	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1335916006113	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1335916006114	Histidinol dehydrogenase; Region: Histidinol_dh; pfam00815
1335916006115	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1335916006116	NAD binding site [chemical binding]; other site
1335916006117	dimerization interface [polypeptide binding]; other site
1335916006118	product binding site; other site
1335916006119	substrate binding site [chemical binding]; other site
1335916006120	zinc binding site [ion binding]; other site
1335916006121	catalytic residues [active]
1335916006122	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
1335916006123	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1335916006124	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916006125	homodimer interface [polypeptide binding]; other site
1335916006126	catalytic residue [active]
1335916006127	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1335916006128	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916006129	active site
1335916006130	motif I; other site
1335916006131	motif II; other site
1335916006132	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1335916006133	putative active site pocket [active]
1335916006134	4-fold oligomerization interface [polypeptide binding]; other site
1335916006135	metal binding residues [ion binding]; metal-binding site
1335916006136	3-fold/trimer interface [polypeptide binding]; other site
1335916006137	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1335916006138	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1335916006139	putative active site [active]
1335916006140	oxyanion strand; other site
1335916006141	catalytic triad [active]
1335916006142	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1335916006143	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1335916006144	catalytic residues [active]
1335916006145	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1335916006146	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1335916006147	substrate binding site [chemical binding]; other site
1335916006148	glutamase interaction surface [polypeptide binding]; other site
1335916006149	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1335916006150	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1335916006151	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1335916006152	metal binding site [ion binding]; metal-binding site
1335916006153	chain length determinant protein WzzB; Provisional; Region: PRK15471
1335916006154	Chain length determinant protein; Region: Wzz; pfam02706
1335916006155	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
1335916006156	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1335916006157	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1335916006158	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1335916006159	phosphomannomutase CpsG; Provisional; Region: PRK15414
1335916006160	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1335916006161	active site
1335916006162	substrate binding site [chemical binding]; other site
1335916006163	metal binding site [ion binding]; metal-binding site
1335916006164	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1335916006165	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1335916006166	Substrate binding site; other site
1335916006167	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1335916006168	sugar transferase, PEP-CTERM/EpsH1 system associated; Region: stp1; TIGR03087
1335916006169	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
1335916006170	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
1335916006171	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1335916006172	NAD binding site [chemical binding]; other site
1335916006173	homodimer interface [polypeptide binding]; other site
1335916006174	active site
1335916006175	substrate binding site [chemical binding]; other site
1335916006176	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
1335916006177	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1335916006178	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1335916006179	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1335916006180	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1335916006181	active site
1335916006182	O-antigen polysaccharide polymerase Wzy; Region: O-ag_pol_Wzy; pfam14296
1335916006183	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1335916006184	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1335916006185	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1335916006186	active site
1335916006187	tetramer interface; other site
1335916006188	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
1335916006189	colanic acid biosynthesis glycosyltransferase WcaL; Region: wcaL; TIGR04005
1335916006190	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
1335916006191	putative ADP-binding pocket [chemical binding]; other site
1335916006192	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
1335916006193	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
1335916006194	colanic acid exporter; Provisional; Region: PRK10459
1335916006195	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
1335916006196	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
1335916006197	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
1335916006198	phosphomannomutase CpsG; Provisional; Region: PRK15414
1335916006199	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1335916006200	active site
1335916006201	substrate binding site [chemical binding]; other site
1335916006202	metal binding site [ion binding]; metal-binding site
1335916006203	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
1335916006204	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1335916006205	Substrate binding site; other site
1335916006206	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1335916006207	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
1335916006208	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
1335916006209	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
1335916006210	active site
1335916006211	GDP-Mannose binding site [chemical binding]; other site
1335916006212	dimer interface [polypeptide binding]; other site
1335916006213	modified nudix motif
1335916006214	metal binding site [ion binding]; metal-binding site
1335916006215	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1335916006216	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1335916006217	NADP binding site [chemical binding]; other site
1335916006218	active site
1335916006219	putative substrate binding site [chemical binding]; other site
1335916006220	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1335916006221	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1335916006222	NADP-binding site; other site
1335916006223	homotetramer interface [polypeptide binding]; other site
1335916006224	substrate binding site [chemical binding]; other site
1335916006225	homodimer interface [polypeptide binding]; other site
1335916006226	active site
1335916006227	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
1335916006228	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
1335916006229	putative trimer interface [polypeptide binding]; other site
1335916006230	putative active site [active]
1335916006231	putative substrate binding site [chemical binding]; other site
1335916006232	putative CoA binding site [chemical binding]; other site
1335916006233	putative glycosyl transferase; Provisional; Region: PRK10063
1335916006234	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1335916006235	metal-binding site
1335916006236	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
1335916006237	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1335916006238	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
1335916006239	putative acyl transferase; Provisional; Region: PRK10191
1335916006240	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1335916006241	trimer interface [polypeptide binding]; other site
1335916006242	active site
1335916006243	substrate binding site [chemical binding]; other site
1335916006244	CoA binding site [chemical binding]; other site
1335916006245	putative glycosyl transferase; Provisional; Region: PRK10018
1335916006246	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1335916006247	active site
1335916006248	tyrosine kinase; Provisional; Region: PRK11519
1335916006249	Chain length determinant protein; Region: Wzz; pfam02706
1335916006250	Chain length determinant protein; Region: Wzz; cl15801
1335916006251	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1335916006252	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1335916006253	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1335916006254	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1335916006255	active site
1335916006256	polysaccharide export protein Wza; Provisional; Region: PRK15078
1335916006257	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1335916006258	SLBB domain; Region: SLBB; pfam10531
1335916006259	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1335916006260	FOG: CBS domain [General function prediction only]; Region: COG0517
1335916006261	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1335916006262	Transporter associated domain; Region: CorC_HlyC; smart01091
1335916006263	Phage-related protein [Function unknown]; Region: COG4679
1335916006264	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
1335916006265	putative assembly protein; Provisional; Region: PRK10833
1335916006266	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1335916006267	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1335916006268	trimer interface [polypeptide binding]; other site
1335916006269	active site
1335916006270	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1335916006271	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1335916006272	ATP-binding site [chemical binding]; other site
1335916006273	Sugar specificity; other site
1335916006274	Pyrimidine base specificity; other site
1335916006275	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
1335916006276	putative diguanylate cyclase; Provisional; Region: PRK09776
1335916006277	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1335916006278	putative active site [active]
1335916006279	heme pocket [chemical binding]; other site
1335916006280	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1335916006281	putative active site [active]
1335916006282	heme pocket [chemical binding]; other site
1335916006283	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1335916006284	putative active site [active]
1335916006285	heme pocket [chemical binding]; other site
1335916006286	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1335916006287	metal binding site [ion binding]; metal-binding site
1335916006288	active site
1335916006289	I-site; other site
1335916006290	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1335916006291	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
1335916006292	AlkA N-terminal domain; Region: AlkA_N; smart01009
1335916006293	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1335916006294	minor groove reading motif; other site
1335916006295	helix-hairpin-helix signature motif; other site
1335916006296	substrate binding pocket [chemical binding]; other site
1335916006297	active site
1335916006298	putative chaperone; Provisional; Region: PRK11678
1335916006299	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1335916006300	nucleotide binding site [chemical binding]; other site
1335916006301	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1335916006302	SBD interface [polypeptide binding]; other site
1335916006303	Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only]; Region: COG4248
1335916006304	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1335916006305	substrate binding site [chemical binding]; other site
1335916006306	activation loop (A-loop); other site
1335916006307	Y-family of DNA polymerases; Region: PolY; cl12025
1335916006308	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3779
1335916006309	Uncharacterized protein conserved in bacteria (DUF2314); Region: DUF2314; pfam10077
1335916006310	Protein phosphatase 2C; Region: PP2C_2; pfam13672
1335916006311	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
1335916006312	metal ion-dependent adhesion site (MIDAS); other site
1335916006313	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
1335916006314	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1335916006315	HlyD family secretion protein; Region: HlyD_3; pfam13437
1335916006316	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1335916006317	Protein export membrane protein; Region: SecD_SecF; cl14618
1335916006318	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1335916006319	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
1335916006320	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1335916006321	dimerization interface [polypeptide binding]; other site
1335916006322	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916006323	dimer interface [polypeptide binding]; other site
1335916006324	phosphorylation site [posttranslational modification]
1335916006325	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916006326	ATP binding site [chemical binding]; other site
1335916006327	Mg2+ binding site [ion binding]; other site
1335916006328	G-X-G motif; other site
1335916006329	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
1335916006330	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916006331	active site
1335916006332	phosphorylation site [posttranslational modification]
1335916006333	intermolecular recognition site; other site
1335916006334	dimerization interface [polypeptide binding]; other site
1335916006335	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1335916006336	DNA binding site [nucleotide binding]
1335916006337	Uncharacterized conserved protein [Function unknown]; Region: COG3422
1335916006338	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
1335916006339	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
1335916006340	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
1335916006341	putative protease; Provisional; Region: PRK15452
1335916006342	Peptidase family U32; Region: Peptidase_U32; pfam01136
1335916006343	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
1335916006344	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1335916006345	tail protein; Provisional; Region: D; PHA02561
1335916006346	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
1335916006347	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1335916006348	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1335916006349	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1335916006350	major tail tube protein; Provisional; Region: FII; PHA02600
1335916006351	major tail sheath protein; Provisional; Region: FI; PHA02560
1335916006352	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1335916006353	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1335916006354	catalytic residues [active]
1335916006355	catalytic nucleophile [active]
1335916006356	Presynaptic Site I dimer interface [polypeptide binding]; other site
1335916006357	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1335916006358	Synaptic Flat tetramer interface [polypeptide binding]; other site
1335916006359	Synaptic Site I dimer interface [polypeptide binding]; other site
1335916006360	DNA binding site [nucleotide binding]
1335916006361	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1335916006362	DNA-binding interface [nucleotide binding]; DNA binding site
1335916006363	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1335916006364	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1335916006365	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1335916006366	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
1335916006367	baseplate assembly protein; Provisional; Region: J; PHA02568
1335916006368	baseplate wedge subunit; Provisional; Region: W; PHA02516
1335916006369	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1335916006370	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1335916006371	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
1335916006372	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1335916006373	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
1335916006374	The lysozyme from bacteriophage lambda hydrolyses the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc), as do other lysozymes.  But unlike other lysozymes, bacteriophage lambda does not produce a reducing...; Region: bacteriophage_lambda_lysozyme; cd00736
1335916006375	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1335916006376	catalytic residue [active]
1335916006377	Phage holin family 2; Region: Phage_holin_2; pfam04550
1335916006378	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1335916006379	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1335916006380	terminase endonuclease subunit; Provisional; Region: M; PHA02537
1335916006381	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1335916006382	Phage major capsid protein, P2 family; Region: Phage_cap_P2; pfam05125
1335916006383	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
1335916006384	terminase ATPase subunit; Provisional; Region: P; PHA02535
1335916006385	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1335916006386	portal vertex protein; Provisional; Region: Q; PHA02536
1335916006387	Phage portal protein; Region: Phage_portal; pfam04860
1335916006388	AAA domain; Region: AAA_21; pfam13304
1335916006389	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916006390	Walker B; other site
1335916006391	D-loop; other site
1335916006392	H-loop/switch region; other site
1335916006393	DksA-like zinc finger domain containing protein; Region: PHA00080
1335916006394	Regulatory phage protein cox; Region: Phage_Cox; pfam10743
1335916006395	integrase; Provisional; Region: int; PHA02601
1335916006396	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
1335916006397	dimer interface [polypeptide binding]; other site
1335916006398	active site
1335916006399	catalytic residues [active]
1335916006400	Int/Topo IB signature motif; other site
1335916006401	lipid kinase; Reviewed; Region: PRK13054
1335916006402	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1335916006403	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1335916006404	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1335916006405	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1335916006406	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
1335916006407	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
1335916006408	putative NAD(P) binding site [chemical binding]; other site
1335916006409	catalytic Zn binding site [ion binding]; other site
1335916006410	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1335916006411	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
1335916006412	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1335916006413	active site
1335916006414	P-loop; other site
1335916006415	phosphorylation site [posttranslational modification]
1335916006416	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1335916006417	active site
1335916006418	phosphorylation site [posttranslational modification]
1335916006419	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
1335916006420	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1335916006421	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1335916006422	intersubunit interface [polypeptide binding]; other site
1335916006423	active site
1335916006424	zinc binding site [ion binding]; other site
1335916006425	Na+ binding site [ion binding]; other site
1335916006426	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
1335916006427	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1335916006428	putative active site; other site
1335916006429	catalytic residue [active]
1335916006430	nucleoside transporter; Region: 2A0110; TIGR00889
1335916006431	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916006432	putative substrate translocation pore; other site
1335916006433	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1335916006434	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1335916006435	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1335916006436	substrate binding site [chemical binding]; other site
1335916006437	ATP binding site [chemical binding]; other site
1335916006438	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1335916006439	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916006440	DNA-binding site [nucleotide binding]; DNA binding site
1335916006441	UTRA domain; Region: UTRA; pfam07702
1335916006442	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
1335916006443	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
1335916006444	active site
1335916006445	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1335916006446	dimer interface [polypeptide binding]; other site
1335916006447	substrate binding site [chemical binding]; other site
1335916006448	ATP binding site [chemical binding]; other site
1335916006449	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1335916006450	substrate binding site [chemical binding]; other site
1335916006451	multimerization interface [polypeptide binding]; other site
1335916006452	ATP binding site [chemical binding]; other site
1335916006453	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1335916006454	putative metal binding site [ion binding]; other site
1335916006455	putative homodimer interface [polypeptide binding]; other site
1335916006456	putative homotetramer interface [polypeptide binding]; other site
1335916006457	putative homodimer-homodimer interface [polypeptide binding]; other site
1335916006458	putative allosteric switch controlling residues; other site
1335916006459	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
1335916006460	Predicted integral membrane protein [Function unknown]; Region: COG5455
1335916006461	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
1335916006462	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
1335916006463	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
1335916006464	PapC N-terminal domain; Region: PapC_N; pfam13954
1335916006465	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1335916006466	PapC C-terminal domain; Region: PapC_C; pfam13953
1335916006467	putative fimbrial assembly chaperone protein StcB; Provisional; Region: PRK15253
1335916006468	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1335916006469	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1335916006470	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1335916006471	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
1335916006472	antiporter inner membrane protein; Provisional; Region: PRK11670
1335916006473	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1335916006474	Walker A motif; other site
1335916006475	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1335916006476	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1335916006477	active site
1335916006478	HIGH motif; other site
1335916006479	KMSKS motif; other site
1335916006480	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1335916006481	tRNA binding surface [nucleotide binding]; other site
1335916006482	anticodon binding site; other site
1335916006483	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1335916006484	dimer interface [polypeptide binding]; other site
1335916006485	putative tRNA-binding site [nucleotide binding]; other site
1335916006486	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
1335916006487	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
1335916006488	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
1335916006489	MoxR-like ATPases [General function prediction only]; Region: COG0714
1335916006490	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916006491	Walker A motif; other site
1335916006492	ATP binding site [chemical binding]; other site
1335916006493	Walker B motif; other site
1335916006494	arginine finger; other site
1335916006495	VWA domain containing CoxE-like protein; Region: VWA_CoxE; pfam05762
1335916006496	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1335916006497	metal ion-dependent adhesion site (MIDAS); other site
1335916006498	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1335916006499	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
1335916006500	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1335916006501	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1335916006502	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1335916006503	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916006504	active site
1335916006505	phosphorylation site [posttranslational modification]
1335916006506	intermolecular recognition site; other site
1335916006507	dimerization interface [polypeptide binding]; other site
1335916006508	LytTr DNA-binding domain; Region: LytTR; pfam04397
1335916006509	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1335916006510	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1335916006511	GAF domain; Region: GAF; pfam01590
1335916006512	Histidine kinase; Region: His_kinase; pfam06580
1335916006513	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916006514	ATP binding site [chemical binding]; other site
1335916006515	Mg2+ binding site [ion binding]; other site
1335916006516	G-X-G motif; other site
1335916006517	transcriptional regulator MirA; Provisional; Region: PRK15043
1335916006518	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
1335916006519	DNA binding residues [nucleotide binding]
1335916006520	hypothetical protein; Provisional; Region: PRK13681
1335916006521	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1335916006522	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916006523	dimer interface [polypeptide binding]; other site
1335916006524	conserved gate region; other site
1335916006525	putative PBP binding loops; other site
1335916006526	ABC-ATPase subunit interface; other site
1335916006527	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1335916006528	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1335916006529	Walker A/P-loop; other site
1335916006530	ATP binding site [chemical binding]; other site
1335916006531	Q-loop/lid; other site
1335916006532	ABC transporter signature motif; other site
1335916006533	Walker B; other site
1335916006534	D-loop; other site
1335916006535	H-loop/switch region; other site
1335916006536	CBS domain; Region: CBS; pfam00571
1335916006537	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916006538	dimer interface [polypeptide binding]; other site
1335916006539	conserved gate region; other site
1335916006540	ABC-ATPase subunit interface; other site
1335916006541	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1335916006542	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1335916006543	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1335916006544	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1335916006545	D-lactate dehydrogenase; Provisional; Region: PRK11183
1335916006546	FAD binding domain; Region: FAD_binding_4; pfam01565
1335916006547	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
1335916006548	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
1335916006549	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1335916006550	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
1335916006551	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1335916006552	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1335916006553	oxidoreductase; Provisional; Region: PRK12743
1335916006554	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1335916006555	NAD(P) binding site [chemical binding]; other site
1335916006556	active site
1335916006557	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
1335916006558	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1335916006559	FMN binding site [chemical binding]; other site
1335916006560	active site
1335916006561	catalytic residues [active]
1335916006562	substrate binding site [chemical binding]; other site
1335916006563	hypothetical protein; Provisional; Region: PRK01821
1335916006564	hypothetical protein; Provisional; Region: PRK10711
1335916006565	cytidine deaminase; Provisional; Region: PRK09027
1335916006566	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1335916006567	active site
1335916006568	catalytic motif [active]
1335916006569	Zn binding site [ion binding]; other site
1335916006570	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1335916006571	active site
1335916006572	catalytic motif [active]
1335916006573	Zn binding site [ion binding]; other site
1335916006574	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1335916006575	putative active site [active]
1335916006576	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
1335916006577	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
1335916006578	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1335916006579	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916006580	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1335916006581	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1335916006582	TM-ABC transporter signature motif; other site
1335916006583	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1335916006584	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
1335916006585	Walker A/P-loop; other site
1335916006586	ATP binding site [chemical binding]; other site
1335916006587	Q-loop/lid; other site
1335916006588	ABC transporter signature motif; other site
1335916006589	Walker B; other site
1335916006590	D-loop; other site
1335916006591	H-loop/switch region; other site
1335916006592	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1335916006593	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1335916006594	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1335916006595	ligand binding site [chemical binding]; other site
1335916006596	calcium binding site [ion binding]; other site
1335916006597	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
1335916006598	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1335916006599	DNA binding site [nucleotide binding]
1335916006600	domain linker motif; other site
1335916006601	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1335916006602	dimerization interface (closed form) [polypeptide binding]; other site
1335916006603	ligand binding site [chemical binding]; other site
1335916006604	Predicted membrane protein [Function unknown]; Region: COG2311
1335916006605	hypothetical protein; Provisional; Region: PRK10835
1335916006606	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
1335916006607	homodecamer interface [polypeptide binding]; other site
1335916006608	GTP cyclohydrolase I; Provisional; Region: PLN03044
1335916006609	active site
1335916006610	putative catalytic site residues [active]
1335916006611	zinc binding site [ion binding]; other site
1335916006612	GTP-CH-I/GFRP interaction surface; other site
1335916006613	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1335916006614	S-formylglutathione hydrolase; Region: PLN02442
1335916006615	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
1335916006616	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1335916006617	N-terminal plug; other site
1335916006618	ligand-binding site [chemical binding]; other site
1335916006619	lysine transporter; Provisional; Region: PRK10836
1335916006620	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1335916006621	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916006622	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1335916006623	putative dimerization interface [polypeptide binding]; other site
1335916006624	conserved hypothetical integral membrane protein; Region: TIGR00698
1335916006625	endonuclease IV; Provisional; Region: PRK01060
1335916006626	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1335916006627	AP (apurinic/apyrimidinic) site pocket; other site
1335916006628	DNA interaction; other site
1335916006629	Metal-binding active site; metal-binding site
1335916006630	putative kinase; Provisional; Region: PRK09954
1335916006631	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
1335916006632	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
1335916006633	substrate binding site [chemical binding]; other site
1335916006634	ATP binding site [chemical binding]; other site
1335916006635	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1335916006636	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1335916006637	Nucleoside recognition; Region: Gate; pfam07670
1335916006638	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1335916006639	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1335916006640	active site
1335916006641	tetramer interface [polypeptide binding]; other site
1335916006642	DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402
1335916006643	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1335916006644	ligand binding site [chemical binding]; other site
1335916006645	flexible hinge region; other site
1335916006646	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1335916006647	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1335916006648	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1335916006649	Nucleoside recognition; Region: Gate; pfam07670
1335916006650	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1335916006651	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
1335916006652	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
1335916006653	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1335916006654	substrate binding site [chemical binding]; other site
1335916006655	ATP binding site [chemical binding]; other site
1335916006656	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
1335916006657	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
1335916006658	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1335916006659	active site
1335916006660	P-loop; other site
1335916006661	phosphorylation site [posttranslational modification]
1335916006662	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1335916006663	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1335916006664	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1335916006665	putative substrate binding site [chemical binding]; other site
1335916006666	putative ATP binding site [chemical binding]; other site
1335916006667	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
1335916006668	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1335916006669	active site
1335916006670	phosphorylation site [posttranslational modification]
1335916006671	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1335916006672	dimerization domain swap beta strand [polypeptide binding]; other site
1335916006673	regulatory protein interface [polypeptide binding]; other site
1335916006674	active site
1335916006675	regulatory phosphorylation site [posttranslational modification]; other site
1335916006676	sugar efflux transporter B; Provisional; Region: PRK15011
1335916006677	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916006678	putative substrate translocation pore; other site
1335916006679	Flagellin N-methylase; Region: FliB; pfam03692
1335916006680	elongation factor P; Provisional; Region: PRK04542
1335916006681	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1335916006682	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1335916006683	RNA binding site [nucleotide binding]; other site
1335916006684	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1335916006685	RNA binding site [nucleotide binding]; other site
1335916006686	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1335916006687	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1335916006688	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1335916006689	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1335916006690	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1335916006691	active site
1335916006692	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
1335916006693	NlpC/P60 family; Region: NLPC_P60; pfam00877
1335916006694	phage resistance protein; Provisional; Region: PRK10551
1335916006695	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1335916006696	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1335916006697	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1335916006698	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1335916006699	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1335916006700	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916006701	dimer interface [polypeptide binding]; other site
1335916006702	conserved gate region; other site
1335916006703	putative PBP binding loops; other site
1335916006704	ABC-ATPase subunit interface; other site
1335916006705	microcin C ABC transporter permease; Provisional; Region: PRK15021
1335916006706	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916006707	dimer interface [polypeptide binding]; other site
1335916006708	conserved gate region; other site
1335916006709	ABC-ATPase subunit interface; other site
1335916006710	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
1335916006711	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1335916006712	Walker A/P-loop; other site
1335916006713	ATP binding site [chemical binding]; other site
1335916006714	Q-loop/lid; other site
1335916006715	ABC transporter signature motif; other site
1335916006716	Walker B; other site
1335916006717	D-loop; other site
1335916006718	H-loop/switch region; other site
1335916006719	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1335916006720	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1335916006721	Walker A/P-loop; other site
1335916006722	ATP binding site [chemical binding]; other site
1335916006723	Q-loop/lid; other site
1335916006724	ABC transporter signature motif; other site
1335916006725	Walker B; other site
1335916006726	D-loop; other site
1335916006727	H-loop/switch region; other site
1335916006728	hypothetical protein; Provisional; Region: PRK11835
1335916006729	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916006730	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1335916006731	putative substrate translocation pore; other site
1335916006732	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1335916006733	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1335916006734	RNA binding surface [nucleotide binding]; other site
1335916006735	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1335916006736	active site
1335916006737	uracil binding [chemical binding]; other site
1335916006738	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1335916006739	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1335916006740	ATP binding site [chemical binding]; other site
1335916006741	putative Mg++ binding site [ion binding]; other site
1335916006742	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1335916006743	nucleotide binding region [chemical binding]; other site
1335916006744	ATP-binding site [chemical binding]; other site
1335916006745	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
1335916006746	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1335916006747	5S rRNA interface [nucleotide binding]; other site
1335916006748	CTC domain interface [polypeptide binding]; other site
1335916006749	L16 interface [polypeptide binding]; other site
1335916006750	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1335916006751	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1335916006752	hypothetical protein; Provisional; Region: PRK13689
1335916006753	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
1335916006754	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1335916006755	Sulfatase; Region: Sulfatase; pfam00884
1335916006756	transcriptional regulator NarP; Provisional; Region: PRK10403
1335916006757	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916006758	active site
1335916006759	phosphorylation site [posttranslational modification]
1335916006760	intermolecular recognition site; other site
1335916006761	dimerization interface [polypeptide binding]; other site
1335916006762	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916006763	DNA binding residues [nucleotide binding]
1335916006764	dimerization interface [polypeptide binding]; other site
1335916006765	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
1335916006766	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
1335916006767	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1335916006768	binding surface
1335916006769	TPR motif; other site
1335916006770	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1335916006771	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1335916006772	catalytic residues [active]
1335916006773	central insert; other site
1335916006774	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1335916006775	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
1335916006776	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1335916006777	heme exporter protein CcmC; Region: ccmC; TIGR01191
1335916006778	heme exporter protein CcmB; Region: ccmB; TIGR01190
1335916006779	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
1335916006780	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
1335916006781	Walker A/P-loop; other site
1335916006782	ATP binding site [chemical binding]; other site
1335916006783	Q-loop/lid; other site
1335916006784	ABC transporter signature motif; other site
1335916006785	Walker B; other site
1335916006786	D-loop; other site
1335916006787	H-loop/switch region; other site
1335916006788	cytochrome c-type protein NapC; Provisional; Region: PRK10617
1335916006789	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
1335916006790	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
1335916006791	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
1335916006792	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1335916006793	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1335916006794	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
1335916006795	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
1335916006796	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1335916006797	[4Fe-4S] binding site [ion binding]; other site
1335916006798	molybdopterin cofactor binding site; other site
1335916006799	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1335916006800	molybdopterin cofactor binding site; other site
1335916006801	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
1335916006802	ferredoxin-type protein; Provisional; Region: PRK10194
1335916006803	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
1335916006804	secondary substrate binding site; other site
1335916006805	primary substrate binding site; other site
1335916006806	inhibition loop; other site
1335916006807	dimerization interface [polypeptide binding]; other site
1335916006808	malate:quinone oxidoreductase; Validated; Region: PRK05257
1335916006809	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
1335916006810	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
1335916006811	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1335916006812	Walker A/P-loop; other site
1335916006813	ATP binding site [chemical binding]; other site
1335916006814	Q-loop/lid; other site
1335916006815	ABC transporter signature motif; other site
1335916006816	Walker B; other site
1335916006817	D-loop; other site
1335916006818	H-loop/switch region; other site
1335916006819	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
1335916006820	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
1335916006821	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1335916006822	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916006823	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916006824	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1335916006825	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1335916006826	DNA binding site [nucleotide binding]
1335916006827	active site
1335916006828	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
1335916006829	ApbE family; Region: ApbE; pfam02424
1335916006830	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
1335916006831	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916006832	ATP binding site [chemical binding]; other site
1335916006833	G-X-G motif; other site
1335916006834	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1335916006835	putative binding surface; other site
1335916006836	active site
1335916006837	transcriptional regulator RcsB; Provisional; Region: PRK10840
1335916006838	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916006839	active site
1335916006840	phosphorylation site [posttranslational modification]
1335916006841	intermolecular recognition site; other site
1335916006842	dimerization interface [polypeptide binding]; other site
1335916006843	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916006844	DNA binding residues [nucleotide binding]
1335916006845	dimerization interface [polypeptide binding]; other site
1335916006846	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
1335916006847	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916006848	dimer interface [polypeptide binding]; other site
1335916006849	phosphorylation site [posttranslational modification]
1335916006850	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916006851	ATP binding site [chemical binding]; other site
1335916006852	Mg2+ binding site [ion binding]; other site
1335916006853	G-X-G motif; other site
1335916006854	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
1335916006855	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916006856	active site
1335916006857	phosphorylation site [posttranslational modification]
1335916006858	intermolecular recognition site; other site
1335916006859	dimerization interface [polypeptide binding]; other site
1335916006860	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4676
1335916006861	Uncharacterized protein conserved in bacteria (DUF2135); Region: DUF2135; pfam09906
1335916006862	Predicted secreted protein [Function unknown]; Region: COG5445
1335916006863	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
1335916006864	Predicted secreted protein [Function unknown]; Region: COG5445
1335916006865	Stage II sporulation protein; Region: SpoIID; pfam08486
1335916006866	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
1335916006867	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1335916006868	MG2 domain; Region: A2M_N; pfam01835
1335916006869	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
1335916006870	Alpha-2-macroglobulin family; Region: A2M; pfam00207
1335916006871	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
1335916006872	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3234
1335916006873	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4685
1335916006874	DNA gyrase subunit A; Validated; Region: PRK05560
1335916006875	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1335916006876	CAP-like domain; other site
1335916006877	active site
1335916006878	primary dimer interface [polypeptide binding]; other site
1335916006879	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1335916006880	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1335916006881	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1335916006882	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1335916006883	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1335916006884	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1335916006885	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1335916006886	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916006887	S-adenosylmethionine binding site [chemical binding]; other site
1335916006888	adhesin; Provisional; Region: PRK09752
1335916006889	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1335916006890	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1335916006891	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1335916006892	ATP cone domain; Region: ATP-cone; pfam03477
1335916006893	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1335916006894	active site
1335916006895	dimer interface [polypeptide binding]; other site
1335916006896	catalytic residues [active]
1335916006897	effector binding site; other site
1335916006898	R2 peptide binding site; other site
1335916006899	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1335916006900	dimer interface [polypeptide binding]; other site
1335916006901	putative radical transfer pathway; other site
1335916006902	diiron center [ion binding]; other site
1335916006903	tyrosyl radical; other site
1335916006904	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1335916006905	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1335916006906	catalytic loop [active]
1335916006907	iron binding site [ion binding]; other site
1335916006908	hypothetical protein; Provisional; Region: PRK09902
1335916006909	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
1335916006910	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
1335916006911	active site
1335916006912	catalytic site [active]
1335916006913	metal binding site [ion binding]; metal-binding site
1335916006914	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
1335916006915	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916006916	putative substrate translocation pore; other site
1335916006917	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
1335916006918	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1335916006919	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1335916006920	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
1335916006921	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
1335916006922	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
1335916006923	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1335916006924	Cysteine-rich domain; Region: CCG; pfam02754
1335916006925	Cysteine-rich domain; Region: CCG; pfam02754
1335916006926	hypothetical protein; Provisional; Region: PRK09956
1335916006927	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1335916006928	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1335916006929	hypothetical protein; Provisional; Region: PRK03673
1335916006930	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1335916006931	putative MPT binding site; other site
1335916006932	Competence-damaged protein; Region: CinA; cl00666
1335916006933	YfaZ precursor; Region: YfaZ; pfam07437
1335916006934	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
1335916006935	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
1335916006936	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1335916006937	catalytic core [active]
1335916006938	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1335916006939	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1335916006940	inhibitor-cofactor binding pocket; inhibition site
1335916006941	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916006942	catalytic residue [active]
1335916006943	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1335916006944	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1335916006945	Ligand binding site; other site
1335916006946	Putative Catalytic site; other site
1335916006947	DXD motif; other site
1335916006948	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
1335916006949	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
1335916006950	putative active site [active]
1335916006951	putative catalytic site [active]
1335916006952	putative Zn binding site [ion binding]; other site
1335916006953	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1335916006954	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1335916006955	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
1335916006956	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1335916006957	signal transduction protein PmrD; Provisional; Region: PRK15450
1335916006958	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
1335916006959	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1335916006960	acyl-activating enzyme (AAE) consensus motif; other site
1335916006961	putative AMP binding site [chemical binding]; other site
1335916006962	putative active site [active]
1335916006963	putative CoA binding site [chemical binding]; other site
1335916006964	O-succinylbenzoate synthase; Provisional; Region: PRK05105
1335916006965	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1335916006966	active site
1335916006967	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1335916006968	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1335916006969	substrate binding site [chemical binding]; other site
1335916006970	oxyanion hole (OAH) forming residues; other site
1335916006971	trimer interface [polypeptide binding]; other site
1335916006972	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
1335916006973	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
1335916006974	nucleophilic elbow; other site
1335916006975	catalytic triad; other site
1335916006976	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1335916006977	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1335916006978	dimer interface [polypeptide binding]; other site
1335916006979	tetramer interface [polypeptide binding]; other site
1335916006980	PYR/PP interface [polypeptide binding]; other site
1335916006981	TPP binding site [chemical binding]; other site
1335916006982	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1335916006983	TPP-binding site; other site
1335916006984	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
1335916006985	isochorismate synthases; Region: isochor_syn; TIGR00543
1335916006986	hypothetical protein; Provisional; Region: PRK10404
1335916006987	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1335916006988	Coenzyme A binding pocket [chemical binding]; other site
1335916006989	ribonuclease BN; Region: true_RNase_BN; TIGR02649
1335916006990	deubiquitinase; Provisional; Region: PRK11836
1335916006991	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
1335916006992	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1335916006993	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1335916006994	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1335916006995	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1335916006996	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1335916006997	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1335916006998	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1335916006999	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1335916007000	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1335916007001	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1335916007002	4Fe-4S binding domain; Region: Fer4; pfam00037
1335916007003	4Fe-4S binding domain; Region: Fer4; pfam00037
1335916007004	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1335916007005	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1335916007006	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1335916007007	catalytic loop [active]
1335916007008	iron binding site [ion binding]; other site
1335916007009	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1335916007010	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1335916007011	[4Fe-4S] binding site [ion binding]; other site
1335916007012	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1335916007013	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1335916007014	SLBB domain; Region: SLBB; pfam10531
1335916007015	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1335916007016	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1335916007017	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1335916007018	putative dimer interface [polypeptide binding]; other site
1335916007019	[2Fe-2S] cluster binding site [ion binding]; other site
1335916007020	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1335916007021	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1335916007022	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1335916007023	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1335916007024	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1335916007025	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1335916007026	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916007027	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
1335916007028	putative dimerization interface [polypeptide binding]; other site
1335916007029	aminotransferase AlaT; Validated; Region: PRK09265
1335916007030	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1335916007031	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916007032	homodimer interface [polypeptide binding]; other site
1335916007033	catalytic residue [active]
1335916007034	5'-nucleotidase; Provisional; Region: PRK03826
1335916007035	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1335916007036	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1335916007037	TrkA-C domain; Region: TrkA_C; pfam02080
1335916007038	TrkA-C domain; Region: TrkA_C; pfam02080
1335916007039	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1335916007040	putative phosphatase; Provisional; Region: PRK11587
1335916007041	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916007042	motif II; other site
1335916007043	hypothetical protein; Validated; Region: PRK05445
1335916007044	hypothetical protein; Provisional; Region: PRK01816
1335916007045	phosphate acetyltransferase; Reviewed; Region: PRK05632
1335916007046	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1335916007047	DRTGG domain; Region: DRTGG; pfam07085
1335916007048	phosphate acetyltransferase; Region: pta; TIGR00651
1335916007049	hypothetical protein; Provisional; Region: PRK11588
1335916007050	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1335916007051	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
1335916007052	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
1335916007053	nudix motif; other site
1335916007054	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1335916007055	active site
1335916007056	metal binding site [ion binding]; metal-binding site
1335916007057	homotetramer interface [polypeptide binding]; other site
1335916007058	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
1335916007059	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1335916007060	C-terminal domain interface [polypeptide binding]; other site
1335916007061	GSH binding site (G-site) [chemical binding]; other site
1335916007062	dimer interface [polypeptide binding]; other site
1335916007063	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
1335916007064	N-terminal domain interface [polypeptide binding]; other site
1335916007065	putative dimer interface [polypeptide binding]; other site
1335916007066	active site
1335916007067	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1335916007068	homooctamer interface [polypeptide binding]; other site
1335916007069	active site
1335916007070	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1335916007071	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1335916007072	putative NAD(P) binding site [chemical binding]; other site
1335916007073	putative active site [active]
1335916007074	putative transposase; Provisional; Region: PRK09857
1335916007075	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1335916007076	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
1335916007077	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1335916007078	Walker A/P-loop; other site
1335916007079	ATP binding site [chemical binding]; other site
1335916007080	Q-loop/lid; other site
1335916007081	ABC transporter signature motif; other site
1335916007082	Walker B; other site
1335916007083	D-loop; other site
1335916007084	H-loop/switch region; other site
1335916007085	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916007086	dimer interface [polypeptide binding]; other site
1335916007087	conserved gate region; other site
1335916007088	putative PBP binding loops; other site
1335916007089	ABC-ATPase subunit interface; other site
1335916007090	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1335916007091	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916007092	dimer interface [polypeptide binding]; other site
1335916007093	conserved gate region; other site
1335916007094	putative PBP binding loops; other site
1335916007095	ABC-ATPase subunit interface; other site
1335916007096	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
1335916007097	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916007098	substrate binding pocket [chemical binding]; other site
1335916007099	membrane-bound complex binding site; other site
1335916007100	hinge residues; other site
1335916007101	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
1335916007102	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916007103	substrate binding pocket [chemical binding]; other site
1335916007104	membrane-bound complex binding site; other site
1335916007105	hinge residues; other site
1335916007106	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1335916007107	Flavoprotein; Region: Flavoprotein; pfam02441
1335916007108	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1335916007109	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1335916007110	active site
1335916007111	tetramer interface [polypeptide binding]; other site
1335916007112	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1335916007113	active site
1335916007114	colicin V production protein; Provisional; Region: PRK10845
1335916007115	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1335916007116	cell division protein DedD; Provisional; Region: PRK11633
1335916007117	Sporulation related domain; Region: SPOR; pfam05036
1335916007118	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1335916007119	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1335916007120	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1335916007121	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1335916007122	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1335916007123	hypothetical protein; Provisional; Region: PRK10847
1335916007124	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1335916007125	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1335916007126	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1335916007127	dimerization interface 3.5A [polypeptide binding]; other site
1335916007128	active site
1335916007129	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
1335916007130	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1335916007131	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
1335916007132	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
1335916007133	ligand binding site [chemical binding]; other site
1335916007134	NAD binding site [chemical binding]; other site
1335916007135	catalytic site [active]
1335916007136	homodimer interface [polypeptide binding]; other site
1335916007137	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
1335916007138	putative transporter; Provisional; Region: PRK12382
1335916007139	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916007140	putative substrate translocation pore; other site
1335916007141	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1335916007142	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1335916007143	dimer interface [polypeptide binding]; other site
1335916007144	active site
1335916007145	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1335916007146	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1335916007147	YfcL protein; Region: YfcL; pfam08891
1335916007148	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
1335916007149	hypothetical protein; Provisional; Region: PRK10621
1335916007150	Predicted permeases [General function prediction only]; Region: COG0730
1335916007151	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
1335916007152	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
1335916007153	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1335916007154	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1335916007155	Tetramer interface [polypeptide binding]; other site
1335916007156	active site
1335916007157	FMN-binding site [chemical binding]; other site
1335916007158	HemK family putative methylases; Region: hemK_fam; TIGR00536
1335916007159	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916007160	S-adenosylmethionine binding site [chemical binding]; other site
1335916007161	hypothetical protein; Provisional; Region: PRK04946
1335916007162	Smr domain; Region: Smr; pfam01713
1335916007163	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
1335916007164	Fimbrial protein; Region: Fimbrial; cl01416
1335916007165	Fimbrial protein; Region: Fimbrial; cl01416
1335916007166	Fimbrial protein; Region: Fimbrial; cl01416
1335916007167	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1335916007168	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1335916007169	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1335916007170	PapC N-terminal domain; Region: PapC_N; pfam13954
1335916007171	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1335916007172	PapC C-terminal domain; Region: PapC_C; pfam13953
1335916007173	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1335916007174	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1335916007175	catalytic core [active]
1335916007176	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
1335916007177	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1335916007178	dimer interface [polypeptide binding]; other site
1335916007179	active site
1335916007180	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
1335916007181	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
1335916007182	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
1335916007183	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
1335916007184	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
1335916007185	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916007186	putative substrate translocation pore; other site
1335916007187	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1335916007188	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1335916007189	putative substrate binding site [chemical binding]; other site
1335916007190	putative ATP binding site [chemical binding]; other site
1335916007191	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
1335916007192	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1335916007193	substrate binding [chemical binding]; other site
1335916007194	active site
1335916007195	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1335916007196	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1335916007197	DNA binding site [nucleotide binding]
1335916007198	domain linker motif; other site
1335916007199	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
1335916007200	Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288
1335916007201	putative dimerization interface [polypeptide binding]; other site
1335916007202	putative ligand binding site [chemical binding]; other site
1335916007203	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1335916007204	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
1335916007205	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1335916007206	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1335916007207	catalytic residue [active]
1335916007208	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916007209	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1335916007210	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916007211	putative substrate translocation pore; other site
1335916007212	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916007213	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
1335916007214	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1335916007215	HlyD family secretion protein; Region: HlyD_3; pfam13437
1335916007216	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
1335916007217	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916007218	active site
1335916007219	phosphorylation site [posttranslational modification]
1335916007220	intermolecular recognition site; other site
1335916007221	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916007222	DNA binding residues [nucleotide binding]
1335916007223	dimerization interface [polypeptide binding]; other site
1335916007224	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
1335916007225	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916007226	substrate binding pocket [chemical binding]; other site
1335916007227	membrane-bound complex binding site; other site
1335916007228	hinge residues; other site
1335916007229	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916007230	substrate binding pocket [chemical binding]; other site
1335916007231	membrane-bound complex binding site; other site
1335916007232	hinge residues; other site
1335916007233	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916007234	dimer interface [polypeptide binding]; other site
1335916007235	phosphorylation site [posttranslational modification]
1335916007236	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916007237	ATP binding site [chemical binding]; other site
1335916007238	Mg2+ binding site [ion binding]; other site
1335916007239	G-X-G motif; other site
1335916007240	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916007241	active site
1335916007242	phosphorylation site [posttranslational modification]
1335916007243	intermolecular recognition site; other site
1335916007244	dimerization interface [polypeptide binding]; other site
1335916007245	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1335916007246	putative binding surface; other site
1335916007247	active site
1335916007248	putative CoA-transferase; Provisional; Region: PRK11430
1335916007249	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1335916007250	putative transporter YfdV; Provisional; Region: PRK09903
1335916007251	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1335916007252	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
1335916007253	TPP-binding site; other site
1335916007254	dimer interface [polypeptide binding]; other site
1335916007255	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916007256	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1335916007257	PYR/PP interface [polypeptide binding]; other site
1335916007258	dimer interface [polypeptide binding]; other site
1335916007259	TPP binding site [chemical binding]; other site
1335916007260	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1335916007261	formyl-coenzyme A transferase; Provisional; Region: PRK05398
1335916007262	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1335916007263	hypothetical protein; Provisional; Region: PRK10316
1335916007264	YfdX protein; Region: YfdX; pfam10938
1335916007265	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
1335916007266	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1335916007267	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1335916007268	putative acyl-acceptor binding pocket; other site
1335916007269	aminotransferase; Validated; Region: PRK08175
1335916007270	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1335916007271	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916007272	homodimer interface [polypeptide binding]; other site
1335916007273	catalytic residue [active]
1335916007274	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1335916007275	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1335916007276	GAF domain; Region: GAF; pfam01590
1335916007277	Histidine kinase; Region: His_kinase; pfam06580
1335916007278	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916007279	ATP binding site [chemical binding]; other site
1335916007280	Mg2+ binding site [ion binding]; other site
1335916007281	G-X-G motif; other site
1335916007282	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1335916007283	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916007284	active site
1335916007285	phosphorylation site [posttranslational modification]
1335916007286	intermolecular recognition site; other site
1335916007287	dimerization interface [polypeptide binding]; other site
1335916007288	LytTr DNA-binding domain; Region: LytTR; pfam04397
1335916007289	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1335916007290	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916007291	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1335916007292	dimerization domain swap beta strand [polypeptide binding]; other site
1335916007293	regulatory protein interface [polypeptide binding]; other site
1335916007294	active site
1335916007295	regulatory phosphorylation site [posttranslational modification]; other site
1335916007296	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1335916007297	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1335916007298	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1335916007299	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1335916007300	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1335916007301	active site
1335916007302	phosphorylation site [posttranslational modification]
1335916007303	exoaminopeptidase; Provisional; Region: PRK09961
1335916007304	M42 Peptidases, also known as glutamyl aminopeptidase family; Region: M42; cd05638
1335916007305	oligomer interface [polypeptide binding]; other site
1335916007306	active site
1335916007307	metal binding site [ion binding]; metal-binding site
1335916007308	aminopeptidase; Provisional; Region: PRK09795
1335916007309	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1335916007310	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1335916007311	active site
1335916007312	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1335916007313	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1335916007314	active site
1335916007315	P-loop; other site
1335916007316	phosphorylation site [posttranslational modification]
1335916007317	glucokinase, proteobacterial type; Region: glk; TIGR00749
1335916007318	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1335916007319	nucleotide binding site [chemical binding]; other site
1335916007320	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1335916007321	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1335916007322	Cl- selectivity filter; other site
1335916007323	Cl- binding residues [ion binding]; other site
1335916007324	pore gating glutamate residue; other site
1335916007325	dimer interface [polypeptide binding]; other site
1335916007326	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1335916007327	manganese transport protein MntH; Reviewed; Region: PRK00701
1335916007328	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1335916007329	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1335916007330	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1335916007331	Nucleoside recognition; Region: Gate; pfam07670
1335916007332	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1335916007333	MASE1; Region: MASE1; pfam05231
1335916007334	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1335916007335	diguanylate cyclase; Region: GGDEF; smart00267
1335916007336	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1335916007337	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1335916007338	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1335916007339	salt bridge; other site
1335916007340	non-specific DNA binding site [nucleotide binding]; other site
1335916007341	sequence-specific DNA binding site [nucleotide binding]; other site
1335916007342	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1335916007343	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1335916007344	active site
1335916007345	HIGH motif; other site
1335916007346	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1335916007347	active site
1335916007348	KMSKS motif; other site
1335916007349	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1335916007350	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916007351	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1335916007352	putative dimerization interface [polypeptide binding]; other site
1335916007353	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1335916007354	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
1335916007355	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
1335916007356	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1335916007357	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1335916007358	nucleotide binding pocket [chemical binding]; other site
1335916007359	K-X-D-G motif; other site
1335916007360	catalytic site [active]
1335916007361	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1335916007362	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1335916007363	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1335916007364	Dimer interface [polypeptide binding]; other site
1335916007365	BRCT sequence motif; other site
1335916007366	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
1335916007367	cell division protein ZipA; Provisional; Region: PRK03427
1335916007368	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
1335916007369	FtsZ protein binding site [polypeptide binding]; other site
1335916007370	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1335916007371	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1335916007372	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1335916007373	dimer interface [polypeptide binding]; other site
1335916007374	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916007375	catalytic residue [active]
1335916007376	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1335916007377	dimerization domain swap beta strand [polypeptide binding]; other site
1335916007378	regulatory protein interface [polypeptide binding]; other site
1335916007379	active site
1335916007380	regulatory phosphorylation site [posttranslational modification]; other site
1335916007381	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1335916007382	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1335916007383	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1335916007384	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1335916007385	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1335916007386	HPr interaction site; other site
1335916007387	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1335916007388	active site
1335916007389	phosphorylation site [posttranslational modification]
1335916007390	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1335916007391	dimer interface [polypeptide binding]; other site
1335916007392	pyridoxamine kinase; Validated; Region: PRK05756
1335916007393	pyridoxal binding site [chemical binding]; other site
1335916007394	ATP binding site [chemical binding]; other site
1335916007395	hypothetical protein; Provisional; Region: PRK10318
1335916007396	cysteine synthase B; Region: cysM; TIGR01138
1335916007397	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1335916007398	dimer interface [polypeptide binding]; other site
1335916007399	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916007400	catalytic residue [active]
1335916007401	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
1335916007402	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1335916007403	Walker A/P-loop; other site
1335916007404	ATP binding site [chemical binding]; other site
1335916007405	Q-loop/lid; other site
1335916007406	ABC transporter signature motif; other site
1335916007407	Walker B; other site
1335916007408	D-loop; other site
1335916007409	H-loop/switch region; other site
1335916007410	TOBE-like domain; Region: TOBE_3; pfam12857
1335916007411	sulfate transport protein; Provisional; Region: cysT; CHL00187
1335916007412	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916007413	dimer interface [polypeptide binding]; other site
1335916007414	conserved gate region; other site
1335916007415	putative PBP binding loops; other site
1335916007416	ABC-ATPase subunit interface; other site
1335916007417	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1335916007418	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916007419	dimer interface [polypeptide binding]; other site
1335916007420	conserved gate region; other site
1335916007421	putative PBP binding loops; other site
1335916007422	ABC-ATPase subunit interface; other site
1335916007423	thiosulfate transporter subunit; Provisional; Region: PRK10852
1335916007424	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1335916007425	short chain dehydrogenase; Provisional; Region: PRK08226
1335916007426	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
1335916007427	NAD binding site [chemical binding]; other site
1335916007428	homotetramer interface [polypeptide binding]; other site
1335916007429	homodimer interface [polypeptide binding]; other site
1335916007430	active site
1335916007431	transcriptional regulator MurR; Provisional; Region: PRK15482
1335916007432	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1335916007433	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1335916007434	putative active site [active]
1335916007435	N-acetylmuramic acid 6-phosphate etherase; Region: TIGR00274
1335916007436	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1335916007437	putative active site [active]
1335916007438	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
1335916007439	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1335916007440	active site turn [active]
1335916007441	phosphorylation site [posttranslational modification]
1335916007442	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1335916007443	putative periplasmic esterase; Provisional; Region: PRK03642
1335916007444	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1335916007445	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
1335916007446	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
1335916007447	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
1335916007448	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
1335916007449	putative acetyltransferase; Provisional; Region: PRK03624
1335916007450	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1335916007451	Coenzyme A binding pocket [chemical binding]; other site
1335916007452	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
1335916007453	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1335916007454	active site
1335916007455	metal binding site [ion binding]; metal-binding site
1335916007456	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1335916007457	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1335916007458	transcriptional regulator EutR; Provisional; Region: PRK10130
1335916007459	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916007460	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916007461	carboxysome structural protein EutK; Provisional; Region: PRK15466
1335916007462	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1335916007463	Hexamer interface [polypeptide binding]; other site
1335916007464	Hexagonal pore residue; other site
1335916007465	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
1335916007466	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
1335916007467	putative hexamer interface [polypeptide binding]; other site
1335916007468	putative hexagonal pore; other site
1335916007469	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
1335916007470	putative hexamer interface [polypeptide binding]; other site
1335916007471	putative hexagonal pore; other site
1335916007472	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
1335916007473	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
1335916007474	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
1335916007475	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
1335916007476	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
1335916007477	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
1335916007478	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
1335916007479	active site
1335916007480	metal binding site [ion binding]; metal-binding site
1335916007481	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
1335916007482	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1335916007483	nucleotide binding site [chemical binding]; other site
1335916007484	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1335916007485	putative catalytic cysteine [active]
1335916007486	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1335916007487	Hexamer/Pentamer interface [polypeptide binding]; other site
1335916007488	central pore; other site
1335916007489	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1335916007490	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1335916007491	Hexamer interface [polypeptide binding]; other site
1335916007492	Hexagonal pore residue; other site
1335916007493	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1335916007494	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
1335916007495	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
1335916007496	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
1335916007497	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1335916007498	G1 box; other site
1335916007499	GTP/Mg2+ binding site [chemical binding]; other site
1335916007500	G2 box; other site
1335916007501	Switch I region; other site
1335916007502	G3 box; other site
1335916007503	Switch II region; other site
1335916007504	G4 box; other site
1335916007505	G5 box; other site
1335916007506	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1335916007507	putative hexamer interface [polypeptide binding]; other site
1335916007508	putative hexagonal pore; other site
1335916007509	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1335916007510	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1335916007511	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1335916007512	putative NAD(P) binding site [chemical binding]; other site
1335916007513	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1335916007514	transaldolase-like protein; Provisional; Region: PTZ00411
1335916007515	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1335916007516	active site
1335916007517	dimer interface [polypeptide binding]; other site
1335916007518	catalytic residue [active]
1335916007519	transketolase; Reviewed; Region: PRK12753
1335916007520	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1335916007521	TPP-binding site [chemical binding]; other site
1335916007522	dimer interface [polypeptide binding]; other site
1335916007523	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1335916007524	PYR/PP interface [polypeptide binding]; other site
1335916007525	dimer interface [polypeptide binding]; other site
1335916007526	TPP binding site [chemical binding]; other site
1335916007527	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1335916007528	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1335916007529	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1335916007530	dimer interface [polypeptide binding]; other site
1335916007531	ADP-ribose binding site [chemical binding]; other site
1335916007532	active site
1335916007533	nudix motif; other site
1335916007534	metal binding site [ion binding]; metal-binding site
1335916007535	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
1335916007536	4Fe-4S binding domain; Region: Fer4; pfam00037
1335916007537	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1335916007538	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916007539	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
1335916007540	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1335916007541	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1335916007542	dimerization interface [polypeptide binding]; other site
1335916007543	Histidine kinase; Region: HisKA_3; pfam07730
1335916007544	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916007545	ATP binding site [chemical binding]; other site
1335916007546	Mg2+ binding site [ion binding]; other site
1335916007547	G-X-G motif; other site
1335916007548	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
1335916007549	Protein export membrane protein; Region: SecD_SecF; cl14618
1335916007550	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1335916007551	ArsC family; Region: ArsC; pfam03960
1335916007552	putative catalytic residues [active]
1335916007553	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1335916007554	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1335916007555	metal binding site [ion binding]; metal-binding site
1335916007556	dimer interface [polypeptide binding]; other site
1335916007557	hypothetical protein; Provisional; Region: PRK13664
1335916007558	putative hydrolase; Provisional; Region: PRK11460
1335916007559	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
1335916007560	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1335916007561	Helicase; Region: Helicase_RecD; pfam05127
1335916007562	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1335916007563	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
1335916007564	Predicted metalloprotease [General function prediction only]; Region: COG2321
1335916007565	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1335916007566	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1335916007567	oligomeric interface; other site
1335916007568	putative active site [active]
1335916007569	homodimer interface [polypeptide binding]; other site
1335916007570	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
1335916007571	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1335916007572	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1335916007573	ATP binding site [chemical binding]; other site
1335916007574	active site
1335916007575	substrate binding site [chemical binding]; other site
1335916007576	lipoprotein; Provisional; Region: PRK11679
1335916007577	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
1335916007578	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1335916007579	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1335916007580	dimer interface [polypeptide binding]; other site
1335916007581	active site
1335916007582	catalytic residue [active]
1335916007583	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
1335916007584	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
1335916007585	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1335916007586	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1335916007587	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1335916007588	catalytic triad [active]
1335916007589	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1335916007590	4Fe-4S binding domain; Region: Fer4; pfam00037
1335916007591	hydrogenase 4 subunit B; Validated; Region: PRK06521
1335916007592	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1335916007593	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1335916007594	NADH dehydrogenase; Region: NADHdh; cl00469
1335916007595	hydrogenase 4 subunit D; Validated; Region: PRK06525
1335916007596	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1335916007597	hydrogenase 4 membrane subunit; Provisional; Region: hyfE; PRK11492
1335916007598	hydrogenase 4 subunit F; Validated; Region: PRK06458
1335916007599	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1335916007600	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
1335916007601	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1335916007602	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
1335916007603	hydrogenase 4 subunit H; Validated; Region: PRK08222
1335916007604	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1335916007605	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
1335916007606	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains [Transcription / Signal transduction mechanisms]; Region: FhlA; COG3604
1335916007607	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1335916007608	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916007609	Walker A motif; other site
1335916007610	ATP binding site [chemical binding]; other site
1335916007611	Walker B motif; other site
1335916007612	arginine finger; other site
1335916007613	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1335916007614	putative formate transporter; Provisional; Region: focB; PRK09713
1335916007615	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1335916007616	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1335916007617	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
1335916007618	Peptidase family M48; Region: Peptidase_M48; cl12018
1335916007619	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1335916007620	ArsC family; Region: ArsC; pfam03960
1335916007621	catalytic residues [active]
1335916007622	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1335916007623	DNA replication initiation factor; Provisional; Region: PRK08084
1335916007624	uracil transporter; Provisional; Region: PRK10720
1335916007625	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1335916007626	active site
1335916007627	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1335916007628	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1335916007629	dimerization interface [polypeptide binding]; other site
1335916007630	putative ATP binding site [chemical binding]; other site
1335916007631	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1335916007632	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1335916007633	active site
1335916007634	substrate binding site [chemical binding]; other site
1335916007635	cosubstrate binding site; other site
1335916007636	catalytic site [active]
1335916007637	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
1335916007638	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1335916007639	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1335916007640	Catalytic C-terminal domain, first repeat, of prokaryotic polyphosphate kinase 1 and similar proteins; Region: PLDc_PPK1_C1; cd09114
1335916007641	domain interface [polypeptide binding]; other site
1335916007642	active site
1335916007643	catalytic site [active]
1335916007644	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1335916007645	putative active site [active]
1335916007646	catalytic site [active]
1335916007647	exopolyphosphatase; Provisional; Region: PRK10854
1335916007648	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1335916007649	MASE1; Region: MASE1; pfam05231
1335916007650	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1335916007651	diguanylate cyclase; Region: GGDEF; smart00267
1335916007652	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1335916007653	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
1335916007654	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
1335916007655	GMP synthase; Reviewed; Region: guaA; PRK00074
1335916007656	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1335916007657	AMP/PPi binding site [chemical binding]; other site
1335916007658	candidate oxyanion hole; other site
1335916007659	catalytic triad [active]
1335916007660	potential glutamine specificity residues [chemical binding]; other site
1335916007661	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1335916007662	ATP Binding subdomain [chemical binding]; other site
1335916007663	Ligand Binding sites [chemical binding]; other site
1335916007664	Dimerization subdomain; other site
1335916007665	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1335916007666	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1335916007667	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1335916007668	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1335916007669	active site
1335916007670	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
1335916007671	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1335916007672	generic binding surface II; other site
1335916007673	generic binding surface I; other site
1335916007674	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
1335916007675	GTP-binding protein Der; Reviewed; Region: PRK00093
1335916007676	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1335916007677	G1 box; other site
1335916007678	GTP/Mg2+ binding site [chemical binding]; other site
1335916007679	Switch I region; other site
1335916007680	G2 box; other site
1335916007681	Switch II region; other site
1335916007682	G3 box; other site
1335916007683	G4 box; other site
1335916007684	G5 box; other site
1335916007685	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1335916007686	G1 box; other site
1335916007687	GTP/Mg2+ binding site [chemical binding]; other site
1335916007688	Switch I region; other site
1335916007689	G2 box; other site
1335916007690	G3 box; other site
1335916007691	Switch II region; other site
1335916007692	G4 box; other site
1335916007693	G5 box; other site
1335916007694	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
1335916007695	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cd00216
1335916007696	Trp docking motif [polypeptide binding]; other site
1335916007697	active site
1335916007698	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1335916007699	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1335916007700	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1335916007701	dimer interface [polypeptide binding]; other site
1335916007702	motif 1; other site
1335916007703	active site
1335916007704	motif 2; other site
1335916007705	motif 3; other site
1335916007706	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1335916007707	anticodon binding site; other site
1335916007708	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1335916007709	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1335916007710	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1335916007711	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1335916007712	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1335916007713	non-specific DNA binding site [nucleotide binding]; other site
1335916007714	salt bridge; other site
1335916007715	sequence-specific DNA binding site [nucleotide binding]; other site
1335916007716	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1335916007717	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1335916007718	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916007719	FeS/SAM binding site; other site
1335916007720	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1335916007721	active site
1335916007722	multimer interface [polypeptide binding]; other site
1335916007723	penicillin-binding protein 1C; Provisional; Region: PRK11240
1335916007724	Transglycosylase; Region: Transgly; pfam00912
1335916007725	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1335916007726	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1335916007727	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1335916007728	MG2 domain; Region: A2M_N; pfam01835
1335916007729	Alpha-2-macroglobulin family; Region: A2M; pfam00207
1335916007730	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1335916007731	surface patch; other site
1335916007732	thioester region; other site
1335916007733	specificity defining residues; other site
1335916007734	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
1335916007735	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1335916007736	active site residue [active]
1335916007737	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1335916007738	active site residue [active]
1335916007739	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
1335916007740	aminopeptidase B; Provisional; Region: PRK05015
1335916007741	Peptidase; Region: DUF3663; pfam12404
1335916007742	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1335916007743	interface (dimer of trimers) [polypeptide binding]; other site
1335916007744	Substrate-binding/catalytic site; other site
1335916007745	Zn-binding sites [ion binding]; other site
1335916007746	hypothetical protein; Provisional; Region: PRK10721
1335916007747	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1335916007748	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1335916007749	catalytic loop [active]
1335916007750	iron binding site [ion binding]; other site
1335916007751	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1335916007752	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
1335916007753	nucleotide binding site [chemical binding]; other site
1335916007754	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1335916007755	SBD interface [polypeptide binding]; other site
1335916007756	co-chaperone HscB; Provisional; Region: hscB; PRK05014
1335916007757	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1335916007758	HSP70 interaction site [polypeptide binding]; other site
1335916007759	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
1335916007760	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
1335916007761	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1335916007762	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1335916007763	trimerization site [polypeptide binding]; other site
1335916007764	active site
1335916007765	cysteine desulfurase; Provisional; Region: PRK14012
1335916007766	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1335916007767	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1335916007768	catalytic residue [active]
1335916007769	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
1335916007770	Rrf2 family protein; Region: rrf2_super; TIGR00738
1335916007771	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
1335916007772	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1335916007773	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1335916007774	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1335916007775	active site
1335916007776	dimerization interface [polypeptide binding]; other site
1335916007777	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1335916007778	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1335916007779	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
1335916007780	PRD domain; Region: PRD; pfam00874
1335916007781	PRD domain; Region: PRD; pfam00874
1335916007782	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1335916007783	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916007784	putative substrate translocation pore; other site
1335916007785	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1335916007786	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916007787	The C-terminal substrate binding domain of LysR-type transcriptional regulator HcaR in involved in 3-phenylpropionic acid catabolism, contains the type2 periplasmic binding fold; Region: PBP2_HcaR; cd08450
1335916007788	putative dimerization interface [polypeptide binding]; other site
1335916007789	putative substrate binding pocket [chemical binding]; other site
1335916007790	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1335916007791	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916007792	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1335916007793	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
1335916007794	iron-sulfur cluster [ion binding]; other site
1335916007795	[2Fe-2S] cluster binding site [ion binding]; other site
1335916007796	C-terminal catalytic domain of the oxygenase alpha subunit of naphthalene 1,2-dioxygenase (NDO) and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_NDO-like; cd08881
1335916007797	beta subunit interface [polypeptide binding]; other site
1335916007798	alpha subunit interface [polypeptide binding]; other site
1335916007799	active site
1335916007800	substrate binding site [chemical binding]; other site
1335916007801	Fe binding site [ion binding]; other site
1335916007802	Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667
1335916007803	inter-subunit interface; other site
1335916007804	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
1335916007805	[2Fe-2S] cluster binding site [ion binding]; other site
1335916007806	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Provisional; Region: PRK06200
1335916007807	cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)-like, classical (c) SDRs; Region: BphB-like_SDR_c; cd05348
1335916007808	NAD binding site [chemical binding]; other site
1335916007809	active site
1335916007810	phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754
1335916007811	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916007812	Predicted membrane protein [Function unknown]; Region: COG2259
1335916007813	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
1335916007814	active site
1335916007815	catalytic residues [active]
1335916007816	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1335916007817	L-threonine dehydrogenase (TDH)-like; Region: THR_DH_like; cd08239
1335916007818	putative NAD(P) binding site [chemical binding]; other site
1335916007819	catalytic Zn binding site [ion binding]; other site
1335916007820	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1335916007821	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1335916007822	TM-ABC transporter signature motif; other site
1335916007823	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1335916007824	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1335916007825	Walker A/P-loop; other site
1335916007826	ATP binding site [chemical binding]; other site
1335916007827	Q-loop/lid; other site
1335916007828	ABC transporter signature motif; other site
1335916007829	Walker B; other site
1335916007830	D-loop; other site
1335916007831	H-loop/switch region; other site
1335916007832	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1335916007833	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1335916007834	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
1335916007835	ligand binding site [chemical binding]; other site
1335916007836	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1335916007837	TPR motif; other site
1335916007838	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1335916007839	binding surface
1335916007840	TPR repeat; Region: TPR_11; pfam13414
1335916007841	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1335916007842	TPR motif; other site
1335916007843	binding surface
1335916007844	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
1335916007845	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1335916007846	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1335916007847	nucleotide binding site [chemical binding]; other site
1335916007848	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1335916007849	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1335916007850	dimer interface [polypeptide binding]; other site
1335916007851	active site
1335916007852	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1335916007853	folate binding site [chemical binding]; other site
1335916007854	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1335916007855	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1335916007856	heme-binding site [chemical binding]; other site
1335916007857	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1335916007858	FAD binding pocket [chemical binding]; other site
1335916007859	FAD binding motif [chemical binding]; other site
1335916007860	phosphate binding motif [ion binding]; other site
1335916007861	beta-alpha-beta structure motif; other site
1335916007862	NAD binding pocket [chemical binding]; other site
1335916007863	Heme binding  pocket [chemical binding]; other site
1335916007864	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1335916007865	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1335916007866	response regulator GlrR; Provisional; Region: PRK15115
1335916007867	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916007868	active site
1335916007869	phosphorylation site [posttranslational modification]
1335916007870	intermolecular recognition site; other site
1335916007871	dimerization interface [polypeptide binding]; other site
1335916007872	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916007873	Walker A motif; other site
1335916007874	ATP binding site [chemical binding]; other site
1335916007875	Walker B motif; other site
1335916007876	arginine finger; other site
1335916007877	hypothetical protein; Provisional; Region: PRK10722
1335916007878	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1335916007879	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916007880	dimer interface [polypeptide binding]; other site
1335916007881	phosphorylation site [posttranslational modification]
1335916007882	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916007883	ATP binding site [chemical binding]; other site
1335916007884	Mg2+ binding site [ion binding]; other site
1335916007885	G-X-G motif; other site
1335916007886	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1335916007887	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1335916007888	dimerization interface [polypeptide binding]; other site
1335916007889	ATP binding site [chemical binding]; other site
1335916007890	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
1335916007891	dimerization interface [polypeptide binding]; other site
1335916007892	ATP binding site [chemical binding]; other site
1335916007893	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1335916007894	putative active site [active]
1335916007895	catalytic triad [active]
1335916007896	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1335916007897	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916007898	substrate binding pocket [chemical binding]; other site
1335916007899	membrane-bound complex binding site; other site
1335916007900	hinge residues; other site
1335916007901	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1335916007902	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1335916007903	catalytic residue [active]
1335916007904	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1335916007905	nucleoside/Zn binding site; other site
1335916007906	dimer interface [polypeptide binding]; other site
1335916007907	catalytic motif [active]
1335916007908	hypothetical protein; Provisional; Region: PRK11590
1335916007909	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1335916007910	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1335916007911	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
1335916007912	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1335916007913	putative active site [active]
1335916007914	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1335916007915	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
1335916007916	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1335916007917	active site
1335916007918	hydrophilic channel; other site
1335916007919	dimerization interface [polypeptide binding]; other site
1335916007920	catalytic residues [active]
1335916007921	active site lid [active]
1335916007922	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1335916007923	Recombination protein O N terminal; Region: RecO_N; pfam11967
1335916007924	Recombination protein O C terminal; Region: RecO_C; pfam02565
1335916007925	GTPase Era; Reviewed; Region: era; PRK00089
1335916007926	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1335916007927	G1 box; other site
1335916007928	GTP/Mg2+ binding site [chemical binding]; other site
1335916007929	Switch I region; other site
1335916007930	G2 box; other site
1335916007931	Switch II region; other site
1335916007932	G3 box; other site
1335916007933	G4 box; other site
1335916007934	G5 box; other site
1335916007935	KH domain; Region: KH_2; pfam07650
1335916007936	ribonuclease III; Reviewed; Region: rnc; PRK00102
1335916007937	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1335916007938	dimerization interface [polypeptide binding]; other site
1335916007939	active site
1335916007940	metal binding site [ion binding]; metal-binding site
1335916007941	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1335916007942	dsRNA binding site [nucleotide binding]; other site
1335916007943	signal peptidase I; Provisional; Region: PRK10861
1335916007944	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1335916007945	Catalytic site [active]
1335916007946	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1335916007947	GTP-binding protein LepA; Provisional; Region: PRK05433
1335916007948	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1335916007949	G1 box; other site
1335916007950	putative GEF interaction site [polypeptide binding]; other site
1335916007951	GTP/Mg2+ binding site [chemical binding]; other site
1335916007952	Switch I region; other site
1335916007953	G2 box; other site
1335916007954	G3 box; other site
1335916007955	Switch II region; other site
1335916007956	G4 box; other site
1335916007957	G5 box; other site
1335916007958	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1335916007959	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1335916007960	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1335916007961	SoxR reducing system protein RseC; Provisional; Region: PRK10862
1335916007962	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
1335916007963	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1335916007964	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
1335916007965	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1335916007966	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1335916007967	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
1335916007968	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1335916007969	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1335916007970	DNA binding residues [nucleotide binding]
1335916007971	L-aspartate oxidase; Provisional; Region: PRK09077
1335916007972	L-aspartate oxidase; Provisional; Region: PRK06175
1335916007973	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1335916007974	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1335916007975	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1335916007976	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1335916007977	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1335916007978	ATP binding site [chemical binding]; other site
1335916007979	Mg++ binding site [ion binding]; other site
1335916007980	motif III; other site
1335916007981	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1335916007982	nucleotide binding region [chemical binding]; other site
1335916007983	ATP-binding site [chemical binding]; other site
1335916007984	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1335916007985	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916007986	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1335916007987	dimerization interface [polypeptide binding]; other site
1335916007988	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
1335916007989	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1335916007990	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1335916007991	ligand binding site [chemical binding]; other site
1335916007992	active site
1335916007993	UGI interface [polypeptide binding]; other site
1335916007994	catalytic site [active]
1335916007995	putative methyltransferase; Provisional; Region: PRK10864
1335916007996	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1335916007997	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1335916007998	thioredoxin 2; Provisional; Region: PRK10996
1335916007999	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
1335916008000	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1335916008001	catalytic residues [active]
1335916008002	Uncharacterized conserved protein [Function unknown]; Region: COG3148
1335916008003	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1335916008004	CoA binding domain; Region: CoA_binding_2; pfam13380
1335916008005	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1335916008006	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1335916008007	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1335916008008	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1335916008009	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1335916008010	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1335916008011	domain interface [polypeptide binding]; other site
1335916008012	putative active site [active]
1335916008013	catalytic site [active]
1335916008014	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1335916008015	domain interface [polypeptide binding]; other site
1335916008016	putative active site [active]
1335916008017	catalytic site [active]
1335916008018	lipoprotein; Provisional; Region: PRK10759
1335916008019	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1335916008020	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916008021	putative substrate translocation pore; other site
1335916008022	protein disaggregation chaperone; Provisional; Region: PRK10865
1335916008023	Clp amino terminal domain; Region: Clp_N; pfam02861
1335916008024	Clp amino terminal domain; Region: Clp_N; pfam02861
1335916008025	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916008026	Walker A motif; other site
1335916008027	ATP binding site [chemical binding]; other site
1335916008028	Walker B motif; other site
1335916008029	arginine finger; other site
1335916008030	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916008031	Walker A motif; other site
1335916008032	ATP binding site [chemical binding]; other site
1335916008033	Walker B motif; other site
1335916008034	arginine finger; other site
1335916008035	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1335916008036	hypothetical protein; Provisional; Region: PRK10723
1335916008037	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1335916008038	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1335916008039	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1335916008040	RNA binding surface [nucleotide binding]; other site
1335916008041	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1335916008042	active site
1335916008043	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
1335916008044	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
1335916008045	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1335916008046	30S subunit binding site; other site
1335916008047	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1335916008048	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1335916008049	Prephenate dehydratase; Region: PDT; pfam00800
1335916008050	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1335916008051	putative L-Phe binding site [chemical binding]; other site
1335916008052	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1335916008053	chorismate mutase domain of T-protein; Region: CM_T; TIGR01799
1335916008054	prephenate dehydrogenase; Validated; Region: PRK08507
1335916008055	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1335916008056	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1335916008057	lipoprotein; Provisional; Region: PRK11443
1335916008058	Protein of unknown function (DUF2799); Region: DUF2799; pfam10973
1335916008059	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
1335916008060	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
1335916008061	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1335916008062	metal binding site [ion binding]; metal-binding site
1335916008063	active site
1335916008064	I-site; other site
1335916008065	putative outer membrane lipoprotein; Provisional; Region: PRK09967
1335916008066	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1335916008067	ligand binding site [chemical binding]; other site
1335916008068	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1335916008069	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1335916008070	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1335916008071	RimM N-terminal domain; Region: RimM; pfam01782
1335916008072	PRC-barrel domain; Region: PRC; pfam05239
1335916008073	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1335916008074	signal recognition particle protein; Provisional; Region: PRK10867
1335916008075	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1335916008076	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1335916008077	P loop; other site
1335916008078	GTP binding site [chemical binding]; other site
1335916008079	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1335916008080	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
1335916008081	hypothetical protein; Provisional; Region: PRK11573
1335916008082	Domain of unknown function DUF21; Region: DUF21; pfam01595
1335916008083	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1335916008084	Transporter associated domain; Region: CorC_HlyC; smart01091
1335916008085	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1335916008086	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1335916008087	dimer interface [polypeptide binding]; other site
1335916008088	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1335916008089	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1335916008090	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1335916008091	recombination and repair protein; Provisional; Region: PRK10869
1335916008092	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1335916008093	Walker A/P-loop; other site
1335916008094	ATP binding site [chemical binding]; other site
1335916008095	Q-loop/lid; other site
1335916008096	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1335916008097	Q-loop/lid; other site
1335916008098	ABC transporter signature motif; other site
1335916008099	Walker B; other site
1335916008100	D-loop; other site
1335916008101	H-loop/switch region; other site
1335916008102	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
1335916008103	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1335916008104	hypothetical protein; Validated; Region: PRK01777
1335916008105	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1335916008106	putative coenzyme Q binding site [chemical binding]; other site
1335916008107	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1335916008108	SmpB-tmRNA interface; other site
1335916008109	integrase; Provisional; Region: PRK09692
1335916008110	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1335916008111	active site
1335916008112	Int/Topo IB signature motif; other site
1335916008113	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1335916008114	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916008115	ATP binding site [chemical binding]; other site
1335916008116	Mg2+ binding site [ion binding]; other site
1335916008117	G-X-G motif; other site
1335916008118	putative transposase OrfB; Reviewed; Region: PHA02517
1335916008119	HTH-like domain; Region: HTH_21; pfam13276
1335916008120	Integrase core domain; Region: rve; pfam00665
1335916008121	Integrase core domain; Region: rve_2; pfam13333
1335916008122	Transposase; Region: HTH_Tnp_1; cl17663
1335916008123	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1335916008124	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1335916008125	active site
1335916008126	catalytic site [active]
1335916008127	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1335916008128	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
1335916008129	substrate binding pocket [chemical binding]; other site
1335916008130	active site
1335916008131	iron coordination sites [ion binding]; other site
1335916008132	Predicted dehydrogenase [General function prediction only]; Region: COG0579
1335916008133	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1335916008134	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
1335916008135	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1335916008136	tetramerization interface [polypeptide binding]; other site
1335916008137	NAD(P) binding site [chemical binding]; other site
1335916008138	catalytic residues [active]
1335916008139	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
1335916008140	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1335916008141	inhibitor-cofactor binding pocket; inhibition site
1335916008142	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916008143	catalytic residue [active]
1335916008144	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
1335916008145	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
1335916008146	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916008147	DNA-binding site [nucleotide binding]; DNA binding site
1335916008148	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1335916008149	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
1335916008150	bacterial OsmY and nodulation domain; Region: BON; smart00749
1335916008151	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1335916008152	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
1335916008153	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1335916008154	dimerization interface [polypeptide binding]; other site
1335916008155	putative DNA binding site [nucleotide binding]; other site
1335916008156	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1335916008157	putative Zn2+ binding site [ion binding]; other site
1335916008158	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, and similar uncharacterized putative rhodanese-related sulfurtransferases; Region: RHOD_YgaP; cd01527
1335916008159	active site residue [active]
1335916008160	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
1335916008161	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
1335916008162	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1335916008163	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
1335916008164	hypothetical protein; Provisional; Region: PRK10556
1335916008165	hypothetical protein; Provisional; Region: PRK10132
1335916008166	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1335916008167	catalytic residues [active]
1335916008168	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1335916008169	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1335916008170	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1335916008171	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1335916008172	active site
1335916008173	dimer interface [polypeptide binding]; other site
1335916008174	catalytic residues [active]
1335916008175	effector binding site; other site
1335916008176	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1335916008177	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1335916008178	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1335916008179	dimer interface [polypeptide binding]; other site
1335916008180	putative radical transfer pathway; other site
1335916008181	diiron center [ion binding]; other site
1335916008182	tyrosyl radical; other site
1335916008183	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
1335916008184	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1335916008185	Walker A/P-loop; other site
1335916008186	ATP binding site [chemical binding]; other site
1335916008187	Q-loop/lid; other site
1335916008188	ABC transporter signature motif; other site
1335916008189	Walker B; other site
1335916008190	D-loop; other site
1335916008191	H-loop/switch region; other site
1335916008192	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1335916008193	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
1335916008194	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916008195	dimer interface [polypeptide binding]; other site
1335916008196	conserved gate region; other site
1335916008197	putative PBP binding loops; other site
1335916008198	ABC-ATPase subunit interface; other site
1335916008199	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1335916008200	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1335916008201	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1335916008202	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916008203	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1335916008204	putative L-valine exporter; Provisional; Region: PRK10408
1335916008205	transcriptional repressor MprA; Provisional; Region: PRK10870
1335916008206	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1335916008207	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1335916008208	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1335916008209	HlyD family secretion protein; Region: HlyD_3; pfam13437
1335916008210	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1335916008211	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916008212	putative substrate translocation pore; other site
1335916008213	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916008214	RNA ligase; Region: RNA_ligase; pfam09414
1335916008215	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1335916008216	Zn2+ binding site [ion binding]; other site
1335916008217	Mg2+ binding site [ion binding]; other site
1335916008218	AAA domain; Region: AAA_33; pfam13671
1335916008219	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1335916008220	glutamate--cysteine ligase; Provisional; Region: PRK02107
1335916008221	Predicted membrane protein [Function unknown]; Region: COG1238
1335916008222	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
1335916008223	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916008224	motif II; other site
1335916008225	carbon storage regulator; Provisional; Region: PRK01712
1335916008226	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1335916008227	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1335916008228	motif 1; other site
1335916008229	active site
1335916008230	motif 2; other site
1335916008231	motif 3; other site
1335916008232	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1335916008233	DHHA1 domain; Region: DHHA1; pfam02272
1335916008234	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1335916008235	recombinase A; Provisional; Region: recA; PRK09354
1335916008236	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1335916008237	hexamer interface [polypeptide binding]; other site
1335916008238	Walker A motif; other site
1335916008239	ATP binding site [chemical binding]; other site
1335916008240	Walker B motif; other site
1335916008241	hypothetical protein; Validated; Region: PRK03661
1335916008242	Transglycosylase SLT domain; Region: SLT_2; pfam13406
1335916008243	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1335916008244	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1335916008245	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
1335916008246	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1335916008247	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
1335916008248	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1335916008249	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
1335916008250	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
1335916008251	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
1335916008252	putative NAD(P) binding site [chemical binding]; other site
1335916008253	active site
1335916008254	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
1335916008255	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
1335916008256	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1335916008257	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1335916008258	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
1335916008259	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1335916008260	putative active site [active]
1335916008261	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1335916008262	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
1335916008263	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1335916008264	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916008265	Walker A motif; other site
1335916008266	ATP binding site [chemical binding]; other site
1335916008267	Walker B motif; other site
1335916008268	arginine finger; other site
1335916008269	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
1335916008270	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1335916008271	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1335916008272	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1335916008273	iron binding site [ion binding]; other site
1335916008274	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
1335916008275	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916008276	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
1335916008277	Acylphosphatase; Region: Acylphosphatase; pfam00708
1335916008278	HypF finger; Region: zf-HYPF; pfam07503
1335916008279	HypF finger; Region: zf-HYPF; pfam07503
1335916008280	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1335916008281	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1335916008282	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1335916008283	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916008284	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1335916008285	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1335916008286	DNA binding site [nucleotide binding]
1335916008287	domain linker motif; other site
1335916008288	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1335916008289	dimerization interface (closed form) [polypeptide binding]; other site
1335916008290	ligand binding site [chemical binding]; other site
1335916008291	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
1335916008292	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1335916008293	active site turn [active]
1335916008294	phosphorylation site [posttranslational modification]
1335916008295	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1335916008296	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
1335916008297	beta-galactosidase; Region: BGL; TIGR03356
1335916008298	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1335916008299	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1335916008300	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
1335916008301	nickel binding site [ion binding]; other site
1335916008302	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
1335916008303	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
1335916008304	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
1335916008305	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1335916008306	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
1335916008307	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1335916008308	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
1335916008309	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1335916008310	NADH dehydrogenase; Region: NADHdh; cl00469
1335916008311	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
1335916008312	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1335916008313	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1335916008314	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
1335916008315	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1335916008316	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
1335916008317	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
1335916008318	hydrogenase assembly chaperone; Provisional; Region: PRK10409
1335916008319	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1335916008320	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1335916008321	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1335916008322	dimerization interface [polypeptide binding]; other site
1335916008323	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1335916008324	ATP binding site [chemical binding]; other site
1335916008325	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
1335916008326	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1335916008327	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1335916008328	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916008329	Walker A motif; other site
1335916008330	ATP binding site [chemical binding]; other site
1335916008331	Walker B motif; other site
1335916008332	arginine finger; other site
1335916008333	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
1335916008334	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
1335916008335	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1335916008336	MutS domain I; Region: MutS_I; pfam01624
1335916008337	MutS domain II; Region: MutS_II; pfam05188
1335916008338	MutS domain III; Region: MutS_III; pfam05192
1335916008339	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1335916008340	Walker A/P-loop; other site
1335916008341	ATP binding site [chemical binding]; other site
1335916008342	Q-loop/lid; other site
1335916008343	ABC transporter signature motif; other site
1335916008344	Walker B; other site
1335916008345	D-loop; other site
1335916008346	H-loop/switch region; other site
1335916008347	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
1335916008348	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1335916008349	active site
1335916008350	metal binding site [ion binding]; metal-binding site
1335916008351	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1335916008352	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1335916008353	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1335916008354	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1335916008355	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1335916008356	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1335916008357	putative aldolase; Validated; Region: PRK08130
1335916008358	active site
1335916008359	intersubunit interface [polypeptide binding]; other site
1335916008360	Zn2+ binding site [ion binding]; other site
1335916008361	hypothetical protein; Provisional; Region: PRK09989
1335916008362	putative transporter; Provisional; Region: PRK09821
1335916008363	GntP family permease; Region: GntP_permease; pfam02447
1335916008364	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
1335916008365	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
1335916008366	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1335916008367	Flavoprotein; Region: Flavoprotein; pfam02441
1335916008368	MarR family; Region: MarR_2; cl17246
1335916008369	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1335916008370	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
1335916008371	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1335916008372	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1335916008373	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1335916008374	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1335916008375	DNA binding residues [nucleotide binding]
1335916008376	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1335916008377	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1335916008378	Peptidase family M23; Region: Peptidase_M23; pfam01551
1335916008379	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1335916008380	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916008381	S-adenosylmethionine binding site [chemical binding]; other site
1335916008382	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1335916008383	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1335916008384	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1335916008385	Permutation of conserved domain; other site
1335916008386	active site
1335916008387	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1335916008388	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1335916008389	homotrimer interaction site [polypeptide binding]; other site
1335916008390	zinc binding site [ion binding]; other site
1335916008391	CDP-binding sites; other site
1335916008392	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1335916008393	substrate binding site; other site
1335916008394	dimer interface; other site
1335916008395	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1335916008396	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1335916008397	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
1335916008398	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1335916008399	ligand-binding site [chemical binding]; other site
1335916008400	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1335916008401	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1335916008402	CysD dimerization site [polypeptide binding]; other site
1335916008403	G1 box; other site
1335916008404	putative GEF interaction site [polypeptide binding]; other site
1335916008405	GTP/Mg2+ binding site [chemical binding]; other site
1335916008406	Switch I region; other site
1335916008407	G2 box; other site
1335916008408	G3 box; other site
1335916008409	Switch II region; other site
1335916008410	G4 box; other site
1335916008411	G5 box; other site
1335916008412	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1335916008413	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1335916008414	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1335916008415	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1335916008416	Active Sites [active]
1335916008417	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
1335916008418	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1335916008419	metal binding site [ion binding]; metal-binding site
1335916008420	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
1335916008421	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
1335916008422	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09664
1335916008423	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
1335916008424	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
1335916008425	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
1335916008426	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cl09719
1335916008427	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
1335916008428	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
1335916008429	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
1335916008430	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1335916008431	Hok/gef family; Region: HOK_GEF; pfam01848
1335916008432	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1335916008433	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1335916008434	Active Sites [active]
1335916008435	sulfite reductase subunit beta; Provisional; Region: PRK13504
1335916008436	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1335916008437	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1335916008438	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1335916008439	Flavodoxin; Region: Flavodoxin_1; pfam00258
1335916008440	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1335916008441	FAD binding pocket [chemical binding]; other site
1335916008442	FAD binding motif [chemical binding]; other site
1335916008443	catalytic residues [active]
1335916008444	NAD binding pocket [chemical binding]; other site
1335916008445	phosphate binding motif [ion binding]; other site
1335916008446	beta-alpha-beta structure motif; other site
1335916008447	6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a...; Region: PTPS; cd00470
1335916008448	homohexamer interface [polypeptide binding]; other site
1335916008449	putative substrate stabilizing pore; other site
1335916008450	pterin binding site; other site
1335916008451	putative oxidoreductase FixC; Provisional; Region: PRK10157
1335916008452	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1335916008453	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
1335916008454	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1335916008455	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
1335916008456	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1335916008457	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1335916008458	Ligand binding site [chemical binding]; other site
1335916008459	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1335916008460	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
1335916008461	benzoate transport; Region: 2A0115; TIGR00895
1335916008462	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916008463	putative substrate translocation pore; other site
1335916008464	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1335916008465	FAD binding domain; Region: FAD_binding_4; pfam01565
1335916008466	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
1335916008467	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1335916008468	NADP binding site [chemical binding]; other site
1335916008469	homodimer interface [polypeptide binding]; other site
1335916008470	active site
1335916008471	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1335916008472	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1335916008473	nucleotide binding site [chemical binding]; other site
1335916008474	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1335916008475	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1335916008476	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
1335916008477	Repair protein; Region: Repair_PSII; pfam04536
1335916008478	enolase; Provisional; Region: eno; PRK00077
1335916008479	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1335916008480	dimer interface [polypeptide binding]; other site
1335916008481	metal binding site [ion binding]; metal-binding site
1335916008482	substrate binding pocket [chemical binding]; other site
1335916008483	CTP synthetase; Validated; Region: pyrG; PRK05380
1335916008484	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1335916008485	Catalytic site [active]
1335916008486	active site
1335916008487	UTP binding site [chemical binding]; other site
1335916008488	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1335916008489	active site
1335916008490	putative oxyanion hole; other site
1335916008491	catalytic triad [active]
1335916008492	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1335916008493	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1335916008494	homodimer interface [polypeptide binding]; other site
1335916008495	metal binding site [ion binding]; metal-binding site
1335916008496	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1335916008497	homodimer interface [polypeptide binding]; other site
1335916008498	active site
1335916008499	putative chemical substrate binding site [chemical binding]; other site
1335916008500	metal binding site [ion binding]; metal-binding site
1335916008501	toxin MazF; Provisional; Region: PRK09907
1335916008502	antitoxin MazE; Provisional; Region: PRK09798
1335916008503	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1335916008504	HD domain; Region: HD_4; pfam13328
1335916008505	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1335916008506	synthetase active site [active]
1335916008507	NTP binding site [chemical binding]; other site
1335916008508	metal binding site [ion binding]; metal-binding site
1335916008509	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1335916008510	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1335916008511	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
1335916008512	TRAM domain; Region: TRAM; pfam01938
1335916008513	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916008514	S-adenosylmethionine binding site [chemical binding]; other site
1335916008515	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1335916008516	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1335916008517	active site
1335916008518	tetramer interface [polypeptide binding]; other site
1335916008519	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1335916008520	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1335916008521	active site
1335916008522	tetramer interface [polypeptide binding]; other site
1335916008523	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916008524	D-galactonate transporter; Region: 2A0114; TIGR00893
1335916008525	putative substrate translocation pore; other site
1335916008526	flavodoxin; Provisional; Region: PRK08105
1335916008527	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1335916008528	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
1335916008529	probable active site [active]
1335916008530	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
1335916008531	SecY interacting protein Syd; Provisional; Region: PRK04968
1335916008532	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1335916008533	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1335916008534	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1335916008535	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1335916008536	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1335916008537	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1335916008538	serine transporter; Region: stp; TIGR00814
1335916008539	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1335916008540	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1335916008541	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1335916008542	flap endonuclease-like protein; Provisional; Region: PRK09482
1335916008543	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1335916008544	active site
1335916008545	metal binding site 1 [ion binding]; metal-binding site
1335916008546	putative 5' ssDNA interaction site; other site
1335916008547	metal binding site 3; metal-binding site
1335916008548	metal binding site 2 [ion binding]; metal-binding site
1335916008549	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1335916008550	putative DNA binding site [nucleotide binding]; other site
1335916008551	putative metal binding site [ion binding]; other site
1335916008552	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
1335916008553	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1335916008554	dimer interface [polypeptide binding]; other site
1335916008555	active site
1335916008556	metal binding site [ion binding]; metal-binding site
1335916008557	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1335916008558	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1335916008559	intersubunit interface [polypeptide binding]; other site
1335916008560	active site
1335916008561	Zn2+ binding site [ion binding]; other site
1335916008562	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1335916008563	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916008564	putative substrate translocation pore; other site
1335916008565	L-fuculokinase; Provisional; Region: PRK10331
1335916008566	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1335916008567	nucleotide binding site [chemical binding]; other site
1335916008568	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
1335916008569	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
1335916008570	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1335916008571	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1335916008572	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1335916008573	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1335916008574	hypothetical protein; Provisional; Region: PRK10873
1335916008575	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1335916008576	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916008577	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1335916008578	dimerization interface [polypeptide binding]; other site
1335916008579	substrate binding pocket [chemical binding]; other site
1335916008580	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1335916008581	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1335916008582	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1335916008583	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1335916008584	catalytic residue [active]
1335916008585	CsdA-binding activator; Provisional; Region: PRK15019
1335916008586	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
1335916008587	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1335916008588	putative ATP binding site [chemical binding]; other site
1335916008589	putative substrate interface [chemical binding]; other site
1335916008590	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1335916008591	MltA specific insert domain; Region: MltA; pfam03562
1335916008592	3D domain; Region: 3D; pfam06725
1335916008593	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1335916008594	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
1335916008595	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1335916008596	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
1335916008597	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1335916008598	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
1335916008599	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1335916008600	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1335916008601	ligand binding site [chemical binding]; other site
1335916008602	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1335916008603	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1335916008604	Clp amino terminal domain; Region: Clp_N; pfam02861
1335916008605	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916008606	Walker A motif; other site
1335916008607	ATP binding site [chemical binding]; other site
1335916008608	Walker B motif; other site
1335916008609	arginine finger; other site
1335916008610	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916008611	Walker A motif; other site
1335916008612	ATP binding site [chemical binding]; other site
1335916008613	Walker B motif; other site
1335916008614	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1335916008615	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
1335916008616	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1335916008617	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1335916008618	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1335916008619	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253
1335916008620	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
1335916008621	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1335916008622	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1335916008623	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1335916008624	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253
1335916008625	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
1335916008626	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1335916008627	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
1335916008628	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1335916008629	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
1335916008630	PAAR motif; Region: PAAR_motif; pfam05488
1335916008631	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
1335916008632	Integrase core domain; Region: rve; pfam00665
1335916008633	DDE domain; Region: DDE_Tnp_IS240; pfam13610
1335916008634	Integrase core domain; Region: rve_3; pfam13683
1335916008635	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1335916008636	Transposase; Region: HTH_Tnp_1; cl17663
1335916008637	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1335916008638	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1335916008639	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
1335916008640	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
1335916008641	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
1335916008642	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1335916008643	ImpA domain protein; Region: DUF3702; pfam12486
1335916008644	ROS/MUCR transcriptional regulator protein; Region: ROS_MUCR; pfam05443
1335916008645	AMIN domain; Region: AMIN; pfam11741
1335916008646	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1335916008647	active site
1335916008648	metal binding site [ion binding]; metal-binding site
1335916008649	N-acetylglutamate synthase; Validated; Region: PRK05279
1335916008650	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1335916008651	putative feedback inhibition sensing region; other site
1335916008652	putative nucleotide binding site [chemical binding]; other site
1335916008653	putative substrate binding site [chemical binding]; other site
1335916008654	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1335916008655	Coenzyme A binding pocket [chemical binding]; other site
1335916008656	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
1335916008657	AAA domain; Region: AAA_30; pfam13604
1335916008658	Family description; Region: UvrD_C_2; pfam13538
1335916008659	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1335916008660	protease3; Provisional; Region: PRK15101
1335916008661	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1335916008662	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1335916008663	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1335916008664	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1335916008665	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
1335916008666	hypothetical protein; Provisional; Region: PRK10332
1335916008667	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
1335916008668	hypothetical protein; Provisional; Region: PRK11521
1335916008669	hypothetical protein; Provisional; Region: PRK10557
1335916008670	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1335916008671	hypothetical protein; Provisional; Region: PRK10506
1335916008672	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1335916008673	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1335916008674	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1335916008675	dimerization interface [polypeptide binding]; other site
1335916008676	active site
1335916008677	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
1335916008678	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
1335916008679	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1335916008680	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1335916008681	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1335916008682	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1335916008683	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1335916008684	putative active site [active]
1335916008685	Ap4A binding site [chemical binding]; other site
1335916008686	nudix motif; other site
1335916008687	putative metal binding site [ion binding]; other site
1335916008688	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
1335916008689	putative DNA-binding cleft [nucleotide binding]; other site
1335916008690	putative DNA clevage site; other site
1335916008691	molecular lever; other site
1335916008692	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1335916008693	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1335916008694	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1335916008695	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1335916008696	active site
1335916008697	catalytic tetrad [active]
1335916008698	lysophospholipid transporter LplT; Provisional; Region: PRK11195
1335916008699	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916008700	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
1335916008701	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1335916008702	putative acyl-acceptor binding pocket; other site
1335916008703	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1335916008704	acyl-activating enzyme (AAE) consensus motif; other site
1335916008705	putative AMP binding site [chemical binding]; other site
1335916008706	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
1335916008707	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1335916008708	DNA binding site [nucleotide binding]
1335916008709	domain linker motif; other site
1335916008710	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1335916008711	dimerization interface (closed form) [polypeptide binding]; other site
1335916008712	ligand binding site [chemical binding]; other site
1335916008713	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1335916008714	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1335916008715	active site
1335916008716	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1335916008717	substrate binding site [chemical binding]; other site
1335916008718	catalytic residues [active]
1335916008719	dimer interface [polypeptide binding]; other site
1335916008720	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1335916008721	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916008722	The C-terminal substrate binding domain of LysR, transcriptional regulator for lysine biosynthesis, contains the type 2 periplasmic binding fold; Region: PBP2_LysR; cd08456
1335916008723	putative dimerization interface [polypeptide binding]; other site
1335916008724	putative racemase; Provisional; Region: PRK10200
1335916008725	aspartate racemase; Region: asp_race; TIGR00035
1335916008726	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1335916008727	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916008728	putative substrate translocation pore; other site
1335916008729	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916008730	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1335916008731	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1335916008732	NADP binding site [chemical binding]; other site
1335916008733	homodimer interface [polypeptide binding]; other site
1335916008734	active site
1335916008735	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
1335916008736	putative acyltransferase; Provisional; Region: PRK05790
1335916008737	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1335916008738	dimer interface [polypeptide binding]; other site
1335916008739	active site
1335916008740	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1335916008741	serine transporter; Region: stp; TIGR00814
1335916008742	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
1335916008743	DNA binding residues [nucleotide binding]
1335916008744	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1335916008745	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
1335916008746	hyperosmolarity resistance protein Ebh, N-terminal domain; Region: hyperosmo_Ebh; TIGR04264
1335916008747	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
1335916008748	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1335916008749	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1335916008750	transcriptional regulator; Provisional; Region: PRK11906
1335916008751	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1335916008752	DNA binding site [nucleotide binding]
1335916008753	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1335916008754	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916008755	DNA binding residues [nucleotide binding]
1335916008756	dimerization interface [polypeptide binding]; other site
1335916008757	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1335916008758	invasion protein OrgB; Provisional; Region: PRK15322
1335916008759	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
1335916008760	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
1335916008761	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327; cl12363
1335916008762	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
1335916008763	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916008764	DNA binding residues [nucleotide binding]
1335916008765	InvH outer membrane lipoprotein; Region: InvH; pfam04741
1335916008766	type III secretion system protein SpaS; Validated; Region: PRK08156
1335916008767	type III secretion system protein SpaS; Validated; Region: PRK08156
1335916008768	type III secretion protein SpaR/YscT/HrcT; Region: fliR_like_III; TIGR01401
1335916008769	Bacterial export proteins, family 3; Region: Bac_export_3; cl00867
1335916008770	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
1335916008771	Surface presentation of antigens (SPOA); Region: SpoA; cl00819
1335916008772	type III secretion system protein SpaO; Validated; Region: PRK08158
1335916008773	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
1335916008774	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1335916008775	Peptidase family M23; Region: Peptidase_M23; pfam01551
1335916008776	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
1335916008777	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
1335916008778	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1335916008779	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
1335916008780	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
1335916008781	xanthine dehydrogenase subunit XdhC; Provisional; Region: PRK09908
1335916008782	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1335916008783	catalytic loop [active]
1335916008784	iron binding site [ion binding]; other site
1335916008785	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1335916008786	GAF domain; Region: GAF; cl17456
1335916008787	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
1335916008788	PAS domain; Region: PAS; smart00091
1335916008789	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916008790	Walker A motif; other site
1335916008791	ATP binding site [chemical binding]; other site
1335916008792	Walker B motif; other site
1335916008793	arginine finger; other site
1335916008794	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1335916008795	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
1335916008796	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1335916008797	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1335916008798	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1335916008799	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
1335916008800	catalytic residue [active]
1335916008801	peptidase; Reviewed; Region: PRK13004
1335916008802	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
1335916008803	putative metal binding site [ion binding]; other site
1335916008804	putative dimer interface [polypeptide binding]; other site
1335916008805	D-hydantoinase; Region: D-hydantoinase; TIGR02033
1335916008806	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
1335916008807	tetramer interface [polypeptide binding]; other site
1335916008808	active site
1335916008809	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1335916008810	carbamate kinase; Reviewed; Region: PRK12686
1335916008811	putative substrate binding site [chemical binding]; other site
1335916008812	homodimer interface [polypeptide binding]; other site
1335916008813	nucleotide binding site [chemical binding]; other site
1335916008814	nucleotide binding site [chemical binding]; other site
1335916008815	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
1335916008816	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
1335916008817	Ligand binding site; other site
1335916008818	metal-binding site
1335916008819	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
1335916008820	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1335916008821	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1335916008822	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916008823	putative selenium metabolism protein SsnA; Region: Se_ssnA; TIGR03314
1335916008824	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
1335916008825	active site
1335916008826	putative substrate binding pocket [chemical binding]; other site
1335916008827	probable selenate reductase, FAD-binding subunit; Region: Se_sel_red_FAD; TIGR03312
1335916008828	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
1335916008829	putative hypoxanthine oxidase; Provisional; Region: PRK09800
1335916008830	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1335916008831	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
1335916008832	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1335916008833	uracil-xanthine permease; Region: ncs2; TIGR00801
1335916008834	guanine deaminase; Provisional; Region: PRK09228
1335916008835	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
1335916008836	active site
1335916008837	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1335916008838	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1335916008839	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12809
1335916008840	4Fe-4S binding domain; Region: Fer4; pfam00037
1335916008841	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1335916008842	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916008843	xanthine permease; Region: pbuX; TIGR03173
1335916008844	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
1335916008845	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1335916008846	active site
1335916008847	metal binding site [ion binding]; metal-binding site
1335916008848	nudix motif; other site
1335916008849	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1335916008850	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1335916008851	dimer interface [polypeptide binding]; other site
1335916008852	putative anticodon binding site; other site
1335916008853	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1335916008854	motif 1; other site
1335916008855	active site
1335916008856	motif 2; other site
1335916008857	motif 3; other site
1335916008858	peptide chain release factor 2; Provisional; Region: PRK08787
1335916008859	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1335916008860	RF-1 domain; Region: RF-1; pfam00472
1335916008861	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
1335916008862	DHH family; Region: DHH; pfam01368
1335916008863	DHHA1 domain; Region: DHHA1; pfam02272
1335916008864	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1335916008865	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1335916008866	dimerization domain [polypeptide binding]; other site
1335916008867	dimer interface [polypeptide binding]; other site
1335916008868	catalytic residues [active]
1335916008869	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1335916008870	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1335916008871	active site
1335916008872	Int/Topo IB signature motif; other site
1335916008873	flavodoxin FldB; Provisional; Region: PRK12359
1335916008874	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
1335916008875	hypothetical protein; Provisional; Region: PRK10878
1335916008876	putative global regulator; Reviewed; Region: PRK09559
1335916008877	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1335916008878	hemolysin; Provisional; Region: PRK15087
1335916008879	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1335916008880	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
1335916008881	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
1335916008882	beta-galactosidase; Region: BGL; TIGR03356
1335916008883	putative NAD(P)-binding oxidoreductase; Provisional; Region: PRK09730
1335916008884	classical (c) SDRs; Region: SDR_c; cd05233
1335916008885	NAD(P) binding site [chemical binding]; other site
1335916008886	active site
1335916008887	glycine dehydrogenase; Provisional; Region: PRK05367
1335916008888	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1335916008889	tetramer interface [polypeptide binding]; other site
1335916008890	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916008891	catalytic residue [active]
1335916008892	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1335916008893	tetramer interface [polypeptide binding]; other site
1335916008894	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916008895	catalytic residue [active]
1335916008896	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1335916008897	lipoyl attachment site [posttranslational modification]; other site
1335916008898	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1335916008899	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1335916008900	oxidoreductase; Provisional; Region: PRK08013
1335916008901	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1335916008902	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1335916008903	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1335916008904	proline aminopeptidase P II; Provisional; Region: PRK10879
1335916008905	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
1335916008906	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1335916008907	active site
1335916008908	hypothetical protein; Reviewed; Region: PRK01736
1335916008909	Z-ring-associated protein; Provisional; Region: PRK10972
1335916008910	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
1335916008911	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1335916008912	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1335916008913	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1335916008914	ligand binding site [chemical binding]; other site
1335916008915	NAD binding site [chemical binding]; other site
1335916008916	tetramer interface [polypeptide binding]; other site
1335916008917	catalytic site [active]
1335916008918	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1335916008919	L-serine binding site [chemical binding]; other site
1335916008920	ACT domain interface; other site
1335916008921	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1335916008922	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1335916008923	active site
1335916008924	dimer interface [polypeptide binding]; other site
1335916008925	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1335916008926	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1335916008927	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916008928	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1335916008929	putative dimerization interface [polypeptide binding]; other site
1335916008930	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
1335916008931	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
1335916008932	active site
1335916008933	substrate binding site [chemical binding]; other site
1335916008934	coenzyme B12 binding site [chemical binding]; other site
1335916008935	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
1335916008936	B12 binding site [chemical binding]; other site
1335916008937	cobalt ligand [ion binding]; other site
1335916008938	membrane ATPase/protein kinase; Provisional; Region: PRK09435
1335916008939	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
1335916008940	Walker A; other site
1335916008941	methylmalonyl-CoA decarboxylase; Provisional; Region: PRK11423
1335916008942	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1335916008943	substrate binding site [chemical binding]; other site
1335916008944	oxyanion hole (OAH) forming residues; other site
1335916008945	trimer interface [polypeptide binding]; other site
1335916008946	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
1335916008947	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
1335916008948	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1335916008949	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916008950	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1335916008951	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1335916008952	dimerization interface [polypeptide binding]; other site
1335916008953	Uncharacterized conserved protein [Function unknown]; Region: COG2968
1335916008954	oxidative stress defense protein; Provisional; Region: PRK11087
1335916008955	arginine exporter protein; Provisional; Region: PRK09304
1335916008956	mechanosensitive channel MscS; Provisional; Region: PRK10334
1335916008957	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1335916008958	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1335916008959	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1335916008960	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1335916008961	active site
1335916008962	intersubunit interface [polypeptide binding]; other site
1335916008963	zinc binding site [ion binding]; other site
1335916008964	Na+ binding site [ion binding]; other site
1335916008965	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1335916008966	Phosphoglycerate kinase; Region: PGK; pfam00162
1335916008967	substrate binding site [chemical binding]; other site
1335916008968	hinge regions; other site
1335916008969	ADP binding site [chemical binding]; other site
1335916008970	catalytic site [active]
1335916008971	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
1335916008972	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1335916008973	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1335916008974	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
1335916008975	trimer interface [polypeptide binding]; other site
1335916008976	putative Zn binding site [ion binding]; other site
1335916008977	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1335916008978	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1335916008979	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1335916008980	Walker A/P-loop; other site
1335916008981	ATP binding site [chemical binding]; other site
1335916008982	Q-loop/lid; other site
1335916008983	ABC transporter signature motif; other site
1335916008984	Walker B; other site
1335916008985	D-loop; other site
1335916008986	H-loop/switch region; other site
1335916008987	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1335916008988	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1335916008989	Walker A/P-loop; other site
1335916008990	ATP binding site [chemical binding]; other site
1335916008991	Q-loop/lid; other site
1335916008992	ABC transporter signature motif; other site
1335916008993	Walker B; other site
1335916008994	D-loop; other site
1335916008995	H-loop/switch region; other site
1335916008996	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1335916008997	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
1335916008998	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1335916008999	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1335916009000	putative active site [active]
1335916009001	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
1335916009002	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1335916009003	putative NAD(P) binding site [chemical binding]; other site
1335916009004	catalytic Zn binding site [ion binding]; other site
1335916009005	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
1335916009006	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1335916009007	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1335916009008	active site
1335916009009	P-loop; other site
1335916009010	phosphorylation site [posttranslational modification]
1335916009011	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1335916009012	active site
1335916009013	phosphorylation site [posttranslational modification]
1335916009014	transketolase; Reviewed; Region: PRK12753
1335916009015	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1335916009016	TPP-binding site [chemical binding]; other site
1335916009017	dimer interface [polypeptide binding]; other site
1335916009018	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1335916009019	PYR/PP interface [polypeptide binding]; other site
1335916009020	dimer interface [polypeptide binding]; other site
1335916009021	TPP binding site [chemical binding]; other site
1335916009022	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1335916009023	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1335916009024	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
1335916009025	agmatinase; Region: agmatinase; TIGR01230
1335916009026	oligomer interface [polypeptide binding]; other site
1335916009027	putative active site [active]
1335916009028	Mn binding site [ion binding]; other site
1335916009029	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
1335916009030	peptidylprolyl isomerase; Provisional; Region: prsA; PRK04405
1335916009031	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
1335916009032	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1335916009033	dimer interface [polypeptide binding]; other site
1335916009034	active site
1335916009035	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1335916009036	catalytic residues [active]
1335916009037	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1335916009038	Virulence promoting factor; Region: YqgB; pfam11036
1335916009039	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1335916009040	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1335916009041	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1335916009042	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1335916009043	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1335916009044	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916009045	putative substrate translocation pore; other site
1335916009046	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916009047	hypothetical protein; Provisional; Region: PRK04860
1335916009048	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1335916009049	DNA-specific endonuclease I; Provisional; Region: PRK15137
1335916009050	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
1335916009051	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1335916009052	RNA methyltransferase, RsmE family; Region: TIGR00046
1335916009053	glutathione synthetase; Provisional; Region: PRK05246
1335916009054	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1335916009055	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1335916009056	hypothetical protein; Validated; Region: PRK00228
1335916009057	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1335916009058	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
1335916009059	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
1335916009060	Walker A motif; other site
1335916009061	ATP binding site [chemical binding]; other site
1335916009062	Walker B motif; other site
1335916009063	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1335916009064	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1335916009065	catalytic residue [active]
1335916009066	YGGT family; Region: YGGT; pfam02325
1335916009067	YGGT family; Region: YGGT; pfam02325
1335916009068	hypothetical protein; Validated; Region: PRK05090
1335916009069	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1335916009070	active site
1335916009071	dimerization interface [polypeptide binding]; other site
1335916009072	HemN family oxidoreductase; Provisional; Region: PRK05660
1335916009073	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916009074	FeS/SAM binding site; other site
1335916009075	HemN C-terminal domain; Region: HemN_C; pfam06969
1335916009076	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
1335916009077	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
1335916009078	homodimer interface [polypeptide binding]; other site
1335916009079	active site
1335916009080	hypothetical protein; Provisional; Region: PRK10626
1335916009081	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
1335916009082	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1335916009083	hypothetical protein; Provisional; Region: PRK11702
1335916009084	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
1335916009085	adenine DNA glycosylase; Provisional; Region: PRK10880
1335916009086	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1335916009087	minor groove reading motif; other site
1335916009088	helix-hairpin-helix signature motif; other site
1335916009089	substrate binding pocket [chemical binding]; other site
1335916009090	active site
1335916009091	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
1335916009092	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1335916009093	DNA binding and oxoG recognition site [nucleotide binding]
1335916009094	oxidative damage protection protein; Provisional; Region: PRK05408
1335916009095	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1335916009096	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1335916009097	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1335916009098	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1335916009099	catalytic residue [active]
1335916009100	nucleoside transporter; Region: 2A0110; TIGR00889
1335916009101	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
1335916009102	putative general secretion pathway protein YghD; Provisional; Region: PRK09731
1335916009103	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
1335916009104	type II secretion system protein J; Region: gspJ; TIGR01711
1335916009105	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
1335916009106	type II secretion system protein I; Region: gspI; TIGR01707
1335916009107	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
1335916009108	Prokaryotic N-terminal methylation motif; Region: N_methyl; pfam07963
1335916009109	Type II transport protein GspH; Region: GspH; pfam12019
1335916009110	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1335916009111	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
1335916009112	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
1335916009113	type II secretion system protein F; Region: GspF; TIGR02120
1335916009114	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1335916009115	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1335916009116	type II secretion system protein E; Region: type_II_gspE; TIGR02533
1335916009117	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1335916009118	Walker A motif; other site
1335916009119	ATP binding site [chemical binding]; other site
1335916009120	Walker B motif; other site
1335916009121	type II secretion system protein D; Region: type_II_gspD; TIGR02517
1335916009122	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1335916009123	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1335916009124	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1335916009125	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1335916009126	putative type II secretion protein GspC; Provisional; Region: PRK09681
1335916009127	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
1335916009128	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1335916009129	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1335916009130	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
1335916009131	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1335916009132	Domain of unknown function (DUF4092); Region: DUF4092; pfam13322
1335916009133	Peptidase M60-like family; Region: M60-like; pfam13402
1335916009134	glycolate transporter; Provisional; Region: PRK09695
1335916009135	L-lactate permease; Region: Lactate_perm; cl00701
1335916009136	Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate...; Region: malate_synt_G; cd00728
1335916009137	active site
1335916009138	hypothetical protein; Provisional; Region: PRK09732
1335916009139	glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274
1335916009140	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1335916009141	Cysteine-rich domain; Region: CCG; pfam02754
1335916009142	Cysteine-rich domain; Region: CCG; pfam02754
1335916009143	glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282
1335916009144	FAD binding domain; Region: FAD_binding_4; pfam01565
1335916009145	glycolate oxidase subunit GlcD; Provisional; Region: PRK11230
1335916009146	FAD binding domain; Region: FAD_binding_4; pfam01565
1335916009147	acyl-CoA synthetase; Validated; Region: PRK09192
1335916009148	Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931
1335916009149	acyl-activating enzyme (AAE) consensus motif; other site
1335916009150	active site
1335916009151	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1335916009152	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1335916009153	NAD(P) binding site [chemical binding]; other site
1335916009154	active site
1335916009155	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1335916009156	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1335916009157	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1335916009158	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1335916009159	catalytic residue [active]
1335916009160	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
1335916009161	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1335916009162	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1335916009163	Predicted permeases [General function prediction only]; Region: COG0795
1335916009164	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; pfam09695
1335916009165	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1335916009166	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1335916009167	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1335916009168	Thymidylate kinase; Region: Thymidylate_kin; pfam02223
1335916009169	active site
1335916009170	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1335916009171	thymidylate kinase; Validated; Region: tmk; PRK00698
1335916009172	TMP-binding site; other site
1335916009173	ATP-binding site [chemical binding]; other site
1335916009174	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1335916009175	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1335916009176	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
1335916009177	CHAP domain; Region: CHAP; pfam05257
1335916009178	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1335916009179	putative S-transferase; Provisional; Region: PRK11752
1335916009180	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1335916009181	C-terminal domain interface [polypeptide binding]; other site
1335916009182	GSH binding site (G-site) [chemical binding]; other site
1335916009183	dimer interface [polypeptide binding]; other site
1335916009184	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
1335916009185	dimer interface [polypeptide binding]; other site
1335916009186	N-terminal domain interface [polypeptide binding]; other site
1335916009187	active site
1335916009188	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
1335916009189	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1335916009190	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
1335916009191	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
1335916009192	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1335916009193	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1335916009194	putative substrate-binding site; other site
1335916009195	nickel binding site [ion binding]; other site
1335916009196	hydrogenase 2 large subunit; Provisional; Region: PRK10467
1335916009197	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1335916009198	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
1335916009199	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1335916009200	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
1335916009201	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1335916009202	hydrogenase 2 small subunit; Provisional; Region: PRK10468
1335916009203	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1335916009204	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1335916009205	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
1335916009206	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1335916009207	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1335916009208	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1335916009209	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1335916009210	active site
1335916009211	catalytic tetrad [active]
1335916009212	hypothetical protein; Provisional; Region: PRK05208
1335916009213	oxidoreductase; Provisional; Region: PRK07985
1335916009214	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1335916009215	NAD binding site [chemical binding]; other site
1335916009216	metal binding site [ion binding]; metal-binding site
1335916009217	active site
1335916009218	biopolymer transport protein ExbD; Provisional; Region: PRK11267
1335916009219	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1335916009220	biopolymer transport protein ExbB; Provisional; Region: PRK10414
1335916009221	cystathionine beta-lyase; Provisional; Region: PRK08114
1335916009222	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1335916009223	homodimer interface [polypeptide binding]; other site
1335916009224	substrate-cofactor binding pocket; other site
1335916009225	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916009226	catalytic residue [active]
1335916009227	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1335916009228	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1335916009229	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1335916009230	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1335916009231	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916009232	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916009233	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1335916009234	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1335916009235	active site
1335916009236	catalytic tetrad [active]
1335916009237	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
1335916009238	putative outer membrane lipoprotein; Provisional; Region: PRK09973
1335916009239	hypothetical protein; Provisional; Region: PRK01254
1335916009240	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
1335916009241	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
1335916009242	FtsI repressor; Provisional; Region: PRK10883
1335916009243	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1335916009244	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1335916009245	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
1335916009246	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1335916009247	putative acyl-acceptor binding pocket; other site
1335916009248	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
1335916009249	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1335916009250	CAP-like domain; other site
1335916009251	active site
1335916009252	primary dimer interface [polypeptide binding]; other site
1335916009253	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1335916009254	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
1335916009255	TIGR00156 family protein; Region: TIGR00156
1335916009256	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
1335916009257	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916009258	active site
1335916009259	phosphorylation site [posttranslational modification]
1335916009260	intermolecular recognition site; other site
1335916009261	dimerization interface [polypeptide binding]; other site
1335916009262	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1335916009263	DNA binding site [nucleotide binding]
1335916009264	sensor protein QseC; Provisional; Region: PRK10337
1335916009265	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916009266	dimer interface [polypeptide binding]; other site
1335916009267	phosphorylation site [posttranslational modification]
1335916009268	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916009269	ATP binding site [chemical binding]; other site
1335916009270	Mg2+ binding site [ion binding]; other site
1335916009271	G-X-G motif; other site
1335916009272	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1335916009273	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1335916009274	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
1335916009275	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916009276	ATP binding site [chemical binding]; other site
1335916009277	Mg2+ binding site [ion binding]; other site
1335916009278	G-X-G motif; other site
1335916009279	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1335916009280	anchoring element; other site
1335916009281	dimer interface [polypeptide binding]; other site
1335916009282	ATP binding site [chemical binding]; other site
1335916009283	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1335916009284	active site
1335916009285	metal binding site [ion binding]; metal-binding site
1335916009286	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1335916009287	esterase YqiA; Provisional; Region: PRK11071
1335916009288	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1335916009289	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1335916009290	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1335916009291	active site
1335916009292	metal binding site [ion binding]; metal-binding site
1335916009293	hexamer interface [polypeptide binding]; other site
1335916009294	putative dehydrogenase; Provisional; Region: PRK11039
1335916009295	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1335916009296	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1335916009297	dimer interface [polypeptide binding]; other site
1335916009298	ADP-ribose binding site [chemical binding]; other site
1335916009299	active site
1335916009300	nudix motif; other site
1335916009301	metal binding site [ion binding]; metal-binding site
1335916009302	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
1335916009303	hypothetical protein; Provisional; Region: PRK11653
1335916009304	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1335916009305	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1335916009306	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1335916009307	putative active site [active]
1335916009308	metal binding site [ion binding]; metal-binding site
1335916009309	zinc transporter ZupT; Provisional; Region: PRK04201
1335916009310	ZIP Zinc transporter; Region: Zip; pfam02535
1335916009311	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
1335916009312	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1335916009313	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1335916009314	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
1335916009315	putative fimbrial protein; Provisional; Region: PRK09733
1335916009316	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1335916009317	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1335916009318	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1335916009319	Fimbrial protein; Region: Fimbrial; pfam00419
1335916009320	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
1335916009321	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
1335916009322	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1335916009323	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
1335916009324	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
1335916009325	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1335916009326	putative ribose interaction site [chemical binding]; other site
1335916009327	putative ADP binding site [chemical binding]; other site
1335916009328	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1335916009329	active site
1335916009330	nucleotide binding site [chemical binding]; other site
1335916009331	HIGH motif; other site
1335916009332	KMSKS motif; other site
1335916009333	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1335916009334	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
1335916009335	putative active site [active]
1335916009336	putative metal binding residues [ion binding]; other site
1335916009337	signature motif; other site
1335916009338	putative triphosphate binding site [ion binding]; other site
1335916009339	CHAD domain; Region: CHAD; pfam05235
1335916009340	SH3 domain-containing protein; Provisional; Region: PRK10884
1335916009341	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1335916009342	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1335916009343	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1335916009344	active site
1335916009345	NTP binding site [chemical binding]; other site
1335916009346	metal binding triad [ion binding]; metal-binding site
1335916009347	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1335916009348	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1335916009349	Zn2+ binding site [ion binding]; other site
1335916009350	Mg2+ binding site [ion binding]; other site
1335916009351	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1335916009352	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1335916009353	homooctamer interface [polypeptide binding]; other site
1335916009354	active site
1335916009355	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1335916009356	transcriptional activator TtdR; Provisional; Region: PRK09801
1335916009357	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916009358	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
1335916009359	putative effector binding pocket; other site
1335916009360	putative dimerization interface [polypeptide binding]; other site
1335916009361	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
1335916009362	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
1335916009363	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1335916009364	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1335916009365	transmembrane helices; other site
1335916009366	UGMP family protein; Validated; Region: PRK09604
1335916009367	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1335916009368	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1335916009369	DNA primase; Validated; Region: dnaG; PRK05667
1335916009370	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1335916009371	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1335916009372	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1335916009373	active site
1335916009374	metal binding site [ion binding]; metal-binding site
1335916009375	interdomain interaction site; other site
1335916009376	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1335916009377	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1335916009378	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1335916009379	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1335916009380	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1335916009381	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1335916009382	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1335916009383	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1335916009384	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1335916009385	DNA binding residues [nucleotide binding]
1335916009386	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
1335916009387	active site
1335916009388	SUMO-1 interface [polypeptide binding]; other site
1335916009389	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1335916009390	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1335916009391	FAD binding pocket [chemical binding]; other site
1335916009392	FAD binding motif [chemical binding]; other site
1335916009393	phosphate binding motif [ion binding]; other site
1335916009394	NAD binding pocket [chemical binding]; other site
1335916009395	Predicted transcriptional regulators [Transcription]; Region: COG1695
1335916009396	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1335916009397	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1335916009398	PAS fold; Region: PAS_3; pfam08447
1335916009399	putative active site [active]
1335916009400	heme pocket [chemical binding]; other site
1335916009401	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1335916009402	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1335916009403	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1335916009404	dimer interface [polypeptide binding]; other site
1335916009405	putative CheW interface [polypeptide binding]; other site
1335916009406	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
1335916009407	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1335916009408	inhibitor-cofactor binding pocket; inhibition site
1335916009409	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916009410	catalytic residue [active]
1335916009411	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
1335916009412	dimer interface [polypeptide binding]; other site
1335916009413	putative tRNA-binding site [nucleotide binding]; other site
1335916009414	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
1335916009415	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1335916009416	DNA binding site [nucleotide binding]
1335916009417	domain linker motif; other site
1335916009418	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
1335916009419	putative dimerization interface [polypeptide binding]; other site
1335916009420	putative ligand binding site [chemical binding]; other site
1335916009421	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
1335916009422	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1335916009423	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1335916009424	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1335916009425	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
1335916009426	Domain of unknown function (DUF386); Region: DUF386; cl01047
1335916009427	Domain of unknown function (DUF386); Region: DUF386; cl01047
1335916009428	inner membrane transporter YjeM; Provisional; Region: PRK15238
1335916009429	alpha-glucosidase; Provisional; Region: PRK10137
1335916009430	Protein of unknown function, DUF608; Region: DUF608; pfam04685
1335916009431	Trehalase; Region: Trehalase; cl17346
1335916009432	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1335916009433	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
1335916009434	active site
1335916009435	FMN binding site [chemical binding]; other site
1335916009436	2,4-decadienoyl-CoA binding site; other site
1335916009437	catalytic residue [active]
1335916009438	4Fe-4S cluster binding site [ion binding]; other site
1335916009439	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
1335916009440	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1335916009441	non-specific DNA binding site [nucleotide binding]; other site
1335916009442	salt bridge; other site
1335916009443	sequence-specific DNA binding site [nucleotide binding]; other site
1335916009444	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
1335916009445	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916009446	S-adenosylmethionine binding site [chemical binding]; other site
1335916009447	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1335916009448	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1335916009449	putative active site [active]
1335916009450	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1335916009451	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1335916009452	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1335916009453	serine/threonine transporter SstT; Provisional; Region: PRK13628
1335916009454	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1335916009455	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
1335916009456	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1335916009457	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1335916009458	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1335916009459	Glucuronate isomerase; Region: UxaC; pfam02614
1335916009460	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1335916009461	D-galactonate transporter; Region: 2A0114; TIGR00893
1335916009462	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916009463	putative substrate translocation pore; other site
1335916009464	CblD like pilus biogenesis initiator; Region: CblD; cl06460
1335916009465	CS1 type fimbrial major subunit; Region: Fimbrial_CS1; pfam04449
1335916009466	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1335916009467	putative fimbrial protein TcfA; Provisional; Region: PRK15308
1335916009468	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
1335916009469	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916009470	DNA-binding site [nucleotide binding]; DNA binding site
1335916009471	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1335916009472	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1335916009473	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1335916009474	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
1335916009475	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1335916009476	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
1335916009477	Predicted membrane protein [Function unknown]; Region: COG5393
1335916009478	YqjK-like protein; Region: YqjK; pfam13997
1335916009479	Predicted membrane protein [Function unknown]; Region: COG2259
1335916009480	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
1335916009481	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
1335916009482	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
1335916009483	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
1335916009484	putative dimer interface [polypeptide binding]; other site
1335916009485	N-terminal domain interface [polypeptide binding]; other site
1335916009486	putative substrate binding pocket (H-site) [chemical binding]; other site
1335916009487	Predicted membrane protein [Function unknown]; Region: COG3152
1335916009488	Protein of unknown function (DUF805); Region: DUF805; pfam05656
1335916009489	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916009490	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1335916009491	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1335916009492	dimerization interface [polypeptide binding]; other site
1335916009493	Pirin-related protein [General function prediction only]; Region: COG1741
1335916009494	Pirin; Region: Pirin; pfam02678
1335916009495	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
1335916009496	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1335916009497	serine transporter; Region: stp; TIGR00814
1335916009498	L-serine dehydratase TdcG; Provisional; Region: PRK15040
1335916009499	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1335916009500	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1335916009501	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1335916009502	homotrimer interaction site [polypeptide binding]; other site
1335916009503	putative active site [active]
1335916009504	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1335916009505	Pyruvate formate lyase 1; Region: PFL1; cd01678
1335916009506	coenzyme A binding site [chemical binding]; other site
1335916009507	active site
1335916009508	catalytic residues [active]
1335916009509	glycine loop; other site
1335916009510	propionate/acetate kinase; Provisional; Region: PRK12379
1335916009511	Acetokinase family; Region: Acetate_kinase; cl17229
1335916009512	threonine/serine transporter TdcC; Provisional; Region: PRK13629
1335916009513	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1335916009514	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1335916009515	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1335916009516	tetramer interface [polypeptide binding]; other site
1335916009517	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916009518	catalytic residue [active]
1335916009519	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
1335916009520	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916009521	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
1335916009522	putative substrate binding pocket [chemical binding]; other site
1335916009523	putative dimerization interface [polypeptide binding]; other site
1335916009524	hypothetical protein; Provisional; Region: PRK09716
1335916009525	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1335916009526	glycerate kinase I; Provisional; Region: PRK10342
1335916009527	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
1335916009528	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1335916009529	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
1335916009530	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916009531	D-galactonate transporter; Region: 2A0114; TIGR00893
1335916009532	putative substrate translocation pore; other site
1335916009533	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1335916009534	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1335916009535	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1335916009536	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
1335916009537	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
1335916009538	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1335916009539	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1335916009540	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
1335916009541	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1335916009542	active site
1335916009543	phosphorylation site [posttranslational modification]
1335916009544	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1335916009545	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1335916009546	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1335916009547	active pocket/dimerization site; other site
1335916009548	active site
1335916009549	phosphorylation site [posttranslational modification]
1335916009550	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1335916009551	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1335916009552	active site
1335916009553	dimer interface [polypeptide binding]; other site
1335916009554	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
1335916009555	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1335916009556	dimer interface [polypeptide binding]; other site
1335916009557	active site
1335916009558	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
1335916009559	putative active site [active]
1335916009560	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cd00453
1335916009561	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1335916009562	active site
1335916009563	intersubunit interface [polypeptide binding]; other site
1335916009564	zinc binding site [ion binding]; other site
1335916009565	Na+ binding site [ion binding]; other site
1335916009566	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1335916009567	active site
1335916009568	phosphorylation site [posttranslational modification]
1335916009569	PTS system N-acetylgalactosamine-specific transporter subunit IIC; Provisional; Region: PRK09757
1335916009570	PTS system N-acetylgalactosamine-specific transporter subunit IID; Provisional; Region: PRK09855
1335916009571	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1335916009572	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1335916009573	active site
1335916009574	trimer interface [polypeptide binding]; other site
1335916009575	allosteric site; other site
1335916009576	active site lid [active]
1335916009577	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1335916009578	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1335916009579	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1335916009580	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1335916009581	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1335916009582	PapC N-terminal domain; Region: PapC_N; pfam13954
1335916009583	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1335916009584	PapC C-terminal domain; Region: PapC_C; pfam13953
1335916009585	Fimbrial protein; Region: Fimbrial; pfam00419
1335916009586	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
1335916009587	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1335916009588	putative SAM binding site [chemical binding]; other site
1335916009589	putative homodimer interface [polypeptide binding]; other site
1335916009590	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1335916009591	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
1335916009592	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1335916009593	putative ligand binding site [chemical binding]; other site
1335916009594	TIGR00252 family protein; Region: TIGR00252
1335916009595	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1335916009596	dimer interface [polypeptide binding]; other site
1335916009597	active site
1335916009598	outer membrane lipoprotein; Provisional; Region: PRK11023
1335916009599	BON domain; Region: BON; pfam04972
1335916009600	BON domain; Region: BON; pfam04972
1335916009601	Predicted permease; Region: DUF318; pfam03773
1335916009602	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
1335916009603	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1335916009604	NAD binding site [chemical binding]; other site
1335916009605	active site
1335916009606	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1335916009607	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1335916009608	proposed catalytic triad [active]
1335916009609	conserved cys residue [active]
1335916009610	hypothetical protein; Provisional; Region: PRK03467
1335916009611	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1335916009612	GIY-YIG motif/motif A; other site
1335916009613	putative active site [active]
1335916009614	putative metal binding site [ion binding]; other site
1335916009615	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1335916009616	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1335916009617	Coenzyme A binding pocket [chemical binding]; other site
1335916009618	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
1335916009619	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1335916009620	Peptidase family U32; Region: Peptidase_U32; pfam01136
1335916009621	putative protease; Provisional; Region: PRK15447
1335916009622	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1335916009623	hypothetical protein; Provisional; Region: PRK10508
1335916009624	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1335916009625	tryptophan permease; Provisional; Region: PRK10483
1335916009626	aromatic amino acid transport protein; Region: araaP; TIGR00837
1335916009627	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1335916009628	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1335916009629	ATP binding site [chemical binding]; other site
1335916009630	Mg++ binding site [ion binding]; other site
1335916009631	motif III; other site
1335916009632	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1335916009633	nucleotide binding region [chemical binding]; other site
1335916009634	ATP-binding site [chemical binding]; other site
1335916009635	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1335916009636	putative RNA binding site [nucleotide binding]; other site
1335916009637	lipoprotein NlpI; Provisional; Region: PRK11189
1335916009638	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1335916009639	binding surface
1335916009640	TPR motif; other site
1335916009641	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1335916009642	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1335916009643	RNase E interface [polypeptide binding]; other site
1335916009644	trimer interface [polypeptide binding]; other site
1335916009645	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1335916009646	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1335916009647	RNase E interface [polypeptide binding]; other site
1335916009648	trimer interface [polypeptide binding]; other site
1335916009649	active site
1335916009650	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1335916009651	putative nucleic acid binding region [nucleotide binding]; other site
1335916009652	G-X-X-G motif; other site
1335916009653	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1335916009654	RNA binding site [nucleotide binding]; other site
1335916009655	domain interface; other site
1335916009656	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1335916009657	16S/18S rRNA binding site [nucleotide binding]; other site
1335916009658	S13e-L30e interaction site [polypeptide binding]; other site
1335916009659	25S rRNA binding site [nucleotide binding]; other site
1335916009660	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1335916009661	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1335916009662	RNA binding site [nucleotide binding]; other site
1335916009663	active site
1335916009664	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1335916009665	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1335916009666	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1335916009667	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1335916009668	translation initiation factor IF-2; Region: IF-2; TIGR00487
1335916009669	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1335916009670	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1335916009671	G1 box; other site
1335916009672	putative GEF interaction site [polypeptide binding]; other site
1335916009673	GTP/Mg2+ binding site [chemical binding]; other site
1335916009674	Switch I region; other site
1335916009675	G2 box; other site
1335916009676	G3 box; other site
1335916009677	Switch II region; other site
1335916009678	G4 box; other site
1335916009679	G5 box; other site
1335916009680	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1335916009681	Translation-initiation factor 2; Region: IF-2; pfam11987
1335916009682	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1335916009683	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1335916009684	NusA N-terminal domain; Region: NusA_N; pfam08529
1335916009685	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1335916009686	RNA binding site [nucleotide binding]; other site
1335916009687	homodimer interface [polypeptide binding]; other site
1335916009688	NusA-like KH domain; Region: KH_5; pfam13184
1335916009689	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1335916009690	G-X-X-G motif; other site
1335916009691	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1335916009692	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1335916009693	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1335916009694	Sm and related proteins; Region: Sm_like; cl00259
1335916009695	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1335916009696	putative oligomer interface [polypeptide binding]; other site
1335916009697	putative RNA binding site [nucleotide binding]; other site
1335916009698	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
1335916009699	ANP binding site [chemical binding]; other site
1335916009700	Substrate Binding Site II [chemical binding]; other site
1335916009701	Substrate Binding Site I [chemical binding]; other site
1335916009702	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1335916009703	Sulfatase; Region: Sulfatase; pfam00884
1335916009704	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1335916009705	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1335916009706	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1335916009707	active site
1335916009708	substrate binding site [chemical binding]; other site
1335916009709	metal binding site [ion binding]; metal-binding site
1335916009710	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1335916009711	dihydropteroate synthase; Region: DHPS; TIGR01496
1335916009712	substrate binding pocket [chemical binding]; other site
1335916009713	dimer interface [polypeptide binding]; other site
1335916009714	inhibitor binding site; inhibition site
1335916009715	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1335916009716	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916009717	Walker A motif; other site
1335916009718	ATP binding site [chemical binding]; other site
1335916009719	Walker B motif; other site
1335916009720	arginine finger; other site
1335916009721	Peptidase family M41; Region: Peptidase_M41; pfam01434
1335916009722	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1335916009723	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916009724	S-adenosylmethionine binding site [chemical binding]; other site
1335916009725	RNA-binding protein YhbY; Provisional; Region: PRK10343
1335916009726	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1335916009727	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1335916009728	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1335916009729	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1335916009730	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1335916009731	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1335916009732	GTP1/OBG; Region: GTP1_OBG; pfam01018
1335916009733	Obg GTPase; Region: Obg; cd01898
1335916009734	G1 box; other site
1335916009735	GTP/Mg2+ binding site [chemical binding]; other site
1335916009736	Switch I region; other site
1335916009737	G2 box; other site
1335916009738	G3 box; other site
1335916009739	Switch II region; other site
1335916009740	G4 box; other site
1335916009741	G5 box; other site
1335916009742	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1335916009743	EamA-like transporter family; Region: EamA; pfam00892
1335916009744	EamA-like transporter family; Region: EamA; pfam00892
1335916009745	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1335916009746	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1335916009747	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1335916009748	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1335916009749	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1335916009750	substrate binding pocket [chemical binding]; other site
1335916009751	chain length determination region; other site
1335916009752	substrate-Mg2+ binding site; other site
1335916009753	catalytic residues [active]
1335916009754	aspartate-rich region 1; other site
1335916009755	active site lid residues [active]
1335916009756	aspartate-rich region 2; other site
1335916009757	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
1335916009758	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1335916009759	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1335916009760	hinge; other site
1335916009761	active site
1335916009762	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1335916009763	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1335916009764	anti sigma factor interaction site; other site
1335916009765	regulatory phosphorylation site [posttranslational modification]; other site
1335916009766	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
1335916009767	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1335916009768	mce related protein; Region: MCE; pfam02470
1335916009769	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1335916009770	conserved hypothetical integral membrane protein; Region: TIGR00056
1335916009771	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1335916009772	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1335916009773	Walker A/P-loop; other site
1335916009774	ATP binding site [chemical binding]; other site
1335916009775	Q-loop/lid; other site
1335916009776	ABC transporter signature motif; other site
1335916009777	Walker B; other site
1335916009778	D-loop; other site
1335916009779	H-loop/switch region; other site
1335916009780	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
1335916009781	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1335916009782	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1335916009783	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1335916009784	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1335916009785	putative active site [active]
1335916009786	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1335916009787	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
1335916009788	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1335916009789	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
1335916009790	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1335916009791	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
1335916009792	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
1335916009793	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
1335916009794	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1335916009795	Walker A/P-loop; other site
1335916009796	ATP binding site [chemical binding]; other site
1335916009797	Q-loop/lid; other site
1335916009798	ABC transporter signature motif; other site
1335916009799	Walker B; other site
1335916009800	D-loop; other site
1335916009801	H-loop/switch region; other site
1335916009802	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1335916009803	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1335916009804	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1335916009805	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1335916009806	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1335916009807	30S subunit binding site; other site
1335916009808	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1335916009809	active site
1335916009810	phosphorylation site [posttranslational modification]
1335916009811	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
1335916009812	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1335916009813	dimerization domain swap beta strand [polypeptide binding]; other site
1335916009814	regulatory protein interface [polypeptide binding]; other site
1335916009815	active site
1335916009816	regulatory phosphorylation site [posttranslational modification]; other site
1335916009817	hypothetical protein; Provisional; Region: PRK10345
1335916009818	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1335916009819	Transglycosylase; Region: Transgly; cl17702
1335916009820	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
1335916009821	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
1335916009822	conserved cys residue [active]
1335916009823	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
1335916009824	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1335916009825	putative active site [active]
1335916009826	heme pocket [chemical binding]; other site
1335916009827	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916009828	dimer interface [polypeptide binding]; other site
1335916009829	phosphorylation site [posttranslational modification]
1335916009830	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916009831	ATP binding site [chemical binding]; other site
1335916009832	Mg2+ binding site [ion binding]; other site
1335916009833	G-X-G motif; other site
1335916009834	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916009835	active site
1335916009836	phosphorylation site [posttranslational modification]
1335916009837	intermolecular recognition site; other site
1335916009838	dimerization interface [polypeptide binding]; other site
1335916009839	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1335916009840	putative binding surface; other site
1335916009841	active site
1335916009842	radical SAM protein, TIGR01212 family; Region: TIGR01212
1335916009843	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916009844	FeS/SAM binding site; other site
1335916009845	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1335916009846	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1335916009847	active site
1335916009848	dimer interface [polypeptide binding]; other site
1335916009849	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1335916009850	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1335916009851	active site
1335916009852	FMN binding site [chemical binding]; other site
1335916009853	substrate binding site [chemical binding]; other site
1335916009854	3Fe-4S cluster binding site [ion binding]; other site
1335916009855	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1335916009856	domain interface; other site
1335916009857	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
1335916009858	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1335916009859	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916009860	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1335916009861	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1335916009862	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1335916009863	N-acetylmannosamine kinase; Provisional; Region: PRK05082
1335916009864	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1335916009865	nucleotide binding site [chemical binding]; other site
1335916009866	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1335916009867	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
1335916009868	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1335916009869	putative active site cavity [active]
1335916009870	putative sialic acid transporter; Provisional; Region: PRK03893
1335916009871	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916009872	putative substrate translocation pore; other site
1335916009873	N-acetylneuraminate lyase; Region: nanA; TIGR00683
1335916009874	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
1335916009875	inhibitor site; inhibition site
1335916009876	active site
1335916009877	dimer interface [polypeptide binding]; other site
1335916009878	catalytic residue [active]
1335916009879	transcriptional regulator NanR; Provisional; Region: PRK03837
1335916009880	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916009881	DNA-binding site [nucleotide binding]; DNA binding site
1335916009882	FCD domain; Region: FCD; pfam07729
1335916009883	putative cryptic C4-dicarboxylate transporter DcuD; Provisional; Region: PRK09804
1335916009884	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1335916009885	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
1335916009886	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1335916009887	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1335916009888	C-terminal domain interface [polypeptide binding]; other site
1335916009889	putative GSH binding site (G-site) [chemical binding]; other site
1335916009890	dimer interface [polypeptide binding]; other site
1335916009891	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1335916009892	dimer interface [polypeptide binding]; other site
1335916009893	N-terminal domain interface [polypeptide binding]; other site
1335916009894	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1335916009895	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1335916009896	23S rRNA interface [nucleotide binding]; other site
1335916009897	L3 interface [polypeptide binding]; other site
1335916009898	Predicted ATPase [General function prediction only]; Region: COG1485
1335916009899	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
1335916009900	hypothetical protein; Provisional; Region: PRK11677
1335916009901	serine endoprotease; Provisional; Region: PRK10139
1335916009902	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1335916009903	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1335916009904	protein binding site [polypeptide binding]; other site
1335916009905	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1335916009906	serine endoprotease; Provisional; Region: PRK10898
1335916009907	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1335916009908	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1335916009909	malate dehydrogenase; Provisional; Region: PRK05086
1335916009910	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1335916009911	NAD binding site [chemical binding]; other site
1335916009912	dimerization interface [polypeptide binding]; other site
1335916009913	Substrate binding site [chemical binding]; other site
1335916009914	arginine repressor; Provisional; Region: PRK05066
1335916009915	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1335916009916	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1335916009917	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1335916009918	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
1335916009919	RNAase interaction site [polypeptide binding]; other site
1335916009920	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
1335916009921	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1335916009922	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
1335916009923	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1335916009924	HlyD family secretion protein; Region: HlyD_3; pfam13437
1335916009925	efflux system membrane protein; Provisional; Region: PRK11594
1335916009926	transcriptional regulator; Provisional; Region: PRK10632
1335916009927	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916009928	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1335916009929	putative effector binding pocket; other site
1335916009930	dimerization interface [polypeptide binding]; other site
1335916009931	protease TldD; Provisional; Region: tldD; PRK10735
1335916009932	hypothetical protein; Provisional; Region: PRK10899
1335916009933	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1335916009934	ribonuclease G; Provisional; Region: PRK11712
1335916009935	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1335916009936	homodimer interface [polypeptide binding]; other site
1335916009937	oligonucleotide binding site [chemical binding]; other site
1335916009938	Maf-like protein; Region: Maf; pfam02545
1335916009939	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1335916009940	active site
1335916009941	dimer interface [polypeptide binding]; other site
1335916009942	rod shape-determining protein MreD; Provisional; Region: PRK11060
1335916009943	rod shape-determining protein MreC; Region: mreC; TIGR00219
1335916009944	rod shape-determining protein MreC; Region: MreC; pfam04085
1335916009945	rod shape-determining protein MreB; Provisional; Region: PRK13927
1335916009946	MreB and similar proteins; Region: MreB_like; cd10225
1335916009947	nucleotide binding site [chemical binding]; other site
1335916009948	Mg binding site [ion binding]; other site
1335916009949	putative protofilament interaction site [polypeptide binding]; other site
1335916009950	RodZ interaction site [polypeptide binding]; other site
1335916009951	regulatory protein CsrD; Provisional; Region: PRK11059
1335916009952	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1335916009953	metal binding site [ion binding]; metal-binding site
1335916009954	active site
1335916009955	I-site; other site
1335916009956	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1335916009957	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
1335916009958	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1335916009959	NADP binding site [chemical binding]; other site
1335916009960	dimer interface [polypeptide binding]; other site
1335916009961	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1335916009962	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1335916009963	carboxyltransferase (CT) interaction site; other site
1335916009964	biotinylation site [posttranslational modification]; other site
1335916009965	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1335916009966	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1335916009967	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1335916009968	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1335916009969	hypothetical protein; Provisional; Region: PRK10633
1335916009970	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
1335916009971	Na binding site [ion binding]; other site
1335916009972	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
1335916009973	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1335916009974	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
1335916009975	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1335916009976	FMN binding site [chemical binding]; other site
1335916009977	active site
1335916009978	catalytic residues [active]
1335916009979	substrate binding site [chemical binding]; other site
1335916009980	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1335916009981	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1335916009982	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1335916009983	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916009984	DNA methylase; Region: N6_N4_Mtase; pfam01555
1335916009985	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
1335916009986	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
1335916009987	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1335916009988	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1335916009989	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1335916009990	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1335916009991	HlyD family secretion protein; Region: HlyD_3; pfam13437
1335916009992	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1335916009993	Protein export membrane protein; Region: SecD_SecF; cl14618
1335916009994	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1335916009995	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1335916009996	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916009997	substrate binding pocket [chemical binding]; other site
1335916009998	membrane-bound complex binding site; other site
1335916009999	hinge residues; other site
1335916010000	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
1335916010001	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916010002	conserved gate region; other site
1335916010003	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916010004	dimer interface [polypeptide binding]; other site
1335916010005	conserved gate region; other site
1335916010006	putative PBP binding loops; other site
1335916010007	ABC-ATPase subunit interface; other site
1335916010008	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1335916010009	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916010010	dimer interface [polypeptide binding]; other site
1335916010011	conserved gate region; other site
1335916010012	putative PBP binding loops; other site
1335916010013	ABC-ATPase subunit interface; other site
1335916010014	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1335916010015	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1335916010016	Walker A/P-loop; other site
1335916010017	ATP binding site [chemical binding]; other site
1335916010018	Q-loop/lid; other site
1335916010019	ABC transporter signature motif; other site
1335916010020	Walker B; other site
1335916010021	D-loop; other site
1335916010022	H-loop/switch region; other site
1335916010023	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1335916010024	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1335916010025	trimer interface [polypeptide binding]; other site
1335916010026	putative metal binding site [ion binding]; other site
1335916010027	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
1335916010028	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
1335916010029	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1335916010030	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1335916010031	shikimate binding site; other site
1335916010032	NAD(P) binding site [chemical binding]; other site
1335916010033	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
1335916010034	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1335916010035	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1335916010036	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1335916010037	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1335916010038	hypothetical protein; Validated; Region: PRK03430
1335916010039	hypothetical protein; Provisional; Region: PRK10736
1335916010040	DNA protecting protein DprA; Region: dprA; TIGR00732
1335916010041	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1335916010042	active site
1335916010043	catalytic residues [active]
1335916010044	metal binding site [ion binding]; metal-binding site
1335916010045	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1335916010046	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1335916010047	putative active site [active]
1335916010048	substrate binding site [chemical binding]; other site
1335916010049	putative cosubstrate binding site; other site
1335916010050	catalytic site [active]
1335916010051	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1335916010052	substrate binding site [chemical binding]; other site
1335916010053	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1335916010054	putative RNA binding site [nucleotide binding]; other site
1335916010055	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1335916010056	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916010057	S-adenosylmethionine binding site [chemical binding]; other site
1335916010058	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1335916010059	TrkA-N domain; Region: TrkA_N; pfam02254
1335916010060	TrkA-C domain; Region: TrkA_C; pfam02080
1335916010061	TrkA-N domain; Region: TrkA_N; pfam02254
1335916010062	TrkA-C domain; Region: TrkA_C; pfam02080
1335916010063	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1335916010064	Large-conductance mechanosensitive channel, MscL; Region: MscL; pfam01741
1335916010065	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
1335916010066	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
1335916010067	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
1335916010068	DNA binding residues [nucleotide binding]
1335916010069	dimer interface [polypeptide binding]; other site
1335916010070	metal binding site [ion binding]; metal-binding site
1335916010071	hypothetical protein; Provisional; Region: PRK10203
1335916010072	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1335916010073	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1335916010074	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1335916010075	alphaNTD homodimer interface [polypeptide binding]; other site
1335916010076	alphaNTD - beta interaction site [polypeptide binding]; other site
1335916010077	alphaNTD - beta' interaction site [polypeptide binding]; other site
1335916010078	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1335916010079	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1335916010080	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1335916010081	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1335916010082	RNA binding surface [nucleotide binding]; other site
1335916010083	30S ribosomal protein S11; Validated; Region: PRK05309
1335916010084	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1335916010085	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1335916010086	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
1335916010087	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1335916010088	SecY translocase; Region: SecY; pfam00344
1335916010089	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1335916010090	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1335916010091	23S rRNA binding site [nucleotide binding]; other site
1335916010092	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1335916010093	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1335916010094	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1335916010095	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1335916010096	23S rRNA interface [nucleotide binding]; other site
1335916010097	5S rRNA interface [nucleotide binding]; other site
1335916010098	L27 interface [polypeptide binding]; other site
1335916010099	L5 interface [polypeptide binding]; other site
1335916010100	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1335916010101	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1335916010102	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1335916010103	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1335916010104	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1335916010105	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1335916010106	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1335916010107	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1335916010108	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1335916010109	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1335916010110	RNA binding site [nucleotide binding]; other site
1335916010111	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1335916010112	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1335916010113	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1335916010114	23S rRNA interface [nucleotide binding]; other site
1335916010115	putative translocon interaction site; other site
1335916010116	signal recognition particle (SRP54) interaction site; other site
1335916010117	L23 interface [polypeptide binding]; other site
1335916010118	trigger factor interaction site; other site
1335916010119	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1335916010120	23S rRNA interface [nucleotide binding]; other site
1335916010121	5S rRNA interface [nucleotide binding]; other site
1335916010122	putative antibiotic binding site [chemical binding]; other site
1335916010123	L25 interface [polypeptide binding]; other site
1335916010124	L27 interface [polypeptide binding]; other site
1335916010125	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1335916010126	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1335916010127	G-X-X-G motif; other site
1335916010128	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1335916010129	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1335916010130	protein-rRNA interface [nucleotide binding]; other site
1335916010131	putative translocon binding site; other site
1335916010132	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1335916010133	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1335916010134	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1335916010135	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1335916010136	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1335916010137	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1335916010138	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
1335916010139	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1335916010140	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1335916010141	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1335916010142	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
1335916010143	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
1335916010144	heme binding site [chemical binding]; other site
1335916010145	ferroxidase pore; other site
1335916010146	ferroxidase diiron center [ion binding]; other site
1335916010147	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
1335916010148	elongation factor Tu; Reviewed; Region: PRK00049
1335916010149	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1335916010150	G1 box; other site
1335916010151	GEF interaction site [polypeptide binding]; other site
1335916010152	GTP/Mg2+ binding site [chemical binding]; other site
1335916010153	Switch I region; other site
1335916010154	G2 box; other site
1335916010155	G3 box; other site
1335916010156	Switch II region; other site
1335916010157	G4 box; other site
1335916010158	G5 box; other site
1335916010159	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1335916010160	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1335916010161	Antibiotic Binding Site [chemical binding]; other site
1335916010162	elongation factor G; Reviewed; Region: PRK00007
1335916010163	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1335916010164	G1 box; other site
1335916010165	putative GEF interaction site [polypeptide binding]; other site
1335916010166	GTP/Mg2+ binding site [chemical binding]; other site
1335916010167	Switch I region; other site
1335916010168	G2 box; other site
1335916010169	G3 box; other site
1335916010170	Switch II region; other site
1335916010171	G4 box; other site
1335916010172	G5 box; other site
1335916010173	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1335916010174	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1335916010175	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1335916010176	30S ribosomal protein S7; Validated; Region: PRK05302
1335916010177	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1335916010178	S17 interaction site [polypeptide binding]; other site
1335916010179	S8 interaction site; other site
1335916010180	16S rRNA interaction site [nucleotide binding]; other site
1335916010181	streptomycin interaction site [chemical binding]; other site
1335916010182	23S rRNA interaction site [nucleotide binding]; other site
1335916010183	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1335916010184	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
1335916010185	sulfur relay protein TusC; Validated; Region: PRK00211
1335916010186	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1335916010187	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1335916010188	YheO-like PAS domain; Region: PAS_6; pfam08348
1335916010189	HTH domain; Region: HTH_22; pfam13309
1335916010190	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
1335916010191	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1335916010192	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1335916010193	phi X174 lysis protein; Provisional; Region: PRK02793
1335916010194	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1335916010195	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1335916010196	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
1335916010197	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1335916010198	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1335916010199	TrkA-N domain; Region: TrkA_N; pfam02254
1335916010200	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
1335916010201	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1335916010202	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916010203	Walker A/P-loop; other site
1335916010204	ATP binding site [chemical binding]; other site
1335916010205	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1335916010206	ABC transporter signature motif; other site
1335916010207	Walker B; other site
1335916010208	D-loop; other site
1335916010209	ABC transporter; Region: ABC_tran_2; pfam12848
1335916010210	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1335916010211	hypothetical protein; Provisional; Region: PRK04966
1335916010212	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
1335916010213	active site
1335916010214	hypothetical protein; Provisional; Region: PRK10738
1335916010215	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1335916010216	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1335916010217	ligand binding site [chemical binding]; other site
1335916010218	flexible hinge region; other site
1335916010219	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1335916010220	putative switch regulator; other site
1335916010221	non-specific DNA interactions [nucleotide binding]; other site
1335916010222	DNA binding site [nucleotide binding]
1335916010223	sequence specific DNA binding site [nucleotide binding]; other site
1335916010224	putative cAMP binding site [chemical binding]; other site
1335916010225	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1335916010226	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1335916010227	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1335916010228	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
1335916010229	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1335916010230	inhibitor-cofactor binding pocket; inhibition site
1335916010231	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916010232	catalytic residue [active]
1335916010233	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1335916010234	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1335916010235	glutamine binding [chemical binding]; other site
1335916010236	catalytic triad [active]
1335916010237	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
1335916010238	cell filamentation protein Fic; Provisional; Region: PRK10347
1335916010239	hypothetical protein; Provisional; Region: PRK10204
1335916010240	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
1335916010241	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1335916010242	substrate binding site [chemical binding]; other site
1335916010243	putative transporter; Provisional; Region: PRK03699
1335916010244	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916010245	putative substrate translocation pore; other site
1335916010246	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1335916010247	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916010248	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1335916010249	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1335916010250	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1335916010251	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1335916010252	nitrite transporter NirC; Provisional; Region: PRK11562
1335916010253	siroheme synthase; Provisional; Region: cysG; PRK10637
1335916010254	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1335916010255	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1335916010256	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1335916010257	active site
1335916010258	SAM binding site [chemical binding]; other site
1335916010259	homodimer interface [polypeptide binding]; other site
1335916010260	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
1335916010261	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
1335916010262	hypothetical protein; Provisional; Region: PHA02764
1335916010263	fructoselysine-6-P-deglycase; Provisional; Region: frlB; PRK11382
1335916010264	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
1335916010265	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1335916010266	dimer interface [polypeptide binding]; other site
1335916010267	active site
1335916010268	fructoselysine 3-epimerase; Provisional; Region: PRK09856
1335916010269	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1335916010270	AP (apurinic/apyrimidinic) site pocket; other site
1335916010271	DNA interaction; other site
1335916010272	Metal-binding active site; metal-binding site
1335916010273	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
1335916010274	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1335916010275	substrate binding site [chemical binding]; other site
1335916010276	ATP binding site [chemical binding]; other site
1335916010277	DNA-binding transcriptional regulator FrlR; Provisional; Region: PRK11402
1335916010278	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916010279	DNA-binding site [nucleotide binding]; DNA binding site
1335916010280	UTRA domain; Region: UTRA; pfam07702
1335916010281	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1335916010282	DNA topoisomerase III, bacteria and conjugative plasmid; Region: topB; TIGR01056
1335916010283	Protein of unknown function; Region: YhfT; pfam10797
1335916010284	Protein of unknown function DUF2620; Region: DUF2620; pfam10941
1335916010285	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1335916010286	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
1335916010287	active site
1335916010288	substrate binding pocket [chemical binding]; other site
1335916010289	homodimer interaction site [polypeptide binding]; other site
1335916010290	putative mutase; Provisional; Region: PRK12383
1335916010291	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; COG1015
1335916010292	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme yhfX; Region: PLPDE_III_yhfX_like; cd06811
1335916010293	dimer interface [polypeptide binding]; other site
1335916010294	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
1335916010295	active site
1335916010296	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1335916010297	substrate binding site [chemical binding]; other site
1335916010298	catalytic residue [active]
1335916010299	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
1335916010300	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1335916010301	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1335916010302	active site
1335916010303	HIGH motif; other site
1335916010304	dimer interface [polypeptide binding]; other site
1335916010305	KMSKS motif; other site
1335916010306	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1335916010307	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916010308	motif II; other site
1335916010309	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1335916010310	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1335916010311	substrate binding site [chemical binding]; other site
1335916010312	hexamer interface [polypeptide binding]; other site
1335916010313	metal binding site [ion binding]; metal-binding site
1335916010314	DNA adenine methylase; Provisional; Region: PRK10904
1335916010315	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
1335916010316	cell division protein DamX; Validated; Region: PRK10905
1335916010317	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1335916010318	active site
1335916010319	dimer interface [polypeptide binding]; other site
1335916010320	metal binding site [ion binding]; metal-binding site
1335916010321	shikimate kinase; Reviewed; Region: aroK; PRK00131
1335916010322	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1335916010323	ADP binding site [chemical binding]; other site
1335916010324	magnesium binding site [ion binding]; other site
1335916010325	putative shikimate binding site; other site
1335916010326	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
1335916010327	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1335916010328	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1335916010329	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
1335916010330	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
1335916010331	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
1335916010332	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1335916010333	Transglycosylase; Region: Transgly; pfam00912
1335916010334	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1335916010335	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1335916010336	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1335916010337	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1335916010338	ADP-ribose binding site [chemical binding]; other site
1335916010339	dimer interface [polypeptide binding]; other site
1335916010340	active site
1335916010341	nudix motif; other site
1335916010342	metal binding site [ion binding]; metal-binding site
1335916010343	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
1335916010344	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1335916010345	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916010346	motif II; other site
1335916010347	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1335916010348	RNA binding surface [nucleotide binding]; other site
1335916010349	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1335916010350	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1335916010351	dimerization interface [polypeptide binding]; other site
1335916010352	domain crossover interface; other site
1335916010353	redox-dependent activation switch; other site
1335916010354	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
1335916010355	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1335916010356	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1335916010357	active site
1335916010358	substrate-binding site [chemical binding]; other site
1335916010359	metal-binding site [ion binding]
1335916010360	ATP binding site [chemical binding]; other site
1335916010361	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
1335916010362	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1335916010363	non-specific DNA binding site [nucleotide binding]; other site
1335916010364	salt bridge; other site
1335916010365	sequence-specific DNA binding site [nucleotide binding]; other site
1335916010366	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
1335916010367	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1335916010368	dimerization interface [polypeptide binding]; other site
1335916010369	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916010370	dimer interface [polypeptide binding]; other site
1335916010371	phosphorylation site [posttranslational modification]
1335916010372	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916010373	ATP binding site [chemical binding]; other site
1335916010374	G-X-G motif; other site
1335916010375	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1335916010376	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916010377	active site
1335916010378	phosphorylation site [posttranslational modification]
1335916010379	intermolecular recognition site; other site
1335916010380	dimerization interface [polypeptide binding]; other site
1335916010381	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1335916010382	DNA binding site [nucleotide binding]
1335916010383	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1335916010384	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1335916010385	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1335916010386	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1335916010387	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1335916010388	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1335916010389	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1335916010390	RNA binding site [nucleotide binding]; other site
1335916010391	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
1335916010392	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
1335916010393	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1335916010394	G1 box; other site
1335916010395	GTP/Mg2+ binding site [chemical binding]; other site
1335916010396	Switch I region; other site
1335916010397	G2 box; other site
1335916010398	G3 box; other site
1335916010399	Switch II region; other site
1335916010400	G4 box; other site
1335916010401	G5 box; other site
1335916010402	Nucleoside recognition; Region: Gate; pfam07670
1335916010403	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1335916010404	Nucleoside recognition; Region: Gate; pfam07670
1335916010405	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
1335916010406	carboxylesterase BioH; Provisional; Region: PRK10349
1335916010407	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
1335916010408	DNA utilization protein GntX; Provisional; Region: PRK11595
1335916010409	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1335916010410	active site
1335916010411	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1335916010412	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1335916010413	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1335916010414	high-affinity gluconate transporter; Provisional; Region: PRK14984
1335916010415	gluconate transporter; Region: gntP; TIGR00791
1335916010416	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1335916010417	4-alpha-glucanotransferase; Region: malQ; TIGR00217
1335916010418	transcriptional regulator MalT; Provisional; Region: PRK04841
1335916010419	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916010420	DNA binding residues [nucleotide binding]
1335916010421	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
1335916010422	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
1335916010423	putative active site [active]
1335916010424	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
1335916010425	hypothetical protein; Reviewed; Region: PRK09588
1335916010426	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
1335916010427	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
1335916010428	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916010429	Walker A motif; other site
1335916010430	ATP binding site [chemical binding]; other site
1335916010431	Walker B motif; other site
1335916010432	arginine finger; other site
1335916010433	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
1335916010434	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1335916010435	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1335916010436	intramembrane serine protease GlpG; Provisional; Region: PRK10907
1335916010437	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
1335916010438	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1335916010439	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1335916010440	active site residue [active]
1335916010441	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
1335916010442	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916010443	hypothetical protein; Provisional; Region: PRK09781; cl08057
1335916010444	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
1335916010445	glycogen phosphorylase; Provisional; Region: PRK14986
1335916010446	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1335916010447	homodimer interface [polypeptide binding]; other site
1335916010448	active site pocket [active]
1335916010449	glycogen synthase; Provisional; Region: glgA; PRK00654
1335916010450	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1335916010451	ADP-binding pocket [chemical binding]; other site
1335916010452	homodimer interface [polypeptide binding]; other site
1335916010453	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
1335916010454	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1335916010455	ligand binding site; other site
1335916010456	oligomer interface; other site
1335916010457	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1335916010458	sulfate 1 binding site; other site
1335916010459	glycogen debranching enzyme; Provisional; Region: PRK03705
1335916010460	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1335916010461	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1335916010462	active site
1335916010463	catalytic site [active]
1335916010464	glycogen branching enzyme; Provisional; Region: PRK05402
1335916010465	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1335916010466	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1335916010467	active site
1335916010468	catalytic site [active]
1335916010469	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1335916010470	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1335916010471	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1335916010472	putative antibiotic transporter; Provisional; Region: PRK10739
1335916010473	low affinity gluconate transporter; Provisional; Region: PRK10472
1335916010474	gluconate transporter; Region: gntP; TIGR00791
1335916010475	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1335916010476	ATP-binding site [chemical binding]; other site
1335916010477	Gluconate-6-phosphate binding site [chemical binding]; other site
1335916010478	Shikimate kinase; Region: SKI; pfam01202
1335916010479	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1335916010480	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1335916010481	DNA binding site [nucleotide binding]
1335916010482	domain linker motif; other site
1335916010483	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1335916010484	putative ligand binding site [chemical binding]; other site
1335916010485	putative dimerization interface [polypeptide binding]; other site
1335916010486	Pirin-related protein [General function prediction only]; Region: COG1741
1335916010487	Pirin; Region: Pirin; pfam02678
1335916010488	putative oxidoreductase; Provisional; Region: PRK10206
1335916010489	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1335916010490	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1335916010491	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1335916010492	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1335916010493	Coenzyme A binding pocket [chemical binding]; other site
1335916010494	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1335916010495	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
1335916010496	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1335916010497	hypothetical protein; Provisional; Region: PRK10350
1335916010498	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
1335916010499	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
1335916010500	putative active site [active]
1335916010501	catalytic site [active]
1335916010502	putative metal binding site [ion binding]; other site
1335916010503	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1335916010504	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1335916010505	Walker A/P-loop; other site
1335916010506	ATP binding site [chemical binding]; other site
1335916010507	Q-loop/lid; other site
1335916010508	ABC transporter signature motif; other site
1335916010509	Walker B; other site
1335916010510	D-loop; other site
1335916010511	H-loop/switch region; other site
1335916010512	TOBE domain; Region: TOBE_2; pfam08402
1335916010513	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1335916010514	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916010515	dimer interface [polypeptide binding]; other site
1335916010516	conserved gate region; other site
1335916010517	putative PBP binding loops; other site
1335916010518	ABC-ATPase subunit interface; other site
1335916010519	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1335916010520	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916010521	dimer interface [polypeptide binding]; other site
1335916010522	conserved gate region; other site
1335916010523	putative PBP binding loops; other site
1335916010524	ABC-ATPase subunit interface; other site
1335916010525	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
1335916010526	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1335916010527	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
1335916010528	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1335916010529	Walker A/P-loop; other site
1335916010530	ATP binding site [chemical binding]; other site
1335916010531	Q-loop/lid; other site
1335916010532	ABC transporter signature motif; other site
1335916010533	Walker B; other site
1335916010534	D-loop; other site
1335916010535	H-loop/switch region; other site
1335916010536	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1335916010537	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1335916010538	Walker A/P-loop; other site
1335916010539	ATP binding site [chemical binding]; other site
1335916010540	Q-loop/lid; other site
1335916010541	ABC transporter signature motif; other site
1335916010542	Walker B; other site
1335916010543	D-loop; other site
1335916010544	H-loop/switch region; other site
1335916010545	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1335916010546	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1335916010547	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1335916010548	TM-ABC transporter signature motif; other site
1335916010549	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1335916010550	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1335916010551	TM-ABC transporter signature motif; other site
1335916010552	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1335916010553	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1335916010554	dimerization interface [polypeptide binding]; other site
1335916010555	ligand binding site [chemical binding]; other site
1335916010556	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
1335916010557	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1335916010558	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1335916010559	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1335916010560	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1335916010561	dimerization interface [polypeptide binding]; other site
1335916010562	ligand binding site [chemical binding]; other site
1335916010563	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1335916010564	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1335916010565	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1335916010566	DNA binding residues [nucleotide binding]
1335916010567	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1335916010568	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1335916010569	cell division protein FtsE; Provisional; Region: PRK10908
1335916010570	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916010571	Walker A/P-loop; other site
1335916010572	ATP binding site [chemical binding]; other site
1335916010573	Q-loop/lid; other site
1335916010574	ABC transporter signature motif; other site
1335916010575	Walker B; other site
1335916010576	D-loop; other site
1335916010577	H-loop/switch region; other site
1335916010578	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1335916010579	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1335916010580	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1335916010581	P loop; other site
1335916010582	GTP binding site [chemical binding]; other site
1335916010583	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1335916010584	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916010585	S-adenosylmethionine binding site [chemical binding]; other site
1335916010586	hypothetical protein; Provisional; Region: PRK10910
1335916010587	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1335916010588	Predicted membrane protein [Function unknown]; Region: COG3714
1335916010589	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
1335916010590	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1335916010591	metal-binding site [ion binding]
1335916010592	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1335916010593	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1335916010594	CPxP  motif; other site
1335916010595	hypothetical protein; Provisional; Region: PRK11212
1335916010596	hypothetical protein; Provisional; Region: PRK11615
1335916010597	major facilitator superfamily transporter; Provisional; Region: PRK05122
1335916010598	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916010599	putative substrate translocation pore; other site
1335916010600	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1335916010601	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1335916010602	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
1335916010603	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1335916010604	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1335916010605	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
1335916010606	substrate binding site [chemical binding]; other site
1335916010607	nickel transporter permease NikB; Provisional; Region: PRK10352
1335916010608	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916010609	dimer interface [polypeptide binding]; other site
1335916010610	conserved gate region; other site
1335916010611	putative PBP binding loops; other site
1335916010612	ABC-ATPase subunit interface; other site
1335916010613	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
1335916010614	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916010615	dimer interface [polypeptide binding]; other site
1335916010616	conserved gate region; other site
1335916010617	putative PBP binding loops; other site
1335916010618	ABC-ATPase subunit interface; other site
1335916010619	nickel responsive regulator; Provisional; Region: PRK02967
1335916010620	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
1335916010621	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
1335916010622	HicB family; Region: HicB; pfam05534
1335916010623	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1335916010624	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1335916010625	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1335916010626	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1335916010627	Walker A/P-loop; other site
1335916010628	ATP binding site [chemical binding]; other site
1335916010629	Q-loop/lid; other site
1335916010630	ABC transporter signature motif; other site
1335916010631	Walker B; other site
1335916010632	D-loop; other site
1335916010633	H-loop/switch region; other site
1335916010634	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1335916010635	Walker A/P-loop; other site
1335916010636	ATP binding site [chemical binding]; other site
1335916010637	Q-loop/lid; other site
1335916010638	ABC transporter signature motif; other site
1335916010639	Walker B; other site
1335916010640	D-loop; other site
1335916010641	H-loop/switch region; other site
1335916010642	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1335916010643	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1335916010644	HlyD family secretion protein; Region: HlyD; pfam00529
1335916010645	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1335916010646	HlyD family secretion protein; Region: HlyD_3; pfam13437
1335916010647	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
1335916010648	Protein of unknown function (DUF2776); Region: DUF2776; pfam10951
1335916010649	Predicted flavoproteins [General function prediction only]; Region: COG2081
1335916010650	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1335916010651	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1335916010652	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1335916010653	universal stress protein UspB; Provisional; Region: PRK04960
1335916010654	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1335916010655	Ligand Binding Site [chemical binding]; other site
1335916010656	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1335916010657	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916010658	putative substrate translocation pore; other site
1335916010659	POT family; Region: PTR2; pfam00854
1335916010660	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916010661	S-adenosylmethionine binding site [chemical binding]; other site
1335916010662	oligopeptidase A; Provisional; Region: PRK10911
1335916010663	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1335916010664	active site
1335916010665	Zn binding site [ion binding]; other site
1335916010666	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1335916010667	glutathione reductase; Validated; Region: PRK06116
1335916010668	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1335916010669	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916010670	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1335916010671	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1335916010672	dimerization interface [polypeptide binding]; other site
1335916010673	putative DNA binding site [nucleotide binding]; other site
1335916010674	putative Zn2+ binding site [ion binding]; other site
1335916010675	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1335916010676	ArsC family; Region: ArsC; pfam03960
1335916010677	catalytic residues [active]
1335916010678	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1335916010679	dimerization interface [polypeptide binding]; other site
1335916010680	putative DNA binding site [nucleotide binding]; other site
1335916010681	putative Zn2+ binding site [ion binding]; other site
1335916010682	Predicted permeases [General function prediction only]; Region: COG0701
1335916010683	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
1335916010684	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1335916010685	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916010686	DNA binding residues [nucleotide binding]
1335916010687	dimerization interface [polypeptide binding]; other site
1335916010688	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
1335916010689	MgtC family; Region: MgtC; pfam02308
1335916010690	acid-resistance protein; Provisional; Region: hdeB; PRK11566
1335916010691	acid-resistance protein; Provisional; Region: PRK10208
1335916010692	acid-resistance membrane protein; Provisional; Region: PRK10209
1335916010693	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
1335916010694	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1335916010695	pyruvate kinase; Provisional; Region: PRK05826
1335916010696	multidrug efflux system protein MdtE; Provisional; Region: PRK09859
1335916010697	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1335916010698	HlyD family secretion protein; Region: HlyD_3; pfam13437
1335916010699	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1335916010700	Protein export membrane protein; Region: SecD_SecF; cl14618
1335916010701	transcriptional regulator YdeO; Provisional; Region: PRK09940
1335916010702	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916010703	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
1335916010704	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916010705	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
1335916010706	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916010707	catalytic residue [active]
1335916010708	Haem-binding domain; Region: Haem_bd; pfam14376
1335916010709	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
1335916010710	trehalase; Provisional; Region: treF; PRK13270
1335916010711	Trehalase; Region: Trehalase; pfam01204
1335916010712	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1335916010713	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916010714	DNA binding residues [nucleotide binding]
1335916010715	dimerization interface [polypeptide binding]; other site
1335916010716	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1335916010717	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916010718	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1335916010719	putative effector binding pocket; other site
1335916010720	putative dimerization interface [polypeptide binding]; other site
1335916010721	inner membrane protein YhjD; Region: TIGR00766
1335916010722	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916010723	metabolite-proton symporter; Region: 2A0106; TIGR00883
1335916010724	putative substrate translocation pore; other site
1335916010725	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
1335916010726	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1335916010727	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1335916010728	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1335916010729	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1335916010730	substrate binding site [chemical binding]; other site
1335916010731	ATP binding site [chemical binding]; other site
1335916010732	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1335916010733	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1335916010734	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1335916010735	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1335916010736	putative diguanylate cyclase; Provisional; Region: PRK13561
1335916010737	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1335916010738	metal binding site [ion binding]; metal-binding site
1335916010739	active site
1335916010740	I-site; other site
1335916010741	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1335916010742	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
1335916010743	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1335916010744	binding surface
1335916010745	TPR motif; other site
1335916010746	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1335916010747	binding surface
1335916010748	TPR motif; other site
1335916010749	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1335916010750	endo-1,4-D-glucanase; Provisional; Region: PRK11097
1335916010751	cellulose synthase regulator protein; Provisional; Region: PRK11114
1335916010752	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
1335916010753	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1335916010754	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1335916010755	DXD motif; other site
1335916010756	PilZ domain; Region: PilZ; pfam07238
1335916010757	cell division protein; Provisional; Region: PRK10037
1335916010758	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
1335916010759	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
1335916010760	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
1335916010761	celllulose biosynthesis operon protein BcsF/YhjT; Region: cellullose_BcsF; TIGR03493
1335916010762	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
1335916010763	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1335916010764	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1335916010765	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1335916010766	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1335916010767	serine transporter; Region: stp; TIGR00814
1335916010768	dipeptide transporter; Provisional; Region: PRK10913
1335916010769	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1335916010770	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916010771	dimer interface [polypeptide binding]; other site
1335916010772	conserved gate region; other site
1335916010773	putative PBP binding loops; other site
1335916010774	ABC-ATPase subunit interface; other site
1335916010775	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1335916010776	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916010777	dimer interface [polypeptide binding]; other site
1335916010778	conserved gate region; other site
1335916010779	putative PBP binding loops; other site
1335916010780	ABC-ATPase subunit interface; other site
1335916010781	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1335916010782	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1335916010783	peptide binding site [polypeptide binding]; other site
1335916010784	phosphoethanolamine transferase; Provisional; Region: PRK11560
1335916010785	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1335916010786	Sulfatase; Region: Sulfatase; pfam00884
1335916010787	long polar fimbrial protein LpfE; Provisional; Region: PRK15205
1335916010788	long polar fimbrial protein LpfD; Provisional; Region: PRK15206
1335916010789	long polar fimbrial outer membrane usher protein LpfC; Provisional; Region: PRK15207
1335916010790	PapC N-terminal domain; Region: PapC_N; pfam13954
1335916010791	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1335916010792	PapC C-terminal domain; Region: PapC_C; pfam13953
1335916010793	long polar fimbrial chaperone LpfB; Provisional; Region: PRK15208
1335916010794	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1335916010795	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1335916010796	long polar fimbrial protein LpfA; Provisional; Region: PRK15209
1335916010797	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1335916010798	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916010799	putative substrate translocation pore; other site
1335916010800	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
1335916010801	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
1335916010802	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1335916010803	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1335916010804	Coenzyme A binding pocket [chemical binding]; other site
1335916010805	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1335916010806	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1335916010807	molybdopterin cofactor binding site [chemical binding]; other site
1335916010808	substrate binding site [chemical binding]; other site
1335916010809	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1335916010810	molybdopterin cofactor binding site; other site
1335916010811	putative outer membrane lipoprotein; Provisional; Region: PRK10510
1335916010812	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1335916010813	ligand binding site [chemical binding]; other site
1335916010814	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
1335916010815	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
1335916010816	dimerization interface [polypeptide binding]; other site
1335916010817	ligand binding site [chemical binding]; other site
1335916010818	NADP binding site [chemical binding]; other site
1335916010819	catalytic site [active]
1335916010820	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1335916010821	Predicted transcriptional regulator [Transcription]; Region: COG2944
1335916010822	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1335916010823	non-specific DNA binding site [nucleotide binding]; other site
1335916010824	salt bridge; other site
1335916010825	sequence-specific DNA binding site [nucleotide binding]; other site
1335916010826	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1335916010827	DNA-binding site [nucleotide binding]; DNA binding site
1335916010828	RNA-binding motif; other site
1335916010829	small toxic polypeptide; Provisional; Region: PRK09759
1335916010830	putative transposase OrfB; Reviewed; Region: PHA02517
1335916010831	HTH-like domain; Region: HTH_21; pfam13276
1335916010832	Integrase core domain; Region: rve; pfam00665
1335916010833	Integrase core domain; Region: rve_2; pfam13333
1335916010834	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1335916010835	Helix-turn-helix domain; Region: HTH_28; pfam13518
1335916010836	Helix-turn-helix domain; Region: HTH_28; pfam13518
1335916010837	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
1335916010838	DALR anticodon binding domain; Region: DALR_1; pfam05746
1335916010839	anticodon binding site; other site
1335916010840	tRNA binding surface [nucleotide binding]; other site
1335916010841	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1335916010842	dimer interface [polypeptide binding]; other site
1335916010843	motif 1; other site
1335916010844	active site
1335916010845	motif 2; other site
1335916010846	motif 3; other site
1335916010847	YsaB-like lipoprotein; Region: YsaB; pfam13983
1335916010848	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1335916010849	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1335916010850	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916010851	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1335916010852	hypothetical protein; Provisional; Region: PRK11383
1335916010853	yiaA/B two helix domain; Region: YiaAB; pfam05360
1335916010854	yiaA/B two helix domain; Region: YiaAB; pfam05360
1335916010855	hypothetical protein; Provisional; Region: PRK11403
1335916010856	yiaA/B two helix domain; Region: YiaAB; pfam05360
1335916010857	xylulokinase; Provisional; Region: PRK15027
1335916010858	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1335916010859	N- and C-terminal domain interface [polypeptide binding]; other site
1335916010860	active site
1335916010861	MgATP binding site [chemical binding]; other site
1335916010862	catalytic site [active]
1335916010863	metal binding site [ion binding]; metal-binding site
1335916010864	xylulose binding site [chemical binding]; other site
1335916010865	homodimer interface [polypeptide binding]; other site
1335916010866	xylose isomerase; Provisional; Region: PRK05474
1335916010867	xylose isomerase; Region: xylose_isom_A; TIGR02630
1335916010868	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
1335916010869	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
1335916010870	putative ligand binding site [chemical binding]; other site
1335916010871	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
1335916010872	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1335916010873	Walker A/P-loop; other site
1335916010874	ATP binding site [chemical binding]; other site
1335916010875	Q-loop/lid; other site
1335916010876	ABC transporter signature motif; other site
1335916010877	Walker B; other site
1335916010878	D-loop; other site
1335916010879	H-loop/switch region; other site
1335916010880	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1335916010881	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1335916010882	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1335916010883	TM-ABC transporter signature motif; other site
1335916010884	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
1335916010885	putative dimerization interface [polypeptide binding]; other site
1335916010886	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1335916010887	putative ligand binding site [chemical binding]; other site
1335916010888	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916010889	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1335916010890	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916010891	hypothetical protein; Provisional; Region: PRK10356
1335916010892	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
1335916010893	alpha-amylase; Reviewed; Region: malS; PRK09505
1335916010894	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1335916010895	active site
1335916010896	catalytic site [active]
1335916010897	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
1335916010898	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1335916010899	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916010900	homodimer interface [polypeptide binding]; other site
1335916010901	catalytic residue [active]
1335916010902	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1335916010903	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1335916010904	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1335916010905	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1335916010906	Bacterial transcriptional regulator; Region: IclR; pfam01614
1335916010907	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
1335916010908	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
1335916010909	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
1335916010910	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
1335916010911	DctM-like transporters; Region: DctM; pfam06808
1335916010912	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1335916010913	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
1335916010914	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1335916010915	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1335916010916	putative N- and C-terminal domain interface [polypeptide binding]; other site
1335916010917	putative active site [active]
1335916010918	MgATP binding site [chemical binding]; other site
1335916010919	catalytic site [active]
1335916010920	metal binding site [ion binding]; metal-binding site
1335916010921	putative xylulose binding site [chemical binding]; other site
1335916010922	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1335916010923	active site
1335916010924	dimer interface [polypeptide binding]; other site
1335916010925	magnesium binding site [ion binding]; other site
1335916010926	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
1335916010927	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1335916010928	AP (apurinic/apyrimidinic) site pocket; other site
1335916010929	DNA interaction; other site
1335916010930	Metal-binding active site; metal-binding site
1335916010931	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1335916010932	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1335916010933	intersubunit interface [polypeptide binding]; other site
1335916010934	active site
1335916010935	Zn2+ binding site [ion binding]; other site
1335916010936	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1335916010937	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1335916010938	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916010939	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1335916010940	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1335916010941	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1335916010942	HlyD family secretion protein; Region: HlyD_3; pfam13437
1335916010943	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
1335916010944	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
1335916010945	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1335916010946	NAD(P) binding site [chemical binding]; other site
1335916010947	catalytic residues [active]
1335916010948	putative alcohol dehydrogenase; Provisional; Region: PRK09860
1335916010949	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1335916010950	dimer interface [polypeptide binding]; other site
1335916010951	active site
1335916010952	metal binding site [ion binding]; metal-binding site
1335916010953	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
1335916010954	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1335916010955	G1 box; other site
1335916010956	putative GEF interaction site [polypeptide binding]; other site
1335916010957	GTP/Mg2+ binding site [chemical binding]; other site
1335916010958	Switch I region; other site
1335916010959	G2 box; other site
1335916010960	G3 box; other site
1335916010961	Switch II region; other site
1335916010962	G4 box; other site
1335916010963	G5 box; other site
1335916010964	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1335916010965	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
1335916010966	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
1335916010967	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1335916010968	selenocysteine synthase; Provisional; Region: PRK04311
1335916010969	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
1335916010970	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1335916010971	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1335916010972	catalytic residue [active]
1335916010973	putative glutathione S-transferase; Provisional; Region: PRK10357
1335916010974	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
1335916010975	putative C-terminal domain interface [polypeptide binding]; other site
1335916010976	putative GSH binding site (G-site) [chemical binding]; other site
1335916010977	putative dimer interface [polypeptide binding]; other site
1335916010978	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
1335916010979	dimer interface [polypeptide binding]; other site
1335916010980	N-terminal domain interface [polypeptide binding]; other site
1335916010981	putative substrate binding pocket (H-site) [chemical binding]; other site
1335916010982	PAAR motif; Region: PAAR_motif; cl15808
1335916010983	RHS Repeat; Region: RHS_repeat; pfam05593
1335916010984	RHS Repeat; Region: RHS_repeat; pfam05593
1335916010985	RHS Repeat; Region: RHS_repeat; cl11982
1335916010986	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1335916010987	RHS Repeat; Region: RHS_repeat; pfam05593
1335916010988	RHS Repeat; Region: RHS_repeat; pfam05593
1335916010989	RHS protein; Region: RHS; pfam03527
1335916010990	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1335916010991	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
1335916010992	putative lyase; Provisional; Region: PRK09687
1335916010993	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1335916010994	RHS protein; Region: RHS; pfam03527
1335916010995	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1335916010996	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1335916010997	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1335916010998	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1335916010999	HlyD family secretion protein; Region: HlyD_3; pfam13437
1335916011000	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
1335916011001	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1335916011002	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1335916011003	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1335916011004	active site
1335916011005	P-loop; other site
1335916011006	phosphorylation site [posttranslational modification]
1335916011007	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1335916011008	active site
1335916011009	phosphorylation site [posttranslational modification]
1335916011010	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1335916011011	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1335916011012	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1335916011013	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1335916011014	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
1335916011015	hypothetical protein; Provisional; Region: PRK11020
1335916011016	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
1335916011017	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916011018	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1335916011019	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1335916011020	trimer interface [polypeptide binding]; other site
1335916011021	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1335916011022	trimer interface [polypeptide binding]; other site
1335916011023	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
1335916011024	Haemagglutinin; Region: HIM; pfam05662
1335916011025	Haemagglutinin; Region: HIM; pfam05662
1335916011026	YadA-like C-terminal region; Region: YadA; pfam03895
1335916011027	L-lactate permease; Provisional; Region: PRK10420
1335916011028	glycolate transporter; Provisional; Region: PRK09695
1335916011029	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
1335916011030	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916011031	DNA-binding site [nucleotide binding]; DNA binding site
1335916011032	FCD domain; Region: FCD; pfam07729
1335916011033	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
1335916011034	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1335916011035	phosphate binding site [ion binding]; other site
1335916011036	putative rRNA methylase; Provisional; Region: PRK10358
1335916011037	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1335916011038	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1335916011039	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1335916011040	trimer interface [polypeptide binding]; other site
1335916011041	active site
1335916011042	substrate binding site [chemical binding]; other site
1335916011043	CoA binding site [chemical binding]; other site
1335916011044	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1335916011045	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1335916011046	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1335916011047	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1335916011048	SecA binding site; other site
1335916011049	Preprotein binding site; other site
1335916011050	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1335916011051	GSH binding site [chemical binding]; other site
1335916011052	catalytic residues [active]
1335916011053	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1335916011054	active site residue [active]
1335916011055	phosphoglyceromutase; Provisional; Region: PRK05434
1335916011056	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
1335916011057	AmiB activator; Provisional; Region: PRK11637
1335916011058	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1335916011059	Peptidase family M23; Region: Peptidase_M23; pfam01551
1335916011060	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1335916011061	NodB motif; other site
1335916011062	putative active site [active]
1335916011063	putative catalytic site [active]
1335916011064	Zn binding site [ion binding]; other site
1335916011065	putative glycosyl transferase; Provisional; Region: PRK10073
1335916011066	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916011067	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1335916011068	active site
1335916011069	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1335916011070	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1335916011071	NAD(P) binding site [chemical binding]; other site
1335916011072	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1335916011073	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1335916011074	substrate-cofactor binding pocket; other site
1335916011075	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916011076	catalytic residue [active]
1335916011077	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1335916011078	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1335916011079	NADP binding site [chemical binding]; other site
1335916011080	homopentamer interface [polypeptide binding]; other site
1335916011081	substrate binding site [chemical binding]; other site
1335916011082	active site
1335916011083	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1335916011084	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1335916011085	putative active site [active]
1335916011086	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1335916011087	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1335916011088	putative active site [active]
1335916011089	O-Antigen ligase; Region: Wzy_C; pfam04932
1335916011090	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1335916011091	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1335916011092	active site
1335916011093	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1335916011094	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1335916011095	Ligand binding site; other site
1335916011096	metal-binding site
1335916011097	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1335916011098	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
1335916011099	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1335916011100	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1335916011101	Ligand binding site; other site
1335916011102	metal-binding site
1335916011103	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1335916011104	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1335916011105	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1335916011106	Ligand binding site; other site
1335916011107	metal-binding site
1335916011108	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1335916011109	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
1335916011110	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1335916011111	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1335916011112	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
1335916011113	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1335916011114	putative active site [active]
1335916011115	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1335916011116	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1335916011117	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1335916011118	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1335916011119	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1335916011120	active site
1335916011121	(T/H)XGH motif; other site
1335916011122	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1335916011123	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1335916011124	DNA binding site [nucleotide binding]
1335916011125	catalytic residue [active]
1335916011126	H2TH interface [polypeptide binding]; other site
1335916011127	putative catalytic residues [active]
1335916011128	turnover-facilitating residue; other site
1335916011129	intercalation triad [nucleotide binding]; other site
1335916011130	8OG recognition residue [nucleotide binding]; other site
1335916011131	putative reading head residues; other site
1335916011132	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1335916011133	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1335916011134	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1335916011135	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1335916011136	hypothetical protein; Reviewed; Region: PRK00024
1335916011137	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1335916011138	MPN+ (JAMM) motif; other site
1335916011139	Zinc-binding site [ion binding]; other site
1335916011140	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1335916011141	Flavoprotein; Region: Flavoprotein; pfam02441
1335916011142	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1335916011143	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1335916011144	trimer interface [polypeptide binding]; other site
1335916011145	active site
1335916011146	division inhibitor protein; Provisional; Region: slmA; PRK09480
1335916011147	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1335916011148	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1335916011149	active site
1335916011150	ribonuclease PH; Reviewed; Region: rph; PRK00173
1335916011151	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1335916011152	hexamer interface [polypeptide binding]; other site
1335916011153	active site
1335916011154	hypothetical protein; Provisional; Region: PRK11820
1335916011155	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1335916011156	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1335916011157	DNA-damage-inducible protein D; Provisional; Region: dinD; PRK11525
1335916011158	BRO family, N-terminal domain; Region: Bro-N; pfam02498
1335916011159	Predicted membrane protein [Function unknown]; Region: COG2860
1335916011160	UPF0126 domain; Region: UPF0126; pfam03458
1335916011161	UPF0126 domain; Region: UPF0126; pfam03458
1335916011162	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
1335916011163	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
1335916011164	nucleotide binding pocket [chemical binding]; other site
1335916011165	K-X-D-G motif; other site
1335916011166	catalytic site [active]
1335916011167	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1335916011168	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1335916011169	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1335916011170	catalytic site [active]
1335916011171	G-X2-G-X-G-K; other site
1335916011172	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1335916011173	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1335916011174	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1335916011175	Zn2+ binding site [ion binding]; other site
1335916011176	Mg2+ binding site [ion binding]; other site
1335916011177	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1335916011178	synthetase active site [active]
1335916011179	NTP binding site [chemical binding]; other site
1335916011180	metal binding site [ion binding]; metal-binding site
1335916011181	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1335916011182	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1335916011183	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
1335916011184	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1335916011185	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
1335916011186	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1335916011187	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1335916011188	generic binding surface II; other site
1335916011189	ssDNA binding site; other site
1335916011190	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1335916011191	ATP binding site [chemical binding]; other site
1335916011192	putative Mg++ binding site [ion binding]; other site
1335916011193	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1335916011194	nucleotide binding region [chemical binding]; other site
1335916011195	ATP-binding site [chemical binding]; other site
1335916011196	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1335916011197	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1335916011198	AsmA family; Region: AsmA; pfam05170
1335916011199	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
1335916011200	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1335916011201	putative alpha-glucosidase; Provisional; Region: PRK10658
1335916011202	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1335916011203	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
1335916011204	active site
1335916011205	homotrimer interface [polypeptide binding]; other site
1335916011206	catalytic site [active]
1335916011207	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
1335916011208	putative transporter; Provisional; Region: PRK11462
1335916011209	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1335916011210	integrase; Provisional; Region: PRK09692
1335916011211	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1335916011212	active site
1335916011213	Int/Topo IB signature motif; other site
1335916011214	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1335916011215	Part of AAA domain; Region: AAA_19; pfam13245
1335916011216	Family description; Region: UvrD_C_2; pfam13538
1335916011217	AAA ATPase domain; Region: AAA_15; pfam13175
1335916011218	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916011219	Walker A/P-loop; other site
1335916011220	ATP binding site [chemical binding]; other site
1335916011221	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1335916011222	putative active site [active]
1335916011223	putative metal-binding site [ion binding]; other site
1335916011224	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1335916011225	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916011226	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
1335916011227	putative transposase OrfB; Reviewed; Region: PHA02517
1335916011228	HTH-like domain; Region: HTH_21; pfam13276
1335916011229	Integrase core domain; Region: rve; pfam00665
1335916011230	Integrase core domain; Region: rve_2; pfam13333
1335916011231	Transposase; Region: HTH_Tnp_1; cl17663
1335916011232	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1335916011233	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1335916011234	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1335916011235	MPN+ (JAMM) motif; other site
1335916011236	Zinc-binding site [ion binding]; other site
1335916011237	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1335916011238	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1335916011239	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1335916011240	sugar efflux transporter; Region: 2A0120; TIGR00899
1335916011241	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916011242	putative substrate translocation pore; other site
1335916011243	EamA-like transporter family; Region: EamA; pfam00892
1335916011244	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1335916011245	EamA-like transporter family; Region: EamA; pfam00892
1335916011246	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
1335916011247	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916011248	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
1335916011249	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
1335916011250	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916011251	putative substrate translocation pore; other site
1335916011252	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
1335916011253	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1335916011254	cryptic adenine deaminase; Provisional; Region: PRK10027
1335916011255	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1335916011256	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
1335916011257	active site
1335916011258	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1335916011259	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
1335916011260	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916011261	putative substrate translocation pore; other site
1335916011262	regulatory protein UhpC; Provisional; Region: PRK11663
1335916011263	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916011264	putative substrate translocation pore; other site
1335916011265	sensory histidine kinase UhpB; Provisional; Region: PRK11644
1335916011266	MASE1; Region: MASE1; pfam05231
1335916011267	Histidine kinase; Region: HisKA_3; pfam07730
1335916011268	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
1335916011269	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916011270	active site
1335916011271	phosphorylation site [posttranslational modification]
1335916011272	intermolecular recognition site; other site
1335916011273	dimerization interface [polypeptide binding]; other site
1335916011274	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916011275	DNA binding residues [nucleotide binding]
1335916011276	dimerization interface [polypeptide binding]; other site
1335916011277	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
1335916011278	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1335916011279	putative valine binding site [chemical binding]; other site
1335916011280	dimer interface [polypeptide binding]; other site
1335916011281	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
1335916011282	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1335916011283	PYR/PP interface [polypeptide binding]; other site
1335916011284	dimer interface [polypeptide binding]; other site
1335916011285	TPP binding site [chemical binding]; other site
1335916011286	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1335916011287	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1335916011288	TPP-binding site [chemical binding]; other site
1335916011289	dimer interface [polypeptide binding]; other site
1335916011290	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
1335916011291	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916011292	putative substrate translocation pore; other site
1335916011293	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1335916011294	Domain of unknown function (DUF202); Region: DUF202; pfam02656
1335916011295	Predicted membrane protein [Function unknown]; Region: COG2149
1335916011296	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1335916011297	Sulfatase; Region: Sulfatase; pfam00884
1335916011298	putative transporter; Provisional; Region: PRK10484
1335916011299	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
1335916011300	Na binding site [ion binding]; other site
1335916011301	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1335916011302	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916011303	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1335916011304	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
1335916011305	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1335916011306	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1335916011307	active site turn [active]
1335916011308	phosphorylation site [posttranslational modification]
1335916011309	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1335916011310	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916011311	DNA-binding site [nucleotide binding]; DNA binding site
1335916011312	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1335916011313	putative transporter; Validated; Region: PRK03818
1335916011314	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1335916011315	TrkA-C domain; Region: TrkA_C; pfam02080
1335916011316	TrkA-C domain; Region: TrkA_C; pfam02080
1335916011317	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1335916011318	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1335916011319	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1335916011320	putative dimer interface [polypeptide binding]; other site
1335916011321	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1335916011322	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1335916011323	putative dimer interface [polypeptide binding]; other site
1335916011324	hypothetical protein; Provisional; Region: PRK11616
1335916011325	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
1335916011326	putative oxidoreductase; Provisional; Region: PRK11445
1335916011327	hypothetical protein; Provisional; Region: PRK07236
1335916011328	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916011329	D-galactonate transporter; Region: 2A0114; TIGR00893
1335916011330	putative substrate translocation pore; other site
1335916011331	galactonate dehydratase; Provisional; Region: PRK14017
1335916011332	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
1335916011333	putative active site pocket [active]
1335916011334	putative metal binding site [ion binding]; other site
1335916011335	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
1335916011336	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1335916011337	active site
1335916011338	intersubunit interface [polypeptide binding]; other site
1335916011339	catalytic residue [active]
1335916011340	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
1335916011341	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
1335916011342	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1335916011343	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916011344	DNA-binding site [nucleotide binding]; DNA binding site
1335916011345	FCD domain; Region: FCD; pfam07729
1335916011346	hypothetical protein; Provisional; Region: PRK10215
1335916011347	sugar phosphate phosphatase; Provisional; Region: PRK10513
1335916011348	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916011349	active site
1335916011350	motif I; other site
1335916011351	motif II; other site
1335916011352	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916011353	hypothetical protein; Provisional; Region: PRK11426
1335916011354	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1335916011355	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1335916011356	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916011357	Mg2+ binding site [ion binding]; other site
1335916011358	G-X-G motif; other site
1335916011359	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1335916011360	anchoring element; other site
1335916011361	dimer interface [polypeptide binding]; other site
1335916011362	ATP binding site [chemical binding]; other site
1335916011363	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1335916011364	active site
1335916011365	putative metal-binding site [ion binding]; other site
1335916011366	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1335916011367	recF protein; Region: recf; TIGR00611
1335916011368	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916011369	Walker A/P-loop; other site
1335916011370	ATP binding site [chemical binding]; other site
1335916011371	Q-loop/lid; other site
1335916011372	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916011373	ABC transporter signature motif; other site
1335916011374	Walker B; other site
1335916011375	D-loop; other site
1335916011376	H-loop/switch region; other site
1335916011377	DNA polymerase III subunit beta; Validated; Region: PRK05643
1335916011378	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1335916011379	putative DNA binding surface [nucleotide binding]; other site
1335916011380	dimer interface [polypeptide binding]; other site
1335916011381	beta-clamp/clamp loader binding surface; other site
1335916011382	beta-clamp/translesion DNA polymerase binding surface; other site
1335916011383	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1335916011384	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1335916011385	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916011386	Walker A motif; other site
1335916011387	ATP binding site [chemical binding]; other site
1335916011388	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1335916011389	Walker B motif; other site
1335916011390	arginine finger; other site
1335916011391	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1335916011392	DnaA box-binding interface [nucleotide binding]; other site
1335916011393	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1335916011394	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1335916011395	membrane protein insertase; Provisional; Region: PRK01318
1335916011396	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1335916011397	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1335916011398	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1335916011399	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1335916011400	G1 box; other site
1335916011401	GTP/Mg2+ binding site [chemical binding]; other site
1335916011402	Switch I region; other site
1335916011403	G2 box; other site
1335916011404	Switch II region; other site
1335916011405	G3 box; other site
1335916011406	G4 box; other site
1335916011407	G5 box; other site
1335916011408	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1335916011409	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
1335916011410	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1335916011411	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1335916011412	catalytic residue [active]
1335916011413	tryptophan permease TnaB; Provisional; Region: PRK09664
1335916011414	aromatic amino acid transport protein; Region: araaP; TIGR00837
1335916011415	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
1335916011416	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916011417	putative substrate translocation pore; other site
1335916011418	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
1335916011419	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916011420	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1335916011421	substrate binding pocket [chemical binding]; other site
1335916011422	dimerization interface [polypeptide binding]; other site
1335916011423	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1335916011424	Predicted flavoprotein [General function prediction only]; Region: COG0431
1335916011425	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1335916011426	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1335916011427	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
1335916011428	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916011429	active site
1335916011430	motif I; other site
1335916011431	motif II; other site
1335916011432	putative inner membrane protein; Provisional; Region: PRK09823
1335916011433	Uncharacterized protein family (UPF0167); Region: UPF0167; cl01252
1335916011434	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1335916011435	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1335916011436	active site
1335916011437	trimer interface [polypeptide binding]; other site
1335916011438	allosteric site; other site
1335916011439	active site lid [active]
1335916011440	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
1335916011441	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
1335916011442	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1335916011443	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1335916011444	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1335916011445	trimer interface; other site
1335916011446	sugar binding site [chemical binding]; other site
1335916011447	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1335916011448	beta-galactosidase; Region: BGL; TIGR03356
1335916011449	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
1335916011450	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1335916011451	active site turn [active]
1335916011452	phosphorylation site [posttranslational modification]
1335916011453	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1335916011454	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1335916011455	HPr interaction site; other site
1335916011456	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1335916011457	active site
1335916011458	phosphorylation site [posttranslational modification]
1335916011459	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1335916011460	CAT RNA binding domain; Region: CAT_RBD; pfam03123
1335916011461	PRD domain; Region: PRD; pfam00874
1335916011462	PRD domain; Region: PRD; pfam00874
1335916011463	transcriptional regulator PhoU; Provisional; Region: PRK11115
1335916011464	PhoU domain; Region: PhoU; pfam01895
1335916011465	PhoU domain; Region: PhoU; pfam01895
1335916011466	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
1335916011467	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1335916011468	Walker A/P-loop; other site
1335916011469	ATP binding site [chemical binding]; other site
1335916011470	Q-loop/lid; other site
1335916011471	ABC transporter signature motif; other site
1335916011472	Walker B; other site
1335916011473	D-loop; other site
1335916011474	H-loop/switch region; other site
1335916011475	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1335916011476	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916011477	dimer interface [polypeptide binding]; other site
1335916011478	conserved gate region; other site
1335916011479	putative PBP binding loops; other site
1335916011480	ABC-ATPase subunit interface; other site
1335916011481	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
1335916011482	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916011483	dimer interface [polypeptide binding]; other site
1335916011484	conserved gate region; other site
1335916011485	putative PBP binding loops; other site
1335916011486	ABC-ATPase subunit interface; other site
1335916011487	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916011488	Fimbrial protein; Region: Fimbrial; cl01416
1335916011489	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1335916011490	PapC N-terminal domain; Region: PapC_N; pfam13954
1335916011491	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1335916011492	PapC C-terminal domain; Region: PapC_C; pfam13953
1335916011493	fimbrial protein; Provisional; Region: lpfA; PRK15289
1335916011494	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1335916011495	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1335916011496	glutaminase active site [active]
1335916011497	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1335916011498	dimer interface [polypeptide binding]; other site
1335916011499	active site
1335916011500	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1335916011501	dimer interface [polypeptide binding]; other site
1335916011502	active site
1335916011503	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1335916011504	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1335916011505	Substrate binding site; other site
1335916011506	Mg++ binding site; other site
1335916011507	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1335916011508	active site
1335916011509	substrate binding site [chemical binding]; other site
1335916011510	CoA binding site [chemical binding]; other site
1335916011511	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1335916011512	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1335916011513	gamma subunit interface [polypeptide binding]; other site
1335916011514	epsilon subunit interface [polypeptide binding]; other site
1335916011515	LBP interface [polypeptide binding]; other site
1335916011516	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1335916011517	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1335916011518	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1335916011519	alpha subunit interaction interface [polypeptide binding]; other site
1335916011520	Walker A motif; other site
1335916011521	ATP binding site [chemical binding]; other site
1335916011522	Walker B motif; other site
1335916011523	inhibitor binding site; inhibition site
1335916011524	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1335916011525	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1335916011526	core domain interface [polypeptide binding]; other site
1335916011527	delta subunit interface [polypeptide binding]; other site
1335916011528	epsilon subunit interface [polypeptide binding]; other site
1335916011529	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1335916011530	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1335916011531	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1335916011532	beta subunit interaction interface [polypeptide binding]; other site
1335916011533	Walker A motif; other site
1335916011534	ATP binding site [chemical binding]; other site
1335916011535	Walker B motif; other site
1335916011536	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1335916011537	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1335916011538	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1335916011539	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1335916011540	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1335916011541	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1335916011542	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1335916011543	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1335916011544	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
1335916011545	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1335916011546	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916011547	S-adenosylmethionine binding site [chemical binding]; other site
1335916011548	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1335916011549	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1335916011550	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1335916011551	FMN-binding protein MioC; Provisional; Region: PRK09004
1335916011552	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1335916011553	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1335916011554	putative DNA binding site [nucleotide binding]; other site
1335916011555	putative Zn2+ binding site [ion binding]; other site
1335916011556	AsnC family; Region: AsnC_trans_reg; pfam01037
1335916011557	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
1335916011558	dimer interface [polypeptide binding]; other site
1335916011559	active site
1335916011560	hypothetical protein; Provisional; Region: yieM; PRK10997
1335916011561	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1335916011562	metal ion-dependent adhesion site (MIDAS); other site
1335916011563	regulatory ATPase RavA; Provisional; Region: PRK13531
1335916011564	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916011565	Walker A motif; other site
1335916011566	ATP binding site [chemical binding]; other site
1335916011567	Walker B motif; other site
1335916011568	arginine finger; other site
1335916011569	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
1335916011570	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
1335916011571	potassium uptake protein; Region: kup; TIGR00794
1335916011572	D-ribose pyranase; Provisional; Region: PRK11797
1335916011573	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
1335916011574	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1335916011575	Walker A/P-loop; other site
1335916011576	ATP binding site [chemical binding]; other site
1335916011577	Q-loop/lid; other site
1335916011578	ABC transporter signature motif; other site
1335916011579	Walker B; other site
1335916011580	D-loop; other site
1335916011581	H-loop/switch region; other site
1335916011582	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1335916011583	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
1335916011584	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1335916011585	putative transporter; Provisional; Region: PRK10504
1335916011586	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916011587	putative substrate translocation pore; other site
1335916011588	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916011589	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1335916011590	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916011591	DNA-binding site [nucleotide binding]; DNA binding site
1335916011592	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1335916011593	transcriptional regulator HdfR; Provisional; Region: PRK03601
1335916011594	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916011595	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1335916011596	dimerization interface [polypeptide binding]; other site
1335916011597	hypothetical protein; Provisional; Region: PRK11027
1335916011598	putative ATP-dependent protease; Provisional; Region: PRK09862
1335916011599	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1335916011600	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916011601	Walker A motif; other site
1335916011602	ATP binding site [chemical binding]; other site
1335916011603	Walker B motif; other site
1335916011604	arginine finger; other site
1335916011605	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1335916011606	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
1335916011607	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1335916011608	PYR/PP interface [polypeptide binding]; other site
1335916011609	dimer interface [polypeptide binding]; other site
1335916011610	TPP binding site [chemical binding]; other site
1335916011611	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1335916011612	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1335916011613	TPP-binding site [chemical binding]; other site
1335916011614	dimer interface [polypeptide binding]; other site
1335916011615	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1335916011616	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1335916011617	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1335916011618	homodimer interface [polypeptide binding]; other site
1335916011619	substrate-cofactor binding pocket; other site
1335916011620	catalytic residue [active]
1335916011621	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1335916011622	threonine dehydratase; Reviewed; Region: PRK09224
1335916011623	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1335916011624	tetramer interface [polypeptide binding]; other site
1335916011625	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916011626	catalytic residue [active]
1335916011627	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1335916011628	putative Ile/Val binding site [chemical binding]; other site
1335916011629	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1335916011630	putative Ile/Val binding site [chemical binding]; other site
1335916011631	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916011632	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
1335916011633	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
1335916011634	putative dimerization interface [polypeptide binding]; other site
1335916011635	ketol-acid reductoisomerase; Validated; Region: PRK05225
1335916011636	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1335916011637	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1335916011638	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1335916011639	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
1335916011640	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1335916011641	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3692
1335916011642	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
1335916011643	Part of AAA domain; Region: AAA_19; pfam13245
1335916011644	Family description; Region: UvrD_C_2; pfam13538
1335916011645	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
1335916011646	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1335916011647	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1335916011648	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1335916011649	ATP binding site [chemical binding]; other site
1335916011650	Mg++ binding site [ion binding]; other site
1335916011651	motif III; other site
1335916011652	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1335916011653	nucleotide binding region [chemical binding]; other site
1335916011654	ATP-binding site [chemical binding]; other site
1335916011655	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1335916011656	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1335916011657	catalytic residues [active]
1335916011658	putative rho operon leader peptide; Provisional; Region: PRK09979
1335916011659	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1335916011660	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1335916011661	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1335916011662	RNA binding site [nucleotide binding]; other site
1335916011663	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1335916011664	multimer interface [polypeptide binding]; other site
1335916011665	Walker A motif; other site
1335916011666	ATP binding site [chemical binding]; other site
1335916011667	Walker B motif; other site
1335916011668	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
1335916011669	Chain length determinant protein; Region: Wzz; pfam02706
1335916011670	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
1335916011671	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1335916011672	active site
1335916011673	homodimer interface [polypeptide binding]; other site
1335916011674	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1335916011675	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1335916011676	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1335916011677	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1335916011678	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
1335916011679	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1335916011680	NAD binding site [chemical binding]; other site
1335916011681	substrate binding site [chemical binding]; other site
1335916011682	homodimer interface [polypeptide binding]; other site
1335916011683	active site
1335916011684	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1335916011685	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1335916011686	substrate binding site; other site
1335916011687	tetramer interface; other site
1335916011688	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
1335916011689	Coenzyme A binding pocket [chemical binding]; other site
1335916011690	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1335916011691	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1335916011692	inhibitor-cofactor binding pocket; inhibition site
1335916011693	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916011694	catalytic residue [active]
1335916011695	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1335916011696	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1335916011697	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
1335916011698	putative common antigen polymerase; Provisional; Region: PRK02975
1335916011699	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1335916011700	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1335916011701	putative transport protein YifK; Provisional; Region: PRK10746
1335916011702	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1335916011703	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916011704	FeS/SAM binding site; other site
1335916011705	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1335916011706	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
1335916011707	HemY protein N-terminus; Region: HemY_N; pfam07219
1335916011708	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
1335916011709	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1335916011710	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1335916011711	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1335916011712	active site
1335916011713	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1335916011714	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1335916011715	domain interfaces; other site
1335916011716	active site
1335916011717	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
1335916011718	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1335916011719	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1335916011720	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
1335916011721	putative iron binding site [ion binding]; other site
1335916011722	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
1335916011723	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1335916011724	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1335916011725	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1335916011726	hypothetical protein; Provisional; Region: PRK10963
1335916011727	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
1335916011728	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1335916011729	active site
1335916011730	DNA binding site [nucleotide binding]
1335916011731	Int/Topo IB signature motif; other site
1335916011732	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
1335916011733	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916011734	motif II; other site
1335916011735	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1335916011736	Part of AAA domain; Region: AAA_19; pfam13245
1335916011737	Family description; Region: UvrD_C_2; pfam13538
1335916011738	Predicted periplasmic protein [Function unknown]; Region: COG3698
1335916011739	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
1335916011740	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1335916011741	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1335916011742	Cl binding site [ion binding]; other site
1335916011743	oligomer interface [polypeptide binding]; other site
1335916011744	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
1335916011745	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916011746	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1335916011747	magnesium/nickel/cobalt transporter CorA; Provisional; Region: PRK11085
1335916011748	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
1335916011749	EamA-like transporter family; Region: EamA; cl17759
1335916011750	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1335916011751	CoenzymeA binding site [chemical binding]; other site
1335916011752	subunit interaction site [polypeptide binding]; other site
1335916011753	PHB binding site; other site
1335916011754	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1335916011755	dimerization interface [polypeptide binding]; other site
1335916011756	substrate binding site [chemical binding]; other site
1335916011757	active site
1335916011758	calcium binding site [ion binding]; other site
1335916011759	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1335916011760	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1335916011761	ATP binding site [chemical binding]; other site
1335916011762	putative Mg++ binding site [ion binding]; other site
1335916011763	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1335916011764	nucleotide binding region [chemical binding]; other site
1335916011765	ATP-binding site [chemical binding]; other site
1335916011766	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1335916011767	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1335916011768	threonine efflux system; Provisional; Region: PRK10229
1335916011769	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
1335916011770	lysophospholipase L2; Provisional; Region: PRK10749
1335916011771	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1335916011772	putative hydrolase; Provisional; Region: PRK10976
1335916011773	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916011774	active site
1335916011775	motif I; other site
1335916011776	motif II; other site
1335916011777	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916011778	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1335916011779	EamA-like transporter family; Region: EamA; pfam00892
1335916011780	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1335916011781	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916011782	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1335916011783	putative dimerization interface [polypeptide binding]; other site
1335916011784	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1335916011785	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1335916011786	THF binding site; other site
1335916011787	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1335916011788	substrate binding site [chemical binding]; other site
1335916011789	THF binding site; other site
1335916011790	zinc-binding site [ion binding]; other site
1335916011791	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1335916011792	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
1335916011793	uridine phosphorylase; Provisional; Region: PRK11178
1335916011794	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
1335916011795	DNA recombination protein RmuC; Provisional; Region: PRK10361
1335916011796	RmuC family; Region: RmuC; pfam02646
1335916011797	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1335916011798	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916011799	S-adenosylmethionine binding site [chemical binding]; other site
1335916011800	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1335916011801	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1335916011802	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1335916011803	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1335916011804	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
1335916011805	twin arginine translocase protein A; Provisional; Region: tatA; PRK00575
1335916011806	sec-independent translocase; Provisional; Region: PRK01770
1335916011807	sec-independent translocase; Provisional; Region: tatB; PRK00404
1335916011808	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
1335916011809	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1335916011810	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
1335916011811	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
1335916011812	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
1335916011813	FMN reductase; Validated; Region: fre; PRK08051
1335916011814	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1335916011815	FAD binding pocket [chemical binding]; other site
1335916011816	FAD binding motif [chemical binding]; other site
1335916011817	phosphate binding motif [ion binding]; other site
1335916011818	beta-alpha-beta structure motif; other site
1335916011819	NAD binding pocket [chemical binding]; other site
1335916011820	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
1335916011821	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1335916011822	dimer interface [polypeptide binding]; other site
1335916011823	active site
1335916011824	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
1335916011825	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1335916011826	substrate binding site [chemical binding]; other site
1335916011827	oxyanion hole (OAH) forming residues; other site
1335916011828	trimer interface [polypeptide binding]; other site
1335916011829	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1335916011830	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1335916011831	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1335916011832	proline dipeptidase; Provisional; Region: PRK13607
1335916011833	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1335916011834	active site
1335916011835	hypothetical protein; Provisional; Region: PRK11568
1335916011836	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1335916011837	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1335916011838	potassium transporter; Provisional; Region: PRK10750
1335916011839	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1335916011840	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
1335916011841	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1335916011842	Walker A motif; other site
1335916011843	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1335916011844	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1335916011845	GTP binding site; other site
1335916011846	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
1335916011847	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1335916011848	serine/threonine protein kinase; Provisional; Region: PRK11768
1335916011849	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1335916011850	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1335916011851	catalytic residues [active]
1335916011852	hinge region; other site
1335916011853	alpha helical domain; other site
1335916011854	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1335916011855	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916011856	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1335916011857	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1335916011858	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
1335916011859	putative acyl-acceptor binding pocket; other site
1335916011860	DNA polymerase I; Provisional; Region: PRK05755
1335916011861	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1335916011862	active site
1335916011863	metal binding site 1 [ion binding]; metal-binding site
1335916011864	putative 5' ssDNA interaction site; other site
1335916011865	metal binding site 3; metal-binding site
1335916011866	metal binding site 2 [ion binding]; metal-binding site
1335916011867	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1335916011868	putative DNA binding site [nucleotide binding]; other site
1335916011869	putative metal binding site [ion binding]; other site
1335916011870	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1335916011871	active site
1335916011872	catalytic site [active]
1335916011873	substrate binding site [chemical binding]; other site
1335916011874	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1335916011875	active site
1335916011876	DNA binding site [nucleotide binding]
1335916011877	catalytic site [active]
1335916011878	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1335916011879	G1 box; other site
1335916011880	GTP/Mg2+ binding site [chemical binding]; other site
1335916011881	Switch I region; other site
1335916011882	G2 box; other site
1335916011883	G3 box; other site
1335916011884	Switch II region; other site
1335916011885	G4 box; other site
1335916011886	G5 box; other site
1335916011887	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
1335916011888	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1335916011889	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916011890	FeS/SAM binding site; other site
1335916011891	HemN C-terminal domain; Region: HemN_C; pfam06969
1335916011892	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
1335916011893	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916011894	active site
1335916011895	phosphorylation site [posttranslational modification]
1335916011896	intermolecular recognition site; other site
1335916011897	dimerization interface [polypeptide binding]; other site
1335916011898	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916011899	Walker A motif; other site
1335916011900	ATP binding site [chemical binding]; other site
1335916011901	Walker B motif; other site
1335916011902	arginine finger; other site
1335916011903	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1335916011904	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
1335916011905	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1335916011906	putative active site [active]
1335916011907	heme pocket [chemical binding]; other site
1335916011908	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916011909	dimer interface [polypeptide binding]; other site
1335916011910	phosphorylation site [posttranslational modification]
1335916011911	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916011912	ATP binding site [chemical binding]; other site
1335916011913	Mg2+ binding site [ion binding]; other site
1335916011914	G-X-G motif; other site
1335916011915	glutamine synthetase; Provisional; Region: glnA; PRK09469
1335916011916	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1335916011917	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1335916011918	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1335916011919	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1335916011920	G1 box; other site
1335916011921	putative GEF interaction site [polypeptide binding]; other site
1335916011922	GTP/Mg2+ binding site [chemical binding]; other site
1335916011923	Switch I region; other site
1335916011924	G2 box; other site
1335916011925	G3 box; other site
1335916011926	Switch II region; other site
1335916011927	G4 box; other site
1335916011928	G5 box; other site
1335916011929	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1335916011930	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1335916011931	transcriptional regulator protein; Region: phnR; TIGR03337
1335916011932	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916011933	DNA-binding site [nucleotide binding]; DNA binding site
1335916011934	UTRA domain; Region: UTRA; pfam07702
1335916011935	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1335916011936	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916011937	putative substrate translocation pore; other site
1335916011938	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
1335916011939	outer membrane porin L; Provisional; Region: ompL; PRK09980
1335916011940	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1335916011941	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916011942	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1335916011943	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1335916011944	alpha-glucosidase; Provisional; Region: PRK10426
1335916011945	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1335916011946	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
1335916011947	putative active site [active]
1335916011948	putative catalytic site [active]
1335916011949	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
1335916011950	active site
1335916011951	catalytic residues [active]
1335916011952	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
1335916011953	dimerization interface [polypeptide binding]; other site
1335916011954	putative active cleft [active]
1335916011955	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
1335916011956	catalytic residue [active]
1335916011957	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
1335916011958	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1335916011959	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1335916011960	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
1335916011961	substrate binding site [chemical binding]; other site
1335916011962	ATP binding site [chemical binding]; other site
1335916011963	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1335916011964	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1335916011965	putative DNA binding site [nucleotide binding]; other site
1335916011966	putative Zn2+ binding site [ion binding]; other site
1335916011967	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1335916011968	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1335916011969	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916011970	motif II; other site
1335916011971	hypothetical protein; Reviewed; Region: PRK01637
1335916011972	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1335916011973	putative active site [active]
1335916011974	dimerization interface [polypeptide binding]; other site
1335916011975	putative tRNAtyr binding site [nucleotide binding]; other site
1335916011976	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1335916011977	Coenzyme A binding pocket [chemical binding]; other site
1335916011978	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1335916011979	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1335916011980	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1335916011981	substrate binding pocket [chemical binding]; other site
1335916011982	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1335916011983	non-specific DNA binding site [nucleotide binding]; other site
1335916011984	salt bridge; other site
1335916011985	sequence-specific DNA binding site [nucleotide binding]; other site
1335916011986	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
1335916011987	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1335916011988	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
1335916011989	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
1335916011990	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1335916011991	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1335916011992	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1335916011993	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1335916011994	molybdopterin cofactor binding site; other site
1335916011995	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1335916011996	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1335916011997	molybdopterin cofactor binding site; other site
1335916011998	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1335916011999	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1335916012000	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
1335916012001	putative frv operon regulatory protein; Provisional; Region: PRK09863
1335916012002	HTH domain; Region: HTH_11; pfam08279
1335916012003	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1335916012004	active site
1335916012005	phosphorylation site [posttranslational modification]
1335916012006	putative peptidase; Provisional; Region: PRK09864
1335916012007	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1335916012008	oligomer interface [polypeptide binding]; other site
1335916012009	active site
1335916012010	metal binding site [ion binding]; metal-binding site
1335916012011	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
1335916012012	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1335916012013	active site
1335916012014	P-loop; other site
1335916012015	phosphorylation site [posttranslational modification]
1335916012016	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1335916012017	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1335916012018	active site
1335916012019	phosphorylation site [posttranslational modification]
1335916012020	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
1335916012021	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1335916012022	intersubunit interface [polypeptide binding]; other site
1335916012023	active site
1335916012024	Zn2+ binding site [ion binding]; other site
1335916012025	L-rhamnose isomerase; Provisional; Region: PRK01076
1335916012026	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
1335916012027	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1335916012028	N- and C-terminal domain interface [polypeptide binding]; other site
1335916012029	active site
1335916012030	putative catalytic site [active]
1335916012031	metal binding site [ion binding]; metal-binding site
1335916012032	ATP binding site [chemical binding]; other site
1335916012033	rhamnulokinase; Provisional; Region: rhaB; PRK10640
1335916012034	carbohydrate binding site [chemical binding]; other site
1335916012035	transcriptional activator RhaS; Provisional; Region: PRK13503
1335916012036	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1335916012037	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916012038	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916012039	transcriptional activator RhaR; Provisional; Region: PRK13500
1335916012040	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1335916012041	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916012042	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916012043	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
1335916012044	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
1335916012045	superoxide dismutase; Provisional; Region: PRK10925
1335916012046	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1335916012047	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1335916012048	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
1335916012049	2-keto-3-deoxygluconate transporter; Region: kdgT; TIGR00793
1335916012050	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
1335916012051	MOSC domain; Region: MOSC; pfam03473
1335916012052	3-alpha domain; Region: 3-alpha; pfam03475
1335916012053	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1335916012054	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1335916012055	dimerization interface [polypeptide binding]; other site
1335916012056	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916012057	dimer interface [polypeptide binding]; other site
1335916012058	phosphorylation site [posttranslational modification]
1335916012059	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916012060	ATP binding site [chemical binding]; other site
1335916012061	Mg2+ binding site [ion binding]; other site
1335916012062	G-X-G motif; other site
1335916012063	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1335916012064	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916012065	active site
1335916012066	intermolecular recognition site; other site
1335916012067	dimerization interface [polypeptide binding]; other site
1335916012068	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1335916012069	DNA binding site [nucleotide binding]
1335916012070	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1335916012071	dimer interface [polypeptide binding]; other site
1335916012072	integrase; Provisional; Region: int; PHA02601
1335916012073	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
1335916012074	active site
1335916012075	catalytic residues [active]
1335916012076	Int/Topo IB signature motif; other site
1335916012077	dimer interface [polypeptide binding]; other site
1335916012078	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1335916012079	non-specific DNA binding site [nucleotide binding]; other site
1335916012080	salt bridge; other site
1335916012081	sequence-specific DNA binding site [nucleotide binding]; other site
1335916012082	Regulatory phage protein cox; Region: Phage_Cox; pfam10743
1335916012083	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
1335916012084	DksA-like zinc finger domain containing protein; Region: PHA00080
1335916012085	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1335916012086	Domain of Unknown Function with PDB structure (DUF3850); Region: DUF3850; pfam12961
1335916012087	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1335916012088	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
1335916012089	cofactor binding site; other site
1335916012090	DNA binding site [nucleotide binding]
1335916012091	substrate interaction site [chemical binding]; other site
1335916012092	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1335916012093	ParB-like nuclease domain; Region: ParB; smart00470
1335916012094	portal vertex protein; Provisional; Region: Q; PHA02536
1335916012095	Phage portal protein; Region: Phage_portal; pfam04860
1335916012096	terminase ATPase subunit; Provisional; Region: P; PHA02535
1335916012097	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1335916012098	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
1335916012099	terminase endonuclease subunit; Provisional; Region: M; PHA02537
1335916012100	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1335916012101	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1335916012102	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1335916012103	Phage holin family 2; Region: Phage_holin_2; pfam04550
1335916012104	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
1335916012105	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1335916012106	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
1335916012107	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1335916012108	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1335916012109	baseplate wedge subunit; Provisional; Region: W; PHA02516
1335916012110	baseplate assembly protein; Provisional; Region: J; PHA02568
1335916012111	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1335916012112	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1335916012113	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1335916012114	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1335916012115	major tail tube protein; Provisional; Region: FII; PHA02600
1335916012116	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1335916012117	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1335916012118	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1335916012119	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
1335916012120	tail protein; Provisional; Region: D; PHA02561
1335916012121	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
1335916012122	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1335916012123	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1335916012124	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1335916012125	active site
1335916012126	ADP/pyrophosphate binding site [chemical binding]; other site
1335916012127	dimerization interface [polypeptide binding]; other site
1335916012128	allosteric effector site; other site
1335916012129	fructose-1,6-bisphosphate binding site; other site
1335916012130	sulfate transporter subunit; Provisional; Region: PRK10752
1335916012131	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1335916012132	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
1335916012133	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1335916012134	triosephosphate isomerase; Provisional; Region: PRK14567
1335916012135	substrate binding site [chemical binding]; other site
1335916012136	dimer interface [polypeptide binding]; other site
1335916012137	catalytic triad [active]
1335916012138	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
1335916012139	Predicted membrane protein [Function unknown]; Region: COG3152
1335916012140	hypothetical protein; Provisional; Region: PRK09981
1335916012141	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1335916012142	Ligand Binding Site [chemical binding]; other site
1335916012143	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1335916012144	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1335916012145	FAD binding pocket [chemical binding]; other site
1335916012146	FAD binding motif [chemical binding]; other site
1335916012147	phosphate binding motif [ion binding]; other site
1335916012148	beta-alpha-beta structure motif; other site
1335916012149	NAD binding pocket [chemical binding]; other site
1335916012150	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1335916012151	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1335916012152	putative active site [active]
1335916012153	glycerol kinase; Provisional; Region: glpK; PRK00047
1335916012154	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1335916012155	N- and C-terminal domain interface [polypeptide binding]; other site
1335916012156	active site
1335916012157	MgATP binding site [chemical binding]; other site
1335916012158	catalytic site [active]
1335916012159	metal binding site [ion binding]; metal-binding site
1335916012160	glycerol binding site [chemical binding]; other site
1335916012161	homotetramer interface [polypeptide binding]; other site
1335916012162	homodimer interface [polypeptide binding]; other site
1335916012163	FBP binding site [chemical binding]; other site
1335916012164	protein IIAGlc interface [polypeptide binding]; other site
1335916012165	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1335916012166	amphipathic channel; other site
1335916012167	Asn-Pro-Ala signature motifs; other site
1335916012168	septal ring assembly protein ZapB; Provisional; Region: PRK15422
1335916012169	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1335916012170	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
1335916012171	UbiA prenyltransferase family; Region: UbiA; pfam01040
1335916012172	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1335916012173	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916012174	Walker A motif; other site
1335916012175	ATP binding site [chemical binding]; other site
1335916012176	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1335916012177	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1335916012178	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1335916012179	active site
1335916012180	HslU subunit interaction site [polypeptide binding]; other site
1335916012181	essential cell division protein FtsN; Provisional; Region: PRK10927
1335916012182	cell division protein FtsN; Provisional; Region: PRK12757
1335916012183	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1335916012184	DNA binding site [nucleotide binding]
1335916012185	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1335916012186	domain linker motif; other site
1335916012187	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1335916012188	dimerization interface [polypeptide binding]; other site
1335916012189	ligand binding site [chemical binding]; other site
1335916012190	primosome assembly protein PriA; Validated; Region: PRK05580
1335916012191	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1335916012192	ATP binding site [chemical binding]; other site
1335916012193	putative Mg++ binding site [ion binding]; other site
1335916012194	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1335916012195	ATP-binding site [chemical binding]; other site
1335916012196	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1335916012197	PAAR motif; Region: PAAR_motif; cl15808
1335916012198	RHS Repeat; Region: RHS_repeat; cl11982
1335916012199	RHS Repeat; Region: RHS_repeat; pfam05593
1335916012200	RHS Repeat; Region: RHS_repeat; cl11982
1335916012201	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1335916012202	RHS Repeat; Region: RHS_repeat; pfam05593
1335916012203	RHS Repeat; Region: RHS_repeat; pfam05593
1335916012204	RHS protein; Region: RHS; pfam03527
1335916012205	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1335916012206	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
1335916012207	hypothetical protein; Provisional; Region: PRK10030
1335916012208	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1335916012209	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1335916012210	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1335916012211	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1335916012212	dimerization interface [polypeptide binding]; other site
1335916012213	DNA binding site [nucleotide binding]
1335916012214	corepressor binding sites; other site
1335916012215	cystathionine gamma-synthase; Provisional; Region: PRK08045
1335916012216	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1335916012217	homodimer interface [polypeptide binding]; other site
1335916012218	substrate-cofactor binding pocket; other site
1335916012219	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916012220	catalytic residue [active]
1335916012221	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1335916012222	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1335916012223	putative catalytic residues [active]
1335916012224	putative nucleotide binding site [chemical binding]; other site
1335916012225	putative aspartate binding site [chemical binding]; other site
1335916012226	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
1335916012227	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1335916012228	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1335916012229	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1335916012230	FAD binding site [chemical binding]; other site
1335916012231	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
1335916012232	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1335916012233	heme binding site [chemical binding]; other site
1335916012234	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
1335916012235	EamA-like transporter family; Region: EamA; pfam00892
1335916012236	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1335916012237	EamA-like transporter family; Region: EamA; pfam00892
1335916012238	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
1335916012239	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1335916012240	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1335916012241	dimer interface [polypeptide binding]; other site
1335916012242	active site
1335916012243	metal binding site [ion binding]; metal-binding site
1335916012244	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1335916012245	active site
1335916012246	intersubunit interactions; other site
1335916012247	catalytic residue [active]
1335916012248	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1335916012249	dimerization domain swap beta strand [polypeptide binding]; other site
1335916012250	regulatory protein interface [polypeptide binding]; other site
1335916012251	active site
1335916012252	regulatory phosphorylation site [posttranslational modification]; other site
1335916012253	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1335916012254	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1335916012255	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1335916012256	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1335916012257	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1335916012258	active site
1335916012259	phosphorylation site [posttranslational modification]
1335916012260	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
1335916012261	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1335916012262	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1335916012263	active site
1335916012264	P-loop; other site
1335916012265	phosphorylation site [posttranslational modification]
1335916012266	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
1335916012267	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1335916012268	dimer interface [polypeptide binding]; other site
1335916012269	active site
1335916012270	glycine loop; other site
1335916012271	pyruvate formate lyase II activase; Provisional; Region: PRK10076
1335916012272	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1335916012273	active site
1335916012274	P-loop; other site
1335916012275	phosphorylation site [posttranslational modification]
1335916012276	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1335916012277	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916012278	hypothetical protein; Provisional; Region: PRK10649
1335916012279	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1335916012280	Sulfatase; Region: Sulfatase; pfam00884
1335916012281	acetylornithine deacetylase; Provisional; Region: PRK05111
1335916012282	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1335916012283	metal binding site [ion binding]; metal-binding site
1335916012284	putative dimer interface [polypeptide binding]; other site
1335916012285	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1335916012286	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1335916012287	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
1335916012288	nucleotide binding site [chemical binding]; other site
1335916012289	N-acetyl-L-glutamate binding site [chemical binding]; other site
1335916012290	argininosuccinate lyase; Provisional; Region: PRK04833
1335916012291	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1335916012292	active sites [active]
1335916012293	tetramer interface [polypeptide binding]; other site
1335916012294	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1335916012295	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916012296	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1335916012297	dimerization interface [polypeptide binding]; other site
1335916012298	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1335916012299	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1335916012300	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1335916012301	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1335916012302	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1335916012303	hypothetical protein; Provisional; Region: PRK11056
1335916012304	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1335916012305	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916012306	S-adenosylmethionine binding site [chemical binding]; other site
1335916012307	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
1335916012308	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1335916012309	N-terminal plug; other site
1335916012310	ligand-binding site [chemical binding]; other site
1335916012311	glutamate racemase; Provisional; Region: PRK00865
1335916012312	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1335916012313	FAD binding domain; Region: FAD_binding_4; pfam01565
1335916012314	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1335916012315	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1335916012316	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1335916012317	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1335916012318	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1335916012319	pantothenate kinase; Provisional; Region: PRK05439
1335916012320	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1335916012321	ATP-binding site [chemical binding]; other site
1335916012322	CoA-binding site [chemical binding]; other site
1335916012323	Mg2+-binding site [ion binding]; other site
1335916012324	elongation factor Tu; Reviewed; Region: PRK00049
1335916012325	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1335916012326	G1 box; other site
1335916012327	GEF interaction site [polypeptide binding]; other site
1335916012328	GTP/Mg2+ binding site [chemical binding]; other site
1335916012329	Switch I region; other site
1335916012330	G2 box; other site
1335916012331	G3 box; other site
1335916012332	Switch II region; other site
1335916012333	G4 box; other site
1335916012334	G5 box; other site
1335916012335	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1335916012336	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1335916012337	Antibiotic Binding Site [chemical binding]; other site
1335916012338	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1335916012339	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1335916012340	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1335916012341	putative homodimer interface [polypeptide binding]; other site
1335916012342	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1335916012343	heterodimer interface [polypeptide binding]; other site
1335916012344	homodimer interface [polypeptide binding]; other site
1335916012345	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1335916012346	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1335916012347	23S rRNA interface [nucleotide binding]; other site
1335916012348	L7/L12 interface [polypeptide binding]; other site
1335916012349	putative thiostrepton binding site; other site
1335916012350	L25 interface [polypeptide binding]; other site
1335916012351	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1335916012352	mRNA/rRNA interface [nucleotide binding]; other site
1335916012353	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1335916012354	23S rRNA interface [nucleotide binding]; other site
1335916012355	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1335916012356	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1335916012357	core dimer interface [polypeptide binding]; other site
1335916012358	peripheral dimer interface [polypeptide binding]; other site
1335916012359	L10 interface [polypeptide binding]; other site
1335916012360	L11 interface [polypeptide binding]; other site
1335916012361	putative EF-Tu interaction site [polypeptide binding]; other site
1335916012362	putative EF-G interaction site [polypeptide binding]; other site
1335916012363	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1335916012364	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1335916012365	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1335916012366	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1335916012367	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1335916012368	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1335916012369	RPB3 interaction site [polypeptide binding]; other site
1335916012370	RPB1 interaction site [polypeptide binding]; other site
1335916012371	RPB11 interaction site [polypeptide binding]; other site
1335916012372	RPB10 interaction site [polypeptide binding]; other site
1335916012373	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1335916012374	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1335916012375	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1335916012376	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1335916012377	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1335916012378	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1335916012379	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1335916012380	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1335916012381	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1335916012382	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1335916012383	DNA binding site [nucleotide binding]
1335916012384	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1335916012385	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
1335916012386	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916012387	FeS/SAM binding site; other site
1335916012388	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1335916012389	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1335916012390	ThiS interaction site; other site
1335916012391	putative active site [active]
1335916012392	tetramer interface [polypeptide binding]; other site
1335916012393	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1335916012394	thiS-thiF/thiG interaction site; other site
1335916012395	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1335916012396	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
1335916012397	ATP binding site [chemical binding]; other site
1335916012398	substrate interface [chemical binding]; other site
1335916012399	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1335916012400	thiamine phosphate binding site [chemical binding]; other site
1335916012401	active site
1335916012402	pyrophosphate binding site [ion binding]; other site
1335916012403	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1335916012404	ThiC-associated domain; Region: ThiC-associated; pfam13667
1335916012405	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1335916012406	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
1335916012407	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
1335916012408	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
1335916012409	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1335916012410	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1335916012411	putative NADH binding site [chemical binding]; other site
1335916012412	putative active site [active]
1335916012413	nudix motif; other site
1335916012414	putative metal binding site [ion binding]; other site
1335916012415	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1335916012416	substrate binding site [chemical binding]; other site
1335916012417	active site
1335916012418	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
1335916012419	Active_site [active]
1335916012420	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
1335916012421	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1335916012422	IHF dimer interface [polypeptide binding]; other site
1335916012423	IHF - DNA interface [nucleotide binding]; other site
1335916012424	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
1335916012425	zinc resistance protein; Provisional; Region: zraP; PRK11546
1335916012426	dimer interface [polypeptide binding]; other site
1335916012427	sensor protein ZraS; Provisional; Region: PRK10364
1335916012428	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916012429	dimer interface [polypeptide binding]; other site
1335916012430	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916012431	ATP binding site [chemical binding]; other site
1335916012432	Mg2+ binding site [ion binding]; other site
1335916012433	G-X-G motif; other site
1335916012434	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
1335916012435	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916012436	active site
1335916012437	phosphorylation site [posttranslational modification]
1335916012438	intermolecular recognition site; other site
1335916012439	dimerization interface [polypeptide binding]; other site
1335916012440	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916012441	Walker A motif; other site
1335916012442	ATP binding site [chemical binding]; other site
1335916012443	Walker B motif; other site
1335916012444	arginine finger; other site
1335916012445	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1335916012446	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1335916012447	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1335916012448	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1335916012449	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1335916012450	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1335916012451	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1335916012452	purine monophosphate binding site [chemical binding]; other site
1335916012453	dimer interface [polypeptide binding]; other site
1335916012454	putative catalytic residues [active]
1335916012455	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1335916012456	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
1335916012457	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
1335916012458	dimer interface [polypeptide binding]; other site
1335916012459	PYR/PP interface [polypeptide binding]; other site
1335916012460	TPP binding site [chemical binding]; other site
1335916012461	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1335916012462	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
1335916012463	TPP-binding site [chemical binding]; other site
1335916012464	dimer interface [polypeptide binding]; other site
1335916012465	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
1335916012466	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1335916012467	NAD binding site [chemical binding]; other site
1335916012468	substrate binding site [chemical binding]; other site
1335916012469	catalytic Zn binding site [ion binding]; other site
1335916012470	tetramer interface [polypeptide binding]; other site
1335916012471	structural Zn binding site [ion binding]; other site
1335916012472	putative alcohol dehydrogenase; Provisional; Region: PRK09860
1335916012473	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1335916012474	dimer interface [polypeptide binding]; other site
1335916012475	active site
1335916012476	metal binding site [ion binding]; metal-binding site
1335916012477	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1335916012478	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1335916012479	Coenzyme A binding pocket [chemical binding]; other site
1335916012480	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1335916012481	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1335916012482	proposed active site lysine [active]
1335916012483	conserved cys residue [active]
1335916012484	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1335916012485	malate synthase A; Region: malate_syn_A; TIGR01344
1335916012486	active site
1335916012487	isocitrate lyase; Provisional; Region: PRK15063
1335916012488	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1335916012489	tetramer interface [polypeptide binding]; other site
1335916012490	active site
1335916012491	Mg2+/Mn2+ binding site [ion binding]; other site
1335916012492	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
1335916012493	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
1335916012494	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
1335916012495	transcriptional repressor IclR; Provisional; Region: PRK11569
1335916012496	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1335916012497	Bacterial transcriptional regulator; Region: IclR; pfam01614
1335916012498	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1335916012499	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1335916012500	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1335916012501	substrate binding pocket [chemical binding]; other site
1335916012502	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1335916012503	B12 binding site [chemical binding]; other site
1335916012504	cobalt ligand [ion binding]; other site
1335916012505	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1335916012506	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1335916012507	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1335916012508	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1335916012509	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1335916012510	active site pocket [active]
1335916012511	oxyanion hole [active]
1335916012512	catalytic triad [active]
1335916012513	active site nucleophile [active]
1335916012514	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
1335916012515	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1335916012516	RNA binding surface [nucleotide binding]; other site
1335916012517	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1335916012518	probable active site [active]
1335916012519	hypothetical protein; Provisional; Region: PRK10515
1335916012520	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1335916012521	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1335916012522	Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127
1335916012523	Zeta toxin; Region: Zeta_toxin; pfam06414
1335916012524	aspartate kinase III; Validated; Region: PRK09084
1335916012525	AAK_AKiii-LysC-EC: Amino Acid Kinase Superfamily (AAK), AKiii-LysC-EC: this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKIII. AKIII is a monofunctional class enzyme (LysC) found in some...; Region: AAK_AKiii-LysC-EC; cd04258
1335916012526	nucleotide binding site [chemical binding]; other site
1335916012527	putative catalytic residues [active]
1335916012528	aspartate binding site [chemical binding]; other site
1335916012529	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
1335916012530	lysine allosteric regulatory site; other site
1335916012531	dimer interface [polypeptide binding]; other site
1335916012532	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1335916012533	dimer interface [polypeptide binding]; other site
1335916012534	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1335916012535	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1335916012536	active site
1335916012537	dimer interface [polypeptide binding]; other site
1335916012538	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1335916012539	dimer interface [polypeptide binding]; other site
1335916012540	active site
1335916012541	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
1335916012542	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
1335916012543	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
1335916012544	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
1335916012545	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
1335916012546	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
1335916012547	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916012548	putative substrate translocation pore; other site
1335916012549	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916012550	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1335916012551	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916012552	dimer interface [polypeptide binding]; other site
1335916012553	conserved gate region; other site
1335916012554	putative PBP binding loops; other site
1335916012555	ABC-ATPase subunit interface; other site
1335916012556	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1335916012557	dimer interface [polypeptide binding]; other site
1335916012558	conserved gate region; other site
1335916012559	putative PBP binding loops; other site
1335916012560	ABC-ATPase subunit interface; other site
1335916012561	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
1335916012562	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
1335916012563	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1335916012564	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
1335916012565	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1335916012566	Walker A/P-loop; other site
1335916012567	ATP binding site [chemical binding]; other site
1335916012568	Q-loop/lid; other site
1335916012569	ABC transporter signature motif; other site
1335916012570	Walker B; other site
1335916012571	D-loop; other site
1335916012572	H-loop/switch region; other site
1335916012573	TOBE domain; Region: TOBE_2; pfam08402
1335916012574	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1335916012575	trimer interface; other site
1335916012576	sugar binding site [chemical binding]; other site
1335916012577	maltose regulon periplasmic protein; Provisional; Region: PRK10564
1335916012578	hypothetical protein; Validated; Region: PRK09718
1335916012579	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
1335916012580	SopA-like central domain; Region: SopA; pfam13981
1335916012581	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
1335916012582	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
1335916012583	UbiA prenyltransferase family; Region: UbiA; pfam01040
1335916012584	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
1335916012585	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1335916012586	putative acyl-acceptor binding pocket; other site
1335916012587	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1335916012588	LexA repressor; Validated; Region: PRK00215
1335916012589	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1335916012590	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1335916012591	Catalytic site [active]
1335916012592	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
1335916012593	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1335916012594	hypothetical protein; Provisional; Region: PRK10428
1335916012595	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1335916012596	metal binding site 2 [ion binding]; metal-binding site
1335916012597	putative DNA binding helix; other site
1335916012598	metal binding site 1 [ion binding]; metal-binding site
1335916012599	dimer interface [polypeptide binding]; other site
1335916012600	structural Zn2+ binding site [ion binding]; other site
1335916012601	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
1335916012602	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1335916012603	FMN binding site [chemical binding]; other site
1335916012604	active site
1335916012605	catalytic residues [active]
1335916012606	substrate binding site [chemical binding]; other site
1335916012607	phage shock protein G; Reviewed; Region: pspG; PRK09459
1335916012608	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1335916012609	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1335916012610	NADP binding site [chemical binding]; other site
1335916012611	dimer interface [polypeptide binding]; other site
1335916012612	replicative DNA helicase; Provisional; Region: PRK08006
1335916012613	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1335916012614	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1335916012615	Walker A motif; other site
1335916012616	ATP binding site [chemical binding]; other site
1335916012617	Walker B motif; other site
1335916012618	DNA binding loops [nucleotide binding]
1335916012619	alanine racemase; Reviewed; Region: alr; PRK00053
1335916012620	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1335916012621	active site
1335916012622	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1335916012623	substrate binding site [chemical binding]; other site
1335916012624	catalytic residues [active]
1335916012625	dimer interface [polypeptide binding]; other site
1335916012626	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1335916012627	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1335916012628	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916012629	homodimer interface [polypeptide binding]; other site
1335916012630	catalytic residue [active]
1335916012631	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916012632	active site
1335916012633	motif I; other site
1335916012634	motif II; other site
1335916012635	Uncharacterized protein family UPF0047; Region: UPF0047; cl00439
1335916012636	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1335916012637	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1335916012638	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1335916012639	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1335916012640	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1335916012641	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1335916012642	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1335916012643	dimer interface [polypeptide binding]; other site
1335916012644	ssDNA binding site [nucleotide binding]; other site
1335916012645	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1335916012646	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
1335916012647	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1335916012648	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1335916012649	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1335916012650	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1335916012651	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916012652	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
1335916012653	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
1335916012654	DNA binding residues [nucleotide binding]
1335916012655	dimer interface [polypeptide binding]; other site
1335916012656	[2Fe-2S] cluster binding site [ion binding]; other site
1335916012657	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1335916012658	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1335916012659	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1335916012660	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1335916012661	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1335916012662	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1335916012663	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1335916012664	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1335916012665	Na binding site [ion binding]; other site
1335916012666	Predicted membrane protein [Function unknown]; Region: COG3162
1335916012667	acetyl-CoA synthetase; Provisional; Region: PRK00174
1335916012668	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1335916012669	active site
1335916012670	CoA binding site [chemical binding]; other site
1335916012671	acyl-activating enzyme (AAE) consensus motif; other site
1335916012672	AMP binding site [chemical binding]; other site
1335916012673	acetate binding site [chemical binding]; other site
1335916012674	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
1335916012675	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
1335916012676	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
1335916012677	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
1335916012678	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
1335916012679	heme lyase subunit NrfE; Provisional; Region: PRK10369
1335916012680	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
1335916012681	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
1335916012682	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1335916012683	binding surface
1335916012684	TPR motif; other site
1335916012685	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
1335916012686	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1335916012687	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1335916012688	Sel1-like repeats; Region: SEL1; smart00671
1335916012689	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1335916012690	molybdopterin cofactor binding site; other site
1335916012691	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1335916012692	molybdopterin cofactor binding site; other site
1335916012693	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1335916012694	putative outer membrane efflux protein MdtP; Provisional; Region: PRK09915
1335916012695	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
1335916012696	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1335916012697	multidrug resistance protein MdtN; Provisional; Region: PRK10476
1335916012698	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1335916012699	HlyD family secretion protein; Region: HlyD_3; pfam13437
1335916012700	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1335916012701	D-allose kinase; Provisional; Region: PRK09698
1335916012702	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1335916012703	nucleotide binding site [chemical binding]; other site
1335916012704	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1335916012705	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1335916012706	substrate binding site [chemical binding]; other site
1335916012707	hexamer interface [polypeptide binding]; other site
1335916012708	metal binding site [ion binding]; metal-binding site
1335916012709	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1335916012710	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1335916012711	TM-ABC transporter signature motif; other site
1335916012712	D-allose transporter ATP-binding protein; Provisional; Region: PRK09700
1335916012713	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916012714	Walker A/P-loop; other site
1335916012715	ATP binding site [chemical binding]; other site
1335916012716	Q-loop/lid; other site
1335916012717	ABC transporter signature motif; other site
1335916012718	Walker B; other site
1335916012719	D-loop; other site
1335916012720	H-loop/switch region; other site
1335916012721	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1335916012722	D-allose transporter subunit; Provisional; Region: PRK09701
1335916012723	Periplasmic allose-binding domain of bacterial transport systems that function as a primary receptor of active transport and chemotaxis; Region: PBP1_allose_binding; cd06320
1335916012724	ligand binding site [chemical binding]; other site
1335916012725	dimerization interface [polypeptide binding]; other site
1335916012726	zinc binding site [ion binding]; other site
1335916012727	DNA-binding transcriptional repressor RpiR; Provisional; Region: PRK11337
1335916012728	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1335916012729	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1335916012730	putative active site [active]
1335916012731	ribose 5-phosphate isomerase B; Region: rpiB; TIGR01120
1335916012732	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
1335916012733	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1335916012734	Coenzyme A binding pocket [chemical binding]; other site
1335916012735	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
1335916012736	AAA domain; Region: AAA_18; pfam13238
1335916012737	active site
1335916012738	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
1335916012739	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1335916012740	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
1335916012741	active site
1335916012742	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
1335916012743	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1335916012744	Walker A/P-loop; other site
1335916012745	ATP binding site [chemical binding]; other site
1335916012746	Q-loop/lid; other site
1335916012747	ABC transporter signature motif; other site
1335916012748	Walker B; other site
1335916012749	D-loop; other site
1335916012750	H-loop/switch region; other site
1335916012751	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
1335916012752	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1335916012753	Walker A/P-loop; other site
1335916012754	ATP binding site [chemical binding]; other site
1335916012755	Q-loop/lid; other site
1335916012756	ABC transporter signature motif; other site
1335916012757	Walker B; other site
1335916012758	D-loop; other site
1335916012759	H-loop/switch region; other site
1335916012760	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1335916012761	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnJ; COG3627
1335916012762	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnI; COG3626
1335916012763	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnH; COG3625
1335916012764	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
1335916012765	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
1335916012766	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916012767	DNA-binding site [nucleotide binding]; DNA binding site
1335916012768	UTRA domain; Region: UTRA; pfam07702
1335916012769	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
1335916012770	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1335916012771	substrate binding pocket [chemical binding]; other site
1335916012772	membrane-bound complex binding site; other site
1335916012773	hinge residues; other site
1335916012774	phosphonate/organophosphate ester transporter subunit; Provisional; Region: PRK09984
1335916012775	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
1335916012776	Walker A/P-loop; other site
1335916012777	ATP binding site [chemical binding]; other site
1335916012778	Q-loop/lid; other site
1335916012779	ABC transporter signature motif; other site
1335916012780	Walker B; other site
1335916012781	D-loop; other site
1335916012782	H-loop/switch region; other site
1335916012783	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1335916012784	dimer interface [polypeptide binding]; other site
1335916012785	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1335916012786	hypothetical protein; Provisional; Region: PRK10220
1335916012787	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1335916012788	PhnA protein; Region: PhnA; pfam03831
1335916012789	hypothetical protein; Provisional; Region: PRK09866
1335916012790	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1335916012791	G1 box; other site
1335916012792	GTP/Mg2+ binding site [chemical binding]; other site
1335916012793	G2 box; other site
1335916012794	Switch I region; other site
1335916012795	G3 box; other site
1335916012796	Switch II region; other site
1335916012797	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1335916012798	G2 box; other site
1335916012799	Switch I region; other site
1335916012800	G3 box; other site
1335916012801	Switch II region; other site
1335916012802	G4 box; other site
1335916012803	G5 box; other site
1335916012804	YjcZ-like protein; Region: YjcZ; pfam13990
1335916012805	proline/glycine betaine transporter; Provisional; Region: PRK10642
1335916012806	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916012807	putative substrate translocation pore; other site
1335916012808	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
1335916012809	sensor protein BasS/PmrB; Provisional; Region: PRK10755
1335916012810	HAMP domain; Region: HAMP; pfam00672
1335916012811	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916012812	dimer interface [polypeptide binding]; other site
1335916012813	phosphorylation site [posttranslational modification]
1335916012814	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916012815	ATP binding site [chemical binding]; other site
1335916012816	Mg2+ binding site [ion binding]; other site
1335916012817	G-X-G motif; other site
1335916012818	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1335916012819	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916012820	active site
1335916012821	phosphorylation site [posttranslational modification]
1335916012822	intermolecular recognition site; other site
1335916012823	dimerization interface [polypeptide binding]; other site
1335916012824	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1335916012825	DNA binding site [nucleotide binding]
1335916012826	putative metal dependent hydrolase; Provisional; Region: PRK11598
1335916012827	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1335916012828	Sulfatase; Region: Sulfatase; pfam00884
1335916012829	arginine:agmatin antiporter; Provisional; Region: PRK10644
1335916012830	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1335916012831	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916012832	arginine decarboxylase; Provisional; Region: PRK15029
1335916012833	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1335916012834	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1335916012835	homodimer interface [polypeptide binding]; other site
1335916012836	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916012837	catalytic residue [active]
1335916012838	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1335916012839	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
1335916012840	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916012841	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916012842	alpha-galactosidase; Provisional; Region: PRK15076
1335916012843	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
1335916012844	NAD binding site [chemical binding]; other site
1335916012845	sugar binding site [chemical binding]; other site
1335916012846	divalent metal binding site [ion binding]; other site
1335916012847	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1335916012848	dimer interface [polypeptide binding]; other site
1335916012849	melibiose:sodium symporter; Provisional; Region: PRK10429
1335916012850	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1335916012851	hypothetical protein; Provisional; Region: PRK09867
1335916012852	fumarate hydratase; Provisional; Region: PRK15389
1335916012853	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1335916012854	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1335916012855	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1335916012856	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
1335916012857	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
1335916012858	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916012859	active site
1335916012860	phosphorylation site [posttranslational modification]
1335916012861	intermolecular recognition site; other site
1335916012862	dimerization interface [polypeptide binding]; other site
1335916012863	Transcriptional regulator; Region: CitT; pfam12431
1335916012864	sensory histidine kinase DcuS; Provisional; Region: PRK11086
1335916012865	PAS domain; Region: PAS; smart00091
1335916012866	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916012867	ATP binding site [chemical binding]; other site
1335916012868	Mg2+ binding site [ion binding]; other site
1335916012869	G-X-G motif; other site
1335916012870	Uncharacterized conserved protein [Function unknown]; Region: COG3592
1335916012871	Predicted acetyltransferase [General function prediction only]; Region: COG2388
1335916012872	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
1335916012873	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1335916012874	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
1335916012875	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1335916012876	dimer interface [polypeptide binding]; other site
1335916012877	putative anticodon binding site; other site
1335916012878	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1335916012879	motif 1; other site
1335916012880	active site
1335916012881	motif 2; other site
1335916012882	motif 3; other site
1335916012883	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1335916012884	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916012885	putative substrate translocation pore; other site
1335916012886	POT family; Region: PTR2; pfam00854
1335916012887	lysine decarboxylase CadA; Provisional; Region: PRK15400
1335916012888	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1335916012889	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1335916012890	homodimer interface [polypeptide binding]; other site
1335916012891	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916012892	catalytic residue [active]
1335916012893	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1335916012894	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
1335916012895	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
1335916012896	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1335916012897	DNA binding site [nucleotide binding]
1335916012898	putative transcriptional regulator; Provisional; Region: PRK11640
1335916012899	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1335916012900	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
1335916012901	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1335916012902	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1335916012903	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1335916012904	DsbD alpha interface [polypeptide binding]; other site
1335916012905	catalytic residues [active]
1335916012906	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
1335916012907	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1335916012908	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1335916012909	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1335916012910	Aspartase; Region: Aspartase; cd01357
1335916012911	active sites [active]
1335916012912	tetramer interface [polypeptide binding]; other site
1335916012913	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
1335916012914	putative transporter; Provisional; Region: PRK11021
1335916012915	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1335916012916	oligomerisation interface [polypeptide binding]; other site
1335916012917	mobile loop; other site
1335916012918	roof hairpin; other site
1335916012919	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1335916012920	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1335916012921	ring oligomerisation interface [polypeptide binding]; other site
1335916012922	ATP/Mg binding site [chemical binding]; other site
1335916012923	stacking interactions; other site
1335916012924	hinge regions; other site
1335916012925	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1335916012926	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
1335916012927	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916012928	FeS/SAM binding site; other site
1335916012929	elongation factor P; Validated; Region: PRK00529
1335916012930	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1335916012931	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1335916012932	RNA binding site [nucleotide binding]; other site
1335916012933	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1335916012934	RNA binding site [nucleotide binding]; other site
1335916012935	entericidin A; Provisional; Region: PRK09810
1335916012936	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
1335916012937	multidrug efflux system protein; Provisional; Region: PRK11431
1335916012938	Bacterial lipocalin [Cell envelope biogenesis, outer membrane]; Region: Blc; COG3040
1335916012939	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1335916012940	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
1335916012941	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1335916012942	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
1335916012943	Iron-sulfur protein interface; other site
1335916012944	proximal quinone binding site [chemical binding]; other site
1335916012945	C-subunit interface; other site
1335916012946	distal quinone binding site; other site
1335916012947	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
1335916012948	D-subunit interface [polypeptide binding]; other site
1335916012949	proximal quinone binding site [chemical binding]; other site
1335916012950	distal quinone binding site [chemical binding]; other site
1335916012951	Glycosyl hydrolases family 8; Region: Glyco_hydro_8; pfam01270
1335916012952	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
1335916012953	L-aspartate oxidase; Provisional; Region: PRK06175
1335916012954	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1335916012955	poxB regulator PoxA; Provisional; Region: PRK09350
1335916012956	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1335916012957	motif 1; other site
1335916012958	dimer interface [polypeptide binding]; other site
1335916012959	active site
1335916012960	motif 2; other site
1335916012961	motif 3; other site
1335916012962	inner membrane transporter YjeM; Provisional; Region: PRK15238
1335916012963	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
1335916012964	putative mechanosensitive channel protein; Provisional; Region: PRK10929
1335916012965	linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated...; Region: H15; cl00073
1335916012966	DNA-binding site [nucleotide binding]; DNA binding site
1335916012967	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1335916012968	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1335916012969	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1335916012970	GTPase RsgA; Reviewed; Region: PRK12288
1335916012971	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1335916012972	RNA binding site [nucleotide binding]; other site
1335916012973	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1335916012974	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1335916012975	GTP/Mg2+ binding site [chemical binding]; other site
1335916012976	G4 box; other site
1335916012977	G5 box; other site
1335916012978	G1 box; other site
1335916012979	Switch I region; other site
1335916012980	G2 box; other site
1335916012981	G3 box; other site
1335916012982	Switch II region; other site
1335916012983	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1335916012984	catalytic site [active]
1335916012985	putative active site [active]
1335916012986	putative substrate binding site [chemical binding]; other site
1335916012987	dimer interface [polypeptide binding]; other site
1335916012988	epoxyqueuosine reductase; Region: TIGR00276
1335916012989	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1335916012990	putative carbohydrate kinase; Provisional; Region: PRK10565
1335916012991	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
1335916012992	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1335916012993	putative substrate binding site [chemical binding]; other site
1335916012994	putative ATP binding site [chemical binding]; other site
1335916012995	ADP-binding protein; Provisional; Region: PRK10646
1335916012996	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1335916012997	AMIN domain; Region: AMIN; pfam11741
1335916012998	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1335916012999	active site
1335916013000	metal binding site [ion binding]; metal-binding site
1335916013001	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1335916013002	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916013003	ATP binding site [chemical binding]; other site
1335916013004	Mg2+ binding site [ion binding]; other site
1335916013005	G-X-G motif; other site
1335916013006	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
1335916013007	ATP binding site [chemical binding]; other site
1335916013008	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1335916013009	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1335916013010	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1335916013011	bacterial Hfq-like; Region: Hfq; cd01716
1335916013012	hexamer interface [polypeptide binding]; other site
1335916013013	Sm1 motif; other site
1335916013014	RNA binding site [nucleotide binding]; other site
1335916013015	Sm2 motif; other site
1335916013016	GTPase HflX; Provisional; Region: PRK11058
1335916013017	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1335916013018	HflX GTPase family; Region: HflX; cd01878
1335916013019	G1 box; other site
1335916013020	GTP/Mg2+ binding site [chemical binding]; other site
1335916013021	Switch I region; other site
1335916013022	G2 box; other site
1335916013023	G3 box; other site
1335916013024	Switch II region; other site
1335916013025	G4 box; other site
1335916013026	G5 box; other site
1335916013027	FtsH protease regulator HflK; Provisional; Region: PRK10930
1335916013028	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
1335916013029	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1335916013030	FtsH protease regulator HflC; Provisional; Region: PRK11029
1335916013031	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1335916013032	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
1335916013033	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1335916013034	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1335916013035	GDP-binding site [chemical binding]; other site
1335916013036	ACT binding site; other site
1335916013037	IMP binding site; other site
1335916013038	Predicted transcriptional regulator [Transcription]; Region: COG1959
1335916013039	transcriptional repressor NsrR; Provisional; Region: PRK11014
1335916013040	exoribonuclease R; Provisional; Region: PRK11642
1335916013041	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
1335916013042	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1335916013043	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1335916013044	RNB domain; Region: RNB; pfam00773
1335916013045	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1335916013046	RNA binding site [nucleotide binding]; other site
1335916013047	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1335916013048	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1335916013049	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1335916013050	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
1335916013051	PspA/IM30 family; Region: PspA_IM30; pfam04012
1335916013052	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
1335916013053	Predicted membrane protein [Function unknown]; Region: COG3766
1335916013054	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1335916013055	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1335916013056	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1335916013057	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
1335916013058	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
1335916013059	FAD binding site [chemical binding]; other site
1335916013060	substrate binding site [chemical binding]; other site
1335916013061	catalytic residues [active]
1335916013062	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1335916013063	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
1335916013064	esterase; Provisional; Region: PRK10566
1335916013065	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1335916013066	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1335916013067	transcriptional repressor UlaR; Provisional; Region: PRK13509
1335916013068	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1335916013069	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1335916013070	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
1335916013071	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1335916013072	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
1335916013073	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
1335916013074	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1335916013075	active site
1335916013076	phosphorylation site [posttranslational modification]
1335916013077	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1335916013078	active site
1335916013079	dimer interface [polypeptide binding]; other site
1335916013080	magnesium binding site [ion binding]; other site
1335916013081	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
1335916013082	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1335916013083	AP (apurinic/apyrimidinic) site pocket; other site
1335916013084	DNA interaction; other site
1335916013085	Metal-binding active site; metal-binding site
1335916013086	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1335916013087	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1335916013088	intersubunit interface [polypeptide binding]; other site
1335916013089	active site
1335916013090	Zn2+ binding site [ion binding]; other site
1335916013091	Protein of unknown function (DUF1440); Region: DUF1440; pfam07274
1335916013092	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1335916013093	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1335916013094	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
1335916013095	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1335916013096	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1335916013097	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1335916013098	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1335916013099	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
1335916013100	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1335916013101	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1335916013102	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1335916013103	Probable transposase; Region: OrfB_IS605; pfam01385
1335916013104	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1335916013105	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
1335916013106	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1335916013107	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
1335916013108	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1335916013109	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1335916013110	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
1335916013111	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
1335916013112	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1335916013113	Hemerythrin-like domain; Region: Hr-like; cd12108
1335916013114	Fe binding site [ion binding]; other site
1335916013115	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1335916013116	EamA-like transporter family; Region: EamA; pfam00892
1335916013117	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1335916013118	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1335916013119	NADP binding site [chemical binding]; other site
1335916013120	Predicted transcriptional regulators [Transcription]; Region: COG1733
1335916013121	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1335916013122	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1335916013123	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1335916013124	active site
1335916013125	metal binding site [ion binding]; metal-binding site
1335916013126	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1335916013127	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1335916013128	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1335916013129	active site
1335916013130	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
1335916013131	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
1335916013132	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1335916013133	Domain of unknown function DUF21; Region: DUF21; pfam01595
1335916013134	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1335916013135	Transporter associated domain; Region: CorC_HlyC; smart01091
1335916013136	methionine sulfoxide reductase A; Provisional; Region: PRK00058
1335916013137	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
1335916013138	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1335916013139	Surface antigen; Region: Bac_surface_Ag; pfam01103
1335916013140	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1335916013141	putative active site pocket [active]
1335916013142	dimerization interface [polypeptide binding]; other site
1335916013143	putative catalytic residue [active]
1335916013144	antitoxin ChpS; Provisional; Region: PRK11347
1335916013145	toxin ChpB; Provisional; Region: PRK09812
1335916013146	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1335916013147	dimer interface [polypeptide binding]; other site
1335916013148	substrate binding site [chemical binding]; other site
1335916013149	metal binding sites [ion binding]; metal-binding site
1335916013150	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
1335916013151	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1335916013152	putative ligand binding site [chemical binding]; other site
1335916013153	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1335916013154	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1335916013155	Walker A/P-loop; other site
1335916013156	ATP binding site [chemical binding]; other site
1335916013157	Q-loop/lid; other site
1335916013158	ABC transporter signature motif; other site
1335916013159	Walker B; other site
1335916013160	D-loop; other site
1335916013161	H-loop/switch region; other site
1335916013162	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1335916013163	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1335916013164	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1335916013165	TM-ABC transporter signature motif; other site
1335916013166	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1335916013167	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1335916013168	TM-ABC transporter signature motif; other site
1335916013169	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1335916013170	AMP binding site [chemical binding]; other site
1335916013171	metal binding site [ion binding]; metal-binding site
1335916013172	active site
1335916013173	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1335916013174	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1335916013175	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1335916013176	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1335916013177	hypothetical protein; Provisional; Region: PRK05255
1335916013178	peptidase PmbA; Provisional; Region: PRK11040
1335916013179	cytochrome b562; Provisional; Region: PRK15058
1335916013180	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
1335916013181	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916013182	FeS/SAM binding site; other site
1335916013183	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1335916013184	ATP cone domain; Region: ATP-cone; pfam03477
1335916013185	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1335916013186	effector binding site; other site
1335916013187	active site
1335916013188	Zn binding site [ion binding]; other site
1335916013189	glycine loop; other site
1335916013190	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
1335916013191	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1335916013192	Ca binding site [ion binding]; other site
1335916013193	active site
1335916013194	catalytic site [active]
1335916013195	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
1335916013196	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1335916013197	active site turn [active]
1335916013198	phosphorylation site [posttranslational modification]
1335916013199	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1335916013200	trehalose repressor; Provisional; Region: treR; PRK09492
1335916013201	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1335916013202	DNA binding site [nucleotide binding]
1335916013203	domain linker motif; other site
1335916013204	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
1335916013205	dimerization interface [polypeptide binding]; other site
1335916013206	ligand binding site [chemical binding]; other site
1335916013207	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
1335916013208	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1335916013209	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1335916013210	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1335916013211	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916013212	motif II; other site
1335916013213	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1335916013214	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
1335916013215	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1335916013216	homotrimer interaction site [polypeptide binding]; other site
1335916013217	putative active site [active]
1335916013218	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1335916013219	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1335916013220	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1335916013221	aspartate carbamoyltransferase; Region: asp_carb_tr; TIGR00670
1335916013222	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1335916013223	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1335916013224	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
1335916013225	homotrimer interaction site [polypeptide binding]; other site
1335916013226	putative active site [active]
1335916013227	oxidoreductase; Provisional; Region: PRK12742
1335916013228	classical (c) SDRs; Region: SDR_c; cd05233
1335916013229	NAD(P) binding site [chemical binding]; other site
1335916013230	active site
1335916013231	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1335916013232	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1335916013233	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1335916013234	SopA-like central domain; Region: SopA; pfam13981
1335916013235	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1335916013236	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1335916013237	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1335916013238	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
1335916013239	RNase E inhibitor protein; Provisional; Region: PRK11191
1335916013240	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1335916013241	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1335916013242	Coenzyme A binding pocket [chemical binding]; other site
1335916013243	Predicted membrane protein [Function unknown]; Region: COG4269
1335916013244	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1335916013245	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1335916013246	HIGH motif; other site
1335916013247	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1335916013248	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1335916013249	active site
1335916013250	KMSKS motif; other site
1335916013251	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1335916013252	tRNA binding surface [nucleotide binding]; other site
1335916013253	anticodon binding site; other site
1335916013254	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1335916013255	DNA polymerase III subunit chi; Validated; Region: PRK05728
1335916013256	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1335916013257	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1335916013258	interface (dimer of trimers) [polypeptide binding]; other site
1335916013259	Substrate-binding/catalytic site; other site
1335916013260	Zn-binding sites [ion binding]; other site
1335916013261	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
1335916013262	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1335916013263	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1335916013264	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1335916013265	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
1335916013266	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1335916013267	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1335916013268	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1335916013269	DNA binding site [nucleotide binding]
1335916013270	domain linker motif; other site
1335916013271	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1335916013272	putative dimerization interface [polypeptide binding]; other site
1335916013273	putative ligand binding site [chemical binding]; other site
1335916013274	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1335916013275	gluconate transporter; Region: gntP; TIGR00791
1335916013276	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
1335916013277	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1335916013278	NADP binding site [chemical binding]; other site
1335916013279	homodimer interface [polypeptide binding]; other site
1335916013280	active site
1335916013281	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
1335916013282	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
1335916013283	putative NAD(P) binding site [chemical binding]; other site
1335916013284	catalytic Zn binding site [ion binding]; other site
1335916013285	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1335916013286	ATP-binding site [chemical binding]; other site
1335916013287	Gluconate-6-phosphate binding site [chemical binding]; other site
1335916013288	Shikimate kinase; Region: SKI; pfam01202
1335916013289	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1335916013290	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1335916013291	putative NAD(P) binding site [chemical binding]; other site
1335916013292	putative substrate binding site [chemical binding]; other site
1335916013293	catalytic Zn binding site [ion binding]; other site
1335916013294	structural Zn binding site [ion binding]; other site
1335916013295	dimer interface [polypeptide binding]; other site
1335916013296	integrase; Provisional; Region: PRK09692
1335916013297	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1335916013298	active site
1335916013299	Int/Topo IB signature motif; other site
1335916013300	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
1335916013301	HNH endonuclease; Region: HNH_2; pfam13391
1335916013302	5'-nucleotidase; Region: 5-nucleotidase; pfam06189
1335916013303	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
1335916013304	active site
1335916013305	catalytic triad [active]
1335916013306	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1335916013307	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
1335916013308	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
1335916013309	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
1335916013310	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1335916013311	ATP binding site [chemical binding]; other site
1335916013312	putative Mg++ binding site [ion binding]; other site
1335916013313	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
1335916013314	Predicted transcriptional regulator [Transcription]; Region: COG2378
1335916013315	WYL domain; Region: WYL; cl14852
1335916013316	Predicted GTPase [General function prediction only]; Region: COG3596
1335916013317	YfjP GTPase; Region: YfjP; cd11383
1335916013318	G1 box; other site
1335916013319	GTP/Mg2+ binding site [chemical binding]; other site
1335916013320	Switch I region; other site
1335916013321	G2 box; other site
1335916013322	Switch II region; other site
1335916013323	G3 box; other site
1335916013324	G4 box; other site
1335916013325	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
1335916013326	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1335916013327	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1335916013328	hypothetical protein; Reviewed; Region: PRK00024
1335916013329	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1335916013330	MPN+ (JAMM) motif; other site
1335916013331	Zinc-binding site [ion binding]; other site
1335916013332	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1335916013333	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1335916013334	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1335916013335	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
1335916013336	integrase; Provisional; Region: PRK09692
1335916013337	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1335916013338	active site
1335916013339	Int/Topo IB signature motif; other site
1335916013340	Protein kinase domain; Region: Pkinase; pfam00069
1335916013341	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1335916013342	active site
1335916013343	ATP binding site [chemical binding]; other site
1335916013344	substrate binding site [chemical binding]; other site
1335916013345	activation loop (A-loop); other site
1335916013346	HerA helicase [Replication, recombination, and repair]; Region: COG0433
1335916013347	Domain of unknown function DUF87; Region: DUF87; pfam01935
1335916013348	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1335916013349	McrBC 5-methylcytosine restriction system component; Region: McrBC; pfam10117
1335916013350	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
1335916013351	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
1335916013352	HNH endonuclease; Region: HNH_2; pfam13391
1335916013353	Domain of unknown function (DUF303); Region: DUF303; pfam03629
1335916013354	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
1335916013355	Kelch motif; Region: Kelch_1; pfam01344
1335916013356	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
1335916013357	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
1335916013358	Int/Topo IB signature motif; other site
1335916013359	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
1335916013360	Int/Topo IB signature motif; other site
1335916013361	Fimbrial protein; Region: Fimbrial; cl01416
1335916013362	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1335916013363	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1335916013364	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1335916013365	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1335916013366	outer membrane usher protein; Provisional; Region: PRK15193
1335916013367	PapC N-terminal domain; Region: PapC_N; pfam13954
1335916013368	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1335916013369	PapC C-terminal domain; Region: PapC_C; pfam13953
1335916013370	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1335916013371	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1335916013372	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
1335916013373	mannosyl binding site [chemical binding]; other site
1335916013374	Fimbrial protein; Region: Fimbrial; pfam00419
1335916013375	fructuronate transporter; Provisional; Region: PRK10034
1335916013376	gluconate transporter; Region: gntP; TIGR00791
1335916013377	mannonate dehydratase; Region: uxuA; TIGR00695
1335916013378	mannonate dehydratase; Provisional; Region: PRK03906
1335916013379	D-mannonate oxidoreductase; Provisional; Region: PRK15037
1335916013380	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1335916013381	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1335916013382	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1335916013383	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916013384	DNA-binding site [nucleotide binding]; DNA binding site
1335916013385	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1335916013386	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
1335916013387	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
1335916013388	cell density-dependent motility repressor; Provisional; Region: PRK10082
1335916013389	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1335916013390	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1335916013391	Isoaspartyl dipeptidase hydrolyzes the beta-L-isoaspartyl linkages in dipeptides, as part of the degradative pathway to eliminate proteins with beta-L-isoaspartyl peptide bonds, bonds whereby the beta-group of an aspartate forms the peptide link with the...; Region: Isoaspartyl-dipeptidase; cd01308
1335916013392	isoaspartyl dipeptidase IadA; Region: isoAsp_dipep; TIGR01975
1335916013393	dimer interface [polypeptide binding]; other site
1335916013394	active site
1335916013395	hypothetical protein; Provisional; Region: PRK10519
1335916013396	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
1335916013397	Nucleoside recognition; Region: Gate; pfam07670
1335916013398	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
1335916013399	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
1335916013400	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
1335916013401	SdiA-regulated; Region: SdiA-regulated; pfam06977
1335916013402	SdiA-regulated; Region: SdiA-regulated; cd09971
1335916013403	putative active site [active]
1335916013404	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
1335916013405	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
1335916013406	CoA-substrate-specific enzyme activase, putative; Region: CoA_E_activ; TIGR00241
1335916013407	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
1335916013408	benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263
1335916013409	Predicted membrane protein [Function unknown]; Region: COG2733
1335916013410	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
1335916013411	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916013412	putative substrate translocation pore; other site
1335916013413	putative transposase; Provisional; Region: PRK09857
1335916013414	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1335916013415	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1335916013416	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916013417	DNA-binding site [nucleotide binding]; DNA binding site
1335916013418	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1335916013419	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1335916013420	homodimer interface [polypeptide binding]; other site
1335916013421	catalytic residue [active]
1335916013422	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
1335916013423	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
1335916013424	Penicillin amidase; Region: Penicil_amidase; pfam01804
1335916013425	Penicillin G acylase (PGA) is the key enzyme in the industrial production of beta-lactam antibiotics. PGA hydrolyzes the side chain of penicillin G and related beta-lactam antibiotics releasing 6-amino penicillanic acid (6-APA), a building block in the...; Region: Ntn_PGA; cd03748
1335916013426	active site
1335916013427	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
1335916013428	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
1335916013429	P-loop, Walker A motif; other site
1335916013430	Base recognition motif; other site
1335916013431	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1335916013432	Uncharacterized small protein [Function unknown]; Region: COG2879
1335916013433	carbon starvation protein A; Provisional; Region: PRK15015
1335916013434	Carbon starvation protein CstA; Region: CstA; pfam02554
1335916013435	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1335916013436	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
1335916013437	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
1335916013438	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
1335916013439	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
1335916013440	Cupin domain; Region: Cupin_2; pfam07883
1335916013441	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916013442	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916013443	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1335916013444	putative substrate translocation pore; other site
1335916013445	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1335916013446	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
1335916013447	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
1335916013448	putative substrate binding pocket [chemical binding]; other site
1335916013449	trimer interface [polypeptide binding]; other site
1335916013450	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
1335916013451	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1335916013452	putative active site [active]
1335916013453	putative metal binding site [ion binding]; other site
1335916013454	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
1335916013455	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
1335916013456	NAD binding site [chemical binding]; other site
1335916013457	catalytic residues [active]
1335916013458	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
1335916013459	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit; Region: HpaG-N-term; TIGR02305
1335916013460	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1335916013461	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
1335916013462	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1335916013463	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1335916013464	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1335916013465	dimer interface [polypeptide binding]; other site
1335916013466	ligand binding site [chemical binding]; other site
1335916013467	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1335916013468	dimerization interface [polypeptide binding]; other site
1335916013469	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1335916013470	dimer interface [polypeptide binding]; other site
1335916013471	putative CheW interface [polypeptide binding]; other site
1335916013472	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1335916013473	D-galactonate transporter; Region: 2A0114; TIGR00893
1335916013474	putative substrate translocation pore; other site
1335916013475	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1335916013476	DNA-binding site [nucleotide binding]; DNA binding site
1335916013477	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1335916013478	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
1335916013479	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1335916013480	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1335916013481	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1335916013482	putative NAD(P) binding site [chemical binding]; other site
1335916013483	catalytic Zn binding site [ion binding]; other site
1335916013484	structural Zn binding site [ion binding]; other site
1335916013485	phosphoglycerol transferase I; Provisional; Region: PRK03776
1335916013486	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1335916013487	hypothetical protein; Provisional; Region: PRK11667
1335916013488	DNA replication protein DnaC; Validated; Region: PRK07952
1335916013489	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1335916013490	Walker A motif; other site
1335916013491	ATP binding site [chemical binding]; other site
1335916013492	Walker B motif; other site
1335916013493	primosomal protein DnaI; Provisional; Region: PRK02854
1335916013494	hypothetical protein; Provisional; Region: PRK09917
1335916013495	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1335916013496	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1335916013497	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1335916013498	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916013499	DNA binding residues [nucleotide binding]
1335916013500	dimerization interface [polypeptide binding]; other site
1335916013501	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
1335916013502	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1335916013503	DNA binding residues [nucleotide binding]
1335916013504	dimerization interface [polypeptide binding]; other site
1335916013505	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
1335916013506	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1335916013507	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
1335916013508	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
1335916013509	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1335916013510	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1335916013511	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1335916013512	S-adenosylmethionine binding site [chemical binding]; other site
1335916013513	DNA polymerase III, psi subunit [DNA replication, recombination, and repair]; Region: HolD; COG3050
1335916013514	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
1335916013515	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1335916013516	Coenzyme A binding pocket [chemical binding]; other site
1335916013517	dUMP phosphatase; Provisional; Region: PRK09449
1335916013518	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916013519	motif II; other site
1335916013520	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1335916013521	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1335916013522	G1 box; other site
1335916013523	putative GEF interaction site [polypeptide binding]; other site
1335916013524	GTP/Mg2+ binding site [chemical binding]; other site
1335916013525	Switch I region; other site
1335916013526	G2 box; other site
1335916013527	G3 box; other site
1335916013528	Switch II region; other site
1335916013529	G4 box; other site
1335916013530	G5 box; other site
1335916013531	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1335916013532	periplasmic protein; Provisional; Region: PRK10568
1335916013533	BON domain; Region: BON; pfam04972
1335916013534	BON domain; Region: BON; pfam04972
1335916013535	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1335916013536	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1335916013537	active site
1335916013538	nucleophile elbow; other site
1335916013539	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1335916013540	active site
1335916013541	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
1335916013542	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1335916013543	FeS/SAM binding site; other site
1335916013544	hypothetical protein; Provisional; Region: PRK10977
1335916013545	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1335916013546	intersubunit interface [polypeptide binding]; other site
1335916013547	active site
1335916013548	catalytic residue [active]
1335916013549	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1335916013550	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1335916013551	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1335916013552	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
1335916013553	phosphopentomutase; Provisional; Region: PRK05362
1335916013554	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1335916013555	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1335916013556	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1335916013557	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
1335916013558	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1335916013559	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1335916013560	hypothetical protein; Provisional; Region: PRK11246
1335916013561	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
1335916013562	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1335916013563	motif II; other site
1335916013564	DNA repair protein RadA; Region: sms; TIGR00416
1335916013565	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1335916013566	Walker A motif/ATP binding site; other site
1335916013567	ATP binding site [chemical binding]; other site
1335916013568	Walker B motif; other site
1335916013569	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1335916013570	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1335916013571	non-specific DNA binding site [nucleotide binding]; other site
1335916013572	salt bridge; other site
1335916013573	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1335916013574	sequence-specific DNA binding site [nucleotide binding]; other site
1335916013575	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
1335916013576	active site
1335916013577	(T/H)XGH motif; other site
1335916013578	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1335916013579	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1335916013580	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1335916013581	Walker A/P-loop; other site
1335916013582	ATP binding site [chemical binding]; other site
1335916013583	Q-loop/lid; other site
1335916013584	ABC transporter signature motif; other site
1335916013585	Walker B; other site
1335916013586	D-loop; other site
1335916013587	H-loop/switch region; other site
1335916013588	ABC transporter; Region: ABC_tran_2; pfam12848
1335916013589	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1335916013590	lytic murein transglycosylase; Provisional; Region: PRK11619
1335916013591	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1335916013592	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1335916013593	catalytic residue [active]
1335916013594	Trp operon repressor; Provisional; Region: PRK01381
1335916013595	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
1335916013596	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1335916013597	catalytic core [active]
1335916013598	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1335916013599	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1335916013600	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1335916013601	hypothetical protein; Provisional; Region: PRK10756
1335916013602	CreA protein; Region: CreA; pfam05981
1335916013603	DNA-binding response regulator CreB; Provisional; Region: PRK11083
1335916013604	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916013605	active site
1335916013606	phosphorylation site [posttranslational modification]
1335916013607	intermolecular recognition site; other site
1335916013608	dimerization interface [polypeptide binding]; other site
1335916013609	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1335916013610	DNA binding site [nucleotide binding]
1335916013611	sensory histidine kinase CreC; Provisional; Region: PRK11100
1335916013612	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1335916013613	dimerization interface [polypeptide binding]; other site
1335916013614	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1335916013615	dimer interface [polypeptide binding]; other site
1335916013616	phosphorylation site [posttranslational modification]
1335916013617	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1335916013618	ATP binding site [chemical binding]; other site
1335916013619	Mg2+ binding site [ion binding]; other site
1335916013620	G-X-G motif; other site
1335916013621	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
1335916013622	two-component response regulator; Provisional; Region: PRK11173
1335916013623	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1335916013624	active site
1335916013625	phosphorylation site [posttranslational modification]
1335916013626	intermolecular recognition site; other site
1335916013627	dimerization interface [polypeptide binding]; other site
1335916013628	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1335916013629	DNA binding site [nucleotide binding]