-- dump date   	20140619_081955
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
331111000001	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK13103
331111000002	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; Region: Spy; COG3914
331111000003	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
331111000004	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
331111000005	Protein of unknown function (DUF433); Region: DUF433; cl01030
331111000006	MULE transposase domain; Region: MULE; pfam10551
331111000007	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
331111000008	Transposase; Region: DEDD_Tnp_IS110; pfam01548
331111000009	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
331111000010	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
331111000011	Mg binding site [ion binding]; other site
331111000012	nucleotide binding site [chemical binding]; other site
331111000013	putative protofilament interface [polypeptide binding]; other site
331111000014	HNH endonuclease; Region: HNH_5; pfam14279
331111000015	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
331111000016	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111000017	salt bridge; other site
331111000018	non-specific DNA binding site [nucleotide binding]; other site
331111000019	sequence-specific DNA binding site [nucleotide binding]; other site
331111000020	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
331111000021	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000022	Transposase; Region: HTH_Tnp_1; cl17663
331111000023	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111000024	Integrase core domain; Region: rve; pfam00665
331111000025	Integrase core domain; Region: rve_3; pfam13683
331111000026	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
331111000027	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
331111000028	putative active site [active]
331111000029	putative NTP binding site [chemical binding]; other site
331111000030	putative nucleic acid binding site [nucleotide binding]; other site
331111000031	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
331111000032	putative transposase OrfB; Reviewed; Region: PHA02517
331111000033	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
331111000034	Heat-labile enterotoxin alpha chain; Region: Enterotoxin_a; pfam01375
331111000035	putative transposase OrfB; Reviewed; Region: PHA02517
331111000036	Integrase core domain; Region: rve; pfam00665
331111000037	Integrase core domain; Region: rve_3; pfam13683
331111000038	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
331111000039	Helix-turn-helix domain; Region: HTH_38; pfam13936
331111000040	Integrase core domain; Region: rve; pfam00665
331111000041	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
331111000042	ParB-like nuclease domain; Region: ParBc; pfam02195
331111000043	KorB domain; Region: KorB; pfam08535
331111000044	plasmid SOS inhibition protein B; Provisional; Region: psiB; PRK13701
331111000045	plasmid SOS inhibition protein A; Provisional; Region: PRK13704
331111000046	excinuclease ABC subunit B; Provisional; Region: PRK05298
331111000047	conjugal transfer nickase/helicase TraI; Provisional; Region: PRK14712
331111000048	conjugal transfer pilus acetylation protein TraX; Provisional; Region: PRK13706
331111000049	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
331111000050	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
331111000051	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
331111000052	conjugal transfer fertility inhibition protein FinO; Provisional; Region: PRK13754
331111000053	Fertility inhibition protein N terminal; Region: FinO_N; pfam12602
331111000054	FinO bacterial conjugation repressor domain;  the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which...; Region: FinO_conjug_rep; cd00236
331111000055	putative RNA binding sites [nucleotide binding]; other site
331111000056	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
331111000057	replication protein; Provisional; Region: PRK13750
331111000058	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
331111000059	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111000060	non-specific DNA binding site [nucleotide binding]; other site
331111000061	salt bridge; other site
331111000062	sequence-specific DNA binding site [nucleotide binding]; other site
331111000063	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
331111000064	active site
331111000065	catalytic residues [active]
331111000066	metal binding site [ion binding]; metal-binding site
331111000067	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
331111000068	Protein of unknown function (DUF535); Region: DUF535; pfam04393
331111000069	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
331111000070	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
331111000071	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
331111000072	putative active site [active]
331111000073	putative metal binding site [ion binding]; other site
331111000074	plasmid maintenance protein CcdA; Provisional; Region: PRK13710
331111000075	plasmid maintenance protein CcdB; Provisional; Region: PRK13708
331111000076	Phage integrase family; Region: Phage_integrase; pfam00589
331111000077	active site
331111000078	DNA binding site [nucleotide binding]
331111000079	Int/Topo IB signature motif; other site
331111000080	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
331111000081	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
331111000082	P-loop; other site
331111000083	Magnesium ion binding site [ion binding]; other site
331111000084	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111000085	transposase/IS protein; Provisional; Region: PRK09183
331111000086	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111000087	Walker A motif; other site
331111000088	ATP binding site [chemical binding]; other site
331111000089	Walker B motif; other site
331111000090	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
331111000091	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
331111000092	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
331111000093	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
331111000094	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
331111000095	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
331111000096	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
331111000097	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
331111000098	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111000099	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
331111000100	Outer membrane efflux protein; Region: OEP; pfam02321
331111000101	IS2 repressor TnpA; Reviewed; Region: PRK09413
331111000102	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000103	IS2 transposase TnpB; Reviewed; Region: PRK09409
331111000104	HTH-like domain; Region: HTH_21; pfam13276
331111000105	Integrase core domain; Region: rve; pfam00665
331111000106	Integrase core domain; Region: rve_3; pfam13683
331111000107	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
331111000108	Transposase; Region: HTH_Tnp_1; cl17663
331111000109	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000110	Transposase; Region: HTH_Tnp_1; cl17663
331111000111	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000112	Integrase core domain; Region: rve; pfam00665
331111000113	Integrase core domain; Region: rve_3; pfam13683
331111000114	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
331111000115	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
331111000116	conjugal transfer protein TraD; Provisional; Region: PRK13700
331111000117	F sex factor protein N terminal; Region: TraD_N; pfam12615
331111000118	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
331111000119	Walker A motif; other site
331111000120	ATP binding site [chemical binding]; other site
331111000121	Walker B motif; other site
331111000122	conjugal transfer surface exclusion protein TraT; Provisional; Region: PRK13731
331111000123	Enterobacterial TraT complement resistance protein; Region: TraT; pfam05818
331111000124	conjugal transfer mating pair stabilization protein TraG; Provisional; Region: PRK13735
331111000125	conjugal transfer pilus assembly protein TraH; Provisional; Region: PRK13723
331111000126	Domain of unknown function (DUF3560); Region: DUF3560; pfam12083
331111000127	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
331111000128	Antirestriction protein; Region: Antirestrict; pfam03230
331111000129	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
331111000130	putative methylase; Provisional; Region: PRK13699
331111000131	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
331111000132	Protein of unknown function (DUF1281); Region: DUF1281; pfam06924
331111000133	Plasmid stability protein; Region: Plasmid_stab_B; pfam10784
331111000134	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
331111000135	Mg binding site [ion binding]; other site
331111000136	nucleotide binding site [chemical binding]; other site
331111000137	putative protofilament interface [polypeptide binding]; other site
331111000138	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
331111000139	Predicted transcriptional regulator [Transcription]; Region: COG3905
331111000140	Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968
331111000141	replication protein; Provisional; Region: PRK13750
331111000142	Hok/gef family; Region: HOK_GEF; pfam01848
331111000143	type-F conjugative transfer system pilin acetylase TraX; Region: TraX_Ftype; TIGR02755
331111000144	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
331111000145	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
331111000146	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
331111000147	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
331111000148	dimer interface [polypeptide binding]; other site
331111000149	ssDNA binding site [nucleotide binding]; other site
331111000150	tetramer (dimer of dimers) interface [polypeptide binding]; other site
331111000151	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
331111000152	Antirestriction protein; Region: Antirestrict; pfam03230
331111000153	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
331111000154	putative methylase; Provisional; Region: PRK13699
331111000155	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
331111000156	Protein of unknown function (DUF1281); Region: DUF1281; pfam06924
331111000157	Plasmid stability protein; Region: Plasmid_stab_B; pfam10784
331111000158	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
331111000159	Mg binding site [ion binding]; other site
331111000160	nucleotide binding site [chemical binding]; other site
331111000161	putative protofilament interface [polypeptide binding]; other site
331111000162	Phage integrase family; Region: Phage_integrase; pfam00589
331111000163	active site
331111000164	DNA binding site [nucleotide binding]
331111000165	Int/Topo IB signature motif; other site
331111000166	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
331111000167	oligomeric interface; other site
331111000168	putative active site [active]
331111000169	homodimer interface [polypeptide binding]; other site
331111000170	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111000171	Walker B; other site
331111000172	D-loop; other site
331111000173	H-loop/switch region; other site
331111000174	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
331111000175	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111000176	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
331111000177	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
331111000178	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111000179	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111000180	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111000181	Transposase; Region: HTH_Tnp_1; pfam01527
331111000182	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000183	natural product precursor, GG-Bacteroidales family; Region: GG_sam_targ_CFB; TIGR04149
331111000184	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
331111000185	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111000186	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
331111000187	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
331111000188	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
331111000189	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111000190	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
331111000191	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
331111000192	putative active site [active]
331111000193	putative nucleic acid binding site [nucleotide binding]; other site
331111000194	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
331111000195	IS2 repressor TnpA; Reviewed; Region: PRK09413
331111000196	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000197	IS2 transposase TnpB; Reviewed; Region: PRK09409
331111000198	HTH-like domain; Region: HTH_21; pfam13276
331111000199	Integrase core domain; Region: rve; pfam00665
331111000200	Integrase core domain; Region: rve_3; pfam13683
331111000201	CblD like pilus biogenesis initiator; Region: CblD; pfam07434
331111000202	fimbrial outer membrane usher protein TcfC; Provisional; Region: PRK15310
331111000203	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
331111000204	putative fimbrial protein TcfA; Provisional; Region: PRK15308
331111000205	transposase/IS protein; Provisional; Region: PRK09183
331111000206	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111000207	Walker A motif; other site
331111000208	ATP binding site [chemical binding]; other site
331111000209	Walker B motif; other site
331111000210	arginine finger; other site
331111000211	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
331111000212	Helix-turn-helix domain; Region: HTH_38; pfam13936
331111000213	Integrase core domain; Region: rve; pfam00665
331111000214	Integrase core domain; Region: rve_3; cl15866
331111000215	Plasmid stabilisation system protein; Region: Plasmid_stabil; cl17483
331111000216	Predicted transcriptional regulator [Transcription]; Region: COG3905
331111000217	IncFII RepA protein family; Region: IncFII_repA; cl11495
331111000218	N-Utilization Substance G (NusG) N-terminal (NGN) domain Superfamily; Region: NGN; cl02766
331111000219	Protein of unknown function (DUF2913); Region: DUF2913; pfam11140
331111000220	Toxin co-regulated pilus biosynthesis protein Q; Region: TcpQ; pfam10671
331111000221	PilM; Region: PilM; pfam07419
331111000222	Transposase; Region: HTH_Tnp_1; cl17663
331111000223	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000224	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
331111000225	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
331111000226	putative active site [active]
331111000227	putative NTP binding site [chemical binding]; other site
331111000228	putative nucleic acid binding site [nucleotide binding]; other site
331111000229	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
331111000230	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
331111000231	Methyltransferase domain; Region: Methyltransf_27; pfam13708
331111000232	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
331111000233	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
331111000234	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111000235	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
331111000236	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
331111000237	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111000238	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111000239	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111000240	Transposase; Region: HTH_Tnp_1; pfam01527
331111000241	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000242	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
331111000243	putative transposase; Provisional; Region: PRK09857
331111000244	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
331111000245	Protein of unknown function (DUF1472); Region: DUF1472; pfam07339
331111000246	Antirestriction protein (ArdA); Region: ArdA; pfam07275
331111000247	PsiA protein; Region: PsiA; cl11646
331111000248	plasmid SOS inhibition protein B; Provisional; Region: psiB; PRK13701
331111000249	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
331111000250	Aminoglycoside/hydroxyurea antibiotic resistance kinase; Region: APH_6_hur; pfam04655
331111000251	Aminoglycoside 3'-phosphotransferase (APH). The APH subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin...; Region: APH; cd05150
331111000252	Phosphotransferase enzyme family; Region: APH; pfam01636
331111000253	active site
331111000254	ATP binding site [chemical binding]; other site
331111000255	antibiotic binding site [chemical binding]; other site
331111000256	dihydropteroate synthase; Region: DHPS; TIGR01496
331111000257	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
331111000258	substrate binding pocket [chemical binding]; other site
331111000259	dimer interface [polypeptide binding]; other site
331111000260	inhibitor binding site; inhibition site
331111000261	Putative transposase; Region: Y2_Tnp; pfam04986
331111000262	Transposase; Region: HTH_Tnp_1; pfam01527
331111000263	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000264	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111000265	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111000266	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
331111000267	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
331111000268	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111000269	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
331111000270	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
331111000271	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111000272	IS2 repressor TnpA; Reviewed; Region: PRK09413
331111000273	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000274	IS2 transposase TnpB; Reviewed; Region: PRK09409
331111000275	Putative transposase; Region: Y2_Tnp; pfam04986
331111000276	plasmid SOS inhibition protein B; Provisional; Region: psiB; PRK13701
331111000277	plasmid SOS inhibition protein A; Provisional; Region: PRK13704
331111000278	Transposase; Region: HTH_Tnp_1; pfam01527
331111000279	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000280	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
331111000281	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
331111000282	putative active site [active]
331111000283	putative NTP binding site [chemical binding]; other site
331111000284	putative nucleic acid binding site [nucleotide binding]; other site
331111000285	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
331111000286	transposase/IS protein; Provisional; Region: PRK09183
331111000287	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111000288	Walker A motif; other site
331111000289	ATP binding site [chemical binding]; other site
331111000290	Walker B motif; other site
331111000291	arginine finger; other site
331111000292	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
331111000293	Helix-turn-helix domain; Region: HTH_38; pfam13936
331111000294	Integrase core domain; Region: rve; pfam00665
331111000295	Integrase core domain; Region: rve_3; cl15866
331111000296	Protein of unknown function (DUF1281); Region: DUF1281; pfam06924
331111000297	plasmid-partitioning protein; Provisional; Region: PRK13698
331111000298	ParB-like nuclease domain; Region: ParB; smart00470
331111000299	plasmid-partitioning protein SopA; Provisional; Region: PRK13705
331111000300	MerR family regulatory protein; Region: MerR; pfam00376
331111000301	DNA binding residues [nucleotide binding]
331111000302	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
331111000303	P-loop; other site
331111000304	Magnesium ion binding site [ion binding]; other site
331111000305	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
331111000306	Magnesium ion binding site [ion binding]; other site
331111000307	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
331111000308	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
331111000309	putative active site [active]
331111000310	putative NTP binding site [chemical binding]; other site
331111000311	putative nucleic acid binding site [nucleotide binding]; other site
331111000312	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
331111000313	Transposase; Region: HTH_Tnp_1; pfam01527
331111000314	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000315	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
331111000316	DNA methylase; Region: N6_N4_Mtase; cl17433
331111000317	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
331111000318	Domain of unknown function (DUF3560); Region: DUF3560; pfam12083
331111000319	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111000320	S-adenosylmethionine binding site [chemical binding]; other site
331111000321	Domain of unknown function (DUF932); Region: DUF932; pfam06067
331111000322	transposase/IS protein; Provisional; Region: PRK09183
331111000323	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111000324	Walker A motif; other site
331111000325	ATP binding site [chemical binding]; other site
331111000326	Walker B motif; other site
331111000327	arginine finger; other site
331111000328	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
331111000329	Helix-turn-helix domain; Region: HTH_38; pfam13936
331111000330	Integrase core domain; Region: rve; pfam00665
331111000331	Integrase core domain; Region: rve_3; cl15866
331111000332	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
331111000333	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
331111000334	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111000335	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
331111000336	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
331111000337	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111000338	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111000339	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111000340	Transposase; Region: HTH_Tnp_1; pfam01527
331111000341	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000342	IS2 repressor TnpA; Reviewed; Region: PRK09413
331111000343	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000344	IS2 transposase TnpB; Reviewed; Region: PRK09409
331111000345	HTH-like domain; Region: HTH_21; pfam13276
331111000346	Integrase core domain; Region: rve; pfam00665
331111000347	Integrase core domain; Region: rve_3; pfam13683
331111000348	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
331111000349	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
331111000350	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
331111000351	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
331111000352	Transposase; Region: HTH_Tnp_1; pfam01527
331111000353	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000354	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111000355	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111000356	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
331111000357	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
331111000358	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111000359	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
331111000360	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
331111000361	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111000362	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
331111000363	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
331111000364	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
331111000365	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
331111000366	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
331111000367	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
331111000368	Autotransporter beta-domain; Region: Autotransporter; pfam03797
331111000369	transcriptional regulator YdeO; Provisional; Region: PRK09940
331111000370	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111000371	EAL domain; Region: EAL; pfam00563
331111000372	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
331111000373	Serine recombinase (SR) family, Partitioning (par)-Resolvase subfamily, catalytic domain; Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient...; Region: SR_Res_par; cd03767
331111000374	catalytic residues [active]
331111000375	catalytic nucleophile [active]
331111000376	Phage integrase family; Region: Phage_integrase; pfam00589
331111000377	active site
331111000378	DNA binding site [nucleotide binding]
331111000379	Int/Topo IB signature motif; other site
331111000380	plasmid maintenance protein CcdB; Provisional; Region: PRK13708
331111000381	plasmid maintenance protein CcdA; Provisional; Region: PRK13710
331111000382	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
331111000383	putative active site [active]
331111000384	putative metal binding site [ion binding]; other site
331111000385	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
331111000386	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
331111000387	Protein of unknown function (DUF535); Region: DUF535; pfam04393
331111000388	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
331111000389	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111000390	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
331111000391	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
331111000392	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111000393	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111000394	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111000395	Transposase; Region: HTH_Tnp_1; pfam01527
331111000396	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111000397	TraA; Region: TraA; pfam05513
331111000398	conjugal transfer pilus assembly protein TraL; Provisional; Region: PRK13707
331111000399	conjugal transfer pilus assembly protein TraE; Provisional; Region: PRK13726
331111000400	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
331111000401	Type IV secretion-system coupling protein DNA-binding domain; Region: TrwB_AAD_bind; pfam10412
331111000402	Walker A motif; other site
331111000403	ATP binding site [chemical binding]; other site
331111000404	Walker B motif; other site
331111000405	DNA helicase TraI; Region: TraI; pfam07057
331111000406	TraX protein; Region: TraX; cl05434
331111000407	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
331111000408	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
331111000409	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
331111000410	putative catalytic residues [active]
331111000411	putative nucleotide binding site [chemical binding]; other site
331111000412	putative aspartate binding site [chemical binding]; other site
331111000413	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
331111000414	dimer interface [polypeptide binding]; other site
331111000415	putative threonine allosteric regulatory site; other site
331111000416	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
331111000417	putative threonine allosteric regulatory site; other site
331111000418	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
331111000419	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
331111000420	homoserine kinase; Region: thrB; TIGR00191
331111000421	Protein of unknown function; Region: YhfT; pfam10797
331111000422	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
331111000423	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
331111000424	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
331111000425	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111000426	catalytic residue [active]
331111000427	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
331111000428	Transposase; Region: DEDD_Tnp_IS110; pfam01548
331111000429	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
331111000430	hypothetical protein; Validated; Region: PRK02101
331111000431	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
331111000432	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
331111000433	transaldolase-like protein; Provisional; Region: PTZ00411
331111000434	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
331111000435	active site
331111000436	dimer interface [polypeptide binding]; other site
331111000437	catalytic residue [active]
331111000438	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
331111000439	MPT binding site; other site
331111000440	trimer interface [polypeptide binding]; other site
331111000441	hypothetical protein; Provisional; Region: PRK10659
331111000442	hypothetical protein; Provisional; Region: PRK10236
331111000443	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
331111000444	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
331111000445	hypothetical protein; Provisional; Region: PRK10154
331111000446	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
331111000447	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
331111000448	nucleotide binding site [chemical binding]; other site
331111000449	NEF interaction site [polypeptide binding]; other site
331111000450	SBD interface [polypeptide binding]; other site
331111000451	chaperone protein DnaJ; Provisional; Region: PRK10767
331111000452	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
331111000453	HSP70 interaction site [polypeptide binding]; other site
331111000454	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
331111000455	substrate binding site [polypeptide binding]; other site
331111000456	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
331111000457	Zn binding sites [ion binding]; other site
331111000458	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
331111000459	dimer interface [polypeptide binding]; other site
331111000460	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
331111000461	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
331111000462	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111000463	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
331111000464	putative dimerization interface [polypeptide binding]; other site
331111000465	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
331111000466	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
331111000467	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
331111000468	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
331111000469	active site
331111000470	Riboflavin kinase; Region: Flavokinase; smart00904
331111000471	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
331111000472	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
331111000473	HIGH motif; other site
331111000474	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
331111000475	active site
331111000476	KMSKS motif; other site
331111000477	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
331111000478	tRNA binding surface [nucleotide binding]; other site
331111000479	anticodon binding site; other site
331111000480	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
331111000481	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
331111000482	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
331111000483	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
331111000484	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
331111000485	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
331111000486	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
331111000487	active site
331111000488	tetramer interface [polypeptide binding]; other site
331111000489	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
331111000490	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
331111000491	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
331111000492	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
331111000493	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
331111000494	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
331111000495	catalytic site [active]
331111000496	subunit interface [polypeptide binding]; other site
331111000497	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
331111000498	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
331111000499	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
331111000500	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
331111000501	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
331111000502	ATP-grasp domain; Region: ATP-grasp_4; cl17255
331111000503	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
331111000504	IMP binding site; other site
331111000505	dimer interface [polypeptide binding]; other site
331111000506	interdomain contacts; other site
331111000507	partial ornithine binding site; other site
331111000508	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
331111000509	carnitine operon protein CaiE; Provisional; Region: PRK13627
331111000510	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
331111000511	putative trimer interface [polypeptide binding]; other site
331111000512	putative metal binding site [ion binding]; other site
331111000513	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
331111000514	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
331111000515	substrate binding site [chemical binding]; other site
331111000516	oxyanion hole (OAH) forming residues; other site
331111000517	trimer interface [polypeptide binding]; other site
331111000518	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
331111000519	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
331111000520	acyl-activating enzyme (AAE) consensus motif; other site
331111000521	putative AMP binding site [chemical binding]; other site
331111000522	putative active site [active]
331111000523	putative CoA binding site [chemical binding]; other site
331111000524	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
331111000525	CoA-transferase family III; Region: CoA_transf_3; pfam02515
331111000526	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
331111000527	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
331111000528	active site
331111000529	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
331111000530	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
331111000531	Ligand binding site [chemical binding]; other site
331111000532	Electron transfer flavoprotein domain; Region: ETF; pfam01012
331111000533	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
331111000534	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF; cd01985
331111000535	Ligand binding site [chemical binding]; other site
331111000536	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
331111000537	putative oxidoreductase FixC; Provisional; Region: PRK10157
331111000538	ferredoxin-like protein FixX; Provisional; Region: PRK15449
331111000539	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111000540	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
331111000541	putative substrate translocation pore; other site
331111000542	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
331111000543	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
331111000544	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
331111000545	TrkA-N domain; Region: TrkA_N; pfam02254
331111000546	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
331111000547	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
331111000548	folate binding site [chemical binding]; other site
331111000549	NADP+ binding site [chemical binding]; other site
331111000550	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
331111000551	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
331111000552	active site
331111000553	metal binding site [ion binding]; metal-binding site
331111000554	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
331111000555	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
331111000556	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
331111000557	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
331111000558	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
331111000559	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
331111000560	SurA N-terminal domain; Region: SurA_N; pfam09312
331111000561	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
331111000562	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
331111000563	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
331111000564	OstA-like protein; Region: OstA; pfam03968
331111000565	Organic solvent tolerance protein; Region: OstA_C; pfam04453
331111000566	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
331111000567	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
331111000568	putative metal binding site [ion binding]; other site
331111000569	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
331111000570	HSP70 interaction site [polypeptide binding]; other site
331111000571	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
331111000572	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
331111000573	active site
331111000574	ATP-dependent helicase HepA; Validated; Region: PRK04914
331111000575	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
331111000576	ATP binding site [chemical binding]; other site
331111000577	putative Mg++ binding site [ion binding]; other site
331111000578	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111000579	nucleotide binding region [chemical binding]; other site
331111000580	ATP-binding site [chemical binding]; other site
331111000581	DNA polymerase II; Reviewed; Region: PRK05762
331111000582	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
331111000583	active site
331111000584	catalytic site [active]
331111000585	substrate binding site [chemical binding]; other site
331111000586	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
331111000587	active site
331111000588	metal-binding site
331111000589	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
331111000590	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
331111000591	intersubunit interface [polypeptide binding]; other site
331111000592	active site
331111000593	Zn2+ binding site [ion binding]; other site
331111000594	L-arabinose isomerase; Provisional; Region: PRK02929
331111000595	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
331111000596	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
331111000597	trimer interface [polypeptide binding]; other site
331111000598	putative substrate binding site [chemical binding]; other site
331111000599	putative metal binding site [ion binding]; other site
331111000600	ribulokinase; Provisional; Region: PRK04123
331111000601	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
331111000602	N- and C-terminal domain interface [polypeptide binding]; other site
331111000603	active site
331111000604	MgATP binding site [chemical binding]; other site
331111000605	catalytic site [active]
331111000606	metal binding site [ion binding]; metal-binding site
331111000607	carbohydrate binding site [chemical binding]; other site
331111000608	homodimer interface [polypeptide binding]; other site
331111000609	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
331111000610	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
331111000611	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111000612	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111000613	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
331111000614	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
331111000615	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
331111000616	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
331111000617	Walker A/P-loop; other site
331111000618	ATP binding site [chemical binding]; other site
331111000619	Q-loop/lid; other site
331111000620	ABC transporter signature motif; other site
331111000621	Walker B; other site
331111000622	D-loop; other site
331111000623	H-loop/switch region; other site
331111000624	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
331111000625	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111000626	dimer interface [polypeptide binding]; other site
331111000627	conserved gate region; other site
331111000628	putative PBP binding loops; other site
331111000629	ABC-ATPase subunit interface; other site
331111000630	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111000631	dimer interface [polypeptide binding]; other site
331111000632	conserved gate region; other site
331111000633	putative PBP binding loops; other site
331111000634	ABC-ATPase subunit interface; other site
331111000635	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
331111000636	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
331111000637	transcriptional regulator SgrR; Provisional; Region: PRK13626
331111000638	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
331111000639	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
331111000640	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111000641	sugar efflux transporter; Region: 2A0120; TIGR00899
331111000642	putative substrate translocation pore; other site
331111000643	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
331111000644	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
331111000645	substrate binding site [chemical binding]; other site
331111000646	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
331111000647	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
331111000648	substrate binding site [chemical binding]; other site
331111000649	ligand binding site [chemical binding]; other site
331111000650	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
331111000651	tartrate dehydrogenase; Region: TTC; TIGR02089
331111000652	2-isopropylmalate synthase; Validated; Region: PRK00915
331111000653	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
331111000654	active site
331111000655	catalytic residues [active]
331111000656	metal binding site [ion binding]; metal-binding site
331111000657	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
331111000658	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
331111000659	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111000660	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
331111000661	putative substrate binding pocket [chemical binding]; other site
331111000662	putative dimerization interface [polypeptide binding]; other site
331111000663	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
331111000664	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
331111000665	PYR/PP interface [polypeptide binding]; other site
331111000666	dimer interface [polypeptide binding]; other site
331111000667	TPP binding site [chemical binding]; other site
331111000668	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
331111000669	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
331111000670	TPP-binding site [chemical binding]; other site
331111000671	dimer interface [polypeptide binding]; other site
331111000672	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
331111000673	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
331111000674	putative valine binding site [chemical binding]; other site
331111000675	dimer interface [polypeptide binding]; other site
331111000676	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
331111000677	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
331111000678	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
331111000679	DNA binding site [nucleotide binding]
331111000680	domain linker motif; other site
331111000681	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
331111000682	dimerization interface [polypeptide binding]; other site
331111000683	ligand binding site [chemical binding]; other site
331111000684	mraZ protein; Region: TIGR00242
331111000685	MraZ protein; Region: MraZ; pfam02381
331111000686	MraZ protein; Region: MraZ; pfam02381
331111000687	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
331111000688	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
331111000689	cell division protein FtsL; Provisional; Region: PRK10772
331111000690	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
331111000691	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
331111000692	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
331111000693	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
331111000694	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
331111000695	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
331111000696	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
331111000697	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
331111000698	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
331111000699	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
331111000700	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
331111000701	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
331111000702	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
331111000703	Mg++ binding site [ion binding]; other site
331111000704	putative catalytic motif [active]
331111000705	putative substrate binding site [chemical binding]; other site
331111000706	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
331111000707	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
331111000708	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
331111000709	cell division protein FtsW; Provisional; Region: PRK10774
331111000710	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
331111000711	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
331111000712	active site
331111000713	homodimer interface [polypeptide binding]; other site
331111000714	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
331111000715	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
331111000716	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
331111000717	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
331111000718	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
331111000719	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
331111000720	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
331111000721	cell division protein FtsQ; Provisional; Region: PRK10775
331111000722	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
331111000723	Cell division protein FtsQ; Region: FtsQ; pfam03799
331111000724	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
331111000725	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
331111000726	Cell division protein FtsA; Region: FtsA; pfam14450
331111000727	cell division protein FtsZ; Validated; Region: PRK09330
331111000728	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
331111000729	nucleotide binding site [chemical binding]; other site
331111000730	SulA interaction site; other site
331111000731	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
331111000732	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
331111000733	SecA regulator SecM; Provisional; Region: PRK02943
331111000734	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
331111000735	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
331111000736	SEC-C motif; Region: SEC-C; pfam02810
331111000737	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
331111000738	active site
331111000739	8-oxo-dGMP binding site [chemical binding]; other site
331111000740	nudix motif; other site
331111000741	metal binding site [ion binding]; metal-binding site
331111000742	DNA gyrase inhibitor; Reviewed; Region: PRK00418
331111000743	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
331111000744	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
331111000745	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
331111000746	CoA-binding site [chemical binding]; other site
331111000747	ATP-binding [chemical binding]; other site
331111000748	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
331111000749	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
331111000750	active site
331111000751	hypothetical protein; Provisional; Region: PRK10436
331111000752	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
331111000753	Walker A motif; other site
331111000754	ATP binding site [chemical binding]; other site
331111000755	Walker B motif; other site
331111000756	putative major pilin subunit; Provisional; Region: PRK10574
331111000757	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
331111000758	Pilin (bacterial filament); Region: Pilin; pfam00114
331111000759	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
331111000760	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
331111000761	dimerization interface [polypeptide binding]; other site
331111000762	active site
331111000763	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
331111000764	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
331111000765	amidase catalytic site [active]
331111000766	Zn binding residues [ion binding]; other site
331111000767	substrate binding site [chemical binding]; other site
331111000768	regulatory protein AmpE; Provisional; Region: PRK10987
331111000769	aromatic amino acid transporter; Provisional; Region: PRK10238
331111000770	Transcriptional regulators [Transcription]; Region: FadR; COG2186
331111000771	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111000772	DNA-binding site [nucleotide binding]; DNA binding site
331111000773	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
331111000774	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
331111000775	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
331111000776	dimer interface [polypeptide binding]; other site
331111000777	TPP-binding site [chemical binding]; other site
331111000778	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
331111000779	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
331111000780	E3 interaction surface; other site
331111000781	lipoyl attachment site [posttranslational modification]; other site
331111000782	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
331111000783	E3 interaction surface; other site
331111000784	lipoyl attachment site [posttranslational modification]; other site
331111000785	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
331111000786	E3 interaction surface; other site
331111000787	lipoyl attachment site [posttranslational modification]; other site
331111000788	e3 binding domain; Region: E3_binding; pfam02817
331111000789	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
331111000790	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
331111000791	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
331111000792	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111000793	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
331111000794	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
331111000795	Protein of unknown function (DUF3106); Region: DUF3106; pfam11304
331111000796	Protein of unknown function (DUF3106); Region: DUF3106; pfam11304
331111000797	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
331111000798	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
331111000799	substrate binding site [chemical binding]; other site
331111000800	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
331111000801	substrate binding site [chemical binding]; other site
331111000802	ligand binding site [chemical binding]; other site
331111000803	hypothetical protein; Provisional; Region: PRK05248
331111000804	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
331111000805	spermidine synthase; Provisional; Region: PRK00811
331111000806	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111000807	S-adenosylmethionine binding site [chemical binding]; other site
331111000808	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
331111000809	multicopper oxidase; Provisional; Region: PRK10965
331111000810	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
331111000811	Multicopper oxidase; Region: Cu-oxidase; pfam00394
331111000812	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
331111000813	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
331111000814	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
331111000815	Trp docking motif [polypeptide binding]; other site
331111000816	putative active site [active]
331111000817	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
331111000818	active site
331111000819	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
331111000820	active site clefts [active]
331111000821	zinc binding site [ion binding]; other site
331111000822	dimer interface [polypeptide binding]; other site
331111000823	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
331111000824	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
331111000825	Walker A/P-loop; other site
331111000826	ATP binding site [chemical binding]; other site
331111000827	Q-loop/lid; other site
331111000828	ABC transporter signature motif; other site
331111000829	Walker B; other site
331111000830	D-loop; other site
331111000831	H-loop/switch region; other site
331111000832	inner membrane transport permease; Provisional; Region: PRK15066
331111000833	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
331111000834	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
331111000835	active pocket/dimerization site; other site
331111000836	active site
331111000837	phosphorylation site [posttranslational modification]
331111000838	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
331111000839	putative active site [active]
331111000840	putative metal binding site [ion binding]; other site
331111000841	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
331111000842	tetramerization interface [polypeptide binding]; other site
331111000843	active site
331111000844	Uncharacterized conserved protein [Function unknown]; Region: COG5464
331111000845	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
331111000846	pantoate--beta-alanine ligase; Region: panC; TIGR00018
331111000847	Pantoate-beta-alanine ligase; Region: PanC; cd00560
331111000848	active site
331111000849	ATP-binding site [chemical binding]; other site
331111000850	pantoate-binding site; other site
331111000851	HXXH motif; other site
331111000852	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
331111000853	oligomerization interface [polypeptide binding]; other site
331111000854	active site
331111000855	metal binding site [ion binding]; metal-binding site
331111000856	putative fimbrial-like adhesin protein; Provisional; Region: PRK09723
331111000857	putative fimbrial protein StaF; Provisional; Region: PRK15262
331111000858	putative fimbrial protein StaE; Provisional; Region: PRK15263
331111000859	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
331111000860	PapC N-terminal domain; Region: PapC_N; pfam13954
331111000861	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
331111000862	PapC C-terminal domain; Region: PapC_C; pfam13953
331111000863	putative chaperone protein EcpD; Provisional; Region: PRK09926
331111000864	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
331111000865	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
331111000866	Fimbrial protein; Region: Fimbrial; cl01416
331111000867	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
331111000868	catalytic center binding site [active]
331111000869	ATP binding site [chemical binding]; other site
331111000870	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
331111000871	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
331111000872	active site
331111000873	NTP binding site [chemical binding]; other site
331111000874	metal binding triad [ion binding]; metal-binding site
331111000875	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
331111000876	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
331111000877	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
331111000878	tRNA synthetases class I (E and Q), catalytic domain; Region: tRNA-synt_1c; pfam00749
331111000879	active site
331111000880	nucleotide binding site [chemical binding]; other site
331111000881	HIGH motif; other site
331111000882	KMSKS motif; other site
331111000883	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
331111000884	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
331111000885	2'-5' RNA ligase; Provisional; Region: PRK15124
331111000886	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
331111000887	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
331111000888	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
331111000889	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
331111000890	ATP binding site [chemical binding]; other site
331111000891	putative Mg++ binding site [ion binding]; other site
331111000892	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111000893	nucleotide binding region [chemical binding]; other site
331111000894	ATP-binding site [chemical binding]; other site
331111000895	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
331111000896	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
331111000897	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
331111000898	Transglycosylase; Region: Transgly; pfam00912
331111000899	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
331111000900	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
331111000901	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
331111000902	N-terminal plug; other site
331111000903	ligand-binding site [chemical binding]; other site
331111000904	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
331111000905	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
331111000906	Walker A/P-loop; other site
331111000907	ATP binding site [chemical binding]; other site
331111000908	Q-loop/lid; other site
331111000909	ABC transporter signature motif; other site
331111000910	Walker B; other site
331111000911	D-loop; other site
331111000912	H-loop/switch region; other site
331111000913	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
331111000914	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
331111000915	siderophore binding site; other site
331111000916	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
331111000917	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
331111000918	ABC-ATPase subunit  interface; other site
331111000919	dimer interface [polypeptide binding]; other site
331111000920	putative PBP binding regions; other site
331111000921	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
331111000922	ABC-ATPase subunit  interface; other site
331111000923	dimer interface [polypeptide binding]; other site
331111000924	putative PBP binding regions; other site
331111000925	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
331111000926	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
331111000927	inhibitor-cofactor binding pocket; inhibition site
331111000928	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111000929	catalytic residue [active]
331111000930	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
331111000931	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
331111000932	Cl- selectivity filter; other site
331111000933	Cl- binding residues [ion binding]; other site
331111000934	pore gating glutamate residue; other site
331111000935	dimer interface [polypeptide binding]; other site
331111000936	H+/Cl- coupling transport residue; other site
331111000937	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
331111000938	hypothetical protein; Provisional; Region: PRK10578
331111000939	UPF0126 domain; Region: UPF0126; pfam03458
331111000940	UPF0126 domain; Region: UPF0126; pfam03458
331111000941	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
331111000942	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
331111000943	cobalamin binding residues [chemical binding]; other site
331111000944	putative BtuC binding residues; other site
331111000945	dimer interface [polypeptide binding]; other site
331111000946	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
331111000947	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
331111000948	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
331111000949	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
331111000950	Zn2+ binding site [ion binding]; other site
331111000951	Mg2+ binding site [ion binding]; other site
331111000952	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
331111000953	serine endoprotease; Provisional; Region: PRK10942
331111000954	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
331111000955	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
331111000956	protein binding site [polypeptide binding]; other site
331111000957	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
331111000958	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
331111000959	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
331111000960	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
331111000961	hypothetical protein; Provisional; Region: PRK13677
331111000962	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
331111000963	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
331111000964	trimer interface [polypeptide binding]; other site
331111000965	active site
331111000966	substrate binding site [chemical binding]; other site
331111000967	CoA binding site [chemical binding]; other site
331111000968	PII uridylyl-transferase; Provisional; Region: PRK05007
331111000969	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
331111000970	metal binding triad; other site
331111000971	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
331111000972	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
331111000973	Zn2+ binding site [ion binding]; other site
331111000974	Mg2+ binding site [ion binding]; other site
331111000975	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
331111000976	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
331111000977	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
331111000978	active site
331111000979	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
331111000980	rRNA interaction site [nucleotide binding]; other site
331111000981	S8 interaction site; other site
331111000982	putative laminin-1 binding site; other site
331111000983	elongation factor Ts; Provisional; Region: tsf; PRK09377
331111000984	UBA/TS-N domain; Region: UBA; pfam00627
331111000985	Elongation factor TS; Region: EF_TS; pfam00889
331111000986	Elongation factor TS; Region: EF_TS; pfam00889
331111000987	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
331111000988	putative nucleotide binding site [chemical binding]; other site
331111000989	uridine monophosphate binding site [chemical binding]; other site
331111000990	homohexameric interface [polypeptide binding]; other site
331111000991	ribosome recycling factor; Reviewed; Region: frr; PRK00083
331111000992	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
331111000993	hinge region; other site
331111000994	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
331111000995	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
331111000996	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
331111000997	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
331111000998	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
331111000999	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
331111001000	catalytic residue [active]
331111001001	putative FPP diphosphate  binding site; other site
331111001002	putative FPP binding hydrophobic cleft; other site
331111001003	dimer interface [polypeptide binding]; other site
331111001004	putative IPP diphosphate binding site; other site
331111001005	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
331111001006	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
331111001007	zinc metallopeptidase RseP; Provisional; Region: PRK10779
331111001008	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
331111001009	active site
331111001010	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
331111001011	protein binding site [polypeptide binding]; other site
331111001012	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
331111001013	putative substrate binding region [chemical binding]; other site
331111001014	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
331111001015	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
331111001016	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
331111001017	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
331111001018	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
331111001019	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
331111001020	Surface antigen; Region: Bac_surface_Ag; pfam01103
331111001021	periplasmic chaperone; Provisional; Region: PRK10780
331111001022	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
331111001023	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
331111001024	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
331111001025	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
331111001026	trimer interface [polypeptide binding]; other site
331111001027	active site
331111001028	UDP-GlcNAc binding site [chemical binding]; other site
331111001029	lipid binding site [chemical binding]; lipid-binding site
331111001030	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
331111001031	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
331111001032	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
331111001033	active site
331111001034	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
331111001035	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
331111001036	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
331111001037	RNA/DNA hybrid binding site [nucleotide binding]; other site
331111001038	active site
331111001039	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
331111001040	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
331111001041	putative active site [active]
331111001042	putative PHP Thumb interface [polypeptide binding]; other site
331111001043	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
331111001044	generic binding surface II; other site
331111001045	generic binding surface I; other site
331111001046	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
331111001047	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
331111001048	lysine decarboxylase LdcC; Provisional; Region: PRK15399
331111001049	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
331111001050	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
331111001051	homodimer interface [polypeptide binding]; other site
331111001052	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111001053	catalytic residue [active]
331111001054	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
331111001055	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
331111001056	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
331111001057	putative metal binding site [ion binding]; other site
331111001058	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
331111001059	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
331111001060	Ligand Binding Site [chemical binding]; other site
331111001061	TilS substrate binding domain; Region: TilS; pfam09179
331111001062	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
331111001063	Rho-binding antiterminator; Provisional; Region: PRK11625
331111001064	hypothetical protein; Provisional; Region: PRK04964
331111001065	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
331111001066	hypothetical protein; Provisional; Region: PRK09256
331111001067	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
331111001068	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
331111001069	NlpE N-terminal domain; Region: NlpE; pfam04170
331111001070	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
331111001071	Transposase; Region: DEDD_Tnp_IS110; pfam01548
331111001072	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
331111001073	prolyl-tRNA synthetase; Provisional; Region: PRK09194
331111001074	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
331111001075	dimer interface [polypeptide binding]; other site
331111001076	motif 1; other site
331111001077	active site
331111001078	motif 2; other site
331111001079	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
331111001080	putative deacylase active site [active]
331111001081	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
331111001082	active site
331111001083	motif 3; other site
331111001084	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
331111001085	anticodon binding site; other site
331111001086	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
331111001087	homodimer interaction site [polypeptide binding]; other site
331111001088	cofactor binding site; other site
331111001089	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
331111001090	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
331111001091	lipoprotein, YaeC family; Region: TIGR00363
331111001092	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111001093	dimer interface [polypeptide binding]; other site
331111001094	conserved gate region; other site
331111001095	ABC-ATPase subunit interface; other site
331111001096	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
331111001097	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
331111001098	Walker A/P-loop; other site
331111001099	ATP binding site [chemical binding]; other site
331111001100	Q-loop/lid; other site
331111001101	ABC transporter signature motif; other site
331111001102	Walker B; other site
331111001103	D-loop; other site
331111001104	H-loop/switch region; other site
331111001105	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
331111001106	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
331111001107	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111001108	active site
331111001109	motif I; other site
331111001110	motif II; other site
331111001111	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
331111001112	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
331111001113	active site
331111001114	catalytic tetrad [active]
331111001115	Transcriptional regulator [Transcription]; Region: LysR; COG0583
331111001116	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111001117	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
331111001118	putative effector binding pocket; other site
331111001119	dimerization interface [polypeptide binding]; other site
331111001120	hypothetical protein; Provisional; Region: PRK05421
331111001121	putative catalytic site [active]
331111001122	putative metal binding site [ion binding]; other site
331111001123	putative phosphate binding site [ion binding]; other site
331111001124	putative catalytic site [active]
331111001125	putative phosphate binding site [ion binding]; other site
331111001126	putative metal binding site [ion binding]; other site
331111001127	Methyltransferase domain; Region: Methyltransf_31; pfam13847
331111001128	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111001129	S-adenosylmethionine binding site [chemical binding]; other site
331111001130	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
331111001131	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
331111001132	N-acetyl-D-glucosamine binding site [chemical binding]; other site
331111001133	catalytic residue [active]
331111001134	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
331111001135	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
331111001136	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
331111001137	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111001138	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
331111001139	RNA/DNA hybrid binding site [nucleotide binding]; other site
331111001140	active site
331111001141	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
331111001142	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
331111001143	active site
331111001144	catalytic site [active]
331111001145	substrate binding site [chemical binding]; other site
331111001146	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
331111001147	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
331111001148	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
331111001149	ImpA domain protein; Region: DUF3702; pfam12486
331111001150	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
331111001151	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
331111001152	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
331111001153	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
331111001154	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
331111001155	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
331111001156	type VI secretion-associated protein, VC_A0118 family; Region: VI_minor_1; TIGR03360
331111001157	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
331111001158	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111001159	Walker A motif; other site
331111001160	ATP binding site [chemical binding]; other site
331111001161	Walker B motif; other site
331111001162	arginine finger; other site
331111001163	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111001164	Walker A motif; other site
331111001165	ATP binding site [chemical binding]; other site
331111001166	Walker B motif; other site
331111001167	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
331111001168	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
331111001169	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
331111001170	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
331111001171	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
331111001172	Predicted component of the type VI protein secretion system, contains a FHA domain [Intracellular trafficking, secretion, and vesicular    transport; Signal transduction mechanisms]; Region: COG3456
331111001173	FHA domain; Region: FHA; pfam00498
331111001174	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
331111001175	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
331111001176	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
331111001177	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
331111001178	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
331111001179	Protein of unknown function (DUF877); Region: DUF877; pfam05943
331111001180	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
331111001181	Protein of unknown function (DUF770); Region: DUF770; pfam05591
331111001182	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
331111001183	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
331111001184	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
331111001185	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
331111001186	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
331111001187	PAAR motif; Region: PAAR_motif; cl15808
331111001188	RHS Repeat; Region: RHS_repeat; pfam05593
331111001189	RHS Repeat; Region: RHS_repeat; pfam05593
331111001190	RHS Repeat; Region: RHS_repeat; pfam05593
331111001191	RHS Repeat; Region: RHS_repeat; cl11982
331111001192	RHS Repeat; Region: RHS_repeat; cl11982
331111001193	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
331111001194	RHS Repeat; Region: RHS_repeat; pfam05593
331111001195	RHS Repeat; Region: RHS_repeat; cl11982
331111001196	RHS Repeat; Region: RHS_repeat; pfam05593
331111001197	RHS protein; Region: RHS; pfam03527
331111001198	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
331111001199	C-N hydrolase family amidase; Provisional; Region: PRK10438
331111001200	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
331111001201	putative active site [active]
331111001202	catalytic triad [active]
331111001203	dimer interface [polypeptide binding]; other site
331111001204	multimer interface [polypeptide binding]; other site
331111001205	C-lysozyme inhibitor; Provisional; Region: PRK09993
331111001206	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
331111001207	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
331111001208	active site
331111001209	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
331111001210	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
331111001211	dimer interface [polypeptide binding]; other site
331111001212	active site
331111001213	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
331111001214	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
331111001215	putative active site [active]
331111001216	putative dimer interface [polypeptide binding]; other site
331111001217	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
331111001218	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
331111001219	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
331111001220	RelB antitoxin; Region: RelB; cl01171
331111001221	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
331111001222	NlpC/P60 family; Region: NLPC_P60; pfam00877
331111001223	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
331111001224	HicB family; Region: HicB; pfam05534
331111001225	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; COG1298
331111001226	FHIPEP family; Region: FHIPEP; pfam00771
331111001227	hypothetical protein; Validated; Region: PRK06778
331111001228	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
331111001229	ligand binding site [chemical binding]; other site
331111001230	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
331111001231	active site
331111001232	DNA polymerase IV; Validated; Region: PRK02406
331111001233	DNA binding site [nucleotide binding]
331111001234	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
331111001235	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
331111001236	Coenzyme A binding pocket [chemical binding]; other site
331111001237	hypothetical protein; Reviewed; Region: PRK09588
331111001238	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
331111001239	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
331111001240	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
331111001241	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
331111001242	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
331111001243	metal binding site [ion binding]; metal-binding site
331111001244	dimer interface [polypeptide binding]; other site
331111001245	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
331111001246	active site
331111001247	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
331111001248	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
331111001249	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
331111001250	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
331111001251	trimer interface [polypeptide binding]; other site
331111001252	eyelet of channel; other site
331111001253	gamma-glutamyl kinase; Provisional; Region: PRK05429
331111001254	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
331111001255	nucleotide binding site [chemical binding]; other site
331111001256	homotetrameric interface [polypeptide binding]; other site
331111001257	putative phosphate binding site [ion binding]; other site
331111001258	putative allosteric binding site; other site
331111001259	PUA domain; Region: PUA; pfam01472
331111001260	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
331111001261	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
331111001262	putative catalytic cysteine [active]
331111001263	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
331111001264	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
331111001265	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
331111001266	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
331111001267	ATP binding site [chemical binding]; other site
331111001268	putative Mg++ binding site [ion binding]; other site
331111001269	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111001270	nucleotide binding region [chemical binding]; other site
331111001271	ATP-binding site [chemical binding]; other site
331111001272	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
331111001273	ligand binding site [chemical binding]; other site
331111001274	HsdM N-terminal domain; Region: HsdM_N; pfam12161
331111001275	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
331111001276	Methyltransferase domain; Region: Methyltransf_26; pfam13659
331111001277	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
331111001278	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
331111001279	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
331111001280	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_4; pfam14281
331111001281	Domain of unknown function (DUF4268); Region: DUF4268; pfam14088
331111001282	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
331111001283	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
331111001284	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
331111001285	ATP binding site [chemical binding]; other site
331111001286	putative Mg++ binding site [ion binding]; other site
331111001287	Domain of unknown function (DUF3387); Region: DUF3387; pfam11867
331111001288	Part of AAA domain; Region: AAA_19; pfam13245
331111001289	Family description; Region: UvrD_C_2; pfam13538
331111001290	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
331111001291	active site
331111001292	Int/Topo IB signature motif; other site
331111001293	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
331111001294	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
331111001295	XdhC Rossmann domain; Region: XdhC_C; pfam13478
331111001296	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
331111001297	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
331111001298	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
331111001299	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
331111001300	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
331111001301	aldehyde oxidoreductase 2Fe-2S subunit; Provisional; Region: PRK11433
331111001302	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
331111001303	catalytic loop [active]
331111001304	iron binding site [ion binding]; other site
331111001305	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
331111001306	Predicted periplasmic/secreted protein [Function unknown]; Region: COG3477
331111001307	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
331111001308	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
331111001309	putative fimbrial protein TcfA; Provisional; Region: PRK15308
331111001310	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
331111001311	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111001312	DNA binding residues [nucleotide binding]
331111001313	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
331111001314	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
331111001315	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
331111001316	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
331111001317	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
331111001318	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
331111001319	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
331111001320	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
331111001321	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111001322	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
331111001323	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
331111001324	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
331111001325	active site
331111001326	catalytic tetrad [active]
331111001327	Predicted membrane protein [Function unknown]; Region: COG3059
331111001328	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
331111001329	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
331111001330	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
331111001331	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111001332	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
331111001333	Cupin; Region: Cupin_6; pfam12852
331111001334	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
331111001335	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111001336	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
331111001337	Cysteine-rich domain; Region: CCG; pfam02754
331111001338	Cysteine-rich domain; Region: CCG; pfam02754
331111001339	iron-sulfur cluster-binding protein; Region: TIGR00273
331111001340	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
331111001341	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
331111001342	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
331111001343	Uncharacterized conserved protein [Function unknown]; Region: COG1556
331111001344	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
331111001345	choline dehydrogenase; Validated; Region: PRK02106
331111001346	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
331111001347	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
331111001348	NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090
331111001349	tetrameric interface [polypeptide binding]; other site
331111001350	NAD binding site [chemical binding]; other site
331111001351	catalytic residues [active]
331111001352	transcriptional regulator BetI; Validated; Region: PRK00767
331111001353	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
331111001354	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
331111001355	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
331111001356	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
331111001357	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
331111001358	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
331111001359	choline transport protein BetT; Provisional; Region: PRK09928
331111001360	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
331111001361	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
331111001362	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
331111001363	Autotransporter beta-domain; Region: Autotransporter; pfam03797
331111001364	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111001365	DNA binding residues [nucleotide binding]
331111001366	dimerization interface [polypeptide binding]; other site
331111001367	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
331111001368	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
331111001369	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111001370	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
331111001371	dimerization interface [polypeptide binding]; other site
331111001372	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
331111001373	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
331111001374	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
331111001375	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
331111001376	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
331111001377	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
331111001378	CoA binding domain; Region: CoA_binding; pfam02629
331111001379	CoA-ligase; Region: Ligase_CoA; pfam00549
331111001380	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
331111001381	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
331111001382	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
331111001383	putative substrate binding site [chemical binding]; other site
331111001384	nucleotide binding site [chemical binding]; other site
331111001385	nucleotide binding site [chemical binding]; other site
331111001386	homodimer interface [polypeptide binding]; other site
331111001387	putative deaminase; Validated; Region: PRK06846
331111001388	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
331111001389	active site
331111001390	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
331111001391	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
331111001392	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
331111001393	ligand binding site [chemical binding]; other site
331111001394	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
331111001395	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
331111001396	Walker A/P-loop; other site
331111001397	ATP binding site [chemical binding]; other site
331111001398	Q-loop/lid; other site
331111001399	ABC transporter signature motif; other site
331111001400	Walker B; other site
331111001401	D-loop; other site
331111001402	H-loop/switch region; other site
331111001403	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
331111001404	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
331111001405	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
331111001406	TM-ABC transporter signature motif; other site
331111001407	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
331111001408	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
331111001409	TM-ABC transporter signature motif; other site
331111001410	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
331111001411	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
331111001412	putative NAD(P) binding site [chemical binding]; other site
331111001413	putative substrate binding site [chemical binding]; other site
331111001414	catalytic Zn binding site [ion binding]; other site
331111001415	structural Zn binding site [ion binding]; other site
331111001416	dimer interface [polypeptide binding]; other site
331111001417	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
331111001418	hypothetical protein; Provisional; Region: PRK09929
331111001419	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
331111001420	Propionate catabolism activator; Region: PrpR_N; pfam06506
331111001421	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111001422	Walker A motif; other site
331111001423	ATP binding site [chemical binding]; other site
331111001424	Walker B motif; other site
331111001425	arginine finger; other site
331111001426	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
331111001427	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
331111001428	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
331111001429	tetramer interface [polypeptide binding]; other site
331111001430	active site
331111001431	Mg2+/Mn2+ binding site [ion binding]; other site
331111001432	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
331111001433	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
331111001434	dimer interface [polypeptide binding]; other site
331111001435	active site
331111001436	citrylCoA binding site [chemical binding]; other site
331111001437	oxalacetate/citrate binding site [chemical binding]; other site
331111001438	coenzyme A binding site [chemical binding]; other site
331111001439	catalytic triad [active]
331111001440	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
331111001441	2-methylcitrate dehydratase; Region: prpD; TIGR02330
331111001442	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
331111001443	Propionyl-CoA synthetase (PrpE); Region: PrpE; cd05967
331111001444	acyl-activating enzyme (AAE) consensus motif; other site
331111001445	putative AMP binding site [chemical binding]; other site
331111001446	putative active site [active]
331111001447	putative CoA binding site [chemical binding]; other site
331111001448	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
331111001449	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
331111001450	Na binding site [ion binding]; other site
331111001451	putative substrate binding site [chemical binding]; other site
331111001452	cytosine deaminase; Provisional; Region: PRK09230
331111001453	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
331111001454	active site
331111001455	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
331111001456	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111001457	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator CynR, contains the type 2 periplasmic binding fold; Region: PBP2_CynR; cd08425
331111001458	dimerization interface [polypeptide binding]; other site
331111001459	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
331111001460	active site clefts [active]
331111001461	zinc binding site [ion binding]; other site
331111001462	dimer interface [polypeptide binding]; other site
331111001463	Cyanate lyase [Inorganic ion transport and metabolism]; Region: CynS; COG1513
331111001464	Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate.  It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the...; Region: Cyanase_C; cd00559
331111001465	oligomer interface [polypeptide binding]; other site
331111001466	active site
331111001467	putative cyanate transporter; Provisional; Region: cynX; PRK09705
331111001468	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111001469	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
331111001470	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111001471	putative substrate translocation pore; other site
331111001472	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
331111001473	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
331111001474	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
331111001475	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
331111001476	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
331111001477	lac repressor; Reviewed; Region: lacI; PRK09526
331111001478	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
331111001479	DNA binding site [nucleotide binding]
331111001480	domain linker motif; other site
331111001481	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
331111001482	ligand binding site [chemical binding]; other site
331111001483	dimerization interface (open form) [polypeptide binding]; other site
331111001484	dimerization interface (closed form) [polypeptide binding]; other site
331111001485	DNA-binding transcriptional activator MhpR; Provisional; Region: PRK09834
331111001486	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
331111001487	Bacterial transcriptional regulator; Region: IclR; pfam01614
331111001488	3-(3-hydroxyphenyl)propionate hydroxylase; Validated; Region: mhpA; PRK06183
331111001489	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
331111001490	Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate; Region: MhpB_like; cd07365
331111001491	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
331111001492	putative active site [active]
331111001493	Fe(II) binding site [ion binding]; other site
331111001494	putative dimer interface [polypeptide binding]; other site
331111001495	putative tetramer interface [polypeptide binding]; other site
331111001496	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Region: biphenyl_bphD; TIGR03343
331111001497	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
331111001498	nucleophilic elbow; other site
331111001499	catalytic triad; other site
331111001500	2-keto-4-pentenoate hydratase; Provisional; Region: mhpD; PRK11342
331111001501	acetaldehyde dehydrogenase; Validated; Region: PRK08300
331111001502	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
331111001503	Prokaryotic acetaldehyde dehydrogenase, dimerisation; Region: AcetDehyd-dimer; pfam09290
331111001504	4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195
331111001505	4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943
331111001506	active site
331111001507	catalytic residues [active]
331111001508	metal binding site [ion binding]; metal-binding site
331111001509	DmpG-like communication domain; Region: DmpG_comm; pfam07836
331111001510	putative 3-hydroxyphenylpropionic transporter MhpT; Provisional; Region: PRK11551
331111001511	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111001512	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111001513	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
331111001514	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
331111001515	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
331111001516	S-formylglutathione hydrolase; Region: PLN02442
331111001517	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
331111001518	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
331111001519	substrate binding site [chemical binding]; other site
331111001520	catalytic Zn binding site [ion binding]; other site
331111001521	NAD binding site [chemical binding]; other site
331111001522	structural Zn binding site [ion binding]; other site
331111001523	dimer interface [polypeptide binding]; other site
331111001524	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
331111001525	putative metal binding site [ion binding]; other site
331111001526	putative homodimer interface [polypeptide binding]; other site
331111001527	putative homotetramer interface [polypeptide binding]; other site
331111001528	putative homodimer-homodimer interface [polypeptide binding]; other site
331111001529	putative allosteric switch controlling residues; other site
331111001530	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
331111001531	putative trimer interface [polypeptide binding]; other site
331111001532	putative CoA binding site [chemical binding]; other site
331111001533	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
331111001534	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
331111001535	DXD motif; other site
331111001536	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
331111001537	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
331111001538	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111001539	substrate binding pocket [chemical binding]; other site
331111001540	membrane-bound complex binding site; other site
331111001541	hinge residues; other site
331111001542	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
331111001543	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111001544	dimer interface [polypeptide binding]; other site
331111001545	conserved gate region; other site
331111001546	putative PBP binding loops; other site
331111001547	ABC-ATPase subunit interface; other site
331111001548	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
331111001549	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
331111001550	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
331111001551	dimer interface [polypeptide binding]; other site
331111001552	active site
331111001553	Schiff base residues; other site
331111001554	IS2 transposase TnpB; Reviewed; Region: PRK09409
331111001555	HTH-like domain; Region: HTH_21; pfam13276
331111001556	Integrase core domain; Region: rve; pfam00665
331111001557	Integrase core domain; Region: rve_3; pfam13683
331111001558	IS2 repressor TnpA; Reviewed; Region: PRK09413
331111001559	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111001560	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
331111001561	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
331111001562	Autotransporter beta-domain; Region: Autotransporter; pfam03797
331111001563	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
331111001564	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
331111001565	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
331111001566	microcin B17 transporter; Reviewed; Region: PRK11098
331111001567	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
331111001568	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
331111001569	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
331111001570	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
331111001571	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
331111001572	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
331111001573	anti-RssB factor; Provisional; Region: PRK10244
331111001574	alkaline phosphatase; Provisional; Region: PRK10518
331111001575	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
331111001576	dimer interface [polypeptide binding]; other site
331111001577	active site
331111001578	hypothetical protein; Provisional; Region: PRK11505
331111001579	psiF repeat; Region: PsiF_repeat; pfam07769
331111001580	psiF repeat; Region: PsiF_repeat; pfam07769
331111001581	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
331111001582	MASE2 domain; Region: MASE2; pfam05230
331111001583	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111001584	metal binding site [ion binding]; metal-binding site
331111001585	active site
331111001586	I-site; other site
331111001587	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
331111001588	pyrroline-5-carboxylate reductase; Region: PLN02688
331111001589	hypothetical protein; Validated; Region: PRK00124
331111001590	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
331111001591	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
331111001592	ADP binding site [chemical binding]; other site
331111001593	magnesium binding site [ion binding]; other site
331111001594	putative shikimate binding site; other site
331111001595	hypothetical protein; Provisional; Region: PRK10380
331111001596	hypothetical protein; Provisional; Region: PRK10481
331111001597	hypothetical protein; Provisional; Region: PRK10579
331111001598	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
331111001599	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
331111001600	fructokinase; Reviewed; Region: PRK09557
331111001601	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
331111001602	nucleotide binding site [chemical binding]; other site
331111001603	MFS transport protein AraJ; Provisional; Region: PRK10091
331111001604	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111001605	putative substrate translocation pore; other site
331111001606	exonuclease subunit SbcC; Provisional; Region: PRK10246
331111001607	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111001608	Walker A/P-loop; other site
331111001609	ATP binding site [chemical binding]; other site
331111001610	Q-loop/lid; other site
331111001611	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111001612	ABC transporter signature motif; other site
331111001613	Walker B; other site
331111001614	D-loop; other site
331111001615	H-loop/switch region; other site
331111001616	exonuclease subunit SbcD; Provisional; Region: PRK10966
331111001617	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
331111001618	active site
331111001619	metal binding site [ion binding]; metal-binding site
331111001620	DNA binding site [nucleotide binding]
331111001621	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
331111001622	transcriptional regulator PhoB; Provisional; Region: PRK10161
331111001623	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111001624	active site
331111001625	phosphorylation site [posttranslational modification]
331111001626	intermolecular recognition site; other site
331111001627	dimerization interface [polypeptide binding]; other site
331111001628	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
331111001629	DNA binding site [nucleotide binding]
331111001630	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
331111001631	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
331111001632	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
331111001633	putative active site [active]
331111001634	heme pocket [chemical binding]; other site
331111001635	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111001636	dimer interface [polypeptide binding]; other site
331111001637	phosphorylation site [posttranslational modification]
331111001638	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111001639	ATP binding site [chemical binding]; other site
331111001640	Mg2+ binding site [ion binding]; other site
331111001641	G-X-G motif; other site
331111001642	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
331111001643	putative proline-specific permease; Provisional; Region: proY; PRK10580
331111001644	Spore germination protein; Region: Spore_permease; cl17796
331111001645	maltodextrin glucosidase; Provisional; Region: PRK10785
331111001646	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
331111001647	homodimer interface [polypeptide binding]; other site
331111001648	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
331111001649	active site
331111001650	homodimer interface [polypeptide binding]; other site
331111001651	catalytic site [active]
331111001652	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
331111001653	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
331111001654	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
331111001655	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
331111001656	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
331111001657	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
331111001658	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
331111001659	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
331111001660	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
331111001661	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
331111001662	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
331111001663	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
331111001664	Protein export membrane protein; Region: SecD_SecF; pfam02355
331111001665	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
331111001666	active site
331111001667	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
331111001668	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
331111001669	hypothetical protein; Provisional; Region: PRK11530
331111001670	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
331111001671	ATP cone domain; Region: ATP-cone; pfam03477
331111001672	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
331111001673	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
331111001674	catalytic motif [active]
331111001675	Zn binding site [ion binding]; other site
331111001676	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
331111001677	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
331111001678	homopentamer interface [polypeptide binding]; other site
331111001679	active site
331111001680	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
331111001681	putative RNA binding site [nucleotide binding]; other site
331111001682	thiamine monophosphate kinase; Provisional; Region: PRK05731
331111001683	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
331111001684	ATP binding site [chemical binding]; other site
331111001685	dimerization interface [polypeptide binding]; other site
331111001686	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
331111001687	tetramer interfaces [polypeptide binding]; other site
331111001688	binuclear metal-binding site [ion binding]; other site
331111001689	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
331111001690	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
331111001691	active site
331111001692	catalytic tetrad [active]
331111001693	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
331111001694	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
331111001695	TPP-binding site; other site
331111001696	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
331111001697	PYR/PP interface [polypeptide binding]; other site
331111001698	dimer interface [polypeptide binding]; other site
331111001699	TPP binding site [chemical binding]; other site
331111001700	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
331111001701	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
331111001702	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
331111001703	substrate binding pocket [chemical binding]; other site
331111001704	chain length determination region; other site
331111001705	substrate-Mg2+ binding site; other site
331111001706	catalytic residues [active]
331111001707	aspartate-rich region 1; other site
331111001708	active site lid residues [active]
331111001709	aspartate-rich region 2; other site
331111001710	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
331111001711	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
331111001712	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
331111001713	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
331111001714	Ligand Binding Site [chemical binding]; other site
331111001715	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
331111001716	active site residue [active]
331111001717	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
331111001718	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
331111001719	conserved cys residue [active]
331111001720	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
331111001721	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
331111001722	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
331111001723	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
331111001724	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
331111001725	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111001726	Major Facilitator Superfamily; Region: MFS_1; pfam07690
331111001727	putative substrate translocation pore; other site
331111001728	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
331111001729	Sel1 repeat; Region: Sel1; pfam08238
331111001730	Sel1-like repeats; Region: SEL1; smart00671
331111001731	Sel1-like repeats; Region: SEL1; smart00671
331111001732	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
331111001733	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
331111001734	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
331111001735	UbiA prenyltransferase family; Region: UbiA; pfam01040
331111001736	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
331111001737	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
331111001738	Subunit I/III interface [polypeptide binding]; other site
331111001739	Subunit III/IV interface [polypeptide binding]; other site
331111001740	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
331111001741	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
331111001742	D-pathway; other site
331111001743	Putative ubiquinol binding site [chemical binding]; other site
331111001744	Low-spin heme (heme b) binding site [chemical binding]; other site
331111001745	Putative water exit pathway; other site
331111001746	Binuclear center (heme o3/CuB) [ion binding]; other site
331111001747	K-pathway; other site
331111001748	Putative proton exit pathway; other site
331111001749	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
331111001750	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
331111001751	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
331111001752	muropeptide transporter; Reviewed; Region: ampG; PRK11902
331111001753	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111001754	putative substrate translocation pore; other site
331111001755	hypothetical protein; Provisional; Region: PRK11627
331111001756	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
331111001757	transcriptional regulator BolA; Provisional; Region: PRK11628
331111001758	trigger factor; Provisional; Region: tig; PRK01490
331111001759	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
331111001760	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
331111001761	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
331111001762	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
331111001763	oligomer interface [polypeptide binding]; other site
331111001764	active site residues [active]
331111001765	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
331111001766	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
331111001767	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111001768	Walker A motif; other site
331111001769	ATP binding site [chemical binding]; other site
331111001770	Walker B motif; other site
331111001771	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
331111001772	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
331111001773	Found in ATP-dependent protease La (LON); Region: LON; smart00464
331111001774	Found in ATP-dependent protease La (LON); Region: LON; smart00464
331111001775	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111001776	Walker A motif; other site
331111001777	ATP binding site [chemical binding]; other site
331111001778	Walker B motif; other site
331111001779	arginine finger; other site
331111001780	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
331111001781	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
331111001782	IHF dimer interface [polypeptide binding]; other site
331111001783	IHF - DNA interface [nucleotide binding]; other site
331111001784	periplasmic folding chaperone; Provisional; Region: PRK10788
331111001785	SurA N-terminal domain; Region: SurA_N_3; cl07813
331111001786	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
331111001787	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
331111001788	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
331111001789	active site
331111001790	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
331111001791	Ligand Binding Site [chemical binding]; other site
331111001792	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
331111001793	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
331111001794	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
331111001795	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
331111001796	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111001797	active site
331111001798	motif I; other site
331111001799	motif II; other site
331111001800	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
331111001801	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
331111001802	putative DNA binding site [nucleotide binding]; other site
331111001803	putative Zn2+ binding site [ion binding]; other site
331111001804	AsnC family; Region: AsnC_trans_reg; pfam01037
331111001805	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
331111001806	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
331111001807	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111001808	Walker A/P-loop; other site
331111001809	ATP binding site [chemical binding]; other site
331111001810	Q-loop/lid; other site
331111001811	ABC transporter signature motif; other site
331111001812	Walker B; other site
331111001813	D-loop; other site
331111001814	H-loop/switch region; other site
331111001815	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
331111001816	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
331111001817	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
331111001818	Walker A/P-loop; other site
331111001819	ATP binding site [chemical binding]; other site
331111001820	Q-loop/lid; other site
331111001821	ABC transporter signature motif; other site
331111001822	Walker B; other site
331111001823	D-loop; other site
331111001824	H-loop/switch region; other site
331111001825	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
331111001826	Nitrogen regulatory protein P-II; Region: P-II; smart00938
331111001827	ammonium transporter; Provisional; Region: PRK10666
331111001828	acyl-CoA thioesterase II; Provisional; Region: PRK10526
331111001829	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
331111001830	active site
331111001831	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
331111001832	catalytic triad [active]
331111001833	dimer interface [polypeptide binding]; other site
331111001834	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
331111001835	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
331111001836	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
331111001837	DNA binding site [nucleotide binding]
331111001838	active site
331111001839	Protein of unknown function (DUF1428); Region: DUF1428; cl02319
331111001840	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
331111001841	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
331111001842	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
331111001843	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
331111001844	maltose O-acetyltransferase; Provisional; Region: PRK10092
331111001845	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
331111001846	active site
331111001847	substrate binding site [chemical binding]; other site
331111001848	trimer interface [polypeptide binding]; other site
331111001849	CoA binding site [chemical binding]; other site
331111001850	Biofilm formation regulator YbaJ; Region: YbaJ; pfam10757
331111001851	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
331111001852	Protein export membrane protein; Region: SecD_SecF; cl14618
331111001853	Protein export membrane protein; Region: SecD_SecF; cl14618
331111001854	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
331111001855	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
331111001856	HlyD family secretion protein; Region: HlyD_3; pfam13437
331111001857	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
331111001858	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
331111001859	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
331111001860	hypothetical protein; Provisional; Region: PRK11281
331111001861	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
331111001862	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
331111001863	Mechanosensitive ion channel; Region: MS_channel; pfam00924
331111001864	hypothetical protein; Provisional; Region: PRK11038
331111001865	primosomal replication protein N''; Provisional; Region: PRK10093
331111001866	hypothetical protein; Provisional; Region: PRK10527
331111001867	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
331111001868	active site
331111001869	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
331111001870	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111001871	Walker A motif; other site
331111001872	ATP binding site [chemical binding]; other site
331111001873	Walker B motif; other site
331111001874	DNA polymerase III subunit delta'; Validated; Region: PRK08485
331111001875	arginine finger; other site
331111001876	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
331111001877	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
331111001878	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
331111001879	hypothetical protein; Validated; Region: PRK00153
331111001880	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
331111001881	RecR protein; Region: RecR; pfam02132
331111001882	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
331111001883	putative active site [active]
331111001884	putative metal-binding site [ion binding]; other site
331111001885	tetramer interface [polypeptide binding]; other site
331111001886	heat shock protein 90; Provisional; Region: PRK05218
331111001887	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111001888	ATP binding site [chemical binding]; other site
331111001889	Mg2+ binding site [ion binding]; other site
331111001890	G-X-G motif; other site
331111001891	adenylate kinase; Reviewed; Region: adk; PRK00279
331111001892	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
331111001893	AMP-binding site [chemical binding]; other site
331111001894	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
331111001895	ferrochelatase; Region: hemH; TIGR00109
331111001896	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
331111001897	C-terminal domain interface [polypeptide binding]; other site
331111001898	active site
331111001899	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
331111001900	active site
331111001901	N-terminal domain interface [polypeptide binding]; other site
331111001902	acetyl esterase; Provisional; Region: PRK10162
331111001903	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
331111001904	inosine/guanosine kinase; Provisional; Region: PRK15074
331111001905	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
331111001906	putative cation:proton antiport protein; Provisional; Region: PRK10669
331111001907	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
331111001908	TrkA-N domain; Region: TrkA_N; pfam02254
331111001909	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111001910	Major Facilitator Superfamily; Region: MFS_1; pfam07690
331111001911	putative substrate translocation pore; other site
331111001912	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
331111001913	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
331111001914	active site
331111001915	metal binding site [ion binding]; metal-binding site
331111001916	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
331111001917	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
331111001918	putative deacylase active site [active]
331111001919	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
331111001920	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
331111001921	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111001922	non-specific DNA binding site [nucleotide binding]; other site
331111001923	salt bridge; other site
331111001924	sequence-specific DNA binding site [nucleotide binding]; other site
331111001925	copper exporting ATPase; Provisional; Region: copA; PRK10671
331111001926	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
331111001927	metal-binding site [ion binding]
331111001928	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
331111001929	metal-binding site [ion binding]
331111001930	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
331111001931	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111001932	motif II; other site
331111001933	glutaminase; Reviewed; Region: PRK12356
331111001934	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
331111001935	amino acid transporter; Region: 2A0306; TIGR00909
331111001936	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
331111001937	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
331111001938	DNA binding residues [nucleotide binding]
331111001939	dimer interface [polypeptide binding]; other site
331111001940	copper binding site [ion binding]; other site
331111001941	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
331111001942	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
331111001943	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
331111001944	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
331111001945	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111001946	Walker A/P-loop; other site
331111001947	ATP binding site [chemical binding]; other site
331111001948	Q-loop/lid; other site
331111001949	ABC transporter signature motif; other site
331111001950	Walker B; other site
331111001951	D-loop; other site
331111001952	H-loop/switch region; other site
331111001953	Uncharacterized protein family (UPF0014); Region: UPF0014; pfam03649
331111001954	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
331111001955	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
331111001956	oxidoreductase; Provisional; Region: PRK08017
331111001957	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
331111001958	NADP binding site [chemical binding]; other site
331111001959	active site
331111001960	steroid binding site; other site
331111001961	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
331111001962	active site
331111001963	catalytic triad [active]
331111001964	oxyanion hole [active]
331111001965	switch loop; other site
331111001966	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
331111001967	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
331111001968	Walker A/P-loop; other site
331111001969	ATP binding site [chemical binding]; other site
331111001970	Q-loop/lid; other site
331111001971	ABC transporter signature motif; other site
331111001972	Walker B; other site
331111001973	D-loop; other site
331111001974	H-loop/switch region; other site
331111001975	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
331111001976	FtsX-like permease family; Region: FtsX; pfam02687
331111001977	FtsX-like permease family; Region: FtsX; pfam02687
331111001978	PAAR motif; Region: PAAR_motif; cl15808
331111001979	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
331111001980	RHS Repeat; Region: RHS_repeat; pfam05593
331111001981	RHS Repeat; Region: RHS_repeat; pfam05593
331111001982	RHS Repeat; Region: RHS_repeat; pfam05593
331111001983	RHS Repeat; Region: RHS_repeat; pfam05593
331111001984	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
331111001985	RHS Repeat; Region: RHS_repeat; pfam05593
331111001986	RHS Repeat; Region: RHS_repeat; pfam05593
331111001987	RHS protein; Region: RHS; pfam03527
331111001988	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
331111001989	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
331111001990	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
331111001991	RHS protein; Region: RHS; pfam03527
331111001992	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
331111001993	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
331111001994	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
331111001995	active site residue [active]
331111001996	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
331111001997	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111001998	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
331111001999	dimerization interface [polypeptide binding]; other site
331111002000	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
331111002001	ureidoglycolate hydrolase; Provisional; Region: PRK03606
331111002002	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
331111002003	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
331111002004	Bacterial transcriptional regulator; Region: IclR; pfam01614
331111002005	glyoxylate carboligase; Provisional; Region: PRK11269
331111002006	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
331111002007	PYR/PP interface [polypeptide binding]; other site
331111002008	dimer interface [polypeptide binding]; other site
331111002009	TPP binding site [chemical binding]; other site
331111002010	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
331111002011	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
331111002012	TPP-binding site [chemical binding]; other site
331111002013	hydroxypyruvate isomerase; Provisional; Region: PRK09997
331111002014	tartronate semialdehyde reductase; Provisional; Region: PRK15059
331111002015	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
331111002016	nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; Region: SLC-NCS1sbd; cd10323
331111002017	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
331111002018	Na binding site [ion binding]; other site
331111002019	substrate binding site [chemical binding]; other site
331111002020	allantoinase; Provisional; Region: PRK08044
331111002021	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
331111002022	active site
331111002023	putative uracil/xanthine transporter; Provisional; Region: PRK11412
331111002024	glycerate kinase II; Provisional; Region: PRK09932
331111002025	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
331111002026	Protein of unknown function (DUF861); Region: Cupin_3; pfam05899
331111002027	Cupin domain; Region: Cupin_2; cl17218
331111002028	allantoate amidohydrolase; Region: AllC; TIGR03176
331111002029	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
331111002030	active site
331111002031	metal binding site [ion binding]; metal-binding site
331111002032	dimer interface [polypeptide binding]; other site
331111002033	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
331111002034	membrane protein FdrA; Validated; Region: PRK06091
331111002035	CoA binding domain; Region: CoA_binding; pfam02629
331111002036	CoA-ligase; Region: Ligase_CoA; pfam00549
331111002037	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
331111002038	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
331111002039	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
331111002040	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
331111002041	putative substrate binding site [chemical binding]; other site
331111002042	nucleotide binding site [chemical binding]; other site
331111002043	nucleotide binding site [chemical binding]; other site
331111002044	homodimer interface [polypeptide binding]; other site
331111002045	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
331111002046	ATP-grasp domain; Region: ATP-grasp; pfam02222
331111002047	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
331111002048	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
331111002049	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
331111002050	putative active site [active]
331111002051	putative metal binding site [ion binding]; other site
331111002052	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
331111002053	substrate binding site [chemical binding]; other site
331111002054	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
331111002055	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
331111002056	active site
331111002057	HIGH motif; other site
331111002058	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
331111002059	KMSKS motif; other site
331111002060	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
331111002061	tRNA binding surface [nucleotide binding]; other site
331111002062	anticodon binding site; other site
331111002063	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
331111002064	ribosome-associated protein; Provisional; Region: PRK11507
331111002065	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
331111002066	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
331111002067	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
331111002068	homodimer interface [polypeptide binding]; other site
331111002069	NADP binding site [chemical binding]; other site
331111002070	substrate binding site [chemical binding]; other site
331111002071	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
331111002072	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
331111002073	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
331111002074	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
331111002075	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
331111002076	transcriptional regulator FimZ; Provisional; Region: PRK09935
331111002077	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111002078	active site
331111002079	phosphorylation site [posttranslational modification]
331111002080	intermolecular recognition site; other site
331111002081	dimerization interface [polypeptide binding]; other site
331111002082	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111002083	DNA binding residues [nucleotide binding]
331111002084	dimerization interface [polypeptide binding]; other site
331111002085	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
331111002086	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111002087	hypothetical protein; Provisional; Region: PRK09936
331111002088	bacteriophage N4 receptor, outer membrane subunit; Provisional; Region: PRK09782
331111002089	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
331111002090	TPR motif; other site
331111002091	binding surface
331111002092	Bacteriophage N adsorption protein A C-term; Region: NfrA_C; pfam13283
331111002093	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
331111002094	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
331111002095	Transposase [DNA replication, recombination, and repair]; Region: COG5433
331111002096	Transposase [DNA replication, recombination, and repair]; Region: COG5433
331111002097	PAAR motif; Region: PAAR_motif; pfam05488
331111002098	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
331111002099	RHS Repeat; Region: RHS_repeat; cl11982
331111002100	RHS Repeat; Region: RHS_repeat; pfam05593
331111002101	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
331111002102	RHS Repeat; Region: RHS_repeat; pfam05593
331111002103	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
331111002104	RHS Repeat; Region: RHS_repeat; pfam05593
331111002105	RHS Repeat; Region: RHS_repeat; cl11982
331111002106	RHS Repeat; Region: RHS_repeat; pfam05593
331111002107	RHS Repeat; Region: RHS_repeat; cl11982
331111002108	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
331111002109	RHS Repeat; Region: RHS_repeat; cl11982
331111002110	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
331111002111	Uncharacterized conserved protein [Function unknown]; Region: COG5435
331111002112	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
331111002113	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
331111002114	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
331111002115	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
331111002116	sensor kinase CusS; Provisional; Region: PRK09835
331111002117	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
331111002118	dimerization interface [polypeptide binding]; other site
331111002119	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111002120	dimer interface [polypeptide binding]; other site
331111002121	phosphorylation site [posttranslational modification]
331111002122	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111002123	ATP binding site [chemical binding]; other site
331111002124	Mg2+ binding site [ion binding]; other site
331111002125	G-X-G motif; other site
331111002126	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
331111002127	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111002128	active site
331111002129	phosphorylation site [posttranslational modification]
331111002130	intermolecular recognition site; other site
331111002131	dimerization interface [polypeptide binding]; other site
331111002132	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
331111002133	DNA binding site [nucleotide binding]
331111002134	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
331111002135	periplasmic copper-binding protein; Provisional; Region: PRK09838
331111002136	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
331111002137	HlyD family secretion protein; Region: HlyD_3; pfam13437
331111002138	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
331111002139	phenylalanine transporter; Provisional; Region: PRK10249
331111002140	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
331111002141	Mechanosensitive ion channel; Region: MS_channel; pfam00924
331111002142	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
331111002143	dimer interface [polypeptide binding]; other site
331111002144	FMN binding site [chemical binding]; other site
331111002145	hypothetical protein; Provisional; Region: PRK10250
331111002146	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
331111002147	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
331111002148	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
331111002149	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
331111002150	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
331111002151	outer membrane receptor FepA; Provisional; Region: PRK13524
331111002152	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
331111002153	N-terminal plug; other site
331111002154	ligand-binding site [chemical binding]; other site
331111002155	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
331111002156	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
331111002157	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
331111002158	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
331111002159	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
331111002160	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
331111002161	acyl-activating enzyme (AAE) consensus motif; other site
331111002162	AMP binding site [chemical binding]; other site
331111002163	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
331111002164	LPS O-antigen length regulator; Provisional; Region: PRK10381
331111002165	Chain length determinant protein; Region: Wzz; pfam02706
331111002166	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
331111002167	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
331111002168	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
331111002169	Walker A/P-loop; other site
331111002170	ATP binding site [chemical binding]; other site
331111002171	Q-loop/lid; other site
331111002172	ABC transporter signature motif; other site
331111002173	Walker B; other site
331111002174	D-loop; other site
331111002175	H-loop/switch region; other site
331111002176	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
331111002177	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
331111002178	ABC-ATPase subunit  interface; other site
331111002179	dimer interface [polypeptide binding]; other site
331111002180	putative PBP binding regions; other site
331111002181	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
331111002182	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
331111002183	ABC-ATPase subunit  interface; other site
331111002184	dimer interface [polypeptide binding]; other site
331111002185	putative PBP binding regions; other site
331111002186	enterobactin exporter EntS; Provisional; Region: PRK10489
331111002187	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111002188	putative substrate translocation pore; other site
331111002189	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
331111002190	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
331111002191	siderophore binding site; other site
331111002192	isochorismate synthase EntC; Provisional; Region: PRK15016
331111002193	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
331111002194	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
331111002195	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
331111002196	acyl-activating enzyme (AAE) consensus motif; other site
331111002197	active site
331111002198	AMP binding site [chemical binding]; other site
331111002199	substrate binding site [chemical binding]; other site
331111002200	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
331111002201	hydrophobic substrate binding pocket; other site
331111002202	Isochorismatase family; Region: Isochorismatase; pfam00857
331111002203	active site
331111002204	conserved cis-peptide bond; other site
331111002205	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
331111002206	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
331111002207	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
331111002208	putative NAD(P) binding site [chemical binding]; other site
331111002209	active site
331111002210	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
331111002211	CoenzymeA binding site [chemical binding]; other site
331111002212	subunit interaction site [polypeptide binding]; other site
331111002213	PHB binding site; other site
331111002214	carbon starvation protein A; Provisional; Region: PRK15015
331111002215	Carbon starvation protein CstA; Region: CstA; pfam02554
331111002216	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
331111002217	Uncharacterized small protein [Function unknown]; Region: COG2879
331111002218	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
331111002219	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
331111002220	putative active site [active]
331111002221	metal binding site [ion binding]; metal-binding site
331111002222	methionine aminotransferase; Validated; Region: PRK09082
331111002223	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
331111002224	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111002225	homodimer interface [polypeptide binding]; other site
331111002226	catalytic residue [active]
331111002227	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
331111002228	ParB-like nuclease domain; Region: ParBc; pfam02195
331111002229	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
331111002230	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
331111002231	Active Sites [active]
331111002232	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
331111002233	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
331111002234	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111002235	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
331111002236	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
331111002237	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
331111002238	dimerization domain [polypeptide binding]; other site
331111002239	dimer interface [polypeptide binding]; other site
331111002240	catalytic residues [active]
331111002241	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
331111002242	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
331111002243	dimer interface [polypeptide binding]; other site
331111002244	decamer (pentamer of dimers) interface [polypeptide binding]; other site
331111002245	catalytic triad [active]
331111002246	peroxidatic and resolving cysteines [active]
331111002247	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
331111002248	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
331111002249	catalytic residue [active]
331111002250	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
331111002251	catalytic residues [active]
331111002252	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
331111002253	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111002254	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
331111002255	Ligand Binding Site [chemical binding]; other site
331111002256	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
331111002257	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
331111002258	NAD binding site [chemical binding]; other site
331111002259	catalytic Zn binding site [ion binding]; other site
331111002260	structural Zn binding site [ion binding]; other site
331111002261	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
331111002262	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
331111002263	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
331111002264	B1 nucleotide binding pocket [chemical binding]; other site
331111002265	B2 nucleotide binding pocket [chemical binding]; other site
331111002266	CAS motifs; other site
331111002267	active site
331111002268	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
331111002269	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
331111002270	transmembrane helices; other site
331111002271	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
331111002272	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
331111002273	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
331111002274	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
331111002275	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
331111002276	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
331111002277	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
331111002278	putative active site [active]
331111002279	heme pocket [chemical binding]; other site
331111002280	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111002281	ATP binding site [chemical binding]; other site
331111002282	Mg2+ binding site [ion binding]; other site
331111002283	G-X-G motif; other site
331111002284	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
331111002285	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111002286	active site
331111002287	phosphorylation site [posttranslational modification]
331111002288	intermolecular recognition site; other site
331111002289	dimerization interface [polypeptide binding]; other site
331111002290	Transcriptional regulator; Region: CitT; pfam12431
331111002291	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
331111002292	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
331111002293	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
331111002294	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
331111002295	DNA-binding site [nucleotide binding]; DNA binding site
331111002296	RNA-binding motif; other site
331111002297	chromosome condensation membrane protein; Provisional; Region: PRK14196
331111002298	Predicted amidohydrolase [General function prediction only]; Region: COG0388
331111002299	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
331111002300	putative active site [active]
331111002301	catalytic triad [active]
331111002302	putative dimer interface [polypeptide binding]; other site
331111002303	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
331111002304	lipoyl synthase; Provisional; Region: PRK05481
331111002305	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111002306	FeS/SAM binding site; other site
331111002307	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
331111002308	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111002309	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
331111002310	substrate binding pocket [chemical binding]; other site
331111002311	dimerization interface [polypeptide binding]; other site
331111002312	lipoate-protein ligase B; Provisional; Region: PRK14342
331111002313	hypothetical protein; Provisional; Region: PRK04998
331111002314	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
331111002315	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
331111002316	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
331111002317	rare lipoprotein A; Provisional; Region: PRK10672
331111002318	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
331111002319	Sporulation related domain; Region: SPOR; pfam05036
331111002320	cell wall shape-determining protein; Provisional; Region: PRK10794
331111002321	penicillin-binding protein 2; Provisional; Region: PRK10795
331111002322	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
331111002323	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
331111002324	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
331111002325	ribosome-associated protein; Provisional; Region: PRK11538
331111002326	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
331111002327	catalytic core [active]
331111002328	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
331111002329	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
331111002330	active site
331111002331	(T/H)XGH motif; other site
331111002332	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
331111002333	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
331111002334	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
331111002335	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
331111002336	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
331111002337	HIGH motif; other site
331111002338	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
331111002339	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
331111002340	active site
331111002341	KMSKS motif; other site
331111002342	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
331111002343	tRNA binding surface [nucleotide binding]; other site
331111002344	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
331111002345	hypothetical protein; Provisional; Region: PRK11032
331111002346	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
331111002347	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
331111002348	Sel1-like repeats; Region: SEL1; smart00671
331111002349	Sel1-like repeats; Region: SEL1; smart00671
331111002350	Sel1-like repeats; Region: SEL1; smart00671
331111002351	Sel1-like repeats; Region: SEL1; smart00671
331111002352	Sel1-like repeats; Region: SEL1; smart00671
331111002353	Sel1-like repeats; Region: SEL1; smart00671
331111002354	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
331111002355	DnaJ molecular chaperone homology domain; Region: DnaJ; smart00271
331111002356	HSP70 interaction site [polypeptide binding]; other site
331111002357	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
331111002358	Sel1-like repeats; Region: SEL1; smart00671
331111002359	Sel1-like repeats; Region: SEL1; smart00671
331111002360	Sel1-like repeats; Region: SEL1; smart00671
331111002361	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
331111002362	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
331111002363	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
331111002364	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
331111002365	nucleotide binding site [chemical binding]; other site
331111002366	putative NEF/HSP70 interaction site [polypeptide binding]; other site
331111002367	SBD interface [polypeptide binding]; other site
331111002368	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
331111002369	active site
331111002370	tetramer interface [polypeptide binding]; other site
331111002371	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
331111002372	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
331111002373	Walker A/P-loop; other site
331111002374	ATP binding site [chemical binding]; other site
331111002375	Q-loop/lid; other site
331111002376	ABC transporter signature motif; other site
331111002377	Walker B; other site
331111002378	D-loop; other site
331111002379	H-loop/switch region; other site
331111002380	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
331111002381	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111002382	dimer interface [polypeptide binding]; other site
331111002383	conserved gate region; other site
331111002384	putative PBP binding loops; other site
331111002385	ABC-ATPase subunit interface; other site
331111002386	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
331111002387	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111002388	dimer interface [polypeptide binding]; other site
331111002389	conserved gate region; other site
331111002390	putative PBP binding loops; other site
331111002391	ABC-ATPase subunit interface; other site
331111002392	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
331111002393	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111002394	substrate binding pocket [chemical binding]; other site
331111002395	membrane-bound complex binding site; other site
331111002396	hinge residues; other site
331111002397	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
331111002398	Uncharacterized conserved protein [Function unknown]; Region: COG3391
331111002399	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
331111002400	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
331111002401	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
331111002402	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
331111002403	putative active site [active]
331111002404	catalytic triad [active]
331111002405	putative dimer interface [polypeptide binding]; other site
331111002406	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
331111002407	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
331111002408	Transporter associated domain; Region: CorC_HlyC; smart01091
331111002409	metal-binding heat shock protein; Provisional; Region: PRK00016
331111002410	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
331111002411	PhoH-like protein; Region: PhoH; pfam02562
331111002412	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
331111002413	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
331111002414	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111002415	FeS/SAM binding site; other site
331111002416	TRAM domain; Region: TRAM; pfam01938
331111002417	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
331111002418	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
331111002419	asparagine synthetase B; Provisional; Region: asnB; PRK09431
331111002420	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
331111002421	active site
331111002422	dimer interface [polypeptide binding]; other site
331111002423	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
331111002424	Ligand Binding Site [chemical binding]; other site
331111002425	Molecular Tunnel; other site
331111002426	UMP phosphatase; Provisional; Region: PRK10444
331111002427	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111002428	active site
331111002429	motif I; other site
331111002430	motif II; other site
331111002431	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111002432	MarR family; Region: MarR; pfam01047
331111002433	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
331111002434	ROK family; Region: ROK; pfam00480
331111002435	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
331111002436	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
331111002437	active site
331111002438	dimer interface [polypeptide binding]; other site
331111002439	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
331111002440	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
331111002441	active site
331111002442	trimer interface [polypeptide binding]; other site
331111002443	allosteric site; other site
331111002444	active site lid [active]
331111002445	hexamer (dimer of trimers) interface [polypeptide binding]; other site
331111002446	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
331111002447	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
331111002448	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
331111002449	active site turn [active]
331111002450	phosphorylation site [posttranslational modification]
331111002451	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
331111002452	HPr interaction site; other site
331111002453	glycerol kinase (GK) interaction site [polypeptide binding]; other site
331111002454	active site
331111002455	phosphorylation site [posttranslational modification]
331111002456	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
331111002457	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
331111002458	active site
331111002459	HIGH motif; other site
331111002460	nucleotide binding site [chemical binding]; other site
331111002461	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
331111002462	KMSKS motif; other site
331111002463	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
331111002464	outer membrane porin, OprD family; Region: OprD; pfam03573
331111002465	YbfN-like lipoprotein; Region: YbfN; pfam13982
331111002466	ferric uptake regulator; Provisional; Region: fur; PRK09462
331111002467	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
331111002468	metal binding site 2 [ion binding]; metal-binding site
331111002469	putative DNA binding helix; other site
331111002470	metal binding site 1 [ion binding]; metal-binding site
331111002471	dimer interface [polypeptide binding]; other site
331111002472	structural Zn2+ binding site [ion binding]; other site
331111002473	flavodoxin FldA; Validated; Region: PRK09267
331111002474	LexA regulated protein; Provisional; Region: PRK11675
331111002475	acyl-CoA esterase; Provisional; Region: PRK10673
331111002476	PGAP1-like protein; Region: PGAP1; pfam07819
331111002477	replication initiation regulator SeqA; Provisional; Region: PRK11187
331111002478	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
331111002479	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
331111002480	active site
331111002481	substrate binding site [chemical binding]; other site
331111002482	metal binding site [ion binding]; metal-binding site
331111002483	putrescine transporter; Provisional; Region: potE; PRK10655
331111002484	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
331111002485	ornithine decarboxylase; Provisional; Region: PRK13578
331111002486	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
331111002487	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
331111002488	homodimer interface [polypeptide binding]; other site
331111002489	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111002490	catalytic residue [active]
331111002491	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
331111002492	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
331111002493	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111002494	active site
331111002495	phosphorylation site [posttranslational modification]
331111002496	intermolecular recognition site; other site
331111002497	dimerization interface [polypeptide binding]; other site
331111002498	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
331111002499	DNA binding site [nucleotide binding]
331111002500	sensor protein KdpD; Provisional; Region: PRK10490
331111002501	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
331111002502	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
331111002503	Ligand Binding Site [chemical binding]; other site
331111002504	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
331111002505	GAF domain; Region: GAF_3; pfam13492
331111002506	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111002507	dimer interface [polypeptide binding]; other site
331111002508	phosphorylation site [posttranslational modification]
331111002509	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111002510	ATP binding site [chemical binding]; other site
331111002511	Mg2+ binding site [ion binding]; other site
331111002512	G-X-G motif; other site
331111002513	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
331111002514	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
331111002515	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
331111002516	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
331111002517	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
331111002518	PAAR motif; Region: PAAR_motif; cl15808
331111002519	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
331111002520	RHS Repeat; Region: RHS_repeat; pfam05593
331111002521	RHS Repeat; Region: RHS_repeat; pfam05593
331111002522	RHS Repeat; Region: RHS_repeat; cl11982
331111002523	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
331111002524	RHS Repeat; Region: RHS_repeat; pfam05593
331111002525	RHS Repeat; Region: RHS_repeat; pfam05593
331111002526	RHS protein; Region: RHS; pfam03527
331111002527	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
331111002528	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
331111002529	RHS protein; Region: RHS; pfam03527
331111002530	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
331111002531	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
331111002532	hypothetical protein; Provisional; Region: PRK10167
331111002533	Uncharacterized conserved protein [Function unknown]; Region: COG3272
331111002534	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
331111002535	DNA photolyase; Region: DNA_photolyase; pfam00875
331111002536	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
331111002537	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111002538	putative substrate translocation pore; other site
331111002539	POT family; Region: PTR2; pfam00854
331111002540	Uncharacterized conserved protein [Function unknown]; Region: COG0327
331111002541	metal-binding protein; Provisional; Region: PRK10799
331111002542	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
331111002543	sensor histidine kinase inhibitor, KipI family; Region: TIGR00370
331111002544	biotin-dependent carboxylase uncharacterized domain; Region: urea_amlyse_rel; TIGR00724
331111002545	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
331111002546	putative active site [active]
331111002547	endonuclease VIII; Provisional; Region: PRK10445
331111002548	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
331111002549	DNA binding site [nucleotide binding]
331111002550	catalytic residue [active]
331111002551	putative catalytic residues [active]
331111002552	H2TH interface [polypeptide binding]; other site
331111002553	intercalation triad [nucleotide binding]; other site
331111002554	substrate specificity determining residue; other site
331111002555	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
331111002556	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
331111002557	Fimbrial protein; Region: Fimbrial; pfam00419
331111002558	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
331111002559	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
331111002560	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
331111002561	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
331111002562	PapC N-terminal domain; Region: PapC_N; pfam13954
331111002563	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
331111002564	PapC C-terminal domain; Region: PapC_C; pfam13953
331111002565	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
331111002566	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
331111002567	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
331111002568	dimer interface [polypeptide binding]; other site
331111002569	active site
331111002570	citrylCoA binding site [chemical binding]; other site
331111002571	NADH binding [chemical binding]; other site
331111002572	cationic pore residues; other site
331111002573	oxalacetate/citrate binding site [chemical binding]; other site
331111002574	coenzyme A binding site [chemical binding]; other site
331111002575	catalytic triad [active]
331111002576	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
331111002577	Iron-sulfur protein interface; other site
331111002578	proximal quinone binding site [chemical binding]; other site
331111002579	SdhD (CybS) interface [polypeptide binding]; other site
331111002580	proximal heme binding site [chemical binding]; other site
331111002581	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
331111002582	SdhC subunit interface [polypeptide binding]; other site
331111002583	proximal heme binding site [chemical binding]; other site
331111002584	cardiolipin binding site; other site
331111002585	Iron-sulfur protein interface; other site
331111002586	proximal quinone binding site [chemical binding]; other site
331111002587	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
331111002588	L-aspartate oxidase; Provisional; Region: PRK06175
331111002589	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
331111002590	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
331111002591	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
331111002592	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
331111002593	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
331111002594	TPP-binding site [chemical binding]; other site
331111002595	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
331111002596	dimer interface [polypeptide binding]; other site
331111002597	PYR/PP interface [polypeptide binding]; other site
331111002598	TPP binding site [chemical binding]; other site
331111002599	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
331111002600	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
331111002601	E3 interaction surface; other site
331111002602	lipoyl attachment site [posttranslational modification]; other site
331111002603	e3 binding domain; Region: E3_binding; pfam02817
331111002604	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
331111002605	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
331111002606	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
331111002607	CoA-ligase; Region: Ligase_CoA; pfam00549
331111002608	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
331111002609	CoA binding domain; Region: CoA_binding; smart00881
331111002610	CoA-ligase; Region: Ligase_CoA; pfam00549
331111002611	DNA-binding transcriptional repressor MngR; Provisional; Region: PRK09764
331111002612	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111002613	DNA-binding site [nucleotide binding]; DNA binding site
331111002614	UTRA domain; Region: UTRA; pfam07702
331111002615	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
331111002616	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
331111002617	active site
331111002618	phosphorylation site [posttranslational modification]
331111002619	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
331111002620	active site
331111002621	P-loop; other site
331111002622	phosphorylation site [posttranslational modification]
331111002623	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
331111002624	alpha-mannosidase; Provisional; Region: PRK09819
331111002625	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
331111002626	active site
331111002627	metal binding site [ion binding]; metal-binding site
331111002628	catalytic site [active]
331111002629	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
331111002630	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
331111002631	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
331111002632	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
331111002633	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
331111002634	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
331111002635	hypothetical protein; Provisional; Region: PRK10588
331111002636	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
331111002637	active site
331111002638	colicin uptake protein TolQ; Provisional; Region: PRK10801
331111002639	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
331111002640	colicin uptake protein TolR; Provisional; Region: PRK11024
331111002641	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
331111002642	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
331111002643	TolA C-terminal; Region: TolA; pfam06519
331111002644	translocation protein TolB; Provisional; Region: tolB; PRK03629
331111002645	TolB amino-terminal domain; Region: TolB_N; pfam04052
331111002646	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
331111002647	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
331111002648	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
331111002649	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
331111002650	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
331111002651	ligand binding site [chemical binding]; other site
331111002652	tol-pal system protein YbgF; Provisional; Region: PRK10803
331111002653	Tetratricopeptide repeat; Region: TPR_6; pfam13174
331111002654	Tetratricopeptide repeat; Region: TPR_6; pfam13174
331111002655	quinolinate synthetase; Provisional; Region: PRK09375
331111002656	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
331111002657	zinc transporter ZitB; Provisional; Region: PRK03557
331111002658	YbgS-like protein; Region: YbgS; pfam13985
331111002659	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
331111002660	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
331111002661	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
331111002662	catalytic core [active]
331111002663	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
331111002664	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
331111002665	active site
331111002666	catalytic residues [active]
331111002667	galactokinase; Provisional; Region: PRK05101
331111002668	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
331111002669	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
331111002670	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
331111002671	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
331111002672	dimer interface [polypeptide binding]; other site
331111002673	active site
331111002674	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
331111002675	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
331111002676	NAD binding site [chemical binding]; other site
331111002677	homodimer interface [polypeptide binding]; other site
331111002678	active site
331111002679	substrate binding site [chemical binding]; other site
331111002680	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
331111002681	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
331111002682	Walker A/P-loop; other site
331111002683	ATP binding site [chemical binding]; other site
331111002684	Q-loop/lid; other site
331111002685	ABC transporter signature motif; other site
331111002686	Walker B; other site
331111002687	D-loop; other site
331111002688	H-loop/switch region; other site
331111002689	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111002690	Walker A/P-loop; other site
331111002691	ATP binding site [chemical binding]; other site
331111002692	Q-loop/lid; other site
331111002693	ABC transporter signature motif; other site
331111002694	Walker B; other site
331111002695	D-loop; other site
331111002696	H-loop/switch region; other site
331111002697	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
331111002698	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
331111002699	molybdenum-pterin binding domain; Region: Mop; TIGR00638
331111002700	TOBE domain; Region: TOBE; pfam03459
331111002701	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
331111002702	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
331111002703	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111002704	substrate binding pocket [chemical binding]; other site
331111002705	membrane-bound complex binding site; other site
331111002706	hinge residues; other site
331111002707	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
331111002708	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111002709	putative PBP binding loops; other site
331111002710	ABC-ATPase subunit interface; other site
331111002711	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
331111002712	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111002713	Walker A/P-loop; other site
331111002714	ATP binding site [chemical binding]; other site
331111002715	Q-loop/lid; other site
331111002716	ABC transporter signature motif; other site
331111002717	Walker B; other site
331111002718	D-loop; other site
331111002719	H-loop/switch region; other site
331111002720	molybdenum-pterin binding domain; Region: Mop; TIGR00638
331111002721	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
331111002722	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111002723	motif II; other site
331111002724	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111002725	6-phosphogluconolactonase; Provisional; Region: PRK11028
331111002726	Transcriptional regulator [Transcription]; Region: LysR; COG0583
331111002727	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111002728	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
331111002729	putative dimerization interface [polypeptide binding]; other site
331111002730	PrpF protein; Region: PrpF; pfam04303
331111002731	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
331111002732	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
331111002733	transmembrane helices; other site
331111002734	putative hydratase; Provisional; Region: PRK11413
331111002735	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
331111002736	substrate binding site [chemical binding]; other site
331111002737	ligand binding site [chemical binding]; other site
331111002738	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
331111002739	substrate binding site [chemical binding]; other site
331111002740	acyl-CoA thioesterase; Provisional; Region: PRK10531
331111002741	putative pectinesterase; Region: PLN02432; cl01911
331111002742	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
331111002743	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235
331111002744	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
331111002745	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
331111002746	dimer interface [polypeptide binding]; other site
331111002747	active site
331111002748	Int/Topo IB signature motif; other site
331111002749	DksA-like zinc finger domain containing protein; Region: PHA00080
331111002750	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
331111002751	phage recombination protein Bet; Region: bet_lambda; TIGR01913
331111002752	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
331111002753	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
331111002754	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111002755	non-specific DNA binding site [nucleotide binding]; other site
331111002756	salt bridge; other site
331111002757	Predicted transcriptional regulator [Transcription]; Region: COG2932
331111002758	sequence-specific DNA binding site [nucleotide binding]; other site
331111002759	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
331111002760	Catalytic site [active]
331111002761	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
331111002762	Replication protein P; Region: Phage_lambda_P; pfam06992
331111002763	multidrug efflux protein; Reviewed; Region: emrE; PRK09541
331111002764	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
331111002765	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111002766	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
331111002767	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
331111002768	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111002769	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111002770	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111002771	Transposase; Region: HTH_Tnp_1; pfam01527
331111002772	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111002773	hypothetical protein; Provisional; Region: PRK09741
331111002774	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
331111002775	endodeoxyribonuclease RUS; Reviewed; Region: PRK09786
331111002776	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
331111002777	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
331111002778	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
331111002779	trimer interface [polypeptide binding]; other site
331111002780	eyelet of channel; other site
331111002781	Lysis protein S; Region: Lysis_S; pfam04971
331111002782	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
331111002783	catalytic residues [active]
331111002784	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
331111002785	KilA-N domain; Region: KilA-N; pfam04383
331111002786	ORF11CD3 domain; Region: ORF11CD3; pfam10549
331111002787	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
331111002788	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
331111002789	Phage Tail Collar Domain; Region: Collar; pfam07484
331111002790	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
331111002791	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
331111002792	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111002793	metal binding site [ion binding]; metal-binding site
331111002794	active site
331111002795	I-site; other site
331111002796	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
331111002797	substrate binding site [chemical binding]; other site
331111002798	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
331111002799	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
331111002800	inhibitor-cofactor binding pocket; inhibition site
331111002801	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111002802	catalytic residue [active]
331111002803	biotin synthase; Provisional; Region: PRK15108
331111002804	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111002805	FeS/SAM binding site; other site
331111002806	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
331111002807	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
331111002808	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
331111002809	substrate-cofactor binding pocket; other site
331111002810	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111002811	catalytic residue [active]
331111002812	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
331111002813	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111002814	S-adenosylmethionine binding site [chemical binding]; other site
331111002815	AAA domain; Region: AAA_26; pfam13500
331111002816	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
331111002817	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
331111002818	ADP binding site [chemical binding]; other site
331111002819	excinuclease ABC subunit B; Provisional; Region: PRK05298
331111002820	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
331111002821	ATP binding site [chemical binding]; other site
331111002822	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111002823	nucleotide binding region [chemical binding]; other site
331111002824	ATP-binding site [chemical binding]; other site
331111002825	Ultra-violet resistance protein B; Region: UvrB; pfam12344
331111002826	UvrB/uvrC motif; Region: UVR; pfam02151
331111002827	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
331111002828	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
331111002829	putative substrate binding pocket [chemical binding]; other site
331111002830	dimer interface [polypeptide binding]; other site
331111002831	phosphate binding site [ion binding]; other site
331111002832	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
331111002833	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111002834	FeS/SAM binding site; other site
331111002835	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
331111002836	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
331111002837	MPT binding site; other site
331111002838	trimer interface [polypeptide binding]; other site
331111002839	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
331111002840	trimer interface [polypeptide binding]; other site
331111002841	dimer interface [polypeptide binding]; other site
331111002842	putative active site [active]
331111002843	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
331111002844	MoaE interaction surface [polypeptide binding]; other site
331111002845	MoeB interaction surface [polypeptide binding]; other site
331111002846	thiocarboxylated glycine; other site
331111002847	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
331111002848	MoaE homodimer interface [polypeptide binding]; other site
331111002849	MoaD interaction [polypeptide binding]; other site
331111002850	active site residues [active]
331111002851	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
331111002852	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
331111002853	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
331111002854	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
331111002855	Predicted integral membrane protein [Function unknown]; Region: COG0392
331111002856	cardiolipin synthase 2; Provisional; Region: PRK11263
331111002857	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
331111002858	putative active site [active]
331111002859	catalytic site [active]
331111002860	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
331111002861	putative active site [active]
331111002862	catalytic site [active]
331111002863	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
331111002864	putative catalytic site [active]
331111002865	putative metal binding site [ion binding]; other site
331111002866	putative phosphate binding site [ion binding]; other site
331111002867	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
331111002868	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
331111002869	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
331111002870	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
331111002871	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
331111002872	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
331111002873	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
331111002874	Walker A/P-loop; other site
331111002875	ATP binding site [chemical binding]; other site
331111002876	Q-loop/lid; other site
331111002877	ABC transporter signature motif; other site
331111002878	Walker B; other site
331111002879	D-loop; other site
331111002880	H-loop/switch region; other site
331111002881	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
331111002882	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
331111002883	Walker A/P-loop; other site
331111002884	ATP binding site [chemical binding]; other site
331111002885	Q-loop/lid; other site
331111002886	ABC transporter signature motif; other site
331111002887	Walker B; other site
331111002888	D-loop; other site
331111002889	H-loop/switch region; other site
331111002890	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
331111002891	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
331111002892	HlyD family secretion protein; Region: HlyD_3; pfam13437
331111002893	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
331111002894	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
331111002895	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
331111002896	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
331111002897	ATP binding site [chemical binding]; other site
331111002898	Mg++ binding site [ion binding]; other site
331111002899	motif III; other site
331111002900	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111002901	nucleotide binding region [chemical binding]; other site
331111002902	ATP-binding site [chemical binding]; other site
331111002903	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3236
331111002904	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
331111002905	DEAD_2; Region: DEAD_2; pfam06733
331111002906	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
331111002907	glycosyl transferase family protein; Provisional; Region: PRK08136
331111002908	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
331111002909	putative dehydrogenase; Provisional; Region: PRK10098
331111002910	hypothetical protein; Provisional; Region: PRK10259
331111002911	hypothetical protein; Provisional; Region: PRK11019
331111002912	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
331111002913	catecholate siderophore receptor Fiu; Provisional; Region: PRK09840
331111002914	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
331111002915	N-terminal plug; other site
331111002916	ligand-binding site [chemical binding]; other site
331111002917	hypothetical protein; Provisional; Region: PRK10259
331111002918	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
331111002919	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
331111002920	putative mechanosensitive channel protein; Provisional; Region: PRK11465
331111002921	Mechanosensitive ion channel; Region: MS_channel; pfam00924
331111002922	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
331111002923	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
331111002924	Walker A/P-loop; other site
331111002925	ATP binding site [chemical binding]; other site
331111002926	Q-loop/lid; other site
331111002927	ABC transporter signature motif; other site
331111002928	Walker B; other site
331111002929	D-loop; other site
331111002930	H-loop/switch region; other site
331111002931	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
331111002932	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111002933	dimer interface [polypeptide binding]; other site
331111002934	conserved gate region; other site
331111002935	putative PBP binding loops; other site
331111002936	ABC-ATPase subunit interface; other site
331111002937	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
331111002938	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111002939	substrate binding pocket [chemical binding]; other site
331111002940	membrane-bound complex binding site; other site
331111002941	hinge residues; other site
331111002942	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
331111002943	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
331111002944	dimerization interface [polypeptide binding]; other site
331111002945	DPS ferroxidase diiron center [ion binding]; other site
331111002946	ion pore; other site
331111002947	threonine and homoserine efflux system; Provisional; Region: PRK10532
331111002948	EamA-like transporter family; Region: EamA; pfam00892
331111002949	outer membrane protein X; Provisional; Region: ompX; PRK09408
331111002950	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
331111002951	Sulfatase; Region: Sulfatase; pfam00884
331111002952	manganese transport regulator MntR; Provisional; Region: PRK11050
331111002953	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
331111002954	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
331111002955	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
331111002956	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
331111002957	transmembrane helices; other site
331111002958	L,D-transpeptidase; Provisional; Region: PRK10260
331111002959	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
331111002960	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
331111002961	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111002962	Walker A/P-loop; other site
331111002963	ATP binding site [chemical binding]; other site
331111002964	Q-loop/lid; other site
331111002965	ABC transporter signature motif; other site
331111002966	Walker B; other site
331111002967	D-loop; other site
331111002968	H-loop/switch region; other site
331111002969	ABC transporter; Region: ABC_tran_2; pfam12848
331111002970	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
331111002971	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
331111002972	Transposase; Region: DEDD_Tnp_IS110; pfam01548
331111002973	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
331111002974	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
331111002975	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
331111002976	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111002977	active site
331111002978	motif I; other site
331111002979	motif II; other site
331111002980	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111002981	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
331111002982	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
331111002983	dimer interface [polypeptide binding]; other site
331111002984	active site
331111002985	glycine loop; other site
331111002986	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
331111002987	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
331111002988	active site
331111002989	intersubunit interactions; other site
331111002990	catalytic residue [active]
331111002991	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
331111002992	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
331111002993	ATP binding site [chemical binding]; other site
331111002994	substrate interface [chemical binding]; other site
331111002995	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
331111002996	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
331111002997	dimer interface [polypeptide binding]; other site
331111002998	putative functional site; other site
331111002999	putative MPT binding site; other site
331111003000	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
331111003001	catalytic nucleophile [active]
331111003002	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
331111003003	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
331111003004	Walker A/P-loop; other site
331111003005	ATP binding site [chemical binding]; other site
331111003006	Q-loop/lid; other site
331111003007	ABC transporter signature motif; other site
331111003008	Walker B; other site
331111003009	D-loop; other site
331111003010	H-loop/switch region; other site
331111003011	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
331111003012	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
331111003013	Walker A/P-loop; other site
331111003014	ATP binding site [chemical binding]; other site
331111003015	Q-loop/lid; other site
331111003016	ABC transporter signature motif; other site
331111003017	Walker B; other site
331111003018	D-loop; other site
331111003019	H-loop/switch region; other site
331111003020	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
331111003021	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
331111003022	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
331111003023	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
331111003024	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111003025	dimer interface [polypeptide binding]; other site
331111003026	conserved gate region; other site
331111003027	putative PBP binding loops; other site
331111003028	ABC-ATPase subunit interface; other site
331111003029	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
331111003030	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
331111003031	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111003032	dimer interface [polypeptide binding]; other site
331111003033	conserved gate region; other site
331111003034	putative PBP binding loops; other site
331111003035	ABC-ATPase subunit interface; other site
331111003036	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
331111003037	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
331111003038	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111003039	metal binding site [ion binding]; metal-binding site
331111003040	active site
331111003041	I-site; other site
331111003042	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
331111003043	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
331111003044	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111003045	FeS/SAM binding site; other site
331111003046	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
331111003047	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
331111003048	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
331111003049	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
331111003050	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
331111003051	putative C-terminal domain interface [polypeptide binding]; other site
331111003052	putative GSH binding site (G-site) [chemical binding]; other site
331111003053	putative dimer interface [polypeptide binding]; other site
331111003054	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
331111003055	N-terminal domain interface [polypeptide binding]; other site
331111003056	dimer interface [polypeptide binding]; other site
331111003057	substrate binding pocket (H-site) [chemical binding]; other site
331111003058	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
331111003059	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
331111003060	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
331111003061	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
331111003062	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
331111003063	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
331111003064	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
331111003065	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
331111003066	active site
331111003067	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
331111003068	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111003069	putative substrate translocation pore; other site
331111003070	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
331111003071	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111003072	active site
331111003073	motif I; other site
331111003074	motif II; other site
331111003075	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111003076	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
331111003077	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111003078	putative substrate translocation pore; other site
331111003079	Major Facilitator Superfamily; Region: MFS_1; pfam07690
331111003080	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
331111003081	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
331111003082	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
331111003083	putative transporter; Provisional; Region: PRK04972
331111003084	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
331111003085	TrkA-C domain; Region: TrkA_C; pfam02080
331111003086	TrkA-C domain; Region: TrkA_C; pfam02080
331111003087	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
331111003088	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
331111003089	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
331111003090	GSH binding site [chemical binding]; other site
331111003091	catalytic residues [active]
331111003092	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
331111003093	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
331111003094	dimer interface [polypeptide binding]; other site
331111003095	FMN binding site [chemical binding]; other site
331111003096	NADPH bind site [chemical binding]; other site
331111003097	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
331111003098	RimK-like ATP-grasp domain; Region: RimK; pfam08443
331111003099	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
331111003100	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
331111003101	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
331111003102	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
331111003103	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111003104	Walker A/P-loop; other site
331111003105	ATP binding site [chemical binding]; other site
331111003106	Q-loop/lid; other site
331111003107	ABC transporter signature motif; other site
331111003108	Walker B; other site
331111003109	D-loop; other site
331111003110	H-loop/switch region; other site
331111003111	TOBE domain; Region: TOBE_2; pfam08402
331111003112	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
331111003113	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111003114	dimer interface [polypeptide binding]; other site
331111003115	conserved gate region; other site
331111003116	putative PBP binding loops; other site
331111003117	ABC-ATPase subunit interface; other site
331111003118	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
331111003119	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111003120	dimer interface [polypeptide binding]; other site
331111003121	conserved gate region; other site
331111003122	putative PBP binding loops; other site
331111003123	ABC-ATPase subunit interface; other site
331111003124	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
331111003125	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
331111003126	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111003127	S-adenosylmethionine binding site [chemical binding]; other site
331111003128	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
331111003129	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111003130	substrate binding pocket [chemical binding]; other site
331111003131	membrane-bound complex binding site; other site
331111003132	hinge residues; other site
331111003133	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111003134	dimer interface [polypeptide binding]; other site
331111003135	conserved gate region; other site
331111003136	putative PBP binding loops; other site
331111003137	ABC-ATPase subunit interface; other site
331111003138	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
331111003139	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111003140	dimer interface [polypeptide binding]; other site
331111003141	conserved gate region; other site
331111003142	putative PBP binding loops; other site
331111003143	ABC-ATPase subunit interface; other site
331111003144	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
331111003145	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111003146	substrate binding pocket [chemical binding]; other site
331111003147	membrane-bound complex binding site; other site
331111003148	hinge residues; other site
331111003149	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
331111003150	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111003151	Walker A/P-loop; other site
331111003152	ATP binding site [chemical binding]; other site
331111003153	Q-loop/lid; other site
331111003154	ABC transporter signature motif; other site
331111003155	Walker B; other site
331111003156	D-loop; other site
331111003157	H-loop/switch region; other site
331111003158	putative lipoprotein; Provisional; Region: PRK10533
331111003159	hypothetical protein; Provisional; Region: PRK02877
331111003160	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
331111003161	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
331111003162	amidase catalytic site [active]
331111003163	Zn binding residues [ion binding]; other site
331111003164	substrate binding site [chemical binding]; other site
331111003165	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
331111003166	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
331111003167	NAD(P) binding site [chemical binding]; other site
331111003168	active site
331111003169	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
331111003170	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
331111003171	putative NAD(P) binding site [chemical binding]; other site
331111003172	putative active site [active]
331111003173	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
331111003174	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
331111003175	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
331111003176	tetramer interface [polypeptide binding]; other site
331111003177	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111003178	catalytic residue [active]
331111003179	pyruvate dehydrogenase; Provisional; Region: PRK09124
331111003180	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
331111003181	PYR/PP interface [polypeptide binding]; other site
331111003182	dimer interface [polypeptide binding]; other site
331111003183	tetramer interface [polypeptide binding]; other site
331111003184	TPP binding site [chemical binding]; other site
331111003185	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
331111003186	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
331111003187	TPP-binding site [chemical binding]; other site
331111003188	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
331111003189	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
331111003190	FAD binding pocket [chemical binding]; other site
331111003191	FAD binding motif [chemical binding]; other site
331111003192	phosphate binding motif [ion binding]; other site
331111003193	beta-alpha-beta structure motif; other site
331111003194	NAD binding pocket [chemical binding]; other site
331111003195	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
331111003196	catalytic loop [active]
331111003197	iron binding site [ion binding]; other site
331111003198	hybrid cluster protein; Provisional; Region: PRK05290
331111003199	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
331111003200	ACS interaction site; other site
331111003201	CODH interaction site; other site
331111003202	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
331111003203	hybrid metal cluster; other site
331111003204	Predicted membrane protein [Function unknown]; Region: COG2431
331111003205	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
331111003206	amphipathic channel; other site
331111003207	Asn-Pro-Ala signature motifs; other site
331111003208	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
331111003209	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
331111003210	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
331111003211	putative active site [active]
331111003212	putative metal-binding site [ion binding]; other site
331111003213	Protein of unknown function (DUF535); Region: DUF535; pfam04393
331111003214	macrolide transporter subunit MacA; Provisional; Region: PRK11578
331111003215	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
331111003216	HlyD family secretion protein; Region: HlyD_3; pfam13437
331111003217	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
331111003218	DNA-binding site [nucleotide binding]; DNA binding site
331111003219	RNA-binding motif; other site
331111003220	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
331111003221	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
331111003222	Clp amino terminal domain; Region: Clp_N; pfam02861
331111003223	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111003224	Walker A motif; other site
331111003225	ATP binding site [chemical binding]; other site
331111003226	Walker B motif; other site
331111003227	arginine finger; other site
331111003228	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111003229	Walker A motif; other site
331111003230	ATP binding site [chemical binding]; other site
331111003231	Walker B motif; other site
331111003232	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
331111003233	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
331111003234	rRNA binding site [nucleotide binding]; other site
331111003235	predicted 30S ribosome binding site; other site
331111003236	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
331111003237	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
331111003238	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
331111003239	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
331111003240	Walker A/P-loop; other site
331111003241	ATP binding site [chemical binding]; other site
331111003242	Q-loop/lid; other site
331111003243	ABC transporter signature motif; other site
331111003244	Walker B; other site
331111003245	D-loop; other site
331111003246	H-loop/switch region; other site
331111003247	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
331111003248	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
331111003249	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111003250	Walker A/P-loop; other site
331111003251	ATP binding site [chemical binding]; other site
331111003252	Q-loop/lid; other site
331111003253	ABC transporter signature motif; other site
331111003254	Walker B; other site
331111003255	D-loop; other site
331111003256	H-loop/switch region; other site
331111003257	thioredoxin reductase; Provisional; Region: PRK10262
331111003258	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
331111003259	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111003260	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
331111003261	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
331111003262	putative DNA binding site [nucleotide binding]; other site
331111003263	putative Zn2+ binding site [ion binding]; other site
331111003264	AsnC family; Region: AsnC_trans_reg; pfam01037
331111003265	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
331111003266	DNA translocase FtsK; Provisional; Region: PRK10263
331111003267	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
331111003268	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
331111003269	periplasmic chaperone LolA; Region: lolA; TIGR00547
331111003270	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
331111003271	recombination factor protein RarA; Reviewed; Region: PRK13342
331111003272	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111003273	Walker A motif; other site
331111003274	ATP binding site [chemical binding]; other site
331111003275	Walker B motif; other site
331111003276	arginine finger; other site
331111003277	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
331111003278	seryl-tRNA synthetase; Provisional; Region: PRK05431
331111003279	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
331111003280	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
331111003281	dimer interface [polypeptide binding]; other site
331111003282	active site
331111003283	motif 1; other site
331111003284	motif 2; other site
331111003285	motif 3; other site
331111003286	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
331111003287	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
331111003288	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
331111003289	putative [Fe4-S4] binding site [ion binding]; other site
331111003290	putative molybdopterin cofactor binding site [chemical binding]; other site
331111003291	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
331111003292	putative molybdopterin cofactor binding site; other site
331111003293	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
331111003294	4Fe-4S binding domain; Region: Fer4; pfam00037
331111003295	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
331111003296	Isochorismatase family; Region: Isochorismatase; pfam00857
331111003297	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
331111003298	catalytic triad [active]
331111003299	dimer interface [polypeptide binding]; other site
331111003300	conserved cis-peptide bond; other site
331111003301	putative MFS family transporter protein; Provisional; Region: PRK03633
331111003302	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111003303	putative substrate translocation pore; other site
331111003304	Amino acid permease; Region: AA_permease_2; pfam13520
331111003305	Transcriptional regulator [Transcription]; Region: LysR; COG0583
331111003306	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111003307	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
331111003308	putative effector binding pocket; other site
331111003309	putative dimerization interface [polypeptide binding]; other site
331111003310	hypothetical protein; Provisional; Region: PRK09739
331111003311	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
331111003312	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
331111003313	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111003314	FeS/SAM binding site; other site
331111003315	integrase; Provisional; Region: int; PHA02601
331111003316	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
331111003317	active site
331111003318	DNA binding site [nucleotide binding]
331111003319	Int/Topo IB signature motif; other site
331111003320	Regulatory phage protein cox; Region: Phage_Cox; pfam10743
331111003321	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
331111003322	DksA-like zinc finger domain containing protein; Region: PHA00080
331111003323	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
331111003324	AAA domain; Region: AAA_21; pfam13304
331111003325	Phage portal protein; Region: Phage_portal; pfam04860
331111003326	Phage-related protein [Function unknown]; Region: COG4695; cl01923
331111003327	Phage-related tail protein [Function unknown]; Region: COG5283
331111003328	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
331111003329	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
331111003330	Helix-turn-helix domain; Region: HTH_38; pfam13936
331111003331	Integrase core domain; Region: rve; pfam00665
331111003332	Integrase core domain; Region: rve_3; cl15866
331111003333	transposase/IS protein; Provisional; Region: PRK09183
331111003334	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111003335	Walker A motif; other site
331111003336	ATP binding site [chemical binding]; other site
331111003337	Walker B motif; other site
331111003338	arginine finger; other site
331111003339	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
331111003340	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
331111003341	tail protein; Provisional; Region: D; PHA02561
331111003342	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
331111003343	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
331111003344	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
331111003345	Pyruvate formate lyase 1; Region: PFL1; cd01678
331111003346	coenzyme A binding site [chemical binding]; other site
331111003347	active site
331111003348	catalytic residues [active]
331111003349	glycine loop; other site
331111003350	formate transporter; Provisional; Region: PRK10805
331111003351	uncharacterized domain; Region: TIGR00702
331111003352	YcaO-like family; Region: YcaO; pfam02624
331111003353	Predicted membrane protein [Function unknown]; Region: COG2323
331111003354	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
331111003355	homodimer interface [polypeptide binding]; other site
331111003356	substrate-cofactor binding pocket; other site
331111003357	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111003358	catalytic residue [active]
331111003359	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
331111003360	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
331111003361	hinge; other site
331111003362	active site
331111003363	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
331111003364	cytidylate kinase; Provisional; Region: cmk; PRK00023
331111003365	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
331111003366	CMP-binding site; other site
331111003367	The sites determining sugar specificity; other site
331111003368	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
331111003369	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
331111003370	RNA binding site [nucleotide binding]; other site
331111003371	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
331111003372	RNA binding site [nucleotide binding]; other site
331111003373	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
331111003374	RNA binding site [nucleotide binding]; other site
331111003375	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
331111003376	RNA binding site [nucleotide binding]; other site
331111003377	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
331111003378	RNA binding site [nucleotide binding]; other site
331111003379	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
331111003380	IHF dimer interface [polypeptide binding]; other site
331111003381	IHF - DNA interface [nucleotide binding]; other site
331111003382	ComEC family competence protein; Provisional; Region: PRK11539
331111003383	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
331111003384	ComEC/Rec2-related protein; Region: ComEC_N-term; TIGR00360
331111003385	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
331111003386	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
331111003387	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
331111003388	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
331111003389	Walker A/P-loop; other site
331111003390	ATP binding site [chemical binding]; other site
331111003391	Q-loop/lid; other site
331111003392	ABC transporter signature motif; other site
331111003393	Walker B; other site
331111003394	D-loop; other site
331111003395	H-loop/switch region; other site
331111003396	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
331111003397	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
331111003398	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
331111003399	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
331111003400	hypothetical protein; Provisional; Region: PRK11827
331111003401	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
331111003402	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
331111003403	Ligand binding site; other site
331111003404	oligomer interface; other site
331111003405	hypothetical protein; Provisional; Region: PRK10593
331111003406	Uncharacterized conserved protein [Function unknown]; Region: COG1434
331111003407	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
331111003408	putative active site [active]
331111003409	Methyltransferase domain; Region: Methyltransf_31; pfam13847
331111003410	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111003411	S-adenosylmethionine binding site [chemical binding]; other site
331111003412	condesin subunit F; Provisional; Region: PRK05260
331111003413	condesin subunit E; Provisional; Region: PRK05256
331111003414	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
331111003415	MukB N-terminal; Region: MukB; pfam04310
331111003416	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
331111003417	murein L,D-transpeptidase; Provisional; Region: PRK10594
331111003418	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
331111003419	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
331111003420	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
331111003421	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
331111003422	Peptidase M15; Region: Peptidase_M15_3; cl01194
331111003423	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
331111003424	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
331111003425	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
331111003426	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111003427	homodimer interface [polypeptide binding]; other site
331111003428	catalytic residue [active]
331111003429	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
331111003430	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
331111003431	trimer interface [polypeptide binding]; other site
331111003432	eyelet of channel; other site
331111003433	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
331111003434	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
331111003435	putative dimer interface [polypeptide binding]; other site
331111003436	putative anticodon binding site; other site
331111003437	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
331111003438	homodimer interface [polypeptide binding]; other site
331111003439	motif 1; other site
331111003440	motif 2; other site
331111003441	active site
331111003442	motif 3; other site
331111003443	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
331111003444	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
331111003445	active site
331111003446	aminopeptidase N; Provisional; Region: pepN; PRK14015
331111003447	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
331111003448	active site
331111003449	Zn binding site [ion binding]; other site
331111003450	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
331111003451	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
331111003452	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
331111003453	Walker A/P-loop; other site
331111003454	ATP binding site [chemical binding]; other site
331111003455	Q-loop/lid; other site
331111003456	ABC transporter signature motif; other site
331111003457	Walker B; other site
331111003458	D-loop; other site
331111003459	H-loop/switch region; other site
331111003460	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
331111003461	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111003462	dimer interface [polypeptide binding]; other site
331111003463	conserved gate region; other site
331111003464	putative PBP binding loops; other site
331111003465	ABC-ATPase subunit interface; other site
331111003466	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
331111003467	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
331111003468	active site
331111003469	dimer interface [polypeptide binding]; other site
331111003470	non-prolyl cis peptide bond; other site
331111003471	insertion regions; other site
331111003472	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
331111003473	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
331111003474	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
331111003475	Tail fiber protein gp37 C terminal; Region: gp37_C; pfam12604
331111003476	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; cl01542
331111003477	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
331111003478	Phage protein GP46; Region: GP46; pfam07409
331111003479	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
331111003480	Bacteriophage Mu Gp45 protein; Region: Phage_Mu_Gp45; pfam06890
331111003481	Mu-like prophage tail protein gpP [General function prediction only]; Region: COG4379
331111003482	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
331111003483	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
331111003484	Mu DNA binding, I gamma subdomain; Region: HTH_Tnp_Mu_2; pfam09039
331111003485	Bacteriophage Mu transposase; Region: DDE_2; pfam02914
331111003486	Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299
331111003487	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
331111003488	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111003489	substrate binding pocket [chemical binding]; other site
331111003490	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
331111003491	membrane-bound complex binding site; other site
331111003492	hinge residues; other site
331111003493	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
331111003494	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
331111003495	Fimbrial protein; Region: Fimbrial; cl01416
331111003496	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
331111003497	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
331111003498	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
331111003499	outer membrane usher protein; Provisional; Region: PRK15193
331111003500	PapC N-terminal domain; Region: PapC_N; pfam13954
331111003501	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
331111003502	PapC C-terminal domain; Region: PapC_C; pfam13953
331111003503	Fimbrial protein; Region: Fimbrial; cl01416
331111003504	Fimbrial protein; Region: Fimbrial; cl01416
331111003505	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
331111003506	putativi pili assembly chaperone; Provisional; Region: PRK11385
331111003507	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
331111003508	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
331111003509	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
331111003510	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
331111003511	quinone interaction residues [chemical binding]; other site
331111003512	active site
331111003513	catalytic residues [active]
331111003514	FMN binding site [chemical binding]; other site
331111003515	substrate binding site [chemical binding]; other site
331111003516	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
331111003517	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
331111003518	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
331111003519	MOSC domain; Region: MOSC; pfam03473
331111003520	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
331111003521	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
331111003522	catalytic loop [active]
331111003523	iron binding site [ion binding]; other site
331111003524	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
331111003525	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
331111003526	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
331111003527	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111003528	S-adenosylmethionine binding site [chemical binding]; other site
331111003529	ABC transporter ATPase component; Reviewed; Region: PRK11147
331111003530	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111003531	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111003532	Walker A/P-loop; other site
331111003533	Walker A/P-loop; other site
331111003534	ATP binding site [chemical binding]; other site
331111003535	ATP binding site [chemical binding]; other site
331111003536	Q-loop/lid; other site
331111003537	Q-loop/lid; other site
331111003538	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
331111003539	ABC transporter signature motif; other site
331111003540	Walker B; other site
331111003541	D-loop; other site
331111003542	ABC transporter; Region: ABC_tran_2; pfam12848
331111003543	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
331111003544	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
331111003545	Paraquat-inducible protein A; Region: PqiA; pfam04403
331111003546	Paraquat-inducible protein A; Region: PqiA; pfam04403
331111003547	paraquat-inducible protein B; Provisional; Region: PRK10807
331111003548	mce related protein; Region: MCE; pfam02470
331111003549	mce related protein; Region: MCE; pfam02470
331111003550	mce related protein; Region: MCE; pfam02470
331111003551	DASH complex subunit Duo1; Region: DASH_Duo1; pfam08651
331111003552	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
331111003553	Protein of unknown function (DUF330); Region: DUF330; pfam03886
331111003554	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
331111003555	active site 1 [active]
331111003556	dimer interface [polypeptide binding]; other site
331111003557	active site 2 [active]
331111003558	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
331111003559	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
331111003560	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
331111003561	outer membrane protein A; Reviewed; Region: PRK10808
331111003562	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
331111003563	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
331111003564	ligand binding site [chemical binding]; other site
331111003565	cell division inhibitor SulA; Region: sula; TIGR00623
331111003566	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
331111003567	TfoX C-terminal domain; Region: TfoX_C; pfam04994
331111003568	TIGR01666 family membrane protein; Region: YCCS
331111003569	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
331111003570	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
331111003571	Predicted membrane protein [Function unknown]; Region: COG3304
331111003572	Domain of unknown function (DUF307); Region: DUF307; pfam03733
331111003573	Domain of unknown function (DUF307); Region: DUF307; pfam03733
331111003574	DNA helicase IV; Provisional; Region: helD; PRK11054
331111003575	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
331111003576	Part of AAA domain; Region: AAA_19; pfam13245
331111003577	Family description; Region: UvrD_C_2; pfam13538
331111003578	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
331111003579	active site
331111003580	dimer interfaces [polypeptide binding]; other site
331111003581	catalytic residues [active]
331111003582	hypothetical protein; Provisional; Region: PRK03641
331111003583	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
331111003584	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
331111003585	heat shock protein HspQ; Provisional; Region: PRK14129
331111003586	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
331111003587	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
331111003588	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
331111003589	putative RNA binding site [nucleotide binding]; other site
331111003590	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111003591	S-adenosylmethionine binding site [chemical binding]; other site
331111003592	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
331111003593	sulfur transfer protein TusE; Provisional; Region: PRK11508
331111003594	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
331111003595	YccA-like proteins; Region: YccA_like; cd10433
331111003596	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
331111003597	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
331111003598	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
331111003599	hydrogenase 1 large subunit; Provisional; Region: PRK10170
331111003600	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
331111003601	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
331111003602	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
331111003603	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
331111003604	putative substrate-binding site; other site
331111003605	nickel binding site [ion binding]; other site
331111003606	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
331111003607	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
331111003608	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
331111003609	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
331111003610	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
331111003611	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
331111003612	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
331111003613	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
331111003614	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
331111003615	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
331111003616	catalytic core [active]
331111003617	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
331111003618	cryptic autophosphorylating protein tyrosine kinase Etk; Provisional; Region: PRK09841
331111003619	Chain length determinant protein; Region: Wzz; pfam02706
331111003620	Chain length determinant protein; Region: Wzz; cl15801
331111003621	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
331111003622	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
331111003623	Nucleotide binding site [chemical binding]; other site
331111003624	Low molecular weight phosphatase family; Region: LMWPc; cd00115
331111003625	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
331111003626	active site
331111003627	polysaccharide export protein Wza; Provisional; Region: PRK15078
331111003628	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
331111003629	SLBB domain; Region: SLBB; pfam10531
331111003630	SLBB domain; Region: SLBB; pfam10531
331111003631	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
331111003632	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
331111003633	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
331111003634	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
331111003635	DNA-binding site [nucleotide binding]; DNA binding site
331111003636	RNA-binding motif; other site
331111003637	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
331111003638	DNA-binding site [nucleotide binding]; DNA binding site
331111003639	RNA-binding motif; other site
331111003640	GnsA/GnsB family; Region: GnsAB; pfam08178
331111003641	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
331111003642	4Fe-4S binding domain; Region: Fer4_5; pfam12801
331111003643	4Fe-4S binding domain; Region: Fer4_5; pfam12801
331111003644	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
331111003645	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
331111003646	HAMP domain; Region: HAMP; pfam00672
331111003647	dimerization interface [polypeptide binding]; other site
331111003648	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111003649	dimer interface [polypeptide binding]; other site
331111003650	phosphorylation site [posttranslational modification]
331111003651	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111003652	ATP binding site [chemical binding]; other site
331111003653	Mg2+ binding site [ion binding]; other site
331111003654	G-X-G motif; other site
331111003655	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111003656	active site
331111003657	phosphorylation site [posttranslational modification]
331111003658	intermolecular recognition site; other site
331111003659	dimerization interface [polypeptide binding]; other site
331111003660	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
331111003661	putative binding surface; other site
331111003662	active site
331111003663	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
331111003664	TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria; Region: PBP1_TorT-like; cd06306
331111003665	putative ligand binding site [chemical binding]; other site
331111003666	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
331111003667	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111003668	active site
331111003669	phosphorylation site [posttranslational modification]
331111003670	intermolecular recognition site; other site
331111003671	dimerization interface [polypeptide binding]; other site
331111003672	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
331111003673	DNA binding site [nucleotide binding]
331111003674	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
331111003675	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
331111003676	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
331111003677	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
331111003678	molybdopterin cofactor binding site [chemical binding]; other site
331111003679	substrate binding site [chemical binding]; other site
331111003680	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
331111003681	molybdopterin cofactor binding site; other site
331111003682	chaperone protein TorD; Validated; Region: torD; PRK04976
331111003683	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
331111003684	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
331111003685	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
331111003686	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
331111003687	HSP70 interaction site [polypeptide binding]; other site
331111003688	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
331111003689	substrate binding site [polypeptide binding]; other site
331111003690	dimer interface [polypeptide binding]; other site
331111003691	hypothetical protein; Provisional; Region: PRK09784
331111003692	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
331111003693	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
331111003694	catalytic core [active]
331111003695	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
331111003696	hypothetical protein; Provisional; Region: PRK10174
331111003697	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
331111003698	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
331111003699	General stress protein [General function prediction only]; Region: GsiB; COG3729
331111003700	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
331111003701	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
331111003702	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
331111003703	putative FMN binding site [chemical binding]; other site
331111003704	pyrimidine utilization protein D; Region: RutD; TIGR03611
331111003705	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
331111003706	homotrimer interaction site [polypeptide binding]; other site
331111003707	putative active site [active]
331111003708	Isochorismatase family; Region: Isochorismatase; pfam00857
331111003709	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
331111003710	catalytic triad [active]
331111003711	conserved cis-peptide bond; other site
331111003712	pyrimidine utilization protein A; Region: RutA; TIGR03612
331111003713	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
331111003714	active site
331111003715	dimer interface [polypeptide binding]; other site
331111003716	non-prolyl cis peptide bond; other site
331111003717	insertion regions; other site
331111003718	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
331111003719	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
331111003720	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
331111003721	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
331111003722	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
331111003723	Predicted transcriptional regulator [Transcription]; Region: COG3905
331111003724	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
331111003725	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
331111003726	Glutamate binding site [chemical binding]; other site
331111003727	NAD binding site [chemical binding]; other site
331111003728	catalytic residues [active]
331111003729	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
331111003730	Na binding site [ion binding]; other site
331111003731	FTR1 family protein; Region: TIGR00145
331111003732	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
331111003733	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
331111003734	Imelysin; Region: Peptidase_M75; pfam09375
331111003735	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
331111003736	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
331111003737	putative PGA biosynthesis protein; Provisional; Region: pgaD; PRK14585
331111003738	N-glycosyltransferase; Provisional; Region: PRK11204
331111003739	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
331111003740	DXD motif; other site
331111003741	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
331111003742	outer membrane N-deacetylase; Provisional; Region: pgaB; PRK14582
331111003743	N-terminal putative catalytic polysaccharide deacetylase domain of bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, and similar proteins; Region: CE4_PgaB_5s; cd10964
331111003744	putative active site [active]
331111003745	putative metal binding site [ion binding]; other site
331111003746	outer membrane protein PgaA; Provisional; Region: pgaA; PRK10049
331111003747	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
331111003748	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111003749	metal binding site [ion binding]; metal-binding site
331111003750	active site
331111003751	I-site; other site
331111003752	putative transposase OrfB; Reviewed; Region: PHA02517
331111003753	HTH-like domain; Region: HTH_21; pfam13276
331111003754	Integrase core domain; Region: rve; pfam00665
331111003755	Integrase core domain; Region: rve_2; pfam13333
331111003756	Transposase; Region: HTH_Tnp_1; cl17663
331111003757	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111003758	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
331111003759	putative hydrolase; Validated; Region: PRK09248
331111003760	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
331111003761	active site
331111003762	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
331111003763	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
331111003764	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
331111003765	curli assembly protein CsgF; Provisional; Region: PRK10050
331111003766	curli assembly protein CsgE; Provisional; Region: PRK10386
331111003767	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
331111003768	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111003769	DNA binding residues [nucleotide binding]
331111003770	dimerization interface [polypeptide binding]; other site
331111003771	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
331111003772	Curlin associated repeat; Region: Curlin_rpt; pfam07012
331111003773	Curlin associated repeat; Region: Curlin_rpt; pfam07012
331111003774	major curlin subunit; Provisional; Region: csgA; PRK10051
331111003775	Curlin associated repeat; Region: Curlin_rpt; pfam07012
331111003776	Curlin associated repeat; Region: Curlin_rpt; pfam07012
331111003777	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
331111003778	Fimbrial protein; Region: Fimbrial; cl01416
331111003779	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
331111003780	putative ADP-ribose binding site [chemical binding]; other site
331111003781	putative active site [active]
331111003782	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
331111003783	PLD-like domain; Region: PLDc_2; pfam13091
331111003784	putative active site [active]
331111003785	catalytic site [active]
331111003786	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
331111003787	PLD-like domain; Region: PLDc_2; pfam13091
331111003788	putative active site [active]
331111003789	catalytic site [active]
331111003790	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
331111003791	Acyltransferase family; Region: Acyl_transf_3; pfam01757
331111003792	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
331111003793	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
331111003794	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
331111003795	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
331111003796	Ligand binding site; other site
331111003797	DXD motif; other site
331111003798	lipoprotein; Provisional; Region: PRK10175
331111003799	secY/secA suppressor protein; Provisional; Region: PRK11467
331111003800	drug efflux system protein MdtG; Provisional; Region: PRK09874
331111003801	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111003802	putative substrate translocation pore; other site
331111003803	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
331111003804	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
331111003805	putative acyl-acceptor binding pocket; other site
331111003806	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
331111003807	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
331111003808	active site residue [active]
331111003809	hypothetical protein; Provisional; Region: PRK03757
331111003810	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
331111003811	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
331111003812	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
331111003813	hydroxyglutarate oxidase; Provisional; Region: PRK11728
331111003814	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
331111003815	DNA damage-inducible protein I; Provisional; Region: PRK10597
331111003816	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
331111003817	active site
331111003818	substrate binding pocket [chemical binding]; other site
331111003819	dimer interface [polypeptide binding]; other site
331111003820	lipoprotein; Provisional; Region: PRK10598
331111003821	glutaredoxin 2; Provisional; Region: PRK10387
331111003822	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
331111003823	C-terminal domain interface [polypeptide binding]; other site
331111003824	GSH binding site (G-site) [chemical binding]; other site
331111003825	catalytic residues [active]
331111003826	putative dimer interface [polypeptide binding]; other site
331111003827	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
331111003828	N-terminal domain interface [polypeptide binding]; other site
331111003829	multidrug resistance protein MdtH; Provisional; Region: PRK11646
331111003830	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111003831	putative substrate translocation pore; other site
331111003832	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
331111003833	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
331111003834	hypothetical protein; Provisional; Region: PRK11239
331111003835	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
331111003836	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
331111003837	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
331111003838	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
331111003839	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
331111003840	MviN-like protein; Region: MVIN; pfam03023
331111003841	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
331111003842	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
331111003843	Flagellar basal body P-ring biosynthesis protein [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FlgA; COG1261
331111003844	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
331111003845	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
331111003846	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
331111003847	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
331111003848	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
331111003849	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
331111003850	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
331111003851	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
331111003852	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
331111003853	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
331111003854	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
331111003855	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
331111003856	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
331111003857	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
331111003858	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
331111003859	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
331111003860	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
331111003861	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
331111003862	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
331111003863	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
331111003864	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
331111003865	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
331111003866	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
331111003867	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
331111003868	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
331111003869	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
331111003870	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
331111003871	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
331111003872	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
331111003873	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
331111003874	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
331111003875	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
331111003876	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
331111003877	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
331111003878	homodimer interface [polypeptide binding]; other site
331111003879	oligonucleotide binding site [chemical binding]; other site
331111003880	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
331111003881	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
331111003882	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
331111003883	RNA binding surface [nucleotide binding]; other site
331111003884	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
331111003885	active site
331111003886	Maf-like protein; Region: Maf; pfam02545
331111003887	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
331111003888	active site
331111003889	dimer interface [polypeptide binding]; other site
331111003890	hypothetical protein; Provisional; Region: PRK11193
331111003891	putative phosphate acyltransferase; Provisional; Region: PRK05331
331111003892	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
331111003893	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
331111003894	dimer interface [polypeptide binding]; other site
331111003895	active site
331111003896	CoA binding pocket [chemical binding]; other site
331111003897	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
331111003898	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
331111003899	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
331111003900	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
331111003901	NAD(P) binding site [chemical binding]; other site
331111003902	homotetramer interface [polypeptide binding]; other site
331111003903	homodimer interface [polypeptide binding]; other site
331111003904	active site
331111003905	acyl carrier protein; Provisional; Region: acpP; PRK00982
331111003906	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
331111003907	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
331111003908	dimer interface [polypeptide binding]; other site
331111003909	active site
331111003910	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
331111003911	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
331111003912	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111003913	catalytic residue [active]
331111003914	conserved hypothetical protein, YceG family; Region: TIGR00247
331111003915	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
331111003916	dimerization interface [polypeptide binding]; other site
331111003917	thymidylate kinase; Validated; Region: tmk; PRK00698
331111003918	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
331111003919	TMP-binding site; other site
331111003920	ATP-binding site [chemical binding]; other site
331111003921	DNA polymerase III subunit delta'; Validated; Region: PRK07993
331111003922	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
331111003923	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
331111003924	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
331111003925	active site
331111003926	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
331111003927	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
331111003928	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
331111003929	active site turn [active]
331111003930	phosphorylation site [posttranslational modification]
331111003931	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
331111003932	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
331111003933	N-terminal plug; other site
331111003934	ligand-binding site [chemical binding]; other site
331111003935	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
331111003936	nucleotide binding site/active site [active]
331111003937	HIT family signature motif; other site
331111003938	catalytic residue [active]
331111003939	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
331111003940	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
331111003941	putative dimer interface [polypeptide binding]; other site
331111003942	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
331111003943	thiamine kinase; Region: ycfN_thiK; TIGR02721
331111003944	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
331111003945	active site
331111003946	substrate binding site [chemical binding]; other site
331111003947	ATP binding site [chemical binding]; other site
331111003948	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
331111003949	beta-hexosaminidase; Provisional; Region: PRK05337
331111003950	hypothetical protein; Provisional; Region: PRK04940
331111003951	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
331111003952	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111003953	hypothetical protein; Provisional; Region: PRK11280
331111003954	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
331111003955	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
331111003956	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
331111003957	L,D-transpeptidase; Provisional; Region: PRK10260
331111003958	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
331111003959	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
331111003960	transcription-repair coupling factor; Provisional; Region: PRK10689
331111003961	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
331111003962	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
331111003963	ATP binding site [chemical binding]; other site
331111003964	putative Mg++ binding site [ion binding]; other site
331111003965	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111003966	nucleotide binding region [chemical binding]; other site
331111003967	ATP-binding site [chemical binding]; other site
331111003968	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
331111003969	Predicted membrane protein [Function unknown]; Region: COG4763
331111003970	Acyltransferase family; Region: Acyl_transf_3; pfam01757
331111003971	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
331111003972	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
331111003973	FtsX-like permease family; Region: FtsX; pfam02687
331111003974	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
331111003975	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
331111003976	Walker A/P-loop; other site
331111003977	ATP binding site [chemical binding]; other site
331111003978	Q-loop/lid; other site
331111003979	ABC transporter signature motif; other site
331111003980	Walker B; other site
331111003981	D-loop; other site
331111003982	H-loop/switch region; other site
331111003983	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
331111003984	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
331111003985	FtsX-like permease family; Region: FtsX; pfam02687
331111003986	fructokinase; Reviewed; Region: PRK09557
331111003987	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
331111003988	nucleotide binding site [chemical binding]; other site
331111003989	Repair protein; Region: Repair_PSII; cl01535
331111003990	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
331111003991	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
331111003992	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
331111003993	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
331111003994	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111003995	dimer interface [polypeptide binding]; other site
331111003996	conserved gate region; other site
331111003997	putative PBP binding loops; other site
331111003998	ABC-ATPase subunit interface; other site
331111003999	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
331111004000	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
331111004001	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
331111004002	dimer interface [polypeptide binding]; other site
331111004003	active site
331111004004	Int/Topo IB signature motif; other site
331111004005	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
331111004006	active site
331111004007	substrate binding site [chemical binding]; other site
331111004008	catalytic site [active]
331111004009	exonuclease VIII; Reviewed; Region: PRK09709
331111004010	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
331111004011	DicB protein; Region: DicB; pfam05358
331111004012	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
331111004013	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
331111004014	Helix-turn-helix domain; Region: HTH_36; pfam13730
331111004015	primosomal protein DnaI; Provisional; Region: PRK02854
331111004016	putative replication protein; Provisional; Region: PRK12377
331111004017	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111004018	Walker A motif; other site
331111004019	ATP binding site [chemical binding]; other site
331111004020	Walker B motif; other site
331111004021	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
331111004022	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
331111004023	Domain of unknown function (DUF4406); Region: DUF4406; pfam14359
331111004024	Protein of unknown function (DUF968); Region: DUF968; pfam06147
331111004025	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
331111004026	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
331111004027	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
331111004028	Catalytic domain of Protein Kinases; Region: PKc; cd00180
331111004029	active site
331111004030	ATP binding site [chemical binding]; other site
331111004031	substrate binding site [chemical binding]; other site
331111004032	activation loop (A-loop); other site
331111004033	Serine/threonine protein phosphatase [Signal transduction mechanisms]; Region: PTC1; COG0631
331111004034	active site
331111004035	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111004036	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
331111004037	DNA methylase; Region: N6_N4_Mtase; pfam01555
331111004038	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
331111004039	Protein of unknown function (DUF754); Region: DUF754; pfam05449
331111004040	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
331111004041	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
331111004042	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
331111004043	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
331111004044	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
331111004045	Phage Tail Collar Domain; Region: Collar; pfam07484
331111004046	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
331111004047	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
331111004048	Methyltransferase domain; Region: Methyltransf_31; pfam13847
331111004049	Methyltransferase domain; Region: Methyltransf_12; pfam08242
331111004050	S-adenosylmethionine binding site [chemical binding]; other site
331111004051	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
331111004052	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
331111004053	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111004054	dimer interface [polypeptide binding]; other site
331111004055	conserved gate region; other site
331111004056	putative PBP binding loops; other site
331111004057	ABC-ATPase subunit interface; other site
331111004058	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
331111004059	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111004060	Walker A/P-loop; other site
331111004061	ATP binding site [chemical binding]; other site
331111004062	Q-loop/lid; other site
331111004063	ABC transporter signature motif; other site
331111004064	Walker B; other site
331111004065	D-loop; other site
331111004066	H-loop/switch region; other site
331111004067	TOBE domain; Region: TOBE_2; pfam08402
331111004068	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
331111004069	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
331111004070	metal binding site [ion binding]; metal-binding site
331111004071	dimer interface [polypeptide binding]; other site
331111004072	Uncharacterized conserved protein [Function unknown]; Region: COG2850
331111004073	Cupin-like domain; Region: Cupin_8; pfam13621
331111004074	sensor protein PhoQ; Provisional; Region: PRK10815
331111004075	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
331111004076	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
331111004077	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
331111004078	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111004079	ATP binding site [chemical binding]; other site
331111004080	Mg2+ binding site [ion binding]; other site
331111004081	G-X-G motif; other site
331111004082	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
331111004083	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111004084	active site
331111004085	phosphorylation site [posttranslational modification]
331111004086	intermolecular recognition site; other site
331111004087	dimerization interface [polypeptide binding]; other site
331111004088	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
331111004089	DNA binding site [nucleotide binding]
331111004090	adenylosuccinate lyase; Provisional; Region: PRK09285
331111004091	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
331111004092	tetramer interface [polypeptide binding]; other site
331111004093	active site
331111004094	putative lysogenization regulator; Reviewed; Region: PRK00218
331111004095	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
331111004096	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
331111004097	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
331111004098	nudix motif; other site
331111004099	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
331111004100	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
331111004101	probable active site [active]
331111004102	isocitrate dehydrogenase; Validated; Region: PRK07362
331111004103	isocitrate dehydrogenase; Reviewed; Region: PRK07006
331111004104	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
331111004105	transcriptional regulator MirA; Provisional; Region: PRK15043
331111004106	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
331111004107	DNA binding residues [nucleotide binding]
331111004108	Sensors of blue-light using FAD; Region: BLUF; smart01034
331111004109	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
331111004110	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
331111004111	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
331111004112	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
331111004113	heme ABC transporter, heme-binding protein isdE; Region: IsdE; TIGR03659
331111004114	Autotransporter beta-domain; Region: Autotransporter; smart00869
331111004115	Autotransporter beta-domain; Region: Autotransporter; smart00869
331111004116	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
331111004117	cell division inhibitor MinD; Provisional; Region: PRK10818
331111004118	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
331111004119	Switch I; other site
331111004120	Switch II; other site
331111004121	septum formation inhibitor; Reviewed; Region: minC; PRK03511
331111004122	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
331111004123	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
331111004124	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
331111004125	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
331111004126	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
331111004127	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
331111004128	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
331111004129	hypothetical protein; Provisional; Region: PRK10691
331111004130	hypothetical protein; Provisional; Region: PRK05170
331111004131	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
331111004132	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
331111004133	Catalytic site [active]
331111004134	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
331111004135	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
331111004136	active site
331111004137	DNA binding site [nucleotide binding]
331111004138	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
331111004139	disulfide bond formation protein B; Provisional; Region: PRK01749
331111004140	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
331111004141	transmembrane helices; other site
331111004142	fatty acid metabolism regulator; Provisional; Region: PRK04984
331111004143	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111004144	DNA-binding site [nucleotide binding]; DNA binding site
331111004145	FadR C-terminal domain; Region: FadR_C; pfam07840
331111004146	SpoVR family protein; Provisional; Region: PRK11767
331111004147	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
331111004148	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
331111004149	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111004150	alanine racemase; Reviewed; Region: dadX; PRK03646
331111004151	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
331111004152	active site
331111004153	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
331111004154	substrate binding site [chemical binding]; other site
331111004155	catalytic residues [active]
331111004156	dimer interface [polypeptide binding]; other site
331111004157	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
331111004158	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
331111004159	TrkA-C domain; Region: TrkA_C; pfam02080
331111004160	Transporter associated domain; Region: CorC_HlyC; smart01091
331111004161	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
331111004162	dimer interface [polypeptide binding]; other site
331111004163	catalytic triad [active]
331111004164	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
331111004165	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
331111004166	N-acetyl-D-glucosamine binding site [chemical binding]; other site
331111004167	catalytic residue [active]
331111004168	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
331111004169	Flagellar regulator YcgR; Region: YcgR; pfam07317
331111004170	PilZ domain; Region: PilZ; pfam07238
331111004171	hypothetical protein; Provisional; Region: PRK10457
331111004172	trehalase; Provisional; Region: treA; PRK13271
331111004173	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
331111004174	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
331111004175	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3412
331111004176	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
331111004177	dimerization domain swap beta strand [polypeptide binding]; other site
331111004178	regulatory protein interface [polypeptide binding]; other site
331111004179	active site
331111004180	regulatory phosphorylation site [posttranslational modification]; other site
331111004181	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
331111004182	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
331111004183	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
331111004184	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
331111004185	Dak1 domain; Region: Dak1; pfam02733
331111004186	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
331111004187	PAS domain; Region: PAS; smart00091
331111004188	putative active site [active]
331111004189	heme pocket [chemical binding]; other site
331111004190	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111004191	Walker A motif; other site
331111004192	ATP binding site [chemical binding]; other site
331111004193	Walker B motif; other site
331111004194	arginine finger; other site
331111004195	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
331111004196	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
331111004197	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
331111004198	Autotransporter beta-domain; Region: Autotransporter; pfam03797
331111004199	GTP-binding protein YchF; Reviewed; Region: PRK09601
331111004200	YchF GTPase; Region: YchF; cd01900
331111004201	G1 box; other site
331111004202	GTP/Mg2+ binding site [chemical binding]; other site
331111004203	Switch I region; other site
331111004204	G2 box; other site
331111004205	Switch II region; other site
331111004206	G3 box; other site
331111004207	G4 box; other site
331111004208	G5 box; other site
331111004209	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
331111004210	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
331111004211	putative active site [active]
331111004212	catalytic residue [active]
331111004213	hypothetical protein; Provisional; Region: PRK10692
331111004214	putative transporter; Provisional; Region: PRK11660
331111004215	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
331111004216	Sulfate transporter family; Region: Sulfate_transp; pfam00916
331111004217	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
331111004218	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
331111004219	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
331111004220	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
331111004221	active site
331111004222	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
331111004223	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
331111004224	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
331111004225	outer membrane lipoprotein LolB; Region: lolB; TIGR00548
331111004226	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
331111004227	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
331111004228	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
331111004229	tRNA; other site
331111004230	putative tRNA binding site [nucleotide binding]; other site
331111004231	putative NADP binding site [chemical binding]; other site
331111004232	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
331111004233	peptide chain release factor 1; Validated; Region: prfA; PRK00591
331111004234	This domain is found in peptide chain release factors; Region: PCRF; smart00937
331111004235	RF-1 domain; Region: RF-1; pfam00472
331111004236	HemK family putative methylases; Region: hemK_fam; TIGR00536
331111004237	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111004238	hypothetical protein; Provisional; Region: PRK10278
331111004239	hypothetical protein; Provisional; Region: PRK10941
331111004240	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
331111004241	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
331111004242	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
331111004243	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
331111004244	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
331111004245	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
331111004246	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
331111004247	cation transport regulator; Reviewed; Region: chaB; PRK09582
331111004248	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
331111004249	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
331111004250	putative active site pocket [active]
331111004251	dimerization interface [polypeptide binding]; other site
331111004252	putative catalytic residue [active]
331111004253	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
331111004254	putative invasin; Provisional; Region: PRK10177
331111004255	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
331111004256	transcriptional regulator NarL; Provisional; Region: PRK10651
331111004257	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111004258	active site
331111004259	phosphorylation site [posttranslational modification]
331111004260	intermolecular recognition site; other site
331111004261	dimerization interface [polypeptide binding]; other site
331111004262	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111004263	DNA binding residues [nucleotide binding]
331111004264	dimerization interface [polypeptide binding]; other site
331111004265	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
331111004266	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
331111004267	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
331111004268	dimerization interface [polypeptide binding]; other site
331111004269	Histidine kinase; Region: HisKA_3; pfam07730
331111004270	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111004271	ATP binding site [chemical binding]; other site
331111004272	Mg2+ binding site [ion binding]; other site
331111004273	G-X-G motif; other site
331111004274	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
331111004275	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
331111004276	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
331111004277	[4Fe-4S] binding site [ion binding]; other site
331111004278	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
331111004279	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
331111004280	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
331111004281	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
331111004282	molybdopterin cofactor binding site; other site
331111004283	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
331111004284	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
331111004285	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
331111004286	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
331111004287	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
331111004288	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
331111004289	putative active site [active]
331111004290	putative substrate binding site [chemical binding]; other site
331111004291	putative cosubstrate binding site; other site
331111004292	catalytic site [active]
331111004293	SEC-C motif; Region: SEC-C; pfam02810
331111004294	hypothetical protein; Provisional; Region: PRK04233
331111004295	hypothetical protein; Provisional; Region: PRK10279
331111004296	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
331111004297	active site
331111004298	nucleophile elbow; other site
331111004299	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111004300	active site
331111004301	response regulator of RpoS; Provisional; Region: PRK10693
331111004302	phosphorylation site [posttranslational modification]
331111004303	intermolecular recognition site; other site
331111004304	dimerization interface [polypeptide binding]; other site
331111004305	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
331111004306	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
331111004307	active site
331111004308	tetramer interface; other site
331111004309	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
331111004310	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
331111004311	thymidine kinase; Provisional; Region: PRK04296
331111004312	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
331111004313	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
331111004314	putative catalytic cysteine [active]
331111004315	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
331111004316	putative active site [active]
331111004317	metal binding site [ion binding]; metal-binding site
331111004318	hypothetical protein; Provisional; Region: PRK11111
331111004319	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
331111004320	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
331111004321	peptide binding site [polypeptide binding]; other site
331111004322	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
331111004323	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111004324	dimer interface [polypeptide binding]; other site
331111004325	conserved gate region; other site
331111004326	putative PBP binding loops; other site
331111004327	ABC-ATPase subunit interface; other site
331111004328	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
331111004329	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
331111004330	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111004331	dimer interface [polypeptide binding]; other site
331111004332	conserved gate region; other site
331111004333	putative PBP binding loops; other site
331111004334	ABC-ATPase subunit interface; other site
331111004335	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
331111004336	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
331111004337	Walker A/P-loop; other site
331111004338	ATP binding site [chemical binding]; other site
331111004339	Q-loop/lid; other site
331111004340	ABC transporter signature motif; other site
331111004341	Walker B; other site
331111004342	D-loop; other site
331111004343	H-loop/switch region; other site
331111004344	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
331111004345	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
331111004346	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
331111004347	Walker A/P-loop; other site
331111004348	ATP binding site [chemical binding]; other site
331111004349	Q-loop/lid; other site
331111004350	ABC transporter signature motif; other site
331111004351	Walker B; other site
331111004352	D-loop; other site
331111004353	H-loop/switch region; other site
331111004354	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
331111004355	dsDNA-mimic protein; Reviewed; Region: PRK05094
331111004356	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
331111004357	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
331111004358	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
331111004359	putative active site [active]
331111004360	catalytic site [active]
331111004361	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
331111004362	putative active site [active]
331111004363	catalytic site [active]
331111004364	voltage-gated potassium channel; Provisional; Region: PRK10537
331111004365	Ion channel; Region: Ion_trans_2; pfam07885
331111004366	TrkA-N domain; Region: TrkA_N; pfam02254
331111004367	YciI-like protein; Reviewed; Region: PRK11370
331111004368	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; cl05442
331111004369	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
331111004370	Helix-turn-helix domain; Region: HTH_36; pfam13730
331111004371	tape measure domain; Region: tape_meas_nterm; TIGR02675
331111004372	Transposase; Region: HTH_Tnp_1; pfam01527
331111004373	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111004374	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111004375	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111004376	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
331111004377	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111004378	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
331111004379	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
331111004380	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111004381	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
331111004382	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
331111004383	catalytic residues [active]
331111004384	catalytic nucleophile [active]
331111004385	Recombinase; Region: Recombinase; pfam07508
331111004386	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
331111004387	transport protein TonB; Provisional; Region: PRK10819
331111004388	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
331111004389	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
331111004390	intracellular septation protein A; Reviewed; Region: PRK00259
331111004391	hypothetical protein; Provisional; Region: PRK02868
331111004392	outer membrane protein W; Provisional; Region: PRK10959
331111004393	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
331111004394	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
331111004395	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
331111004396	dimer interface [polypeptide binding]; other site
331111004397	active site
331111004398	Int/Topo IB signature motif; other site
331111004399	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
331111004400	active site
331111004401	catalytic site [active]
331111004402	substrate binding site [chemical binding]; other site
331111004403	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
331111004404	Ash protein family; Region: Phage_ASH; pfam10554
331111004405	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
331111004406	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
331111004407	DNA-binding transcriptional regulator DicC; Provisional; Region: PRK09744
331111004408	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
331111004409	Pyocin large subunit [General function prediction only]; Region: COG5529
331111004410	Helix-turn-helix domain; Region: HTH_36; pfam13730
331111004411	primosomal protein DnaI; Provisional; Region: PRK02854
331111004412	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
331111004413	Domain of unknown function (DUF4406); Region: DUF4406; pfam14359
331111004414	Protein of unknown function (DUF968); Region: DUF968; pfam06147
331111004415	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
331111004416	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
331111004417	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
331111004418	Catalytic domain of Protein Kinases; Region: PKc; cd00180
331111004419	active site
331111004420	ATP binding site [chemical binding]; other site
331111004421	substrate binding site [chemical binding]; other site
331111004422	activation loop (A-loop); other site
331111004423	Serine/threonine protein phosphatase [Signal transduction mechanisms]; Region: PTC1; COG0631
331111004424	active site
331111004425	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111004426	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
331111004427	DNA methylase; Region: N6_N4_Mtase; pfam01555
331111004428	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
331111004429	gpW; Region: gpW; pfam02831
331111004430	Phage portal protein, lambda family; Region: Phage_portal_2; pfam05136
331111004431	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
331111004432	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
331111004433	Baseplate J-like protein; Region: Baseplate_J; cl01294
331111004434	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; pfam10076
331111004435	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
331111004436	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
331111004437	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
331111004438	Leucine rich repeats (6 copies); Region: LRR_5; pfam13306
331111004439	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
331111004440	ORF6N domain; Region: ORF6N; pfam10543
331111004441	OmpW family; Region: OmpW; cl17427
331111004442	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3685
331111004443	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
331111004444	dimerization interface [polypeptide binding]; other site
331111004445	metal binding site [ion binding]; metal-binding site
331111004446	General stress protein [General function prediction only]; Region: GsiB; COG3729
331111004447	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
331111004448	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
331111004449	substrate binding site [chemical binding]; other site
331111004450	active site
331111004451	catalytic residues [active]
331111004452	heterodimer interface [polypeptide binding]; other site
331111004453	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
331111004454	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
331111004455	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111004456	catalytic residue [active]
331111004457	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
331111004458	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
331111004459	active site
331111004460	ribulose/triose binding site [chemical binding]; other site
331111004461	phosphate binding site [ion binding]; other site
331111004462	substrate (anthranilate) binding pocket [chemical binding]; other site
331111004463	product (indole) binding pocket [chemical binding]; other site
331111004464	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
331111004465	active site
331111004466	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
331111004467	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
331111004468	glutamine binding [chemical binding]; other site
331111004469	catalytic triad [active]
331111004470	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
331111004471	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
331111004472	anthranilate synthase component I; Provisional; Region: PRK13564
331111004473	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
331111004474	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
331111004475	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
331111004476	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
331111004477	active site
331111004478	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
331111004479	hypothetical protein; Provisional; Region: PRK11630
331111004480	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
331111004481	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
331111004482	RNA binding surface [nucleotide binding]; other site
331111004483	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
331111004484	probable active site [active]
331111004485	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
331111004486	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
331111004487	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
331111004488	homodimer interface [polypeptide binding]; other site
331111004489	Walker A motif; other site
331111004490	ATP binding site [chemical binding]; other site
331111004491	hydroxycobalamin binding site [chemical binding]; other site
331111004492	Walker B motif; other site
331111004493	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
331111004494	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
331111004495	NADP binding site [chemical binding]; other site
331111004496	homodimer interface [polypeptide binding]; other site
331111004497	active site
331111004498	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
331111004499	putative inner membrane peptidase; Provisional; Region: PRK11778
331111004500	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
331111004501	tandem repeat interface [polypeptide binding]; other site
331111004502	oligomer interface [polypeptide binding]; other site
331111004503	active site residues [active]
331111004504	hypothetical protein; Provisional; Region: PRK11037
331111004505	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
331111004506	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
331111004507	active site
331111004508	interdomain interaction site; other site
331111004509	putative metal-binding site [ion binding]; other site
331111004510	nucleotide binding site [chemical binding]; other site
331111004511	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
331111004512	domain I; other site
331111004513	DNA binding groove [nucleotide binding]
331111004514	phosphate binding site [ion binding]; other site
331111004515	domain II; other site
331111004516	domain III; other site
331111004517	nucleotide binding site [chemical binding]; other site
331111004518	catalytic site [active]
331111004519	domain IV; other site
331111004520	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
331111004521	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
331111004522	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
331111004523	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
331111004524	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
331111004525	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111004526	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
331111004527	substrate binding site [chemical binding]; other site
331111004528	putative dimerization interface [polypeptide binding]; other site
331111004529	aconitate hydratase; Validated; Region: PRK09277
331111004530	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
331111004531	substrate binding site [chemical binding]; other site
331111004532	ligand binding site [chemical binding]; other site
331111004533	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
331111004534	substrate binding site [chemical binding]; other site
331111004535	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
331111004536	dimerization interface [polypeptide binding]; other site
331111004537	active site
331111004538	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
331111004539	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
331111004540	active site
331111004541	Predicted membrane protein [Function unknown]; Region: COG3771
331111004542	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
331111004543	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
331111004544	TPR motif; other site
331111004545	binding surface
331111004546	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
331111004547	binding surface
331111004548	TPR motif; other site
331111004549	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
331111004550	active site
331111004551	dimer interface [polypeptide binding]; other site
331111004552	translation initiation factor Sui1; Validated; Region: PRK06824
331111004553	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
331111004554	putative rRNA binding site [nucleotide binding]; other site
331111004555	lipoprotein; Provisional; Region: PRK10540
331111004556	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
331111004557	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
331111004558	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
331111004559	hypothetical protein; Provisional; Region: PRK13658
331111004560	RNase II stability modulator; Provisional; Region: PRK10060
331111004561	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
331111004562	putative active site [active]
331111004563	heme pocket [chemical binding]; other site
331111004564	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111004565	metal binding site [ion binding]; metal-binding site
331111004566	active site
331111004567	I-site; other site
331111004568	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
331111004569	exoribonuclease II; Provisional; Region: PRK05054
331111004570	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
331111004571	RNB domain; Region: RNB; pfam00773
331111004572	S1 RNA binding domain; Region: S1; pfam00575
331111004573	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
331111004574	Uncharacterized conserved protein [Function unknown]; Region: COG2128
331111004575	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
331111004576	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
331111004577	NAD binding site [chemical binding]; other site
331111004578	homotetramer interface [polypeptide binding]; other site
331111004579	homodimer interface [polypeptide binding]; other site
331111004580	substrate binding site [chemical binding]; other site
331111004581	active site
331111004582	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
331111004583	putative active site [active]
331111004584	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
331111004585	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
331111004586	Walker A/P-loop; other site
331111004587	ATP binding site [chemical binding]; other site
331111004588	Q-loop/lid; other site
331111004589	ABC transporter signature motif; other site
331111004590	Walker B; other site
331111004591	D-loop; other site
331111004592	H-loop/switch region; other site
331111004593	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
331111004594	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
331111004595	Walker A/P-loop; other site
331111004596	ATP binding site [chemical binding]; other site
331111004597	Q-loop/lid; other site
331111004598	ABC transporter signature motif; other site
331111004599	Walker B; other site
331111004600	D-loop; other site
331111004601	H-loop/switch region; other site
331111004602	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
331111004603	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
331111004604	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
331111004605	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111004606	dimer interface [polypeptide binding]; other site
331111004607	conserved gate region; other site
331111004608	putative PBP binding loops; other site
331111004609	ABC-ATPase subunit interface; other site
331111004610	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
331111004611	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111004612	dimer interface [polypeptide binding]; other site
331111004613	conserved gate region; other site
331111004614	putative PBP binding loops; other site
331111004615	ABC-ATPase subunit interface; other site
331111004616	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
331111004617	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
331111004618	peptide binding site [polypeptide binding]; other site
331111004619	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
331111004620	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
331111004621	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
331111004622	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
331111004623	gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional; Region: puuD; PRK11366
331111004624	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
331111004625	catalytic triad [active]
331111004626	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
331111004627	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111004628	non-specific DNA binding site [nucleotide binding]; other site
331111004629	salt bridge; other site
331111004630	sequence-specific DNA binding site [nucleotide binding]; other site
331111004631	Cupin domain; Region: Cupin_2; pfam07883
331111004632	gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK09847
331111004633	Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112
331111004634	NAD(P) binding site [chemical binding]; other site
331111004635	catalytic residues [active]
331111004636	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
331111004637	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
331111004638	4-aminobutyrate transaminase; Provisional; Region: PRK09792
331111004639	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
331111004640	inhibitor-cofactor binding pocket; inhibition site
331111004641	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111004642	catalytic residue [active]
331111004643	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
331111004644	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111004645	Walker A motif; other site
331111004646	ATP binding site [chemical binding]; other site
331111004647	Walker B motif; other site
331111004648	arginine finger; other site
331111004649	phage shock protein PspA; Provisional; Region: PRK10698
331111004650	phage shock protein B; Provisional; Region: pspB; PRK09458
331111004651	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
331111004652	phage shock protein C; Region: phageshock_pspC; TIGR02978
331111004653	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
331111004654	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
331111004655	active site residue [active]
331111004656	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
331111004657	sucrose phosphorylase; Provisional; Region: PRK13840
331111004658	active site
331111004659	homodimer interface [polypeptide binding]; other site
331111004660	catalytic site [active]
331111004661	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
331111004662	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
331111004663	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
331111004664	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111004665	dimer interface [polypeptide binding]; other site
331111004666	conserved gate region; other site
331111004667	putative PBP binding loops; other site
331111004668	ABC-ATPase subunit interface; other site
331111004669	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
331111004670	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111004671	dimer interface [polypeptide binding]; other site
331111004672	conserved gate region; other site
331111004673	putative PBP binding loops; other site
331111004674	ABC-ATPase subunit interface; other site
331111004675	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
331111004676	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
331111004677	putative NAD(P) binding site [chemical binding]; other site
331111004678	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
331111004679	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
331111004680	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
331111004681	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
331111004682	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
331111004683	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
331111004684	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
331111004685	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
331111004686	beta-phosphoglucomutase; Region: bPGM; TIGR01990
331111004687	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111004688	motif II; other site
331111004689	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
331111004690	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
331111004691	Walker A/P-loop; other site
331111004692	ATP binding site [chemical binding]; other site
331111004693	Q-loop/lid; other site
331111004694	ABC transporter signature motif; other site
331111004695	Walker B; other site
331111004696	D-loop; other site
331111004697	H-loop/switch region; other site
331111004698	TOBE domain; Region: TOBE_2; pfam08402
331111004699	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
331111004700	Transcriptional regulators [Transcription]; Region: PurR; COG1609
331111004701	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
331111004702	DNA binding site [nucleotide binding]
331111004703	domain linker motif; other site
331111004704	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
331111004705	putative dimerization interface [polypeptide binding]; other site
331111004706	putative ligand binding site [chemical binding]; other site
331111004707	Predicted ATPase [General function prediction only]; Region: COG3106
331111004708	Predicted membrane protein [Function unknown]; Region: COG3768
331111004709	TIGR01620 family protein; Region: hyp_HI0043
331111004710	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
331111004711	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
331111004712	putative aromatic amino acid binding site; other site
331111004713	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111004714	Walker A motif; other site
331111004715	ATP binding site [chemical binding]; other site
331111004716	Walker B motif; other site
331111004717	arginine finger; other site
331111004718	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
331111004719	dimer interface [polypeptide binding]; other site
331111004720	catalytic triad [active]
331111004721	peroxidatic and resolving cysteines [active]
331111004722	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
331111004723	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
331111004724	active site
331111004725	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
331111004726	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
331111004727	putative active site [active]
331111004728	Zn binding site [ion binding]; other site
331111004729	atypical (a) SDRs, subgroup 6; Region: SDR_a6; cd05267
331111004730	NADH(P)-binding; Region: NAD_binding_10; pfam13460
331111004731	putative NAD(P) binding site [chemical binding]; other site
331111004732	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
331111004733	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
331111004734	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
331111004735	Transcriptional regulator [Transcription]; Region: LysR; COG0583
331111004736	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111004737	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
331111004738	putative effector binding pocket; other site
331111004739	putative dimerization interface [polypeptide binding]; other site
331111004740	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
331111004741	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
331111004742	peptide binding site [polypeptide binding]; other site
331111004743	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
331111004744	Mechanosensitive ion channel; Region: MS_channel; pfam00924
331111004745	universal stress protein UspE; Provisional; Region: PRK11175
331111004746	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
331111004747	Ligand Binding Site [chemical binding]; other site
331111004748	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
331111004749	Ligand Binding Site [chemical binding]; other site
331111004750	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
331111004751	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
331111004752	ligand binding site [chemical binding]; other site
331111004753	flexible hinge region; other site
331111004754	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
331111004755	putative switch regulator; other site
331111004756	non-specific DNA interactions [nucleotide binding]; other site
331111004757	DNA binding site [nucleotide binding]
331111004758	sequence specific DNA binding site [nucleotide binding]; other site
331111004759	putative cAMP binding site [chemical binding]; other site
331111004760	putative aminobenzoyl-glutamate transporter; Provisional; Region: abgT; PRK11339
331111004761	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
331111004762	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
331111004763	amidohydrolase; Region: amidohydrolases; TIGR01891
331111004764	putative metal binding site [ion binding]; other site
331111004765	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
331111004766	amidohydrolase; Region: amidohydrolases; TIGR01891
331111004767	putative metal binding site [ion binding]; other site
331111004768	dimer interface [polypeptide binding]; other site
331111004769	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
331111004770	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111004771	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
331111004772	putative substrate binding pocket [chemical binding]; other site
331111004773	putative dimerization interface [polypeptide binding]; other site
331111004774	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
331111004775	Smr domain; Region: Smr; pfam01713
331111004776	PAS domain S-box; Region: sensory_box; TIGR00229
331111004777	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
331111004778	putative active site [active]
331111004779	heme pocket [chemical binding]; other site
331111004780	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
331111004781	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111004782	metal binding site [ion binding]; metal-binding site
331111004783	active site
331111004784	I-site; other site
331111004785	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
331111004786	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
331111004787	Cl binding site [ion binding]; other site
331111004788	oligomer interface [polypeptide binding]; other site
331111004789	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
331111004790	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
331111004791	ATP binding site [chemical binding]; other site
331111004792	Mg++ binding site [ion binding]; other site
331111004793	motif III; other site
331111004794	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111004795	nucleotide binding region [chemical binding]; other site
331111004796	ATP-binding site [chemical binding]; other site
331111004797	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
331111004798	putative RNA binding site [nucleotide binding]; other site
331111004799	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
331111004800	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
331111004801	Ligand Binding Site [chemical binding]; other site
331111004802	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
331111004803	Ligand Binding Site [chemical binding]; other site
331111004804	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
331111004805	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
331111004806	trimer interface [polypeptide binding]; other site
331111004807	eyelet of channel; other site
331111004808	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
331111004809	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
331111004810	dimer interface [polypeptide binding]; other site
331111004811	PYR/PP interface [polypeptide binding]; other site
331111004812	TPP binding site [chemical binding]; other site
331111004813	substrate binding site [chemical binding]; other site
331111004814	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
331111004815	Domain of unknown function; Region: EKR; smart00890
331111004816	4Fe-4S binding domain; Region: Fer4_6; pfam12837
331111004817	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
331111004818	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
331111004819	TPP-binding site [chemical binding]; other site
331111004820	dimer interface [polypeptide binding]; other site
331111004821	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
331111004822	Domain of unknown function (DUF333); Region: DUF333; pfam03891
331111004823	heat-inducible protein; Provisional; Region: PRK10449
331111004824	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
331111004825	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
331111004826	putative ligand binding site [chemical binding]; other site
331111004827	putative NAD binding site [chemical binding]; other site
331111004828	catalytic site [active]
331111004829	hypothetical protein; Provisional; Region: PRK10695
331111004830	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
331111004831	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
331111004832	DNA-binding transcriptional activator FeaR; Provisional; Region: PRK09685
331111004833	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111004834	Escherichia coli NAD+-dependent phenylacetaldehyde dehydrogenase PadA-like; Region: ALDH_PADH_NahF; cd07113
331111004835	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
331111004836	NAD(P) binding site [chemical binding]; other site
331111004837	catalytic residues [active]
331111004838	tyramine oxidase; Provisional; Region: tynA; PRK14696
331111004839	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
331111004840	Copper amine oxidase, N2 domain; Region: Cu_amine_oxidN2; pfam02727
331111004841	Copper amine oxidase, N3 domain; Region: Cu_amine_oxidN3; pfam02728
331111004842	Copper amine oxidase, enzyme domain; Region: Cu_amine_oxid; pfam01179
331111004843	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Provisional; Region: PRK11563
331111004844	N-terminal domain of the monoamine oxidase C dehydratase; Region: ALDH_MaoC-N; cd07128
331111004845	substrate binding site [chemical binding]; other site
331111004846	dimer interface [polypeptide binding]; other site
331111004847	NADP binding site [chemical binding]; other site
331111004848	catalytic residues [active]
331111004849	MaoC_C  The C-terminal hot dog fold of the MaoC (monoamine oxidase C) dehydratase regulatory protein. Orthologs of MaoC include PaaZ [Escherichia coli] and PaaN [Pseudomonas putida], which are putative ring-opening enzymes involved in phenylacetic acid...; Region: MaoC_C; cd03452
331111004850	substrate binding site [chemical binding]; other site
331111004851	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
331111004852	phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156
331111004853	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
331111004854	phenylacetate-CoA oxygenase, PaaI subunit; Region: PA_CoA_Oxy3; TIGR02158
331111004855	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
331111004856	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
331111004857	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
331111004858	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
331111004859	FAD binding pocket [chemical binding]; other site
331111004860	FAD binding motif [chemical binding]; other site
331111004861	phosphate binding motif [ion binding]; other site
331111004862	beta-alpha-beta structure motif; other site
331111004863	NAD(p) ribose binding residues [chemical binding]; other site
331111004864	NAD binding pocket [chemical binding]; other site
331111004865	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
331111004866	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
331111004867	catalytic loop [active]
331111004868	iron binding site [ion binding]; other site
331111004869	enoyl-CoA hydratase-isomerase; Provisional; Region: PRK09674
331111004870	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
331111004871	substrate binding site [chemical binding]; other site
331111004872	oxyanion hole (OAH) forming residues; other site
331111004873	trimer interface [polypeptide binding]; other site
331111004874	enoyl-CoA hydratase; Provisional; Region: PRK08140
331111004875	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
331111004876	substrate binding site [chemical binding]; other site
331111004877	oxyanion hole (OAH) forming residues; other site
331111004878	trimer interface [polypeptide binding]; other site
331111004879	3-hydroxyacyl-CoA dehydrogenase PaaC; Region: PaaC-3OHAcCoADH; TIGR02279
331111004880	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
331111004881	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
331111004882	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
331111004883	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
331111004884	CoenzymeA binding site [chemical binding]; other site
331111004885	subunit interaction site [polypeptide binding]; other site
331111004886	PHB binding site; other site
331111004887	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
331111004888	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
331111004889	dimer interface [polypeptide binding]; other site
331111004890	active site
331111004891	Phenylacetate-CoA ligase (also known as PaaK); Region: PaaK; cd05913
331111004892	phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155
331111004893	active site
331111004894	AMP binding site [chemical binding]; other site
331111004895	homodimer interface [polypeptide binding]; other site
331111004896	acyl-activating enzyme (AAE) consensus motif; other site
331111004897	CoA binding site [chemical binding]; other site
331111004898	PaaX-like protein; Region: PaaX; pfam07848
331111004899	phenylacetic acid degradation operon negative regulatory protein PaaX; Region: PaaX_trns_reg; TIGR02277
331111004900	PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223
331111004901	phenylacetic acid degradation protein PaaY; Region: PaaY; TIGR02287
331111004902	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
331111004903	putative trimer interface [polypeptide binding]; other site
331111004904	putative metal binding site [ion binding]; other site
331111004905	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
331111004906	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
331111004907	active site
331111004908	catalytic tetrad [active]
331111004909	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
331111004910	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
331111004911	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
331111004912	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
331111004913	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
331111004914	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111004915	S-adenosylmethionine binding site [chemical binding]; other site
331111004916	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
331111004917	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
331111004918	active site
331111004919	Dual specificity phosphatase, catalytic domain; Region: DSPc; pfam00782
331111004920	active site
331111004921	catalytic residues [active]
331111004922	azoreductase; Reviewed; Region: PRK00170
331111004923	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
331111004924	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
331111004925	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
331111004926	ATP binding site [chemical binding]; other site
331111004927	putative Mg++ binding site [ion binding]; other site
331111004928	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111004929	nucleotide binding region [chemical binding]; other site
331111004930	ATP-binding site [chemical binding]; other site
331111004931	Helicase associated domain (HA2); Region: HA2; pfam04408
331111004932	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
331111004933	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
331111004934	Uncharacterized conserved protein [Function unknown]; Region: COG1434
331111004935	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
331111004936	putative active site [active]
331111004937	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
331111004938	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
331111004939	NAD binding site [chemical binding]; other site
331111004940	catalytic residues [active]
331111004941	substrate binding site [chemical binding]; other site
331111004942	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
331111004943	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
331111004944	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
331111004945	cytochrome b561; Provisional; Region: PRK11513
331111004946	hypothetical protein; Provisional; Region: PRK10040
331111004947	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
331111004948	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
331111004949	dimer interface [polypeptide binding]; other site
331111004950	ligand binding site [chemical binding]; other site
331111004951	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
331111004952	dimerization interface [polypeptide binding]; other site
331111004953	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
331111004954	dimer interface [polypeptide binding]; other site
331111004955	putative CheW interface [polypeptide binding]; other site
331111004956	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
331111004957	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111004958	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
331111004959	dimerization interface [polypeptide binding]; other site
331111004960	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
331111004961	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
331111004962	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
331111004963	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
331111004964	hypothetical protein; Provisional; Region: PRK11415
331111004965	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
331111004966	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
331111004967	Coenzyme A binding pocket [chemical binding]; other site
331111004968	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
331111004969	putative trimer interface [polypeptide binding]; other site
331111004970	putative CoA binding site [chemical binding]; other site
331111004971	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
331111004972	putative trimer interface [polypeptide binding]; other site
331111004973	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
331111004974	putative CoA binding site [chemical binding]; other site
331111004975	putative trimer interface [polypeptide binding]; other site
331111004976	putative CoA binding site [chemical binding]; other site
331111004977	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
331111004978	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
331111004979	gating phenylalanine in ion channel; other site
331111004980	tellurite resistance protein TehB; Provisional; Region: PRK11207
331111004981	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111004982	S-adenosylmethionine binding site [chemical binding]; other site
331111004983	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
331111004984	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
331111004985	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
331111004986	Probable transposase; Region: OrfB_IS605; pfam01385
331111004987	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
331111004988	benzoate transporter; Region: benE; TIGR00843
331111004989	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
331111004990	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
331111004991	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111004992	non-specific DNA binding site [nucleotide binding]; other site
331111004993	salt bridge; other site
331111004994	sequence-specific DNA binding site [nucleotide binding]; other site
331111004995	Cupin domain; Region: Cupin_2; pfam07883
331111004996	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
331111004997	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
331111004998	Peptidase family U32; Region: Peptidase_U32; pfam01136
331111004999	Collagenase; Region: DUF3656; pfam12392
331111005000	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
331111005001	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
331111005002	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111005003	sequence-specific DNA binding site [nucleotide binding]; other site
331111005004	salt bridge; other site
331111005005	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
331111005006	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111005007	DNA-binding site [nucleotide binding]; DNA binding site
331111005008	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
331111005009	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111005010	homodimer interface [polypeptide binding]; other site
331111005011	catalytic residue [active]
331111005012	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
331111005013	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
331111005014	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
331111005015	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111005016	Walker A/P-loop; other site
331111005017	ATP binding site [chemical binding]; other site
331111005018	Q-loop/lid; other site
331111005019	ABC transporter signature motif; other site
331111005020	Walker B; other site
331111005021	D-loop; other site
331111005022	H-loop/switch region; other site
331111005023	TOBE domain; Region: TOBE_2; pfam08402
331111005024	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111005025	dimer interface [polypeptide binding]; other site
331111005026	conserved gate region; other site
331111005027	putative PBP binding loops; other site
331111005028	ABC-ATPase subunit interface; other site
331111005029	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
331111005030	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111005031	ABC-ATPase subunit interface; other site
331111005032	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
331111005033	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
331111005034	tetrameric interface [polypeptide binding]; other site
331111005035	NAD binding site [chemical binding]; other site
331111005036	catalytic residues [active]
331111005037	substrate binding site [chemical binding]; other site
331111005038	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
331111005039	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
331111005040	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
331111005041	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
331111005042	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
331111005043	Coenzyme A binding pocket [chemical binding]; other site
331111005044	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
331111005045	Prostaglandin dehydrogenases; Region: PGDH; cd05288
331111005046	NAD(P) binding site [chemical binding]; other site
331111005047	substrate binding site [chemical binding]; other site
331111005048	dimer interface [polypeptide binding]; other site
331111005049	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
331111005050	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111005051	DNA-binding site [nucleotide binding]; DNA binding site
331111005052	FCD domain; Region: FCD; pfam07729
331111005053	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
331111005054	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
331111005055	N-terminal plug; other site
331111005056	ligand-binding site [chemical binding]; other site
331111005057	PQQ-like domain; Region: PQQ_2; pfam13360
331111005058	L-asparagine permease; Provisional; Region: PRK15049
331111005059	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
331111005060	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
331111005061	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
331111005062	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
331111005063	PAAR motif; Region: PAAR_motif; cl15808
331111005064	RHS Repeat; Region: RHS_repeat; pfam05593
331111005065	RHS Repeat; Region: RHS_repeat; pfam05593
331111005066	RHS Repeat; Region: RHS_repeat; pfam05593
331111005067	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
331111005068	RHS Repeat; Region: RHS_repeat; pfam05593
331111005069	RHS Repeat; Region: RHS_repeat; pfam05593
331111005070	RHS protein; Region: RHS; pfam03527
331111005071	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
331111005072	4-oxalocrotonate tautomerase; Provisional; Region: PRK01271
331111005073	active site 1 [active]
331111005074	dimer interface [polypeptide binding]; other site
331111005075	hexamer interface [polypeptide binding]; other site
331111005076	active site 2 [active]
331111005077	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
331111005078	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
331111005079	hypothetical protein; Provisional; Region: PRK10281
331111005080	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
331111005081	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
331111005082	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
331111005083	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
331111005084	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
331111005085	[4Fe-4S] binding site [ion binding]; other site
331111005086	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
331111005087	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
331111005088	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
331111005089	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
331111005090	molybdopterin cofactor binding site; other site
331111005091	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
331111005092	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
331111005093	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
331111005094	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
331111005095	aromatic amino acid exporter; Provisional; Region: PRK11689
331111005096	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
331111005097	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
331111005098	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
331111005099	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
331111005100	molybdopterin cofactor binding site; other site
331111005101	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
331111005102	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
331111005103	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
331111005104	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
331111005105	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
331111005106	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111005107	non-specific DNA binding site [nucleotide binding]; other site
331111005108	salt bridge; other site
331111005109	sequence-specific DNA binding site [nucleotide binding]; other site
331111005110	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
331111005111	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
331111005112	NAD binding site [chemical binding]; other site
331111005113	substrate binding site [chemical binding]; other site
331111005114	catalytic Zn binding site [ion binding]; other site
331111005115	tetramer interface [polypeptide binding]; other site
331111005116	structural Zn binding site [ion binding]; other site
331111005117	malate dehydrogenase; Provisional; Region: PRK13529
331111005118	Malic enzyme, N-terminal domain; Region: malic; pfam00390
331111005119	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
331111005120	NAD(P) binding site [chemical binding]; other site
331111005121	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
331111005122	Putative biofilm-dependent modulation protein; Region: BDM; cl11581
331111005123	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
331111005124	3-hydroxybutyrate dehydrogenase; Provisional; Region: PRK12429
331111005125	d-3-hydroxybutyrate dehydrogenase (HBDH), classical (c) SDRs; Region: HBDH_SDR_c; cd08940
331111005126	NAD binding site [chemical binding]; other site
331111005127	homotetramer interface [polypeptide binding]; other site
331111005128	homodimer interface [polypeptide binding]; other site
331111005129	substrate binding site [chemical binding]; other site
331111005130	active site
331111005131	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
331111005132	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
331111005133	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
331111005134	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
331111005135	putative acyltransferase; Provisional; Region: PRK05790
331111005136	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
331111005137	dimer interface [polypeptide binding]; other site
331111005138	active site
331111005139	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
331111005140	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
331111005141	Transcriptional regulator [Transcription]; Region: LysR; COG0583
331111005142	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111005143	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
331111005144	putative dimerization interface [polypeptide binding]; other site
331111005145	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
331111005146	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
331111005147	Walker A/P-loop; other site
331111005148	ATP binding site [chemical binding]; other site
331111005149	Q-loop/lid; other site
331111005150	ABC transporter signature motif; other site
331111005151	Walker B; other site
331111005152	D-loop; other site
331111005153	H-loop/switch region; other site
331111005154	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
331111005155	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
331111005156	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
331111005157	Walker A/P-loop; other site
331111005158	ATP binding site [chemical binding]; other site
331111005159	Q-loop/lid; other site
331111005160	ABC transporter signature motif; other site
331111005161	Walker B; other site
331111005162	D-loop; other site
331111005163	H-loop/switch region; other site
331111005164	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
331111005165	D-ala-D-ala transporter subunit; Provisional; Region: PRK09881
331111005166	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
331111005167	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111005168	dimer interface [polypeptide binding]; other site
331111005169	conserved gate region; other site
331111005170	putative PBP binding loops; other site
331111005171	ABC-ATPase subunit interface; other site
331111005172	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
331111005173	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111005174	dimer interface [polypeptide binding]; other site
331111005175	conserved gate region; other site
331111005176	putative PBP binding loops; other site
331111005177	ABC-ATPase subunit interface; other site
331111005178	D-alanyl-D-alanine dipeptidase; Provisional; Region: PRK10178
331111005179	cyclic-di-GMP phosphodiesterase; Provisional; Region: PRK11359
331111005180	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
331111005181	putative active site [active]
331111005182	heme pocket [chemical binding]; other site
331111005183	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
331111005184	putative active site [active]
331111005185	heme pocket [chemical binding]; other site
331111005186	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111005187	metal binding site [ion binding]; metal-binding site
331111005188	active site
331111005189	I-site; other site
331111005190	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
331111005191	Globin domain present in Globin-Coupled-Sensors (GCS). These domains detect changes in intracellular concentrations of oxygen, carbon monoxyde, or nitrous oxide,  which result in aerotaxis and/or gene regulation. One subgroup, the HemATs, are aerotactic...; Region: sensor_globin; cd01068
331111005192	heme-binding site [chemical binding]; other site
331111005193	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
331111005194	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111005195	metal binding site [ion binding]; metal-binding site
331111005196	active site
331111005197	I-site; other site
331111005198	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
331111005199	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
331111005200	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
331111005201	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
331111005202	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111005203	catalytic residue [active]
331111005204	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
331111005205	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
331111005206	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
331111005207	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
331111005208	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
331111005209	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
331111005210	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
331111005211	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
331111005212	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
331111005213	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
331111005214	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
331111005215	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111005216	FeS/SAM binding site; other site
331111005217	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
331111005218	transcriptional regulator YdeO; Provisional; Region: PRK09940
331111005219	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111005220	putative oxidoreductase; Provisional; Region: PRK09939
331111005221	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
331111005222	putative molybdopterin cofactor binding site [chemical binding]; other site
331111005223	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
331111005224	putative molybdopterin cofactor binding site; other site
331111005225	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
331111005226	mannosyl binding site [chemical binding]; other site
331111005227	Fimbrial protein; Region: Fimbrial; pfam00419
331111005228	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
331111005229	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
331111005230	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
331111005231	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
331111005232	Type II secretory pathway, component PulD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulD; COG1450
331111005233	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
331111005234	Zonular occludens toxin (Zot); Region: Zot; cl17485
331111005235	Phage Coat Protein A; Region: Phage_Coat_A; pfam05357
331111005236	DNA replication initiation protein; Region: PHA00202
331111005237	Replication initiation factor; Region: Rep_trans; pfam02486
331111005238	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
331111005239	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111005240	non-specific DNA binding site [nucleotide binding]; other site
331111005241	salt bridge; other site
331111005242	sequence-specific DNA binding site [nucleotide binding]; other site
331111005243	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
331111005244	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
331111005245	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
331111005246	Autotransporter beta-domain; Region: Autotransporter; pfam03797
331111005247	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
331111005248	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
331111005249	putative N- and C-terminal domain interface [polypeptide binding]; other site
331111005250	putative active site [active]
331111005251	putative MgATP binding site [chemical binding]; other site
331111005252	catalytic site [active]
331111005253	metal binding site [ion binding]; metal-binding site
331111005254	putative carbohydrate binding site [chemical binding]; other site
331111005255	transcriptional regulator LsrR; Provisional; Region: PRK15418
331111005256	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
331111005257	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
331111005258	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
331111005259	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
331111005260	Walker A/P-loop; other site
331111005261	ATP binding site [chemical binding]; other site
331111005262	Q-loop/lid; other site
331111005263	ABC transporter signature motif; other site
331111005264	Walker B; other site
331111005265	D-loop; other site
331111005266	H-loop/switch region; other site
331111005267	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111005268	Walker A/P-loop; other site
331111005269	ATP binding site [chemical binding]; other site
331111005270	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
331111005271	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
331111005272	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
331111005273	ligand binding site [chemical binding]; other site
331111005274	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
331111005275	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
331111005276	putative active site; other site
331111005277	catalytic residue [active]
331111005278	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
331111005279	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111005280	S-adenosylmethionine binding site [chemical binding]; other site
331111005281	Predicted membrane protein [Function unknown]; Region: COG3781
331111005282	altronate oxidoreductase; Provisional; Region: PRK03643
331111005283	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
331111005284	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
331111005285	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
331111005286	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111005287	metal binding site [ion binding]; metal-binding site
331111005288	active site
331111005289	I-site; other site
331111005290	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
331111005291	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
331111005292	glutaminase; Provisional; Region: PRK00971
331111005293	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
331111005294	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
331111005295	NAD(P) binding site [chemical binding]; other site
331111005296	catalytic residues [active]
331111005297	Transcriptional regulator [Transcription]; Region: LysR; COG0583
331111005298	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111005299	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
331111005300	putative dimerization interface [polypeptide binding]; other site
331111005301	putative arabinose transporter; Provisional; Region: PRK03545
331111005302	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111005303	putative substrate translocation pore; other site
331111005304	inner membrane protein; Provisional; Region: PRK10995
331111005305	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
331111005306	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
331111005307	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
331111005308	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111005309	hypothetical protein; Provisional; Region: PRK10106
331111005310	6-phospho-beta-glucosidase; Reviewed; Region: celA; PRK09589
331111005311	beta-galactosidase; Region: BGL; TIGR03356
331111005312	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
331111005313	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
331111005314	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
331111005315	trimer interface; other site
331111005316	sugar binding site [chemical binding]; other site
331111005317	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
331111005318	active site
331111005319	methionine cluster; other site
331111005320	phosphorylation site [posttranslational modification]
331111005321	metal binding site [ion binding]; metal-binding site
331111005322	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
331111005323	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
331111005324	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
331111005325	active site
331111005326	P-loop; other site
331111005327	phosphorylation site [posttranslational modification]
331111005328	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
331111005329	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111005330	DNA-binding site [nucleotide binding]; DNA binding site
331111005331	UTRA domain; Region: UTRA; pfam07702
331111005332	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
331111005333	EamA-like transporter family; Region: EamA; pfam00892
331111005334	EamA-like transporter family; Region: EamA; pfam00892
331111005335	putative transporter; Provisional; Region: PRK10054
331111005336	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111005337	putative substrate translocation pore; other site
331111005338	diguanylate cyclase; Provisional; Region: PRK09894
331111005339	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
331111005340	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111005341	metal binding site [ion binding]; metal-binding site
331111005342	active site
331111005343	I-site; other site
331111005344	hypothetical protein; Provisional; Region: PRK10053
331111005345	hypothetical protein; Validated; Region: PRK03657
331111005346	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
331111005347	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
331111005348	active site
331111005349	Zn binding site [ion binding]; other site
331111005350	malonic semialdehyde reductase; Provisional; Region: PRK10538
331111005351	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
331111005352	putative NAD(P) binding site [chemical binding]; other site
331111005353	homodimer interface [polypeptide binding]; other site
331111005354	homotetramer interface [polypeptide binding]; other site
331111005355	active site
331111005356	Transcriptional regulators [Transcription]; Region: GntR; COG1802
331111005357	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111005358	DNA-binding site [nucleotide binding]; DNA binding site
331111005359	FCD domain; Region: FCD; pfam07729
331111005360	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
331111005361	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
331111005362	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
331111005363	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
331111005364	metabolite-proton symporter; Region: 2A0106; TIGR00883
331111005365	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111005366	putative substrate translocation pore; other site
331111005367	multiple promoter invertase; Provisional; Region: mpi; PRK13413
331111005368	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
331111005369	catalytic residues [active]
331111005370	catalytic nucleophile [active]
331111005371	Presynaptic Site I dimer interface [polypeptide binding]; other site
331111005372	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
331111005373	Synaptic Flat tetramer interface [polypeptide binding]; other site
331111005374	Synaptic Site I dimer interface [polypeptide binding]; other site
331111005375	DNA binding site [nucleotide binding]
331111005376	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
331111005377	DNA-binding interface [nucleotide binding]; DNA binding site
331111005378	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
331111005379	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
331111005380	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
331111005381	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
331111005382	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111005383	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
331111005384	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
331111005385	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111005386	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111005387	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111005388	Transposase; Region: HTH_Tnp_1; pfam01527
331111005389	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111005390	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
331111005391	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111005392	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
331111005393	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
331111005394	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111005395	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111005396	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111005397	Transposase; Region: HTH_Tnp_1; pfam01527
331111005398	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111005399	Lysis protein S; Region: Lysis_S; pfam04971
331111005400	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
331111005401	DNA-binding site [nucleotide binding]; DNA binding site
331111005402	RNA-binding motif; other site
331111005403	Antitermination protein; Region: Antiterm; pfam03589
331111005404	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
331111005405	DnaJ central domain; Region: DnaJ_CXXCXGXG; pfam00684
331111005406	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
331111005407	Protein of unknown function (DUF968); Region: DUF968; pfam06147
331111005408	AIPR protein; Region: AIPR; pfam10592
331111005409	Transposase; Region: HTH_Tnp_1; cl17663
331111005410	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111005411	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
331111005412	primosomal protein DnaI; Provisional; Region: PRK02854
331111005413	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
331111005414	DNA-binding transcriptional regulator DicC; Provisional; Region: PRK09744
331111005415	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
331111005416	DicB protein; Region: DicB; pfam05358
331111005417	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
331111005418	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
331111005419	active site
331111005420	catalytic site [active]
331111005421	substrate binding site [chemical binding]; other site
331111005422	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
331111005423	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
331111005424	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
331111005425	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
331111005426	Int/Topo IB signature motif; other site
331111005427	putative oxidoreductase; Provisional; Region: PRK10083
331111005428	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
331111005429	putative NAD(P) binding site [chemical binding]; other site
331111005430	catalytic Zn binding site [ion binding]; other site
331111005431	structural Zn binding site [ion binding]; other site
331111005432	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
331111005433	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
331111005434	putative active site pocket [active]
331111005435	putative metal binding site [ion binding]; other site
331111005436	hypothetical protein; Provisional; Region: PRK02237
331111005437	hypothetical protein; Provisional; Region: PRK13659
331111005438	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
331111005439	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
331111005440	Coenzyme A binding pocket [chemical binding]; other site
331111005441	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
331111005442	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
331111005443	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
331111005444	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
331111005445	putative [Fe4-S4] binding site [ion binding]; other site
331111005446	putative molybdopterin cofactor binding site [chemical binding]; other site
331111005447	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
331111005448	putative molybdopterin cofactor binding site; other site
331111005449	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
331111005450	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
331111005451	putative [Fe4-S4] binding site [ion binding]; other site
331111005452	putative molybdopterin cofactor binding site [chemical binding]; other site
331111005453	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
331111005454	putative molybdopterin cofactor binding site; other site
331111005455	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
331111005456	4Fe-4S binding domain; Region: Fer4; cl02805
331111005457	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
331111005458	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
331111005459	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
331111005460	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
331111005461	Cl- selectivity filter; other site
331111005462	Cl- binding residues [ion binding]; other site
331111005463	pore gating glutamate residue; other site
331111005464	dimer interface [polypeptide binding]; other site
331111005465	putative dithiobiotin synthetase; Provisional; Region: PRK12374
331111005466	AAA domain; Region: AAA_26; pfam13500
331111005467	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
331111005468	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
331111005469	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
331111005470	nucleotide binding site [chemical binding]; other site
331111005471	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
331111005472	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111005473	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
331111005474	dimerization interface [polypeptide binding]; other site
331111005475	substrate binding pocket [chemical binding]; other site
331111005476	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
331111005477	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111005478	putative substrate translocation pore; other site
331111005479	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
331111005480	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
331111005481	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
331111005482	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
331111005483	Domain of unknown function DUF20; Region: UPF0118; pfam01594
331111005484	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
331111005485	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
331111005486	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
331111005487	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
331111005488	ligand binding site [chemical binding]; other site
331111005489	homodimer interface [polypeptide binding]; other site
331111005490	NAD(P) binding site [chemical binding]; other site
331111005491	trimer interface B [polypeptide binding]; other site
331111005492	trimer interface A [polypeptide binding]; other site
331111005493	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
331111005494	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
331111005495	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
331111005496	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
331111005497	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
331111005498	Spore germination protein; Region: Spore_permease; cl17796
331111005499	dihydromonapterin reductase; Provisional; Region: PRK06483
331111005500	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
331111005501	NADP binding site [chemical binding]; other site
331111005502	substrate binding pocket [chemical binding]; other site
331111005503	active site
331111005504	GlpM protein; Region: GlpM; pfam06942
331111005505	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
331111005506	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111005507	active site
331111005508	phosphorylation site [posttranslational modification]
331111005509	intermolecular recognition site; other site
331111005510	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
331111005511	DNA binding site [nucleotide binding]
331111005512	sensor protein RstB; Provisional; Region: PRK10604
331111005513	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
331111005514	dimerization interface [polypeptide binding]; other site
331111005515	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111005516	dimer interface [polypeptide binding]; other site
331111005517	phosphorylation site [posttranslational modification]
331111005518	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111005519	ATP binding site [chemical binding]; other site
331111005520	Mg2+ binding site [ion binding]; other site
331111005521	G-X-G motif; other site
331111005522	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
331111005523	fumarate hydratase; Reviewed; Region: fumC; PRK00485
331111005524	Class II fumarases; Region: Fumarase_classII; cd01362
331111005525	active site
331111005526	tetramer interface [polypeptide binding]; other site
331111005527	fumarate hydratase; Provisional; Region: PRK15389
331111005528	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
331111005529	Fumarase C-terminus; Region: Fumerase_C; pfam05683
331111005530	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
331111005531	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
331111005532	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
331111005533	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
331111005534	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
331111005535	putative outer membrane porin protein; Provisional; Region: PRK11379
331111005536	glucuronide transporter; Provisional; Region: PRK09848
331111005537	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111005538	putative substrate translocation pore; other site
331111005539	beta-D-glucuronidase; Provisional; Region: PRK10150
331111005540	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
331111005541	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
331111005542	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
331111005543	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
331111005544	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
331111005545	7-alpha-hydroxysteroid dehydrogenase; Validated; Region: PRK06113
331111005546	7 alpha-hydroxysteroid dehydrogenase (7 alpha-HSDH), classical (c) SDRs; Region: 7_alpha_HSDH_SDR_c; cd05365
331111005547	NAD binding site [chemical binding]; other site
331111005548	substrate binding site [chemical binding]; other site
331111005549	homotetramer interface [polypeptide binding]; other site
331111005550	homodimer interface [polypeptide binding]; other site
331111005551	active site
331111005552	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
331111005553	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
331111005554	DNA binding site [nucleotide binding]
331111005555	domain linker motif; other site
331111005556	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
331111005557	putative dimerization interface [polypeptide binding]; other site
331111005558	putative ligand binding site [chemical binding]; other site
331111005559	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
331111005560	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
331111005561	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
331111005562	active site turn [active]
331111005563	phosphorylation site [posttranslational modification]
331111005564	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
331111005565	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
331111005566	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111005567	homodimer interface [polypeptide binding]; other site
331111005568	catalytic residue [active]
331111005569	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
331111005570	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
331111005571	active site
331111005572	purine riboside binding site [chemical binding]; other site
331111005573	putative oxidoreductase; Provisional; Region: PRK11579
331111005574	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
331111005575	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
331111005576	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
331111005577	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
331111005578	electron transport complex protein RsxA; Provisional; Region: PRK05151
331111005579	electron transport complex protein RnfB; Provisional; Region: PRK05113
331111005580	Putative Fe-S cluster; Region: FeS; pfam04060
331111005581	4Fe-4S binding domain; Region: Fer4; pfam00037
331111005582	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
331111005583	SLBB domain; Region: SLBB; pfam10531
331111005584	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
331111005585	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
331111005586	electron transport complex protein RnfG; Validated; Region: PRK01908
331111005587	electron transport complex RsxE subunit; Provisional; Region: PRK12405
331111005588	endonuclease III; Provisional; Region: PRK10702
331111005589	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
331111005590	minor groove reading motif; other site
331111005591	helix-hairpin-helix signature motif; other site
331111005592	substrate binding pocket [chemical binding]; other site
331111005593	active site
331111005594	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
331111005595	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
331111005596	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111005597	putative substrate translocation pore; other site
331111005598	POT family; Region: PTR2; pfam00854
331111005599	glutathionine S-transferase; Provisional; Region: PRK10542
331111005600	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
331111005601	C-terminal domain interface [polypeptide binding]; other site
331111005602	GSH binding site (G-site) [chemical binding]; other site
331111005603	dimer interface [polypeptide binding]; other site
331111005604	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
331111005605	N-terminal domain interface [polypeptide binding]; other site
331111005606	dimer interface [polypeptide binding]; other site
331111005607	substrate binding pocket (H-site) [chemical binding]; other site
331111005608	pyridoxamine kinase; Validated; Region: PRK05756
331111005609	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
331111005610	dimer interface [polypeptide binding]; other site
331111005611	pyridoxal binding site [chemical binding]; other site
331111005612	ATP binding site [chemical binding]; other site
331111005613	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
331111005614	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
331111005615	active site
331111005616	HIGH motif; other site
331111005617	dimer interface [polypeptide binding]; other site
331111005618	KMSKS motif; other site
331111005619	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
331111005620	RNA binding surface [nucleotide binding]; other site
331111005621	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
331111005622	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
331111005623	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
331111005624	lysozyme inhibitor; Provisional; Region: PRK11372
331111005625	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
331111005626	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
331111005627	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
331111005628	transcriptional regulator SlyA; Provisional; Region: PRK03573
331111005629	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
331111005630	Protein of unknown function (DUF1656); Region: DUF1656; cl11658
331111005631	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
331111005632	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
331111005633	HlyD family secretion protein; Region: HlyD_3; pfam13437
331111005634	Fusaric acid resistance protein family; Region: FUSC; pfam04632
331111005635	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
331111005636	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
331111005637	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
331111005638	E-class dimer interface [polypeptide binding]; other site
331111005639	P-class dimer interface [polypeptide binding]; other site
331111005640	active site
331111005641	Cu2+ binding site [ion binding]; other site
331111005642	Zn2+ binding site [ion binding]; other site
331111005643	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
331111005644	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
331111005645	active site
331111005646	catalytic tetrad [active]
331111005647	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
331111005648	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
331111005649	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
331111005650	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
331111005651	FMN binding site [chemical binding]; other site
331111005652	active site
331111005653	substrate binding site [chemical binding]; other site
331111005654	catalytic residue [active]
331111005655	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
331111005656	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
331111005657	dimer interface [polypeptide binding]; other site
331111005658	active site
331111005659	metal binding site [ion binding]; metal-binding site
331111005660	glutathione binding site [chemical binding]; other site
331111005661	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
331111005662	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
331111005663	dimer interface [polypeptide binding]; other site
331111005664	catalytic site [active]
331111005665	putative active site [active]
331111005666	putative substrate binding site [chemical binding]; other site
331111005667	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
331111005668	putative ATP-dependent helicase Lhr; Provisional; Region: PRK09751
331111005669	ATP binding site [chemical binding]; other site
331111005670	putative Mg++ binding site [ion binding]; other site
331111005671	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111005672	nucleotide binding region [chemical binding]; other site
331111005673	ATP-binding site [chemical binding]; other site
331111005674	DEAD/H associated; Region: DEAD_assoc; pfam08494
331111005675	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
331111005676	putative GSH binding site [chemical binding]; other site
331111005677	catalytic residues [active]
331111005678	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
331111005679	NlpC/P60 family; Region: NLPC_P60; pfam00877
331111005680	superoxide dismutase; Provisional; Region: PRK10543
331111005681	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
331111005682	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
331111005683	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111005684	Major Facilitator Superfamily; Region: MFS_1; pfam07690
331111005685	putative substrate translocation pore; other site
331111005686	hypothetical protein; Provisional; Region: PRK14756
331111005687	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
331111005688	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
331111005689	DNA binding site [nucleotide binding]
331111005690	domain linker motif; other site
331111005691	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
331111005692	dimerization interface [polypeptide binding]; other site
331111005693	ligand binding site [chemical binding]; other site
331111005694	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
331111005695	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111005696	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
331111005697	dimerization interface [polypeptide binding]; other site
331111005698	putative transporter; Provisional; Region: PRK11043
331111005699	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111005700	putative substrate translocation pore; other site
331111005701	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
331111005702	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
331111005703	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111005704	S-adenosylmethionine binding site [chemical binding]; other site
331111005705	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
331111005706	Lumazine binding domain; Region: Lum_binding; pfam00677
331111005707	Lumazine binding domain; Region: Lum_binding; pfam00677
331111005708	multidrug efflux protein; Reviewed; Region: PRK01766
331111005709	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
331111005710	cation binding site [ion binding]; other site
331111005711	hypothetical protein; Provisional; Region: PRK09945
331111005712	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
331111005713	putative monooxygenase; Provisional; Region: PRK11118
331111005714	hypothetical protein; Provisional; Region: PRK09946
331111005715	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
331111005716	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
331111005717	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
331111005718	hypothetical protein; Provisional; Region: PRK09947
331111005719	putative oxidoreductase; Provisional; Region: PRK09849
331111005720	Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; pfam02730
331111005721	Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314
331111005722	hypothetical protein; Provisional; Region: PRK09898
331111005723	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
331111005724	hypothetical protein; Provisional; Region: PRK10292
331111005725	pyruvate kinase; Provisional; Region: PRK09206
331111005726	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
331111005727	domain interfaces; other site
331111005728	active site
331111005729	murein lipoprotein; Provisional; Region: PRK15396
331111005730	L,D-transpeptidase; Provisional; Region: PRK10190
331111005731	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
331111005732	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
331111005733	cysteine desufuration protein SufE; Provisional; Region: PRK09296
331111005734	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
331111005735	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
331111005736	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
331111005737	catalytic residue [active]
331111005738	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
331111005739	FeS assembly protein SufD; Region: sufD; TIGR01981
331111005740	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
331111005741	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
331111005742	Walker A/P-loop; other site
331111005743	ATP binding site [chemical binding]; other site
331111005744	Q-loop/lid; other site
331111005745	ABC transporter signature motif; other site
331111005746	Walker B; other site
331111005747	D-loop; other site
331111005748	H-loop/switch region; other site
331111005749	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
331111005750	putative ABC transporter; Region: ycf24; CHL00085
331111005751	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
331111005752	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
331111005753	CoenzymeA binding site [chemical binding]; other site
331111005754	subunit interaction site [polypeptide binding]; other site
331111005755	PHB binding site; other site
331111005756	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
331111005757	FAD binding domain; Region: FAD_binding_4; pfam01565
331111005758	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
331111005759	putative inner membrane protein; Provisional; Region: PRK10983
331111005760	Domain of unknown function DUF20; Region: UPF0118; pfam01594
331111005761	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
331111005762	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111005763	Major Facilitator Superfamily; Region: MFS_1; pfam07690
331111005764	putative substrate translocation pore; other site
331111005765	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111005766	putative substrate translocation pore; other site
331111005767	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
331111005768	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
331111005769	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
331111005770	shikimate binding site; other site
331111005771	NAD(P) binding site [chemical binding]; other site
331111005772	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
331111005773	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
331111005774	active site
331111005775	catalytic residue [active]
331111005776	dimer interface [polypeptide binding]; other site
331111005777	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
331111005778	Coenzyme A transferase; Region: CoA_trans; smart00882
331111005779	Coenzyme A transferase; Region: CoA_trans; cl17247
331111005780	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
331111005781	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
331111005782	active site
331111005783	Cupin domain; Region: Cupin_2; pfam07883
331111005784	Winged helix DNA-binding domain (DUF1495); Region: DUF1495; cl01336
331111005785	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
331111005786	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111005787	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
331111005788	Ligand binding site [chemical binding]; other site
331111005789	Electron transfer flavoprotein domain; Region: ETF; pfam01012
331111005790	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
331111005791	Electron transfer flavoprotein domain; Region: ETF; smart00893
331111005792	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
331111005793	oxidoreductase; Provisional; Region: PRK10015
331111005794	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
331111005795	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
331111005796	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
331111005797	acyl-activating enzyme (AAE) consensus motif; other site
331111005798	putative AMP binding site [chemical binding]; other site
331111005799	putative active site [active]
331111005800	putative CoA binding site [chemical binding]; other site
331111005801	phosphoenolpyruvate synthase; Validated; Region: PRK06464
331111005802	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
331111005803	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
331111005804	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
331111005805	PEP synthetase regulatory protein; Provisional; Region: PRK05339
331111005806	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
331111005807	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
331111005808	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
331111005809	Uncharacterized conserved protein [Function unknown]; Region: COG0397
331111005810	hypothetical protein; Validated; Region: PRK00029
331111005811	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
331111005812	NlpC/P60 family; Region: NLPC_P60; pfam00877
331111005813	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
331111005814	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
331111005815	Walker A/P-loop; other site
331111005816	ATP binding site [chemical binding]; other site
331111005817	Q-loop/lid; other site
331111005818	ABC transporter signature motif; other site
331111005819	Walker B; other site
331111005820	D-loop; other site
331111005821	H-loop/switch region; other site
331111005822	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
331111005823	catalytic residues [active]
331111005824	dimer interface [polypeptide binding]; other site
331111005825	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
331111005826	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
331111005827	ABC-ATPase subunit  interface; other site
331111005828	dimer interface [polypeptide binding]; other site
331111005829	putative PBP binding regions; other site
331111005830	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
331111005831	IHF dimer interface [polypeptide binding]; other site
331111005832	IHF - DNA interface [nucleotide binding]; other site
331111005833	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
331111005834	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
331111005835	putative tRNA-binding site [nucleotide binding]; other site
331111005836	B3/4 domain; Region: B3_4; pfam03483
331111005837	tRNA synthetase B5 domain; Region: B5; smart00874
331111005838	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
331111005839	dimer interface [polypeptide binding]; other site
331111005840	motif 1; other site
331111005841	motif 3; other site
331111005842	motif 2; other site
331111005843	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
331111005844	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
331111005845	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
331111005846	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
331111005847	dimer interface [polypeptide binding]; other site
331111005848	motif 1; other site
331111005849	active site
331111005850	motif 2; other site
331111005851	motif 3; other site
331111005852	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
331111005853	23S rRNA binding site [nucleotide binding]; other site
331111005854	L21 binding site [polypeptide binding]; other site
331111005855	L13 binding site [polypeptide binding]; other site
331111005856	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
331111005857	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
331111005858	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
331111005859	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
331111005860	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
331111005861	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
331111005862	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
331111005863	active site
331111005864	dimer interface [polypeptide binding]; other site
331111005865	motif 1; other site
331111005866	motif 2; other site
331111005867	motif 3; other site
331111005868	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
331111005869	anticodon binding site; other site
331111005870	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
331111005871	6-phosphofructokinase 2; Provisional; Region: PRK10294
331111005872	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
331111005873	putative substrate binding site [chemical binding]; other site
331111005874	putative ATP binding site [chemical binding]; other site
331111005875	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
331111005876	Phosphotransferase enzyme family; Region: APH; pfam01636
331111005877	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
331111005878	active site
331111005879	ATP binding site [chemical binding]; other site
331111005880	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
331111005881	YniB-like protein; Region: YniB; pfam14002
331111005882	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
331111005883	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
331111005884	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111005885	motif II; other site
331111005886	inner membrane protein; Provisional; Region: PRK11648
331111005887	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
331111005888	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
331111005889	cell division modulator; Provisional; Region: PRK10113
331111005890	hydroperoxidase II; Provisional; Region: katE; PRK11249
331111005891	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
331111005892	tetramer interface [polypeptide binding]; other site
331111005893	heme binding pocket [chemical binding]; other site
331111005894	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
331111005895	domain interactions; other site
331111005896	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
331111005897	putative active site [active]
331111005898	YdjC motif; other site
331111005899	Mg binding site [ion binding]; other site
331111005900	putative homodimer interface [polypeptide binding]; other site
331111005901	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
331111005902	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
331111005903	NAD binding site [chemical binding]; other site
331111005904	sugar binding site [chemical binding]; other site
331111005905	divalent metal binding site [ion binding]; other site
331111005906	tetramer (dimer of dimers) interface [polypeptide binding]; other site
331111005907	dimer interface [polypeptide binding]; other site
331111005908	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
331111005909	Cupin domain; Region: Cupin_2; pfam07883
331111005910	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111005911	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
331111005912	methionine cluster; other site
331111005913	active site
331111005914	phosphorylation site [posttranslational modification]
331111005915	metal binding site [ion binding]; metal-binding site
331111005916	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
331111005917	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
331111005918	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
331111005919	active site
331111005920	P-loop; other site
331111005921	phosphorylation site [posttranslational modification]
331111005922	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
331111005923	NAD+ synthetase; Region: nadE; TIGR00552
331111005924	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
331111005925	homodimer interface [polypeptide binding]; other site
331111005926	NAD binding pocket [chemical binding]; other site
331111005927	ATP binding pocket [chemical binding]; other site
331111005928	Mg binding site [ion binding]; other site
331111005929	active-site loop [active]
331111005930	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
331111005931	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
331111005932	GIY-YIG motif/motif A; other site
331111005933	active site
331111005934	catalytic site [active]
331111005935	putative DNA binding site [nucleotide binding]; other site
331111005936	metal binding site [ion binding]; metal-binding site
331111005937	hypothetical protein; Provisional; Region: PRK11396
331111005938	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
331111005939	dimer interface [polypeptide binding]; other site
331111005940	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
331111005941	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
331111005942	putative active site [active]
331111005943	Zn binding site [ion binding]; other site
331111005944	succinylarginine dihydrolase; Provisional; Region: PRK13281
331111005945	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
331111005946	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
331111005947	NAD(P) binding site [chemical binding]; other site
331111005948	catalytic residues [active]
331111005949	arginine succinyltransferase; Provisional; Region: PRK10456
331111005950	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
331111005951	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
331111005952	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
331111005953	inhibitor-cofactor binding pocket; inhibition site
331111005954	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111005955	catalytic residue [active]
331111005956	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
331111005957	putative catalytic site [active]
331111005958	putative phosphate binding site [ion binding]; other site
331111005959	active site
331111005960	metal binding site A [ion binding]; metal-binding site
331111005961	DNA binding site [nucleotide binding]
331111005962	putative AP binding site [nucleotide binding]; other site
331111005963	putative metal binding site B [ion binding]; other site
331111005964	Uncharacterized conserved protein [Function unknown]; Region: COG0398
331111005965	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
331111005966	Uncharacterized conserved protein [Function unknown]; Region: COG0398
331111005967	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
331111005968	Uncharacterized conserved protein [Function unknown]; Region: COG2128
331111005969	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
331111005970	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
331111005971	hypothetical protein; Provisional; Region: PRK11622
331111005972	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
331111005973	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111005974	dimer interface [polypeptide binding]; other site
331111005975	conserved gate region; other site
331111005976	putative PBP binding loops; other site
331111005977	ABC-ATPase subunit interface; other site
331111005978	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
331111005979	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111005980	Walker A/P-loop; other site
331111005981	ATP binding site [chemical binding]; other site
331111005982	Q-loop/lid; other site
331111005983	ABC transporter signature motif; other site
331111005984	Walker B; other site
331111005985	D-loop; other site
331111005986	H-loop/switch region; other site
331111005987	Rhodanese Homology Domain; Region: RHOD; smart00450
331111005988	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
331111005989	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
331111005990	active site residue [active]
331111005991	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
331111005992	active site residue [active]
331111005993	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
331111005994	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
331111005995	active site
331111005996	8-oxo-dGMP binding site [chemical binding]; other site
331111005997	nudix motif; other site
331111005998	metal binding site [ion binding]; metal-binding site
331111005999	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
331111006000	glutamate dehydrogenase; Provisional; Region: PRK09414
331111006001	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
331111006002	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
331111006003	NAD(P) binding site [chemical binding]; other site
331111006004	hypothetical protein; Provisional; Region: PRK11380
331111006005	DNA topoisomerase III; Provisional; Region: PRK07726
331111006006	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
331111006007	active site
331111006008	putative interdomain interaction site [polypeptide binding]; other site
331111006009	putative metal-binding site [ion binding]; other site
331111006010	putative nucleotide binding site [chemical binding]; other site
331111006011	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
331111006012	domain I; other site
331111006013	DNA binding groove [nucleotide binding]
331111006014	phosphate binding site [ion binding]; other site
331111006015	domain II; other site
331111006016	domain III; other site
331111006017	nucleotide binding site [chemical binding]; other site
331111006018	catalytic site [active]
331111006019	domain IV; other site
331111006020	selenophosphate synthetase; Provisional; Region: PRK00943
331111006021	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
331111006022	dimerization interface [polypeptide binding]; other site
331111006023	putative ATP binding site [chemical binding]; other site
331111006024	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
331111006025	putative FMN binding site [chemical binding]; other site
331111006026	protease 4; Provisional; Region: PRK10949
331111006027	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
331111006028	tandem repeat interface [polypeptide binding]; other site
331111006029	oligomer interface [polypeptide binding]; other site
331111006030	active site residues [active]
331111006031	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
331111006032	tandem repeat interface [polypeptide binding]; other site
331111006033	oligomer interface [polypeptide binding]; other site
331111006034	active site residues [active]
331111006035	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
331111006036	active site
331111006037	homodimer interface [polypeptide binding]; other site
331111006038	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
331111006039	Isochorismatase family; Region: Isochorismatase; pfam00857
331111006040	catalytic triad [active]
331111006041	metal binding site [ion binding]; metal-binding site
331111006042	conserved cis-peptide bond; other site
331111006043	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
331111006044	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111006045	putative substrate translocation pore; other site
331111006046	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111006047	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
331111006048	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
331111006049	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
331111006050	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
331111006051	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
331111006052	active site
331111006053	catalytic tetrad [active]
331111006054	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
331111006055	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
331111006056	substrate binding site [chemical binding]; other site
331111006057	ATP binding site [chemical binding]; other site
331111006058	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
331111006059	intersubunit interface [polypeptide binding]; other site
331111006060	active site
331111006061	zinc binding site [ion binding]; other site
331111006062	Na+ binding site [ion binding]; other site
331111006063	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
331111006064	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
331111006065	inhibitor binding site; inhibition site
331111006066	catalytic Zn binding site [ion binding]; other site
331111006067	structural Zn binding site [ion binding]; other site
331111006068	NADP binding site [chemical binding]; other site
331111006069	tetramer interface [polypeptide binding]; other site
331111006070	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111006071	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111006072	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
331111006073	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
331111006074	putative NAD(P) binding site [chemical binding]; other site
331111006075	catalytic Zn binding site [ion binding]; other site
331111006076	structural Zn binding site [ion binding]; other site
331111006077	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
331111006078	methionine sulfoxide reductase B; Provisional; Region: PRK00222
331111006079	SelR domain; Region: SelR; pfam01641
331111006080	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
331111006081	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
331111006082	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
331111006083	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
331111006084	active site
331111006085	phosphate binding residues; other site
331111006086	catalytic residues [active]
331111006087	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
331111006088	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
331111006089	active site
331111006090	catalytic tetrad [active]
331111006091	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
331111006092	PrkA family serine protein kinase; Provisional; Region: PRK15455
331111006093	AAA ATPase domain; Region: AAA_16; pfam13191
331111006094	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
331111006095	hypothetical protein; Provisional; Region: PRK05325
331111006096	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
331111006097	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111006098	metal binding site [ion binding]; metal-binding site
331111006099	active site
331111006100	I-site; other site
331111006101	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
331111006102	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111006103	metal binding site [ion binding]; metal-binding site
331111006104	active site
331111006105	I-site; other site
331111006106	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
331111006107	putative deacylase active site [active]
331111006108	Predicted membrane protein [Function unknown]; Region: COG2707
331111006109	cyanate transporter; Region: CynX; TIGR00896
331111006110	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111006111	putative substrate translocation pore; other site
331111006112	Uncharacterized conserved protein [Function unknown]; Region: COG3189
331111006113	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
331111006114	Domain of unknown function (DUF333); Region: DUF333; pfam03891
331111006115	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
331111006116	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
331111006117	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
331111006118	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111006119	metal binding site [ion binding]; metal-binding site
331111006120	active site
331111006121	I-site; other site
331111006122	hypothetical protein; Provisional; Region: PRK10457
331111006123	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
331111006124	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
331111006125	Probable transposase; Region: OrfB_IS605; pfam01385
331111006126	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
331111006127	Transposase IS200 like; Region: Y1_Tnp; pfam01797
331111006128	leucine export protein LeuE; Provisional; Region: PRK10958
331111006129	transcriptional activator TtdR; Provisional; Region: PRK09801
331111006130	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111006131	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
331111006132	putative effector binding pocket; other site
331111006133	putative dimerization interface [polypeptide binding]; other site
331111006134	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
331111006135	tartrate dehydrogenase; Region: TTC; TIGR02089
331111006136	putative transporter; Provisional; Region: PRK09950
331111006137	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
331111006138	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
331111006139	[2Fe-2S] cluster binding site [ion binding]; other site
331111006140	C-terminal catalytic domain of the oxygenase alpha subunit of an uncharacterized subgroup of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C_2; cd08886
331111006141	putative alpha subunit interface [polypeptide binding]; other site
331111006142	putative active site [active]
331111006143	putative substrate binding site [chemical binding]; other site
331111006144	Fe binding site [ion binding]; other site
331111006145	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
331111006146	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
331111006147	FMN-binding pocket [chemical binding]; other site
331111006148	flavin binding motif; other site
331111006149	phosphate binding motif [ion binding]; other site
331111006150	beta-alpha-beta structure motif; other site
331111006151	NAD binding pocket [chemical binding]; other site
331111006152	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
331111006153	catalytic loop [active]
331111006154	iron binding site [ion binding]; other site
331111006155	ribonuclease D; Provisional; Region: PRK10829
331111006156	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
331111006157	catalytic site [active]
331111006158	putative active site [active]
331111006159	putative substrate binding site [chemical binding]; other site
331111006160	Helicase and RNase D C-terminal; Region: HRDC; smart00341
331111006161	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
331111006162	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
331111006163	acyl-activating enzyme (AAE) consensus motif; other site
331111006164	putative AMP binding site [chemical binding]; other site
331111006165	putative active site [active]
331111006166	putative CoA binding site [chemical binding]; other site
331111006167	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
331111006168	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
331111006169	Glycoprotease family; Region: Peptidase_M22; pfam00814
331111006170	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
331111006171	DEAD/DEAH box helicase; Region: DEAD; pfam00270
331111006172	DEAD_2; Region: DEAD_2; pfam06733
331111006173	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
331111006174	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
331111006175	homotrimer interaction site [polypeptide binding]; other site
331111006176	putative active site [active]
331111006177	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
331111006178	hypothetical protein; Provisional; Region: PRK05114
331111006179	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
331111006180	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
331111006181	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
331111006182	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
331111006183	putative active site [active]
331111006184	putative CoA binding site [chemical binding]; other site
331111006185	nudix motif; other site
331111006186	metal binding site [ion binding]; metal-binding site
331111006187	L-serine deaminase; Provisional; Region: PRK15023
331111006188	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
331111006189	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
331111006190	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
331111006191	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
331111006192	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
331111006193	Transporter associated domain; Region: CorC_HlyC; smart01091
331111006194	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
331111006195	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
331111006196	active pocket/dimerization site; other site
331111006197	active site
331111006198	phosphorylation site [posttranslational modification]
331111006199	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
331111006200	active site
331111006201	phosphorylation site [posttranslational modification]
331111006202	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
331111006203	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
331111006204	Predicted membrane protein [Function unknown]; Region: COG4811
331111006205	hypothetical protein; Provisional; Region: PRK11469
331111006206	Domain of unknown function DUF; Region: DUF204; pfam02659
331111006207	Domain of unknown function DUF; Region: DUF204; pfam02659
331111006208	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
331111006209	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111006210	S-adenosylmethionine binding site [chemical binding]; other site
331111006211	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
331111006212	DNA-binding site [nucleotide binding]; DNA binding site
331111006213	RNA-binding motif; other site
331111006214	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
331111006215	YebO-like protein; Region: YebO; pfam13974
331111006216	PhoPQ regulatory protein; Provisional; Region: PRK10299
331111006217	YobH-like protein; Region: YobH; pfam13996
331111006218	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
331111006219	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
331111006220	dimerization interface [polypeptide binding]; other site
331111006221	putative Zn2+ binding site [ion binding]; other site
331111006222	putative DNA binding site [nucleotide binding]; other site
331111006223	Bacterial transcriptional regulator; Region: IclR; pfam01614
331111006224	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111006225	Major Facilitator Superfamily; Region: MFS_1; pfam07690
331111006226	putative substrate translocation pore; other site
331111006227	Predicted integral membrane protein [Function unknown]; Region: COG5521
331111006228	heat shock protein HtpX; Provisional; Region: PRK05457
331111006229	carboxy-terminal protease; Provisional; Region: PRK11186
331111006230	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
331111006231	protein binding site [polypeptide binding]; other site
331111006232	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
331111006233	Catalytic dyad [active]
331111006234	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
331111006235	ProP expression regulator; Provisional; Region: PRK04950
331111006236	ProQ/FINO family; Region: ProQ; pfam04352
331111006237	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
331111006238	GAF domain; Region: GAF_2; pfam13185
331111006239	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
331111006240	Paraquat-inducible protein A; Region: PqiA; pfam04403
331111006241	Paraquat-inducible protein A; Region: PqiA; pfam04403
331111006242	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
331111006243	mce related protein; Region: MCE; pfam02470
331111006244	mce related protein; Region: MCE; pfam02470
331111006245	mce related protein; Region: MCE; pfam02470
331111006246	mce related protein; Region: MCE; pfam02470
331111006247	mce related protein; Region: MCE; pfam02470
331111006248	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
331111006249	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111006250	S-adenosylmethionine binding site [chemical binding]; other site
331111006251	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
331111006252	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
331111006253	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
331111006254	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
331111006255	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
331111006256	active site
331111006257	metal binding site [ion binding]; metal-binding site
331111006258	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
331111006259	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
331111006260	hypothetical protein; Provisional; Region: PRK10301
331111006261	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
331111006262	Predicted amidohydrolase [General function prediction only]; Region: COG0388
331111006263	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
331111006264	exodeoxyribonuclease X; Provisional; Region: PRK07983
331111006265	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
331111006266	active site
331111006267	catalytic site [active]
331111006268	substrate binding site [chemical binding]; other site
331111006269	protease 2; Provisional; Region: PRK10115
331111006270	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
331111006271	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
331111006272	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
331111006273	putative metal binding site [ion binding]; other site
331111006274	hypothetical protein; Provisional; Region: PRK13680
331111006275	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
331111006276	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
331111006277	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
331111006278	ATP-grasp domain; Region: ATP-grasp; pfam02222
331111006279	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
331111006280	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
331111006281	active site
331111006282	intersubunit interface [polypeptide binding]; other site
331111006283	catalytic residue [active]
331111006284	phosphogluconate dehydratase; Validated; Region: PRK09054
331111006285	6-phosphogluconate dehydratase; Region: edd; TIGR01196
331111006286	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
331111006287	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
331111006288	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
331111006289	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
331111006290	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
331111006291	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
331111006292	putative active site [active]
331111006293	pyruvate kinase; Provisional; Region: PRK05826
331111006294	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
331111006295	domain interfaces; other site
331111006296	active site
331111006297	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
331111006298	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
331111006299	putative acyl-acceptor binding pocket; other site
331111006300	putative peptidase; Provisional; Region: PRK11649
331111006301	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
331111006302	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
331111006303	Peptidase family M23; Region: Peptidase_M23; pfam01551
331111006304	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
331111006305	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
331111006306	metal binding site [ion binding]; metal-binding site
331111006307	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
331111006308	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
331111006309	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
331111006310	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
331111006311	ABC-ATPase subunit  interface; other site
331111006312	dimer interface [polypeptide binding]; other site
331111006313	putative PBP binding regions; other site
331111006314	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
331111006315	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111006316	Walker A motif; other site
331111006317	ATP binding site [chemical binding]; other site
331111006318	Walker B motif; other site
331111006319	arginine finger; other site
331111006320	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
331111006321	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
331111006322	RuvA N terminal domain; Region: RuvA_N; pfam01330
331111006323	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
331111006324	hypothetical protein; Provisional; Region: PRK11470
331111006325	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
331111006326	active site
331111006327	putative DNA-binding cleft [nucleotide binding]; other site
331111006328	dimer interface [polypeptide binding]; other site
331111006329	hypothetical protein; Validated; Region: PRK00110
331111006330	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
331111006331	nudix motif; other site
331111006332	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
331111006333	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
331111006334	dimer interface [polypeptide binding]; other site
331111006335	anticodon binding site; other site
331111006336	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
331111006337	homodimer interface [polypeptide binding]; other site
331111006338	motif 1; other site
331111006339	active site
331111006340	motif 2; other site
331111006341	GAD domain; Region: GAD; pfam02938
331111006342	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
331111006343	motif 3; other site
331111006344	Isochorismatase family; Region: Isochorismatase; pfam00857
331111006345	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
331111006346	catalytic triad [active]
331111006347	conserved cis-peptide bond; other site
331111006348	hypothetical protein; Provisional; Region: PRK10302
331111006349	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
331111006350	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111006351	S-adenosylmethionine binding site [chemical binding]; other site
331111006352	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111006353	S-adenosylmethionine binding site [chemical binding]; other site
331111006354	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
331111006355	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
331111006356	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
331111006357	molybdopterin cofactor binding site [chemical binding]; other site
331111006358	substrate binding site [chemical binding]; other site
331111006359	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
331111006360	molybdopterin cofactor binding site; other site
331111006361	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
331111006362	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
331111006363	copper homeostasis protein CutC; Provisional; Region: PRK11572
331111006364	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
331111006365	putative metal binding site [ion binding]; other site
331111006366	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
331111006367	arginyl-tRNA synthetase; Region: argS; TIGR00456
331111006368	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
331111006369	active site
331111006370	HIGH motif; other site
331111006371	KMSK motif region; other site
331111006372	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
331111006373	tRNA binding surface [nucleotide binding]; other site
331111006374	anticodon binding site; other site
331111006375	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
331111006376	Flagellar protein FlhE; Region: FlhE; pfam06366
331111006377	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
331111006378	FHIPEP family; Region: FHIPEP; pfam00771
331111006379	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
331111006380	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
331111006381	chemotaxis regulator CheZ; Provisional; Region: PRK11166
331111006382	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
331111006383	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111006384	active site
331111006385	phosphorylation site [posttranslational modification]
331111006386	intermolecular recognition site; other site
331111006387	dimerization interface [polypeptide binding]; other site
331111006388	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
331111006389	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111006390	active site
331111006391	phosphorylation site [posttranslational modification]
331111006392	intermolecular recognition site; other site
331111006393	dimerization interface [polypeptide binding]; other site
331111006394	CheB methylesterase; Region: CheB_methylest; pfam01339
331111006395	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
331111006396	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
331111006397	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111006398	S-adenosylmethionine binding site [chemical binding]; other site
331111006399	methyl-accepting protein IV; Provisional; Region: PRK09793
331111006400	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
331111006401	dimer interface [polypeptide binding]; other site
331111006402	ligand binding site [chemical binding]; other site
331111006403	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
331111006404	dimerization interface [polypeptide binding]; other site
331111006405	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
331111006406	dimer interface [polypeptide binding]; other site
331111006407	putative CheW interface [polypeptide binding]; other site
331111006408	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
331111006409	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
331111006410	dimer interface [polypeptide binding]; other site
331111006411	ligand binding site [chemical binding]; other site
331111006412	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
331111006413	dimerization interface [polypeptide binding]; other site
331111006414	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
331111006415	dimer interface [polypeptide binding]; other site
331111006416	putative CheW interface [polypeptide binding]; other site
331111006417	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
331111006418	putative CheA interaction surface; other site
331111006419	chemotaxis protein CheA; Provisional; Region: PRK10547
331111006420	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
331111006421	putative binding surface; other site
331111006422	active site
331111006423	CheY binding; Region: CheY-binding; pfam09078
331111006424	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
331111006425	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111006426	ATP binding site [chemical binding]; other site
331111006427	Mg2+ binding site [ion binding]; other site
331111006428	G-X-G motif; other site
331111006429	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
331111006430	flagellar motor protein MotB; Validated; Region: motB; PRK09041
331111006431	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
331111006432	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
331111006433	ligand binding site [chemical binding]; other site
331111006434	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
331111006435	flagellar motor protein MotA; Validated; Region: PRK09110
331111006436	transcriptional activator FlhC; Provisional; Region: PRK12722
331111006437	transcriptional activator FlhD; Provisional; Region: PRK02909
331111006438	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
331111006439	Ligand Binding Site [chemical binding]; other site
331111006440	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
331111006441	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
331111006442	active site
331111006443	homotetramer interface [polypeptide binding]; other site
331111006444	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
331111006445	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
331111006446	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
331111006447	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
331111006448	TM-ABC transporter signature motif; other site
331111006449	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
331111006450	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
331111006451	Walker A/P-loop; other site
331111006452	ATP binding site [chemical binding]; other site
331111006453	Q-loop/lid; other site
331111006454	ABC transporter signature motif; other site
331111006455	Walker B; other site
331111006456	D-loop; other site
331111006457	H-loop/switch region; other site
331111006458	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
331111006459	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
331111006460	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
331111006461	ligand binding site [chemical binding]; other site
331111006462	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
331111006463	Ferritin-like domain; Region: Ferritin; pfam00210
331111006464	ferroxidase diiron center [ion binding]; other site
331111006465	YecR-like lipoprotein; Region: YecR; pfam13992
331111006466	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
331111006467	Ferritin-like domain; Region: Ferritin; pfam00210
331111006468	ferroxidase diiron center [ion binding]; other site
331111006469	probable metal-binding protein; Region: matur_matur; TIGR03853
331111006470	tyrosine transporter TyrP; Provisional; Region: PRK15132
331111006471	aromatic amino acid transport protein; Region: araaP; TIGR00837
331111006472	hypothetical protein; Provisional; Region: PRK10396
331111006473	yecA family protein; Region: ygfB_yecA; TIGR02292
331111006474	SEC-C motif; Region: SEC-C; pfam02810
331111006475	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
331111006476	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
331111006477	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
331111006478	GIY-YIG motif/motif A; other site
331111006479	active site
331111006480	catalytic site [active]
331111006481	putative DNA binding site [nucleotide binding]; other site
331111006482	metal binding site [ion binding]; metal-binding site
331111006483	UvrB/uvrC motif; Region: UVR; pfam02151
331111006484	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
331111006485	Helix-hairpin-helix motif; Region: HHH; pfam00633
331111006486	response regulator; Provisional; Region: PRK09483
331111006487	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111006488	active site
331111006489	phosphorylation site [posttranslational modification]
331111006490	intermolecular recognition site; other site
331111006491	dimerization interface [polypeptide binding]; other site
331111006492	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111006493	DNA binding residues [nucleotide binding]
331111006494	dimerization interface [polypeptide binding]; other site
331111006495	hypothetical protein; Provisional; Region: PRK10613
331111006496	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
331111006497	Autoinducer binding domain; Region: Autoind_bind; pfam03472
331111006498	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111006499	DNA binding residues [nucleotide binding]
331111006500	dimerization interface [polypeptide binding]; other site
331111006501	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
331111006502	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
331111006503	Walker A/P-loop; other site
331111006504	ATP binding site [chemical binding]; other site
331111006505	Q-loop/lid; other site
331111006506	ABC transporter signature motif; other site
331111006507	Walker B; other site
331111006508	D-loop; other site
331111006509	H-loop/switch region; other site
331111006510	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
331111006511	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111006512	dimer interface [polypeptide binding]; other site
331111006513	conserved gate region; other site
331111006514	putative PBP binding loops; other site
331111006515	ABC-ATPase subunit interface; other site
331111006516	D-cysteine desulfhydrase; Validated; Region: PRK03910
331111006517	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
331111006518	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111006519	catalytic residue [active]
331111006520	cystine transporter subunit; Provisional; Region: PRK11260
331111006521	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111006522	substrate binding pocket [chemical binding]; other site
331111006523	membrane-bound complex binding site; other site
331111006524	hinge residues; other site
331111006525	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
331111006526	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
331111006527	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
331111006528	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
331111006529	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
331111006530	DNA binding residues [nucleotide binding]
331111006531	flagellin; Validated; Region: PRK08026
331111006532	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
331111006533	Flagellin protein; Region: FliC; pfam12445
331111006534	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
331111006535	flagellar capping protein; Reviewed; Region: fliD; PRK08032
331111006536	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
331111006537	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
331111006538	Flagellar protein FliS; Region: FliS; cl00654
331111006539	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
331111006540	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
331111006541	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
331111006542	active site
331111006543	Na/Ca binding site [ion binding]; other site
331111006544	catalytic site [active]
331111006545	lipoprotein; Provisional; Region: PRK10397
331111006546	putative inner membrane protein; Provisional; Region: PRK11099
331111006547	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
331111006548	CPxP  motif; other site
331111006549	hypothetical protein; Provisional; Region: PRK09951
331111006550	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
331111006551	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
331111006552	Probable transposase; Region: OrfB_IS605; pfam01385
331111006553	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
331111006554	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
331111006555	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
331111006556	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
331111006557	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
331111006558	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
331111006559	flagellar motor switch protein FliG; Region: fliG; TIGR00207
331111006560	FliG C-terminal domain; Region: FliG_C; pfam01706
331111006561	flagellar assembly protein H; Validated; Region: fliH; PRK05687
331111006562	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
331111006563	Flagellar assembly protein FliH; Region: FliH; pfam02108
331111006564	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
331111006565	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
331111006566	Walker A motif/ATP binding site; other site
331111006567	Walker B motif; other site
331111006568	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
331111006569	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
331111006570	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
331111006571	flagellar hook-length control protein; Provisional; Region: PRK10118
331111006572	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
331111006573	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
331111006574	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
331111006575	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
331111006576	flagellar motor switch protein; Validated; Region: fliN; PRK05698
331111006577	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
331111006578	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
331111006579	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
331111006580	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
331111006581	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
331111006582	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111006583	DNA binding residues [nucleotide binding]
331111006584	dimerization interface [polypeptide binding]; other site
331111006585	hypothetical protein; Provisional; Region: PRK10708
331111006586	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
331111006587	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
331111006588	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111006589	active site
331111006590	motif I; other site
331111006591	motif II; other site
331111006592	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
331111006593	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111006594	metal binding site [ion binding]; metal-binding site
331111006595	active site
331111006596	I-site; other site
331111006597	Uncharacterized small protein [Function unknown]; Region: COG5475
331111006598	hypothetical protein; Provisional; Region: PRK10062
331111006599	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
331111006600	EamA-like transporter family; Region: EamA; pfam00892
331111006601	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
331111006602	additional DNA contacts [nucleotide binding]; other site
331111006603	mismatch recognition site; other site
331111006604	active site
331111006605	zinc binding site [ion binding]; other site
331111006606	DNA intercalation site [nucleotide binding]; other site
331111006607	DNA cytosine methylase; Provisional; Region: PRK10458
331111006608	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
331111006609	cofactor binding site; other site
331111006610	DNA binding site [nucleotide binding]
331111006611	substrate interaction site [chemical binding]; other site
331111006612	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
331111006613	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
331111006614	Zn2+ binding site [ion binding]; other site
331111006615	Mg2+ binding site [ion binding]; other site
331111006616	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
331111006617	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
331111006618	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
331111006619	eyelet of channel; other site
331111006620	trimer interface [polypeptide binding]; other site
331111006621	chaperone protein HchA; Provisional; Region: PRK04155
331111006622	Type 1 glutamine amidotransferase (GATase1)-like domain found in Escherichia coli Hsp31 protein (EcHsp31); Region: GATase1_EcHsp31_like; cd03148
331111006623	dimer interface [polypeptide binding]; other site
331111006624	metal binding site [ion binding]; metal-binding site
331111006625	potential oxyanion hole; other site
331111006626	potential catalytic triad [active]
331111006627	conserved cys residue [active]
331111006628	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
331111006629	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111006630	dimer interface [polypeptide binding]; other site
331111006631	phosphorylation site [posttranslational modification]
331111006632	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111006633	ATP binding site [chemical binding]; other site
331111006634	Mg2+ binding site [ion binding]; other site
331111006635	G-X-G motif; other site
331111006636	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
331111006637	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111006638	active site
331111006639	phosphorylation site [posttranslational modification]
331111006640	intermolecular recognition site; other site
331111006641	dimerization interface [polypeptide binding]; other site
331111006642	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
331111006643	DNA binding site [nucleotide binding]
331111006644	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
331111006645	active site
331111006646	homotetramer interface [polypeptide binding]; other site
331111006647	TMAO/DMSO reductase; Reviewed; Region: PRK05363
331111006648	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
331111006649	Moco binding site; other site
331111006650	metal coordination site [ion binding]; other site
331111006651	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
331111006652	zinc/cadmium-binding protein; Provisional; Region: PRK10306
331111006653	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
331111006654	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
331111006655	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
331111006656	Phage tail tube protein FII; Region: Phage_tube; cl01390
331111006657	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
331111006658	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
331111006659	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
331111006660	Phage tail protein (Tail_P2_I); Region: Tail_P2_I; pfam09684
331111006661	Baseplate J-like protein; Region: Baseplate_J; cl01294
331111006662	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
331111006663	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
331111006664	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
331111006665	DNA packaging protein FI; Region: Packaging_FI; pfam14000
331111006666	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
331111006667	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
331111006668	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
331111006669	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
331111006670	tandem repeat interface [polypeptide binding]; other site
331111006671	oligomer interface [polypeptide binding]; other site
331111006672	active site residues [active]
331111006673	transposase/IS protein; Provisional; Region: PRK09183
331111006674	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111006675	Walker A motif; other site
331111006676	ATP binding site [chemical binding]; other site
331111006677	Walker B motif; other site
331111006678	arginine finger; other site
331111006679	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
331111006680	Helix-turn-helix domain; Region: HTH_38; pfam13936
331111006681	Integrase core domain; Region: rve; pfam00665
331111006682	Integrase core domain; Region: rve_3; cl15866
331111006683	Phage terminase large subunit (GpA); Region: Terminase_GpA; pfam05876
331111006684	TIGR02594 family protein; Region: TIGR02594
331111006685	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
331111006686	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
331111006687	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
331111006688	GIY-YIG domain of uncharacterized proteins from bacteria and their eukaryotic homologs; Region: GIY-YIG_COG3680; cd10440
331111006689	GIY-YIG motif/motif A; other site
331111006690	putative active site [active]
331111006691	putative metal binding site [ion binding]; other site
331111006692	HNH endonuclease; Region: HNH_2; pfam13391
331111006693	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
331111006694	ORF6N domain; Region: ORF6N; pfam10543
331111006695	replicative DNA helicase; Region: DnaB; TIGR00665
331111006696	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
331111006697	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
331111006698	Walker A motif; other site
331111006699	ATP binding site [chemical binding]; other site
331111006700	Walker B motif; other site
331111006701	DNA binding loops [nucleotide binding]
331111006702	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
331111006703	transcriptional repressor DicA; Reviewed; Region: PRK09706
331111006704	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111006705	non-specific DNA binding site [nucleotide binding]; other site
331111006706	salt bridge; other site
331111006707	sequence-specific DNA binding site [nucleotide binding]; other site
331111006708	exonuclease VIII; Reviewed; Region: PRK09709
331111006709	Siphovirus Gp157; Region: Sipho_Gp157; pfam05565
331111006710	Domain of unknown function (DUF4224); Region: DUF4224; pfam13986
331111006711	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
331111006712	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
331111006713	active site
331111006714	DNA binding site [nucleotide binding]
331111006715	Int/Topo IB signature motif; other site
331111006716	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
331111006717	putative invasin; Provisional; Region: PRK10177
331111006718	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
331111006719	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
331111006720	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
331111006721	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
331111006722	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
331111006723	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
331111006724	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
331111006725	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
331111006726	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
331111006727	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
331111006728	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
331111006729	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
331111006730	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
331111006731	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
331111006732	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
331111006733	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
331111006734	shikimate transporter; Provisional; Region: PRK09952
331111006735	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111006736	putative substrate translocation pore; other site
331111006737	AMP nucleosidase; Provisional; Region: PRK08292
331111006738	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
331111006739	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
331111006740	hypothetical protein; Provisional; Region: PRK12378
331111006741	MATE family multidrug exporter; Provisional; Region: PRK10189
331111006742	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
331111006743	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
331111006744	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111006745	The C-terminal substrate binding domain of LysR-type transcriptional regulator Cbl, which is required for expression of sulfate starvation-inducible (ssi) genes, contains the type 2 periplasmic binding fold; Region: PBP2_Cbl; cd08444
331111006746	putative substrate binding site [chemical binding]; other site
331111006747	dimerization interface [polypeptide binding]; other site
331111006748	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
331111006749	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111006750	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
331111006751	putative dimerization interface [polypeptide binding]; other site
331111006752	L,D-transpeptidase; Provisional; Region: PRK10190
331111006753	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
331111006754	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
331111006755	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
331111006756	putative dimer interface [polypeptide binding]; other site
331111006757	active site pocket [active]
331111006758	putative cataytic base [active]
331111006759	cobalamin 5'-phosphate synthase/cobalamin synthase; Region: cobS; TIGR00317
331111006760	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
331111006761	homotrimer interface [polypeptide binding]; other site
331111006762	Walker A motif; other site
331111006763	GTP binding site [chemical binding]; other site
331111006764	Walker B motif; other site
331111006765	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
331111006766	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
331111006767	Sensory domain found in PocR; Region: PocR; pfam10114
331111006768	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
331111006769	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111006770	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111006771	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
331111006772	amphipathic channel; other site
331111006773	Asn-Pro-Ala signature motifs; other site
331111006774	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
331111006775	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
331111006776	Hexamer interface [polypeptide binding]; other site
331111006777	Putative hexagonal pore residue; other site
331111006778	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutL; COG4816
331111006779	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
331111006780	putative hexamer interface [polypeptide binding]; other site
331111006781	putative hexagonal pore; other site
331111006782	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
331111006783	putative hexamer interface [polypeptide binding]; other site
331111006784	putative hexagonal pore; other site
331111006785	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
331111006786	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
331111006787	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
331111006788	alpha-beta subunit interface [polypeptide binding]; other site
331111006789	alpha-gamma subunit interface [polypeptide binding]; other site
331111006790	active site
331111006791	substrate and K+ binding site; other site
331111006792	K+ binding site [ion binding]; other site
331111006793	cobalamin binding site [chemical binding]; other site
331111006794	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
331111006795	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
331111006796	Cell division protein FtsA; Region: FtsA; cl17206
331111006797	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
331111006798	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
331111006799	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
331111006800	Hexamer interface [polypeptide binding]; other site
331111006801	Putative hexagonal pore residue; other site
331111006802	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
331111006803	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
331111006804	putative hexamer interface [polypeptide binding]; other site
331111006805	putative hexagonal pore; other site
331111006806	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
331111006807	Propanediol utilisation protein PduL; Region: PduL; pfam06130
331111006808	Propanediol utilisation protein PduL; Region: PduL; pfam06130
331111006809	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
331111006810	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
331111006811	Hexamer/Pentamer interface [polypeptide binding]; other site
331111006812	central pore; other site
331111006813	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
331111006814	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
331111006815	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
331111006816	putative catalytic cysteine [active]
331111006817	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
331111006818	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
331111006819	putative active site [active]
331111006820	metal binding site [ion binding]; metal-binding site
331111006821	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
331111006822	SLBB domain; Region: SLBB; pfam10531
331111006823	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
331111006824	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
331111006825	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
331111006826	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
331111006827	putative hexamer interface [polypeptide binding]; other site
331111006828	putative hexagonal pore; other site
331111006829	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
331111006830	putative hexamer interface [polypeptide binding]; other site
331111006831	putative hexagonal pore; other site
331111006832	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
331111006833	putative hexamer interface [polypeptide binding]; other site
331111006834	putative hexagonal pore; other site
331111006835	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
331111006836	G1 box; other site
331111006837	GTP/Mg2+ binding site [chemical binding]; other site
331111006838	G2 box; other site
331111006839	G3 box; other site
331111006840	Switch II region; other site
331111006841	G4 box; other site
331111006842	G5 box; other site
331111006843	hypothetical protein; Provisional; Region: PRK05423
331111006844	Predicted membrane protein [Function unknown]; Region: COG1289
331111006845	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
331111006846	DNA gyrase inhibitor; Provisional; Region: PRK10016
331111006847	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
331111006848	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
331111006849	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
331111006850	exonuclease I; Provisional; Region: sbcB; PRK11779
331111006851	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
331111006852	active site
331111006853	catalytic site [active]
331111006854	substrate binding site [chemical binding]; other site
331111006855	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
331111006856	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
331111006857	CPxP  motif; other site
331111006858	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
331111006859	Sulphur transport; Region: Sulf_transp; pfam04143
331111006860	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
331111006861	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111006862	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
331111006863	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
331111006864	dimerization interface [polypeptide binding]; other site
331111006865	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
331111006866	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
331111006867	putative NAD(P) binding site [chemical binding]; other site
331111006868	Plasmid encoded toxin Txe; Region: Plasmid_Txe; pfam06769
331111006869	antitoxin YefM; Provisional; Region: PRK11409
331111006870	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
331111006871	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
331111006872	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
331111006873	Histidinol dehydrogenase; Region: Histidinol_dh; pfam00815
331111006874	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
331111006875	NAD binding site [chemical binding]; other site
331111006876	dimerization interface [polypeptide binding]; other site
331111006877	product binding site; other site
331111006878	substrate binding site [chemical binding]; other site
331111006879	zinc binding site [ion binding]; other site
331111006880	catalytic residues [active]
331111006881	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
331111006882	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
331111006883	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111006884	homodimer interface [polypeptide binding]; other site
331111006885	catalytic residue [active]
331111006886	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
331111006887	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111006888	active site
331111006889	motif I; other site
331111006890	motif II; other site
331111006891	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
331111006892	putative active site pocket [active]
331111006893	4-fold oligomerization interface [polypeptide binding]; other site
331111006894	metal binding residues [ion binding]; metal-binding site
331111006895	3-fold/trimer interface [polypeptide binding]; other site
331111006896	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
331111006897	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
331111006898	putative active site [active]
331111006899	oxyanion strand; other site
331111006900	catalytic triad [active]
331111006901	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
331111006902	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
331111006903	catalytic residues [active]
331111006904	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
331111006905	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
331111006906	substrate binding site [chemical binding]; other site
331111006907	glutamase interaction surface [polypeptide binding]; other site
331111006908	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
331111006909	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
331111006910	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
331111006911	metal binding site [ion binding]; metal-binding site
331111006912	chain length determinant protein WzzB; Provisional; Region: PRK15471
331111006913	Chain length determinant protein; Region: Wzz; pfam02706
331111006914	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
331111006915	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
331111006916	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
331111006917	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
331111006918	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
331111006919	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
331111006920	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
331111006921	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
331111006922	Vi polysaccharide biosynthesis protein TviC; Provisional; Region: PRK15181
331111006923	UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs; Region: UDP_AE_SDR_e; cd05256
331111006924	NAD binding site [chemical binding]; other site
331111006925	substrate binding site [chemical binding]; other site
331111006926	homodimer interface [polypeptide binding]; other site
331111006927	active site
331111006928	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
331111006929	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
331111006930	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
331111006931	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
331111006932	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
331111006933	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
331111006934	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
331111006935	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
331111006936	Probable Catalytic site; other site
331111006937	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
331111006938	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
331111006939	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
331111006940	substrate binding site; other site
331111006941	tetramer interface; other site
331111006942	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
331111006943	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
331111006944	NADP binding site [chemical binding]; other site
331111006945	active site
331111006946	putative substrate binding site [chemical binding]; other site
331111006947	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
331111006948	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
331111006949	NAD binding site [chemical binding]; other site
331111006950	substrate binding site [chemical binding]; other site
331111006951	homodimer interface [polypeptide binding]; other site
331111006952	active site
331111006953	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
331111006954	active site
331111006955	tetramer interface; other site
331111006956	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
331111006957	colanic acid biosynthesis glycosyltransferase WcaL; Region: wcaL; TIGR04005
331111006958	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
331111006959	putative ADP-binding pocket [chemical binding]; other site
331111006960	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
331111006961	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
331111006962	colanic acid exporter; Provisional; Region: PRK10459
331111006963	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
331111006964	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
331111006965	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
331111006966	phosphomannomutase CpsG; Provisional; Region: PRK15414
331111006967	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
331111006968	active site
331111006969	substrate binding site [chemical binding]; other site
331111006970	metal binding site [ion binding]; metal-binding site
331111006971	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
331111006972	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
331111006973	Substrate binding site; other site
331111006974	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
331111006975	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
331111006976	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
331111006977	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
331111006978	active site
331111006979	GDP-Mannose binding site [chemical binding]; other site
331111006980	dimer interface [polypeptide binding]; other site
331111006981	modified nudix motif
331111006982	metal binding site [ion binding]; metal-binding site
331111006983	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
331111006984	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
331111006985	NADP binding site [chemical binding]; other site
331111006986	active site
331111006987	putative substrate binding site [chemical binding]; other site
331111006988	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
331111006989	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
331111006990	NADP-binding site; other site
331111006991	homotetramer interface [polypeptide binding]; other site
331111006992	substrate binding site [chemical binding]; other site
331111006993	homodimer interface [polypeptide binding]; other site
331111006994	active site
331111006995	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
331111006996	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
331111006997	putative trimer interface [polypeptide binding]; other site
331111006998	putative active site [active]
331111006999	putative substrate binding site [chemical binding]; other site
331111007000	putative CoA binding site [chemical binding]; other site
331111007001	putative glycosyl transferase; Provisional; Region: PRK10063
331111007002	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
331111007003	metal-binding site
331111007004	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
331111007005	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
331111007006	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
331111007007	putative acyl transferase; Provisional; Region: PRK10191
331111007008	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
331111007009	trimer interface [polypeptide binding]; other site
331111007010	active site
331111007011	substrate binding site [chemical binding]; other site
331111007012	CoA binding site [chemical binding]; other site
331111007013	putative glycosyl transferase; Provisional; Region: PRK10018
331111007014	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
331111007015	active site
331111007016	tyrosine kinase; Provisional; Region: PRK11519
331111007017	Chain length determinant protein; Region: Wzz; pfam02706
331111007018	Chain length determinant protein; Region: Wzz; cl15801
331111007019	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
331111007020	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
331111007021	Low molecular weight phosphatase family; Region: LMWPc; cd00115
331111007022	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
331111007023	active site
331111007024	polysaccharide export protein Wza; Provisional; Region: PRK15078
331111007025	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
331111007026	SLBB domain; Region: SLBB; pfam10531
331111007027	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
331111007028	FOG: CBS domain [General function prediction only]; Region: COG0517
331111007029	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
331111007030	Transporter associated domain; Region: CorC_HlyC; smart01091
331111007031	putative assembly protein; Provisional; Region: PRK10833
331111007032	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
331111007033	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
331111007034	trimer interface [polypeptide binding]; other site
331111007035	active site
331111007036	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
331111007037	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
331111007038	ATP-binding site [chemical binding]; other site
331111007039	Sugar specificity; other site
331111007040	Pyrimidine base specificity; other site
331111007041	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
331111007042	putative diguanylate cyclase; Provisional; Region: PRK09776
331111007043	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
331111007044	putative active site [active]
331111007045	heme pocket [chemical binding]; other site
331111007046	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
331111007047	putative active site [active]
331111007048	heme pocket [chemical binding]; other site
331111007049	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
331111007050	putative active site [active]
331111007051	heme pocket [chemical binding]; other site
331111007052	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111007053	metal binding site [ion binding]; metal-binding site
331111007054	active site
331111007055	I-site; other site
331111007056	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
331111007057	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
331111007058	AlkA N-terminal domain; Region: AlkA_N; smart01009
331111007059	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
331111007060	minor groove reading motif; other site
331111007061	helix-hairpin-helix signature motif; other site
331111007062	substrate binding pocket [chemical binding]; other site
331111007063	active site
331111007064	putative chaperone; Provisional; Region: PRK11678
331111007065	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
331111007066	nucleotide binding site [chemical binding]; other site
331111007067	putative NEF/HSP70 interaction site [polypeptide binding]; other site
331111007068	SBD interface [polypeptide binding]; other site
331111007069	Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only]; Region: COG4248
331111007070	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
331111007071	substrate binding site [chemical binding]; other site
331111007072	activation loop (A-loop); other site
331111007073	Y-family of DNA polymerases; Region: PolY; cl12025
331111007074	Protein phosphatase 2C; Region: PP2C_2; pfam13672
331111007075	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
331111007076	metal ion-dependent adhesion site (MIDAS); other site
331111007077	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
331111007078	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
331111007079	HlyD family secretion protein; Region: HlyD_3; pfam13437
331111007080	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
331111007081	Protein export membrane protein; Region: SecD_SecF; cl14618
331111007082	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
331111007083	putative transporter; Provisional; Region: PRK10504
331111007084	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111007085	putative substrate translocation pore; other site
331111007086	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
331111007087	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
331111007088	dimerization interface [polypeptide binding]; other site
331111007089	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111007090	dimer interface [polypeptide binding]; other site
331111007091	phosphorylation site [posttranslational modification]
331111007092	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111007093	ATP binding site [chemical binding]; other site
331111007094	Mg2+ binding site [ion binding]; other site
331111007095	G-X-G motif; other site
331111007096	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
331111007097	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111007098	active site
331111007099	phosphorylation site [posttranslational modification]
331111007100	intermolecular recognition site; other site
331111007101	dimerization interface [polypeptide binding]; other site
331111007102	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
331111007103	DNA binding site [nucleotide binding]
331111007104	Uncharacterized conserved protein [Function unknown]; Region: COG3422
331111007105	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
331111007106	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
331111007107	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
331111007108	putative protease; Provisional; Region: PRK15452
331111007109	Peptidase family U32; Region: Peptidase_U32; pfam01136
331111007110	lipid kinase; Reviewed; Region: PRK13054
331111007111	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
331111007112	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
331111007113	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
331111007114	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
331111007115	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
331111007116	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
331111007117	putative NAD(P) binding site [chemical binding]; other site
331111007118	catalytic Zn binding site [ion binding]; other site
331111007119	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
331111007120	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
331111007121	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
331111007122	active site
331111007123	P-loop; other site
331111007124	phosphorylation site [posttranslational modification]
331111007125	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
331111007126	active site
331111007127	phosphorylation site [posttranslational modification]
331111007128	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
331111007129	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
331111007130	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
331111007131	intersubunit interface [polypeptide binding]; other site
331111007132	active site
331111007133	zinc binding site [ion binding]; other site
331111007134	Na+ binding site [ion binding]; other site
331111007135	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
331111007136	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
331111007137	putative active site; other site
331111007138	catalytic residue [active]
331111007139	nucleoside transporter; Region: 2A0110; TIGR00889
331111007140	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111007141	putative substrate translocation pore; other site
331111007142	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
331111007143	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
331111007144	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
331111007145	substrate binding site [chemical binding]; other site
331111007146	ATP binding site [chemical binding]; other site
331111007147	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
331111007148	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111007149	DNA-binding site [nucleotide binding]; DNA binding site
331111007150	UTRA domain; Region: UTRA; pfam07702
331111007151	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
331111007152	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
331111007153	active site
331111007154	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
331111007155	dimer interface [polypeptide binding]; other site
331111007156	substrate binding site [chemical binding]; other site
331111007157	ATP binding site [chemical binding]; other site
331111007158	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
331111007159	substrate binding site [chemical binding]; other site
331111007160	multimerization interface [polypeptide binding]; other site
331111007161	ATP binding site [chemical binding]; other site
331111007162	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
331111007163	putative metal binding site [ion binding]; other site
331111007164	putative homodimer interface [polypeptide binding]; other site
331111007165	putative homotetramer interface [polypeptide binding]; other site
331111007166	putative homodimer-homodimer interface [polypeptide binding]; other site
331111007167	putative allosteric switch controlling residues; other site
331111007168	Predicted integral membrane protein [Function unknown]; Region: COG5455
331111007169	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
331111007170	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
331111007171	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
331111007172	PapC N-terminal domain; Region: PapC_N; pfam13954
331111007173	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
331111007174	PapC C-terminal domain; Region: PapC_C; pfam13953
331111007175	putative fimbrial assembly chaperone protein StcB; Provisional; Region: PRK15253
331111007176	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
331111007177	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
331111007178	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
331111007179	antiporter inner membrane protein; Provisional; Region: PRK11670
331111007180	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
331111007181	Walker A motif; other site
331111007182	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
331111007183	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
331111007184	active site
331111007185	HIGH motif; other site
331111007186	KMSKS motif; other site
331111007187	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
331111007188	tRNA binding surface [nucleotide binding]; other site
331111007189	anticodon binding site; other site
331111007190	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
331111007191	dimer interface [polypeptide binding]; other site
331111007192	putative tRNA-binding site [nucleotide binding]; other site
331111007193	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
331111007194	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
331111007195	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
331111007196	MoxR-like ATPases [General function prediction only]; Region: COG0714
331111007197	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111007198	Walker A motif; other site
331111007199	ATP binding site [chemical binding]; other site
331111007200	Walker B motif; other site
331111007201	arginine finger; other site
331111007202	VWA domain containing CoxE-like protein; Region: VWA_CoxE; pfam05762
331111007203	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
331111007204	metal ion-dependent adhesion site (MIDAS); other site
331111007205	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
331111007206	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
331111007207	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
331111007208	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
331111007209	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
331111007210	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111007211	active site
331111007212	phosphorylation site [posttranslational modification]
331111007213	intermolecular recognition site; other site
331111007214	dimerization interface [polypeptide binding]; other site
331111007215	LytTr DNA-binding domain; Region: LytTR; pfam04397
331111007216	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
331111007217	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
331111007218	GAF domain; Region: GAF; pfam01590
331111007219	Histidine kinase; Region: His_kinase; pfam06580
331111007220	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111007221	ATP binding site [chemical binding]; other site
331111007222	Mg2+ binding site [ion binding]; other site
331111007223	G-X-G motif; other site
331111007224	transcriptional regulator MirA; Provisional; Region: PRK15043
331111007225	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
331111007226	DNA binding residues [nucleotide binding]
331111007227	hypothetical protein; Provisional; Region: PRK13681
331111007228	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
331111007229	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111007230	dimer interface [polypeptide binding]; other site
331111007231	conserved gate region; other site
331111007232	putative PBP binding loops; other site
331111007233	ABC-ATPase subunit interface; other site
331111007234	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
331111007235	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
331111007236	Walker A/P-loop; other site
331111007237	ATP binding site [chemical binding]; other site
331111007238	Q-loop/lid; other site
331111007239	ABC transporter signature motif; other site
331111007240	Walker B; other site
331111007241	D-loop; other site
331111007242	H-loop/switch region; other site
331111007243	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
331111007244	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111007245	dimer interface [polypeptide binding]; other site
331111007246	conserved gate region; other site
331111007247	ABC-ATPase subunit interface; other site
331111007248	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
331111007249	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
331111007250	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
331111007251	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
331111007252	D-lactate dehydrogenase; Provisional; Region: PRK11183
331111007253	FAD binding domain; Region: FAD_binding_4; pfam01565
331111007254	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
331111007255	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
331111007256	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
331111007257	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
331111007258	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
331111007259	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
331111007260	oxidoreductase; Provisional; Region: PRK12743
331111007261	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
331111007262	NAD(P) binding site [chemical binding]; other site
331111007263	active site
331111007264	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
331111007265	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
331111007266	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
331111007267	FMN binding site [chemical binding]; other site
331111007268	active site
331111007269	catalytic residues [active]
331111007270	substrate binding site [chemical binding]; other site
331111007271	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
331111007272	maleylacetoacetate isomerase; Region: maiA; TIGR01262
331111007273	C-terminal domain interface [polypeptide binding]; other site
331111007274	GSH binding site (G-site) [chemical binding]; other site
331111007275	putative dimer interface [polypeptide binding]; other site
331111007276	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
331111007277	dimer interface [polypeptide binding]; other site
331111007278	N-terminal domain interface [polypeptide binding]; other site
331111007279	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
331111007280	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
331111007281	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
331111007282	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
331111007283	Cupin domain; Region: Cupin_2; pfam07883
331111007284	Cupin domain; Region: Cupin_2; cl17218
331111007285	benzoate transport; Region: 2A0115; TIGR00895
331111007286	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111007287	putative substrate translocation pore; other site
331111007288	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
331111007289	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111007290	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
331111007291	dimerization interface [polypeptide binding]; other site
331111007292	hypothetical protein; Provisional; Region: PRK01821
331111007293	hypothetical protein; Provisional; Region: PRK10711
331111007294	cytidine deaminase; Provisional; Region: PRK09027
331111007295	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
331111007296	active site
331111007297	catalytic motif [active]
331111007298	Zn binding site [ion binding]; other site
331111007299	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
331111007300	active site
331111007301	catalytic motif [active]
331111007302	Zn binding site [ion binding]; other site
331111007303	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
331111007304	putative active site [active]
331111007305	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
331111007306	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
331111007307	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
331111007308	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111007309	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
331111007310	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
331111007311	homodimer interface [polypeptide binding]; other site
331111007312	active site
331111007313	FMN binding site [chemical binding]; other site
331111007314	substrate binding site [chemical binding]; other site
331111007315	4Fe-4S binding domain; Region: Fer4; pfam00037
331111007316	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
331111007317	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
331111007318	TM-ABC transporter signature motif; other site
331111007319	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
331111007320	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
331111007321	Walker A/P-loop; other site
331111007322	ATP binding site [chemical binding]; other site
331111007323	Q-loop/lid; other site
331111007324	ABC transporter signature motif; other site
331111007325	Walker B; other site
331111007326	D-loop; other site
331111007327	H-loop/switch region; other site
331111007328	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
331111007329	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
331111007330	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
331111007331	ligand binding site [chemical binding]; other site
331111007332	calcium binding site [ion binding]; other site
331111007333	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
331111007334	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
331111007335	DNA binding site [nucleotide binding]
331111007336	domain linker motif; other site
331111007337	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
331111007338	dimerization interface (closed form) [polypeptide binding]; other site
331111007339	ligand binding site [chemical binding]; other site
331111007340	Predicted membrane protein [Function unknown]; Region: COG2311
331111007341	hypothetical protein; Provisional; Region: PRK10835
331111007342	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
331111007343	homodecamer interface [polypeptide binding]; other site
331111007344	GTP cyclohydrolase I; Provisional; Region: PLN03044
331111007345	active site
331111007346	putative catalytic site residues [active]
331111007347	zinc binding site [ion binding]; other site
331111007348	GTP-CH-I/GFRP interaction surface; other site
331111007349	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
331111007350	S-formylglutathione hydrolase; Region: PLN02442
331111007351	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
331111007352	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
331111007353	N-terminal plug; other site
331111007354	ligand-binding site [chemical binding]; other site
331111007355	lysine transporter; Provisional; Region: PRK10836
331111007356	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
331111007357	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111007358	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
331111007359	putative dimerization interface [polypeptide binding]; other site
331111007360	conserved hypothetical integral membrane protein; Region: TIGR00698
331111007361	endonuclease IV; Provisional; Region: PRK01060
331111007362	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
331111007363	AP (apurinic/apyrimidinic) site pocket; other site
331111007364	DNA interaction; other site
331111007365	Metal-binding active site; metal-binding site
331111007366	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
331111007367	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
331111007368	Nucleoside recognition; Region: Gate; pfam07670
331111007369	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
331111007370	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
331111007371	active site
331111007372	tetramer interface [polypeptide binding]; other site
331111007373	DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402
331111007374	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
331111007375	ligand binding site [chemical binding]; other site
331111007376	flexible hinge region; other site
331111007377	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
331111007378	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
331111007379	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
331111007380	Nucleoside recognition; Region: Gate; pfam07670
331111007381	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
331111007382	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
331111007383	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
331111007384	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
331111007385	substrate binding site [chemical binding]; other site
331111007386	ATP binding site [chemical binding]; other site
331111007387	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
331111007388	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
331111007389	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
331111007390	active site
331111007391	P-loop; other site
331111007392	phosphorylation site [posttranslational modification]
331111007393	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
331111007394	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
331111007395	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
331111007396	putative substrate binding site [chemical binding]; other site
331111007397	putative ATP binding site [chemical binding]; other site
331111007398	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
331111007399	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
331111007400	active site
331111007401	phosphorylation site [posttranslational modification]
331111007402	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
331111007403	dimerization domain swap beta strand [polypeptide binding]; other site
331111007404	regulatory protein interface [polypeptide binding]; other site
331111007405	active site
331111007406	regulatory phosphorylation site [posttranslational modification]; other site
331111007407	sugar efflux transporter B; Provisional; Region: PRK15011
331111007408	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111007409	putative substrate translocation pore; other site
331111007410	elongation factor P; Provisional; Region: PRK04542
331111007411	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
331111007412	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
331111007413	RNA binding site [nucleotide binding]; other site
331111007414	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
331111007415	RNA binding site [nucleotide binding]; other site
331111007416	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
331111007417	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
331111007418	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
331111007419	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
331111007420	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
331111007421	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
331111007422	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
331111007423	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
331111007424	active site
331111007425	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
331111007426	NlpC/P60 family; Region: NLPC_P60; pfam00877
331111007427	phage resistance protein; Provisional; Region: PRK10551
331111007428	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
331111007429	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
331111007430	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
331111007431	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
331111007432	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
331111007433	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111007434	dimer interface [polypeptide binding]; other site
331111007435	conserved gate region; other site
331111007436	putative PBP binding loops; other site
331111007437	ABC-ATPase subunit interface; other site
331111007438	microcin C ABC transporter permease; Provisional; Region: PRK15021
331111007439	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111007440	dimer interface [polypeptide binding]; other site
331111007441	conserved gate region; other site
331111007442	ABC-ATPase subunit interface; other site
331111007443	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
331111007444	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
331111007445	Walker A/P-loop; other site
331111007446	ATP binding site [chemical binding]; other site
331111007447	Q-loop/lid; other site
331111007448	ABC transporter signature motif; other site
331111007449	Walker B; other site
331111007450	D-loop; other site
331111007451	H-loop/switch region; other site
331111007452	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
331111007453	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
331111007454	Walker A/P-loop; other site
331111007455	ATP binding site [chemical binding]; other site
331111007456	Q-loop/lid; other site
331111007457	ABC transporter signature motif; other site
331111007458	Walker B; other site
331111007459	D-loop; other site
331111007460	H-loop/switch region; other site
331111007461	hypothetical protein; Provisional; Region: PRK11835
331111007462	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111007463	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
331111007464	putative substrate translocation pore; other site
331111007465	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
331111007466	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
331111007467	RNA binding surface [nucleotide binding]; other site
331111007468	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
331111007469	active site
331111007470	uracil binding [chemical binding]; other site
331111007471	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
331111007472	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
331111007473	ATP binding site [chemical binding]; other site
331111007474	putative Mg++ binding site [ion binding]; other site
331111007475	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111007476	nucleotide binding region [chemical binding]; other site
331111007477	ATP-binding site [chemical binding]; other site
331111007478	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
331111007479	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
331111007480	5S rRNA interface [nucleotide binding]; other site
331111007481	CTC domain interface [polypeptide binding]; other site
331111007482	L16 interface [polypeptide binding]; other site
331111007483	Nucleoid-associated protein [General function prediction only]; Region: COG3081
331111007484	nucleoid-associated protein NdpA; Validated; Region: PRK00378
331111007485	hypothetical protein; Provisional; Region: PRK13689
331111007486	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
331111007487	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
331111007488	Sulfatase; Region: Sulfatase; pfam00884
331111007489	transcriptional regulator NarP; Provisional; Region: PRK10403
331111007490	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111007491	active site
331111007492	phosphorylation site [posttranslational modification]
331111007493	intermolecular recognition site; other site
331111007494	dimerization interface [polypeptide binding]; other site
331111007495	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111007496	DNA binding residues [nucleotide binding]
331111007497	dimerization interface [polypeptide binding]; other site
331111007498	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
331111007499	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
331111007500	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
331111007501	binding surface
331111007502	TPR motif; other site
331111007503	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
331111007504	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
331111007505	catalytic residues [active]
331111007506	central insert; other site
331111007507	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
331111007508	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
331111007509	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
331111007510	heme exporter protein CcmC; Region: ccmC; TIGR01191
331111007511	heme exporter protein CcmB; Region: ccmB; TIGR01190
331111007512	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
331111007513	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
331111007514	Walker A/P-loop; other site
331111007515	ATP binding site [chemical binding]; other site
331111007516	Q-loop/lid; other site
331111007517	ABC transporter signature motif; other site
331111007518	Walker B; other site
331111007519	D-loop; other site
331111007520	H-loop/switch region; other site
331111007521	cytochrome c-type protein NapC; Provisional; Region: PRK10617
331111007522	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
331111007523	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
331111007524	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
331111007525	4Fe-4S binding domain; Region: Fer4_5; pfam12801
331111007526	4Fe-4S binding domain; Region: Fer4_6; pfam12837
331111007527	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
331111007528	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
331111007529	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
331111007530	[4Fe-4S] binding site [ion binding]; other site
331111007531	molybdopterin cofactor binding site; other site
331111007532	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
331111007533	molybdopterin cofactor binding site; other site
331111007534	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
331111007535	ferredoxin-type protein; Provisional; Region: PRK10194
331111007536	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
331111007537	secondary substrate binding site; other site
331111007538	primary substrate binding site; other site
331111007539	inhibition loop; other site
331111007540	dimerization interface [polypeptide binding]; other site
331111007541	malate:quinone oxidoreductase; Validated; Region: PRK05257
331111007542	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
331111007543	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
331111007544	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
331111007545	Walker A/P-loop; other site
331111007546	ATP binding site [chemical binding]; other site
331111007547	Q-loop/lid; other site
331111007548	ABC transporter signature motif; other site
331111007549	Walker B; other site
331111007550	D-loop; other site
331111007551	H-loop/switch region; other site
331111007552	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
331111007553	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
331111007554	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
331111007555	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111007556	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111007557	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
331111007558	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
331111007559	DNA binding site [nucleotide binding]
331111007560	active site
331111007561	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
331111007562	ApbE family; Region: ApbE; pfam02424
331111007563	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
331111007564	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
331111007565	trimer interface [polypeptide binding]; other site
331111007566	eyelet of channel; other site
331111007567	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
331111007568	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111007569	ATP binding site [chemical binding]; other site
331111007570	G-X-G motif; other site
331111007571	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
331111007572	putative binding surface; other site
331111007573	active site
331111007574	transcriptional regulator RcsB; Provisional; Region: PRK10840
331111007575	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111007576	active site
331111007577	phosphorylation site [posttranslational modification]
331111007578	intermolecular recognition site; other site
331111007579	dimerization interface [polypeptide binding]; other site
331111007580	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111007581	DNA binding residues [nucleotide binding]
331111007582	dimerization interface [polypeptide binding]; other site
331111007583	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
331111007584	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111007585	dimer interface [polypeptide binding]; other site
331111007586	phosphorylation site [posttranslational modification]
331111007587	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111007588	ATP binding site [chemical binding]; other site
331111007589	Mg2+ binding site [ion binding]; other site
331111007590	G-X-G motif; other site
331111007591	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
331111007592	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111007593	active site
331111007594	phosphorylation site [posttranslational modification]
331111007595	intermolecular recognition site; other site
331111007596	dimerization interface [polypeptide binding]; other site
331111007597	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4676
331111007598	Uncharacterized protein conserved in bacteria (DUF2135); Region: DUF2135; pfam09906
331111007599	Predicted secreted protein [Function unknown]; Region: COG5445
331111007600	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
331111007601	Predicted secreted protein [Function unknown]; Region: COG5445
331111007602	Stage II sporulation protein; Region: SpoIID; pfam08486
331111007603	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
331111007604	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
331111007605	MG2 domain; Region: A2M_N; pfam01835
331111007606	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
331111007607	Alpha-2-macroglobulin family; Region: A2M; pfam00207
331111007608	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
331111007609	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3234
331111007610	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4685
331111007611	DNA gyrase subunit A; Validated; Region: PRK05560
331111007612	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
331111007613	CAP-like domain; other site
331111007614	active site
331111007615	primary dimer interface [polypeptide binding]; other site
331111007616	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
331111007617	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
331111007618	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
331111007619	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
331111007620	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
331111007621	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
331111007622	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
331111007623	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111007624	S-adenosylmethionine binding site [chemical binding]; other site
331111007625	adhesin; Provisional; Region: PRK09752
331111007626	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
331111007627	Autotransporter beta-domain; Region: Autotransporter; pfam03797
331111007628	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
331111007629	ATP cone domain; Region: ATP-cone; pfam03477
331111007630	Class I ribonucleotide reductase; Region: RNR_I; cd01679
331111007631	active site
331111007632	dimer interface [polypeptide binding]; other site
331111007633	catalytic residues [active]
331111007634	effector binding site; other site
331111007635	R2 peptide binding site; other site
331111007636	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
331111007637	dimer interface [polypeptide binding]; other site
331111007638	putative radical transfer pathway; other site
331111007639	diiron center [ion binding]; other site
331111007640	tyrosyl radical; other site
331111007641	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
331111007642	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
331111007643	catalytic loop [active]
331111007644	iron binding site [ion binding]; other site
331111007645	hypothetical protein; Provisional; Region: PRK09902
331111007646	hypothetical protein; Provisional; Region: PRK09729
331111007647	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
331111007648	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
331111007649	active site
331111007650	catalytic site [active]
331111007651	metal binding site [ion binding]; metal-binding site
331111007652	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
331111007653	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111007654	putative substrate translocation pore; other site
331111007655	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
331111007656	hydroxyglutarate oxidase; Provisional; Region: PRK11728
331111007657	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
331111007658	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
331111007659	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
331111007660	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
331111007661	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
331111007662	Cysteine-rich domain; Region: CCG; pfam02754
331111007663	Cysteine-rich domain; Region: CCG; pfam02754
331111007664	hypothetical protein; Provisional; Region: PRK09956
331111007665	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
331111007666	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
331111007667	hypothetical protein; Provisional; Region: PRK03673
331111007668	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
331111007669	putative MPT binding site; other site
331111007670	Competence-damaged protein; Region: CinA; cl00666
331111007671	YfaZ precursor; Region: YfaZ; pfam07437
331111007672	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
331111007673	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
331111007674	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
331111007675	catalytic core [active]
331111007676	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
331111007677	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
331111007678	inhibitor-cofactor binding pocket; inhibition site
331111007679	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111007680	catalytic residue [active]
331111007681	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
331111007682	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
331111007683	Ligand binding site; other site
331111007684	Putative Catalytic site; other site
331111007685	DXD motif; other site
331111007686	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
331111007687	ArnA, N-terminal formyltransferase domain; Region: FMT_core_ArnA_N; cd08644
331111007688	substrate binding site [chemical binding]; other site
331111007689	cosubstrate binding site; other site
331111007690	catalytic site [active]
331111007691	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
331111007692	active site
331111007693	hexamer interface [polypeptide binding]; other site
331111007694	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
331111007695	NAD binding site [chemical binding]; other site
331111007696	substrate binding site [chemical binding]; other site
331111007697	active site
331111007698	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
331111007699	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
331111007700	putative active site [active]
331111007701	putative catalytic site [active]
331111007702	putative Zn binding site [ion binding]; other site
331111007703	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
331111007704	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
331111007705	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
331111007706	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
331111007707	signal transduction protein PmrD; Provisional; Region: PRK15450
331111007708	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
331111007709	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
331111007710	acyl-activating enzyme (AAE) consensus motif; other site
331111007711	putative AMP binding site [chemical binding]; other site
331111007712	putative active site [active]
331111007713	putative CoA binding site [chemical binding]; other site
331111007714	O-succinylbenzoate synthase; Provisional; Region: PRK05105
331111007715	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
331111007716	active site
331111007717	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
331111007718	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
331111007719	substrate binding site [chemical binding]; other site
331111007720	oxyanion hole (OAH) forming residues; other site
331111007721	trimer interface [polypeptide binding]; other site
331111007722	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
331111007723	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
331111007724	catalytic site [active]
331111007725	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
331111007726	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
331111007727	dimer interface [polypeptide binding]; other site
331111007728	tetramer interface [polypeptide binding]; other site
331111007729	PYR/PP interface [polypeptide binding]; other site
331111007730	TPP binding site [chemical binding]; other site
331111007731	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
331111007732	TPP-binding site; other site
331111007733	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
331111007734	isochorismate synthases; Region: isochor_syn; TIGR00543
331111007735	hypothetical protein; Provisional; Region: PRK10404
331111007736	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
331111007737	Coenzyme A binding pocket [chemical binding]; other site
331111007738	ribonuclease BN; Region: true_RNase_BN; TIGR02649
331111007739	deubiquitinase; Provisional; Region: PRK11836
331111007740	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
331111007741	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
331111007742	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
331111007743	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
331111007744	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
331111007745	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
331111007746	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
331111007747	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
331111007748	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
331111007749	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
331111007750	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
331111007751	4Fe-4S binding domain; Region: Fer4; pfam00037
331111007752	4Fe-4S binding domain; Region: Fer4; pfam00037
331111007753	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
331111007754	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
331111007755	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
331111007756	catalytic loop [active]
331111007757	iron binding site [ion binding]; other site
331111007758	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
331111007759	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
331111007760	[4Fe-4S] binding site [ion binding]; other site
331111007761	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
331111007762	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
331111007763	SLBB domain; Region: SLBB; pfam10531
331111007764	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
331111007765	NADH dehydrogenase subunit E; Validated; Region: PRK07539
331111007766	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
331111007767	putative dimer interface [polypeptide binding]; other site
331111007768	[2Fe-2S] cluster binding site [ion binding]; other site
331111007769	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
331111007770	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
331111007771	NADH dehydrogenase subunit D; Validated; Region: PRK06075
331111007772	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
331111007773	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
331111007774	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
331111007775	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111007776	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
331111007777	putative dimerization interface [polypeptide binding]; other site
331111007778	aminotransferase AlaT; Validated; Region: PRK09265
331111007779	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
331111007780	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111007781	homodimer interface [polypeptide binding]; other site
331111007782	catalytic residue [active]
331111007783	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
331111007784	Zn2+ binding site [ion binding]; other site
331111007785	Mg2+ binding site [ion binding]; other site
331111007786	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
331111007787	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
331111007788	TrkA-C domain; Region: TrkA_C; pfam02080
331111007789	TrkA-C domain; Region: TrkA_C; pfam02080
331111007790	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
331111007791	putative phosphatase; Provisional; Region: PRK11587
331111007792	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111007793	motif II; other site
331111007794	hypothetical protein; Validated; Region: PRK05445
331111007795	hypothetical protein; Provisional; Region: PRK01816
331111007796	propionate/acetate kinase; Provisional; Region: PRK12379
331111007797	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
331111007798	phosphate acetyltransferase; Reviewed; Region: PRK05632
331111007799	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
331111007800	DRTGG domain; Region: DRTGG; pfam07085
331111007801	phosphate acetyltransferase; Region: pta; TIGR00651
331111007802	hypothetical protein; Provisional; Region: PRK11588
331111007803	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
331111007804	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
331111007805	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
331111007806	nudix motif; other site
331111007807	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
331111007808	active site
331111007809	metal binding site [ion binding]; metal-binding site
331111007810	homotetramer interface [polypeptide binding]; other site
331111007811	glutathione S-transferase; Provisional; Region: PRK15113
331111007812	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
331111007813	C-terminal domain interface [polypeptide binding]; other site
331111007814	GSH binding site (G-site) [chemical binding]; other site
331111007815	dimer interface [polypeptide binding]; other site
331111007816	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
331111007817	N-terminal domain interface [polypeptide binding]; other site
331111007818	putative dimer interface [polypeptide binding]; other site
331111007819	putative substrate binding pocket (H-site) [chemical binding]; other site
331111007820	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
331111007821	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
331111007822	C-terminal domain interface [polypeptide binding]; other site
331111007823	GSH binding site (G-site) [chemical binding]; other site
331111007824	dimer interface [polypeptide binding]; other site
331111007825	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
331111007826	N-terminal domain interface [polypeptide binding]; other site
331111007827	putative dimer interface [polypeptide binding]; other site
331111007828	active site
331111007829	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
331111007830	homooctamer interface [polypeptide binding]; other site
331111007831	active site
331111007832	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
331111007833	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
331111007834	putative NAD(P) binding site [chemical binding]; other site
331111007835	putative active site [active]
331111007836	putative transposase; Provisional; Region: PRK09857
331111007837	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
331111007838	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
331111007839	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
331111007840	Walker A/P-loop; other site
331111007841	ATP binding site [chemical binding]; other site
331111007842	Q-loop/lid; other site
331111007843	ABC transporter signature motif; other site
331111007844	Walker B; other site
331111007845	D-loop; other site
331111007846	H-loop/switch region; other site
331111007847	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111007848	dimer interface [polypeptide binding]; other site
331111007849	conserved gate region; other site
331111007850	putative PBP binding loops; other site
331111007851	ABC-ATPase subunit interface; other site
331111007852	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
331111007853	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111007854	dimer interface [polypeptide binding]; other site
331111007855	conserved gate region; other site
331111007856	putative PBP binding loops; other site
331111007857	ABC-ATPase subunit interface; other site
331111007858	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
331111007859	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111007860	substrate binding pocket [chemical binding]; other site
331111007861	membrane-bound complex binding site; other site
331111007862	hinge residues; other site
331111007863	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
331111007864	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111007865	substrate binding pocket [chemical binding]; other site
331111007866	membrane-bound complex binding site; other site
331111007867	hinge residues; other site
331111007868	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
331111007869	Flavoprotein; Region: Flavoprotein; pfam02441
331111007870	amidophosphoribosyltransferase; Provisional; Region: PRK09246
331111007871	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
331111007872	active site
331111007873	tetramer interface [polypeptide binding]; other site
331111007874	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
331111007875	active site
331111007876	colicin V production protein; Provisional; Region: PRK10845
331111007877	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
331111007878	cell division protein DedD; Provisional; Region: PRK11633
331111007879	Sporulation related domain; Region: SPOR; pfam05036
331111007880	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
331111007881	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
331111007882	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
331111007883	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
331111007884	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
331111007885	hypothetical protein; Provisional; Region: PRK10847
331111007886	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
331111007887	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
331111007888	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
331111007889	dimerization interface 3.5A [polypeptide binding]; other site
331111007890	active site
331111007891	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
331111007892	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
331111007893	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
331111007894	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
331111007895	ligand binding site [chemical binding]; other site
331111007896	NAD binding site [chemical binding]; other site
331111007897	catalytic site [active]
331111007898	homodimer interface [polypeptide binding]; other site
331111007899	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
331111007900	putative transporter; Provisional; Region: PRK12382
331111007901	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111007902	putative substrate translocation pore; other site
331111007903	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
331111007904	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
331111007905	dimer interface [polypeptide binding]; other site
331111007906	active site
331111007907	Uncharacterized conserved protein [Function unknown]; Region: COG4121
331111007908	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
331111007909	YfcL protein; Region: YfcL; pfam08891
331111007910	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
331111007911	hypothetical protein; Provisional; Region: PRK10621
331111007912	Predicted permeases [General function prediction only]; Region: COG0730
331111007913	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
331111007914	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
331111007915	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
331111007916	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
331111007917	Tetramer interface [polypeptide binding]; other site
331111007918	active site
331111007919	FMN-binding site [chemical binding]; other site
331111007920	HemK family putative methylases; Region: hemK_fam; TIGR00536
331111007921	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111007922	S-adenosylmethionine binding site [chemical binding]; other site
331111007923	hypothetical protein; Provisional; Region: PRK04946
331111007924	Smr domain; Region: Smr; pfam01713
331111007925	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
331111007926	Fimbrial protein; Region: Fimbrial; cl01416
331111007927	Fimbrial protein; Region: Fimbrial; cl01416
331111007928	Fimbrial protein; Region: Fimbrial; cl01416
331111007929	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
331111007930	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
331111007931	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
331111007932	PapC N-terminal domain; Region: PapC_N; pfam13954
331111007933	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
331111007934	PapC C-terminal domain; Region: PapC_C; pfam13953
331111007935	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
331111007936	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
331111007937	catalytic core [active]
331111007938	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
331111007939	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
331111007940	substrate binding site [chemical binding]; other site
331111007941	oxyanion hole (OAH) forming residues; other site
331111007942	trimer interface [polypeptide binding]; other site
331111007943	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
331111007944	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
331111007945	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
331111007946	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
331111007947	dimer interface [polypeptide binding]; other site
331111007948	active site
331111007949	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
331111007950	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
331111007951	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
331111007952	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
331111007953	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
331111007954	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111007955	putative substrate translocation pore; other site
331111007956	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
331111007957	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
331111007958	putative substrate binding site [chemical binding]; other site
331111007959	putative ATP binding site [chemical binding]; other site
331111007960	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
331111007961	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
331111007962	substrate binding [chemical binding]; other site
331111007963	active site
331111007964	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
331111007965	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
331111007966	DNA binding site [nucleotide binding]
331111007967	domain linker motif; other site
331111007968	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
331111007969	Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288
331111007970	putative dimerization interface [polypeptide binding]; other site
331111007971	putative ligand binding site [chemical binding]; other site
331111007972	fructuronate transporter; Provisional; Region: PRK10034; cl15264
331111007973	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
331111007974	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
331111007975	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
331111007976	catalytic residue [active]
331111007977	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
331111007978	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111007979	putative substrate translocation pore; other site
331111007980	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111007981	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
331111007982	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
331111007983	HlyD family secretion protein; Region: HlyD_3; pfam13437
331111007984	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
331111007985	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111007986	active site
331111007987	phosphorylation site [posttranslational modification]
331111007988	intermolecular recognition site; other site
331111007989	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111007990	DNA binding residues [nucleotide binding]
331111007991	dimerization interface [polypeptide binding]; other site
331111007992	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
331111007993	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111007994	substrate binding pocket [chemical binding]; other site
331111007995	membrane-bound complex binding site; other site
331111007996	hinge residues; other site
331111007997	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111007998	substrate binding pocket [chemical binding]; other site
331111007999	membrane-bound complex binding site; other site
331111008000	hinge residues; other site
331111008001	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111008002	dimer interface [polypeptide binding]; other site
331111008003	phosphorylation site [posttranslational modification]
331111008004	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111008005	ATP binding site [chemical binding]; other site
331111008006	Mg2+ binding site [ion binding]; other site
331111008007	G-X-G motif; other site
331111008008	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111008009	active site
331111008010	phosphorylation site [posttranslational modification]
331111008011	intermolecular recognition site; other site
331111008012	dimerization interface [polypeptide binding]; other site
331111008013	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
331111008014	putative binding surface; other site
331111008015	active site
331111008016	putative CoA-transferase; Provisional; Region: PRK11430
331111008017	CoA-transferase family III; Region: CoA_transf_3; pfam02515
331111008018	putative transporter YfdV; Provisional; Region: PRK09903
331111008019	putative oxalyl-CoA decarboxylase; Validated; Region: PRK09259
331111008020	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
331111008021	PYR/PP interface [polypeptide binding]; other site
331111008022	dimer interface [polypeptide binding]; other site
331111008023	TPP binding site [chemical binding]; other site
331111008024	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
331111008025	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
331111008026	TPP-binding site; other site
331111008027	dimer interface [polypeptide binding]; other site
331111008028	formyl-coenzyme A transferase; Provisional; Region: PRK05398
331111008029	CoA-transferase family III; Region: CoA_transf_3; pfam02515
331111008030	hypothetical protein; Provisional; Region: PRK10316
331111008031	YfdX protein; Region: YfdX; pfam10938
331111008032	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
331111008033	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
331111008034	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
331111008035	putative acyl-acceptor binding pocket; other site
331111008036	aminotransferase; Validated; Region: PRK08175
331111008037	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
331111008038	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111008039	homodimer interface [polypeptide binding]; other site
331111008040	catalytic residue [active]
331111008041	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
331111008042	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
331111008043	GAF domain; Region: GAF; pfam01590
331111008044	Histidine kinase; Region: His_kinase; pfam06580
331111008045	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111008046	ATP binding site [chemical binding]; other site
331111008047	Mg2+ binding site [ion binding]; other site
331111008048	G-X-G motif; other site
331111008049	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
331111008050	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111008051	active site
331111008052	phosphorylation site [posttranslational modification]
331111008053	intermolecular recognition site; other site
331111008054	dimerization interface [polypeptide binding]; other site
331111008055	LytTr DNA-binding domain; Region: LytTR; pfam04397
331111008056	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
331111008057	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111008058	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
331111008059	dimerization domain swap beta strand [polypeptide binding]; other site
331111008060	regulatory protein interface [polypeptide binding]; other site
331111008061	active site
331111008062	regulatory phosphorylation site [posttranslational modification]; other site
331111008063	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
331111008064	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
331111008065	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
331111008066	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
331111008067	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
331111008068	active site
331111008069	phosphorylation site [posttranslational modification]
331111008070	exoaminopeptidase; Provisional; Region: PRK09961
331111008071	M42 Peptidases, also known as glutamyl aminopeptidase family; Region: M42; cd05638
331111008072	oligomer interface [polypeptide binding]; other site
331111008073	active site
331111008074	metal binding site [ion binding]; metal-binding site
331111008075	aminopeptidase; Provisional; Region: PRK09795
331111008076	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
331111008077	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
331111008078	active site
331111008079	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
331111008080	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
331111008081	active site
331111008082	P-loop; other site
331111008083	phosphorylation site [posttranslational modification]
331111008084	glucokinase, proteobacterial type; Region: glk; TIGR00749
331111008085	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
331111008086	nucleotide binding site [chemical binding]; other site
331111008087	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
331111008088	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
331111008089	Cl- selectivity filter; other site
331111008090	Cl- binding residues [ion binding]; other site
331111008091	pore gating glutamate residue; other site
331111008092	dimer interface [polypeptide binding]; other site
331111008093	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
331111008094	manganese transport protein MntH; Reviewed; Region: PRK00701
331111008095	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
331111008096	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
331111008097	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
331111008098	Nucleoside recognition; Region: Gate; pfam07670
331111008099	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
331111008100	MASE1; Region: MASE1; pfam05231
331111008101	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
331111008102	diguanylate cyclase; Region: GGDEF; smart00267
331111008103	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
331111008104	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
331111008105	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111008106	salt bridge; other site
331111008107	non-specific DNA binding site [nucleotide binding]; other site
331111008108	sequence-specific DNA binding site [nucleotide binding]; other site
331111008109	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
331111008110	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
331111008111	active site
331111008112	HIGH motif; other site
331111008113	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
331111008114	active site
331111008115	KMSKS motif; other site
331111008116	Transcriptional regulator [Transcription]; Region: LysR; COG0583
331111008117	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111008118	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
331111008119	putative dimerization interface [polypeptide binding]; other site
331111008120	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
331111008121	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
331111008122	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
331111008123	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
331111008124	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
331111008125	nucleotide binding pocket [chemical binding]; other site
331111008126	K-X-D-G motif; other site
331111008127	catalytic site [active]
331111008128	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
331111008129	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
331111008130	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
331111008131	Dimer interface [polypeptide binding]; other site
331111008132	BRCT sequence motif; other site
331111008133	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
331111008134	cell division protein ZipA; Provisional; Region: PRK03427
331111008135	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
331111008136	FtsZ protein binding site [polypeptide binding]; other site
331111008137	putative sulfate transport protein CysZ; Validated; Region: PRK04949
331111008138	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
331111008139	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
331111008140	dimer interface [polypeptide binding]; other site
331111008141	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111008142	catalytic residue [active]
331111008143	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
331111008144	dimerization domain swap beta strand [polypeptide binding]; other site
331111008145	regulatory protein interface [polypeptide binding]; other site
331111008146	active site
331111008147	regulatory phosphorylation site [posttranslational modification]; other site
331111008148	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
331111008149	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
331111008150	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
331111008151	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
331111008152	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
331111008153	HPr interaction site; other site
331111008154	glycerol kinase (GK) interaction site [polypeptide binding]; other site
331111008155	active site
331111008156	phosphorylation site [posttranslational modification]
331111008157	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
331111008158	dimer interface [polypeptide binding]; other site
331111008159	pyridoxamine kinase; Validated; Region: PRK05756
331111008160	pyridoxal binding site [chemical binding]; other site
331111008161	ATP binding site [chemical binding]; other site
331111008162	hypothetical protein; Provisional; Region: PRK10318
331111008163	cysteine synthase B; Region: cysM; TIGR01138
331111008164	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
331111008165	dimer interface [polypeptide binding]; other site
331111008166	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111008167	catalytic residue [active]
331111008168	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
331111008169	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
331111008170	Walker A/P-loop; other site
331111008171	ATP binding site [chemical binding]; other site
331111008172	Q-loop/lid; other site
331111008173	ABC transporter signature motif; other site
331111008174	Walker B; other site
331111008175	D-loop; other site
331111008176	H-loop/switch region; other site
331111008177	TOBE-like domain; Region: TOBE_3; pfam12857
331111008178	sulfate transport protein; Provisional; Region: cysT; CHL00187
331111008179	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111008180	dimer interface [polypeptide binding]; other site
331111008181	conserved gate region; other site
331111008182	putative PBP binding loops; other site
331111008183	ABC-ATPase subunit interface; other site
331111008184	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
331111008185	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111008186	dimer interface [polypeptide binding]; other site
331111008187	conserved gate region; other site
331111008188	putative PBP binding loops; other site
331111008189	ABC-ATPase subunit interface; other site
331111008190	thiosulfate transporter subunit; Provisional; Region: PRK10852
331111008191	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
331111008192	short chain dehydrogenase; Provisional; Region: PRK08226
331111008193	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
331111008194	NAD binding site [chemical binding]; other site
331111008195	homotetramer interface [polypeptide binding]; other site
331111008196	homodimer interface [polypeptide binding]; other site
331111008197	active site
331111008198	transcriptional regulator MurR; Provisional; Region: PRK15482
331111008199	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
331111008200	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
331111008201	putative active site [active]
331111008202	N-acetylmuramic acid 6-phosphate etherase; Region: TIGR00274
331111008203	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
331111008204	putative active site [active]
331111008205	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
331111008206	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
331111008207	active site turn [active]
331111008208	phosphorylation site [posttranslational modification]
331111008209	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
331111008210	putative periplasmic esterase; Provisional; Region: PRK03642
331111008211	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
331111008212	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
331111008213	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
331111008214	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
331111008215	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
331111008216	putative acetyltransferase; Provisional; Region: PRK03624
331111008217	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
331111008218	Coenzyme A binding pocket [chemical binding]; other site
331111008219	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
331111008220	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
331111008221	active site
331111008222	metal binding site [ion binding]; metal-binding site
331111008223	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
331111008224	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
331111008225	transcriptional regulator EutR; Provisional; Region: PRK10130
331111008226	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111008227	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111008228	carboxysome structural protein EutK; Provisional; Region: PRK15466
331111008229	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
331111008230	Hexamer interface [polypeptide binding]; other site
331111008231	Hexagonal pore residue; other site
331111008232	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
331111008233	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
331111008234	putative hexamer interface [polypeptide binding]; other site
331111008235	putative hexagonal pore; other site
331111008236	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
331111008237	putative hexamer interface [polypeptide binding]; other site
331111008238	putative hexagonal pore; other site
331111008239	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
331111008240	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
331111008241	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
331111008242	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
331111008243	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
331111008244	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
331111008245	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
331111008246	active site
331111008247	metal binding site [ion binding]; metal-binding site
331111008248	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
331111008249	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
331111008250	nucleotide binding site [chemical binding]; other site
331111008251	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
331111008252	putative catalytic cysteine [active]
331111008253	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
331111008254	Hexamer/Pentamer interface [polypeptide binding]; other site
331111008255	central pore; other site
331111008256	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
331111008257	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
331111008258	Hexamer interface [polypeptide binding]; other site
331111008259	Putative hexagonal pore residue; other site
331111008260	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
331111008261	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
331111008262	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
331111008263	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
331111008264	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
331111008265	G1 box; other site
331111008266	GTP/Mg2+ binding site [chemical binding]; other site
331111008267	G2 box; other site
331111008268	Switch I region; other site
331111008269	G3 box; other site
331111008270	Switch II region; other site
331111008271	G4 box; other site
331111008272	G5 box; other site
331111008273	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
331111008274	putative hexamer interface [polypeptide binding]; other site
331111008275	putative hexagonal pore; other site
331111008276	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
331111008277	Malic enzyme, N-terminal domain; Region: malic; pfam00390
331111008278	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
331111008279	putative NAD(P) binding site [chemical binding]; other site
331111008280	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
331111008281	transaldolase-like protein; Provisional; Region: PTZ00411
331111008282	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
331111008283	active site
331111008284	dimer interface [polypeptide binding]; other site
331111008285	catalytic residue [active]
331111008286	transketolase; Reviewed; Region: PRK12753
331111008287	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
331111008288	TPP-binding site [chemical binding]; other site
331111008289	dimer interface [polypeptide binding]; other site
331111008290	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
331111008291	PYR/PP interface [polypeptide binding]; other site
331111008292	dimer interface [polypeptide binding]; other site
331111008293	TPP binding site [chemical binding]; other site
331111008294	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
331111008295	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
331111008296	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
331111008297	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
331111008298	dimer interface [polypeptide binding]; other site
331111008299	ADP-ribose binding site [chemical binding]; other site
331111008300	active site
331111008301	nudix motif; other site
331111008302	metal binding site [ion binding]; metal-binding site
331111008303	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
331111008304	4Fe-4S binding domain; Region: Fer4; pfam00037
331111008305	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
331111008306	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111008307	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
331111008308	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
331111008309	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
331111008310	dimerization interface [polypeptide binding]; other site
331111008311	Histidine kinase; Region: HisKA_3; pfam07730
331111008312	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111008313	ATP binding site [chemical binding]; other site
331111008314	Mg2+ binding site [ion binding]; other site
331111008315	G-X-G motif; other site
331111008316	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
331111008317	Protein export membrane protein; Region: SecD_SecF; cl14618
331111008318	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
331111008319	ArsC family; Region: ArsC; pfam03960
331111008320	putative catalytic residues [active]
331111008321	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
331111008322	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
331111008323	metal binding site [ion binding]; metal-binding site
331111008324	dimer interface [polypeptide binding]; other site
331111008325	hypothetical protein; Provisional; Region: PRK13664
331111008326	putative hydrolase; Provisional; Region: PRK11460
331111008327	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
331111008328	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
331111008329	Helicase; Region: Helicase_RecD; pfam05127
331111008330	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
331111008331	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
331111008332	Predicted metalloprotease [General function prediction only]; Region: COG2321
331111008333	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
331111008334	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
331111008335	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
331111008336	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
331111008337	ATP binding site [chemical binding]; other site
331111008338	active site
331111008339	substrate binding site [chemical binding]; other site
331111008340	lipoprotein; Provisional; Region: PRK11679
331111008341	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
331111008342	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
331111008343	dihydrodipicolinate synthase; Region: dapA; TIGR00674
331111008344	dimer interface [polypeptide binding]; other site
331111008345	active site
331111008346	catalytic residue [active]
331111008347	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
331111008348	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
331111008349	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
331111008350	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
331111008351	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
331111008352	catalytic triad [active]
331111008353	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
331111008354	4Fe-4S binding domain; Region: Fer4; pfam00037
331111008355	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
331111008356	NADH dehydrogenase; Region: NADHdh; cl00469
331111008357	hydrogenase 4 membrane subunit; Provisional; Region: hyfE; PRK11492
331111008358	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
331111008359	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
331111008360	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
331111008361	hydrogenase 4 subunit H; Validated; Region: PRK08222
331111008362	4Fe-4S binding domain; Region: Fer4; pfam00037
331111008363	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
331111008364	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
331111008365	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains [Transcription / Signal transduction mechanisms]; Region: FhlA; COG3604
331111008366	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
331111008367	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111008368	Walker A motif; other site
331111008369	ATP binding site [chemical binding]; other site
331111008370	Walker B motif; other site
331111008371	arginine finger; other site
331111008372	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
331111008373	putative formate transporter; Provisional; Region: focB; PRK09713
331111008374	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
331111008375	Domain of unknown function DUF20; Region: UPF0118; pfam01594
331111008376	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
331111008377	Peptidase family M48; Region: Peptidase_M48; cl12018
331111008378	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
331111008379	DNA replication initiation factor; Provisional; Region: PRK08084
331111008380	uracil transporter; Provisional; Region: PRK10720
331111008381	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
331111008382	active site
331111008383	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
331111008384	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
331111008385	dimerization interface [polypeptide binding]; other site
331111008386	putative ATP binding site [chemical binding]; other site
331111008387	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
331111008388	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
331111008389	active site
331111008390	substrate binding site [chemical binding]; other site
331111008391	cosubstrate binding site; other site
331111008392	catalytic site [active]
331111008393	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
331111008394	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
331111008395	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
331111008396	Catalytic C-terminal domain, first repeat, of prokaryotic polyphosphate kinase 1 and similar proteins; Region: PLDc_PPK1_C1; cd09114
331111008397	domain interface [polypeptide binding]; other site
331111008398	active site
331111008399	catalytic site [active]
331111008400	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
331111008401	putative active site [active]
331111008402	catalytic site [active]
331111008403	exopolyphosphatase; Provisional; Region: PRK10854
331111008404	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
331111008405	MASE1; Region: MASE1; pfam05231
331111008406	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
331111008407	diguanylate cyclase; Region: GGDEF; smart00267
331111008408	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
331111008409	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
331111008410	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
331111008411	GMP synthase; Reviewed; Region: guaA; PRK00074
331111008412	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
331111008413	AMP/PPi binding site [chemical binding]; other site
331111008414	candidate oxyanion hole; other site
331111008415	catalytic triad [active]
331111008416	potential glutamine specificity residues [chemical binding]; other site
331111008417	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
331111008418	ATP Binding subdomain [chemical binding]; other site
331111008419	Ligand Binding sites [chemical binding]; other site
331111008420	Dimerization subdomain; other site
331111008421	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
331111008422	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
331111008423	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
331111008424	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
331111008425	active site
331111008426	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
331111008427	GTP-binding protein Der; Reviewed; Region: PRK00093
331111008428	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
331111008429	G1 box; other site
331111008430	GTP/Mg2+ binding site [chemical binding]; other site
331111008431	Switch I region; other site
331111008432	G2 box; other site
331111008433	Switch II region; other site
331111008434	G3 box; other site
331111008435	G4 box; other site
331111008436	G5 box; other site
331111008437	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
331111008438	G1 box; other site
331111008439	GTP/Mg2+ binding site [chemical binding]; other site
331111008440	Switch I region; other site
331111008441	G2 box; other site
331111008442	G3 box; other site
331111008443	Switch II region; other site
331111008444	G4 box; other site
331111008445	G5 box; other site
331111008446	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
331111008447	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cd00216
331111008448	Trp docking motif [polypeptide binding]; other site
331111008449	active site
331111008450	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
331111008451	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
331111008452	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
331111008453	dimer interface [polypeptide binding]; other site
331111008454	motif 1; other site
331111008455	active site
331111008456	motif 2; other site
331111008457	motif 3; other site
331111008458	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
331111008459	anticodon binding site; other site
331111008460	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
331111008461	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
331111008462	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
331111008463	cytoskeletal protein RodZ; Provisional; Region: PRK10856
331111008464	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111008465	non-specific DNA binding site [nucleotide binding]; other site
331111008466	salt bridge; other site
331111008467	sequence-specific DNA binding site [nucleotide binding]; other site
331111008468	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
331111008469	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
331111008470	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111008471	FeS/SAM binding site; other site
331111008472	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
331111008473	active site
331111008474	multimer interface [polypeptide binding]; other site
331111008475	penicillin-binding protein 1C; Provisional; Region: PRK11240
331111008476	Transglycosylase; Region: Transgly; pfam00912
331111008477	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
331111008478	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
331111008479	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
331111008480	MG2 domain; Region: A2M_N; pfam01835
331111008481	Alpha-2-macroglobulin family; Region: A2M; pfam00207
331111008482	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
331111008483	surface patch; other site
331111008484	thioester region; other site
331111008485	specificity defining residues; other site
331111008486	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
331111008487	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
331111008488	active site residue [active]
331111008489	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
331111008490	active site residue [active]
331111008491	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
331111008492	aminopeptidase B; Provisional; Region: PRK05015
331111008493	Peptidase; Region: DUF3663; pfam12404
331111008494	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
331111008495	interface (dimer of trimers) [polypeptide binding]; other site
331111008496	Substrate-binding/catalytic site; other site
331111008497	Zn-binding sites [ion binding]; other site
331111008498	hypothetical protein; Provisional; Region: PRK10721
331111008499	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
331111008500	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
331111008501	catalytic loop [active]
331111008502	iron binding site [ion binding]; other site
331111008503	chaperone protein HscA; Provisional; Region: hscA; PRK05183
331111008504	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
331111008505	nucleotide binding site [chemical binding]; other site
331111008506	putative NEF/HSP70 interaction site [polypeptide binding]; other site
331111008507	SBD interface [polypeptide binding]; other site
331111008508	co-chaperone HscB; Provisional; Region: hscB; PRK05014
331111008509	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
331111008510	HSP70 interaction site [polypeptide binding]; other site
331111008511	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
331111008512	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
331111008513	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
331111008514	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
331111008515	trimerization site [polypeptide binding]; other site
331111008516	active site
331111008517	cysteine desulfurase; Provisional; Region: PRK14012
331111008518	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
331111008519	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
331111008520	catalytic residue [active]
331111008521	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
331111008522	Rrf2 family protein; Region: rrf2_super; TIGR00738
331111008523	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
331111008524	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
331111008525	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
331111008526	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
331111008527	active site
331111008528	dimerization interface [polypeptide binding]; other site
331111008529	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
331111008530	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
331111008531	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
331111008532	PRD domain; Region: PRD; pfam00874
331111008533	PRD domain; Region: PRD; pfam00874
331111008534	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
331111008535	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111008536	putative substrate translocation pore; other site
331111008537	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
331111008538	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111008539	The C-terminal substrate binding domain of LysR-type transcriptional regulator HcaR in involved in 3-phenylpropionic acid catabolism, contains the type2 periplasmic binding fold; Region: PBP2_HcaR; cd08450
331111008540	putative dimerization interface [polypeptide binding]; other site
331111008541	putative substrate binding pocket [chemical binding]; other site
331111008542	Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667
331111008543	inter-subunit interface; other site
331111008544	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
331111008545	[2Fe-2S] cluster binding site [ion binding]; other site
331111008546	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Provisional; Region: PRK06200
331111008547	cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)-like, classical (c) SDRs; Region: BphB-like_SDR_c; cd05348
331111008548	NAD binding site [chemical binding]; other site
331111008549	active site
331111008550	phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754
331111008551	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111008552	Predicted membrane protein [Function unknown]; Region: COG2259
331111008553	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
331111008554	active site
331111008555	catalytic residues [active]
331111008556	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
331111008557	L-threonine dehydrogenase (TDH)-like; Region: THR_DH_like; cd08239
331111008558	putative NAD(P) binding site [chemical binding]; other site
331111008559	catalytic Zn binding site [ion binding]; other site
331111008560	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
331111008561	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
331111008562	TM-ABC transporter signature motif; other site
331111008563	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
331111008564	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
331111008565	Walker A/P-loop; other site
331111008566	ATP binding site [chemical binding]; other site
331111008567	Q-loop/lid; other site
331111008568	ABC transporter signature motif; other site
331111008569	Walker B; other site
331111008570	D-loop; other site
331111008571	H-loop/switch region; other site
331111008572	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
331111008573	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
331111008574	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
331111008575	ligand binding site [chemical binding]; other site
331111008576	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
331111008577	TPR motif; other site
331111008578	Tetratricopeptide repeat; Region: TPR_16; pfam13432
331111008579	binding surface
331111008580	TPR repeat; Region: TPR_11; pfam13414
331111008581	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
331111008582	TPR motif; other site
331111008583	binding surface
331111008584	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
331111008585	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
331111008586	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
331111008587	nucleotide binding site [chemical binding]; other site
331111008588	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
331111008589	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
331111008590	dimer interface [polypeptide binding]; other site
331111008591	active site
331111008592	glycine-pyridoxal phosphate binding site [chemical binding]; other site
331111008593	folate binding site [chemical binding]; other site
331111008594	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
331111008595	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
331111008596	heme-binding site [chemical binding]; other site
331111008597	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
331111008598	FAD binding pocket [chemical binding]; other site
331111008599	FAD binding motif [chemical binding]; other site
331111008600	phosphate binding motif [ion binding]; other site
331111008601	beta-alpha-beta structure motif; other site
331111008602	NAD binding pocket [chemical binding]; other site
331111008603	Heme binding  pocket [chemical binding]; other site
331111008604	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
331111008605	Nitrogen regulatory protein P-II; Region: P-II; smart00938
331111008606	response regulator GlrR; Provisional; Region: PRK15115
331111008607	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111008608	active site
331111008609	phosphorylation site [posttranslational modification]
331111008610	intermolecular recognition site; other site
331111008611	dimerization interface [polypeptide binding]; other site
331111008612	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111008613	Walker A motif; other site
331111008614	ATP binding site [chemical binding]; other site
331111008615	Walker B motif; other site
331111008616	arginine finger; other site
331111008617	hypothetical protein; Provisional; Region: PRK10722
331111008618	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
331111008619	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111008620	dimer interface [polypeptide binding]; other site
331111008621	phosphorylation site [posttranslational modification]
331111008622	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111008623	ATP binding site [chemical binding]; other site
331111008624	Mg2+ binding site [ion binding]; other site
331111008625	G-X-G motif; other site
331111008626	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
331111008627	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
331111008628	dimerization interface [polypeptide binding]; other site
331111008629	ATP binding site [chemical binding]; other site
331111008630	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
331111008631	dimerization interface [polypeptide binding]; other site
331111008632	ATP binding site [chemical binding]; other site
331111008633	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
331111008634	putative active site [active]
331111008635	catalytic triad [active]
331111008636	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
331111008637	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111008638	substrate binding pocket [chemical binding]; other site
331111008639	membrane-bound complex binding site; other site
331111008640	hinge residues; other site
331111008641	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
331111008642	N-acetyl-D-glucosamine binding site [chemical binding]; other site
331111008643	catalytic residue [active]
331111008644	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
331111008645	nucleoside/Zn binding site; other site
331111008646	dimer interface [polypeptide binding]; other site
331111008647	catalytic motif [active]
331111008648	hypothetical protein; Provisional; Region: PRK11590
331111008649	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
331111008650	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
331111008651	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
331111008652	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
331111008653	putative active site [active]
331111008654	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
331111008655	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
331111008656	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
331111008657	active site
331111008658	hydrophilic channel; other site
331111008659	dimerization interface [polypeptide binding]; other site
331111008660	catalytic residues [active]
331111008661	active site lid [active]
331111008662	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
331111008663	Recombination protein O N terminal; Region: RecO_N; pfam11967
331111008664	Recombination protein O C terminal; Region: RecO_C; pfam02565
331111008665	GTPase Era; Reviewed; Region: era; PRK00089
331111008666	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
331111008667	G1 box; other site
331111008668	GTP/Mg2+ binding site [chemical binding]; other site
331111008669	Switch I region; other site
331111008670	G2 box; other site
331111008671	Switch II region; other site
331111008672	G3 box; other site
331111008673	G4 box; other site
331111008674	G5 box; other site
331111008675	KH domain; Region: KH_2; pfam07650
331111008676	ribonuclease III; Reviewed; Region: rnc; PRK00102
331111008677	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
331111008678	dimerization interface [polypeptide binding]; other site
331111008679	active site
331111008680	metal binding site [ion binding]; metal-binding site
331111008681	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
331111008682	dsRNA binding site [nucleotide binding]; other site
331111008683	signal peptidase I; Provisional; Region: PRK10861
331111008684	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
331111008685	Catalytic site [active]
331111008686	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
331111008687	GTP-binding protein LepA; Provisional; Region: PRK05433
331111008688	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
331111008689	G1 box; other site
331111008690	putative GEF interaction site [polypeptide binding]; other site
331111008691	GTP/Mg2+ binding site [chemical binding]; other site
331111008692	Switch I region; other site
331111008693	G2 box; other site
331111008694	G3 box; other site
331111008695	Switch II region; other site
331111008696	G4 box; other site
331111008697	G5 box; other site
331111008698	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
331111008699	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
331111008700	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
331111008701	SoxR reducing system protein RseC; Provisional; Region: PRK10862
331111008702	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
331111008703	anti-sigma E factor; Provisional; Region: rseB; PRK09455
331111008704	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
331111008705	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
331111008706	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
331111008707	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
331111008708	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
331111008709	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
331111008710	DNA binding residues [nucleotide binding]
331111008711	L-aspartate oxidase; Provisional; Region: PRK09077
331111008712	L-aspartate oxidase; Provisional; Region: PRK06175
331111008713	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
331111008714	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
331111008715	Methyltransferase domain; Region: Methyltransf_26; pfam13659
331111008716	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
331111008717	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
331111008718	ATP binding site [chemical binding]; other site
331111008719	Mg++ binding site [ion binding]; other site
331111008720	motif III; other site
331111008721	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111008722	nucleotide binding region [chemical binding]; other site
331111008723	ATP-binding site [chemical binding]; other site
331111008724	Transcriptional regulator [Transcription]; Region: LysR; COG0583
331111008725	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111008726	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
331111008727	dimerization interface [polypeptide binding]; other site
331111008728	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
331111008729	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
331111008730	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
331111008731	ligand binding site [chemical binding]; other site
331111008732	active site
331111008733	UGI interface [polypeptide binding]; other site
331111008734	catalytic site [active]
331111008735	putative methyltransferase; Provisional; Region: PRK10864
331111008736	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
331111008737	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
331111008738	thioredoxin 2; Provisional; Region: PRK10996
331111008739	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
331111008740	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
331111008741	catalytic residues [active]
331111008742	Uncharacterized conserved protein [Function unknown]; Region: COG3148
331111008743	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
331111008744	CoA binding domain; Region: CoA_binding_2; pfam13380
331111008745	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
331111008746	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
331111008747	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
331111008748	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
331111008749	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
331111008750	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
331111008751	domain interface [polypeptide binding]; other site
331111008752	putative active site [active]
331111008753	catalytic site [active]
331111008754	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
331111008755	domain interface [polypeptide binding]; other site
331111008756	putative active site [active]
331111008757	catalytic site [active]
331111008758	lipoprotein; Provisional; Region: PRK10759
331111008759	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
331111008760	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111008761	putative substrate translocation pore; other site
331111008762	protein disaggregation chaperone; Provisional; Region: PRK10865
331111008763	Clp amino terminal domain; Region: Clp_N; pfam02861
331111008764	Clp amino terminal domain; Region: Clp_N; pfam02861
331111008765	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111008766	Walker A motif; other site
331111008767	ATP binding site [chemical binding]; other site
331111008768	Walker B motif; other site
331111008769	arginine finger; other site
331111008770	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111008771	Walker A motif; other site
331111008772	ATP binding site [chemical binding]; other site
331111008773	Walker B motif; other site
331111008774	arginine finger; other site
331111008775	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
331111008776	hypothetical protein; Provisional; Region: PRK10723
331111008777	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
331111008778	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
331111008779	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
331111008780	RNA binding surface [nucleotide binding]; other site
331111008781	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
331111008782	active site
331111008783	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
331111008784	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
331111008785	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
331111008786	30S subunit binding site; other site
331111008787	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
331111008788	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
331111008789	Prephenate dehydratase; Region: PDT; pfam00800
331111008790	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
331111008791	putative L-Phe binding site [chemical binding]; other site
331111008792	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
331111008793	chorismate mutase domain of T-protein; Region: CM_T; TIGR01799
331111008794	prephenate dehydrogenase; Validated; Region: PRK08507
331111008795	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
331111008796	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
331111008797	lipoprotein; Provisional; Region: PRK11443
331111008798	Protein of unknown function (DUF2799); Region: DUF2799; pfam10973
331111008799	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
331111008800	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
331111008801	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111008802	metal binding site [ion binding]; metal-binding site
331111008803	active site
331111008804	I-site; other site
331111008805	putative outer membrane lipoprotein; Provisional; Region: PRK09967
331111008806	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
331111008807	ligand binding site [chemical binding]; other site
331111008808	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
331111008809	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
331111008810	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
331111008811	RimM N-terminal domain; Region: RimM; pfam01782
331111008812	PRC-barrel domain; Region: PRC; pfam05239
331111008813	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
331111008814	signal recognition particle protein; Provisional; Region: PRK10867
331111008815	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
331111008816	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
331111008817	P loop; other site
331111008818	GTP binding site [chemical binding]; other site
331111008819	Signal peptide binding domain; Region: SRP_SPB; pfam02978
331111008820	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
331111008821	hypothetical protein; Provisional; Region: PRK11573
331111008822	Domain of unknown function DUF21; Region: DUF21; pfam01595
331111008823	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
331111008824	Transporter associated domain; Region: CorC_HlyC; smart01091
331111008825	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
331111008826	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
331111008827	dimer interface [polypeptide binding]; other site
331111008828	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
331111008829	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
331111008830	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
331111008831	recombination and repair protein; Provisional; Region: PRK10869
331111008832	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
331111008833	Walker A/P-loop; other site
331111008834	ATP binding site [chemical binding]; other site
331111008835	Q-loop/lid; other site
331111008836	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
331111008837	Q-loop/lid; other site
331111008838	ABC transporter signature motif; other site
331111008839	Walker B; other site
331111008840	D-loop; other site
331111008841	H-loop/switch region; other site
331111008842	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
331111008843	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
331111008844	hypothetical protein; Validated; Region: PRK01777
331111008845	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
331111008846	putative coenzyme Q binding site [chemical binding]; other site
331111008847	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
331111008848	SmpB-tmRNA interface; other site
331111008849	integrase; Provisional; Region: PRK09692
331111008850	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
331111008851	active site
331111008852	Int/Topo IB signature motif; other site
331111008853	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
331111008854	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
331111008855	catalytic residues [active]
331111008856	catalytic nucleophile [active]
331111008857	Recombinase; Region: Recombinase; pfam07508
331111008858	ParB-like nuclease domain; Region: ParBc; pfam02195
331111008859	RepB plasmid partitioning protein; Region: RepB; pfam07506
331111008860	ParB-like nuclease domain; Region: ParB; smart00470
331111008861	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
331111008862	RepB plasmid partitioning protein; Region: RepB; pfam07506
331111008863	HsdM N-terminal domain; Region: HsdM_N; pfam12161
331111008864	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
331111008865	Methyltransferase domain; Region: Methyltransf_26; pfam13659
331111008866	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
331111008867	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
331111008868	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
331111008869	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
331111008870	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
331111008871	ATP binding site [chemical binding]; other site
331111008872	putative Mg++ binding site [ion binding]; other site
331111008873	Domain of unknown function (DUF3387); Region: DUF3387; pfam11867
331111008874	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
331111008875	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
331111008876	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
331111008877	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
331111008878	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
331111008879	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
331111008880	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
331111008881	Putative cell-wall binding lipoprotein; Region: YkyA; pfam10368
331111008882	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
331111008883	Helix-turn-helix domain; Region: HTH_38; pfam13936
331111008884	Integrase core domain; Region: rve; pfam00665
331111008885	Integrase core domain; Region: rve_3; cl15866
331111008886	transposase/IS protein; Provisional; Region: PRK09183
331111008887	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111008888	Walker A motif; other site
331111008889	ATP binding site [chemical binding]; other site
331111008890	Walker B motif; other site
331111008891	arginine finger; other site
331111008892	MarR family; Region: MarR_2; cl17246
331111008893	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
331111008894	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
331111008895	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
331111008896	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
331111008897	SIR2-like domain; Region: SIR2_2; pfam13289
331111008898	Autotransporter beta-domain; Region: Autotransporter; smart00869
331111008899	Transposase; Region: HTH_Tnp_1; pfam01527
331111008900	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111008901	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111008902	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111008903	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
331111008904	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
331111008905	active site
331111008906	catalytic site [active]
331111008907	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; cl02706
331111008908	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
331111008909	substrate binding pocket [chemical binding]; other site
331111008910	active site
331111008911	iron coordination sites [ion binding]; other site
331111008912	Predicted dehydrogenase [General function prediction only]; Region: COG0579
331111008913	hydroxyglutarate oxidase; Provisional; Region: PRK11728
331111008914	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
331111008915	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
331111008916	tetramerization interface [polypeptide binding]; other site
331111008917	NAD(P) binding site [chemical binding]; other site
331111008918	catalytic residues [active]
331111008919	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
331111008920	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
331111008921	inhibitor-cofactor binding pocket; inhibition site
331111008922	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111008923	catalytic residue [active]
331111008924	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
331111008925	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
331111008926	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111008927	DNA-binding site [nucleotide binding]; DNA binding site
331111008928	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
331111008929	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
331111008930	bacterial OsmY and nodulation domain; Region: BON; smart00749
331111008931	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
331111008932	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
331111008933	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
331111008934	dimerization interface [polypeptide binding]; other site
331111008935	putative DNA binding site [nucleotide binding]; other site
331111008936	Transcriptional regulators [Transcription]; Region: MarR; COG1846
331111008937	putative Zn2+ binding site [ion binding]; other site
331111008938	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, and similar uncharacterized putative rhodanese-related sulfurtransferases; Region: RHOD_YgaP; cd01527
331111008939	active site residue [active]
331111008940	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
331111008941	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
331111008942	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
331111008943	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
331111008944	hypothetical protein; Provisional; Region: PRK10556
331111008945	hypothetical protein; Provisional; Region: PRK10132
331111008946	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
331111008947	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
331111008948	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
331111008949	Class I ribonucleotide reductase; Region: RNR_I; cd01679
331111008950	active site
331111008951	dimer interface [polypeptide binding]; other site
331111008952	catalytic residues [active]
331111008953	effector binding site; other site
331111008954	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
331111008955	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
331111008956	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
331111008957	dimer interface [polypeptide binding]; other site
331111008958	putative radical transfer pathway; other site
331111008959	diiron center [ion binding]; other site
331111008960	tyrosyl radical; other site
331111008961	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
331111008962	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
331111008963	Walker A/P-loop; other site
331111008964	ATP binding site [chemical binding]; other site
331111008965	Q-loop/lid; other site
331111008966	ABC transporter signature motif; other site
331111008967	Walker B; other site
331111008968	D-loop; other site
331111008969	H-loop/switch region; other site
331111008970	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
331111008971	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
331111008972	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111008973	dimer interface [polypeptide binding]; other site
331111008974	conserved gate region; other site
331111008975	putative PBP binding loops; other site
331111008976	ABC-ATPase subunit interface; other site
331111008977	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
331111008978	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
331111008979	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
331111008980	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111008981	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
331111008982	putative L-valine exporter; Provisional; Region: PRK10408
331111008983	transcriptional repressor MprA; Provisional; Region: PRK10870
331111008984	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
331111008985	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
331111008986	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
331111008987	HlyD family secretion protein; Region: HlyD_3; pfam13437
331111008988	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
331111008989	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111008990	putative substrate translocation pore; other site
331111008991	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111008992	S-ribosylhomocysteinase; Provisional; Region: PRK02260
331111008993	glutamate--cysteine ligase; Provisional; Region: PRK02107
331111008994	Predicted membrane protein [Function unknown]; Region: COG1238
331111008995	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
331111008996	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111008997	motif II; other site
331111008998	carbon storage regulator; Provisional; Region: PRK01712
331111008999	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
331111009000	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
331111009001	motif 1; other site
331111009002	active site
331111009003	motif 2; other site
331111009004	motif 3; other site
331111009005	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
331111009006	DHHA1 domain; Region: DHHA1; pfam02272
331111009007	recombination regulator RecX; Reviewed; Region: recX; PRK00117
331111009008	recombinase A; Provisional; Region: recA; PRK09354
331111009009	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
331111009010	hexamer interface [polypeptide binding]; other site
331111009011	Walker A motif; other site
331111009012	ATP binding site [chemical binding]; other site
331111009013	Walker B motif; other site
331111009014	hypothetical protein; Validated; Region: PRK03661
331111009015	Transglycosylase SLT domain; Region: SLT_2; pfam13406
331111009016	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
331111009017	N-acetyl-D-glucosamine binding site [chemical binding]; other site
331111009018	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
331111009019	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
331111009020	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
331111009021	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
331111009022	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
331111009023	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
331111009024	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
331111009025	putative NAD(P) binding site [chemical binding]; other site
331111009026	active site
331111009027	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
331111009028	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
331111009029	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
331111009030	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
331111009031	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
331111009032	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
331111009033	putative active site [active]
331111009034	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
331111009035	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
331111009036	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
331111009037	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111009038	Walker A motif; other site
331111009039	ATP binding site [chemical binding]; other site
331111009040	Walker B motif; other site
331111009041	arginine finger; other site
331111009042	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
331111009043	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
331111009044	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
331111009045	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
331111009046	iron binding site [ion binding]; other site
331111009047	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
331111009048	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
331111009049	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111009050	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
331111009051	Acylphosphatase; Region: Acylphosphatase; pfam00708
331111009052	HypF finger; Region: zf-HYPF; pfam07503
331111009053	HypF finger; Region: zf-HYPF; pfam07503
331111009054	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
331111009055	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
331111009056	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
331111009057	Transcriptional regulators [Transcription]; Region: PurR; COG1609
331111009058	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
331111009059	DNA binding site [nucleotide binding]
331111009060	domain linker motif; other site
331111009061	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
331111009062	dimerization interface (closed form) [polypeptide binding]; other site
331111009063	ligand binding site [chemical binding]; other site
331111009064	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
331111009065	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
331111009066	active site turn [active]
331111009067	phosphorylation site [posttranslational modification]
331111009068	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
331111009069	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
331111009070	beta-galactosidase; Region: BGL; TIGR03356
331111009071	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
331111009072	Transposase; Region: DEDD_Tnp_IS110; pfam01548
331111009073	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
331111009074	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111009075	non-specific DNA binding site [nucleotide binding]; other site
331111009076	salt bridge; other site
331111009077	sequence-specific DNA binding site [nucleotide binding]; other site
331111009078	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
331111009079	nickel binding site [ion binding]; other site
331111009080	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
331111009081	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
331111009082	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
331111009083	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
331111009084	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
331111009085	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
331111009086	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
331111009087	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
331111009088	NADH dehydrogenase; Region: NADHdh; cl00469
331111009089	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
331111009090	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
331111009091	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
331111009092	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
331111009093	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
331111009094	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
331111009095	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
331111009096	hydrogenase assembly chaperone; Provisional; Region: PRK10409
331111009097	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
331111009098	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
331111009099	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
331111009100	dimerization interface [polypeptide binding]; other site
331111009101	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
331111009102	ATP binding site [chemical binding]; other site
331111009103	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
331111009104	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
331111009105	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
331111009106	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111009107	Walker A motif; other site
331111009108	ATP binding site [chemical binding]; other site
331111009109	Walker B motif; other site
331111009110	arginine finger; other site
331111009111	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
331111009112	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
331111009113	HNH endonuclease; Region: HNH_2; pfam13391
331111009114	chromosome segregation protein; Provisional; Region: PRK03918
331111009115	Transposase; Region: HTH_Tnp_1; cl17663
331111009116	putative transposase OrfB; Reviewed; Region: PHA02517
331111009117	HTH-like domain; Region: HTH_21; pfam13276
331111009118	Integrase core domain; Region: rve; pfam00665
331111009119	Integrase core domain; Region: rve_2; pfam13333
331111009120	RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_I; cd01646
331111009121	putative active site [active]
331111009122	putative NTP binding site [chemical binding]; other site
331111009123	putative nucleic acid binding site [nucleotide binding]; other site
331111009124	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
331111009125	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
331111009126	active site
331111009127	Int/Topo IB signature motif; other site
331111009128	DNA binding site [nucleotide binding]
331111009129	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
331111009130	MutS domain I; Region: MutS_I; pfam01624
331111009131	MutS domain II; Region: MutS_II; pfam05188
331111009132	MutS domain III; Region: MutS_III; pfam05192
331111009133	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
331111009134	Walker A/P-loop; other site
331111009135	ATP binding site [chemical binding]; other site
331111009136	Q-loop/lid; other site
331111009137	ABC transporter signature motif; other site
331111009138	Walker B; other site
331111009139	D-loop; other site
331111009140	H-loop/switch region; other site
331111009141	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
331111009142	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
331111009143	active site
331111009144	metal binding site [ion binding]; metal-binding site
331111009145	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
331111009146	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
331111009147	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
331111009148	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
331111009149	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
331111009150	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
331111009151	putative aldolase; Validated; Region: PRK08130
331111009152	active site
331111009153	intersubunit interface [polypeptide binding]; other site
331111009154	Zn2+ binding site [ion binding]; other site
331111009155	hypothetical protein; Provisional; Region: PRK09989
331111009156	putative transporter; Provisional; Region: PRK09821
331111009157	GntP family permease; Region: GntP_permease; pfam02447
331111009158	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
331111009159	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
331111009160	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
331111009161	Flavoprotein; Region: Flavoprotein; pfam02441
331111009162	MarR family; Region: MarR_2; cl17246
331111009163	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
331111009164	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
331111009165	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
331111009166	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
331111009167	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
331111009168	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
331111009169	DNA binding residues [nucleotide binding]
331111009170	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
331111009171	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
331111009172	Peptidase family M23; Region: Peptidase_M23; pfam01551
331111009173	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
331111009174	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111009175	S-adenosylmethionine binding site [chemical binding]; other site
331111009176	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
331111009177	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
331111009178	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
331111009179	Permutation of conserved domain; other site
331111009180	active site
331111009181	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
331111009182	homotrimer interaction site [polypeptide binding]; other site
331111009183	zinc binding site [ion binding]; other site
331111009184	CDP-binding sites; other site
331111009185	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
331111009186	substrate binding site; other site
331111009187	dimer interface; other site
331111009188	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
331111009189	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
331111009190	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
331111009191	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
331111009192	ligand-binding site [chemical binding]; other site
331111009193	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
331111009194	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
331111009195	CysD dimerization site [polypeptide binding]; other site
331111009196	G1 box; other site
331111009197	putative GEF interaction site [polypeptide binding]; other site
331111009198	GTP/Mg2+ binding site [chemical binding]; other site
331111009199	Switch I region; other site
331111009200	G2 box; other site
331111009201	G3 box; other site
331111009202	Switch II region; other site
331111009203	G4 box; other site
331111009204	G5 box; other site
331111009205	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
331111009206	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
331111009207	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
331111009208	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
331111009209	Active Sites [active]
331111009210	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
331111009211	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
331111009212	metal binding site [ion binding]; metal-binding site
331111009213	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
331111009214	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09664
331111009215	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
331111009216	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
331111009217	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
331111009218	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09670
331111009219	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
331111009220	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
331111009221	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
331111009222	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
331111009223	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
331111009224	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
331111009225	Active Sites [active]
331111009226	sulfite reductase subunit beta; Provisional; Region: PRK13504
331111009227	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
331111009228	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
331111009229	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
331111009230	Flavodoxin; Region: Flavodoxin_1; pfam00258
331111009231	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
331111009232	FAD binding pocket [chemical binding]; other site
331111009233	FAD binding motif [chemical binding]; other site
331111009234	catalytic residues [active]
331111009235	NAD binding pocket [chemical binding]; other site
331111009236	phosphate binding motif [ion binding]; other site
331111009237	beta-alpha-beta structure motif; other site
331111009238	6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a...; Region: PTPS; cd00470
331111009239	homohexamer interface [polypeptide binding]; other site
331111009240	putative substrate stabilizing pore; other site
331111009241	pterin binding site; other site
331111009242	putative oxidoreductase FixC; Provisional; Region: PRK10157
331111009243	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
331111009244	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
331111009245	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
331111009246	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
331111009247	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
331111009248	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
331111009249	Ligand binding site [chemical binding]; other site
331111009250	Electron transfer flavoprotein domain; Region: ETF; pfam01012
331111009251	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
331111009252	benzoate transport; Region: 2A0115; TIGR00895
331111009253	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111009254	putative substrate translocation pore; other site
331111009255	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
331111009256	FAD binding domain; Region: FAD_binding_4; pfam01565
331111009257	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
331111009258	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
331111009259	NADP binding site [chemical binding]; other site
331111009260	homodimer interface [polypeptide binding]; other site
331111009261	active site
331111009262	Major Facilitator Superfamily; Region: MFS_1; pfam07690
331111009263	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111009264	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
331111009265	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
331111009266	nucleotide binding site [chemical binding]; other site
331111009267	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
331111009268	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
331111009269	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
331111009270	Repair protein; Region: Repair_PSII; pfam04536
331111009271	enolase; Provisional; Region: eno; PRK00077
331111009272	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
331111009273	dimer interface [polypeptide binding]; other site
331111009274	metal binding site [ion binding]; metal-binding site
331111009275	substrate binding pocket [chemical binding]; other site
331111009276	CTP synthetase; Validated; Region: pyrG; PRK05380
331111009277	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
331111009278	Catalytic site [active]
331111009279	active site
331111009280	UTP binding site [chemical binding]; other site
331111009281	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
331111009282	active site
331111009283	putative oxyanion hole; other site
331111009284	catalytic triad [active]
331111009285	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
331111009286	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
331111009287	homodimer interface [polypeptide binding]; other site
331111009288	metal binding site [ion binding]; metal-binding site
331111009289	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
331111009290	homodimer interface [polypeptide binding]; other site
331111009291	active site
331111009292	putative chemical substrate binding site [chemical binding]; other site
331111009293	metal binding site [ion binding]; metal-binding site
331111009294	toxin MazF; Provisional; Region: PRK09907
331111009295	antitoxin MazE; Provisional; Region: PRK09798
331111009296	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
331111009297	HD domain; Region: HD_4; pfam13328
331111009298	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
331111009299	synthetase active site [active]
331111009300	NTP binding site [chemical binding]; other site
331111009301	metal binding site [ion binding]; metal-binding site
331111009302	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
331111009303	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
331111009304	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
331111009305	TRAM domain; Region: TRAM; pfam01938
331111009306	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111009307	S-adenosylmethionine binding site [chemical binding]; other site
331111009308	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
331111009309	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
331111009310	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
331111009311	dimerization interface [polypeptide binding]; other site
331111009312	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111009313	dimer interface [polypeptide binding]; other site
331111009314	phosphorylation site [posttranslational modification]
331111009315	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111009316	ATP binding site [chemical binding]; other site
331111009317	Mg2+ binding site [ion binding]; other site
331111009318	G-X-G motif; other site
331111009319	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
331111009320	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111009321	active site
331111009322	phosphorylation site [posttranslational modification]
331111009323	intermolecular recognition site; other site
331111009324	dimerization interface [polypeptide binding]; other site
331111009325	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
331111009326	putative binding surface; other site
331111009327	active site
331111009328	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
331111009329	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
331111009330	active site
331111009331	tetramer interface [polypeptide binding]; other site
331111009332	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
331111009333	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
331111009334	active site
331111009335	tetramer interface [polypeptide binding]; other site
331111009336	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111009337	D-galactonate transporter; Region: 2A0114; TIGR00893
331111009338	putative substrate translocation pore; other site
331111009339	flavodoxin; Provisional; Region: PRK08105
331111009340	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
331111009341	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
331111009342	probable active site [active]
331111009343	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
331111009344	SecY interacting protein Syd; Provisional; Region: PRK04968
331111009345	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
331111009346	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
331111009347	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
331111009348	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
331111009349	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
331111009350	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
331111009351	serine transporter; Region: stp; TIGR00814
331111009352	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
331111009353	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
331111009354	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
331111009355	flap endonuclease-like protein; Provisional; Region: PRK09482
331111009356	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
331111009357	active site
331111009358	metal binding site 1 [ion binding]; metal-binding site
331111009359	putative 5' ssDNA interaction site; other site
331111009360	metal binding site 3; metal-binding site
331111009361	metal binding site 2 [ion binding]; metal-binding site
331111009362	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
331111009363	putative DNA binding site [nucleotide binding]; other site
331111009364	putative metal binding site [ion binding]; other site
331111009365	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
331111009366	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
331111009367	dimer interface [polypeptide binding]; other site
331111009368	active site
331111009369	metal binding site [ion binding]; metal-binding site
331111009370	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
331111009371	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
331111009372	intersubunit interface [polypeptide binding]; other site
331111009373	active site
331111009374	Zn2+ binding site [ion binding]; other site
331111009375	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
331111009376	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111009377	putative substrate translocation pore; other site
331111009378	L-fucose isomerase; Provisional; Region: fucI; PRK10991
331111009379	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
331111009380	hexamer (dimer of trimers) interface [polypeptide binding]; other site
331111009381	trimer interface [polypeptide binding]; other site
331111009382	substrate binding site [chemical binding]; other site
331111009383	Mn binding site [ion binding]; other site
331111009384	L-fuculokinase; Provisional; Region: PRK10331
331111009385	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
331111009386	nucleotide binding site [chemical binding]; other site
331111009387	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
331111009388	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
331111009389	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
331111009390	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
331111009391	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
331111009392	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
331111009393	hypothetical protein; Provisional; Region: PRK10873
331111009394	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
331111009395	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111009396	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
331111009397	dimerization interface [polypeptide binding]; other site
331111009398	substrate binding pocket [chemical binding]; other site
331111009399	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
331111009400	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
331111009401	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
331111009402	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
331111009403	catalytic residue [active]
331111009404	CsdA-binding activator; Provisional; Region: PRK15019
331111009405	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
331111009406	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
331111009407	putative ATP binding site [chemical binding]; other site
331111009408	putative substrate interface [chemical binding]; other site
331111009409	murein transglycosylase A; Provisional; Region: mltA; PRK11162
331111009410	MltA specific insert domain; Region: MltA; pfam03562
331111009411	3D domain; Region: 3D; pfam06725
331111009412	Protein of unknown function (DUF770); Region: DUF770; pfam05591
331111009413	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
331111009414	Protein of unknown function (DUF877); Region: DUF877; pfam05943
331111009415	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
331111009416	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
331111009417	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
331111009418	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
331111009419	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
331111009420	ligand binding site [chemical binding]; other site
331111009421	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
331111009422	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
331111009423	Clp amino terminal domain; Region: Clp_N; pfam02861
331111009424	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111009425	Walker A motif; other site
331111009426	ATP binding site [chemical binding]; other site
331111009427	Walker B motif; other site
331111009428	arginine finger; other site
331111009429	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111009430	Walker A motif; other site
331111009431	ATP binding site [chemical binding]; other site
331111009432	Walker B motif; other site
331111009433	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
331111009434	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
331111009435	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
331111009436	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
331111009437	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
331111009438	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253
331111009439	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
331111009440	N-acetyl-D-glucosamine binding site [chemical binding]; other site
331111009441	catalytic residue [active]
331111009442	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
331111009443	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
331111009444	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
331111009445	ImpA domain protein; Region: DUF3702; pfam12486
331111009446	ROS/MUCR transcriptional regulator protein; Region: ROS_MUCR; pfam05443
331111009447	AMIN domain; Region: AMIN; pfam11741
331111009448	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
331111009449	active site
331111009450	metal binding site [ion binding]; metal-binding site
331111009451	N-acetylglutamate synthase; Validated; Region: PRK05279
331111009452	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
331111009453	putative feedback inhibition sensing region; other site
331111009454	putative nucleotide binding site [chemical binding]; other site
331111009455	putative substrate binding site [chemical binding]; other site
331111009456	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
331111009457	Coenzyme A binding pocket [chemical binding]; other site
331111009458	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
331111009459	AAA domain; Region: AAA_30; pfam13604
331111009460	Family description; Region: UvrD_C_2; pfam13538
331111009461	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
331111009462	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
331111009463	protease3; Provisional; Region: PRK15101
331111009464	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
331111009465	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
331111009466	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
331111009467	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
331111009468	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
331111009469	hypothetical protein; Provisional; Region: PRK10332
331111009470	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
331111009471	hypothetical protein; Provisional; Region: PRK11521
331111009472	hypothetical protein; Provisional; Region: PRK10557
331111009473	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
331111009474	hypothetical protein; Provisional; Region: PRK10506
331111009475	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
331111009476	thymidylate synthase; Reviewed; Region: thyA; PRK01827
331111009477	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
331111009478	dimerization interface [polypeptide binding]; other site
331111009479	active site
331111009480	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
331111009481	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
331111009482	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
331111009483	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
331111009484	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
331111009485	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
331111009486	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
331111009487	putative active site [active]
331111009488	Ap4A binding site [chemical binding]; other site
331111009489	nudix motif; other site
331111009490	putative metal binding site [ion binding]; other site
331111009491	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
331111009492	putative DNA-binding cleft [nucleotide binding]; other site
331111009493	putative DNA clevage site; other site
331111009494	molecular lever; other site
331111009495	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
331111009496	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
331111009497	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
331111009498	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
331111009499	active site
331111009500	catalytic tetrad [active]
331111009501	lysophospholipid transporter LplT; Provisional; Region: PRK11195
331111009502	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111009503	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
331111009504	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
331111009505	putative acyl-acceptor binding pocket; other site
331111009506	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
331111009507	acyl-activating enzyme (AAE) consensus motif; other site
331111009508	putative AMP binding site [chemical binding]; other site
331111009509	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
331111009510	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
331111009511	DNA binding site [nucleotide binding]
331111009512	domain linker motif; other site
331111009513	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
331111009514	dimerization interface (closed form) [polypeptide binding]; other site
331111009515	ligand binding site [chemical binding]; other site
331111009516	diaminopimelate decarboxylase; Provisional; Region: PRK11165
331111009517	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
331111009518	active site
331111009519	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
331111009520	substrate binding site [chemical binding]; other site
331111009521	catalytic residues [active]
331111009522	dimer interface [polypeptide binding]; other site
331111009523	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
331111009524	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111009525	The C-terminal substrate binding domain of LysR, transcriptional regulator for lysine biosynthesis, contains the type 2 periplasmic binding fold; Region: PBP2_LysR; cd08456
331111009526	putative dimerization interface [polypeptide binding]; other site
331111009527	putative racemase; Provisional; Region: PRK10200
331111009528	aspartate racemase; Region: asp_race; TIGR00035
331111009529	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
331111009530	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111009531	putative substrate translocation pore; other site
331111009532	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111009533	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
331111009534	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
331111009535	NADP binding site [chemical binding]; other site
331111009536	homodimer interface [polypeptide binding]; other site
331111009537	active site
331111009538	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
331111009539	putative acyltransferase; Provisional; Region: PRK05790
331111009540	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
331111009541	dimer interface [polypeptide binding]; other site
331111009542	active site
331111009543	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
331111009544	serine transporter; Region: stp; TIGR00814
331111009545	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
331111009546	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
331111009547	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
331111009548	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
331111009549	Tetratricopeptide repeat; Region: TPR_3; pfam07720
331111009550	Tetratricopeptide repeat; Region: TPR_3; pfam07720
331111009551	transcriptional regulator; Provisional; Region: PRK11906
331111009552	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
331111009553	DNA binding site [nucleotide binding]
331111009554	Tetratricopeptide repeat; Region: TPR_2; pfam07719
331111009555	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
331111009556	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111009557	DNA binding residues [nucleotide binding]
331111009558	dimerization interface [polypeptide binding]; other site
331111009559	invasion protein OrgB; Provisional; Region: PRK15322
331111009560	Type III secretory pathway, lipoprotein EscJ [Intracellular trafficking and secretion]; Region: EscJ; COG4669
331111009561	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327; cl12363
331111009562	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
331111009563	type III secretion system protein SpaS; Validated; Region: PRK08156
331111009564	type III secretion protein SpaR/YscT/HrcT; Region: fliR_like_III; TIGR01401
331111009565	type III secretion system protein SpaQ; Provisional; Region: PRK15333
331111009566	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
331111009567	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
331111009568	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
331111009569	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
331111009570	Peptidase family M23; Region: Peptidase_M23; pfam01551
331111009571	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
331111009572	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
331111009573	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
331111009574	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
331111009575	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
331111009576	xanthine dehydrogenase subunit XdhC; Provisional; Region: PRK09908
331111009577	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
331111009578	catalytic loop [active]
331111009579	iron binding site [ion binding]; other site
331111009580	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
331111009581	GAF domain; Region: GAF; cl17456
331111009582	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
331111009583	PAS domain; Region: PAS; smart00091
331111009584	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111009585	Walker A motif; other site
331111009586	ATP binding site [chemical binding]; other site
331111009587	Walker B motif; other site
331111009588	arginine finger; other site
331111009589	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
331111009590	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
331111009591	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
331111009592	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
331111009593	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
331111009594	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
331111009595	catalytic residue [active]
331111009596	peptidase; Reviewed; Region: PRK13004
331111009597	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
331111009598	putative metal binding site [ion binding]; other site
331111009599	putative dimer interface [polypeptide binding]; other site
331111009600	D-hydantoinase; Region: D-hydantoinase; TIGR02033
331111009601	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
331111009602	tetramer interface [polypeptide binding]; other site
331111009603	active site
331111009604	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
331111009605	carbamate kinase; Reviewed; Region: PRK12686
331111009606	putative substrate binding site [chemical binding]; other site
331111009607	homodimer interface [polypeptide binding]; other site
331111009608	nucleotide binding site [chemical binding]; other site
331111009609	nucleotide binding site [chemical binding]; other site
331111009610	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
331111009611	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
331111009612	XdhC Rossmann domain; Region: XdhC_C; pfam13478
331111009613	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
331111009614	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
331111009615	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
331111009616	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
331111009617	Ligand binding site; other site
331111009618	metal-binding site
331111009619	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
331111009620	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
331111009621	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
331111009622	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111009623	putative selenium metabolism protein SsnA; Region: Se_ssnA; TIGR03314
331111009624	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
331111009625	active site
331111009626	putative substrate binding pocket [chemical binding]; other site
331111009627	probable selenate reductase, FAD-binding subunit; Region: Se_sel_red_FAD; TIGR03312
331111009628	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
331111009629	putative hypoxanthine oxidase; Provisional; Region: PRK09800
331111009630	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
331111009631	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
331111009632	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
331111009633	uracil-xanthine permease; Region: ncs2; TIGR00801
331111009634	guanine deaminase; Provisional; Region: PRK09228
331111009635	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
331111009636	active site
331111009637	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
331111009638	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
331111009639	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12809
331111009640	4Fe-4S binding domain; Region: Fer4; pfam00037
331111009641	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
331111009642	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111009643	xanthine permease; Region: pbuX; TIGR03173
331111009644	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
331111009645	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
331111009646	active site
331111009647	metal binding site [ion binding]; metal-binding site
331111009648	nudix motif; other site
331111009649	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
331111009650	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
331111009651	dimer interface [polypeptide binding]; other site
331111009652	putative anticodon binding site; other site
331111009653	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
331111009654	motif 1; other site
331111009655	active site
331111009656	motif 2; other site
331111009657	motif 3; other site
331111009658	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
331111009659	DHH family; Region: DHH; pfam01368
331111009660	DHHA1 domain; Region: DHHA1; pfam02272
331111009661	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
331111009662	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
331111009663	dimerization domain [polypeptide binding]; other site
331111009664	dimer interface [polypeptide binding]; other site
331111009665	catalytic residues [active]
331111009666	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
331111009667	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
331111009668	active site
331111009669	Int/Topo IB signature motif; other site
331111009670	flavodoxin FldB; Provisional; Region: PRK12359
331111009671	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
331111009672	hypothetical protein; Provisional; Region: PRK10878
331111009673	putative global regulator; Reviewed; Region: PRK09559
331111009674	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
331111009675	hemolysin; Provisional; Region: PRK15087
331111009676	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
331111009677	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
331111009678	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
331111009679	beta-galactosidase; Region: BGL; TIGR03356
331111009680	putative NAD(P)-binding oxidoreductase; Provisional; Region: PRK09730
331111009681	classical (c) SDRs; Region: SDR_c; cd05233
331111009682	NAD(P) binding site [chemical binding]; other site
331111009683	active site
331111009684	glycine dehydrogenase; Provisional; Region: PRK05367
331111009685	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
331111009686	tetramer interface [polypeptide binding]; other site
331111009687	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111009688	catalytic residue [active]
331111009689	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
331111009690	tetramer interface [polypeptide binding]; other site
331111009691	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111009692	catalytic residue [active]
331111009693	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
331111009694	lipoyl attachment site [posttranslational modification]; other site
331111009695	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
331111009696	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
331111009697	oxidoreductase; Provisional; Region: PRK08013
331111009698	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
331111009699	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
331111009700	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
331111009701	proline aminopeptidase P II; Provisional; Region: PRK10879
331111009702	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
331111009703	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
331111009704	active site
331111009705	hypothetical protein; Reviewed; Region: PRK01736
331111009706	Z-ring-associated protein; Provisional; Region: PRK10972
331111009707	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
331111009708	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
331111009709	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
331111009710	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
331111009711	ligand binding site [chemical binding]; other site
331111009712	NAD binding site [chemical binding]; other site
331111009713	tetramer interface [polypeptide binding]; other site
331111009714	catalytic site [active]
331111009715	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
331111009716	L-serine binding site [chemical binding]; other site
331111009717	ACT domain interface; other site
331111009718	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
331111009719	tetramer (dimer of dimers) interface [polypeptide binding]; other site
331111009720	active site
331111009721	dimer interface [polypeptide binding]; other site
331111009722	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
331111009723	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111009724	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
331111009725	putative dimerization interface [polypeptide binding]; other site
331111009726	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
331111009727	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
331111009728	active site
331111009729	substrate binding site [chemical binding]; other site
331111009730	coenzyme B12 binding site [chemical binding]; other site
331111009731	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
331111009732	B12 binding site [chemical binding]; other site
331111009733	cobalt ligand [ion binding]; other site
331111009734	membrane ATPase/protein kinase; Provisional; Region: PRK09435
331111009735	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
331111009736	Walker A; other site
331111009737	methylmalonyl-CoA decarboxylase; Provisional; Region: PRK11423
331111009738	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
331111009739	substrate binding site [chemical binding]; other site
331111009740	oxyanion hole (OAH) forming residues; other site
331111009741	trimer interface [polypeptide binding]; other site
331111009742	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111009743	Transcriptional regulator [Transcription]; Region: LysR; COG0583
331111009744	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
331111009745	dimerization interface [polypeptide binding]; other site
331111009746	Uncharacterized conserved protein [Function unknown]; Region: COG2968
331111009747	oxidative stress defense protein; Provisional; Region: PRK11087
331111009748	arginine exporter protein; Provisional; Region: PRK09304
331111009749	mechanosensitive channel MscS; Provisional; Region: PRK10334
331111009750	Mechanosensitive ion channel; Region: MS_channel; pfam00924
331111009751	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
331111009752	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
331111009753	active site
331111009754	intersubunit interface [polypeptide binding]; other site
331111009755	zinc binding site [ion binding]; other site
331111009756	Na+ binding site [ion binding]; other site
331111009757	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
331111009758	Phosphoglycerate kinase; Region: PGK; pfam00162
331111009759	substrate binding site [chemical binding]; other site
331111009760	hinge regions; other site
331111009761	ADP binding site [chemical binding]; other site
331111009762	catalytic site [active]
331111009763	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
331111009764	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
331111009765	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
331111009766	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
331111009767	trimer interface [polypeptide binding]; other site
331111009768	putative Zn binding site [ion binding]; other site
331111009769	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
331111009770	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
331111009771	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
331111009772	Walker A/P-loop; other site
331111009773	ATP binding site [chemical binding]; other site
331111009774	Q-loop/lid; other site
331111009775	ABC transporter signature motif; other site
331111009776	Walker B; other site
331111009777	D-loop; other site
331111009778	H-loop/switch region; other site
331111009779	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
331111009780	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
331111009781	Walker A/P-loop; other site
331111009782	ATP binding site [chemical binding]; other site
331111009783	Q-loop/lid; other site
331111009784	ABC transporter signature motif; other site
331111009785	Walker B; other site
331111009786	D-loop; other site
331111009787	H-loop/switch region; other site
331111009788	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
331111009789	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
331111009790	active site
331111009791	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
331111009792	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
331111009793	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
331111009794	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
331111009795	putative active site [active]
331111009796	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
331111009797	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
331111009798	putative NAD(P) binding site [chemical binding]; other site
331111009799	catalytic Zn binding site [ion binding]; other site
331111009800	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
331111009801	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
331111009802	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
331111009803	active site
331111009804	P-loop; other site
331111009805	phosphorylation site [posttranslational modification]
331111009806	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
331111009807	active site
331111009808	phosphorylation site [posttranslational modification]
331111009809	transketolase; Reviewed; Region: PRK12753
331111009810	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
331111009811	TPP-binding site [chemical binding]; other site
331111009812	dimer interface [polypeptide binding]; other site
331111009813	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
331111009814	PYR/PP interface [polypeptide binding]; other site
331111009815	dimer interface [polypeptide binding]; other site
331111009816	TPP binding site [chemical binding]; other site
331111009817	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
331111009818	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
331111009819	Protein of unknown function (DUF1341); Region: DUF1341; cl06211
331111009820	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
331111009821	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
331111009822	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
331111009823	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
331111009824	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
331111009825	active site
331111009826	phosphorylation site [posttranslational modification]
331111009827	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
331111009828	active pocket/dimerization site; other site
331111009829	active site
331111009830	phosphorylation site [posttranslational modification]
331111009831	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
331111009832	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111009833	Walker A motif; other site
331111009834	ATP binding site [chemical binding]; other site
331111009835	Walker B motif; other site
331111009836	arginine finger; other site
331111009837	Transcriptional antiterminator [Transcription]; Region: COG3933
331111009838	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
331111009839	active site
331111009840	active pocket/dimerization site; other site
331111009841	phosphorylation site [posttranslational modification]
331111009842	PRD domain; Region: PRD; pfam00874
331111009843	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
331111009844	agmatinase; Region: agmatinase; TIGR01230
331111009845	oligomer interface [polypeptide binding]; other site
331111009846	putative active site [active]
331111009847	Mn binding site [ion binding]; other site
331111009848	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
331111009849	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
331111009850	dimer interface [polypeptide binding]; other site
331111009851	active site
331111009852	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
331111009853	catalytic residues [active]
331111009854	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
331111009855	Virulence promoting factor; Region: YqgB; pfam11036
331111009856	S-adenosylmethionine synthetase; Validated; Region: PRK05250
331111009857	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
331111009858	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
331111009859	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
331111009860	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
331111009861	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111009862	putative substrate translocation pore; other site
331111009863	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111009864	hypothetical protein; Provisional; Region: PRK04860
331111009865	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
331111009866	DNA-specific endonuclease I; Provisional; Region: PRK15137
331111009867	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
331111009868	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
331111009869	RNA methyltransferase, RsmE family; Region: TIGR00046
331111009870	glutathione synthetase; Provisional; Region: PRK05246
331111009871	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
331111009872	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
331111009873	hypothetical protein; Validated; Region: PRK00228
331111009874	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
331111009875	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
331111009876	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
331111009877	Walker A motif; other site
331111009878	ATP binding site [chemical binding]; other site
331111009879	Walker B motif; other site
331111009880	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
331111009881	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
331111009882	catalytic residue [active]
331111009883	YGGT family; Region: YGGT; pfam02325
331111009884	YGGT family; Region: YGGT; pfam02325
331111009885	hypothetical protein; Validated; Region: PRK05090
331111009886	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
331111009887	active site
331111009888	dimerization interface [polypeptide binding]; other site
331111009889	HemN family oxidoreductase; Provisional; Region: PRK05660
331111009890	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111009891	FeS/SAM binding site; other site
331111009892	HemN C-terminal domain; Region: HemN_C; pfam06969
331111009893	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
331111009894	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
331111009895	homodimer interface [polypeptide binding]; other site
331111009896	active site
331111009897	hypothetical protein; Provisional; Region: PRK10626
331111009898	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
331111009899	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
331111009900	hypothetical protein; Provisional; Region: PRK11702
331111009901	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
331111009902	adenine DNA glycosylase; Provisional; Region: PRK10880
331111009903	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
331111009904	minor groove reading motif; other site
331111009905	helix-hairpin-helix signature motif; other site
331111009906	substrate binding pocket [chemical binding]; other site
331111009907	active site
331111009908	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
331111009909	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
331111009910	DNA binding and oxoG recognition site [nucleotide binding]
331111009911	oxidative damage protection protein; Provisional; Region: PRK05408
331111009912	murein transglycosylase C; Provisional; Region: mltC; PRK11671
331111009913	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
331111009914	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
331111009915	N-acetyl-D-glucosamine binding site [chemical binding]; other site
331111009916	catalytic residue [active]
331111009917	nucleoside transporter; Region: 2A0110; TIGR00889
331111009918	ornithine decarboxylase; Provisional; Region: PRK13578
331111009919	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
331111009920	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
331111009921	homodimer interface [polypeptide binding]; other site
331111009922	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111009923	catalytic residue [active]
331111009924	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
331111009925	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
331111009926	integrase; Provisional; Region: PRK09692
331111009927	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
331111009928	active site
331111009929	Int/Topo IB signature motif; other site
331111009930	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
331111009931	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
331111009932	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
331111009933	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
331111009934	Protein of unknown function (DUF2931); Region: DUF2931; pfam11153
331111009935	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
331111009936	ATP binding site [chemical binding]; other site
331111009937	putative Mg++ binding site [ion binding]; other site
331111009938	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111009939	nucleotide binding region [chemical binding]; other site
331111009940	ATP-binding site [chemical binding]; other site
331111009941	SNF-7-like protein; Provisional; Region: PTZ00464
331111009942	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
331111009943	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111009944	Walker A motif; other site
331111009945	ATP binding site [chemical binding]; other site
331111009946	Walker B motif; other site
331111009947	arginine finger; other site
331111009948	Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like_2; cd04847
331111009949	active site
331111009950	catalytic triad [active]
331111009951	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
331111009952	DNA methylase; Region: N6_N4_Mtase; pfam01555
331111009953	DNA methylase; Region: N6_N4_Mtase; pfam01555
331111009954	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
331111009955	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
331111009956	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
331111009957	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
331111009958	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
331111009959	putative active site [active]
331111009960	putative NTP binding site [chemical binding]; other site
331111009961	putative nucleic acid binding site [nucleotide binding]; other site
331111009962	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
331111009963	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111009964	Transposase; Region: HTH_Tnp_1; cl17663
331111009965	McrBC 5-methylcytosine restriction system component; Region: McrBC; pfam10117
331111009966	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
331111009967	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
331111009968	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
331111009969	Haemolysin expression modulating protein; Region: HHA; pfam05321
331111009970	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
331111009971	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
331111009972	DNA-binding interface [nucleotide binding]; DNA binding site
331111009973	Integrase core domain; Region: rve; pfam00665
331111009974	transposase/IS protein; Provisional; Region: PRK09183
331111009975	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111009976	Walker A motif; other site
331111009977	ATP binding site [chemical binding]; other site
331111009978	Walker B motif; other site
331111009979	arginine finger; other site
331111009980	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
331111009981	Helix-turn-helix domain; Region: HTH_38; pfam13936
331111009982	Integrase core domain; Region: rve; pfam00665
331111009983	Integrase core domain; Region: rve_3; cl15866
331111009984	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
331111009985	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111009986	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
331111009987	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
331111009988	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111009989	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111009990	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111009991	Transposase; Region: HTH_Tnp_1; pfam01527
331111009992	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111009993	Predicted GTPase [General function prediction only]; Region: COG3596
331111009994	YfjP GTPase; Region: YfjP; cd11383
331111009995	G1 box; other site
331111009996	GTP/Mg2+ binding site [chemical binding]; other site
331111009997	Switch I region; other site
331111009998	G2 box; other site
331111009999	Switch II region; other site
331111010000	G3 box; other site
331111010001	G4 box; other site
331111010002	G5 box; other site
331111010003	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
331111010004	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
331111010005	hypothetical protein; Provisional; Region: PRK09945
331111010006	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
331111010007	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
331111010008	Autotransporter beta-domain; Region: Autotransporter; smart00869
331111010009	Domain of unknown function (DUF932); Region: DUF932; pfam06067
331111010010	Antirestriction protein; Region: Antirestrict; pfam03230
331111010011	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
331111010012	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
331111010013	MPN+ (JAMM) motif; other site
331111010014	Zinc-binding site [ion binding]; other site
331111010015	Protein of unknown function (DUF987); Region: DUF987; pfam06174
331111010016	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
331111010017	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
331111010018	Herpes virus major capsid protein; Region: Herpes_MCP; pfam03122
331111010019	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
331111010020	Methyltransferase domain; Region: Methyltransf_27; pfam13708
331111010021	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
331111010022	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235
331111010023	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
331111010024	active site
331111010025	catalytic residues [active]
331111010026	DNA binding site [nucleotide binding]
331111010027	Int/Topo IB signature motif; other site
331111010028	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
331111010029	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
331111010030	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
331111010031	Family description; Region: UvrD_C_2; pfam13538
331111010032	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
331111010033	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
331111010034	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
331111010035	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
331111010036	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
331111010037	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
331111010038	Part of AAA domain; Region: AAA_19; pfam13245
331111010039	Family description; Region: UvrD_C_2; pfam13538
331111010040	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
331111010041	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
331111010042	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
331111010043	putative active site [active]
331111010044	putative metal-binding site [ion binding]; other site
331111010045	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
331111010046	Transposase; Region: HTH_Tnp_1; pfam01527
331111010047	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111010048	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111010049	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111010050	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
331111010051	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
331111010052	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111010053	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
331111010054	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
331111010055	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111010056	transposase/IS protein; Provisional; Region: PRK09183
331111010057	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111010058	Walker A motif; other site
331111010059	ATP binding site [chemical binding]; other site
331111010060	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
331111010061	Helix-turn-helix domain; Region: HTH_38; pfam13936
331111010062	Integrase core domain; Region: rve; pfam00665
331111010063	Integrase core domain; Region: rve_3; cl15866
331111010064	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
331111010065	replicative DNA helicase; Region: DnaB; TIGR00665
331111010066	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
331111010067	Walker A motif; other site
331111010068	ATP binding site [chemical binding]; other site
331111010069	Walker B motif; other site
331111010070	DNA binding loops [nucleotide binding]
331111010071	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
331111010072	AAA domain; Region: AAA_31; pfam13614
331111010073	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
331111010074	P-loop; other site
331111010075	Magnesium ion binding site [ion binding]; other site
331111010076	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
331111010077	integrase; Provisional; Region: PRK09692
331111010078	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
331111010079	active site
331111010080	Int/Topo IB signature motif; other site
331111010081	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
331111010082	DNA binding site [nucleotide binding]
331111010083	domain linker motif; other site
331111010084	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
331111010085	Ligand-binding domain of DNA transcription repressors specific for raffinose (RafR) and alpha-glucosides (AglR) which are members of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_AglR_RafR_like; cd06271
331111010086	ligand binding site [chemical binding]; other site
331111010087	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
331111010088	Melibiase; Region: Melibiase; pfam02065
331111010089	galactoside permease; Reviewed; Region: lacY; PRK09528
331111010090	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111010091	putative substrate translocation pore; other site
331111010092	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
331111010093	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
331111010094	substrate binding [chemical binding]; other site
331111010095	active site
331111010096	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
331111010097	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
331111010098	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111010099	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
331111010100	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
331111010101	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111010102	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111010103	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111010104	Transposase; Region: HTH_Tnp_1; pfam01527
331111010105	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111010106	H-NS histone family; Region: Histone_HNS; pfam00816
331111010107	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
331111010108	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
331111010109	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
331111010110	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
331111010111	Predicted GTPase [General function prediction only]; Region: COG3596
331111010112	YfjP GTPase; Region: YfjP; cd11383
331111010113	G1 box; other site
331111010114	GTP/Mg2+ binding site [chemical binding]; other site
331111010115	Switch I region; other site
331111010116	G2 box; other site
331111010117	Switch II region; other site
331111010118	G3 box; other site
331111010119	G4 box; other site
331111010120	G5 box; other site
331111010121	HTH domain; Region: HTH_11; cl17392
331111010122	WYL domain; Region: WYL; pfam13280
331111010123	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
331111010124	Domain of unknown function (DUF932); Region: DUF932; pfam06067
331111010125	Antirestriction protein; Region: Antirestrict; pfam03230
331111010126	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
331111010127	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
331111010128	MPN+ (JAMM) motif; other site
331111010129	Zinc-binding site [ion binding]; other site
331111010130	Protein of unknown function (DUF987); Region: DUF987; pfam06174
331111010131	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
331111010132	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
331111010133	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
331111010134	Methyltransferase domain; Region: Methyltransf_27; pfam13708
331111010135	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
331111010136	putative general secretion pathway protein YghD; Provisional; Region: PRK09731
331111010137	type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709
331111010138	GspL-like protein; Provisional; Region: PRK09662
331111010139	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
331111010140	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
331111010141	type II secretion system protein J; Region: gspJ; TIGR01711
331111010142	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
331111010143	type II secretion system protein I; Region: gspI; TIGR01707
331111010144	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
331111010145	Prokaryotic N-terminal methylation motif; Region: N_methyl; pfam07963
331111010146	Type II transport protein GspH; Region: GspH; pfam12019
331111010147	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
331111010148	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
331111010149	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
331111010150	type II secretion system protein F; Region: GspF; TIGR02120
331111010151	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
331111010152	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
331111010153	type II secretion system protein E; Region: type_II_gspE; TIGR02533
331111010154	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
331111010155	Walker A motif; other site
331111010156	ATP binding site [chemical binding]; other site
331111010157	Walker B motif; other site
331111010158	type II secretion system protein D; Region: type_II_gspD; TIGR02517
331111010159	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
331111010160	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
331111010161	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
331111010162	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
331111010163	putative type II secretion protein GspC; Provisional; Region: PRK09681
331111010164	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
331111010165	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
331111010166	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
331111010167	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
331111010168	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
331111010169	Domain of unknown function (DUF4092); Region: DUF4092; pfam13322
331111010170	Peptidase M60-like family; Region: M60-like; pfam13402
331111010171	glycolate transporter; Provisional; Region: PRK09695
331111010172	L-lactate permease; Region: Lactate_perm; cl00701
331111010173	Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate...; Region: malate_synt_G; cd00728
331111010174	active site
331111010175	hypothetical protein; Provisional; Region: PRK09732
331111010176	glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274
331111010177	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
331111010178	Cysteine-rich domain; Region: CCG; pfam02754
331111010179	Cysteine-rich domain; Region: CCG; pfam02754
331111010180	glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282
331111010181	FAD binding domain; Region: FAD_binding_4; pfam01565
331111010182	glycolate oxidase subunit GlcD; Provisional; Region: PRK11230
331111010183	FAD binding domain; Region: FAD_binding_4; pfam01565
331111010184	DNA-binding transcriptional regulator GlcC; Provisional; Region: PRK09990
331111010185	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111010186	DNA-binding site [nucleotide binding]; DNA binding site
331111010187	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
331111010188	acyl-CoA synthetase; Validated; Region: PRK09192
331111010189	Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931
331111010190	acyl-activating enzyme (AAE) consensus motif; other site
331111010191	active site
331111010192	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
331111010193	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
331111010194	NAD(P) binding site [chemical binding]; other site
331111010195	active site
331111010196	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
331111010197	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
331111010198	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
331111010199	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
331111010200	catalytic residue [active]
331111010201	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
331111010202	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
331111010203	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
331111010204	Predicted permeases [General function prediction only]; Region: COG0795
331111010205	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; pfam09695
331111010206	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
331111010207	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
331111010208	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
331111010209	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
331111010210	active site
331111010211	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
331111010212	TMP-binding site; other site
331111010213	ATP-binding site [chemical binding]; other site
331111010214	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
331111010215	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
331111010216	TMP-binding site; other site
331111010217	ATP-binding site [chemical binding]; other site
331111010218	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
331111010219	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
331111010220	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
331111010221	CHAP domain; Region: CHAP; pfam05257
331111010222	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
331111010223	putative S-transferase; Provisional; Region: PRK11752
331111010224	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
331111010225	C-terminal domain interface [polypeptide binding]; other site
331111010226	GSH binding site (G-site) [chemical binding]; other site
331111010227	dimer interface [polypeptide binding]; other site
331111010228	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
331111010229	dimer interface [polypeptide binding]; other site
331111010230	N-terminal domain interface [polypeptide binding]; other site
331111010231	active site
331111010232	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
331111010233	Transposase; Region: DEDD_Tnp_IS110; pfam01548
331111010234	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
331111010235	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
331111010236	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
331111010237	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
331111010238	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
331111010239	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
331111010240	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
331111010241	putative substrate-binding site; other site
331111010242	nickel binding site [ion binding]; other site
331111010243	hydrogenase 2 large subunit; Provisional; Region: PRK10467
331111010244	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
331111010245	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
331111010246	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
331111010247	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
331111010248	4Fe-4S binding domain; Region: Fer4_6; pfam12837
331111010249	hydrogenase 2 small subunit; Provisional; Region: PRK10468
331111010250	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
331111010251	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
331111010252	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
331111010253	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
331111010254	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
331111010255	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
331111010256	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
331111010257	active site
331111010258	catalytic tetrad [active]
331111010259	hypothetical protein; Provisional; Region: PRK05208
331111010260	oxidoreductase; Provisional; Region: PRK07985
331111010261	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
331111010262	NAD binding site [chemical binding]; other site
331111010263	metal binding site [ion binding]; metal-binding site
331111010264	active site
331111010265	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
331111010266	biopolymer transport protein ExbD; Provisional; Region: PRK11267
331111010267	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
331111010268	biopolymer transport protein ExbB; Provisional; Region: PRK10414
331111010269	cystathionine beta-lyase; Provisional; Region: PRK08114
331111010270	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
331111010271	homodimer interface [polypeptide binding]; other site
331111010272	substrate-cofactor binding pocket; other site
331111010273	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111010274	catalytic residue [active]
331111010275	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
331111010276	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
331111010277	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
331111010278	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
331111010279	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111010280	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111010281	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
331111010282	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
331111010283	dimer interface [polypeptide binding]; other site
331111010284	active site
331111010285	metal binding site [ion binding]; metal-binding site
331111010286	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
331111010287	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
331111010288	active site
331111010289	catalytic tetrad [active]
331111010290	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
331111010291	putative outer membrane lipoprotein; Provisional; Region: PRK09973
331111010292	hypothetical protein; Provisional; Region: PRK01254
331111010293	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
331111010294	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
331111010295	FtsI repressor; Provisional; Region: PRK10883
331111010296	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
331111010297	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
331111010298	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
331111010299	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
331111010300	putative acyl-acceptor binding pocket; other site
331111010301	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
331111010302	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
331111010303	CAP-like domain; other site
331111010304	active site
331111010305	primary dimer interface [polypeptide binding]; other site
331111010306	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
331111010307	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
331111010308	TIGR00156 family protein; Region: TIGR00156
331111010309	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
331111010310	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111010311	active site
331111010312	phosphorylation site [posttranslational modification]
331111010313	intermolecular recognition site; other site
331111010314	dimerization interface [polypeptide binding]; other site
331111010315	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
331111010316	DNA binding site [nucleotide binding]
331111010317	sensor protein QseC; Provisional; Region: PRK10337
331111010318	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111010319	dimer interface [polypeptide binding]; other site
331111010320	phosphorylation site [posttranslational modification]
331111010321	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111010322	ATP binding site [chemical binding]; other site
331111010323	Mg2+ binding site [ion binding]; other site
331111010324	G-X-G motif; other site
331111010325	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
331111010326	Uncharacterized conserved protein [Function unknown]; Region: COG1359
331111010327	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
331111010328	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111010329	ATP binding site [chemical binding]; other site
331111010330	Mg2+ binding site [ion binding]; other site
331111010331	G-X-G motif; other site
331111010332	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
331111010333	anchoring element; other site
331111010334	dimer interface [polypeptide binding]; other site
331111010335	ATP binding site [chemical binding]; other site
331111010336	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
331111010337	active site
331111010338	metal binding site [ion binding]; metal-binding site
331111010339	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
331111010340	esterase YqiA; Provisional; Region: PRK11071
331111010341	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
331111010342	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
331111010343	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
331111010344	active site
331111010345	metal binding site [ion binding]; metal-binding site
331111010346	hexamer interface [polypeptide binding]; other site
331111010347	putative dehydrogenase; Provisional; Region: PRK11039
331111010348	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
331111010349	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
331111010350	dimer interface [polypeptide binding]; other site
331111010351	ADP-ribose binding site [chemical binding]; other site
331111010352	active site
331111010353	nudix motif; other site
331111010354	metal binding site [ion binding]; metal-binding site
331111010355	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
331111010356	hypothetical protein; Provisional; Region: PRK11653
331111010357	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
331111010358	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
331111010359	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
331111010360	putative active site [active]
331111010361	metal binding site [ion binding]; metal-binding site
331111010362	zinc transporter ZupT; Provisional; Region: PRK04201
331111010363	ZIP Zinc transporter; Region: Zip; pfam02535
331111010364	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
331111010365	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
331111010366	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
331111010367	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
331111010368	putative fimbrial protein; Provisional; Region: PRK09733
331111010369	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
331111010370	PapC N-terminal domain; Region: PapC_N; pfam13954
331111010371	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
331111010372	PapC C-terminal domain; Region: PapC_C; pfam13953
331111010373	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
331111010374	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
331111010375	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
331111010376	Fimbrial protein; Region: Fimbrial; pfam00419
331111010377	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
331111010378	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
331111010379	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
331111010380	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
331111010381	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
331111010382	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
331111010383	putative ribose interaction site [chemical binding]; other site
331111010384	putative ADP binding site [chemical binding]; other site
331111010385	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
331111010386	active site
331111010387	nucleotide binding site [chemical binding]; other site
331111010388	HIGH motif; other site
331111010389	KMSKS motif; other site
331111010390	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
331111010391	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
331111010392	metal binding triad; other site
331111010393	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
331111010394	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
331111010395	metal binding triad; other site
331111010396	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
331111010397	Uncharacterized conserved protein [Function unknown]; Region: COG3025
331111010398	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
331111010399	putative active site [active]
331111010400	putative metal binding residues [ion binding]; other site
331111010401	signature motif; other site
331111010402	putative triphosphate binding site [ion binding]; other site
331111010403	CHAD domain; Region: CHAD; pfam05235
331111010404	SH3 domain-containing protein; Provisional; Region: PRK10884
331111010405	Bacterial SH3 domain homologues; Region: SH3b; smart00287
331111010406	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
331111010407	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
331111010408	active site
331111010409	NTP binding site [chemical binding]; other site
331111010410	metal binding triad [ion binding]; metal-binding site
331111010411	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
331111010412	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
331111010413	Zn2+ binding site [ion binding]; other site
331111010414	Mg2+ binding site [ion binding]; other site
331111010415	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
331111010416	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
331111010417	homooctamer interface [polypeptide binding]; other site
331111010418	active site
331111010419	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
331111010420	transcriptional activator TtdR; Provisional; Region: PRK09801
331111010421	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111010422	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
331111010423	putative effector binding pocket; other site
331111010424	putative dimerization interface [polypeptide binding]; other site
331111010425	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
331111010426	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
331111010427	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
331111010428	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
331111010429	transmembrane helices; other site
331111010430	UGMP family protein; Validated; Region: PRK09604
331111010431	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
331111010432	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
331111010433	DNA primase; Validated; Region: dnaG; PRK05667
331111010434	CHC2 zinc finger; Region: zf-CHC2; pfam01807
331111010435	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
331111010436	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
331111010437	active site
331111010438	metal binding site [ion binding]; metal-binding site
331111010439	interdomain interaction site; other site
331111010440	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
331111010441	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
331111010442	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
331111010443	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
331111010444	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
331111010445	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
331111010446	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
331111010447	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
331111010448	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
331111010449	DNA binding residues [nucleotide binding]
331111010450	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
331111010451	active site
331111010452	SUMO-1 interface [polypeptide binding]; other site
331111010453	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
331111010454	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
331111010455	FAD binding pocket [chemical binding]; other site
331111010456	FAD binding motif [chemical binding]; other site
331111010457	phosphate binding motif [ion binding]; other site
331111010458	NAD binding pocket [chemical binding]; other site
331111010459	Predicted transcriptional regulators [Transcription]; Region: COG1695
331111010460	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
331111010461	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
331111010462	PAS fold; Region: PAS_3; pfam08447
331111010463	putative active site [active]
331111010464	heme pocket [chemical binding]; other site
331111010465	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
331111010466	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
331111010467	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
331111010468	dimer interface [polypeptide binding]; other site
331111010469	putative CheW interface [polypeptide binding]; other site
331111010470	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
331111010471	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
331111010472	inhibitor-cofactor binding pocket; inhibition site
331111010473	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111010474	catalytic residue [active]
331111010475	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
331111010476	dimer interface [polypeptide binding]; other site
331111010477	putative tRNA-binding site [nucleotide binding]; other site
331111010478	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
331111010479	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
331111010480	DNA binding site [nucleotide binding]
331111010481	domain linker motif; other site
331111010482	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
331111010483	putative dimerization interface [polypeptide binding]; other site
331111010484	putative ligand binding site [chemical binding]; other site
331111010485	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
331111010486	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
331111010487	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
331111010488	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
331111010489	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
331111010490	cryptic beta-D-galactosidase subunit beta; Reviewed; Region: ebgC; PRK10202
331111010491	inner membrane transporter YjeM; Provisional; Region: PRK15238
331111010492	alpha-glucosidase; Provisional; Region: PRK10137
331111010493	Protein of unknown function, DUF608; Region: DUF608; pfam04685
331111010494	Trehalase; Region: Trehalase; cl17346
331111010495	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
331111010496	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
331111010497	active site
331111010498	FMN binding site [chemical binding]; other site
331111010499	2,4-decadienoyl-CoA binding site; other site
331111010500	catalytic residue [active]
331111010501	4Fe-4S cluster binding site [ion binding]; other site
331111010502	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
331111010503	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111010504	non-specific DNA binding site [nucleotide binding]; other site
331111010505	salt bridge; other site
331111010506	sequence-specific DNA binding site [nucleotide binding]; other site
331111010507	Uncharacterized protein conserved in bacteria (DUF2136); Region: DUF2136; cl01912
331111010508	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
331111010509	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111010510	S-adenosylmethionine binding site [chemical binding]; other site
331111010511	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
331111010512	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
331111010513	putative active site [active]
331111010514	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
331111010515	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
331111010516	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
331111010517	serine/threonine transporter SstT; Provisional; Region: PRK13628
331111010518	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
331111010519	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
331111010520	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
331111010521	galactarate dehydratase; Region: galactar-dH20; TIGR03248
331111010522	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
331111010523	Glucuronate isomerase; Region: UxaC; pfam02614
331111010524	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
331111010525	D-galactonate transporter; Region: 2A0114; TIGR00893
331111010526	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111010527	putative substrate translocation pore; other site
331111010528	CblD like pilus biogenesis initiator; Region: CblD; cl06460
331111010529	fimbrial outer membrane usher protein TcfC; Provisional; Region: PRK15310
331111010530	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
331111010531	CS1 type fimbrial major subunit; Region: Fimbrial_CS1; pfam04449
331111010532	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
331111010533	putative fimbrial protein TcfA; Provisional; Region: PRK15308
331111010534	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
331111010535	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111010536	DNA-binding site [nucleotide binding]; DNA binding site
331111010537	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
331111010538	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
331111010539	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
331111010540	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
331111010541	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
331111010542	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
331111010543	Predicted membrane protein [Function unknown]; Region: COG5393
331111010544	YqjK-like protein; Region: YqjK; pfam13997
331111010545	Predicted membrane protein [Function unknown]; Region: COG2259
331111010546	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
331111010547	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
331111010548	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
331111010549	putative dimer interface [polypeptide binding]; other site
331111010550	N-terminal domain interface [polypeptide binding]; other site
331111010551	putative substrate binding pocket (H-site) [chemical binding]; other site
331111010552	Predicted membrane protein [Function unknown]; Region: COG3152
331111010553	Protein of unknown function (DUF805); Region: DUF805; pfam05656
331111010554	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111010555	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
331111010556	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
331111010557	dimerization interface [polypeptide binding]; other site
331111010558	Pirin-related protein [General function prediction only]; Region: COG1741
331111010559	Pirin; Region: Pirin; pfam02678
331111010560	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
331111010561	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
331111010562	serine transporter; Region: stp; TIGR00814
331111010563	L-serine dehydratase TdcG; Provisional; Region: PRK15040
331111010564	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
331111010565	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
331111010566	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
331111010567	homotrimer interaction site [polypeptide binding]; other site
331111010568	putative active site [active]
331111010569	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
331111010570	Pyruvate formate lyase 1; Region: PFL1; cd01678
331111010571	coenzyme A binding site [chemical binding]; other site
331111010572	active site
331111010573	catalytic residues [active]
331111010574	glycine loop; other site
331111010575	propionate/acetate kinase; Provisional; Region: PRK12379
331111010576	Acetokinase family; Region: Acetate_kinase; cl17229
331111010577	threonine/serine transporter TdcC; Provisional; Region: PRK13629
331111010578	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
331111010579	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
331111010580	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
331111010581	tetramer interface [polypeptide binding]; other site
331111010582	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111010583	catalytic residue [active]
331111010584	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
331111010585	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111010586	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
331111010587	putative substrate binding pocket [chemical binding]; other site
331111010588	putative dimerization interface [polypeptide binding]; other site
331111010589	DNA-binding transcriptional activator TdcR; Provisional; Region: PRK11424
331111010590	hypothetical protein; Provisional; Region: PRK09716
331111010591	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
331111010592	glycerate kinase I; Provisional; Region: PRK10342
331111010593	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
331111010594	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
331111010595	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
331111010596	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111010597	D-galactonate transporter; Region: 2A0114; TIGR00893
331111010598	putative substrate translocation pore; other site
331111010599	galactarate dehydratase; Region: galactar-dH20; TIGR03248
331111010600	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
331111010601	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
331111010602	putative regulator PrlF; Provisional; Region: PRK09974
331111010603	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
331111010604	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
331111010605	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
331111010606	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
331111010607	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
331111010608	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
331111010609	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
331111010610	active site
331111010611	phosphorylation site [posttranslational modification]
331111010612	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
331111010613	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
331111010614	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
331111010615	active pocket/dimerization site; other site
331111010616	active site
331111010617	phosphorylation site [posttranslational modification]
331111010618	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
331111010619	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
331111010620	active site
331111010621	dimer interface [polypeptide binding]; other site
331111010622	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
331111010623	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
331111010624	dimer interface [polypeptide binding]; other site
331111010625	active site
331111010626	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
331111010627	putative active site [active]
331111010628	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cd00453
331111010629	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
331111010630	active site
331111010631	intersubunit interface [polypeptide binding]; other site
331111010632	zinc binding site [ion binding]; other site
331111010633	Na+ binding site [ion binding]; other site
331111010634	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
331111010635	active site
331111010636	phosphorylation site [posttranslational modification]
331111010637	PTS system N-acetylgalactosamine-specific transporter subunit IIC; Provisional; Region: PRK09757
331111010638	PTS system N-acetylgalactosamine-specific transporter subunit IID; Provisional; Region: PRK09855
331111010639	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
331111010640	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
331111010641	active site
331111010642	trimer interface [polypeptide binding]; other site
331111010643	allosteric site; other site
331111010644	active site lid [active]
331111010645	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
331111010646	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
331111010647	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
331111010648	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
331111010649	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
331111010650	PapC N-terminal domain; Region: PapC_N; pfam13954
331111010651	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
331111010652	PapC C-terminal domain; Region: PapC_C; pfam13953
331111010653	Fimbrial protein; Region: Fimbrial; pfam00419
331111010654	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
331111010655	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
331111010656	putative SAM binding site [chemical binding]; other site
331111010657	putative homodimer interface [polypeptide binding]; other site
331111010658	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
331111010659	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
331111010660	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
331111010661	putative ligand binding site [chemical binding]; other site
331111010662	TIGR00252 family protein; Region: TIGR00252
331111010663	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
331111010664	dimer interface [polypeptide binding]; other site
331111010665	active site
331111010666	outer membrane lipoprotein; Provisional; Region: PRK11023
331111010667	BON domain; Region: BON; pfam04972
331111010668	BON domain; Region: BON; pfam04972
331111010669	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
331111010670	NADH(P)-binding; Region: NAD_binding_10; pfam13460
331111010671	NAD binding site [chemical binding]; other site
331111010672	active site
331111010673	intracellular protease, PfpI family; Region: PfpI; TIGR01382
331111010674	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
331111010675	proposed catalytic triad [active]
331111010676	conserved cys residue [active]
331111010677	hypothetical protein; Provisional; Region: PRK03467
331111010678	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
331111010679	GIY-YIG motif/motif A; other site
331111010680	putative active site [active]
331111010681	putative metal binding site [ion binding]; other site
331111010682	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
331111010683	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
331111010684	Coenzyme A binding pocket [chemical binding]; other site
331111010685	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
331111010686	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
331111010687	Peptidase family U32; Region: Peptidase_U32; pfam01136
331111010688	putative protease; Provisional; Region: PRK15447
331111010689	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
331111010690	hypothetical protein; Provisional; Region: PRK10508
331111010691	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
331111010692	tryptophan permease; Provisional; Region: PRK10483
331111010693	aromatic amino acid transport protein; Region: araaP; TIGR00837
331111010694	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
331111010695	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
331111010696	ATP binding site [chemical binding]; other site
331111010697	Mg++ binding site [ion binding]; other site
331111010698	motif III; other site
331111010699	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111010700	nucleotide binding region [chemical binding]; other site
331111010701	ATP-binding site [chemical binding]; other site
331111010702	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
331111010703	putative RNA binding site [nucleotide binding]; other site
331111010704	lipoprotein NlpI; Provisional; Region: PRK11189
331111010705	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
331111010706	binding surface
331111010707	TPR motif; other site
331111010708	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
331111010709	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
331111010710	RNase E interface [polypeptide binding]; other site
331111010711	trimer interface [polypeptide binding]; other site
331111010712	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
331111010713	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
331111010714	RNase E interface [polypeptide binding]; other site
331111010715	trimer interface [polypeptide binding]; other site
331111010716	active site
331111010717	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
331111010718	putative nucleic acid binding region [nucleotide binding]; other site
331111010719	G-X-X-G motif; other site
331111010720	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
331111010721	RNA binding site [nucleotide binding]; other site
331111010722	domain interface; other site
331111010723	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
331111010724	16S/18S rRNA binding site [nucleotide binding]; other site
331111010725	S13e-L30e interaction site [polypeptide binding]; other site
331111010726	25S rRNA binding site [nucleotide binding]; other site
331111010727	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
331111010728	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
331111010729	RNA binding site [nucleotide binding]; other site
331111010730	active site
331111010731	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
331111010732	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
331111010733	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
331111010734	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
331111010735	translation initiation factor IF-2; Region: IF-2; TIGR00487
331111010736	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
331111010737	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
331111010738	G1 box; other site
331111010739	putative GEF interaction site [polypeptide binding]; other site
331111010740	GTP/Mg2+ binding site [chemical binding]; other site
331111010741	Switch I region; other site
331111010742	G2 box; other site
331111010743	G3 box; other site
331111010744	Switch II region; other site
331111010745	G4 box; other site
331111010746	G5 box; other site
331111010747	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
331111010748	Translation-initiation factor 2; Region: IF-2; pfam11987
331111010749	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
331111010750	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
331111010751	NusA N-terminal domain; Region: NusA_N; pfam08529
331111010752	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
331111010753	RNA binding site [nucleotide binding]; other site
331111010754	homodimer interface [polypeptide binding]; other site
331111010755	NusA-like KH domain; Region: KH_5; pfam13184
331111010756	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
331111010757	G-X-X-G motif; other site
331111010758	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
331111010759	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
331111010760	ribosome maturation protein RimP; Reviewed; Region: PRK00092
331111010761	Sm and related proteins; Region: Sm_like; cl00259
331111010762	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
331111010763	putative oligomer interface [polypeptide binding]; other site
331111010764	putative RNA binding site [nucleotide binding]; other site
331111010765	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
331111010766	ANP binding site [chemical binding]; other site
331111010767	Substrate Binding Site II [chemical binding]; other site
331111010768	Substrate Binding Site I [chemical binding]; other site
331111010769	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
331111010770	Sulfatase; Region: Sulfatase; pfam00884
331111010771	Preprotein translocase SecG subunit; Region: SecG; pfam03840
331111010772	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
331111010773	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
331111010774	active site
331111010775	substrate binding site [chemical binding]; other site
331111010776	metal binding site [ion binding]; metal-binding site
331111010777	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
331111010778	dihydropteroate synthase; Region: DHPS; TIGR01496
331111010779	substrate binding pocket [chemical binding]; other site
331111010780	dimer interface [polypeptide binding]; other site
331111010781	inhibitor binding site; inhibition site
331111010782	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
331111010783	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111010784	Walker A motif; other site
331111010785	ATP binding site [chemical binding]; other site
331111010786	Walker B motif; other site
331111010787	arginine finger; other site
331111010788	Peptidase family M41; Region: Peptidase_M41; pfam01434
331111010789	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
331111010790	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111010791	S-adenosylmethionine binding site [chemical binding]; other site
331111010792	RNA-binding protein YhbY; Provisional; Region: PRK10343
331111010793	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
331111010794	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
331111010795	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
331111010796	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
331111010797	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
331111010798	GTPase CgtA; Reviewed; Region: obgE; PRK12298
331111010799	GTP1/OBG; Region: GTP1_OBG; pfam01018
331111010800	Obg GTPase; Region: Obg; cd01898
331111010801	G1 box; other site
331111010802	GTP/Mg2+ binding site [chemical binding]; other site
331111010803	Switch I region; other site
331111010804	G2 box; other site
331111010805	G3 box; other site
331111010806	Switch II region; other site
331111010807	G4 box; other site
331111010808	G5 box; other site
331111010809	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
331111010810	EamA-like transporter family; Region: EamA; pfam00892
331111010811	EamA-like transporter family; Region: EamA; pfam00892
331111010812	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
331111010813	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
331111010814	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
331111010815	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
331111010816	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
331111010817	substrate binding pocket [chemical binding]; other site
331111010818	chain length determination region; other site
331111010819	substrate-Mg2+ binding site; other site
331111010820	catalytic residues [active]
331111010821	aspartate-rich region 1; other site
331111010822	active site lid residues [active]
331111010823	aspartate-rich region 2; other site
331111010824	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
331111010825	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
331111010826	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
331111010827	hinge; other site
331111010828	active site
331111010829	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
331111010830	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
331111010831	anti sigma factor interaction site; other site
331111010832	regulatory phosphorylation site [posttranslational modification]; other site
331111010833	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
331111010834	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
331111010835	mce related protein; Region: MCE; pfam02470
331111010836	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
331111010837	conserved hypothetical integral membrane protein; Region: TIGR00056
331111010838	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
331111010839	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
331111010840	Walker A/P-loop; other site
331111010841	ATP binding site [chemical binding]; other site
331111010842	Q-loop/lid; other site
331111010843	ABC transporter signature motif; other site
331111010844	Walker B; other site
331111010845	D-loop; other site
331111010846	H-loop/switch region; other site
331111010847	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
331111010848	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
331111010849	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
331111010850	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
331111010851	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
331111010852	putative active site [active]
331111010853	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
331111010854	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
331111010855	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
331111010856	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
331111010857	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
331111010858	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
331111010859	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
331111010860	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
331111010861	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
331111010862	Walker A/P-loop; other site
331111010863	ATP binding site [chemical binding]; other site
331111010864	Q-loop/lid; other site
331111010865	ABC transporter signature motif; other site
331111010866	Walker B; other site
331111010867	D-loop; other site
331111010868	H-loop/switch region; other site
331111010869	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
331111010870	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
331111010871	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
331111010872	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
331111010873	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
331111010874	30S subunit binding site; other site
331111010875	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
331111010876	active site
331111010877	phosphorylation site [posttranslational modification]
331111010878	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
331111010879	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
331111010880	dimerization domain swap beta strand [polypeptide binding]; other site
331111010881	regulatory protein interface [polypeptide binding]; other site
331111010882	active site
331111010883	regulatory phosphorylation site [posttranslational modification]; other site
331111010884	hypothetical protein; Provisional; Region: PRK10345
331111010885	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
331111010886	Transglycosylase; Region: Transgly; cl17702
331111010887	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
331111010888	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
331111010889	conserved cys residue [active]
331111010890	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
331111010891	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
331111010892	putative active site [active]
331111010893	heme pocket [chemical binding]; other site
331111010894	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111010895	dimer interface [polypeptide binding]; other site
331111010896	phosphorylation site [posttranslational modification]
331111010897	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111010898	ATP binding site [chemical binding]; other site
331111010899	Mg2+ binding site [ion binding]; other site
331111010900	G-X-G motif; other site
331111010901	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111010902	active site
331111010903	phosphorylation site [posttranslational modification]
331111010904	intermolecular recognition site; other site
331111010905	dimerization interface [polypeptide binding]; other site
331111010906	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
331111010907	putative binding surface; other site
331111010908	active site
331111010909	radical SAM protein, TIGR01212 family; Region: TIGR01212
331111010910	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111010911	FeS/SAM binding site; other site
331111010912	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
331111010913	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
331111010914	active site
331111010915	dimer interface [polypeptide binding]; other site
331111010916	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
331111010917	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
331111010918	active site
331111010919	FMN binding site [chemical binding]; other site
331111010920	substrate binding site [chemical binding]; other site
331111010921	3Fe-4S cluster binding site [ion binding]; other site
331111010922	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
331111010923	domain interface; other site
331111010924	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
331111010925	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
331111010926	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111010927	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
331111010928	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
331111010929	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
331111010930	N-acetylmannosamine kinase; Provisional; Region: PRK05082
331111010931	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
331111010932	nucleotide binding site [chemical binding]; other site
331111010933	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
331111010934	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
331111010935	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
331111010936	putative active site cavity [active]
331111010937	putative sialic acid transporter; Provisional; Region: PRK03893
331111010938	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111010939	putative substrate translocation pore; other site
331111010940	N-acetylneuraminate lyase; Region: nanA; TIGR00683
331111010941	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
331111010942	inhibitor site; inhibition site
331111010943	active site
331111010944	dimer interface [polypeptide binding]; other site
331111010945	catalytic residue [active]
331111010946	transcriptional regulator NanR; Provisional; Region: PRK03837
331111010947	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111010948	DNA-binding site [nucleotide binding]; DNA binding site
331111010949	FCD domain; Region: FCD; pfam07729
331111010950	putative cryptic C4-dicarboxylate transporter DcuD; Provisional; Region: PRK09804
331111010951	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
331111010952	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
331111010953	stringent starvation protein A; Provisional; Region: sspA; PRK09481
331111010954	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
331111010955	C-terminal domain interface [polypeptide binding]; other site
331111010956	putative GSH binding site (G-site) [chemical binding]; other site
331111010957	dimer interface [polypeptide binding]; other site
331111010958	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
331111010959	dimer interface [polypeptide binding]; other site
331111010960	N-terminal domain interface [polypeptide binding]; other site
331111010961	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
331111010962	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
331111010963	23S rRNA interface [nucleotide binding]; other site
331111010964	L3 interface [polypeptide binding]; other site
331111010965	Predicted ATPase [General function prediction only]; Region: COG1485
331111010966	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
331111010967	hypothetical protein; Provisional; Region: PRK11677
331111010968	serine endoprotease; Provisional; Region: PRK10139
331111010969	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
331111010970	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
331111010971	protein binding site [polypeptide binding]; other site
331111010972	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
331111010973	serine endoprotease; Provisional; Region: PRK10898
331111010974	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
331111010975	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
331111010976	malate dehydrogenase; Provisional; Region: PRK05086
331111010977	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
331111010978	NAD binding site [chemical binding]; other site
331111010979	dimerization interface [polypeptide binding]; other site
331111010980	Substrate binding site [chemical binding]; other site
331111010981	arginine repressor; Provisional; Region: PRK05066
331111010982	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
331111010983	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
331111010984	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
331111010985	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
331111010986	RNAase interaction site [polypeptide binding]; other site
331111010987	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
331111010988	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
331111010989	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
331111010990	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
331111010991	HlyD family secretion protein; Region: HlyD_3; pfam13437
331111010992	efflux system membrane protein; Provisional; Region: PRK11594
331111010993	transcriptional regulator; Provisional; Region: PRK10632
331111010994	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111010995	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
331111010996	putative effector binding pocket; other site
331111010997	dimerization interface [polypeptide binding]; other site
331111010998	protease TldD; Provisional; Region: tldD; PRK10735
331111010999	hypothetical protein; Provisional; Region: PRK10899
331111011000	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
331111011001	ribonuclease G; Provisional; Region: PRK11712
331111011002	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
331111011003	homodimer interface [polypeptide binding]; other site
331111011004	oligonucleotide binding site [chemical binding]; other site
331111011005	Maf-like protein; Region: Maf; pfam02545
331111011006	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
331111011007	active site
331111011008	dimer interface [polypeptide binding]; other site
331111011009	rod shape-determining protein MreD; Provisional; Region: PRK11060
331111011010	rod shape-determining protein MreC; Region: mreC; TIGR00219
331111011011	rod shape-determining protein MreC; Region: MreC; pfam04085
331111011012	rod shape-determining protein MreB; Provisional; Region: PRK13927
331111011013	MreB and similar proteins; Region: MreB_like; cd10225
331111011014	nucleotide binding site [chemical binding]; other site
331111011015	Mg binding site [ion binding]; other site
331111011016	putative protofilament interaction site [polypeptide binding]; other site
331111011017	RodZ interaction site [polypeptide binding]; other site
331111011018	regulatory protein CsrD; Provisional; Region: PRK11059
331111011019	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111011020	metal binding site [ion binding]; metal-binding site
331111011021	active site
331111011022	I-site; other site
331111011023	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
331111011024	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
331111011025	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
331111011026	NADP binding site [chemical binding]; other site
331111011027	dimer interface [polypeptide binding]; other site
331111011028	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
331111011029	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
331111011030	carboxyltransferase (CT) interaction site; other site
331111011031	biotinylation site [posttranslational modification]; other site
331111011032	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
331111011033	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
331111011034	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
331111011035	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
331111011036	hypothetical protein; Provisional; Region: PRK10633
331111011037	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
331111011038	Na binding site [ion binding]; other site
331111011039	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
331111011040	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
331111011041	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
331111011042	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
331111011043	FMN binding site [chemical binding]; other site
331111011044	active site
331111011045	catalytic residues [active]
331111011046	substrate binding site [chemical binding]; other site
331111011047	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
331111011048	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
331111011049	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
331111011050	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111011051	DNA methylase; Region: N6_N4_Mtase; pfam01555
331111011052	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
331111011053	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
331111011054	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
331111011055	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
331111011056	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
331111011057	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
331111011058	HlyD family secretion protein; Region: HlyD_3; pfam13437
331111011059	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
331111011060	Protein export membrane protein; Region: SecD_SecF; cl14618
331111011061	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
331111011062	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
331111011063	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111011064	substrate binding pocket [chemical binding]; other site
331111011065	membrane-bound complex binding site; other site
331111011066	hinge residues; other site
331111011067	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
331111011068	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111011069	conserved gate region; other site
331111011070	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111011071	dimer interface [polypeptide binding]; other site
331111011072	conserved gate region; other site
331111011073	putative PBP binding loops; other site
331111011074	ABC-ATPase subunit interface; other site
331111011075	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
331111011076	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111011077	dimer interface [polypeptide binding]; other site
331111011078	conserved gate region; other site
331111011079	putative PBP binding loops; other site
331111011080	ABC-ATPase subunit interface; other site
331111011081	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
331111011082	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
331111011083	Walker A/P-loop; other site
331111011084	ATP binding site [chemical binding]; other site
331111011085	Q-loop/lid; other site
331111011086	ABC transporter signature motif; other site
331111011087	Walker B; other site
331111011088	D-loop; other site
331111011089	H-loop/switch region; other site
331111011090	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
331111011091	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
331111011092	trimer interface [polypeptide binding]; other site
331111011093	putative metal binding site [ion binding]; other site
331111011094	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
331111011095	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
331111011096	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
331111011097	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
331111011098	shikimate binding site; other site
331111011099	NAD(P) binding site [chemical binding]; other site
331111011100	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
331111011101	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
331111011102	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
331111011103	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
331111011104	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
331111011105	hypothetical protein; Validated; Region: PRK03430
331111011106	hypothetical protein; Provisional; Region: PRK10736
331111011107	DNA protecting protein DprA; Region: dprA; TIGR00732
331111011108	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
331111011109	active site
331111011110	catalytic residues [active]
331111011111	metal binding site [ion binding]; metal-binding site
331111011112	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
331111011113	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
331111011114	putative active site [active]
331111011115	substrate binding site [chemical binding]; other site
331111011116	putative cosubstrate binding site; other site
331111011117	catalytic site [active]
331111011118	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
331111011119	substrate binding site [chemical binding]; other site
331111011120	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
331111011121	putative RNA binding site [nucleotide binding]; other site
331111011122	16S rRNA methyltransferase B; Provisional; Region: PRK10901
331111011123	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111011124	S-adenosylmethionine binding site [chemical binding]; other site
331111011125	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
331111011126	TrkA-N domain; Region: TrkA_N; pfam02254
331111011127	TrkA-C domain; Region: TrkA_C; pfam02080
331111011128	TrkA-N domain; Region: TrkA_N; pfam02254
331111011129	TrkA-C domain; Region: TrkA_C; pfam02080
331111011130	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
331111011131	Large-conductance mechanosensitive channel, MscL; Region: MscL; pfam01741
331111011132	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
331111011133	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
331111011134	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
331111011135	DNA binding residues [nucleotide binding]
331111011136	dimer interface [polypeptide binding]; other site
331111011137	metal binding site [ion binding]; metal-binding site
331111011138	hypothetical protein; Provisional; Region: PRK10203
331111011139	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
331111011140	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
331111011141	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
331111011142	alphaNTD homodimer interface [polypeptide binding]; other site
331111011143	alphaNTD - beta interaction site [polypeptide binding]; other site
331111011144	alphaNTD - beta' interaction site [polypeptide binding]; other site
331111011145	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
331111011146	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
331111011147	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
331111011148	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
331111011149	RNA binding surface [nucleotide binding]; other site
331111011150	30S ribosomal protein S11; Validated; Region: PRK05309
331111011151	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
331111011152	30S ribosomal protein S13; Region: bact_S13; TIGR03631
331111011153	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
331111011154	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
331111011155	SecY translocase; Region: SecY; pfam00344
331111011156	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
331111011157	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
331111011158	23S rRNA binding site [nucleotide binding]; other site
331111011159	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
331111011160	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
331111011161	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
331111011162	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
331111011163	23S rRNA interface [nucleotide binding]; other site
331111011164	5S rRNA interface [nucleotide binding]; other site
331111011165	L27 interface [polypeptide binding]; other site
331111011166	L5 interface [polypeptide binding]; other site
331111011167	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
331111011168	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
331111011169	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
331111011170	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
331111011171	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
331111011172	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
331111011173	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
331111011174	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
331111011175	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
331111011176	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
331111011177	RNA binding site [nucleotide binding]; other site
331111011178	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
331111011179	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
331111011180	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
331111011181	23S rRNA interface [nucleotide binding]; other site
331111011182	putative translocon interaction site; other site
331111011183	signal recognition particle (SRP54) interaction site; other site
331111011184	L23 interface [polypeptide binding]; other site
331111011185	trigger factor interaction site; other site
331111011186	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
331111011187	23S rRNA interface [nucleotide binding]; other site
331111011188	5S rRNA interface [nucleotide binding]; other site
331111011189	putative antibiotic binding site [chemical binding]; other site
331111011190	L25 interface [polypeptide binding]; other site
331111011191	L27 interface [polypeptide binding]; other site
331111011192	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
331111011193	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
331111011194	G-X-X-G motif; other site
331111011195	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
331111011196	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
331111011197	protein-rRNA interface [nucleotide binding]; other site
331111011198	putative translocon binding site; other site
331111011199	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
331111011200	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
331111011201	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
331111011202	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
331111011203	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
331111011204	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
331111011205	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
331111011206	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
331111011207	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
331111011208	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
331111011209	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
331111011210	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
331111011211	heme binding site [chemical binding]; other site
331111011212	ferroxidase pore; other site
331111011213	ferroxidase diiron center [ion binding]; other site
331111011214	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
331111011215	elongation factor Tu; Reviewed; Region: PRK00049
331111011216	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
331111011217	G1 box; other site
331111011218	GEF interaction site [polypeptide binding]; other site
331111011219	GTP/Mg2+ binding site [chemical binding]; other site
331111011220	Switch I region; other site
331111011221	G2 box; other site
331111011222	G3 box; other site
331111011223	Switch II region; other site
331111011224	G4 box; other site
331111011225	G5 box; other site
331111011226	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
331111011227	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
331111011228	Antibiotic Binding Site [chemical binding]; other site
331111011229	elongation factor G; Reviewed; Region: PRK00007
331111011230	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
331111011231	G1 box; other site
331111011232	putative GEF interaction site [polypeptide binding]; other site
331111011233	GTP/Mg2+ binding site [chemical binding]; other site
331111011234	Switch I region; other site
331111011235	G2 box; other site
331111011236	G3 box; other site
331111011237	Switch II region; other site
331111011238	G4 box; other site
331111011239	G5 box; other site
331111011240	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
331111011241	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
331111011242	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
331111011243	30S ribosomal protein S7; Validated; Region: PRK05302
331111011244	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
331111011245	S17 interaction site [polypeptide binding]; other site
331111011246	S8 interaction site; other site
331111011247	16S rRNA interaction site [nucleotide binding]; other site
331111011248	streptomycin interaction site [chemical binding]; other site
331111011249	23S rRNA interaction site [nucleotide binding]; other site
331111011250	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
331111011251	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
331111011252	sulfur relay protein TusC; Validated; Region: PRK00211
331111011253	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
331111011254	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
331111011255	YheO-like PAS domain; Region: PAS_6; pfam08348
331111011256	HTH domain; Region: HTH_22; pfam13309
331111011257	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
331111011258	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
331111011259	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
331111011260	phi X174 lysis protein; Provisional; Region: PRK02793
331111011261	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
331111011262	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
331111011263	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
331111011264	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
331111011265	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
331111011266	TrkA-N domain; Region: TrkA_N; pfam02254
331111011267	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
331111011268	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
331111011269	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111011270	Walker A/P-loop; other site
331111011271	ATP binding site [chemical binding]; other site
331111011272	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
331111011273	ABC transporter signature motif; other site
331111011274	Walker B; other site
331111011275	D-loop; other site
331111011276	ABC transporter; Region: ABC_tran_2; pfam12848
331111011277	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
331111011278	putative hydrolase; Provisional; Region: PRK10985
331111011279	hypothetical protein; Provisional; Region: PRK04966
331111011280	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
331111011281	active site
331111011282	hypothetical protein; Provisional; Region: PRK10738
331111011283	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
331111011284	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
331111011285	ligand binding site [chemical binding]; other site
331111011286	flexible hinge region; other site
331111011287	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
331111011288	putative switch regulator; other site
331111011289	non-specific DNA interactions [nucleotide binding]; other site
331111011290	DNA binding site [nucleotide binding]
331111011291	sequence specific DNA binding site [nucleotide binding]; other site
331111011292	putative cAMP binding site [chemical binding]; other site
331111011293	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
331111011294	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
331111011295	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
331111011296	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
331111011297	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
331111011298	inhibitor-cofactor binding pocket; inhibition site
331111011299	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111011300	catalytic residue [active]
331111011301	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
331111011302	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
331111011303	glutamine binding [chemical binding]; other site
331111011304	catalytic triad [active]
331111011305	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
331111011306	cell filamentation protein Fic; Provisional; Region: PRK10347
331111011307	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
331111011308	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
331111011309	substrate binding site [chemical binding]; other site
331111011310	putative transporter; Provisional; Region: PRK03699
331111011311	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111011312	putative substrate translocation pore; other site
331111011313	nitrite reductase subunit NirD; Provisional; Region: PRK14989
331111011314	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111011315	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
331111011316	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
331111011317	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
331111011318	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
331111011319	nitrite transporter NirC; Provisional; Region: PRK11562
331111011320	siroheme synthase; Provisional; Region: cysG; PRK10637
331111011321	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
331111011322	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
331111011323	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
331111011324	active site
331111011325	SAM binding site [chemical binding]; other site
331111011326	homodimer interface [polypeptide binding]; other site
331111011327	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
331111011328	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
331111011329	hypothetical protein; Provisional; Region: PHA02764
331111011330	fructoselysine-6-P-deglycase; Provisional; Region: frlB; PRK11382
331111011331	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
331111011332	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
331111011333	dimer interface [polypeptide binding]; other site
331111011334	active site
331111011335	fructoselysine 3-epimerase; Provisional; Region: PRK09856
331111011336	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
331111011337	AP (apurinic/apyrimidinic) site pocket; other site
331111011338	DNA interaction; other site
331111011339	Metal-binding active site; metal-binding site
331111011340	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
331111011341	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
331111011342	substrate binding site [chemical binding]; other site
331111011343	ATP binding site [chemical binding]; other site
331111011344	DNA-binding transcriptional regulator FrlR; Provisional; Region: PRK11402
331111011345	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111011346	DNA-binding site [nucleotide binding]; DNA binding site
331111011347	UTRA domain; Region: UTRA; pfam07702
331111011348	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
331111011349	DNA topoisomerase III, bacteria and conjugative plasmid; Region: topB; TIGR01056
331111011350	Protein of unknown function; Region: YhfT; pfam10797
331111011351	Protein of unknown function DUF2620; Region: DUF2620; pfam10941
331111011352	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
331111011353	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
331111011354	active site
331111011355	substrate binding pocket [chemical binding]; other site
331111011356	homodimer interaction site [polypeptide binding]; other site
331111011357	putative mutase; Provisional; Region: PRK12383
331111011358	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; COG1015
331111011359	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme yhfX; Region: PLPDE_III_yhfX_like; cd06811
331111011360	dimer interface [polypeptide binding]; other site
331111011361	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
331111011362	active site
331111011363	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
331111011364	substrate binding site [chemical binding]; other site
331111011365	catalytic residue [active]
331111011366	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
331111011367	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
331111011368	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
331111011369	active site
331111011370	HIGH motif; other site
331111011371	dimer interface [polypeptide binding]; other site
331111011372	KMSKS motif; other site
331111011373	phosphoglycolate phosphatase; Provisional; Region: PRK13222
331111011374	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
331111011375	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111011376	motif II; other site
331111011377	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
331111011378	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
331111011379	substrate binding site [chemical binding]; other site
331111011380	hexamer interface [polypeptide binding]; other site
331111011381	metal binding site [ion binding]; metal-binding site
331111011382	DNA adenine methylase; Provisional; Region: PRK10904
331111011383	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
331111011384	cell division protein DamX; Validated; Region: PRK10905
331111011385	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
331111011386	active site
331111011387	dimer interface [polypeptide binding]; other site
331111011388	metal binding site [ion binding]; metal-binding site
331111011389	shikimate kinase; Reviewed; Region: aroK; PRK00131
331111011390	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
331111011391	ADP binding site [chemical binding]; other site
331111011392	magnesium binding site [ion binding]; other site
331111011393	putative shikimate binding site; other site
331111011394	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
331111011395	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
331111011396	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
331111011397	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
331111011398	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
331111011399	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
331111011400	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
331111011401	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
331111011402	Transglycosylase; Region: Transgly; pfam00912
331111011403	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
331111011404	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
331111011405	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
331111011406	ADP-ribose binding site [chemical binding]; other site
331111011407	dimer interface [polypeptide binding]; other site
331111011408	active site
331111011409	nudix motif; other site
331111011410	metal binding site [ion binding]; metal-binding site
331111011411	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
331111011412	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
331111011413	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111011414	motif II; other site
331111011415	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
331111011416	RNA binding surface [nucleotide binding]; other site
331111011417	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
331111011418	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
331111011419	dimerization interface [polypeptide binding]; other site
331111011420	domain crossover interface; other site
331111011421	redox-dependent activation switch; other site
331111011422	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
331111011423	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
331111011424	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
331111011425	active site
331111011426	substrate-binding site [chemical binding]; other site
331111011427	metal-binding site [ion binding]
331111011428	ATP binding site [chemical binding]; other site
331111011429	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
331111011430	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
331111011431	dimerization interface [polypeptide binding]; other site
331111011432	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111011433	dimer interface [polypeptide binding]; other site
331111011434	phosphorylation site [posttranslational modification]
331111011435	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111011436	ATP binding site [chemical binding]; other site
331111011437	G-X-G motif; other site
331111011438	osmolarity response regulator; Provisional; Region: ompR; PRK09468
331111011439	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111011440	active site
331111011441	phosphorylation site [posttranslational modification]
331111011442	intermolecular recognition site; other site
331111011443	dimerization interface [polypeptide binding]; other site
331111011444	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
331111011445	DNA binding site [nucleotide binding]
331111011446	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
331111011447	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
331111011448	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
331111011449	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
331111011450	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
331111011451	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
331111011452	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
331111011453	RNA binding site [nucleotide binding]; other site
331111011454	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
331111011455	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
331111011456	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
331111011457	G1 box; other site
331111011458	GTP/Mg2+ binding site [chemical binding]; other site
331111011459	Switch I region; other site
331111011460	G2 box; other site
331111011461	G3 box; other site
331111011462	Switch II region; other site
331111011463	G4 box; other site
331111011464	G5 box; other site
331111011465	Nucleoside recognition; Region: Gate; pfam07670
331111011466	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
331111011467	Nucleoside recognition; Region: Gate; pfam07670
331111011468	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
331111011469	putative transposase; Provisional; Region: PRK09857
331111011470	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
331111011471	carboxylesterase BioH; Provisional; Region: PRK10349
331111011472	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
331111011473	DNA utilization protein GntX; Provisional; Region: PRK11595
331111011474	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
331111011475	active site
331111011476	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
331111011477	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
331111011478	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
331111011479	high-affinity gluconate transporter; Provisional; Region: PRK14984
331111011480	gluconate transporter; Region: gntP; TIGR00791
331111011481	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
331111011482	4-alpha-glucanotransferase; Region: malQ; TIGR00217
331111011483	maltodextrin phosphorylase; Provisional; Region: PRK14985
331111011484	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
331111011485	homodimer interface [polypeptide binding]; other site
331111011486	active site pocket [active]
331111011487	transcriptional regulator MalT; Provisional; Region: PRK04841
331111011488	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111011489	DNA binding residues [nucleotide binding]
331111011490	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
331111011491	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
331111011492	putative active site [active]
331111011493	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
331111011494	hypothetical protein; Reviewed; Region: PRK09588
331111011495	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
331111011496	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
331111011497	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111011498	Walker A motif; other site
331111011499	ATP binding site [chemical binding]; other site
331111011500	Walker B motif; other site
331111011501	arginine finger; other site
331111011502	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
331111011503	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
331111011504	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
331111011505	intramembrane serine protease GlpG; Provisional; Region: PRK10907
331111011506	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
331111011507	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
331111011508	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
331111011509	active site residue [active]
331111011510	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
331111011511	hypothetical protein; Provisional; Region: PRK09781; cl08057
331111011512	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
331111011513	glycogen phosphorylase; Provisional; Region: PRK14986
331111011514	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
331111011515	homodimer interface [polypeptide binding]; other site
331111011516	active site pocket [active]
331111011517	glycogen synthase; Provisional; Region: glgA; PRK00654
331111011518	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
331111011519	ADP-binding pocket [chemical binding]; other site
331111011520	homodimer interface [polypeptide binding]; other site
331111011521	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
331111011522	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
331111011523	ligand binding site; other site
331111011524	oligomer interface; other site
331111011525	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
331111011526	sulfate 1 binding site; other site
331111011527	glycogen debranching enzyme; Provisional; Region: PRK03705
331111011528	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
331111011529	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
331111011530	active site
331111011531	catalytic site [active]
331111011532	glycogen branching enzyme; Provisional; Region: PRK05402
331111011533	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
331111011534	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
331111011535	active site
331111011536	catalytic site [active]
331111011537	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
331111011538	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
331111011539	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
331111011540	putative antibiotic transporter; Provisional; Region: PRK10739
331111011541	low affinity gluconate transporter; Provisional; Region: PRK10472
331111011542	gluconate transporter; Region: gntP; TIGR00791
331111011543	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
331111011544	ATP-binding site [chemical binding]; other site
331111011545	Gluconate-6-phosphate binding site [chemical binding]; other site
331111011546	Shikimate kinase; Region: SKI; pfam01202
331111011547	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
331111011548	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
331111011549	DNA binding site [nucleotide binding]
331111011550	domain linker motif; other site
331111011551	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
331111011552	putative ligand binding site [chemical binding]; other site
331111011553	putative dimerization interface [polypeptide binding]; other site
331111011554	Pirin-related protein [General function prediction only]; Region: COG1741
331111011555	Pirin; Region: Pirin; pfam02678
331111011556	putative oxidoreductase; Provisional; Region: PRK10206
331111011557	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
331111011558	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
331111011559	putative acetyltransferase YhhY; Provisional; Region: PRK10140
331111011560	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
331111011561	Coenzyme A binding pocket [chemical binding]; other site
331111011562	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
331111011563	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
331111011564	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
331111011565	hypothetical protein; Provisional; Region: PRK10350
331111011566	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
331111011567	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
331111011568	putative active site [active]
331111011569	catalytic site [active]
331111011570	putative metal binding site [ion binding]; other site
331111011571	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
331111011572	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
331111011573	Walker A/P-loop; other site
331111011574	ATP binding site [chemical binding]; other site
331111011575	Q-loop/lid; other site
331111011576	ABC transporter signature motif; other site
331111011577	Walker B; other site
331111011578	D-loop; other site
331111011579	H-loop/switch region; other site
331111011580	TOBE domain; Region: TOBE_2; pfam08402
331111011581	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
331111011582	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111011583	dimer interface [polypeptide binding]; other site
331111011584	conserved gate region; other site
331111011585	putative PBP binding loops; other site
331111011586	ABC-ATPase subunit interface; other site
331111011587	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
331111011588	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111011589	dimer interface [polypeptide binding]; other site
331111011590	conserved gate region; other site
331111011591	putative PBP binding loops; other site
331111011592	ABC-ATPase subunit interface; other site
331111011593	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
331111011594	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
331111011595	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
331111011596	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
331111011597	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
331111011598	Walker A/P-loop; other site
331111011599	ATP binding site [chemical binding]; other site
331111011600	Q-loop/lid; other site
331111011601	ABC transporter signature motif; other site
331111011602	Walker B; other site
331111011603	D-loop; other site
331111011604	H-loop/switch region; other site
331111011605	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
331111011606	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
331111011607	Walker A/P-loop; other site
331111011608	ATP binding site [chemical binding]; other site
331111011609	Q-loop/lid; other site
331111011610	ABC transporter signature motif; other site
331111011611	Walker B; other site
331111011612	D-loop; other site
331111011613	H-loop/switch region; other site
331111011614	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
331111011615	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
331111011616	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
331111011617	TM-ABC transporter signature motif; other site
331111011618	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
331111011619	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
331111011620	TM-ABC transporter signature motif; other site
331111011621	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
331111011622	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
331111011623	dimerization interface [polypeptide binding]; other site
331111011624	ligand binding site [chemical binding]; other site
331111011625	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
331111011626	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
331111011627	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
331111011628	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
331111011629	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
331111011630	dimerization interface [polypeptide binding]; other site
331111011631	ligand binding site [chemical binding]; other site
331111011632	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
331111011633	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
331111011634	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
331111011635	DNA binding residues [nucleotide binding]
331111011636	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
331111011637	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
331111011638	cell division protein FtsE; Provisional; Region: PRK10908
331111011639	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111011640	Walker A/P-loop; other site
331111011641	ATP binding site [chemical binding]; other site
331111011642	Q-loop/lid; other site
331111011643	ABC transporter signature motif; other site
331111011644	Walker B; other site
331111011645	D-loop; other site
331111011646	H-loop/switch region; other site
331111011647	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
331111011648	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
331111011649	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
331111011650	P loop; other site
331111011651	GTP binding site [chemical binding]; other site
331111011652	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
331111011653	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111011654	S-adenosylmethionine binding site [chemical binding]; other site
331111011655	hypothetical protein; Provisional; Region: PRK10910
331111011656	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
331111011657	Predicted membrane protein [Function unknown]; Region: COG3714
331111011658	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
331111011659	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
331111011660	metal-binding site [ion binding]
331111011661	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
331111011662	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
331111011663	CPxP  motif; other site
331111011664	hypothetical protein; Provisional; Region: PRK11212
331111011665	hypothetical protein; Provisional; Region: PRK11615
331111011666	major facilitator superfamily transporter; Provisional; Region: PRK05122
331111011667	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111011668	putative substrate translocation pore; other site
331111011669	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
331111011670	Domain of unknown function DUF20; Region: UPF0118; pfam01594
331111011671	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
331111011672	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
331111011673	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
331111011674	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
331111011675	substrate binding site [chemical binding]; other site
331111011676	nickel transporter permease NikB; Provisional; Region: PRK10352
331111011677	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111011678	dimer interface [polypeptide binding]; other site
331111011679	conserved gate region; other site
331111011680	putative PBP binding loops; other site
331111011681	ABC-ATPase subunit interface; other site
331111011682	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
331111011683	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111011684	dimer interface [polypeptide binding]; other site
331111011685	conserved gate region; other site
331111011686	putative PBP binding loops; other site
331111011687	ABC-ATPase subunit interface; other site
331111011688	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
331111011689	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
331111011690	Walker A/P-loop; other site
331111011691	ATP binding site [chemical binding]; other site
331111011692	Q-loop/lid; other site
331111011693	ABC transporter signature motif; other site
331111011694	Walker B; other site
331111011695	D-loop; other site
331111011696	H-loop/switch region; other site
331111011697	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
331111011698	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
331111011699	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
331111011700	Walker A/P-loop; other site
331111011701	ATP binding site [chemical binding]; other site
331111011702	Q-loop/lid; other site
331111011703	ABC transporter signature motif; other site
331111011704	Walker B; other site
331111011705	D-loop; other site
331111011706	H-loop/switch region; other site
331111011707	nickel responsive regulator; Provisional; Region: PRK02967
331111011708	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
331111011709	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
331111011710	HicB family; Region: HicB; pfam05534
331111011711	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
331111011712	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
331111011713	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
331111011714	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
331111011715	Walker A/P-loop; other site
331111011716	ATP binding site [chemical binding]; other site
331111011717	Q-loop/lid; other site
331111011718	ABC transporter signature motif; other site
331111011719	Walker B; other site
331111011720	D-loop; other site
331111011721	H-loop/switch region; other site
331111011722	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
331111011723	Walker A/P-loop; other site
331111011724	ATP binding site [chemical binding]; other site
331111011725	Q-loop/lid; other site
331111011726	ABC transporter signature motif; other site
331111011727	Walker B; other site
331111011728	D-loop; other site
331111011729	H-loop/switch region; other site
331111011730	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
331111011731	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
331111011732	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
331111011733	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
331111011734	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
331111011735	Protein of unknown function (DUF2776); Region: DUF2776; pfam10951
331111011736	Predicted flavoproteins [General function prediction only]; Region: COG2081
331111011737	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
331111011738	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
331111011739	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
331111011740	universal stress protein UspB; Provisional; Region: PRK04960
331111011741	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
331111011742	Ligand Binding Site [chemical binding]; other site
331111011743	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
331111011744	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111011745	putative substrate translocation pore; other site
331111011746	POT family; Region: PTR2; pfam00854
331111011747	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111011748	S-adenosylmethionine binding site [chemical binding]; other site
331111011749	oligopeptidase A; Provisional; Region: PRK10911
331111011750	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
331111011751	active site
331111011752	Zn binding site [ion binding]; other site
331111011753	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
331111011754	glutathione reductase; Validated; Region: PRK06116
331111011755	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
331111011756	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111011757	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
331111011758	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
331111011759	dimerization interface [polypeptide binding]; other site
331111011760	putative DNA binding site [nucleotide binding]; other site
331111011761	putative Zn2+ binding site [ion binding]; other site
331111011762	arsenical pump membrane protein; Provisional; Region: PRK15445
331111011763	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
331111011764	transmembrane helices; other site
331111011765	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
331111011766	ArsC family; Region: ArsC; pfam03960
331111011767	catalytic residues [active]
331111011768	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
331111011769	dimerization interface [polypeptide binding]; other site
331111011770	putative DNA binding site [nucleotide binding]; other site
331111011771	putative Zn2+ binding site [ion binding]; other site
331111011772	Predicted permeases [General function prediction only]; Region: COG0701
331111011773	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
331111011774	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
331111011775	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111011776	DNA binding residues [nucleotide binding]
331111011777	dimerization interface [polypeptide binding]; other site
331111011778	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
331111011779	MgtC family; Region: MgtC; pfam02308
331111011780	acid-resistance protein; Provisional; Region: hdeB; PRK11566
331111011781	acid-resistance protein; Provisional; Region: PRK10208
331111011782	acid-resistance membrane protein; Provisional; Region: PRK10209
331111011783	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
331111011784	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
331111011785	pyruvate kinase; Provisional; Region: PRK05826
331111011786	multidrug efflux system protein MdtE; Provisional; Region: PRK09859
331111011787	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
331111011788	HlyD family secretion protein; Region: HlyD_3; pfam13437
331111011789	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
331111011790	Protein export membrane protein; Region: SecD_SecF; cl14618
331111011791	transcriptional regulator YdeO; Provisional; Region: PRK09940
331111011792	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111011793	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
331111011794	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111011795	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
331111011796	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111011797	catalytic residue [active]
331111011798	trehalase; Provisional; Region: treF; PRK13270
331111011799	Trehalase; Region: Trehalase; pfam01204
331111011800	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
331111011801	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111011802	DNA binding residues [nucleotide binding]
331111011803	dimerization interface [polypeptide binding]; other site
331111011804	Transcriptional regulator [Transcription]; Region: LysR; COG0583
331111011805	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111011806	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
331111011807	putative effector binding pocket; other site
331111011808	putative dimerization interface [polypeptide binding]; other site
331111011809	inner membrane protein YhjD; Region: TIGR00766
331111011810	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111011811	metabolite-proton symporter; Region: 2A0106; TIGR00883
331111011812	putative substrate translocation pore; other site
331111011813	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
331111011814	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
331111011815	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
331111011816	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
331111011817	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
331111011818	substrate binding site [chemical binding]; other site
331111011819	ATP binding site [chemical binding]; other site
331111011820	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
331111011821	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
331111011822	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
331111011823	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
331111011824	putative diguanylate cyclase; Provisional; Region: PRK13561
331111011825	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
331111011826	metal binding site [ion binding]; metal-binding site
331111011827	active site
331111011828	I-site; other site
331111011829	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
331111011830	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
331111011831	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
331111011832	binding surface
331111011833	TPR motif; other site
331111011834	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
331111011835	binding surface
331111011836	TPR motif; other site
331111011837	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
331111011838	endo-1,4-D-glucanase; Provisional; Region: PRK11097
331111011839	cellulose synthase regulator protein; Provisional; Region: PRK11114
331111011840	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
331111011841	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
331111011842	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
331111011843	DXD motif; other site
331111011844	PilZ domain; Region: PilZ; pfam07238
331111011845	cell division protein; Provisional; Region: PRK10037
331111011846	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
331111011847	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
331111011848	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
331111011849	celllulose biosynthesis operon protein BcsF/YhjT; Region: cellullose_BcsF; TIGR03493
331111011850	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
331111011851	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
331111011852	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
331111011853	serine transporter; Region: stp; TIGR00814
331111011854	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
331111011855	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
331111011856	Walker A/P-loop; other site
331111011857	ATP binding site [chemical binding]; other site
331111011858	Q-loop/lid; other site
331111011859	ABC transporter signature motif; other site
331111011860	Walker B; other site
331111011861	D-loop; other site
331111011862	H-loop/switch region; other site
331111011863	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
331111011864	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
331111011865	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
331111011866	Walker A/P-loop; other site
331111011867	ATP binding site [chemical binding]; other site
331111011868	Q-loop/lid; other site
331111011869	ABC transporter signature motif; other site
331111011870	Walker B; other site
331111011871	D-loop; other site
331111011872	H-loop/switch region; other site
331111011873	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
331111011874	dipeptide transporter; Provisional; Region: PRK10913
331111011875	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
331111011876	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111011877	dimer interface [polypeptide binding]; other site
331111011878	conserved gate region; other site
331111011879	putative PBP binding loops; other site
331111011880	ABC-ATPase subunit interface; other site
331111011881	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
331111011882	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111011883	dimer interface [polypeptide binding]; other site
331111011884	conserved gate region; other site
331111011885	putative PBP binding loops; other site
331111011886	ABC-ATPase subunit interface; other site
331111011887	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
331111011888	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
331111011889	peptide binding site [polypeptide binding]; other site
331111011890	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
331111011891	Transposase; Region: DEDD_Tnp_IS110; pfam01548
331111011892	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
331111011893	phosphoethanolamine transferase; Provisional; Region: PRK11560
331111011894	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
331111011895	Sulfatase; Region: Sulfatase; pfam00884
331111011896	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
331111011897	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111011898	putative substrate translocation pore; other site
331111011899	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
331111011900	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
331111011901	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
331111011902	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
331111011903	Coenzyme A binding pocket [chemical binding]; other site
331111011904	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
331111011905	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
331111011906	molybdopterin cofactor binding site [chemical binding]; other site
331111011907	substrate binding site [chemical binding]; other site
331111011908	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
331111011909	molybdopterin cofactor binding site; other site
331111011910	putative outer membrane lipoprotein; Provisional; Region: PRK10510
331111011911	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
331111011912	ligand binding site [chemical binding]; other site
331111011913	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
331111011914	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
331111011915	dimerization interface [polypeptide binding]; other site
331111011916	ligand binding site [chemical binding]; other site
331111011917	NADP binding site [chemical binding]; other site
331111011918	catalytic site [active]
331111011919	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
331111011920	Predicted transcriptional regulator [Transcription]; Region: COG2944
331111011921	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111011922	non-specific DNA binding site [nucleotide binding]; other site
331111011923	salt bridge; other site
331111011924	sequence-specific DNA binding site [nucleotide binding]; other site
331111011925	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
331111011926	DNA-binding site [nucleotide binding]; DNA binding site
331111011927	RNA-binding motif; other site
331111011928	small toxic polypeptide; Provisional; Region: PRK09759
331111011929	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
331111011930	DALR anticodon binding domain; Region: DALR_1; pfam05746
331111011931	anticodon binding site; other site
331111011932	tRNA binding surface [nucleotide binding]; other site
331111011933	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
331111011934	dimer interface [polypeptide binding]; other site
331111011935	motif 1; other site
331111011936	active site
331111011937	motif 2; other site
331111011938	motif 3; other site
331111011939	YsaB-like lipoprotein; Region: YsaB; pfam13983
331111011940	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
331111011941	Acyltransferase family; Region: Acyl_transf_3; pfam01757
331111011942	hypothetical protein; Provisional; Region: PRK11383
331111011943	yiaA/B two helix domain; Region: YiaAB; pfam05360
331111011944	yiaA/B two helix domain; Region: YiaAB; pfam05360
331111011945	hypothetical protein; Provisional; Region: PRK11403
331111011946	yiaA/B two helix domain; Region: YiaAB; pfam05360
331111011947	xylulokinase; Provisional; Region: PRK15027
331111011948	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
331111011949	N- and C-terminal domain interface [polypeptide binding]; other site
331111011950	active site
331111011951	MgATP binding site [chemical binding]; other site
331111011952	catalytic site [active]
331111011953	metal binding site [ion binding]; metal-binding site
331111011954	xylulose binding site [chemical binding]; other site
331111011955	homodimer interface [polypeptide binding]; other site
331111011956	xylose isomerase; Provisional; Region: PRK05474
331111011957	xylose isomerase; Region: xylose_isom_A; TIGR02630
331111011958	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
331111011959	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
331111011960	putative ligand binding site [chemical binding]; other site
331111011961	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
331111011962	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
331111011963	Walker A/P-loop; other site
331111011964	ATP binding site [chemical binding]; other site
331111011965	Q-loop/lid; other site
331111011966	ABC transporter signature motif; other site
331111011967	Walker B; other site
331111011968	D-loop; other site
331111011969	H-loop/switch region; other site
331111011970	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
331111011971	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
331111011972	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
331111011973	TM-ABC transporter signature motif; other site
331111011974	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
331111011975	putative dimerization interface [polypeptide binding]; other site
331111011976	Transcriptional regulators [Transcription]; Region: PurR; COG1609
331111011977	putative ligand binding site [chemical binding]; other site
331111011978	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111011979	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
331111011980	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111011981	hypothetical protein; Provisional; Region: PRK10356
331111011982	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
331111011983	alpha-amylase; Reviewed; Region: malS; PRK09505
331111011984	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
331111011985	active site
331111011986	catalytic site [active]
331111011987	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
331111011988	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
331111011989	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111011990	homodimer interface [polypeptide binding]; other site
331111011991	catalytic residue [active]
331111011992	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
331111011993	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
331111011994	Transcriptional regulator [Transcription]; Region: IclR; COG1414
331111011995	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
331111011996	Bacterial transcriptional regulator; Region: IclR; pfam01614
331111011997	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
331111011998	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
331111011999	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
331111012000	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
331111012001	DctM-like transporters; Region: DctM; pfam06808
331111012002	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
331111012003	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
331111012004	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
331111012005	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
331111012006	putative N- and C-terminal domain interface [polypeptide binding]; other site
331111012007	putative active site [active]
331111012008	MgATP binding site [chemical binding]; other site
331111012009	catalytic site [active]
331111012010	metal binding site [ion binding]; metal-binding site
331111012011	putative xylulose binding site [chemical binding]; other site
331111012012	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
331111012013	active site
331111012014	dimer interface [polypeptide binding]; other site
331111012015	magnesium binding site [ion binding]; other site
331111012016	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
331111012017	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
331111012018	AP (apurinic/apyrimidinic) site pocket; other site
331111012019	DNA interaction; other site
331111012020	Metal-binding active site; metal-binding site
331111012021	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
331111012022	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
331111012023	intersubunit interface [polypeptide binding]; other site
331111012024	active site
331111012025	Zn2+ binding site [ion binding]; other site
331111012026	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
331111012027	Transcriptional regulator [Transcription]; Region: LysR; COG0583
331111012028	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111012029	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
331111012030	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
331111012031	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
331111012032	HlyD family secretion protein; Region: HlyD_3; pfam13437
331111012033	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
331111012034	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
331111012035	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
331111012036	NAD(P) binding site [chemical binding]; other site
331111012037	catalytic residues [active]
331111012038	putative alcohol dehydrogenase; Provisional; Region: PRK09860
331111012039	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
331111012040	dimer interface [polypeptide binding]; other site
331111012041	active site
331111012042	metal binding site [ion binding]; metal-binding site
331111012043	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
331111012044	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
331111012045	G1 box; other site
331111012046	putative GEF interaction site [polypeptide binding]; other site
331111012047	GTP/Mg2+ binding site [chemical binding]; other site
331111012048	Switch I region; other site
331111012049	G2 box; other site
331111012050	G3 box; other site
331111012051	Switch II region; other site
331111012052	G4 box; other site
331111012053	G5 box; other site
331111012054	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
331111012055	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
331111012056	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
331111012057	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
331111012058	selenocysteine synthase; Provisional; Region: PRK04311
331111012059	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
331111012060	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
331111012061	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
331111012062	catalytic residue [active]
331111012063	putative glutathione S-transferase; Provisional; Region: PRK10357
331111012064	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
331111012065	putative C-terminal domain interface [polypeptide binding]; other site
331111012066	putative GSH binding site (G-site) [chemical binding]; other site
331111012067	putative dimer interface [polypeptide binding]; other site
331111012068	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
331111012069	dimer interface [polypeptide binding]; other site
331111012070	N-terminal domain interface [polypeptide binding]; other site
331111012071	putative substrate binding pocket (H-site) [chemical binding]; other site
331111012072	PAAR motif; Region: PAAR_motif; cl15808
331111012073	RHS Repeat; Region: RHS_repeat; pfam05593
331111012074	RHS Repeat; Region: RHS_repeat; pfam05593
331111012075	RHS Repeat; Region: RHS_repeat; cl11982
331111012076	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
331111012077	RHS Repeat; Region: RHS_repeat; pfam05593
331111012078	RHS Repeat; Region: RHS_repeat; pfam05593
331111012079	RHS protein; Region: RHS; pfam03527
331111012080	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
331111012081	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
331111012082	putative lyase; Provisional; Region: PRK09687
331111012083	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
331111012084	RHS protein; Region: RHS; pfam03527
331111012085	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
331111012086	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
331111012087	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
331111012088	HlyD family secretion protein; Region: HlyD_3; pfam13437
331111012089	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
331111012090	Pleckstrin homology-like domain; Region: PH-like; cl17171
331111012091	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
331111012092	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
331111012093	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
331111012094	active site
331111012095	P-loop; other site
331111012096	phosphorylation site [posttranslational modification]
331111012097	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
331111012098	active site
331111012099	phosphorylation site [posttranslational modification]
331111012100	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
331111012101	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
331111012102	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
331111012103	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
331111012104	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
331111012105	hypothetical protein; Provisional; Region: PRK11020
331111012106	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
331111012107	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
331111012108	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
331111012109	trimer interface [polypeptide binding]; other site
331111012110	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
331111012111	trimer interface [polypeptide binding]; other site
331111012112	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
331111012113	Haemagglutinin; Region: HIM; pfam05662
331111012114	Haemagglutinin; Region: HIM; pfam05662
331111012115	YadA-like C-terminal region; Region: YadA; pfam03895
331111012116	L-lactate permease; Provisional; Region: PRK10420
331111012117	glycolate transporter; Provisional; Region: PRK09695
331111012118	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
331111012119	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111012120	DNA-binding site [nucleotide binding]; DNA binding site
331111012121	FCD domain; Region: FCD; pfam07729
331111012122	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
331111012123	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
331111012124	phosphate binding site [ion binding]; other site
331111012125	putative rRNA methylase; Provisional; Region: PRK10358
331111012126	serine acetyltransferase; Provisional; Region: cysE; PRK11132
331111012127	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
331111012128	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
331111012129	trimer interface [polypeptide binding]; other site
331111012130	active site
331111012131	substrate binding site [chemical binding]; other site
331111012132	CoA binding site [chemical binding]; other site
331111012133	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
331111012134	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
331111012135	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
331111012136	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
331111012137	SecA binding site; other site
331111012138	Preprotein binding site; other site
331111012139	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
331111012140	GSH binding site [chemical binding]; other site
331111012141	catalytic residues [active]
331111012142	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
331111012143	active site residue [active]
331111012144	phosphoglyceromutase; Provisional; Region: PRK05434
331111012145	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
331111012146	AmiB activator; Provisional; Region: PRK11637
331111012147	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
331111012148	Peptidase family M23; Region: Peptidase_M23; pfam01551
331111012149	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
331111012150	NodB motif; other site
331111012151	putative active site [active]
331111012152	putative catalytic site [active]
331111012153	Zn binding site [ion binding]; other site
331111012154	putative glycosyl transferase; Provisional; Region: PRK10073
331111012155	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
331111012156	active site
331111012157	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
331111012158	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
331111012159	NAD(P) binding site [chemical binding]; other site
331111012160	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
331111012161	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
331111012162	substrate-cofactor binding pocket; other site
331111012163	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111012164	catalytic residue [active]
331111012165	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
331111012166	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
331111012167	NADP binding site [chemical binding]; other site
331111012168	homopentamer interface [polypeptide binding]; other site
331111012169	substrate binding site [chemical binding]; other site
331111012170	active site
331111012171	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
331111012172	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
331111012173	putative active site [active]
331111012174	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
331111012175	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
331111012176	putative active site [active]
331111012177	O-Antigen ligase; Region: Wzy_C; pfam04932
331111012178	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
331111012179	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
331111012180	active site
331111012181	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
331111012182	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
331111012183	Ligand binding site; other site
331111012184	metal-binding site
331111012185	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
331111012186	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
331111012187	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
331111012188	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
331111012189	Ligand binding site; other site
331111012190	metal-binding site
331111012191	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
331111012192	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
331111012193	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
331111012194	Ligand binding site; other site
331111012195	metal-binding site
331111012196	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
331111012197	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
331111012198	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
331111012199	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
331111012200	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
331111012201	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
331111012202	putative active site [active]
331111012203	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
331111012204	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
331111012205	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
331111012206	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
331111012207	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
331111012208	active site
331111012209	(T/H)XGH motif; other site
331111012210	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
331111012211	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
331111012212	DNA binding site [nucleotide binding]
331111012213	catalytic residue [active]
331111012214	H2TH interface [polypeptide binding]; other site
331111012215	putative catalytic residues [active]
331111012216	turnover-facilitating residue; other site
331111012217	intercalation triad [nucleotide binding]; other site
331111012218	8OG recognition residue [nucleotide binding]; other site
331111012219	putative reading head residues; other site
331111012220	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
331111012221	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
331111012222	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
331111012223	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
331111012224	hypothetical protein; Reviewed; Region: PRK00024
331111012225	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
331111012226	MPN+ (JAMM) motif; other site
331111012227	Zinc-binding site [ion binding]; other site
331111012228	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
331111012229	Flavoprotein; Region: Flavoprotein; pfam02441
331111012230	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
331111012231	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
331111012232	trimer interface [polypeptide binding]; other site
331111012233	active site
331111012234	division inhibitor protein; Provisional; Region: slmA; PRK09480
331111012235	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
331111012236	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
331111012237	active site
331111012238	ribonuclease PH; Reviewed; Region: rph; PRK00173
331111012239	Ribonuclease PH; Region: RNase_PH_bact; cd11362
331111012240	hexamer interface [polypeptide binding]; other site
331111012241	active site
331111012242	hypothetical protein; Provisional; Region: PRK11820
331111012243	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
331111012244	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
331111012245	DNA-damage-inducible protein D; Provisional; Region: dinD; PRK11525
331111012246	BRO family, N-terminal domain; Region: Bro-N; pfam02498
331111012247	Predicted membrane protein [Function unknown]; Region: COG2860
331111012248	UPF0126 domain; Region: UPF0126; pfam03458
331111012249	UPF0126 domain; Region: UPF0126; pfam03458
331111012250	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
331111012251	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
331111012252	nucleotide binding pocket [chemical binding]; other site
331111012253	K-X-D-G motif; other site
331111012254	catalytic site [active]
331111012255	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
331111012256	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
331111012257	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
331111012258	catalytic site [active]
331111012259	G-X2-G-X-G-K; other site
331111012260	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
331111012261	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
331111012262	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
331111012263	Zn2+ binding site [ion binding]; other site
331111012264	Mg2+ binding site [ion binding]; other site
331111012265	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
331111012266	synthetase active site [active]
331111012267	NTP binding site [chemical binding]; other site
331111012268	metal binding site [ion binding]; metal-binding site
331111012269	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
331111012270	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
331111012271	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
331111012272	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
331111012273	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
331111012274	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
331111012275	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
331111012276	generic binding surface II; other site
331111012277	ssDNA binding site; other site
331111012278	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
331111012279	ATP binding site [chemical binding]; other site
331111012280	putative Mg++ binding site [ion binding]; other site
331111012281	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111012282	nucleotide binding region [chemical binding]; other site
331111012283	ATP-binding site [chemical binding]; other site
331111012284	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
331111012285	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
331111012286	AsmA family; Region: AsmA; pfam05170
331111012287	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
331111012288	putative alpha-glucosidase; Provisional; Region: PRK10658
331111012289	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
331111012290	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
331111012291	active site
331111012292	homotrimer interface [polypeptide binding]; other site
331111012293	catalytic site [active]
331111012294	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
331111012295	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
331111012296	putative transporter; Provisional; Region: PRK11462
331111012297	sugar efflux transporter; Region: 2A0120; TIGR00899
331111012298	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111012299	putative substrate translocation pore; other site
331111012300	EamA-like transporter family; Region: EamA; pfam00892
331111012301	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
331111012302	EamA-like transporter family; Region: EamA; pfam00892
331111012303	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
331111012304	lipoprotein, YaeC family; Region: TIGR00363
331111012305	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
331111012306	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
331111012307	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111012308	putative substrate translocation pore; other site
331111012309	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
331111012310	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
331111012311	cryptic adenine deaminase; Provisional; Region: PRK10027
331111012312	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
331111012313	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
331111012314	active site
331111012315	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
331111012316	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
331111012317	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111012318	putative substrate translocation pore; other site
331111012319	regulatory protein UhpC; Provisional; Region: PRK11663
331111012320	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111012321	putative substrate translocation pore; other site
331111012322	sensory histidine kinase UhpB; Provisional; Region: PRK11644
331111012323	MASE1; Region: MASE1; pfam05231
331111012324	Histidine kinase; Region: HisKA_3; pfam07730
331111012325	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
331111012326	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111012327	active site
331111012328	phosphorylation site [posttranslational modification]
331111012329	intermolecular recognition site; other site
331111012330	dimerization interface [polypeptide binding]; other site
331111012331	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111012332	DNA binding residues [nucleotide binding]
331111012333	dimerization interface [polypeptide binding]; other site
331111012334	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
331111012335	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
331111012336	putative valine binding site [chemical binding]; other site
331111012337	dimer interface [polypeptide binding]; other site
331111012338	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
331111012339	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
331111012340	PYR/PP interface [polypeptide binding]; other site
331111012341	dimer interface [polypeptide binding]; other site
331111012342	TPP binding site [chemical binding]; other site
331111012343	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
331111012344	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
331111012345	TPP-binding site [chemical binding]; other site
331111012346	dimer interface [polypeptide binding]; other site
331111012347	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
331111012348	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111012349	putative substrate translocation pore; other site
331111012350	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
331111012351	Domain of unknown function (DUF202); Region: DUF202; pfam02656
331111012352	Predicted membrane protein [Function unknown]; Region: COG2149
331111012353	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
331111012354	Sulfatase; Region: Sulfatase; pfam00884
331111012355	putative transporter; Provisional; Region: PRK10484
331111012356	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
331111012357	Na binding site [ion binding]; other site
331111012358	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
331111012359	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111012360	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
331111012361	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
331111012362	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
331111012363	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
331111012364	active site turn [active]
331111012365	phosphorylation site [posttranslational modification]
331111012366	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
331111012367	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111012368	DNA-binding site [nucleotide binding]; DNA binding site
331111012369	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
331111012370	putative transporter; Validated; Region: PRK03818
331111012371	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
331111012372	TrkA-C domain; Region: TrkA_C; pfam02080
331111012373	TrkA-C domain; Region: TrkA_C; pfam02080
331111012374	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
331111012375	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
331111012376	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
331111012377	putative dimer interface [polypeptide binding]; other site
331111012378	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
331111012379	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
331111012380	putative dimer interface [polypeptide binding]; other site
331111012381	hypothetical protein; Provisional; Region: PRK11616
331111012382	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
331111012383	putative oxidoreductase; Provisional; Region: PRK11445
331111012384	hypothetical protein; Provisional; Region: PRK07236
331111012385	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111012386	D-galactonate transporter; Region: 2A0114; TIGR00893
331111012387	putative substrate translocation pore; other site
331111012388	galactonate dehydratase; Provisional; Region: PRK14017
331111012389	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
331111012390	putative active site pocket [active]
331111012391	putative metal binding site [ion binding]; other site
331111012392	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
331111012393	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
331111012394	active site
331111012395	intersubunit interface [polypeptide binding]; other site
331111012396	catalytic residue [active]
331111012397	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
331111012398	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
331111012399	Transcriptional regulators [Transcription]; Region: FadR; COG2186
331111012400	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111012401	DNA-binding site [nucleotide binding]; DNA binding site
331111012402	FCD domain; Region: FCD; pfam07729
331111012403	hypothetical protein; Provisional; Region: PRK10215
331111012404	sugar phosphate phosphatase; Provisional; Region: PRK10513
331111012405	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111012406	active site
331111012407	motif I; other site
331111012408	motif II; other site
331111012409	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111012410	hypothetical protein; Provisional; Region: PRK11426
331111012411	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
331111012412	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111012413	Mg2+ binding site [ion binding]; other site
331111012414	G-X-G motif; other site
331111012415	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
331111012416	anchoring element; other site
331111012417	dimer interface [polypeptide binding]; other site
331111012418	ATP binding site [chemical binding]; other site
331111012419	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
331111012420	active site
331111012421	putative metal-binding site [ion binding]; other site
331111012422	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
331111012423	recF protein; Region: recf; TIGR00611
331111012424	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111012425	Walker A/P-loop; other site
331111012426	ATP binding site [chemical binding]; other site
331111012427	Q-loop/lid; other site
331111012428	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111012429	ABC transporter signature motif; other site
331111012430	Walker B; other site
331111012431	D-loop; other site
331111012432	H-loop/switch region; other site
331111012433	DNA polymerase III subunit beta; Validated; Region: PRK05643
331111012434	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
331111012435	putative DNA binding surface [nucleotide binding]; other site
331111012436	dimer interface [polypeptide binding]; other site
331111012437	beta-clamp/clamp loader binding surface; other site
331111012438	beta-clamp/translesion DNA polymerase binding surface; other site
331111012439	DnaA N-terminal domain; Region: DnaA_N; pfam11638
331111012440	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
331111012441	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111012442	Walker A motif; other site
331111012443	ATP binding site [chemical binding]; other site
331111012444	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
331111012445	Walker B motif; other site
331111012446	arginine finger; other site
331111012447	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
331111012448	DnaA box-binding interface [nucleotide binding]; other site
331111012449	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
331111012450	ribonuclease P; Reviewed; Region: rnpA; PRK01732
331111012451	membrane protein insertase; Provisional; Region: PRK01318
331111012452	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
331111012453	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
331111012454	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
331111012455	trmE is a tRNA modification GTPase; Region: trmE; cd04164
331111012456	G1 box; other site
331111012457	GTP/Mg2+ binding site [chemical binding]; other site
331111012458	Switch I region; other site
331111012459	G2 box; other site
331111012460	Switch II region; other site
331111012461	G3 box; other site
331111012462	G4 box; other site
331111012463	G5 box; other site
331111012464	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
331111012465	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
331111012466	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
331111012467	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
331111012468	catalytic residue [active]
331111012469	tryptophan permease TnaB; Provisional; Region: PRK09664
331111012470	aromatic amino acid transport protein; Region: araaP; TIGR00837
331111012471	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
331111012472	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111012473	putative substrate translocation pore; other site
331111012474	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
331111012475	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111012476	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
331111012477	substrate binding pocket [chemical binding]; other site
331111012478	dimerization interface [polypeptide binding]; other site
331111012479	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
331111012480	Predicted flavoprotein [General function prediction only]; Region: COG0431
331111012481	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
331111012482	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
331111012483	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
331111012484	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111012485	active site
331111012486	motif I; other site
331111012487	motif II; other site
331111012488	putative inner membrane protein; Provisional; Region: PRK09823
331111012489	Uncharacterized protein family (UPF0167); Region: UPF0167; cl01252
331111012490	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
331111012491	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
331111012492	active site
331111012493	trimer interface [polypeptide binding]; other site
331111012494	allosteric site; other site
331111012495	active site lid [active]
331111012496	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
331111012497	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
331111012498	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
331111012499	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
331111012500	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
331111012501	trimer interface; other site
331111012502	sugar binding site [chemical binding]; other site
331111012503	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
331111012504	beta-galactosidase; Region: BGL; TIGR03356
331111012505	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
331111012506	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
331111012507	active site turn [active]
331111012508	phosphorylation site [posttranslational modification]
331111012509	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
331111012510	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
331111012511	HPr interaction site; other site
331111012512	glycerol kinase (GK) interaction site [polypeptide binding]; other site
331111012513	active site
331111012514	phosphorylation site [posttranslational modification]
331111012515	transcriptional antiterminator BglG; Provisional; Region: PRK09772
331111012516	CAT RNA binding domain; Region: CAT_RBD; pfam03123
331111012517	PRD domain; Region: PRD; pfam00874
331111012518	PRD domain; Region: PRD; pfam00874
331111012519	transcriptional regulator PhoU; Provisional; Region: PRK11115
331111012520	PhoU domain; Region: PhoU; pfam01895
331111012521	PhoU domain; Region: PhoU; pfam01895
331111012522	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
331111012523	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
331111012524	Walker A/P-loop; other site
331111012525	ATP binding site [chemical binding]; other site
331111012526	Q-loop/lid; other site
331111012527	ABC transporter signature motif; other site
331111012528	Walker B; other site
331111012529	D-loop; other site
331111012530	H-loop/switch region; other site
331111012531	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
331111012532	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111012533	dimer interface [polypeptide binding]; other site
331111012534	conserved gate region; other site
331111012535	putative PBP binding loops; other site
331111012536	ABC-ATPase subunit interface; other site
331111012537	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
331111012538	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111012539	dimer interface [polypeptide binding]; other site
331111012540	conserved gate region; other site
331111012541	putative PBP binding loops; other site
331111012542	ABC-ATPase subunit interface; other site
331111012543	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111012544	Fimbrial protein; Region: Fimbrial; cl01416
331111012545	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
331111012546	PapC N-terminal domain; Region: PapC_N; pfam13954
331111012547	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
331111012548	PapC C-terminal domain; Region: PapC_C; pfam13953
331111012549	fimbrial chaperone protein; Provisional; Region: lfpB; PRK15290
331111012550	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
331111012551	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
331111012552	fimbrial protein; Provisional; Region: lpfA; PRK15289
331111012553	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
331111012554	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
331111012555	glutaminase active site [active]
331111012556	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
331111012557	dimer interface [polypeptide binding]; other site
331111012558	active site
331111012559	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
331111012560	dimer interface [polypeptide binding]; other site
331111012561	active site
331111012562	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
331111012563	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
331111012564	Substrate binding site; other site
331111012565	Mg++ binding site; other site
331111012566	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
331111012567	active site
331111012568	substrate binding site [chemical binding]; other site
331111012569	CoA binding site [chemical binding]; other site
331111012570	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
331111012571	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
331111012572	gamma subunit interface [polypeptide binding]; other site
331111012573	epsilon subunit interface [polypeptide binding]; other site
331111012574	LBP interface [polypeptide binding]; other site
331111012575	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
331111012576	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
331111012577	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
331111012578	alpha subunit interaction interface [polypeptide binding]; other site
331111012579	Walker A motif; other site
331111012580	ATP binding site [chemical binding]; other site
331111012581	Walker B motif; other site
331111012582	inhibitor binding site; inhibition site
331111012583	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
331111012584	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
331111012585	core domain interface [polypeptide binding]; other site
331111012586	delta subunit interface [polypeptide binding]; other site
331111012587	epsilon subunit interface [polypeptide binding]; other site
331111012588	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
331111012589	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
331111012590	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
331111012591	beta subunit interaction interface [polypeptide binding]; other site
331111012592	Walker A motif; other site
331111012593	ATP binding site [chemical binding]; other site
331111012594	Walker B motif; other site
331111012595	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
331111012596	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
331111012597	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
331111012598	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
331111012599	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
331111012600	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
331111012601	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
331111012602	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
331111012603	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
331111012604	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
331111012605	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
331111012606	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
331111012607	FMN-binding protein MioC; Provisional; Region: PRK09004
331111012608	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
331111012609	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
331111012610	putative DNA binding site [nucleotide binding]; other site
331111012611	putative Zn2+ binding site [ion binding]; other site
331111012612	AsnC family; Region: AsnC_trans_reg; pfam01037
331111012613	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
331111012614	dimer interface [polypeptide binding]; other site
331111012615	active site
331111012616	hypothetical protein; Provisional; Region: yieM; PRK10997
331111012617	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
331111012618	metal ion-dependent adhesion site (MIDAS); other site
331111012619	regulatory ATPase RavA; Provisional; Region: PRK13531
331111012620	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111012621	Walker A motif; other site
331111012622	ATP binding site [chemical binding]; other site
331111012623	Walker B motif; other site
331111012624	arginine finger; other site
331111012625	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
331111012626	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
331111012627	potassium uptake protein; Region: kup; TIGR00794
331111012628	D-ribose pyranase; Provisional; Region: PRK11797
331111012629	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
331111012630	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
331111012631	Walker A/P-loop; other site
331111012632	ATP binding site [chemical binding]; other site
331111012633	Q-loop/lid; other site
331111012634	ABC transporter signature motif; other site
331111012635	Walker B; other site
331111012636	D-loop; other site
331111012637	H-loop/switch region; other site
331111012638	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
331111012639	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
331111012640	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
331111012641	TM-ABC transporter signature motif; other site
331111012642	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
331111012643	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
331111012644	ligand binding site [chemical binding]; other site
331111012645	dimerization interface [polypeptide binding]; other site
331111012646	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
331111012647	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
331111012648	substrate binding site [chemical binding]; other site
331111012649	dimer interface [polypeptide binding]; other site
331111012650	ATP binding site [chemical binding]; other site
331111012651	transcriptional repressor RbsR; Provisional; Region: PRK10423
331111012652	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
331111012653	DNA binding site [nucleotide binding]
331111012654	domain linker motif; other site
331111012655	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
331111012656	dimerization interface [polypeptide binding]; other site
331111012657	ligand binding site [chemical binding]; other site
331111012658	putative transporter; Provisional; Region: PRK10504
331111012659	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111012660	putative substrate translocation pore; other site
331111012661	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111012662	Transcriptional regulators [Transcription]; Region: FadR; COG2186
331111012663	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111012664	DNA-binding site [nucleotide binding]; DNA binding site
331111012665	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
331111012666	transcriptional regulator HdfR; Provisional; Region: PRK03601
331111012667	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111012668	LysR substrate binding domain; Region: LysR_substrate; pfam03466
331111012669	dimerization interface [polypeptide binding]; other site
331111012670	hypothetical protein; Provisional; Region: PRK11027
331111012671	putative ATP-dependent protease; Provisional; Region: PRK09862
331111012672	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
331111012673	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111012674	Walker A motif; other site
331111012675	ATP binding site [chemical binding]; other site
331111012676	Walker B motif; other site
331111012677	arginine finger; other site
331111012678	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
331111012679	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
331111012680	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
331111012681	PYR/PP interface [polypeptide binding]; other site
331111012682	dimer interface [polypeptide binding]; other site
331111012683	TPP binding site [chemical binding]; other site
331111012684	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
331111012685	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
331111012686	TPP-binding site [chemical binding]; other site
331111012687	dimer interface [polypeptide binding]; other site
331111012688	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
331111012689	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
331111012690	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
331111012691	homodimer interface [polypeptide binding]; other site
331111012692	substrate-cofactor binding pocket; other site
331111012693	catalytic residue [active]
331111012694	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
331111012695	threonine dehydratase; Reviewed; Region: PRK09224
331111012696	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
331111012697	tetramer interface [polypeptide binding]; other site
331111012698	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111012699	catalytic residue [active]
331111012700	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
331111012701	putative Ile/Val binding site [chemical binding]; other site
331111012702	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
331111012703	putative Ile/Val binding site [chemical binding]; other site
331111012704	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111012705	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
331111012706	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
331111012707	putative dimerization interface [polypeptide binding]; other site
331111012708	ketol-acid reductoisomerase; Validated; Region: PRK05225
331111012709	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
331111012710	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
331111012711	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
331111012712	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
331111012713	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
331111012714	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3692
331111012715	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
331111012716	Part of AAA domain; Region: AAA_19; pfam13245
331111012717	Family description; Region: UvrD_C_2; pfam13538
331111012718	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
331111012719	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
331111012720	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
331111012721	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
331111012722	ATP binding site [chemical binding]; other site
331111012723	Mg++ binding site [ion binding]; other site
331111012724	motif III; other site
331111012725	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111012726	nucleotide binding region [chemical binding]; other site
331111012727	ATP-binding site [chemical binding]; other site
331111012728	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
331111012729	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
331111012730	catalytic residues [active]
331111012731	transcription termination factor Rho; Provisional; Region: rho; PRK09376
331111012732	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
331111012733	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
331111012734	RNA binding site [nucleotide binding]; other site
331111012735	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
331111012736	multimer interface [polypeptide binding]; other site
331111012737	Walker A motif; other site
331111012738	ATP binding site [chemical binding]; other site
331111012739	Walker B motif; other site
331111012740	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
331111012741	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
331111012742	Mg++ binding site [ion binding]; other site
331111012743	putative catalytic motif [active]
331111012744	substrate binding site [chemical binding]; other site
331111012745	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
331111012746	Chain length determinant protein; Region: Wzz; pfam02706
331111012747	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
331111012748	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
331111012749	active site
331111012750	homodimer interface [polypeptide binding]; other site
331111012751	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
331111012752	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
331111012753	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
331111012754	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
331111012755	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
331111012756	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
331111012757	NAD binding site [chemical binding]; other site
331111012758	substrate binding site [chemical binding]; other site
331111012759	homodimer interface [polypeptide binding]; other site
331111012760	active site
331111012761	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
331111012762	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
331111012763	substrate binding site; other site
331111012764	tetramer interface; other site
331111012765	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
331111012766	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
331111012767	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
331111012768	inhibitor-cofactor binding pocket; inhibition site
331111012769	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111012770	catalytic residue [active]
331111012771	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
331111012772	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
331111012773	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
331111012774	putative common antigen polymerase; Provisional; Region: PRK02975
331111012775	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
331111012776	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
331111012777	putative transport protein YifK; Provisional; Region: PRK10746
331111012778	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
331111012779	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111012780	FeS/SAM binding site; other site
331111012781	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
331111012782	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
331111012783	HemY protein N-terminus; Region: HemY_N; pfam07219
331111012784	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
331111012785	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
331111012786	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
331111012787	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
331111012788	active site
331111012789	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
331111012790	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
331111012791	domain interfaces; other site
331111012792	active site
331111012793	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
331111012794	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
331111012795	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
331111012796	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
331111012797	putative iron binding site [ion binding]; other site
331111012798	DKNYY family; Region: DKNYY; pfam13644
331111012799	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
331111012800	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
331111012801	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
331111012802	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
331111012803	hypothetical protein; Provisional; Region: PRK10963
331111012804	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
331111012805	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
331111012806	active site
331111012807	DNA binding site [nucleotide binding]
331111012808	Int/Topo IB signature motif; other site
331111012809	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
331111012810	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111012811	motif II; other site
331111012812	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
331111012813	Part of AAA domain; Region: AAA_19; pfam13245
331111012814	Family description; Region: UvrD_C_2; pfam13538
331111012815	Predicted periplasmic protein [Function unknown]; Region: COG3698
331111012816	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
331111012817	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
331111012818	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
331111012819	Cl binding site [ion binding]; other site
331111012820	oligomer interface [polypeptide binding]; other site
331111012821	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
331111012822	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
331111012823	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
331111012824	magnesium/nickel/cobalt transporter CorA; Provisional; Region: PRK11085
331111012825	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
331111012826	EamA-like transporter family; Region: EamA; cl17759
331111012827	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
331111012828	CoenzymeA binding site [chemical binding]; other site
331111012829	subunit interaction site [polypeptide binding]; other site
331111012830	PHB binding site; other site
331111012831	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
331111012832	dimerization interface [polypeptide binding]; other site
331111012833	substrate binding site [chemical binding]; other site
331111012834	active site
331111012835	calcium binding site [ion binding]; other site
331111012836	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
331111012837	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
331111012838	ATP binding site [chemical binding]; other site
331111012839	putative Mg++ binding site [ion binding]; other site
331111012840	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111012841	nucleotide binding region [chemical binding]; other site
331111012842	ATP-binding site [chemical binding]; other site
331111012843	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
331111012844	Helicase and RNase D C-terminal; Region: HRDC; smart00341
331111012845	threonine efflux system; Provisional; Region: PRK10229
331111012846	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
331111012847	lysophospholipase L2; Provisional; Region: PRK10749
331111012848	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
331111012849	putative hydrolase; Provisional; Region: PRK10976
331111012850	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111012851	active site
331111012852	motif I; other site
331111012853	motif II; other site
331111012854	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111012855	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
331111012856	EamA-like transporter family; Region: EamA; pfam00892
331111012857	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
331111012858	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111012859	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
331111012860	putative dimerization interface [polypeptide binding]; other site
331111012861	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
331111012862	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
331111012863	THF binding site; other site
331111012864	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
331111012865	substrate binding site [chemical binding]; other site
331111012866	THF binding site; other site
331111012867	zinc-binding site [ion binding]; other site
331111012868	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
331111012869	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
331111012870	uridine phosphorylase; Provisional; Region: PRK11178
331111012871	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
331111012872	DNA recombination protein RmuC; Provisional; Region: PRK10361
331111012873	RmuC family; Region: RmuC; pfam02646
331111012874	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
331111012875	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111012876	S-adenosylmethionine binding site [chemical binding]; other site
331111012877	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
331111012878	SCP-2 sterol transfer family; Region: SCP2; pfam02036
331111012879	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
331111012880	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
331111012881	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
331111012882	twin arginine translocase protein A; Provisional; Region: tatA; PRK00575
331111012883	sec-independent translocase; Provisional; Region: PRK01770
331111012884	sec-independent translocase; Provisional; Region: tatB; PRK00404
331111012885	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
331111012886	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
331111012887	active site
331111012888	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
331111012889	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
331111012890	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
331111012891	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
331111012892	FMN reductase; Validated; Region: fre; PRK08051
331111012893	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
331111012894	FAD binding pocket [chemical binding]; other site
331111012895	FAD binding motif [chemical binding]; other site
331111012896	phosphate binding motif [ion binding]; other site
331111012897	beta-alpha-beta structure motif; other site
331111012898	NAD binding pocket [chemical binding]; other site
331111012899	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
331111012900	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
331111012901	dimer interface [polypeptide binding]; other site
331111012902	active site
331111012903	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
331111012904	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
331111012905	substrate binding site [chemical binding]; other site
331111012906	oxyanion hole (OAH) forming residues; other site
331111012907	trimer interface [polypeptide binding]; other site
331111012908	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
331111012909	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
331111012910	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
331111012911	proline dipeptidase; Provisional; Region: PRK13607
331111012912	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
331111012913	active site
331111012914	hypothetical protein; Provisional; Region: PRK11568
331111012915	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
331111012916	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
331111012917	potassium transporter; Provisional; Region: PRK10750
331111012918	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
331111012919	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
331111012920	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
331111012921	Walker A motif; other site
331111012922	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
331111012923	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
331111012924	GTP binding site; other site
331111012925	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
331111012926	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
331111012927	serine/threonine protein kinase; Provisional; Region: PRK11768
331111012928	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
331111012929	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
331111012930	catalytic residues [active]
331111012931	hinge region; other site
331111012932	alpha helical domain; other site
331111012933	hypothetical protein; Provisional; Region: PRK11367
331111012934	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
331111012935	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
331111012936	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
331111012937	putative acyl-acceptor binding pocket; other site
331111012938	DNA polymerase I; Provisional; Region: PRK05755
331111012939	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
331111012940	active site
331111012941	metal binding site 1 [ion binding]; metal-binding site
331111012942	putative 5' ssDNA interaction site; other site
331111012943	metal binding site 3; metal-binding site
331111012944	metal binding site 2 [ion binding]; metal-binding site
331111012945	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
331111012946	putative DNA binding site [nucleotide binding]; other site
331111012947	putative metal binding site [ion binding]; other site
331111012948	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
331111012949	active site
331111012950	catalytic site [active]
331111012951	substrate binding site [chemical binding]; other site
331111012952	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
331111012953	active site
331111012954	DNA binding site [nucleotide binding]
331111012955	catalytic site [active]
331111012956	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
331111012957	G1 box; other site
331111012958	GTP/Mg2+ binding site [chemical binding]; other site
331111012959	Switch I region; other site
331111012960	G2 box; other site
331111012961	G3 box; other site
331111012962	Switch II region; other site
331111012963	G4 box; other site
331111012964	G5 box; other site
331111012965	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
331111012966	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
331111012967	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111012968	FeS/SAM binding site; other site
331111012969	HemN C-terminal domain; Region: HemN_C; pfam06969
331111012970	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
331111012971	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111012972	active site
331111012973	phosphorylation site [posttranslational modification]
331111012974	intermolecular recognition site; other site
331111012975	dimerization interface [polypeptide binding]; other site
331111012976	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111012977	Walker A motif; other site
331111012978	ATP binding site [chemical binding]; other site
331111012979	Walker B motif; other site
331111012980	arginine finger; other site
331111012981	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
331111012982	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
331111012983	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
331111012984	putative active site [active]
331111012985	heme pocket [chemical binding]; other site
331111012986	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111012987	dimer interface [polypeptide binding]; other site
331111012988	phosphorylation site [posttranslational modification]
331111012989	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111012990	ATP binding site [chemical binding]; other site
331111012991	Mg2+ binding site [ion binding]; other site
331111012992	G-X-G motif; other site
331111012993	glutamine synthetase; Provisional; Region: glnA; PRK09469
331111012994	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
331111012995	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
331111012996	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
331111012997	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
331111012998	G1 box; other site
331111012999	putative GEF interaction site [polypeptide binding]; other site
331111013000	GTP/Mg2+ binding site [chemical binding]; other site
331111013001	Switch I region; other site
331111013002	G2 box; other site
331111013003	G3 box; other site
331111013004	Switch II region; other site
331111013005	G4 box; other site
331111013006	G5 box; other site
331111013007	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
331111013008	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
331111013009	transcriptional regulator protein; Region: phnR; TIGR03337
331111013010	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111013011	DNA-binding site [nucleotide binding]; DNA binding site
331111013012	UTRA domain; Region: UTRA; pfam07702
331111013013	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
331111013014	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111013015	putative substrate translocation pore; other site
331111013016	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
331111013017	outer membrane porin L; Provisional; Region: ompL; PRK09980
331111013018	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
331111013019	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111013020	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
331111013021	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
331111013022	alpha-glucosidase; Provisional; Region: PRK10426
331111013023	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
331111013024	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
331111013025	putative active site [active]
331111013026	putative catalytic site [active]
331111013027	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
331111013028	active site
331111013029	catalytic residues [active]
331111013030	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
331111013031	dimerization interface [polypeptide binding]; other site
331111013032	putative active cleft [active]
331111013033	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
331111013034	catalytic residue [active]
331111013035	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
331111013036	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
331111013037	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
331111013038	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
331111013039	substrate binding site [chemical binding]; other site
331111013040	ATP binding site [chemical binding]; other site
331111013041	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
331111013042	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
331111013043	putative DNA binding site [nucleotide binding]; other site
331111013044	putative Zn2+ binding site [ion binding]; other site
331111013045	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
331111013046	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
331111013047	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111013048	motif II; other site
331111013049	hypothetical protein; Reviewed; Region: PRK01637
331111013050	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
331111013051	putative active site [active]
331111013052	dimerization interface [polypeptide binding]; other site
331111013053	putative tRNAtyr binding site [nucleotide binding]; other site
331111013054	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
331111013055	Coenzyme A binding pocket [chemical binding]; other site
331111013056	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
331111013057	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
331111013058	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
331111013059	substrate binding pocket [chemical binding]; other site
331111013060	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111013061	non-specific DNA binding site [nucleotide binding]; other site
331111013062	salt bridge; other site
331111013063	sequence-specific DNA binding site [nucleotide binding]; other site
331111013064	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
331111013065	Transposase; Region: DEDD_Tnp_IS110; pfam01548
331111013066	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
331111013067	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
331111013068	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
331111013069	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
331111013070	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
331111013071	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
331111013072	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
331111013073	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
331111013074	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
331111013075	putative frv operon regulatory protein; Provisional; Region: PRK09863
331111013076	HTH domain; Region: HTH_11; pfam08279
331111013077	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
331111013078	active site
331111013079	phosphorylation site [posttranslational modification]
331111013080	putative peptidase; Provisional; Region: PRK09864
331111013081	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
331111013082	oligomer interface [polypeptide binding]; other site
331111013083	active site
331111013084	metal binding site [ion binding]; metal-binding site
331111013085	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
331111013086	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
331111013087	active site
331111013088	P-loop; other site
331111013089	phosphorylation site [posttranslational modification]
331111013090	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
331111013091	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
331111013092	active site
331111013093	phosphorylation site [posttranslational modification]
331111013094	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
331111013095	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
331111013096	intersubunit interface [polypeptide binding]; other site
331111013097	active site
331111013098	Zn2+ binding site [ion binding]; other site
331111013099	L-rhamnose isomerase; Provisional; Region: PRK01076
331111013100	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
331111013101	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
331111013102	N- and C-terminal domain interface [polypeptide binding]; other site
331111013103	active site
331111013104	putative catalytic site [active]
331111013105	metal binding site [ion binding]; metal-binding site
331111013106	ATP binding site [chemical binding]; other site
331111013107	rhamnulokinase; Provisional; Region: rhaB; PRK10640
331111013108	carbohydrate binding site [chemical binding]; other site
331111013109	transcriptional activator RhaS; Provisional; Region: PRK13503
331111013110	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
331111013111	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111013112	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111013113	transcriptional activator RhaR; Provisional; Region: PRK13500
331111013114	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
331111013115	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111013116	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111013117	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
331111013118	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
331111013119	superoxide dismutase; Provisional; Region: PRK10925
331111013120	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
331111013121	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
331111013122	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
331111013123	2-keto-3-deoxygluconate transporter; Region: kdgT; TIGR00793
331111013124	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
331111013125	MOSC domain; Region: MOSC; pfam03473
331111013126	3-alpha domain; Region: 3-alpha; pfam03475
331111013127	two-component sensor protein; Provisional; Region: cpxA; PRK09470
331111013128	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
331111013129	dimerization interface [polypeptide binding]; other site
331111013130	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111013131	dimer interface [polypeptide binding]; other site
331111013132	phosphorylation site [posttranslational modification]
331111013133	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111013134	ATP binding site [chemical binding]; other site
331111013135	Mg2+ binding site [ion binding]; other site
331111013136	G-X-G motif; other site
331111013137	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
331111013138	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111013139	active site
331111013140	intermolecular recognition site; other site
331111013141	dimerization interface [polypeptide binding]; other site
331111013142	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
331111013143	DNA binding site [nucleotide binding]
331111013144	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
331111013145	dimer interface [polypeptide binding]; other site
331111013146	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
331111013147	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
331111013148	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
331111013149	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
331111013150	active site
331111013151	ADP/pyrophosphate binding site [chemical binding]; other site
331111013152	dimerization interface [polypeptide binding]; other site
331111013153	allosteric effector site; other site
331111013154	fructose-1,6-bisphosphate binding site; other site
331111013155	sulfate transporter subunit; Provisional; Region: PRK10752
331111013156	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
331111013157	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
331111013158	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
331111013159	triosephosphate isomerase; Provisional; Region: PRK14567
331111013160	substrate binding site [chemical binding]; other site
331111013161	dimer interface [polypeptide binding]; other site
331111013162	catalytic triad [active]
331111013163	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
331111013164	Predicted membrane protein [Function unknown]; Region: COG3152
331111013165	hypothetical protein; Provisional; Region: PRK09981
331111013166	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
331111013167	Ligand Binding Site [chemical binding]; other site
331111013168	ferredoxin-NADP reductase; Provisional; Region: PRK10926
331111013169	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
331111013170	FAD binding pocket [chemical binding]; other site
331111013171	FAD binding motif [chemical binding]; other site
331111013172	phosphate binding motif [ion binding]; other site
331111013173	beta-alpha-beta structure motif; other site
331111013174	NAD binding pocket [chemical binding]; other site
331111013175	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
331111013176	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
331111013177	putative active site [active]
331111013178	glycerol kinase; Provisional; Region: glpK; PRK00047
331111013179	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
331111013180	N- and C-terminal domain interface [polypeptide binding]; other site
331111013181	active site
331111013182	MgATP binding site [chemical binding]; other site
331111013183	catalytic site [active]
331111013184	metal binding site [ion binding]; metal-binding site
331111013185	glycerol binding site [chemical binding]; other site
331111013186	homotetramer interface [polypeptide binding]; other site
331111013187	homodimer interface [polypeptide binding]; other site
331111013188	FBP binding site [chemical binding]; other site
331111013189	protein IIAGlc interface [polypeptide binding]; other site
331111013190	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
331111013191	amphipathic channel; other site
331111013192	Asn-Pro-Ala signature motifs; other site
331111013193	septal ring assembly protein ZapB; Provisional; Region: PRK15422
331111013194	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
331111013195	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
331111013196	UbiA prenyltransferase family; Region: UbiA; pfam01040
331111013197	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
331111013198	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111013199	Walker A motif; other site
331111013200	ATP binding site [chemical binding]; other site
331111013201	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
331111013202	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
331111013203	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
331111013204	active site
331111013205	HslU subunit interaction site [polypeptide binding]; other site
331111013206	essential cell division protein FtsN; Provisional; Region: PRK10927
331111013207	cell division protein FtsN; Provisional; Region: PRK12757
331111013208	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
331111013209	DNA binding site [nucleotide binding]
331111013210	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
331111013211	domain linker motif; other site
331111013212	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
331111013213	dimerization interface [polypeptide binding]; other site
331111013214	ligand binding site [chemical binding]; other site
331111013215	primosome assembly protein PriA; Validated; Region: PRK05580
331111013216	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
331111013217	ATP binding site [chemical binding]; other site
331111013218	putative Mg++ binding site [ion binding]; other site
331111013219	helicase superfamily c-terminal domain; Region: HELICc; smart00490
331111013220	ATP-binding site [chemical binding]; other site
331111013221	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
331111013222	PAAR motif; Region: PAAR_motif; cl15808
331111013223	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
331111013224	RHS Repeat; Region: RHS_repeat; pfam05593
331111013225	RHS Repeat; Region: RHS_repeat; pfam05593
331111013226	RHS Repeat; Region: RHS_repeat; cl11982
331111013227	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
331111013228	RHS Repeat; Region: RHS_repeat; pfam05593
331111013229	RHS Repeat; Region: RHS_repeat; pfam05593
331111013230	RHS protein; Region: RHS; pfam03527
331111013231	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
331111013232	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
331111013233	hypothetical protein; Provisional; Region: PRK10030
331111013234	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
331111013235	Transposase; Region: DEDD_Tnp_IS110; pfam01548
331111013236	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
331111013237	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
331111013238	dimerization interface [polypeptide binding]; other site
331111013239	DNA binding site [nucleotide binding]
331111013240	corepressor binding sites; other site
331111013241	cystathionine gamma-synthase; Provisional; Region: PRK08045
331111013242	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
331111013243	homodimer interface [polypeptide binding]; other site
331111013244	substrate-cofactor binding pocket; other site
331111013245	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111013246	catalytic residue [active]
331111013247	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
331111013248	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
331111013249	putative catalytic residues [active]
331111013250	putative nucleotide binding site [chemical binding]; other site
331111013251	putative aspartate binding site [chemical binding]; other site
331111013252	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
331111013253	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
331111013254	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
331111013255	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
331111013256	FAD binding site [chemical binding]; other site
331111013257	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
331111013258	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
331111013259	heme binding site [chemical binding]; other site
331111013260	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
331111013261	EamA-like transporter family; Region: EamA; pfam00892
331111013262	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
331111013263	EamA-like transporter family; Region: EamA; pfam00892
331111013264	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
331111013265	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
331111013266	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
331111013267	dimer interface [polypeptide binding]; other site
331111013268	active site
331111013269	metal binding site [ion binding]; metal-binding site
331111013270	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
331111013271	active site
331111013272	intersubunit interactions; other site
331111013273	catalytic residue [active]
331111013274	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
331111013275	dimerization domain swap beta strand [polypeptide binding]; other site
331111013276	regulatory protein interface [polypeptide binding]; other site
331111013277	active site
331111013278	regulatory phosphorylation site [posttranslational modification]; other site
331111013279	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
331111013280	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
331111013281	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
331111013282	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
331111013283	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
331111013284	active site
331111013285	phosphorylation site [posttranslational modification]
331111013286	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
331111013287	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
331111013288	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
331111013289	active site
331111013290	P-loop; other site
331111013291	phosphorylation site [posttranslational modification]
331111013292	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
331111013293	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
331111013294	dimer interface [polypeptide binding]; other site
331111013295	active site
331111013296	glycine loop; other site
331111013297	pyruvate formate lyase II activase; Provisional; Region: PRK10076
331111013298	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
331111013299	active site
331111013300	P-loop; other site
331111013301	phosphorylation site [posttranslational modification]
331111013302	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
331111013303	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111013304	hypothetical protein; Provisional; Region: PRK10649
331111013305	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
331111013306	Sulfatase; Region: Sulfatase; pfam00884
331111013307	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
331111013308	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
331111013309	acetylornithine deacetylase; Provisional; Region: PRK05111
331111013310	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
331111013311	metal binding site [ion binding]; metal-binding site
331111013312	putative dimer interface [polypeptide binding]; other site
331111013313	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
331111013314	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
331111013315	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
331111013316	nucleotide binding site [chemical binding]; other site
331111013317	N-acetyl-L-glutamate binding site [chemical binding]; other site
331111013318	argininosuccinate lyase; Provisional; Region: PRK04833
331111013319	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
331111013320	active sites [active]
331111013321	tetramer interface [polypeptide binding]; other site
331111013322	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
331111013323	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
331111013324	putative active site pocket [active]
331111013325	putative metal binding site [ion binding]; other site
331111013326	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111013327	D-galactonate transporter; Region: 2A0114; TIGR00893
331111013328	putative substrate translocation pore; other site
331111013329	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
331111013330	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111013331	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
331111013332	dimerization interface [polypeptide binding]; other site
331111013333	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
331111013334	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
331111013335	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
331111013336	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
331111013337	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
331111013338	hypothetical protein; Provisional; Region: PRK11056
331111013339	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
331111013340	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111013341	S-adenosylmethionine binding site [chemical binding]; other site
331111013342	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
331111013343	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
331111013344	N-terminal plug; other site
331111013345	ligand-binding site [chemical binding]; other site
331111013346	glutamate racemase; Provisional; Region: PRK00865
331111013347	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
331111013348	FAD binding domain; Region: FAD_binding_4; pfam01565
331111013349	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
331111013350	Biotin operon repressor [Transcription]; Region: BirA; COG1654
331111013351	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
331111013352	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
331111013353	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
331111013354	pantothenate kinase; Provisional; Region: PRK05439
331111013355	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
331111013356	ATP-binding site [chemical binding]; other site
331111013357	CoA-binding site [chemical binding]; other site
331111013358	Mg2+-binding site [ion binding]; other site
331111013359	elongation factor Tu; Reviewed; Region: PRK00049
331111013360	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
331111013361	G1 box; other site
331111013362	GEF interaction site [polypeptide binding]; other site
331111013363	GTP/Mg2+ binding site [chemical binding]; other site
331111013364	Switch I region; other site
331111013365	G2 box; other site
331111013366	G3 box; other site
331111013367	Switch II region; other site
331111013368	G4 box; other site
331111013369	G5 box; other site
331111013370	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
331111013371	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
331111013372	Antibiotic Binding Site [chemical binding]; other site
331111013373	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
331111013374	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
331111013375	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
331111013376	putative homodimer interface [polypeptide binding]; other site
331111013377	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
331111013378	heterodimer interface [polypeptide binding]; other site
331111013379	homodimer interface [polypeptide binding]; other site
331111013380	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
331111013381	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
331111013382	23S rRNA interface [nucleotide binding]; other site
331111013383	L7/L12 interface [polypeptide binding]; other site
331111013384	putative thiostrepton binding site; other site
331111013385	L25 interface [polypeptide binding]; other site
331111013386	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
331111013387	mRNA/rRNA interface [nucleotide binding]; other site
331111013388	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
331111013389	23S rRNA interface [nucleotide binding]; other site
331111013390	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
331111013391	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
331111013392	core dimer interface [polypeptide binding]; other site
331111013393	peripheral dimer interface [polypeptide binding]; other site
331111013394	L10 interface [polypeptide binding]; other site
331111013395	L11 interface [polypeptide binding]; other site
331111013396	putative EF-Tu interaction site [polypeptide binding]; other site
331111013397	putative EF-G interaction site [polypeptide binding]; other site
331111013398	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
331111013399	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
331111013400	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
331111013401	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
331111013402	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
331111013403	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
331111013404	RPB3 interaction site [polypeptide binding]; other site
331111013405	RPB1 interaction site [polypeptide binding]; other site
331111013406	RPB11 interaction site [polypeptide binding]; other site
331111013407	RPB10 interaction site [polypeptide binding]; other site
331111013408	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
331111013409	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
331111013410	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
331111013411	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
331111013412	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
331111013413	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
331111013414	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
331111013415	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
331111013416	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
331111013417	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
331111013418	DNA binding site [nucleotide binding]
331111013419	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
331111013420	stationary phase growth adaptation protein; Provisional; Region: PRK09717
331111013421	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
331111013422	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111013423	FeS/SAM binding site; other site
331111013424	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
331111013425	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
331111013426	ThiS interaction site; other site
331111013427	putative active site [active]
331111013428	tetramer interface [polypeptide binding]; other site
331111013429	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
331111013430	thiS-thiF/thiG interaction site; other site
331111013431	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
331111013432	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
331111013433	ATP binding site [chemical binding]; other site
331111013434	substrate interface [chemical binding]; other site
331111013435	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
331111013436	thiamine phosphate binding site [chemical binding]; other site
331111013437	active site
331111013438	pyrophosphate binding site [ion binding]; other site
331111013439	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
331111013440	ThiC-associated domain; Region: ThiC-associated; pfam13667
331111013441	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
331111013442	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
331111013443	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
331111013444	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
331111013445	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
331111013446	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
331111013447	putative NADH binding site [chemical binding]; other site
331111013448	putative active site [active]
331111013449	nudix motif; other site
331111013450	putative metal binding site [ion binding]; other site
331111013451	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
331111013452	substrate binding site [chemical binding]; other site
331111013453	active site
331111013454	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
331111013455	Active_site [active]
331111013456	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
331111013457	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
331111013458	IHF dimer interface [polypeptide binding]; other site
331111013459	IHF - DNA interface [nucleotide binding]; other site
331111013460	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
331111013461	zinc resistance protein; Provisional; Region: zraP; PRK11546
331111013462	dimer interface [polypeptide binding]; other site
331111013463	sensor protein ZraS; Provisional; Region: PRK10364
331111013464	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111013465	dimer interface [polypeptide binding]; other site
331111013466	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111013467	ATP binding site [chemical binding]; other site
331111013468	Mg2+ binding site [ion binding]; other site
331111013469	G-X-G motif; other site
331111013470	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
331111013471	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111013472	active site
331111013473	phosphorylation site [posttranslational modification]
331111013474	intermolecular recognition site; other site
331111013475	dimerization interface [polypeptide binding]; other site
331111013476	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111013477	Walker A motif; other site
331111013478	ATP binding site [chemical binding]; other site
331111013479	Walker B motif; other site
331111013480	arginine finger; other site
331111013481	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
331111013482	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
331111013483	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
331111013484	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
331111013485	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
331111013486	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
331111013487	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
331111013488	purine monophosphate binding site [chemical binding]; other site
331111013489	dimer interface [polypeptide binding]; other site
331111013490	putative catalytic residues [active]
331111013491	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
331111013492	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
331111013493	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
331111013494	Coenzyme A binding pocket [chemical binding]; other site
331111013495	homoserine O-succinyltransferase; Provisional; Region: PRK05368
331111013496	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
331111013497	proposed active site lysine [active]
331111013498	conserved cys residue [active]
331111013499	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
331111013500	malate synthase A; Region: malate_syn_A; TIGR01344
331111013501	active site
331111013502	isocitrate lyase; Provisional; Region: PRK15063
331111013503	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
331111013504	tetramer interface [polypeptide binding]; other site
331111013505	active site
331111013506	Mg2+/Mn2+ binding site [ion binding]; other site
331111013507	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
331111013508	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
331111013509	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
331111013510	transcriptional repressor IclR; Provisional; Region: PRK11569
331111013511	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
331111013512	Bacterial transcriptional regulator; Region: IclR; pfam01614
331111013513	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
331111013514	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
331111013515	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
331111013516	substrate binding pocket [chemical binding]; other site
331111013517	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
331111013518	B12 binding site [chemical binding]; other site
331111013519	cobalt ligand [ion binding]; other site
331111013520	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
331111013521	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
331111013522	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
331111013523	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
331111013524	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
331111013525	active site pocket [active]
331111013526	oxyanion hole [active]
331111013527	catalytic triad [active]
331111013528	active site nucleophile [active]
331111013529	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
331111013530	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
331111013531	RNA binding surface [nucleotide binding]; other site
331111013532	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
331111013533	probable active site [active]
331111013534	hypothetical protein; Provisional; Region: PRK10515
331111013535	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
331111013536	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
331111013537	Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127
331111013538	Zeta toxin; Region: Zeta_toxin; pfam06414
331111013539	aspartate kinase III; Validated; Region: PRK09084
331111013540	AAK_AKiii-LysC-EC: Amino Acid Kinase Superfamily (AAK), AKiii-LysC-EC: this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKIII. AKIII is a monofunctional class enzyme (LysC) found in some...; Region: AAK_AKiii-LysC-EC; cd04258
331111013541	nucleotide binding site [chemical binding]; other site
331111013542	putative catalytic residues [active]
331111013543	aspartate binding site [chemical binding]; other site
331111013544	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
331111013545	lysine allosteric regulatory site; other site
331111013546	dimer interface [polypeptide binding]; other site
331111013547	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
331111013548	dimer interface [polypeptide binding]; other site
331111013549	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
331111013550	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
331111013551	active site
331111013552	dimer interface [polypeptide binding]; other site
331111013553	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
331111013554	dimer interface [polypeptide binding]; other site
331111013555	active site
331111013556	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
331111013557	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
331111013558	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
331111013559	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
331111013560	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
331111013561	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
331111013562	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111013563	putative substrate translocation pore; other site
331111013564	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111013565	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
331111013566	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111013567	dimer interface [polypeptide binding]; other site
331111013568	conserved gate region; other site
331111013569	putative PBP binding loops; other site
331111013570	ABC-ATPase subunit interface; other site
331111013571	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111013572	dimer interface [polypeptide binding]; other site
331111013573	conserved gate region; other site
331111013574	putative PBP binding loops; other site
331111013575	ABC-ATPase subunit interface; other site
331111013576	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
331111013577	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
331111013578	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
331111013579	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
331111013580	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
331111013581	Walker A/P-loop; other site
331111013582	ATP binding site [chemical binding]; other site
331111013583	Q-loop/lid; other site
331111013584	ABC transporter signature motif; other site
331111013585	Walker B; other site
331111013586	D-loop; other site
331111013587	H-loop/switch region; other site
331111013588	TOBE domain; Region: TOBE_2; pfam08402
331111013589	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
331111013590	trimer interface; other site
331111013591	sugar binding site [chemical binding]; other site
331111013592	maltose regulon periplasmic protein; Provisional; Region: PRK10564
331111013593	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
331111013594	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
331111013595	UbiA prenyltransferase family; Region: UbiA; pfam01040
331111013596	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
331111013597	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
331111013598	putative acyl-acceptor binding pocket; other site
331111013599	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
331111013600	LexA repressor; Validated; Region: PRK00215
331111013601	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
331111013602	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
331111013603	Catalytic site [active]
331111013604	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
331111013605	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
331111013606	hypothetical protein; Provisional; Region: PRK10428
331111013607	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
331111013608	metal binding site 2 [ion binding]; metal-binding site
331111013609	putative DNA binding helix; other site
331111013610	metal binding site 1 [ion binding]; metal-binding site
331111013611	dimer interface [polypeptide binding]; other site
331111013612	structural Zn2+ binding site [ion binding]; other site
331111013613	Protein of unknown function (DUF2713); Region: DUF2713; pfam10897
331111013614	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
331111013615	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
331111013616	FMN binding site [chemical binding]; other site
331111013617	active site
331111013618	catalytic residues [active]
331111013619	substrate binding site [chemical binding]; other site
331111013620	phage shock protein G; Reviewed; Region: pspG; PRK09459
331111013621	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
331111013622	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
331111013623	NADP binding site [chemical binding]; other site
331111013624	dimer interface [polypeptide binding]; other site
331111013625	replicative DNA helicase; Provisional; Region: PRK08006
331111013626	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
331111013627	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
331111013628	Walker A motif; other site
331111013629	ATP binding site [chemical binding]; other site
331111013630	Walker B motif; other site
331111013631	DNA binding loops [nucleotide binding]
331111013632	alanine racemase; Reviewed; Region: alr; PRK00053
331111013633	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
331111013634	active site
331111013635	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
331111013636	substrate binding site [chemical binding]; other site
331111013637	catalytic residues [active]
331111013638	dimer interface [polypeptide binding]; other site
331111013639	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
331111013640	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
331111013641	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111013642	homodimer interface [polypeptide binding]; other site
331111013643	catalytic residue [active]
331111013644	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111013645	active site
331111013646	motif I; other site
331111013647	motif II; other site
331111013648	Uncharacterized protein family UPF0047; Region: UPF0047; cl00439
331111013649	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
331111013650	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
331111013651	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
331111013652	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
331111013653	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
331111013654	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
331111013655	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
331111013656	dimer interface [polypeptide binding]; other site
331111013657	ssDNA binding site [nucleotide binding]; other site
331111013658	tetramer (dimer of dimers) interface [polypeptide binding]; other site
331111013659	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
331111013660	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
331111013661	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
331111013662	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
331111013663	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
331111013664	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111013665	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
331111013666	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
331111013667	DNA binding residues [nucleotide binding]
331111013668	dimer interface [polypeptide binding]; other site
331111013669	[2Fe-2S] cluster binding site [ion binding]; other site
331111013670	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
331111013671	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
331111013672	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
331111013673	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
331111013674	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
331111013675	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
331111013676	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
331111013677	Na binding site [ion binding]; other site
331111013678	Predicted membrane protein [Function unknown]; Region: COG3162
331111013679	acetyl-CoA synthetase; Provisional; Region: PRK00174
331111013680	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
331111013681	active site
331111013682	CoA binding site [chemical binding]; other site
331111013683	acyl-activating enzyme (AAE) consensus motif; other site
331111013684	AMP binding site [chemical binding]; other site
331111013685	acetate binding site [chemical binding]; other site
331111013686	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
331111013687	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
331111013688	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
331111013689	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
331111013690	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
331111013691	heme lyase subunit NrfE; Provisional; Region: PRK10369
331111013692	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
331111013693	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
331111013694	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
331111013695	binding surface
331111013696	TPR motif; other site
331111013697	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
331111013698	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
331111013699	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
331111013700	Sel1-like repeats; Region: SEL1; smart00671
331111013701	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
331111013702	molybdopterin cofactor binding site; other site
331111013703	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
331111013704	molybdopterin cofactor binding site; other site
331111013705	putative outer membrane efflux protein MdtP; Provisional; Region: PRK09915
331111013706	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
331111013707	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
331111013708	multidrug resistance protein MdtN; Provisional; Region: PRK10476
331111013709	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
331111013710	HlyD family secretion protein; Region: HlyD_3; pfam13437
331111013711	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
331111013712	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
331111013713	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
331111013714	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
331111013715	Coenzyme A binding pocket [chemical binding]; other site
331111013716	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
331111013717	AAA domain; Region: AAA_18; pfam13238
331111013718	active site
331111013719	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
331111013720	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
331111013721	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
331111013722	active site
331111013723	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
331111013724	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
331111013725	Walker A/P-loop; other site
331111013726	ATP binding site [chemical binding]; other site
331111013727	Q-loop/lid; other site
331111013728	ABC transporter signature motif; other site
331111013729	Walker B; other site
331111013730	D-loop; other site
331111013731	H-loop/switch region; other site
331111013732	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
331111013733	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
331111013734	Walker A/P-loop; other site
331111013735	ATP binding site [chemical binding]; other site
331111013736	Q-loop/lid; other site
331111013737	ABC transporter signature motif; other site
331111013738	Walker B; other site
331111013739	D-loop; other site
331111013740	H-loop/switch region; other site
331111013741	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
331111013742	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnJ; COG3627
331111013743	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnI; COG3626
331111013744	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnH; COG3625
331111013745	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
331111013746	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
331111013747	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111013748	DNA-binding site [nucleotide binding]; DNA binding site
331111013749	UTRA domain; Region: UTRA; pfam07702
331111013750	ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism]; Region: COG3639
331111013751	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
331111013752	dimer interface [polypeptide binding]; other site
331111013753	conserved gate region; other site
331111013754	putative PBP binding loops; other site
331111013755	ABC-ATPase subunit interface; other site
331111013756	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
331111013757	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
331111013758	substrate binding pocket [chemical binding]; other site
331111013759	membrane-bound complex binding site; other site
331111013760	hinge residues; other site
331111013761	phosphonate/organophosphate ester transporter subunit; Provisional; Region: PRK09984
331111013762	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
331111013763	Walker A/P-loop; other site
331111013764	ATP binding site [chemical binding]; other site
331111013765	Q-loop/lid; other site
331111013766	ABC transporter signature motif; other site
331111013767	Walker B; other site
331111013768	D-loop; other site
331111013769	H-loop/switch region; other site
331111013770	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
331111013771	dimer interface [polypeptide binding]; other site
331111013772	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
331111013773	hypothetical protein; Provisional; Region: PRK10220
331111013774	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
331111013775	PhnA protein; Region: PhnA; pfam03831
331111013776	hypothetical protein; Provisional; Region: PRK09866
331111013777	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
331111013778	G1 box; other site
331111013779	GTP/Mg2+ binding site [chemical binding]; other site
331111013780	G2 box; other site
331111013781	Switch I region; other site
331111013782	G3 box; other site
331111013783	Switch II region; other site
331111013784	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
331111013785	G2 box; other site
331111013786	Switch I region; other site
331111013787	G3 box; other site
331111013788	Switch II region; other site
331111013789	G4 box; other site
331111013790	G5 box; other site
331111013791	YjcZ-like protein; Region: YjcZ; pfam13990
331111013792	proline/glycine betaine transporter; Provisional; Region: PRK10642
331111013793	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111013794	putative substrate translocation pore; other site
331111013795	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
331111013796	sensor protein BasS/PmrB; Provisional; Region: PRK10755
331111013797	HAMP domain; Region: HAMP; pfam00672
331111013798	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111013799	dimer interface [polypeptide binding]; other site
331111013800	phosphorylation site [posttranslational modification]
331111013801	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111013802	ATP binding site [chemical binding]; other site
331111013803	Mg2+ binding site [ion binding]; other site
331111013804	G-X-G motif; other site
331111013805	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
331111013806	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111013807	active site
331111013808	phosphorylation site [posttranslational modification]
331111013809	intermolecular recognition site; other site
331111013810	dimerization interface [polypeptide binding]; other site
331111013811	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
331111013812	DNA binding site [nucleotide binding]
331111013813	putative metal dependent hydrolase; Provisional; Region: PRK11598
331111013814	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
331111013815	Sulfatase; Region: Sulfatase; pfam00884
331111013816	arginine:agmatin antiporter; Provisional; Region: PRK10644
331111013817	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
331111013818	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111013819	arginine decarboxylase; Provisional; Region: PRK15029
331111013820	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
331111013821	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
331111013822	homodimer interface [polypeptide binding]; other site
331111013823	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111013824	catalytic residue [active]
331111013825	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
331111013826	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
331111013827	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111013828	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111013829	alpha-galactosidase; Provisional; Region: PRK15076
331111013830	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
331111013831	NAD binding site [chemical binding]; other site
331111013832	sugar binding site [chemical binding]; other site
331111013833	divalent metal binding site [ion binding]; other site
331111013834	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
331111013835	dimer interface [polypeptide binding]; other site
331111013836	melibiose:sodium symporter; Provisional; Region: PRK10429
331111013837	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
331111013838	hypothetical protein; Provisional; Region: PRK09867
331111013839	fumarate hydratase; Provisional; Region: PRK15389
331111013840	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
331111013841	Fumarase C-terminus; Region: Fumerase_C; pfam05683
331111013842	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
331111013843	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111013844	active site
331111013845	phosphorylation site [posttranslational modification]
331111013846	intermolecular recognition site; other site
331111013847	dimerization interface [polypeptide binding]; other site
331111013848	Transcriptional regulator; Region: CitT; pfam12431
331111013849	sensory histidine kinase DcuS; Provisional; Region: PRK11086
331111013850	PAS domain; Region: PAS; smart00091
331111013851	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111013852	ATP binding site [chemical binding]; other site
331111013853	Mg2+ binding site [ion binding]; other site
331111013854	G-X-G motif; other site
331111013855	Uncharacterized conserved protein [Function unknown]; Region: COG3592
331111013856	Predicted acetyltransferase [General function prediction only]; Region: COG2388
331111013857	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
331111013858	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
331111013859	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
331111013860	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
331111013861	dimer interface [polypeptide binding]; other site
331111013862	putative anticodon binding site; other site
331111013863	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
331111013864	motif 1; other site
331111013865	active site
331111013866	motif 2; other site
331111013867	motif 3; other site
331111013868	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
331111013869	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111013870	putative substrate translocation pore; other site
331111013871	POT family; Region: PTR2; pfam00854
331111013872	lysine decarboxylase CadA; Provisional; Region: PRK15400
331111013873	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
331111013874	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
331111013875	homodimer interface [polypeptide binding]; other site
331111013876	pyridoxal 5'-phosphate binding site [chemical binding]; other site
331111013877	catalytic residue [active]
331111013878	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
331111013879	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
331111013880	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
331111013881	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
331111013882	DNA binding site [nucleotide binding]
331111013883	putative transcriptional regulator; Provisional; Region: PRK11640
331111013884	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
331111013885	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
331111013886	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
331111013887	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
331111013888	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
331111013889	DsbD alpha interface [polypeptide binding]; other site
331111013890	catalytic residues [active]
331111013891	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
331111013892	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
331111013893	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
331111013894	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
331111013895	Aspartase; Region: Aspartase; cd01357
331111013896	active sites [active]
331111013897	tetramer interface [polypeptide binding]; other site
331111013898	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
331111013899	putative transporter; Provisional; Region: PRK11021
331111013900	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
331111013901	oligomerisation interface [polypeptide binding]; other site
331111013902	mobile loop; other site
331111013903	roof hairpin; other site
331111013904	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
331111013905	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
331111013906	ring oligomerisation interface [polypeptide binding]; other site
331111013907	ATP/Mg binding site [chemical binding]; other site
331111013908	stacking interactions; other site
331111013909	hinge regions; other site
331111013910	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
331111013911	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
331111013912	Transposase; Region: DEDD_Tnp_IS110; pfam01548
331111013913	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
331111013914	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
331111013915	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
331111013916	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111013917	FeS/SAM binding site; other site
331111013918	elongation factor P; Validated; Region: PRK00529
331111013919	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
331111013920	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
331111013921	RNA binding site [nucleotide binding]; other site
331111013922	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
331111013923	RNA binding site [nucleotide binding]; other site
331111013924	entericidin A; Provisional; Region: PRK09810
331111013925	multidrug efflux system protein; Provisional; Region: PRK11431
331111013926	Bacterial lipocalin [Cell envelope biogenesis, outer membrane]; Region: Blc; COG3040
331111013927	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
331111013928	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
331111013929	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
331111013930	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
331111013931	Iron-sulfur protein interface; other site
331111013932	proximal quinone binding site [chemical binding]; other site
331111013933	C-subunit interface; other site
331111013934	distal quinone binding site; other site
331111013935	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
331111013936	D-subunit interface [polypeptide binding]; other site
331111013937	Iron-sulfur protein interface; other site
331111013938	proximal quinone binding site [chemical binding]; other site
331111013939	distal quinone binding site [chemical binding]; other site
331111013940	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
331111013941	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
331111013942	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
331111013943	L-aspartate oxidase; Provisional; Region: PRK06175
331111013944	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
331111013945	poxB regulator PoxA; Provisional; Region: PRK09350
331111013946	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
331111013947	motif 1; other site
331111013948	dimer interface [polypeptide binding]; other site
331111013949	active site
331111013950	motif 2; other site
331111013951	motif 3; other site
331111013952	inner membrane transporter YjeM; Provisional; Region: PRK15238
331111013953	putative mechanosensitive channel protein; Provisional; Region: PRK10929
331111013954	linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated...; Region: H15; cl00073
331111013955	DNA-binding site [nucleotide binding]; DNA binding site
331111013956	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
331111013957	Mechanosensitive ion channel; Region: MS_channel; pfam00924
331111013958	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
331111013959	GTPase RsgA; Reviewed; Region: PRK12288
331111013960	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
331111013961	RNA binding site [nucleotide binding]; other site
331111013962	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
331111013963	GTPase/Zn-binding domain interface [polypeptide binding]; other site
331111013964	GTP/Mg2+ binding site [chemical binding]; other site
331111013965	G4 box; other site
331111013966	G5 box; other site
331111013967	G1 box; other site
331111013968	Switch I region; other site
331111013969	G2 box; other site
331111013970	G3 box; other site
331111013971	Switch II region; other site
331111013972	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
331111013973	catalytic site [active]
331111013974	putative active site [active]
331111013975	putative substrate binding site [chemical binding]; other site
331111013976	dimer interface [polypeptide binding]; other site
331111013977	epoxyqueuosine reductase; Region: TIGR00276
331111013978	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
331111013979	putative carbohydrate kinase; Provisional; Region: PRK10565
331111013980	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
331111013981	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
331111013982	putative substrate binding site [chemical binding]; other site
331111013983	putative ATP binding site [chemical binding]; other site
331111013984	ADP-binding protein; Provisional; Region: PRK10646
331111013985	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
331111013986	AMIN domain; Region: AMIN; pfam11741
331111013987	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
331111013988	active site
331111013989	metal binding site [ion binding]; metal-binding site
331111013990	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
331111013991	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111013992	ATP binding site [chemical binding]; other site
331111013993	Mg2+ binding site [ion binding]; other site
331111013994	G-X-G motif; other site
331111013995	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
331111013996	ATP binding site [chemical binding]; other site
331111013997	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
331111013998	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
331111013999	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
331111014000	bacterial Hfq-like; Region: Hfq; cd01716
331111014001	hexamer interface [polypeptide binding]; other site
331111014002	Sm1 motif; other site
331111014003	RNA binding site [nucleotide binding]; other site
331111014004	Sm2 motif; other site
331111014005	GTPase HflX; Provisional; Region: PRK11058
331111014006	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
331111014007	HflX GTPase family; Region: HflX; cd01878
331111014008	G1 box; other site
331111014009	GTP/Mg2+ binding site [chemical binding]; other site
331111014010	Switch I region; other site
331111014011	G2 box; other site
331111014012	G3 box; other site
331111014013	Switch II region; other site
331111014014	G4 box; other site
331111014015	G5 box; other site
331111014016	FtsH protease regulator HflK; Provisional; Region: PRK10930
331111014017	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
331111014018	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
331111014019	FtsH protease regulator HflC; Provisional; Region: PRK11029
331111014020	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
331111014021	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
331111014022	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
331111014023	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
331111014024	GDP-binding site [chemical binding]; other site
331111014025	ACT binding site; other site
331111014026	IMP binding site; other site
331111014027	Predicted transcriptional regulator [Transcription]; Region: COG1959
331111014028	transcriptional repressor NsrR; Provisional; Region: PRK11014
331111014029	exoribonuclease R; Provisional; Region: PRK11642
331111014030	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
331111014031	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
331111014032	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
331111014033	RNB domain; Region: RNB; pfam00773
331111014034	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
331111014035	RNA binding site [nucleotide binding]; other site
331111014036	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
331111014037	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
331111014038	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
331111014039	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
331111014040	PspA/IM30 family; Region: PspA_IM30; pfam04012
331111014041	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
331111014042	Predicted membrane protein [Function unknown]; Region: COG3766
331111014043	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
331111014044	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
331111014045	Predicted integral membrane protein [Function unknown]; Region: COG5463
331111014046	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
331111014047	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
331111014048	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
331111014049	FAD binding site [chemical binding]; other site
331111014050	substrate binding site [chemical binding]; other site
331111014051	catalytic residues [active]
331111014052	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
331111014053	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
331111014054	esterase; Provisional; Region: PRK10566
331111014055	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
331111014056	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
331111014057	transcriptional repressor UlaR; Provisional; Region: PRK13509
331111014058	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
331111014059	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
331111014060	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
331111014061	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
331111014062	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
331111014063	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
331111014064	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
331111014065	active site
331111014066	phosphorylation site [posttranslational modification]
331111014067	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
331111014068	active site
331111014069	dimer interface [polypeptide binding]; other site
331111014070	magnesium binding site [ion binding]; other site
331111014071	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
331111014072	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
331111014073	AP (apurinic/apyrimidinic) site pocket; other site
331111014074	DNA interaction; other site
331111014075	Metal-binding active site; metal-binding site
331111014076	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
331111014077	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
331111014078	intersubunit interface [polypeptide binding]; other site
331111014079	active site
331111014080	Zn2+ binding site [ion binding]; other site
331111014081	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
331111014082	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
331111014083	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
331111014084	dimer interface [polypeptide binding]; other site
331111014085	ssDNA binding site [nucleotide binding]; other site
331111014086	tetramer (dimer of dimers) interface [polypeptide binding]; other site
331111014087	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
331111014088	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
331111014089	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
331111014090	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
331111014091	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
331111014092	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
331111014093	DctM-like transporters; Region: DctM; pfam06808
331111014094	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
331111014095	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Region: SdhA; COG1053
331111014096	L-aspartate oxidase; Provisional; Region: PRK06175
331111014097	L-aspartate oxidase; Provisional; Region: PRK06175
331111014098	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
331111014099	Coenzyme A transferase; Region: CoA_trans; smart00882
331111014100	Coenzyme A transferase; Region: CoA_trans; cl17247
331111014101	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
331111014102	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
331111014103	substrate binding site [chemical binding]; other site
331111014104	oxyanion hole (OAH) forming residues; other site
331111014105	trimer interface [polypeptide binding]; other site
331111014106	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
331111014107	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: PRK12745
331111014108	putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR), subgroup 1, classical (c) SDR; Region: BKR_1_SDR_c; cd05337
331111014109	putative NAD(P) binding site [chemical binding]; other site
331111014110	active site
331111014111	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
331111014112	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
331111014113	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
331111014114	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
331111014115	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
331111014116	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
331111014117	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
331111014118	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
331111014119	Hemerythrin-like domain; Region: Hr-like; cd12108
331111014120	Fe binding site [ion binding]; other site
331111014121	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
331111014122	EamA-like transporter family; Region: EamA; pfam00892
331111014123	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
331111014124	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
331111014125	NADP binding site [chemical binding]; other site
331111014126	Predicted transcriptional regulators [Transcription]; Region: COG1733
331111014127	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
331111014128	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
331111014129	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
331111014130	active site
331111014131	metal binding site [ion binding]; metal-binding site
331111014132	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
331111014133	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
331111014134	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
331111014135	active site
331111014136	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
331111014137	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
331111014138	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
331111014139	Domain of unknown function DUF21; Region: DUF21; pfam01595
331111014140	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
331111014141	Transporter associated domain; Region: CorC_HlyC; smart01091
331111014142	methionine sulfoxide reductase A; Provisional; Region: PRK00058
331111014143	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
331111014144	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
331111014145	Surface antigen; Region: Bac_surface_Ag; pfam01103
331111014146	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
331111014147	Family of unknown function (DUF490); Region: DUF490; pfam04357
331111014148	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
331111014149	putative active site pocket [active]
331111014150	dimerization interface [polypeptide binding]; other site
331111014151	putative catalytic residue [active]
331111014152	antitoxin ChpS; Provisional; Region: PRK11347
331111014153	toxin ChpB; Provisional; Region: PRK09812
331111014154	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
331111014155	dimer interface [polypeptide binding]; other site
331111014156	substrate binding site [chemical binding]; other site
331111014157	metal binding sites [ion binding]; metal-binding site
331111014158	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
331111014159	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
331111014160	putative ligand binding site [chemical binding]; other site
331111014161	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
331111014162	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
331111014163	Walker A/P-loop; other site
331111014164	ATP binding site [chemical binding]; other site
331111014165	Q-loop/lid; other site
331111014166	ABC transporter signature motif; other site
331111014167	Walker B; other site
331111014168	D-loop; other site
331111014169	H-loop/switch region; other site
331111014170	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
331111014171	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
331111014172	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
331111014173	TM-ABC transporter signature motif; other site
331111014174	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
331111014175	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
331111014176	TM-ABC transporter signature motif; other site
331111014177	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
331111014178	AMP binding site [chemical binding]; other site
331111014179	metal binding site [ion binding]; metal-binding site
331111014180	active site
331111014181	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
331111014182	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
331111014183	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
331111014184	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
331111014185	hypothetical protein; Provisional; Region: PRK05255
331111014186	peptidase PmbA; Provisional; Region: PRK11040
331111014187	cytochrome b562; Provisional; Region: PRK15058
331111014188	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
331111014189	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111014190	FeS/SAM binding site; other site
331111014191	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
331111014192	ATP cone domain; Region: ATP-cone; pfam03477
331111014193	Class III ribonucleotide reductase; Region: RNR_III; cd01675
331111014194	effector binding site; other site
331111014195	active site
331111014196	Zn binding site [ion binding]; other site
331111014197	glycine loop; other site
331111014198	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
331111014199	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
331111014200	Ca binding site [ion binding]; other site
331111014201	active site
331111014202	catalytic site [active]
331111014203	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
331111014204	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
331111014205	active site turn [active]
331111014206	phosphorylation site [posttranslational modification]
331111014207	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
331111014208	trehalose repressor; Provisional; Region: treR; PRK09492
331111014209	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
331111014210	DNA binding site [nucleotide binding]
331111014211	domain linker motif; other site
331111014212	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
331111014213	dimerization interface [polypeptide binding]; other site
331111014214	ligand binding site [chemical binding]; other site
331111014215	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
331111014216	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
331111014217	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
331111014218	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
331111014219	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111014220	motif II; other site
331111014221	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
331111014222	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
331111014223	Transposase; Region: DEDD_Tnp_IS110; pfam01548
331111014224	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
331111014225	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
331111014226	homotrimer interaction site [polypeptide binding]; other site
331111014227	putative active site [active]
331111014228	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
331111014229	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
331111014230	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
331111014231	aspartate carbamoyltransferase; Region: asp_carb_tr; TIGR00670
331111014232	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
331111014233	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
331111014234	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
331111014235	homotrimer interaction site [polypeptide binding]; other site
331111014236	putative active site [active]
331111014237	oxidoreductase; Provisional; Region: PRK12742
331111014238	classical (c) SDRs; Region: SDR_c; cd05233
331111014239	NAD(P) binding site [chemical binding]; other site
331111014240	active site
331111014241	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
331111014242	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
331111014243	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
331111014244	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
331111014245	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
331111014246	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
331111014247	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
331111014248	RNase E inhibitor protein; Provisional; Region: PRK11191
331111014249	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
331111014250	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
331111014251	Coenzyme A binding pocket [chemical binding]; other site
331111014252	Predicted membrane protein [Function unknown]; Region: COG4269
331111014253	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
331111014254	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
331111014255	HIGH motif; other site
331111014256	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
331111014257	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
331111014258	active site
331111014259	KMSKS motif; other site
331111014260	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
331111014261	tRNA binding surface [nucleotide binding]; other site
331111014262	anticodon binding site; other site
331111014263	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
331111014264	DNA polymerase III subunit chi; Validated; Region: PRK05728
331111014265	multifunctional aminopeptidase A; Provisional; Region: PRK00913
331111014266	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
331111014267	interface (dimer of trimers) [polypeptide binding]; other site
331111014268	Substrate-binding/catalytic site; other site
331111014269	Zn-binding sites [ion binding]; other site
331111014270	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
331111014271	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
331111014272	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
331111014273	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
331111014274	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
331111014275	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
331111014276	Walker A motif; other site
331111014277	ATP binding site [chemical binding]; other site
331111014278	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
331111014279	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
331111014280	putative NAD(P) binding site [chemical binding]; other site
331111014281	putative substrate binding site [chemical binding]; other site
331111014282	catalytic Zn binding site [ion binding]; other site
331111014283	structural Zn binding site [ion binding]; other site
331111014284	dimer interface [polypeptide binding]; other site
331111014285	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
331111014286	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
331111014287	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
331111014288	putative active site [active]
331111014289	putative NTP binding site [chemical binding]; other site
331111014290	putative nucleic acid binding site [nucleotide binding]; other site
331111014291	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
331111014292	Transposase; Region: HTH_Tnp_1; cl17663
331111014293	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111014294	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
331111014295	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
331111014296	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
331111014297	Transposase; Region: HTH_Tnp_1; cl17663
331111014298	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111014299	putative transposase OrfB; Reviewed; Region: PHA02517
331111014300	HTH-like domain; Region: HTH_21; pfam13276
331111014301	Integrase core domain; Region: rve; pfam00665
331111014302	Integrase core domain; Region: rve_2; pfam13333
331111014303	Predicted membrane protein [Function unknown]; Region: COG4325
331111014304	Predicted membrane protein (DUF2254); Region: DUF2254; pfam10011
331111014305	BCCT family transporter; Region: BCCT; cl00569
331111014306	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111014307	Transposase; Region: HTH_Tnp_1; pfam01527
331111014308	putative transposase OrfB; Reviewed; Region: PHA02517
331111014309	Integrase core domain; Region: rve; pfam00665
331111014310	Integrase core domain; Region: rve_3; pfam13683
331111014311	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
331111014312	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
331111014313	putative acyl-acceptor binding pocket; other site
331111014314	Protein of unknown function (DUF535); Region: DUF535; pfam04393
331111014315	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
331111014316	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
331111014317	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
331111014318	putative active site [active]
331111014319	putative metal binding site [ion binding]; other site
331111014320	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111014321	Transposase; Region: HTH_Tnp_1; cl17663
331111014322	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
331111014323	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
331111014324	putative active site [active]
331111014325	putative NTP binding site [chemical binding]; other site
331111014326	putative nucleic acid binding site [nucleotide binding]; other site
331111014327	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
331111014328	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
331111014329	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111014330	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
331111014331	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
331111014332	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111014333	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111014334	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111014335	Transposase; Region: HTH_Tnp_1; pfam01527
331111014336	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111014337	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
331111014338	iron-dicitrate transporter ATP-binding subunit; Provisional; Region: fecE; PRK11231
331111014339	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
331111014340	Walker A/P-loop; other site
331111014341	ATP binding site [chemical binding]; other site
331111014342	Q-loop/lid; other site
331111014343	ABC transporter signature motif; other site
331111014344	Walker B; other site
331111014345	D-loop; other site
331111014346	H-loop/switch region; other site
331111014347	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
331111014348	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
331111014349	ABC-ATPase subunit  interface; other site
331111014350	dimer interface [polypeptide binding]; other site
331111014351	putative PBP binding regions; other site
331111014352	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
331111014353	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
331111014354	dimer interface [polypeptide binding]; other site
331111014355	ABC-ATPase subunit  interface; other site
331111014356	putative PBP binding regions; other site
331111014357	iron-dicitrate transporter substrate-binding subunit; Provisional; Region: fecB; PRK11411
331111014358	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
331111014359	siderophore binding site; other site
331111014360	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
331111014361	Secretin and TonB N terminus short domain; Region: STN; smart00965
331111014362	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
331111014363	N-terminal plug; other site
331111014364	ligand-binding site [chemical binding]; other site
331111014365	fec operon regulator FecR; Reviewed; Region: PRK09774
331111014366	FecR protein; Region: FecR; pfam04773
331111014367	RNA polymerase sigma factor FecI; Provisional; Region: PRK09651
331111014368	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
331111014369	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
331111014370	DNA binding residues [nucleotide binding]
331111014371	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
331111014372	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
331111014373	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
331111014374	putative transposase OrfB; Reviewed; Region: PHA02517
331111014375	Esterase-like activity of phytase; Region: Phytase-like; pfam13449
331111014376	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111014377	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111014378	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
331111014379	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
331111014380	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111014381	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
331111014382	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
331111014383	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
331111014384	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
331111014385	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
331111014386	Transposase; Region: HTH_Tnp_1; pfam01527
331111014387	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
331111014388	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
331111014389	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
331111014390	Haemolysin expression modulating protein; Region: HHA; pfam05321
331111014391	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
331111014392	Predicted GTPase [General function prediction only]; Region: COG3596
331111014393	YfjP GTPase; Region: YfjP; cd11383
331111014394	G1 box; other site
331111014395	GTP/Mg2+ binding site [chemical binding]; other site
331111014396	Switch I region; other site
331111014397	G2 box; other site
331111014398	Switch II region; other site
331111014399	G3 box; other site
331111014400	G4 box; other site
331111014401	G5 box; other site
331111014402	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
331111014403	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
331111014404	hypothetical protein; Provisional; Region: PRK09945
331111014405	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
331111014406	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
331111014407	Autotransporter beta-domain; Region: Autotransporter; smart00869
331111014408	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
331111014409	Domain of unknown function (DUF932); Region: DUF932; pfam06067
331111014410	Antirestriction protein; Region: Antirestrict; pfam03230
331111014411	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
331111014412	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
331111014413	MPN+ (JAMM) motif; other site
331111014414	Zinc-binding site [ion binding]; other site
331111014415	Protein of unknown function (DUF987); Region: DUF987; pfam06174
331111014416	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
331111014417	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
331111014418	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
331111014419	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
331111014420	ATP binding site [chemical binding]; other site
331111014421	putative Mg++ binding site [ion binding]; other site
331111014422	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
331111014423	nucleotide binding region [chemical binding]; other site
331111014424	ATP-binding site [chemical binding]; other site
331111014425	ATP synthase subunit D; Region: ATP-synt_D; cl00613
331111014426	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
331111014427	DNA methylase; Region: N6_N4_Mtase; pfam01555
331111014428	DNA methylase; Region: N6_N4_Mtase; cl17433
331111014429	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
331111014430	HNH endonuclease; Region: HNH_2; pfam13391
331111014431	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3183
331111014432	Domain of unknown function (DUF303); Region: DUF303; pfam03629
331111014433	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
331111014434	Kelch motif; Region: Kelch_1; pfam01344
331111014435	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
331111014436	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
331111014437	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
331111014438	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
331111014439	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
331111014440	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
331111014441	PapC C-terminal domain; Region: PapC_C; pfam13953
331111014442	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
331111014443	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
331111014444	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
331111014445	mannosyl binding site [chemical binding]; other site
331111014446	Fimbrial protein; Region: Fimbrial; pfam00419
331111014447	fructuronate transporter; Provisional; Region: PRK10034
331111014448	gluconate transporter; Region: gntP; TIGR00791
331111014449	mannonate dehydratase; Region: uxuA; TIGR00695
331111014450	mannonate dehydratase; Provisional; Region: PRK03906
331111014451	D-mannonate oxidoreductase; Provisional; Region: PRK15037
331111014452	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
331111014453	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
331111014454	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
331111014455	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111014456	DNA-binding site [nucleotide binding]; DNA binding site
331111014457	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
331111014458	Glycine/serine hydroxymethyltransferase [Amino acid transport and metabolism]; Region: GlyA; COG0112
331111014459	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
331111014460	cell density-dependent motility repressor; Provisional; Region: PRK10082
331111014461	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
331111014462	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
331111014463	Isoaspartyl dipeptidase hydrolyzes the beta-L-isoaspartyl linkages in dipeptides, as part of the degradative pathway to eliminate proteins with beta-L-isoaspartyl peptide bonds, bonds whereby the beta-group of an aspartate forms the peptide link with the...; Region: Isoaspartyl-dipeptidase; cd01308
331111014464	isoaspartyl dipeptidase IadA; Region: isoAsp_dipep; TIGR01975
331111014465	dimer interface [polypeptide binding]; other site
331111014466	active site
331111014467	hypothetical protein; Provisional; Region: PRK10519
331111014468	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
331111014469	Nucleoside recognition; Region: Gate; pfam07670
331111014470	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
331111014471	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
331111014472	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
331111014473	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
331111014474	SdiA-regulated; Region: SdiA-regulated; cd09971
331111014475	putative active site [active]
331111014476	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
331111014477	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
331111014478	CoA-substrate-specific enzyme activase, putative; Region: CoA_E_activ; TIGR00241
331111014479	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
331111014480	benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263
331111014481	Predicted membrane protein [Function unknown]; Region: COG2733
331111014482	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
331111014483	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111014484	putative substrate translocation pore; other site
331111014485	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
331111014486	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
331111014487	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
331111014488	Protein of unknown function (DUF497); Region: DUF497; cl01108
331111014489	Domain of unknown function (DUF4415); Region: DUF4415; cl01401
331111014490	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
331111014491	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
331111014492	P-loop, Walker A motif; other site
331111014493	Base recognition motif; other site
331111014494	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
331111014495	Uncharacterized small protein [Function unknown]; Region: COG2879
331111014496	carbon starvation protein A; Provisional; Region: PRK15015
331111014497	Carbon starvation protein CstA; Region: CstA; pfam02554
331111014498	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
331111014499	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
331111014500	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
331111014501	dimer interface [polypeptide binding]; other site
331111014502	ligand binding site [chemical binding]; other site
331111014503	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
331111014504	dimerization interface [polypeptide binding]; other site
331111014505	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
331111014506	dimer interface [polypeptide binding]; other site
331111014507	putative CheW interface [polypeptide binding]; other site
331111014508	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
331111014509	D-galactonate transporter; Region: 2A0114; TIGR00893
331111014510	putative substrate translocation pore; other site
331111014511	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
331111014512	DNA-binding site [nucleotide binding]; DNA binding site
331111014513	Transcriptional regulators [Transcription]; Region: GntR; COG1802
331111014514	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
331111014515	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
331111014516	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
331111014517	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
331111014518	putative NAD(P) binding site [chemical binding]; other site
331111014519	catalytic Zn binding site [ion binding]; other site
331111014520	structural Zn binding site [ion binding]; other site
331111014521	phosphoglycerol transferase I; Provisional; Region: PRK03776
331111014522	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
331111014523	hypothetical protein; Provisional; Region: PRK11667
331111014524	DNA replication protein DnaC; Validated; Region: PRK07952
331111014525	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
331111014526	Walker A motif; other site
331111014527	ATP binding site [chemical binding]; other site
331111014528	Walker B motif; other site
331111014529	primosomal protein DnaI; Provisional; Region: PRK02854
331111014530	hypothetical protein; Provisional; Region: PRK09917
331111014531	Uncharacterized conserved protein [Function unknown]; Region: COG2966
331111014532	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
331111014533	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
331111014534	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111014535	DNA binding residues [nucleotide binding]
331111014536	dimerization interface [polypeptide binding]; other site
331111014537	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
331111014538	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
331111014539	DNA binding residues [nucleotide binding]
331111014540	dimerization interface [polypeptide binding]; other site
331111014541	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
331111014542	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
331111014543	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
331111014544	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
331111014545	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
331111014546	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
331111014547	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
331111014548	S-adenosylmethionine binding site [chemical binding]; other site
331111014549	DNA polymerase III subunit psi; Validated; Region: PRK06856
331111014550	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
331111014551	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
331111014552	Coenzyme A binding pocket [chemical binding]; other site
331111014553	dUMP phosphatase; Provisional; Region: PRK09449
331111014554	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111014555	motif II; other site
331111014556	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
331111014557	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
331111014558	G1 box; other site
331111014559	putative GEF interaction site [polypeptide binding]; other site
331111014560	GTP/Mg2+ binding site [chemical binding]; other site
331111014561	Switch I region; other site
331111014562	G2 box; other site
331111014563	G3 box; other site
331111014564	Switch II region; other site
331111014565	G4 box; other site
331111014566	G5 box; other site
331111014567	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
331111014568	periplasmic protein; Provisional; Region: PRK10568
331111014569	BON domain; Region: BON; pfam04972
331111014570	BON domain; Region: BON; pfam04972
331111014571	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
331111014572	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
331111014573	active site
331111014574	nucleophile elbow; other site
331111014575	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
331111014576	active site
331111014577	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
331111014578	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
331111014579	FeS/SAM binding site; other site
331111014580	hypothetical protein; Provisional; Region: PRK10977
331111014581	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
331111014582	intersubunit interface [polypeptide binding]; other site
331111014583	active site
331111014584	catalytic residue [active]
331111014585	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
331111014586	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
331111014587	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
331111014588	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
331111014589	phosphopentomutase; Provisional; Region: PRK05362
331111014590	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
331111014591	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
331111014592	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
331111014593	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
331111014594	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
331111014595	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
331111014596	hypothetical protein; Provisional; Region: PRK11246
331111014597	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
331111014598	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
331111014599	motif II; other site
331111014600	DNA repair protein RadA; Region: sms; TIGR00416
331111014601	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
331111014602	Walker A motif/ATP binding site; other site
331111014603	ATP binding site [chemical binding]; other site
331111014604	Walker B motif; other site
331111014605	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
331111014606	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
331111014607	non-specific DNA binding site [nucleotide binding]; other site
331111014608	salt bridge; other site
331111014609	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
331111014610	sequence-specific DNA binding site [nucleotide binding]; other site
331111014611	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
331111014612	active site
331111014613	(T/H)XGH motif; other site
331111014614	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
331111014615	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
331111014616	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
331111014617	Walker A/P-loop; other site
331111014618	ATP binding site [chemical binding]; other site
331111014619	Q-loop/lid; other site
331111014620	ABC transporter signature motif; other site
331111014621	Walker B; other site
331111014622	D-loop; other site
331111014623	H-loop/switch region; other site
331111014624	ABC transporter; Region: ABC_tran_2; pfam12848
331111014625	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
331111014626	lytic murein transglycosylase; Provisional; Region: PRK11619
331111014627	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
331111014628	N-acetyl-D-glucosamine binding site [chemical binding]; other site
331111014629	catalytic residue [active]
331111014630	Trp operon repressor; Provisional; Region: PRK01381
331111014631	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
331111014632	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
331111014633	catalytic core [active]
331111014634	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
331111014635	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
331111014636	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
331111014637	hypothetical protein; Provisional; Region: PRK10756
331111014638	CreA protein; Region: CreA; pfam05981
331111014639	DNA-binding response regulator CreB; Provisional; Region: PRK11083
331111014640	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111014641	active site
331111014642	phosphorylation site [posttranslational modification]
331111014643	intermolecular recognition site; other site
331111014644	dimerization interface [polypeptide binding]; other site
331111014645	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
331111014646	DNA binding site [nucleotide binding]
331111014647	sensory histidine kinase CreC; Provisional; Region: PRK11100
331111014648	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
331111014649	dimerization interface [polypeptide binding]; other site
331111014650	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
331111014651	dimer interface [polypeptide binding]; other site
331111014652	phosphorylation site [posttranslational modification]
331111014653	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
331111014654	ATP binding site [chemical binding]; other site
331111014655	Mg2+ binding site [ion binding]; other site
331111014656	G-X-G motif; other site
331111014657	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
331111014658	two-component response regulator; Provisional; Region: PRK11173
331111014659	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
331111014660	active site
331111014661	phosphorylation site [posttranslational modification]
331111014662	intermolecular recognition site; other site
331111014663	dimerization interface [polypeptide binding]; other site
331111014664	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
331111014665	DNA binding site [nucleotide binding]
331111014666	putative RNA methyltransferase; Provisional; Region: PRK10433
331111014667	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050