-- dump date 20140619_081951 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 331111000001 SEQ_END SEQ_END NC_009786.1 79237 79237 DR NC_009786.1; contig end 79237..79237 Escherichia coli E24377A 331111000002 SEQ_END SEQ_END NC_009787.1 34367 34367 DR NC_009787.1; contig end 34367..34367 Escherichia coli E24377A 331111000003 SEQ_END SEQ_END NC_009788.1 70609 70609 DR NC_009788.1; contig end 70609..70609 Escherichia coli E24377A 331111000004 SEQ_END SEQ_END NC_009789.1 6199 6199 DR NC_009789.1; contig end 6199..6199 Escherichia coli E24377A 331111000005 SEQ_END SEQ_END NC_009790.1 74224 74224 DR NC_009790.1; contig end 74224..74224 Escherichia coli E24377A 331111000006 SEQ_END SEQ_END NC_009791.1 5033 5033 DR NC_009791.1; contig end 5033..5033 Escherichia coli E24377A 331111000007 SEQ_END SEQ_END NC_009801.1 4979619 4979619 DR NC_009801.1; contig end 4979619..4979619 Escherichia coli E24377A YP_001451374.1 CDS EcE24377A_F0001 NC_009786.1 255 698 R identified by glimmer; putative; hypothetical protein complement(255..698) Escherichia coli E24377A 5585685 YP_001451375.1 CDS EcE24377A_F0002 NC_009786.1 1352 3262 D identified by similarity to GB:CAC92481.1; hypothetical protein 1352..3262 Escherichia coli E24377A 5585660 YP_001451376.1 CDS EcE24377A_F0003 NC_009786.1 3259 3753 D identified by glimmer; putative; hypothetical protein 3259..3753 Escherichia coli E24377A 5585705 YP_001451377.1 CDS EcE24377A_F0005 NC_009786.1 4316 5524 R identified by match to protein family HMM PF00872; IS1414, transposase complement(4316..5524) Escherichia coli E24377A 5585692 YP_001451378.1 CDS EcE24377A_F0006 NC_009786.1 5640 6656 R identified by match to protein family HMM PF02371; ISShdy1, transposase complement(5640..6656) Escherichia coli E24377A 5585625 YP_001451379.1 CDS EcE24377A_F0007 NC_009786.1 6771 6923 D identified by glimmer; putative; hypothetical protein 6771..6923 Escherichia coli E24377A 5585668 YP_001451380.1 CDS parM NC_009786.1 7123 8085 D identified by similarity to SP:P11904; match to protein family HMM PF06406; plasmid segregation protein ParM 7123..8085 Escherichia coli E24377A 5585683 YP_001451381.1 CDS EcE24377A_F0009 NC_009786.1 8505 9449 R identified by glimmer; putative; hypothetical protein complement(8505..9449) Escherichia coli E24377A 5585687 YP_001451382.1 CDS EcE24377A_F0010 NC_009786.1 9772 10053 R identified by match to protein family HMM PF01381; DNA-binding protein complement(9772..10053) Escherichia coli E24377A 5585680 YP_001451383.1 CDS EcE24377A_F0011 NC_009786.1 10034 10363 R identified by match to protein family HMM PF05973; prophage protein gp49 complement(10034..10363) Escherichia coli E24377A 5585672 YP_001451384.1 CDS EcE24377A_F0012 NC_009786.1 10457 10975 R IS3 family transposase complement(10457..10975) Escherichia coli E24377A 5585679 YP_001451385.1 CDS EcE24377A_F0014 NC_009786.1 12193 12384 R hypothetical protein complement(12193..12384) Escherichia coli E24377A 5585691 YP_001451386.1 CDS EcE24377A_F0016 NC_009786.1 13358 13804 R This gene is disrupted by the insertion of a group II intron.; identified by match to protein family HMM PF00665; IS629, transposase orfB, truncation complement(13358..13804) Escherichia coli E24377A 5585701 YP_001451387.1 CDS EcE24377A_F0017 NC_009786.1 13921 15429 R identified by match to protein family HMM PF00078; match to protein family HMM PF08388; group II intron-encoded reverse transcriptase/maturase complement(13921..15429) Escherichia coli E24377A 5585643 YP_001451388.1 CDS EcE24377A_F0018 NC_009786.1 16036 16146 R IS629, transposase orfB, truncation complement(16036..16146) Escherichia coli E24377A 5585665 YP_001451389.1 CDS EcE24377A_F0019 NC_009786.1 16130 16333 R identified by similarity to GB:ABB64661.1; hypothetical protein complement(16130..16333) Escherichia coli E24377A 5585658 YP_001451390.1 CDS eltA NC_009786.1 16616 17425 D identified by similarity to SP:P43530; match to protein family HMM PF01375; heat-labile enterotoxin A 16616..17425 Escherichia coli E24377A 5585630 YP_001451391.1 CDS EcE24377A_F0021 NC_009786.1 18117 18935 R identified by match to protein family HMM PF00665; ISSd1, transposase orfB complement(18117..18935) Escherichia coli E24377A 5585684 YP_001451392.1 CDS EcE24377A_F0022 NC_009786.1 19020 20171 R identified by match to protein family HMM PF00665; IS30, transposase complement(19020..20171) Escherichia coli E24377A 5585666 YP_001451393.1 CDS EcE24377A_F0024 NC_009786.1 20662 22626 D identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; plasmid partition protein B 20662..22626 Escherichia coli E24377A 5585626 YP_001451394.1 CDS psiB NC_009786.1 22681 23058 D identified by match to protein family HMM PF06290; plasmid SOS inhibition protein B 22681..23058 Escherichia coli E24377A 5585646 YP_001451395.1 CDS EcE24377A_F0026 NC_009786.1 23112 23873 D PsiA; plasmid SOS inhibition protein A 23112..23873 Escherichia coli E24377A 5585700 YP_001451396.1 CDS EcE24377A_F0027 NC_009786.1 23815 24129 D identified by similarity to GB:CAC86755.1; hypothetical protein 23815..24129 Escherichia coli E24377A 5585649 YP_001451397.1 CDS EcE24377A_F0028 NC_009786.1 25398 25568 D identified by glimmer; putative; hypothetical protein 25398..25568 Escherichia coli E24377A 5585694 YP_001451398.1 CDS traI NC_009786.1 25486 25602 D identified by similarity to SP:P14565; protein TraI 25486..25602 Escherichia coli E24377A 5585677 YP_001451399.1 CDS traX NC_009786.1 25622 26368 D identified by similarity to SP:P22710; match to protein family HMM PF05857; match to protein family HMM TIGR02755; conjugal transfer pilus acetylation protein TraX 25622..26368 Escherichia coli E24377A 5585695 YP_001451400.1 CDS EcE24377A_F0031 NC_009786.1 26427 27287 D identified by match to protein family HMM PF00561; alpha/beta fold family hydrolase 26427..27287 Escherichia coli E24377A 5585688 YP_001451401.2 CDS finO NC_009786.1 27390 27950 D identified by similarity to SP:P29367; match to protein family HMM PF05286; conjugal transfer fertility inhibition protein FinO 27390..27950 Escherichia coli E24377A 5585642 YP_001451402.1 CDS EcE24377A_F0033 NC_009786.1 28151 28333 R identified by glimmer; putative; hypothetical protein complement(28151..28333) Escherichia coli E24377A 5585639 YP_001451403.1 CDS EcE24377A_F0034 NC_009786.1 28194 28400 D identified by glimmer; putative; hypothetical protein 28194..28400 Escherichia coli E24377A 5585686 YP_001451404.1 CDS EcE24377A_F0035 NC_009786.1 28702 29328 D identified by glimmer; putative; hypothetical protein 28702..29328 Escherichia coli E24377A 5585669 YP_001451405.1 CDS EcE24377A_F0036 NC_009786.1 29480 30070 D identified by similarity to GB:AAM90728.1; hypothetical protein 29480..30070 Escherichia coli E24377A 5585635 YP_001451406.1 CDS repA NC_009786.1 30868 31725 D RepA; replication protein 30868..31725 Escherichia coli E24377A 5585671 YP_001451407.1 CDS EcE24377A_F0038 NC_009786.1 32696 33007 D identified by match to protein family HMM PF05973; prophage protein gp49 32696..33007 Escherichia coli E24377A 5585637 YP_001451408.1 CDS EcE24377A_F0039 NC_009786.1 33007 33294 D identified by match to protein family HMM PF01381; DNA-binding protein 33007..33294 Escherichia coli E24377A 5585652 YP_001451409.1 CDS def NC_009786.1 33671 34180 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 33671..34180 Escherichia coli E24377A 5585676 YP_001451410.1 CDS EcE24377A_F0041 NC_009786.1 34195 34311 D identified by glimmer; putative; hypothetical protein 34195..34311 Escherichia coli E24377A 5585623 YP_001451411.1 CDS EcE24377A_F0042 NC_009786.1 34817 35035 D IS630, transposase, truncation 34817..35035 Escherichia coli E24377A 5585661 YP_001451412.1 CDS EcE24377A_F0044 NC_009786.1 36107 37057 R identified by match to protein family HMM PF04393; hypothetical protein complement(36107..37057) Escherichia coli E24377A 5585628 YP_001451413.1 CDS EcE24377A_F0045 NC_009786.1 37062 38150 R identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein complement(37062..38150) Escherichia coli E24377A 5585673 YP_001451414.1 CDS EcE24377A_F0046 NC_009786.1 38153 38974 R identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein complement(38153..38974) Escherichia coli E24377A 5585624 YP_001451415.1 CDS EcE24377A_F0047 NC_009786.1 39239 39781 R identified by similarity to GB:AAZ89280.1; hypothetical protein complement(39239..39781) Escherichia coli E24377A 5585622 YP_001451416.1 CDS EcE24377A_F0048 NC_009786.1 39781 40038 R identified by similarity to GB:AAZ89279.1; hypothetical protein complement(39781..40038) Escherichia coli E24377A 5585662 YP_001451417.1 CDS ccdA2 NC_009786.1 40560 40778 D identified by similarity to SP:P62552; match to protein family HMM PF07362; plasmid maintenance protein CcdA 40560..40778 Escherichia coli E24377A 5585697 YP_001451418.1 CDS ccdB1 NC_009786.1 40780 41085 D controlled cell death protein; post-segregation toxin; toxin addiction system; plasmid maintenance protein CcdB 40780..41085 Escherichia coli E24377A 5585702 YP_001451419.1 CDS resD NC_009786.1 41086 41892 D identified by similarity to SP:P06615; match to protein family HMM PF00589; resolvase 41086..41892 Escherichia coli E24377A 5585654 YP_001451420.1 CDS EcE24377A_F0052 NC_009786.1 42070 42714 D identified by similarity to SP:P07175; ParA protein 42070..42714 Escherichia coli E24377A 5585629 YP_001451421.1 CDS EcE24377A_F0053 NC_009786.1 42801 43109 D identified by similarity to GB:AAK48856.1; putative 60 kDa chaperonin 42801..43109 Escherichia coli E24377A 5585651 YP_001451422.1 CDS EcE24377A_F0056 NC_009786.1 45986 46159 D hypothetical protein 45986..46159 Escherichia coli E24377A 5585636 YP_001451423.1 CDS EcE24377A_F0058 NC_009786.1 47406 48203 D identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein 47406..48203 Escherichia coli E24377A 5585632 YP_001451424.1 CDS EcE24377A_F0060 NC_009786.1 49061 49786 D identified by match to protein family HMM PF00345; match to protein family HMM PF02753; periplasmic pilus chaperone CS3-1 49061..49786 Escherichia coli E24377A 5585664 YP_001451425.1 CDS EcE24377A_F0062 NC_009786.1 54098 54520 D identified by similarity to GB:AAP16553.1; IS91, orf2 54098..54520 Escherichia coli E24377A 5585656 YP_001451426.1 CDS EcE24377A_F0064 NC_009786.1 55626 55901 D identified by match to protein family HMM PF03811; IS1, transposase orfA 55626..55901 Escherichia coli E24377A 5585703 YP_001451427.1 CDS EcE24377A_F0065 NC_009786.1 55820 56323 D identified by match to protein family HMM PF03400; IS1, transposase orfB 55820..56323 Escherichia coli E24377A 5585620 YP_001451428.1 CDS rns NC_009786.1 56818 57615 D identified by similarity to SP:P16114; match to protein family HMM PF00165; AraC family transcription regulator 56818..57615 Escherichia coli E24377A 5585640 YP_001451429.1 CDS EcE24377A_F0068 NC_009786.1 58816 59238 R identified by similarity to GB:AAP16553.1; IS91, orf2 complement(58816..59238) Escherichia coli E24377A 5585644 YP_001451430.1 CDS EcE24377A_F0070 NC_009786.1 60596 61735 D identified by match to protein family HMM PF02687; putative efflux ABC transporter, permease protein 60596..61735 Escherichia coli E24377A 5585670 YP_001451431.1 CDS EcE24377A_F0071 NC_009786.1 61768 62934 D identified by glimmer; putative; hypothetical protein 61768..62934 Escherichia coli E24377A 5585696 YP_001451432.1 CDS EcE24377A_F0072 NC_009786.1 62891 63664 D identified by glimmer; putative; hypothetical protein 62891..63664 Escherichia coli E24377A 5585675 YP_001451433.1 CDS EcE24377A_F0075 NC_009786.1 66131 66496 D IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 66131..66496 Escherichia coli E24377A 5585645 YP_001451434.1 CDS EcE24377A_F0076 NC_009786.1 66454 67365 D identified by similarity to SP:P51026; match to protein family HMM PF00665; IS2, transposase orfB 66454..67365 Escherichia coli E24377A 5585690 YP_001451435.1 CDS EcE24377A_F0077 NC_009786.1 68024 68308 D IS1414, transposase, truncation 68024..68308 Escherichia coli E24377A 5585647 YP_001451436.1 CDS EcE24377A_F0078 NC_009786.1 68336 68635 D identified by match to protein family HMM PF01527; IS3, transposase orfA 68336..68635 Escherichia coli E24377A 5585678 YP_001451437.1 CDS EcE24377A_F0081 NC_009786.1 69998 71284 R hypothetical protein complement(69998..71284) Escherichia coli E24377A 5585634 YP_001451438.1 CDS EcE24377A_F0083 NC_009786.1 72375 72674 R identified by match to protein family HMM PF01527; IS3, transposase orfA complement(72375..72674) Escherichia coli E24377A 5585633 YP_001451439.1 CDS EcE24377A_F0085 NC_009786.1 73885 74250 R identified by similarity to GB:AAP16553.1; IS91, orf2 complement(73885..74250) Escherichia coli E24377A 5585674 YP_001451440.1 CDS EcE24377A_F0086 NC_009786.1 74269 74940 D identified by match to protein family HMM PF00665; IS2, transposase orfB, truncation 74269..74940 Escherichia coli E24377A 5585621 YP_001451441.1 CDS EcE24377A_F0087 NC_009786.1 75209 76954 D identified by match to protein family HMM PF08479; hypothetical protein 75209..76954 Escherichia coli E24377A 5585653 YP_001451442.1 CDS traD NC_009787.1 4718 6949 R identified by similarity to SP:P22708; match to protein family HMM TIGR02759; type IV conjugative transfer system coupling protein TraD complement(4718..6949) Escherichia coli E24377A 5585707 YP_001451443.1 CDS traT NC_009787.1 7093 7830 R identified by similarity to SP:P13980; match to protein family HMM PF05818; TraT complement resistance protein complement(7093..7830) Escherichia coli E24377A 5585733 YP_001451444.1 CDS traG NC_009787.1 8583 11465 R identified by similarity to SP:P33790; match to protein family HMM PF07916; conjugal transfer mating pair stabilization protein TraG complement(8583..11465) Escherichia coli E24377A 5585727 YP_001451445.1 CDS traH NC_009787.1 11467 12972 R identified by similarity to SP:P15069; match to protein family HMM PF06122; conjugal transfer pilus assembly protein TraH complement(11467..12972) Escherichia coli E24377A 5585717 YP_001451446.1 CDS EcE24377A_C0005 NC_009787.1 12884 13753 R identified by similarity to GB:AAN52975.1; hypothetical protein complement(12884..13753) Escherichia coli E24377A 5585719 YP_001451447.1 CDS EcE24377A_C0006 NC_009787.1 14130 14270 R identified by glimmer; putative; hypothetical protein complement(14130..14270) Escherichia coli E24377A 5585716 YP_001451448.1 CDS EcE24377A_C0007 NC_009787.1 15035 15226 R hypothetical protein complement(15035..15226) Escherichia coli E24377A 5585735 YP_001451449.1 CDS EcE24377A_C0008 NC_009787.1 15223 15645 R identified by similarity to GB:AAS76405.1; hypothetical protein complement(15223..15645) Escherichia coli E24377A 5585720 YP_001451450.1 CDS EcE24377A_C0009 NC_009787.1 15692 16117 R identified by match to protein family HMM PF03230; antirestriction protein complement(15692..16117) Escherichia coli E24377A 5585718 YP_001451451.1 CDS EcE24377A_C0010 NC_009787.1 16529 17299 R identified by similarity to GB:BAB91623.1; hypothetical protein complement(16529..17299) Escherichia coli E24377A 5585729 YP_001451452.1 CDS EcE24377A_C0011 NC_009787.1 17344 17778 R identified by similarity to GB:AAR05672.1; match to protein family HMM PF07128; hypothetical protein complement(17344..17778) Escherichia coli E24377A 5585710 YP_001451453.1 CDS EcE24377A_C0012 NC_009787.1 17792 18013 R identified by similarity to GB:CAG27544.1; hypothetical protein complement(17792..18013) Escherichia coli E24377A 5585715 YP_001451454.1 CDS EcE24377A_C0013 NC_009787.1 18014 18697 R identified by match to protein family HMM PF01555; putative methylase complement(18014..18697) Escherichia coli E24377A 5585726 YP_001451455.1 CDS EcE24377A_C0014 NC_009787.1 18804 18929 D identified by similarity to GB:AAS76411.1; hypothetical protein 18804..18929 Escherichia coli E24377A 5585712 YP_001451456.1 CDS EcE24377A_C0015 NC_009787.1 19081 20007 R identified by similarity to GB:AAS76414.1; match to protein family HMM PF06924; hypothetical protein complement(19081..20007) Escherichia coli E24377A 5585709 YP_001451457.1 CDS EcE24377A_C0016 NC_009787.1 20124 20249 D identified by similarity to GB:AAS76411.1; hypothetical protein 20124..20249 Escherichia coli E24377A 5585731 YP_001451458.1 CDS EcE24377A_C0017 NC_009787.1 20408 20836 R identified by similarity to SP:P11906; protein stbB complement(20408..20836) Escherichia coli E24377A 5585730 YP_001451459.1 CDS parM NC_009787.1 20833 21813 R identified by similarity to SP:P11904; match to protein family HMM PF06406; plasmid segregation protein ParM complement(20833..21813) Escherichia coli E24377A 5585711 YP_001451460.1 CDS EcE24377A_C0019 NC_009787.1 22556 23590 R identified by similarity to GB:CAD76448.1; hypothetical protein complement(22556..23590) Escherichia coli E24377A 5585722 YP_001451461.1 CDS EcE24377A_C0020 NC_009787.1 24197 25201 R identified by glimmer; putative; hypothetical protein complement(24197..25201) Escherichia coli E24377A 5585723 YP_001451462.1 CDS EcE24377A_C0021 NC_009787.1 25355 25630 R identified by match to protein family HMM PF05016; RelE/ParE family plasmid stabilization system protein complement(25355..25630) Escherichia coli E24377A 5585728 YP_001451463.1 CDS EcE24377A_C0022 NC_009787.1 25630 25908 R identified by match to protein family HMM PF01402; CopG family protein complement(25630..25908) Escherichia coli E24377A 5585724 YP_001451464.1 CDS EcE24377A_C0023 NC_009787.1 26436 26885 R identified by glimmer; putative; hypothetical protein complement(26436..26885) Escherichia coli E24377A 5585734 YP_001451465.1 CDS EcE24377A_C0024 NC_009787.1 27303 28130 D identified by glimmer; putative; hypothetical protein 27303..28130 Escherichia coli E24377A 5585714 YP_001451466.1 CDS repA NC_009787.1 29051 29908 R RepA; replication protein complement(29051..29908) Escherichia coli E24377A 5585732 YP_001451467.1 CDS srnB NC_009787.1 30630 30827 R identified by similarity to SP:P13970; match to protein family HMM PF01848; protein SrnB complement(30630..30827) Escherichia coli E24377A 5585721 YP_001451468.1 CDS EcE24377A_C0027 NC_009787.1 30904 31899 R identified by similarity to GB:BAB78149.1; hypothetical protein complement(30904..31899) Escherichia coli E24377A 5585725 YP_001451469.1 CDS traX NC_009787.1 32479 33237 R identified by similarity to SP:P22710; match to protein family HMM PF05857; match to protein family HMM TIGR02755; type-F conjugative transfer system pilin acetylase TraX complement(32479..33237) Escherichia coli E24377A 5585713 YP_001451470.1 CDS EcE24377A_C0029 NC_009787.1 33207 33773 R identified by similarity to GB:AAM90728.1; hypothetical protein complement(33207..33773) Escherichia coli E24377A 5585708 YP_001451471.1 CDS EcE24377A_D0001 NC_009788.1 903 1136 R identified by similarity to GB:AAR05684.1; match to protein family HMM PF06006; hypothetical protein complement(903..1136) Escherichia coli E24377A 5585790 YP_001451472.1 CDS EcE24377A_D0002 NC_009788.1 1194 1721 R identified by similarity to SP:P28043; match to protein family HMM PF00436; match to protein family HMM TIGR00621; single-stranded DNA-binding protein complement(1194..1721) Escherichia coli E24377A 5585773 YP_001451473.1 CDS EcE24377A_D0003 NC_009788.1 2491 2682 R identified by similarity to GB:AAS76404.1; hypothetical protein complement(2491..2682) Escherichia coli E24377A 5585807 YP_001451474.1 CDS EcE24377A_D0004 NC_009788.1 2679 3101 R identified by similarity to GB:AAR05676.1; hypothetical protein complement(2679..3101) Escherichia coli E24377A 5585746 YP_001451475.1 CDS EcE24377A_D0005 NC_009788.1 3148 3573 R identified by match to protein family HMM PF03230; antirestriction family protein complement(3148..3573) Escherichia coli E24377A 5585794 YP_001451476.1 CDS EcE24377A_D0006 NC_009788.1 3990 4760 R identified by similarity to GB:AAS76407.1; hypothetical protein complement(3990..4760) Escherichia coli E24377A 5585796 YP_001451477.1 CDS EcE24377A_D0007 NC_009788.1 4805 5239 R identified by similarity to GB:CAG27545.1; match to protein family HMM PF07128; hypothetical protein complement(4805..5239) Escherichia coli E24377A 5585762 YP_001451478.1 CDS EcE24377A_D0008 NC_009788.1 5253 5474 R identified by similarity to GB:AAS76409.1; hypothetical protein complement(5253..5474) Escherichia coli E24377A 5585739 YP_001451479.1 CDS EcE24377A_D0009 NC_009788.1 5475 6158 R identified by match to protein family HMM PF01555; putative methylase complement(5475..6158) Escherichia coli E24377A 5585786 YP_001451480.1 CDS EcE24377A_D0010 NC_009788.1 6266 6391 D identified by similarity to GB:AAS76411.1; hypothetical protein 6266..6391 Escherichia coli E24377A 5585759 YP_001451481.1 CDS EcE24377A_D0011 NC_009788.1 6542 7468 R identified by similarity to GB:AAL72290.1; match to protein family HMM PF06924; hypothetical protein complement(6542..7468) Escherichia coli E24377A 5585772 YP_001451482.1 CDS EcE24377A_D0012 NC_009788.1 8125 8517 R stable plasmid inheritance protein complement(8125..8517) Escherichia coli E24377A 5585771 YP_001451483.1 CDS parM NC_009788.1 8521 9495 R identified by similarity to SP:P11904; match to protein family HMM PF06406; plasmid segregation protein ParM complement(8521..9495) Escherichia coli E24377A 5585749 YP_001451484.1 CDS resD NC_009788.1 11342 12175 R identified by similarity to SP:P06615; match to protein family HMM PF00589; resolvase complement(11342..12175) Escherichia coli E24377A 5585744 YP_001451485.1 CDS EcE24377A_D0015 NC_009788.1 12129 12542 R identified by similarity to GB:AAA24254.1; hypothetical protein complement(12129..12542) Escherichia coli E24377A 5585764 YP_001451486.1 CDS EcE24377A_D0016 NC_009788.1 12578 12673 R identified by glimmer; putative; hypothetical protein complement(12578..12673) Escherichia coli E24377A 5585791 YP_001451487.1 CDS EcE24377A_D0017 NC_009788.1 13328 13744 D identified by match to protein family HMM PF01850; PilT domain-containing protein 13328..13744 Escherichia coli E24377A 5585801 YP_001451488.1 CDS EcE24377A_D0018 NC_009788.1 13906 16044 R identified by similarity to GB:AAM37285.1; hypothetical protein complement(13906..16044) Escherichia coli E24377A 5585750 YP_001451489.1 CDS EcE24377A_D0019 NC_009788.1 16360 17898 R identified by match to protein family HMM PF03050; IS66 family transposase complement(16360..17898) Escherichia coli E24377A 5585763 YP_001451490.1 CDS EcE24377A_D0020 NC_009788.1 17948 18295 R identified by match to protein family HMM PF05717; IS66 family orf2 complement(17948..18295) Escherichia coli E24377A 5585784 YP_001451491.1 CDS EcE24377A_D0021 NC_009788.1 18292 18681 R identified by match to protein family HMM PF01527; IS66 family orf1 complement(18292..18681) Escherichia coli E24377A 5585792 YP_001451492.1 CDS EcE24377A_D0022 NC_009788.1 18981 19097 D identified by similarity to GB:AAZ89279.1; hypothetical protein 18981..19097 Escherichia coli E24377A 5585776 YP_001451493.1 CDS EcE24377A_D0023 NC_009788.1 19097 19687 D identified by similarity to GB:AAZ89280.1; hypothetical protein 19097..19687 Escherichia coli E24377A 5585751 YP_001451494.1 CDS EcE24377A_D0024 NC_009788.1 19705 20052 R identified by similarity to GB:AAA23190.1; hypothetical protein complement(19705..20052) Escherichia coli E24377A 5585756 YP_001451495.1 CDS EcE24377A_D0026 NC_009788.1 20712 20996 D identified by glimmer; putative; hypothetical protein 20712..20996 Escherichia coli E24377A 5585748 YP_001451496.1 CDS EcE24377A_D0027 NC_009788.1 20996 21856 D identified by match to protein family HMM PF00165; AraC family transcriptional regulator 20996..21856 Escherichia coli E24377A 5585777 YP_001451497.1 CDS EcE24377A_D0028 NC_009788.1 22166 23368 D identified by match to protein family HMM PF01609; IS186, transposase 22166..23368 Escherichia coli E24377A 5585779 YP_001451498.1 CDS EcE24377A_D0030 NC_009788.1 24963 25055 R identified by glimmer; putative; hypothetical protein complement(24963..25055) Escherichia coli E24377A 5585740 YP_001451499.1 CDS EcE24377A_D0031 NC_009788.1 25398 26027 R identified by match to protein family HMM PF00165; AraC family transcriptional regulator complement(25398..26027) Escherichia coli E24377A 5585781 YP_001451500.1 CDS EcE24377A_D0032 NC_009788.1 27290 28060 R identified by match to protein family HMM PF08388; hypothetical protein complement(27290..28060) Escherichia coli E24377A 5585742 YP_001451501.1 CDS EcE24377A_D0033 NC_009788.1 28840 29205 D IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 28840..29205 Escherichia coli E24377A 5585743 YP_001451502.1 CDS EcE24377A_D0034 NC_009788.1 29163 30068 D IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 29163..30068 Escherichia coli E24377A 5585808 YP_001451503.1 CDS EcE24377A_D0035 NC_009788.1 30756 31847 R identified by match to protein family HMM PF07434; fimbrial protein complement(30756..31847) Escherichia coli E24377A 5585805 YP_001451504.1 CDS EcE24377A_D0036 NC_009788.1 31844 34462 R identified by similarity to GB:AAK97136.1; fimbrial usher family protein complement(31844..34462) Escherichia coli E24377A 5585758 YP_001451505.1 CDS EcE24377A_D0037 NC_009788.1 35110 35826 R identified by glimmer; putative; hypothetical protein complement(35110..35826) Escherichia coli E24377A 5585804 YP_001451506.1 CDS EcE24377A_D0038 NC_009788.1 35933 36262 D identified by glimmer; putative; hypothetical protein 35933..36262 Escherichia coli E24377A 5585810 YP_001451507.1 CDS EcE24377A_D0041 NC_009788.1 38505 38696 R identified by glimmer; putative; hypothetical protein complement(38505..38696) Escherichia coli E24377A 5585745 YP_001451508.1 CDS EcE24377A_D0042 NC_009788.1 38758 39552 R identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein complement(38758..39552) Escherichia coli E24377A 5585767 YP_001451509.1 CDS EcE24377A_D0043 NC_009788.1 39552 40724 R identified by similarity to SP:P15025; match to protein family HMM PF00665; IS21 family transposase complement(39552..40724) Escherichia coli E24377A 5585768 YP_001451510.1 CDS EcE24377A_D0044 NC_009788.1 41361 41555 R hypothetical protein complement(41361..41555) Escherichia coli E24377A 5585798 YP_001451511.1 CDS EcE24377A_D0045 NC_009788.1 41552 41821 R hypothetical protein complement(41552..41821) Escherichia coli E24377A 5585799 YP_001451512.1 CDS EcE24377A_D0046 NC_009788.1 41618 41728 D identified by glimmer; putative; hypothetical protein 41618..41728 Escherichia coli E24377A 5585800 YP_001451513.1 CDS repZ NC_009788.1 42732 43763 R identified by similarity to SP:P18023; replication initiation protein complement(42732..43763) Escherichia coli E24377A 5585770 YP_001451514.1 CDS EcE24377A_D0048 NC_009788.1 45646 46179 D identified by match to protein family HMM PF02357; transcription termination factor NusG domain-containing protein 45646..46179 Escherichia coli E24377A 5585806 YP_001451515.1 CDS EcE24377A_D0049 NC_009788.1 46432 47115 D hypothetical protein 46432..47115 Escherichia coli E24377A 5585761 YP_001451516.1 CDS EcE24377A_D0051 NC_009788.1 48744 49811 D identified by similarity to GB:AAL05516.1; PilL protein 48744..49811 Escherichia coli E24377A 5585736 YP_001451517.1 CDS EcE24377A_D0052 NC_009788.1 49811 50248 D identified by match to protein family HMM PF07419; PilM protein 49811..50248 Escherichia coli E24377A 5585787 YP_001451518.1 CDS EcE24377A_D0053 NC_009788.1 50477 50803 D identified by match to protein family HMM PF01527; IS629, transposase orfA 50477..50803 Escherichia coli E24377A 5585765 YP_001451519.1 CDS EcE24377A_D0055 NC_009788.1 51889 53397 D identified by match to protein family HMM PF00078; match to protein family HMM PF08388; group II intron-encoded reverse transcriptase/maturase 51889..53397 Escherichia coli E24377A 5585775 YP_001451520.1 CDS EcE24377A_D0057 NC_009788.1 53944 55716 D hypothetical protein 53944..55716 Escherichia coli E24377A 5585803 YP_001451521.1 CDS EcE24377A_D0058 NC_009788.1 55753 58452 R identified by match to protein family HMM PF03432; relaxase/mobilization nuclease domain-containing protein complement(55753..58452) Escherichia coli E24377A 5585795 YP_001451522.1 CDS EcE24377A_D0059 NC_009788.1 59029 59364 D hypothetical protein 59029..59364 Escherichia coli E24377A 5585809 YP_001451523.1 CDS EcE24377A_D0060 NC_009788.1 59450 60298 R hypothetical protein complement(59450..60298) Escherichia coli E24377A 5585780 YP_001451524.1 CDS EcE24377A_D0062 NC_009788.1 60879 60974 D hypothetical protein 60879..60974 Escherichia coli E24377A 5585737 YP_001451525.1 CDS EcE24377A_D0063 NC_009788.1 61001 62572 R identified by match to protein family HMM PF03050; IS66 family transposase complement(61001..62572) Escherichia coli E24377A 5585769 YP_001451526.1 CDS EcE24377A_D0064 NC_009788.1 62592 62939 R identified by match to protein family HMM PF05717; IS66 family orf2 complement(62592..62939) Escherichia coli E24377A 5585752 YP_001451527.1 CDS EcE24377A_D0065 NC_009788.1 62939 63616 R identified by match to protein family HMM PF01527; IS66 family orf1 complement(62939..63616) Escherichia coli E24377A 5585783 YP_001451528.1 CDS EcE24377A_D0066 NC_009788.1 63703 63837 D hypothetical protein 63703..63837 Escherichia coli E24377A 5585738 YP_001451529.1 CDS EcE24377A_D0067 NC_009788.1 63868 64026 R hypothetical protein complement(63868..64026) Escherichia coli E24377A 5585753 YP_001451530.1 CDS EcE24377A_D0068 NC_009788.1 64089 64979 R identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; putative transposase complement(64089..64979) Escherichia coli E24377A 5585788 YP_001451531.1 CDS EcE24377A_D0069 NC_009788.1 64976 65440 R hypothetical protein complement(64976..65440) Escherichia coli E24377A 5585802 YP_001451532.1 CDS EcE24377A_D0070 NC_009788.1 65542 65808 R hypothetical protein complement(65542..65808) Escherichia coli E24377A 5585782 YP_001451533.1 CDS EcE24377A_D0071 NC_009788.1 65902 66336 R hypothetical protein complement(65902..66336) Escherichia coli E24377A 5585797 YP_001451534.1 CDS EcE24377A_D0072 NC_009788.1 66580 66675 R identified by glimmer; putative; hypothetical protein complement(66580..66675) Escherichia coli E24377A 5585741 YP_001451535.1 CDS EcE24377A_D0073 NC_009788.1 67065 67625 R identified by match to protein family HMM PF07275; putative anti-restriction protein complement(67065..67625) Escherichia coli E24377A 5585789 YP_001451536.1 CDS EcE24377A_D0074 NC_009788.1 67697 68293 R identified by similarity to GB:BAB91633.1; hypothetical protein complement(67697..68293) Escherichia coli E24377A 5585755 YP_001451537.1 CDS EcE24377A_D0075 NC_009788.1 68290 69009 R PsiA; plasmid SOS inhibition protein A complement(68290..69009) Escherichia coli E24377A 5585793 YP_001451538.1 CDS psiB NC_009788.1 69006 69440 R identified by match to protein family HMM PF06290; plasmid SOS inhibition protein B complement(69006..69440) Escherichia coli E24377A 5585747 YP_001451539.1 CDS EcE24377A_B0001 NC_009789.1 665 781 R identified by glimmer; putative; hypothetical protein complement(665..781) Escherichia coli E24377A 5585816 YP_001451540.1 CDS EcE24377A_B0002 NC_009789.1 877 1026 D hypothetical protein 877..1026 Escherichia coli E24377A 5585815 YP_001451541.1 CDS EcE24377A_B0003 NC_009789.1 3372 3974 R identified by match to protein family HMM PF04655; streptomycin resistance protein, StrB complement(3372..3974) Escherichia coli E24377A 5585813 YP_001451542.1 CDS EcE24377A_B0004 NC_009789.1 4208 5011 R identified by similarity to SP:P18150; match to protein family HMM PF01636; streptomycin resistance protein, StrA complement(4208..5011) Escherichia coli E24377A 5585814 YP_001451543.1 CDS folP2 NC_009789.1 5072 5887 R sulfonamide resistance mechanism; identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496; dihydropteroate synthase complement(5072..5887) Escherichia coli E24377A 5585812 YP_001451544.1 CDS EcE24377A_E0001 NC_009790.1 1319 1900 R identified by match to protein family HMM PF04986; IS1294, transposase, truncation complement(1319..1900) Escherichia coli E24377A 5585828 YP_001451545.1 CDS EcE24377A_E0002 NC_009790.1 2161 3345 D identified by similarity to GB:CAD31269.1; hypothetical protein 2161..3345 Escherichia coli E24377A 5585833 YP_001451546.1 CDS EcE24377A_E0003 NC_009790.1 3514 4191 D identified by match to protein family HMM PF01527; IS66 family orf1 3514..4191 Escherichia coli E24377A 5585840 YP_001451547.1 CDS EcE24377A_E0004 NC_009790.1 4191 4538 D identified by match to protein family HMM PF05717; IS66 family orf2 4191..4538 Escherichia coli E24377A 5585878 YP_001451548.1 CDS EcE24377A_E0005 NC_009790.1 4558 6129 D identified by match to protein family HMM PF03050; IS66 family transposase 4558..6129 Escherichia coli E24377A 5585836 YP_001451549.1 CDS EcE24377A_E0006 NC_009790.1 6254 6619 D IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 6254..6619 Escherichia coli E24377A 5585823 YP_001451550.1 CDS EcE24377A_E0007 NC_009790.1 6577 6828 D IS2, transposase orfB, truncation 6577..6828 Escherichia coli E24377A 5585893 YP_001451551.1 CDS EcE24377A_E0008 NC_009790.1 7009 7182 R IS91, transposase, truncation complement(7009..7182) Escherichia coli E24377A 5585875 YP_001451552.1 CDS EcE24377A_E0009 NC_009790.1 7137 7502 R identified by similarity to GB:AAX22066.1; IS91, orf2 complement(7137..7502) Escherichia coli E24377A 5585881 YP_001451553.1 CDS EcE24377A_E0010 NC_009790.1 7779 8633 R identified by match to protein family HMM PF04986; IS91, transposase, truncation complement(7779..8633) Escherichia coli E24377A 5585847 YP_001451554.1 CDS EcE24377A_E0011 NC_009790.1 8644 9912 D identified by similarity to GB:AAR05685.1; hypothetical protein 8644..9912 Escherichia coli E24377A 5585877 YP_001451555.1 CDS psiB NC_009790.1 9967 10401 D identified by similarity to SP:P10032; match to protein family HMM PF06290; plasmid SOS inhibition protein B 9967..10401 Escherichia coli E24377A 5585822 YP_001451556.1 CDS EcE24377A_E0013 NC_009790.1 10398 11117 D PsiA; plasmid SOS inhibition protein A 10398..11117 Escherichia coli E24377A 5585851 YP_001451557.1 CDS EcE24377A_E0014 NC_009790.1 11971 12297 D identified by match to protein family HMM PF01527; IS629, transposase orfA 11971..12297 Escherichia coli E24377A 5585821 YP_001451558.1 CDS EcE24377A_E0016 NC_009790.1 13368 14891 D identified by match to protein family HMM PF00078; match to protein family HMM PF08388; group II intron-encoded reverse transcriptase/maturase 13368..14891 Escherichia coli E24377A 5585888 YP_001451559.1 CDS EcE24377A_E0018 NC_009790.1 15818 16612 R identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein complement(15818..16612) Escherichia coli E24377A 5585843 YP_001451560.1 CDS EcE24377A_E0019 NC_009790.1 16612 17784 R identified by similarity to SP:P15025; match to protein family HMM PF00665; IS21 family transposase complement(16612..17784) Escherichia coli E24377A 5585863 YP_001451561.1 CDS EcE24377A_E0020 NC_009790.1 18516 19442 R identified by similarity to GB:AAR05668.1; match to protein family HMM PF06924; hypothetical protein complement(18516..19442) Escherichia coli E24377A 5585838 YP_001451562.1 CDS sopB NC_009790.1 20027 20998 R SopB; plasmid-partitioning protein complement(20027..20998) Escherichia coli E24377A 5585853 YP_001451563.1 CDS sopA NC_009790.1 20998 22164 R identified by similarity to SP:P62556; match to protein family HMM PF00376; match to protein family HMM PF01656; plasmid-partitioning protein SopA complement(20998..22164) Escherichia coli E24377A 5585882 YP_001451564.1 CDS EcE24377A_E0023 NC_009790.1 22120 22272 D identified by glimmer; putative; hypothetical protein 22120..22272 Escherichia coli E24377A 5585825 YP_001451565.1 CDS EcE24377A_E0025 NC_009790.1 23260 24783 R identified by match to protein family HMM PF00078; match to protein family HMM PF08388; group II intron-encoded reverse transcriptase/maturase complement(23260..24783) Escherichia coli E24377A 5585830 YP_001451566.1 CDS EcE24377A_E0027 NC_009790.1 25854 26180 R identified by match to protein family HMM PF01527; IS629, transposase orfA complement(25854..26180) Escherichia coli E24377A 5585880 YP_001451567.1 CDS EcE24377A_E0028 NC_009790.1 27397 28182 D identified by match to protein family HMM PF01555; putative DNA methylase 27397..28182 Escherichia coli E24377A 5585834 YP_001451568.1 CDS EcE24377A_E0029 NC_009790.1 28349 29098 R identified by glimmer; putative; hypothetical protein complement(28349..29098) Escherichia coli E24377A 5585824 YP_001451569.1 CDS EcE24377A_E0030 NC_009790.1 29124 29264 D identified by glimmer; putative; hypothetical protein 29124..29264 Escherichia coli E24377A 5585831 YP_001451570.1 CDS EcE24377A_E0031 NC_009790.1 29643 31004 D identified by glimmer; putative; hypothetical protein 29643..31004 Escherichia coli E24377A 5585826 YP_001451571.1 CDS EcE24377A_E0032 NC_009790.1 31051 31614 D identified by glimmer; putative; hypothetical protein 31051..31614 Escherichia coli E24377A 5585861 YP_001451572.1 CDS EcE24377A_E0033 NC_009790.1 31654 31779 D identified by glimmer; putative; hypothetical protein 31654..31779 Escherichia coli E24377A 5585829 YP_001451573.1 CDS EcE24377A_E0034 NC_009790.1 32838 33659 D identified by similarity to GB:CAI07494.1; match to protein family HMM PF06067; hypothetical protein 32838..33659 Escherichia coli E24377A 5585818 YP_001451574.1 CDS EcE24377A_E0035 NC_009790.1 34347 35141 R identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein complement(34347..35141) Escherichia coli E24377A 5585866 YP_001451575.1 CDS EcE24377A_E0036 NC_009790.1 35141 36313 R identified by similarity to SP:P15025; match to protein family HMM PF00665; IS21 family transposase complement(35141..36313) Escherichia coli E24377A 5585879 YP_001451576.1 CDS EcE24377A_E0037 NC_009790.1 36400 36750 R hypothetical protein complement(36400..36750) Escherichia coli E24377A 5585884 YP_001451577.1 CDS EcE24377A_E0038 NC_009790.1 38653 40191 R identified by match to protein family HMM PF03050; IS66 family transposase complement(38653..40191) Escherichia coli E24377A 5585867 YP_001451578.1 CDS EcE24377A_E0039 NC_009790.1 40241 40588 R identified by match to protein family HMM PF05717; IS66 family orf2 complement(40241..40588) Escherichia coli E24377A 5585864 YP_001451579.1 CDS EcE24377A_E0040 NC_009790.1 40585 40974 R identified by match to protein family HMM PF01527; IS66 family orf1 complement(40585..40974) Escherichia coli E24377A 5585859 YP_001451580.1 CDS EcE24377A_E0041 NC_009790.1 41789 42154 D IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 41789..42154 Escherichia coli E24377A 5585854 YP_001451581.1 CDS EcE24377A_E0042 NC_009790.1 42112 43023 D identified by similarity to SP:P51026; match to protein family HMM PF00665; IS2, transposase orfB 42112..43023 Escherichia coli E24377A 5585869 YP_001451582.1 CDS EcE24377A_E0043 NC_009790.1 43189 43461 D identified by match to protein family HMM PF03811; IS1, transposase orfA 43189..43461 Escherichia coli E24377A 5585885 YP_001451583.1 CDS EcE24377A_E0044 NC_009790.1 43488 43883 D identified by match to protein family HMM PF03400; IS1, transposase orfB 43488..43883 Escherichia coli E24377A 5585890 YP_001451584.1 CDS EcE24377A_E0045 NC_009790.1 44240 44917 D identified by match to protein family HMM PF01527; IS66 family orf1 44240..44917 Escherichia coli E24377A 5585835 YP_001451585.1 CDS EcE24377A_E0046 NC_009790.1 44917 45264 D identified by match to protein family HMM PF05717; IS66 family orf2 44917..45264 Escherichia coli E24377A 5585871 YP_001451586.1 CDS EcE24377A_E0047 NC_009790.1 45284 46855 D identified by match to protein family HMM PF03050; IS66 family transposase 45284..46855 Escherichia coli E24377A 5585876 YP_001451587.1 CDS EcE24377A_E0049 NC_009790.1 47535 47810 R identified by match to protein family HMM PF03811; IS1, transposase orfA complement(47535..47810) Escherichia coli E24377A 5585817 YP_001451588.1 CDS eatA NC_009790.1 49306 53406 D identified by similarity to SP:Q84GK0; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; secreted serine peptidase EatA 49306..53406 Escherichia coli E24377A 5585855 YP_001451589.1 CDS ydeO NC_009790.1 53749 54471 R identified by similarity to SP:P76135; match to protein family HMM PF00165; HTH-type transcriptional regulator YdeO complement(53749..54471) Escherichia coli E24377A 5585874 YP_001451590.1 CDS EcE24377A_E0053 NC_009790.1 54701 55381 D identified by match to protein family HMM PF00563; EAL domain-containing protein 54701..55381 Escherichia coli E24377A 5585837 YP_001451591.1 CDS EcE24377A_E0054 NC_009790.1 55821 56462 R identified by match to protein family HMM PF00239; resolvase domain-containing protein complement(55821..56462) Escherichia coli E24377A 5585858 YP_001451592.1 CDS resD NC_009790.1 56792 57505 R identified by similarity to SP:P06615; match to protein family HMM PF00589; resolvase complement(56792..57505) Escherichia coli E24377A 5585883 YP_001451593.1 CDS ccdB2 NC_009790.1 57506 57811 R controlled cell death protein; post-segregation toxin; toxin addiction system; plasmid maintenance protein CcdB complement(57506..57811) Escherichia coli E24377A 5585827 YP_001451594.2 CDS ccdA1 NC_009790.1 57813 58031 R identified by similarity to SP:P62552; match to protein family HMM PF07362; plasmid maintenance protein CcdA complement(57813..58031) Escherichia coli E24377A 5585873 YP_001451595.1 CDS EcE24377A_E0058 NC_009790.1 58476 58733 D identified by similarity to GB:AAZ89279.1; hypothetical protein 58476..58733 Escherichia coli E24377A 5585849 YP_001451596.1 CDS EcE24377A_E0059 NC_009790.1 58733 59263 D identified by similarity to GB:AAZ89280.1; hypothetical protein 58733..59263 Escherichia coli E24377A 5585857 YP_001451597.1 CDS EcE24377A_E0060 NC_009790.1 59528 60349 D identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein 59528..60349 Escherichia coli E24377A 5585848 YP_001451598.1 CDS EcE24377A_E0061 NC_009790.1 60352 61440 D identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 60352..61440 Escherichia coli E24377A 5585845 YP_001451599.1 CDS EcE24377A_E0063 NC_009790.1 61445 62395 D identified by match to protein family HMM PF04393; hypothetical protein 61445..62395 Escherichia coli E24377A 5585891 YP_001451600.1 CDS EcE24377A_E0062 NC_009790.1 62340 62453 R identified by glimmer; putative; hypothetical protein complement(62340..62453) Escherichia coli E24377A 5585887 YP_001451601.1 CDS EcE24377A_E0065 NC_009790.1 63467 63685 R IS630, transposase, truncation complement(63467..63685) Escherichia coli E24377A 5585819 YP_001451602.1 CDS EcE24377A_E0066 NC_009790.1 64940 65209 R IS1294, transposase, truncation complement(64940..65209) Escherichia coli E24377A 5585832 YP_001451603.1 CDS EcE24377A_E0068 NC_009790.1 65257 66795 R identified by match to protein family HMM PF03050; IS66 family transposase complement(65257..66795) Escherichia coli E24377A 5585860 YP_001451604.1 CDS EcE24377A_E0069 NC_009790.1 66845 67192 R identified by match to protein family HMM PF05717; IS66 family orf2 complement(66845..67192) Escherichia coli E24377A 5585844 YP_001451605.1 CDS EcE24377A_E0070 NC_009790.1 67189 67578 R identified by match to protein family HMM PF01527; IS66 family element complement(67189..67578) Escherichia coli E24377A 5585868 YP_001451606.1 CDS EcE24377A_E0072 NC_009790.1 67666 67791 D identified by glimmer; putative; hypothetical protein 67666..67791 Escherichia coli E24377A 5585872 YP_001451607.1 CDS EcE24377A_E0071 NC_009790.1 67684 67782 R identified by glimmer; putative; hypothetical protein complement(67684..67782) Escherichia coli E24377A 5585870 YP_001451608.1 CDS traA NC_009790.1 67898 68257 D identified by similarity to SP:P12060; match to protein family HMM PF05513; match to protein family HMM TIGR02758; type IV conjugative transfer system pilin TraA 67898..68257 Escherichia coli E24377A 5585852 YP_001451609.1 CDS traL NC_009790.1 68259 68564 D identified by similarity to SP:P12058; match to protein family HMM PF07178; match to protein family HMM TIGR02762; conjugal transfer pilus assembly protein TraL 68259..68564 Escherichia coli E24377A 5585862 YP_001451610.1 CDS traE NC_009790.1 68584 69147 D identified by similarity to SP:P12057; match to protein family HMM PF05309; match to protein family HMM TIGR02761; conjugal transfer pilus assembly protein TraE 68584..69147 Escherichia coli E24377A 5585850 YP_001451611.1 CDS EcE24377A_E0076 NC_009790.1 69460 71505 D identified by match to protein family HMM PF07057; match to protein family HMM TIGR02759; putative type IV conjugative transfer system coupling protein TraD 69460..71505 Escherichia coli E24377A 5585842 YP_001451612.1 CDS EcE24377A_E0077 NC_009790.1 71532 71915 D identified by match to protein family HMM TIGR02755; type-F conjugative transfer system pilin acetylase TraX, truncation 71532..71915 Escherichia coli E24377A 5585892 YP_001451613.1 CDS EcE24377A_A0001 NC_009791.1 1408 1503 R identified by glimmer; putative; hypothetical protein complement(1408..1503) Escherichia coli E24377A 5585895 YP_001451614.1 CDS EcE24377A_A0002 NC_009791.1 2674 2895 D identified by glimmer; putative; hypothetical protein 2674..2895 Escherichia coli E24377A 5585894 YP_001451615.1 CDS EcE24377A_A0003 NC_009791.1 2984 4549 R identified by match to protein family HMM PF03432; mobilization protein MobA complement(2984..4549) Escherichia coli E24377A 5585896 YP_001461170.1 CDS thrA NC_009801.1 336 2798 D multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 336..2798 Escherichia coli E24377A 5588161 YP_001461171.1 CDS thrB NC_009801.1 2800 3732 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 2800..3732 Escherichia coli E24377A 5589520 YP_001461172.1 CDS thrC NC_009801.1 3733 5019 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 3733..5019 Escherichia coli E24377A 5590225 YP_001461173.1 CDS EcE24377A_0004 NC_009801.1 5309 5806 R identified by glimmer; hypothetical protein complement(5309..5806) Escherichia coli E24377A 5589339 YP_001461174.1 CDS EcE24377A_0005 NC_009801.1 5789 6769 D identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 5789..6769 Escherichia coli E24377A 5588870 YP_001461175.1 CDS EcE24377A_0006 NC_009801.1 6961 7737 R identified by similarity to SP:Q8ZS17; match to protein family HMM PF03883; hypothetical protein complement(6961..7737) Escherichia coli E24377A 5589270 YP_001461176.1 CDS agcS NC_009801.1 7807 9237 R identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; amino acid carrier protein complement(7807..9237) Escherichia coli E24377A 5589335 YP_001461177.1 CDS tal2 NC_009801.1 9516 10469 D identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874; transaldolase B 9516..10469 Escherichia coli E24377A 5588812 YP_001461178.1 CDS mogA NC_009801.1 10584 11171 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 10584..11171 Escherichia coli E24377A 5589183 YP_001461179.1 CDS EcE24377A_0010 NC_009801.1 11206 11772 R identified by match to protein family HMM PF01184; hypothetical protein complement(11206..11772) Escherichia coli E24377A 5586648 YP_001461180.1 CDS EcE24377A_0011 NC_009801.1 11921 12634 R identified by match to protein family HMM PF03667; hypothetical protein complement(11921..12634) Escherichia coli E24377A 5588148 YP_001461181.1 CDS EcE24377A_0012 NC_009801.1 12660 13064 R hypothetical protein complement(12660..13064) Escherichia coli E24377A 5588138 YP_001461182.1 CDS EcE24377A_0013 NC_009801.1 13199 13348 R identified by glimmer; hypothetical protein complement(13199..13348) Escherichia coli E24377A 5589574 YP_001461183.1 CDS dnaK NC_009801.1 13441 15357 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 13441..15357 Escherichia coli E24377A 5590429 YP_001461184.1 CDS dnaJ NC_009801.1 15446 16576 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 15446..16576 Escherichia coli E24377A 5588207 YP_001461185.1 CDS nhaA NC_009801.1 17418 18584 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 17418..18584 Escherichia coli E24377A 5589884 YP_001461186.1 CDS nhaR NC_009801.1 18650 19549 D Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 18650..19549 Escherichia coli E24377A 5586221 YP_001461187.1 CDS EcE24377A_0018 NC_009801.1 19588 20547 R identified by similarity to GB:AAZ86820.1; hypothetical protein complement(19588..20547) Escherichia coli E24377A 5588977 YP_001461188.1 CDS EcE24377A_0020 NC_009801.1 22138 23460 R identified by glimmer; hypothetical protein complement(22138..23460) Escherichia coli E24377A 5588619 YP_001461189.1 CDS EcE24377A_0021 NC_009801.1 23481 23585 D identified by glimmer; hypothetical protein 23481..23585 Escherichia coli E24377A 5590352 YP_001461190.1 CDS EcE24377A_0022 NC_009801.1 23844 24008 R identified by glimmer; hypothetical protein complement(23844..24008) Escherichia coli E24377A 5588802 YP_001461191.1 CDS rpsT NC_009801.1 24030 24293 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(24030..24293) Escherichia coli E24377A 5586086 YP_001461192.1 CDS EcE24377A_0024 NC_009801.1 24396 24614 D identified by similarity to GB:AAZ86826.1; hypothetical protein 24396..24614 Escherichia coli E24377A 5590625 YP_001461193.1 CDS ribF NC_009801.1 24622 25563 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 24622..25563 Escherichia coli E24377A 5587150 YP_001461194.1 CDS ileS NC_009801.1 25606 28422 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 25606..28422 Escherichia coli E24377A 5587280 YP_001461195.1 CDS lspA NC_009801.1 28422 28916 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 28422..28916 Escherichia coli E24377A 5586401 YP_001461196.1 CDS fkpB NC_009801.1 29021 29470 D identified by match to protein family HMM PF00254; FKBP-type peptidylprolyl isomerase 29021..29470 Escherichia coli E24377A 5586012 YP_001461197.1 CDS ispH NC_009801.1 29472 30422 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 29472..30422 Escherichia coli E24377A 5589185 YP_001461198.1 CDS rihC NC_009801.1 30488 31402 D catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 30488..31402 Escherichia coli E24377A 5589098 YP_001461199.1 CDS dapB NC_009801.1 31569 32390 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 31569..32390 Escherichia coli E24377A 5585997 YP_001461200.1 CDS EcE24377A_0032 NC_009801.1 32633 32728 R hypothetical protein complement(32633..32728) Escherichia coli E24377A 5588786 YP_001461201.1 CDS carA NC_009801.1 32846 33994 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 32846..33994 Escherichia coli E24377A 5586508 YP_001461202.1 CDS carB NC_009801.1 34012 37233 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 34012..37233 Escherichia coli E24377A 5588649 YP_001461203.1 CDS EcE24377A_0035 NC_009801.1 37241 37459 R identified by glimmer; hypothetical protein complement(37241..37459) Escherichia coli E24377A 5588862 YP_001461204.1 CDS caiF NC_009801.1 37494 37889 D regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 37494..37889 Escherichia coli E24377A 5586841 YP_001461205.1 CDS caiE NC_009801.1 37975 38565 R involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE complement(37975..38565) Escherichia coli E24377A 5587319 YP_001461206.2 CDS caiD NC_009801.1 38571 39356 R catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase complement(38571..39356) Escherichia coli E24377A 5587267 YP_001461207.1 CDS caiC NC_009801.1 39465 41033 R identified by match to protein family HMM PF00501; crotonobetaine/carnitine-CoA ligase complement(39465..41033) Escherichia coli E24377A 5588976 YP_001461208.1 CDS caiB NC_009801.1 41092 42309 R catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase complement(41092..42309) Escherichia coli E24377A 5590821 YP_001461209.1 CDS caiA NC_009801.1 42438 43580 R catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase complement(42438..43580) Escherichia coli E24377A 5590267 YP_001461210.1 CDS caiT NC_009801.1 43611 45125 R catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter complement(43611..45125) Escherichia coli E24377A 5586104 YP_001461211.1 CDS EcE24377A_0043 NC_009801.1 45140 45241 D identified by glimmer; hypothetical protein 45140..45241 Escherichia coli E24377A 5586268 YP_001461212.1 CDS EcE24377A_0044 NC_009801.1 45420 45530 D identified by similarity to GB:AAX63975.1; hypothetical protein 45420..45530 Escherichia coli E24377A 5589593 YP_001461213.1 CDS etfB NC_009801.1 45599 46369 D required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 45599..46369 Escherichia coli E24377A 5589423 YP_001461214.1 CDS fixB NC_009801.1 46384 47325 D involved in electron transfer during carnitine metabolism; electron transfer flavoprotein FixB 46384..47325 Escherichia coli E24377A 5587416 YP_001461215.1 CDS fixC NC_009801.1 47376 48662 D FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 47376..48662 Escherichia coli E24377A 5586155 YP_001461216.1 CDS fixX NC_009801.1 48659 48946 D ferredoxin-like protein FixX 48659..48946 Escherichia coli E24377A 5588599 YP_001461217.1 CDS EcE24377A_0049 NC_009801.1 49004 50335 D identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator family transporter 49004..50335 Escherichia coli E24377A 5590819 YP_001461218.1 CDS kefF NC_009801.1 50443 50973 D Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 50443..50973 Escherichia coli E24377A 5589117 YP_001461219.1 CDS kefC NC_009801.1 50966 52828 D transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 50966..52828 Escherichia coli E24377A 5590837 YP_001461220.1 CDS folA NC_009801.1 53020 53499 D catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 53020..53499 Escherichia coli E24377A 5587884 YP_001461221.1 CDS apaH NC_009801.1 53577 54419 R hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase complement(53577..54419) Escherichia coli E24377A 5586714 YP_001461222.1 CDS apaG NC_009801.1 54426 54803 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(54426..54803) Escherichia coli E24377A 5587798 YP_001461223.1 CDS ksgA NC_009801.1 54806 55627 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(54806..55627) Escherichia coli E24377A 5589509 YP_001461224.1 CDS pdxA NC_009801.1 55624 56613 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(55624..56613) Escherichia coli E24377A 5586267 YP_001461225.1 CDS surA NC_009801.1 56613 57899 R Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA complement(56613..57899) Escherichia coli E24377A 5590250 YP_001461226.1 CDS imp NC_009801.1 57952 60306 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(57952..60306) Escherichia coli E24377A 5586004 YP_001461227.1 CDS djlA NC_009801.1 60561 61376 D functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 60561..61376 Escherichia coli E24377A 5587614 YP_001461228.1 CDS EcE24377A_0060 NC_009801.1 61493 62152 R catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A complement(61493..62152) Escherichia coli E24377A 5586538 YP_001461229.1 CDS rapA NC_009801.1 62164 65070 R transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA complement(62164..65070) Escherichia coli E24377A 5590175 YP_001461230.1 CDS polB NC_009801.1 65235 67586 R Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II complement(65235..67586) Escherichia coli E24377A 5590669 YP_001461231.1 CDS araD NC_009801.1 67661 68356 R catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase complement(67661..68356) Escherichia coli E24377A 5590176 YP_001461232.1 CDS araA NC_009801.1 68525 70027 R catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase complement(68525..70027) Escherichia coli E24377A 5586876 YP_001461233.1 CDS araB NC_009801.1 70038 71738 R catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase complement(70038..71738) Escherichia coli E24377A 5587106 YP_001461234.1 CDS araC NC_009801.1 72077 72955 D positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 72077..72955 Escherichia coli E24377A 5589356 YP_001461235.1 CDS EcE24377A_0067 NC_009801.1 73041 73805 D identified by similarity to SP:P30149; match to protein family HMM PF09335; hypothetical protein 73041..73805 Escherichia coli E24377A 5587008 YP_001461236.1 CDS thiQ NC_009801.1 73919 74617 R with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit complement(73919..74617) Escherichia coli E24377A 5588388 YP_001461237.1 CDS thiP NC_009801.1 74601 76211 R permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein complement(74601..76211) Escherichia coli E24377A 5590217 YP_001461238.1 CDS tbpA NC_009801.1 76187 77170 R part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit complement(76187..77170) Escherichia coli E24377A 5590754 YP_001461239.1 CDS EcE24377A_0071 NC_009801.1 77214 77333 R lipoprotein complement(77214..77333) Escherichia coli E24377A 5588848 YP_001461240.1 CDS sgrR NC_009801.1 77334 78989 R activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR complement(77334..78989) Escherichia coli E24377A 5587479 YP_001461241.1 CDS setA NC_009801.1 79311 80489 D identified by similarity to SP:P31675; match to protein family HMM PF07690; match to protein family HMM TIGR00899; major facilitator superfamily sugar transporter 79311..80489 Escherichia coli E24377A 5590260 YP_001461242.1 CDS leuD NC_009801.1 80538 81143 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(80538..81143) Escherichia coli E24377A 5588756 YP_001461243.1 CDS leuC NC_009801.1 81154 82554 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(81154..82554) Escherichia coli E24377A 5587213 YP_001461244.1 CDS leuB NC_009801.1 82557 83648 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(82557..83648) Escherichia coli E24377A 5589971 YP_001461245.1 CDS leuA NC_009801.1 83648 85219 R catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase complement(83648..85219) Escherichia coli E24377A 5590425 YP_001461246.1 CDS leuO NC_009801.1 86058 87002 D activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 86058..87002 Escherichia coli E24377A 5588252 YP_001461247.1 CDS ilvI NC_009801.1 87320 89044 D catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 87320..89044 Escherichia coli E24377A 5587843 YP_001461248.1 CDS ilvH NC_009801.1 89047 89538 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 89047..89538 Escherichia coli E24377A 5586249 YP_001461249.1 CDS EcE24377A_0081 NC_009801.1 89590 89721 D identified by glimmer; hypothetical protein 89590..89721 Escherichia coli E24377A 5586100 YP_001461250.1 CDS fruR NC_009801.1 89718 90722 D binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 89718..90722 Escherichia coli E24377A 5588519 YP_001461251.1 CDS mraZ NC_009801.1 91324 91782 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 91324..91782 Escherichia coli E24377A 5588249 YP_001461252.1 CDS mraW NC_009801.1 91784 92725 D identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 91784..92725 Escherichia coli E24377A 5588283 YP_001461253.1 CDS ftsL NC_009801.1 92722 93087 D membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 92722..93087 Escherichia coli E24377A 5586705 YP_001461254.1 CDS ftsI NC_009801.1 93103 94869 D identified by similarity to SP:P0AD68; match to protein family HMM PF00905; match to protein family HMM PF03717; peptidoglycan synthetase FtsI 93103..94869 Escherichia coli E24377A 5587071 YP_001461255.1 CDS murE NC_009801.1 94856 96343 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 94856..96343 Escherichia coli E24377A 5588782 YP_001461256.1 CDS murF NC_009801.1 96340 97698 D identified by similarity to SP:P11880; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 96340..97698 Escherichia coli E24377A 5590344 YP_001461257.1 CDS mraY NC_009801.1 97692 98774 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 97692..98774 Escherichia coli E24377A 5588595 YP_001461258.1 CDS murD NC_009801.1 98777 100093 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 98777..100093 Escherichia coli E24377A 5586940 YP_001461259.1 CDS ftsW NC_009801.1 100093 101337 D integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 100093..101337 Escherichia coli E24377A 5587083 YP_001461260.1 CDS murG NC_009801.1 101334 102401 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 101334..102401 Escherichia coli E24377A 5587512 YP_001461261.1 CDS murC NC_009801.1 102455 103930 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 102455..103930 Escherichia coli E24377A 5589461 YP_001461262.1 CDS ddl NC_009801.1 103923 104843 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 103923..104843 Escherichia coli E24377A 5589930 YP_001461263.1 CDS ftsQ NC_009801.1 104845 105675 D involved in septum formation; cell division protein FtsQ 104845..105675 Escherichia coli E24377A 5589903 YP_001461264.1 CDS ftsA NC_009801.1 105672 106934 D ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 105672..106934 Escherichia coli E24377A 5587153 YP_001461265.1 CDS ftsZ NC_009801.1 106995 108146 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 106995..108146 Escherichia coli E24377A 5589773 YP_001461266.1 CDS lpxC NC_009801.1 108247 109164 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 108247..109164 Escherichia coli E24377A 5586963 YP_001461267.1 CDS secM NC_009801.1 109320 109907 D secM translational pause allows for the initiation of secA translation; SecA regulator SecM 109320..109907 Escherichia coli E24377A 5587410 YP_001461268.1 CDS secA NC_009801.1 109969 112674 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 109969..112674 Escherichia coli E24377A 5587476 YP_001461269.1 CDS mutT NC_009801.1 112734 113123 D identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586; nucleoside triphosphate pyrophosphohydrolase 112734..113123 Escherichia coli E24377A 5587704 YP_001461270.1 CDS EcE24377A_0102 NC_009801.1 113138 113251 R identified by similarity to GB:AAZ86903.1; hypothetical protein complement(113138..113251) Escherichia coli E24377A 5588446 YP_001461271.1 CDS EcE24377A_0103 NC_009801.1 113223 113420 R identified by similarity to SP:P0A8H8; match to protein family HMM PF03884; zinc-binding protein complement(113223..113420) Escherichia coli E24377A 5587966 YP_001461272.1 CDS EcE24377A_0104 NC_009801.1 113430 114173 R identified by match to protein family HMM PF07072; hypothetical protein complement(113430..114173) Escherichia coli E24377A 5589216 YP_001461273.1 CDS coaE NC_009801.1 114173 114793 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(114173..114793) Escherichia coli E24377A 5590083 YP_001461274.1 CDS guaC NC_009801.1 115018 116061 D catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 115018..116061 Escherichia coli E24377A 5589315 YP_001461275.1 CDS hofB NC_009801.1 117288 118673 R identified by match to protein family HMM PF00437; hypothetical protein complement(117288..118673) Escherichia coli E24377A 5589870 YP_001461276.1 CDS pilA NC_009801.1 118683 119123 R identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; major pilin subunit complement(118683..119123) Escherichia coli E24377A 5590855 YP_001461277.1 CDS nadC NC_009801.1 119326 120219 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase complement(119326..120219) Escherichia coli E24377A 5585964 YP_001461278.1 CDS ampD NC_009801.1 120307 120858 D identified by similarity to SP:P13016; match to protein family HMM PF01510; N-acetyl-anhydromuranmyl-L-alanine amidase 120307..120858 Escherichia coli E24377A 5586289 YP_001461279.1 CDS ampE NC_009801.1 120855 121709 D involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 120855..121709 Escherichia coli E24377A 5589093 YP_001461280.1 CDS aroP NC_009801.1 121752 123122 R identified by similarity to SP:P15993; match to protein family HMM PF00324; aromatic amino acid transporter complement(121752..123122) Escherichia coli E24377A 5586474 YP_001461281.1 CDS pdhR NC_009801.1 123666 124430 D activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 123666..124430 Escherichia coli E24377A 5590200 YP_001461282.1 CDS aceE NC_009801.1 124591 127254 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 124591..127254 Escherichia coli E24377A 5589741 YP_001461283.1 CDS aceF NC_009801.1 127269 129161 D E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 127269..129161 Escherichia coli E24377A 5590099 YP_001461284.1 CDS lpdA NC_009801.1 129486 130910 D E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 129486..130910 Escherichia coli E24377A 5587205 YP_001461285.1 CDS EcE24377A_0119 NC_009801.1 130981 132834 R identified by similarity to GB:BAB33544.1; hypothetical protein complement(130981..132834) Escherichia coli E24377A 5589180 YP_001461286.1 CDS acnB NC_009801.1 133189 135786 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 133189..135786 Escherichia coli E24377A 5590861 YP_001461287.1 CDS EcE24377A_0121 NC_009801.1 135961 136323 D identified by similarity to SP:P59396; match to protein family HMM PF06062; hypothetical protein 135961..136323 Escherichia coli E24377A 5588282 YP_001461288.1 CDS speD NC_009801.1 136361 137155 R S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase complement(136361..137155) Escherichia coli E24377A 5589812 YP_001461289.1 CDS speE NC_009801.1 137171 138037 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(137171..138037) Escherichia coli E24377A 5588895 YP_001461290.1 CDS EcE24377A_0124 NC_009801.1 138143 138490 R hypothetical protein complement(138143..138490) Escherichia coli E24377A 5586246 YP_001461291.1 CDS cueO NC_009801.1 138617 140206 D laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 138617..140206 Escherichia coli E24377A 5588097 YP_001461292.1 CDS gcd NC_009801.1 140253 142643 R identified by similarity to SP:P15877; match to protein family HMM PF01011; match to protein family HMM TIGR03074; glucose dehydrogenase complement(140253..142643) Escherichia coli E24377A 5587261 YP_001461293.1 CDS hpt NC_009801.1 142849 143385 D identified by similarity to SP:P0A9M2; match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine phosphoribosyltransferase 142849..143385 Escherichia coli E24377A 5587457 YP_001461294.1 CDS can NC_009801.1 143426 144088 R catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase complement(143426..144088) Escherichia coli E24377A 5589571 YP_001461295.1 CDS EcE24377A_0129 NC_009801.1 144197 145123 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 144197..145123 Escherichia coli E24377A 5589095 YP_001461296.1 CDS EcE24377A_0130 NC_009801.1 145120 145890 D identified by match to protein family HMM PF01061; ABC transporter permease 145120..145890 Escherichia coli E24377A 5587405 YP_001461297.1 CDS EcE24377A_0131 NC_009801.1 145995 146435 D identified by match to protein family HMM PF03610; PTS system transporter subunit IIA 145995..146435 Escherichia coli E24377A 5588225 YP_001461298.1 CDS EcE24377A_0132 NC_009801.1 146499 147728 D identified by match to protein family HMM PF01522; polysaccharide deacetylase 146499..147728 Escherichia coli E24377A 5589341 YP_001461299.1 CDS panD NC_009801.1 147732 148112 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(147732..148112) Escherichia coli E24377A 5589361 YP_001461300.1 CDS EcE24377A_0134 NC_009801.1 148080 148274 D identified by glimmer; hypothetical protein 148080..148274 Escherichia coli E24377A 5589774 YP_001461301.1 CDS EcE24377A_0135 NC_009801.1 148386 149288 D identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein 148386..149288 Escherichia coli E24377A 5588682 YP_001461302.1 CDS panC NC_009801.1 149362 150213 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase complement(149362..150213) Escherichia coli E24377A 5590089 YP_001461303.1 CDS panB NC_009801.1 150225 151019 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(150225..151019) Escherichia coli E24377A 5590338 YP_001461304.1 CDS EcE24377A_0138 NC_009801.1 151132 152406 R identified by match to protein family HMM PF00419; fimbrial-like adhesin protein complement(151132..152406) Escherichia coli E24377A 5587036 YP_001461305.1 CDS EcE24377A_0139 NC_009801.1 152459 153055 R identified by similarity to GB:AAZ86939.1; hypothetical protein complement(152459..153055) Escherichia coli E24377A 5590847 YP_001461306.1 CDS EcE24377A_0140 NC_009801.1 153082 153684 R identified by match to protein family HMM PF00419; fimbrial protein complement(153082..153684) Escherichia coli E24377A 5588655 YP_001461307.1 CDS EcE24377A_0141 NC_009801.1 153686 153781 R identified by glimmer; hypothetical protein complement(153686..153781) Escherichia coli E24377A 5590145 YP_001461308.1 CDS EcE24377A_0142 NC_009801.1 154285 156885 R similar to the fimbrial usher protein PapC; outer membrane usher protein complement(154285..156885) Escherichia coli E24377A 5590283 YP_001461309.1 CDS EcE24377A_0143 NC_009801.1 156920 157660 R identified by match to protein family HMM PF00345; match to protein family HMM PF02753; chaperone protein EcpD complement(156920..157660) Escherichia coli E24377A 5587862 YP_001461310.1 CDS EcE24377A_0144 NC_009801.1 157640 157753 D identified by glimmer; hypothetical protein 157640..157753 Escherichia coli E24377A 5589158 YP_001461311.1 CDS EcE24377A_0145 NC_009801.1 157765 158349 R identified by similarity to SP:P08190; match to protein family HMM PF00419; fimbrial protein complement(157765..158349) Escherichia coli E24377A 5589649 YP_001461312.1 CDS folK NC_009801.1 158719 159198 R catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(158719..159198) Escherichia coli E24377A 5590014 YP_001461313.1 CDS pcnB NC_009801.1 159195 160559 R Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase complement(159195..160559) Escherichia coli E24377A 5586901 YP_001461314.1 CDS gluQ NC_009801.1 160652 161578 R this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase complement(160652..161578) Escherichia coli E24377A 5588887 YP_001461315.1 CDS dksA NC_009801.1 161615 162070 R identified by match to protein family HMM PF01258; match to protein family HMM TIGR02420; RNA polymerase-binding transcription factor complement(161615..162070) Escherichia coli E24377A 5588850 YP_001461316.1 CDS sfsA NC_009801.1 162248 162952 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(162248..162952) Escherichia coli E24377A 5588404 YP_001461317.1 CDS ligT NC_009801.1 162967 163497 R identified by match to protein family HMM PF02834; match to protein family HMM TIGR02258; 2'-5' RNA ligase complement(162967..163497) Escherichia coli E24377A 5587101 YP_001461318.1 CDS hrpB NC_009801.1 163571 166000 D similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 163571..166000 Escherichia coli E24377A 5588840 YP_001461319.1 CDS mrcB NC_009801.1 166196 168730 D bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 166196..168730 Escherichia coli E24377A 5586941 YP_001461320.1 CDS EcE24377A_0154 NC_009801.1 168795 168929 R identified by glimmer; hypothetical protein complement(168795..168929) Escherichia coli E24377A 5587133 YP_001461321.1 CDS fhuA NC_009801.1 168950 171193 D involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 168950..171193 Escherichia coli E24377A 5590762 YP_001461322.1 CDS fhuC NC_009801.1 171244 172041 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 171244..172041 Escherichia coli E24377A 5585968 YP_001461323.1 CDS fhuD NC_009801.1 172041 172931 D Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 172041..172931 Escherichia coli E24377A 5587176 YP_001461324.1 CDS fhuB NC_009801.1 172928 174910 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 172928..174910 Escherichia coli E24377A 5590271 YP_001461325.1 CDS hemL NC_009801.1 174945 176225 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(174945..176225) Escherichia coli E24377A 5589671 YP_001461326.1 CDS clcA NC_009801.1 176450 177871 D Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 176450..177871 Escherichia coli E24377A 5588754 YP_001461327.1 CDS EcE24377A_0161 NC_009801.1 177953 178297 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 177953..178297 Escherichia coli E24377A 5588551 YP_001461328.1 CDS EcE24377A_0162 NC_009801.1 178344 178967 R identified by match to protein family HMM PF03458; hypothetical protein complement(178344..178967) Escherichia coli E24377A 5589334 YP_001461329.1 CDS btuF NC_009801.1 179005 179805 R solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF complement(179005..179805) Escherichia coli E24377A 5589415 YP_001461330.1 CDS mtnN NC_009801.1 179798 180496 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(179798..180496) Escherichia coli E24377A 5590428 YP_001461331.1 CDS dgt NC_009801.1 180580 182097 D forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 180580..182097 Escherichia coli E24377A 5585949 YP_001461332.1 CDS degP NC_009801.1 182227 183651 D protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 182227..183651 Escherichia coli E24377A 5587049 YP_001461333.1 CDS cdaR NC_009801.1 183833 184963 D regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 183833..184963 Escherichia coli E24377A 5587960 YP_001461334.1 CDS EcE24377A_0168 NC_009801.1 185052 185438 R hypothetical protein complement(185052..185438) Escherichia coli E24377A 5589200 YP_001461335.1 CDS dapD NC_009801.1 185753 186577 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(185753..186577) Escherichia coli E24377A 5587337 YP_001461336.1 CDS glnD NC_009801.1 186608 189280 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase complement(186608..189280) Escherichia coli E24377A 5589363 YP_001461337.1 CDS map NC_009801.1 189342 190136 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(189342..190136) Escherichia coli E24377A 5589009 YP_001461338.1 CDS rpsB NC_009801.1 190504 191229 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 190504..191229 Escherichia coli E24377A 5589364 YP_001461339.1 CDS tsf NC_009801.1 191487 192338 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 191487..192338 Escherichia coli E24377A 5588226 YP_001461340.1 CDS pyrH NC_009801.1 192485 193210 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 192485..193210 Escherichia coli E24377A 5586966 YP_001461341.1 CDS frr NC_009801.1 193502 194059 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 193502..194059 Escherichia coli E24377A 5587023 YP_001461342.1 CDS dxr NC_009801.1 194151 195347 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 194151..195347 Escherichia coli E24377A 5587148 YP_001461343.1 CDS uppS NC_009801.1 195536 196294 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 195536..196294 Escherichia coli E24377A 5587225 YP_001461344.1 CDS cdsA NC_009801.1 196307 197164 D catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 196307..197164 Escherichia coli E24377A 5585973 YP_001461345.1 CDS rseP NC_009801.1 197176 198528 D catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 197176..198528 Escherichia coli E24377A 5588518 YP_001461346.1 CDS yaeT NC_009801.1 198558 200990 D part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 198558..200990 Escherichia coli E24377A 5586085 YP_001461347.1 CDS skp NC_009801.1 201112 201597 D identified by similarity to SP:P31519; match to protein family HMM PF03938; periplasmic chaperone 201112..201597 Escherichia coli E24377A 5589902 YP_001461348.1 CDS lpxD NC_009801.1 201601 202626 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 201601..202626 Escherichia coli E24377A 5586675 YP_001461349.1 CDS fabZ NC_009801.1 202731 203186 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 202731..203186 Escherichia coli E24377A 5590406 YP_001461350.1 CDS lpxA NC_009801.1 203190 203978 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 203190..203978 Escherichia coli E24377A 5589140 YP_001461351.1 CDS lpxB NC_009801.1 203978 205126 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 203978..205126 Escherichia coli E24377A 5590380 YP_001461352.1 CDS rnhB NC_009801.1 205123 205719 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 205123..205719 Escherichia coli E24377A 5587001 YP_001461353.1 CDS dnaE NC_009801.1 205756 209238 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 205756..209238 Escherichia coli E24377A 5586391 YP_001461354.1 CDS accA NC_009801.1 209251 210210 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 209251..210210 Escherichia coli E24377A 5590409 YP_001461355.1 CDS ldcC NC_009801.1 210309 212450 D identified by similarity to SP:P52095; match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; lysine decarboxylase, constitutive 210309..212450 Escherichia coli E24377A 5589236 YP_001461356.1 CDS EcE24377A_0191 NC_009801.1 212507 212896 D identified by match to protein family HMM PF00903; hypothetical protein 212507..212896 Escherichia coli E24377A 5586260 YP_001461357.1 CDS tilS NC_009801.1 212961 214259 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 212961..214259 Escherichia coli E24377A 5589780 YP_001461358.1 CDS rof NC_009801.1 214308 214568 R Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator complement(214308..214568) Escherichia coli E24377A 5587746 YP_001461359.1 CDS EcE24377A_0194 NC_009801.1 214555 214755 R identified by match to protein family HMM PF06786; hypothetical protein complement(214555..214755) Escherichia coli E24377A 5586428 YP_001461360.1 CDS EcE24377A_0195 NC_009801.1 214921 215466 D identified by match to protein family HMM PF07152; hypothetical protein 214921..215466 Escherichia coli E24377A 5587220 YP_001461361.1 CDS EcE24377A_0196 NC_009801.1 215463 215885 D identified by match to protein family HMM PF00472; peptidyl-tRNA hydrolase domain-containing protein 215463..215885 Escherichia coli E24377A 5588021 YP_001461362.1 CDS cutF NC_009801.1 215899 216609 D identified by match to protein family HMM PF04170; lipoprotein involved with copper homeostasis and adhesion 215899..216609 Escherichia coli E24377A 5590582 YP_001461363.1 CDS EcE24377A_0198 NC_009801.1 216859 217839 D identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 216859..217839 Escherichia coli E24377A 5588167 YP_001461364.1 CDS EcE24377A_0200 NC_009801.1 217966 218076 D identified by glimmer; hypothetical protein 217966..218076 Escherichia coli E24377A 5586009 YP_001461365.1 CDS proS NC_009801.1 218919 220637 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(218919..220637) Escherichia coli E24377A 5587814 YP_001461366.1 CDS EcE24377A_0202 NC_009801.1 220749 221456 R identified by match to protein family HMM PF01980; match to protein family HMM TIGR00104; hypothetical protein complement(220749..221456) Escherichia coli E24377A 5586773 YP_001461367.1 CDS rcsF NC_009801.1 221453 221857 R outer membrane lipoprotein complement(221453..221857) Escherichia coli E24377A 5588215 YP_001461368.1 CDS metQ NC_009801.1 221975 222790 R identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363; DL-methionine transporter substrate-binding subunit complement(221975..222790) Escherichia coli E24377A 5587140 YP_001461369.1 CDS metI NC_009801.1 222830 223483 R part of the MetNIQ methionine uptake system; DL-methionine transporter permease complement(222830..223483) Escherichia coli E24377A 5587597 YP_001461370.1 CDS metN NC_009801.1 223476 224507 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit complement(223476..224507) Escherichia coli E24377A 5588083 YP_001461371.1 CDS EcE24377A_0207 NC_009801.1 224695 225270 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 224695..225270 Escherichia coli E24377A 5590359 YP_001461372.1 CDS dkgB NC_009801.1 231166 231969 D catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 231166..231969 Escherichia coli E24377A 5589583 YP_001461373.1 CDS EcE24377A_0212 NC_009801.1 231966 232880 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(231966..232880) Escherichia coli E24377A 5588132 YP_001461374.1 CDS EcE24377A_0214 NC_009801.1 233121 233921 D identified by match to protein family HMM PF03372; hypothetical protein 233121..233921 Escherichia coli E24377A 5586303 YP_001461375.1 CDS EcE24377A_0215 NC_009801.1 233999 234769 D identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242; UbiE/COQ5 family methlytransferase 233999..234769 Escherichia coli E24377A 5589512 YP_001461376.1 CDS mltD NC_009801.1 234817 236175 R catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D complement(234817..236175) Escherichia coli E24377A 5589079 YP_001461377.1 CDS gloB NC_009801.1 236247 237002 R catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase complement(236247..237002) Escherichia coli E24377A 5587003 YP_001461378.1 CDS EcE24377A_0220 NC_009801.1 237036 237758 D identified by match to protein family HMM PF08241; methyltransferase 237036..237758 Escherichia coli E24377A 5586635 YP_001461379.1 CDS EcE24377A_0218 NC_009801.1 237199 237327 R identified by glimmer; hypothetical protein complement(237199..237327) Escherichia coli E24377A 5589198 YP_001461380.1 CDS rnhA NC_009801.1 237755 238222 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(237755..238222) Escherichia coli E24377A 5590327 YP_001461381.1 CDS dnaQ NC_009801.1 238287 239018 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 238287..239018 Escherichia coli E24377A 5586594 YP_001461382.1 CDS EcE24377A_0223 NC_009801.1 239237 239335 D identified by glimmer; hypothetical protein 239237..239335 Escherichia coli E24377A 5588354 YP_001461383.1 CDS EcE24377A_0224 NC_009801.1 239557 240342 D lipoprotein 239557..240342 Escherichia coli E24377A 5587700 YP_001461384.1 CDS EcE24377A_0225 NC_009801.1 240968 241882 R hypothetical protein complement(240968..241882) Escherichia coli E24377A 5588668 YP_001461385.1 CDS EcE24377A_0226 NC_009801.1 241926 242408 R identified by similarity to GB:CAE12300.1; match to protein family HMM PF05638; match to protein family HMM TIGR03344; hypothetical protein complement(241926..242408) Escherichia coli E24377A 5590609 YP_001461386.1 CDS EcE24377A_0227 NC_009801.1 242432 243784 R identified by match to protein family HMM PF06812; ImpA domain-containing protein complement(242432..243784) Escherichia coli E24377A 5589762 YP_001461387.1 CDS EcE24377A_0228 NC_009801.1 243795 247319 R identified by match to protein family HMM PF06744; match to protein family HMM PF06761; match to protein family HMM TIGR03348; hypothetical protein complement(243795..247319) Escherichia coli E24377A 5588746 YP_001461388.1 CDS EcE24377A_0229 NC_009801.1 247338 248750 R identified by match to protein family HMM PF06812; match to protein family HMM TIGR03362; ImpA domain-containing protein complement(247338..248750) Escherichia coli E24377A 5589705 YP_001461389.1 CDS EcE24377A_0230 NC_009801.1 248755 249498 R identified by match to protein family HMM TIGR03360; type VI secretion-associated protein complement(248755..249498) Escherichia coli E24377A 5586718 YP_001461390.1 CDS EcE24377A_0231 NC_009801.1 249495 252254 R identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03345; ATP-dependent chaperone protein ClpB complement(249495..252254) Escherichia coli E24377A 5589718 YP_001461391.1 CDS EcE24377A_0232 NC_009801.1 252263 253024 R identified by similarity to GB:AAF96029.1; match to protein family HMM TIGR03349; hypothetical protein complement(252263..253024) Escherichia coli E24377A 5586638 YP_001461392.1 CDS EcE24377A_0233 NC_009801.1 253029 254360 R identified by similarity to GB:AAM83869.1; match to protein family HMM PF05936; match to protein family HMM TIGR03353; hypothetical protein complement(253029..254360) Escherichia coli E24377A 5588035 YP_001461393.1 CDS EcE24377A_0234 NC_009801.1 254363 254887 R identified by match to protein family HMM TIGR03352; type VI secretion lipoprotein complement(254363..254887) Escherichia coli E24377A 5587635 YP_001461394.1 CDS EcE24377A_0235 NC_009801.1 254884 256164 R identified by similarity to GB:CAC92824.1; match to protein family HMM TIGR03354; hypothetical protein complement(254884..256164) Escherichia coli E24377A 5590339 YP_001461395.1 CDS EcE24377A_0236 NC_009801.1 256189 257271 R identified by similarity to GB:BAB33651.1; match to protein family HMM PF06996; match to protein family HMM TIGR03347; hypothetical protein complement(256189..257271) Escherichia coli E24377A 5588261 YP_001461396.1 CDS EcE24377A_0237 NC_009801.1 257235 259085 R identified by similarity to GB:AAZ87034.1; match to protein family HMM PF05947; match to protein family HMM TIGR03359; hypothetical protein complement(257235..259085) Escherichia coli E24377A 5587361 YP_001461397.1 CDS EcE24377A_0238 NC_009801.1 259089 259502 R identified by similarity to GB:CAG76342.1; match to protein family HMM PF04965; match to protein family HMM TIGR03357; hypothetical protein complement(259089..259502) Escherichia coli E24377A 5587623 YP_001461398.1 CDS EcE24377A_0239 NC_009801.1 259509 260984 R identified by similarity to GB:BAB33654.1; match to protein family HMM PF05943; match to protein family HMM TIGR03355; hypothetical protein complement(259509..260984) Escherichia coli E24377A 5587080 YP_001461399.1 CDS EcE24377A_0240 NC_009801.1 261035 261259 R identified by glimmer; hypothetical protein complement(261035..261259) Escherichia coli E24377A 5587554 YP_001461400.1 CDS EcE24377A_0241 NC_009801.1 261294 261794 R identified by similarity to GB:AAZ87038.1; match to protein family HMM PF05591; match to protein family HMM TIGR03358; hypothetical protein complement(261294..261794) Escherichia coli E24377A 5589240 YP_001461401.1 CDS EcE24377A_0242 NC_009801.1 262222 262365 D identified by glimmer; hypothetical protein 262222..262365 Escherichia coli E24377A 5590172 YP_001461402.1 CDS EcE24377A_0243 NC_009801.1 262492 263010 D identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344; hypothetical protein 262492..263010 Escherichia coli E24377A 5588608 YP_001461403.1 CDS EcE24377A_0244 NC_009801.1 263043 263180 D identified by glimmer; hypothetical protein 263043..263180 Escherichia coli E24377A 5589419 YP_001461404.1 CDS EcE24377A_0245 NC_009801.1 263220 265361 D identified by match to protein family HMM PF04524; match to protein family HMM PF06715; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361; ImpA family type VI secretion-associated protein 263220..265361 Escherichia coli E24377A 5589586 YP_001461405.1 CDS EcE24377A_0246 NC_009801.1 265437 269684 D identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; Rhs protein 265437..269684 Escherichia coli E24377A 5587711 YP_001461406.1 CDS EcE24377A_0247 NC_009801.1 269668 270150 D hypothetical protein 269668..270150 Escherichia coli E24377A 5587417 YP_001461407.1 CDS EcE24377A_0251 NC_009801.1 272738 273508 R identified by match to protein family HMM PF00795; hypothetical protein complement(272738..273508) Escherichia coli E24377A 5589895 YP_001461408.1 CDS EcE24377A_0252 NC_009801.1 273662 274135 D inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 273662..274135 Escherichia coli E24377A 5589606 YP_001461409.1 CDS fadE NC_009801.1 274178 276622 R functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase complement(274178..276622) Escherichia coli E24377A 5586404 YP_001461410.1 CDS gmhA NC_009801.1 276862 277440 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 276862..277440 Escherichia coli E24377A 5587536 YP_001461411.1 CDS EcE24377A_0255 NC_009801.1 277494 277586 D identified by glimmer; hypothetical protein 277494..277586 Escherichia coli E24377A 5588194 YP_001461412.1 CDS EcE24377A_0257 NC_009801.1 277646 278413 D identified by match to protein family HMM PF00310; glutamine amidotransferase 277646..278413 Escherichia coli E24377A 5588578 YP_001461413.1 CDS EcE24377A_0256 NC_009801.1 278384 279124 R identified by match to protein family HMM PF06104; hypothetical protein complement(278384..279124) Escherichia coli E24377A 5587647 YP_001461414.1 CDS EcE24377A_0258 NC_009801.1 279280 279558 R identified by match to protein family HMM PF05016; match to protein family HMM TIGR00053; match to protein family HMM TIGR02385; hypothetical protein complement(279280..279558) Escherichia coli E24377A 5587896 YP_001461415.1 CDS EcE24377A_0259 NC_009801.1 279561 279821 R identified by similarity to SP:Q47150; match to protein family HMM PF04221; match to protein family HMM TIGR02384; addiction module antitoxin complement(279561..279821) Escherichia coli E24377A 5589799 YP_001461416.1 CDS EcE24377A_0261 NC_009801.1 279971 280780 D identified by match to protein family HMM PF00877; NlpC/P60 family protein 279971..280780 Escherichia coli E24377A 5589466 YP_001461417.1 CDS EcE24377A_0260 NC_009801.1 280015 280128 R identified by glimmer; hypothetical protein complement(280015..280128) Escherichia coli E24377A 5588459 YP_001461418.1 CDS EcE24377A_0262 NC_009801.1 280837 281193 R identified by match to protein family HMM PF05534; HicB family protein complement(280837..281193) Escherichia coli E24377A 5588041 YP_001461419.1 CDS fhiA NC_009801.1 281569 283308 R identified by match to protein family HMM PF00771; protein FhiA complement(281569..283308) Escherichia coli E24377A 5590491 YP_001461420.1 CDS EcE24377A_0264 NC_009801.1 283268 284038 D identified by match to protein family HMM PF00691; hypothetical protein 283268..284038 Escherichia coli E24377A 5588947 YP_001461421.1 CDS dinB NC_009801.1 284109 285164 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 284109..285164 Escherichia coli E24377A 5588122 YP_001461422.1 CDS EcE24377A_0266 NC_009801.1 285161 285613 D identified by match to protein family HMM PF00583; hypothetical protein 285161..285613 Escherichia coli E24377A 5586883 YP_001461423.1 CDS EcE24377A_0267 NC_009801.1 285832 286998 D mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; hypothetical protein 285832..286998 Escherichia coli E24377A 5588434 YP_001461424.1 CDS prfH NC_009801.1 286995 287609 D similar to release factor 1 and 2; peptide chain release factor-like protein 286995..287609 Escherichia coli E24377A 5589004 YP_001461425.1 CDS pepD NC_009801.1 287666 289123 R identified by similarity to SP:P15288; match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893; aminoacyl-histidine dipeptidase complement(287666..289123) Escherichia coli E24377A 5590667 YP_001461426.1 CDS gpt NC_009801.1 289384 289842 D catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 289384..289842 Escherichia coli E24377A 5590037 YP_001461427.1 CDS frsA NC_009801.1 289934 291178 D forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 289934..291178 Escherichia coli E24377A 5589467 YP_001461428.1 CDS crl NC_009801.1 291236 291637 D involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 291236..291637 Escherichia coli E24377A 5586696 YP_001461429.1 CDS phoE NC_009801.1 291676 292731 R identified by similarity to SP:P02932; match to protein family HMM PF00267; match to protein family HMM TIGR03304; outer membrane phosphoporin protein E complement(291676..292731) Escherichia coli E24377A 5586653 YP_001461430.1 CDS proB NC_009801.1 293019 294122 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 293019..294122 Escherichia coli E24377A 5586824 YP_001461431.1 CDS proA NC_009801.1 294134 295387 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 294134..295387 Escherichia coli E24377A 5586837 YP_001461432.1 CDS EcE24377A_0278 NC_009801.1 295804 296661 D identified by glimmer; hypothetical protein 295804..296661 Escherichia coli E24377A 5589162 YP_001461433.1 CDS EcE24377A_0279 NC_009801.1 296783 297001 D identified by match to protein family HMM PF05930; prophage CP4-57 regulatory protein 296783..297001 Escherichia coli E24377A 5586631 YP_001461434.1 CDS EcE24377A_0280 NC_009801.1 297108 298190 D identified by glimmer; hypothetical protein 297108..298190 Escherichia coli E24377A 5590067 YP_001461435.1 CDS EcE24377A_0281 NC_009801.1 298177 298890 D identified by glimmer; hypothetical protein 298177..298890 Escherichia coli E24377A 5586741 YP_001461436.1 CDS EcE24377A_0282 NC_009801.1 299412 302654 R identified by match to protein family HMM PF00176; match to protein family HMM PF00271; SNF2 family helicase complement(299412..302654) Escherichia coli E24377A 5586826 YP_001461437.1 CDS EcE24377A_0283 NC_009801.1 302654 304357 R identified by glimmer; hypothetical protein complement(302654..304357) Escherichia coli E24377A 5590004 YP_001461438.1 CDS EcE24377A_0284 NC_009801.1 304333 305073 R identified by glimmer; hypothetical protein complement(304333..305073) Escherichia coli E24377A 5586945 YP_001461439.1 CDS EcE24377A_0285 NC_009801.1 305087 307306 R identified by glimmer; hypothetical protein complement(305087..307306) Escherichia coli E24377A 5588822 YP_001461440.1 CDS EcE24377A_0286 NC_009801.1 307639 309348 D identified by match to protein family HMM PF02384; N4/N6-methyltransferase 307639..309348 Escherichia coli E24377A 5586832 YP_001461441.1 CDS EcE24377A_0287 NC_009801.1 309338 310753 D identified by match to protein family HMM PF01420; type I restriction modification DNA specificity domain-containing protein 309338..310753 Escherichia coli E24377A 5589822 YP_001461442.1 CDS EcE24377A_0288 NC_009801.1 310746 311933 D identified by similarity to GB:CAF28525.1; hypothetical protein 310746..311933 Escherichia coli E24377A 5588530 YP_001461443.1 CDS EcE24377A_0289 NC_009801.1 311933 315067 D identified by similarity to GB:AAB70710.1; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM TIGR00348; HsdR family type I site-specific deoxyribonuclease 311933..315067 Escherichia coli E24377A 5589443 YP_001461444.1 CDS EcE24377A_0290 NC_009801.1 315244 318276 D identified by similarity to SP:P15038; match to protein family HMM PF00580; match to protein family HMM PF01396; UvrD family helicase 315244..318276 Escherichia coli E24377A 5589702 YP_001461445.1 CDS EcE24377A_0291 NC_009801.1 318276 319091 D identified by glimmer; hypothetical protein 318276..319091 Escherichia coli E24377A 5590078 YP_001461446.1 CDS EcE24377A_0292 NC_009801.1 319243 320565 R identified by match to protein family HMM PF00589; phage integrase complement(319243..320565) Escherichia coli E24377A 5587084 YP_001461447.1 CDS EcE24377A_0294 NC_009801.1 321291 322247 R identified by match to protein family HMM PF02625; xanthine dehydrogenase accessory factor complement(321291..322247) Escherichia coli E24377A 5589889 YP_001461448.1 CDS EcE24377A_0295 NC_009801.1 322257 324455 R identified by match to protein family HMM PF01315; match to protein family HMM PF02738; xanthine dehydrogenase, molybdopterin-binding subunit complement(322257..324455) Escherichia coli E24377A 5589074 YP_001461449.1 CDS EcE24377A_0296 NC_009801.1 324452 325408 R identified by match to protein family HMM PF00941; FAD binding domain-containing protein complement(324452..325408) Escherichia coli E24377A 5587550 YP_001461450.1 CDS EcE24377A_0297 NC_009801.1 325405 326094 R identified by match to protein family HMM PF00111; match to protein family HMM PF01799; match to protein family HMM TIGR01409; xanthine dehydrogenase iron-sulfur-binding subunit complement(325405..326094) Escherichia coli E24377A 5586893 YP_001461451.1 CDS EcE24377A_0298 NC_009801.1 326512 327126 D identified by match to protein family HMM PF07274; hypothetical protein 326512..327126 Escherichia coli E24377A 5587341 YP_001461452.1 CDS EcE24377A_0299 NC_009801.1 328011 328721 R hypothetical protein complement(328011..328721) Escherichia coli E24377A 5588111 YP_001461453.1 CDS EcE24377A_0300 NC_009801.1 328690 330333 R hypothetical protein complement(328690..330333) Escherichia coli E24377A 5586256 YP_001461454.1 CDS EcE24377A_0301 NC_009801.1 330323 332848 R hypothetical protein complement(330323..332848) Escherichia coli E24377A 5587889 YP_001461455.1 CDS EcE24377A_0302 NC_009801.1 332874 333542 R identified by similarity to GB:AAN78884.1; hypothetical protein complement(332874..333542) Escherichia coli E24377A 5587335 YP_001461456.1 CDS matB NC_009801.1 333600 334187 R fimbrillin MatB complement(333600..334187) Escherichia coli E24377A 5589766 YP_001461457.1 CDS matA NC_009801.1 334262 334852 R identified by match to protein family HMM PF00196; fimbrillin MatA complement(334262..334852) Escherichia coli E24377A 5588119 YP_001461458.1 CDS EcE24377A_0305 NC_009801.1 335050 335145 R identified by glimmer; hypothetical protein complement(335050..335145) Escherichia coli E24377A 5585955 YP_001461459.1 CDS rpmJ NC_009801.1 335889 336029 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 complement(335889..336029) Escherichia coli E24377A 5586687 YP_001461460.1 CDS rpmE2 NC_009801.1 336029 336295 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(336029..336295) Escherichia coli E24377A 5587708 YP_001461461.1 CDS EcE24377A_0308 NC_009801.1 336456 336548 D identified by glimmer; hypothetical protein 336456..336548 Escherichia coli E24377A 5587692 YP_001461462.1 CDS EcE24377A_0309 NC_009801.1 336656 336757 R identified by glimmer; hypothetical protein complement(336656..336757) Escherichia coli E24377A 5590779 YP_001461463.1 CDS EcE24377A_0310 NC_009801.1 336725 336838 D identified by glimmer; hypothetical protein 336725..336838 Escherichia coli E24377A 5588482 YP_001461464.1 CDS EcE24377A_0311 NC_009801.1 337864 337974 R identified by glimmer; hypothetical protein complement(337864..337974) Escherichia coli E24377A 5588687 YP_001461465.1 CDS EcE24377A_0312 NC_009801.1 337935 342125 D identified by similarity to SP:P36943; match to protein family HMM PF02369; EaeH 337935..342125 Escherichia coli E24377A 5586806 YP_001461466.1 CDS EcE24377A_0313 NC_009801.1 342246 343103 R identified by match to protein family HMM PF00165; match to protein family HMM PF06445; AraC family transcriptional regulator complement(342246..343103) Escherichia coli E24377A 5589454 YP_001461467.1 CDS EcE24377A_0314 NC_009801.1 343352 344221 D identified by match to protein family HMM PF00248; aldo/keto reductase 343352..344221 Escherichia coli E24377A 5586056 YP_001461468.1 CDS EcE24377A_0315 NC_009801.1 344381 344974 R identified by match to protein family HMM PF04224; hypothetical protein complement(344381..344974) Escherichia coli E24377A 5589599 YP_001461470.1 CDS EcE24377A_0316 NC_009801.1 344986 345222 R identified by match to protein family HMM PF07338; hypothetical protein complement(344986..345222) Escherichia coli E24377A 5587713 YP_001461471.1 CDS EcE24377A_0318 NC_009801.1 345331 346656 R Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase complement(345331..346656) Escherichia coli E24377A 5586487 YP_001461472.1 CDS EcE24377A_0319 NC_009801.1 346736 346828 D identified by glimmer; hypothetical protein 346736..346828 Escherichia coli E24377A 5590796 YP_001461473.1 CDS EcE24377A_0320 NC_009801.1 346882 347736 D identified by match to protein family HMM PF00165; AraC family transcriptional regulator 346882..347736 Escherichia coli E24377A 5588078 YP_001461474.1 CDS EcE24377A_0321 NC_009801.1 348263 348982 D identified by match to protein family HMM PF02754; hypothetical protein 348263..348982 Escherichia coli E24377A 5586443 YP_001461475.1 CDS EcE24377A_0322 NC_009801.1 348993 350420 D identified by match to protein family HMM PF02589; match to protein family HMM TIGR00273; iron-sulfur cluster binding protein 348993..350420 Escherichia coli E24377A 5588031 YP_001461476.1 CDS EcE24377A_0323 NC_009801.1 350413 351108 D identified by similarity to GB:AAP15803.1; match to protein family HMM PF02589; hypothetical protein 350413..351108 Escherichia coli E24377A 5589538 YP_001461477.1 CDS EcE24377A_0324 NC_009801.1 351182 351379 R identified by glimmer; hypothetical protein complement(351182..351379) Escherichia coli E24377A 5590524 YP_001461478.1 CDS EcE24377A_0325 NC_009801.1 351351 352019 R identified by similarity to GB:CAD02590.1; hypothetical protein complement(351351..352019) Escherichia coli E24377A 5588957 YP_001461479.1 CDS betA NC_009801.1 352232 353902 R catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase complement(352232..353902) Escherichia coli E24377A 5585938 YP_001461480.1 CDS betB NC_009801.1 353916 355388 R catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase complement(353916..355388) Escherichia coli E24377A 5588779 YP_001461481.1 CDS betI NC_009801.1 355402 355989 R HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI complement(355402..355989) Escherichia coli E24377A 5587070 YP_001461482.1 CDS EcE24377A_0329 NC_009801.1 356127 356402 D identified by match to protein family HMM PF03811; IS1, transposase orfA 356127..356402 Escherichia coli E24377A 5588921 YP_001461483.1 CDS EcE24377A_0330 NC_009801.1 356321 356824 D identified by match to protein family HMM PF03400; IS1, transposase orfB 356321..356824 Escherichia coli E24377A 5587092 YP_001461484.1 CDS betT NC_009801.1 356894 358927 D proton-motive-force-driven choline transporter; choline transport protein BetT 356894..358927 Escherichia coli E24377A 5587428 YP_001461485.1 CDS EcE24377A_0332 NC_009801.1 359500 363483 D identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR03304; outer membrane autotransporter 359500..363483 Escherichia coli E24377A 5589482 YP_001461486.1 CDS EcE24377A_0333 NC_009801.1 363625 364713 D identified by match to protein family HMM PF00196; match to protein family HMM PF00563; LuxR family transcriptional regulator 363625..364713 Escherichia coli E24377A 5589608 YP_001461487.1 CDS EcE24377A_0334 NC_009801.1 364755 365687 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(364755..365687) Escherichia coli E24377A 5586734 YP_001461488.1 CDS EcE24377A_0335 NC_009801.1 365779 366276 R identified by similarity to SP:P77219; match to protein family HMM PF06496; hypothetical protein complement(365779..366276) Escherichia coli E24377A 5587773 YP_001461489.1 CDS EcE24377A_0336 NC_009801.1 366353 366586 D identified by similarity to GB:AAN78919.1; hypothetical protein 366353..366586 Escherichia coli E24377A 5586797 YP_001461490.1 CDS EcE24377A_0337 NC_009801.1 366534 367139 D identified by match to protein family HMM PF00023; ankyrin repeat-containing protein 366534..367139 Escherichia coli E24377A 5589653 YP_001461491.1 CDS EcE24377A_0338 NC_009801.1 367179 368042 D identified by similarity to GB:AAZ87092.1; hypothetical protein 367179..368042 Escherichia coli E24377A 5587514 YP_001461492.1 CDS EcE24377A_0339 NC_009801.1 368032 369579 D identified by match to protein family HMM PF06263; acyl-CoA synthetase 368032..369579 Escherichia coli E24377A 5589184 YP_001461493.1 CDS EcE24377A_0340 NC_009801.1 369579 370997 D identified by match to protein family HMM PF06545; hypothetical protein 369579..370997 Escherichia coli E24377A 5587584 YP_001461494.1 CDS EcE24377A_0341 NC_009801.1 371140 372090 D yahI; identified by match to protein family HMM PF00696; carbamate kinase 371140..372090 Escherichia coli E24377A 5588053 YP_001461495.1 CDS EcE24377A_0342 NC_009801.1 372238 373482 D metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; deaminase 372238..373482 Escherichia coli E24377A 5587877 YP_001461496.1 CDS EcE24377A_0343 NC_009801.1 373751 374191 D identified by match to protein family HMM PF06171; hypothetical protein 373751..374191 Escherichia coli E24377A 5589221 YP_001461497.1 CDS EcE24377A_0344 NC_009801.1 374219 374320 R identified by glimmer; hypothetical protein complement(374219..374320) Escherichia coli E24377A 5589017 YP_001461498.1 CDS EcE24377A_0345 NC_009801.1 374445 375428 D sugar ABC transporter periplasmic sugar-binding protein 374445..375428 Escherichia coli E24377A 5586125 YP_001461499.1 CDS EcE24377A_0346 NC_009801.1 375477 376961 D identified by match to protein family HMM PF00005; sugar ABC transporter ATP-binding protein 375477..376961 Escherichia coli E24377A 5586408 YP_001461500.1 CDS EcE24377A_0347 NC_009801.1 376954 377925 D identified by match to protein family HMM PF02653; sugar ABC transporter permease 376954..377925 Escherichia coli E24377A 5589893 YP_001461501.1 CDS EcE24377A_0348 NC_009801.1 377922 378878 D identified by match to protein family HMM PF02653; sugar ABC transporter permease 377922..378878 Escherichia coli E24377A 5589544 YP_001461502.1 CDS EcE24377A_0349 NC_009801.1 378965 380014 D identified by match to protein family HMM PF00107; match to protein family HMM PF08240; zinc-binding dehydrogenase oxidoreductase 378965..380014 Escherichia coli E24377A 5585944 YP_001461503.1 CDS EcE24377A_0350 NC_009801.1 380257 381072 D identified by similarity to GB:AAZ87085.1; hypothetical protein 380257..381072 Escherichia coli E24377A 5588763 YP_001461504.1 CDS EcE24377A_0352 NC_009801.1 381746 382393 R yahN; identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949; homoserine/threonine efflux protein complement(381746..382393) Escherichia coli E24377A 5586551 YP_001461505.1 CDS EcE24377A_0353 NC_009801.1 382564 382839 D identified by match to protein family HMM PF07338; hypothetical protein 382564..382839 Escherichia coli E24377A 5586129 YP_001461506.1 CDS prpR NC_009801.1 382937 384523 R identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF06506; match to protein family HMM TIGR02329; propionate catabolism operon regulatory protein PrpR complement(382937..384523) Escherichia coli E24377A 5587781 YP_001461507.1 CDS EcE24377A_0355 NC_009801.1 384584 384682 D identified by glimmer; hypothetical protein 384584..384682 Escherichia coli E24377A 5586247 YP_001461508.1 CDS prpB NC_009801.1 384761 385651 D catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 384761..385651 Escherichia coli E24377A 5586993 YP_001461509.1 CDS prpC NC_009801.1 385696 386865 D catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 385696..386865 Escherichia coli E24377A 5589480 YP_001461510.1 CDS prpD NC_009801.1 386899 388350 D functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 386899..388350 Escherichia coli E24377A 5589012 YP_001461511.1 CDS prpE NC_009801.1 388390 390276 D catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 388390..390276 Escherichia coli E24377A 5587777 YP_001461512.1 CDS codB NC_009801.1 390513 391772 D identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800; cytosine permease 390513..391772 Escherichia coli E24377A 5589477 YP_001461513.1 CDS codA NC_009801.1 391762 393045 D Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 391762..393045 Escherichia coli E24377A 5588598 YP_001461514.1 CDS cynR NC_009801.1 393085 393984 R controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source; DNA-binding transcriptional regulator CynR complement(393085..393984) Escherichia coli E24377A 5590826 YP_001461515.1 CDS EcE24377A_0363 NC_009801.1 393907 394002 D identified by glimmer; hypothetical protein 393907..394002 Escherichia coli E24377A 5587309 YP_001461516.1 CDS cynT NC_009801.1 394094 394753 D identified by match to protein family HMM PF00484; carbonic anhydrase 394094..394753 Escherichia coli E24377A 5585900 YP_001461517.1 CDS cynS NC_009801.1 394784 395254 D catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase 394784..395254 Escherichia coli E24377A 5588730 YP_001461518.1 CDS cynX NC_009801.1 395287 396441 D MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential; cyanate transporter 395287..396441 Escherichia coli E24377A 5587185 YP_001461519.1 CDS lacY NC_009801.1 396520 397773 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(396520..397773) Escherichia coli E24377A 5588591 YP_001461520.1 CDS lacZ NC_009801.1 397825 400899 R forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase complement(397825..400899) Escherichia coli E24377A 5589745 YP_001461521.1 CDS lacI NC_009801.1 401022 402113 R transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor complement(401022..402113) Escherichia coli E24377A 5588695 YP_001461522.1 CDS mhpR NC_009801.1 402181 403128 R activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional activator MhpR complement(402181..403128) Escherichia coli E24377A 5588644 YP_001461523.1 CDS mhpA NC_009801.1 403205 404869 D catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase 403205..404869 Escherichia coli E24377A 5589374 YP_001461524.1 CDS mhpB NC_009801.1 404871 405815 D catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase; 3-(2,3-dihydroxyphenyl)propionate dioxygenase 404871..405815 Escherichia coli E24377A 5589309 YP_001461525.1 CDS mhpC NC_009801.1 405818 406699 D identified by similarity to SP:P77044; match to protein family HMM PF00561; 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase 405818..406699 Escherichia coli E24377A 5590082 YP_001461526.1 CDS mhpD NC_009801.1 406709 407518 D catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid; 2-keto-4-pentenoate hydratase 406709..407518 Escherichia coli E24377A 5587540 YP_001461527.1 CDS mhpF NC_009801.1 407515 408465 D catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase 407515..408465 Escherichia coli E24377A 5586084 YP_001461528.1 CDS mhpE NC_009801.1 408462 409475 D catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 408462..409475 Escherichia coli E24377A 5587752 YP_001461529.1 CDS EcE24377A_0377 NC_009801.1 409651 410862 D identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00895; 3-hydroxyphenylpropionic transporter MhpT 409651..410862 Escherichia coli E24377A 5587560 YP_001461530.1 CDS EcE24377A_0378 NC_009801.1 410964 411503 D hypothetical protein 410964..411503 Escherichia coli E24377A 5590242 YP_001461531.1 CDS EcE24377A_0379 NC_009801.1 411525 411632 D identified by glimmer; hypothetical protein 411525..411632 Escherichia coli E24377A 5589137 YP_001461532.1 CDS fghA1 NC_009801.1 411729 412562 R identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821; S-formylglutathione hydrolase complement(411729..412562) Escherichia coli E24377A 5587379 YP_001461533.1 CDS EcE24377A_0381 NC_009801.1 412655 413764 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818; alcohol dehydrogenase complement(412655..413764) Escherichia coli E24377A 5590872 YP_001461534.1 CDS EcE24377A_0382 NC_009801.1 413799 414074 R formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR complement(413799..414074) Escherichia coli E24377A 5587587 YP_001461535.1 CDS EcE24377A_0383 NC_009801.1 414260 415033 R yaiO; identified by glimmer; hypothetical protein complement(414260..415033) Escherichia coli E24377A 5587034 YP_001461536.1 CDS EcE24377A_0384 NC_009801.1 415035 415475 R identified by match to protein family HMM PF00132; acyltransferase complement(415035..415475) Escherichia coli E24377A 5586266 YP_001461537.1 CDS EcE24377A_0385 NC_009801.1 415594 416790 R yaiP; identified by match to protein family HMM PF00535; glycosyl transferase family protein complement(415594..416790) Escherichia coli E24377A 5588509 YP_001461538.1 CDS EcE24377A_0386 NC_009801.1 416800 417471 R yaiS; identified by match to protein family HMM PF02585; GlcNAc-PI de-N-acetylase complement(416800..417471) Escherichia coli E24377A 5587589 YP_001461539.1 CDS EcE24377A_0387 NC_009801.1 417643 417750 D identified by glimmer; hypothetical protein 417643..417750 Escherichia coli E24377A 5590610 YP_001461540.1 CDS EcE24377A_0388 NC_009801.1 417909 418133 R identified by glimmer; hypothetical protein complement(417909..418133) Escherichia coli E24377A 5589304 YP_001461541.1 CDS tauA NC_009801.1 418087 419049 D with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 418087..419049 Escherichia coli E24377A 5586558 YP_001461542.1 CDS tauC NC_009801.1 419825 420652 D identified by match to protein family HMM PF00528; taurine transporter subunit 419825..420652 Escherichia coli E24377A 5586630 YP_001461543.1 CDS tauD NC_009801.1 420649 421500 D catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 420649..421500 Escherichia coli E24377A 5588471 YP_001461544.1 CDS hemB NC_009801.1 421658 422632 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(421658..422632) Escherichia coli E24377A 5586710 YP_001461545.1 CDS EcE24377A_0394 NC_009801.1 423338 424243 R IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD complement(423338..424243) Escherichia coli E24377A 5589325 YP_001461546.1 CDS EcE24377A_0395 NC_009801.1 424201 424566 R IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein complement(424201..424566) Escherichia coli E24377A 5588506 YP_001461547.1 CDS EcE24377A_0396 NC_009801.1 424630 427398 D identified by match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR03304; outer membrane autotransporter 424630..427398 Escherichia coli E24377A 5589161 YP_001461548.1 CDS EcE24377A_0397 NC_009801.1 427486 428109 D identified by similarity to SP:P0AAP5; DNA-binding transcriptional regulator 427486..428109 Escherichia coli E24377A 5587377 YP_001461549.1 CDS ampH NC_009801.1 428110 429267 R this protein has no known enzymatic function; beta-lactam binding protein AmpH complement(428110..429267) Escherichia coli E24377A 5590812 YP_001461550.1 CDS EcE24377A_0399 NC_009801.1 429313 429414 R identified by glimmer; hypothetical protein complement(429313..429414) Escherichia coli E24377A 5587833 YP_001461551.1 CDS EcE24377A_0400 NC_009801.1 429405 429599 D identified by glimmer; hypothetical protein 429405..429599 Escherichia coli E24377A 5590081 YP_001461552.1 CDS smbA NC_009801.1 429619 430839 D in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 429619..430839 Escherichia coli E24377A 5590494 YP_001461553.1 CDS EcE24377A_0402 NC_009801.1 430852 431946 D identified by match to protein family HMM PF07759; lipoprotein 430852..431946 Escherichia coli E24377A 5589316 YP_001461554.1 CDS EcE24377A_0403 NC_009801.1 431947 432051 R identified by glimmer; hypothetical protein complement(431947..432051) Escherichia coli E24377A 5589474 YP_001461555.1 CDS EcE24377A_0404 NC_009801.1 432005 432313 R identified by similarity to SP:P0AAP7; hypothetical protein complement(432005..432313) Escherichia coli E24377A 5588208 YP_001461556.1 CDS EcE24377A_0405 NC_009801.1 432441 432785 D identified by similarity to GB:AAZ87131.1; hypothetical protein 432441..432785 Escherichia coli E24377A 5587268 YP_001461557.1 CDS ddl NC_009801.1 432809 433903 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(432809..433903) Escherichia coli E24377A 5587949 YP_001461558.1 CDS EcE24377A_0407 NC_009801.1 433984 434184 D identified by glimmer; hypothetical protein 433984..434184 Escherichia coli E24377A 5589987 YP_001461559.1 CDS EcE24377A_0408 NC_009801.1 434207 434320 D identified by glimmer; hypothetical protein 434207..434320 Escherichia coli E24377A 5588651 YP_001461560.1 CDS EcE24377A_0409 NC_009801.1 434366 434626 D hypothetical protein 434366..434626 Escherichia coli E24377A 5587333 YP_001461561.1 CDS phoA NC_009801.1 434727 436142 D identified by similarity to SP:P00634; match to protein family HMM PF00245; alkaline phosphatase 434727..436142 Escherichia coli E24377A 5590008 YP_001461562.1 CDS psiF NC_009801.1 436261 436581 D identified by match to protein family HMM PF07769; hypothetical protein 436261..436581 Escherichia coli E24377A 5589113 YP_001461563.1 CDS adrA NC_009801.1 436683 437798 D catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 436683..437798 Escherichia coli E24377A 5585979 YP_001461564.1 CDS proC NC_009801.1 437815 438624 R catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase complement(437815..438624) Escherichia coli E24377A 5588373 YP_001461565.1 CDS EcE24377A_0414 NC_009801.1 438744 439202 D identified by similarity to SP:Q3Z523; match to protein family HMM PF02639; hypothetical protein 438744..439202 Escherichia coli E24377A 5590534 YP_001461566.1 CDS aroL NC_009801.1 439385 439909 D type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 439385..439909 Escherichia coli E24377A 5589344 YP_001461567.1 CDS EcE24377A_0416 NC_009801.1 439959 440150 D hypothetical protein 439959..440150 Escherichia coli E24377A 5590701 YP_001461568.1 CDS aroM NC_009801.1 440408 441085 D identified by match to protein family HMM PF07302; hypothetical protein 440408..441085 Escherichia coli E24377A 5588502 YP_001461569.1 CDS EcE24377A_0418 NC_009801.1 441157 441441 D identified by match to protein family HMM PF06865; hypothetical protein 441157..441441 Escherichia coli E24377A 5588992 YP_001461570.1 CDS EcE24377A_0419 NC_009801.1 441649 441930 D ykiA; identified by glimmer; hypothetical protein 441649..441930 Escherichia coli E24377A 5590383 YP_001461571.1 CDS rdgC NC_009801.1 442088 442999 R Required for efficient pilin antigenic variation; recombination associated protein complement(442088..442999) Escherichia coli E24377A 5588613 YP_001461572.1 CDS mak NC_009801.1 443124 444032 D catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 443124..444032 Escherichia coli E24377A 5590169 YP_001461573.1 CDS EcE24377A_0422 NC_009801.1 444011 444151 D identified by glimmer; hypothetical protein 444011..444151 Escherichia coli E24377A 5590361 YP_001461574.1 CDS araJ NC_009801.1 444175 445443 R member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ complement(444175..445443) Escherichia coli E24377A 5590114 YP_001461575.1 CDS sbcC NC_009801.1 445485 448628 R with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease SbcC complement(445485..448628) Escherichia coli E24377A 5590405 YP_001461576.1 CDS sbcD NC_009801.1 448625 449827 R with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease SbcD complement(448625..449827) Escherichia coli E24377A 5586171 YP_001461577.1 CDS EcE24377A_0426 NC_009801.1 449813 449944 D identified by glimmer; hypothetical protein 449813..449944 Escherichia coli E24377A 5587783 YP_001461578.1 CDS phoB NC_009801.1 450017 450706 D two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 450017..450706 Escherichia coli E24377A 5589223 YP_001461579.1 CDS phoR NC_009801.1 450764 452059 D membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 450764..452059 Escherichia coli E24377A 5586229 YP_001461580.1 CDS EcE24377A_0429 NC_009801.1 452070 452180 R identified by glimmer; hypothetical protein complement(452070..452180) Escherichia coli E24377A 5590209 YP_001461581.1 CDS EcE24377A_0430 NC_009801.1 452272 452421 R identified by similarity to GB:AAX64346.1; hypothetical protein complement(452272..452421) Escherichia coli E24377A 5587171 YP_001461582.1 CDS brnQ NC_009801.1 452466 453785 D identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 452466..453785 Escherichia coli E24377A 5588485 YP_001461583.1 CDS proY NC_009801.1 453861 455234 D cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; proline-specific permease 453861..455234 Escherichia coli E24377A 5589530 YP_001461584.1 CDS malZ NC_009801.1 455390 457207 D identified by similarity to SP:P21517; match to protein family HMM PF00128; maltodextrin glucosidase 455390..457207 Escherichia coli E24377A 5588632 YP_001461585.1 CDS acpH NC_009801.1 457212 457793 R Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; ACP phosphodieterase complement(457212..457793) Escherichia coli E24377A 5590041 YP_001461586.1 CDS queA NC_009801.1 457886 458956 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 457886..458956 Escherichia coli E24377A 5586128 YP_001461587.1 CDS tgt NC_009801.1 459012 460139 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 459012..460139 Escherichia coli E24377A 5586334 YP_001461588.1 CDS yajC NC_009801.1 460162 460494 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 460162..460494 Escherichia coli E24377A 5588231 YP_001461589.1 CDS secD NC_009801.1 460522 462369 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 460522..462369 Escherichia coli E24377A 5589957 YP_001461590.1 CDS secF NC_009801.1 462380 463351 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 462380..463351 Escherichia coli E24377A 5589142 YP_001461591.1 CDS EcE24377A_0440 NC_009801.1 463480 463827 D identified by match to protein family HMM PF01844; hypothetical protein 463480..463827 Escherichia coli E24377A 5588070 YP_001461592.1 CDS EcE24377A_0441 NC_009801.1 463841 463963 D identified by similarity to GB:ABB67500.1; hypothetical protein 463841..463963 Escherichia coli E24377A 5586954 YP_001461593.1 CDS tsx NC_009801.1 464004 464888 R identified by match to protein family HMM PF03502; nucleoside-specific channel-forming protein complement(464004..464888) Escherichia coli E24377A 5587483 YP_001461594.1 CDS EcE24377A_0443 NC_009801.1 465187 465726 R hypothetical protein complement(465187..465726) Escherichia coli E24377A 5586766 YP_001461595.1 CDS nrdR NC_009801.1 465877 466326 D identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244; transcriptional regulator NrdR 465877..466326 Escherichia coli E24377A 5588868 YP_001461596.1 CDS ribD NC_009801.1 466330 467433 D riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 466330..467433 Escherichia coli E24377A 5589523 YP_001461597.1 CDS ribH NC_009801.1 467522 467992 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 467522..467992 Escherichia coli E24377A 5590168 YP_001461598.1 CDS nusB NC_009801.1 468012 468431 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 468012..468431 Escherichia coli E24377A 5586262 YP_001461599.1 CDS thiL NC_009801.1 468509 469486 D catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 468509..469486 Escherichia coli E24377A 5586076 YP_001461600.1 CDS pgpA NC_009801.1 469464 469982 D hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 469464..469982 Escherichia coli E24377A 5589979 YP_001461601.1 CDS EcE24377A_0450 NC_009801.1 470036 471010 R identified by match to protein family HMM PF00248; aldo/keto reductase complement(470036..471010) Escherichia coli E24377A 5588172 YP_001461602.1 CDS dxs NC_009801.1 471190 473052 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(471190..473052) Escherichia coli E24377A 5590521 YP_001461603.1 CDS ispA NC_009801.1 473077 473976 R identified by similarity to SP:P22939; match to protein family HMM PF00348; geranyltranstransferase complement(473077..473976) Escherichia coli E24377A 5586364 YP_001461604.1 CDS xseB NC_009801.1 473976 474218 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(473976..474218) Escherichia coli E24377A 5588325 YP_001461605.1 CDS EcE24377A_0454 NC_009801.1 474306 474398 D identified by glimmer; hypothetical protein 474306..474398 Escherichia coli E24377A 5589650 YP_001461606.1 CDS thiI NC_009801.1 474424 475872 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 474424..475872 Escherichia coli E24377A 5587958 YP_001461607.1 CDS thiJ NC_009801.1 475926 476516 R identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383; DJ-1 family protein complement(475926..476516) Escherichia coli E24377A 5590685 YP_001461608.1 CDS panE NC_009801.1 476479 477390 R ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase complement(476479..477390) Escherichia coli E24377A 5585898 YP_001461609.1 CDS EcE24377A_0458 NC_009801.1 477558 478049 D nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 477558..478049 Escherichia coli E24377A 5590745 YP_001461610.1 CDS EcE24377A_0459 NC_009801.1 478177 479541 R identified by match to protein family HMM PF07690; major facilitator transporter complement(478177..479541) Escherichia coli E24377A 5589026 YP_001461611.1 CDS EcE24377A_0460 NC_009801.1 479889 480884 D identified by match to protein family HMM PF08238; hypothetical protein 479889..480884 Escherichia coli E24377A 5588697 YP_001461612.1 CDS EcE24377A_0461 NC_009801.1 480940 481482 R identified by match to protein family HMM PF00583; acetyltransferase complement(480940..481482) Escherichia coli E24377A 5589281 YP_001461613.1 CDS EcE24377A_0462 NC_009801.1 481466 481825 R identified by similarity to GB:AAZ87186.1; match to protein family HMM PF08681; hypothetical protein complement(481466..481825) Escherichia coli E24377A 5587656 YP_001461614.1 CDS cyoE NC_009801.1 481962 482852 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(481962..482852) Escherichia coli E24377A 5587317 YP_001461615.1 CDS cyoD NC_009801.1 482864 483193 R identified by similarity to SP:P0ABJ6; match to protein family HMM PF03626; match to protein family HMM TIGR02847; cytochrome o ubiquinol oxidase subunit IV complement(482864..483193) Escherichia coli E24377A 5587968 YP_001461616.1 CDS cyoC NC_009801.1 483193 483807 R identified by similarity to SP:P0ABJ3; match to protein family HMM PF00510; match to protein family HMM TIGR02842; cytochrome o ubiquinol oxidase subunit III complement(483193..483807) Escherichia coli E24377A 5589290 YP_001461617.1 CDS cyoB NC_009801.1 483797 485788 R identified by match to protein family HMM PF00115; match to protein family HMM TIGR02843; cytochrome o ubiquinol oxidase subunit I complement(483797..485788) Escherichia coli E24377A 5589343 YP_001461618.1 CDS cyoA NC_009801.1 485810 486757 R identified by similarity to SP:P0ABJ1; match to protein family HMM PF00116; match to protein family HMM PF06481; match to protein family HMM TIGR01433; cytochrome o ubiquinol oxidase subunit II complement(485810..486757) Escherichia coli E24377A 5588825 YP_001461619.1 CDS ampG NC_009801.1 487218 488693 R in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter complement(487218..488693) Escherichia coli E24377A 5588646 YP_001461620.1 CDS EcE24377A_0469 NC_009801.1 488737 489315 R identified by match to protein family HMM PF03923; hypothetical protein complement(488737..489315) Escherichia coli E24377A 5590051 YP_001461621.1 CDS EcE24377A_0470 NC_009801.1 489620 489937 D positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 489620..489937 Escherichia coli E24377A 5590556 YP_001461622.1 CDS EcE24377A_0471 NC_009801.1 489946 490134 D identified by glimmer; hypothetical protein 489946..490134 Escherichia coli E24377A 5590036 YP_001461623.1 CDS tig NC_009801.1 490281 491579 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 490281..491579 Escherichia coli E24377A 5587741 YP_001461624.1 CDS clpP NC_009801.1 491825 492448 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 491825..492448 Escherichia coli E24377A 5588301 YP_001461625.1 CDS clpX NC_009801.1 492574 493848 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 492574..493848 Escherichia coli E24377A 5587882 YP_001461626.1 CDS lon NC_009801.1 494036 496390 D identified by match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR00763; DNA-binding ATP-dependent protease La 494036..496390 Escherichia coli E24377A 5586073 YP_001461627.1 CDS hupB NC_009801.1 496599 496871 D histone-like DNA-binding protein; transcriptional regulator HU subunit beta 496599..496871 Escherichia coli E24377A 5587651 YP_001461628.1 CDS ppiD NC_009801.1 497063 498934 D identified by similarity to SP:P0ADY1; match to protein family HMM PF00639; match to protein family HMM PF09312; peptidyl-prolyl cis-trans isomerase 497063..498934 Escherichia coli E24377A 5589853 YP_001461629.1 CDS EcE24377A_0478 NC_009801.1 499085 499456 D identified by match to protein family HMM TIGR00426; competence protein ComEA 499085..499456 Escherichia coli E24377A 5587687 YP_001461630.1 CDS EcE24377A_0479 NC_009801.1 499550 499948 D identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051; thioesterase 499550..499948 Escherichia coli E24377A 5590683 YP_001461631.1 CDS queC NC_009801.1 500000 500695 R YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC complement(500000..500695) Escherichia coli E24377A 5587100 YP_001461632.1 CDS EcE24377A_0481 NC_009801.1 500760 502460 R identified by match to protein family HMM PF00496; solute-binding family 5 protein complement(500760..502460) Escherichia coli E24377A 5586781 YP_001461633.1 CDS cof NC_009801.1 502560 503378 D identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; hydrolase Cof 502560..503378 Escherichia coli E24377A 5590290 YP_001461634.1 CDS EcE24377A_0483 NC_009801.1 503531 503989 D identified by match to protein family HMM PF01037; AsnC family transcriptional regulator 503531..503989 Escherichia coli E24377A 5590438 YP_001461635.1 CDS mdlA NC_009801.1 504019 505791 D identified by match to protein family HMM PF00005; match to protein family HMM PF00664; multidrug transporter membrane\ATP-binding components 504019..505791 Escherichia coli E24377A 5588826 YP_001461636.1 CDS mdlB NC_009801.1 505784 507565 D identified by similarity to SP:P0AAG5; match to protein family HMM PF00005; match to protein family HMM PF00664; multidrug transporter membrane\ATP-binding components 505784..507565 Escherichia coli E24377A 5590331 YP_001461637.1 CDS glnK NC_009801.1 507746 508084 D indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 507746..508084 Escherichia coli E24377A 5587971 YP_001461638.1 CDS amt NC_009801.1 508114 509400 D identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836; ammonium transporter 508114..509400 Escherichia coli E24377A 5588328 YP_001461639.1 CDS tesB NC_009801.1 509448 510308 R identified by match to protein family HMM PF02551; match to protein family HMM TIGR00189; acyl-CoA thioesterase complement(509448..510308) Escherichia coli E24377A 5590692 YP_001461640.1 CDS EcE24377A_0489 NC_009801.1 510526 511098 D lipoprotein 510526..511098 Escherichia coli E24377A 5589457 YP_001461641.1 CDS EcE24377A_0490 NC_009801.1 511129 511518 R identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589; methylated-DNA-[protein]-cysteine S-methyltransferase complement(511129..511518) Escherichia coli E24377A 5588406 YP_001461642.1 CDS EcE24377A_0491 NC_009801.1 511819 512172 D identified by match to protein family HMM PF07237; hypothetical protein 511819..512172 Escherichia coli E24377A 5590148 YP_001461643.1 CDS EcE24377A_0492 NC_009801.1 512214 513770 R identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase domain-containing protein complement(512214..513770) Escherichia coli E24377A 5589942 YP_001461644.1 CDS EcE24377A_0493 NC_009801.1 513928 514437 R hypothetical protein complement(513928..514437) Escherichia coli E24377A 5588935 YP_001461645.1 CDS maa NC_009801.1 514514 515065 R identified by similarity to SP:P77791; match to protein family HMM PF00132; maltose O-acetyltransferase complement(514514..515065) Escherichia coli E24377A 5590241 YP_001461646.1 CDS EcE24377A_0495 NC_009801.1 515481 515855 R identified by similarity to GB:ABB65073.1; hypothetical protein complement(515481..515855) Escherichia coli E24377A 5586972 YP_001461647.1 CDS EcE24377A_0496 NC_009801.1 516401 519550 R identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; acriflavine resistance protein B complement(516401..519550) Escherichia coli E24377A 5588984 YP_001461648.1 CDS acrA NC_009801.1 519573 520766 R identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; acriflavine resistance protein A complement(519573..520766) Escherichia coli E24377A 5587606 YP_001461649.1 CDS acrR NC_009801.1 520908 521555 D regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 520908..521555 Escherichia coli E24377A 5586126 YP_001461650.1 CDS EcE24377A_0499 NC_009801.1 521637 521801 D identified by glimmer; hypothetical protein 521637..521801 Escherichia coli E24377A 5590251 YP_001461651.1 CDS kefA NC_009801.1 521683 525045 D small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 521683..525045 Escherichia coli E24377A 5588359 YP_001461652.1 CDS EcE24377A_0501 NC_009801.1 525091 525240 D identified by glimmer; hypothetical protein 525091..525240 Escherichia coli E24377A 5590787 YP_001461653.1 CDS EcE24377A_0502 NC_009801.1 525257 525418 R identified by similarity to RF:NP_455077.1; hypothetical protein complement(525257..525418) Escherichia coli E24377A 5589395 YP_001461654.1 CDS priC NC_009801.1 525432 525959 R PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' complement(525432..525959) Escherichia coli E24377A 5589648 YP_001461655.1 CDS EcE24377A_0504 NC_009801.1 526029 526406 D identified by match to protein family HMM PF04304; hypothetical protein 526029..526406 Escherichia coli E24377A 5587907 YP_001461656.1 CDS EcE24377A_0505 NC_009801.1 526381 526491 D identified by glimmer; hypothetical protein 526381..526491 Escherichia coli E24377A 5587881 YP_001461657.1 CDS apt NC_009801.1 526559 527110 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 526559..527110 Escherichia coli E24377A 5586321 YP_001461658.1 CDS dnaX NC_009801.1 527239 529170 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 527239..529170 Escherichia coli E24377A 5590530 YP_001461659.1 CDS EcE24377A_0508 NC_009801.1 529199 529576 R identified by glimmer; hypothetical protein complement(529199..529576) Escherichia coli E24377A 5589069 YP_001461660.1 CDS EcE24377A_0509 NC_009801.1 529223 529552 D identified by similarity to GB:AAZ90762.1; match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein 529223..529552 Escherichia coli E24377A 5586516 YP_001461661.1 CDS recR NC_009801.1 529552 530157 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 529552..530157 Escherichia coli E24377A 5588187 YP_001461662.1 CDS htpG NC_009801.1 530267 532141 D molecular chaperone; heat shock protein 90 530267..532141 Escherichia coli E24377A 5586877 YP_001461663.1 CDS adk NC_009801.1 532322 532966 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 532322..532966 Escherichia coli E24377A 5586762 YP_001461664.1 CDS hemH NC_009801.1 533202 534164 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 533202..534164 Escherichia coli E24377A 5586173 YP_001461665.1 CDS aes NC_009801.1 534161 535120 R identified by similarity to SP:P23872; match to protein family HMM PF07859; acetyl esterase complement(534161..535120) Escherichia coli E24377A 5590414 YP_001461666.1 CDS gsk NC_009801.1 535272 536576 D identified by similarity to SP:P0AEW6; match to protein family HMM PF00294; inosine-guanosine kinase 535272..536576 Escherichia coli E24377A 5590882 YP_001461667.1 CDS EcE24377A_0517 NC_009801.1 536709 538385 R YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein complement(536709..538385) Escherichia coli E24377A 5590080 YP_001461668.1 CDS fsr NC_009801.1 538623 539843 R identified by match to protein family HMM PF07690; fosmidomycin resistance protein complement(538623..539843) Escherichia coli E24377A 5587835 YP_001461669.1 CDS ushA NC_009801.1 540061 541713 D catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 540061..541713 Escherichia coli E24377A 5589976 YP_001461670.1 CDS EcE24377A_0520 NC_009801.1 541750 542229 R identified by match to protein family HMM PF04073; match to protein family HMM TIGR00011; hypothetical protein complement(541750..542229) Escherichia coli E24377A 5586983 YP_001461671.1 CDS EcE24377A_0521 NC_009801.1 542433 543227 R identified by match to protein family HMM PF07446; GumN family protein complement(542433..543227) Escherichia coli E24377A 5589609 YP_001461672.1 CDS EcE24377A_0522 NC_009801.1 543311 543706 D identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607; addiction module antidote protein 543311..543706 Escherichia coli E24377A 5586154 YP_001461673.1 CDS copA NC_009801.1 543820 546324 R identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; copper exporting ATPase complement(543820..546324) Escherichia coli E24377A 5590560 YP_001461674.1 CDS glsA1 NC_009801.1 546586 547518 D catalyzes the formation of glutamate from glutamine; glutaminase 546586..547518 Escherichia coli E24377A 5587038 YP_001461675.1 CDS EcE24377A_0525 NC_009801.1 547521 548813 D identified by match to protein family HMM PF00324; match to protein family HMM PF01490; match to protein family HMM PF03845; amino acid permease 547521..548813 Escherichia coli E24377A 5589271 YP_001461676.1 CDS cueR NC_009801.1 548938 549345 D activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 548938..549345 Escherichia coli E24377A 5587899 YP_001461677.1 CDS EcE24377A_0527 NC_009801.1 549346 549804 R identified by match to protein family HMM PF01957; nodulation efficiency family protein complement(549346..549804) Escherichia coli E24377A 5586387 YP_001461678.1 CDS EcE24377A_0528 NC_009801.1 549801 550718 R identified by match to protein family HMM PF01145; hypothetical protein complement(549801..550718) Escherichia coli E24377A 5588911 YP_001461679.1 CDS EcE24377A_0529 NC_009801.1 550864 551541 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 550864..551541 Escherichia coli E24377A 5589651 YP_001461680.1 CDS EcE24377A_0530 NC_009801.1 551528 552307 D identified by match to protein family HMM PF03649; match to protein family HMM TIGR00245; hypothetical protein 551528..552307 Escherichia coli E24377A 5586244 YP_001461681.1 CDS ybbN NC_009801.1 552370 553224 R identified by similarity to SP:P77395; match to protein family HMM PF00085; protein YbbN complement(552370..553224) Escherichia coli E24377A 5587129 YP_001461682.1 CDS EcE24377A_0532 NC_009801.1 553285 554094 R identified by match to protein family HMM PF00106; match to protein family HMM PF08659; short chain dehydrogenase complement(553285..554094) Escherichia coli E24377A 5588268 YP_001461683.1 CDS tesA NC_009801.1 554084 554740 R identified by similarity to SP:P0ADA1; match to protein family HMM PF00657; multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 complement(554084..554740) Escherichia coli E24377A 5587668 YP_001461684.1 CDS EcE24377A_0534 NC_009801.1 554678 555364 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 554678..555364 Escherichia coli E24377A 5589487 YP_001461685.1 CDS EcE24377A_0535 NC_009801.1 555361 557775 D identified by match to protein family HMM PF02687; ABC transporter permease 555361..557775 Escherichia coli E24377A 5588740 YP_001461686.1 CDS EcE24377A_0536 NC_009801.1 558205 562494 D identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; RhsD protein 558205..562494 Escherichia coli E24377A 5588669 YP_001461687.1 CDS EcE24377A_0537 NC_009801.1 562534 562902 D lipoprotein 562534..562902 Escherichia coli E24377A 5589856 YP_001461688.1 CDS EcE24377A_0538 NC_009801.1 562902 563612 D identified by match to protein family HMM PF03527; Rhs domain-containing protein 562902..563612 Escherichia coli E24377A 5589771 YP_001461689.1 CDS selU NC_009801.1 565087 566181 R catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase complement(565087..566181) Escherichia coli E24377A 5588169 YP_001461690.1 CDS EcE24377A_0541 NC_009801.1 566250 567176 R activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS complement(566250..567176) Escherichia coli E24377A 5586407 YP_001461691.1 CDS allA NC_009801.1 567406 567888 D catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 567406..567888 Escherichia coli E24377A 5586554 YP_001461692.1 CDS allR NC_009801.1 567966 568781 D regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 567966..568781 Escherichia coli E24377A 5587443 YP_001461693.1 CDS gcl NC_009801.1 568871 570652 D catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 568871..570652 Escherichia coli E24377A 5586740 YP_001461694.1 CDS hyi NC_009801.1 570665 571441 D identified by match to protein family HMM PF01261; match to protein family HMM TIGR03234; hydroxypyruvate isomerase 570665..571441 Escherichia coli E24377A 5589178 YP_001461695.1 CDS EcE24377A_0546 NC_009801.1 571541 572419 D identified by match to protein family HMM PF03446; match to protein family HMM TIGR01505; 2-hydroxy-3-oxopropionate reductase 571541..572419 Escherichia coli E24377A 5587211 YP_001461696.1 CDS EcE24377A_0547 NC_009801.1 572588 574042 D identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800; allantoin permease 572588..574042 Escherichia coli E24377A 5587684 YP_001461697.1 CDS allB NC_009801.1 574102 575463 D Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 574102..575463 Escherichia coli E24377A 5586304 YP_001461698.1 CDS EcE24377A_0550 NC_009801.1 575520 576821 D identified by match to protein family HMM PF00860; purine permease YbbY 575520..576821 Escherichia coli E24377A 5589898 YP_001461699.1 CDS EcE24377A_0549 NC_009801.1 576482 576574 R identified by glimmer; hypothetical protein complement(576482..576574) Escherichia coli E24377A 5590836 YP_001461700.1 CDS EcE24377A_0551 NC_009801.1 576843 577988 D identified by similarity to SP:P77364; match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase 576843..577988 Escherichia coli E24377A 5589286 YP_001461701.1 CDS EcE24377A_0552 NC_009801.1 578047 578187 D identified by glimmer; hypothetical protein 578047..578187 Escherichia coli E24377A 5586772 YP_001461702.1 CDS EcE24377A_0553 NC_009801.1 578216 579001 R identified by match to protein family HMM PF05899; match to protein family HMM PF07883; match to protein family HMM TIGR03214; hypothetical protein complement(578216..579001) Escherichia coli E24377A 5589533 YP_001461703.1 CDS allC NC_009801.1 579012 580247 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(579012..580247) Escherichia coli E24377A 5588409 YP_001461704.1 CDS allD NC_009801.1 580269 581318 R identified by similarity to SP:P77555; match to protein family HMM PF02615; match to protein family HMM TIGR03175; ureidoglycolate dehydrogenase complement(580269..581318) Escherichia coli E24377A 5588039 YP_001461705.1 CDS EcE24377A_0556 NC_009801.1 581635 583302 D multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 581635..583302 Escherichia coli E24377A 5586054 YP_001461706.1 CDS EcE24377A_0557 NC_009801.1 583312 584571 D identified by match to protein family HMM PF06545; hypothetical protein 583312..584571 Escherichia coli E24377A 5590681 YP_001461707.1 CDS EcE24377A_0558 NC_009801.1 584582 585397 D ylbF; identified by similarity to GB:ABB65130.1; hypothetical protein 584582..585397 Escherichia coli E24377A 5588564 YP_001461708.1 CDS arcC NC_009801.1 585394 586287 D identified by match to protein family HMM PF00696; match to protein family HMM TIGR00746; carbamate kinase 585394..586287 Escherichia coli E24377A 5588659 YP_001461709.1 CDS EcE24377A_0561 NC_009801.1 586324 586431 D identified by glimmer; hypothetical protein 586324..586431 Escherichia coli E24377A 5586456 YP_001461710.1 CDS purK NC_009801.1 586424 587491 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(586424..587491) Escherichia coli E24377A 5588396 YP_001461711.1 CDS purE NC_009801.1 587488 587997 R identified by similarity to SP:P0AG18; match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase catalytic subunit complement(587488..587997) Escherichia coli E24377A 5585948 YP_001461712.1 CDS lpxH NC_009801.1 588115 588837 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(588115..588837) Escherichia coli E24377A 5589752 YP_001461713.1 CDS ppiB NC_009801.1 588840 589334 R identified by similarity to SP:P23869; match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase B complement(588840..589334) Escherichia coli E24377A 5586737 YP_001461714.1 CDS cysS NC_009801.1 589508 590893 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 589508..590893 Escherichia coli E24377A 5586047 YP_001461715.1 CDS EcE24377A_0567 NC_009801.1 590929 591450 R identified by match to protein family HMM PF04307; hypothetical protein complement(590929..591450) Escherichia coli E24377A 5589953 YP_001461716.1 CDS EcE24377A_0569 NC_009801.1 591558 591770 R identified by similarity to SP:P0AAS8; hypothetical protein complement(591558..591770) Escherichia coli E24377A 5590498 YP_001461717.1 CDS folD NC_009801.1 591772 592638 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(591772..592638) Escherichia coli E24377A 5590848 YP_001461718.1 CDS EcE24377A_0571 NC_009801.1 593119 593661 D identified by similarity to SP:P04128; match to protein family HMM PF00419; type-1 fimbrial protein 593119..593661 Escherichia coli E24377A 5588457 YP_001461719.1 CDS EcE24377A_0572 NC_009801.1 593757 593891 D identified by glimmer; hypothetical protein 593757..593891 Escherichia coli E24377A 5588775 YP_001461720.1 CDS fimC NC_009801.1 593881 594573 D identified by match to protein family HMM PF00345; match to protein family HMM PF02753; chaperone protein FimC 593881..594573 Escherichia coli E24377A 5589312 YP_001461721.1 CDS EcE24377A_0575 NC_009801.1 597067 597228 D identified by glimmer; hypothetical protein 597067..597228 Escherichia coli E24377A 5588653 YP_001461722.1 CDS EcE24377A_0576 NC_009801.1 597225 598232 D identified by similarity to GB:AAD17914.1; mannose binding protein FimH 597225..598232 Escherichia coli E24377A 5587202 YP_001461723.1 CDS fimZ NC_009801.1 598761 599393 R activates the production of the major fimbrae protein FimA; transcriptional regulator FimZ complement(598761..599393) Escherichia coli E24377A 5588691 YP_001461724.1 CDS EcE24377A_0579 NC_009801.1 599758 600519 R identified by match to protein family HMM PF00165; AraC family transcriptional regulator complement(599758..600519) Escherichia coli E24377A 5586546 YP_001461725.1 CDS EcE24377A_0580 NC_009801.1 600702 601592 R hypothetical protein complement(600702..601592) Escherichia coli E24377A 5590674 YP_001461726.1 CDS EcE24377A_0581 NC_009801.1 601593 604565 R identified by match to protein family HMM PF00515; match to protein family HMM PF07719; bacteriophage N4 receptor, outer membrane subunit complement(601593..604565) Escherichia coli E24377A 5589025 YP_001461727.1 CDS EcE24377A_0583 NC_009801.1 607057 608193 R identified by match to protein family HMM PF01609; ISEc3, transposase complement(607057..608193) Escherichia coli E24377A 5586798 YP_001461728.1 CDS EcE24377A_0584 NC_009801.1 608297 608608 R identified by glimmer; hypothetical protein complement(608297..608608) Escherichia coli E24377A 5588792 YP_001461729.1 CDS EcE24377A_0585 NC_009801.1 608971 613773 R identified by match to protein family HMM PF05488; match to protein family HMM PF05593; match to protein family HMM TIGR01643; hypothetical protein complement(608971..613773) Escherichia coli E24377A 5589845 YP_001461730.1 CDS EcE24377A_0586 NC_009801.1 613853 614314 R identified by similarity to GB:CAE12649.1; match to protein family HMM PF08786; hypothetical protein complement(613853..614314) Escherichia coli E24377A 5586463 YP_001461731.1 CDS EcE24377A_0587 NC_009801.1 614342 616243 R identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361; ImpA family type VI secretion-associated protein complement(614342..616243) Escherichia coli E24377A 5586910 YP_001461732.1 CDS cusS NC_009801.1 616980 618428 R identified by similarity to SP:P77485; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386; sensor kinase CusS complement(616980..618428) Escherichia coli E24377A 5589793 YP_001461733.1 CDS cusR NC_009801.1 618418 619101 R response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR complement(618418..619101) Escherichia coli E24377A 5587710 YP_001461734.1 CDS cusC NC_009801.1 619258 620640 D with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 619258..620640 Escherichia coli E24377A 5585994 YP_001461735.1 CDS cusF NC_009801.1 620664 620996 D copper-binding protein 620664..620996 Escherichia coli E24377A 5587231 YP_001461736.1 CDS cusB NC_009801.1 621012 622235 D with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 621012..622235 Escherichia coli E24377A 5589561 YP_001461737.1 CDS cusA NC_009801.1 622247 625390 D identified by match to protein family HMM PF00873; match to protein family HMM TIGR00914; cation efflux system protein cusA 622247..625390 Escherichia coli E24377A 5589711 YP_001461738.1 CDS pheP NC_009801.1 625492 626868 D identified by match to protein family HMM PF00324; phenylalanine transporter 625492..626868 Escherichia coli E24377A 5590654 YP_001461739.1 CDS ybdG NC_009801.1 626936 628183 R identified by match to protein family HMM PF00924; small conductance mechanosensitive ion channel (MscS) family protein complement(626936..628183) Escherichia coli E24377A 5587449 YP_001461740.1 CDS nfnB NC_009801.1 628291 628944 R catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase complement(628291..628944) Escherichia coli E24377A 5588626 YP_001461741.1 CDS EcE24377A_0597 NC_009801.1 628992 629084 R identified by glimmer; hypothetical protein complement(628992..629084) Escherichia coli E24377A 5586577 YP_001461742.1 CDS EcE24377A_0598 NC_009801.1 629038 629406 R identified by similarity to GB:BAA35219.1; match to protein family HMM PF04237; hypothetical protein complement(629038..629406) Escherichia coli E24377A 5586825 YP_001461743.1 CDS EcE24377A_0599 NC_009801.1 629471 629719 R identified by match to protein family HMM PF06643; lipoprotein complement(629471..629719) Escherichia coli E24377A 5587827 YP_001461744.1 CDS EcE24377A_0600 NC_009801.1 629785 630903 R ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase complement(629785..630903) Escherichia coli E24377A 5589382 YP_001461745.1 CDS entD NC_009801.1 632133 632762 R identified by similarity to SP:P19925; match to protein family HMM PF01648; phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex complement(632133..632762) Escherichia coli E24377A 5589703 YP_001461746.1 CDS fepA NC_009801.1 632928 635168 R Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA complement(632928..635168) Escherichia coli E24377A 5587372 YP_001461747.1 CDS fes NC_009801.1 635489 636613 D identified by similarity to SP:P13039; match to protein family HMM PF00756; enterobactin/ferric enterobactin esterase 635489..636613 Escherichia coli E24377A 5590648 YP_001461748.1 CDS EcE24377A_0605 NC_009801.1 636616 636834 D identified by match to protein family HMM PF03621; mbtH-like protein 636616..636834 Escherichia coli E24377A 5586323 YP_001461749.1 CDS entF NC_009801.1 636831 640712 D with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 636831..640712 Escherichia coli E24377A 5589658 YP_001461750.1 CDS fepE NC_009801.1 640928 642061 D part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 640928..642061 Escherichia coli E24377A 5586632 YP_001461751.1 CDS fepC NC_009801.1 642058 642873 R with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein complement(642058..642873) Escherichia coli E24377A 5587697 YP_001461752.1 CDS fepG NC_009801.1 642870 643862 R with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease complement(642870..643862) Escherichia coli E24377A 5585928 YP_001461753.1 CDS fepD NC_009801.1 643859 644863 R with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein complement(643859..644863) Escherichia coli E24377A 5587284 YP_001461754.1 CDS EcE24377A_0611 NC_009801.1 644974 646224 D protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 644974..646224 Escherichia coli E24377A 5585992 YP_001461755.1 CDS fepB NC_009801.1 646228 647184 R with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein complement(646228..647184) Escherichia coli E24377A 5590746 YP_001461756.1 CDS entC NC_009801.1 647559 648734 D identified by similarity to SP:P0AEJ2; match to protein family HMM PF00425; match to protein family HMM TIGR00543; isochorismate synthase 647559..648734 Escherichia coli E24377A 5588176 YP_001461757.1 CDS entE NC_009801.1 648744 650354 D bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 648744..650354 Escherichia coli E24377A 5586822 YP_001461758.1 CDS entB NC_009801.1 650368 651225 D identified by similarity to SP:P0ADI4; match to protein family HMM PF00550; match to protein family HMM PF00857; isochorismatase 650368..651225 Escherichia coli E24377A 5588941 YP_001461759.1 CDS entA NC_009801.1 651225 651971 D catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 651225..651971 Escherichia coli E24377A 5588316 YP_001461760.1 CDS EcE24377A_0617 NC_009801.1 651974 652387 D identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 651974..652387 Escherichia coli E24377A 5588952 YP_001461761.1 CDS cstA NC_009801.1 652568 654673 D identified by similarity to SP:P15078; match to protein family HMM PF02554; carbon starvation protein A 652568..654673 Escherichia coli E24377A 5589484 YP_001461762.1 CDS EcE24377A_0619 NC_009801.1 654855 655052 D identified by similarity to SP:P0AAT1; match to protein family HMM PF04328; hypothetical protein 654855..655052 Escherichia coli E24377A 5586589 YP_001461763.1 CDS EcE24377A_0620 NC_009801.1 655062 656150 R member of the iron-containing alcohol dehydrogenase; unknown function; hypothetical protein complement(655062..656150) Escherichia coli E24377A 5590508 YP_001461764.1 CDS EcE24377A_0621 NC_009801.1 656259 657419 D catalyzes the transfer of an amino moiety; aminotransferase 656259..657419 Escherichia coli E24377A 5590439 YP_001461765.1 CDS EcE24377A_0622 NC_009801.1 657420 658037 R identified by match to protein family HMM PF02195; IbrB protein complement(657420..658037) Escherichia coli E24377A 5589247 YP_001461766.1 CDS EcE24377A_0623 NC_009801.1 658022 659242 R identified by match to protein family HMM PF01507; IbrA protein complement(658022..659242) Escherichia coli E24377A 5586050 YP_001461767.1 CDS EcE24377A_0624 NC_009801.1 659389 660291 R identified by match to protein family HMM PF00126; LysR family transcriptional regulator complement(659389..660291) Escherichia coli E24377A 5589398 YP_001461768.1 CDS dsbG NC_009801.1 660500 661246 R Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase complement(660500..661246) Escherichia coli E24377A 5586095 YP_001461769.1 CDS ahpC NC_009801.1 661618 662181 D with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase 661618..662181 Escherichia coli E24377A 5587391 YP_001461770.1 CDS ahpF NC_009801.1 662396 663991 D identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR03140; alkyl hydroperoxide reductase 662396..663991 Escherichia coli E24377A 5588604 YP_001461771.1 CDS uspG NC_009801.1 664112 664540 R identified by similarity to SP:P39177; match to protein family HMM PF00582; universal stress protein G complement(664112..664540) Escherichia coli E24377A 5587852 YP_001461772.1 CDS EcE24377A_0629 NC_009801.1 664472 664642 D identified by glimmer; hypothetical protein 664472..664642 Escherichia coli E24377A 5589479 YP_001461773.1 CDS EcE24377A_0630 NC_009801.1 664761 665999 D identified by match to protein family HMM PF00107; match to protein family HMM PF08240; zinc-binding dehydrogenase oxidoreductase 664761..665999 Escherichia coli E24377A 5588012 YP_001461774.1 CDS EcE24377A_0631 NC_009801.1 666003 666131 R identified by glimmer; hypothetical protein complement(666003..666131) Escherichia coli E24377A 5588516 YP_001461775.1 CDS rnk NC_009801.1 666230 666640 R Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator complement(666230..666640) Escherichia coli E24377A 5587908 YP_001461776.1 CDS rna NC_009801.1 666870 667676 R identified by similarity to SP:P21338; match to protein family HMM PF00445; ribonuclease I complement(666870..667676) Escherichia coli E24377A 5586275 YP_001461777.1 CDS citT NC_009801.1 667790 669253 R identified by similarity to SP:P0AE74; match to protein family HMM PF00939; match to protein family HMM TIGR00785; citrate transporter complement(667790..669253) Escherichia coli E24377A 5589151 YP_001461778.1 CDS citG NC_009801.1 669304 670182 R catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase complement(669304..670182) Escherichia coli E24377A 5588447 YP_001461779.1 CDS citX NC_009801.1 670157 670708 R 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase complement(670157..670708) Escherichia coli E24377A 5586612 YP_001461780.1 CDS citF NC_009801.1 670712 672244 R identified by match to protein family HMM PF04223; match to protein family HMM TIGR01584; citrate lyase subunit alpha complement(670712..672244) Escherichia coli E24377A 5587439 YP_001461781.1 CDS citE NC_009801.1 672255 673163 R identified by match to protein family HMM PF03328; match to protein family HMM TIGR01588; citrate (pro-3S)-lyase subunit beta complement(672255..673163) Escherichia coli E24377A 5586807 YP_001461782.1 CDS citD NC_009801.1 673160 673456 R acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma complement(673160..673456) Escherichia coli E24377A 5589129 YP_001461783.1 CDS EcE24377A_0641 NC_009801.1 674452 674598 D identified by glimmer; hypothetical protein 674452..674598 Escherichia coli E24377A 5588387 YP_001461784.1 CDS dpiB NC_009801.1 674908 676566 D identified by similarity to SP:P77510; match to protein family HMM PF02518; sensor histidine kinase DpiB 674908..676566 Escherichia coli E24377A 5589331 YP_001461785.1 CDS dpiA NC_009801.1 676535 677215 D regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 676535..677215 Escherichia coli E24377A 5588711 YP_001461786.1 CDS dcuC NC_009801.1 677256 678641 R responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC complement(677256..678641) Escherichia coli E24377A 5586869 YP_001461787.1 CDS EcE24377A_0645 NC_009801.1 678686 678796 R identified by glimmer; hypothetical protein complement(678686..678796) Escherichia coli E24377A 5588491 YP_001461788.1 CDS EcE24377A_0646 NC_009801.1 679000 679107 D identified by glimmer; hypothetical protein 679000..679107 Escherichia coli E24377A 5586617 YP_001461789.1 CDS pagP NC_009801.1 679230 679790 D catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 679230..679790 Escherichia coli E24377A 5586288 YP_001461790.1 CDS cspE NC_009801.1 679965 680174 D member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 679965..680174 Escherichia coli E24377A 5587980 YP_001461791.1 CDS crcB NC_009801.1 680228 680611 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(680228..680611) Escherichia coli E24377A 5590216 YP_001461792.1 CDS EcE24377A_0650 NC_009801.1 680704 681492 D identified by match to protein family HMM PF00795; carbon-nitrogen family hydrolase 680704..681492 Escherichia coli E24377A 5586278 YP_001461793.1 CDS tatE NC_009801.1 681621 681824 D TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase E 681621..681824 Escherichia coli E24377A 5590662 YP_001461794.1 CDS lipA NC_009801.1 681925 682890 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(681925..682890) Escherichia coli E24377A 5587793 YP_001461795.1 CDS EcE24377A_0653 NC_009801.1 682989 683102 R identified by glimmer; hypothetical protein complement(682989..683102) Escherichia coli E24377A 5586805 YP_001461796.1 CDS EcE24377A_0654 NC_009801.1 683099 684052 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator complement(683099..684052) Escherichia coli E24377A 5590543 YP_001461797.1 CDS lipB NC_009801.1 684312 684953 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(684312..684953) Escherichia coli E24377A 5588748 YP_001461798.1 CDS EcE24377A_0656 NC_009801.1 685054 685317 R identified by similarity to SP:P0A8J4; match to protein family HMM PF04359; hypothetical protein complement(685054..685317) Escherichia coli E24377A 5586109 YP_001461799.1 CDS dacA NC_009801.1 685427 686638 R penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase complement(685427..686638) Escherichia coli E24377A 5586365 YP_001461800.1 CDS EcE24377A_0659 NC_009801.1 686661 686801 D hypothetical protein 686661..686801 Escherichia coli E24377A 5587045 YP_001461801.1 CDS rlpA NC_009801.1 686778 687866 R identified by similarity to SP:P10100; match to protein family HMM PF03330; match to protein family HMM PF05036; match to protein family HMM TIGR00413; rare lipoprotein A complement(686778..687866) Escherichia coli E24377A 5586476 YP_001461802.1 CDS mrdB NC_009801.1 687877 688989 R identified by similarity to SP:P0ABG7; match to protein family HMM PF01098; match to protein family HMM TIGR02210; cell wall shape-determining protein complement(687877..688989) Escherichia coli E24377A 5590846 YP_001461803.1 CDS mrdA NC_009801.1 688992 690893 R identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM TIGR03423; penicillin-binding protein 2 complement(688992..690893) Escherichia coli E24377A 5587497 YP_001461804.1 CDS EcE24377A_0662 NC_009801.1 690924 691391 R SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(690924..691391) Escherichia coli E24377A 5589329 YP_001461805.1 CDS EcE24377A_0663 NC_009801.1 691395 691712 R identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090; hypothetical protein complement(691395..691712) Escherichia coli E24377A 5587998 YP_001461806.1 CDS cobC NC_009801.1 691972 692583 R identified by similarity to SP:P52086; match to protein family HMM PF00300; match to protein family HMM TIGR03162; alpha-ribazole-5'-phosphate phosphatase complement(691972..692583) Escherichia coli E24377A 5586346 YP_001461807.1 CDS nadD NC_009801.1 692607 693248 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(692607..693248) Escherichia coli E24377A 5588028 YP_001461808.1 CDS holA NC_009801.1 693250 694281 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(693250..694281) Escherichia coli E24377A 5586759 YP_001461809.1 CDS EcE24377A_0667 NC_009801.1 694281 694862 R rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB complement(694281..694862) Escherichia coli E24377A 5589319 YP_001461810.1 CDS leuS NC_009801.1 694877 697459 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(694877..697459) Escherichia coli E24377A 5586204 YP_001461811.1 CDS EcE24377A_0669 NC_009801.1 697694 698176 D identified by similarity to SP:P0AAT9; match to protein family HMM PF07295; hypothetical protein 697694..698176 Escherichia coli E24377A 5589276 YP_001461812.1 CDS EcE24377A_0670 NC_009801.1 698246 699103 R identified by similarity to GB:AAV88692.1; match to protein family HMM PF08238; hypothetical protein complement(698246..699103) Escherichia coli E24377A 5587105 YP_001461813.1 CDS EcE24377A_0671 NC_009801.1 699051 699224 R identified by glimmer; hypothetical protein complement(699051..699224) Escherichia coli E24377A 5590542 YP_001461814.1 CDS EcE24377A_0672 NC_009801.1 699214 699354 D identified by glimmer; hypothetical protein 699214..699354 Escherichia coli E24377A 5586482 YP_001461815.1 CDS EcE24377A_0673 NC_009801.1 699388 700095 D identified by similarity to SP:P77627; match to protein family HMM PF06889; hypothetical protein 699388..700095 Escherichia coli E24377A 5589710 YP_001461816.1 CDS EcE24377A_0674 NC_009801.1 700092 701519 D identified by match to protein family HMM PF00226; DnaJ domain-containing protein 700092..701519 Escherichia coli E24377A 5588449 YP_001461817.1 CDS EcE24377A_0675 NC_009801.1 701529 702083 R identified by similarity to GB:BAB34108.1; match to protein family HMM PF08238; hypothetical protein complement(701529..702083) Escherichia coli E24377A 5587478 YP_001461818.1 CDS EcE24377A_0676 NC_009801.1 702185 702892 D identified by similarity to SP:P77427; match to protein family HMM PF06889; hypothetical protein 702185..702892 Escherichia coli E24377A 5590161 YP_001461819.1 CDS EcE24377A_0677 NC_009801.1 702889 704340 D identified by match to protein family HMM PF00226; DnaJ domain-containing protein 702889..704340 Escherichia coli E24377A 5587653 YP_001461820.1 CDS hscC NC_009801.1 704400 706070 R identified by match to protein family HMM PF00012; molecular chaperone DnaK complement(704400..706070) Escherichia coli E24377A 5586020 YP_001461821.1 CDS rihA NC_009801.1 706154 707089 R Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 complement(706154..707089) Escherichia coli E24377A 5589986 YP_001461822.1 CDS gltL NC_009801.1 707207 707932 R identified by match to protein family HMM PF00005; glutamate/aspartate ABC transporter ATP-binding protein complement(707207..707932) Escherichia coli E24377A 5588295 YP_001461823.1 CDS gltK NC_009801.1 707932 708606 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamate/aspartate ABC transporter permease GltK complement(707932..708606) Escherichia coli E24377A 5588342 YP_001461824.1 CDS gltJ NC_009801.1 708606 709346 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamate/aspartate ABC transporter permease GltJ complement(708606..709346) Escherichia coli E24377A 5587029 YP_001461825.1 CDS gltI NC_009801.1 709516 710424 R identified by match to protein family HMM PF00497; glutamate and aspartate transporter subunit complement(709516..710424) Escherichia coli E24377A 5589148 YP_001461826.1 CDS EcE24377A_0684 NC_009801.1 710559 710681 D identified by glimmer; hypothetical protein 710559..710681 Escherichia coli E24377A 5588834 YP_001461827.1 CDS EcE24377A_0685 NC_009801.1 710879 712756 D identified by match to protein family HMM PF01694; match to protein family HMM TIGR02276; S54 family peptidase 710879..712756 Escherichia coli E24377A 5589471 YP_001461828.1 CDS lnt NC_009801.1 712834 714372 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(712834..714372) Escherichia coli E24377A 5587043 YP_001461829.1 CDS corC NC_009801.1 714397 715275 R identified by match to protein family HMM PF00571; match to protein family HMM PF03471; magnesium and cobalt efflux protein CorC complement(714397..715275) Escherichia coli E24377A 5590390 YP_001461830.1 CDS EcE24377A_0688 NC_009801.1 715365 715832 R identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043; metalloprotease complement(715365..715832) Escherichia coli E24377A 5588216 YP_001461831.1 CDS EcE24377A_0689 NC_009801.1 715829 716869 R identified by match to protein family HMM PF02562; PhoH family protein complement(715829..716869) Escherichia coli E24377A 5588640 YP_001461832.1 CDS EcE24377A_0691 NC_009801.1 716888 717031 D identified by glimmer; hypothetical protein 716888..717031 Escherichia coli E24377A 5590736 YP_001461833.1 CDS miaB NC_009801.1 717022 718446 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(717022..718446) Escherichia coli E24377A 5586142 YP_001461834.1 CDS ubiF NC_009801.1 718592 719767 D catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 718592..719767 Escherichia coli E24377A 5588753 YP_001461835.1 CDS asnB NC_009801.1 720893 722557 R functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B complement(720893..722557) Escherichia coli E24377A 5587367 YP_001461836.1 CDS nagD NC_009801.1 722814 723566 R identified by match to protein family HMM PF00702; match to protein family HMM TIGR01460; UMP phosphatase complement(722814..723566) Escherichia coli E24377A 5587832 YP_001461837.1 CDS nagC NC_009801.1 723614 724834 R identified by match to protein family HMM PF00480; N-acetylglucosamine repressor complement(723614..724834) Escherichia coli E24377A 5589955 YP_001461838.1 CDS nagA NC_009801.1 724843 725991 R catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase complement(724843..725991) Escherichia coli E24377A 5586629 YP_001461839.1 CDS nagB NC_009801.1 726051 726851 R catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase complement(726051..726851) Escherichia coli E24377A 5586783 YP_001461840.1 CDS nagE NC_009801.1 727184 729130 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunit IIABC 727184..729130 Escherichia coli E24377A 5587295 YP_001461841.1 CDS EcE24377A_0704 NC_009801.1 729100 729222 R identified by glimmer; hypothetical protein complement(729100..729222) Escherichia coli E24377A 5587978 YP_001461842.1 CDS glnS NC_009801.1 729333 730997 D catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 729333..730997 Escherichia coli E24377A 5586917 YP_001461843.1 CDS EcE24377A_0707 NC_009801.1 731000 731185 R identified by glimmer; hypothetical protein complement(731000..731185) Escherichia coli E24377A 5590160 YP_001461844.1 CDS EcE24377A_0708 NC_009801.1 731148 731252 R identified by glimmer; hypothetical protein complement(731148..731252) Escherichia coli E24377A 5589659 YP_001461845.1 CDS oprD NC_009801.1 731443 732849 D identified by match to protein family HMM PF03573; porin 731443..732849 Escherichia coli E24377A 5586646 YP_001461846.1 CDS EcE24377A_0710 NC_009801.1 732899 733225 D lipoprotein 732899..733225 Escherichia coli E24377A 5586254 YP_001461847.1 CDS fur NC_009801.1 733310 733756 R negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator complement(733310..733756) Escherichia coli E24377A 5586769 YP_001461848.1 CDS fldA NC_009801.1 734045 734692 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(734045..734692) Escherichia coli E24377A 5586978 YP_001461849.1 CDS EcE24377A_0713 NC_009801.1 734715 735008 R identified by match to protein family HMM PF01402; LexA regulated protein complement(734715..735008) Escherichia coli E24377A 5590676 YP_001461850.1 CDS EcE24377A_0714 NC_009801.1 735148 735912 R identified by match to protein family HMM PF00561; match to protein family HMM PF07819; hypothetical protein complement(735148..735912) Escherichia coli E24377A 5589739 YP_001461851.1 CDS seqA NC_009801.1 736097 736642 D negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 736097..736642 Escherichia coli E24377A 5588076 YP_001461852.1 CDS pgm NC_009801.1 736668 738308 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 736668..738308 Escherichia coli E24377A 5587018 YP_001461853.1 CDS potE NC_009801.1 738364 739683 R catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter complement(738364..739683) Escherichia coli E24377A 5587738 YP_001461854.1 CDS speF NC_009801.1 739680 741887 R identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; ornithine decarboxylase complement(739680..741887) Escherichia coli E24377A 5590857 YP_001461855.1 CDS EcE24377A_0719 NC_009801.1 742412 742546 D identified by similarity to GB:AAN42241.1; hypothetical protein 742412..742546 Escherichia coli E24377A 5590401 YP_001461856.1 CDS kdpE NC_009801.1 742568 743245 R response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE complement(742568..743245) Escherichia coli E24377A 5587709 YP_001461857.1 CDS kdpD NC_009801.1 743242 745926 R sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD complement(743242..745926) Escherichia coli E24377A 5585937 YP_001461858.1 CDS kdpC NC_009801.1 745919 746491 R One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C complement(745919..746491) Escherichia coli E24377A 5587111 YP_001461859.1 CDS kdpB NC_009801.1 746500 748548 R One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B complement(746500..748548) Escherichia coli E24377A 5589994 YP_001461860.1 CDS kdpA NC_009801.1 748571 750244 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(748571..750244) Escherichia coli E24377A 5587423 YP_001461861.1 CDS kdpF NC_009801.1 750244 750447 R identified by match to protein family HMM TIGR02115; K+-transporting ATPase subunit F complement(750244..750447) Escherichia coli E24377A 5587180 YP_001461862.1 CDS EcE24377A_0726 NC_009801.1 750645 750851 D identified by similarity to GB:AAN79258.1; hypothetical protein 750645..750851 Escherichia coli E24377A 5587162 YP_001461863.1 CDS EcE24377A_0727 NC_009801.1 751094 755287 D identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; protein rhsA 751094..755287 Escherichia coli E24377A 5586199 YP_001461864.1 CDS EcE24377A_0728 NC_009801.1 755731 757164 D identified by match to protein family HMM PF03527; RHS domain-containing protein 755731..757164 Escherichia coli E24377A 5589111 YP_001461865.1 CDS EcE24377A_0729 NC_009801.1 757161 757730 D identified by glimmer; hypothetical protein 757161..757730 Escherichia coli E24377A 5590755 YP_001461866.1 CDS EcE24377A_0730 NC_009801.1 757956 758210 D identified by similarity to GB:BAA35363.1; ISEc2, transposase 757956..758210 Escherichia coli E24377A 5590833 YP_001461867.1 CDS EcE24377A_0732 NC_009801.1 759245 759754 D identified by similarity to GB:AAN79259.1; match to protein family HMM PF08349; hypothetical protein 759245..759754 Escherichia coli E24377A 5588227 YP_001461868.1 CDS phrB NC_009801.1 759751 761169 D UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 759751..761169 Escherichia coli E24377A 5586035 YP_001461869.1 CDS EcE24377A_0734 NC_009801.1 761211 762692 R identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; amino acid/peptide transporter complement(761211..762692) Escherichia coli E24377A 5589934 YP_001461870.1 CDS EcE24377A_0735 NC_009801.1 762963 763706 D identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486; hydrolase-oxidase 762963..763706 Escherichia coli E24377A 5589598 YP_001461871.1 CDS EcE24377A_0736 NC_009801.1 763729 764385 D identified by match to protein family HMM PF02682; match to protein family HMM TIGR00370; allophanate hydrolase, subunit 1 763729..764385 Escherichia coli E24377A 5587117 YP_001461872.1 CDS EcE24377A_0737 NC_009801.1 764379 765311 D identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724; allophanate hydrolase subunit 2 764379..765311 Escherichia coli E24377A 5589396 YP_001461873.1 CDS EcE24377A_0738 NC_009801.1 765301 766035 D identified by match to protein family HMM PF03746; LamB/YcsF family protein 765301..766035 Escherichia coli E24377A 5587982 YP_001461874.1 CDS nei NC_009801.1 766071 766862 D 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 766071..766862 Escherichia coli E24377A 5589167 YP_001461875.1 CDS EcE24377A_0742 NC_009801.1 768056 769117 R identified by similarity to GB:AAZ87425.1; hypothetical protein complement(768056..769117) Escherichia coli E24377A 5587356 YP_001461876.1 CDS EcE24377A_0743 NC_009801.1 769114 769845 R identified by match to protein family HMM PF00345; match to protein family HMM PF02753; periplasmic pilus chaperone family protein complement(769114..769845) Escherichia coli E24377A 5589300 YP_001461877.1 CDS EcE24377A_0744 NC_009801.1 769860 772361 R identified by match to protein family HMM PF00577; fimbrial usher family protein complement(769860..772361) Escherichia coli E24377A 5588548 YP_001461878.1 CDS EcE24377A_0745 NC_009801.1 772370 772936 R identified by similarity to SP:P04128; match to protein family HMM PF00419; type 1 fimbrial protein complement(772370..772936) Escherichia coli E24377A 5586553 YP_001461879.1 CDS EcE24377A_0746 NC_009801.1 773008 773136 R identified by glimmer; hypothetical protein complement(773008..773136) Escherichia coli E24377A 5587665 YP_001461880.1 CDS gltA NC_009801.1 773327 774610 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(773327..774610) Escherichia coli E24377A 5588872 YP_001461881.1 CDS sdhC NC_009801.1 775304 775708 D identified by match to protein family HMM PF01127; match to protein family HMM TIGR02970; succinate dehydrogenase cytochrome b556 large membrane subunit 775304..775708 Escherichia coli E24377A 5590581 YP_001461882.1 CDS sdhD NC_009801.1 775702 776049 D identified by match to protein family HMM TIGR02968; succinate dehydrogenase cytochrome b556 small membrane subunit 775702..776049 Escherichia coli E24377A 5590116 YP_001461883.1 CDS sdhA NC_009801.1 776049 777815 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 776049..777815 Escherichia coli E24377A 5587072 YP_001461884.1 CDS sdhB NC_009801.1 777831 778547 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 777831..778547 Escherichia coli E24377A 5590181 YP_001461885.1 CDS sucA NC_009801.1 778748 781549 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 778748..781549 Escherichia coli E24377A 5587339 YP_001461886.1 CDS sucB NC_009801.1 781564 782781 D component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 781564..782781 Escherichia coli E24377A 5589616 YP_001461887.1 CDS sucC NC_009801.1 782875 784041 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 782875..784041 Escherichia coli E24377A 5585909 YP_001461888.1 CDS sucD NC_009801.1 784041 784910 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 784041..784910 Escherichia coli E24377A 5587454 YP_001461889.1 CDS farR NC_009801.1 785014 785736 R regulates the succiny-lCoA synthetase operon; DNA-binding transcriptional repressor MngR complement(785014..785736) Escherichia coli E24377A 5587788 YP_001461890.1 CDS EcE24377A_0757 NC_009801.1 785905 787821 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC 785905..787821 Escherichia coli E24377A 5588842 YP_001461891.1 CDS EcE24377A_0758 NC_009801.1 787839 790472 D identified by match to protein family HMM PF01074; match to protein family HMM PF07748; alpha-mannosidase 787839..790472 Escherichia coli E24377A 5588477 YP_001461892.1 CDS EcE24377A_0760 NC_009801.1 790801 790905 R identified by glimmer; hypothetical protein complement(790801..790905) Escherichia coli E24377A 5586785 YP_001461893.1 CDS cydA NC_009801.1 791319 792887 D identified by match to protein family HMM PF01654; cytochrome d ubiquinol oxidase, subunit I 791319..792887 Escherichia coli E24377A 5590437 YP_001461894.1 CDS cydB NC_009801.1 792903 794042 D identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203; cytochrome d ubiquinol oxidase, subunit II 792903..794042 Escherichia coli E24377A 5589992 YP_001461895.1 CDS EcE24377A_0763 NC_009801.1 794057 794170 D identified by match to protein family HMM PF08173; match to protein family HMM TIGR02106; cyd operon protein YbgT 794057..794170 Escherichia coli E24377A 5586034 YP_001461896.1 CDS EcE24377A_0764 NC_009801.1 794170 794463 D identified by match to protein family HMM TIGR02112; hypothetical protein 794170..794463 Escherichia coli E24377A 5590715 YP_001461897.1 CDS ybgC NC_009801.1 794613 795017 D catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase 794613..795017 Escherichia coli E24377A 5587219 YP_001461898.1 CDS tolQ NC_009801.1 795014 795706 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 795014..795706 Escherichia coli E24377A 5589232 YP_001461899.1 CDS tolR NC_009801.1 795710 796138 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 795710..796138 Escherichia coli E24377A 5587282 YP_001461900.1 CDS tolA NC_009801.1 796203 797501 D inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 796203..797501 Escherichia coli E24377A 5587336 YP_001461901.1 CDS tolB NC_009801.1 797634 798926 D forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 797634..798926 Escherichia coli E24377A 5589305 YP_001461902.1 CDS pal NC_009801.1 798961 799482 D identified by match to protein family HMM PF00691; match to protein family HMM TIGR02802; peptidoglycan-associated outer membrane lipoprotein 798961..799482 Escherichia coli E24377A 5590091 YP_001461903.1 CDS ygbF NC_009801.1 799492 800283 D periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 799492..800283 Escherichia coli E24377A 5590492 YP_001461904.1 CDS nadA NC_009801.1 801549 802592 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 801549..802592 Escherichia coli E24377A 5587082 YP_001461905.1 CDS pnuC NC_009801.1 802645 803349 D identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528; nicotinamide mononucleotide transporter PnuC 802645..803349 Escherichia coli E24377A 5587151 YP_001461906.1 CDS zitB NC_009801.1 803346 804287 R involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB complement(803346..804287) Escherichia coli E24377A 5589948 YP_001461907.1 CDS EcE24377A_0780 NC_009801.1 804401 804781 R hypothetical protein complement(804401..804781) Escherichia coli E24377A 5586918 YP_001461908.1 CDS aroG NC_009801.1 805097 806149 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 805097..806149 Escherichia coli E24377A 5586458 YP_001461909.1 CDS gpmA NC_009801.1 806308 807060 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(806308..807060) Escherichia coli E24377A 5587326 YP_001461910.1 CDS galM NC_009801.1 807262 808302 R catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase complement(807262..808302) Escherichia coli E24377A 5586111 YP_001461911.1 CDS galK NC_009801.1 808296 809444 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(808296..809444) Escherichia coli E24377A 5586335 YP_001461912.1 CDS galT NC_009801.1 809448 810494 R catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(809448..810494) Escherichia coli E24377A 5588025 YP_001461913.1 CDS galE NC_009801.1 810504 811520 R identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF05368; match to protein family HMM PF07993; match to protein family HMM TIGR01179; UDP-galactose-4-epimerase complement(810504..811520) Escherichia coli E24377A 5590101 YP_001461914.1 CDS modF NC_009801.1 811781 813253 R contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF complement(811781..813253) Escherichia coli E24377A 5586971 YP_001461915.1 CDS modE NC_009801.1 813321 814109 R represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE complement(813321..814109) Escherichia coli E24377A 5587957 YP_001461916.1 CDS EcE24377A_0789 NC_009801.1 814238 814387 D hypothetical protein 814238..814387 Escherichia coli E24377A 5590684 YP_001461917.1 CDS modA NC_009801.1 814553 815326 D with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 814553..815326 Escherichia coli E24377A 5587973 YP_001461918.1 CDS modB NC_009801.1 815326 816015 D part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 815326..816015 Escherichia coli E24377A 5588736 YP_001461919.1 CDS modC NC_009801.1 816018 817076 D Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 816018..817076 Escherichia coli E24377A 5587838 YP_001461920.1 CDS ybhA NC_009801.1 817077 817895 R YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase complement(817077..817895) Escherichia coli E24377A 5587975 YP_001461921.1 CDS pgl NC_009801.1 818050 819045 D catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 818050..819045 Escherichia coli E24377A 5590523 YP_001461922.1 CDS EcE24377A_0795 NC_009801.1 819086 820039 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(819086..820039) Escherichia coli E24377A 5586348 YP_001461923.1 CDS EcE24377A_0796 NC_009801.1 820223 821275 D identified by similarity to SP:P0AAV8; match to protein family HMM PF04303; hypothetical protein 820223..821275 Escherichia coli E24377A 5586564 YP_001461924.1 CDS EcE24377A_0797 NC_009801.1 821351 822784 D identified by match to protein family HMM PF00939; match to protein family HMM PF03600; match to protein family HMM TIGR00785; anion transporter 821351..822784 Escherichia coli E24377A 5588915 YP_001461925.1 CDS EcE24377A_0798 NC_009801.1 822943 825228 D identified by match to protein family HMM PF00330; match to protein family HMM PF00694; hypothetical protein 822943..825228 Escherichia coli E24377A 5587820 YP_001461926.1 CDS EcE24377A_0799 NC_009801.1 825462 826745 R outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase; pectinesterase complement(825462..826745) Escherichia coli E24377A 5585974 YP_001461927.1 CDS EcE24377A_0800 NC_009801.1 826880 827950 R identified by match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM PF09003; phage integrase complement(826880..827950) Escherichia coli E24377A 5587327 YP_001461928.1 CDS EcE24377A_0801 NC_009801.1 829409 829630 R identified by match to protein family HMM PF01258; match to protein family HMM TIGR02419; phage/conjugal plasmid C-4 type zinc finger protein complement(829409..829630) Escherichia coli E24377A 5588816 YP_001461929.1 CDS EcE24377A_0802 NC_009801.1 829637 829726 R identified by glimmer; hypothetical protein complement(829637..829726) Escherichia coli E24377A 5590682 YP_001461930.1 CDS EcE24377A_0803 NC_009801.1 829729 830010 R identified by similarity to GB:BAB34229.1; hypothetical protein complement(829729..830010) Escherichia coli E24377A 5589827 YP_001461931.1 CDS exo NC_009801.1 830364 831044 R identified by similarity to SP:P03697; exonuclease complement(830364..831044) Escherichia coli E24377A 5586462 YP_001461932.1 CDS bet NC_009801.1 831041 831826 R identified by similarity to SP:P03698; match to protein family HMM PF03837; match to protein family HMM TIGR01913; phage recombination protein Bet complement(831041..831826) Escherichia coli E24377A 5590206 YP_001461933.1 CDS gam NC_009801.1 831832 832128 R identified by similarity to SP:P03702; match to protein family HMM PF06064; host-nuclease inhibitor protein Gam complement(831832..832128) Escherichia coli E24377A 5587901 YP_001461934.1 CDS kiL NC_009801.1 832204 832410 R identified by similarity to SP:P38393; protein KiL complement(832204..832410) Escherichia coli E24377A 5588162 YP_001461935.1 CDS EcE24377A_0808 NC_009801.1 833008 833763 R identified by match to protein family HMM PF00717; match to protein family HMM PF01381; repressor protein complement(833008..833763) Escherichia coli E24377A 5590038 YP_001461936.1 CDS EcE24377A_0809 NC_009801.1 834102 834641 D identified by match to protein family HMM PF06254; hypothetical protein 834102..834641 Escherichia coli E24377A 5588462 YP_001461937.1 CDS EcE24377A_0811 NC_009801.1 835654 836355 D identified by match to protein family HMM PF06992; replication protein P 835654..836355 Escherichia coli E24377A 5590281 YP_001461938.1 CDS EcE24377A_0812 NC_009801.1 836352 836654 D hypothetical protein 836352..836654 Escherichia coli E24377A 5590725 YP_001461939.1 CDS emrE NC_009801.1 836722 837054 D member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 836722..837054 Escherichia coli E24377A 5586437 YP_001461940.1 CDS EcE24377A_0815 NC_009801.1 839146 840684 R identified by match to protein family HMM PF03050; IS66 family transposase complement(839146..840684) Escherichia coli E24377A 5586778 YP_001461941.1 CDS EcE24377A_0816 NC_009801.1 840734 841081 R identified by match to protein family HMM PF05717; IS66 family orf2 complement(840734..841081) Escherichia coli E24377A 5589667 YP_001461942.1 CDS EcE24377A_0817 NC_009801.1 841078 841467 R identified by match to protein family HMM PF01527; IS66 family orf1 complement(841078..841467) Escherichia coli E24377A 5590204 YP_001461943.1 CDS EcE24377A_0818 NC_009801.1 841896 842678 D identified by glimmer; hypothetical protein 841896..842678 Escherichia coli E24377A 5589203 YP_001461944.1 CDS EcE24377A_0819 NC_009801.1 842871 843326 D DLP12 prophage; hypothetical protein 842871..843326 Escherichia coli E24377A 5588429 YP_001461945.1 CDS EcE24377A_0820 NC_009801.1 843489 843779 D identified by match to protein family HMM PF07102; hypothetical protein 843489..843779 Escherichia coli E24377A 5587192 YP_001461946.1 CDS rusA NC_009801.1 843776 844138 D DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 843776..844138 Escherichia coli E24377A 5588919 YP_001461947.1 CDS EcE24377A_0822 NC_009801.1 844138 844275 D identified by similarity to SP:Q47272; hypothetical protein 844138..844275 Escherichia coli E24377A 5588934 YP_001461948.1 CDS EcE24377A_0823 NC_009801.1 844361 844744 D identified by similarity to SP:Q47274; match to protein family HMM PF06530; phage antitermination Q 844361..844744 Escherichia coli E24377A 5590567 YP_001461949.1 CDS EcE24377A_0824 NC_009801.1 844933 846015 R identified by similarity to SP:P07238; match to protein family HMM PF00267; outer membrane porin protein LC complement(844933..846015) Escherichia coli E24377A 5588743 YP_001461950.1 CDS EcE24377A_0825 NC_009801.1 845942 846076 R identified by glimmer; hypothetical protein complement(845942..846076) Escherichia coli E24377A 5587528 YP_001461951.1 CDS EcE24377A_0826 NC_009801.1 846604 846819 D identified by match to protein family HMM PF04971; lysis protein S 846604..846819 Escherichia coli E24377A 5590489 YP_001461952.1 CDS EcE24377A_0827 NC_009801.1 846819 847316 D identified by match to protein family HMM PF00959; phage lysozyme 846819..847316 Escherichia coli E24377A 5586299 YP_001461953.1 CDS EcE24377A_0828 NC_009801.1 847313 847750 D identified by match to protein family HMM PF03245; bacteriophage lysis protein 847313..847750 Escherichia coli E24377A 5589826 YP_001461954.1 CDS EcE24377A_0829 NC_009801.1 847955 848476 D identified by match to protein family HMM PF04383; KilA domain-containing protein 847955..848476 Escherichia coli E24377A 5590100 YP_001461955.1 CDS EcE24377A_0830 NC_009801.1 849632 849775 D identified by glimmer; hypothetical protein 849632..849775 Escherichia coli E24377A 5586678 YP_001461956.1 CDS EcE24377A_0831 NC_009801.1 849915 850460 D identified by match to protein family HMM PF07471; phage DNA packaging protein Nu1 849915..850460 Escherichia coli E24377A 5586748 YP_001461957.1 CDS EcE24377A_0832 NC_009801.1 850435 852024 D identified by match to protein family HMM PF05876; phage terminase large subunit (GpA) 850435..852024 Escherichia coli E24377A 5590205 YP_001461958.1 CDS EcE24377A_0833 NC_009801.1 852030 852875 D identified by match to protein family HMM PF03335; match to protein family HMM PF07484; phage tail collar domain-containing protein 852030..852875 Escherichia coli E24377A 5588856 YP_001461959.1 CDS EcE24377A_0834 NC_009801.1 852875 853459 D identified by similarity to SP:P03740; match to protein family HMM PF02413; tail fiber assembly protein 852875..853459 Escherichia coli E24377A 5590615 YP_001461960.1 CDS EcE24377A_0835 NC_009801.1 853533 854864 R identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase complement(853533..854864) Escherichia coli E24377A 5588160 YP_001461961.1 CDS EcE24377A_0836 NC_009801.1 855610 856086 R YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein complement(855610..856086) Escherichia coli E24377A 5589227 YP_001461962.1 CDS bioA NC_009801.1 856145 857434 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(856145..857434) Escherichia coli E24377A 5587821 YP_001461963.1 CDS bioB NC_009801.1 857521 858561 D identified by similarity to SP:P12996; match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR00433; biotin synthase 857521..858561 Escherichia coli E24377A 5590024 YP_001461964.1 CDS bioF NC_009801.1 858558 859712 D catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 858558..859712 Escherichia coli E24377A 5589604 YP_001461965.1 CDS bioC NC_009801.1 859699 860454 D methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 859699..860454 Escherichia coli E24377A 5589824 YP_001461966.1 CDS bioD NC_009801.1 860447 861124 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 860447..861124 Escherichia coli E24377A 5587098 YP_001461967.1 CDS uvrB NC_009801.1 861703 863724 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 861703..863724 Escherichia coli E24377A 5586905 YP_001461968.1 CDS EcE24377A_0843 NC_009801.1 863916 864824 R identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826; hypothetical protein complement(863916..864824) Escherichia coli E24377A 5587108 YP_001461969.1 CDS moaA NC_009801.1 865221 866210 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 865221..866210 Escherichia coli E24377A 5588116 YP_001461970.1 CDS moaB NC_009801.1 866232 866744 D identified by similarity to SP:P30746; match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR02667; molybdenum cofactor biosynthesis protein B 866232..866744 Escherichia coli E24377A 5590274 YP_001461971.1 CDS moaC NC_009801.1 866747 867232 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 866747..867232 Escherichia coli E24377A 5586738 YP_001461972.1 CDS moaD NC_009801.1 867225 867470 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 867225..867470 Escherichia coli E24377A 5590730 YP_001461973.1 CDS moaE NC_009801.1 867472 867924 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 867472..867924 Escherichia coli E24377A 5586195 YP_001461974.1 CDS EcE24377A_0849 NC_009801.1 868061 868765 D identified by match to protein family HMM PF01027; hypothetical protein 868061..868765 Escherichia coli E24377A 5587378 YP_001461975.1 CDS EcE24377A_0850 NC_009801.1 868857 868961 R identified by glimmer; hypothetical protein complement(868857..868961) Escherichia coli E24377A 5588522 YP_001461976.1 CDS EcE24377A_0851 NC_009801.1 868970 869683 D ybhM; identified by match to protein family HMM PF01027; hypothetical protein 868970..869683 Escherichia coli E24377A 5590073 YP_001461977.1 CDS EcE24377A_0852 NC_009801.1 869719 870675 R hypothetical protein complement(869719..870675) Escherichia coli E24377A 5587210 YP_001461978.1 CDS EcE24377A_0853 NC_009801.1 870675 871916 R identified by match to protein family HMM PF00614; cardiolipin synthase 2 complement(870675..871916) Escherichia coli E24377A 5589197 YP_001461979.1 CDS EcE24377A_0855 NC_009801.1 871891 872010 D identified by glimmer; hypothetical protein 871891..872010 Escherichia coli E24377A 5589570 YP_001461980.1 CDS EcE24377A_0854 NC_009801.1 871913 872674 R identified by match to protein family HMM PF03372; hypothetical protein complement(871913..872674) Escherichia coli E24377A 5586571 YP_001461981.1 CDS EcE24377A_0857 NC_009801.1 872807 873217 D hypothetical protein 872807..873217 Escherichia coli E24377A 5590630 YP_001461982.1 CDS EcE24377A_0856 NC_009801.1 873179 874285 R identified by match to protein family HMM PF01061; ABC-2 type transporter permease complement(873179..874285) Escherichia coli E24377A 5587926 YP_001461983.1 CDS EcE24377A_0858 NC_009801.1 874296 875429 R identified by match to protein family HMM PF01061; ABC-2 type transporter permease complement(874296..875429) Escherichia coli E24377A 5589289 YP_001461984.1 CDS EcE24377A_0859 NC_009801.1 875422 877158 R identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(875422..877158) Escherichia coli E24377A 5587273 YP_001461985.1 CDS EcE24377A_0860 NC_009801.1 877151 878146 R identified by match to protein family HMM PF00529; hypothetical protein complement(877151..878146) Escherichia coli E24377A 5588954 YP_001461986.1 CDS EcE24377A_0861 NC_009801.1 878149 878820 R identified by match to protein family HMM PF00440; match to protein family HMM PF09209; DNA-binding transcriptional regulator complement(878149..878820) Escherichia coli E24377A 5587991 YP_001461987.1 CDS EcE24377A_0862 NC_009801.1 879049 880413 D this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 879049..880413 Escherichia coli E24377A 5588318 YP_001461988.1 CDS EcE24377A_0863 NC_009801.1 880418 880579 R identified by glimmer; hypothetical protein complement(880418..880579) Escherichia coli E24377A 5588120 YP_001461989.1 CDS EcE24377A_0864 NC_009801.1 880420 880515 D identified by glimmer; hypothetical protein 880420..880515 Escherichia coli E24377A 5587679 YP_001461990.1 CDS EcE24377A_0865 NC_009801.1 880645 881127 R identified by similarity to GB:CAD72180.1; match to protein family HMM PF08719; match to protein family HMM TIGR02464; hypothetical protein complement(880645..881127) Escherichia coli E24377A 5589394 YP_001461991.1 CDS dinG NC_009801.1 881247 883397 D helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 881247..883397 Escherichia coli E24377A 5588821 YP_001461992.1 CDS EcE24377A_0867 NC_009801.1 883425 884387 D identified by match to protein family HMM PF02885; glycosyl transferase family protein 883425..884387 Escherichia coli E24377A 5590605 YP_001461993.1 CDS EcE24377A_0868 NC_009801.1 884425 884529 R identified by glimmer; hypothetical protein complement(884425..884529) Escherichia coli E24377A 5590173 YP_001461994.1 CDS EcE24377A_0869 NC_009801.1 884528 885613 D identified by similarity to PDB:2G8Y_A; match to protein family HMM PF02615; hypothetical protein 884528..885613 Escherichia coli E24377A 5588321 YP_001461995.1 CDS EcE24377A_0870 NC_009801.1 885842 886102 R identified by match to protein family HMM PF07338; hypothetical protein complement(885842..886102) Escherichia coli E24377A 5590525 YP_001461996.1 CDS EcE24377A_0871 NC_009801.1 886367 886633 R identified by match to protein family HMM PF01258; hypothetical protein complement(886367..886633) Escherichia coli E24377A 5588523 YP_001461997.1 CDS EcE24377A_0872 NC_009801.1 886707 887384 R identified by match to protein family HMM PF03171; hydroxylase complement(886707..887384) Escherichia coli E24377A 5589563 YP_001461998.1 CDS fiu NC_009801.1 887426 889708 R Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu complement(887426..889708) Escherichia coli E24377A 5589018 YP_001461999.1 CDS EcE24377A_0874 NC_009801.1 889692 889796 D identified by glimmer; hypothetical protein 889692..889796 Escherichia coli E24377A 5590588 YP_001462000.1 CDS EcE24377A_0875 NC_009801.1 889973 890377 R identified by match to protein family HMM PF07338; hypothetical protein complement(889973..890377) Escherichia coli E24377A 5588487 YP_001462001.1 CDS EcE24377A_0877 NC_009801.1 890428 891435 D identified by match to protein family HMM PF05971; SAM-dependent methyltransferase 890428..891435 Escherichia coli E24377A 5588793 YP_001462002.1 CDS EcE24377A_0876 NC_009801.1 891432 893657 R identified by match to protein family HMM PF00924; hypothetical protein complement(891432..893657) Escherichia coli E24377A 5588938 YP_001462003.1 CDS glnQ NC_009801.1 893774 894496 R similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein complement(893774..894496) Escherichia coli E24377A 5588046 YP_001462004.1 CDS glnP NC_009801.1 894493 895152 R similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease complement(894493..895152) Escherichia coli E24377A 5586145 YP_001462005.1 CDS glnH NC_009801.1 895291 896037 R similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein complement(895291..896037) Escherichia coli E24377A 5586697 YP_001462006.1 CDS dps NC_009801.1 896441 896944 R binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps complement(896441..896944) Escherichia coli E24377A 5588356 YP_001462007.1 CDS EcE24377A_0882 NC_009801.1 897114 897212 R identified by glimmer; hypothetical protein complement(897114..897212) Escherichia coli E24377A 5589800 YP_001462008.1 CDS rhtA NC_009801.1 897243 898130 R identified by similarity to SP:P0AA67; match to protein family HMM PF00892; threonine and homoserine efflux system complement(897243..898130) Escherichia coli E24377A 5586559 YP_001462009.1 CDS ompX NC_009801.1 898483 898998 D OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 898483..898998 Escherichia coli E24377A 5588532 YP_001462010.1 CDS EcE24377A_0885 NC_009801.1 899047 900630 R identified by match to protein family HMM PF00884; sulfatase complement(899047..900630) Escherichia coli E24377A 5587604 YP_001462011.1 CDS EcE24377A_0886 NC_009801.1 900902 901030 R hypothetical protein complement(900902..901030) Escherichia coli E24377A 5588217 YP_001462012.1 CDS mntR NC_009801.1 901216 901683 D Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 901216..901683 Escherichia coli E24377A 5588343 YP_001462013.1 CDS EcE24377A_0888 NC_009801.1 901680 902798 D identified by match to protein family HMM PF03600; citrate transporter family protein 901680..902798 Escherichia coli E24377A 5587868 YP_001462014.1 CDS ybiS NC_009801.1 902857 903777 R identified by similarity to SP:P0AAX8; match to protein family HMM PF03734; hypothetical protein complement(902857..903777) Escherichia coli E24377A 5588180 YP_001462015.1 CDS EcE24377A_0890 NC_009801.1 903996 905588 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 903996..905588 Escherichia coli E24377A 5588690 YP_001462016.1 CDS EcE24377A_0891 NC_009801.1 905867 906847 D identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 905867..906847 Escherichia coli E24377A 5588267 YP_001462017.1 CDS EcE24377A_0892 NC_009801.1 907108 908373 R identified by match to protein family HMM PF07350; hypothetical protein complement(907108..908373) Escherichia coli E24377A 5586585 YP_001462018.1 CDS supH NC_009801.1 908525 909340 R identified by similarity to SP:P75792; match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; sugar phosphatase SupH complement(908525..909340) Escherichia coli E24377A 5588841 YP_001462019.1 CDS EcE24377A_0894 NC_009801.1 909486 911918 R identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774; formate C-acetyltransferas complement(909486..911918) Escherichia coli E24377A 5586411 YP_001462020.1 CDS EcE24377A_0895 NC_009801.1 911924 912823 R identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494; glycyl-radical activating family protein complement(911924..912823) Escherichia coli E24377A 5590306 YP_001462021.1 CDS fsaA NC_009801.1 912954 913616 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 912954..913616 Escherichia coli E24377A 5587730 YP_001462022.1 CDS moeB NC_009801.1 913795 914544 R ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB complement(913795..914544) Escherichia coli E24377A 5587226 YP_001462023.1 CDS moeA NC_009801.1 914544 915779 R is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA complement(914544..915779) Escherichia coli E24377A 5588583 YP_001462024.1 CDS EcE24377A_0899 NC_009801.1 915983 916948 D identified by similarity to SP:P37595; match to protein family HMM PF01112; L-asparaginase 915983..916948 Escherichia coli E24377A 5590459 YP_001462025.1 CDS gsiA NC_009801.1 916935 918806 D with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 916935..918806 Escherichia coli E24377A 5588302 YP_001462026.1 CDS gsiB NC_009801.1 918826 920364 D identified by similarity to SP:P75797; match to protein family HMM PF00496; glutathione ABC transporter periplasmic glutathione-binding protein GsiB 918826..920364 Escherichia coli E24377A 5588440 YP_001462027.1 CDS gsiC NC_009801.1 920382 921302 D identified by similarity to SP:P75798; match to protein family HMM PF00528; glutathione ABC transporter permease GsiC 920382..921302 Escherichia coli E24377A 5588866 YP_001462028.1 CDS gsiD NC_009801.1 921305 922216 D identified by similarity to SP:P75799; match to protein family HMM PF00528; glutathione ABC transporter permease GsiD 921305..922216 Escherichia coli E24377A 5588830 YP_001462029.1 CDS EcE24377A_0904 NC_009801.1 922394 924742 D identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase domain-containing protein 922394..924742 Escherichia coli E24377A 5588903 YP_001462030.1 CDS EcE24377A_0905 NC_009801.1 924750 926078 D identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 924750..926078 Escherichia coli E24377A 5590110 YP_001462031.1 CDS rimO NC_009801.1 926125 927450 R catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase complement(926125..927450) Escherichia coli E24377A 5586515 YP_001462032.1 CDS bssR NC_009801.1 927630 928046 D BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 927630..928046 Escherichia coli E24377A 5590433 YP_001462033.1 CDS yliI NC_009801.1 928157 929272 D identified by similarity to SP:P75804; match to protein family HMM PF07995; aldose sugar dehydrogenase yliI 928157..929272 Escherichia coli E24377A 5590590 YP_001462034.1 CDS EcE24377A_0908 NC_009801.1 929269 929895 R identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase complement(929269..929895) Escherichia coli E24377A 5587964 YP_001462035.1 CDS dacC NC_009801.1 930142 931344 D penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 930142..931344 Escherichia coli E24377A 5589168 YP_001462036.1 CDS deoR NC_009801.1 931391 932149 R identified by similarity to SP:P0ACK5; match to protein family HMM PF00455; match to protein family HMM PF08220; DNA-binding transcriptional repressor DeoR complement(931391..932149) Escherichia coli E24377A 5590668 YP_001462037.1 CDS EcE24377A_0912 NC_009801.1 932207 932803 R identified by match to protein family HMM PF01569; undecaprenyl pyrophosphate phosphatase complement(932207..932803) Escherichia coli E24377A 5588876 YP_001462038.1 CDS EcE24377A_0913 NC_009801.1 932996 933103 D identified by glimmer; hypothetical protein 932996..933103 Escherichia coli E24377A 5586030 YP_001462039.1 CDS mdfA NC_009801.1 933088 934320 D identified by match to protein family HMM PF07690; multidrug translocase MdfA 933088..934320 Escherichia coli E24377A 5588247 YP_001462040.1 CDS EcE24377A_0915 NC_009801.1 934360 934638 R hypothetical protein complement(934360..934638) Escherichia coli E24377A 5587537 YP_001462041.1 CDS ybjI NC_009801.1 934730 935545 R identified by similarity to SP:P75809; match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; phosphatase YbjI complement(934730..935545) Escherichia coli E24377A 5586294 YP_001462042.1 CDS EcE24377A_0917 NC_009801.1 935545 936753 R identified by match to protein family HMM PF07690; major facilitator transporter complement(935545..936753) Escherichia coli E24377A 5587816 YP_001462043.1 CDS EcE24377A_0918 NC_009801.1 936837 937373 D identified by match to protein family HMM PF00440; TetR family transcriptional regulator 936837..937373 Escherichia coli E24377A 5586795 YP_001462044.1 CDS EcE24377A_0919 NC_009801.1 937548 939233 R identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625; hypothetical protein complement(937548..939233) Escherichia coli E24377A 5585972 YP_001462045.1 CDS EcE24377A_0920 NC_009801.1 939503 939880 D hypothetical protein 939503..939880 Escherichia coli E24377A 5586040 YP_001462046.1 CDS grxA NC_009801.1 939910 940167 R functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin complement(939910..940167) Escherichia coli E24377A 5586965 YP_001462047.1 CDS EcE24377A_0922 NC_009801.1 940327 940614 D YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 940327..940614 Escherichia coli E24377A 5589250 YP_001462048.1 CDS nfsA NC_009801.1 940598 941320 D NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 940598..941320 Escherichia coli E24377A 5589926 YP_001462049.1 CDS rimK NC_009801.1 941381 942283 D responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 941381..942283 Escherichia coli E24377A 5588152 YP_001462050.1 CDS EcE24377A_0925 NC_009801.1 942323 942847 D hypothetical protein 942323..942847 Escherichia coli E24377A 5590228 YP_001462051.1 CDS potF NC_009801.1 943198 944310 D identified by match to protein family HMM PF01547; putrescine ABC transporter periplasmic-binding protein 943198..944310 Escherichia coli E24377A 5586117 YP_001462052.1 CDS potG NC_009801.1 944405 945538 D part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 944405..945538 Escherichia coli E24377A 5585978 YP_001462053.1 CDS potH NC_009801.1 945548 946501 D identified by match to protein family HMM PF00528; putrescine ABC transporter membrane protein 945548..946501 Escherichia coli E24377A 5587009 YP_001462054.1 CDS potI NC_009801.1 946498 947343 D identified by match to protein family HMM PF00528; putrescine ABC transporter membrane protein 946498..947343 Escherichia coli E24377A 5588344 YP_001462055.1 CDS EcE24377A_0930 NC_009801.1 947403 947891 D hypothetical protein 947403..947891 Escherichia coli E24377A 5590468 YP_001462056.1 CDS rumB NC_009801.1 947932 949059 D RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 947932..949059 Escherichia coli E24377A 5587143 YP_001462057.1 CDS EcE24377A_0933 NC_009801.1 949071 949259 D identified by glimmer; hypothetical protein 949071..949259 Escherichia coli E24377A 5589317 YP_001462058.1 CDS artJ NC_009801.1 949234 949965 R identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096; arginine ABC transporter substrate-binding protein complement(949234..949965) Escherichia coli E24377A 5589222 YP_001462059.1 CDS artM NC_009801.1 950256 950924 R with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM complement(950256..950924) Escherichia coli E24377A 5585966 YP_001462060.1 CDS artQ NC_009801.1 950924 951640 R with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ complement(950924..951640) Escherichia coli E24377A 5588745 YP_001462061.1 CDS artI NC_009801.1 951647 952378 R identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096; arginine ABC transporter substrate-binding protein complement(951647..952378) Escherichia coli E24377A 5588428 YP_001462062.1 CDS artP NC_009801.1 952396 953124 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit complement(952396..953124) Escherichia coli E24377A 5587245 YP_001462063.1 CDS EcE24377A_0938 NC_009801.1 953342 953857 R induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein complement(953342..953857) Escherichia coli E24377A 5589605 YP_001462064.1 CDS EcE24377A_0939 NC_009801.1 953983 954306 D identified by match to protein family HMM PF01906; hypothetical protein 953983..954306 Escherichia coli E24377A 5586415 YP_001462065.1 CDS amiD NC_009801.1 954303 955133 D identified by similarity to SP:P75820; match to protein family HMM PF01510; N-acetylmuramoyl-L-alanine amidase 954303..955133 Escherichia coli E24377A 5588928 YP_001462066.1 CDS EcE24377A_0940 NC_009801.1 955130 956179 R identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993; NAD-dependent epimerase/dehydratase complement(955130..956179) Escherichia coli E24377A 5589963 YP_001462067.1 CDS EcE24377A_0942 NC_009801.1 956242 957672 R identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF05368; NAD dependent epimerase/dehydratase complement(956242..957672) Escherichia coli E24377A 5588708 YP_001462068.1 CDS ltaE NC_009801.1 957683 958684 R low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase complement(957683..958684) Escherichia coli E24377A 5588622 YP_001462069.1 CDS poxB NC_009801.1 958721 960439 R catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase complement(958721..960439) Escherichia coli E24377A 5588123 YP_001462070.1 CDS hcr NC_009801.1 960572 961540 R identified by similarity to SP:P75824; match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; HCP oxidoreductase complement(960572..961540) Escherichia coli E24377A 5590111 YP_001462071.1 CDS hcp NC_009801.1 961552 963204 R catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase complement(961552..963204) Escherichia coli E24377A 5586715 YP_001462072.1 CDS EcE24377A_0947 NC_009801.1 963348 964247 R identified by match to protein family HMM PF03956; hypothetical protein complement(963348..964247) Escherichia coli E24377A 5586130 YP_001462073.1 CDS aqpZ NC_009801.1 964704 965399 R porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z complement(964704..965399) Escherichia coli E24377A 5586768 YP_001462074.1 CDS EcE24377A_0950 NC_009801.1 965825 967483 D identified by similarity to GB:ABG68906.1; hypothetical protein 965825..967483 Escherichia coli E24377A 5589258 YP_001462075.1 CDS EcE24377A_0949 NC_009801.1 967480 968472 R identified by match to protein family HMM PF04393; hypothetical protein complement(967480..968472) Escherichia coli E24377A 5586473 YP_001462076.1 CDS macA NC_009801.1 968587 969702 D confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 968587..969702 Escherichia coli E24377A 5588375 YP_001462077.1 CDS cspD NC_009801.1 971717 971941 R inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD complement(971717..971941) Escherichia coli E24377A 5588087 YP_001462078.1 CDS clpS NC_009801.1 972264 972584 D involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 972264..972584 Escherichia coli E24377A 5590482 YP_001462079.1 CDS clpA NC_009801.1 972615 974891 D ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 972615..974891 Escherichia coli E24377A 5589455 YP_001462080.1 CDS infA NC_009801.1 975635 975853 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(975635..975853) Escherichia coli E24377A 5589052 YP_001462081.1 CDS aat NC_009801.1 976138 976842 R leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase complement(976138..976842) Escherichia coli E24377A 5586913 YP_001462082.1 CDS cudC NC_009801.1 976884 978605 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(976884..978605) Escherichia coli E24377A 5587184 YP_001462083.1 CDS cydD NC_009801.1 978606 980372 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(978606..980372) Escherichia coli E24377A 5586360 YP_001462084.1 CDS EcE24377A_0961 NC_009801.1 979169 979261 D identified by glimmer; hypothetical protein 979169..979261 Escherichia coli E24377A 5586186 YP_001462085.1 CDS trxB NC_009801.1 980495 981460 R catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase complement(980495..981460) Escherichia coli E24377A 5590238 YP_001462086.1 CDS EcE24377A_0963 NC_009801.1 981529 981642 D identified by glimmer; hypothetical protein 981529..981642 Escherichia coli E24377A 5587632 YP_001462087.1 CDS lrp NC_009801.1 982005 982499 D mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 982005..982499 Escherichia coli E24377A 5587257 YP_001462088.1 CDS ftsK NC_009801.1 982634 986740 D DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 982634..986740 Escherichia coli E24377A 5587947 YP_001462089.1 CDS lolA NC_009801.1 986895 987506 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 986895..987506 Escherichia coli E24377A 5588933 YP_001462090.1 CDS EcE24377A_0967 NC_009801.1 987517 988860 D identified by similarity to SP:P0AAZ4; match to protein family HMM PF00004; recombination factor protein RarA 987517..988860 Escherichia coli E24377A 5589371 YP_001462091.1 CDS serS NC_009801.1 988951 990243 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 988951..990243 Escherichia coli E24377A 5590561 YP_001462092.1 CDS dmsA NC_009801.1 990482 992926 D identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166; anaerobic dimethyl sulfoxide reductase, A subunit 990482..992926 Escherichia coli E24377A 5589261 YP_001462093.1 CDS dmsB1 NC_009801.1 992937 993554 D identified by similarity to SP:P18776; match to protein family HMM PF00037; match to protein family HMM TIGR02951; dimethylsulfoxide reductase subunit B 992937..993554 Escherichia coli E24377A 5588724 YP_001462094.1 CDS EcE24377A_0970 NC_009801.1 993132 994037 R identified by glimmer; hypothetical protein complement(993132..994037) Escherichia coli E24377A 5588204 YP_001462095.1 CDS dmsC1 NC_009801.1 993556 994419 D identified by similarity to SP:P18777; match to protein family HMM PF04976; anaerobic dimethyl sulfoxide reductase subunit C 993556..994419 Escherichia coli E24377A 5590818 YP_001462096.1 CDS EcE24377A_0973 NC_009801.1 994455 995081 R identified by match to protein family HMM PF00857; isochorismatase hydrolase complement(994455..995081) Escherichia coli E24377A 5589640 YP_001462097.1 CDS EcE24377A_0974 NC_009801.1 995237 995365 R identified by glimmer; hypothetical protein complement(995237..995365) Escherichia coli E24377A 5588953 YP_001462098.1 CDS EcE24377A_0975 NC_009801.1 995396 996544 D identified by match to protein family HMM PF07690; MFS family transporter protein 995396..996544 Escherichia coli E24377A 5586123 YP_001462099.1 CDS EcE24377A_0976 NC_009801.1 996562 998184 D identified by match to protein family HMM PF00324; amino acid permease 996562..998184 Escherichia coli E24377A 5589918 YP_001462100.1 CDS EcE24377A_0977 NC_009801.1 998185 999093 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(998185..999093) Escherichia coli E24377A 5589865 YP_001462101.1 CDS EcE24377A_0978 NC_009801.1 998188 998301 D identified by glimmer; hypothetical protein 998188..998301 Escherichia coli E24377A 5588495 YP_001462102.1 CDS EcE24377A_0979 NC_009801.1 999193 999783 D identified by match to protein family HMM PF02525; match to protein family HMM PF03358; hypothetical protein 999193..999783 Escherichia coli E24377A 5588567 YP_001462103.1 CDS pflA NC_009801.1 999865 1000662 R activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(999865..1000662) Escherichia coli E24377A 5586370 YP_001462104.1 CDS EcE24377A_0981 NC_009801.1 1000694 1001689 R identified by match to protein family HMM PF00589; phage integrase site specific recombinase complement(1000694..1001689) Escherichia coli E24377A 5587204 YP_001462105.1 CDS cox NC_009801.1 1002191 1002547 D identified by similarity to SP:P07695; phage regulatory protein 1002191..1002547 Escherichia coli E24377A 5590852 YP_001462106.1 CDS EcE24377A_0983 NC_009801.1 1002725 1003225 D identified by similarity to SP:P07696; replication gene B protein 1002725..1003225 Escherichia coli E24377A 5588896 YP_001462107.1 CDS EcE24377A_0984 NC_009801.1 1003256 1003513 D identified by similarity to GB:AAL21618.1; hypothetical protein 1003256..1003513 Escherichia coli E24377A 5589842 YP_001462108.1 CDS EcE24377A_0985 NC_009801.1 1003513 1003815 D hypothetical protein 1003513..1003815 Escherichia coli E24377A 5587472 YP_001462109.1 CDS EcE24377A_0986 NC_009801.1 1003815 1004039 D identified by match to protein family HMM PF01258; match to protein family HMM TIGR02419; C4-type zinc finger DksA/TraR family protein 1003815..1004039 Escherichia coli E24377A 5586233 YP_001462110.1 CDS EcE24377A_0987 NC_009801.1 1004036 1004311 D hypothetical protein 1004036..1004311 Escherichia coli E24377A 5587715 YP_001462111.1 CDS gpA NC_009801.1 1004301 1006577 D identified by similarity to SP:Q06419; match to protein family HMM PF05840; replication gene A protein 1004301..1006577 Escherichia coli E24377A 5587824 YP_001462112.1 CDS EcE24377A_0989 NC_009801.1 1007691 1008992 D identified by similarity to GB:ABB41600.1; hypothetical protein 1007691..1008992 Escherichia coli E24377A 5589308 YP_001462113.1 CDS EcE24377A_0990 NC_009801.1 1009542 1010084 R identified by match to protein family HMM PF04860; PBSX family phage portal protein complement(1009542..1010084) Escherichia coli E24377A 5588667 YP_001462114.1 CDS EcE24377A_0993 NC_009801.1 1010333 1011418 D hypothetical protein 1010333..1011418 Escherichia coli E24377A 5588914 YP_001462115.1 CDS EcE24377A_0994 NC_009801.1 1011492 1012664 D identified by similarity to SP:P15025; match to protein family HMM PF00665; IS21 family transposase 1011492..1012664 Escherichia coli E24377A 5587491 YP_001462116.1 CDS EcE24377A_0995 NC_009801.1 1012664 1013458 D identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein 1012664..1013458 Escherichia coli E24377A 5590535 YP_001462117.1 CDS EcE24377A_0996 NC_009801.1 1013530 1014909 D hypothetical protein 1013530..1014909 Escherichia coli E24377A 5588794 YP_001462118.1 CDS gpU NC_009801.1 1014924 1015403 D identified by match to protein family HMM PF06995; phage protein gpU 1014924..1015403 Escherichia coli E24377A 5586765 YP_001462119.1 CDS EcE24377A_0998 NC_009801.1 1015403 1016566 D identified by match to protein family HMM PF05954; phage late control gene D protein 1015403..1016566 Escherichia coli E24377A 5590337 YP_001462120.1 CDS EcE24377A_0999 NC_009801.1 1016648 1016866 D in E. coli K-12 this is in prophage P2 remnant; DNA-binding transcriptional regulator 1016648..1016866 Escherichia coli E24377A 5587631 YP_001462121.1 CDS pflB2 NC_009801.1 1017186 1019468 R identified by similarity to SP:P09373; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; formate acetyltransferase complement(1017186..1019468) Escherichia coli E24377A 5590867 YP_001462122.1 CDS EcE24377A_1001 NC_009801.1 1019523 1020380 R identified by match to protein family HMM PF01226; match to protein family HMM TIGR00790; formate transporter complement(1019523..1020380) Escherichia coli E24377A 5590721 YP_001462123.1 CDS EcE24377A_1002 NC_009801.1 1020786 1022546 R identified by similarity to GB:AAP16417.1; match to protein family HMM PF02624; match to protein family HMM TIGR00702; hypothetical protein complement(1020786..1022546) Escherichia coli E24377A 5590752 YP_001462124.1 CDS EcE24377A_1003 NC_009801.1 1022676 1023368 D identified by match to protein family HMM PF04239; hypothetical protein 1022676..1023368 Escherichia coli E24377A 5589043 YP_001462125.1 CDS serC NC_009801.1 1023567 1024655 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1023567..1024655 Escherichia coli E24377A 5588588 YP_001462126.1 CDS aroA NC_009801.1 1024726 1026009 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1024726..1026009 Escherichia coli E24377A 5590603 YP_001462127.1 CDS EcE24377A_1006 NC_009801.1 1026178 1026942 D ycaL; identified by match to protein family HMM PF01435; M48B family peptidase 1026178..1026942 Escherichia coli E24377A 5588988 YP_001462128.1 CDS cmk NC_009801.1 1027115 1027798 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1027115..1027798 Escherichia coli E24377A 5587490 YP_001462129.1 CDS rpsA NC_009801.1 1027909 1029582 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1027909..1029582 Escherichia coli E24377A 5589647 YP_001462130.1 CDS ihfB NC_009801.1 1029742 1030026 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1029742..1030026 Escherichia coli E24377A 5586580 YP_001462131.1 CDS EcE24377A_1011 NC_009801.1 1030233 1032497 D ycaI; identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361; hypothetical protein 1030233..1032497 Escherichia coli E24377A 5587004 YP_001462132.1 CDS msbA NC_009801.1 1032534 1034282 D involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding protein/permease 1032534..1034282 Escherichia coli E24377A 5586862 YP_001462133.1 CDS lpxK NC_009801.1 1034279 1035265 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1034279..1035265 Escherichia coli E24377A 5589730 YP_001462134.1 CDS EcE24377A_1014 NC_009801.1 1035302 1036534 D identified by match to protein family HMM PF06224; hypothetical protein 1035302..1036534 Escherichia coli E24377A 5586525 YP_001462135.1 CDS EcE24377A_1015 NC_009801.1 1036586 1036768 D identified by similarity to GB:AAX64850.1; match to protein family HMM PF03966; hypothetical protein 1036586..1036768 Escherichia coli E24377A 5586854 YP_001462136.1 CDS kdsB NC_009801.1 1036765 1037511 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1036765..1037511 Escherichia coli E24377A 5587158 YP_001462137.1 CDS EcE24377A_1018 NC_009801.1 1037665 1038558 D hypothetical protein 1037665..1038558 Escherichia coli E24377A 5585916 YP_001462138.1 CDS EcE24377A_1017 NC_009801.1 1038535 1039314 R identified by match to protein family HMM PF02698; hypothetical protein complement(1038535..1039314) Escherichia coli E24377A 5589433 YP_001462139.1 CDS EcE24377A_1019 NC_009801.1 1039217 1039381 R identified by glimmer; hypothetical protein complement(1039217..1039381) Escherichia coli E24377A 5587042 YP_001462140.1 CDS smtA NC_009801.1 1039450 1040235 D involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 1039450..1040235 Escherichia coli E24377A 5589485 YP_001462141.1 CDS mukF NC_009801.1 1040232 1041554 D acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1040232..1041554 Escherichia coli E24377A 5589622 YP_001462142.1 CDS mukE NC_009801.1 1041535 1042239 D acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1041535..1042239 Escherichia coli E24377A 5588327 YP_001462143.1 CDS mukB NC_009801.1 1042239 1046699 D SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1042239..1046699 Escherichia coli E24377A 5587518 YP_001462144.1 CDS EcE24377A_1024 NC_009801.1 1046960 1048807 D identified by match to protein family HMM PF01471; hypothetical protein 1046960..1048807 Escherichia coli E24377A 5587766 YP_001462145.1 CDS EcE24377A_1025 NC_009801.1 1048988 1049536 D identified by match to protein family HMM PF05951; match to protein family HMM PF08291; match to protein family HMM TIGR01409; Tat pathway signal sequence domain-containing protein 1048988..1049536 Escherichia coli E24377A 5587304 YP_001462146.1 CDS EcE24377A_1026 NC_009801.1 1049563 1050210 D identified by match to protein family HMM PF00753; metallo-beta-lactamase 1049563..1050210 Escherichia coli E24377A 5587720 YP_001462147.1 CDS aspC NC_009801.1 1050432 1051622 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(1050432..1051622) Escherichia coli E24377A 5588139 YP_001462148.1 CDS EcE24377A_1028 NC_009801.1 1051696 1051794 R identified by glimmer; hypothetical protein complement(1051696..1051794) Escherichia coli E24377A 5589387 YP_001462149.1 CDS ompF NC_009801.1 1051807 1052895 R outer membrane porin F; 1a; Ia; b; outer membrane protein F complement(1051807..1052895) Escherichia coli E24377A 5586595 YP_001462150.1 CDS asnC NC_009801.1 1053497 1054897 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(1053497..1054897) Escherichia coli E24377A 5587779 YP_001462151.1 CDS pncB NC_009801.1 1055066 1056268 R catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(1055066..1056268) Escherichia coli E24377A 5588986 YP_001462152.1 CDS pepN NC_009801.1 1056534 1059146 D identified by match to protein family HMM PF01433; match to protein family HMM TIGR02414; aminopeptidase 1056534..1059146 Escherichia coli E24377A 5586539 YP_001462153.1 CDS EcE24377A_1034 NC_009801.1 1059162 1059278 D identified by glimmer; hypothetical protein 1059162..1059278 Escherichia coli E24377A 5590194 YP_001462154.1 CDS ssuB NC_009801.1 1059353 1060120 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit complement(1059353..1060120) Escherichia coli E24377A 5586484 YP_001462155.1 CDS ssuC NC_009801.1 1060117 1060908 R part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease subunit complement(1060117..1060908) Escherichia coli E24377A 5590695 YP_001462156.1 CDS ssuD NC_009801.1 1060919 1062064 R catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase complement(1060919..1062064) Escherichia coli E24377A 5588937 YP_001462157.1 CDS EcE24377A_1038 NC_009801.1 1062302 1063027 R hypothetical protein complement(1062302..1063027) Escherichia coli E24377A 5588242 YP_001462158.1 CDS EcE24377A_1039 NC_009801.1 1063917 1064831 D hypothetical protein 1063917..1064831 Escherichia coli E24377A 5588291 YP_001462159.1 CDS EcE24377A_1040 NC_009801.1 1064834 1065367 D identified by match to protein family HMM PF02413; hypothetical protein 1064834..1065367 Escherichia coli E24377A 5588448 YP_001462160.1 CDS gpG NC_009801.1 1065396 1065923 R identified by match to protein family HMM PF02413; tail fiber assembly protein complement(1065396..1065923) Escherichia coli E24377A 5586796 YP_001462161.1 CDS EcE24377A_1042 NC_009801.1 1065925 1067334 R identified by match to protein family HMM PF03406; phage tail fiber protein complement(1065925..1067334) Escherichia coli E24377A 5586406 YP_001462162.1 CDS EcE24377A_1043 NC_009801.1 1067334 1067876 R hypothetical protein complement(1067334..1067876) Escherichia coli E24377A 5587785 YP_001462163.1 CDS EcE24377A_1044 NC_009801.1 1067867 1068949 R identified by match to protein family HMM PF04865; baseplate assembly protein J complement(1067867..1068949) Escherichia coli E24377A 5586977 YP_001462164.1 CDS EcE24377A_1045 NC_009801.1 1068950 1069387 R identified by match to protein family HMM PF07409; phage protein GP46 complement(1068950..1069387) Escherichia coli E24377A 5587165 YP_001462165.1 CDS EcE24377A_1046 NC_009801.1 1069384 1069977 R identified by match to protein family HMM PF06890; match to protein family HMM TIGR01644; phage baseplate assembly protein V complement(1069384..1069977) Escherichia coli E24377A 5590723 YP_001462166.1 CDS EcE24377A_1047 NC_009801.1 1069965 1071104 R identified by match to protein family HMM PF06893; bacteriophage Mu P protein complement(1069965..1071104) Escherichia coli E24377A 5588683 YP_001462167.1 CDS EcE24377A_1049 NC_009801.1 1071486 1073474 R identified by similarity to SP:P07636; match to protein family HMM PF02316; match to protein family HMM PF02914; match to protein family HMM PF09039; match to protein family HMM PF09299; bacteriophage Mu transposase MuA complement(1071486..1073474) Escherichia coli E24377A 5587806 YP_001462168.1 CDS EcE24377A_1050 NC_009801.1 1073889 1074413 D identified by match to protein family HMM PF02316; repressor protein 1073889..1074413 Escherichia coli E24377A 5588543 YP_001462169.1 CDS EcE24377A_1051 NC_009801.1 1074683 1075633 R identified by match to protein family HMM PF04069; match to protein family HMM TIGR01728; aliphatic sulfonate ABC transporter periplasmic substrate-binding protein complement(1074683..1075633) Escherichia coli E24377A 5588796 YP_001462170.1 CDS EcE24377A_1052 NC_009801.1 1075584 1076159 R identified by match to protein family HMM PF02525; match to protein family HMM PF03358; NAD(P)H-dependent FMN reductase complement(1075584..1076159) Escherichia coli E24377A 5589303 YP_001462171.1 CDS EcE24377A_1053 NC_009801.1 1076515 1077057 D identified by match to protein family HMM PF00419; fimbrial protein 1076515..1077057 Escherichia coli E24377A 5588923 YP_001462172.1 CDS EcE24377A_1054 NC_009801.1 1077140 1077841 D identified by match to protein family HMM PF00345; match to protein family HMM PF02753; periplasmic pilus chaperone family protein 1077140..1077841 Escherichia coli E24377A 5587586 YP_001462173.1 CDS fimD2 NC_009801.1 1077866 1080466 D identified by similarity to SP:P30130; match to protein family HMM PF00577; outer membrane usher protein fimD 1077866..1080466 Escherichia coli E24377A 5589171 YP_001462174.1 CDS EcE24377A_1056 NC_009801.1 1080457 1081527 D identified by match to protein family HMM PF00419; fimbrial protein 1080457..1081527 Escherichia coli E24377A 5590208 YP_001462175.1 CDS EcE24377A_1057 NC_009801.1 1081539 1082081 D identified by match to protein family HMM PF00419; fimbrial protein 1081539..1082081 Escherichia coli E24377A 5588967 YP_001462176.1 CDS EcE24377A_1058 NC_009801.1 1082089 1082604 D identified by match to protein family HMM PF00419; fimbrial protein 1082089..1082604 Escherichia coli E24377A 5589790 YP_001462177.1 CDS EcE24377A_1059 NC_009801.1 1082570 1083307 D identified by match to protein family HMM PF00345; match to protein family HMM PF02753; pili assembly chaperone 1082570..1083307 Escherichia coli E24377A 5589662 YP_001462178.1 CDS pyrD NC_009801.1 1083418 1084428 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1083418..1084428 Escherichia coli E24377A 5586202 YP_001462179.1 CDS EcE24377A_1062 NC_009801.1 1084566 1085144 D identified by match to protein family HMM PF07126; hypothetical protein 1084566..1085144 Escherichia coli E24377A 5586506 YP_001462180.1 CDS EcE24377A_1061 NC_009801.1 1085141 1086250 R identified by match to protein family HMM PF00111; match to protein family HMM PF03473; match to protein family HMM PF03476; MOSC domain-containing protein complement(1085141..1086250) Escherichia coli E24377A 5587032 YP_001462181.1 CDS rlmL NC_009801.1 1086494 1088602 D catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1086494..1088602 Escherichia coli E24377A 5587440 YP_001462182.1 CDS uup NC_009801.1 1088614 1090521 D Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1088614..1090521 Escherichia coli E24377A 5589055 YP_001462183.1 CDS pqiA NC_009801.1 1090651 1091904 D identified by similarity to SP:P43670; match to protein family HMM PF04403; match to protein family HMM TIGR00155; paraquat-inducible protein A 1090651..1091904 Escherichia coli E24377A 5587548 YP_001462184.1 CDS pqiB NC_009801.1 1091909 1093549 D identified by similarity to SP:P43671; match to protein family HMM PF02470; paraquat-inducible protein B 1091909..1093549 Escherichia coli E24377A 5587039 YP_001462185.1 CDS EcE24377A_1067 NC_009801.1 1093546 1094109 D identified by match to protein family HMM PF03886; hypothetical protein 1093546..1094109 Escherichia coli E24377A 5588240 YP_001462186.1 CDS fabA NC_009801.1 1094602 1095120 R catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase complement(1094602..1095120) Escherichia coli E24377A 5587702 YP_001462187.1 CDS EcE24377A_1069 NC_009801.1 1095189 1096949 R S16 family peptidase complement(1095189..1096949) Escherichia coli E24377A 5588892 YP_001462188.1 CDS EcE24377A_1070 NC_009801.1 1097135 1097587 D identified by match to protein family HMM PF06303; hypothetical protein 1097135..1097587 Escherichia coli E24377A 5588232 YP_001462189.1 CDS ompA NC_009801.1 1097662 1098714 R OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A complement(1097662..1098714) Escherichia coli E24377A 5589214 YP_001462190.1 CDS EcE24377A_1073 NC_009801.1 1098869 1099087 D identified by glimmer; hypothetical protein 1098869..1099087 Escherichia coli E24377A 5588382 YP_001462191.1 CDS sulA NC_009801.1 1099071 1099580 R identified by match to protein family HMM PF03846; match to protein family HMM TIGR00623; SOS cell division inhibitor complement(1099071..1099580) Escherichia coli E24377A 5586838 YP_001462192.1 CDS EcE24377A_1075 NC_009801.1 1099799 1100428 D identified by match to protein family HMM PF04993; match to protein family HMM PF04994; TfoX family protein 1099799..1100428 Escherichia coli E24377A 5589090 YP_001462193.1 CDS EcE24377A_1074 NC_009801.1 1100391 1102553 R identified by match to protein family HMM PF05976; match to protein family HMM TIGR01666; match to protein family HMM TIGR01667; hypothetical protein complement(1100391..1102553) Escherichia coli E24377A 5587174 YP_001462194.1 CDS EcE24377A_1076 NC_009801.1 1102563 1103009 R identified by match to protein family HMM PF03733; hypothetical protein complement(1102563..1103009) Escherichia coli E24377A 5589411 YP_001462195.1 CDS helD NC_009801.1 1103132 1105186 D catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1103132..1105186 Escherichia coli E24377A 5588374 YP_001462196.1 CDS mgsA NC_009801.1 1105218 1105676 R catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(1105218..1105676) Escherichia coli E24377A 5587017 YP_001462197.1 CDS EcE24377A_1079 NC_009801.1 1105772 1106434 R hypothetical protein complement(1105772..1106434) Escherichia coli E24377A 5589620 YP_001462198.1 CDS EcE24377A_1080 NC_009801.1 1106607 1107020 D identified by match to protein family HMM PF02629; CoA-binding protein 1106607..1107020 Escherichia coli E24377A 5587897 YP_001462199.1 CDS EcE24377A_1081 NC_009801.1 1107065 1107382 R identified by similarity to SP:P0AB20; match to protein family HMM PF08755; match to protein family HMM TIGR02097; heat shock protein HspQ complement(1107065..1107382) Escherichia coli E24377A 5586836 YP_001462200.1 CDS EcE24377A_1082 NC_009801.1 1107440 1108630 R identified by match to protein family HMM PF03602; hypothetical protein complement(1107440..1108630) Escherichia coli E24377A 5588681 YP_001462201.1 CDS tusE NC_009801.1 1109000 1109329 R transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE complement(1109000..1109329) Escherichia coli E24377A 5588095 YP_001462202.1 CDS EcE24377A_1084 NC_009801.1 1109420 1110079 R identified by match to protein family HMM PF01027; hypothetical protein complement(1109420..1110079) Escherichia coli E24377A 5587240 YP_001462203.1 CDS hyaA NC_009801.1 1110800 1111918 D identified by match to protein family HMM PF01058; match to protein family HMM PF08425; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409; nickel-dependent hydrogenase, small subunit 1110800..1111918 Escherichia coli E24377A 5590626 YP_001462204.1 CDS hyaB NC_009801.1 1111915 1113708 D involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1111915..1113708 Escherichia coli E24377A 5588780 YP_001462205.1 CDS hyaC NC_009801.1 1113727 1114434 D identified by match to protein family HMM PF01292; match to protein family HMM TIGR02125; hydrogenase 1 b-type cytochrome subunit 1113727..1114434 Escherichia coli E24377A 5588155 YP_001462206.1 CDS hyaD NC_009801.1 1114431 1115018 D HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1114431..1115018 Escherichia coli E24377A 5587860 YP_001462207.1 CDS hyaE NC_009801.1 1115015 1115413 D involved in processing hydrogenases HyaA and HyaB; hydrogenase-1 operon protein HyaE 1115015..1115413 Escherichia coli E24377A 5586062 YP_001462208.1 CDS hyaF NC_009801.1 1115410 1116267 D identified by similarity to SP:P19932; match to protein family HMM PF04809; hydrogenase-1 operon protein HyaF 1115410..1116267 Escherichia coli E24377A 5590018 YP_001462209.1 CDS appC NC_009801.1 1116401 1117945 D identified by match to protein family HMM PF01654; cytochrome bd-II oxidase subunit I 1116401..1117945 Escherichia coli E24377A 5588068 YP_001462210.1 CDS appB NC_009801.1 1117957 1119093 D identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203; cytochrome bd-II oxidase subunit II 1117957..1119093 Escherichia coli E24377A 5590706 YP_001462211.1 CDS EcE24377A_1095 NC_009801.1 1119106 1119198 D expressed during stationary phase; membrane protein 1119106..1119198 Escherichia coli E24377A 5588673 YP_001462212.1 CDS appA NC_009801.1 1119278 1120576 D identified by similarity to SP:P07102; match to protein family HMM PF00328; phosphoanhydride phosphorylase 1119278..1120576 Escherichia coli E24377A 5586193 YP_001462213.1 CDS etk NC_009801.1 1120691 1122871 R identified by similarity to SP:P38134; match to protein family HMM PF02706; cryptic autophosphorylating protein tyrosine kinase Etk complement(1120691..1122871) Escherichia coli E24377A 5589119 YP_001462214.1 CDS etp NC_009801.1 1122891 1123337 R Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk; phosphotyrosine-protein phosphatase complement(1122891..1123337) Escherichia coli E24377A 5589756 YP_001462215.1 CDS yccZ NC_009801.1 1123325 1124485 R identified by match to protein family HMM PF02563; outer membrane lipoprotein, group 4 capsule (G4C) polysaccharide complement(1123325..1124485) Escherichia coli E24377A 5589868 YP_001462216.1 CDS EcE24377A_1100 NC_009801.1 1124510 1126606 R identified by match to protein family HMM PF06082; lipoprotein complement(1124510..1126606) Escherichia coli E24377A 5590266 YP_001462217.1 CDS EcE24377A_1101 NC_009801.1 1126606 1127352 R identified by match to protein family HMM PF06251; hypothetical protein complement(1126606..1127352) Escherichia coli E24377A 5590053 YP_001462218.1 CDS ymcC NC_009801.1 1127349 1127993 R group 4 capsule (G4C) polysaccharide, lipoprotein YmcC complement(1127349..1127993) Escherichia coli E24377A 5586477 YP_001462219.1 CDS EcE24377A_1103 NC_009801.1 1128100 1128423 R identified by similarity to SP:P75885; inner membrane protein complement(1128100..1128423) Escherichia coli E24377A 5589326 YP_001462220.1 CDS EcE24377A_1104 NC_009801.1 1128847 1129059 R identified by match to protein family HMM PF00313; cold shock DNA-binding protein complement(1128847..1129059) Escherichia coli E24377A 5586906 YP_001462221.1 CDS EcE24377A_1105 NC_009801.1 1129345 1129557 D identified by match to protein family HMM PF00313; cold shock protein CspG 1129345..1129557 Escherichia coli E24377A 5588777 YP_001462222.1 CDS EcE24377A_1107 NC_009801.1 1129951 1130124 D identified by match to protein family HMM PF08178; GnsA/GnsB family transcriptional regulator 1129951..1130124 Escherichia coli E24377A 5589106 YP_001462223.1 CDS EcE24377A_1106 NC_009801.1 1129966 1130139 R identified by glimmer; hypothetical protein complement(1129966..1130139) Escherichia coli E24377A 5588633 YP_001462224.1 CDS EcE24377A_1108 NC_009801.1 1130172 1131245 R yccM; identified by match to protein family HMM PF00037; 4Fe-4S ferredoxin complement(1130172..1131245) Escherichia coli E24377A 5588867 YP_001462225.1 CDS EcE24377A_1109 NC_009801.1 1131119 1131283 R identified by glimmer; hypothetical protein complement(1131119..1131283) Escherichia coli E24377A 5586409 YP_001462226.1 CDS torS NC_009801.1 1131317 1134061 R Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS complement(1131317..1134061) Escherichia coli E24377A 5588660 YP_001462227.1 CDS torT NC_009801.1 1134144 1135172 D periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1134144..1135172 Escherichia coli E24377A 5586053 YP_001462228.1 CDS torR NC_009801.1 1135145 1135837 R response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR complement(1135145..1135837) Escherichia coli E24377A 5586934 YP_001462229.1 CDS torC NC_009801.1 1135967 1137139 D identified by similarity to SP:P33226; match to protein family HMM PF03264; match to protein family HMM TIGR02162; cytochrome c-type protein torC 1135967..1137139 Escherichia coli E24377A 5586657 YP_001462230.1 CDS torA NC_009801.1 1137139 1139685 D identified by similarity to SP:P33225; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409; match to protein family HMM TIGR02164; trimethylamine-N-oxide reductase 1137139..1139685 Escherichia coli E24377A 5588001 YP_001462231.1 CDS torD NC_009801.1 1139682 1140281 D TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1139682..1140281 Escherichia coli E24377A 5587048 YP_001462232.1 CDS EcE24377A_1115 NC_009801.1 1140221 1140370 R identified by glimmer; hypothetical protein complement(1140221..1140370) Escherichia coli E24377A 5590303 YP_001462233.1 CDS cbpM NC_009801.1 1140374 1140679 R with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM complement(1140374..1140679) Escherichia coli E24377A 5589569 YP_001462234.1 CDS cbpA NC_009801.1 1140679 1141599 R functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA complement(1140679..1141599) Escherichia coli E24377A 5586164 YP_001462235.1 CDS EcE24377A_1119 NC_009801.1 1141859 1143118 D identified by similarity to GB:AAP16515.1; hypothetical protein 1141859..1143118 Escherichia coli E24377A 5589296 YP_001462236.1 CDS agp NC_009801.1 1143409 1144650 D identified by similarity to SP:P19926; match to protein family HMM PF00328; glucose-1-phosphatase/inositol phosphatase 1143409..1144650 Escherichia coli E24377A 5589155 YP_001462237.1 CDS EcE24377A_1121 NC_009801.1 1144688 1144915 R hypothetical protein complement(1144688..1144915) Escherichia coli E24377A 5589815 YP_001462238.1 CDS wrbA NC_009801.1 1144936 1145532 R stationary phase that binds TrpR repressor; TrpR binding protein WrbA complement(1144936..1145532) Escherichia coli E24377A 5588061 YP_001462239.1 CDS EcE24377A_1123 NC_009801.1 1145905 1146078 D identified by similarity to GB:BAA35782.1; hypothetical protein 1145905..1146078 Escherichia coli E24377A 5587088 YP_001462240.1 CDS EcE24377A_1124 NC_009801.1 1146161 1147489 R identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; purine permease ycdG complement(1146161..1147489) Escherichia coli E24377A 5587228 YP_001462241.1 CDS EcE24377A_1125 NC_009801.1 1147510 1148004 R identified by similarity to SP:P75893; match to protein family HMM PF01613; flavin reductase rutF complement(1147510..1148004) Escherichia coli E24377A 5588270 YP_001462242.1 CDS EcE24377A_1126 NC_009801.1 1148015 1148605 R identified by similarity to SP:P75894; match to protein family HMM PF00881; hypothetical protein complement(1148015..1148605) Escherichia coli E24377A 5587315 YP_001462243.1 CDS EcE24377A_1127 NC_009801.1 1148615 1149415 R identified by similarity to SP:P75895; match to protein family HMM PF00561; rutD protein complement(1148615..1149415) Escherichia coli E24377A 5586931 YP_001462244.1 CDS EcE24377A_1128 NC_009801.1 1149423 1149809 R identified by similarity to SP:P0AFQ5; match to protein family HMM PF01042; rutC protein complement(1149423..1149809) Escherichia coli E24377A 5587950 YP_001462245.1 CDS EcE24377A_1129 NC_009801.1 1149821 1150516 R identified by similarity to SP:P75897; match to protein family HMM PF00857; isochorismatase, rutB complement(1149821..1150516) Escherichia coli E24377A 5589697 YP_001462246.1 CDS EcE24377A_1130 NC_009801.1 1150513 1151694 R identified by similarity to SP:P75898; match to protein family HMM PF00296; monooxygenase rutA complement(1150513..1151694) Escherichia coli E24377A 5589956 YP_001462247.1 CDS rutR NC_009801.1 1151891 1152529 D identified by similarity to SP:P0ACU2; match to protein family HMM PF00440; match to protein family HMM PF08362; transcriptional regulator RutR 1151891..1152529 Escherichia coli E24377A 5588865 YP_001462248.1 CDS putA NC_009801.1 1152569 1156531 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(1152569..1156531) Escherichia coli E24377A 5585999 YP_001462249.1 CDS EcE24377A_1134 NC_009801.1 1156586 1156795 D hypothetical protein 1156586..1156795 Escherichia coli E24377A 5586666 YP_001462250.1 CDS putP NC_009801.1 1156954 1158462 D identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121; sodium/proline symporter 1156954..1158462 Escherichia coli E24377A 5589726 YP_001462251.1 CDS EcE24377A_1136 NC_009801.1 1159004 1159834 D identified by match to protein family HMM PF03239; match to protein family HMM TIGR00145; FTR1 family iron permease 1159004..1159834 Escherichia coli E24377A 5586702 YP_001462252.1 CDS EcE24377A_1137 NC_009801.1 1159892 1161019 D identified by match to protein family HMM PF04302; hypothetical protein 1159892..1161019 Escherichia coli E24377A 5588498 YP_001462253.1 CDS EcE24377A_1138 NC_009801.1 1161025 1162296 D identified by match to protein family HMM PF04261; match to protein family HMM TIGR01409; match to protein family HMM TIGR01412; match to protein family HMM TIGR01413; Tat-translocated enzyme 1161025..1162296 Escherichia coli E24377A 5589030 YP_001462254.1 CDS EcE24377A_1139 NC_009801.1 1162363 1162560 R identified by glimmer; hypothetical protein complement(1162363..1162560) Escherichia coli E24377A 5588737 YP_001462255.1 CDS pgaD NC_009801.1 1163753 1164166 R in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; PGA biosynthesis protein complement(1163753..1164166) Escherichia coli E24377A 5588317 YP_001462256.1 CDS pgaC NC_009801.1 1164168 1165493 R predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase complement(1164168..1165493) Escherichia coli E24377A 5589816 YP_001462257.1 CDS pgaB NC_009801.1 1165486 1167504 R in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase complement(1165486..1167504) Escherichia coli E24377A 5587951 YP_001462258.1 CDS pgaA NC_009801.1 1167513 1169936 R outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA complement(1167513..1169936) Escherichia coli E24377A 5588807 YP_001462259.1 CDS EcE24377A_1145 NC_009801.1 1170451 1171881 D identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 1170451..1171881 Escherichia coli E24377A 5588047 YP_001462260.1 CDS EcE24377A_1146 NC_009801.1 1171922 1172788 R identified by similarity to SP:P05822; match to protein family HMM PF00665; IS3, transposase orfB complement(1171922..1172788) Escherichia coli E24377A 5589503 YP_001462261.1 CDS EcE24377A_1147 NC_009801.1 1172785 1173084 R identified by match to protein family HMM PF01527; IS3, transposase orfA complement(1172785..1173084) Escherichia coli E24377A 5590062 YP_001462262.1 CDS EcE24377A_1148 NC_009801.1 1173134 1173499 D identified by glimmer; hypothetical protein 1173134..1173499 Escherichia coli E24377A 5585947 YP_001462263.1 CDS EcE24377A_1149 NC_009801.1 1173489 1174475 D hypothetical protein 1173489..1174475 Escherichia coli E24377A 5590322 YP_001462264.1 CDS EcE24377A_1151 NC_009801.1 1175217 1175330 R identified by glimmer; hypothetical protein complement(1175217..1175330) Escherichia coli E24377A 5590802 YP_001462265.1 CDS EcE24377A_1153 NC_009801.1 1176344 1177081 D identified by match to protein family HMM PF02811; hydrolase 1176344..1177081 Escherichia coli E24377A 5588410 YP_001462266.1 CDS EcE24377A_1154 NC_009801.1 1177105 1177659 D identified by match to protein family HMM PF06192; chaperone TorD 1177105..1177659 Escherichia coli E24377A 5588932 YP_001462267.1 CDS EcE24377A_1155 NC_009801.1 1177761 1178252 D identified by match to protein family HMM PF06496; hypothetical protein 1177761..1178252 Escherichia coli E24377A 5589678 YP_001462268.1 CDS csgG NC_009801.1 1178316 1179149 R identified by match to protein family HMM PF03783; curli production assembly/transport subunit CsgG complement(1178316..1179149) Escherichia coli E24377A 5589575 YP_001462269.1 CDS csgF NC_009801.1 1179176 1179592 R nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF complement(1179176..1179592) Escherichia coli E24377A 5587494 YP_001462270.1 CDS csgE NC_009801.1 1179617 1180006 R chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE complement(1179617..1180006) Escherichia coli E24377A 5590765 YP_001462271.1 CDS csgD NC_009801.1 1180011 1180661 R activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD complement(1180011..1180661) Escherichia coli E24377A 5590727 YP_001462272.1 CDS EcE24377A_1160 NC_009801.1 1181073 1181321 R identified by glimmer; hypothetical protein complement(1181073..1181321) Escherichia coli E24377A 5588920 YP_001462273.1 CDS csgB NC_009801.1 1181388 1181870 D CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1181388..1181870 Escherichia coli E24377A 5589677 YP_001462274.1 CDS EcE24377A_1162 NC_009801.1 1181911 1182366 D identified by similarity to SP:P28307; match to protein family HMM PF07012; cryptic curlin major subunit 1181911..1182366 Escherichia coli E24377A 5588778 YP_001462275.1 CDS csgC NC_009801.1 1182425 1182757 D involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1182425..1182757 Escherichia coli E24377A 5587878 YP_001462276.1 CDS EcE24377A_1164 NC_009801.1 1182878 1183189 D hypothetical protein 1182878..1183189 Escherichia coli E24377A 5587511 YP_001462277.1 CDS EcE24377A_1165 NC_009801.1 1183284 1183817 D identified by match to protein family HMM PF01661; hypothetical protein 1183284..1183817 Escherichia coli E24377A 5589746 YP_001462278.1 CDS EcE24377A_1166 NC_009801.1 1183810 1185240 D identified by match to protein family HMM PF00614; phopholipase D 1183810..1185240 Escherichia coli E24377A 5589506 YP_001462279.1 CDS mdoC NC_009801.1 1185248 1186405 R required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein complement(1185248..1186405) Escherichia coli E24377A 5586057 YP_001462280.1 CDS EcE24377A_1168 NC_009801.1 1186450 1186593 R identified by glimmer; hypothetical protein complement(1186450..1186593) Escherichia coli E24377A 5589081 YP_001462281.1 CDS mdoG NC_009801.1 1186799 1188334 D involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1186799..1188334 Escherichia coli E24377A 5590258 YP_001462282.1 CDS mdoH NC_009801.1 1188327 1190870 D necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1188327..1190870 Escherichia coli E24377A 5589701 YP_001462283.1 CDS EcE24377A_1172 NC_009801.1 1191043 1191270 D identified by match to protein family HMM PF07119; hypothetical protein 1191043..1191270 Escherichia coli E24377A 5587296 YP_001462284.1 CDS msyB NC_009801.1 1191271 1191645 R hypothetical protein complement(1191271..1191645) Escherichia coli E24377A 5589418 YP_001462285.1 CDS mdtG NC_009801.1 1191728 1192954 R Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG complement(1191728..1192954) Escherichia coli E24377A 5588013 YP_001462286.1 CDS EcE24377A_1175 NC_009801.1 1192984 1193088 D identified by glimmer; hypothetical protein 1192984..1193088 Escherichia coli E24377A 5589427 YP_001462287.1 CDS htrB NC_009801.1 1193126 1194046 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1193126..1194046) Escherichia coli E24377A 5589925 YP_001462288.1 CDS EcE24377A_1177 NC_009801.1 1194271 1195323 D identified by match to protein family HMM PF00581; hypothetical protein 1194271..1195323 Escherichia coli E24377A 5590866 YP_001462289.1 CDS yceI NC_009801.1 1195365 1195940 R identified by match to protein family HMM PF04264; hypothetical protein complement(1195365..1195940) Escherichia coli E24377A 5589370 YP_001462290.1 CDS EcE24377A_1179 NC_009801.1 1195944 1196510 R identified by match to protein family HMM PF01292; nickel-dependent hydrogenase b-type cytochrome subunit complement(1195944..1196510) Escherichia coli E24377A 5587837 YP_001462291.1 CDS EcE24377A_1180 NC_009801.1 1196500 1196646 D hypothetical protein 1196500..1196646 Escherichia coli E24377A 5590128 YP_001462292.1 CDS EcE24377A_1181 NC_009801.1 1196771 1196884 R identified by similarity to RF:NP_460130.1; hypothetical protein complement(1196771..1196884) Escherichia coli E24377A 5590457 YP_001462293.1 CDS solA NC_009801.1 1196932 1198050 R catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase complement(1196932..1198050) Escherichia coli E24377A 5588901 YP_001462294.1 CDS bssS NC_009801.1 1198165 1198422 R BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS complement(1198165..1198422) Escherichia coli E24377A 5587441 YP_001462295.1 CDS dinI NC_009801.1 1198709 1198954 R identified by similarity to SP:P0ABR4; match to protein family HMM PF06183; DNA damage-inducible protein I complement(1198709..1198954) Escherichia coli E24377A 5590237 YP_001462296.1 CDS pyrC NC_009801.1 1199028 1200074 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1199028..1200074) Escherichia coli E24377A 5586994 YP_001462297.1 CDS EcE24377A_1186 NC_009801.1 1200180 1200740 R identified by match to protein family HMM PF07273; hypothetical protein complement(1200180..1200740) Escherichia coli E24377A 5588299 YP_001462298.1 CDS grxB NC_009801.1 1200874 1201521 R cofactor involved in the reduction of disulfides; glutaredoxin complement(1200874..1201521) Escherichia coli E24377A 5589478 YP_001462299.1 CDS mdtH NC_009801.1 1201585 1202793 R Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH complement(1201585..1202793) Escherichia coli E24377A 5586168 YP_001462300.1 CDS rimJ NC_009801.1 1203029 1203613 D identified by similarity to SP:P0A948; match to protein family HMM PF00583; ribosomal-protein-S5-alanine N-acetyltransferase 1203029..1203613 Escherichia coli E24377A 5587278 YP_001462301.1 CDS EcE24377A_1190 NC_009801.1 1203624 1204271 D identified by match to protein family HMM PF04337; hypothetical protein 1203624..1204271 Escherichia coli E24377A 5586121 YP_001462302.1 CDS EcE24377A_1191 NC_009801.1 1204273 1205196 D identified by match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase 1204273..1205196 Escherichia coli E24377A 5588630 YP_001462303.1 CDS mviN NC_009801.1 1205306 1206841 D identified by match to protein family HMM PF03023; match to protein family HMM TIGR01695; integral membrane protein MviN 1205306..1206841 Escherichia coli E24377A 5589498 YP_001462304.1 CDS flgN NC_009801.1 1206881 1207297 R identified by match to protein family HMM PF05130; flagellar synthesis protein FlgN complement(1206881..1207297) Escherichia coli E24377A 5590355 YP_001462305.1 CDS flgM NC_009801.1 1207302 1207595 R regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM complement(1207302..1207595) Escherichia coli E24377A 5590469 YP_001462306.1 CDS flgA NC_009801.1 1207671 1208330 R required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1207671..1208330) Escherichia coli E24377A 5588893 YP_001462307.1 CDS flgB NC_009801.1 1208485 1208901 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal-body rod protein FlgB 1208485..1208901 Escherichia coli E24377A 5590087 YP_001462308.1 CDS flgC NC_009801.1 1208905 1209309 D with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1208905..1209309 Escherichia coli E24377A 5588717 YP_001462309.1 CDS flgD NC_009801.1 1209321 1210016 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1209321..1210016 Escherichia coli E24377A 5587507 YP_001462310.1 CDS flgE NC_009801.1 1210041 1211246 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1210041..1211246 Escherichia coli E24377A 5590183 YP_001462311.1 CDS flgF NC_009801.1 1211266 1212021 D FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1211266..1212021 Escherichia coli E24377A 5589625 YP_001462312.1 CDS flgG NC_009801.1 1212159 1212941 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1212159..1212941 Escherichia coli E24377A 5589807 YP_001462313.1 CDS flgH NC_009801.1 1212994 1213692 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1212994..1213692 Escherichia coli E24377A 5587566 YP_001462314.1 CDS flgI NC_009801.1 1213704 1214801 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 1213704..1214801 Escherichia coli E24377A 5588018 YP_001462315.1 CDS flgJ NC_009801.1 1214801 1215742 D Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1214801..1215742 Escherichia coli E24377A 5586381 YP_001462316.1 CDS flgK NC_009801.1 1215808 1217451 D with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1215808..1217451 Escherichia coli E24377A 5590294 YP_001462317.1 CDS flgL NC_009801.1 1217463 1218416 D with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1217463..1218416 Escherichia coli E24377A 5590180 YP_001462318.1 CDS rne NC_009801.1 1218613 1221798 R bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E complement(1218613..1221798) Escherichia coli E24377A 5587728 YP_001462319.1 CDS rluC NC_009801.1 1222371 1223330 D catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1222371..1223330 Escherichia coli E24377A 5589539 YP_001462320.1 CDS maf2 NC_009801.1 1223442 1224065 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(1223442..1224065) Escherichia coli E24377A 5588658 YP_001462321.1 CDS EcE24377A_1210 NC_009801.1 1224225 1224746 D identified by match to protein family HMM PF02620; hypothetical protein 1224225..1224746 Escherichia coli E24377A 5588489 YP_001462322.1 CDS plsX NC_009801.1 1225052 1226122 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1225052..1226122 Escherichia coli E24377A 5590026 YP_001462323.1 CDS fabH NC_009801.1 1226190 1227143 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1226190..1227143 Escherichia coli E24377A 5586313 YP_001462324.1 CDS fabD NC_009801.1 1227159 1228088 D identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128; malonyl CoA-acyl carrier protein transacylase 1227159..1228088 Escherichia coli E24377A 5589212 YP_001462325.1 CDS fabG NC_009801.1 1228101 1228835 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1228101..1228835 Escherichia coli E24377A 5590805 YP_001462326.1 CDS acpP NC_009801.1 1229046 1229282 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1229046..1229282 Escherichia coli E24377A 5588521 YP_001462327.1 CDS fabF NC_009801.1 1229370 1230611 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1229370..1230611 Escherichia coli E24377A 5587541 YP_001462328.1 CDS pabC NC_009801.1 1230731 1231540 D catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1230731..1231540 Escherichia coli E24377A 5590011 YP_001462329.1 CDS EcE24377A_1218 NC_009801.1 1231543 1232565 D identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247; hypothetical protein 1231543..1232565 Escherichia coli E24377A 5590738 YP_001462330.1 CDS tmk NC_009801.1 1232555 1233196 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1232555..1233196 Escherichia coli E24377A 5589938 YP_001462331.1 CDS holB NC_009801.1 1233193 1234197 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1233193..1234197 Escherichia coli E24377A 5586615 YP_001462332.1 CDS EcE24377A_1221 NC_009801.1 1234208 1235005 D identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; metallodependent hydrolase 1234208..1235005 Escherichia coli E24377A 5589878 YP_001462333.1 CDS ptsG NC_009801.1 1235300 1236733 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC 1235300..1236733 Escherichia coli E24377A 5589194 YP_001462334.1 CDS fhuE NC_009801.1 1236793 1238982 R identified by similarity to SP:P16869; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783; ferric-rhodotorulic acid outer membrane transporter complement(1236793..1238982) Escherichia coli E24377A 5588326 YP_001462335.1 CDS EcE24377A_1224 NC_009801.1 1239015 1239185 R hypothetical protein complement(1239015..1239185) Escherichia coli E24377A 5590528 YP_001462336.1 CDS hinT NC_009801.1 1239316 1239675 D identified by similarity to SP:P0ACE7; match to protein family HMM PF01230; purine nucleoside phosphoramidase 1239316..1239675 Escherichia coli E24377A 5587061 YP_001462337.1 CDS EcE24377A_1226 NC_009801.1 1239678 1240055 D identified by match to protein family HMM PF07233; lipoprotein 1239678..1240055 Escherichia coli E24377A 5590324 YP_001462338.1 CDS EcE24377A_1227 NC_009801.1 1240069 1240710 D identified by match to protein family HMM TIGR02722; lipoprotein 1240069..1240710 Escherichia coli E24377A 5589067 YP_001462339.1 CDS thiK NC_009801.1 1240691 1241515 D catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1240691..1241515 Escherichia coli E24377A 5589021 YP_001462340.1 CDS nagZ NC_009801.1 1241526 1242551 D hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1241526..1242551 Escherichia coli E24377A 5590708 YP_001462341.1 CDS EcE24377A_1230 NC_009801.1 1242574 1243116 D identified by match to protein family HMM PF05728; hypothetical protein 1242574..1243116 Escherichia coli E24377A 5590185 YP_001462342.1 CDS ndh NC_009801.1 1243524 1244828 D identified by similarity to SP:P00393; match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF07992; NADH dehydrogenase 1243524..1244828 Escherichia coli E24377A 5590426 YP_001462343.1 CDS EcE24377A_1232 NC_009801.1 1245055 1245594 D identified by match to protein family HMM PF05433; hypothetical protein 1245055..1245594 Escherichia coli E24377A 5588547 YP_001462344.1 CDS EcE24377A_1233 NC_009801.1 1245656 1246366 R identified by match to protein family HMM PF00440; TetR family transcriptional regulator complement(1245656..1246366) Escherichia coli E24377A 5590402 YP_001462345.1 CDS EcE24377A_1234 NC_009801.1 1246529 1246786 D identified by match to protein family HMM PF07338; hypothetical protein 1246529..1246786 Escherichia coli E24377A 5586681 YP_001462346.1 CDS EcE24377A_1235 NC_009801.1 1246869 1247831 R identified by match to protein family HMM PF01476; match to protein family HMM PF03734; LysM/ErfK/YbiS/YcfS/YnhG family protein complement(1246869..1247831) Escherichia coli E24377A 5590513 YP_001462347.1 CDS mfd NC_009801.1 1247975 1251421 R identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580; transcription-repair coupling factor complement(1247975..1251421) Escherichia coli E24377A 5590455 YP_001462348.1 CDS EcE24377A_1237 NC_009801.1 1251549 1252622 R identified by match to protein family HMM PF01757; hypothetical protein complement(1251549..1252622) Escherichia coli E24377A 5589207 YP_001462349.1 CDS lolC NC_009801.1 1252884 1254083 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1252884..1254083 Escherichia coli E24377A 5590529 YP_001462350.1 CDS lolD NC_009801.1 1254076 1254777 D outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1254076..1254777 Escherichia coli E24377A 5587325 YP_001462351.1 CDS lolE NC_009801.1 1254777 1256021 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1254777..1256021 Escherichia coli E24377A 5586071 YP_001462352.1 CDS nagK NC_009801.1 1256050 1256961 D catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1256050..1256961 Escherichia coli E24377A 5588823 YP_001462353.1 CDS EcE24377A_1243 NC_009801.1 1257937 1258725 R hypothetical protein complement(1257937..1258725) Escherichia coli E24377A 5590632 YP_001462354.1 CDS EcE24377A_1244 NC_009801.1 1258722 1259183 R hypothetical protein complement(1258722..1259183) Escherichia coli E24377A 5589182 YP_001462355.1 CDS EcE24377A_1245 NC_009801.1 1259025 1259162 D identified by glimmer; hypothetical protein 1259025..1259162 Escherichia coli E24377A 5586948 YP_001462356.1 CDS potD NC_009801.1 1259241 1260287 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein complement(1259241..1260287) Escherichia coli E24377A 5590423 YP_001462357.1 CDS potC NC_009801.1 1260284 1261078 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1260284..1261078) Escherichia coli E24377A 5588762 YP_001462358.1 CDS EcE24377A_1248 NC_009801.1 1262112 1263230 R identified by match to protein family HMM PF00589; match to protein family HMM PF09003; phage integrase complement(1262112..1263230) Escherichia coli E24377A 5590340 YP_001462359.1 CDS EcE24377A_1249 NC_009801.1 1263199 1263468 R identified by similarity to SP:P27079; excisionase complement(1263199..1263468) Escherichia coli E24377A 5586258 YP_001462360.1 CDS EcE24377A_1250 NC_009801.1 1263530 1264297 R exonuclease complement(1263530..1264297) Escherichia coli E24377A 5590052 YP_001462361.1 CDS EcE24377A_1251 NC_009801.1 1264375 1265907 R exonuclease complement(1264375..1265907) Escherichia coli E24377A 5586341 YP_001462362.1 CDS EcE24377A_1252 NC_009801.1 1266001 1266192 R identified by similarity to GB:AAN79873.1; match to protein family HMM PF07358; hypothetical protein complement(1266001..1266192) Escherichia coli E24377A 5587455 YP_001462363.1 CDS EcE24377A_1253 NC_009801.1 1266189 1266482 R identified by match to protein family HMM PF05358; DicB protein complement(1266189..1266482) Escherichia coli E24377A 5588049 YP_001462364.1 CDS EcE24377A_1254 NC_009801.1 1266941 1267150 D identified by glimmer; hypothetical protein 1266941..1267150 Escherichia coli E24377A 5589298 YP_001462365.1 CDS EcE24377A_1255 NC_009801.1 1267151 1267789 R identified by glimmer; hypothetical protein complement(1267151..1267789) Escherichia coli E24377A 5590743 YP_001462366.1 CDS EcE24377A_1256 NC_009801.1 1267801 1268034 R identified by match to protein family HMM PF07151; hypothetical protein complement(1267801..1268034) Escherichia coli E24377A 5587659 YP_001462367.1 CDS EcE24377A_1257 NC_009801.1 1268525 1268716 R identified by similarity to GB:AAK16987.1; hypothetical protein complement(1268525..1268716) Escherichia coli E24377A 5590385 YP_001462368.1 CDS EcE24377A_1258 NC_009801.1 1269506 1269931 D identified by similarity to GB:AAN79880.1; match to protein family HMM PF06254; hypothetical protein 1269506..1269931 Escherichia coli E24377A 5586021 YP_001462369.1 CDS EcE24377A_1259 NC_009801.1 1269955 1270902 D identified by similarity to SP:P03688; phage O family protein 1269955..1270902 Escherichia coli E24377A 5588638 YP_001462370.1 CDS EcE24377A_1260 NC_009801.1 1270909 1271655 D identified by similarity to SP:P0AEF0; match to protein family HMM PF01695; replication protein 1270909..1271655 Escherichia coli E24377A 5586250 YP_001462371.1 CDS EcE24377A_1261 NC_009801.1 1271677 1272438 D identified by similarity to GB:AAG56436.1; match to protein family HMM PF07789; hypothetical protein 1271677..1272438 Escherichia coli E24377A 5590834 YP_001462372.1 CDS EcE24377A_1262 NC_009801.1 1272454 1272876 D identified by match to protein family HMM PF06163; hypothetical protein 1272454..1272876 Escherichia coli E24377A 5588178 YP_001462373.1 CDS EcE24377A_1263 NC_009801.1 1272879 1273223 D identified by similarity to GB:BAB34936.1; hypothetical protein 1272879..1273223 Escherichia coli E24377A 5590027 YP_001462374.1 CDS EcE24377A_1264 NC_009801.1 1273326 1273430 R identified by glimmer; hypothetical protein complement(1273326..1273430) Escherichia coli E24377A 5586872 YP_001462375.1 CDS EcE24377A_1265 NC_009801.1 1273395 1273817 D hypothetical protein 1273395..1273817 Escherichia coli E24377A 5586421 YP_001462376.1 CDS EcE24377A_1266 NC_009801.1 1274711 1275766 D identified by similarity to GB:AAZ88571.1; match to protein family HMM PF06914; hypothetical protein 1274711..1275766 Escherichia coli E24377A 5589991 YP_001462377.1 CDS EcE24377A_1267 NC_009801.1 1275767 1276132 D identified by similarity to SP:Q9MCN8; match to protein family HMM PF05866; crossover junction endodeoxyribonuclease RusA-like protein 1275767..1276132 Escherichia coli E24377A 5586592 YP_001462378.1 CDS EcE24377A_1268 NC_009801.1 1276129 1276818 D identified by match to protein family HMM PF06323; phage antitermination protein Q 1276129..1276818 Escherichia coli E24377A 5585897 YP_001462379.1 CDS EcE24377A_1269 NC_009801.1 1276963 1277727 D identified by match to protein family HMM PF00069; protein kinase domain-containing protein 1276963..1277727 Escherichia coli E24377A 5586532 YP_001462380.1 CDS EcE24377A_1270 NC_009801.1 1277724 1278467 D identified by glimmer; hypothetical protein 1277724..1278467 Escherichia coli E24377A 5585983 YP_001462381.1 CDS EcE24377A_1271 NC_009801.1 1278600 1278884 D hypothetical protein 1278600..1278884 Escherichia coli E24377A 5588098 YP_001462382.1 CDS EcE24377A_1272 NC_009801.1 1279035 1280084 D identified by match to protein family HMM PF01555; DNA methylase 1279035..1280084 Escherichia coli E24377A 5586446 YP_001462383.1 CDS EcE24377A_1276 NC_009801.1 1280912 1281304 D identified by similarity to GB:CAC83546.1; hypothetical protein 1280912..1281304 Escherichia coli E24377A 5590321 YP_001462384.1 CDS EcE24377A_1277 NC_009801.1 1281294 1281569 D identified by similarity to GB:AAO06087.1; match to protein family HMM PF05449; phage holin 1281294..1281569 Escherichia coli E24377A 5589099 YP_001462385.1 CDS EcE24377A_1278 NC_009801.1 1281572 1281949 D hypothetical protein 1281572..1281949 Escherichia coli E24377A 5590608 YP_001462386.1 CDS EcE24377A_1279 NC_009801.1 1281957 1282061 D identified by glimmer; hypothetical protein 1281957..1282061 Escherichia coli E24377A 5590386 YP_001462387.1 CDS EcE24377A_1280 NC_009801.1 1283046 1283210 D lipoprotein 1283046..1283210 Escherichia coli E24377A 5588783 YP_001462388.1 CDS EcE24377A_1281 NC_009801.1 1283292 1283846 D identified by match to protein family HMM PF07471; phage DNA packaging protein Nu1 1283292..1283846 Escherichia coli E24377A 5590277 YP_001462389.1 CDS EcE24377A_1282 NC_009801.1 1283798 1284043 D identified by match to protein family HMM PF06316; match to protein family HMM TIGR03304; entero Ail/Lom protein 1283798..1284043 Escherichia coli E24377A 5586119 YP_001462390.1 CDS EcE24377A_1284 NC_009801.1 1284108 1287521 D identified by match to protein family HMM PF03335; match to protein family HMM PF03406; match to protein family HMM PF07484; match to protein family HMM PF08400; phage tail domain-containing protein 1284108..1287521 Escherichia coli E24377A 5588402 YP_001462391.1 CDS EcE24377A_1285 NC_009801.1 1287521 1288105 D identified by similarity to SP:P03740; match to protein family HMM PF02413; tail fiber assembly protein 1287521..1288105 Escherichia coli E24377A 5589065 YP_001462392.1 CDS EcE24377A_1286 NC_009801.1 1288160 1288816 R identified by match to protein family HMM PF08241; match to protein family HMM PF08242; hypothetical protein complement(1288160..1288816) Escherichia coli E24377A 5587959 YP_001462393.1 CDS EcE24377A_1287 NC_009801.1 1288885 1289151 D identified by glimmer; hypothetical protein 1288885..1289151 Escherichia coli E24377A 5590792 YP_001462394.1 CDS potB NC_009801.1 1289384 1290247 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1289384..1290247) Escherichia coli E24377A 5588738 YP_001462395.1 CDS potA NC_009801.1 1290231 1291367 R functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase complement(1290231..1291367) Escherichia coli E24377A 5589414 YP_001462396.1 CDS pepT NC_009801.1 1291617 1292846 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1291617..1292846 Escherichia coli E24377A 5586690 YP_001462397.1 CDS EcE24377A_1291 NC_009801.1 1292992 1294113 R identified by match to protein family HMM PF08007; cupin family protein complement(1292992..1294113) Escherichia coli E24377A 5589440 YP_001462398.1 CDS phoQ NC_009801.1 1294189 1295649 R identified by similarity to SP:P23837; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF08918; sensor protein PhoQ complement(1294189..1295649) Escherichia coli E24377A 5588755 YP_001462399.1 CDS phoP NC_009801.1 1295649 1296320 R response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP complement(1295649..1296320) Escherichia coli E24377A 5589859 YP_001462400.1 CDS purB NC_009801.1 1296488 1297858 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(1296488..1297858) Escherichia coli E24377A 5588089 YP_001462401.1 CDS EcE24377A_1295 NC_009801.1 1297862 1298503 R HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein complement(1297862..1298503) Escherichia coli E24377A 5585956 YP_001462402.1 CDS mnmA NC_009801.1 1298539 1299645 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1298539..1299645) Escherichia coli E24377A 5588042 YP_001462403.1 CDS EcE24377A_1297 NC_009801.1 1299699 1300160 R identified by match to protein family HMM PF00293; NUDIX family hydrolase complement(1299699..1300160) Escherichia coli E24377A 5590863 YP_001462404.1 CDS rluE NC_009801.1 1300170 1300823 R catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E complement(1300170..1300823) Escherichia coli E24377A 5588029 YP_001462405.1 CDS icd NC_009801.1 1300995 1302245 D Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1300995..1302245 Escherichia coli E24377A 5586891 YP_001462406.1 CDS EcE24377A_1300 NC_009801.1 1303367 1303771 R identified by match to protein family HMM PF07166; hypothetical protein complement(1303367..1303771) Escherichia coli E24377A 5589696 YP_001462407.1 CDS EcE24377A_1301 NC_009801.1 1303992 1304723 R identified by similarity to SP:P33358; match to protein family HMM PF00376; transcriptional regulator mlrA-like protein complement(1303992..1304723) Escherichia coli E24377A 5590150 YP_001462408.1 CDS EcE24377A_1302 NC_009801.1 1304633 1304785 R identified by glimmer; hypothetical protein complement(1304633..1304785) Escherichia coli E24377A 5587736 YP_001462409.1 CDS EcE24377A_1303 NC_009801.1 1304928 1306139 R identified by match to protein family HMM PF00563; match to protein family HMM PF04940; BLUF/cyclic diguanylate phosphodiesterase domain-containing protein complement(1304928..1306139) Escherichia coli E24377A 5590123 YP_001462410.1 CDS EcE24377A_1304 NC_009801.1 1306732 1307004 D identified by similarity to SP:P75992; hypothetical protein 1306732..1307004 Escherichia coli E24377A 5586362 YP_001462411.1 CDS EcE24377A_1305 NC_009801.1 1307033 1307299 D hypothetical protein 1307033..1307299 Escherichia coli E24377A 5587007 YP_001462412.1 CDS EcE24377A_1306 NC_009801.1 1307412 1307660 D hypothetical protein 1307412..1307660 Escherichia coli E24377A 5589761 YP_001462413.1 CDS EcE24377A_1307 NC_009801.1 1307950 1309515 D identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase domain-containing protein 1307950..1309515 Escherichia coli E24377A 5588131 YP_001462414.1 CDS EcE24377A_1308 NC_009801.1 1309647 1309865 D ymgF; hypothetical protein 1309647..1309865 Escherichia coli E24377A 5590369 YP_001462415.1 CDS EcE24377A_1309 NC_009801.1 1309958 1310101 D identified by glimmer; hypothetical protein 1309958..1310101 Escherichia coli E24377A 5586296 YP_001462416.1 CDS EcE24377A_1310 NC_009801.1 1310265 1310474 D identified by glimmer; hypothetical protein 1310265..1310474 Escherichia coli E24377A 5590019 YP_001462417.1 CDS EcE24377A_1311 NC_009801.1 1310730 1310870 D identified by glimmer; hypothetical protein 1310730..1310870 Escherichia coli E24377A 5586163 YP_001462418.1 CDS EcE24377A_1312 NC_009801.1 1311992 1312912 D identified by match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR03304; autotransporter (AT) family porin 1311992..1312912 Escherichia coli E24377A 5588165 YP_001462419.1 CDS EcE24377A_1313 NC_009801.1 1312969 1313298 R ymgD; identified by glimmer; hypothetical protein complement(1312969..1313298) Escherichia coli E24377A 5590446 YP_001462420.1 CDS EcE24377A_1314 NC_009801.1 1313308 1313652 R identified by similarity to GB:ABB13223.1; hypothetical protein complement(1313308..1313652) Escherichia coli E24377A 5587373 YP_001462421.1 CDS EcE24377A_1315 NC_009801.1 1313654 1313827 R identified by glimmer; hypothetical protein complement(1313654..1313827) Escherichia coli E24377A 5587414 YP_001462422.1 CDS EcE24377A_1316 NC_009801.1 1314074 1314193 D identified by glimmer; hypothetical protein 1314074..1314193 Escherichia coli E24377A 5590156 YP_001462423.1 CDS EcE24377A_1317 NC_009801.1 1314162 1314572 D identified by glimmer; hypothetical protein 1314162..1314572 Escherichia coli E24377A 5588700 YP_001462424.1 CDS minE NC_009801.1 1314944 1315210 R works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE complement(1314944..1315210) Escherichia coli E24377A 5588623 YP_001462425.1 CDS minD NC_009801.1 1315214 1316026 R ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD complement(1315214..1316026) Escherichia coli E24377A 5589493 YP_001462426.1 CDS minC NC_009801.1 1316050 1316745 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(1316050..1316745) Escherichia coli E24377A 5589377 YP_001462427.1 CDS EcE24377A_1321 NC_009801.1 1317265 1317633 D identified by match to protein family HMM PF05666; fels-1 prophage protein 1317265..1317633 Escherichia coli E24377A 5587207 YP_001462428.1 CDS EcE24377A_1322 NC_009801.1 1317753 1318154 R identified by match to protein family HMM PF04151; pre-peptidase C-terminal domain-containing protein complement(1317753..1318154) Escherichia coli E24377A 5589714 YP_001462429.1 CDS EcE24377A_1323 NC_009801.1 1318396 1318689 D identified by match to protein family HMM PF05166; hypothetical protein 1318396..1318689 Escherichia coli E24377A 5587344 YP_001462430.1 CDS EcE24377A_1324 NC_009801.1 1318761 1319420 D identified by match to protein family HMM PF01557; hypothetical protein 1318761..1319420 Escherichia coli E24377A 5587592 YP_001462431.1 CDS EcE24377A_1325 NC_009801.1 1319497 1319958 D identified by match to protein family HMM PF03692; hypothetical protein 1319497..1319958 Escherichia coli E24377A 5586591 YP_001462432.1 CDS EcE24377A_1327 NC_009801.1 1321212 1321322 R identified by glimmer; hypothetical protein complement(1321212..1321322) Escherichia coli E24377A 5588214 YP_001462433.1 CDS umuD NC_009801.1 1321448 1321867 D binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1321448..1321867 Escherichia coli E24377A 5586979 YP_001462434.1 CDS umuC NC_009801.1 1321867 1323135 D binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1321867..1323135 Escherichia coli E24377A 5590061 YP_001462435.1 CDS dsbB NC_009801.1 1323181 1323711 R disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B complement(1323181..1323711) Escherichia coli E24377A 5590117 YP_001462436.1 CDS nhaB NC_009801.1 1323857 1325398 R involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter complement(1323857..1325398) Escherichia coli E24377A 5587572 YP_001462437.1 CDS fadR NC_009801.1 1325620 1326339 D Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1325620..1326339 Escherichia coli E24377A 5587451 YP_001462438.1 CDS EcE24377A_1333 NC_009801.1 1326391 1327923 R identified by match to protein family HMM PF04293; SpoVR family protein complement(1326391..1327923) Escherichia coli E24377A 5588943 YP_001462439.1 CDS dadA NC_009801.1 1328253 1329551 D catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1328253..1329551 Escherichia coli E24377A 5587987 YP_001462440.1 CDS dadX NC_009801.1 1329561 1330631 D catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1329561..1330631 Escherichia coli E24377A 5590763 YP_001462441.1 CDS cvrA NC_009801.1 1331017 1332753 R the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter complement(1331017..1332753) Escherichia coli E24377A 5589723 YP_001462442.1 CDS ldcA NC_009801.1 1332848 1333762 R catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A complement(1332848..1333762) Escherichia coli E24377A 5590451 YP_001462443.1 CDS mltE NC_009801.1 1333748 1334473 D identified by similarity to SP:P76009; match to protein family HMM PF01464; membrane-bound lytic murein transglycosylase E 1333748..1334473 Escherichia coli E24377A 5586066 YP_001462444.1 CDS EcE24377A_1339 NC_009801.1 1334475 1335209 R identified by match to protein family HMM PF07238; match to protein family HMM PF07317; type IV pilus assembly protein PilZ complement(1334475..1335209) Escherichia coli E24377A 5587459 YP_001462445.1 CDS EcE24377A_1341 NC_009801.1 1335410 1335664 D identified by match to protein family HMM PF04226; transglycosylase-associated protein 1335410..1335664 Escherichia coli E24377A 5588689 YP_001462446.1 CDS EcE24377A_1340 NC_009801.1 1335464 1335733 R identified by similarity to GB:AAT83486.1; hypothetical protein complement(1335464..1335733) Escherichia coli E24377A 5590835 YP_001462447.1 CDS EcE24377A_1342 NC_009801.1 1335842 1336282 D identified by similarity to GB:ABB66472.1; hypothetical protein 1335842..1336282 Escherichia coli E24377A 5586909 YP_001462448.1 CDS treA NC_009801.1 1336361 1338058 R periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase complement(1336361..1338058) Escherichia coli E24377A 5586340 YP_001462449.1 CDS dhaM NC_009801.1 1338378 1339796 R phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit DhaM complement(1338378..1339796) Escherichia coli E24377A 5587051 YP_001462450.1 CDS EcE24377A_1345 NC_009801.1 1339807 1340439 R with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL complement(1339807..1340439) Escherichia coli E24377A 5588009 YP_001462451.1 CDS dhaK NC_009801.1 1340450 1341520 R with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK complement(1340450..1341520) Escherichia coli E24377A 5587160 YP_001462452.1 CDS dhaR NC_009801.1 1341748 1343667 D Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1341748..1343667 Escherichia coli E24377A 5585922 YP_001462453.1 CDS EcE24377A_1348 NC_009801.1 1343767 1346652 R identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; outer membrane autotransporter complement(1343767..1346652) Escherichia coli E24377A 5587909 YP_001462454.1 CDS EcE24377A_1349 NC_009801.1 1346997 1347200 D identified by similarity to GB:AAZ88642.1; hypothetical protein 1346997..1347200 Escherichia coli E24377A 5588419 YP_001462455.1 CDS engD NC_009801.1 1347493 1348584 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(1347493..1348584) Escherichia coli E24377A 5586716 YP_001462456.1 CDS pth NC_009801.1 1348701 1349285 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(1348701..1349285) Escherichia coli E24377A 5589295 YP_001462457.1 CDS EcE24377A_1352 NC_009801.1 1349563 1349841 D YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1349563..1349841 Escherichia coli E24377A 5588313 YP_001462458.1 CDS ychM NC_009801.1 1349896 1351548 R role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM complement(1349896..1351548) Escherichia coli E24377A 5586517 YP_001462459.1 CDS EcE24377A_1354 NC_009801.1 1351481 1351603 R identified by glimmer; hypothetical protein complement(1351481..1351603) Escherichia coli E24377A 5586041 YP_001462460.1 CDS prs NC_009801.1 1351700 1352647 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1351700..1352647) Escherichia coli E24377A 5589995 YP_001462461.1 CDS ipk NC_009801.1 1352798 1353649 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(1352798..1353649) Escherichia coli E24377A 5587942 YP_001462462.1 CDS lolB NC_009801.1 1353649 1354272 R Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; molecular chaperone LolB complement(1353649..1354272) Escherichia coli E24377A 5589442 YP_001462463.1 CDS hemA NC_009801.1 1354486 1355742 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1354486..1355742 Escherichia coli E24377A 5586780 YP_001462464.1 CDS prfA NC_009801.1 1355784 1356866 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1355784..1356866 Escherichia coli E24377A 5588597 YP_001462465.1 CDS hemK NC_009801.1 1356866 1357699 D HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1356866..1357699 Escherichia coli E24377A 5589355 YP_001462466.1 CDS EcE24377A_1361 NC_009801.1 1357696 1358088 D identified by match to protein family HMM PF04247; transcriptional regulator 1357696..1358088 Escherichia coli E24377A 5589103 YP_001462467.1 CDS sirB1 NC_009801.1 1358092 1358901 D transcriptional regulator 1358092..1358901 Escherichia coli E24377A 5586751 YP_001462468.1 CDS kdsA NC_009801.1 1358937 1359791 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1358937..1359791 Escherichia coli E24377A 5586581 YP_001462469.1 CDS EcE24377A_1364 NC_009801.1 1359940 1360074 R identified by similarity to GB:AAZ88629.1; hypothetical protein complement(1359940..1360074) Escherichia coli E24377A 5587576 YP_001462470.1 CDS EcE24377A_1365 NC_009801.1 1360475 1360609 R identified by similarity to GB:AAZ88629.1; hypothetical protein complement(1360475..1360609) Escherichia coli E24377A 5587705 YP_001462471.1 CDS EcE24377A_1366 NC_009801.1 1360988 1362088 R identified by match to protein family HMM PF01699; match to protein family HMM TIGR00846; calcium/sodium:proton antiporter complement(1360988..1362088) Escherichia coli E24377A 5588218 YP_001462472.1 CDS chaB NC_009801.1 1362358 1362588 D in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1362358..1362588 Escherichia coli E24377A 5588611 YP_001462473.1 CDS EcE24377A_1368 NC_009801.1 1362725 1363441 D identified by match to protein family HMM PF04752; chaC protein 1362725..1363441 Escherichia coli E24377A 5588676 YP_001462474.1 CDS EcE24377A_1369 NC_009801.1 1363485 1363838 R identified by match to protein family HMM PF02635; dsrE family protein complement(1363485..1363838) Escherichia coli E24377A 5587044 YP_001462475.1 CDS EcE24377A_1370 NC_009801.1 1364023 1365417 D hypothetical protein 1364023..1365417 Escherichia coli E24377A 5590104 YP_001462476.1 CDS narL NC_009801.1 1365418 1366068 R two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL complement(1365418..1366068) Escherichia coli E24377A 5588243 YP_001462477.1 CDS narX NC_009801.1 1366061 1367857 R identified by similarity to SP:P10956; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730; nitrate/nitrite sensor protein NarX complement(1366061..1367857) Escherichia coli E24377A 5588585 YP_001462478.1 CDS EcE24377A_1373 NC_009801.1 1367883 1368101 D identified by glimmer; hypothetical protein 1367883..1368101 Escherichia coli E24377A 5588955 YP_001462479.1 CDS narK NC_009801.1 1368196 1369581 D identified by match to protein family HMM PF07690; match to protein family HMM TIGR00886; nitrite extrusion protein 1 1368196..1369581 Escherichia coli E24377A 5587489 YP_001462480.1 CDS narG NC_009801.1 1370102 1373845 D identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; nitrate reductase subunit alpha 1370102..1373845 Escherichia coli E24377A 5589837 YP_001462481.1 CDS narH NC_009801.1 1373842 1375380 D identified by similarity to SP:P11349; match to protein family HMM PF00037; match to protein family HMM TIGR01660; nitrate reductase subunit beta 1373842..1375380 Escherichia coli E24377A 5588229 YP_001462482.1 CDS narJ NC_009801.1 1375377 1376087 D identified by similarity to SP:P0AF26; match to protein family HMM PF02613; match to protein family HMM TIGR00684; nitrate reductase molybdenum cofactor assembly chaperone 1375377..1376087 Escherichia coli E24377A 5589909 YP_001462483.1 CDS narI1 NC_009801.1 1376087 1376764 D identified by similarity to SP:P11350; match to protein family HMM PF02665; match to protein family HMM TIGR00351; respiratory nitrate reductase subunit gamma 1376087..1376764 Escherichia coli E24377A 5587216 YP_001462484.1 CDS purU NC_009801.1 1377844 1378686 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(1377844..1378686) Escherichia coli E24377A 5590220 YP_001462485.1 CDS EcE24377A_1382 NC_009801.1 1378736 1379194 R identified by match to protein family HMM PF02810; hypothetical protein complement(1378736..1379194) Escherichia coli E24377A 5585942 YP_001462486.1 CDS EcE24377A_1383 NC_009801.1 1379307 1380212 D identified by match to protein family HMM PF01734; hypothetical protein 1379307..1380212 Escherichia coli E24377A 5587745 YP_001462487.1 CDS EcE24377A_1384 NC_009801.1 1380304 1381317 D identified by match to protein family HMM PF00072; response regulator of RpoS 1380304..1381317 Escherichia coli E24377A 5589553 YP_001462488.1 CDS galU NC_009801.1 1381519 1382427 D together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 1381519..1382427 Escherichia coli E24377A 5586206 YP_001462489.1 CDS hns NC_009801.1 1382571 1382984 R identified by similarity to SP:P0ACF8; match to protein family HMM PF00816; global DNA-binding transcriptional dual regulator H-NS complement(1382571..1382984) Escherichia coli E24377A 5589795 YP_001462490.1 CDS tdk NC_009801.1 1383589 1384206 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1383589..1384206 Escherichia coli E24377A 5588386 YP_001462491.1 CDS adhE NC_009801.1 1385501 1388182 R identified by similarity to SP:P0A9Q7; match to protein family HMM PF00171; match to protein family HMM PF00465; bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(1385501..1388182) Escherichia coli E24377A 5587841 YP_001462492.1 CDS EcE24377A_1390 NC_009801.1 1388659 1389306 D identified by match to protein family HMM PF01914; match to protein family HMM TIGR00427; hypothetical protein 1388659..1389306 Escherichia coli E24377A 5589806 YP_001462493.1 CDS oppA NC_009801.1 1390044 1391675 D identified by match to protein family HMM PF00496; oligopeptide ABC transporter periplasmic oligopeptide-binding protein 1390044..1391675 Escherichia coli E24377A 5586032 YP_001462494.1 CDS oppB NC_009801.1 1391761 1392681 D identified by match to protein family HMM PF00528; oligopeptide transporter permease 1391761..1392681 Escherichia coli E24377A 5585935 YP_001462495.1 CDS oppC NC_009801.1 1392696 1393604 D identified by match to protein family HMM PF00528; oligopeptide ABC transporter permease OppC 1392696..1393604 Escherichia coli E24377A 5587124 YP_001462496.1 CDS oppD NC_009801.1 1393616 1394629 D identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; oligopeptide ABC transporter ATP-binding protein 1393616..1394629 Escherichia coli E24377A 5590628 YP_001462497.1 CDS oppF NC_009801.1 1394626 1395630 D identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; oligopeptide ABC transporter ATP-binding protein OppF 1394626..1395630 Escherichia coli E24377A 5588846 YP_001462498.1 CDS EcE24377A_1396 NC_009801.1 1395683 1396012 R highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein complement(1395683..1396012) Escherichia coli E24377A 5590583 YP_001462499.1 CDS cls NC_009801.1 1396047 1397507 R catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase complement(1396047..1397507) Escherichia coli E24377A 5587435 YP_001462500.1 CDS kch NC_009801.1 1397878 1399131 R identified by similarity to SP:P31069; match to protein family HMM PF02254; match to protein family HMM PF07885; voltage-gated potassium channel complement(1397878..1399131) Escherichia coli E24377A 5586491 YP_001462501.1 CDS EcE24377A_1399 NC_009801.1 1399430 1399726 R unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein complement(1399430..1399726) Escherichia coli E24377A 5589592 YP_001462502.1 CDS EcE24377A_1400 NC_009801.1 1401710 1402378 D phage N-6-adenine-methyltransferase 1401710..1402378 Escherichia coli E24377A 5588372 YP_001462503.1 CDS EcE24377A_1401 NC_009801.1 1402742 1403734 D identified by similarity to GB:AAZ87752.1; hypothetical protein 1402742..1403734 Escherichia coli E24377A 5587836 YP_001462504.1 CDS EcE24377A_1402 NC_009801.1 1404867 1405076 D identified by glimmer; hypothetical protein 1404867..1405076 Escherichia coli E24377A 5585943 YP_001462505.1 CDS EcE24377A_1403 NC_009801.1 1406063 1406773 D hypothetical protein 1406063..1406773 Escherichia coli E24377A 5587719 YP_001462506.1 CDS EcE24377A_1404 NC_009801.1 1407125 1409257 D identified by match to protein family HMM TIGR02675; hypothetical protein 1407125..1409257 Escherichia coli E24377A 5586470 YP_001462507.1 CDS EcE24377A_1405 NC_009801.1 1409617 1410006 D identified by match to protein family HMM PF01527; IS66 family orf1 1409617..1410006 Escherichia coli E24377A 5589032 YP_001462508.1 CDS EcE24377A_1406 NC_009801.1 1410003 1410350 D identified by match to protein family HMM PF05717; IS66 family orf2 1410003..1410350 Escherichia coli E24377A 5590001 YP_001462509.1 CDS EcE24377A_1407 NC_009801.1 1410400 1411938 D identified by match to protein family HMM PF03050; IS66 family transposase 1410400..1411938 Escherichia coli E24377A 5588358 YP_001462510.1 CDS EcE24377A_1408 NC_009801.1 1411961 1412644 D hypothetical protein 1411961..1412644 Escherichia coli E24377A 5588511 YP_001462511.1 CDS EcE24377A_1409 NC_009801.1 1412677 1414197 R identified by match to protein family HMM PF00239; match to protein family HMM PF07508; recombinase complement(1412677..1414197) Escherichia coli E24377A 5587462 YP_001462512.1 CDS tonB NC_009801.1 1414288 1415007 D membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter 1414288..1415007 Escherichia coli E24377A 5586976 YP_001462513.1 CDS yciA NC_009801.1 1415047 1415445 R YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase of proteins; acyl-CoA thioester hydrolase complement(1415047..1415445) Escherichia coli E24377A 5586239 YP_001462514.1 CDS ispZ NC_009801.1 1415550 1416089 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(1415550..1416089) Escherichia coli E24377A 5588538 YP_001462515.1 CDS EcE24377A_1413 NC_009801.1 1416119 1416862 R identified by match to protein family HMM PF06790; hypothetical protein complement(1416119..1416862) Escherichia coli E24377A 5589338 YP_001462516.1 CDS ompW NC_009801.1 1417219 1417857 D receptor for colicin S4; outer membrane protein W 1417219..1417857 Escherichia coli E24377A 5589666 YP_001462517.1 CDS EcE24377A_1415 NC_009801.1 1417903 1419033 R identified by match to protein family HMM PF00589; match to protein family HMM PF09003; phage integrase site specific recombinase complement(1417903..1419033) Escherichia coli E24377A 5587807 YP_001462518.1 CDS EcE24377A_1416 NC_009801.1 1419324 1421795 R identified by match to protein family HMM PF00929; exonuclease complement(1419324..1421795) Escherichia coli E24377A 5589794 YP_001462519.1 CDS EcE24377A_1417 NC_009801.1 1421767 1421874 D identified by glimmer; hypothetical protein 1421767..1421874 Escherichia coli E24377A 5586674 YP_001462520.1 CDS EcE24377A_1418 NC_009801.1 1421875 1422078 R identified by match to protein family HMM PF07358; hypothetical protein complement(1421875..1422078) Escherichia coli E24377A 5588159 YP_001462521.1 CDS EcE24377A_1419 NC_009801.1 1422274 1423128 R identified by match to protein family HMM TIGR02681; Rha family phage regulatory protein complement(1422274..1423128) Escherichia coli E24377A 5586024 YP_001462522.1 CDS EcE24377A_1420 NC_009801.1 1424416 1424562 R identified by similarity to GB:CAD05612.1; hypothetical protein complement(1424416..1424562) Escherichia coli E24377A 5588109 YP_001462523.1 CDS EcE24377A_1421 NC_009801.1 1424564 1424812 R identified by match to protein family HMM PF07151; hypothetical protein complement(1424564..1424812) Escherichia coli E24377A 5590378 YP_001462524.1 CDS EcE24377A_1422 NC_009801.1 1425368 1425622 D identified by similarity to SP:P06965; DNA-binding transcriptional regulator DicC 1425368..1425622 Escherichia coli E24377A 5588202 YP_001462525.1 CDS EcE24377A_1423 NC_009801.1 1425606 1426157 D identified by match to protein family HMM PF06254; hypothetical protein 1425606..1426157 Escherichia coli E24377A 5586269 YP_001462526.1 CDS EcE24377A_1424 NC_009801.1 1426129 1427169 D identified by similarity to GB:AAW62196.1; hypothetical protein 1426129..1427169 Escherichia coli E24377A 5589176 YP_001462527.1 CDS EcE24377A_1425 NC_009801.1 1426958 1427623 D hypothetical protein 1426958..1427623 Escherichia coli E24377A 5589066 YP_001462528.1 CDS EcE24377A_1426 NC_009801.1 1427653 1428048 D identified by similarity to GB:BAB35696.1; match to protein family HMM PF06163; hypothetical protein 1427653..1428048 Escherichia coli E24377A 5590705 YP_001462529.1 CDS EcE24377A_1427 NC_009801.1 1428051 1428341 D hypothetical protein 1428051..1428341 Escherichia coli E24377A 5588380 YP_001462530.1 CDS EcE24377A_1429 NC_009801.1 1428722 1428934 D identified by similarity to GB:BAB35372.1; hypothetical protein 1428722..1428934 Escherichia coli E24377A 5586325 YP_001462531.1 CDS EcE24377A_1430 NC_009801.1 1429524 1430456 R identified by similarity to GB:CAD05601.1; hypothetical protein complement(1429524..1430456) Escherichia coli E24377A 5588175 YP_001462532.1 CDS EcE24377A_1431 NC_009801.1 1431077 1431193 D identified by glimmer; hypothetical protein 1431077..1431193 Escherichia coli E24377A 5590737 YP_001462533.1 CDS EcE24377A_1433 NC_009801.1 1431258 1431506 D identified by similarity to GB:ABB61576.1; hypothetical protein 1431258..1431506 Escherichia coli E24377A 5588970 YP_001462534.1 CDS EcE24377A_1434 NC_009801.1 1431853 1432902 D identified by similarity to GB:AAN79892.1; match to protein family HMM PF06914; hypothetical protein 1431853..1432902 Escherichia coli E24377A 5588902 YP_001462535.1 CDS EcE24377A_1435 NC_009801.1 1432915 1433274 D identified by similarity to SP:Q9MCN8; match to protein family HMM PF05866; crossover junction endodeoxyribonuclease RusA-like protein 1432915..1433274 Escherichia coli E24377A 5586831 YP_001462536.1 CDS EcE24377A_1436 NC_009801.1 1433271 1433960 D identified by match to protein family HMM PF06323; phage antitermination protein Q 1433271..1433960 Escherichia coli E24377A 5586652 YP_001462537.1 CDS EcE24377A_1437 NC_009801.1 1434030 1434869 D identified by match to protein family HMM PF00069; protein kinase domain-containing protein 1434030..1434869 Escherichia coli E24377A 5587974 YP_001462538.1 CDS EcE24377A_1438 NC_009801.1 1434866 1435609 D identified by glimmer; hypothetical protein 1434866..1435609 Escherichia coli E24377A 5587778 YP_001462539.1 CDS EcE24377A_1439 NC_009801.1 1435742 1436026 D identified by similarity to GB:CAE15837.1; hypothetical protein 1435742..1436026 Escherichia coli E24377A 5589946 YP_001462540.1 CDS EcE24377A_1440 NC_009801.1 1436177 1437223 D identified by match to protein family HMM PF01555; DNA methylase 1436177..1437223 Escherichia coli E24377A 5586485 YP_001462541.1 CDS EcE24377A_1443 NC_009801.1 1438724 1439074 D identified by similarity to GB:CAB93764.1; hypothetical protein 1438724..1439074 Escherichia coli E24377A 5586562 YP_001462542.1 CDS EcE24377A_1444 NC_009801.1 1439071 1439322 D identified by glimmer; hypothetical protein 1439071..1439322 Escherichia coli E24377A 5590759 YP_001462543.1 CDS EcE24377A_1445 NC_009801.1 1439331 1440413 D identified by match to protein family HMM PF05136; lambda family phage portal protein 1439331..1440413 Escherichia coli E24377A 5589408 YP_001462544.1 CDS EcE24377A_1446 NC_009801.1 1440410 1440844 D hypothetical protein 1440410..1440844 Escherichia coli E24377A 5586317 YP_001462545.1 CDS EcE24377A_1447 NC_009801.1 1440816 1441031 D identified by glimmer; hypothetical protein 1440816..1441031 Escherichia coli E24377A 5586399 YP_001462546.1 CDS EcE24377A_1448 NC_009801.1 1441015 1441347 D hypothetical protein 1441015..1441347 Escherichia coli E24377A 5588507 YP_001462547.1 CDS EcE24377A_1449 NC_009801.1 1441496 1441693 D hypothetical protein 1441496..1441693 Escherichia coli E24377A 5589748 YP_001462548.1 CDS EcE24377A_1450 NC_009801.1 1441690 1444236 D identified by glimmer; hypothetical protein 1441690..1444236 Escherichia coli E24377A 5589499 YP_001462549.1 CDS EcE24377A_1451 NC_009801.1 1444283 1445074 D identified by glimmer; hypothetical protein 1444283..1445074 Escherichia coli E24377A 5588714 YP_001462550.1 CDS EcE24377A_1452 NC_009801.1 1445087 1445626 D identified by match to protein family HMM PF02413; hypothetical protein 1445087..1445626 Escherichia coli E24377A 5590302 YP_001462551.1 CDS EcE24377A_1453 NC_009801.1 1447274 1447834 R hypothetical protein complement(1447274..1447834) Escherichia coli E24377A 5586955 YP_001462552.1 CDS EcE24377A_1454 NC_009801.1 1448307 1448423 D identified by match to protein family HMM TIGR03304; hypothetical protein 1448307..1448423 Escherichia coli E24377A 5589179 YP_001462553.1 CDS EcE24377A_1455 NC_009801.1 1448483 1448989 R identified by match to protein family HMM PF05974; hypothetical protein complement(1448483..1448989) Escherichia coli E24377A 5588085 YP_001462554.1 CDS yciF NC_009801.1 1449035 1449535 R identified by match to protein family HMM PF05974; hypothetical protein complement(1449035..1449535) Escherichia coli E24377A 5589274 YP_001462555.1 CDS EcE24377A_1457 NC_009801.1 1449593 1449787 R identified by similarity to GB:AAX64977.1; hypothetical protein complement(1449593..1449787) Escherichia coli E24377A 5590569 YP_001462556.1 CDS EcE24377A_1458 NC_009801.1 1449621 1449800 R identified by similarity to OMNI:NTL01EC01230; hypothetical protein complement(1449621..1449800) Escherichia coli E24377A 5590481 YP_001462557.1 CDS trpA NC_009801.1 1450181 1450987 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1450181..1450987) Escherichia coli E24377A 5586791 YP_001462558.1 CDS trpB NC_009801.1 1450987 1452180 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1450987..1452180) Escherichia coli E24377A 5588370 YP_001462559.1 CDS trpC NC_009801.1 1452192 1453550 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1452192..1453550) Escherichia coli E24377A 5589778 YP_001462560.1 CDS trpD NC_009801.1 1453554 1455149 R bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase complement(1453554..1455149) Escherichia coli E24377A 5586212 YP_001462561.1 CDS EcE24377A_1464 NC_009801.1 1455072 1455170 D identified by glimmer; hypothetical protein 1455072..1455170 Escherichia coli E24377A 5589445 YP_001462562.1 CDS trpE NC_009801.1 1455149 1456711 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1455149..1456711) Escherichia coli E24377A 5590594 YP_001462563.1 CDS EcE24377A_1465 NC_009801.1 1457006 1457866 D identified by match to protein family HMM PF02811; phosphoesterase 1457006..1457866 Escherichia coli E24377A 5587685 YP_001462564.1 CDS EcE24377A_1466 NC_009801.1 1457863 1458483 D identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; hypothetical protein 1457863..1458483 Escherichia coli E24377A 5586184 YP_001462565.1 CDS rluB NC_009801.1 1458584 1459456 D catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1458584..1459456 Escherichia coli E24377A 5586238 YP_001462566.1 CDS btuR NC_009801.1 1459496 1460086 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(1459496..1460086) Escherichia coli E24377A 5589391 YP_001462567.1 CDS EcE24377A_1470 NC_009801.1 1460083 1460841 R identified by match to protein family HMM PF00106; match to protein family HMM PF08659; short chain dehydrogenase complement(1460083..1460841) Escherichia coli E24377A 5589239 YP_001462568.1 CDS sohB NC_009801.1 1461061 1462110 D SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1461061..1462110 Escherichia coli E24377A 5587058 YP_001462569.1 CDS EcE24377A_1473 NC_009801.1 1462080 1462172 D identified by glimmer; hypothetical protein 1462080..1462172 Escherichia coli E24377A 5590398 YP_001462570.1 CDS EcE24377A_1472 NC_009801.1 1462146 1462397 R hypothetical protein complement(1462146..1462397) Escherichia coli E24377A 5586799 YP_001462571.1 CDS topA NC_009801.1 1462777 1465374 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1462777..1465374 Escherichia coli E24377A 5588168 YP_001462572.1 CDS cysB NC_009801.1 1465584 1466558 D LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1465584..1466558 Escherichia coli E24377A 5589929 YP_001462573.1 CDS EcE24377A_1476 NC_009801.1 1466877 1467017 D hypothetical protein 1466877..1467017 Escherichia coli E24377A 5590876 YP_001462574.1 CDS EcE24377A_1477 NC_009801.1 1467008 1467187 D hypothetical protein 1467008..1467187 Escherichia coli E24377A 5586252 YP_001462575.1 CDS acnA NC_009801.1 1467560 1470235 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1467560..1470235 Escherichia coli E24377A 5589997 YP_001462576.1 CDS ribA NC_009801.1 1470299 1470889 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(1470299..1470889) Escherichia coli E24377A 5588747 YP_001462577.1 CDS pgpB NC_009801.1 1471059 1471823 D identified by similarity to SP:P0A924; match to protein family HMM PF01569; phosphatidylglycerophosphatase B 1471059..1471823 Escherichia coli E24377A 5590463 YP_001462578.1 CDS EcE24377A_1481 NC_009801.1 1471972 1472280 D identified by match to protein family HMM PF06305; hypothetical protein 1471972..1472280 Escherichia coli E24377A 5587612 YP_001462579.1 CDS EcE24377A_1482 NC_009801.1 1472287 1473456 D identified by match to protein family HMM PF07719; tetratricopeptide repeat protein 1472287..1473456 Escherichia coli E24377A 5588164 YP_001462580.1 CDS EcE24377A_1483 NC_009801.1 1473490 1473633 R identified by glimmer; hypothetical protein complement(1473490..1473633) Escherichia coli E24377A 5590571 YP_001462581.1 CDS pyrF NC_009801.1 1473649 1474386 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1473649..1474386 Escherichia coli E24377A 5588363 YP_001462582.1 CDS EcE24377A_1485 NC_009801.1 1474386 1474712 D involved in start site selection during the initiation of translation; translation initiation factor Sui1 1474386..1474712 Escherichia coli E24377A 5589369 YP_001462583.1 CDS EcE24377A_1486 NC_009801.1 1474838 1475056 R identified by similarity to SP:P0ADA7; lipoprotein complement(1474838..1475056) Escherichia coli E24377A 5589537 YP_001462584.1 CDS EcE24377A_1487 NC_009801.1 1475325 1476074 R identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; DeoR family transcriptional regulator complement(1475325..1476074) Escherichia coli E24377A 5586393 YP_001462585.1 CDS EcE24377A_1488 NC_009801.1 1476164 1476346 R hypothetical protein complement(1476164..1476346) Escherichia coli E24377A 5589446 YP_001462586.1 CDS EcE24377A_1489 NC_009801.1 1476484 1478469 R c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator complement(1476484..1478469) Escherichia coli E24377A 5589676 YP_001462587.1 CDS EcE24377A_1490 NC_009801.1 1478573 1478680 R identified by glimmer; hypothetical protein complement(1478573..1478680) Escherichia coli E24377A 5589378 YP_001462588.1 CDS rnb NC_009801.1 1478704 1480638 R Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II complement(1478704..1480638) Escherichia coli E24377A 5589681 YP_001462589.1 CDS EcE24377A_1492 NC_009801.1 1480706 1481911 R hypothetical protein complement(1480706..1481911) Escherichia coli E24377A 5587910 YP_001462590.1 CDS EcE24377A_1493 NC_009801.1 1481862 1481969 R identified by glimmer; hypothetical protein complement(1481862..1481969) Escherichia coli E24377A 5586336 YP_001462591.1 CDS fabI NC_009801.1 1481978 1482766 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase complement(1481978..1482766) Escherichia coli E24377A 5589635 YP_001462592.1 CDS EcE24377A_1495 NC_009801.1 1482781 1482879 D identified by glimmer; hypothetical protein 1482781..1482879 Escherichia coli E24377A 5586605 YP_001462593.1 CDS EcE24377A_1496 NC_009801.1 1483134 1483484 R identified by match to protein family HMM PF04480; hypothetical protein complement(1483134..1483484) Escherichia coli E24377A 5590820 YP_001462594.1 CDS sapF NC_009801.1 1483555 1484361 R identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein SapF complement(1483555..1484361) Escherichia coli E24377A 5587794 YP_001462595.1 CDS sapD NC_009801.1 1484363 1485355 R identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; peptide ABC transporter ATP-binding protein SapD complement(1484363..1485355) Escherichia coli E24377A 5588733 YP_001462596.1 CDS sapC NC_009801.1 1485355 1486245 R identified by match to protein family HMM PF00528; peptide ABC transporter permease SapC complement(1485355..1486245) Escherichia coli E24377A 5590252 YP_001462597.1 CDS sapB NC_009801.1 1486232 1487197 R identified by match to protein family HMM PF00528; peptide ABC transporter permease SapB complement(1486232..1487197) Escherichia coli E24377A 5590190 YP_001462598.1 CDS sapA NC_009801.1 1487194 1488837 R identified by match to protein family HMM PF00496; peptide ABC transporter periplasmic peptide-binding protein complement(1487194..1488837) Escherichia coli E24377A 5590636 YP_001462599.1 CDS EcE24377A_1503 NC_009801.1 1489043 1489168 D identified by glimmer; hypothetical protein 1489043..1489168 Escherichia coli E24377A 5586814 YP_001462600.1 CDS EcE24377A_1502 NC_009801.1 1489150 1489395 R hypothetical protein complement(1489150..1489395) Escherichia coli E24377A 5589689 YP_001462601.1 CDS EcE24377A_1504 NC_009801.1 1489411 1489521 R identified by glimmer; hypothetical protein complement(1489411..1489521) Escherichia coli E24377A 5589954 YP_001462602.1 CDS EcE24377A_1505 NC_009801.1 1489529 1490914 R identified by match to protein family HMM PF00324; amino acid permease complement(1489529..1490914) Escherichia coli E24377A 5589866 YP_001462603.1 CDS puuA NC_009801.1 1491217 1492635 R identified by similarity to SP:P78061; match to protein family HMM PF00120; glutamate--putrescine ligase complement(1491217..1492635) Escherichia coli E24377A 5588490 YP_001462604.1 CDS EcE24377A_1507 NC_009801.1 1492823 1492957 R identified by glimmer; hypothetical protein complement(1492823..1492957) Escherichia coli E24377A 5586989 YP_001462605.1 CDS puuD NC_009801.1 1492847 1493611 D catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate; gamma-glutamyl-gamma-aminobutyrate hydrolase 1492847..1493611 Escherichia coli E24377A 5589767 YP_001462606.1 CDS puuR NC_009801.1 1493638 1494195 D regulates genes involved in putrescine degradation; DNA-binding transcriptional repressor PuuR 1493638..1494195 Escherichia coli E24377A 5589306 YP_001462607.1 CDS puuC NC_009801.1 1494345 1495832 D catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 1494345..1495832 Escherichia coli E24377A 5586521 YP_001462608.1 CDS puuB NC_009801.1 1495834 1497114 D identified by similarity to SP:P37906; match to protein family HMM PF01266; gamma-glutamylputrescine oxidoreductase 1495834..1497114 Escherichia coli E24377A 5589210 YP_001462609.1 CDS gabT1 NC_009801.1 1497152 1498417 D putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 1497152..1498417 Escherichia coli E24377A 5586616 YP_001462610.1 CDS pspF NC_009801.1 1498537 1499514 R transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator complement(1498537..1499514) Escherichia coli E24377A 5586982 YP_001462611.1 CDS pspA NC_009801.1 1499681 1500349 D involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1499681..1500349 Escherichia coli E24377A 5586007 YP_001462612.1 CDS pspB NC_009801.1 1500403 1500627 D acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1500403..1500627 Escherichia coli E24377A 5589020 YP_001462613.1 CDS pspC NC_009801.1 1500627 1500986 D with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1500627..1500986 Escherichia coli E24377A 5586190 YP_001462614.1 CDS pspD NC_009801.1 1500995 1501216 D identified by match to protein family HMM TIGR02979; peripheral inner membrane phage-shock protein 1500995..1501216 Escherichia coli E24377A 5589384 YP_001462615.1 CDS pspE NC_009801.1 1501291 1501605 D rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1501291..1501605 Escherichia coli E24377A 5588195 YP_001462616.1 CDS EcE24377A_1519 NC_009801.1 1501818 1503497 D identified by match to protein family HMM PF00128; alpha amylase 1501818..1503497 Escherichia coli E24377A 5588142 YP_001462617.1 CDS EcE24377A_1520 NC_009801.1 1503511 1504803 D identified by match to protein family HMM PF01547; sugar ABC transporter periplasmic sugar-binding protein 1503511..1504803 Escherichia coli E24377A 5588081 YP_001462618.1 CDS EcE24377A_1521 NC_009801.1 1504824 1505705 D identified by match to protein family HMM PF00528; sugar ABC transporter permease 1504824..1505705 Escherichia coli E24377A 5590212 YP_001462619.1 CDS EcE24377A_1522 NC_009801.1 1505692 1506534 D identified by match to protein family HMM PF00528; sugar ABC transporter permease 1505692..1506534 Escherichia coli E24377A 5587006 YP_001462620.1 CDS EcE24377A_1523 NC_009801.1 1506565 1507617 D identified by match to protein family HMM PF00107; zinc-binding dehydrogenase oxidoreductase 1506565..1507617 Escherichia coli E24377A 5589235 YP_001462621.1 CDS EcE24377A_1524 NC_009801.1 1507636 1508424 D identified by match to protein family HMM PF01261; AP endonuclease 1507636..1508424 Escherichia coli E24377A 5590732 YP_001462622.1 CDS EcE24377A_1525 NC_009801.1 1508434 1509489 D identified by match to protein family HMM PF01408; match to protein family HMM PF02894; gfo/idh/mocA family protein 1508434..1509489 Escherichia coli E24377A 5587765 YP_001462623.1 CDS EcE24377A_1527 NC_009801.1 1509486 1511753 D identified by match to protein family HMM PF03632; match to protein family HMM PF03633; match to protein family HMM PF03636; glycosyl hydrolase 1509486..1511753 Escherichia coli E24377A 5586196 YP_001462624.1 CDS EcE24377A_1526 NC_009801.1 1511640 1511738 R identified by glimmer; hypothetical protein complement(1511640..1511738) Escherichia coli E24377A 5587050 YP_001462625.1 CDS pgmB NC_009801.1 1511750 1512409 D identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; match to protein family HMM TIGR01990; match to protein family HMM TIGR02009; beta-phosphoglucomutase 1511750..1512409 Escherichia coli E24377A 5586534 YP_001462626.1 CDS EcE24377A_1529 NC_009801.1 1512423 1513505 D identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402; sugar ABC transporter ATP-binding protein 1512423..1513505 Escherichia coli E24377A 5589068 YP_001462627.1 CDS ompG NC_009801.1 1513550 1514455 D identified by match to protein family HMM TIGR03304; outer membrane protein G 1513550..1514455 Escherichia coli E24377A 5589950 YP_001462628.1 CDS EcE24377A_1531 NC_009801.1 1514566 1515564 R identified by match to protein family HMM PF00356; match to protein family HMM PF00532; LacI family transcriptional regulator complement(1514566..1515564) Escherichia coli E24377A 5589128 YP_001462629.1 CDS EcE24377A_1532 NC_009801.1 1515719 1517116 D identified by match to protein family HMM PF04317; hypothetical protein 1515719..1517116 Escherichia coli E24377A 5587780 YP_001462630.1 CDS EcE24377A_1533 NC_009801.1 1517113 1518174 D identified by similarity to GB:ABB66349.1; match to protein family HMM PF05128; match to protein family HMM TIGR01620; hypothetical protein 1517113..1518174 Escherichia coli E24377A 5587447 YP_001462631.1 CDS tyrR NC_009801.1 1518322 1519863 D regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1518322..1519863 Escherichia coli E24377A 5590261 YP_001462632.1 CDS tpx NC_009801.1 1519907 1520413 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(1519907..1520413) Escherichia coli E24377A 5587650 YP_001462633.1 CDS EcE24377A_1537 NC_009801.1 1520532 1521497 D identified by match to protein family HMM PF01188; match to protein family HMM PF02746; mandelate racemase/muconate lactonizing enzyme family protein 1520532..1521497 Escherichia coli E24377A 5589968 YP_001462634.1 CDS EcE24377A_1536 NC_009801.1 1521472 1522200 R identified by match to protein family HMM PF00246; murein peptide amidase A complement(1521472..1522200) Escherichia coli E24377A 5589145 YP_001462635.1 CDS EcE24377A_1538 NC_009801.1 1522510 1523148 R identified by match to protein family HMM PF05368; NmrA family protein complement(1522510..1523148) Escherichia coli E24377A 5586434 YP_001462636.1 CDS EcE24377A_1539 NC_009801.1 1523166 1524098 R identified by similarity to GB:BAC59941.1; hypothetical protein complement(1523166..1524098) Escherichia coli E24377A 5589668 YP_001462637.1 CDS EcE24377A_1540 NC_009801.1 1524098 1525018 R hypothetical protein complement(1524098..1525018) Escherichia coli E24377A 5587990 YP_001462638.1 CDS EcE24377A_1541 NC_009801.1 1525156 1526055 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1525156..1526055 Escherichia coli E24377A 5589132 YP_001462639.1 CDS mppA NC_009801.1 1526392 1528005 D identified by match to protein family HMM PF00496; periplasmic murein peptide-binding protein 1526392..1528005 Escherichia coli E24377A 5589706 YP_001462640.1 CDS EcE24377A_1543 NC_009801.1 1528056 1529087 R identified by match to protein family HMM PF00924; small conductance mechanosensitive ion channel (MscS) family protein complement(1528056..1529087) Escherichia coli E24377A 5586597 YP_001462641.1 CDS uspE NC_009801.1 1529638 1530588 R with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE complement(1529638..1530588) Escherichia coli E24377A 5588383 YP_001462642.1 CDS fnr NC_009801.1 1530740 1531492 R Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator complement(1530740..1531492) Escherichia coli E24377A 5587256 YP_001462643.1 CDS abgT NC_009801.1 1532209 1533735 R identified by similarity to SP:P46133; match to protein family HMM PF03806; match to protein family HMM TIGR00819; aminobenzoyl-glutamate transporter complement(1532209..1533735) Escherichia coli E24377A 5586394 YP_001462644.1 CDS abgB NC_009801.1 1533772 1535217 R identified by similarity to SP:P76052; match to protein family HMM PF01546; match to protein family HMM TIGR01891; aminobenzoyl-glutamate utilization protein B complement(1533772..1535217) Escherichia coli E24377A 5590415 YP_001462645.1 CDS abgA NC_009801.1 1535217 1536527 R identified by similarity to SP:P77357; match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; aminobenzoyl-glutamate utilization protein A complement(1535217..1536527) Escherichia coli E24377A 5588307 YP_001462646.1 CDS EcE24377A_1551 NC_009801.1 1536502 1536606 R identified by glimmer; hypothetical protein complement(1536502..1536606) Escherichia coli E24377A 5588634 YP_001462647.1 CDS EcE24377A_1552 NC_009801.1 1536603 1536704 R identified by glimmer; hypothetical protein complement(1536603..1536704) Escherichia coli E24377A 5589691 YP_001462648.1 CDS EcE24377A_1553 NC_009801.1 1536703 1537611 D identified by similarity to SP:P77744; match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator 1536703..1537611 Escherichia coli E24377A 5586598 YP_001462649.1 CDS EcE24377A_1554 NC_009801.1 1537941 1538504 D identified by match to protein family HMM PF01713; Smr domain-containing protein 1537941..1538504 Escherichia coli E24377A 5587467 YP_001462650.1 CDS EcE24377A_1555 NC_009801.1 1538525 1539817 R identified by match to protein family HMM PF00990; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; sensory box-containing diguanylate cyclase complement(1538525..1539817) Escherichia coli E24377A 5589041 YP_001462651.1 CDS zntB NC_009801.1 1540012 1540995 D identified by match to protein family HMM PF01544; zinc transporter 1540012..1540995 Escherichia coli E24377A 5587546 YP_001462652.1 CDS dbpA NC_009801.1 1541473 1542846 D exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1541473..1542846 Escherichia coli E24377A 5589089 YP_001462653.1 CDS EcE24377A_1558 NC_009801.1 1542975 1543910 R TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase complement(1542975..1543910) Escherichia coli E24377A 5589496 YP_001462654.1 CDS uspF NC_009801.1 1544086 1544520 R identified by similarity to SP:P37903; match to protein family HMM PF00582; universal stress protein F complement(1544086..1544520) Escherichia coli E24377A 5588251 YP_001462655.1 CDS ompN NC_009801.1 1544661 1545794 R identified by similarity to SP:P77747; match to protein family HMM PF00267; outer membrane protein N complement(1544661..1545794) Escherichia coli E24377A 5588612 YP_001462656.1 CDS ydbK NC_009801.1 1546161 1549685 R identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176; pyruvate-flavodoxin oxidoreductase complement(1546161..1549685) Escherichia coli E24377A 5589265 YP_001462657.1 CDS EcE24377A_1562 NC_009801.1 1549695 1549826 R identified by glimmer; hypothetical protein complement(1549695..1549826) Escherichia coli E24377A 5588452 YP_001462658.1 CDS EcE24377A_1564 NC_009801.1 1549959 1550225 D lipoprotein 1549959..1550225 Escherichia coli E24377A 5587238 YP_001462659.1 CDS hslJ NC_009801.1 1550222 1550644 R identified by match to protein family HMM PF03724; heat-inducible protein complement(1550222..1550644) Escherichia coli E24377A 5587300 YP_001462660.1 CDS idhA NC_009801.1 1550755 1551744 R identified by similarity to SP:P52643; match to protein family HMM PF00389; match to protein family HMM PF02826; D-lactate dehydrogenase complement(1550755..1551744) Escherichia coli E24377A 5589982 YP_001462661.1 CDS EcE24377A_1566 NC_009801.1 1551952 1554591 D identified by similarity to SP:P52645; hypothetical protein 1551952..1554591 Escherichia coli E24377A 5590767 YP_001462662.1 CDS EcE24377A_1567 NC_009801.1 1554588 1554773 D lipoprotein 1554588..1554773 Escherichia coli E24377A 5590832 YP_001462663.1 CDS EcE24377A_1568 NC_009801.1 1554781 1555107 D identified by similarity to GB:AAN80294.1; match to protein family HMM PF07027; hypothetical protein 1554781..1555107 Escherichia coli E24377A 5587694 YP_001462664.1 CDS feaR NC_009801.1 1555279 1556184 R activator of genes involved in phenylacetic acid catabolism; DNA-binding transcriptional activator FeaR complement(1555279..1556184) Escherichia coli E24377A 5588275 YP_001462665.1 CDS feaB NC_009801.1 1556420 1557919 D identified by similarity to SP:P80668; match to protein family HMM PF00171; phenylacetaldehyde dehydrogenase 1556420..1557919 Escherichia coli E24377A 5588851 YP_001462666.1 CDS tynA NC_009801.1 1557977 1560250 R catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine; tyramine oxidase complement(1557977..1560250) Escherichia coli E24377A 5588329 YP_001462667.1 CDS paaN NC_009801.1 1560498 1562543 R catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase complement(1560498..1562543) Escherichia coli E24377A 5586167 YP_001462668.1 CDS paaA NC_009801.1 1562828 1563757 D with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; phenylacetate-CoA oxygenase subunit PaaA 1562828..1563757 Escherichia coli E24377A 5586158 YP_001462669.1 CDS paaB NC_009801.1 1563769 1564056 D with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; phenylacetate-CoA oxygenase subunit PaaB 1563769..1564056 Escherichia coli E24377A 5587131 YP_001462670.1 CDS paaI NC_009801.1 1564065 1564811 D identified by match to protein family HMM PF05138; match to protein family HMM TIGR02158; phenylacetate-CoA oxygenase subunit PaaI 1564065..1564811 Escherichia coli E24377A 5587161 YP_001462671.1 CDS paaJ NC_009801.1 1564826 1565323 D identified by match to protein family HMM PF01883; match to protein family HMM TIGR02159; phenylacetate-CoA oxygenase subunit PaaJ 1564826..1565323 Escherichia coli E24377A 5589130 YP_001462672.1 CDS paaK NC_009801.1 1565331 1566401 D identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM TIGR02160; phenylacetate-CoA oxygenase/reductase subunit PaaK 1565331..1566401 Escherichia coli E24377A 5589064 YP_001462673.1 CDS EcE24377A_1578 NC_009801.1 1566398 1567165 D identified by match to protein family HMM PF00378; enoyl-CoA hydratase 1566398..1567165 Escherichia coli E24377A 5590518 YP_001462674.1 CDS paaB NC_009801.1 1567165 1567953 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1567165..1567953 Escherichia coli E24377A 5586488 YP_001462675.1 CDS paaC NC_009801.1 1567955 1569382 D converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase 1567955..1569382 Escherichia coli E24377A 5587504 YP_001462676.1 CDS paaD NC_009801.1 1569372 1569794 D identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; match to protein family HMM TIGR02286; phenylacetic acid degradation protein PaaD 1569372..1569794 Escherichia coli E24377A 5590222 YP_001462677.1 CDS pcaF NC_009801.1 1569794 1570999 D catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase 1569794..1570999 Escherichia coli E24377A 5590318 YP_001462678.1 CDS paaF NC_009801.1 1571026 1572339 D identified by match to protein family HMM TIGR02155; phenylacetate-CoA ligase 1571026..1572339 Escherichia coli E24377A 5586880 YP_001462679.1 CDS EcE24377A_1583 NC_009801.1 1572286 1572408 R identified by glimmer; hypothetical protein complement(1572286..1572408) Escherichia coli E24377A 5588349 YP_001462680.1 CDS paaX NC_009801.1 1572440 1573390 D identified by similarity to SP:P76086; match to protein family HMM PF07848; match to protein family HMM PF08223; match to protein family HMM TIGR02277; phenylacetic acid degradation operon negative regulatory protein PaaX 1572440..1573390 Escherichia coli E24377A 5586607 YP_001462681.1 CDS paaY NC_009801.1 1573372 1573962 D identified by match to protein family HMM PF00132; match to protein family HMM TIGR02287; phenylacetic acid degradation protein PaaY 1573372..1573962 Escherichia coli E24377A 5585960 YP_001462682.1 CDS EcE24377A_1587 NC_009801.1 1574194 1575054 D identified by match to protein family HMM PF00248; oxidoreductase 1574194..1575054 Escherichia coli E24377A 5588310 YP_001462683.1 CDS EcE24377A_1589 NC_009801.1 1577595 1578200 D identified by match to protein family HMM PF01066; CDP-alcohol phosphatidyltransferase 1577595..1578200 Escherichia coli E24377A 5587430 YP_001462684.1 CDS cdsA2 NC_009801.1 1578200 1579096 D identified by match to protein family HMM PF01148; phosphatidate cytidylyltransferase 1578200..1579096 Escherichia coli E24377A 5589432 YP_001462685.1 CDS EcE24377A_1591 NC_009801.1 1579112 1580869 D hypothetical protein 1579112..1580869 Escherichia coli E24377A 5586451 YP_001462686.1 CDS EcE24377A_1592 NC_009801.1 1580883 1582175 D identified by match to protein family HMM PF00782; match to protein family HMM PF01569; PAP2 family protein 1580883..1582175 Escherichia coli E24377A 5589116 YP_001462687.1 CDS azoR NC_009801.1 1582226 1582831 R FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase complement(1582226..1582831) Escherichia coli E24377A 5589915 YP_001462688.1 CDS hrpA NC_009801.1 1583032 1586934 D involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1583032..1586934 Escherichia coli E24377A 5589871 YP_001462689.1 CDS EcE24377A_1595 NC_009801.1 1587206 1588006 D identified by match to protein family HMM PF02698; hypothetical protein 1587206..1588006 Escherichia coli E24377A 5589867 YP_001462690.1 CDS aldA NC_009801.1 1588203 1589642 D NAD-linked; aldehyde dehydrogenase 1588203..1589642 Escherichia coli E24377A 5587726 YP_001462691.1 CDS gapC NC_009801.1 1589684 1590685 R identified by similarity to SP:P33898; match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) complement(1589684..1590685) Escherichia coli E24377A 5589755 YP_001462692.1 CDS EcE24377A_1598 NC_009801.1 1590838 1591404 D B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1590838..1591404 Escherichia coli E24377A 5590454 YP_001462693.1 CDS EcE24377A_1599 NC_009801.1 1591649 1591822 D hypothetical protein 1591649..1591822 Escherichia coli E24377A 5589071 YP_001462694.1 CDS EcE24377A_1600 NC_009801.1 1592442 1594082 D identified by similarity to SP:P05704; match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203; methyl-accepting chemotaxis protein III 1592442..1594082 Escherichia coli E24377A 5587324 YP_001462695.1 CDS EcE24377A_1601 NC_009801.1 1594120 1595043 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(1594120..1595043) Escherichia coli E24377A 5587181 YP_001462696.1 CDS EcE24377A_1602 NC_009801.1 1595260 1596603 D identified by similarity to SP:P15747; match to protein family HMM PF07063; hypothetical protein 1595260..1596603 Escherichia coli E24377A 5589939 YP_001462697.1 CDS mdoD NC_009801.1 1596828 1598483 D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1596828..1598483 Escherichia coli E24377A 5587242 YP_001462698.1 CDS EcE24377A_1604 NC_009801.1 1598623 1598847 D identified by similarity to GB:AAN80313.1; match to protein family HMM PF04325; hypothetical protein 1598623..1598847 Escherichia coli E24377A 5586376 YP_001462699.1 CDS rimL NC_009801.1 1598910 1599446 D identified by similarity to SP:P13857; match to protein family HMM PF00583; ribosomal-protein-L7/L12-serine acetyltransferase 1598910..1599446 Escherichia coli E24377A 5587956 YP_001462700.1 CDS EcE24377A_1605 NC_009801.1 1599441 1600421 R identified by similarity to SP:P15644; hypothetical protein complement(1599441..1600421) Escherichia coli E24377A 5589252 YP_001462701.1 CDS tehA NC_009801.1 1600545 1601537 D identified by similarity to SP:P25396; match to protein family HMM PF03595; match to protein family HMM TIGR00816; potassium-tellurite ethidium and proflavin transporter 1600545..1601537 Escherichia coli E24377A 5586211 YP_001462702.1 CDS tehB NC_009801.1 1601534 1602127 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1601534..1602127 Escherichia coli E24377A 5588972 YP_001462703.1 CDS EcE24377A_1609 NC_009801.1 1602431 1603099 D lipoprotein 1602431..1603099 Escherichia coli E24377A 5586947 YP_001462704.1 CDS EcE24377A_1611 NC_009801.1 1603631 1604839 D identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766; IS605 family transposase OrfB 1603631..1604839 Escherichia coli E24377A 5588017 YP_001462705.1 CDS EcE24377A_1612 NC_009801.1 1604879 1606147 R identified by match to protein family HMM PF00860; match to protein family HMM PF03594; match to protein family HMM TIGR00843; benzoate transporter complement(1604879..1606147) Escherichia coli E24377A 5589023 YP_001462706.1 CDS EcE24377A_1613 NC_009801.1 1606146 1606682 D identified by match to protein family HMM PF01381; match to protein family HMM PF07883; DNA-binding protein 1606146..1606682 Escherichia coli E24377A 5589885 YP_001462707.1 CDS EcE24377A_1614 NC_009801.1 1606713 1608716 D identified by match to protein family HMM PF01136; U32 family peptidase 1606713..1608716 Escherichia coli E24377A 5588801 YP_001462708.1 CDS EcE24377A_1615 NC_009801.1 1608808 1609038 R hypothetical protein complement(1608808..1609038) Escherichia coli E24377A 5586122 YP_001462709.1 CDS EcE24377A_1616 NC_009801.1 1609095 1609217 R identified by similarity to GB:AAN80324.1; hypothetical protein complement(1609095..1609217) Escherichia coli E24377A 5590119 YP_001462710.1 CDS EcE24377A_1617 NC_009801.1 1609461 1609898 D identified by match to protein family HMM PF01381; match to protein family HMM PF03681; DNA-binding protein 1609461..1609898 Escherichia coli E24377A 5589459 YP_001462711.1 CDS EcE24377A_1618 NC_009801.1 1609977 1611383 D identified by match to protein family HMM PF00155; match to protein family HMM PF00392; GntR family transcriptional regulator 1609977..1611383 Escherichia coli E24377A 5588121 YP_001462712.1 CDS ydcS NC_009801.1 1611628 1612773 D identified by match to protein family HMM PF01547; ABC transporter periplasmic substrate-binding protein 1611628..1612773 Escherichia coli E24377A 5587215 YP_001462713.1 CDS ydcT NC_009801.1 1612791 1613804 D identified by match to protein family HMM PF00005; match to protein family HMM PF08402; ABC transporter ATP-binding protein 1612791..1613804 Escherichia coli E24377A 5586704 YP_001462714.1 CDS ydcU NC_009801.1 1613805 1614746 D identified by match to protein family HMM PF00528; ABC transporter permease 1613805..1614746 Escherichia coli E24377A 5589507 YP_001462715.1 CDS ydcV NC_009801.1 1614736 1615530 D identified by match to protein family HMM PF00528; ABC transporter permease 1614736..1615530 Escherichia coli E24377A 5587995 YP_001462716.1 CDS ydcW NC_009801.1 1615552 1616976 D catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1615552..1616976 Escherichia coli E24377A 5586995 YP_001462717.1 CDS EcE24377A_1623 NC_009801.1 1616973 1617089 R identified by glimmer; hypothetical protein complement(1616973..1617089) Escherichia coli E24377A 5586489 YP_001462718.1 CDS EcE24377A_1625 NC_009801.1 1617288 1617536 D hypothetical protein 1617288..1617536 Escherichia coli E24377A 5590113 YP_001462719.1 CDS EcE24377A_1626 NC_009801.1 1617491 1617595 D identified by glimmer; hypothetical protein 1617491..1617595 Escherichia coli E24377A 5590637 YP_001462720.1 CDS EcE24377A_1627 NC_009801.1 1617622 1617855 D hypothetical protein 1617622..1617855 Escherichia coli E24377A 5589828 YP_001462721.1 CDS EcE24377A_1628 NC_009801.1 1617856 1618305 R identified by match to protein family HMM PF04657; hypothetical protein complement(1617856..1618305) Escherichia coli E24377A 5588665 YP_001462722.1 CDS EcE24377A_1629 NC_009801.1 1618302 1618883 R identified by match to protein family HMM PF00583; acetyltransferase complement(1618302..1618883) Escherichia coli E24377A 5588104 YP_001462723.1 CDS EcE24377A_1630 NC_009801.1 1619001 1620038 D identified by match to protein family HMM PF00107; zinc-binding dehydrogenase oxidoreductase 1619001..1620038 Escherichia coli E24377A 5586959 YP_001462724.1 CDS EcE24377A_1631 NC_009801.1 1620236 1620901 D identified by match to protein family HMM PF00392; match to protein family HMM PF07729; DNA-binding transcriptional regulator 1620236..1620901 Escherichia coli E24377A 5587654 YP_001462725.1 CDS EcE24377A_1632 NC_009801.1 1620937 1623039 R identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR03304; TonB-dependent receptor complement(1620937..1623039) Escherichia coli E24377A 5590138 YP_001462726.1 CDS EcE24377A_1633 NC_009801.1 1623038 1623133 D identified by glimmer; hypothetical protein 1623038..1623133 Escherichia coli E24377A 5588549 YP_001462727.1 CDS EcE24377A_1634 NC_009801.1 1623281 1624342 D hypothetical protein 1623281..1624342 Escherichia coli E24377A 5586535 YP_001462728.1 CDS ansP NC_009801.1 1624457 1625956 R identified by match to protein family HMM PF00324; L-asparagine permease complement(1624457..1625956) Escherichia coli E24377A 5587724 YP_001462729.1 CDS EcE24377A_1637 NC_009801.1 1627539 1627685 R identified by glimmer; hypothetical protein complement(1627539..1627685) Escherichia coli E24377A 5587118 YP_001462730.1 CDS EcE24377A_1638 NC_009801.1 1627947 1630055 D identified by match to protein family HMM PF04524; match to protein family HMM PF06715; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361; ImpA family type VI secretion-associated protein 1627947..1630055 Escherichia coli E24377A 5587871 YP_001462731.1 CDS EcE24377A_1639 NC_009801.1 1630123 1634340 D identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; protein rhsD, truncation 1630123..1634340 Escherichia coli E24377A 5587433 YP_001462732.1 CDS EcE24377A_1640 NC_009801.1 1634537 1634746 D identified by glimmer; hypothetical protein 1634537..1634746 Escherichia coli E24377A 5585903 YP_001462733.1 CDS EcE24377A_1642 NC_009801.1 1636489 1636716 D 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1636489..1636716 Escherichia coli E24377A 5586827 YP_001462734.1 CDS EcE24377A_1643 NC_009801.1 1636720 1637289 R identified by match to protein family HMM PF01613; flavin reductase domain-containing protein complement(1636720..1637289) Escherichia coli E24377A 5586659 YP_001462735.1 CDS EcE24377A_1644 NC_009801.1 1637462 1638307 D identified by match to protein family HMM PF00797; N-hydroxyarylamine O-acetyltransferase 1637462..1638307 Escherichia coli E24377A 5588460 YP_001462736.1 CDS EcE24377A_1645 NC_009801.1 1638403 1639296 R identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654; hypothetical protein complement(1638403..1639296) Escherichia coli E24377A 5586420 YP_001462737.1 CDS narI2 NC_009801.1 1639375 1640055 R identified by similarity to SP:P11350; match to protein family HMM PF02665; match to protein family HMM TIGR00351; respiratory nitrate reductase subunit gamma complement(1639375..1640055) Escherichia coli E24377A 5588201 YP_001462738.1 CDS narW NC_009801.1 1640052 1640747 R identified by similarity to SP:P19317; match to protein family HMM PF02613; match to protein family HMM TIGR00684; respiratory nitrate reductase 2 delta chain complement(1640052..1640747) Escherichia coli E24377A 5586699 YP_001462739.1 CDS narY NC_009801.1 1640747 1642291 R identified by similarity to SP:P19318; match to protein family HMM TIGR01660; nitrate reductase subunit beta complement(1640747..1642291) Escherichia coli E24377A 5590751 YP_001462740.1 CDS narZ NC_009801.1 1642257 1646027 R identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; nitrate reductase subunit alpha complement(1642257..1646027) Escherichia coli E24377A 5588831 YP_001462741.1 CDS narU NC_009801.1 1646109 1647497 R identified by similarity to SP:P37758; match to protein family HMM PF07690; match to protein family HMM TIGR00886; nitrite extrusion protein 2 complement(1646109..1647497) Escherichia coli E24377A 5587193 YP_001462742.1 CDS EcE24377A_1651 NC_009801.1 1647821 1649152 R identified by similarity to SP:P76123; hypothetical protein complement(1647821..1649152) Escherichia coli E24377A 5589263 YP_001462743.1 CDS EcE24377A_1652 NC_009801.1 1649176 1649466 R outer membrane porin, truncation complement(1649176..1649466) Escherichia coli E24377A 5589186 YP_001462744.1 CDS EcE24377A_1653 NC_009801.1 1649725 1650606 R identified by match to protein family HMM PF00892; hypothetical protein complement(1649725..1650606) Escherichia coli E24377A 5588296 YP_001462745.1 CDS fdnG NC_009801.1 1651474 1653885 D identified by similarity to SP:P24183; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01553; formate dehydrogenase, nitrate inducible subunit alpha, selenocysteine-containing 1651474..1653885 Escherichia coli E24377A 5588880 YP_001462746.1 CDS fdnH NC_009801.1 1653898 1654782 D identified by similarity to SP:P0AAJ3; match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582; formate dehydrogenase, nitrate-inducible, iron-sulfur subunit 1653898..1654782 Escherichia coli E24377A 5587328 YP_001462747.1 CDS fdnI NC_009801.1 1654757 1655428 D nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1654757..1655428 Escherichia coli E24377A 5587918 YP_001462748.1 CDS EcE24377A_1659 NC_009801.1 1655479 1655763 R identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607; addiction module antidote protein complement(1655479..1655763) Escherichia coli E24377A 5588616 YP_001462749.1 CDS EcE24377A_1660 NC_009801.1 1655910 1656920 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(1655910..1656920) Escherichia coli E24377A 5588501 YP_001462750.1 CDS sfcA NC_009801.1 1657054 1658751 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(1657054..1658751) Escherichia coli E24377A 5587318 YP_001462751.1 CDS rpsV NC_009801.1 1658908 1659045 R protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 complement(1658908..1659045) Escherichia coli E24377A 5587371 YP_001462752.1 CDS EcE24377A_1663 NC_009801.1 1659147 1659362 R identified by similarity to SP:P76127; biofilm-dependent modulation protein complement(1659147..1659362) Escherichia coli E24377A 5589532 YP_001462753.1 CDS osmC NC_009801.1 1659708 1660139 D identified by match to protein family HMM PF02566; peroxiredoxin OsmC 1659708..1660139 Escherichia coli E24377A 5589201 YP_001462754.1 CDS bdhA NC_009801.1 1660174 1660944 R catalyzes the formation of acetoacetate from 3-hydroxybutyrate; 3-hydroxybutyrate dehydrogenase complement(1660174..1660944) Escherichia coli E24377A 5590661 YP_001462755.1 CDS EcE24377A_1666 NC_009801.1 1660956 1662347 R identified by match to protein family HMM PF03600; citrate transporter family protein complement(1660956..1662347) Escherichia coli E24377A 5587179 YP_001462756.1 CDS EcE24377A_1667 NC_009801.1 1662393 1663316 R identified by match to protein family HMM PF00725; match to protein family HMM PF02737; 3-hydroxyacyl-CoA dehydrogenase complement(1662393..1663316) Escherichia coli E24377A 5587349 YP_001462757.1 CDS EcE24377A_1668 NC_009801.1 1663306 1664511 R identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; acetyl-CoA acetyltransferase complement(1663306..1664511) Escherichia coli E24377A 5590305 YP_001462758.1 CDS EcE24377A_1669 NC_009801.1 1664521 1665177 R identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428; 3-oxoacid CoA-transferase subunit B complement(1664521..1665177) Escherichia coli E24377A 5587558 YP_001462759.1 CDS pcaI NC_009801.1 1665180 1665887 R identified by similarity to SP:Q01103; match to protein family HMM PF01144; match to protein family HMM TIGR02429; 3-oxoadipate CoA-transferase subunit A complement(1665180..1665887) Escherichia coli E24377A 5589796 YP_001462760.1 CDS EcE24377A_1671 NC_009801.1 1666029 1666919 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1666029..1666919 Escherichia coli E24377A 5586744 YP_001462761.1 CDS EcE24377A_1672 NC_009801.1 1666956 1667882 R identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; ABC transporter ATP-binding protein complement(1666956..1667882) Escherichia coli E24377A 5590719 YP_001462762.1 CDS EcE24377A_1673 NC_009801.1 1667875 1668861 R identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; ABC transporter ATP-binding protein complement(1667875..1668861) Escherichia coli E24377A 5587712 YP_001462763.1 CDS EcE24377A_1674 NC_009801.1 1668858 1669754 R identified by similarity to SP:P77463; match to protein family HMM PF00528; ATP-dependent peptide transporter membrane subunit complement(1668858..1669754) Escherichia coli E24377A 5587241 YP_001462764.1 CDS EcE24377A_1675 NC_009801.1 1669751 1670773 R identified by match to protein family HMM PF00528; ABC transporter permease complement(1669751..1670773) Escherichia coli E24377A 5590461 YP_001462765.1 CDS ddpX NC_009801.1 1672323 1672904 R catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis; D-alanyl-D-alanine dipeptidase complement(1672323..1672904) Escherichia coli E24377A 5588678 YP_001462766.1 CDS dos NC_009801.1 1673162 1675585 R heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase complement(1673162..1675585) Escherichia coli E24377A 5585945 YP_001462767.1 CDS EcE24377A_1679 NC_009801.1 1675586 1676968 R identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase complement(1675586..1676968) Escherichia coli E24377A 5586359 YP_001462768.1 CDS EcE24377A_1680 NC_009801.1 1677340 1678659 R identified by match to protein family HMM PF02638; lipoprotein complement(1677340..1678659) Escherichia coli E24377A 5586815 YP_001462769.1 CDS gadC NC_009801.1 1678790 1680325 R identified by match to protein family HMM PF00324; match to protein family HMM TIGR00910; glutamate:gamma aminobutyrate antiporter complement(1678790..1680325) Escherichia coli E24377A 5590643 YP_001462770.1 CDS gadB NC_009801.1 1680481 1681881 R identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; glutamate decarboxylase GadB complement(1680481..1681881) Escherichia coli E24377A 5586277 YP_001462771.1 CDS EcE24377A_1683 NC_009801.1 1682000 1682113 R identified by glimmer; hypothetical protein complement(1682000..1682113) Escherichia coli E24377A 5589975 YP_001462772.1 CDS pqqL NC_009801.1 1682243 1685026 R identified by match to protein family HMM PF00675; match to protein family HMM PF05193; M16B family peptidase complement(1682243..1685026) Escherichia coli E24377A 5588445 YP_001462773.1 CDS EcE24377A_1685 NC_009801.1 1685083 1687455 R identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR03304; TonB-dependent receptor complement(1685083..1687455) Escherichia coli E24377A 5588528 YP_001462774.1 CDS yddA NC_009801.1 1687493 1689178 R identified by match to protein family HMM PF00005; match to protein family HMM PF05992; inner membrane ABC transporter ATP-binding protein yddA complement(1687493..1689178) Escherichia coli E24377A 5589904 YP_001462775.1 CDS EcE24377A_1687 NC_009801.1 1689469 1690626 R ydeM; identified by match to protein family HMM PF04055; radical SAM domain-containing protein complement(1689469..1690626) Escherichia coli E24377A 5588058 YP_001462776.1 CDS EcE24377A_1689 NC_009801.1 1692762 1693523 R regulates the cellular response to acid resistance; transcriptional regulator YdeO complement(1692762..1693523) Escherichia coli E24377A 5589407 YP_001462777.1 CDS EcE24377A_1690 NC_009801.1 1694043 1696322 R in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase; oxidoreductase complement(1694043..1696322) Escherichia coli E24377A 5588253 YP_001462778.1 CDS EcE24377A_1691 NC_009801.1 1696656 1697570 R identified by similarity to SP:P08191; match to protein family HMM PF00419; match to protein family HMM PF09160; protein FimH-like protein complement(1696656..1697570) Escherichia coli E24377A 5589282 YP_001462779.1 CDS EcE24377A_1692 NC_009801.1 1697629 1698132 R identified by similarity to SP:P08190; match to protein family HMM PF00419; protein fimG-like protein complement(1697629..1698132) Escherichia coli E24377A 5588990 YP_001462780.1 CDS EcE24377A_1693 NC_009801.1 1698145 1698675 R identified by match to protein family HMM PF00419; fimbrial protein complement(1698145..1698675) Escherichia coli E24377A 5587312 YP_001462781.1 CDS EcE24377A_1695 NC_009801.1 1700466 1700915 R identified by match to protein family HMM PF00345; match to protein family HMM PF02753; periplasmic pilus chaperone family protein complement(1700466..1700915) Escherichia coli E24377A 5588907 YP_001462782.1 CDS EcE24377A_1696 NC_009801.1 1700865 1700966 D identified by glimmer; hypothetical protein 1700865..1700966 Escherichia coli E24377A 5588277 YP_001462783.1 CDS EcE24377A_1697 NC_009801.1 1701792 1701917 D identified by glimmer; hypothetical protein 1701792..1701917 Escherichia coli E24377A 5588615 YP_001462784.1 CDS EcE24377A_1698 NC_009801.1 1701981 1703201 R identified by match to protein family HMM PF00263; match to protein family HMM PF03958; type II/III secretion system protein complement(1701981..1703201) Escherichia coli E24377A 5590442 YP_001462785.1 CDS EcE24377A_1699 NC_009801.1 1703211 1704467 R identified by glimmer; hypothetical protein complement(1703211..1704467) Escherichia coli E24377A 5588696 YP_001462786.1 CDS EcE24377A_1700 NC_009801.1 1704475 1704669 R identified by glimmer; hypothetical protein complement(1704475..1704669) Escherichia coli E24377A 5586764 YP_001462787.1 CDS EcE24377A_1702 NC_009801.1 1704619 1704897 D identified by glimmer; hypothetical protein 1704619..1704897 Escherichia coli E24377A 5590229 YP_001462788.1 CDS EcE24377A_1701 NC_009801.1 1704837 1706165 R identified by glimmer; hypothetical protein complement(1704837..1706165) Escherichia coli E24377A 5586306 YP_001462789.1 CDS EcE24377A_1703 NC_009801.1 1706221 1706496 R identified by glimmer; hypothetical protein complement(1706221..1706496) Escherichia coli E24377A 5587182 YP_001462790.1 CDS EcE24377A_1704 NC_009801.1 1706790 1707125 R identified by glimmer; hypothetical protein complement(1706790..1707125) Escherichia coli E24377A 5590431 YP_001462791.1 CDS EcE24377A_1705 NC_009801.1 1707135 1708331 R identified by match to protein family HMM PF02486; replication initiation factor family protein complement(1707135..1708331) Escherichia coli E24377A 5587019 YP_001462792.1 CDS EcE24377A_1706 NC_009801.1 1708331 1708528 R identified by glimmer; hypothetical protein complement(1708331..1708528) Escherichia coli E24377A 5586006 YP_001462793.1 CDS EcE24377A_1707 NC_009801.1 1708663 1708878 D identified by glimmer; hypothetical protein 1708663..1708878 Escherichia coli E24377A 5586232 YP_001462794.1 CDS EcE24377A_1708 NC_009801.1 1709205 1709369 R identified by glimmer; hypothetical protein complement(1709205..1709369) Escherichia coli E24377A 5588371 YP_001462795.1 CDS hipB NC_009801.1 1709802 1710086 R identified by similarity to SP:P23873; match to protein family HMM PF01381; DNA-binding transcriptional regulator HipB complement(1709802..1710086) Escherichia coli E24377A 5586312 YP_001462796.1 CDS EcE24377A_1710 NC_009801.1 1710157 1710249 R identified by glimmer; hypothetical protein complement(1710157..1710249) Escherichia coli E24377A 5590177 YP_001462797.1 CDS EcE24377A_1711 NC_009801.1 1710277 1714260 R identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR03304; outer membrane autotransporter domain-containing protein complement(1710277..1714260) Escherichia coli E24377A 5589960 YP_001462798.1 CDS lsrK NC_009801.1 1714791 1716383 R identified by similarity to SP:P77432; match to protein family HMM PF00370; match to protein family HMM PF02782; autoinducer-2 (AI-2) kinase complement(1714791..1716383) Escherichia coli E24377A 5586283 YP_001462799.1 CDS lsrR NC_009801.1 1716462 1717415 R identified by similarity to SP:P76141; match to protein family HMM PF04198; transcriptional repressor LsrR complement(1716462..1717415) Escherichia coli E24377A 5588050 YP_001462800.1 CDS lsrA NC_009801.1 1717664 1718665 D identified by similarity to SP:P77257; match to protein family HMM PF00005; autoinducer-2 ABC transporter ATP-binding protein LsrA 1717664..1718665 Escherichia coli E24377A 5589425 YP_001462801.1 CDS EcE24377A_1715 NC_009801.1 1718662 1719006 D identified by similarity to SP:P0AFS1; autoinducer-2 ABC transporter permease LsrD, truncation 1718662..1719006 Escherichia coli E24377A 5589974 YP_001462802.1 CDS lsrB NC_009801.1 1719018 1720040 D identified by similarity to SP:P76142; autoinducer-2 ABC transporter periplasmic autoinducer-2-binding protein LsrB 1719018..1720040 Escherichia coli E24377A 5586185 YP_001462803.1 CDS lsrF NC_009801.1 1720067 1720942 D identified by similarity to SP:P76143; match to protein family HMM PF01791; aldolase 1720067..1720942 Escherichia coli E24377A 5587401 YP_001462804.1 CDS tam NC_009801.1 1721313 1722071 D catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1721313..1722071 Escherichia coli E24377A 5590488 YP_001462805.1 CDS EcE24377A_1720 NC_009801.1 1722075 1723040 R identified by match to protein family HMM PF05249; hypothetical protein complement(1722075..1723040) Escherichia coli E24377A 5586172 YP_001462806.1 CDS uxaB NC_009801.1 1723196 1724647 R catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase complement(1723196..1724647) Escherichia coli E24377A 5588308 YP_001462807.1 CDS EcE24377A_1722 NC_009801.1 1724874 1726292 R identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase complement(1724874..1726292) Escherichia coli E24377A 5587157 YP_001462808.1 CDS EcE24377A_1723 NC_009801.1 1726431 1726790 R identified by similarity to GB:ABB61754.1; hypothetical protein complement(1726431..1726790) Escherichia coli E24377A 5586339 YP_001462809.1 CDS glsA2 NC_009801.1 1726790 1727716 R catalyzes the formation of glutamate from glutamine; glutaminase complement(1726790..1727716) Escherichia coli E24377A 5586584 YP_001462810.1 CDS EcE24377A_1725 NC_009801.1 1727780 1729168 R in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase complement(1727780..1729168) Escherichia coli E24377A 5590139 YP_001462811.1 CDS EcE24377A_1726 NC_009801.1 1729269 1730150 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1729269..1730150 Escherichia coli E24377A 5588084 YP_001462812.1 CDS EcE24377A_1728 NC_009801.1 1731295 1731414 R identified by glimmer; hypothetical protein complement(1731295..1731414) Escherichia coli E24377A 5588022 YP_001462813.1 CDS sotB NC_009801.1 1731491 1732681 D identified by similarity to SP:Q9S3J9; match to protein family HMM PF07690; sugar efflux transporter 1731491..1732681 Escherichia coli E24377A 5587095 YP_001462814.1 CDS marC NC_009801.1 1732706 1733371 R protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC complement(1732706..1733371) Escherichia coli E24377A 5588186 YP_001462815.1 CDS marR NC_009801.1 1733583 1734017 D Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1733583..1734017 Escherichia coli E24377A 5588157 YP_001462816.1 CDS marA NC_009801.1 1734037 1734420 D transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1734037..1734420 Escherichia coli E24377A 5586320 YP_001462817.1 CDS marB NC_009801.1 1734452 1734670 D identified by similarity to SP:P31121; hypothetical protein 1734452..1734670 Escherichia coli E24377A 5586502 YP_001462818.1 CDS celA NC_009801.1 1734727 1736166 R converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase complement(1734727..1736166) Escherichia coli E24377A 5590659 YP_001462819.1 CDS EcE24377A_1736 NC_009801.1 1736191 1737864 R identified by similarity to SP:P26218; match to protein family HMM PF02264; glucoside specific outer membrane porin BglH-like protein complement(1736191..1737864) Escherichia coli E24377A 5587669 YP_001462820.1 CDS EcE24377A_1737 NC_009801.1 1737920 1738231 R identified by match to protein family HMM PF02255; PTS system lactose/cellobiose-specific family IIA subunit complement(1737920..1738231) Escherichia coli E24377A 5586327 YP_001462821.1 CDS EcE24377A_1738 NC_009801.1 1738259 1739572 R identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; PTS system lactose/cellobiose family transporter subunit IIC complement(1738259..1739572) Escherichia coli E24377A 5590718 YP_001462822.1 CDS EcE24377A_1739 NC_009801.1 1739696 1740007 R identified by match to protein family HMM PF02302; PTS system lactose/cellobiose family transporter subunit IIB complement(1739696..1740007) Escherichia coli E24377A 5590203 YP_001462823.1 CDS EcE24377A_1740 NC_009801.1 1740206 1740904 D identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 1740206..1740904 Escherichia coli E24377A 5586529 YP_001462824.1 CDS eamA NC_009801.1 1740949 1741848 R identified by match to protein family HMM PF00892; match to protein family HMM PF03151; O-acetylserine/cysteine export protein complement(1740949..1741848) Escherichia coli E24377A 5587266 YP_001462825.1 CDS ydeE NC_009801.1 1742043 1743230 D YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 1742043..1743230 Escherichia coli E24377A 5589248 YP_001462826.1 CDS EcE24377A_1743 NC_009801.1 1743357 1743452 D identified by similarity to GB:AAV77284.1; hypothetical protein 1743357..1743452 Escherichia coli E24377A 5586606 YP_001462827.1 CDS EcE24377A_1744 NC_009801.1 1743671 1744561 R identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; hypothetical protein complement(1743671..1744561) Escherichia coli E24377A 5589529 YP_001462828.1 CDS EcE24377A_1745 NC_009801.1 1744816 1745208 R identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156; hypothetical protein complement(1744816..1745208) Escherichia coli E24377A 5585927 YP_001462829.1 CDS EcE24377A_1746 NC_009801.1 1745484 1746002 D identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199; competence damage-inducible protein A 1745484..1746002 Escherichia coli E24377A 5590042 YP_001462830.1 CDS dcp NC_009801.1 1746047 1748092 R identified by similarity to SP:P24171; match to protein family HMM PF01432; dipeptidyl carboxypeptidase II complement(1746047..1748092) Escherichia coli E24377A 5587928 YP_001462831.1 CDS EcE24377A_1748 NC_009801.1 1748229 1748975 D NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1748229..1748975 Escherichia coli E24377A 5586454 YP_001462832.1 CDS EcE24377A_1749 NC_009801.1 1749064 1749750 D identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 1749064..1749750 Escherichia coli E24377A 5586424 YP_001462833.1 CDS EcE24377A_1750 NC_009801.1 1749928 1750131 D identified by similarity to SP:P64466; hypothetical protein 1749928..1750131 Escherichia coli E24377A 5589517 YP_001462834.1 CDS EcE24377A_1751 NC_009801.1 1750167 1751627 R identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol dehydrogenase complement(1750167..1751627) Escherichia coli E24377A 5586218 YP_001462835.1 CDS ydfJ NC_009801.1 1751716 1752999 R identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883; inner membrane metabolite transport protein ydfJ complement(1751716..1752999) Escherichia coli E24377A 5587644 YP_001462836.1 CDS EcE24377A_1753 NC_009801.1 1753753 1754019 D identified by similarity to SP:P76154; hypothetical protein 1753753..1754019 Escherichia coli E24377A 5588991 YP_001462837.1 CDS pinR NC_009801.1 1754336 1754926 D identified by match to protein family HMM PF00239; match to protein family HMM PF02796; site-specific recombinase resolvase PinR 1754336..1754926 Escherichia coli E24377A 5588206 YP_001462838.1 CDS EcE24377A_1755 NC_009801.1 1755024 1755599 R identified by similarity to SP:P03740; match to protein family HMM PF02413; tail fiber assembly protein complement(1755024..1755599) Escherichia coli E24377A 5589661 YP_001462839.1 CDS EcE24377A_1756 NC_009801.1 1756324 1756512 R hypothetical protein complement(1756324..1756512) Escherichia coli E24377A 5589165 YP_001462840.1 CDS EcE24377A_1757 NC_009801.1 1756610 1758181 R identified by match to protein family HMM PF03050; IS66 family transposase complement(1756610..1758181) Escherichia coli E24377A 5586366 YP_001462841.1 CDS EcE24377A_1758 NC_009801.1 1758201 1758548 R identified by match to protein family HMM PF05717; IS66 family orf2 complement(1758201..1758548) Escherichia coli E24377A 5586107 YP_001462842.1 CDS EcE24377A_1759 NC_009801.1 1758548 1759012 R identified by match to protein family HMM PF01527; IS66 family orf1 complement(1758548..1759012) Escherichia coli E24377A 5586658 YP_001462843.1 CDS EcE24377A_1760 NC_009801.1 1759035 1760573 R identified by match to protein family HMM PF03050; IS66 family transposase complement(1759035..1760573) Escherichia coli E24377A 5586328 YP_001462844.1 CDS EcE24377A_1761 NC_009801.1 1760623 1760970 R identified by match to protein family HMM PF05717; IS66 family orf2 complement(1760623..1760970) Escherichia coli E24377A 5588096 YP_001462845.1 CDS EcE24377A_1762 NC_009801.1 1760967 1761356 R identified by match to protein family HMM PF01527; IS66 family orf1 complement(1760967..1761356) Escherichia coli E24377A 5588364 YP_001462846.1 CDS EcE24377A_1763 NC_009801.1 1761395 1761637 R identified by match to protein family HMM PF04971; lysis protein S complement(1761395..1761637) Escherichia coli E24377A 5585912 YP_001462847.1 CDS EcE24377A_1764 NC_009801.1 1762011 1762142 R identified by glimmer; hypothetical protein complement(1762011..1762142) Escherichia coli E24377A 5588561 YP_001462848.1 CDS EcE24377A_1765 NC_009801.1 1762391 1762606 R identified by match to protein family HMM PF00313; cold shock DNA-binding protein complement(1762391..1762606) Escherichia coli E24377A 5589005 YP_001462849.1 CDS EcE24377A_1766 NC_009801.1 1763282 1764034 R identified by match to protein family HMM PF03589; antitermination protein complement(1763282..1764034) Escherichia coli E24377A 5587104 YP_001462850.1 CDS EcE24377A_1767 NC_009801.1 1764048 1765097 R identified by similarity to SP:P76162; match to protein family HMM PF06914; hypothetical protein complement(1764048..1765097) Escherichia coli E24377A 5588439 YP_001462851.1 CDS EcE24377A_1768 NC_009801.1 1765444 1765692 R hypothetical protein complement(1765444..1765692) Escherichia coli E24377A 5586093 YP_001462852.1 CDS EcE24377A_1770 NC_009801.1 1765757 1765873 R identified by glimmer; hypothetical protein complement(1765757..1765873) Escherichia coli E24377A 5587774 YP_001462853.1 CDS EcE24377A_1771 NC_009801.1 1766746 1768521 R hypothetical protein complement(1766746..1768521) Escherichia coli E24377A 5589591 YP_001462854.1 CDS EcE24377A_1772 NC_009801.1 1769148 1769447 D identified by match to protein family HMM PF01527; IS3, transposase orfA 1769148..1769447 Escherichia coli E24377A 5586310 YP_001462855.1 CDS EcE24377A_1774 NC_009801.1 1770339 1770530 R identified by match to protein family HMM PF06163; hypothetical protein complement(1770339..1770530) Escherichia coli E24377A 5587094 YP_001462856.1 CDS EcE24377A_1775 NC_009801.1 1770571 1771536 R identified by similarity to SP:P03688; phage O family protein complement(1770571..1771536) Escherichia coli E24377A 5588069 YP_001462857.1 CDS EcE24377A_1776 NC_009801.1 1771517 1772038 R identified by similarity to GB:BAB35190.1; match to protein family HMM PF06254; hypothetical protein complement(1771517..1772038) Escherichia coli E24377A 5588407 YP_001462858.1 CDS dicC NC_009801.1 1772022 1772252 R identified by similarity to SP:P06965; DNA-binding transcriptional regulator DicC complement(1772022..1772252) Escherichia coli E24377A 5589208 YP_001462859.1 CDS EcE24377A_1778 NC_009801.1 1772711 1772803 R identified by glimmer; hypothetical protein complement(1772711..1772803) Escherichia coli E24377A 5590739 YP_001462860.1 CDS EcE24377A_1779 NC_009801.1 1772910 1773065 D identified by match to protein family HMM PF07151; hypothetical protein 1772910..1773065 Escherichia coli E24377A 5587801 YP_001462861.1 CDS EcE24377A_1780 NC_009801.1 1773863 1774018 R identified by glimmer; hypothetical protein complement(1773863..1774018) Escherichia coli E24377A 5588340 YP_001462862.1 CDS dicB NC_009801.1 1774024 1774317 D identified by similarity to SP:P09557; match to protein family HMM PF05358; division inhibition protein DicB 1774024..1774317 Escherichia coli E24377A 5586183 YP_001462863.1 CDS EcE24377A_1782 NC_009801.1 1774314 1774505 D identified by match to protein family HMM PF07358; hypothetical protein 1774314..1774505 Escherichia coli E24377A 5588335 YP_001462864.1 CDS EcE24377A_1784 NC_009801.1 1774599 1777076 D identified by match to protein family HMM PF00929; exonuclease 1774599..1777076 Escherichia coli E24377A 5590263 YP_001462865.1 CDS EcE24377A_1783 NC_009801.1 1777073 1777165 R identified by glimmer; hypothetical protein complement(1777073..1777165) Escherichia coli E24377A 5589122 YP_001462866.1 CDS EcE24377A_1785 NC_009801.1 1777149 1777400 D identified by match to protein family HMM PF06806; phage excisionase 1777149..1777400 Escherichia coli E24377A 5587329 YP_001462867.1 CDS EcE24377A_1786 NC_009801.1 1777435 1778715 D identified by match to protein family HMM PF00589; phage integrase site specific recombinase 1777435..1778715 Escherichia coli E24377A 5586343 YP_001462868.1 CDS rspB NC_009801.1 1778903 1779922 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; dehydrogenase complement(1778903..1779922) Escherichia coli E24377A 5588272 YP_001462869.1 CDS rspA1 NC_009801.1 1779934 1781148 R identified by similarity to SP:P38104; match to protein family HMM PF01188; match to protein family HMM PF02746; starvation-sensing protein RspA complement(1779934..1781148) Escherichia coli E24377A 5585915 YP_001462870.1 CDS EcE24377A_1789 NC_009801.1 1781354 1781680 R identified by match to protein family HMM PF02694; hypothetical protein complement(1781354..1781680) Escherichia coli E24377A 5589863 YP_001462871.1 CDS EcE24377A_1790 NC_009801.1 1781815 1782156 D identified by match to protein family HMM PF06932; hypothetical protein 1781815..1782156 Escherichia coli E24377A 5590144 YP_001462872.1 CDS speG NC_009801.1 1782191 1782751 D identified by similarity to SP:P0A951; match to protein family HMM PF00583; diamine N-acetyltransferase 1782191..1782751 Escherichia coli E24377A 5588524 YP_001462873.1 CDS EcE24377A_1792 NC_009801.1 1782754 1783500 R identified by match to protein family HMM PF06788; hypothetical protein complement(1782754..1783500) Escherichia coli E24377A 5590094 YP_001462874.1 CDS EcE24377A_1793 NC_009801.1 1783572 1783877 D identified by match to protein family HMM PF06649; hypothetical protein 1783572..1783877 Escherichia coli E24377A 5589402 YP_001462875.1 CDS ynfE NC_009801.1 1784076 1786502 D identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166; anaerobic dimethyl sulfoxide reductase, A subunit YnfE 1784076..1786502 Escherichia coli E24377A 5586527 YP_001462876.1 CDS EcE24377A_1795 NC_009801.1 1786563 1788986 D identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166; anaerobic dimethyl sulfoxide reductase subunit A 1786563..1788986 Escherichia coli E24377A 5588067 YP_001462877.1 CDS dmsB2 NC_009801.1 1788997 1789614 D identified by similarity to SP:P18776; match to protein family HMM PF00037; match to protein family HMM TIGR02951; dimethylsulfoxide reductase subunit B 1788997..1789614 Escherichia coli E24377A 5587285 YP_001462878.1 CDS dmsC2 NC_009801.1 1789616 1790470 D identified by match to protein family HMM PF04976; anaerobic dimethyl sulfoxide reductase subunit C 1789616..1790470 Escherichia coli E24377A 5587682 YP_001462879.1 CDS dmsD NC_009801.1 1790513 1791127 D binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1790513..1791127 Escherichia coli E24377A 5589801 YP_001462880.1 CDS EcE24377A_1800 NC_009801.1 1791323 1792579 D identified by match to protein family HMM PF00654; voltage-gated ClC-type chloride channel ClcB 1791323..1792579 Escherichia coli E24377A 5589110 YP_001462881.1 CDS EcE24377A_1799 NC_009801.1 1792532 1793227 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(1792532..1793227) Escherichia coli E24377A 5590592 YP_001462882.1 CDS mic NC_009801.1 1793352 1794572 R identified by similarity to SP:P50456; match to protein family HMM PF00480; transcriptional regulator Mic complement(1793352..1794572) Escherichia coli E24377A 5589327 YP_001462883.1 CDS EcE24377A_1802 NC_009801.1 1794707 1795600 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(1794707..1795600) Escherichia coli E24377A 5586990 YP_001462884.1 CDS ynfM NC_009801.1 1795707 1796960 D identified by match to protein family HMM PF07690; major facilitator family transporter 1795707..1796960 Escherichia coli E24377A 5589626 YP_001462885.1 CDS EcE24377A_1804 NC_009801.1 1797357 1797692 D required for growth and survival under moderately acid conditions; acid shock protein 1797357..1797692 Escherichia coli E24377A 5590881 YP_001462886.1 CDS EcE24377A_1805 NC_009801.1 1797968 1798789 D identified by match to protein family HMM PF00089; S1A family peptidase 1797968..1798789 Escherichia coli E24377A 5590726 YP_001462887.1 CDS mdtI NC_009801.1 1798828 1799157 R with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI complement(1798828..1799157) Escherichia coli E24377A 5589814 YP_001462888.1 CDS mdtJ NC_009801.1 1799144 1799509 R with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ complement(1799144..1799509) Escherichia coli E24377A 5586220 YP_001462889.1 CDS tqsA NC_009801.1 1799921 1800955 D transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transporter 1799921..1800955 Escherichia coli E24377A 5586790 YP_001462890.1 CDS pntB NC_009801.1 1800980 1802368 R catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(1800980..1802368) Escherichia coli E24377A 5586855 YP_001462891.1 CDS pntA NC_009801.1 1802379 1803911 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(1802379..1803911) Escherichia coli E24377A 5589805 YP_001462892.1 CDS EcE24377A_1811 NC_009801.1 1804335 1804445 D identified by glimmer; hypothetical protein 1804335..1804445 Escherichia coli E24377A 5589002 YP_001462893.1 CDS ydgH NC_009801.1 1804435 1805379 D identified by match to protein family HMM PF07338; hypothetical protein 1804435..1805379 Escherichia coli E24377A 5586907 YP_001462894.1 CDS arcD NC_009801.1 1805565 1806947 D identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905; arginine/ornithine antiporter 1805565..1806947 Escherichia coli E24377A 5587839 YP_001462895.1 CDS EcE24377A_1815 NC_009801.1 1806984 1807706 D identified by match to protein family HMM PF00106; short chain dehydrogenase 1806984..1807706 Escherichia coli E24377A 5588797 YP_001462896.1 CDS EcE24377A_1814 NC_009801.1 1807703 1808038 R identified by match to protein family HMM PF06942; hypothetical protein complement(1807703..1808038) Escherichia coli E24377A 5587027 YP_001462897.1 CDS rstA NC_009801.1 1808167 1808886 D response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1808167..1808886 Escherichia coli E24377A 5589864 YP_001462898.1 CDS rstB NC_009801.1 1808890 1810191 D identified by similarity to SP:P18392; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor protein RstB 1808890..1810191 Escherichia coli E24377A 5586209 YP_001462899.1 CDS tus NC_009801.1 1810267 1811196 D binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1810267..1811196 Escherichia coli E24377A 5590049 YP_001462900.1 CDS fumC NC_009801.1 1811193 1812596 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1811193..1812596) Escherichia coli E24377A 5586726 YP_001462901.1 CDS fumA NC_009801.1 1812738 1814384 R identified by similarity to SP:P0AC33; match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723; fumarate hydratase complement(1812738..1814384) Escherichia coli E24377A 5588885 YP_001462902.1 CDS manA NC_009801.1 1814583 1815758 D identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218; mannose-6-phosphate isomerase 1814583..1815758 Escherichia coli E24377A 5587221 YP_001462903.1 CDS EcE24377A_1822 NC_009801.1 1815859 1817367 D identified by match to protein family HMM PF06097; hypothetical protein 1815859..1817367 Escherichia coli E24377A 5588054 YP_001462904.1 CDS uidC NC_009801.1 1817412 1818677 R identified by similarity to SP:Q47706; match to protein family HMM PF03573; outer membrane porin protein complement(1817412..1818677) Escherichia coli E24377A 5586944 YP_001462905.1 CDS uidB NC_009801.1 1818716 1820089 R identified by similarity to SP:P30868; match to protein family HMM PF07690; match to protein family HMM TIGR00792; glucuronide transporter complement(1818716..1820089) Escherichia coli E24377A 5585913 YP_001462906.1 CDS uidA NC_009801.1 1820086 1821897 R identified by similarity to SP:P05804; match to protein family HMM PF00703; match to protein family HMM PF02836; match to protein family HMM PF02837; beta-D-glucuronidase complement(1820086..1821897) Escherichia coli E24377A 5590771 YP_001462907.1 CDS uidR NC_009801.1 1822286 1822876 R identified by match to protein family HMM PF00440; transcriptional regulator UidR complement(1822286..1822876) Escherichia coli E24377A 5588133 YP_001462908.1 CDS EcE24377A_1827 NC_009801.1 1823105 1823872 R Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase complement(1823105..1823872) Escherichia coli E24377A 5585929 YP_001462909.1 CDS malI NC_009801.1 1823984 1825012 R regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI complement(1823984..1825012) Escherichia coli E24377A 5590226 YP_001462910.1 CDS malX NC_009801.1 1825187 1826779 D phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1825187..1826779 Escherichia coli E24377A 5586215 YP_001462911.1 CDS malY NC_009801.1 1826789 1827961 D identified by similarity to SP:P23256; match to protein family HMM PF00155; MalY protein 1826789..1827961 Escherichia coli E24377A 5590046 YP_001462912.1 CDS add NC_009801.1 1828065 1829066 D catalyzes the formation of inosine from adenosine; adenosine deaminase 1828065..1829066 Escherichia coli E24377A 5587676 YP_001462913.1 CDS EcE24377A_1832 NC_009801.1 1829101 1830180 R identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase complement(1829101..1830180) Escherichia coli E24377A 5589358 YP_001462914.1 CDS EcE24377A_1833 NC_009801.1 1830782 1830997 D YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1830782..1830997 Escherichia coli E24377A 5590856 YP_001462915.1 CDS EcE24377A_1834 NC_009801.1 1831083 1831523 D hypothetical protein 1831083..1831523 Escherichia coli E24377A 5587976 YP_001462916.1 CDS rnfA NC_009801.1 1831600 1832181 D identified by match to protein family HMM PF02508; match to protein family HMM TIGR01943; Na(+)-translocating NADH-quinone reductase subunit E 1831600..1832181 Escherichia coli E24377A 5588750 YP_001462917.1 CDS rnfB NC_009801.1 1832181 1832759 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1832181..1832759 Escherichia coli E24377A 5590664 YP_001462918.1 CDS rnfC NC_009801.1 1832752 1834974 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1832752..1834974 Escherichia coli E24377A 5586392 YP_001462919.1 CDS rnfD NC_009801.1 1834975 1836033 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1834975..1836033 Escherichia coli E24377A 5589332 YP_001462920.1 CDS rnfG NC_009801.1 1836037 1836657 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1836037..1836657 Escherichia coli E24377A 5586480 YP_001462921.1 CDS rnfE NC_009801.1 1836661 1837356 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 1836661..1837356 Escherichia coli E24377A 5590687 YP_001462922.1 CDS EcE24377A_1840 NC_009801.1 1836945 1837655 R identified by glimmer; hypothetical protein complement(1836945..1837655) Escherichia coli E24377A 5587487 YP_001462923.1 CDS nth NC_009801.1 1837356 1837991 D DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1837356..1837991 Escherichia coli E24377A 5586027 YP_001462924.1 CDS EcE24377A_1843 NC_009801.1 1838545 1838655 R identified by glimmer; hypothetical protein complement(1838545..1838655) Escherichia coli E24377A 5589541 YP_001462925.1 CDS tppB NC_009801.1 1838603 1840105 D mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 1838603..1840105 Escherichia coli E24377A 5588859 YP_001462926.1 CDS EcE24377A_1845 NC_009801.1 1840211 1840816 D identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathionine S-transferase 1840211..1840816 Escherichia coli E24377A 5587772 YP_001462927.1 CDS pdxY NC_009801.1 1840860 1841720 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(1840860..1841720) Escherichia coli E24377A 5589515 YP_001462928.1 CDS tyrS NC_009801.1 1841782 1843056 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(1841782..1843056) Escherichia coli E24377A 5590347 YP_001462929.1 CDS pdxH NC_009801.1 1843185 1843841 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(1843185..1843841) Escherichia coli E24377A 5587953 YP_001462930.1 CDS EcE24377A_1849 NC_009801.1 1843900 1844223 R MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor complement(1843900..1844223) Escherichia coli E24377A 5589641 YP_001462931.1 CDS anmK NC_009801.1 1844327 1845436 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(1844327..1845436) Escherichia coli E24377A 5587775 YP_001462932.1 CDS slyB NC_009801.1 1845710 1846177 D identified by similarity to SP:P0A1X0; match to protein family HMM PF05433; outer membrane lipoprotein SlyB 1845710..1846177 Escherichia coli E24377A 5590698 YP_001462933.1 CDS EcE24377A_1852 NC_009801.1 1846224 1846658 R Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA complement(1846224..1846658) Escherichia coli E24377A 5586230 YP_001462934.1 CDS EcE24377A_1853 NC_009801.1 1846683 1846802 R identified by glimmer; hypothetical protein complement(1846683..1846802) Escherichia coli E24377A 5587578 YP_001462935.1 CDS EcE24377A_1854 NC_009801.1 1846859 1847095 D identified by match to protein family HMM PF07869; hypothetical protein 1846859..1847095 Escherichia coli E24377A 5586417 YP_001462936.1 CDS EcE24377A_1855 NC_009801.1 1847098 1847955 D identified by match to protein family HMM PF00529; MFP family transporter 1847098..1847955 Escherichia coli E24377A 5590450 YP_001462937.1 CDS EcE24377A_1856 NC_009801.1 1847955 1849967 D identified by match to protein family HMM PF04632; fusaric acid resistance domain-containing protein 1847955..1849967 Escherichia coli E24377A 5589049 YP_001462938.1 CDS sodC NC_009801.1 1849968 1850489 R SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase complement(1849968..1850489) Escherichia coli E24377A 5588209 YP_001462939.1 CDS ydhF NC_009801.1 1850570 1851466 R identified by similarity to SP:P76187; match to protein family HMM PF00248; oxidoreductase YdhF complement(1850570..1851466) Escherichia coli E24377A 5589772 YP_001462940.1 CDS EcE24377A_1859 NC_009801.1 1851526 1851645 D identified by glimmer; hypothetical protein 1851526..1851645 Escherichia coli E24377A 5589508 YP_001462941.1 CDS EcE24377A_1860 NC_009801.1 1851857 1852456 D identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1851857..1852456 Escherichia coli E24377A 5590472 YP_001462942.1 CDS nemA NC_009801.1 1852493 1853590 D FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1852493..1853590 Escherichia coli E24377A 5586694 YP_001462943.1 CDS gloA NC_009801.1 1853671 1854078 D Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1853671..1854078 Escherichia coli E24377A 5586412 YP_001462944.1 CDS rnt NC_009801.1 1854181 1854828 D Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1854181..1854828 Escherichia coli E24377A 5587438 YP_001462945.1 CDS EcE24377A_1864 NC_009801.1 1854859 1854969 R identified by glimmer; hypothetical protein complement(1854859..1854969) Escherichia coli E24377A 5588198 YP_001462946.1 CDS lhr NC_009801.1 1854921 1859537 D similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli; ATP-dependent helicase Lhr 1854921..1859537 Escherichia coli E24377A 5589921 YP_001462947.1 CDS EcE24377A_1866 NC_009801.1 1859588 1859935 R identified by similarity to SP:P0AC69; match to protein family HMM PF00462; match to protein family HMM TIGR00365; hypothetical protein complement(1859588..1859935) Escherichia coli E24377A 5586810 YP_001462948.1 CDS EcE24377A_1867 NC_009801.1 1860017 1860169 R identified by glimmer; hypothetical protein complement(1860017..1860169) Escherichia coli E24377A 5590757 YP_001462949.1 CDS EcE24377A_1868 NC_009801.1 1860269 1861084 D identified by match to protein family HMM PF00877; NlpC/P60 family protein 1860269..1861084 Escherichia coli E24377A 5589359 YP_001462950.1 CDS sodB NC_009801.1 1861212 1861793 D SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1861212..1861793 Escherichia coli E24377A 5586139 YP_001462951.1 CDS EcE24377A_1870 NC_009801.1 1861939 1863108 R identified by match to protein family HMM PF07690; major facilitator transporter complement(1861939..1863108) Escherichia coli E24377A 5590613 YP_001462952.1 CDS EcE24377A_1871 NC_009801.1 1863274 1863393 R identified by glimmer; membrane protein complement(1863274..1863393) Escherichia coli E24377A 5587218 YP_001462953.1 CDS purR NC_009801.1 1863662 1864687 D binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1863662..1864687 Escherichia coli E24377A 5585976 YP_001462954.1 CDS EcE24377A_1872 NC_009801.1 1864684 1865616 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator complement(1864684..1865616) Escherichia coli E24377A 5587628 YP_001462955.1 CDS ydhC NC_009801.1 1865729 1866940 D uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1865729..1866940 Escherichia coli E24377A 5587622 YP_001462956.1 CDS cfa NC_009801.1 1867231 1868379 D catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 1867231..1868379 Escherichia coli E24377A 5589234 YP_001462957.1 CDS ribE NC_009801.1 1868419 1869060 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(1868419..1869060) Escherichia coli E24377A 5590853 YP_001462958.1 CDS EcE24377A_1877 NC_009801.1 1869275 1870648 D NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1869275..1870648 Escherichia coli E24377A 5587923 YP_001462959.1 CDS EcE24377A_1878 NC_009801.1 1870689 1871945 R hypothetical protein complement(1870689..1871945) Escherichia coli E24377A 5587846 YP_001462960.1 CDS EcE24377A_1879 NC_009801.1 1872147 1872242 R identified by glimmer; hypothetical protein complement(1872147..1872242) Escherichia coli E24377A 5588314 YP_001462961.1 CDS EcE24377A_1882 NC_009801.1 1872518 1872823 D identified by similarity to GB:AAV79142.1; match to protein family HMM PF08803; hypothetical protein 1872518..1872823 Escherichia coli E24377A 5587516 YP_001462962.1 CDS EcE24377A_1884 NC_009801.1 1874565 1875377 R identified by similarity to GB:AAZ88190.1; hypothetical protein complement(1874565..1875377) Escherichia coli E24377A 5588463 YP_001462963.1 CDS EcE24377A_1885 NC_009801.1 1875381 1876166 R identified by match to protein family HMM PF01292; nickel-dependent hydrogenase, b-type cytochrome subunit complement(1875381..1876166) Escherichia coli E24377A 5590699 YP_001462964.1 CDS EcE24377A_1886 NC_009801.1 1876163 1876882 R identified by match to protein family HMM PF00037; (Fe-S)-binding protein complement(1876163..1876882) Escherichia coli E24377A 5589501 YP_001462965.1 CDS EcE24377A_1887 NC_009801.1 1876895 1877542 R identified by similarity to GB:AAZ88187.1; hypothetical protein complement(1876895..1877542) Escherichia coli E24377A 5587113 YP_001462966.1 CDS EcE24377A_1888 NC_009801.1 1877546 1879648 R identified by match to protein family HMM PF01314; match to protein family HMM PF02730; oxidoreductase complement(1877546..1879648) Escherichia coli E24377A 5589952 YP_001462967.1 CDS EcE24377A_1889 NC_009801.1 1879669 1880295 R identified by match to protein family HMM PF00037; hypothetical protein complement(1879669..1880295) Escherichia coli E24377A 5585906 YP_001462968.1 CDS EcE24377A_1890 NC_009801.1 1880323 1880460 D identified by glimmer; hypothetical protein 1880323..1880460 Escherichia coli E24377A 5589031 YP_001462969.1 CDS EcE24377A_1891 NC_009801.1 1880751 1880960 R hypothetical protein complement(1880751..1880960) Escherichia coli E24377A 5589977 YP_001462970.1 CDS pykF NC_009801.1 1881517 1882929 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1881517..1882929 Escherichia coli E24377A 5586596 YP_001462971.1 CDS lpp NC_009801.1 1883240 1883476 D identified by similarity to SP:P69776; match to protein family HMM PF04728; major outer membrane lipoprotein 1883240..1883476 Escherichia coli E24377A 5586507 YP_001462972.1 CDS EcE24377A_1894 NC_009801.1 1883540 1884544 R identified by match to protein family HMM PF01476; match to protein family HMM PF03734; LysM/ErfK/YbiS/YcfS/YnhG family protein complement(1883540..1884544) Escherichia coli E24377A 5589750 YP_001462973.1 CDS sufE NC_009801.1 1884693 1885109 R Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE complement(1884693..1885109) Escherichia coli E24377A 5588863 YP_001462974.1 CDS sufS NC_009801.1 1885122 1886342 R catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase complement(1885122..1886342) Escherichia coli E24377A 5586353 YP_001462975.1 CDS sufD NC_009801.1 1886339 1887610 R with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD complement(1886339..1887610) Escherichia coli E24377A 5589674 YP_001462976.1 CDS sufC NC_009801.1 1887585 1888331 R part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase complement(1887585..1888331) Escherichia coli E24377A 5590022 YP_001462977.1 CDS sufB NC_009801.1 1888341 1889828 R with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB complement(1888341..1889828) Escherichia coli E24377A 5586811 YP_001462978.1 CDS sufA NC_009801.1 1889837 1890205 R functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein complement(1889837..1890205) Escherichia coli E24377A 5589141 YP_001462979.1 CDS EcE24377A_1901 NC_009801.1 1890754 1891023 R identified by similarity to SP:P64478; hypothetical protein complement(1890754..1891023) Escherichia coli E24377A 5589849 YP_001462980.1 CDS ydiL NC_009801.1 1891042 1891452 R identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein complement(1891042..1891452) Escherichia coli E24377A 5589685 YP_001462981.1 CDS EcE24377A_1903 NC_009801.1 1891449 1894505 R identified by match to protein family HMM PF01565; match to protein family HMM PF02913; oxidoreductase, FAD-binding complement(1891449..1894505) Escherichia coli E24377A 5585985 YP_001462982.1 CDS ydiK NC_009801.1 1894894 1896006 D YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; inner membrane protein 1894894..1896006 Escherichia coli E24377A 5586419 YP_001462983.1 CDS EcE24377A_1905 NC_009801.1 1896408 1896791 D identified by similarity to GB:ABB61800.1; match to protein family HMM PF08965; hypothetical protein 1896408..1896791 Escherichia coli E24377A 5588153 YP_001462984.1 CDS ydiM NC_009801.1 1896891 1898105 D identified by match to protein family HMM PF07690; major facilitator family transporter 1896891..1898105 Escherichia coli E24377A 5588483 YP_001462985.1 CDS EcE24377A_1907 NC_009801.1 1898326 1899597 D identified by match to protein family HMM PF07690; major facilitator transporter 1898326..1899597 Escherichia coli E24377A 5588675 YP_001462986.1 CDS EcE24377A_1908 NC_009801.1 1899609 1900475 D YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 1899609..1900475 Escherichia coli E24377A 5589016 YP_001462987.1 CDS aroD NC_009801.1 1900506 1901264 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1900506..1901264 Escherichia coli E24377A 5586131 YP_001462988.1 CDS EcE24377A_1910 NC_009801.1 1901408 1903003 D identified by match to protein family HMM PF01144; CoA-transferase 1901408..1903003 Escherichia coli E24377A 5588146 YP_001462989.1 CDS EcE24377A_1911 NC_009801.1 1903017 1904168 D may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; acyl-CoA dehydrogenase 1903017..1904168 Escherichia coli E24377A 5586949 YP_001462990.1 CDS EcE24377A_1912 NC_009801.1 1904211 1905122 R identified by match to protein family HMM PF00165; match to protein family HMM PF02311; match to protein family HMM PF07883; AraC family transcriptional regulator complement(1904211..1905122) Escherichia coli E24377A 5589073 YP_001462991.1 CDS EcE24377A_1913 NC_009801.1 1905225 1905401 R identified by glimmer; hypothetical protein complement(1905225..1905401) Escherichia coli E24377A 5589699 YP_001462992.1 CDS fixA NC_009801.1 1905438 1906202 D YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; electron transfer flavoprotein YdiQ 1905438..1906202 Escherichia coli E24377A 5590770 YP_001462993.1 CDS EcE24377A_1915 NC_009801.1 1906222 1907160 D May play a role in a redox process; electron transfer flavoprotein subunit YdiR 1906222..1907160 Escherichia coli E24377A 5587144 YP_001462994.1 CDS EcE24377A_1916 NC_009801.1 1907216 1908505 D identified by similarity to SP:P68644; match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486; hypothetical protein 1907216..1908505 Escherichia coli E24377A 5586089 YP_001462995.1 CDS EcE24377A_1917 NC_009801.1 1908502 1908795 D (Fe-S)-binding protein 1908502..1908795 Escherichia coli E24377A 5590421 YP_001462996.1 CDS fadK NC_009801.1 1908852 1910498 D acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 1908852..1910498 Escherichia coli E24377A 5589217 YP_001462997.1 CDS ppsA NC_009801.1 1910555 1912933 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(1910555..1912933) Escherichia coli E24377A 5586962 YP_001462998.1 CDS EcE24377A_1920 NC_009801.1 1912987 1913154 R hypothetical protein complement(1912987..1913154) Escherichia coli E24377A 5586499 YP_001462999.1 CDS EcE24377A_1921 NC_009801.1 1913266 1914099 D identified by similarity to SP:Q8ZDY4; match to protein family HMM PF03618; hypothetical protein 1913266..1914099 Escherichia coli E24377A 5588803 YP_001463000.1 CDS aroH NC_009801.1 1914256 1915302 D tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1914256..1915302 Escherichia coli E24377A 5589175 YP_001463001.1 CDS EcE24377A_1923 NC_009801.1 1915434 1915625 D identified by similarity to GB:ABB66046.1; hypothetical protein 1915434..1915625 Escherichia coli E24377A 5586984 YP_001463002.1 CDS EcE24377A_1924 NC_009801.1 1915629 1917065 R identified by similarity to SP:Q8Z6I8; match to protein family HMM PF02696; hypothetical protein complement(1915629..1917065) Escherichia coli E24377A 5586545 YP_001463003.1 CDS EcE24377A_1925 NC_009801.1 1916156 1916257 D identified by glimmer; hypothetical protein 1916156..1916257 Escherichia coli E24377A 5589923 YP_001463004.1 CDS EcE24377A_1926 NC_009801.1 1917128 1917841 R identified by similarity to GB:AAP17004.1; hypothetical protein complement(1917128..1917841) Escherichia coli E24377A 5587136 YP_001463005.1 CDS EcE24377A_1927 NC_009801.1 1918088 1918552 R identified by match to protein family HMM PF00877; NlpC/P60 family lipoprotein complement(1918088..1918552) Escherichia coli E24377A 5588224 YP_001463006.1 CDS btuD NC_009801.1 1918630 1919379 R ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase complement(1918630..1919379) Escherichia coli E24377A 5590029 YP_001463007.1 CDS btuE NC_009801.1 1919379 1919930 R similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase complement(1919379..1919930) Escherichia coli E24377A 5590764 YP_001463008.1 CDS btuC NC_009801.1 1919993 1920973 R with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease complement(1919993..1920973) Escherichia coli E24377A 5588734 YP_001463009.1 CDS ihfA NC_009801.1 1921074 1921373 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha complement(1921074..1921373) Escherichia coli E24377A 5588033 YP_001463010.1 CDS pheT NC_009801.1 1921378 1923765 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(1921378..1923765) Escherichia coli E24377A 5586092 YP_001463011.1 CDS pheS NC_009801.1 1923780 1924763 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(1923780..1924763) Escherichia coli E24377A 5589852 YP_001463012.1 CDS EcE24377A_1934 NC_009801.1 1924877 1924972 R identified by glimmer; hypothetical protein complement(1924877..1924972) Escherichia coli E24377A 5586461 YP_001463013.1 CDS rplT NC_009801.1 1925214 1925570 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1925214..1925570) Escherichia coli E24377A 5588837 YP_001463014.1 CDS infC NC_009801.1 1925917 1926351 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(1925917..1926351) Escherichia coli E24377A 5589654 YP_001463015.1 CDS thrS NC_009801.1 1926463 1928391 R catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase complement(1926463..1928391) Escherichia coli E24377A 5586882 YP_001463016.1 CDS EcE24377A_1939 NC_009801.1 1930808 1930918 R identified by glimmer; hypothetical protein complement(1930808..1930918) Escherichia coli E24377A 5590653 YP_001463017.1 CDS EcE24377A_1941 NC_009801.1 1931149 1931907 R identified by match to protein family HMM PF04338; hypothetical protein complement(1931149..1931907) Escherichia coli E24377A 5587580 YP_001463018.1 CDS EcE24377A_1942 NC_009801.1 1932048 1932155 D identified by glimmer; hypothetical protein 1932048..1932155 Escherichia coli E24377A 5587620 YP_001463019.1 CDS pfkB NC_009801.1 1932194 1933123 D identified by similarity to SP:P06999; match to protein family HMM PF00294; match to protein family HMM TIGR03168; 6-phosphofructokinase 1932194..1933123 Escherichia coli E24377A 5586853 YP_001463020.1 CDS EcE24377A_1944 NC_009801.1 1933224 1933514 D identified by similarity to SP:P64479; hypothetical protein 1933224..1933514 Escherichia coli E24377A 5589101 YP_001463021.1 CDS EcE24377A_1945 NC_009801.1 1933620 1934480 D identified by match to protein family HMM PF01636; match to protein family HMM PF03881; fructosamine kinase 1933620..1934480 Escherichia coli E24377A 5587729 YP_001463022.1 CDS EcE24377A_1946 NC_009801.1 1934521 1935057 R identified by similarity to GB:AAZ88138.1; hypothetical protein complement(1934521..1935057) Escherichia coli E24377A 5586640 YP_001463023.1 CDS EcE24377A_1947 NC_009801.1 1935204 1935872 D YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1935204..1935872 Escherichia coli E24377A 5588652 YP_001463024.1 CDS EcE24377A_1949 NC_009801.1 1936035 1936625 D identified by match to protein family HMM PF04307; hypothetical protein 1936035..1936625 Escherichia coli E24377A 5586305 YP_001463025.1 CDS EcE24377A_1948 NC_009801.1 1936557 1936685 R identified by glimmer; hypothetical protein complement(1936557..1936685) Escherichia coli E24377A 5589390 YP_001463026.1 CDS EcE24377A_1950 NC_009801.1 1936758 1938149 D identified by match to protein family HMM PF00375; sodium/dicarboxylate symporter family protein 1936758..1938149 Escherichia coli E24377A 5588679 YP_001463027.1 CDS cedA NC_009801.1 1939245 1939487 R identified by similarity to SP:P0AE60; cell division modulator complement(1939245..1939487) Escherichia coli E24377A 5588112 YP_001463028.1 CDS katE NC_009801.1 1939691 1941952 D Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1939691..1941952 Escherichia coli E24377A 5589054 YP_001463029.1 CDS EcE24377A_1954 NC_009801.1 1941999 1942757 R identified by similarity to GB:BAB92994.1; match to protein family HMM PF04794; hypothetical protein complement(1941999..1942757) Escherichia coli E24377A 5590842 YP_001463030.1 CDS chbF NC_009801.1 1942770 1944122 R identified by similarity to SP:P17411; match to protein family HMM PF02056; 6-phospho-beta-glucosidase complement(1942770..1944122) Escherichia coli E24377A 5587016 YP_001463031.1 CDS chbR NC_009801.1 1944227 1945066 R represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR complement(1944227..1945066) Escherichia coli E24377A 5590132 YP_001463032.1 CDS chbA NC_009801.1 1945077 1945427 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA complement(1945077..1945427) Escherichia coli E24377A 5588727 YP_001463033.1 CDS chbC NC_009801.1 1945478 1946836 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC complement(1945478..1946836) Escherichia coli E24377A 5590299 YP_001463034.1 CDS chbB NC_009801.1 1946921 1947241 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB complement(1946921..1947241) Escherichia coli E24377A 5588927 YP_001463035.1 CDS osmE NC_009801.1 1947540 1947878 R osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE complement(1947540..1947878) Escherichia coli E24377A 5590313 YP_001463036.1 CDS nadE NC_009801.1 1948080 1948907 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1948080..1948907 Escherichia coli E24377A 5586821 YP_001463037.1 CDS cho NC_009801.1 1949137 1950024 D 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1949137..1950024 Escherichia coli E24377A 5590367 YP_001463038.1 CDS EcE24377A_1962 NC_009801.1 1949984 1950559 R identified by match to protein family HMM PF05962; hypothetical protein complement(1949984..1950559) Escherichia coli E24377A 5589663 YP_001463039.1 CDS spy NC_009801.1 1950762 1951247 R periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein complement(1950762..1951247) Escherichia coli E24377A 5590728 YP_001463040.1 CDS EcE24377A_1965 NC_009801.1 1951382 1951483 D identified by glimmer; hypothetical protein 1951382..1951483 Escherichia coli E24377A 5587799 YP_001463041.1 CDS astE NC_009801.1 1951577 1952545 R catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase complement(1951577..1952545) Escherichia coli E24377A 5586813 YP_001463042.1 CDS astB NC_009801.1 1952538 1953881 R catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase complement(1952538..1953881) Escherichia coli E24377A 5585946 YP_001463043.1 CDS astD NC_009801.1 1953878 1955356 R a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase complement(1953878..1955356) Escherichia coli E24377A 5586005 YP_001463044.1 CDS astA NC_009801.1 1955353 1956387 R identified by match to protein family HMM PF04958; match to protein family HMM TIGR03244; arginine succinyltransferase complement(1955353..1956387) Escherichia coli E24377A 5587085 YP_001463045.1 CDS astC NC_009801.1 1956384 1957604 R catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase complement(1956384..1957604) Escherichia coli E24377A 5588995 YP_001463046.1 CDS EcE24377A_1971 NC_009801.1 1957867 1958037 D identified by glimmer; hypothetical protein 1957867..1958037 Escherichia coli E24377A 5588979 YP_001463047.1 CDS xth NC_009801.1 1958050 1958856 D removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1958050..1958856 Escherichia coli E24377A 5586922 YP_001463048.1 CDS EcE24377A_1973 NC_009801.1 1959023 1959733 D identified by match to protein family HMM PF09335; hypothetical protein 1959023..1959733 Escherichia coli E24377A 5589623 YP_001463049.1 CDS EcE24377A_1974 NC_009801.1 1959576 1960415 D identified by similarity to GB:AAZ88114.1; hypothetical protein 1959576..1960415 Escherichia coli E24377A 5586059 YP_001463050.1 CDS EcE24377A_1975 NC_009801.1 1960430 1961137 D identified by similarity to SP:P76221; match to protein family HMM PF09335; hypothetical protein 1960430..1961137 Escherichia coli E24377A 5588360 YP_001463051.1 CDS EcE24377A_1976 NC_009801.1 1961137 1961685 D identified by match to protein family HMM PF02627; carboxymuconolactone decarboxylase 1961137..1961685 Escherichia coli E24377A 5586582 YP_001463052.1 CDS EcE24377A_1977 NC_009801.1 1961695 1962861 D ABC transporter substrate-binding protein 1961695..1962861 Escherichia coli E24377A 5587655 YP_001463053.1 CDS ynjC NC_009801.1 1962834 1964369 D ABC transporter permease 1962834..1964369 Escherichia coli E24377A 5589887 YP_001463054.1 CDS EcE24377A_1979 NC_009801.1 1964369 1965022 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1964369..1965022 Escherichia coli E24377A 5590418 YP_001463055.1 CDS EcE24377A_1980 NC_009801.1 1965089 1966396 D rhodanese-like domain-containing protein 1965089..1966396 Escherichia coli E24377A 5586403 YP_001463056.1 CDS EcE24377A_1981 NC_009801.1 1966405 1967025 R identified by match to protein family HMM PF01066; CDP-alcohol phosphatidyltransferase complement(1966405..1967025) Escherichia coli E24377A 5588262 YP_001463057.1 CDS nudG NC_009801.1 1967112 1967519 D identified by similarity to SP:P77788; match to protein family HMM PF00293; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1967112..1967519 Escherichia coli E24377A 5589936 YP_001463058.1 CDS EcE24377A_1982 NC_009801.1 1967485 1967757 R identified by match to protein family HMM PF07383; hypothetical protein complement(1967485..1967757) Escherichia coli E24377A 5588961 YP_001463059.1 CDS gdhA NC_009801.1 1967993 1969336 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1967993..1969336 Escherichia coli E24377A 5589791 YP_001463060.1 CDS EcE24377A_1985 NC_009801.1 1969453 1970493 R identified by similarity to GB:AAN43058.1; hypothetical protein complement(1969453..1970493) Escherichia coli E24377A 5588043 YP_001463061.1 CDS topB NC_009801.1 1970621 1972582 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(1970621..1972582) Escherichia coli E24377A 5587755 YP_001463062.1 CDS selD NC_009801.1 1972587 1973630 R catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase complement(1972587..1973630) Escherichia coli E24377A 5590441 YP_001463063.1 CDS EcE24377A_1988 NC_009801.1 1973747 1974298 R identified by match to protein family HMM PF00881; hypothetical protein complement(1973747..1974298) Escherichia coli E24377A 5587471 YP_001463064.1 CDS EcE24377A_1989 NC_009801.1 1974352 1974516 D identified by glimmer; hypothetical protein 1974352..1974516 Escherichia coli E24377A 5586946 YP_001463065.1 CDS sppA NC_009801.1 1974459 1976315 D SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 1974459..1976315 Escherichia coli E24377A 5587437 YP_001463066.1 CDS ansA NC_009801.1 1976482 1977498 D converts asparagine to aspartate and ammonia; asparaginase 1976482..1977498 Escherichia coli E24377A 5590799 YP_001463067.1 CDS pncA NC_009801.1 1977509 1978150 D catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 1977509..1978150 Escherichia coli E24377A 5587829 YP_001463068.1 CDS ydjE NC_009801.1 1978243 1979601 R identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator family transporter complement(1978243..1979601) Escherichia coli E24377A 5588309 YP_001463069.1 CDS EcE24377A_1994 NC_009801.1 1979718 1980476 R identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; DeoR family transcriptional regulator complement(1979718..1980476) Escherichia coli E24377A 5587156 YP_001463070.1 CDS EcE24377A_1995 NC_009801.1 1980613 1981593 R identified by match to protein family HMM PF00248; aldo/keto reductase complement(1980613..1981593) Escherichia coli E24377A 5587350 YP_001463071.1 CDS EcE24377A_1996 NC_009801.1 1981603 1982550 R identified by match to protein family HMM PF00294; PfkB family kinase complement(1981603..1982550) Escherichia coli E24377A 5590017 YP_001463072.1 CDS EcE24377A_1997 NC_009801.1 1982555 1983391 R identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; fructose-bisphosphate aldolase complement(1982555..1983391) Escherichia coli E24377A 5588739 YP_001463073.1 CDS gutB NC_009801.1 1983412 1984455 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; sorbitol dehydrogenase complement(1983412..1984455) Escherichia coli E24377A 5589857 YP_001463074.1 CDS ydjK NC_009801.1 1984472 1985851 R identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator family transporter complement(1984472..1985851) Escherichia coli E24377A 5589831 YP_001463075.1 CDS EcE24377A_2000 NC_009801.1 1985878 1986954 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; zinc-binding dehydrogenase oxidoreductase complement(1985878..1986954) Escherichia coli E24377A 5588709 YP_001463076.1 CDS EcE24377A_2001 NC_009801.1 1987324 1987596 R identified by match to protein family HMM PF07023; hypothetical protein complement(1987324..1987596) Escherichia coli E24377A 5587234 YP_001463077.1 CDS msrB NC_009801.1 1987638 1988051 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(1987638..1988051) Escherichia coli E24377A 5588805 YP_001463078.1 CDS gapA NC_009801.1 1988393 1989388 D identified by similarity to SP:P0A9B2; match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; giyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 1988393..1989388 Escherichia coli E24377A 5590753 YP_001463079.1 CDS EcE24377A_2004 NC_009801.1 1989451 1990356 D identified by match to protein family HMM PF01263; aldose 1-epimerase 1989451..1990356 Escherichia coli E24377A 5587484 YP_001463080.1 CDS EcE24377A_2005 NC_009801.1 1990407 1991261 R identified by match to protein family HMM PF00248; aldo/keto reductase complement(1990407..1991261) Escherichia coli E24377A 5588348 YP_001463081.1 CDS mipA NC_009801.1 1991351 1992097 R identified by similarity to SP:P0A908; match to protein family HMM PF06629; MltA-interacting protein MipA complement(1991351..1992097) Escherichia coli E24377A 5589792 YP_001463082.1 CDS EcE24377A_2007 NC_009801.1 1992533 1994467 D identified by match to protein family HMM PF06798; match to protein family HMM PF08298; serine kinase 1992533..1994467 Escherichia coli E24377A 5587613 YP_001463083.1 CDS EcE24377A_2008 NC_009801.1 1994580 1995863 D identified by match to protein family HMM PF04285; hypothetical protein 1994580..1995863 Escherichia coli E24377A 5588871 YP_001463084.1 CDS EcE24377A_2009 NC_009801.1 1996010 1997485 D identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 1996010..1997485 Escherichia coli E24377A 5588197 YP_001463085.1 CDS EcE24377A_2010 NC_009801.1 1997666 1999156 D identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 1997666..1999156 Escherichia coli E24377A 5588264 YP_001463086.1 CDS EcE24377A_2011 NC_009801.1 1999199 1999702 D identified by match to protein family HMM PF04073; prolyl-tRNA synthetase 1999199..1999702 Escherichia coli E24377A 5589973 YP_001463087.1 CDS EcE24377A_2012 NC_009801.1 1999703 1999855 R identified by similarity to GB:AAZ88084.1; hypothetical protein complement(1999703..1999855) Escherichia coli E24377A 5588819 YP_001463088.1 CDS EcE24377A_2014 NC_009801.1 1999977 2000423 D identified by similarity to SP:P0ACY8; match to protein family HMM PF04284; hypothetical protein 1999977..2000423 Escherichia coli E24377A 5588703 YP_001463089.1 CDS yeaN NC_009801.1 2001298 2002479 D identified by similarity to SP:P76242; match to protein family HMM PF07690; match to protein family HMM TIGR00896; inner membrane transport protein yeaN 2001298..2002479 Escherichia coli E24377A 5589672 YP_001463090.1 CDS EcE24377A_2016 NC_009801.1 2002534 2002881 D identified by match to protein family HMM PF04343; hypothetical protein 2002534..2002881 Escherichia coli E24377A 5586114 YP_001463091.1 CDS EcE24377A_2017 NC_009801.1 2002903 2003157 R identified by match to protein family HMM PF03891; lipoprotein complement(2002903..2003157) Escherichia coli E24377A 5590645 YP_001463092.1 CDS EcE24377A_2018 NC_009801.1 2003211 2004365 D identified by match to protein family HMM PF00990; match to protein family HMM PF01590; match to protein family HMM TIGR00254; GAF domain/diguanylate cyclase domain-containing protein 2003211..2004365 Escherichia coli E24377A 5586438 YP_001463093.1 CDS EcE24377A_2019 NC_009801.1 2004383 2004496 D identified by glimmer; hypothetical protein 2004383..2004496 Escherichia coli E24377A 5586848 YP_001463094.1 CDS EcE24377A_2020 NC_009801.1 2004632 2004880 R identified by match to protein family HMM PF04226; hypothetical protein complement(2004632..2004880) Escherichia coli E24377A 5588023 YP_001463095.1 CDS EcE24377A_2021 NC_009801.1 2004892 2005047 R identified by glimmer; hypothetical protein complement(2004892..2005047) Escherichia coli E24377A 5587609 YP_001463096.1 CDS EcE24377A_2022 NC_009801.1 2005107 2006315 R identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766; IS605 family transposase OrfB complement(2005107..2006315) Escherichia coli E24377A 5588636 YP_001463097.1 CDS EcE24377A_2023 NC_009801.1 2006338 2007285 D identified by match to protein family HMM PF01797; IS605 family transposase 2006338..2007285 Escherichia coli E24377A 5587940 YP_001463098.1 CDS EcE24377A_2024 NC_009801.1 2007494 2008132 R identified by match to protein family HMM PF01810; leucine export protein LeuE complement(2007494..2008132) Escherichia coli E24377A 5586736 YP_001463099.1 CDS EcE24377A_2025 NC_009801.1 2008259 2009182 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(2008259..2009182) Escherichia coli E24377A 5589869 YP_001463100.1 CDS ttuC NC_009801.1 2009285 2010370 D identified by similarity to SP:Q51945; match to protein family HMM PF00180; match to protein family HMM TIGR02089; tartrate dehydrogenase/decarboxylase 2009285..2010370 Escherichia coli E24377A 5590704 YP_001463101.1 CDS EcE24377A_2027 NC_009801.1 2010621 2012231 D member of the betaine, carnitine, choline transporter (BCCT) family; unknown function; transporter 2010621..2012231 Escherichia coli E24377A 5586358 YP_001463102.1 CDS EcE24377A_2028 NC_009801.1 2012263 2013387 D identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 2012263..2013387 Escherichia coli E24377A 5586618 YP_001463103.1 CDS EcE24377A_2029 NC_009801.1 2013443 2014408 D identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; oxidoreductase, FAD/NAD-binding/iron-sulfur cluster binding protein 2013443..2014408 Escherichia coli E24377A 5586510 YP_001463104.1 CDS rnd NC_009801.1 2014462 2015589 R identified by match to protein family HMM PF00570; match to protein family HMM PF01612; match to protein family HMM TIGR01388; ribonuclease D complement(2014462..2015589) Escherichia coli E24377A 5588539 YP_001463105.1 CDS fadD NC_009801.1 2015659 2017344 R Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(2015659..2017344) Escherichia coli E24377A 5588458 YP_001463106.1 CDS slp NC_009801.1 2017549 2018130 R identified by similarity to SP:P37194; match to protein family HMM PF03843; match to protein family HMM TIGR00752; outer membrane protein Slp complement(2017549..2018130) Escherichia coli E24377A 5588656 YP_001463107.1 CDS EcE24377A_2033 NC_009801.1 2018170 2018865 R identified by match to protein family HMM PF00814; glycoprotease complement(2018170..2018865) Escherichia coli E24377A 5588556 YP_001463108.1 CDS EcE24377A_2034 NC_009801.1 2018923 2020833 R hypothetical protein complement(2018923..2020833) Escherichia coli E24377A 5586498 YP_001463109.1 CDS EcE24377A_2035 NC_009801.1 2020866 2021252 R identified by glimmer; hypothetical protein complement(2020866..2021252) Escherichia coli E24377A 5586297 YP_001463110.1 CDS EcE24377A_2036 NC_009801.1 2020965 2021309 D identified by match to protein family HMM PF01042; endoribonuclease L-PSP 2020965..2021309 Escherichia coli E24377A 5590587 YP_001463111.1 CDS EcE24377A_2037 NC_009801.1 2021343 2021480 R identified by glimmer; hypothetical protein complement(2021343..2021480) Escherichia coli E24377A 5590284 YP_001463112.1 CDS EcE24377A_2038 NC_009801.1 2021671 2022030 D identified by similarity to SP:P64492; match to protein family HMM PF08986; hypothetical protein 2021671..2022030 Escherichia coli E24377A 5585921 YP_001463113.1 CDS EcE24377A_2039 NC_009801.1 2022150 2022329 R identified by similarity to SP:P67338; match to protein family HMM PF03701; hypothetical protein complement(2022150..2022329) Escherichia coli E24377A 5590368 YP_001463114.1 CDS pabB NC_009801.1 2022403 2023764 D identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553; para-aminobenzoate synthase component I 2022403..2023764 Escherichia coli E24377A 5588725 YP_001463115.1 CDS EcE24377A_2041 NC_009801.1 2023768 2024346 D identified by match to protein family HMM PF00293; hypothetical protein 2023768..2024346 Escherichia coli E24377A 5587509 YP_001463116.1 CDS sdaA NC_009801.1 2024530 2025894 D identified by similarity to SP:P16095; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; L-serine dehydratase 1 2024530..2025894 Escherichia coli E24377A 5589468 YP_001463117.1 CDS EcE24377A_2044 NC_009801.1 2027626 2029182 R identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741; TerC family/CBS/transporter associated domain-containing protein complement(2027626..2029182) Escherichia coli E24377A 5586573 YP_001463118.1 CDS manX NC_009801.1 2029645 2030616 D identified by match to protein family HMM PF03610; match to protein family HMM PF03830; match to protein family HMM TIGR00824; match to protein family HMM TIGR00854; PTS system mannose-specific transporter subunit IIAB 2029645..2030616 Escherichia coli E24377A 5589279 YP_001463119.1 CDS manY NC_009801.1 2030679 2031479 D identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822; PTS system mannose-specific transporter subunit IIC 2030679..2031479 Escherichia coli E24377A 5587087 YP_001463120.1 CDS manZ NC_009801.1 2031492 2032343 D hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 2031492..2032343 Escherichia coli E24377A 5588601 YP_001463121.1 CDS EcE24377A_2048 NC_009801.1 2032398 2032856 D identified by similarity to SP:Q8ZP01; match to protein family HMM PF06173; hypothetical protein 2032398..2032856 Escherichia coli E24377A 5586052 YP_001463122.1 CDS EcE24377A_2050 NC_009801.1 2033286 2033852 D membrane protein YebN; hypothetical protein 2033286..2033852 Escherichia coli E24377A 5590308 YP_001463123.1 CDS rrmA NC_009801.1 2033849 2034658 R methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase complement(2033849..2034658) Escherichia coli E24377A 5589757 YP_001463124.1 CDS cspC NC_009801.1 2034824 2035033 R identified by similarity to SP:P0A9Y6; match to protein family HMM PF00313; cold shock-like protein CspC complement(2034824..2035033) Escherichia coli E24377A 5589905 YP_001463125.1 CDS EcE24377A_2052 NC_009801.1 2035046 2035189 R identified by similarity to SP:P64511; hypothetical protein complement(2035046..2035189) Escherichia coli E24377A 5589627 YP_001463126.1 CDS EcE24377A_2053 NC_009801.1 2035859 2036146 R identified by similarity to SP:P64499; hypothetical protein complement(2035859..2036146) Escherichia coli E24377A 5585987 YP_001463127.1 CDS EcE24377A_2054 NC_009801.1 2036221 2036364 R hypothetical protein complement(2036221..2036364) Escherichia coli E24377A 5590304 YP_001463128.1 CDS EcE24377A_2055 NC_009801.1 2036523 2036762 D identified by similarity to GB:ABB62074.1; hypothetical protein 2036523..2036762 Escherichia coli E24377A 5586181 YP_001463129.1 CDS kdgR NC_009801.1 2036905 2037696 R identified by similarity to SP:P76268; match to protein family HMM PF01614; match to protein family HMM PF09339; transcriptional regulator KdgR complement(2036905..2037696) Escherichia coli E24377A 5589019 YP_001463130.1 CDS EcE24377A_2057 NC_009801.1 2037873 2039246 D identified by match to protein family HMM PF07690; major facilitator transporter 2037873..2039246 Escherichia coli E24377A 5589430 YP_001463131.1 CDS EcE24377A_2058 NC_009801.1 2039292 2040173 R metalloprotease; heat shock protein HtpX complement(2039292..2040173) Escherichia coli E24377A 5587281 YP_001463132.1 CDS prc NC_009801.1 2040365 2042413 R Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease complement(2040365..2042413) Escherichia coli E24377A 5589847 YP_001463133.1 CDS proQ NC_009801.1 2042433 2043131 R affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector complement(2042433..2043131) Escherichia coli E24377A 5586643 YP_001463134.1 CDS EcE24377A_2061 NC_009801.1 2043228 2043779 R identified by match to protein family HMM PF01590; GAF domain-containing protein complement(2043228..2043779) Escherichia coli E24377A 5588884 YP_001463135.1 CDS EcE24377A_2062 NC_009801.1 2043855 2045138 D identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155; PqiA family integral membrane protein 2043855..2045138 Escherichia coli E24377A 5589245 YP_001463136.1 CDS EcE24377A_2063 NC_009801.1 2045101 2047740 D identified by match to protein family HMM PF02470; mce-like protein 2045101..2047740 Escherichia coli E24377A 5588760 YP_001463137.1 CDS yebU NC_009801.1 2047814 2049259 D in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 2047814..2049259 Escherichia coli E24377A 5590679 YP_001463138.1 CDS EcE24377A_2065 NC_009801.1 2049377 2049613 D identified by match to protein family HMM PF07351; hypothetical protein 2049377..2049613 Escherichia coli E24377A 5587962 YP_001463139.1 CDS EcE24377A_2066 NC_009801.1 2049634 2049909 D identified by match to protein family HMM PF07358; hypothetical protein 2049634..2049909 Escherichia coli E24377A 5588858 YP_001463140.1 CDS pphA NC_009801.1 2049910 2050566 R Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 complement(2049910..2050566) Escherichia coli E24377A 5589311 YP_001463141.1 CDS EcE24377A_2068 NC_009801.1 2050962 2051303 R identified by similarity to GB:ABB61282.1; hypothetical protein complement(2050962..2051303) Escherichia coli E24377A 5587945 YP_001463142.1 CDS EcE24377A_2069 NC_009801.1 2051316 2052188 R identified by match to protein family HMM PF05425; copper resistance protein D complement(2051316..2052188) Escherichia coli E24377A 5588759 YP_001463143.1 CDS EcE24377A_2070 NC_009801.1 2052192 2052566 R identified by match to protein family HMM PF04234; hypothetical protein complement(2052192..2052566) Escherichia coli E24377A 5590070 YP_001463144.1 CDS holE NC_009801.1 2052705 2052935 D identified by similarity to SP:P0ABT1; match to protein family HMM PF06440; DNA polymerase III subunit theta 2052705..2052935 Escherichia coli E24377A 5588191 YP_001463145.1 CDS EcE24377A_2072 NC_009801.1 2053037 2053693 D identified by match to protein family HMM PF00795; carbon-nitrogen family hydrolase 2053037..2053693 Escherichia coli E24377A 5587307 YP_001463146.1 CDS exoX NC_009801.1 2053717 2054379 D 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 2053717..2054379 Escherichia coli E24377A 5587912 YP_001463147.1 CDS prtB NC_009801.1 2054376 2056436 R PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 complement(2054376..2056436) Escherichia coli E24377A 5590483 YP_001463148.1 CDS EcE24377A_2075 NC_009801.1 2056645 2057304 R identified by match to protein family HMM PF04391; hypothetical protein complement(2056645..2057304) Escherichia coli E24377A 5589557 YP_001463149.1 CDS EcE24377A_2076 NC_009801.1 2057364 2057474 D identified by glimmer; hypothetical protein 2057364..2057474 Escherichia coli E24377A 5587137 YP_001463150.1 CDS EcE24377A_2077 NC_009801.1 2057631 2057987 R secreted protein; unknown function; hypothetical protein complement(2057631..2057987) Escherichia coli E24377A 5590407 YP_001463151.1 CDS EcE24377A_2078 NC_009801.1 2058054 2058344 R identified by similarity to SP:P0ACY9; match to protein family HMM PF07130; DNA damage-inducible protein YebG complement(2058054..2058344) Escherichia coli E24377A 5586245 YP_001463152.1 CDS purT NC_009801.1 2058478 2059656 D non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 2058478..2059656 Escherichia coli E24377A 5589121 YP_001463153.1 CDS eda NC_009801.1 2059712 2060353 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(2059712..2060353) Escherichia coli E24377A 5587287 YP_001463154.1 CDS edd NC_009801.1 2060390 2062201 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(2060390..2062201) Escherichia coli E24377A 5588546 YP_001463155.1 CDS zwf NC_009801.1 2062436 2063911 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(2062436..2063911) Escherichia coli E24377A 5590650 YP_001463156.1 CDS EcE24377A_2083 NC_009801.1 2064249 2065118 D Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 2064249..2065118 Escherichia coli E24377A 5589146 YP_001463157.1 CDS pykA NC_009801.1 2065246 2066688 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2065246..2066688 Escherichia coli E24377A 5590851 YP_001463158.1 CDS msbB1 NC_009801.1 2066819 2067790 R Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase complement(2066819..2067790) Escherichia coli E24377A 5587695 YP_001463159.1 CDS EcE24377A_2086 NC_009801.1 2067910 2069232 R identified by match to protein family HMM PF01476; match to protein family HMM PF01551; match to protein family HMM PF04225; match to protein family HMM PF08525; hypothetical protein complement(2067910..2069232) Escherichia coli E24377A 5589219 YP_001463160.1 CDS znuA NC_009801.1 2069248 2070180 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein complement(2069248..2070180) Escherichia coli E24377A 5589876 YP_001463161.1 CDS znuC NC_009801.1 2070259 2071014 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 2070259..2071014 Escherichia coli E24377A 5590827 YP_001463162.1 CDS znuB NC_009801.1 2071011 2071796 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 2071011..2071796 Escherichia coli E24377A 5587722 YP_001463163.1 CDS ruvB NC_009801.1 2071943 2072953 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(2071943..2072953) Escherichia coli E24377A 5587409 YP_001463164.1 CDS ruvA NC_009801.1 2072962 2073573 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(2072962..2073573) Escherichia coli E24377A 5586077 YP_001463165.1 CDS EcE24377A_2092 NC_009801.1 2073731 2074450 D identified by match to protein family HMM PF06520; hypothetical protein 2073731..2074450 Escherichia coli E24377A 5586526 YP_001463166.1 CDS ruvC NC_009801.1 2074452 2074973 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(2074452..2074973) Escherichia coli E24377A 5588650 YP_001463167.1 CDS EcE24377A_2094 NC_009801.1 2075008 2075748 R identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein complement(2075008..2075748) Escherichia coli E24377A 5587093 YP_001463168.1 CDS ntpA NC_009801.1 2075777 2076229 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(2075777..2076229) Escherichia coli E24377A 5589439 YP_001463169.1 CDS aspS NC_009801.1 2076347 2078119 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(2076347..2078119) Escherichia coli E24377A 5588589 YP_001463170.1 CDS EcE24377A_2097 NC_009801.1 2078309 2078404 R identified by glimmer; hypothetical protein complement(2078309..2078404) Escherichia coli E24377A 5588414 YP_001463171.1 CDS EcE24377A_2098 NC_009801.1 2078429 2078995 D identified by match to protein family HMM PF00857; hypothetical protein 2078429..2078995 Escherichia coli E24377A 5586097 YP_001463172.1 CDS EcE24377A_2099 NC_009801.1 2078992 2079810 D identified by similarity to SP:P37348; match to protein family HMM PF01904; hypothetical protein 2078992..2079810 Escherichia coli E24377A 5590509 YP_001463173.1 CDS EcE24377A_2100 NC_009801.1 2079863 2080258 D identified by similarity to SP:P64515; inner membrane protein 2079863..2080258 Escherichia coli E24377A 5587895 YP_001463174.1 CDS EcE24377A_2101 NC_009801.1 2080299 2081042 D identified by match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00740; methyltransferase 2080299..2081042 Escherichia coli E24377A 5589426 YP_001463175.1 CDS EcE24377A_2102 NC_009801.1 2081039 2082010 D identified by match to protein family HMM PF08003; match to protein family HMM PF08241; match to protein family HMM TIGR00452; methyltransferase 2081039..2082010 Escherichia coli E24377A 5587848 YP_001463176.1 CDS EcE24377A_2104 NC_009801.1 2082038 2082184 D identified by glimmer; hypothetical protein 2082038..2082184 Escherichia coli E24377A 5590021 YP_001463177.1 CDS torZ NC_009801.1 2082175 2084622 R identified by similarity to SP:P46923; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409; trimethylamine N-oxide reductase III subunit TorZ complement(2082175..2084622) Escherichia coli E24377A 5586682 YP_001463178.1 CDS torY NC_009801.1 2084629 2085729 R identified by similarity to SP:P52005; match to protein family HMM PF03264; trimethylamine N-oxide reductase III, c-type cytochrome subunit TorY complement(2084629..2085729) Escherichia coli E24377A 5590576 YP_001463179.1 CDS cutC NC_009801.1 2086117 2086863 R identified by match to protein family HMM PF03932; copper homeostasis protein CutC complement(2086117..2086863) Escherichia coli E24377A 5590638 YP_001463180.1 CDS EcE24377A_2107 NC_009801.1 2086877 2087449 R identified by similarity to GB:AAL20824.1; match to protein family HMM PF06185; hypothetical protein complement(2086877..2087449) Escherichia coli E24377A 5589580 YP_001463181.1 CDS argS NC_009801.1 2087659 2089392 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2087659..2089392 Escherichia coli E24377A 5586887 YP_001463182.1 CDS EcE24377A_2109 NC_009801.1 2089569 2090057 D identified by match to protein family HMM PF07007; hypothetical protein 2089569..2090057 Escherichia coli E24377A 5589059 YP_001463183.1 CDS flhE NC_009801.1 2090177 2090569 R identified by similarity to SP:P76297; match to protein family HMM PF06366; flagellar protein FlhE complement(2090177..2090569) Escherichia coli E24377A 5590453 YP_001463184.1 CDS flhA NC_009801.1 2090569 2092647 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(2090569..2092647) Escherichia coli E24377A 5589984 YP_001463185.1 CDS flhB NC_009801.1 2092640 2093788 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(2092640..2093788) Escherichia coli E24377A 5587138 YP_001463186.1 CDS EcE24377A_2113 NC_009801.1 2093821 2093955 D identified by glimmer; hypothetical protein 2093821..2093955 Escherichia coli E24377A 5587543 YP_001463187.1 CDS cheZ NC_009801.1 2093990 2094634 R cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ complement(2093990..2094634) Escherichia coli E24377A 5588220 YP_001463188.1 CDS cheY NC_009801.1 2094645 2095034 R chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY complement(2094645..2095034) Escherichia coli E24377A 5588305 YP_001463189.1 CDS cheB NC_009801.1 2095049 2096098 R regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase complement(2095049..2096098) Escherichia coli E24377A 5588888 YP_001463190.1 CDS cheR NC_009801.1 2096101 2096961 R methylates the MCP; chemotaxis methyltransferase CheR complement(2096101..2096961) Escherichia coli E24377A 5587473 YP_001463191.1 CDS EcE24377A_2118 NC_009801.1 2096980 2098581 R mediates taxis toward dipeptides; methyl-accepting protein IV complement(2096980..2098581) Escherichia coli E24377A 5587577 YP_001463192.1 CDS cheM NC_009801.1 2098627 2100288 R identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203; methyl-accepting chemotaxis protein II complement(2098627..2100288) Escherichia coli E24377A 5586642 YP_001463193.1 CDS cheW NC_009801.1 2100433 2100936 R identified by match to protein family HMM PF01584; purine-binding chemotaxis protein complement(2100433..2100936) Escherichia coli E24377A 5590254 YP_001463194.1 CDS cheA NC_009801.1 2100957 2102921 R chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA complement(2100957..2102921) Escherichia coli E24377A 5587109 YP_001463195.1 CDS motB NC_009801.1 2102926 2103852 R with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB complement(2102926..2103852) Escherichia coli E24377A 5588052 YP_001463196.1 CDS motA NC_009801.1 2103849 2104736 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(2103849..2104736) Escherichia coli E24377A 5589375 YP_001463197.1 CDS flhC NC_009801.1 2104863 2105441 R With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC complement(2104863..2105441) Escherichia coli E24377A 5589187 YP_001463198.1 CDS flhD NC_009801.1 2105444 2105794 R with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD complement(2105444..2105794) Escherichia coli E24377A 5590412 YP_001463199.1 CDS EcE24377A_2126 NC_009801.1 2105825 2105923 R identified by glimmer; hypothetical protein complement(2105825..2105923) Escherichia coli E24377A 5589060 YP_001463200.1 CDS uspC NC_009801.1 2106574 2107002 D ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 2106574..2107002 Escherichia coli E24377A 5590223 YP_001463201.1 CDS otsA NC_009801.1 2107009 2108433 R identified by match to protein family HMM PF00982; match to protein family HMM TIGR02400; trehalose-6-phosphate synthase complement(2107009..2108433) Escherichia coli E24377A 5589913 YP_001463202.1 CDS otsB NC_009801.1 2108408 2109208 R biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase complement(2108408..2109208) Escherichia coli E24377A 5589403 YP_001463203.1 CDS araH NC_009801.1 2109375 2110361 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease complement(2109375..2110361) Escherichia coli E24377A 5587198 YP_001463204.1 CDS araG NC_009801.1 2110376 2111890 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein complement(2110376..2111890) Escherichia coli E24377A 5587532 YP_001463205.1 CDS araF NC_009801.1 2111960 2112949 R identified by match to protein family HMM PF00532; L-arabinose ABC transporter periplasmic L-arabinose-binding protein complement(2111960..2112949) Escherichia coli E24377A 5585995 YP_001463206.1 CDS EcE24377A_2133 NC_009801.1 2113746 2114249 D identified by match to protein family HMM PF00210; ferritin 2113746..2114249 Escherichia coli E24377A 5588260 YP_001463208.1 CDS EcE24377A_2135 NC_009801.1 2114691 2114837 D identified by glimmer; hypothetical protein 2114691..2114837 Escherichia coli E24377A 5589838 YP_001463209.1 CDS EcE24377A_2136 NC_009801.1 2115043 2115366 D lipoprotein 2115043..2115366 Escherichia coli E24377A 5586315 YP_001463210.1 CDS EcE24377A_2137 NC_009801.1 2115372 2115512 R identified by glimmer; hypothetical protein complement(2115372..2115512) Escherichia coli E24377A 5586670 YP_001463211.1 CDS ftnA NC_009801.1 2115537 2116034 D cytoplasmic iron storage protein; ferritin 2115537..2116034 Escherichia coli E24377A 5587929 YP_001463212.1 CDS EcE24377A_2139 NC_009801.1 2116072 2116311 R identified by similarity to SP:P46887; hypothetical protein complement(2116072..2116311) Escherichia coli E24377A 5589280 YP_001463213.1 CDS tyrP NC_009801.1 2116502 2117713 D identified by match to protein family HMM PF01490; match to protein family HMM PF03222; match to protein family HMM TIGR00837; tyrosine-specific transport protein 2116502..2117713 Escherichia coli E24377A 5589087 YP_001463214.1 CDS EcE24377A_2141 NC_009801.1 2117775 2118440 R identified by match to protein family HMM PF02810; match to protein family HMM TIGR02292; hypothetical protein complement(2117775..2118440) Escherichia coli E24377A 5588764 YP_001463215.1 CDS pgsA NC_009801.1 2119090 2119638 R identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; phosphatidylglycerophosphate synthetase complement(2119090..2119638) Escherichia coli E24377A 5587026 YP_001463216.1 CDS uvrC NC_009801.1 2119695 2121527 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(2119695..2121527) Escherichia coli E24377A 5587924 YP_001463217.1 CDS uvrY NC_009801.1 2121524 2122180 R in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator complement(2121524..2122180) Escherichia coli E24377A 5589434 YP_001463218.1 CDS EcE24377A_2148 NC_009801.1 2122419 2122547 R hypothetical protein complement(2122419..2122547) Escherichia coli E24377A 5585911 YP_001463219.1 CDS EcE24377A_2149 NC_009801.1 2122639 2122863 D identified by similarity to SP:P0AD09; hypothetical protein 2122639..2122863 Escherichia coli E24377A 5586864 YP_001463220.1 CDS sdiA NC_009801.1 2122930 2123652 R regulates genes involved in cell division; DNA-binding transcriptional activator SdiA complement(2122930..2123652) Escherichia coli E24377A 5588254 YP_001463221.1 CDS yecC NC_009801.1 2123882 2124634 R identified by match to protein family HMM PF00005; amino-acid ABC transporter ATP-binding protein YecC complement(2123882..2124634) Escherichia coli E24377A 5587802 YP_001463222.1 CDS EcE24377A_2152 NC_009801.1 2124631 2125299 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; L-cystine ABC transporter permease complement(2124631..2125299) Escherichia coli E24377A 5586444 YP_001463223.1 CDS dcyD NC_009801.1 2125271 2126299 R catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase complement(2125271..2126299) Escherichia coli E24377A 5587919 YP_001463224.1 CDS fliY NC_009801.1 2126404 2127204 R identified by match to protein family HMM PF00497; cystine transporter subunit complement(2126404..2127204) Escherichia coli E24377A 5590514 YP_001463225.1 CDS EcE24377A_2155 NC_009801.1 2127328 2127843 R expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ complement(2127328..2127843) Escherichia coli E24377A 5590057 YP_001463226.1 CDS fliA NC_009801.1 2127889 2128608 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor complement(2127889..2128608) Escherichia coli E24377A 5586823 YP_001463227.1 CDS EcE24377A_2157 NC_009801.1 2128679 2128879 R identified by glimmer; hypothetical protein complement(2128679..2128879) Escherichia coli E24377A 5589560 YP_001463228.1 CDS fliC NC_009801.1 2128928 2130667 R structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin complement(2128928..2130667) Escherichia coli E24377A 5586916 YP_001463229.1 CDS fliD NC_009801.1 2130933 2132339 D involved in flagellin assembly; flagellar capping protein 2130933..2132339 Escherichia coli E24377A 5587946 YP_001463230.1 CDS fliS NC_009801.1 2132364 2132774 D flagellin specific chaperone; flagellar protein FliS 2132364..2132774 Escherichia coli E24377A 5588852 YP_001463231.1 CDS fliT NC_009801.1 2132774 2133139 D binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2132774..2133139 Escherichia coli E24377A 5590115 YP_001463232.1 CDS amyA NC_009801.1 2133217 2134704 D converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 2133217..2134704 Escherichia coli E24377A 5589383 YP_001463233.1 CDS EcE24377A_2163 NC_009801.1 2134738 2135154 R hypothetical protein complement(2134738..2135154) Escherichia coli E24377A 5586578 YP_001463234.1 CDS EcE24377A_2164 NC_009801.1 2135338 2136543 D identified by match to protein family HMM PF04143; inner membrane protein 2135338..2136543 Escherichia coli E24377A 5586731 YP_001463235.1 CDS EcE24377A_2165 NC_009801.1 2136540 2136773 D identified by match to protein family HMM PF01206; hypothetical protein 2136540..2136773 Escherichia coli E24377A 5587611 YP_001463236.1 CDS EcE24377A_2167 NC_009801.1 2136882 2137553 D identified by similarity to GB:AAG56946.1; match to protein family HMM PF02586; hypothetical protein 2136882..2137553 Escherichia coli E24377A 5590207 YP_001463237.1 CDS EcE24377A_2166 NC_009801.1 2137538 2138701 R identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766; IS605 family transposase OrfB complement(2137538..2138701) Escherichia coli E24377A 5585939 YP_001463238.1 CDS EcE24377A_2169 NC_009801.1 2140090 2140887 R AraC family transcriptional regulator complement(2140090..2140887) Escherichia coli E24377A 5588545 YP_001463239.1 CDS fliE NC_009801.1 2142283 2142597 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(2142283..2142597) Escherichia coli E24377A 5589817 YP_001463240.1 CDS fliF NC_009801.1 2142812 2144470 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2142812..2144470 Escherichia coli E24377A 5590716 YP_001463241.1 CDS fliG NC_009801.1 2144463 2145458 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2144463..2145458 Escherichia coli E24377A 5588558 YP_001463242.1 CDS fliH NC_009801.1 2145451 2146137 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2145451..2146137 Escherichia coli E24377A 5586314 YP_001463243.1 CDS fliI NC_009801.1 2146137 2147510 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2146137..2147510 Escherichia coli E24377A 5589775 YP_001463244.1 CDS fliJ NC_009801.1 2147529 2147972 D rod/hook and filament chaperone; flagellar biosynthesis chaperone 2147529..2147972 Escherichia coli E24377A 5586137 YP_001463245.1 CDS fliK NC_009801.1 2147969 2149096 D identified by similarity to SP:P52614; match to protein family HMM PF02120; flagellar hook-length control protein 2147969..2149096 Escherichia coli E24377A 5587347 YP_001463246.1 CDS fliL NC_009801.1 2149201 2149665 D interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body protein FliL 2149201..2149665 Escherichia coli E24377A 5590633 YP_001463247.1 CDS fliM NC_009801.1 2149670 2150674 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2149670..2150674 Escherichia coli E24377A 5589633 YP_001463248.1 CDS fliN NC_009801.1 2150671 2151084 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2150671..2151084 Escherichia coli E24377A 5589716 YP_001463249.1 CDS fliO NC_009801.1 2151087 2151452 D with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2151087..2151452 Escherichia coli E24377A 5590552 YP_001463250.1 CDS fliP NC_009801.1 2151452 2152189 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2151452..2152189 Escherichia coli E24377A 5587069 YP_001463251.1 CDS fliQ NC_009801.1 2152199 2152468 D with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2152199..2152468 Escherichia coli E24377A 5590232 YP_001463252.1 CDS fliR NC_009801.1 2152477 2153262 D FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2152477..2153262 Escherichia coli E24377A 5587186 YP_001463253.1 CDS rcsA NC_009801.1 2153552 2154175 D identified by match to protein family HMM PF00196; colanic acid capsular biosynthesis activation protein A 2153552..2154175 Escherichia coli E24377A 5590058 YP_001463254.1 CDS EcE24377A_2185 NC_009801.1 2154219 2154407 R identified by similarity to OMNI:NTL01SF1877; hypothetical protein complement(2154219..2154407) Escherichia coli E24377A 5585934 YP_001463255.1 CDS EcE24377A_2186 NC_009801.1 2154570 2154797 D hypothetical protein 2154570..2154797 Escherichia coli E24377A 5587013 YP_001463256.1 CDS EcE24377A_2188 NC_009801.1 2155095 2155910 D catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2155095..2155910 Escherichia coli E24377A 5587260 YP_001463257.1 CDS EcE24377A_2187 NC_009801.1 2155907 2157583 R identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase complement(2155907..2157583) Escherichia coli E24377A 5586255 YP_001463258.1 CDS EcE24377A_2189 NC_009801.1 2157772 2157954 R identified by similarity to GB:AAP17372.1; hypothetical protein complement(2157772..2157954) Escherichia coli E24377A 5587989 YP_001463259.1 CDS EcE24377A_2190 NC_009801.1 2158033 2158950 R identified by match to protein family HMM PF05661; hypothetical protein complement(2158033..2158950) Escherichia coli E24377A 5589546 YP_001463260.1 CDS EcE24377A_2192 NC_009801.1 2159123 2160043 D identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950; hypothetical protein 2159123..2160043 Escherichia coli E24377A 5589875 YP_001463261.1 CDS vsr NC_009801.1 2160032 2160502 R identified by similarity to SP:P09184; match to protein family HMM PF03852; match to protein family HMM TIGR00632; very short patch repair protein complement(2160032..2160502) Escherichia coli E24377A 5589436 YP_001463262.1 CDS dcm NC_009801.1 2160483 2161901 R identified by similarity to SP:P0AED9; match to protein family HMM PF00145; match to protein family HMM TIGR00675; DNA cytosine methylase complement(2160483..2161901) Escherichia coli E24377A 5590825 YP_001463263.1 CDS EcE24377A_2194 NC_009801.1 2161968 2162663 R identified by match to protein family HMM PF01966; hypothetical protein complement(2161968..2162663) Escherichia coli E24377A 5589267 YP_001463264.1 CDS EcE24377A_2195 NC_009801.1 2162703 2163086 R hypothetical protein complement(2162703..2163086) Escherichia coli E24377A 5587758 YP_001463265.1 CDS EcE24377A_2196 NC_009801.1 2163070 2163177 D identified by glimmer; hypothetical protein 2163070..2163177 Escherichia coli E24377A 5589779 YP_001463266.1 CDS EcE24377A_2197 NC_009801.1 2163636 2164709 D identified by match to protein family HMM PF00267; match to protein family HMM TIGR03304; outer membrane protein 2163636..2164709 Escherichia coli E24377A 5586003 YP_001463267.1 CDS hchA NC_009801.1 2165301 2166152 D Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2165301..2166152 Escherichia coli E24377A 5588379 YP_001463268.1 CDS EcE24377A_2199 NC_009801.1 2166260 2167618 R identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386; heavy metal sensor histidine kinase complement(2166260..2167618) Escherichia coli E24377A 5587264 YP_001463269.1 CDS EcE24377A_2200 NC_009801.1 2167618 2168400 R induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW complement(2167618..2168400) Escherichia coli E24377A 5589565 YP_001463270.1 CDS EcE24377A_2201 NC_009801.1 2168422 2168835 D identified by match to protein family HMM PF00576; match to protein family HMM TIGR02962; transthyretin family protein 2168422..2168835 Escherichia coli E24377A 5587696 YP_001463271.1 CDS EcE24377A_2202 NC_009801.1 2168944 2169948 D in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 2168944..2169948 Escherichia coli E24377A 5586868 YP_001463272.1 CDS EcE24377A_2203 NC_009801.1 2169949 2170584 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 2169949..2170584 Escherichia coli E24377A 5587012 YP_001463273.1 CDS EcE24377A_2204 NC_009801.1 2170841 2171491 D identified by similarity to SP:P76344; match to protein family HMM PF09223; hypothetical protein 2170841..2171491 Escherichia coli E24377A 5590672 YP_001463274.1 CDS EcE24377A_2205 NC_009801.1 2171834 2172364 D identified by match to protein family HMM PF01292; nickel-dependent hydrogenase, b-type cytochrome subunit 2171834..2172364 Escherichia coli E24377A 5589719 YP_001463275.1 CDS EcE24377A_2206 NC_009801.1 2173089 2173205 R identified by glimmer; hypothetical protein complement(2173089..2173205) Escherichia coli E24377A 5590537 YP_001463276.1 CDS EcE24377A_2207 NC_009801.1 2173343 2174353 R identified by similarity to SP:P03764; match to protein family HMM PF08400; tail fiber family protein complement(2173343..2174353) Escherichia coli E24377A 5590540 YP_001463277.1 CDS EcE24377A_2209 NC_009801.1 2175399 2175491 R identified by glimmer; hypothetical protein complement(2175399..2175491) Escherichia coli E24377A 5589607 YP_001463278.1 CDS EcE24377A_2210 NC_009801.1 2176281 2177921 R hypothetical protein complement(2176281..2177921) Escherichia coli E24377A 5588213 YP_001463279.1 CDS EcE24377A_2211 NC_009801.1 2178030 2178311 R identified by similarity to GB:AAG04013.1; hypothetical protein complement(2178030..2178311) Escherichia coli E24377A 5589491 YP_001463280.1 CDS EcE24377A_2212 NC_009801.1 2178324 2178836 R hypothetical protein complement(2178324..2178836) Escherichia coli E24377A 5590404 YP_001463281.1 CDS EcE24377A_2213 NC_009801.1 2178854 2180359 R identified by similarity to SP:P22501; match to protein family HMM PF04984; major tail sheath protein complement(2178854..2180359) Escherichia coli E24377A 5588472 YP_001463282.1 CDS EcE24377A_2214 NC_009801.1 2180371 2181519 R identified by glimmer; hypothetical protein complement(2180371..2181519) Escherichia coli E24377A 5588034 YP_001463283.1 CDS EcE24377A_2215 NC_009801.1 2181512 2182138 R identified by match to protein family HMM TIGR01634; phage tail protein I complement(2181512..2182138) Escherichia coli E24377A 5589072 YP_001463284.1 CDS EcE24377A_2216 NC_009801.1 2182141 2183031 R identified by similarity to SP:P51767; match to protein family HMM PF04865; baseplate assembly protein J complement(2182141..2183031) Escherichia coli E24377A 5586566 YP_001463285.1 CDS EcE24377A_2217 NC_009801.1 2183058 2183399 R identified by similarity to SP:P51768; match to protein family HMM PF04965; baseplate assembly protein W complement(2183058..2183399) Escherichia coli E24377A 5590782 YP_001463286.1 CDS EcE24377A_2218 NC_009801.1 2183402 2184307 R identified by similarity to SP:P31340; match to protein family HMM PF04717; match to protein family HMM TIGR01644; phage baseplate assembly protein V complement(2183402..2184307) Escherichia coli E24377A 5586194 YP_001463287.1 CDS EcE24377A_2219 NC_009801.1 2184288 2184824 R identified by glimmer; hypothetical protein complement(2184288..2184824) Escherichia coli E24377A 5586201 YP_001463288.1 CDS EcE24377A_2220 NC_009801.1 2184821 2185474 R identified by glimmer; hypothetical protein complement(2184821..2185474) Escherichia coli E24377A 5588090 YP_001463289.1 CDS EcE24377A_2221 NC_009801.1 2185533 2185913 R identified by glimmer; hypothetical protein complement(2185533..2185913) Escherichia coli E24377A 5587075 YP_001463290.1 CDS EcE24377A_2222 NC_009801.1 2185910 2186323 R identified by similarity to GB:AAC19046.1; hypothetical protein complement(2185910..2186323) Escherichia coli E24377A 5587306 YP_001463291.1 CDS EcE24377A_2223 NC_009801.1 2186358 2187392 R identified by match to protein family HMM PF03864; phage major capsid protein E complement(2186358..2187392) Escherichia coli E24377A 5589449 YP_001463292.1 CDS EcE24377A_2224 NC_009801.1 2187454 2187783 R identified by match to protein family HMM PF02924; bacteriophage lambda head decoration protein D complement(2187454..2187783) Escherichia coli E24377A 5587235 YP_001463293.1 CDS EcE24377A_2225 NC_009801.1 2187783 2189093 R identified by match to protein family HMM PF01343; S49 family peptidase complement(2187783..2189093) Escherichia coli E24377A 5587059 YP_001463294.1 CDS EcE24377A_2227 NC_009801.1 2190088 2190882 R identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein complement(2190088..2190882) Escherichia coli E24377A 5589310 YP_001463295.1 CDS EcE24377A_2228 NC_009801.1 2190882 2192054 R identified by similarity to SP:P15025; match to protein family HMM PF00665; IS21 family transposase complement(2190882..2192054) Escherichia coli E24377A 5590622 YP_001463296.1 CDS EcE24377A_2230 NC_009801.1 2193020 2194984 R identified by match to protein family HMM PF05876; phage terminase large subunit (GpA) complement(2193020..2194984) Escherichia coli E24377A 5589405 YP_001463297.1 CDS EcE24377A_2231 NC_009801.1 2196342 2196812 D identified by glimmer; hypothetical protein 2196342..2196812 Escherichia coli E24377A 5587891 YP_001463298.1 CDS EcE24377A_2232 NC_009801.1 2197435 2197914 R identified by match to protein family HMM TIGR02594; hypothetical protein complement(2197435..2197914) Escherichia coli E24377A 5586957 YP_001463299.1 CDS EcE24377A_2233 NC_009801.1 2198594 2199265 R identified by match to protein family HMM PF06323; phage antitermination protein Q complement(2198594..2199265) Escherichia coli E24377A 5590474 YP_001463300.1 CDS EcE24377A_2234 NC_009801.1 2199265 2199558 R identified by match to protein family HMM PF07102; hypothetical protein complement(2199265..2199558) Escherichia coli E24377A 5590370 YP_001463301.1 CDS EcE24377A_2235 NC_009801.1 2199555 2200151 R identified by similarity to GB:AAX66528.1; match to protein family HMM PF07105; hypothetical protein complement(2199555..2200151) Escherichia coli E24377A 5589841 YP_001463302.1 CDS EcE24377A_2236 NC_009801.1 2200560 2201201 R identified by glimmer; hypothetical protein complement(2200560..2201201) Escherichia coli E24377A 5589088 YP_001463303.1 CDS EcE24377A_2237 NC_009801.1 2201711 2202490 D identified by glimmer; hypothetical protein 2201711..2202490 Escherichia coli E24377A 5590849 YP_001463304.1 CDS EcE24377A_2238 NC_009801.1 2203954 2205333 R identified by glimmer; hypothetical protein complement(2203954..2205333) Escherichia coli E24377A 5588130 YP_001463305.1 CDS EcE24377A_2239 NC_009801.1 2205659 2206465 D identified by similarity to GB:AAX67604.1; hypothetical protein 2205659..2206465 Escherichia coli E24377A 5590504 YP_001463306.1 CDS EcE24377A_2240 NC_009801.1 2206431 2206544 D identified by glimmer; hypothetical protein 2206431..2206544 Escherichia coli E24377A 5587505 YP_001463307.1 CDS EcE24377A_2241 NC_009801.1 2206546 2207781 D identified by glimmer; hypothetical protein 2206546..2207781 Escherichia coli E24377A 5589416 YP_001463308.1 CDS EcE24377A_2242 NC_009801.1 2207913 2208473 D lipoprotein 2207913..2208473 Escherichia coli E24377A 5588513 YP_001463309.1 CDS EcE24377A_2243 NC_009801.1 2208926 2209849 D lipoprotein 2208926..2209849 Escherichia coli E24377A 5587090 YP_001463310.1 CDS EcE24377A_2244 NC_009801.1 2210027 2210821 R hypothetical protein complement(2210027..2210821) Escherichia coli E24377A 5586270 YP_001463311.1 CDS EcE24377A_2245 NC_009801.1 2211503 2211727 R identified by glimmer; hypothetical protein complement(2211503..2211727) Escherichia coli E24377A 5590878 YP_001463312.1 CDS EcE24377A_2246 NC_009801.1 2211724 2211957 R identified by glimmer; hypothetical protein complement(2211724..2211957) Escherichia coli E24377A 5587914 YP_001463313.1 CDS EcE24377A_2247 NC_009801.1 2211957 2212358 R identified by similarity to GB:AAT84997.1; hypothetical protein complement(2211957..2212358) Escherichia coli E24377A 5590807 YP_001463314.1 CDS EcE24377A_2248 NC_009801.1 2212397 2213788 R identified by match to protein family HMM PF03796; DnaB family helicase complement(2212397..2213788) Escherichia coli E24377A 5587175 YP_001463315.1 CDS EcE24377A_2249 NC_009801.1 2213785 2214849 R hypothetical protein complement(2213785..2214849) Escherichia coli E24377A 5586330 YP_001463316.1 CDS EcE24377A_2250 NC_009801.1 2214852 2215076 R identified by similarity to GB:CAE15847.1; hypothetical protein complement(2214852..2215076) Escherichia coli E24377A 5590297 YP_001463317.1 CDS EcE24377A_2251 NC_009801.1 2215116 2215592 R identified by similarity to GB:CAE15848.1; match to protein family HMM PF06254; hypothetical protein complement(2215116..2215592) Escherichia coli E24377A 5587352 YP_001463318.1 CDS EcE24377A_2252 NC_009801.1 2215936 2216331 D The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown.; transcriptional repressor DicA 2215936..2216331 Escherichia coli E24377A 5590652 YP_001463319.1 CDS EcE24377A_2253 NC_009801.1 2216941 2219007 D identified by glimmer; hypothetical protein 2216941..2219007 Escherichia coli E24377A 5589277 YP_001463320.1 CDS EcE24377A_2254 NC_009801.1 2219004 2219573 D identified by similarity to GB:CAE15856.1; hypothetical protein 2219004..2219573 Escherichia coli E24377A 5589694 YP_001463321.1 CDS EcE24377A_2255 NC_009801.1 2219573 2219755 D identified by glimmer; hypothetical protein 2219573..2219755 Escherichia coli E24377A 5590545 YP_001463322.1 CDS EcE24377A_2256 NC_009801.1 2219965 2220180 D identified by similarity to GB:AAN69513.1; hypothetical protein 2219965..2220180 Escherichia coli E24377A 5589545 YP_001463323.1 CDS EcE24377A_2257 NC_009801.1 2220180 2221208 D identified by match to protein family HMM PF00589; phage integrase site specific recombinase 2220180..2221208 Escherichia coli E24377A 5586162 YP_001463324.1 CDS EcE24377A_2259 NC_009801.1 2221477 2222274 D identified by similarity to SP:P76346; match to protein family HMM PF06167; hypothetical protein 2221477..2222274 Escherichia coli E24377A 5587354 YP_001463325.1 CDS EcE24377A_2261 NC_009801.1 2222950 2229840 D identified by similarity to SP:P11922; match to protein family HMM PF00801; match to protein family HMM PF02369; invasin 2222950..2229840 Escherichia coli E24377A 5588891 YP_001463326.1 CDS EcE24377A_2262 NC_009801.1 2230102 2231154 R hypothetical protein complement(2230102..2231154) Escherichia coli E24377A 5587977 YP_001463327.1 CDS shiA NC_009801.1 2231469 2232785 D identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883; shikimate transporter 2231469..2232785 Escherichia coli E24377A 5585967 YP_001463328.1 CDS amn NC_009801.1 2232887 2234341 D Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2232887..2234341 Escherichia coli E24377A 5585924 YP_001463329.1 CDS EcE24377A_2265 NC_009801.1 2234684 2235400 D identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 2234684..2235400 Escherichia coli E24377A 5587332 YP_001463330.1 CDS EcE24377A_2267 NC_009801.1 2236030 2237670 R identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; hypothetical protein complement(2236030..2237670) Escherichia coli E24377A 5588875 YP_001463331.1 CDS cbl NC_009801.1 2237791 2238741 R LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl complement(2237791..2238741) Escherichia coli E24377A 5586049 YP_001463332.1 CDS nac NC_009801.1 2238843 2239760 R Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator complement(2238843..2239760) Escherichia coli E24377A 5590859 YP_001463333.1 CDS EcE24377A_2272 NC_009801.1 2240218 2241150 R identified by match to protein family HMM PF03734; hypothetical protein complement(2240218..2241150) Escherichia coli E24377A 5588874 YP_001463334.1 CDS cobT NC_009801.1 2241215 2242294 R catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase complement(2241215..2242294) Escherichia coli E24377A 5589336 YP_001463335.1 CDS cobS NC_009801.1 2242306 2243049 R catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase complement(2242306..2243049) Escherichia coli E24377A 5586672 YP_001463336.1 CDS cobU NC_009801.1 2243046 2243591 R catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase complement(2243046..2243591) Escherichia coli E24377A 5589573 YP_001463337.1 CDS EcE24377A_2276 NC_009801.1 2243725 2244162 R identified by similarity to SP:Q05631; cobalamin biosynthesis family protein complement(2243725..2244162) Escherichia coli E24377A 5588269 YP_001463338.1 CDS pocR NC_009801.1 2244644 2245558 R identified by similarity to SP:Q05587; match to protein family HMM PF00165; regulatory protein PocR complement(2244644..2245558) Escherichia coli E24377A 5588552 YP_001463339.1 CDS pduF NC_009801.1 2245761 2246570 R identified by similarity to SP:P37451; match to protein family HMM PF00230; match to protein family HMM TIGR00861; propanediol diffusion facilitator complement(2245761..2246570) Escherichia coli E24377A 5590844 YP_001463340.1 CDS pduA NC_009801.1 2247082 2247366 D identified by similarity to SP:P0A1C7; match to protein family HMM PF00936; propanediol utilization protein PduA 2247082..2247366 Escherichia coli E24377A 5586496 YP_001463341.1 CDS pduB NC_009801.1 2247474 2248175 D identified by similarity to SP:P37449; match to protein family HMM PF00936; propanediol utilization protein PduB 2247474..2248175 Escherichia coli E24377A 5587756 YP_001463342.1 CDS pduC NC_009801.1 2248194 2249858 D identified by similarity to SP:P37450; match to protein family HMM PF02286; propanediol utilization dehydratase, large subunit 2248194..2249858 Escherichia coli E24377A 5587739 YP_001463343.1 CDS pduD NC_009801.1 2249868 2250536 D identified by similarity to GB:AAB84103.1; match to protein family HMM PF02288; propanediol utilization dehydratase, medium subunit 2249868..2250536 Escherichia coli E24377A 5586673 YP_001463344.1 CDS pduE NC_009801.1 2250551 2251069 D identified by similarity to GB:AAB84104.1; match to protein family HMM PF02287; propanediol utilization dehydratase, small subunit 2250551..2251069 Escherichia coli E24377A 5586833 YP_001463345.1 CDS pduG NC_009801.1 2251079 2252911 D identified by similarity to GB:AAB84105.2; match to protein family HMM PF08841; propanediol utilization diol dehydratase reactivation protein 2251079..2252911 Escherichia coli E24377A 5588222 YP_001463346.1 CDS pduJ NC_009801.1 2253271 2253546 D identified by similarity to GB:AAD39009.1; match to protein family HMM PF00936; propanediol utilization protein PduJ 2253271..2253546 Escherichia coli E24377A 5588144 YP_001463347.1 CDS pduK NC_009801.1 2253570 2253992 D identified by similarity to GB:AAD39010.1; match to protein family HMM PF00936; propanediol utilization protein PduK 2253570..2253992 Escherichia coli E24377A 5585977 YP_001463348.1 CDS pduL NC_009801.1 2253995 2254627 D identified by match to protein family HMM PF06130; propanediol utilization protein PduL 2253995..2254627 Escherichia coli E24377A 5588811 YP_001463349.1 CDS pduM NC_009801.1 2254624 2255115 D identified by similarity to GB:AAD39012.1; propanediol utilization protein PduM 2254624..2255115 Escherichia coli E24377A 5588255 YP_001463350.1 CDS pduN NC_009801.1 2255119 2255394 D identified by similarity to GB:AAD39013.1; match to protein family HMM PF03319; propanediol utilization protein PduN 2255119..2255394 Escherichia coli E24377A 5587233 YP_001463351.1 CDS pduO NC_009801.1 2255406 2256413 D identified by similarity to GB:AAD39014.1; match to protein family HMM PF01923; match to protein family HMM PF03928; match to protein family HMM TIGR00636; propanediol utilization protein, PduO 2255406..2256413 Escherichia coli E24377A 5585941 YP_001463352.1 CDS pduP NC_009801.1 2256410 2257795 D identified by similarity to GB:AAD39015.1; match to protein family HMM PF00171; propanediol utilization protein PduP 2256410..2257795 Escherichia coli E24377A 5590125 YP_001463353.1 CDS pduQ NC_009801.1 2257806 2258918 D identified by similarity to GB:AAD39016.1; match to protein family HMM PF00465; propanediol utilization protein PduQ 2257806..2258918 Escherichia coli E24377A 5586231 YP_001463354.1 CDS pduS NC_009801.1 2258915 2260258 D identified by similarity to GB:AAD39017.1; match to protein family HMM PF00037; match to protein family HMM PF01512; propanediol utilization protein PduS 2258915..2260258 Escherichia coli E24377A 5586332 YP_001463355.1 CDS pduT NC_009801.1 2260261 2260815 D identified by similarity to GB:AAV76807.1; match to protein family HMM PF00936; propanediol utilization protein PduT 2260261..2260815 Escherichia coli E24377A 5588886 YP_001463356.1 CDS pduU NC_009801.1 2260815 2261165 D identified by similarity to SP:P0A1D1; match to protein family HMM PF00936; propanediol utilization protein pduU 2260815..2261165 Escherichia coli E24377A 5587214 YP_001463357.1 CDS pduV NC_009801.1 2261170 2261613 D identified by similarity to SP:Q9XDM6; match to protein family HMM TIGR02528; propanediol utilization protein PduV 2261170..2261613 Escherichia coli E24377A 5588787 YP_001463358.1 CDS EcE24377A_2298 NC_009801.1 2261714 2262043 R identified by match to protein family HMM PF04363; hypothetical protein complement(2261714..2262043) Escherichia coli E24377A 5587879 YP_001463359.1 CDS EcE24377A_2299 NC_009801.1 2262215 2263273 R hypothetical protein complement(2262215..2263273) Escherichia coli E24377A 5587818 YP_001463360.1 CDS gyrI NC_009801.1 2263472 2263945 R identified by similarity to GB:1JYH_A; match to protein family HMM PF06445; DNA gyrase inhibitor complement(2263472..2263945) Escherichia coli E24377A 5590012 YP_001463361.1 CDS dacD NC_009801.1 2264064 2265230 R removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase complement(2264064..2265230) Escherichia coli E24377A 5588879 YP_001463362.1 CDS sbcB NC_009801.1 2265419 2266846 D Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2265419..2266846 Escherichia coli E24377A 5588345 YP_001463363.1 CDS EcE24377A_2303 NC_009801.1 2266889 2267116 R identified by match to protein family HMM PF01206; hypothetical protein complement(2266889..2267116) Escherichia coli E24377A 5588437 YP_001463364.1 CDS EcE24377A_2304 NC_009801.1 2267130 2268179 R identified by match to protein family HMM PF04143; hypothetical protein complement(2267130..2268179) Escherichia coli E24377A 5587948 YP_001463365.1 CDS yeeF NC_009801.1 2268367 2269725 R identified by match to protein family HMM PF00324; amino acid permease complement(2268367..2269725) Escherichia coli E24377A 5587398 YP_001463366.1 CDS EcE24377A_2306 NC_009801.1 2269992 2270921 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(2269992..2270921) Escherichia coli E24377A 5589664 YP_001463367.1 CDS EcE24377A_2307 NC_009801.1 2270967 2271791 R identified by match to protein family HMM PF01073; match to protein family HMM PF01370; NAD dependent epimerase/dehydratase complement(2270967..2271791) Escherichia coli E24377A 5590710 YP_001463368.1 CDS yoeB NC_009801.1 2271874 2272128 R identified by similarity to SP:P69349; match to protein family HMM PF06769; match to protein family HMM TIGR02116; toxin YoeB complement(2271874..2272128) Escherichia coli E24377A 5588250 YP_001463369.1 CDS yefM NC_009801.1 2272125 2272376 R Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM complement(2272125..2272376) Escherichia coli E24377A 5588467 YP_001463370.1 CDS hisG NC_009801.1 2272855 2273754 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2272855..2273754 Escherichia coli E24377A 5590174 YP_001463371.1 CDS hisD NC_009801.1 2273760 2275064 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2273760..2275064 Escherichia coli E24377A 5589215 YP_001463372.1 CDS hisC NC_009801.1 2275061 2276131 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2275061..2276131 Escherichia coli E24377A 5586045 YP_001463373.1 CDS hisB NC_009801.1 2276131 2277198 D catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2276131..2277198 Escherichia coli E24377A 5586479 YP_001463374.1 CDS hisH NC_009801.1 2277198 2277788 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2277198..2277788 Escherichia coli E24377A 5589951 YP_001463375.1 CDS hisA NC_009801.1 2277788 2278525 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2277788..2278525 Escherichia coli E24377A 5586927 YP_001463376.1 CDS hisF NC_009801.1 2278507 2279283 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2278507..2279283 Escherichia coli E24377A 5588376 YP_001463377.1 CDS hisIE NC_009801.1 2279277 2279888 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2279277..2279888 Escherichia coli E24377A 5588106 YP_001463378.1 CDS EcE24377A_2318 NC_009801.1 2279985 2281019 R identified by similarity to SP:P76372; match to protein family HMM PF02706; chain length determinant protein complement(2279985..2281019) Escherichia coli E24377A 5587485 YP_001463379.1 CDS ugd NC_009801.1 2281109 2282275 R identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026; UDP-glucose 6-dehydrogenase complement(2281109..2282275) Escherichia coli E24377A 5586037 YP_001463380.1 CDS gnd NC_009801.1 2282520 2283926 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(2282520..2283926) Escherichia coli E24377A 5587627 YP_001463381.1 CDS EcE24377A_2321 NC_009801.1 2284294 2285181 R hypothetical protein complement(2284294..2285181) Escherichia coli E24377A 5588011 YP_001463382.1 CDS EcE24377A_2322 NC_009801.1 2285178 2286419 R hypothetical protein complement(2285178..2286419) Escherichia coli E24377A 5588319 YP_001463383.1 CDS EcE24377A_2323 NC_009801.1 2286419 2287171 R identified by glimmer; hypothetical protein complement(2286419..2287171) Escherichia coli E24377A 5586307 YP_001463384.1 CDS vipB NC_009801.1 2287268 2288299 R identified by similarity to SP:Q04973; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993; VI polysaccharide biosynthesis protein vipB/tviC complement(2287268..2288299) Escherichia coli E24377A 5588814 YP_001463385.1 CDS vipA NC_009801.1 2288314 2289588 R identified by similarity to SP:Q04972; match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026; VI polysaccharide biosynthesis protein VipA/tviB complement(2288314..2289588) Escherichia coli E24377A 5588346 YP_001463386.1 CDS EcE24377A_2326 NC_009801.1 2289707 2290720 R hypothetical protein complement(2289707..2290720) Escherichia coli E24377A 5588000 YP_001463387.1 CDS EcE24377A_2327 NC_009801.1 2290736 2291479 R glycosyl transferase family protein complement(2290736..2291479) Escherichia coli E24377A 5587227 YP_001463388.1 CDS EcE24377A_2328 NC_009801.1 2291476 2292456 R identified by match to protein family HMM PF00535; glycosyl transferase group 2 family protein complement(2291476..2292456) Escherichia coli E24377A 5588657 YP_001463389.1 CDS rfbC NC_009801.1 2292512 2293060 R identified by match to protein family HMM PF00908; match to protein family HMM TIGR01221; dTDP-4-dehydrorhamnose 3,5-epimerase complement(2292512..2293060) Escherichia coli E24377A 5588704 YP_001463390.1 CDS rfbA1 NC_009801.1 2293065 2293943 R identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidylyltransferase complement(2293065..2293943) Escherichia coli E24377A 5586178 YP_001463391.1 CDS rfbD NC_009801.1 2294001 2294900 R with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose; dTDP-4-dehydrorhamnose reductase complement(2294001..2294900) Escherichia coli E24377A 5590247 YP_001463392.1 CDS rfbB2 NC_009801.1 2294900 2295985 R NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose; dTDP-glucose-4,6-dehydratase complement(2294900..2295985) Escherichia coli E24377A 5589549 YP_001463393.1 CDS EcE24377A_2333 NC_009801.1 2296214 2296309 R identified by glimmer; hypothetical protein complement(2296214..2296309) Escherichia coli E24377A 5589629 YP_001463394.1 CDS galF NC_009801.1 2296357 2297250 R together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase complement(2296357..2297250) Escherichia coli E24377A 5589189 YP_001463395.1 CDS wcaM NC_009801.1 2297425 2298819 R WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein complement(2297425..2298819) Escherichia coli E24377A 5587086 YP_001463396.1 CDS wcaL NC_009801.1 2298830 2300050 R identified by match to protein family HMM PF00534; colanic acid biosynthesis glycosyl transferase WcaL complement(2298830..2300050) Escherichia coli E24377A 5588258 YP_001463397.1 CDS wcaK NC_009801.1 2300047 2301327 R identified by match to protein family HMM PF04230; pyruvyl transferase complement(2300047..2301327) Escherichia coli E24377A 5589091 YP_001463398.1 CDS wzxC NC_009801.1 2301603 2303081 R identified by match to protein family HMM PF01943; colanic acid exporter complement(2301603..2303081) Escherichia coli E24377A 5586801 YP_001463399.1 CDS EcE24377A_2339 NC_009801.1 2303083 2304477 R WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase complement(2303083..2304477) Escherichia coli E24377A 5589448 YP_001463400.1 CDS EcE24377A_2340 NC_009801.1 2304532 2305902 R identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphomannomutase complement(2304532..2305902) Escherichia coli E24377A 5590614 YP_001463401.1 CDS EcE24377A_2341 NC_009801.1 2305928 2306086 D identified by similarity to GB:AAN81029.1; hypothetical protein 2305928..2306086 Escherichia coli E24377A 5588765 YP_001463402.1 CDS manC NC_009801.1 2306095 2307531 R identified by similarity to SP:P24174; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; mannose-1-phosphate guanylyltransferase complement(2306095..2307531) Escherichia coli E24377A 5588393 YP_001463403.1 CDS wcaI NC_009801.1 2307534 2308757 R identified by match to protein family HMM PF00534; glycosyl transferase family protein complement(2307534..2308757) Escherichia coli E24377A 5590874 YP_001463404.1 CDS nudD NC_009801.1 2308754 2309233 R identified by similarity to SP:P32056; match to protein family HMM PF00293; GDP-mannose mannosyl hydrolase complement(2308754..2309233) Escherichia coli E24377A 5587808 YP_001463405.1 CDS fcl NC_009801.1 2309236 2310201 R identified by match to protein family HMM PF01370; match to protein family HMM PF04321; GDP-L-fucose synthetase complement(2309236..2310201) Escherichia coli E24377A 5587395 YP_001463406.1 CDS gmd NC_009801.1 2310204 2311325 R identified by match to protein family HMM PF01370; match to protein family HMM TIGR01472; GDP-mannose 4,6-dehydratase complement(2310204..2311325) Escherichia coli E24377A 5586851 YP_001463407.1 CDS EcE24377A_2347 NC_009801.1 2311351 2311899 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF complement(2311351..2311899) Escherichia coli E24377A 5586110 YP_001463408.1 CDS wcaE NC_009801.1 2311915 2312670 R identified by match to protein family HMM PF00535; glycosyl transferase family protein complement(2311915..2312670) Escherichia coli E24377A 5589707 YP_001463409.1 CDS wcaD NC_009801.1 2312681 2313898 R essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein complement(2312681..2313898) Escherichia coli E24377A 5587126 YP_001463410.1 CDS wcaC NC_009801.1 2313873 2315090 R glycosyl transferase family protein complement(2313873..2315090) Escherichia coli E24377A 5587427 YP_001463411.1 CDS EcE24377A_2351 NC_009801.1 2315087 2315575 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB complement(2315087..2315575) Escherichia coli E24377A 5590285 YP_001463412.1 CDS wcaA NC_009801.1 2315578 2316417 R identified by match to protein family HMM PF00535; glycosyl transferase family protein complement(2315578..2316417) Escherichia coli E24377A 5588480 YP_001463413.1 CDS wzc NC_009801.1 2316595 2318757 R Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase complement(2316595..2318757) Escherichia coli E24377A 5589348 YP_001463414.1 CDS wzb NC_009801.1 2318760 2319203 R Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase complement(2318760..2319203) Escherichia coli E24377A 5587936 YP_001463415.1 CDS EcE24377A_2355 NC_009801.1 2319209 2320348 R identified by match to protein family HMM PF02563; polysaccharide biosynthesis/export protein complement(2319209..2320348) Escherichia coli E24377A 5587272 YP_001463416.1 CDS EcE24377A_2356 NC_009801.1 2321007 2322590 D identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741; TerC family/CBS/transporter associated domain-containing protein 2321007..2322590 Escherichia coli E24377A 5589502 YP_001463417.1 CDS asmA NC_009801.1 2322864 2324717 R YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein complement(2322864..2324717) Escherichia coli E24377A 5586372 YP_001463418.1 CDS dcd NC_009801.1 2324739 2325320 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(2324739..2325320) Escherichia coli E24377A 5586633 YP_001463419.1 CDS udk NC_009801.1 2325412 2326053 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(2325412..2326053) Escherichia coli E24377A 5587552 YP_001463420.1 CDS EcE24377A_2360 NC_009801.1 2326371 2329688 D contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; sensor protein 2326371..2329688 Escherichia coli E24377A 5590152 YP_001463421.1 CDS alkA NC_009801.1 2329727 2330584 R inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase complement(2329727..2330584) Escherichia coli E24377A 5590068 YP_001463422.1 CDS EcE24377A_2362 NC_009801.1 2330718 2332070 D chaperone 2330718..2332070 Escherichia coli E24377A 5588627 YP_001463423.1 CDS EcE24377A_2363 NC_009801.1 2332082 2334022 R hypothetical protein complement(2332082..2334022) Escherichia coli E24377A 5586046 YP_001463424.1 CDS EcE24377A_2364 NC_009801.1 2334019 2334780 R identified by similarity to GB:AAP17498.1; hypothetical protein complement(2334019..2334780) Escherichia coli E24377A 5586243 YP_001463425.1 CDS EcE24377A_2365 NC_009801.1 2334777 2335436 R identified by match to protein family HMM PF00092; von Willebrand factor A complement(2334777..2335436) Escherichia coli E24377A 5590105 YP_001463426.1 CDS mdtA NC_009801.1 2336652 2337899 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2336652..2337899 Escherichia coli E24377A 5587477 YP_001463427.1 CDS mdtB NC_009801.1 2337899 2341021 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2337899..2341021 Escherichia coli E24377A 5590006 YP_001463428.1 CDS mdtC NC_009801.1 2341022 2344099 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2341022..2344099 Escherichia coli E24377A 5587177 YP_001463429.1 CDS EcE24377A_2369 NC_009801.1 2344100 2345515 D identified by match to protein family HMM PF07690; multidrug efflux system protein MdtE 2344100..2345515 Escherichia coli E24377A 5590634 YP_001463430.1 CDS baeS NC_009801.1 2345512 2346915 D identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; signal transduction histidine-protein kinase BaeS 2345512..2346915 Escherichia coli E24377A 5589156 YP_001463431.1 CDS baeR NC_009801.1 2346912 2347634 D response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2346912..2347634 Escherichia coli E24377A 5585970 YP_001463432.1 CDS EcE24377A_2372 NC_009801.1 2347825 2348157 D identified by similarity to SP:Q8EAL4; similarity to GB:CAG67631.1; match to protein family HMM PF07411; hypothetical protein 2347825..2348157 Escherichia coli E24377A 5588843 YP_001463433.1 CDS EcE24377A_2373 NC_009801.1 2348366 2348662 D identified by match to protein family HMM PF01402; match to protein family HMM PF03693; match to protein family HMM TIGR02606; CC2985 family addiction module antidote protein 2348366..2348662 Escherichia coli E24377A 5586626 YP_001463434.1 CDS EcE24377A_2374 NC_009801.1 2348664 2348960 D identified by match to protein family HMM PF05016; RelE/ParE family plasmid stabilization system protein 2348664..2348960 Escherichia coli E24377A 5586374 YP_001463435.1 CDS EcE24377A_2375 NC_009801.1 2349063 2350424 D identified by match to protein family HMM PF01136; U32 family peptidase 2349063..2350424 Escherichia coli E24377A 5589262 YP_001463436.1 CDS EcE24377A_2376 NC_009801.1 2350754 2351131 R identified by similarity to GB:ABB65576.1; hypothetical protein complement(2350754..2351131) Escherichia coli E24377A 5590776 YP_001463437.1 CDS EcE24377A_2377 NC_009801.1 2351477 2352376 D cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2351477..2352376 Escherichia coli E24377A 5586923 YP_001463438.1 CDS gatR NC_009801.1 2352458 2353231 R identified by similarity to SP:P36930; match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; galactitol utilization operon repressor complement(2352458..2353231) Escherichia coli E24377A 5588849 YP_001463439.1 CDS gatD NC_009801.1 2353337 2354377 R Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase complement(2353337..2354377) Escherichia coli E24377A 5588829 YP_001463440.1 CDS gatC NC_009801.1 2354425 2355780 R identified by match to protein family HMM PF03611; match to protein family HMM TIGR00827; PTS system galactitol-specific transporter subunit IIC complement(2354425..2355780) Escherichia coli E24377A 5587011 YP_001463441.1 CDS gatB NC_009801.1 2355784 2356068 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB complement(2355784..2356068) Escherichia coli E24377A 5589107 YP_001463442.1 CDS gatA NC_009801.1 2356099 2356551 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA complement(2356099..2356551) Escherichia coli E24377A 5587605 YP_001463443.1 CDS EcE24377A_2383 NC_009801.1 2356561 2357823 R identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810; D-tagatose-bisphosphate aldolase non-catalytic subunit complement(2356561..2357823) Escherichia coli E24377A 5589435 YP_001463444.1 CDS gatY NC_009801.1 2357852 2358706 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(2357852..2358706) Escherichia coli E24377A 5587419 YP_001463445.1 CDS fbaB NC_009801.1 2359014 2360066 R catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase complement(2359014..2360066) Escherichia coli E24377A 5586555 YP_001463446.1 CDS yegT NC_009801.1 2360323 2361600 D identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889; nucleoside transporter 2360323..2361600 Escherichia coli E24377A 5590547 YP_001463447.1 CDS EcE24377A_2387 NC_009801.1 2361597 2362601 D identified by match to protein family HMM PF03747; ADP-ribosylglycohydrolase 2361597..2362601 Escherichia coli E24377A 5590009 YP_001463448.1 CDS EcE24377A_2389 NC_009801.1 2362598 2363563 D identified by match to protein family HMM PF00294; PfkB family kinase 2362598..2363563 Escherichia coli E24377A 5586101 YP_001463449.1 CDS EcE24377A_2388 NC_009801.1 2363537 2364283 R identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM PF08279; GntR family transcriptional regulator complement(2363537..2364283) Escherichia coli E24377A 5586569 YP_001463450.1 CDS EcE24377A_2390 NC_009801.1 2364335 2365153 R identified by match to protein family HMM PF01183; glycosyl hydrolase complement(2364335..2365153) Escherichia coli E24377A 5587983 YP_001463451.1 CDS thiD NC_009801.1 2365218 2366018 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(2365218..2366018) Escherichia coli E24377A 5586968 YP_001463452.1 CDS thiM NC_009801.1 2366015 2366803 R catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase complement(2366015..2366803) Escherichia coli E24377A 5590734 YP_001463453.1 CDS rcnR NC_009801.1 2367026 2367298 R identified by similarity to SP:P64530; match to protein family HMM PF02583; transcriptional repressor RcnR complement(2367026..2367298) Escherichia coli E24377A 5589199 YP_001463454.1 CDS EcE24377A_2395 NC_009801.1 2368282 2368800 D identified by similarity to GB:AAN81090.1; hypothetical protein 2368282..2368800 Escherichia coli E24377A 5586583 YP_001463455.1 CDS EcE24377A_2396 NC_009801.1 2368882 2369916 R hypothetical protein complement(2368882..2369916) Escherichia coli E24377A 5590377 YP_001463456.1 CDS EcE24377A_2397 NC_009801.1 2369435 2369599 D identified by glimmer; hypothetical protein 2369435..2369599 Escherichia coli E24377A 5590342 YP_001463457.1 CDS EcE24377A_2399 NC_009801.1 2369930 2372410 R identified by match to protein family HMM PF00577; fimbrial usher protein complement(2369930..2372410) Escherichia coli E24377A 5589063 YP_001463458.1 CDS EcE24377A_2400 NC_009801.1 2372426 2373100 R identified by match to protein family HMM PF00345; match to protein family HMM PF02753; pilus assembly chaperone complement(2372426..2373100) Escherichia coli E24377A 5590777 YP_001463459.1 CDS EcE24377A_2401 NC_009801.1 2372793 2372903 D identified by glimmer; hypothetical protein 2372793..2372903 Escherichia coli E24377A 5590599 YP_001463460.1 CDS EcE24377A_2402 NC_009801.1 2373181 2373723 R identified by match to protein family HMM PF00419; fimbrial protein complement(2373181..2373723) Escherichia coli E24377A 5586693 YP_001463461.1 CDS EcE24377A_2403 NC_009801.1 2374560 2375669 R identified by similarity to SP:P0AF08; ATPase complement(2374560..2375669) Escherichia coli E24377A 5586205 YP_001463462.1 CDS metG NC_009801.1 2375801 2377834 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2375801..2377834 Escherichia coli E24377A 5588091 YP_001463463.1 CDS molR NC_009801.1 2377975 2381769 D identified by similarity to SP:P33345; match to protein family HMM PF05406; molybdate metabolism regulator 2377975..2381769 Escherichia coli E24377A 5590235 YP_001463464.1 CDS EcE24377A_2407 NC_009801.1 2386975 2388063 D identified by match to protein family HMM PF07728; ATPase AAA 2386975..2388063 Escherichia coli E24377A 5590354 YP_001463465.1 CDS EcE24377A_2408 NC_009801.1 2388074 2390353 D identified by similarity to GB:AAN81106.1; hypothetical protein 2388074..2390353 Escherichia coli E24377A 5588981 YP_001463466.1 CDS EcE24377A_2409 NC_009801.1 2390346 2391482 D yehP; identified by match to protein family HMM PF05762; von Willebrand factor A 2390346..2391482 Escherichia coli E24377A 5590273 YP_001463467.1 CDS EcE24377A_2410 NC_009801.1 2391479 2393479 D identified by match to protein family HMM PF04434; hypothetical protein 2391479..2393479 Escherichia coli E24377A 5590516 YP_001463468.1 CDS EcE24377A_2411 NC_009801.1 2393604 2394065 D identified by match to protein family HMM PF06998; lipoprotein 2393604..2394065 Escherichia coli E24377A 5590589 YP_001463469.1 CDS EcE24377A_2412 NC_009801.1 2394106 2394576 R identified by match to protein family HMM PF07308; hypothetical protein complement(2394106..2394576) Escherichia coli E24377A 5590362 YP_001463470.1 CDS EcE24377A_2413 NC_009801.1 2394623 2395342 R unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT complement(2394623..2395342) Escherichia coli E24377A 5587067 YP_001463471.1 CDS EcE24377A_2414 NC_009801.1 2395339 2397024 R identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694; sensor histidine kinase complement(2395339..2397024) Escherichia coli E24377A 5590880 YP_001463472.1 CDS mlrA NC_009801.1 2397246 2397977 D identified by similarity to SP:P33358; match to protein family HMM PF00376; transcriptional regulator MlrA 2397246..2397977 Escherichia coli E24377A 5587196 YP_001463473.1 CDS EcE24377A_2417 NC_009801.1 2398037 2398144 D identified by similarity to GB:AAZ88835.1; hypothetical protein 2398037..2398144 Escherichia coli E24377A 5586753 YP_001463474.1 CDS EcE24377A_2416 NC_009801.1 2398125 2398856 R identified by match to protein family HMM PF00528; quaternary amine ABC transporter permease complement(2398125..2398856) Escherichia coli E24377A 5586039 YP_001463475.1 CDS EcE24377A_2418 NC_009801.1 2398861 2399787 R identified by match to protein family HMM PF00005; quaternary amine ABC transporter ATP-binding protein complement(2398861..2399787) Escherichia coli E24377A 5587114 YP_001463476.1 CDS EcE24377A_2419 NC_009801.1 2399780 2400937 R identified by match to protein family HMM PF00528; quaternary amine ABC transporter permease complement(2399780..2400937) Escherichia coli E24377A 5589601 YP_001463477.1 CDS EcE24377A_2420 NC_009801.1 2400944 2401861 R identified by match to protein family HMM PF04069; quaternary amine ABC transporter substrate-binding protein complement(2400944..2401861) Escherichia coli E24377A 5588670 YP_001463478.1 CDS bglX NC_009801.1 2402113 2404410 R identified by similarity to SP:P33363; match to protein family HMM PF00933; match to protein family HMM PF01915; beta-glucosidase, periplasmic complement(2402113..2404410) Escherichia coli E24377A 5590165 YP_001463479.1 CDS EcE24377A_2422 NC_009801.1 2404411 2404569 D identified by glimmer; hypothetical protein 2404411..2404569 Escherichia coli E24377A 5588330 YP_001463480.1 CDS dld NC_009801.1 2404606 2406321 D component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2404606..2406321 Escherichia coli E24377A 5588735 YP_001463481.1 CDS pbpG NC_009801.1 2406359 2407300 R specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase complement(2406359..2407300) Escherichia coli E24377A 5587460 YP_001463482.1 CDS EcE24377A_2425 NC_009801.1 2407465 2408052 R identified by match to protein family HMM PF06930; hypothetical protein complement(2407465..2408052) Escherichia coli E24377A 5590060 YP_001463483.1 CDS EcE24377A_2426 NC_009801.1 2408222 2408800 D identified by similarity to SP:P33366; match to protein family HMM PF09335; hypothetical protein 2408222..2408800 Escherichia coli E24377A 5586263 YP_001463484.1 CDS EcE24377A_2427 NC_009801.1 2408930 2409691 R identified by match to protein family HMM PF00106; acetoin dehydrogenase complement(2408930..2409691) Escherichia coli E24377A 5588455 YP_001463485.1 CDS EcE24377A_2428 NC_009801.1 2409744 2411180 R may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ complement(2409744..2411180) Escherichia coli E24377A 5589555 YP_001463486.1 CDS dusC NC_009801.1 2411860 2412807 R identified by similarity to SP:P33371; match to protein family HMM PF01207; tRNA-dihydrouridine synthase C complement(2411860..2412807) Escherichia coli E24377A 5590349 YP_001463487.1 CDS maiA NC_009801.1 2414076 2414720 R identified by match to protein family HMM PF02798; match to protein family HMM TIGR01262; maleylacetoacetate isomerase complement(2414076..2414720) Escherichia coli E24377A 5590059 YP_001463488.1 CDS EcE24377A_2432 NC_009801.1 2414729 2415430 R identified by match to protein family HMM PF01557; fumarylacetoacetate hydrolase complement(2414729..2415430) Escherichia coli E24377A 5586070 YP_001463489.1 CDS gtdA NC_009801.1 2415446 2416474 R identified by similarity to GB:CAA12267.1; match to protein family HMM PF07883; match to protein family HMM TIGR02272; gentisate 1,2-dioxygenase complement(2415446..2416474) Escherichia coli E24377A 5590259 YP_001463490.1 CDS EcE24377A_2434 NC_009801.1 2416486 2417844 R identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator transporter complement(2416486..2417844) Escherichia coli E24377A 5589206 YP_001463491.1 CDS EcE24377A_2435 NC_009801.1 2417923 2418879 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2417923..2418879 Escherichia coli E24377A 5590519 YP_001463492.1 CDS EcE24377A_2436 NC_009801.1 2419010 2419408 D identified by match to protein family HMM PF03788; hypothetical protein 2419010..2419408 Escherichia coli E24377A 5586300 YP_001463493.1 CDS EcE24377A_2437 NC_009801.1 2419405 2420100 D identified by match to protein family HMM PF04172; match to protein family HMM TIGR00659; hypothetical protein 2419405..2420100 Escherichia coli E24377A 5586808 YP_001463494.1 CDS cdd NC_009801.1 2420230 2421114 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2420230..2421114 Escherichia coli E24377A 5585998 YP_001463495.1 CDS sanA NC_009801.1 2421264 2421983 D identified by similarity to SP:P0AFY5; match to protein family HMM PF02698; hypothetical protein 2421264..2421983 Escherichia coli E24377A 5587811 YP_001463496.1 CDS EcE24377A_2440 NC_009801.1 2421986 2422225 D identified by similarity to SP:P64539; hypothetical protein 2421986..2422225 Escherichia coli E24377A 5586711 YP_001463497.1 CDS EcE24377A_2441 NC_009801.1 2422544 2423782 D function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 2422544..2423782 Escherichia coli E24377A 5586014 YP_001463498.1 CDS EcE24377A_2442 NC_009801.1 2423776 2425011 D catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2423776..2425011 Escherichia coli E24377A 5590585 YP_001463499.1 CDS mglC NC_009801.1 2425082 2426092 R ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein complement(2425082..2426092) Escherichia coli E24377A 5589548 YP_001463500.1 CDS mglA NC_009801.1 2426108 2427628 R with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein complement(2426108..2427628) Escherichia coli E24377A 5589759 YP_001463501.1 CDS mglB NC_009801.1 2427689 2428687 R identified by similarity to SP:P0AEE5; match to protein family HMM PF00532; galactose ABC transporter periplasmic galactose-binding protein complement(2427689..2428687) Escherichia coli E24377A 5589862 YP_001463502.1 CDS galS NC_009801.1 2428967 2430007 R negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS complement(2428967..2430007) Escherichia coli E24377A 5586644 YP_001463503.1 CDS EcE24377A_2448 NC_009801.1 2429997 2430200 D identified by glimmer; hypothetical protein 2429997..2430200 Escherichia coli E24377A 5589470 YP_001463504.1 CDS EcE24377A_2447 NC_009801.1 2430149 2431306 R identified by match to protein family HMM PF04171; match to protein family HMM PF04235; hypothetical protein complement(2430149..2431306) Escherichia coli E24377A 5586992 YP_001463505.1 CDS folE NC_009801.1 2431323 2431991 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(2431323..2431991) Escherichia coli E24377A 5587776 YP_001463506.1 CDS fghA2 NC_009801.1 2432249 2433085 D identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821; S-formylglutathione hydrolase 2432249..2433085 Escherichia coli E24377A 5590639 YP_001463507.1 CDS cirA NC_009801.1 2433117 2435108 R Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor complement(2433117..2435108) Escherichia coli E24377A 5587524 YP_001463508.1 CDS EcE24377A_2452 NC_009801.1 2435101 2435304 R identified by glimmer; hypothetical protein complement(2435101..2435304) Escherichia coli E24377A 5586763 YP_001463509.1 CDS lysP NC_009801.1 2435401 2436870 R identified by match to protein family HMM PF00324; lysine transporter complement(2435401..2436870) Escherichia coli E24377A 5586468 YP_001463510.1 CDS EcE24377A_2454 NC_009801.1 2437075 2437956 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator complement(2437075..2437956) Escherichia coli E24377A 5588526 YP_001463511.1 CDS EcE24377A_2455 NC_009801.1 2438055 2439104 D identified by match to protein family HMM PF03601; match to protein family HMM TIGR00698; hypothetical protein 2438055..2439104 Escherichia coli E24377A 5590098 YP_001463512.1 CDS nfo NC_009801.1 2439178 2440035 D Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2439178..2440035 Escherichia coli E24377A 5589264 YP_001463513.1 CDS EcE24377A_2458 NC_009801.1 2441183 2442433 R identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804; NupC family nucleoside transporter complement(2441183..2442433) Escherichia coli E24377A 5588385 YP_001463514.1 CDS rihB NC_009801.1 2442533 2443474 R Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 complement(2442533..2443474) Escherichia coli E24377A 5586900 YP_001463515.1 CDS nsr NC_009801.1 2443643 2444302 D activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2443643..2444302 Escherichia coli E24377A 5588427 YP_001463516.1 CDS yeiM NC_009801.1 2444373 2445623 R identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804; NupC family nucleoside transporter complement(2444373..2445623) Escherichia coli E24377A 5587252 YP_001463517.1 CDS EcE24377A_2462 NC_009801.1 2445717 2446655 R identified by match to protein family HMM PF04227; indigoidine synthase A like protein complement(2445717..2446655) Escherichia coli E24377A 5587033 YP_001463518.1 CDS EcE24377A_2463 NC_009801.1 2446643 2447584 R identified by match to protein family HMM PF00294; hypothetical protein complement(2446643..2447584) Escherichia coli E24377A 5589969 YP_001463519.1 CDS fruA NC_009801.1 2448008 2449699 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC complement(2448008..2449699) Escherichia coli E24377A 5586727 YP_001463520.1 CDS fruK NC_009801.1 2449716 2450654 R converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase complement(2449716..2450654) Escherichia coli E24377A 5590063 YP_001463521.1 CDS fruB NC_009801.1 2450654 2451784 R phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein complement(2450654..2451784) Escherichia coli E24377A 5589819 YP_001463522.1 CDS EcE24377A_2467 NC_009801.1 2451950 2452081 D identified by glimmer; hypothetical protein 2451950..2452081 Escherichia coli E24377A 5588629 YP_001463523.1 CDS setB NC_009801.1 2452152 2453333 D identified by match to protein family HMM PF07690; match to protein family HMM TIGR00899; sugar efflux transporter B 2452152..2453333 Escherichia coli E24377A 5588835 YP_001463524.1 CDS EcE24377A_2469 NC_009801.1 2453484 2454311 D Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2453484..2454311 Escherichia coli E24377A 5586383 YP_001463525.1 CDS EcE24377A_2470 NC_009801.1 2454534 2456000 D identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol dehydrogenase 2454534..2456000 Escherichia coli E24377A 5586804 YP_001463526.1 CDS EcE24377A_2471 NC_009801.1 2456118 2457104 D identified by match to protein family HMM PF02492; match to protein family HMM PF07683; CobW/P47K family protein 2456118..2457104 Escherichia coli E24377A 5586413 YP_001463527.1 CDS EcE24377A_2472 NC_009801.1 2457143 2457856 D identified by match to protein family HMM PF01569; PAP2 family protein 2457143..2457856 Escherichia coli E24377A 5587469 YP_001463528.1 CDS spr NC_009801.1 2458268 2458834 D by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 2458268..2458834 Escherichia coli E24377A 5588397 YP_001463529.1 CDS EcE24377A_2474 NC_009801.1 2459015 2460571 D identified by similarity to SP:P76446; match to protein family HMM PF00563; hypothetical protein 2459015..2460571 Escherichia coli E24377A 5588297 YP_001463530.1 CDS EcE24377A_2475 NC_009801.1 2460653 2462467 D identified by match to protein family HMM PF00496; ABC transporter periplasmic solute-binding protein 2460653..2462467 Escherichia coli E24377A 5587442 YP_001463531.1 CDS EcE24377A_2476 NC_009801.1 2462468 2463562 D identified by match to protein family HMM PF00528; ABC transporter permease 2462468..2463562 Escherichia coli E24377A 5590651 YP_001463532.1 CDS EcE24377A_2477 NC_009801.1 2463562 2464587 D identified by match to protein family HMM PF00528; ABC transporter permease 2463562..2464587 Escherichia coli E24377A 5589152 YP_001463533.1 CDS EcE24377A_2478 NC_009801.1 2464589 2466178 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2464589..2466178 Escherichia coli E24377A 5589243 YP_001463534.1 CDS EcE24377A_2479 NC_009801.1 2466182 2466526 R identified by similarity to SP:P0AD23; hypothetical protein complement(2466182..2466526) Escherichia coli E24377A 5590065 YP_001463535.1 CDS bcr NC_009801.1 2466859 2468049 R Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein complement(2466859..2468049) Escherichia coli E24377A 5588600 YP_001463536.1 CDS rsuA NC_009801.1 2468077 2468772 R catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A complement(2468077..2468772) Escherichia coli E24377A 5589045 YP_001463537.1 CDS EcE24377A_2482 NC_009801.1 2468921 2470681 D identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851; helicase 2468921..2470681 Escherichia coli E24377A 5589781 YP_001463538.1 CDS rplY NC_009801.1 2470806 2471090 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2470806..2471090 Escherichia coli E24377A 5588838 YP_001463539.1 CDS ndpA NC_009801.1 2471229 2472236 R identified by similarity to SP:P33920; match to protein family HMM PF04245; nucleoid-associated protein NdpA complement(2471229..2472236) Escherichia coli E24377A 5587178 YP_001463540.1 CDS EcE24377A_2485 NC_009801.1 2472281 2472400 R identified by glimmer; hypothetical protein complement(2472281..2472400) Escherichia coli E24377A 5587342 YP_001463541.1 CDS EcE24377A_2486 NC_009801.1 2472418 2472645 D identified by match to protein family HMM PF07208; hypothetical protein 2472418..2472645 Escherichia coli E24377A 5589139 YP_001463542.1 CDS EcE24377A_2487 NC_009801.1 2472665 2474425 D identified by match to protein family HMM PF00884; sulfatase 2472665..2474425 Escherichia coli E24377A 5589803 YP_001463543.1 CDS EcE24377A_2491 NC_009801.1 2477387 2477482 D identified by glimmer; hypothetical protein 2477387..2477482 Escherichia coli E24377A 5590864 YP_001463544.1 CDS narP NC_009801.1 2477591 2478238 D nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2477591..2478238 Escherichia coli E24377A 5585914 YP_001463545.1 CDS EcE24377A_2493 NC_009801.1 2478273 2479325 R identified by match to protein family HMM PF03918; cytochrome c-type biogenesis family protein complement(2478273..2479325) Escherichia coli E24377A 5588966 YP_001463546.1 CDS dsbE NC_009801.1 2479322 2479879 R identified by similarity to SP:P0AA86; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR00385; thiol:disulfide interchange protein DsbE complement(2479322..2479879) Escherichia coli E24377A 5587530 YP_001463547.1 CDS ccmF NC_009801.1 2479876 2481819 R identified by match to protein family HMM PF01578; match to protein family HMM TIGR00353; cytochrome c-type biogenesis protein CcmF complement(2479876..2481819) Escherichia coli E24377A 5586013 YP_001463548.1 CDS ccmE NC_009801.1 2481816 2482295 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE complement(2481816..2482295) Escherichia coli E24377A 5586667 YP_001463549.1 CDS ccmD NC_009801.1 2482292 2482501 R identified by match to protein family HMM PF04995; match to protein family HMM TIGR03141; heme exporter protein D complement(2482292..2482501) Escherichia coli E24377A 5590785 YP_001463550.1 CDS ccmC NC_009801.1 2482498 2483235 R identified by match to protein family HMM PF01578; match to protein family HMM TIGR01191; heme exporter protein C complement(2482498..2483235) Escherichia coli E24377A 5587380 YP_001463551.1 CDS ccmB NC_009801.1 2483277 2483939 R identified by match to protein family HMM PF03379; match to protein family HMM TIGR01190; heme exporter protein CcmB complement(2483277..2483939) Escherichia coli E24377A 5589368 YP_001463552.1 CDS ccmA NC_009801.1 2483936 2484553 R ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA complement(2483936..2484553) Escherichia coli E24377A 5587127 YP_001463553.1 CDS napC NC_009801.1 2484572 2485174 R with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC complement(2484572..2485174) Escherichia coli E24377A 5588581 YP_001463554.1 CDS napB NC_009801.1 2485184 2485633 R small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit complement(2485184..2485633) Escherichia coli E24377A 5590317 YP_001463555.1 CDS napH NC_009801.1 2485630 2486493 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component complement(2485630..2486493) Escherichia coli E24377A 5586375 YP_001463556.1 CDS napG NC_009801.1 2486480 2487175 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component complement(2486480..2487175) Escherichia coli E24377A 5588432 YP_001463557.1 CDS napA NC_009801.1 2487182 2489668 R periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit complement(2487182..2489668) Escherichia coli E24377A 5586430 YP_001463558.1 CDS napD NC_009801.1 2489665 2489928 R identified by match to protein family HMM PF03927; assembly protein for periplasmic nitrate reductase complement(2489665..2489928) Escherichia coli E24377A 5587190 YP_001463559.1 CDS napF NC_009801.1 2489918 2490412 R Predicted role in electron transfer to the periplasmic nitrate reductase NapA.; ferredoxin-type protein complement(2489918..2490412) Escherichia coli E24377A 5585933 YP_001463560.1 CDS eco NC_009801.1 2490820 2491308 D serine protease inhibitor, inhibits trypsin and other proteases; ecotin 2490820..2491308 Escherichia coli E24377A 5586874 YP_001463561.1 CDS mqo NC_009801.1 2491457 2493103 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(2491457..2493103) Escherichia coli E24377A 5588173 YP_001463562.1 CDS EcE24377A_2510 NC_009801.1 2493321 2494964 R efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane protein/ATP-binding component complement(2493321..2494964) Escherichia coli E24377A 5586113 YP_001463563.1 CDS alkB NC_009801.1 2495040 2495690 R identified by similarity to SP:P05050; match to protein family HMM PF03171; match to protein family HMM TIGR00568; alkylated DNA repair protein AlkB complement(2495040..2495690) Escherichia coli E24377A 5589150 YP_001463564.1 CDS ada NC_009801.1 2495690 2496754 R identified by similarity to SP:P06134; match to protein family HMM PF00165; match to protein family HMM PF01035; match to protein family HMM PF02805; match to protein family HMM PF02870; match to protein family HMM TIGR00589; regulatory protein Ada complement(2495690..2496754) Escherichia coli E24377A 5586469 YP_001463565.1 CDS apbE NC_009801.1 2496828 2497883 R catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE complement(2496828..2497883) Escherichia coli E24377A 5588074 YP_001463566.1 CDS ompC NC_009801.1 2497995 2499086 R allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C complement(2497995..2499086) Escherichia coli E24377A 5587201 YP_001463567.1 CDS yojN NC_009801.1 2499825 2502497 D identified by match to protein family HMM PF01627; match to protein family HMM PF02518; phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2499825..2502497 Escherichia coli E24377A 5588055 YP_001463568.1 CDS rcsB NC_009801.1 2502514 2503164 D two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2502514..2503164 Escherichia coli E24377A 5587582 YP_001463569.1 CDS EcE24377A_2516 NC_009801.1 2503161 2503262 R identified by glimmer; hypothetical protein complement(2503161..2503262) Escherichia coli E24377A 5590740 YP_001463570.1 CDS EcE24377A_2518 NC_009801.1 2503193 2503288 D identified by glimmer; hypothetical protein 2503193..2503288 Escherichia coli E24377A 5587338 YP_001463571.1 CDS rcsC NC_009801.1 2503364 2506213 R identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518; hybrid sensory kinase in two-component regulatory system with RcsB and YojN complement(2503364..2506213) Escherichia coli E24377A 5586692 YP_001463572.1 CDS EcE24377A_2520 NC_009801.1 2506383 2506478 D identified by glimmer; hypothetical protein 2506383..2506478 Escherichia coli E24377A 5586662 YP_001463573.1 CDS EcE24377A_2521 NC_009801.1 2506488 2507264 R identified by similarity to GB:AAG07875.1; hypothetical protein complement(2506488..2507264) Escherichia coli E24377A 5586950 YP_001463574.1 CDS EcE24377A_2522 NC_009801.1 2507269 2508918 R identified by similarity to GB:AAZ88932.1; hypothetical protein complement(2507269..2508918) Escherichia coli E24377A 5589522 YP_001463575.1 CDS EcE24377A_2523 NC_009801.1 2508919 2513433 R identified by match to protein family HMM PF01835; match to protein family HMM PF07703; alpha-2-macroglobulin complement(2508919..2513433) Escherichia coli E24377A 5590239 YP_001463576.2 CDS EcE24377A_2524 NC_009801.1 2513457 2514080 R identified by match to protein family HMM PF06672; hypothetical protein complement(2513457..2514080) Escherichia coli E24377A 5589789 YP_001463577.1 CDS EcE24377A_2525 NC_009801.1 2514077 2515765 R identified by similarity to SP:P17994; hypothetical protein complement(2514077..2515765) Escherichia coli E24377A 5589940 YP_001463578.1 CDS gyrA NC_009801.1 2515914 2518541 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(2515914..2518541) Escherichia coli E24377A 5589602 YP_001463579.1 CDS ubiG NC_009801.1 2518688 2519410 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2518688..2519410 Escherichia coli E24377A 5587253 YP_001463580.1 CDS EcE24377A_2528 NC_009801.1 2519471 2523229 R yfaL; identified by match to protein family HMM PF02415; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01376; match to protein family HMM TIGR01414; match to protein family HMM TIGR02601; adhesin complement(2519471..2523229) Escherichia coli E24377A 5585919 YP_001463581.1 CDS EcE24377A_2529 NC_009801.1 2522981 2523079 D identified by glimmer; hypothetical protein 2522981..2523079 Escherichia coli E24377A 5589998 YP_001463582.1 CDS EcE24377A_2530 NC_009801.1 2523590 2523682 D identified by glimmer; hypothetical protein 2523590..2523682 Escherichia coli E24377A 5589444 YP_001463583.1 CDS nrdA NC_009801.1 2523925 2526210 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2523925..2526210 Escherichia coli E24377A 5587452 YP_001463584.1 CDS nrdB NC_009801.1 2526299 2527429 D B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2526299..2527429 Escherichia coli E24377A 5589922 YP_001463585.1 CDS EcE24377A_2533 NC_009801.1 2527429 2527683 D plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 2527429..2527683 Escherichia coli E24377A 5586251 YP_001463586.1 CDS inaA NC_009801.1 2527737 2528387 R identified by match to protein family HMM PF06293; hypothetical protein complement(2527737..2528387) Escherichia coli E24377A 5590118 YP_001463587.1 CDS EcE24377A_2535 NC_009801.1 2528602 2528808 D hypothetical protein 2528602..2528808 Escherichia coli E24377A 5586389 YP_001463588.1 CDS glpQ NC_009801.1 2528850 2529926 R hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase complement(2528850..2529926) Escherichia coli E24377A 5587706 YP_001463589.1 CDS glpT NC_009801.1 2529931 2531289 R catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter complement(2529931..2531289) Escherichia coli E24377A 5587723 YP_001463590.1 CDS EcE24377A_2538 NC_009801.1 2531340 2531537 D identified by glimmer; hypothetical protein 2531340..2531537 Escherichia coli E24377A 5588815 YP_001463591.1 CDS glpA NC_009801.1 2531562 2533190 D anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2531562..2533190 Escherichia coli E24377A 5590487 YP_001463592.1 CDS glpB NC_009801.1 2533180 2534439 D sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2533180..2534439 Escherichia coli E24377A 5586856 YP_001463593.1 CDS glpC NC_009801.1 2534436 2535626 D anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2534436..2535626 Escherichia coli E24377A 5586150 YP_001463594.1 CDS EcE24377A_2542 NC_009801.1 2535820 2536722 D identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein 2535820..2536722 Escherichia coli E24377A 5588847 YP_001463595.1 CDS EcE24377A_2543 NC_009801.1 2536763 2537275 R identified by match to protein family HMM PF03328; HpcH/HpaI aldolase/citrate lyase complement(2536763..2537275) Escherichia coli E24377A 5586079 YP_001463596.1 CDS EcE24377A_2544 NC_009801.1 2537288 2538490 R identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR00200; competence damage-inducible protein A complement(2537288..2538490) Escherichia coli E24377A 5588073 YP_001463597.1 CDS EcE24377A_2545 NC_009801.1 2538590 2539132 R identified by similarity to SP:P76471; match to protein family HMM PF07437; outer membrane protein, YfaZ complement(2538590..2539132) Escherichia coli E24377A 5590538 YP_001463598.1 CDS EcE24377A_2546 NC_009801.1 2539411 2539836 D identified by match to protein family HMM PF00293; NUDIX family hydrolase 2539411..2539836 Escherichia coli E24377A 5590356 YP_001463599.1 CDS EcE24377A_2547 NC_009801.1 2539875 2540477 R identified by match to protein family HMM PF00300; phosphoglycerate mutase complement(2539875..2540477) Escherichia coli E24377A 5587819 YP_001463600.1 CDS arnB NC_009801.1 2540785 2541924 D catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2540785..2541924 Escherichia coli E24377A 5588184 YP_001463601.1 CDS arnC NC_009801.1 2541928 2542896 D catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2541928..2542896 Escherichia coli E24377A 5589611 YP_001463602.1 CDS arnA NC_009801.1 2542896 2544878 D Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2542896..2544878 Escherichia coli E24377A 5588571 YP_001463603.1 CDS EcE24377A_2551 NC_009801.1 2544875 2545765 D identified by match to protein family HMM PF01522; polysaccharide deacetylase 2544875..2545765 Escherichia coli E24377A 5589727 YP_001463604.1 CDS arnT NC_009801.1 2545765 2547417 D catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2545765..2547417 Escherichia coli E24377A 5589233 YP_001463605.1 CDS EcE24377A_2553 NC_009801.1 2547414 2547749 D identified by match to protein family HMM PF00893; SMR family multidrug efflux pump 2547414..2547749 Escherichia coli E24377A 5590443 YP_001463606.1 CDS EcE24377A_2555 NC_009801.1 2547749 2548135 D hypothetical protein 2547749..2548135 Escherichia coli E24377A 5589357 YP_001463607.1 CDS pmrD NC_009801.1 2548129 2548395 R identified by similarity to SP:P37590; polymyxin B resistance protein pmrD complement(2548129..2548395) Escherichia coli E24377A 5587872 YP_001463608.1 CDS menE NC_009801.1 2548505 2549860 R identified by match to protein family HMM PF00501; match to protein family HMM TIGR01923; O-succinylbenzoic acid--CoA ligase complement(2548505..2549860) Escherichia coli E24377A 5589835 YP_001463609.1 CDS menC NC_009801.1 2549857 2550819 R catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase complement(2549857..2550819) Escherichia coli E24377A 5588411 YP_001463610.1 CDS menB NC_009801.1 2550819 2551676 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(2550819..2551676) Escherichia coli E24377A 5586938 YP_001463611.1 CDS EcE24377A_2559 NC_009801.1 2551691 2552449 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase complement(2551691..2552449) Escherichia coli E24377A 5586849 YP_001463612.1 CDS menD NC_009801.1 2552446 2554116 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(2552446..2554116) Escherichia coli E24377A 5587984 YP_001463613.1 CDS menF NC_009801.1 2554205 2555500 R identified by similarity to SP:P38051; match to protein family HMM PF00425; match to protein family HMM TIGR00543; menaquinone-specific isochorismate synthase complement(2554205..2555500) Escherichia coli E24377A 5590396 YP_001463614.1 CDS EcE24377A_2563 NC_009801.1 2555579 2555884 R elaB; identified by similarity to GB:CAG75914.1; match to protein family HMM PF05957; hypothetical protein complement(2555579..2555884) Escherichia coli E24377A 5588010 YP_001463615.1 CDS EcE24377A_2564 NC_009801.1 2555939 2556400 R identified by match to protein family HMM PF00583; hypothetical protein complement(2555939..2556400) Escherichia coli E24377A 5587116 YP_001463616.1 CDS rnz NC_009801.1 2556465 2557382 D member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2556465..2557382 Escherichia coli E24377A 5586937 YP_001463617.1 CDS EcE24377A_2566 NC_009801.1 2557573 2558790 D ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system; deubiquitinase 2557573..2558790 Escherichia coli E24377A 5588470 YP_001463618.1 CDS EcE24377A_2568 NC_009801.1 2559920 2560423 D identified by similarity to GB:BAB36582.1; match to protein family HMM PF08974; hypothetical protein 2559920..2560423 Escherichia coli E24377A 5586248 YP_001463619.1 CDS nuoN NC_009801.1 2560490 2561947 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N complement(2560490..2561947) Escherichia coli E24377A 5587353 YP_001463620.1 CDS nuoM NC_009801.1 2561954 2563483 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M complement(2561954..2563483) Escherichia coli E24377A 5586728 YP_001463621.1 CDS nuoL NC_009801.1 2563647 2565488 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L complement(2563647..2565488) Escherichia coli E24377A 5586844 YP_001463622.1 CDS nuoK NC_009801.1 2565485 2565787 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K complement(2565485..2565787) Escherichia coli E24377A 5590713 YP_001463623.1 CDS nuoJ NC_009801.1 2565784 2566338 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J complement(2565784..2566338) Escherichia coli E24377A 5589421 YP_001463624.1 CDS nuoI NC_009801.1 2566350 2566892 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(2566350..2566892) Escherichia coli E24377A 5590693 YP_001463625.1 CDS nuoH NC_009801.1 2566907 2567884 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(2566907..2567884) Escherichia coli E24377A 5589260 YP_001463626.1 CDS nuoG NC_009801.1 2567881 2570607 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(2567881..2570607) Escherichia coli E24377A 5586355 YP_001463627.1 CDS nuoF NC_009801.1 2570660 2571997 R shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F complement(2570660..2571997) Escherichia coli E24377A 5586623 YP_001463628.1 CDS nuoE NC_009801.1 2571994 2572494 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E complement(2571994..2572494) Escherichia coli E24377A 5590838 YP_001463629.1 CDS nuoC NC_009801.1 2572497 2574299 R NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D complement(2572497..2574299) Escherichia coli E24377A 5587429 YP_001463630.1 CDS nuoB NC_009801.1 2574393 2575055 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(2574393..2575055) Escherichia coli E24377A 5588624 YP_001463631.1 CDS nuoA NC_009801.1 2575071 2575514 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A complement(2575071..2575514) Escherichia coli E24377A 5590795 YP_001463632.1 CDS lrhA NC_009801.1 2576145 2577083 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; transcriptional regulator LrhA complement(2576145..2577083) Escherichia coli E24377A 5589406 YP_001463633.1 CDS EcE24377A_2583 NC_009801.1 2578003 2579220 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 2578003..2579220 Escherichia coli E24377A 5587740 YP_001463634.1 CDS yfbR NC_009801.1 2579304 2579903 D identified by similarity to SP:P76491; match to protein family HMM PF01966; hypothetical protein 2579304..2579903 Escherichia coli E24377A 5588997 YP_001463635.1 CDS EcE24377A_2585 NC_009801.1 2579962 2581794 R identified by match to protein family HMM PF02080; match to protein family HMM PF03600; match to protein family HMM PF06808; transporter complement(2579962..2581794) Escherichia coli E24377A 5586985 YP_001463636.1 CDS yfbT NC_009801.1 2581881 2582531 R identified by similarity to SP:P77625; match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; phosphatase complement(2581881..2582531) Escherichia coli E24377A 5587270 YP_001463637.1 CDS EcE24377A_2587 NC_009801.1 2582542 2583036 R identified by match to protein family HMM PF03887; hypothetical protein complement(2582542..2583036) Escherichia coli E24377A 5588185 YP_001463638.1 CDS EcE24377A_2588 NC_009801.1 2583119 2583574 R identified by match to protein family HMM PF04217; hypothetical protein complement(2583119..2583574) Escherichia coli E24377A 5588036 YP_001463639.1 CDS EcE24377A_2589 NC_009801.1 2583643 2583774 R identified by similarity to GB:AAN81291.1; hypothetical protein complement(2583643..2583774) Escherichia coli E24377A 5590240 YP_001463640.1 CDS ackA NC_009801.1 2583912 2585114 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2583912..2585114 Escherichia coli E24377A 5590772 YP_001463641.1 CDS EcE24377A_2591 NC_009801.1 2585189 2587333 D catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2585189..2587333 Escherichia coli E24377A 5590733 YP_001463642.1 CDS EcE24377A_2592 NC_009801.1 2587502 2589043 D identified by match to protein family HMM PF03606; hypothetical protein 2587502..2589043 Escherichia coli E24377A 5588233 YP_001463643.1 CDS EcE24377A_2593 NC_009801.1 2589076 2589618 R identified by match to protein family HMM PF00293; NUDIX family hydrolase complement(2589076..2589618) Escherichia coli E24377A 5588898 YP_001463644.1 CDS EcE24377A_2594 NC_009801.1 2589676 2590227 R identified by similarity to SP:P67095; match to protein family HMM PF00149; match to protein family HMM TIGR00040; phosphodiesterase complement(2589676..2590227) Escherichia coli E24377A 5587809 YP_001463645.1 CDS EcE24377A_2595 NC_009801.1 2590283 2590927 R identified by match to protein family HMM PF02798; glutathione S-transferase domain-containing protein complement(2590283..2590927) Escherichia coli E24377A 5588749 YP_001463646.1 CDS EcE24377A_2596 NC_009801.1 2591063 2591710 D identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase 2591063..2591710 Escherichia coli E24377A 5589314 YP_001463647.1 CDS folX NC_009801.1 2591767 2592129 D catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2591767..2592129 Escherichia coli E24377A 5590760 YP_001463648.1 CDS EcE24377A_2598 NC_009801.1 2592150 2593043 D identified by match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM PF08338; match to protein family HMM TIGR01777; NAD-binding domain-containing protein 2592150..2593043 Escherichia coli E24377A 5587396 YP_001463649.1 CDS EcE24377A_2599 NC_009801.1 2593091 2593981 R identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein complement(2593091..2593981) Escherichia coli E24377A 5589568 YP_001463650.1 CDS hisP NC_009801.1 2594178 2594951 R identified by match to protein family HMM PF00005; histidine/lysine/arginine/ornithine transporter subunit complement(2594178..2594951) Escherichia coli E24377A 5588367 YP_001463651.1 CDS hisM NC_009801.1 2594959 2595675 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; histidine ABC transporter permease HisM complement(2594959..2595675) Escherichia coli E24377A 5587588 YP_001463652.1 CDS hisQ NC_009801.1 2595672 2596358 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; histidine ABC transporter permease HisQ complement(2595672..2596358) Escherichia coli E24377A 5586385 YP_001463653.1 CDS hisJ NC_009801.1 2596448 2597230 R identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096; histidine ABC transporter periplasmic histidine-binding protein complement(2596448..2597230) Escherichia coli E24377A 5588882 YP_001463654.1 CDS argT NC_009801.1 2597451 2598233 R identified by similarity to SP:P09551; match to protein family HMM PF00497; match to protein family HMM TIGR01096; lysine-arginine-ornithine-binding periplasmic protein complement(2597451..2598233) Escherichia coli E24377A 5585981 YP_001463655.1 CDS ubiX NC_009801.1 2598499 2599068 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(2598499..2599068) Escherichia coli E24377A 5588692 YP_001463656.1 CDS purF NC_009801.1 2599163 2600680 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(2599163..2600680) Escherichia coli E24377A 5586729 YP_001463657.1 CDS cvpA NC_009801.1 2600717 2601205 R membrane protein required for colicin V production; colicin V production protein complement(2600717..2601205) Escherichia coli E24377A 5587822 YP_001463658.1 CDS EcE24377A_2608 NC_009801.1 2601464 2602126 R identified by match to protein family HMM PF05036; hypothetical protein complement(2601464..2602126) Escherichia coli E24377A 5587533 YP_001463659.1 CDS folC NC_009801.1 2602116 2603384 R identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase complement(2602116..2603384) Escherichia coli E24377A 5589962 YP_001463660.1 CDS accD NC_009801.1 2603454 2604368 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(2603454..2604368) Escherichia coli E24377A 5588950 YP_001463661.1 CDS EcE24377A_2611 NC_009801.1 2604524 2605183 R identified by match to protein family HMM PF09335; hypothetical protein complement(2604524..2605183) Escherichia coli E24377A 5589138 YP_001463662.1 CDS truA NC_009801.1 2605266 2606078 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(2605266..2606078) Escherichia coli E24377A 5588877 YP_001463663.1 CDS EcE24377A_2613 NC_009801.1 2606078 2607091 R identified by similarity to SP:P08390; match to protein family HMM PF01118; match to protein family HMM PF02774; semialdehyde dehydrogenase complement(2606078..2607091) Escherichia coli E24377A 5590066 YP_001463664.1 CDS EcE24377A_2615 NC_009801.1 2607072 2607185 D identified by glimmer; hypothetical protein 2607072..2607185 Escherichia coli E24377A 5589738 YP_001463665.1 CDS pdxB NC_009801.1 2607157 2608293 R identified by similarity to SP:P05459; match to protein family HMM PF00389; match to protein family HMM PF02826; erythronate-4-phosphate dehydrogenase complement(2607157..2608293) Escherichia coli E24377A 5590697 YP_001463666.1 CDS flk NC_009801.1 2608393 2609397 D in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2608393..2609397 Escherichia coli E24377A 5588628 YP_001463667.1 CDS EcE24377A_2616 NC_009801.1 2609394 2610572 R identified by match to protein family HMM PF07690; hypothetical protein complement(2609394..2610572) Escherichia coli E24377A 5588945 YP_001463668.1 CDS fabB NC_009801.1 2610804 2612024 R FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(2610804..2612024) Escherichia coli E24377A 5589877 YP_001463669.1 CDS mnmC NC_009801.1 2612183 2614189 D catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2612183..2614189 Escherichia coli E24377A 5587831 YP_001463670.1 CDS EcE24377A_2620 NC_009801.1 2614245 2614523 R identified by similarity to GB:ABB66925.1; match to protein family HMM PF08891; hypothetical protein complement(2614245..2614523) Escherichia coli E24377A 5587905 YP_001463671.1 CDS EcE24377A_2621 NC_009801.1 2614557 2615105 R identified by match to protein family HMM PF04315; hypothetical protein complement(2614557..2615105) Escherichia coli E24377A 5587343 YP_001463672.1 CDS EcE24377A_2622 NC_009801.1 2615105 2615914 R identified by match to protein family HMM PF01925; hypothetical protein complement(2615105..2615914) Escherichia coli E24377A 5590646 YP_001463673.1 CDS mepA NC_009801.1 2615914 2616738 R D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase complement(2615914..2616738) Escherichia coli E24377A 5587163 YP_001463674.1 CDS aroC NC_009801.1 2616742 2617827 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(2616742..2617827) Escherichia coli E24377A 5586436 YP_001463675.1 CDS prmB NC_009801.1 2617986 2618918 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(2617986..2618918) Escherichia coli E24377A 5588605 YP_001463676.1 CDS EcE24377A_2626 NC_009801.1 2619084 2619635 D identified by match to protein family HMM PF01713; hypothetical protein 2619084..2619635 Escherichia coli E24377A 5588603 YP_001463677.1 CDS EcE24377A_2627 NC_009801.1 2619708 2620577 R identified by similarity to GB:ABB66932.1; hypothetical protein complement(2619708..2620577) Escherichia coli E24377A 5590814 YP_001463678.1 CDS EcE24377A_2628 NC_009801.1 2620564 2621103 R identified by match to protein family HMM PF00419; fimbrial protein complement(2620564..2621103) Escherichia coli E24377A 5586308 YP_001463679.1 CDS EcE24377A_2629 NC_009801.1 2621100 2621588 R hypothetical protein complement(2621100..2621588) Escherichia coli E24377A 5589006 YP_001463680.1 CDS EcE24377A_2630 NC_009801.1 2621585 2622088 R identified by similarity to GB:AAV76235.1; fimbrial protein complement(2621585..2622088) Escherichia coli E24377A 5588441 YP_001463681.1 CDS EcE24377A_2631 NC_009801.1 2622104 2622829 R identified by match to protein family HMM PF00345; periplasmic pilus chaperone family protein complement(2622104..2622829) Escherichia coli E24377A 5590575 YP_001463682.1 CDS EcE24377A_2633 NC_009801.1 2622702 2622890 D identified by glimmer; hypothetical protein 2622702..2622890 Escherichia coli E24377A 5588804 YP_001463683.1 CDS EcE24377A_2632 NC_009801.1 2622876 2625521 R identified by match to protein family HMM PF00577; fimbrial usher family protein complement(2622876..2625521) Escherichia coli E24377A 5590056 YP_001463684.1 CDS EcE24377A_2635 NC_009801.1 2625510 2626046 D identified by glimmer; hypothetical protein 2625510..2626046 Escherichia coli E24377A 5586447 YP_001463685.1 CDS EcE24377A_2634 NC_009801.1 2625603 2626166 R identified by similarity to GB:AAC64152.1; match to protein family HMM PF00419; fimbrial protein complement(2625603..2626166) Escherichia coli E24377A 5586835 YP_001463686.1 CDS sixA NC_009801.1 2626850 2627335 R identified by match to protein family HMM PF00300; match to protein family HMM TIGR00249; phosphohistidine phosphatase complement(2626850..2627335) Escherichia coli E24377A 5590075 YP_001463687.1 CDS fadJ NC_009801.1 2627538 2629682 R multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha complement(2627538..2629682) Escherichia coli E24377A 5588861 YP_001463688.1 CDS fadI NC_009801.1 2629682 2630992 R FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase complement(2629682..2630992) Escherichia coli E24377A 5590384 YP_001463689.1 CDS EcE24377A_2639 NC_009801.1 2631172 2631456 R identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743; hypothetical protein complement(2631172..2631456) Escherichia coli E24377A 5588063 YP_001463690.1 CDS EcE24377A_2640 NC_009801.1 2631828 2633168 D identified by match to protein family HMM PF03349; long-chain fatty acid outer membrane transporter 2631828..2633168 Escherichia coli E24377A 5586390 YP_001463691.1 CDS EcE24377A_2641 NC_009801.1 2633535 2634593 D identified by similarity to GB:AAP17747.1; hypothetical protein 2633535..2634593 Escherichia coli E24377A 5586567 YP_001463692.1 CDS EcE24377A_2642 NC_009801.1 2634775 2635530 R identified by match to protein family HMM PF04333; VacJ family lipoprotein complement(2634775..2635530) Escherichia coli E24377A 5590471 YP_001463693.1 CDS EcE24377A_2643 NC_009801.1 2635556 2635726 R identified by similarity to GB:AAN81341.1; hypothetical protein complement(2635556..2635726) Escherichia coli E24377A 5589134 YP_001463694.1 CDS EcE24377A_2644 NC_009801.1 2635824 2636756 D hypothetical protein 2635824..2636756 Escherichia coli E24377A 5586683 YP_001463695.1 CDS lacY NC_009801.1 2637347 2638594 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(2637347..2638594) Escherichia coli E24377A 5589143 YP_001463696.1 CDS cscK NC_009801.1 2638666 2639580 R phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase complement(2638666..2639580) Escherichia coli E24377A 5588045 YP_001463697.1 CDS EcE24377A_2648 NC_009801.1 2639702 2639794 D identified by glimmer; hypothetical protein 2639702..2639794 Escherichia coli E24377A 5588290 YP_001463698.1 CDS EcE24377A_2649 NC_009801.1 2639787 2641229 D identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322; sucrose-6-phosphate hydrolase 2639787..2641229 Escherichia coli E24377A 5586160 YP_001463699.1 CDS EcE24377A_2650 NC_009801.1 2641237 2642232 R identified by match to protein family HMM PF00356; match to protein family HMM PF00532; LacI family sucrose operon repressor complement(2641237..2642232) Escherichia coli E24377A 5586147 YP_001463700.1 CDS EcE24377A_2651 NC_009801.1 2642475 2642693 D identified by glimmer; hypothetical protein 2642475..2642693 Escherichia coli E24377A 5586441 YP_001463701.1 CDS dsdA NC_009801.1 2642711 2644039 D catalyzes the formation of pyruvate from serine; D-serine dehydratase 2642711..2644039 Escherichia coli E24377A 5586459 YP_001463702.1 CDS emrY NC_009801.1 2644147 2645685 R identified by similarity to SP:P52600; match to protein family HMM PF07690; match to protein family HMM TIGR00711; DHA2 family drug:H+ antiporter-1 complement(2644147..2645685) Escherichia coli E24377A 5590262 YP_001463703.1 CDS emrK NC_009801.1 2645685 2646848 R identified by similarity to SP:P52599; match to protein family HMM PF00529; match to protein family HMM TIGR00998; drug resistance MFS transporter membrane fusion protein (MFP) subunit EmrK complement(2645685..2646848) Escherichia coli E24377A 5589823 YP_001463704.1 CDS evgA NC_009801.1 2647264 2647878 D response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 2647264..2647878 Escherichia coli E24377A 5588369 YP_001463705.1 CDS evgS NC_009801.1 2647883 2651476 D identified by match to protein family HMM PF00072; match to protein family HMM PF00497; match to protein family HMM PF00512; match to protein family HMM PF01627; match to protein family HMM PF02518; hybrid sensory histidine kinase in two-component regulatory system with EvgA 2647883..2651476 Escherichia coli E24377A 5587935 YP_001463706.1 CDS EcE24377A_2656 NC_009801.1 2651252 2651350 R identified by glimmer; hypothetical protein complement(2651252..2651350) Escherichia coli E24377A 5590293 YP_001463707.1 CDS EcE24377A_2658 NC_009801.1 2651532 2652677 R identified by match to protein family HMM PF02515; hypothetical protein complement(2651532..2652677) Escherichia coli E24377A 5586072 YP_001463708.1 CDS EcE24377A_2660 NC_009801.1 2652671 2652775 D identified by glimmer; hypothetical protein 2652671..2652775 Escherichia coli E24377A 5589613 YP_001463709.1 CDS EcE24377A_2659 NC_009801.1 2652751 2653695 R member of the AEC family of auxin efflux transporters; unknown function; transporter YfdV complement(2652751..2653695) Escherichia coli E24377A 5589686 YP_001463710.1 CDS EcE24377A_2661 NC_009801.1 2653765 2655459 R catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase complement(2653765..2655459) Escherichia coli E24377A 5588127 YP_001463711.1 CDS frc NC_009801.1 2655513 2656763 R catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase complement(2655513..2656763) Escherichia coli E24377A 5586087 YP_001463712.1 CDS EcE24377A_2663 NC_009801.1 2657276 2657908 R identified by similarity to GB:AAZ89107.1; hypothetical protein complement(2657276..2657908) Escherichia coli E24377A 5589157 YP_001463713.1 CDS EcE24377A_2664 NC_009801.1 2658464 2658601 R identified by glimmer; hypothetical protein complement(2658464..2658601) Escherichia coli E24377A 5589104 YP_001463714.1 CDS EcE24377A_2665 NC_009801.1 2658556 2658798 R identified by similarity to GB:AAZ89109.1; hypothetical protein complement(2658556..2658798) Escherichia coli E24377A 5587502 YP_001463715.1 CDS EcE24377A_2666 NC_009801.1 2659151 2660071 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2659151..2660071 Escherichia coli E24377A 5586700 YP_001463716.1 CDS EcE24377A_2667 NC_009801.1 2660381 2660497 D identified by glimmer; hypothetical protein 2660381..2660497 Escherichia coli E24377A 5590553 YP_001463717.1 CDS EcE24377A_2668 NC_009801.1 2660562 2661800 R identified by match to protein family HMM PF00155; aminotransferase complement(2660562..2661800) Escherichia coli E24377A 5586641 YP_001463718.1 CDS EcE24377A_2669 NC_009801.1 2661719 2661853 R identified by glimmer; hypothetical protein complement(2661719..2661853) Escherichia coli E24377A 5586754 YP_001463719.1 CDS EcE24377A_2670 NC_009801.1 2662195 2663874 D identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694; sensor histidine kinase 2662195..2663874 Escherichia coli E24377A 5586671 YP_001463720.1 CDS EcE24377A_2671 NC_009801.1 2663889 2664623 D identified by match to protein family HMM PF00072; match to protein family HMM PF04397; response regulator 2663889..2664623 Escherichia coli E24377A 5589798 YP_001463721.1 CDS EcE24377A_2672 NC_009801.1 2664636 2665493 D identified by match to protein family HMM PF00165; AraC family transcriptional regulator 2664636..2665493 Escherichia coli E24377A 5588930 YP_001463722.1 CDS fryA NC_009801.1 2665496 2667991 R identified by match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR00848; match to protein family HMM TIGR01417; multiphosphoryl transfer protein 1 complement(2665496..2667991) Escherichia coli E24377A 5589181 YP_001463723.1 CDS EcE24377A_2674 NC_009801.1 2668016 2669053 R metalloprotein; exoaminopeptidase complement(2668016..2669053) Escherichia coli E24377A 5590350 YP_001463724.1 CDS ypdF NC_009801.1 2669053 2670138 R Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase complement(2669053..2670138) Escherichia coli E24377A 5587145 YP_001463725.1 CDS fryC NC_009801.1 2670153 2671400 R identified by similarity to SP:Q8XBP8; match to protein family HMM PF02378; match to protein family HMM TIGR01427; PTS system fructose-like transporter subunit IIC complement(2670153..2671400) Escherichia coli E24377A 5588594 YP_001463726.1 CDS EcE24377A_2677 NC_009801.1 2671422 2671748 R identified by match to protein family HMM PF02379; match to protein family HMM TIGR00829; PTS system fructose specific transporter subunit IIB subunit complement(2671422..2671748) Escherichia coli E24377A 5589003 YP_001463727.1 CDS glk NC_009801.1 2671967 2672932 R catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase complement(2671967..2672932) Escherichia coli E24377A 5589600 YP_001463728.1 CDS EcE24377A_2679 NC_009801.1 2673136 2674392 D hypothetical protein 2673136..2674392 Escherichia coli E24377A 5590007 YP_001463729.1 CDS EcE24377A_2680 NC_009801.1 2674409 2674507 R identified by glimmer; hypothetical protein complement(2674409..2674507) Escherichia coli E24377A 5588635 YP_001463730.1 CDS EcE24377A_2681 NC_009801.1 2674507 2674833 D identified by similarity to SP:P64544; hypothetical protein 2674507..2674833 Escherichia coli E24377A 5588166 YP_001463731.1 CDS mntH NC_009801.1 2674974 2676212 R identified by match to protein family HMM PF01566; match to protein family HMM TIGR01197; manganese transport protein MntH complement(2674974..2676212) Escherichia coli E24377A 5590069 YP_001463732.1 CDS nupC NC_009801.1 2676548 2677750 D identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804; nucleoside transporter NupC 2676548..2677750 Escherichia coli E24377A 5590548 YP_001463733.1 CDS EcE24377A_2684 NC_009801.1 2677800 2679989 R identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF05231; diguanylate cyclase complement(2677800..2679989) Escherichia coli E24377A 5590270 YP_001463734.1 CDS EcE24377A_2687 NC_009801.1 2680623 2680967 D hypothetical protein 2680623..2680967 Escherichia coli E24377A 5586561 YP_001463735.1 CDS EcE24377A_2688 NC_009801.1 2680969 2681361 D identified by match to protein family HMM PF07037; hypothetical protein 2680969..2681361 Escherichia coli E24377A 5588420 YP_001463736.1 CDS gltX NC_009801.1 2681413 2682828 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(2681413..2682828) Escherichia coli E24377A 5585918 YP_001463737.1 CDS EcE24377A_2695 NC_009801.1 2683605 2683946 D identified by similarity to GB:AAP17783.1; hypothetical protein 2683605..2683946 Escherichia coli E24377A 5587465 YP_001463738.1 CDS EcE24377A_2694 NC_009801.1 2683937 2684863 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(2683937..2684863) Escherichia coli E24377A 5587640 YP_001463739.1 CDS EcE24377A_2697 NC_009801.1 2684953 2685951 D identified by match to protein family HMM PF01758; bile acid/Na+ symporter family protein 2684953..2685951 Escherichia coli E24377A 5586161 YP_001463740.1 CDS EcE24377A_2696 NC_009801.1 2685948 2686166 R identified by similarity to SP:P0AD40; hypothetical protein complement(2685948..2686166) Escherichia coli E24377A 5587925 YP_001463741.1 CDS ligA NC_009801.1 2686168 2688183 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(2686168..2688183) Escherichia coli E24377A 5588540 YP_001463742.1 CDS zipA NC_009801.1 2688254 2689240 R interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA complement(2688254..2689240) Escherichia coli E24377A 5588706 YP_001463743.1 CDS cysZ NC_009801.1 2689470 2690231 D role in sulfur assimilation; sulfate transport protein CysZ 2689470..2690231 Escherichia coli E24377A 5586863 YP_001463744.1 CDS cysK NC_009801.1 2690416 2691387 D CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2690416..2691387 Escherichia coli E24377A 5588839 YP_001463745.1 CDS ptsH NC_009801.1 2691771 2692028 D identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003; PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr 2691771..2692028 Escherichia coli E24377A 5587823 YP_001463746.1 CDS ptsI NC_009801.1 2692073 2693800 D Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 2692073..2693800 Escherichia coli E24377A 5589769 YP_001463747.1 CDS crr NC_009801.1 2693841 2694350 D functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 2693841..2694350 Escherichia coli E24377A 5590456 YP_001463748.1 CDS pdxK NC_009801.1 2694392 2695243 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase complement(2694392..2695243) Escherichia coli E24377A 5588451 YP_001463749.1 CDS EcE24377A_2706 NC_009801.1 2695348 2695716 D identified by similarity to GB:ABB66999.1; hypothetical protein 2695348..2695716 Escherichia coli E24377A 5586544 YP_001463750.1 CDS cysM NC_009801.1 2695719 2696630 R catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B complement(2695719..2696630) Escherichia coli E24377A 5587303 YP_001463751.1 CDS cysA NC_009801.1 2696764 2697861 R identified by match to protein family HMM PF00005; match to protein family HMM TIGR00968; sulfate/thiosulfate transporter subunit complement(2696764..2697861) Escherichia coli E24377A 5590564 YP_001463752.1 CDS cysW NC_009801.1 2697851 2698726 R Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit complement(2697851..2698726) Escherichia coli E24377A 5587686 YP_001463753.1 CDS cysT NC_009801.1 2698726 2699559 R identified by similarity to SP:P16701; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139; sulfate/thiosulfate transporter subunit complement(2698726..2699559) Escherichia coli E24377A 5586639 YP_001463754.1 CDS cysP NC_009801.1 2699559 2700575 R identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971; thiosulfate transporter subunit complement(2699559..2700575) Escherichia coli E24377A 5589644 YP_001463755.1 CDS ucpA NC_009801.1 2700733 2701524 R identified by similarity to SP:P37440; match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659; short chain dehydrogenase complement(2700733..2701524) Escherichia coli E24377A 5589587 YP_001463756.1 CDS EcE24377A_2713 NC_009801.1 2701653 2702510 R identified by match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR family transcriptional regulator complement(2701653..2702510) Escherichia coli E24377A 5588154 YP_001463757.1 CDS murQ NC_009801.1 2702674 2703570 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 2702674..2703570 Escherichia coli E24377A 5589393 YP_001463758.1 CDS murP NC_009801.1 2703574 2704998 D belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunit IIBC 2703574..2704998 Escherichia coli E24377A 5589551 YP_001463759.1 CDS EcE24377A_2716 NC_009801.1 2705003 2706307 D identified by match to protein family HMM PF00144; hypothetical protein 2705003..2706307 Escherichia coli E24377A 5588899 YP_001463760.1 CDS EcE24377A_2717 NC_009801.1 2706365 2707264 R identified by match to protein family HMM PF04261; match to protein family HMM TIGR01413; dyp-type peroxidase complement(2706365..2707264) Escherichia coli E24377A 5590103 YP_001463761.1 CDS EcE24377A_2718 NC_009801.1 2707360 2707935 R identified by match to protein family HMM PF06572; hypothetical protein complement(2707360..2707935) Escherichia coli E24377A 5589105 YP_001463762.1 CDS EcE24377A_2719 NC_009801.1 2707996 2708445 R inner membrane protein YfeZ complement(2707996..2708445) Escherichia coli E24377A 5590373 YP_001463763.1 CDS EcE24377A_2720 NC_009801.1 2708432 2708857 R identified by match to protein family HMM PF00583; acetyltransferase complement(2708432..2708857) Escherichia coli E24377A 5587024 YP_001463764.1 CDS amiA NC_009801.1 2709071 2709940 D identified by similarity to SP:P36548; match to protein family HMM PF01520; match to protein family HMM TIGR01409; N-acetylmuramoyl-L-alanine amidase 2709071..2709940 Escherichia coli E24377A 5588844 YP_001463765.1 CDS hemF NC_009801.1 2709944 2710843 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2709944..2710843 Escherichia coli E24377A 5587529 YP_001463766.1 CDS EcE24377A_2723 NC_009801.1 2710849 2711901 R activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR complement(2710849..2711901) Escherichia coli E24377A 5588788 YP_001463767.1 CDS EcE24377A_2724 NC_009801.1 2711947 2712447 R identified by similarity to SP:Q9ZFU8; match to protein family HMM PF00936; ethanolamine utilization protein EutK complement(2711947..2712447) Escherichia coli E24377A 5587223 YP_001463768.1 CDS EcE24377A_2725 NC_009801.1 2712460 2713119 R identified by similarity to SP:P0A1C9; match to protein family HMM PF00936; ethanolamine utilization protein EutL complement(2712460..2713119) Escherichia coli E24377A 5587559 YP_001463769.1 CDS eutC NC_009801.1 2713129 2714016 R catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit complement(2713129..2714016) Escherichia coli E24377A 5590410 YP_001463770.1 CDS eutB NC_009801.1 2714037 2715398 R identified by similarity to SP:P19264; match to protein family HMM PF06751; ethanolamine ammonia-lyase, large subunit complement(2714037..2715398) Escherichia coli E24377A 5586520 YP_001463771.1 CDS eutA NC_009801.1 2715410 2716813 R ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase complement(2715410..2716813) Escherichia coli E24377A 5588072 YP_001463772.1 CDS eutH NC_009801.1 2716810 2718036 R identified by similarity to SP:P41796; match to protein family HMM PF04346; ethanolamine utilization protein EutH complement(2716810..2718036) Escherichia coli E24377A 5590179 YP_001463773.1 CDS eutG NC_009801.1 2718153 2719340 R identified by similarity to SP:P41795; match to protein family HMM PF00465; ethanolamine utilization protein EutG complement(2718153..2719340) Escherichia coli E24377A 5585958 YP_001463774.1 CDS eutJ NC_009801.1 2719330 2720166 R identified by similarity to SP:P0A206; match to protein family HMM TIGR02529; ethanolamine utilization protein EutJ complement(2719330..2720166) Escherichia coli E24377A 5588241 YP_001463775.1 CDS eutE NC_009801.1 2720177 2721580 R identified by similarity to SP:P41793; match to protein family HMM PF00171; ethanolamine utilization protein EutE complement(2720177..2721580) Escherichia coli E24377A 5590791 YP_001463776.1 CDS eutN NC_009801.1 2721592 2721879 R identified by similarity to SP:P41792; match to protein family HMM PF03319; ethanolamine utilization protein complement(2721592..2721879) Escherichia coli E24377A 5590400 YP_001463777.1 CDS eutM NC_009801.1 2721986 2722279 R identified by match to protein family HMM PF00936; ethanolamine utilization protein EutM complement(2721986..2722279) Escherichia coli E24377A 5586316 YP_001463778.1 CDS eutD NC_009801.1 2722318 2723334 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(2722318..2723334) Escherichia coli E24377A 5590810 YP_001463779.1 CDS eutT NC_009801.1 2723331 2724134 R identified by similarity to SP:Q9ZFV4; match to protein family HMM PF01923; ethanolamine utilization cobalamin adenosyltransferase complement(2723331..2724134) Escherichia coli E24377A 5588949 YP_001463780.1 CDS EcE24377A_2737 NC_009801.1 2724131 2724832 R identified by match to protein family HMM PF05899; match to protein family HMM PF06249; ethanolamine utilization protein EutQ complement(2724131..2724832) Escherichia coli E24377A 5586492 YP_001463781.1 CDS eutP NC_009801.1 2724807 2725286 R identified by similarity to SP:P0A208; match to protein family HMM TIGR02528; ethanolamine utilization protein, EutP complement(2724807..2725286) Escherichia coli E24377A 5586625 YP_001463782.1 CDS EcE24377A_2739 NC_009801.1 2725299 2725706 R identified by similarity to SP:Q9ZFV7; match to protein family HMM PF00936; ethanolamine utilization protein EutS complement(2725299..2725706) Escherichia coli E24377A 5588442 YP_001463783.1 CDS EcE24377A_2740 NC_009801.1 2725563 2725670 D identified by glimmer; hypothetical protein 2725563..2725670 Escherichia coli E24377A 5587407 YP_001463784.1 CDS maeB NC_009801.1 2725927 2728206 R NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(2725927..2728206) Escherichia coli E24377A 5586471 YP_001463785.1 CDS tal1 NC_009801.1 2728495 2729445 D identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874; transaldolase A 2728495..2729445 Escherichia coli E24377A 5589024 YP_001463786.1 CDS tktB NC_009801.1 2729465 2731468 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2729465..2731468 Escherichia coli E24377A 5586382 YP_001463787.1 CDS EcE24377A_2745 NC_009801.1 2731461 2731574 D identified by glimmer; hypothetical protein 2731461..2731574 Escherichia coli E24377A 5585905 YP_001463788.1 CDS EcE24377A_2744 NC_009801.1 2731564 2732607 R identified by similarity to GB:ABB67033.1; match to protein family HMM PF06674; hypothetical protein complement(2731564..2732607) Escherichia coli E24377A 5589933 YP_001463789.1 CDS EcE24377A_2746 NC_009801.1 2732733 2733308 R identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052; NUDIX family hydrolase complement(2732733..2733308) Escherichia coli E24377A 5587625 YP_001463790.1 CDS aegA NC_009801.1 2733376 2735355 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(2733376..2735355) Escherichia coli E24377A 5588586 YP_001463791.1 CDS narQ NC_009801.1 2735561 2737261 D identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730; nitrate/nitrite sensor protein NarQ 2735561..2737261 Escherichia coli E24377A 5588686 YP_001463792.1 CDS acrD NC_009801.1 2737425 2740538 D identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; aminoglycoside/multidrug efflux system 2737425..2740538 Escherichia coli E24377A 5587667 YP_001463793.1 CDS EcE24377A_2750 NC_009801.1 2741077 2741433 D identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; hypothetical protein 2741077..2741433 Escherichia coli E24377A 5590106 YP_001463794.1 CDS dapE NC_009801.1 2741437 2742564 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2741437..2742564 Escherichia coli E24377A 5586953 YP_001463795.1 CDS EcE24377A_2752 NC_009801.1 2742592 2742792 D identified by similarity to GB:AAN81450.1; hypothetical protein 2742592..2742792 Escherichia coli E24377A 5590702 YP_001463796.1 CDS EcE24377A_2753 NC_009801.1 2742873 2743571 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase complement(2742873..2743571) Escherichia coli E24377A 5589720 YP_001463797.1 CDS EcE24377A_2754 NC_009801.1 2743645 2745660 R identified by similarity to GB:ABB62712.1; match to protein family HMM PF05127; hypothetical protein complement(2743645..2745660) Escherichia coli E24377A 5590673 YP_001463798.1 CDS EcE24377A_2755 NC_009801.1 2745675 2746538 R identified by match to protein family HMM PF04228; hypothetical protein complement(2745675..2746538) Escherichia coli E24377A 5588236 YP_001463799.1 CDS EcE24377A_2756 NC_009801.1 2747083 2747310 R identified by similarity to GB:AAL23544.1; hypothetical protein complement(2747083..2747310) Escherichia coli E24377A 5586096 YP_001463800.1 CDS purC NC_009801.1 2747464 2748177 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(2747464..2748177) Escherichia coli E24377A 5589830 YP_001463801.1 CDS EcE24377A_2758 NC_009801.1 2748183 2748290 R identified by glimmer; hypothetical protein complement(2748183..2748290) Escherichia coli E24377A 5587200 YP_001463802.1 CDS EcE24377A_2759 NC_009801.1 2748390 2749424 R identified by match to protein family HMM PF06804; lipoprotein complement(2748390..2749424) Escherichia coli E24377A 5586197 YP_001463803.1 CDS dapA NC_009801.1 2749441 2750319 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(2749441..2750319) Escherichia coli E24377A 5589914 YP_001463804.1 CDS gcvR NC_009801.1 2750399 2751037 D negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2750399..2751037 Escherichia coli E24377A 5586809 YP_001463805.1 CDS bcp NC_009801.1 2751037 2751507 D bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2751037..2751507 Escherichia coli E24377A 5588245 YP_001463806.1 CDS EcE24377A_2763 NC_009801.1 2751760 2752377 D identified by match to protein family HMM PF00037; (Fe-S)-binding protein 2751760..2752377 Escherichia coli E24377A 5590345 YP_001463807.1 CDS hyfC NC_009801.1 2754405 2755349 D identified by similarity to SP:P16430; similarity to SP:P77858; match to protein family HMM PF00146; hydrogenase-4 subunit C 2754405..2755349 Escherichia coli E24377A 5588350 YP_001463808.1 CDS hyfE NC_009801.1 2756607 2757257 D interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit 2756607..2757257 Escherichia coli E24377A 5587747 YP_001463809.1 CDS EcE24377A_2769 NC_009801.1 2758838 2760553 D identified by similarity to SP:P77329; match to protein family HMM PF00329; match to protein family HMM PF00346; hydrogenase-4, G subunit 2758838..2760553 Escherichia coli E24377A 5589080 YP_001463810.1 CDS EcE24377A_2770 NC_009801.1 2760563 2761108 D probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H 2760563..2761108 Escherichia coli E24377A 5589717 YP_001463811.1 CDS EcE24377A_2771 NC_009801.1 2761105 2761863 D identified by similarity to SP:P77668; match to protein family HMM PF01058; hydrogenase-4, I subunit 2761105..2761863 Escherichia coli E24377A 5589495 YP_001463812.1 CDS EcE24377A_2772 NC_009801.1 2761856 2762269 D identified by match to protein family HMM PF07450; formate hydrogenlyase maturation protein HycH 2761856..2762269 Escherichia coli E24377A 5586301 YP_001463813.1 CDS EcE24377A_2773 NC_009801.1 2762299 2764311 D identified by similarity to SP:P19323; match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; formate hydrogenlyase transcriptional activator 2762299..2764311 Escherichia coli E24377A 5586660 YP_001463814.1 CDS focB NC_009801.1 2764333 2765181 D inner membrane protein presumed to act as a formate transporter; member of the hyf operon; formate transporter 2764333..2765181 Escherichia coli E24377A 5589397 YP_001463815.1 CDS EcE24377A_2775 NC_009801.1 2765219 2766280 R identified by match to protein family HMM PF01594; PerM family permease complement(2765219..2766280) Escherichia coli E24377A 5587052 YP_001463816.1 CDS EcE24377A_2776 NC_009801.1 2766493 2767956 D identified by match to protein family HMM PF01435; M48 family peptidase 2766493..2767956 Escherichia coli E24377A 5590536 YP_001463817.1 CDS EcE24377A_2778 NC_009801.1 2768350 2768460 R identified by glimmer; hypothetical protein complement(2768350..2768460) Escherichia coli E24377A 5587274 YP_001463818.1 CDS hda NC_009801.1 2768473 2769219 R controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor complement(2768473..2769219) Escherichia coli E24377A 5590507 YP_001463819.1 CDS uraA NC_009801.1 2769269 2770558 R identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; uracil transporter complement(2769269..2770558) Escherichia coli E24377A 5586000 YP_001463820.1 CDS upp NC_009801.1 2770644 2771270 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(2770644..2771270) Escherichia coli E24377A 5586236 YP_001463821.1 CDS purM NC_009801.1 2771595 2772632 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2771595..2772632 Escherichia coli E24377A 5589552 YP_001463822.1 CDS purN NC_009801.1 2772632 2773270 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2772632..2773270 Escherichia coli E24377A 5589096 YP_001463823.1 CDS ppk NC_009801.1 2773441 2775507 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2773441..2775507 Escherichia coli E24377A 5586637 YP_001463824.1 CDS ppx NC_009801.1 2775512 2777053 D identified by match to protein family HMM PF02541; exopolyphosphatase 2775512..2777053 Escherichia coli E24377A 5590187 YP_001463825.1 CDS EcE24377A_2786 NC_009801.1 2777092 2779335 R identified by match to protein family HMM PF00563; match to protein family HMM PF05231; cyclic diguanylate phosphodiesterase domain-containing protein complement(2777092..2779335) Escherichia coli E24377A 5587562 YP_001463826.1 CDS EcE24377A_2787 NC_009801.1 2779517 2779669 R identified by similarity to GB:AAG57614.1; hypothetical protein complement(2779517..2779669) Escherichia coli E24377A 5588137 YP_001463827.1 CDS EcE24377A_2788 NC_009801.1 2779687 2779878 D identified by similarity to GB:AAL21400.1; hypothetical protein 2779687..2779878 Escherichia coli E24377A 5587496 YP_001463828.1 CDS EcE24377A_2789 NC_009801.1 2780192 2780707 D identified by match to protein family HMM PF05433; surface antigen family protein 2780192..2780707 Escherichia coli E24377A 5589340 YP_001463829.1 CDS EcE24377A_2790 NC_009801.1 2780723 2781262 D identified by similarity to SP:P76573; hypothetical protein 2780723..2781262 Escherichia coli E24377A 5586932 YP_001463830.1 CDS guaA NC_009801.1 2781357 2782934 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(2781357..2782934) Escherichia coli E24377A 5588110 YP_001463831.1 CDS guaB NC_009801.1 2783003 2784469 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(2783003..2784469) Escherichia coli E24377A 5588906 YP_001463832.1 CDS EcE24377A_2793 NC_009801.1 2785998 2786213 R identified by similarity to GB:AAZ89220.1; match to protein family HMM PF07191; hypothetical protein complement(2785998..2786213) Escherichia coli E24377A 5589320 YP_001463833.1 CDS engA NC_009801.1 2786282 2787754 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(2786282..2787754) Escherichia coli E24377A 5590580 YP_001463834.1 CDS EcE24377A_2796 NC_009801.1 2787872 2789050 R with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL complement(2787872..2789050) Escherichia coli E24377A 5589354 YP_001463835.1 CDS EcE24377A_2797 NC_009801.1 2789061 2789681 R identified by similarity to GB:AAP83327.1; hypothetical protein complement(2789061..2789681) Escherichia coli E24377A 5587900 YP_001463836.1 CDS hisS NC_009801.1 2789699 2790973 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2789699..2790973) Escherichia coli E24377A 5590346 YP_001463837.1 CDS ispG NC_009801.1 2791084 2792202 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(2791084..2792202) Escherichia coli E24377A 5587678 YP_001463838.1 CDS EcE24377A_2800 NC_009801.1 2792229 2793242 R identified by match to protein family HMM PF01381; cytoskeletal protein RodZ complement(2792229..2793242) Escherichia coli E24377A 5589550 YP_001463839.1 CDS EcE24377A_2801 NC_009801.1 2793527 2794681 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(2793527..2794681) Escherichia coli E24377A 5590162 YP_001463840.1 CDS ndk NC_009801.1 2794831 2795262 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(2794831..2795262) Escherichia coli E24377A 5588918 YP_001463841.1 CDS pbpC NC_009801.1 2795411 2797723 R penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C complement(2795411..2797723) Escherichia coli E24377A 5590236 YP_001463842.1 CDS EcE24377A_2804 NC_009801.1 2797724 2802685 R identified by match to protein family HMM PF01835; match to protein family HMM PF07703; alpha-2-macroglobulin complement(2797724..2802685) Escherichia coli E24377A 5589744 YP_001463843.1 CDS sseA NC_009801.1 2802892 2803737 D catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2802892..2803737 Escherichia coli E24377A 5590039 YP_001463844.1 CDS sseB NC_009801.1 2804230 2805006 R enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB complement(2804230..2805006) Escherichia coli E24377A 5587334 YP_001463845.1 CDS pepB NC_009801.1 2805148 2806431 R catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase complement(2805148..2806431) Escherichia coli E24377A 5587749 YP_001463846.1 CDS iscX NC_009801.1 2806609 2806809 R identified by similarity to SP:P0C0L9; match to protein family HMM PF04384; match to protein family HMM TIGR03412; hypothetical protein complement(2806609..2806809) Escherichia coli E24377A 5588582 YP_001463847.1 CDS fdx NC_009801.1 2806821 2807156 R identified by match to protein family HMM PF00111; match to protein family HMM TIGR02007; (2Fe-2S) ferredoxin complement(2806821..2807156) Escherichia coli E24377A 5586514 YP_001463848.1 CDS hscA NC_009801.1 2807158 2809008 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(2807158..2809008) Escherichia coli E24377A 5588883 YP_001463849.1 CDS hscB NC_009801.1 2809025 2809540 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(2809025..2809540) Escherichia coli E24377A 5587189 YP_001463850.1 CDS EcE24377A_2812 NC_009801.1 2809548 2809664 R identified by glimmer; hypothetical protein complement(2809548..2809664) Escherichia coli E24377A 5587979 YP_001463851.1 CDS iscA NC_009801.1 2809636 2809965 R forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein complement(2809636..2809965) Escherichia coli E24377A 5587068 YP_001463852.1 CDS iscU NC_009801.1 2809976 2810362 R identified by match to protein family HMM PF01592; match to protein family HMM TIGR01999; scaffold protein complement(2809976..2810362) Escherichia coli E24377A 5586354 YP_001463853.1 CDS iscS NC_009801.1 2810390 2811604 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(2810390..2811604) Escherichia coli E24377A 5586952 YP_001463854.1 CDS iscR NC_009801.1 2811716 2812204 R regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR complement(2811716..2812204) Escherichia coli E24377A 5589754 YP_001463855.1 CDS EcE24377A_2817 NC_009801.1 2812505 2813242 R identified by match to protein family HMM PF00588; match to protein family HMM TIGR00050; RNA methyltransferase complement(2812505..2813242) Escherichia coli E24377A 5589450 YP_001463856.1 CDS suhB NC_009801.1 2813361 2814164 D identified by similarity to SP:P0ADG4; match to protein family HMM PF00459; inositol monophosphatase 2813361..2814164 Escherichia coli E24377A 5587139 YP_001463857.1 CDS EcE24377A_2819 NC_009801.1 2814309 2815163 D hypothetical protein 2814309..2815163 Escherichia coli E24377A 5590675 YP_001463858.1 CDS csiE NC_009801.1 2815354 2816634 D identified by match to protein family HMM PF00874; stationary phase inducible protein CsiE 2815354..2816634 Escherichia coli E24377A 5587311 YP_001463859.1 CDS hcaT NC_009801.1 2816626 2817765 R transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter complement(2816626..2817765) Escherichia coli E24377A 5589682 YP_001463860.1 CDS hcaR NC_009801.1 2817925 2818815 R activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional regulator HcaR complement(2817925..2818815) Escherichia coli E24377A 5587894 YP_001463861.1 CDS hcaF NC_009801.1 2820309 2820827 D identified by similarity to SP:Q47140; match to protein family HMM PF00866; 3-phenylpropionate dioxygenase subunit beta 2820309..2820827 Escherichia coli E24377A 5589475 YP_001463862.1 CDS hcaC NC_009801.1 2820827 2821147 D identified by similarity to SP:P0ABW2; match to protein family HMM PF00355; 3-phenylpropionate dioxygenase ferredoxin subunit 2820827..2821147 Escherichia coli E24377A 5589990 YP_001463863.1 CDS hcaB NC_009801.1 2821144 2821956 D Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase 2821144..2821956 Escherichia coli E24377A 5587581 YP_001463864.1 CDS hcaD NC_009801.1 2821966 2823168 D identified by similarity to SP:P77650; match to protein family HMM PF00070; match to protein family HMM PF07992; phenylpropionate dioxygenase ferredoxin reductase subunit 2821966..2823168 Escherichia coli E24377A 5589044 YP_001463865.1 CDS EcE24377A_2828 NC_009801.1 2823265 2823687 D identified by match to protein family HMM PF07681; hypothetical protein 2823265..2823687 Escherichia coli E24377A 5588922 YP_001463866.1 CDS EcE24377A_2829 NC_009801.1 2823735 2824607 R identified by match to protein family HMM PF01263; aldose 1-epimerase complement(2823735..2824607) Escherichia coli E24377A 5589540 YP_001463867.1 CDS EcE24377A_2830 NC_009801.1 2824619 2825713 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; zinc-binding dehydrogenase oxidoreductase complement(2824619..2825713) Escherichia coli E24377A 5590616 YP_001463868.1 CDS EcE24377A_2831 NC_009801.1 2825746 2826744 R identified by match to protein family HMM PF02653; sugar ABC transporter permease complement(2825746..2826744) Escherichia coli E24377A 5587735 YP_001463869.1 CDS EcE24377A_2832 NC_009801.1 2826769 2828280 R yphE; identified by match to protein family HMM PF00005; sugar ABC transporter ATP-binding protein complement(2826769..2828280) Escherichia coli E24377A 5587652 YP_001463870.1 CDS EcE24377A_2833 NC_009801.1 2828303 2829247 R identified by match to protein family HMM PF00532; sugar ABC transporter periplasmic sugar-binding protein complement(2828303..2829247) Escherichia coli E24377A 5588395 YP_001463871.1 CDS EcE24377A_2834 NC_009801.1 2829383 2832757 R identified by match to protein family HMM PF00515; match to protein family HMM PF07719; hypothetical protein complement(2829383..2832757) Escherichia coli E24377A 5587308 YP_001463872.1 CDS EcE24377A_2835 NC_009801.1 2832782 2833975 D identified by match to protein family HMM PF00480; ROK family protein 2832782..2833975 Escherichia coli E24377A 5587128 YP_001463873.1 CDS glyA NC_009801.1 2834039 2835292 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(2834039..2835292) Escherichia coli E24377A 5587015 YP_001463874.1 CDS hmp NC_009801.1 2835620 2836810 D flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2835620..2836810 Escherichia coli E24377A 5588417 YP_001463875.1 CDS glnB NC_009801.1 2836855 2837193 R indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 complement(2836855..2837193) Escherichia coli E24377A 5588143 YP_001463876.1 CDS EcE24377A_2839 NC_009801.1 2837254 2838588 R identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728; sigma-54 dependent response regulator complement(2837254..2838588) Escherichia coli E24377A 5586224 YP_001463877.1 CDS EcE24377A_2840 NC_009801.1 2838578 2839297 R hypothetical protein complement(2838578..2839297) Escherichia coli E24377A 5588572 YP_001463878.1 CDS EcE24377A_2841 NC_009801.1 2839456 2840838 R identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase complement(2839456..2840838) Escherichia coli E24377A 5588836 YP_001463879.1 CDS purL NC_009801.1 2841459 2845346 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase complement(2841459..2845346) Escherichia coli E24377A 5590665 YP_001463880.1 CDS EcE24377A_2844 NC_009801.1 2845742 2847160 D YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 2845742..2847160 Escherichia coli E24377A 5587864 YP_001463881.1 CDS tadA NC_009801.1 2847157 2847693 R identified by similarity to SP:P68398; match to protein family HMM PF00383; tRNA-specific adenosine deaminase complement(2847157..2847693) Escherichia coli E24377A 5588293 YP_001463882.1 CDS yhfB NC_009801.1 2847718 2848353 R identified by match to protein family HMM TIGR01545; hypothetical protein complement(2847718..2848353) Escherichia coli E24377A 5588510 YP_001463883.1 CDS EcE24377A_2846 NC_009801.1 2848562 2849410 D identified by match to protein family HMM PF01380; match to protein family HMM PF01418; DNA-binding transcriptional regulator 2848562..2849410 Escherichia coli E24377A 5589788 YP_001463884.1 CDS EcE24377A_2847 NC_009801.1 2849466 2849726 D identified by match to protein family HMM PF00037; 4Fe-4S ferredoxin 2849466..2849726 Escherichia coli E24377A 5590249 YP_001463885.1 CDS EcE24377A_2848 NC_009801.1 2849920 2850018 R identified by glimmer; hypothetical protein complement(2849920..2850018) Escherichia coli E24377A 5589657 YP_001463886.1 CDS acpS NC_009801.1 2850420 2850800 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(2850420..2850800) Escherichia coli E24377A 5586550 YP_001463887.1 CDS pdxJ NC_009801.1 2850800 2851531 R involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase complement(2850800..2851531) Escherichia coli E24377A 5590452 YP_001463888.1 CDS recO NC_009801.1 2851543 2852271 R involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO complement(2851543..2852271) Escherichia coli E24377A 5585926 YP_001463889.1 CDS era NC_009801.1 2852283 2853188 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(2852283..2853188) Escherichia coli E24377A 5587943 YP_001463890.1 CDS rnc NC_009801.1 2853185 2853865 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(2853185..2853865) Escherichia coli E24377A 5585969 YP_001463891.1 CDS lepB NC_009801.1 2854137 2855111 R catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I complement(2854137..2855111) Escherichia coli E24377A 5589777 YP_001463892.1 CDS lepA NC_009801.1 2855127 2856926 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(2855127..2856926) Escherichia coli E24377A 5589193 YP_001463893.1 CDS rseC NC_009801.1 2857124 2857603 R involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC complement(2857124..2857603) Escherichia coli E24377A 5586176 YP_001463894.1 CDS rseB NC_009801.1 2857600 2858556 R periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE complement(2857600..2858556) Escherichia coli E24377A 5587495 YP_001463895.1 CDS rseA NC_009801.1 2858556 2859206 R identified by match to protein family HMM PF03872; match to protein family HMM PF03873; anti-RNA polymerase sigma factor SigE complement(2858556..2859206) Escherichia coli E24377A 5589516 YP_001463896.1 CDS rpoE NC_009801.1 2859239 2859814 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(2859239..2859814) Escherichia coli E24377A 5589246 YP_001463897.1 CDS EcE24377A_2860 NC_009801.1 2860027 2860134 R identified by glimmer; hypothetical protein complement(2860027..2860134) Escherichia coli E24377A 5589850 YP_001463898.1 CDS nadB NC_009801.1 2860222 2861844 D catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2860222..2861844 Escherichia coli E24377A 5589763 YP_001463899.1 CDS EcE24377A_2861 NC_009801.1 2861829 2862566 R identified by match to protein family HMM PF05175; methyltransferase complement(2861829..2862566) Escherichia coli E24377A 5589589 YP_001463900.1 CDS srmB NC_009801.1 2862698 2864032 D facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2862698..2864032 Escherichia coli E24377A 5589061 YP_001463901.1 CDS EcE24377A_2864 NC_009801.1 2864065 2864946 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(2864065..2864946) Escherichia coli E24377A 5586495 YP_001463902.1 CDS EcE24377A_2865 NC_009801.1 2865049 2865636 D identified by match to protein family HMM PF01810; neutral amino-acid efflux protein 2865049..2865636 Escherichia coli E24377A 5589675 YP_001463903.1 CDS grcA NC_009801.1 2865691 2866074 R stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA complement(2865691..2866074) Escherichia coli E24377A 5586198 YP_001463904.1 CDS ung NC_009801.1 2866379 2867068 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2866379..2867068 Escherichia coli E24377A 5586141 YP_001463905.1 CDS EcE24377A_2868 NC_009801.1 2867116 2868153 R identified by match to protein family HMM PF00588; match to protein family HMM PF08032; methyltransferase complement(2867116..2868153) Escherichia coli E24377A 5590392 YP_001463906.1 CDS EcE24377A_2869 NC_009801.1 2868360 2868779 D identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 2 2868360..2868779 Escherichia coli E24377A 5588576 YP_001463907.1 CDS EcE24377A_2870 NC_009801.1 2868848 2869546 D identified by match to protein family HMM PF03942; DTW domain-containing protein 2868848..2869546 Escherichia coli E24377A 5590686 YP_001463908.1 CDS EcE24377A_2871 NC_009801.1 2869578 2872238 D identified by similarity to GB:BAA07751.1; match to protein family HMM PF00583; match to protein family HMM PF02629; CoA-binding domain/acetyltransferase domain-containing protein 2869578..2872238 Escherichia coli E24377A 5585908 YP_001463909.1 CDS pssA NC_009801.1 2872352 2873707 D catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 2872352..2873707 Escherichia coli E24377A 5588418 YP_001463910.1 CDS EcE24377A_2874 NC_009801.1 2873753 2874076 D hypothetical protein 2873753..2874076 Escherichia coli E24377A 5586767 YP_001463911.1 CDS kgtP NC_009801.1 2874073 2875371 R identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883; alpha-ketoglutarate transporter complement(2874073..2875371) Escherichia coli E24377A 5588134 YP_001463912.1 CDS EcE24377A_2877 NC_009801.1 2881051 2881185 D identified by similarity to GB:AAN81562.1; hypothetical protein 2881051..2881185 Escherichia coli E24377A 5590143 YP_001463913.1 CDS clpB NC_009801.1 2881227 2883800 R identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; protein disaggregation chaperone complement(2881227..2883800) Escherichia coli E24377A 5589729 YP_001463914.1 CDS EcE24377A_2879 NC_009801.1 2883930 2884661 R identified by similarity to PDB:1XAF_A; match to protein family HMM PF02578; match to protein family HMM TIGR00726; hypothetical protein complement(2883930..2884661) Escherichia coli E24377A 5589481 YP_001463915.1 CDS rluD NC_009801.1 2884658 2885638 R responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D complement(2884658..2885638) Escherichia coli E24377A 5588757 YP_001463916.1 CDS EcE24377A_2881 NC_009801.1 2885773 2886510 D with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 2885773..2886510 Escherichia coli E24377A 5589011 YP_001463917.1 CDS EcE24377A_2882 NC_009801.1 2886781 2887122 D associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 2886781..2887122 Escherichia coli E24377A 5589528 YP_001463918.1 CDS pheA NC_009801.1 2887372 2888532 D catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 2887372..2888532 Escherichia coli E24377A 5586166 YP_001463919.1 CDS tyrA NC_009801.1 2888575 2889696 R catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase complement(2888575..2889696) Escherichia coli E24377A 5587944 YP_001463920.1 CDS aroF NC_009801.1 2889707 2890777 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(2889707..2890777) Escherichia coli E24377A 5586036 YP_001463921.1 CDS EcE24377A_2886 NC_009801.1 2890987 2891352 D hypothetical protein 2890987..2891352 Escherichia coli E24377A 5588101 YP_001463922.1 CDS EcE24377A_2887 NC_009801.1 2891502 2892020 D identified by similarity to SP:P64548; hypothetical protein 2891502..2892020 Escherichia coli E24377A 5586608 YP_001463923.1 CDS EcE24377A_2888 NC_009801.1 2892013 2893236 D identified by match to protein family HMM PF00672; match to protein family HMM PF00990; match to protein family HMM TIGR00254; hypothetical protein 2892013..2893236 Escherichia coli E24377A 5590862 YP_001463924.1 CDS EcE24377A_2889 NC_009801.1 2893252 2893734 D identified by match to protein family HMM PF00691; outer membrane lipoprotein 2893252..2893734 Escherichia coli E24377A 5586717 YP_001463925.1 CDS rplS NC_009801.1 2893811 2894158 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(2893811..2894158) Escherichia coli E24377A 5586613 YP_001463926.1 CDS trmD NC_009801.1 2894200 2894967 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(2894200..2894967) Escherichia coli E24377A 5590093 YP_001463927.1 CDS rimM NC_009801.1 2894998 2895546 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(2894998..2895546) Escherichia coli E24377A 5590195 YP_001463928.1 CDS rpsP NC_009801.1 2895565 2895813 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(2895565..2895813) Escherichia coli E24377A 5587275 YP_001463929.1 CDS ffh NC_009801.1 2896062 2897423 R with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein complement(2896062..2897423) Escherichia coli E24377A 5590748 YP_001463930.1 CDS EcE24377A_2895 NC_009801.1 2897515 2898381 D identified by match to protein family HMM PF01578; cytochrome C assembly protein 2897515..2898381 Escherichia coli E24377A 5588105 YP_001463931.1 CDS EcE24377A_2896 NC_009801.1 2898426 2899688 D identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; hypothetical protein 2898426..2899688 Escherichia coli E24377A 5590334 YP_001463932.1 CDS EcE24377A_2897 NC_009801.1 2899811 2900416 D identified by similarity to GB:AAX66587.1; hypothetical protein 2899811..2900416 Escherichia coli E24377A 5587815 YP_001463933.1 CDS grpE NC_009801.1 2900451 2901041 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(2900451..2901041) Escherichia coli E24377A 5589579 YP_001463934.1 CDS ppnK NC_009801.1 2901164 2902042 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2901164..2902042 Escherichia coli E24377A 5589917 YP_001463935.1 CDS recN NC_009801.1 2902128 2903789 D identified by similarity to SP:P05824; match to protein family HMM PF02463; match to protein family HMM TIGR00634; recombination and repair protein 2902128..2903789 Escherichia coli E24377A 5590597 YP_001463936.1 CDS EcE24377A_2901 NC_009801.1 2903938 2904279 D identified by match to protein family HMM PF04355; hypothetical protein 2903938..2904279 Escherichia coli E24377A 5588983 YP_001463937.1 CDS EcE24377A_2902 NC_009801.1 2904341 2904631 R identified by similarity to SP:P52119; match to protein family HMM PF03658; hypothetical protein complement(2904341..2904631) Escherichia coli E24377A 5588032 YP_001463938.1 CDS EcE24377A_2903 NC_009801.1 2904621 2905058 R identified by match to protein family HMM PF03364; hypothetical protein complement(2904621..2905058) Escherichia coli E24377A 5588497 YP_001463939.1 CDS smpB NC_009801.1 2905229 2905711 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 2905229..2905711 Escherichia coli E24377A 5589007 YP_001463940.1 CDS EcE24377A_2905 NC_009801.1 2906374 2907684 D identified by match to protein family HMM PF00589; phage integrase 2906374..2907684 Escherichia coli E24377A 5586135 YP_001463941.1 CDS EcE24377A_2906 NC_009801.1 2907967 2909523 D identified by match to protein family HMM PF00239; match to protein family HMM PF07508; resolvase site-specific recombinase 2907967..2909523 Escherichia coli E24377A 5588398 YP_001463942.1 CDS EcE24377A_2907 NC_009801.1 2909513 2910409 D identified by match to protein family HMM PF02195; ParB family protein 2909513..2910409 Escherichia coli E24377A 5588533 YP_001463943.1 CDS EcE24377A_2908 NC_009801.1 2910406 2911302 D identified by match to protein family HMM PF07506; repB plasmid partitioning protein 2910406..2911302 Escherichia coli E24377A 5588555 YP_001463944.1 CDS EcE24377A_2909 NC_009801.1 2912713 2914260 D identified by match to protein family HMM PF02384; N4/N6-methyltransferase 2912713..2914260 Escherichia coli E24377A 5586861 YP_001463945.1 CDS EcE24377A_2910 NC_009801.1 2914257 2915378 D identified by match to protein family HMM PF01420; type I restriction-modification system subunit S 2914257..2915378 Escherichia coli E24377A 5589342 YP_001463946.1 CDS EcE24377A_2911 NC_009801.1 2915437 2918676 D identified by match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM TIGR00348; HsdR family type I site-specific deoxyribonuclease 2915437..2918676 Escherichia coli E24377A 5586661 YP_001463947.1 CDS EcE24377A_2912 NC_009801.1 2919333 2920304 D identified by similarity to GB:AAO54619.1; hypothetical protein 2919333..2920304 Escherichia coli E24377A 5587314 YP_001463948.1 CDS EcE24377A_2913 NC_009801.1 2920734 2921720 D identified by glimmer; hypothetical protein 2920734..2921720 Escherichia coli E24377A 5586543 YP_001463949.1 CDS EcE24377A_2914 NC_009801.1 2922076 2922516 D identified by glimmer; hypothetical protein 2922076..2922516 Escherichia coli E24377A 5590647 YP_001463950.1 CDS EcE24377A_2916 NC_009801.1 2922532 2923476 D identified by glimmer; hypothetical protein 2922532..2923476 Escherichia coli E24377A 5590210 YP_001463951.1 CDS EcE24377A_2915 NC_009801.1 2922835 2923002 R identified by glimmer; hypothetical protein complement(2922835..2923002) Escherichia coli E24377A 5587961 YP_001463952.1 CDS EcE24377A_2917 NC_009801.1 2923654 2924058 D identified by similarity to GB:CAG73977.1; hypothetical protein 2923654..2924058 Escherichia coli E24377A 5586500 YP_001463953.1 CDS EcE24377A_2918 NC_009801.1 2924064 2925278 D identified by match to protein family HMM PF03432; relaxase/mobilization nuclease domain-containing protein 2924064..2925278 Escherichia coli E24377A 5589965 YP_001463954.1 CDS EcE24377A_2919 NC_009801.1 2925789 2926175 D lipoprotein 2925789..2926175 Escherichia coli E24377A 5590357 YP_001463955.1 CDS EcE24377A_2920 NC_009801.1 2926202 2926390 D lipoprotein 2926202..2926390 Escherichia coli E24377A 5587915 YP_001463956.1 CDS EcE24377A_2921 NC_009801.1 2926464 2927636 D identified by similarity to SP:P15025; match to protein family HMM PF00665; IS21 family transposase 2926464..2927636 Escherichia coli E24377A 5587658 YP_001463957.1 CDS EcE24377A_2922 NC_009801.1 2927636 2928430 D identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein 2927636..2928430 Escherichia coli E24377A 5588537 YP_001463958.1 CDS EcE24377A_2923 NC_009801.1 2928788 2929213 R identified by similarity to GB:CAG73974.1; hypothetical protein complement(2928788..2929213) Escherichia coli E24377A 5588939 YP_001463959.1 CDS EcE24377A_2924 NC_009801.1 2930208 2930771 D identified by similarity to GB:AAS55464.1; hypothetical protein 2930208..2930771 Escherichia coli E24377A 5589758 YP_001463960.1 CDS EcE24377A_2925 NC_009801.1 2932129 2932983 R hypothetical protein complement(2932129..2932983) Escherichia coli E24377A 5589294 YP_001463961.1 CDS EcE24377A_2927 NC_009801.1 2933741 2934733 D identified by glimmer; hypothetical protein 2933741..2934733 Escherichia coli E24377A 5590756 YP_001463962.1 CDS EcE24377A_2926 NC_009801.1 2933852 2934004 R identified by glimmer; hypothetical protein complement(2933852..2934004) Escherichia coli E24377A 5586115 YP_001463963.1 CDS EcE24377A_2928 NC_009801.1 2936009 2936974 D identified by similarity to GB:CAG74503.1; hypothetical protein 2936009..2936974 Escherichia coli E24377A 5587197 YP_001463964.1 CDS EcE24377A_2929 NC_009801.1 2937655 2937981 R identified by glimmer; hypothetical protein complement(2937655..2937981) Escherichia coli E24377A 5587534 YP_001463965.1 CDS EcE24377A_2931 NC_009801.1 2940350 2940739 D identified by match to protein family HMM PF01527; IS66 family orf1 2940350..2940739 Escherichia coli E24377A 5586850 YP_001463966.1 CDS EcE24377A_2932 NC_009801.1 2940736 2941083 D identified by match to protein family HMM PF05717; IS66 family orf2 2940736..2941083 Escherichia coli E24377A 5586187 YP_001463967.1 CDS EcE24377A_2937 NC_009801.1 2946921 2948762 D identified by match to protein family HMM PF00128; alpha amylase 2946921..2948762 Escherichia coli E24377A 5589255 YP_001463968.1 CDS EcE24377A_2938 NC_009801.1 2948901 2949173 D identified by similarity to GB:AAP18006.1; hypothetical protein 2948901..2949173 Escherichia coli E24377A 5589932 YP_001463969.1 CDS EcE24377A_2939 NC_009801.1 2949509 2950486 D in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 2949509..2950486 Escherichia coli E24377A 5589961 YP_001463970.1 CDS EcE24377A_2940 NC_009801.1 2950505 2951773 D catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 2950505..2951773 Escherichia coli E24377A 5589631 YP_001463971.1 CDS gabD NC_009801.1 2951796 2953244 D catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 2951796..2953244 Escherichia coli E24377A 5588281 YP_001463972.1 CDS gabT2 NC_009801.1 2953258 2954538 D catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 2953258..2954538 Escherichia coli E24377A 5587683 YP_001463973.1 CDS gabP NC_009801.1 2954776 2956176 D identified by match to protein family HMM PF00324; match to protein family HMM TIGR01773; gamma-aminobutyrate transporter 2954776..2956176 Escherichia coli E24377A 5588573 YP_001463974.1 CDS csiR NC_009801.1 2956197 2956859 D regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 2956197..2956859 Escherichia coli E24377A 5589196 YP_001463975.1 CDS EcE24377A_2945 NC_009801.1 2956860 2957309 R identified by match to protein family HMM PF01476; match to protein family HMM PF04972; LysM domain/BON superfamily protein complement(2956860..2957309) Escherichia coli E24377A 5588020 YP_001463976.1 CDS EcE24377A_2946 NC_009801.1 2957393 2957551 R identified by similarity to GB:AAV78517.1; match to protein family HMM PF01679; hypothetical protein complement(2957393..2957551) Escherichia coli E24377A 5590506 YP_001463977.1 CDS EcE24377A_2947 NC_009801.1 2957734 2958033 D identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 2957734..2958033 Escherichia coli E24377A 5589983 YP_001463978.1 CDS EcE24377A_2948 NC_009801.1 2958043 2958567 D identified by similarity to SP:P55734; inner membrane protein 2958043..2958567 Escherichia coli E24377A 5590858 YP_001463979.1 CDS stpA NC_009801.1 2958614 2959018 R identified by similarity to SP:P0ACG3; match to protein family HMM PF00816; DNA binding protein complement(2958614..2959018) Escherichia coli E24377A 5587195 YP_001463980.1 CDS EcE24377A_2950 NC_009801.1 2959432 2959560 D identified by glimmer; hypothetical protein 2959432..2959560 Escherichia coli E24377A 5590127 YP_001463981.1 CDS EcE24377A_2951 NC_009801.1 2959686 2960135 D identified by similarity to SP:P64553; match to protein family HMM PF06610; hypothetical protein 2959686..2960135 Escherichia coli E24377A 5586794 YP_001463982.1 CDS EcE24377A_2952 NC_009801.1 2960172 2960516 R hypothetical protein complement(2960172..2960516) Escherichia coli E24377A 5590257 YP_001463983.1 CDS EcE24377A_2953 NC_009801.1 2960668 2960997 D identified by similarity to GB:AAL21687.1; match to protein family HMM PF05957; hypothetical protein 2960668..2960997 Escherichia coli E24377A 5587703 YP_001463984.1 CDS nrdI NC_009801.1 2961487 2961897 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 2961487..2961897 Escherichia coli E24377A 5586427 YP_001463985.1 CDS nrdE NC_009801.1 2961870 2964014 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2961870..2964014 Escherichia coli E24377A 5587360 YP_001463986.1 CDS nrdF NC_009801.1 2964024 2964983 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 2964024..2964983 Escherichia coli E24377A 5590028 YP_001463987.1 CDS proV NC_009801.1 2965338 2966540 D with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 2965338..2966540 Escherichia coli E24377A 5588742 YP_001463988.1 CDS proW NC_009801.1 2966533 2967597 D with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 2966533..2967597 Escherichia coli E24377A 5588415 YP_001463989.1 CDS proX NC_009801.1 2967655 2968647 D with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 2967655..2968647 Escherichia coli E24377A 5590520 YP_001463990.1 CDS EcE24377A_2961 NC_009801.1 2968651 2968746 R identified by glimmer; hypothetical protein complement(2968651..2968746) Escherichia coli E24377A 5587418 YP_001463991.1 CDS EcE24377A_2962 NC_009801.1 2968679 2968843 R identified by glimmer; hypothetical protein complement(2968679..2968843) Escherichia coli E24377A 5589595 YP_001463992.1 CDS EcE24377A_2963 NC_009801.1 2968747 2968857 R identified by glimmer; hypothetical protein complement(2968747..2968857) Escherichia coli E24377A 5590188 YP_001463993.1 CDS EcE24377A_2964 NC_009801.1 2968938 2970122 D identified by match to protein family HMM PF07690; major facilitator family transporter 2968938..2970122 Escherichia coli E24377A 5586494 YP_001463994.1 CDS EcE24377A_2965 NC_009801.1 2970246 2970983 D identified by match to protein family HMM PF03591; branched chain amino acid ABC transporter 2970246..2970983 Escherichia coli E24377A 5586668 YP_001463995.1 CDS EcE24377A_2966 NC_009801.1 2970973 2971308 D identified by similarity to GB:AAZ89437.1; hypothetical protein 2970973..2971308 Escherichia coli E24377A 5590690 YP_001463996.1 CDS mprA NC_009801.1 2971399 2971929 D DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 2971399..2971929 Escherichia coli E24377A 5588752 YP_001463997.1 CDS emrA NC_009801.1 2972056 2973228 D identified by match to protein family HMM PF00529; match to protein family HMM TIGR00998; multidrug resistance protein A 2972056..2973228 Escherichia coli E24377A 5589401 YP_001463998.1 CDS emrB NC_009801.1 2973245 2974783 D identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; multidrug resistance protein B 2973245..2974783 Escherichia coli E24377A 5586679 YP_001463999.1 CDS luxS NC_009801.1 2974847 2975362 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(2974847..2975362) Escherichia coli E24377A 5587279 YP_001464000.1 CDS gshA NC_009801.1 2975512 2977068 R involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase complement(2975512..2977068) Escherichia coli E24377A 5588400 YP_001464001.1 CDS EcE24377A_2972 NC_009801.1 2977141 2977569 R hypothetical protein complement(2977141..2977569) Escherichia coli E24377A 5587742 YP_001464002.1 CDS EcE24377A_2973 NC_009801.1 2977566 2978132 R YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase complement(2977566..2978132) Escherichia coli E24377A 5589860 YP_001464003.1 CDS csrA NC_009801.1 2979455 2979640 R affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator complement(2979455..2979640) Escherichia coli E24377A 5590395 YP_001464004.1 CDS alaS NC_009801.1 2979875 2982505 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(2979875..2982505) Escherichia coli E24377A 5587731 YP_001464005.1 CDS EcE24377A_2981 NC_009801.1 2982455 2982592 D identified by glimmer; hypothetical protein 2982455..2982592 Escherichia coli E24377A 5587750 YP_001464006.1 CDS recX NC_009801.1 2982633 2983133 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(2982633..2983133) Escherichia coli E24377A 5588337 YP_001464007.1 CDS recA NC_009801.1 2983376 2984437 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(2983376..2984437) Escherichia coli E24377A 5590486 YP_001464008.1 CDS EcE24377A_2984 NC_009801.1 2984517 2985014 R identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199; competence damage-inducible protein A complement(2984517..2985014) Escherichia coli E24377A 5586586 YP_001464009.1 CDS mltB NC_009801.1 2985159 2986244 R membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B complement(2985159..2986244) Escherichia coli E24377A 5588266 YP_001464010.1 CDS srlA NC_009801.1 2986500 2987063 D identified by match to protein family HMM PF03608; match to protein family HMM TIGR00821; PTS system glucitol/sorbitol-specific transporter subunit IIC 2986500..2987063 Escherichia coli E24377A 5587938 YP_001464011.1 CDS srlE NC_009801.1 2987060 2988019 D identified by match to protein family HMM PF03612; match to protein family HMM PF07663; match to protein family HMM TIGR00825; PTS system glucitol/sorbitol-specific transporter subunit IIB 2987060..2988019 Escherichia coli E24377A 5590868 YP_001464012.1 CDS srlB NC_009801.1 2988030 2988401 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 2988030..2988401 Escherichia coli E24377A 5590256 YP_001464013.1 CDS srlD NC_009801.1 2988406 2989185 D catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 2988406..2989185 Escherichia coli E24377A 5589333 YP_001464014.1 CDS gutM NC_009801.1 2989290 2989649 D regulator for glucitol utilization; DNA-binding transcriptional activator GutM 2989290..2989649 Escherichia coli E24377A 5586958 YP_001464015.1 CDS srlR NC_009801.1 2989716 2990489 D regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 2989716..2990489 Escherichia coli E24377A 5589228 YP_001464016.1 CDS gutQ NC_009801.1 2990482 2991447 D catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 2990482..2991447 Escherichia coli E24377A 5588744 YP_001464017.1 CDS norR NC_009801.1 2991444 2992958 R Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator complement(2991444..2992958) Escherichia coli E24377A 5587146 YP_001464018.1 CDS norV NC_009801.1 2993145 2994584 D detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 2993145..2994584 Escherichia coli E24377A 5590596 YP_001464019.1 CDS norW NC_009801.1 2994581 2995714 D catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 2994581..2995714 Escherichia coli E24377A 5588508 YP_001464020.1 CDS hypF NC_009801.1 2995842 2998094 R identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143; carbamoyltransferase HypF complement(2995842..2998094) Escherichia coli E24377A 5587796 YP_001464021.1 CDS EcE24377A_2997 NC_009801.1 2998247 2998774 R involved in electron transport from formate to hydrogen; electron transport protein HydN complement(2998247..2998774) Escherichia coli E24377A 5590213 YP_001464022.1 CDS EcE24377A_2998 NC_009801.1 2998752 2998919 R identified by glimmer; hypothetical protein complement(2998752..2998919) Escherichia coli E24377A 5587445 YP_001464023.1 CDS ascG NC_009801.1 2998923 2999936 R identified by similarity to SP:P24242; match to protein family HMM PF00356; match to protein family HMM PF00532; transcriptional regulator AscG complement(2998923..2999936) Escherichia coli E24377A 5589092 YP_001464024.1 CDS ascF NC_009801.1 3000193 3001650 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC 3000193..3001650 Escherichia coli E24377A 5590656 YP_001464025.1 CDS ascB NC_009801.1 3001659 3003083 D identified by similarity to SP:P24240; match to protein family HMM PF00232; cryptic 6-phospho-beta-glucosidase 3001659..3003083 Escherichia coli E24377A 5590198 YP_001464026.1 CDS EcE24377A_3002 NC_009801.1 3003251 3004231 R identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase complement(3003251..3004231) Escherichia coli E24377A 5590382 YP_001464027.1 CDS EcE24377A_3003 NC_009801.1 3004476 3004895 R identified by match to protein family HMM PF01381; helix-turn-helix DNA-binding domain-containing protein complement(3004476..3004895) Escherichia coli E24377A 5588099 YP_001464028.1 CDS EcE24377A_3004 NC_009801.1 3004966 3005721 R identified by similarity to GB:AAZ89467.1; hypothetical protein complement(3004966..3005721) Escherichia coli E24377A 5590527 YP_001464029.1 CDS hycI NC_009801.1 3005764 3006234 R involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease complement(3005764..3006234) Escherichia coli E24377A 5588488 YP_001464030.1 CDS EcE24377A_3006 NC_009801.1 3006227 3006637 R identified by match to protein family HMM PF07450; formate hydrogenlyase maturation protein complement(3006227..3006637) Escherichia coli E24377A 5590013 YP_001464031.1 CDS hycG NC_009801.1 3006634 3007401 R identified by similarity to SP:P16433; match to protein family HMM PF01058; formate hydrogenlyase subunit G complement(3006634..3007401) Escherichia coli E24377A 5586509 YP_001464032.1 CDS hycF NC_009801.1 3007401 3007943 R electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit complement(3007401..3007943) Escherichia coli E24377A 5586326 YP_001464033.1 CDS hycE NC_009801.1 3007953 3009662 R identified by similarity to SP:P16431; match to protein family HMM PF00329; match to protein family HMM PF00346; formate hydrogenlyase subunit E complement(3007953..3009662) Escherichia coli E24377A 5587579 YP_001464034.1 CDS hycD NC_009801.1 3009680 3010603 R identified by similarity to SP:P16430; match to protein family HMM PF00146; formate hydrogenlyase subunit D complement(3009680..3010603) Escherichia coli E24377A 5587751 YP_001464035.1 CDS hycC NC_009801.1 3010606 3012432 R catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 complement(3010606..3012432) Escherichia coli E24377A 5589278 YP_001464036.1 CDS hycB NC_009801.1 3012429 3013040 R identified by similarity to SP:P0AAK1; match to protein family HMM PF00037; formate hydrogenlyase subunit B complement(3012429..3013040) Escherichia coli E24377A 5587645 YP_001464037.1 CDS hycA NC_009801.1 3013165 3013626 R regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA complement(3013165..3013626) Escherichia coli E24377A 5589367 YP_001464038.1 CDS hypA NC_009801.1 3013838 3014188 D plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 3013838..3014188 Escherichia coli E24377A 5589124 YP_001464039.1 CDS hypB NC_009801.1 3014192 3015064 D GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 3014192..3015064 Escherichia coli E24377A 5588845 YP_001464040.1 CDS hypC NC_009801.1 3015055 3015327 D HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 3015055..3015327 Escherichia coli E24377A 5587147 YP_001464041.1 CDS hypD NC_009801.1 3015327 3016448 D identified by similarity to SP:P24192; match to protein family HMM PF01924; match to protein family HMM TIGR00075; hydrogenase expression/formation protein HypD 3015327..3016448 Escherichia coli E24377A 5589000 YP_001464042.1 CDS hypE NC_009801.1 3016445 3017455 D identified by similarity to SP:P24193; match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR02124; hydrogenase expression/formation protein HypE 3016445..3017455 Escherichia coli E24377A 5590033 YP_001464043.1 CDS fhlA NC_009801.1 3017529 3019607 D identified by similarity to SP:P19323; match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728; formate hydrogenlyase transcriptional activator 3017529..3019607 Escherichia coli E24377A 5589476 YP_001464044.1 CDS EcE24377A_3020 NC_009801.1 3019644 3019997 R identified by similarity to SP:P25728; hypothetical protein complement(3019644..3019997) Escherichia coli E24377A 5588037 YP_001464045.1 CDS EcE24377A_3021 NC_009801.1 3020717 3022696 R identified by glimmer; hypothetical protein complement(3020717..3022696) Escherichia coli E24377A 5590189 YP_001464046.1 CDS EcE24377A_3022 NC_009801.1 3023045 3023803 D identified by glimmer; hypothetical protein 3023045..3023803 Escherichia coli E24377A 5588818 YP_001464047.1 CDS EcE24377A_3023 NC_009801.1 3024015 3025631 D identified by glimmer; hypothetical protein 3024015..3025631 Escherichia coli E24377A 5589858 YP_001464048.1 CDS EcE24377A_3024 NC_009801.1 3026474 3026773 D identified by match to protein family HMM PF01527; IS3, transposase orfA 3026474..3026773 Escherichia coli E24377A 5590353 YP_001464049.1 CDS EcE24377A_3025 NC_009801.1 3026770 3027636 D identified by similarity to SP:P05822; match to protein family HMM PF00665; IS3, transposase orfB 3026770..3027636 Escherichia coli E24377A 5587237 YP_001464050.1 CDS EcE24377A_3026 NC_009801.1 3028075 3030093 R hypothetical protein complement(3028075..3030093) Escherichia coli E24377A 5588435 YP_001464051.1 CDS EcE24377A_3028 NC_009801.1 3031348 3032808 R identified by match to protein family HMM PF00589; phage integrase complement(3031348..3032808) Escherichia coli E24377A 5586943 YP_001464052.1 CDS mutS NC_009801.1 3032953 3035535 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3032953..3035535 Escherichia coli E24377A 5587055 YP_001464053.1 CDS pphB NC_009801.1 3035641 3036297 D identified by match to protein family HMM PF00149; serine/threonine-specific protein phosphatase 2 3035641..3036297 Escherichia coli E24377A 5590747 YP_001464054.1 CDS EcE24377A_3032 NC_009801.1 3036348 3037115 R identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; DeoR family transcriptional regulator complement(3036348..3037115) Escherichia coli E24377A 5589894 YP_001464055.1 CDS EcE24377A_3033 NC_009801.1 3037311 3038219 D identified by match to protein family HMM PF03446; 6-phosphogluconate dehydrogenase 3037311..3038219 Escherichia coli E24377A 5588027 YP_001464056.1 CDS EcE24377A_3034 NC_009801.1 3038216 3039478 D identified by match to protein family HMM PF07005; hypothetical protein 3038216..3039478 Escherichia coli E24377A 5587096 YP_001464057.1 CDS EcE24377A_3035 NC_009801.1 3039475 3040113 D identified by match to protein family HMM PF00596; aldolase 3039475..3040113 Escherichia coli E24377A 5589854 YP_001464058.1 CDS EcE24377A_3036 NC_009801.1 3040118 3040894 D identified by match to protein family HMM PF01261; hypothetical protein 3040118..3040894 Escherichia coli E24377A 5586094 YP_001464059.1 CDS EcE24377A_3037 NC_009801.1 3040983 3042347 D member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; inner membrane permease YgbN 3040983..3042347 Escherichia coli E24377A 5587634 YP_001464060.1 CDS kpdD NC_009801.1 3042387 3042623 R identified by similarity to GB:AAY57856.1; 4-hydroxybenzoate decarboxylase subunit D complement(3042387..3042623) Escherichia coli E24377A 5587355 YP_001464061.1 CDS kpdC NC_009801.1 3042634 3044061 R identified by similarity to GB:AAY57855.1; match to protein family HMM PF01977; match to protein family HMM TIGR00148; 4-hydroxybenzoate decarboxylase subunit C complement(3042634..3044061) Escherichia coli E24377A 5590877 YP_001464062.1 CDS kpdB NC_009801.1 3044061 3044654 R identified by similarity to GB:AAY57854.1; match to protein family HMM PF02441; match to protein family HMM TIGR00421; 4-hydroxybenzoate decarboxylase subunit B complement(3044061..3044654) Escherichia coli E24377A 5587557 YP_001464063.1 CDS EcE24377A_3041 NC_009801.1 3044801 3045208 D identified by match to protein family HMM PF01047; MarR family transcriptional regulator 3044801..3045208 Escherichia coli E24377A 5590671 YP_001464064.1 CDS rpoS NC_009801.1 3045329 3046321 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS complement(3045329..3046321) Escherichia coli E24377A 5586460 YP_001464065.1 CDS nlpD NC_009801.1 3046384 3047523 R outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD complement(3046384..3047523) Escherichia coli E24377A 5587167 YP_001464066.1 CDS pcm NC_009801.1 3047663 3048289 R catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase complement(3047663..3048289) Escherichia coli E24377A 5586309 YP_001464067.1 CDS surE NC_009801.1 3048283 3049044 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(3048283..3049044) Escherichia coli E24377A 5590813 YP_001464068.1 CDS truD NC_009801.1 3049025 3050074 R catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D complement(3049025..3050074) Escherichia coli E24377A 5586518 YP_001464069.1 CDS ispF NC_009801.1 3050071 3050550 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(3050071..3050550) Escherichia coli E24377A 5590724 YP_001464070.1 CDS ispD NC_009801.1 3050550 3051260 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(3050550..3051260) Escherichia coli E24377A 5586078 YP_001464071.1 CDS ftsB NC_009801.1 3051279 3051590 R forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB complement(3051279..3051590) Escherichia coli E24377A 5588394 YP_001464072.1 CDS EcE24377A_3050 NC_009801.1 3051784 3052107 R identified by similarity to GB:AAG42462.1; hypothetical protein complement(3051784..3052107) Escherichia coli E24377A 5587236 YP_001464073.1 CDS cysC NC_009801.1 3052157 3052762 R converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase complement(3052157..3052762) Escherichia coli E24377A 5589634 YP_001464074.1 CDS cysN NC_009801.1 3052762 3054189 R may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 complement(3052762..3054189) Escherichia coli E24377A 5590781 YP_001464075.1 CDS cysD NC_009801.1 3054191 3055099 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(3054191..3055099) Escherichia coli E24377A 5588993 YP_001464076.1 CDS iap NC_009801.1 3055351 3056388 D catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase 3055351..3056388 Escherichia coli E24377A 5587431 YP_001464077.1 CDS cas1 NC_009801.1 3057621 3058541 R identified by match to protein family HMM TIGR00287; CRISPR-associated Cas1 family protein complement(3057621..3058541) Escherichia coli E24377A 5589688 YP_001464078.1 CDS cse3 NC_009801.1 3058538 3059188 R identified by match to protein family HMM PF08798; match to protein family HMM TIGR01907; CRISPR-associated Cse3 family protein complement(3058538..3059188) Escherichia coli E24377A 5587602 YP_001464079.1 CDS cas5e NC_009801.1 3059170 3059916 R identified by match to protein family HMM TIGR01868; match to protein family HMM TIGR02593; CRISPR-associated Cas5 family protein complement(3059170..3059916) Escherichia coli E24377A 5588425 YP_001464080.1 CDS cse4 NC_009801.1 3059927 3060982 R identified by match to protein family HMM TIGR01869; CRISPR-associated Cse4 family protein complement(3059927..3060982) Escherichia coli E24377A 5589843 YP_001464081.1 CDS cse2 NC_009801.1 3060994 3061530 R identified by match to protein family HMM TIGR02548; CRISPR-associated Cse2 family protein complement(3060994..3061530) Escherichia coli E24377A 5589047 YP_001464082.1 CDS cse1 NC_009801.1 3061527 3063089 R identified by match to protein family HMM TIGR02547; CRISPR-associated Cse1 family protein complement(3061527..3063089) Escherichia coli E24377A 5590399 YP_001464083.1 CDS cas3 NC_009801.1 3063187 3065844 R identified by match to protein family HMM PF00271; match to protein family HMM TIGR01587; CRISPR-associated helicase Cas3 complement(3063187..3065844) Escherichia coli E24377A 5590841 YP_001464084.1 CDS cysH NC_009801.1 3066497 3067231 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(3066497..3067231) Escherichia coli E24377A 5589881 YP_001464085.1 CDS cysI NC_009801.1 3067305 3069017 R hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta complement(3067305..3069017) Escherichia coli E24377A 5589173 YP_001464086.1 CDS cysJ NC_009801.1 3069017 3070816 R catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha complement(3069017..3070816) Escherichia coli E24377A 5587243 YP_001464087.1 CDS queD NC_009801.1 3071132 3071497 D identified by match to protein family HMM PF01242; match to protein family HMM TIGR00039; match to protein family HMM TIGR03367; queuosine biosynthesis protein QueD 3071132..3071497 Escherichia coli E24377A 5589497 YP_001464088.1 CDS EcE24377A_3068 NC_009801.1 3071575 3072846 D identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486; match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase 3071575..3072846 Escherichia coli E24377A 5587922 YP_001464089.1 CDS EcE24377A_3069 NC_009801.1 3072837 3073097 D ferredoxin 3072837..3073097 Escherichia coli E24377A 5589209 YP_001464090.1 CDS EcE24377A_3070 NC_009801.1 3073114 3073689 D identified by match to protein family HMM PF04309; glycerol-3-phosphate responsive antiterminator (mRNA-binding), glpp 3073114..3073689 Escherichia coli E24377A 5586064 YP_001464091.1 CDS EcE24377A_3071 NC_009801.1 3073837 3074697 R identified by match to protein family HMM PF00766; electron transfer flavoprotein complement(3073837..3074697) Escherichia coli E24377A 5585996 YP_001464092.1 CDS EcE24377A_3072 NC_009801.1 3074694 3075473 R identified by match to protein family HMM PF01012; electron transfer flavoprotein complement(3074694..3075473) Escherichia coli E24377A 5589473 YP_001464093.1 CDS EcE24377A_3073 NC_009801.1 3075451 3076788 R identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator family transporter complement(3075451..3076788) Escherichia coli E24377A 5587636 YP_001464094.1 CDS EcE24377A_3074 NC_009801.1 3076882 3078336 R identified by match to protein family HMM PF01565; match to protein family HMM PF02913; FAD binding domain-containing protein complement(3076882..3078336) Escherichia coli E24377A 5588298 YP_001464095.1 CDS EcE24377A_3075 NC_009801.1 3078406 3079191 R ygcW; identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase complement(3078406..3079191) Escherichia coli E24377A 5589410 YP_001464096.1 CDS EcE24377A_3076 NC_009801.1 3079510 3080787 D identified by match to protein family HMM PF07690; major facilitator family transporter 3079510..3080787 Escherichia coli E24377A 5588315 YP_001464097.1 CDS EcE24377A_3077 NC_009801.1 3080814 3082292 D ygcE; identified by match to protein family HMM PF00370; match to protein family HMM PF02782; carbohydrate kinase, FGGY family protein 3080814..3082292 Escherichia coli E24377A 5585931 YP_001464098.1 CDS EcE24377A_3080 NC_009801.1 3084824 3085495 R hypothetical protein complement(3084824..3085495) Escherichia coli E24377A 5587585 YP_001464099.1 CDS EcE24377A_3081 NC_009801.1 3085634 3085774 D identified by glimmer; hypothetical protein 3085634..3085774 Escherichia coli E24377A 5590151 YP_001464100.1 CDS EcE24377A_3082 NC_009801.1 3085788 3086660 D identified by match to protein family HMM PF04536; hypothetical protein 3085788..3086660 Escherichia coli E24377A 5588323 YP_001464101.1 CDS eno NC_009801.1 3086720 3088018 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(3086720..3088018) Escherichia coli E24377A 5587666 YP_001464102.1 CDS pyrG NC_009801.1 3088106 3089743 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(3088106..3089743) Escherichia coli E24377A 5590731 YP_001464103.1 CDS mazG NC_009801.1 3089971 3090762 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era; nucleoside triphosphate pyrophosphohydrolase complement(3089971..3090762) Escherichia coli E24377A 5589760 YP_001464104.1 CDS chpA NC_009801.1 3090833 3091168 R MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA complement(3090833..3091168) Escherichia coli E24377A 5588574 YP_001464105.1 CDS chpR NC_009801.1 3091168 3091416 R part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE complement(3091168..3091416) Escherichia coli E24377A 5588183 YP_001464106.1 CDS relA NC_009801.1 3091494 3093728 R (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase complement(3091494..3093728) Escherichia coli E24377A 5587853 YP_001464107.1 CDS rumA NC_009801.1 3093776 3095077 R in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase complement(3093776..3095077) Escherichia coli E24377A 5587757 YP_001464108.1 CDS barA NC_009801.1 3095134 3097890 D part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3095134..3097890 Escherichia coli E24377A 5590424 YP_001464109.1 CDS EcE24377A_3091 NC_009801.1 3098122 3099462 R identified by match to protein family HMM PF01188; match to protein family HMM TIGR03247; glucarate dehydratase complement(3098122..3099462) Escherichia coli E24377A 5587969 YP_001464110.1 CDS EcE24377A_3092 NC_009801.1 3099483 3100823 R identified by match to protein family HMM PF01188; match to protein family HMM PF02746; glucarate dehydratase complement(3099483..3100823) Escherichia coli E24377A 5589456 YP_001464111.1 CDS gudP NC_009801.1 3100825 3102177 R identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893; glucarate permease complement(3100825..3102177) Escherichia coli E24377A 5589645 YP_001464112.1 CDS EcE24377A_3094 NC_009801.1 3102612 3103061 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(3102612..3103061) Escherichia coli E24377A 5587690 YP_001464113.1 CDS truC NC_009801.1 3103079 3103861 R catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C complement(3103079..3103861) Escherichia coli E24377A 5590184 YP_001464114.1 CDS EcE24377A_3096 NC_009801.1 3103861 3104190 R identified by similarity to SP:Q46919; match to protein family HMM PF04287; hypothetical protein complement(3103861..3104190) Escherichia coli E24377A 5587316 YP_001464115.1 CDS EcE24377A_3097 NC_009801.1 3104812 3105357 R SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd complement(3104812..3105357) Escherichia coli E24377A 5588303 YP_001464116.1 CDS queF NC_009801.1 3105425 3106273 D catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3105425..3106273 Escherichia coli E24377A 5586719 YP_001464117.1 CDS EcE24377A_3098 NC_009801.1 3106212 3106304 R identified by glimmer; hypothetical protein complement(3106212..3106304) Escherichia coli E24377A 5590586 YP_001464118.1 CDS EcE24377A_3100 NC_009801.1 3106385 3107749 D identified by similarity to SP:P0ADS1; match to protein family HMM PF03641; hypothetical protein 3106385..3107749 Escherichia coli E24377A 5590678 YP_001464119.1 CDS EcE24377A_3101 NC_009801.1 3108306 3109595 D identified by match to protein family HMM TIGR00814; serine transporter family protein 3108306..3109595 Escherichia coli E24377A 5587902 YP_001464120.1 CDS sdaB NC_009801.1 3109653 3111020 D identified by similarity to SP:P16095; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; L-serine dehydratase 2 3109653..3111020 Escherichia coli E24377A 5587927 YP_001464121.1 CDS xni NC_009801.1 3111042 3111887 D has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 3111042..3111887 Escherichia coli E24377A 5587392 YP_001464122.1 CDS fucO NC_009801.1 3111942 3113090 R identified by match to protein family HMM PF00465; match to protein family HMM TIGR02638; L-1,2-propanediol oxidoreductase complement(3111942..3113090) Escherichia coli E24377A 5589169 YP_001464123.1 CDS fucA NC_009801.1 3113118 3113765 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(3113118..3113765) Escherichia coli E24377A 5587466 YP_001464124.1 CDS fucP NC_009801.1 3114312 3115628 D identified by match to protein family HMM PF07690; match to protein family HMM TIGR00885; L-fucose transporter 3114312..3115628 Escherichia coli E24377A 5586386 YP_001464125.1 CDS fucI NC_009801.1 3115661 3117436 D catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3115661..3117436 Escherichia coli E24377A 5586819 YP_001464126.1 CDS fucK NC_009801.1 3117545 3118963 D identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR02628; L-fuculokinase 3117545..3118963 Escherichia coli E24377A 5588857 YP_001464127.1 CDS fucU NC_009801.1 3118965 3119387 D identified by similarity to SP:P0AEN8; match to protein family HMM PF05025; fucose operon protein FucU 3118965..3119387 Escherichia coli E24377A 5586695 YP_001464128.1 CDS fucR NC_009801.1 3119445 3120176 D regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 3119445..3120176 Escherichia coli E24377A 5586587 YP_001464129.1 CDS EcE24377A_3110 NC_009801.1 3119568 3119681 R identified by glimmer; hypothetical protein complement(3119568..3119681) Escherichia coli E24377A 5589736 YP_001464130.1 CDS EcE24377A_3112 NC_009801.1 3120220 3121320 R RNA 2'-O-ribose methyltransferase complement(3120220..3121320) Escherichia coli E24377A 5588645 YP_001464131.1 CDS EcE24377A_3113 NC_009801.1 3121313 3121708 R identified by match to protein family HMM PF04241; hypothetical protein complement(3121313..3121708) Escherichia coli E24377A 5589380 YP_001464132.1 CDS gcvA NC_009801.1 3121727 3122644 R Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA complement(3121727..3122644) Escherichia coli E24377A 5587898 YP_001464133.1 CDS EcE24377A_3115 NC_009801.1 3122995 3123222 R identified by match to protein family HMM PF06004; lipoprotein complement(3122995..3123222) Escherichia coli E24377A 5588287 YP_001464134.1 CDS csdA NC_009801.1 3123414 3124619 D identified by match to protein family HMM PF00266; match to protein family HMM TIGR03392; cysteine sulfinate desulfinase 3123414..3124619 Escherichia coli E24377A 5587381 YP_001464135.1 CDS csdE NC_009801.1 3124619 3125062 D identified by similarity to SP:P0AGF2; match to protein family HMM PF02657; match to protein family HMM TIGR03391; cysteine desulfuration protein CsdE 3124619..3125062 Escherichia coli E24377A 5588662 YP_001464136.1 CDS EcE24377A_3118 NC_009801.1 3125113 3125919 R identified by match to protein family HMM PF00899; ThiF family protein complement(3125113..3125919) Escherichia coli E24377A 5588246 YP_001464137.1 CDS mltA NC_009801.1 3125996 3127093 R membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A complement(3125996..3127093) Escherichia coli E24377A 5586467 YP_001464138.1 CDS EcE24377A_3123 NC_009801.1 3128230 3128730 D identified by similarity to GB:AAN81830.1; match to protein family HMM PF05591; match to protein family HMM TIGR03358; hypothetical protein 3128230..3128730 Escherichia coli E24377A 5589566 YP_001464139.1 CDS EcE24377A_3124 NC_009801.1 3128789 3130327 D identified by match to protein family HMM PF05943; match to protein family HMM TIGR03355; hypothetical protein 3128789..3130327 Escherichia coli E24377A 5587803 YP_001464140.1 CDS EcE24377A_3125 NC_009801.1 3130345 3131682 D identified by similarity to GB:AAN81832.1; match to protein family HMM PF05936; match to protein family HMM TIGR03353; hypothetical protein 3130345..3131682 Escherichia coli E24377A 5589163 YP_001464141.1 CDS EcE24377A_3126 NC_009801.1 3131679 3132344 D identified by match to protein family HMM TIGR03349; DotU family type IV/VI secretion system protein 3131679..3132344 Escherichia coli E24377A 5587744 YP_001464142.1 CDS EcE24377A_3127 NC_009801.1 3132357 3134009 D identified by match to protein family HMM PF00691; OmpA domain-containing protein 3132357..3134009 Escherichia coli E24377A 5589683 YP_001464143.1 CDS EcE24377A_3128 NC_009801.1 3134067 3134558 D identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344; hypothetical protein 3134067..3134558 Escherichia coli E24377A 5586414 YP_001464144.1 CDS EcE24377A_3129 NC_009801.1 3134749 3137394 D identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03345; ClpA/ClpB family protein 3134749..3137394 Escherichia coli E24377A 5587448 YP_001464145.1 CDS EcE24377A_3130 NC_009801.1 3137406 3139913 D identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361; ImpA family type VI secretion-associated protein 3137406..3139913 Escherichia coli E24377A 5589797 YP_001464146.1 CDS EcE24377A_3131 NC_009801.1 3139935 3140537 D hypothetical protein 3139935..3140537 Escherichia coli E24377A 5586998 YP_001464147.1 CDS EcE24377A_3132 NC_009801.1 3140539 3141090 D hypothetical protein 3140539..3141090 Escherichia coli E24377A 5587394 YP_001464148.1 CDS EcE24377A_3133 NC_009801.1 3141298 3141681 D identified by match to protein family HMM TIGR03352; type VI secretion lipoprotein 3141298..3141681 Escherichia coli E24377A 5588905 YP_001464149.1 CDS EcE24377A_3134 NC_009801.1 3141685 3142113 D identified by similarity to GB:AAN81847.1; match to protein family HMM PF04965; match to protein family HMM TIGR03357; hypothetical protein 3141685..3142113 Escherichia coli E24377A 5586724 YP_001464150.1 CDS EcE24377A_3135 NC_009801.1 3142113 3143489 D identified by match to protein family HMM PF06812; ImpA-related N-terminal domain-containing protein 3142113..3143489 Escherichia coli E24377A 5586337 YP_001464151.1 CDS EcE24377A_3136 NC_009801.1 3143554 3144102 D identified by glimmer; hypothetical protein 3143554..3144102 Escherichia coli E24377A 5586980 YP_001464152.1 CDS amiC NC_009801.1 3144448 3145701 R identified by similarity to SP:P63883; match to protein family HMM PF01520; match to protein family HMM TIGR01409; N-acetylmuramoyl-L-alanine amidase complement(3144448..3145701) Escherichia coli E24377A 5588135 YP_001464153.1 CDS argA NC_009801.1 3145933 3147264 D catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3145933..3147264 Escherichia coli E24377A 5590064 YP_001464154.1 CDS recD NC_009801.1 3147326 3149152 R helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha complement(3147326..3149152) Escherichia coli E24377A 5589534 YP_001464155.1 CDS recB NC_009801.1 3149152 3152694 R helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta complement(3149152..3152694) Escherichia coli E24377A 5590490 YP_001464156.1 CDS ptrA NC_009801.1 3152687 3155575 R identified by similarity to SP:P05458; match to protein family HMM PF00675; match to protein family HMM PF05193; protease III complement(3152687..3155575) Escherichia coli E24377A 5588723 YP_001464157.1 CDS recC NC_009801.1 3155751 3159119 R catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma complement(3155751..3159119) Escherichia coli E24377A 5587054 YP_001464158.1 CDS ppdC NC_009801.1 3159132 3159455 R identified by similarity to SP:P08372; match to protein family HMM PF07963; match to protein family HMM TIGR02532; hypothetical protein complement(3159132..3159455) Escherichia coli E24377A 5588621 YP_001464159.1 CDS EcE24377A_3144 NC_009801.1 3159440 3159847 R identified by similarity to SP:P08370; hypothetical protein complement(3159440..3159847) Escherichia coli E24377A 5588726 YP_001464160.1 CDS ppdB NC_009801.1 3159844 3160407 R identified by similarity to SP:P08371; match to protein family HMM PF07963; match to protein family HMM TIGR02532; hypothetical protein complement(3159844..3160407) Escherichia coli E24377A 5590794 YP_001464161.1 CDS ppdA NC_009801.1 3160398 3160868 R identified by similarity to SP:P33554; match to protein family HMM PF07963; match to protein family HMM TIGR02532; hypothetical protein complement(3160398..3160868) Escherichia coli E24377A 5590287 YP_001464162.1 CDS thyA NC_009801.1 3161053 3161847 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(3161053..3161847) Escherichia coli E24377A 5586350 YP_001464163.1 CDS lgt NC_009801.1 3161854 3162729 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(3161854..3162729) Escherichia coli E24377A 5590133 YP_001464164.1 CDS ptsP NC_009801.1 3162880 3165126 R member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain complement(3162880..3165126) Escherichia coli E24377A 5586216 YP_001464165.1 CDS nudH NC_009801.1 3165139 3165669 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(3165139..3165669) Escherichia coli E24377A 5586298 YP_001464166.1 CDS mutH NC_009801.1 3166354 3167043 D MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3166354..3167043 Escherichia coli E24377A 5587996 YP_001464167.1 CDS EcE24377A_3152 NC_009801.1 3167112 3167825 D identified by match to protein family HMM PF03741; TerC family integral membrane protein 3167112..3167825 Escherichia coli E24377A 5588643 YP_001464168.1 CDS EcE24377A_3153 NC_009801.1 3167963 3168181 D identified by similarity to GB:AAV78717.1; match to protein family HMM PF06004; lipoprotein 3167963..3168181 Escherichia coli E24377A 5589249 YP_001464169.1 CDS tas NC_009801.1 3168289 3169329 D complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo-keto reductase 3168289..3169329 Escherichia coli E24377A 5589254 YP_001464170.1 CDS lplT NC_009801.1 3169361 3170524 R identified by match to protein family HMM PF07690; lysophospholipid transporter LplT complement(3169361..3170524) Escherichia coli E24377A 5589518 YP_001464171.1 CDS aas NC_009801.1 3170547 3172706 R Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase complement(3170547..3172706) Escherichia coli E24377A 5590030 YP_001464172.1 CDS galR NC_009801.1 3173292 3174323 D controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3173292..3174323 Escherichia coli E24377A 5589576 YP_001464173.1 CDS lysA NC_009801.1 3174330 3175592 R catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase complement(3174330..3175592) Escherichia coli E24377A 5588244 YP_001464174.1 CDS lysR NC_009801.1 3175714 3176649 D activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 3175714..3176649 Escherichia coli E24377A 5586575 YP_001464175.1 CDS EcE24377A_3159 NC_009801.1 3176355 3176453 R identified by glimmer; hypothetical protein complement(3176355..3176453) Escherichia coli E24377A 5586124 YP_001464176.1 CDS EcE24377A_3160 NC_009801.1 3176636 3177328 R identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035; racemase complement(3176636..3177328) Escherichia coli E24377A 5587021 YP_001464177.1 CDS araE NC_009801.1 3177457 3178875 R identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879; arabinose-proton symporter complement(3177457..3178875) Escherichia coli E24377A 5588916 YP_001464178.1 CDS EcE24377A_3163 NC_009801.1 3178826 3178924 R identified by glimmer; hypothetical protein complement(3178826..3178924) Escherichia coli E24377A 5588424 YP_001464179.1 CDS kduD NC_009801.1 3179190 3179951 R catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase complement(3179190..3179951) Escherichia coli E24377A 5586440 YP_001464180.1 CDS EcE24377A_3165 NC_009801.1 3179981 3180817 R 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase complement(3179981..3180817) Escherichia coli E24377A 5588391 YP_001464181.1 CDS EcE24377A_3166 NC_009801.1 3181104 3182285 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(3181104..3182285) Escherichia coli E24377A 5586712 YP_001464182.1 CDS EcE24377A_3167 NC_009801.1 3182540 3183769 D identified by match to protein family HMM PF01490; match to protein family HMM TIGR00814; serine transporter family protein 3182540..3183769 Escherichia coli E24377A 5587920 YP_001464183.1 CDS EcE24377A_3168 NC_009801.1 3184169 3184861 D identified by similarity to GB:AAZ89600.1; hypothetical protein 3184169..3184861 Escherichia coli E24377A 5589596 YP_001464184.1 CDS EcE24377A_3169 NC_009801.1 3185195 3186004 D identified by match to protein family HMM PF00486; transcriptional regulatory protein, C terminal 3185195..3186004 Escherichia coli E24377A 5588855 YP_001464185.1 CDS EcE24377A_3170 NC_009801.1 3186087 3186479 D hypothetical protein 3186087..3186479 Escherichia coli E24377A 5587931 YP_001464186.1 CDS EcE24377A_3171 NC_009801.1 3186512 3186652 R identified by glimmer; hypothetical protein complement(3186512..3186652) Escherichia coli E24377A 5588773 YP_001464187.1 CDS EcE24377A_3172 NC_009801.1 3187962 3188453 D identified by match to protein family HMM PF07720; hypothetical protein 3187962..3188453 Escherichia coli E24377A 5588192 YP_001464188.1 CDS EcE24377A_3173 NC_009801.1 3188788 3190164 D identified by match to protein family HMM PF00486; match to protein family HMM PF07719; transcriptional regulator 3188788..3190164 Escherichia coli E24377A 5589372 YP_001464189.1 CDS EcE24377A_3174 NC_009801.1 3190617 3190835 R identified by glimmer; hypothetical protein complement(3190617..3190835) Escherichia coli E24377A 5587119 YP_001464190.1 CDS EcE24377A_3175 NC_009801.1 3191153 3191599 R identified by match to protein family HMM PF00196; LuxR family transcriptional regulator complement(3191153..3191599) Escherichia coli E24377A 5588728 YP_001464191.1 CDS EcE24377A_3176 NC_009801.1 3192006 3192437 R identified by similarity to GB:AAA83039.1; hypothetical protein complement(3192006..3192437) Escherichia coli E24377A 5587188 YP_001464192.1 CDS eprK NC_009801.1 3193251 3193985 R identified by match to protein family HMM PF01514; match to protein family HMM TIGR02544; type III secretion apparatus lipoprotein EprK complement(3193251..3193985) Escherichia coli E24377A 5586820 YP_001464193.1 CDS eprH NC_009801.1 3194586 3195767 R identified by match to protein family HMM TIGR02554; type III secretion apparatus protein EprH complement(3194586..3195767) Escherichia coli E24377A 5586919 YP_001464194.1 CDS EcE24377A_3181 NC_009801.1 3197269 3198000 R identified by similarity to SP:P40727; match to protein family HMM PF01312; FlhB/HrpN/YscU/SpaS family protein complement(3197269..3198000) Escherichia coli E24377A 5588784 YP_001464195.1 CDS epaR NC_009801.1 3198009 3198776 R identified by similarity to GB:BAB60840.1; match to protein family HMM PF01311; match to protein family HMM TIGR01401; type III secretion apparatus protein EpaR complement(3198009..3198776) Escherichia coli E24377A 5586533 YP_001464196.1 CDS epaQ NC_009801.1 3198778 3199038 R identified by similarity to GB:AAZ31292.1; match to protein family HMM PF01313; match to protein family HMM TIGR01403; type III secretion apparatus protein EpaQ complement(3198778..3199038) Escherichia coli E24377A 5587638 YP_001464197.1 CDS spaP NC_009801.1 3199048 3199713 R part of a type III secretory system probably involved in invasion into eukaryotic cells; surface presentation of antigens protein SpaP complement(3199048..3199713) Escherichia coli E24377A 5586522 YP_001464198.1 CDS epaO2 NC_009801.1 3199703 3200275 R identified by match to protein family HMM PF01052; match to protein family HMM TIGR02551; type III secretion apparatus protein EpaO2 complement(3199703..3200275) Escherichia coli E24377A 5589728 YP_001464199.1 CDS EcE24377A_3186 NC_009801.1 3200650 3200748 R identified by similarity to GB:BAB37150.1; type III secretion apparatus protein, truncation complement(3200650..3200748) Escherichia coli E24377A 5589492 YP_001464200.1 CDS EcE24377A_3187 NC_009801.1 3200782 3202434 R hypothetical protein complement(3200782..3202434) Escherichia coli E24377A 5587286 YP_001464201.1 CDS EcE24377A_3188 NC_009801.1 3202458 3202568 D identified by glimmer; hypothetical protein 3202458..3202568 Escherichia coli E24377A 5586455 YP_001464202.1 CDS EcE24377A_3190 NC_009801.1 3202778 3203533 R identified by match to protein family HMM PF01476; match to protein family HMM PF01551; M23B family peptidase complement(3202778..3203533) Escherichia coli E24377A 5590147 YP_001464203.1 CDS xdhA NC_009801.1 3203948 3206245 D molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3203948..3206245 Escherichia coli E24377A 5586614 YP_001464204.1 CDS xdhB NC_009801.1 3206256 3207134 D FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3206256..3207134 Escherichia coli E24377A 5587358 YP_001464205.1 CDS xdhC NC_009801.1 3207131 3207610 D iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3207131..3207610 Escherichia coli E24377A 5587797 YP_001464206.1 CDS EcE24377A_3194 NC_009801.1 3207650 3209428 R identified by match to protein family HMM PF00158; match to protein family HMM PF02954; sigma-54 dependent trancsriptional regulator complement(3207650..3209428) Escherichia coli E24377A 5587617 YP_001464207.1 CDS EcE24377A_3195 NC_009801.1 3209904 3211094 D ygeW; identified by match to protein family HMM PF00185; match to protein family HMM PF02729; aspartate/ornithine carbamoyltransferase 3209904..3211094 Escherichia coli E24377A 5590502 YP_001464208.1 CDS EcE24377A_3196 NC_009801.1 3211152 3212348 D catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3211152..3212348 Escherichia coli E24377A 5590157 YP_001464209.1 CDS EcE24377A_3197 NC_009801.1 3212406 3213617 D Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3212406..3213617 Escherichia coli E24377A 5589722 YP_001464210.1 CDS hyuA NC_009801.1 3213670 3215055 D catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3213670..3215055 Escherichia coli E24377A 5587404 YP_001464211.1 CDS EcE24377A_3199 NC_009801.1 3215103 3216035 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3215103..3216035 Escherichia coli E24377A 5589941 YP_001464212.1 CDS EcE24377A_3200 NC_009801.1 3216076 3217701 R identified by match to protein family HMM PF00364; match to protein family HMM PF02625; match to protein family HMM TIGR03309; xanthine dehydrogenase accessory factor complement(3216076..3217701) Escherichia coli E24377A 5587965 YP_001464213.1 CDS EcE24377A_3201 NC_009801.1 3217749 3218456 R identified by similarity to SP:Q46809; match to protein family HMM TIGR03172; hypothetical protein complement(3217749..3218456) Escherichia coli E24377A 5588854 YP_001464214.1 CDS EcE24377A_3203 NC_009801.1 3218622 3219200 D identified by similarity to SP:Q46810; match to protein family HMM TIGR03310; hypothetical protein 3218622..3219200 Escherichia coli E24377A 5588965 YP_001464215.1 CDS EcE24377A_3202 NC_009801.1 3218843 3219073 R identified by glimmer; hypothetical protein complement(3218843..3219073) Escherichia coli E24377A 5586397 YP_001464216.1 CDS EcE24377A_3204 NC_009801.1 3219522 3222620 D with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; selenate reductase subunit YgfK 3219522..3222620 Escherichia coli E24377A 5587624 YP_001464217.1 CDS ssnA NC_009801.1 3222623 3223951 D in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; chlorohydrolase/aminohydrolase 3222623..3223951 Escherichia coli E24377A 5587388 YP_001464218.1 CDS EcE24377A_3206 NC_009801.1 3224002 3224781 D with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; selenate reductase subunit YgfM 3224002..3224781 Escherichia coli E24377A 5586200 YP_001464219.1 CDS EcE24377A_3207 NC_009801.1 3224778 3227648 D with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; selenate reductase subunit YgfN 3224778..3227648 Escherichia coli E24377A 5590773 YP_001464220.1 CDS EcE24377A_3208 NC_009801.1 3227813 3229213 D identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine/uracil permease 3227813..3229213 Escherichia coli E24377A 5589302 YP_001464221.1 CDS guaD NC_009801.1 3229231 3230547 D Catalyzes the deamination of guanine; guanine deaminase 3229231..3230547 Escherichia coli E24377A 5590714 YP_001464222.1 CDS EcE24377A_3210 NC_009801.1 3230583 3231950 D identified by match to protein family HMM PF00860; match to protein family HMM PF00916; sulfate permease inorganic anion transporter 3230583..3231950 Escherichia coli E24377A 5588860 YP_001464223.1 CDS EcE24377A_3211 NC_009801.1 3231986 3232474 R identified by match to protein family HMM PF00037; (4Fe-4S)-binding protein complement(3231986..3232474) Escherichia coli E24377A 5590798 YP_001464224.1 CDS EcE24377A_3212 NC_009801.1 3232474 3234393 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(3232474..3234393) Escherichia coli E24377A 5590376 YP_001464225.1 CDS EcE24377A_3213 NC_009801.1 3234829 3236277 D identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine permease 3234829..3236277 Escherichia coli E24377A 5588181 YP_001464226.1 CDS EcE24377A_3214 NC_009801.1 3236261 3236404 D identified by glimmer; hypothetical protein 3236261..3236404 Escherichia coli E24377A 5589572 YP_001464227.1 CDS idi NC_009801.1 3236527 3237075 D catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3236527..3237075 Escherichia coli E24377A 5587222 YP_001464228.1 CDS lysS NC_009801.1 3237118 3238635 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(3237118..3238635) Escherichia coli E24377A 5588512 YP_001464229.1 CDS recJ NC_009801.1 3239834 3241567 R 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ complement(3239834..3241567) Escherichia coli E24377A 5588399 YP_001464230.1 CDS dsbC NC_009801.1 3241573 3242283 R DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC complement(3241573..3242283) Escherichia coli E24377A 5586840 YP_001464231.1 CDS xerD NC_009801.1 3242308 3243204 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(3242308..3243204) Escherichia coli E24377A 5588602 YP_001464232.1 CDS fldB NC_009801.1 3243316 3243837 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3243316..3243837 Escherichia coli E24377A 5590170 YP_001464233.1 CDS EcE24377A_3222 NC_009801.1 3243877 3244284 R identified by match to protein family HMM PF07254; hypothetical protein complement(3243877..3244284) Escherichia coli E24377A 5586217 YP_001464234.1 CDS EcE24377A_3223 NC_009801.1 3244265 3244531 R identified by match to protein family HMM PF03937; hypothetical protein complement(3244265..3244531) Escherichia coli E24377A 5588593 YP_001464235.1 CDS EcE24377A_3224 NC_009801.1 3244506 3244697 D identified by similarity to GB:AAN81926.1; hypothetical protein 3244506..3244697 Escherichia coli E24377A 5590191 YP_001464236.1 CDS ygfZ NC_009801.1 3244774 3245754 D physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 3244774..3245754 Escherichia coli E24377A 5588800 YP_001464237.1 CDS EcE24377A_3226 NC_009801.1 3245831 3246490 R identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065; hemolysin III family channel protein complement(3245831..3246490) Escherichia coli E24377A 5589494 YP_001464238.1 CDS EcE24377A_3227 NC_009801.1 3246654 3246965 R identified by match to protein family HMM PF06164; hypothetical protein complement(3246654..3246965) Escherichia coli E24377A 5590140 YP_001464239.1 CDS bglA NC_009801.1 3247004 3248443 D identified by similarity to SP:Q46829; match to protein family HMM PF00232; 6-phospho-beta-glucosidase 3247004..3248443 Escherichia coli E24377A 5588940 YP_001464240.1 CDS EcE24377A_3229 NC_009801.1 3248500 3249243 R identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659; hypothetical protein complement(3248500..3249243) Escherichia coli E24377A 5586860 YP_001464241.1 CDS gcvP NC_009801.1 3249509 3252382 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(3249509..3252382) Escherichia coli E24377A 5590750 YP_001464242.1 CDS gcvH NC_009801.1 3252501 3252890 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(3252501..3252890) Escherichia coli E24377A 5586886 YP_001464243.1 CDS gcvT NC_009801.1 3252914 3254008 R catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T complement(3252914..3254008) Escherichia coli E24377A 5586188 YP_001464244.1 CDS EcE24377A_3233 NC_009801.1 3254268 3254381 D identified by glimmer; hypothetical protein 3254268..3254381 Escherichia coli E24377A 5590559 YP_001464245.1 CDS EcE24377A_3234 NC_009801.1 3254455 3255657 R identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988; hypothetical protein complement(3254455..3255657) Escherichia coli E24377A 5586987 YP_001464246.1 CDS ubiH NC_009801.1 3255680 3256858 R Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase complement(3255680..3256858) Escherichia coli E24377A 5587500 YP_001464247.1 CDS pepP NC_009801.1 3256855 3258180 R exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II complement(3256855..3258180) Escherichia coli E24377A 5587672 YP_001464248.1 CDS EcE24377A_3237 NC_009801.1 3258206 3258784 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(3258206..3258784) Escherichia coli E24377A 5590126 YP_001464249.1 CDS EcE24377A_3238 NC_009801.1 3258952 3259281 D identified by match to protein family HMM PF05164; Z-ring-associated protein 3258952..3259281 Escherichia coli E24377A 5586133 YP_001464250.2 CDS EcE24377A_3239 NC_009801.1 3259581 3260129 D ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; ligase 3259581..3260129 Escherichia coli E24377A 5586344 YP_001464251.1 CDS serA NC_009801.1 3260910 3262142 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(3260910..3262142) Escherichia coli E24377A 5589463 YP_001464252.1 CDS rpiA NC_009801.1 3262398 3263057 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(3262398..3263057) Escherichia coli E24377A 5590568 YP_001464253.1 CDS iciA NC_009801.1 3263440 3264333 D specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3263440..3264333 Escherichia coli E24377A 5589205 YP_001464254.1 CDS msm NC_009801.1 3264537 3266681 D MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 3264537..3266681 Escherichia coli E24377A 5587345 YP_001464255.1 CDS EcE24377A_3245 NC_009801.1 3266674 3267669 D functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 3266674..3267669 Escherichia coli E24377A 5586664 YP_001464256.1 CDS EcE24377A_3246 NC_009801.1 3267680 3268465 D catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA; methylmalonyl-CoA decarboxylase 3267680..3268465 Escherichia coli E24377A 5589211 YP_001464257.1 CDS EcE24377A_3247 NC_009801.1 3269965 3270861 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(3269965..3270861) Escherichia coli E24377A 5590666 YP_001464258.1 CDS EcE24377A_3249 NC_009801.1 3271028 3271768 R identified by similarity to SP:P0ADS8; match to protein family HMM PF04402; hypothetical protein complement(3271028..3271768) Escherichia coli E24377A 5587424 YP_001464259.1 CDS argO NC_009801.1 3271861 3272496 R Involved in the export of arginine; arginine exporter protein complement(3271861..3272496) Escherichia coli E24377A 5589102 YP_001464260.1 CDS mscS NC_009801.1 3272635 3273495 R participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS complement(3272635..3273495) Escherichia coli E24377A 5590375 YP_001464261.1 CDS EcE24377A_3252 NC_009801.1 3273675 3273851 D identified by glimmer; hypothetical protein 3273675..3273851 Escherichia coli E24377A 5586018 YP_001464262.1 CDS fbaA NC_009801.1 3273853 3274932 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(3273853..3274932) Escherichia coli E24377A 5588170 YP_001464263.1 CDS pgk NC_009801.1 3275147 3276310 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(3275147..3276310) Escherichia coli E24377A 5585986 YP_001464264.1 CDS epd NC_009801.1 3276360 3277379 R NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase complement(3276360..3277379) Escherichia coli E24377A 5588405 YP_001464265.1 CDS EcE24377A_3256 NC_009801.1 3277333 3277434 R identified by glimmer; hypothetical protein complement(3277333..3277434) Escherichia coli E24377A 5586722 YP_001464266.1 CDS EcE24377A_3257 NC_009801.1 3277580 3277672 R identified by glimmer; hypothetical protein complement(3277580..3277672) Escherichia coli E24377A 5586847 YP_001464267.1 CDS EcE24377A_3258 NC_009801.1 3277751 3278182 D identified by match to protein family HMM PF03479; hypothetical protein 3277751..3278182 Escherichia coli E24377A 5590557 YP_001464268.1 CDS EcE24377A_3259 NC_009801.1 3278205 3278783 D hypothetical protein 3278205..3278783 Escherichia coli E24377A 5589980 YP_001464269.1 CDS EcE24377A_3260 NC_009801.1 3278784 3279491 D hypothetical protein 3278784..3279491 Escherichia coli E24377A 5588496 YP_001464270.1 CDS EcE24377A_3261 NC_009801.1 3279479 3280156 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3279479..3280156 Escherichia coli E24377A 5586779 YP_001464271.1 CDS EcE24377A_3263 NC_009801.1 3280117 3280827 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3280117..3280827 Escherichia coli E24377A 5590449 YP_001464272.1 CDS frcK NC_009801.1 3280799 3281512 R identified by similarity to GB:AAZ89673.1; fructose transport system kinase complement(3280799..3281512) Escherichia coli E24377A 5587406 YP_001464273.1 CDS EcE24377A_3264 NC_009801.1 3281509 3282018 R identified by match to protein family HMM PF05068; DNA-binding transcriptional regulator complement(3281509..3282018) Escherichia coli E24377A 5587194 YP_001464274.1 CDS glpX1 NC_009801.1 3282040 3283005 R identified by match to protein family HMM PF03320; match to protein family HMM TIGR00330; fructose-1,6-bisphosphatase II-like protein complement(3282040..3283005) Escherichia coli E24377A 5589417 YP_001464275.1 CDS sorE NC_009801.1 3283002 3284279 R identified by similarity to SP:P37084; match to protein family HMM PF00107; match to protein family HMM PF08240; L-sorbose 1-phosphate reductase complement(3283002..3284279) Escherichia coli E24377A 5589213 YP_001464276.1 CDS cmtA NC_009801.1 3284294 3285682 R identified by similarity to SP:P69826; match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851; PTS system mannitol-specific transporter subunit cryptic EIICB complement(3284294..3285682) Escherichia coli E24377A 5587610 YP_001464277.1 CDS cmtB NC_009801.1 3285710 3286153 R TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA complement(3285710..3286153) Escherichia coli E24377A 5588614 YP_001464278.1 CDS tkt NC_009801.1 3286467 3288458 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(3286467..3288458) Escherichia coli E24377A 5587764 YP_001464279.1 CDS EcE24377A_3270 NC_009801.1 3288736 3289494 D identified by match to protein family HMM PF01435; M48B family peptidase 3288736..3289494 Escherichia coli E24377A 5588248 YP_001464280.1 CDS EcE24377A_3271 NC_009801.1 3289550 3290293 R identified by similarity to GB:AAV79415.1; match to protein family HMM PF07071; hypothetical protein complement(3289550..3290293) Escherichia coli E24377A 5589724 YP_001464281.1 CDS EcE24377A_3272 NC_009801.1 3290280 3291389 R identified by match to protein family HMM PF01212; match to protein family HMM PF03841; match to protein family HMM TIGR01437; pyridoxal phosphate-dependent enzyme complement(3290280..3291389) Escherichia coli E24377A 5588500 YP_001464282.1 CDS EcE24377A_3273 NC_009801.1 3291079 3291189 D identified by glimmer; hypothetical protein 3291079..3291189 Escherichia coli E24377A 5587834 YP_001464283.1 CDS EcE24377A_3274 NC_009801.1 3291393 3292250 R identified by match to protein family HMM PF03613; PTS system mannose/fructose/sorbose family transporter subunit IID complement(3291393..3292250) Escherichia coli E24377A 5586481 YP_001464284.1 CDS EcE24377A_3275 NC_009801.1 3292250 3292999 R identified by match to protein family HMM PF03609; PTS system sorbose-specific IIC component complement(3292250..3292999) Escherichia coli E24377A 5588557 YP_001464285.1 CDS EcE24377A_3276 NC_009801.1 3293025 3293510 R identified by match to protein family HMM PF03830; PTS system sorbose subfamily transporter subunit IIB complement(3293025..3293510) Escherichia coli E24377A 5590196 YP_001464286.1 CDS EcE24377A_3277 NC_009801.1 3293521 3293949 R identified by match to protein family HMM PF03610; PTS system fructose IIA component complement(3293521..3293949) Escherichia coli E24377A 5587173 YP_001464287.1 CDS EcE24377A_3278 NC_009801.1 3294068 3296866 R identified by match to protein family HMM PF00158; match to protein family HMM PF00874; sigma-54 dependent transcription regulator complement(3294068..3296866) Escherichia coli E24377A 5589483 YP_001464288.1 CDS speB NC_009801.1 3297125 3298045 R catalyzes the formation of putrescine from agmatine; agmatinase complement(3297125..3298045) Escherichia coli E24377A 5589638 YP_001464289.1 CDS EcE24377A_3280 NC_009801.1 3298181 3298912 R lipoprotein complement(3298181..3298912) Escherichia coli E24377A 5587154 YP_001464290.1 CDS speA NC_009801.1 3299058 3301034 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(3299058..3301034) Escherichia coli E24377A 5590224 YP_001464291.1 CDS EcE24377A_3282 NC_009801.1 3301043 3301189 R identified by similarity to SP:P64567; hypothetical protein complement(3301043..3301189) Escherichia coli E24377A 5587999 YP_001464292.1 CDS EcE24377A_3283 NC_009801.1 3301509 3301634 D identified by glimmer; hypothetical protein 3301509..3301634 Escherichia coli E24377A 5590192 YP_001464293.1 CDS metK NC_009801.1 3301829 3302983 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3301829..3302983 Escherichia coli E24377A 5590816 YP_001464294.1 CDS EcE24377A_3285 NC_009801.1 3303046 3303180 D identified by glimmer; hypothetical protein 3303046..3303180 Escherichia coli E24377A 5587365 YP_001464295.1 CDS galP NC_009801.1 3303419 3304813 D identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879; galactose-proton symporter 3303419..3304813 Escherichia coli E24377A 5590860 YP_001464296.1 CDS EcE24377A_3287 NC_009801.1 3304890 3305387 D identified by match to protein family HMM PF03926; hypothetical protein 3304890..3305387 Escherichia coli E24377A 5586960 YP_001464297.1 CDS endA NC_009801.1 3305482 3306189 D identified by similarity to SP:P25736; match to protein family HMM PF04231; endonuclease I 3305482..3306189 Escherichia coli E24377A 5586818 YP_001464298.1 CDS EcE24377A_3289 NC_009801.1 3306269 3307000 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3306269..3307000 Escherichia coli E24377A 5589964 YP_001464299.1 CDS gshB NC_009801.1 3307013 3307963 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3307013..3307963 Escherichia coli E24377A 5588126 YP_001464300.1 CDS EcE24377A_3291 NC_009801.1 3308072 3308635 D identified by similarity to SP:P0A8W7; match to protein family HMM PF02622; hypothetical protein 3308072..3308635 Escherichia coli E24377A 5587141 YP_001464301.1 CDS EcE24377A_3292 NC_009801.1 3308635 3309051 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3308635..3309051 Escherichia coli E24377A 5589594 YP_001464302.1 CDS EcE24377A_3293 NC_009801.1 3309105 3309209 D identified by glimmer; hypothetical protein 3309105..3309209 Escherichia coli E24377A 5589521 YP_001464303.1 CDS EcE24377A_3294 NC_009801.1 3309244 3310224 R identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420; twitching motility family protein complement(3309244..3310224) Escherichia coli E24377A 5588527 YP_001464304.1 CDS EcE24377A_3295 NC_009801.1 3310242 3310946 D identified by match to protein family HMM PF01168; match to protein family HMM TIGR00044; alanine racemase 3310242..3310946 Escherichia coli E24377A 5587081 YP_001464305.1 CDS EcE24377A_3296 NC_009801.1 3310964 3311530 D identified by match to protein family HMM PF02325; hypothetical protein 3310964..3311530 Escherichia coli E24377A 5589323 YP_001464306.1 CDS EcE24377A_3297 NC_009801.1 3311515 3311817 D identified by similarity to GB:AAP18250.1; match to protein family HMM PF02594; match to protein family HMM TIGR00251; hypothetical protein 3311515..3311817 Escherichia coli E24377A 5590688 YP_001464307.1 CDS rdgB NC_009801.1 3311825 3312418 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3311825..3312418 Escherichia coli E24377A 5590044 YP_001464308.1 CDS EcE24377A_3299 NC_009801.1 3312411 3313547 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3312411..3313547 Escherichia coli E24377A 5590244 YP_001464309.1 CDS EcE24377A_3300 NC_009801.1 3313702 3314709 R identified by match to protein family HMM PF06717; hypothetical protein complement(3313702..3314709) Escherichia coli E24377A 5588707 YP_001464310.1 CDS ansB NC_009801.1 3314826 3315872 R catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II complement(3314826..3315872) Escherichia coli E24377A 5589022 YP_001464311.1 CDS EcE24377A_3302 NC_009801.1 3316048 3316764 R identified by similarity to SP:P0ADS9; hypothetical protein complement(3316048..3316764) Escherichia coli E24377A 5590300 YP_001464312.1 CDS EcE24377A_3303 NC_009801.1 3316788 3316928 R identified by glimmer; hypothetical protein complement(3316788..3316928) Escherichia coli E24377A 5587251 YP_001464313.1 CDS EcE24377A_3304 NC_009801.1 3316951 3317277 R identified by match to protein family HMM PF04320; hypothetical protein complement(3316951..3317277) Escherichia coli E24377A 5590246 YP_001464314.1 CDS trmB NC_009801.1 3317277 3317996 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(3317277..3317996) Escherichia coli E24377A 5587753 YP_001464315.1 CDS mutY NC_009801.1 3318127 3319209 D identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084; adenine DNA glycosylase 3318127..3319209 Escherichia coli E24377A 5590348 YP_001464316.1 CDS EcE24377A_3306 NC_009801.1 3319186 3319479 R identified by similarity to GB:AAN81997.1; hypothetical protein complement(3319186..3319479) Escherichia coli E24377A 5590268 YP_001464317.1 CDS EcE24377A_3308 NC_009801.1 3319237 3319512 D identified by match to protein family HMM PF04362; hypothetical protein 3319237..3319512 Escherichia coli E24377A 5588969 YP_001464318.1 CDS mltC NC_009801.1 3319577 3320656 D Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3319577..3320656 Escherichia coli E24377A 5586060 YP_001464319.1 CDS nupG NC_009801.1 3320858 3322114 D identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889; nucleoside permease NupG 3320858..3322114 Escherichia coli E24377A 5589872 YP_001464320.1 CDS speC NC_009801.1 3322164 3324299 R identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; ornithine decarboxylase complement(3322164..3324299) Escherichia coli E24377A 5586127 YP_001464321.1 CDS EcE24377A_3312 NC_009801.1 3324697 3325404 D identified by match to protein family HMM PF04474; hypothetical protein 3324697..3325404 Escherichia coli E24377A 5586103 YP_001464322.1 CDS EcE24377A_3314 NC_009801.1 3325783 3327045 D identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase 3325783..3327045 Escherichia coli E24377A 5586368 YP_001464323.1 CDS EcE24377A_3315 NC_009801.1 3327458 3327733 D identified by match to protein family HMM PF03811; IS1, transposase orfA 3327458..3327733 Escherichia coli E24377A 5589891 YP_001464324.1 CDS EcE24377A_3316 NC_009801.1 3327652 3328155 D identified by match to protein family HMM PF03400; IS1, transposase orfB 3327652..3328155 Escherichia coli E24377A 5588529 YP_001464325.1 CDS EcE24377A_3318 NC_009801.1 3329025 3329618 R identified by similarity to GB:AAS63192.1; hypothetical protein complement(3329025..3329618) Escherichia coli E24377A 5587115 YP_001464326.1 CDS EcE24377A_3319 NC_009801.1 3329739 3329846 R identified by glimmer; hypothetical protein complement(3329739..3329846) Escherichia coli E24377A 5587689 YP_001464327.1 CDS EcE24377A_3320 NC_009801.1 3330023 3332878 D identified by match to protein family HMM PF00176; match to protein family HMM PF00271; SNF2 family helicase 3330023..3332878 Escherichia coli E24377A 5588071 YP_001464328.1 CDS EcE24377A_3321 NC_009801.1 3332904 3333884 D identified by match to protein family HMM PF00004; ATPase AAA 3332904..3333884 Escherichia coli E24377A 5587875 YP_001464329.1 CDS EcE24377A_3322 NC_009801.1 3333894 3336281 D identified by match to protein family HMM PF00082; S8A family peptidase 3333894..3336281 Escherichia coli E24377A 5587091 YP_001464330.1 CDS EcE24377A_3323 NC_009801.1 3336291 3337919 D identified by match to protein family HMM PF01555; DNA methylase 3336291..3337919 Escherichia coli E24377A 5589709 YP_001464331.1 CDS EcE24377A_3325 NC_009801.1 3338000 3340792 D identified by match to protein family HMM PF04851; type III restriction enzyme, res subunit 3338000..3340792 Escherichia coli E24377A 5588190 YP_001464332.1 CDS EcE24377A_3324 NC_009801.1 3340022 3340447 R identified by glimmer; hypothetical protein complement(3340022..3340447) Escherichia coli E24377A 5588079 YP_001464333.1 CDS EcE24377A_3327 NC_009801.1 3341749 3343257 R identified by match to protein family HMM PF00078; match to protein family HMM PF08388; group II intron-encoded reverse transcriptase/maturase complement(3341749..3343257) Escherichia coli E24377A 5590522 YP_001464334.1 CDS EcE24377A_3329 NC_009801.1 3344319 3344621 R identified by match to protein family HMM PF01527; IS911, transposase orfA complement(3344319..3344621) Escherichia coli E24377A 5588136 YP_001464335.1 CDS EcE24377A_3330 NC_009801.1 3345110 3346396 R identified by similarity to GB:ABA74402.1; hypothetical protein complement(3345110..3346396) Escherichia coli E24377A 5586991 YP_001464336.1 CDS EcE24377A_3331 NC_009801.1 3346389 3348446 R identified by match to protein family HMM PF07728; ATPase complement(3346389..3348446) Escherichia coli E24377A 5588684 YP_001464337.1 CDS EcE24377A_3332 NC_009801.1 3349219 3349644 R identified by glimmer; hypothetical protein complement(3349219..3349644) Escherichia coli E24377A 5587593 YP_001464338.1 CDS EcE24377A_3333 NC_009801.1 3349641 3350024 R identified by similarity to GB:AAK00467.1; hypothetical protein complement(3349641..3350024) Escherichia coli E24377A 5587421 YP_001464339.1 CDS EcE24377A_3334 NC_009801.1 3351226 3351366 R identified by match to protein family HMM PF05321; hemolysin expression modulating protein complement(3351226..3351366) Escherichia coli E24377A 5586450 YP_001464340.1 CDS EcE24377A_3335 NC_009801.1 3352444 3353235 D identified by similarity to GB:AAN44467.1; hypothetical protein 3352444..3353235 Escherichia coli E24377A 5587553 YP_001464341.1 CDS EcE24377A_3337 NC_009801.1 3353914 3354522 D identified by similarity to GB:AAL08467.1; hypothetical protein 3353914..3354522 Escherichia coli E24377A 5586439 YP_001464342.1 CDS EcE24377A_3338 NC_009801.1 3356792 3357814 D identified by similarity to GB:AAZ76440.1; match to protein family HMM PF00665; match to protein family HMM PF02796; IS100, transposase 3356792..3357814 Escherichia coli E24377A 5586974 YP_001464343.1 CDS EcE24377A_3339 NC_009801.1 3358162 3358956 R identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein complement(3358162..3358956) Escherichia coli E24377A 5589513 YP_001464344.1 CDS EcE24377A_3341 NC_009801.1 3358956 3360128 R identified by similarity to SP:P15025; match to protein family HMM PF00665; IS21 family transposase complement(3358956..3360128) Escherichia coli E24377A 5590577 YP_001464345.1 CDS EcE24377A_3343 NC_009801.1 3361455 3362993 R identified by match to protein family HMM PF03050; IS66 family transposase complement(3361455..3362993) Escherichia coli E24377A 5589035 YP_001464346.1 CDS EcE24377A_3344 NC_009801.1 3363043 3363390 R identified by match to protein family HMM PF05717; IS66 family orf2 complement(3363043..3363390) Escherichia coli E24377A 5587590 YP_001464347.1 CDS EcE24377A_3345 NC_009801.1 3363387 3363776 R identified by match to protein family HMM PF01527; IS66 family orf1 complement(3363387..3363776) Escherichia coli E24377A 5589882 YP_001464348.1 CDS EcE24377A_3346 NC_009801.1 3364192 3365064 D identified by match to protein family HMM PF01926; GTPase 3364192..3365064 Escherichia coli E24377A 5589149 YP_001464349.1 CDS flu2 NC_009801.1 3365436 3368282 D identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; antigen 43 3365436..3368282 Escherichia coli E24377A 5589947 YP_001464350.1 CDS EcE24377A_3348 NC_009801.1 3368610 3369428 D identified by match to protein family HMM PF06067; hypothetical protein 3368610..3369428 Escherichia coli E24377A 5587063 YP_001464351.1 CDS EcE24377A_3349 NC_009801.1 3369520 3370002 D identified by match to protein family HMM PF03230; antirestriction protein 3369520..3370002 Escherichia coli E24377A 5590363 YP_001464352.1 CDS EcE24377A_3350 NC_009801.1 3370018 3370494 D identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608; RadC family DNA repair protein 3370018..3370494 Escherichia coli E24377A 5588333 YP_001464353.1 CDS EcE24377A_3351 NC_009801.1 3370581 3370802 D identified by similarity to GB:AAP18295.1; match to protein family HMM PF06174; hypothetical protein 3370581..3370802 Escherichia coli E24377A 5587250 YP_001464354.1 CDS EcE24377A_3352 NC_009801.1 3370882 3371250 D identified by similarity to GB:BAB36228.1; match to protein family HMM PF06154; hypothetical protein 3370882..3371250 Escherichia coli E24377A 5588772 YP_001464355.1 CDS EcE24377A_3353 NC_009801.1 3371340 3371717 D identified by match to protein family HMM PF06755; hypothetical protein 3371340..3371717 Escherichia coli E24377A 5586789 YP_001464356.1 CDS EcE24377A_3354 NC_009801.1 3371714 3372136 D identified by similarity to GB:AAN83011.1; match to protein family HMM PF06117; hypothetical protein 3371714..3372136 Escherichia coli E24377A 5586866 YP_001464357.1 CDS EcE24377A_3355 NC_009801.1 3372221 3373063 D identified by similarity to GB:CAE85207.1; hypothetical protein 3372221..3373063 Escherichia coli E24377A 5589241 YP_001464358.1 CDS EcE24377A_3356 NC_009801.1 3373401 3374459 R identified by match to protein family HMM PF00589; match to protein family HMM PF02899; phage integrase complement(3373401..3374459) Escherichia coli E24377A 5586549 YP_001464359.1 CDS EcE24377A_3357 NC_009801.1 3374501 3376156 R identified by match to protein family HMM PF07515; helicase/Zfx/Zfy transcription activation region domain-containing protein complement(3374501..3376156) Escherichia coli E24377A 5586099 YP_001464360.1 CDS EcE24377A_3358 NC_009801.1 3376149 3377678 R hypothetical protein complement(3376149..3377678) Escherichia coli E24377A 5589924 YP_001464361.1 CDS EcE24377A_3359 NC_009801.1 3377803 3381057 R identified by match to protein family HMM PF02369; Ig family protein complement(3377803..3381057) Escherichia coli E24377A 5589916 YP_001464362.1 CDS EcE24377A_3360 NC_009801.1 3381237 3381629 D identified by glimmer; hypothetical protein 3381237..3381629 Escherichia coli E24377A 5590694 YP_001464363.1 CDS EcE24377A_3361 NC_009801.1 3382305 3382964 R identified by glimmer; hypothetical protein complement(3382305..3382964) Escherichia coli E24377A 5587159 YP_001464364.1 CDS EcE24377A_3362 NC_009801.1 3383223 3385115 R identified by match to protein family HMM PF00580; UvrD family helicase complement(3383223..3385115) Escherichia coli E24377A 5587847 YP_001464365.1 CDS EcE24377A_3363 NC_009801.1 3385117 3386940 R identified by glimmer; hypothetical protein complement(3385117..3386940) Escherichia coli E24377A 5590167 YP_001464366.1 CDS EcE24377A_3365 NC_009801.1 3387412 3388104 R identified by similarity to GB:CAE13457.1; hypothetical protein complement(3387412..3388104) Escherichia coli E24377A 5590379 YP_001464367.1 CDS EcE24377A_3366 NC_009801.1 3388145 3388822 D identified by match to protein family HMM PF01527; IS66 family orf1 3388145..3388822 Escherichia coli E24377A 5590002 YP_001464368.1 CDS EcE24377A_3367 NC_009801.1 3388822 3389169 D identified by match to protein family HMM PF05717; IS66 family orf2 3388822..3389169 Escherichia coli E24377A 5587649 YP_001464369.1 CDS EcE24377A_3368 NC_009801.1 3389189 3390760 D identified by match to protein family HMM PF03050; IS66 family transposase 3389189..3390760 Escherichia coli E24377A 5589818 YP_001464370.1 CDS EcE24377A_3369 NC_009801.1 3390926 3391753 R identified by similarity to SP:P15026; match to protein family HMM PF01695; IS21 family transposition helper protein complement(3390926..3391753) Escherichia coli E24377A 5587865 YP_001464371.1 CDS EcE24377A_3370 NC_009801.1 3391753 3392925 R identified by match to protein family HMM PF00665; IS21 family transposase complement(3391753..3392925) Escherichia coli E24377A 5588534 YP_001464372.1 CDS EcE24377A_3371 NC_009801.1 3393100 3394467 R identified by similarity to SP:P0ACB0; match to protein family HMM PF00772; match to protein family HMM PF03796; match to protein family HMM TIGR00665; DnaB family helicase complement(3393100..3394467) Escherichia coli E24377A 5586433 YP_001464373.1 CDS EcE24377A_3372 NC_009801.1 3394664 3395029 D identified by glimmer; hypothetical protein 3394664..3395029 Escherichia coli E24377A 5587561 YP_001464374.1 CDS EcE24377A_3373 NC_009801.1 3395463 3396173 R identified by glimmer; hypothetical protein complement(3395463..3396173) Escherichia coli E24377A 5587787 YP_001464375.1 CDS EcE24377A_3374 NC_009801.1 3396170 3396430 R identified by glimmer; hypothetical protein complement(3396170..3396430) Escherichia coli E24377A 5588365 YP_001464376.1 CDS EcE24377A_3375 NC_009801.1 3396424 3397308 R chromosome partitioning protein complement(3396424..3397308) Escherichia coli E24377A 5587874 YP_001464377.1 CDS EcE24377A_3377 NC_009801.1 3397619 3398803 D identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase 3397619..3398803 Escherichia coli E24377A 5586022 YP_001464378.1 CDS rafR NC_009801.1 3398953 3399963 D identified by similarity to SP:P21867; match to protein family HMM PF00356; match to protein family HMM PF00532; HTH-type transcriptional regulator RafR 3398953..3399963 Escherichia coli E24377A 5590621 YP_001464379.1 CDS rafA NC_009801.1 3400059 3402185 D identified by similarity to SP:P16551; match to protein family HMM PF02065; alpha-galactosidase 3400059..3402185 Escherichia coli E24377A 5589615 YP_001464380.1 CDS lacY NC_009801.1 3402233 3403525 D lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 3402233..3403525 Escherichia coli E24377A 5588203 YP_001464381.1 CDS rafD NC_009801.1 3403525 3404955 D identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322; raffinose invertase 3403525..3404955 Escherichia coli E24377A 5588444 YP_001464382.1 CDS rafY NC_009801.1 3405150 3406544 D identified by similarity to GB:AAB71432.1; glycoporin RafY 3405150..3406544 Escherichia coli E24377A 5589945 YP_001464383.1 CDS EcE24377A_3384 NC_009801.1 3406621 3408159 R identified by match to protein family HMM PF03050; IS66 family transposase complement(3406621..3408159) Escherichia coli E24377A 5587246 YP_001464384.1 CDS EcE24377A_3385 NC_009801.1 3408209 3408556 R identified by match to protein family HMM PF05717; IS66 family orf2 complement(3408209..3408556) Escherichia coli E24377A 5586226 YP_001464385.1 CDS EcE24377A_3386 NC_009801.1 3408553 3408942 R identified by match to protein family HMM PF01527; IS66 family orf1 complement(3408553..3408942) Escherichia coli E24377A 5590393 YP_001464386.1 CDS EcE24377A_3387 NC_009801.1 3409199 3409633 R identified by similarity to SP:P0ACF8; match to protein family HMM PF00816; DNA-binding protein H-NS-like protein complement(3409199..3409633) Escherichia coli E24377A 5589313 YP_001464387.1 CDS EcE24377A_3389 NC_009801.1 3410890 3411438 R identified by glimmer; hypothetical protein complement(3410890..3411438) Escherichia coli E24377A 5589441 YP_001464388.1 CDS EcE24377A_3391 NC_009801.1 3413148 3413378 R identified by match to protein family HMM PF05930; prophage CP4-57 regulatory protein complement(3413148..3413378) Escherichia coli E24377A 5585954 YP_001464389.1 CDS EcE24377A_3392 NC_009801.1 3413447 3414049 R identified by glimmer; hypothetical protein complement(3413447..3414049) Escherichia coli E24377A 5588228 YP_001464390.1 CDS EcE24377A_3393 NC_009801.1 3414206 3414355 R identified by glimmer; hypothetical protein complement(3414206..3414355) Escherichia coli E24377A 5587203 YP_001464391.1 CDS EcE24377A_3394 NC_009801.1 3414352 3414462 R identified by glimmer; hypothetical protein complement(3414352..3414462) Escherichia coli E24377A 5589051 YP_001464392.1 CDS EcE24377A_3395 NC_009801.1 3414380 3415111 R identified by similarity to GB:CAD42091.1; hypothetical protein complement(3414380..3415111) Escherichia coli E24377A 5589612 YP_001464393.1 CDS EcE24377A_3396 NC_009801.1 3415155 3415274 R identified by glimmer; hypothetical protein complement(3415155..3415274) Escherichia coli E24377A 5586120 YP_001464394.1 CDS EcE24377A_3397 NC_009801.1 3415291 3415464 D identified by glimmer; hypothetical protein 3415291..3415464 Escherichia coli E24377A 5587691 YP_001464395.1 CDS EcE24377A_3398 NC_009801.1 3415659 3415754 D identified by glimmer; hypothetical protein 3415659..3415754 Escherichia coli E24377A 5587952 YP_001464396.1 CDS EcE24377A_3399 NC_009801.1 3416696 3417826 R identified by glimmer; hypothetical protein complement(3416696..3417826) Escherichia coli E24377A 5587648 YP_001464397.1 CDS EcE24377A_3400 NC_009801.1 3416900 3417037 D identified by glimmer; hypothetical protein 3416900..3417037 Escherichia coli E24377A 5590467 YP_001464398.1 CDS EcE24377A_3401 NC_009801.1 3417298 3417471 D identified by glimmer; hypothetical protein 3417298..3417471 Escherichia coli E24377A 5588889 YP_001464399.1 CDS EcE24377A_3402 NC_009801.1 3418011 3418895 D identified by match to protein family HMM PF01926; GTPase 3418011..3418895 Escherichia coli E24377A 5588761 YP_001464400.1 CDS EcE24377A_3403 NC_009801.1 3418914 3419069 D identified by glimmer; hypothetical protein 3418914..3419069 Escherichia coli E24377A 5590563 YP_001464401.1 CDS EcE24377A_3405 NC_009801.1 3419098 3419778 D identified by match to protein family HMM PF08279; hypothetical protein 3419098..3419778 Escherichia coli E24377A 5586235 YP_001464402.1 CDS EcE24377A_3404 NC_009801.1 3419662 3419793 R identified by glimmer; hypothetical protein complement(3419662..3419793) Escherichia coli E24377A 5587904 YP_001464403.1 CDS EcE24377A_3406 NC_009801.1 3419821 3420603 D identified by glimmer; hypothetical protein 3419821..3420603 Escherichia coli E24377A 5589136 YP_001464404.1 CDS EcE24377A_3407 NC_009801.1 3420609 3420842 D identified by match to protein family HMM PF06006; hypothetical protein 3420609..3420842 Escherichia coli E24377A 5586435 YP_001464405.1 CDS EcE24377A_3408 NC_009801.1 3420932 3421750 D identified by match to protein family HMM PF06067; hypothetical protein 3420932..3421750 Escherichia coli E24377A 5586452 YP_001464406.1 CDS EcE24377A_3409 NC_009801.1 3421842 3422327 D identified by match to protein family HMM PF03230; antirestriction protein 3421842..3422327 Escherichia coli E24377A 5589238 YP_001464407.1 CDS EcE24377A_3410 NC_009801.1 3422343 3422819 D identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608; RadC family DNA repair protein 3422343..3422819 Escherichia coli E24377A 5586311 YP_001464408.1 CDS EcE24377A_3411 NC_009801.1 3422906 3423127 D identified by match to protein family HMM PF06174; hypothetical protein 3422906..3423127 Escherichia coli E24377A 5589462 YP_001464409.1 CDS EcE24377A_3412 NC_009801.1 3423207 3423575 D identified by similarity to GB:AAP18296.1; match to protein family HMM PF06154; hypothetical protein 3423207..3423575 Escherichia coli E24377A 5590381 YP_001464410.1 CDS EcE24377A_3413 NC_009801.1 3423665 3424042 D identified by match to protein family HMM PF06755; hypothetical protein 3423665..3424042 Escherichia coli E24377A 5588996 YP_001464411.1 CDS EcE24377A_3414 NC_009801.1 3424039 3424527 D identified by similarity to GB:ABB61173.1; hypothetical protein 3424039..3424527 Escherichia coli E24377A 5589786 YP_001464412.1 CDS EcE24377A_3415 NC_009801.1 3424494 3424736 D identified by match to protein family HMM PF06117; hypothetical protein 3424494..3424736 Escherichia coli E24377A 5588149 YP_001464413.1 CDS EcE24377A_3416 NC_009801.1 3424821 3425666 D identified by similarity to GB:BAB34832.1; hypothetical protein 3424821..3425666 Escherichia coli E24377A 5587412 YP_001464414.1 CDS EcE24377A_3417 NC_009801.1 3426123 3427070 D identified by similarity to GB:CAE16642.1; match to protein family HMM PF08843; hypothetical protein 3426123..3427070 Escherichia coli E24377A 5588913 YP_001464415.1 CDS gspM NC_009801.1 3427425 3427961 R identified by similarity to SP:P41851; match to protein family HMM PF04612; general secretion pathway protein YghD complement(3427425..3427961) Escherichia coli E24377A 5586708 YP_001464416.1 CDS gspL NC_009801.1 3427963 3429141 R similar to general secretory pathway protein L; GspL-like protein complement(3427963..3429141) Escherichia coli E24377A 5587276 YP_001464417.1 CDS gspK NC_009801.1 3429138 3430115 R identified by match to protein family HMM PF03934; general secretion pathway protein K complement(3429138..3430115) Escherichia coli E24377A 5589996 YP_001464418.1 CDS gspJ NC_009801.1 3430118 3430717 R identified by match to protein family HMM PF07963; match to protein family HMM TIGR01711; match to protein family HMM TIGR02532; general secretion pathway protein J complement(3430118..3430717) Escherichia coli E24377A 5587390 YP_001464419.1 CDS gspI NC_009801.1 3430714 3431085 R identified by match to protein family HMM PF02501; match to protein family HMM PF07963; match to protein family HMM TIGR01707; match to protein family HMM TIGR02532; general secretion pathway protein I complement(3430714..3431085) Escherichia coli E24377A 5588351 YP_001464420.1 CDS gspH NC_009801.1 3431082 3431645 R identified by match to protein family HMM PF07963; match to protein family HMM TIGR01708; match to protein family HMM TIGR02532; general secretion pathway protein H complement(3431082..3431645) Escherichia coli E24377A 5587607 YP_001464421.1 CDS gspG NC_009801.1 3431649 3432104 R identified by match to protein family HMM PF07963; match to protein family HMM PF08334; match to protein family HMM TIGR01710; match to protein family HMM TIGR02532; general secretion pathway protein G complement(3431649..3432104) Escherichia coli E24377A 5587857 YP_001464422.1 CDS gspF NC_009801.1 3432121 3433344 R identified by match to protein family HMM PF00482; match to protein family HMM TIGR02120; general secretion pathway protein F complement(3432121..3433344) Escherichia coli E24377A 5586655 YP_001464423.1 CDS gspE NC_009801.1 3433344 3434837 R identified by match to protein family HMM PF00437; match to protein family HMM TIGR02533; general secretory pathway protein E complement(3433344..3434837) Escherichia coli E24377A 5588322 YP_001464424.1 CDS gspD NC_009801.1 3434837 3436897 R identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02517; general secretion pathway protein D complement(3434837..3436897) Escherichia coli E24377A 5588088 YP_001464425.1 CDS gspC NC_009801.1 3436927 3437886 R part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm; type II secretion protein GspC complement(3436927..3437886) Escherichia coli E24377A 5590427 YP_001464426.1 CDS EcE24377A_3429 NC_009801.1 3437904 3438314 R lipoprotein complement(3437904..3438314) Escherichia coli E24377A 5589346 YP_001464427.1 CDS EcE24377A_3430 NC_009801.1 3438380 3439189 R identified by similarity to SP:P31712; match to protein family HMM PF01478; match to protein family HMM PF06750; type IV prepilin peptidase complement(3438380..3439189) Escherichia coli E24377A 5587346 YP_001464428.1 CDS EcE24377A_3431 NC_009801.1 3439213 3439314 D identified by glimmer; hypothetical protein 3439213..3439314 Escherichia coli E24377A 5587456 YP_001464429.1 CDS EcE24377A_3432 NC_009801.1 3439337 3443857 R identified by glimmer; hypothetical protein complement(3439337..3443857) Escherichia coli E24377A 5590611 YP_001464430.1 CDS EcE24377A_3433 NC_009801.1 3444053 3444361 D identified by glimmer; hypothetical protein 3444053..3444361 Escherichia coli E24377A 5589159 YP_001464431.1 CDS glcA NC_009801.1 3444389 3446071 R identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795; glycolate transporter complement(3444389..3446071) Escherichia coli E24377A 5589399 YP_001464432.1 CDS glcB NC_009801.1 3446427 3448598 R catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G complement(3446427..3448598) Escherichia coli E24377A 5590624 YP_001464433.1 CDS EcE24377A_3436 NC_009801.1 3448620 3449024 R identified by match to protein family HMM PF03928; hypothetical protein complement(3448620..3449024) Escherichia coli E24377A 5587499 YP_001464434.1 CDS glcF NC_009801.1 3449029 3450252 R identified by similarity to SP:P52074; match to protein family HMM PF00037; match to protein family HMM PF02754; glycolate oxidase iron-sulfur subunit complement(3449029..3450252) Escherichia coli E24377A 5589075 YP_001464435.1 CDS glcE NC_009801.1 3450263 3451315 R identified by match to protein family HMM PF01565; glycolate oxidase FAD binding subunit complement(3450263..3451315) Escherichia coli E24377A 5587191 YP_001464436.1 CDS glcD NC_009801.1 3451315 3452805 R identified by similarity to SP:P52075; match to protein family HMM PF01565; match to protein family HMM PF02913; match to protein family HMM TIGR00387; glycolate oxidase subunit GlcD complement(3451315..3452805) Escherichia coli E24377A 5587883 YP_001464437.1 CDS glcC NC_009801.1 3453065 3453829 D identified by similarity to SP:P0ACL5; match to protein family HMM PF00392; match to protein family HMM PF07729; DNA-binding transcriptional regulator GlcC 3453065..3453829 Escherichia coli E24377A 5589190 YP_001464438.1 CDS EcE24377A_3441 NC_009801.1 3453836 3454978 R identified by glimmer; hypothetical protein complement(3453836..3454978) Escherichia coli E24377A 5587288 YP_001464439.1 CDS EcE24377A_3442 NC_009801.1 3455340 3457070 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3455340..3457070 Escherichia coli E24377A 5590602 YP_001464440.1 CDS EcE24377A_3443 NC_009801.1 3457067 3457981 D identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF05368; match to protein family HMM PF07993; NAD dependent epimerase/dehydratase 3457067..3457981 Escherichia coli E24377A 5590493 YP_001464441.1 CDS EcE24377A_3444 NC_009801.1 3458013 3458261 D identified by match to protein family HMM PF00550; acyl carrier protein 3458013..3458261 Escherichia coli E24377A 5589028 YP_001464442.1 CDS EcE24377A_3445 NC_009801.1 3458261 3459433 D identified by match to protein family HMM PF00155; match to protein family HMM PF00202; class I/II aminotransferase 3458261..3459433 Escherichia coli E24377A 5586319 YP_001464443.1 CDS EcE24377A_3446 NC_009801.1 3459469 3460548 R identified by match to protein family HMM PF03739; YjgP/YjgQ permease complement(3459469..3460548) Escherichia coli E24377A 5590830 YP_001464444.1 CDS EcE24377A_3447 NC_009801.1 3460545 3461615 R identified by match to protein family HMM PF03739; YjgP/YjgQ permease complement(3460545..3461615) Escherichia coli E24377A 5586011 YP_001464445.1 CDS EcE24377A_3448 NC_009801.1 3461646 3462206 R identified by match to protein family HMM TIGR01626; hypothetical protein complement(3461646..3462206) Escherichia coli E24377A 5587102 YP_001464446.1 CDS EcE24377A_3449 NC_009801.1 3462218 3463042 R identified by similarity to GB:AAN82163.1; hypothetical protein complement(3462218..3463042) Escherichia coli E24377A 5589001 YP_001464447.1 CDS EcE24377A_3450 NC_009801.1 3463042 3464391 R identified by match to protein family HMM PF01943; polysaccharide biosynthesis protein complement(3463042..3464391) Escherichia coli E24377A 5587385 YP_001464448.1 CDS EcE24377A_3451 NC_009801.1 3464437 3465195 R identified by similarity to GB:AAV89941.1; hypothetical protein complement(3464437..3465195) Escherichia coli E24377A 5589353 YP_001464449.1 CDS EcE24377A_3452 NC_009801.1 3465227 3465940 R lipoprotein complement(3465227..3465940) Escherichia coli E24377A 5590640 YP_001464450.1 CDS EcE24377A_3453 NC_009801.1 3466114 3466806 D hypothetical protein 3466114..3466806 Escherichia coli E24377A 5586889 YP_001464451.1 CDS pitB NC_009801.1 3466855 3468354 R identified by match to protein family HMM PF01384; low-affinity inorganic phosphate transporter 2 complement(3466855..3468354) Escherichia coli E24377A 5587830 YP_001464452.1 CDS gsp NC_009801.1 3468646 3470505 R catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase complement(3468646..3470505) Escherichia coli E24377A 5587475 YP_001464453.1 CDS EcE24377A_3456 NC_009801.1 3470710 3471576 D YghU; B2989; one of eight glutathione transferases from E. coli; glutathione S-transferase 3470710..3471576 Escherichia coli E24377A 5590289 YP_001464454.1 CDS EcE24377A_3457 NC_009801.1 3471876 3472856 D identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 3471876..3472856 Escherichia coli E24377A 5590618 YP_001464455.1 CDS EcE24377A_3459 NC_009801.1 3472871 3472999 D identified by glimmer; hypothetical protein 3472871..3472999 Escherichia coli E24377A 5588475 YP_001464456.1 CDS hybG NC_009801.1 3472978 3473226 R identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074; hydrogenase 2 accessory protein HypG complement(3472978..3473226) Escherichia coli E24377A 5589577 YP_001464457.1 CDS hypA2 NC_009801.1 3473239 3473580 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF complement(3473239..3473580) Escherichia coli E24377A 5589172 YP_001464458.1 CDS hybE NC_009801.1 3473573 3474061 R hydrogenase 2-specific chaperone complement(3473573..3474061) Escherichia coli E24377A 5590432 YP_001464459.1 CDS hybD NC_009801.1 3474054 3474548 R protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase complement(3474054..3474548) Escherichia coli E24377A 5590573 YP_001464460.1 CDS hybC NC_009801.1 3474548 3476251 R involved in hydrogen uptake; hydrogenase 2 large subunit complement(3474548..3476251) Escherichia coli E24377A 5586442 YP_001464461.1 CDS hybB NC_009801.1 3476248 3477426 R HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit complement(3476248..3477426) Escherichia coli E24377A 5588908 YP_001464462.1 CDS hybA NC_009801.1 3477416 3478402 R Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA complement(3477416..3478402) Escherichia coli E24377A 5588531 YP_001464463.1 CDS EcE24377A_3467 NC_009801.1 3477530 3478444 D identified by glimmer; hypothetical protein 3477530..3478444 Escherichia coli E24377A 5587932 YP_001464464.1 CDS hyb0 NC_009801.1 3478405 3479523 R involved in hydrogen uptake; hydrogenase 2 small subunit complement(3478405..3479523) Escherichia coli E24377A 5588909 YP_001464465.1 CDS EcE24377A_3468 NC_009801.1 3479712 3479999 R identified by similarity to SP:P64577; hypothetical protein complement(3479712..3479999) Escherichia coli E24377A 5590875 YP_001464466.1 CDS EcE24377A_3469 NC_009801.1 3480118 3481005 R identified by match to protein family HMM PF01738; match to protein family HMM PF08840; dienelactone hydrolase complement(3480118..3481005) Escherichia coli E24377A 5586223 YP_001464467.1 CDS EcE24377A_3470 NC_009801.1 3481163 3482203 D identified by match to protein family HMM PF00248; aldo/keto reductase 3481163..3482203 Escherichia coli E24377A 5590607 YP_001464468.1 CDS EcE24377A_3471 NC_009801.1 3482243 3482737 R identified by match to protein family HMM PF03350; match to protein family HMM TIGR00645; hypothetical protein complement(3482243..3482737) Escherichia coli E24377A 5586622 YP_001464469.1 CDS EcE24377A_3472 NC_009801.1 3482928 3483812 D identified by match to protein family HMM PF00106; oxidoreductase 3482928..3483812 Escherichia coli E24377A 5588016 YP_001464470.1 CDS EcE24377A_3473 NC_009801.1 3483885 3484076 R identified by glimmer; hypothetical protein complement(3483885..3484076) Escherichia coli E24377A 5588075 YP_001464471.1 CDS exbD NC_009801.1 3484084 3484509 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD complement(3484084..3484509) Escherichia coli E24377A 5587544 YP_001464472.1 CDS exbB NC_009801.1 3484516 3485250 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB complement(3484516..3485250) Escherichia coli E24377A 5588894 YP_001464473.1 CDS metC NC_009801.1 3485502 3486689 D catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3485502..3486689 Escherichia coli E24377A 5590712 YP_001464474.1 CDS EcE24377A_3477 NC_009801.1 3486829 3487488 D identified by similarity to SP:P0AA60; match to protein family HMM PF09335; hypothetical protein 3486829..3487488 Escherichia coli E24377A 5585932 YP_001464475.1 CDS EcE24377A_3478 NC_009801.1 3487528 3488655 R identified by match to protein family HMM PF00165; match to protein family HMM PF06719; AraC family transcriptional regulator complement(3487528..3488655) Escherichia coli E24377A 5587362 YP_001464476.1 CDS yqhD NC_009801.1 3488621 3489784 D identified by similarity to SP:Q46856; match to protein family HMM PF00465; alcohol dehydrogenase 3488621..3489784 Escherichia coli E24377A 5588639 YP_001464477.1 CDS dkgA NC_009801.1 3489889 3490716 D methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3489889..3490716 Escherichia coli E24377A 5586279 YP_001464478.1 CDS EcE24377A_3481 NC_009801.1 3490860 3490952 R identified by glimmer; hypothetical protein complement(3490860..3490952) Escherichia coli E24377A 5589125 YP_001464479.1 CDS EcE24377A_3482 NC_009801.1 3490916 3491842 D hypothetical protein 3490916..3491842 Escherichia coli E24377A 5586792 YP_001464480.1 CDS EcE24377A_3483 NC_009801.1 3491893 3492150 D outer membrane lipoprotein 3491893..3492150 Escherichia coli E24377A 5589057 YP_001464481.1 CDS EcE24377A_3484 NC_009801.1 3492193 3494412 R identified by match to protein family HMM PF04055; match to protein family HMM PF08497; hypothetical protein complement(3492193..3494412) Escherichia coli E24377A 5587135 YP_001464482.1 CDS sufI NC_009801.1 3494523 3495935 R identified by similarity to SP:P26648; match to protein family HMM PF07731; match to protein family HMM PF07732; match to protein family HMM TIGR01409; repressor protein for FtsI complement(3494523..3495935) Escherichia coli E24377A 5586593 YP_001464483.1 CDS plsC NC_009801.1 3496010 3496747 R identified by similarity to SP:P26647; match to protein family HMM PF01553; match to protein family HMM TIGR00530; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(3496010..3496747) Escherichia coli E24377A 5588525 YP_001464484.1 CDS parC NC_009801.1 3496980 3499238 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(3496980..3499238) Escherichia coli E24377A 5588900 YP_001464485.1 CDS EcE24377A_3488 NC_009801.1 3499784 3500266 R identified by match to protein family HMM PF06445; transcription activator effector binding domain/DNA gyrase inhibitor domain-containing protein complement(3499784..3500266) Escherichia coli E24377A 5589712 YP_001464486.1 CDS EcE24377A_3489 NC_009801.1 3500319 3500711 R identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156; hypothetical protein complement(3500319..3500711) Escherichia coli E24377A 5586445 YP_001464487.1 CDS qseB NC_009801.1 3500863 3501510 D response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3500863..3501510 Escherichia coli E24377A 5589404 YP_001464488.1 CDS qseC NC_009801.1 3501507 3502856 D identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor protein QseC 3501507..3502856 Escherichia coli E24377A 5589810 YP_001464489.1 CDS mdaB NC_009801.1 3503553 3504134 D identified by similarity to SP:P0AEY5; match to protein family HMM PF02525; modulator of drug activity B 3503553..3504134 Escherichia coli E24377A 5590265 YP_001464490.1 CDS ygiN NC_009801.1 3504165 3504479 D identified by similarity to PDB:1R6Y_A; match to protein family HMM PF03992; quinol monooxygenase YgiN 3504165..3504479 Escherichia coli E24377A 5589085 YP_001464491.1 CDS parE NC_009801.1 3504527 3506419 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(3504527..3506419) Escherichia coli E24377A 5590460 YP_001464492.1 CDS yqiA NC_009801.1 3506448 3507029 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase complement(3506448..3507029) Escherichia coli E24377A 5589424 YP_001464493.1 CDS icc NC_009801.1 3507029 3507856 R identified by match to protein family HMM PF00149; match to protein family HMM PF08413; cyclic 3',5'-adenosine monophosphate phosphodiesterase complement(3507029..3507856) Escherichia coli E24377A 5588515 YP_001464494.1 CDS EcE24377A_3497 NC_009801.1 3507881 3508303 R identified by similarity to SP:P0ADV0; match to protein family HMM PF06853; hypothetical protein complement(3507881..3508303) Escherichia coli E24377A 5590780 YP_001464495.1 CDS nudF NC_009801.1 3508304 3508933 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase complement(3508304..3508933) Escherichia coli E24377A 5588785 YP_001464496.1 CDS tolC NC_009801.1 3509132 3510619 D trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3509132..3510619 Escherichia coli E24377A 5587492 YP_001464497.1 CDS EcE24377A_3500 NC_009801.1 3510619 3510879 D identified by similarity to GB:ABB63213.1; hypothetical protein 3510619..3510879 Escherichia coli E24377A 5589242 YP_001464498.1 CDS EcE24377A_3501 NC_009801.1 3510767 3511438 D identified by similarity to GB:ABG71111.1; hypothetical protein 3510767..3511438 Escherichia coli E24377A 5590389 YP_001464499.1 CDS EcE24377A_3502 NC_009801.1 3511444 3512604 D identified by match to protein family HMM PF03738; glutathionylspermidine synthase 3511444..3512604 Escherichia coli E24377A 5586649 YP_001464500.1 CDS EcE24377A_3503 NC_009801.1 3512642 3513457 R seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein complement(3512642..3513457) Escherichia coli E24377A 5590598 YP_001464501.1 CDS zupT NC_009801.1 3513573 3514346 D identified by match to protein family HMM PF02535; zinc transporter ZupT 3513573..3514346 Escherichia coli E24377A 5590025 YP_001464502.1 CDS EcE24377A_3505 NC_009801.1 3514404 3514598 R identified by similarity to GB:AAG58180.1; hypothetical protein complement(3514404..3514598) Escherichia coli E24377A 5590307 YP_001464503.1 CDS ribB NC_009801.1 3514835 3515488 R DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(3514835..3515488) Escherichia coli E24377A 5590495 YP_001464504.1 CDS EcE24377A_3507 NC_009801.1 3515802 3516152 D identified by match to protein family HMM PF04380; hypothetical protein 3515802..3516152 Escherichia coli E24377A 5586369 YP_001464505.1 CDS EcE24377A_3508 NC_009801.1 3516435 3516986 D identified by match to protein family HMM PF00419; fimbrial protein 3516435..3516986 Escherichia coli E24377A 5586151 YP_001464506.1 CDS EcE24377A_3509 NC_009801.1 3517046 3519550 D identified by match to protein family HMM PF00577; fimbrial usher protein 3517046..3519550 Escherichia coli E24377A 5589191 YP_001464507.1 CDS EcE24377A_3510 NC_009801.1 3519566 3520315 D identified by match to protein family HMM PF00345; periplasmic pilus chaperone family protein 3519566..3520315 Escherichia coli E24377A 5587415 YP_001464508.1 CDS EcE24377A_3511 NC_009801.1 3520317 3521381 D identified by similarity to GB:AAZ89767.1; hypothetical protein 3520317..3521381 Escherichia coli E24377A 5587714 YP_001464509.1 CDS glgS NC_009801.1 3521424 3521624 R Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS complement(3521424..3521624) Escherichia coli E24377A 5588770 YP_001464510.1 CDS EcE24377A_3513 NC_009801.1 3521893 3522522 D identified by match to protein family HMM PF07290; inner membrane protein 3521893..3522522 Escherichia coli E24377A 5587603 YP_001464511.1 CDS EcE24377A_3514 NC_009801.1 3522549 3524210 D identified by match to protein family HMM PF01145; hypothetical protein 3522549..3524210 Escherichia coli E24377A 5588974 YP_001464512.1 CDS hldE NC_009801.1 3525004 3526437 R catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase complement(3525004..3526437) Escherichia coli E24377A 5590809 YP_001464513.1 CDS glnE NC_009801.1 3526485 3529325 R catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase complement(3526485..3529325) Escherichia coli E24377A 5587885 YP_001464514.1 CDS EcE24377A_3517 NC_009801.1 3529348 3530649 R identified by match to protein family HMM PF01928; match to protein family HMM PF05235; adenylate cyclase complement(3529348..3530649) Escherichia coli E24377A 5586610 YP_001464515.1 CDS EcE24377A_3518 NC_009801.1 3530891 3531511 D signal transduction protein 3530891..3531511 Escherichia coli E24377A 5586143 YP_001464516.1 CDS cca NC_009801.1 3531575 3532813 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3531575..3532813 Escherichia coli E24377A 5589556 YP_001464517.1 CDS uppP NC_009801.1 3532976 3533797 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase complement(3532976..3533797) Escherichia coli E24377A 5589698 YP_001464518.1 CDS folB NC_009801.1 3533887 3534255 R catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase complement(3533887..3534255) Escherichia coli E24377A 5589115 YP_001464519.1 CDS EcE24377A_3522 NC_009801.1 3534360 3534977 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 3534360..3534977 Escherichia coli E24377A 5587348 YP_001464520.1 CDS EcE24377A_3523 NC_009801.1 3534990 3535922 R activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR complement(3534990..3535922) Escherichia coli E24377A 5589029 YP_001464521.1 CDS EcE24377A_3524 NC_009801.1 3535941 3536075 D identified by glimmer; hypothetical protein 3535941..3536075 Escherichia coli E24377A 5587014 YP_001464522.1 CDS ddtA NC_009801.1 3536129 3537040 D Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3536129..3537040 Escherichia coli E24377A 5587616 YP_001464523.1 CDS ttdB NC_009801.1 3537037 3537642 D Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3537037..3537642 Escherichia coli E24377A 5590824 YP_001464524.1 CDS EcE24377A_3527 NC_009801.1 3537691 3539154 D identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785; anion transporter 3537691..3539154 Escherichia coli E24377A 5590565 YP_001464525.1 CDS gcp NC_009801.1 3539197 3540210 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(3539197..3540210) Escherichia coli E24377A 5588002 YP_001464526.1 CDS rpsU NC_009801.1 3540448 3540663 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3540448..3540663 Escherichia coli E24377A 5589126 YP_001464527.1 CDS dnaG NC_009801.1 3540774 3542519 D synthesizes RNA primers at the replication forks; DNA primase 3540774..3542519 Escherichia coli E24377A 5587754 YP_001464528.1 CDS rpoD NC_009801.1 3542714 3544555 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3542714..3544555 Escherichia coli E24377A 5589910 YP_001464529.1 CDS mug NC_009801.1 3544633 3545139 R identified by similarity to SP:P0A9H1; match to protein family HMM PF03167; G/U mismatch-specific DNA glycosylase complement(3544633..3545139) Escherichia coli E24377A 5590035 YP_001464530.1 CDS EcE24377A_3535 NC_009801.1 3545393 3546157 R identified by match to protein family HMM PF04954; match to protein family HMM PF08021; siderophore-interacting protein complement(3545393..3546157) Escherichia coli E24377A 5586284 YP_001464531.1 CDS EcE24377A_3536 NC_009801.1 3546208 3546315 D identified by glimmer; hypothetical protein 3546208..3546315 Escherichia coli E24377A 5589218 YP_001464532.1 CDS EcE24377A_3537 NC_009801.1 3546434 3547057 D identified by match to protein family HMM PF03551; PadR family transcriptional regulator 3546434..3547057 Escherichia coli E24377A 5590000 YP_001464533.1 CDS aer NC_009801.1 3547211 3548731 R identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF08447; match to protein family HMM TIGR00229; aerotaxis receptor complement(3547211..3548731) Escherichia coli E24377A 5585923 YP_001464534.1 CDS EcE24377A_3539 NC_009801.1 3548922 3549035 R identified by glimmer; hypothetical protein complement(3548922..3549035) Escherichia coli E24377A 5587056 YP_001464535.1 CDS rocD NC_009801.1 3549239 3550528 D catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3549239..3550528 Escherichia coli E24377A 5586935 YP_001464536.1 CDS EcE24377A_3541 NC_009801.1 3550570 3550902 R identified by match to protein family HMM PF01588; hypothetical protein complement(3550570..3550902) Escherichia coli E24377A 5589883 YP_001464537.1 CDS ebgR NC_009801.1 3551121 3552104 D identified by similarity to SP:P06846; match to protein family HMM PF00356; match to protein family HMM PF00532; DNA-binding transcriptional repressor EbgR 3551121..3552104 Escherichia coli E24377A 5587470 YP_001464538.1 CDS ebgA NC_009801.1 3552288 3555380 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3552288..3555380 Escherichia coli E24377A 5587097 YP_001464539.1 CDS ebgC NC_009801.1 3555377 3555826 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3555377..3555826 Escherichia coli E24377A 5587854 YP_001464540.1 CDS EcE24377A_3545 NC_009801.1 3555889 3557322 D identified by match to protein family HMM PF00324; amino acid permease 3555889..3557322 Escherichia coli E24377A 5589174 YP_001464541.1 CDS EcE24377A_3546 NC_009801.1 3557456 3558526 D identified by similarity to GB:AAZ89711.1; hypothetical protein 3557456..3558526 Escherichia coli E24377A 5590806 YP_001464542.1 CDS EcE24377A_3547 NC_009801.1 3558543 3560894 D identified by similarity to SP:P42592; glycosyl hydrolase 3558543..3560894 Escherichia coli E24377A 5586281 YP_001464543.1 CDS fadH NC_009801.1 3561220 3563238 D identified by similarity to SP:P42593; match to protein family HMM PF00724; match to protein family HMM PF01266; match to protein family HMM PF07992; 2,4-dienoyl-CoA reductase 3561220..3563238 Escherichia coli E24377A 5588147 YP_001464544.1 CDS EcE24377A_3549 NC_009801.1 3563283 3563699 R identified by match to protein family HMM PF01381; helix-turn-helix DNA-binding domain-containing protein complement(3563283..3563699) Escherichia coli E24377A 5589630 YP_001464545.1 CDS EcE24377A_3550 NC_009801.1 3563696 3563866 R identified by similarity to GB:AAN82286.1; hypothetical protein complement(3563696..3563866) Escherichia coli E24377A 5590790 YP_001464546.1 CDS EcE24377A_3551 NC_009801.1 3563970 3565106 R identified by match to protein family HMM PF05175; match to protein family HMM PF08242; methyltransferase complement(3563970..3565106) Escherichia coli E24377A 5586732 YP_001464547.1 CDS EcE24377A_3552 NC_009801.1 3565191 3565694 D identified by similarity to SP:P42597; match to protein family HMM PF01863; hypothetical protein 3565191..3565694 Escherichia coli E24377A 5589985 YP_001464548.1 CDS EcE24377A_3553 NC_009801.1 3565771 3566454 D identified by match to protein family HMM PF02698; SanA protein 3565771..3566454 Escherichia coli E24377A 5588535 YP_001464549.1 CDS EcE24377A_3554 NC_009801.1 3566533 3567519 D identified by match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase, NAD binding 3566533..3567519 Escherichia coli E24377A 5588617 YP_001464550.1 CDS alx NC_009801.1 3567802 3568767 D identified by similarity to SP:P42601; match to protein family HMM PF03741; protein Alx 3567802..3568767 Escherichia coli E24377A 5590742 YP_001464551.1 CDS EcE24377A_3556 NC_009801.1 3568876 3569178 D identified by glimmer; hypothetical protein 3568876..3569178 Escherichia coli E24377A 5587403 YP_001464552.1 CDS sstT NC_009801.1 3569383 3570627 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3569383..3570627 Escherichia coli E24377A 5587934 YP_001464553.1 CDS EcE24377A_3558 NC_009801.1 3570632 3571183 R inner membrane protein complement(3570632..3571183) Escherichia coli E24377A 5589038 YP_001464554.1 CDS uxaA NC_009801.1 3571266 3572753 R identified by similarity to SP:P42604; match to protein family HMM PF04295; match to protein family HMM PF08666; altronate dehydratase complement(3571266..3572753) Escherichia coli E24377A 5589597 YP_001464555.1 CDS uxaC NC_009801.1 3572768 3574180 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(3572768..3574180) Escherichia coli E24377A 5589846 YP_001464556.1 CDS EcE24377A_3561 NC_009801.1 3574663 3575961 D identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893; hexuronate transporter 3574663..3575961 Escherichia coli E24377A 5586588 YP_001464557.1 CDS EcE24377A_3562 NC_009801.1 3576049 3577137 R pilus biogenesis initiator protein complement(3576049..3577137) Escherichia coli E24377A 5587527 YP_001464558.1 CDS EcE24377A_3563 NC_009801.1 3577134 3579836 R hypothetical protein complement(3577134..3579836) Escherichia coli E24377A 5590766 YP_001464559.1 CDS EcE24377A_3564 NC_009801.1 3579910 3580410 R identified by match to protein family HMM PF04449; CS1 type fimbrial major subunit complement(3579910..3580410) Escherichia coli E24377A 5587519 YP_001464560.1 CDS EcE24377A_3565 NC_009801.1 3580440 3581156 R hypothetical protein complement(3580440..3581156) Escherichia coli E24377A 5589785 YP_001464561.1 CDS exuR NC_009801.1 3581452 3582228 D regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3581452..3582228 Escherichia coli E24377A 5590003 YP_001464562.1 CDS EcE24377A_3567 NC_009801.1 3582573 3583235 D identified by similarity to SP:P0AA63; match to protein family HMM PF09335; inner membrane protein 3582573..3583235 Escherichia coli E24377A 5590092 YP_001464563.1 CDS EcE24377A_3569 NC_009801.1 3583239 3583622 D identified by similarity to GB:AAZ89832.1; hypothetical protein 3583239..3583622 Escherichia coli E24377A 5587954 YP_001464564.1 CDS EcE24377A_3568 NC_009801.1 3583607 3583702 R identified by glimmer; hypothetical protein complement(3583607..3583702) Escherichia coli E24377A 5586627 YP_001464565.1 CDS EcE24377A_3570 NC_009801.1 3583769 3584137 D identified by similarity to SP:P42616; match to protein family HMM PF06476; hypothetical protein 3583769..3584137 Escherichia coli E24377A 5587099 YP_001464566.1 CDS EcE24377A_3571 NC_009801.1 3584175 3584480 D identified by similarity to GB:CAD07753.1; match to protein family HMM PF05957; hypothetical protein 3584175..3584480 Escherichia coli E24377A 5589874 YP_001464567.1 CDS EcE24377A_3572 NC_009801.1 3584483 3584887 D identified by similarity to GB:ABE08983.1; hypothetical protein 3584483..3584887 Escherichia coli E24377A 5587152 YP_001464568.1 CDS EcE24377A_3573 NC_009801.1 3584877 3585176 D identified by similarity to GB:ABB63285.1; hypothetical protein 3584877..3585176 Escherichia coli E24377A 5588853 YP_001464569.1 CDS EcE24377A_3574 NC_009801.1 3585362 3585754 D identified by match to protein family HMM PF07681; inner membrane protein YqjF 3585362..3585754 Escherichia coli E24377A 5587229 YP_001464570.1 CDS EcE24377A_3575 NC_009801.1 3585824 3586810 D hypothetical protein 3585824..3586810 Escherichia coli E24377A 5586997 YP_001464571.1 CDS EcE24377A_3576 NC_009801.1 3586850 3586945 D identified by glimmer; hypothetical protein 3586850..3586945 Escherichia coli E24377A 5587522 YP_001464572.1 CDS EcE24377A_3577 NC_009801.1 3587082 3587468 D identified by match to protein family HMM PF05656; inner membrane protein YhaH 3587082..3587468 Escherichia coli E24377A 5587289 YP_001464573.1 CDS EcE24377A_3578 NC_009801.1 3587561 3587653 D identified by glimmer; hypothetical protein 3587561..3587653 Escherichia coli E24377A 5586528 YP_001464574.1 CDS EcE24377A_3579 NC_009801.1 3587710 3588066 D identified by similarity to SP:P64592; match to protein family HMM PF05656; inner membrane protein 3587710..3588066 Escherichia coli E24377A 5587786 YP_001464575.1 CDS EcE24377A_3580 NC_009801.1 3588117 3589013 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(3588117..3589013) Escherichia coli E24377A 5588685 YP_001464576.1 CDS EcE24377A_3581 NC_009801.1 3589118 3589819 D identified by match to protein family HMM PF02678; pirin 3589118..3589819 Escherichia coli E24377A 5586237 YP_001464577.1 CDS EcE24377A_3583 NC_009801.1 3589842 3590006 D identified by similarity to GB:ABB63296.1; hypothetical protein 3589842..3590006 Escherichia coli E24377A 5588336 YP_001464578.1 CDS EcE24377A_3582 NC_009801.1 3589996 3590148 R identified by glimmer; hypothetical protein complement(3589996..3590148) Escherichia coli E24377A 5589058 YP_001464579.1 CDS EcE24377A_3584 NC_009801.1 3590218 3591528 R identified by match to protein family HMM PF06354; hypothetical protein complement(3590218..3591528) Escherichia coli E24377A 5588443 YP_001464580.1 CDS EcE24377A_3585 NC_009801.1 3591556 3592887 R identified by match to protein family HMM TIGR00814; serine transporter family protein complement(3591556..3592887) Escherichia coli E24377A 5587851 YP_001464581.1 CDS tdcG NC_009801.1 3593162 3594526 R identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; L-serine dehydratase tdcG complement(3593162..3594526) Escherichia coli E24377A 5587893 YP_001464582.1 CDS EcE24377A_3587 NC_009801.1 3594598 3594987 R identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; hypothetical protein complement(3594598..3594987) Escherichia coli E24377A 5588795 YP_001464583.1 CDS pflB1 NC_009801.1 3595001 3597295 R identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; formate acetyltransferase complement(3595001..3597295) Escherichia coli E24377A 5586576 YP_001464584.1 CDS tdcD NC_009801.1 3597329 3598537 R catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase complement(3597329..3598537) Escherichia coli E24377A 5587771 YP_001464585.1 CDS tdcC NC_009801.1 3598563 3599894 R involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC complement(3598563..3599894) Escherichia coli E24377A 5589804 YP_001464586.1 CDS tdcB NC_009801.1 3599916 3600905 R catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase complement(3599916..3600905) Escherichia coli E24377A 5590034 YP_001464587.1 CDS tdcA NC_009801.1 3601004 3601942 R regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA complement(3601004..3601942) Escherichia coli E24377A 5590149 YP_001464588.1 CDS tdcR NC_009801.1 3602257 3602475 D participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3602257..3602475 Escherichia coli E24377A 5586043 YP_001464589.1 CDS EcE24377A_3594 NC_009801.1 3602557 3602694 R identified by glimmer; hypothetical protein complement(3602557..3602694) Escherichia coli E24377A 5589244 YP_001464590.1 CDS EcE24377A_3595 NC_009801.1 3602710 3603270 D identified by glimmer; hypothetical protein 3602710..3603270 Escherichia coli E24377A 5590343 YP_001464591.1 CDS EcE24377A_3596 NC_009801.1 3603292 3604479 D identified by similarity to GB:BAB37424.1; hypothetical protein 3603292..3604479 Escherichia coli E24377A 5588145 YP_001464592.1 CDS EcE24377A_3599 NC_009801.1 3604540 3604704 D identified by similarity to GB:ABB67500.1; hypothetical protein 3604540..3604704 Escherichia coli E24377A 5589287 YP_001464593.1 CDS EcE24377A_3600 NC_009801.1 3604756 3604863 D identified by glimmer; hypothetical protein 3604756..3604863 Escherichia coli E24377A 5589582 YP_001464595.1 CDS garK NC_009801.1 3605502 3606647 R identified by similarity to SP:P23524; match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase complement(3605502..3606647) Escherichia coli E24377A 5589559 YP_001464596.1 CDS garR NC_009801.1 3606744 3607628 R catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase complement(3606744..3607628) Escherichia coli E24377A 5588960 YP_001464597.1 CDS garL NC_009801.1 3607664 3608434 R cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase complement(3607664..3608434) Escherichia coli E24377A 5589352 YP_001464598.1 CDS garP NC_009801.1 3608450 3609784 R identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893; galactarate permease GarP complement(3608450..3609784) Escherichia coli E24377A 5589562 YP_001464599.1 CDS EcE24377A_3606 NC_009801.1 3609771 3609884 D identified by glimmer; hypothetical protein 3609771..3609884 Escherichia coli E24377A 5587892 YP_001464600.1 CDS EcE24377A_3607 NC_009801.1 3609993 3610112 D identified by glimmer; hypothetical protein 3609993..3610112 Escherichia coli E24377A 5589879 YP_001464601.1 CDS garD NC_009801.1 3610159 3611730 D identified by similarity to SP:P39829; match to protein family HMM PF04295; match to protein family HMM PF08666; galactarate dehydratase 3610159..3611730 Escherichia coli E24377A 5586967 YP_001464602.1 CDS sohA NC_009801.1 3611879 3612214 D SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; regulator PrlF 3611879..3612214 Escherichia coli E24377A 5587743 YP_001464603.1 CDS EcE24377A_3610 NC_009801.1 3612214 3612678 D identified by similarity to GB:AAZ89862.1; hypothetical protein 3612214..3612678 Escherichia coli E24377A 5589554 YP_001464604.1 CDS EcE24377A_3611 NC_009801.1 3612733 3613542 R transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR complement(3612733..3613542) Escherichia coli E24377A 5587805 YP_001464605.1 CDS EcE24377A_3612 NC_009801.1 3613791 3615071 D identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810; D-tagatose-bisphosphate aldolase non-catalytic subunit 3613791..3615071 Escherichia coli E24377A 5587313 YP_001464606.1 CDS agaV NC_009801.1 3615094 3615567 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3615094..3615567 Escherichia coli E24377A 5590797 YP_001464607.1 CDS agaW NC_009801.1 3615578 3616357 D identified by match to protein family HMM PF03609; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3615578..3616357 Escherichia coli E24377A 5586879 YP_001464608.1 CDS agaE NC_009801.1 3616347 3617225 D identified by match to protein family HMM PF03613; PTS system N-acetylgalactosamine-specific, IID component 3616347..3617225 Escherichia coli E24377A 5587564 YP_001464609.1 CDS agaF NC_009801.1 3617243 3617677 D identified by similarity to GB:AAF81086.1; match to protein family HMM PF03610; PTS system mannose/sorbose-specific transporter subunit IIA 3617243..3617677 Escherichia coli E24377A 5588610 YP_001464610.1 CDS nagA2 NC_009801.1 3617674 3618807 D identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221; N-acetylglucosamine-6-phosphate deacetylase 3617674..3618807 Escherichia coli E24377A 5589127 YP_001464611.1 CDS EcE24377A_3618 NC_009801.1 3619157 3620311 D identified by match to protein family HMM PF01380; match to protein family HMM TIGR02815; AgaS family sugar isomerase 3619157..3620311 Escherichia coli E24377A 5590112 YP_001464612.1 CDS kbaY NC_009801.1 3620324 3621184 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3620324..3621184 Escherichia coli E24377A 5587992 YP_001464613.1 CDS agaB NC_009801.1 3621351 3621827 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3621351..3621827 Escherichia coli E24377A 5588353 YP_001464614.1 CDS agaC NC_009801.1 3621866 3622669 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3621866..3622669 Escherichia coli E24377A 5586234 YP_001464615.1 CDS agaD NC_009801.1 3622659 3623450 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 3622659..3623450 Escherichia coli E24377A 5587520 YP_001464616.1 CDS agaI NC_009801.1 3623451 3624206 D identified by match to protein family HMM PF01182; galactosamine-6-phosphate isomerase 3623451..3624206 Escherichia coli E24377A 5588476 YP_001464617.1 CDS EcE24377A_3624 NC_009801.1 3624606 3625190 D identified by match to protein family HMM PF00419; fimbrial protein 3624606..3625190 Escherichia coli E24377A 5590642 YP_001464618.1 CDS EcE24377A_3625 NC_009801.1 3625270 3625965 D identified by match to protein family HMM PF00345; match to protein family HMM PF02753; pili assembly chaperone protein 3625270..3625965 Escherichia coli E24377A 5586174 YP_001464619.1 CDS EcE24377A_3626 NC_009801.1 3625995 3628511 D identified by match to protein family HMM PF00577; fimbrial usher family protein 3625995..3628511 Escherichia coli E24377A 5587988 YP_001464620.1 CDS EcE24377A_3627 NC_009801.1 3628522 3629613 D fimbrial protein 3628522..3629613 Escherichia coli E24377A 5590358 YP_001464621.1 CDS EcE24377A_3628 NC_009801.1 3629656 3630516 R identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096; tetrapyrrole methylase complement(3629656..3630516) Escherichia coli E24377A 5588956 YP_001464622.1 CDS EcE24377A_3629 NC_009801.1 3630580 3632616 D identified by match to protein family HMM PF04348; lipoprotein 3630580..3632616 Escherichia coli E24377A 5589385 YP_001464623.1 CDS EcE24377A_3630 NC_009801.1 3632574 3632969 D identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252; hypothetical protein 3632574..3632969 Escherichia coli E24377A 5588776 YP_001464624.1 CDS diaA NC_009801.1 3632989 3633579 D Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3632989..3633579 Escherichia coli E24377A 5587615 YP_001464625.1 CDS EcE24377A_3632 NC_009801.1 3633589 3634164 D identified by match to protein family HMM PF04972; hypothetical protein 3633589..3634164 Escherichia coli E24377A 5589224 YP_001464626.1 CDS EcE24377A_3634 NC_009801.1 3635390 3636025 R identified by match to protein family HMM PF01370; NAD dependent epimerase/dehydratase complement(3635390..3636025) Escherichia coli E24377A 5587595 YP_001464627.1 CDS EcE24377A_3636 NC_009801.1 3636153 3636671 D identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382; PfpI family intracellular peptidase 3636153..3636671 Escherichia coli E24377A 5590554 YP_001464628.1 CDS EcE24377A_3635 NC_009801.1 3636651 3637094 R identified by similarity to GB:AAV78968.1; hypothetical protein complement(3636651..3637094) Escherichia coli E24377A 5589669 YP_001464629.1 CDS EcE24377A_3638 NC_009801.1 3637145 3637447 D identified by match to protein family HMM PF01541; GIY-YIG nuclease superfamily protein 3637145..3637447 Escherichia coli E24377A 5590865 YP_001464630.1 CDS EcE24377A_3637 NC_009801.1 3637434 3637937 R identified by match to protein family HMM PF00583; acetyltransferase complement(3637434..3637937) Escherichia coli E24377A 5590280 YP_001464631.1 CDS EcE24377A_3639 NC_009801.1 3637931 3638455 R identified by match to protein family HMM PF02036; sterol-binding protein complement(3637931..3638455) Escherichia coli E24377A 5589670 YP_001464632.1 CDS EcE24377A_3640 NC_009801.1 3638664 3639659 D identified by match to protein family HMM PF01136; U32 family peptidase 3638664..3639659 Escherichia coli E24377A 5590500 YP_001464633.1 CDS EcE24377A_3641 NC_009801.1 3639668 3640546 D identified by match to protein family HMM PF01136; U32 family peptidase 3639668..3640546 Escherichia coli E24377A 5588433 YP_001464634.1 CDS EcE24377A_3642 NC_009801.1 3640752 3641759 D identified by match to protein family HMM PF00296; hypothetical protein 3640752..3641759 Escherichia coli E24377A 5587077 YP_001464635.1 CDS mtr NC_009801.1 3641877 3643121 R tryptophan transporter of high affinity; tryptophan permease complement(3641877..3643121) Escherichia coli E24377A 5586318 YP_001464636.1 CDS deaD NC_009801.1 3643275 3645230 R participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD complement(3643275..3645230) Escherichia coli E24377A 5590031 YP_001464637.1 CDS EcE24377A_3646 NC_009801.1 3645304 3645459 D identified by glimmer; hypothetical protein 3645304..3645459 Escherichia coli E24377A 5586921 YP_001464638.1 CDS EcE24377A_3645 NC_009801.1 3645344 3646228 R lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI complement(3645344..3646228) Escherichia coli E24377A 5590329 YP_001464639.1 CDS EcE24377A_3648 NC_009801.1 3646328 3648496 D identified by glimmer; hypothetical protein 3646328..3648496 Escherichia coli E24377A 5585975 YP_001464640.1 CDS pnp NC_009801.1 3646337 3648472 R identified by similarity to SP:P05055; match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; polynucleotide phosphorylase complement(3646337..3648472) Escherichia coli E24377A 5588806 YP_001464641.1 CDS rpsO NC_009801.1 3648719 3648988 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(3648719..3648988) Escherichia coli E24377A 5588702 YP_001464642.1 CDS truB NC_009801.1 3649137 3650081 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(3649137..3650081) Escherichia coli E24377A 5589836 YP_001464643.1 CDS rbfA NC_009801.1 3650081 3650482 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(3650081..3650482) Escherichia coli E24377A 5588504 YP_001464644.1 CDS infB NC_009801.1 3650646 3653318 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(3650646..3653318) Escherichia coli E24377A 5586604 YP_001464645.1 CDS EcE24377A_3654 NC_009801.1 3653175 3654644 D identified by similarity to GB:AAW76474.1; hypothetical protein 3653175..3654644 Escherichia coli E24377A 5586333 YP_001464646.1 CDS nusA NC_009801.1 3653343 3654830 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(3653343..3654830) Escherichia coli E24377A 5590606 YP_001464647.1 CDS EcE24377A_3655 NC_009801.1 3654858 3655310 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(3654858..3655310) Escherichia coli E24377A 5590707 YP_001464648.1 CDS argG NC_009801.1 3655941 3657284 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3655941..3657284 Escherichia coli E24377A 5590278 YP_001464649.1 CDS yhbX NC_009801.1 3657292 3658917 R identified by match to protein family HMM PF00884; hypothetical protein complement(3657292..3658917) Escherichia coli E24377A 5586228 YP_001464650.1 CDS secG NC_009801.1 3659477 3659809 R identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810; preprotein translocase subunit SecG complement(3659477..3659809) Escherichia coli E24377A 5588607 YP_001464651.1 CDS glmM NC_009801.1 3660037 3661374 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(3660037..3661374) Escherichia coli E24377A 5586733 YP_001464652.1 CDS folP NC_009801.1 3661367 3662215 R catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase complement(3661367..3662215) Escherichia coli E24377A 5587565 YP_001464653.1 CDS hflB NC_009801.1 3662305 3664248 R inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease complement(3662305..3664248) Escherichia coli E24377A 5589725 YP_001464654.1 CDS rrmJ NC_009801.1 3664339 3664968 R Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase complement(3664339..3664968) Escherichia coli E24377A 5589226 YP_001464655.1 CDS EcE24377A_3665 NC_009801.1 3665094 3665387 D RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3665094..3665387 Escherichia coli E24377A 5590600 YP_001464656.1 CDS greA NC_009801.1 3665543 3666019 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(3665543..3666019) Escherichia coli E24377A 5588115 YP_001464657.1 CDS dacB NC_009801.1 3666267 3667700 D penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 3666267..3667700 Escherichia coli E24377A 5586556 YP_001464658.1 CDS obgE NC_009801.1 3667740 3668912 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(3667740..3668912) Escherichia coli E24377A 5590574 YP_001464659.1 CDS EcE24377A_3669 NC_009801.1 3668928 3669893 R identified by match to protein family HMM PF00892; transporter complement(3668928..3669893) Escherichia coli E24377A 5590758 YP_001464660.1 CDS rpmA NC_009801.1 3670020 3670277 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(3670020..3670277) Escherichia coli E24377A 5587906 YP_001464661.1 CDS EcE24377A_3672 NC_009801.1 3670271 3670816 D identified by similarity to GB:AAN82384.1; hypothetical protein 3670271..3670816 Escherichia coli E24377A 5589273 YP_001464662.1 CDS rplU NC_009801.1 3670298 3670609 R identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 complement(3670298..3670609) Escherichia coli E24377A 5586132 YP_001464663.1 CDS ispB NC_009801.1 3670868 3671839 D identified by similarity to SP:P0AD57; match to protein family HMM PF00348; octaprenyl diphosphate synthase 3670868..3671839 Escherichia coli E24377A 5587870 YP_001464664.1 CDS sfsB NC_009801.1 3672066 3672344 D activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3672066..3672344 Escherichia coli E24377A 5588177 YP_001464665.1 CDS murA NC_009801.1 3672392 3673651 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(3672392..3673651) Escherichia coli E24377A 5588590 YP_001464666.1 CDS EcE24377A_3676 NC_009801.1 3673706 3673975 R identified by match to protein family HMM PF01722; BolA/YrbA family protein complement(3673706..3673975) Escherichia coli E24377A 5586770 YP_001464667.1 CDS EcE24377A_3677 NC_009801.1 3673772 3674113 D identified by similarity to GB:AAN82389.1; hypothetical protein 3673772..3674113 Escherichia coli E24377A 5587869 YP_001464668.1 CDS yrbB NC_009801.1 3674120 3674413 R hypothetical protein complement(3674120..3674413) Escherichia coli E24377A 5589135 YP_001464669.1 CDS EcE24377A_3680 NC_009801.1 3674401 3675036 D identified by similarity to GB:AAN82391.1; hypothetical protein 3674401..3675036 Escherichia coli E24377A 5587963 YP_001464670.1 CDS ttg2D NC_009801.1 3674413 3675048 R identified by match to protein family HMM PF05494; toluene tolerance protein Ttg2D complement(3674413..3675048) Escherichia coli E24377A 5587107 YP_001464671.1 CDS EcE24377A_3681 NC_009801.1 3675067 3675618 R identified by match to protein family HMM PF02470; Mce family protein complement(3675067..3675618) Escherichia coli E24377A 5588580 YP_001464672.1 CDS EcE24377A_3682 NC_009801.1 3675623 3676405 R identified by match to protein family HMM PF02405; match to protein family HMM TIGR00056; toluene ABC transporter permease complement(3675623..3676405) Escherichia coli E24377A 5587413 YP_001464673.1 CDS EcE24377A_3683 NC_009801.1 3676413 3677222 R ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein complement(3676413..3677222) Escherichia coli E24377A 5590335 YP_001464674.1 CDS EcE24377A_3684 NC_009801.1 3677432 3678409 D YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 3677432..3678409 Escherichia coli E24377A 5588179 YP_001464675.1 CDS kdsD NC_009801.1 3678423 3679409 D identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; D-arabinose 5-phosphate isomerase 3678423..3679409 Escherichia coli E24377A 5587199 YP_001464676.1 CDS kdsC NC_009801.1 3679430 3679996 D forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3679430..3679996 Escherichia coli E24377A 5590532 YP_001464677.1 CDS EcE24377A_3687 NC_009801.1 3679993 3680568 D identified by match to protein family HMM PF06835; hypothetical protein 3679993..3680568 Escherichia coli E24377A 5590079 YP_001464678.1 CDS lptA NC_009801.1 3680537 3681094 D LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3680537..3681094 Escherichia coli E24377A 5590741 YP_001464679.1 CDS lptB NC_009801.1 3681101 3681826 D identified by similarity to SP:P0A9V1; match to protein family HMM PF00005; ABC transporter ATP-binding protein 3681101..3681826 Escherichia coli E24377A 5590197 YP_001464680.1 CDS rpoN NC_009801.1 3681874 3683307 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3681874..3683307 Escherichia coli E24377A 5588468 YP_001464681.1 CDS yfiA NC_009801.1 3683330 3683617 D YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 3683330..3683617 Escherichia coli E24377A 5586865 YP_001464682.1 CDS ptsN NC_009801.1 3683735 3684226 D identified by similarity to SP:P69829; match to protein family HMM PF00359; match to protein family HMM TIGR01419; PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3683735..3684226 Escherichia coli E24377A 5587763 YP_001464683.1 CDS EcE24377A_3693 NC_009801.1 3684272 3685126 D identified by match to protein family HMM PF03668; hypothetical protein 3684272..3685126 Escherichia coli E24377A 5587374 YP_001464684.1 CDS ptsO NC_009801.1 3685123 3685395 D identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003; phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3685123..3685395 Escherichia coli E24377A 5587420 YP_001464685.1 CDS EcE24377A_3696 NC_009801.1 3685609 3686241 D identified by similarity to SP:P64611; hypothetical protein 3685609..3686241 Escherichia coli E24377A 5586686 YP_001464686.1 CDS mtgA NC_009801.1 3686238 3686966 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(3686238..3686966) Escherichia coli E24377A 5588817 YP_001464687.1 CDS elbB NC_009801.1 3686963 3687616 R identified by similarity to SP:P0ABU5; match to protein family HMM PF01965; isoprenoid biosynthesis protein with amidotransferase-like domain complement(3686963..3687616) Escherichia coli E24377A 5590720 YP_001464688.1 CDS arcB NC_009801.1 3687846 3690182 R sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB complement(3687846..3690182) Escherichia coli E24377A 5588205 YP_001464689.1 CDS EcE24377A_3699 NC_009801.1 3690278 3691207 R identified by match to protein family HMM PF04055; match to protein family HMM TIGR01212; radical SAM family protein complement(3690278..3691207) Escherichia coli E24377A 5588492 YP_001464690.1 CDS gltB NC_009801.1 3691882 3696342 D catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3691882..3696342 Escherichia coli E24377A 5589389 YP_001464691.1 CDS gltD NC_009801.1 3696355 3697773 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3696355..3697773 Escherichia coli E24377A 5586735 YP_001464692.1 CDS EcE24377A_3702 NC_009801.1 3697957 3699084 D identified by similarity to GB:ABB63386.1; match to protein family HMM PF06250; hypothetical protein 3697957..3699084 Escherichia coli E24377A 5590533 YP_001464693.1 CDS EcE24377A_3703 NC_009801.1 3699144 3699608 R identified by similarity to SP:P0AF97; match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein complement(3699144..3699608) Escherichia coli E24377A 5587468 YP_001464694.1 CDS EcE24377A_3704 NC_009801.1 3699605 3700480 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(3699605..3700480) Escherichia coli E24377A 5589266 YP_001464695.1 CDS EcE24377A_3705 NC_009801.1 3700477 3701166 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(3700477..3701166) Escherichia coli E24377A 5585959 YP_001464696.1 CDS nanT1 NC_009801.1 3701214 3702704 R identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00891; sialic acid transporter complement(3701214..3702704) Escherichia coli E24377A 5589112 YP_001464697.1 CDS nanA NC_009801.1 3702813 3703706 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(3702813..3703706) Escherichia coli E24377A 5588958 YP_001464698.1 CDS nanR NC_009801.1 3703828 3704610 R Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR complement(3703828..3704610) Escherichia coli E24377A 5586067 YP_001464699.1 CDS EcE24377A_3709 NC_009801.1 3704999 3706321 D YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic; cryptic C4-dicarboxylate transporter DcuD 3704999..3706321 Escherichia coli E24377A 5588536 YP_001464700.1 CDS EcE24377A_3711 NC_009801.1 3706296 3706430 D identified by glimmer; hypothetical protein 3706296..3706430 Escherichia coli E24377A 5587844 YP_001464701.1 CDS sspB NC_009801.1 3706364 3706861 R identified by match to protein family HMM PF04386; ClpXP protease specificity-enhancing factor complement(3706364..3706861) Escherichia coli E24377A 5587725 YP_001464702.1 CDS sspA NC_009801.1 3706867 3707505 R transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A complement(3706867..3707505) Escherichia coli E24377A 5586189 YP_001464703.1 CDS rpsI NC_009801.1 3707900 3708292 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(3707900..3708292) Escherichia coli E24377A 5590801 YP_001464704.1 CDS rplM NC_009801.1 3708308 3708736 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(3708308..3708736) Escherichia coli E24377A 5586677 YP_001464705.1 CDS EcE24377A_3715 NC_009801.1 3708955 3710082 R identified by match to protein family HMM PF03969; AFG1 family ATPase complement(3708955..3710082) Escherichia coli E24377A 5587302 YP_001464706.1 CDS EcE24377A_3716 NC_009801.1 3710276 3710674 D identified by match to protein family HMM PF06295; cytochrome d ubiquinol oxidase subunit III 3710276..3710674 Escherichia coli E24377A 5588944 YP_001464707.1 CDS degQ NC_009801.1 3710828 3712195 D identified by similarity to SP:P39099; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; serine endoprotease 3710828..3712195 Escherichia coli E24377A 5588791 YP_001464708.1 CDS degS NC_009801.1 3712285 3713352 D identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02038; serine endoprotease 3712285..3713352 Escherichia coli E24377A 5590786 YP_001464709.1 CDS mdh NC_009801.1 3713414 3714352 R oxidizes malate to oxaloacetate; malate dehydrogenase complement(3713414..3714352) Escherichia coli E24377A 5586293 YP_001464710.1 CDS argR NC_009801.1 3714787 3715257 D regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 3714787..3715257 Escherichia coli E24377A 5587916 YP_001464711.1 CDS ycfR NC_009801.1 3715622 3715885 D identified by similarity to SP:P0AB40; match to protein family HMM PF07338; protein YcfR 3715622..3715885 Escherichia coli E24377A 5588722 YP_001464712.1 CDS EcE24377A_3722 NC_009801.1 3715941 3716213 R identified by similarity to SP:P64616; hypothetical protein complement(3715941..3716213) Escherichia coli E24377A 5589284 YP_001464713.1 CDS aaeB NC_009801.1 3716305 3718272 R with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB complement(3716305..3718272) Escherichia coli E24377A 5590071 YP_001464714.1 CDS aaeA NC_009801.1 3718278 3719210 R with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA complement(3718278..3719210) Escherichia coli E24377A 5590696 YP_001464715.2 CDS aaeX NC_009801.1 3719218 3719421 R membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein complement(3719218..3719421) Escherichia coli E24377A 5590134 YP_001464716.1 CDS aaeR NC_009801.1 3719604 3720533 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator 3719604..3720533 Escherichia coli E24377A 5589083 YP_001464717.1 CDS tldD NC_009801.1 3720661 3722106 R responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD complement(3720661..3722106) Escherichia coli E24377A 5590416 YP_001464718.1 CDS EcE24377A_3728 NC_009801.1 3722262 3726062 R identified by match to protein family HMM TIGR02099; hypothetical protein complement(3722262..3726062) Escherichia coli E24377A 5586624 YP_001464719.1 CDS cafA NC_009801.1 3726130 3727599 R involved in the processing of the 5'end of 16S rRNA; ribonuclease G complement(3726130..3727599) Escherichia coli E24377A 5590130 YP_001464720.1 CDS maf1 NC_009801.1 3727589 3728182 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(3727589..3728182) Escherichia coli E24377A 5590485 YP_001464721.1 CDS lytS NC_009801.1 3728191 3728679 R part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD complement(3728191..3728679) Escherichia coli E24377A 5586082 YP_001464723.1 CDS mreC NC_009801.1 3728679 3729782 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(3728679..3729782) Escherichia coli E24377A 5588666 YP_001464724.1 CDS mreB NC_009801.1 3729848 3730891 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(3729848..3730891) Escherichia coli E24377A 5587386 YP_001464725.1 CDS EcE24377A_3735 NC_009801.1 3730999 3731187 D identified by similarity to GB:AAN82447.1; hypothetical protein 3730999..3731187 Escherichia coli E24377A 5590136 YP_001464726.1 CDS EcE24377A_3736 NC_009801.1 3731196 3733136 R regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD complement(3731196..3733136) Escherichia coli E24377A 5587363 YP_001464727.1 CDS EcE24377A_3737 NC_009801.1 3733288 3734262 D identified by similarity to PDB:1O8C_A; match to protein family HMM PF00107; match to protein family HMM PF01262; match to protein family HMM PF08240; match to protein family HMM TIGR02823; quinone oxidoreductase 3733288..3734262 Escherichia coli E24377A 5586257 YP_001464728.1 CDS accB NC_009801.1 3735240 3735710 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3735240..3735710 Escherichia coli E24377A 5589829 YP_001464729.1 CDS accC NC_009801.1 3735721 3737070 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3735721..3737070 Escherichia coli E24377A 5589131 YP_001464730.1 CDS EcE24377A_3741 NC_009801.1 3737179 3737421 D identified by match to protein family HMM PF06196; hypothetical protein 3737179..3737421 Escherichia coli E24377A 5589510 YP_001464731.1 CDS panF NC_009801.1 3737411 3738862 D mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3737411..3738862 Escherichia coli E24377A 5588422 YP_001464732.1 CDS prmA NC_009801.1 3738874 3739755 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 3738874..3739755 Escherichia coli E24377A 5589299 YP_001464733.1 CDS EcE24377A_3744 NC_009801.1 3739820 3739912 D identified by glimmer; hypothetical protein 3739820..3739912 Escherichia coli E24377A 5588412 YP_001464734.1 CDS dusB NC_009801.1 3740084 3741049 D identified by similarity to SP:P0ABT5; match to protein family HMM PF01207; match to protein family HMM TIGR00737; tRNA-dihydrouridine synthase B 3740084..3741049 Escherichia coli E24377A 5587941 YP_001464735.1 CDS fis NC_009801.1 3741075 3741371 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3741075..3741371 Escherichia coli E24377A 5589740 YP_001464736.1 CDS EcE24377A_3747 NC_009801.1 3741457 3742341 D identified by match to protein family HMM PF01555; methyltransferase 3741457..3742341 Escherichia coli E24377A 5590137 YP_001464737.1 CDS EcE24377A_3748 NC_009801.1 3742398 3742604 D identified by similarity to GB:AAN82469.1; hypothetical protein 3742398..3742604 Escherichia coli E24377A 5589646 YP_001464738.1 CDS EcE24377A_3749 NC_009801.1 3742607 3743269 R identified by similarity to SP:P0ACT2; match to protein family HMM PF00440; match to protein family HMM PF08361; DNA-binding transcriptional regulator EnvR complement(3742607..3743269) Escherichia coli E24377A 5587618 YP_001464739.1 CDS acrE NC_009801.1 3743668 3744825 D identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; acriflavine resistance protein E 3743668..3744825 Escherichia coli E24377A 5587573 YP_001464740.1 CDS acrF NC_009801.1 3744837 3747941 D identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; acriflavine resistance protein F 3744837..3747941 Escherichia coli E24377A 5588989 YP_001464741.1 CDS EcE24377A_3752 NC_009801.1 3748194 3748415 D lipoprotein 3748194..3748415 Escherichia coli E24377A 5587130 YP_001464742.1 CDS EcE24377A_3753 NC_009801.1 3748641 3748817 D hypothetical protein 3748641..3748817 Escherichia coli E24377A 5588620 YP_001464743.1 CDS EcE24377A_3754 NC_009801.1 3748846 3749871 D amino acid ABC transporter substrate-binding protein 3748846..3749871 Escherichia coli E24377A 5590153 YP_001464744.1 CDS EcE24377A_3755 NC_009801.1 3749939 3751120 D identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; His/Glu/Gln/Arg/opine ABC transporter permease 3749939..3751120 Escherichia coli E24377A 5588381 YP_001464745.1 CDS EcE24377A_3756 NC_009801.1 3751130 3752233 D identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; His/Glu/Gln/Arg/opine ABC transporter permease 3751130..3752233 Escherichia coli E24377A 5587123 YP_001464746.1 CDS EcE24377A_3757 NC_009801.1 3752241 3752999 D yhdZ; identified by match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 3752241..3752999 Escherichia coli E24377A 5586523 YP_001464747.1 CDS EcE24377A_3763 NC_009801.1 3758722 3759603 D hypothetical protein 3758722..3759603 Escherichia coli E24377A 5586203 YP_001464748.1 CDS EcE24377A_3762 NC_009801.1 3759579 3759836 R identified by similarity to SP:P45795; match to protein family HMM PF07369; hypothetical protein complement(3759579..3759836) Escherichia coli E24377A 5587120 YP_001464749.1 CDS aroE NC_009801.1 3759833 3760651 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(3759833..3760651) Escherichia coli E24377A 5588912 YP_001464750.1 CDS EcE24377A_3765 NC_009801.1 3760656 3761273 R RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor complement(3760656..3761273) Escherichia coli E24377A 5586472 YP_001464751.1 CDS EcE24377A_3766 NC_009801.1 3761233 3761775 R identified by match to protein family HMM PF01396; topoisomerase DNA-binding C4 zinc finger domain-containing protein complement(3761233..3761775) Escherichia coli E24377A 5590612 YP_001464752.1 CDS smg NC_009801.1 3761804 3762277 R identified by similarity to SP:P66822; match to protein family HMM PF04361; hypothetical protein complement(3761804..3762277) Escherichia coli E24377A 5590032 YP_001464753.1 CDS dprA NC_009801.1 3762249 3763373 R identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732; DNA protecting protein DprA complement(3762249..3763373) Escherichia coli E24377A 5589820 YP_001464754.1 CDS def NC_009801.1 3763503 3764012 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3763503..3764012 Escherichia coli E24377A 5586685 YP_001464755.1 CDS fmt NC_009801.1 3764027 3764974 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3764027..3764974 Escherichia coli E24377A 5587402 YP_001464756.1 CDS rsmB NC_009801.1 3765020 3766309 D catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase GidB 3765020..3766309 Escherichia coli E24377A 5587411 YP_001464757.1 CDS trkA NC_009801.1 3766331 3767707 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 3766331..3767707 Escherichia coli E24377A 5589802 YP_001464758.1 CDS mscL NC_009801.1 3767837 3768247 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3767837..3768247 Escherichia coli E24377A 5586513 YP_001464759.1 CDS EcE24377A_3773 NC_009801.1 3768244 3768462 R identified by match to protein family HMM PF03889; hypothetical protein complement(3768244..3768462) Escherichia coli E24377A 5589160 YP_001464760.1 CDS zntR NC_009801.1 3768518 3768943 R mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator complement(3768518..3768943) Escherichia coli E24377A 5589388 YP_001464761.1 CDS EcE24377A_3776 NC_009801.1 3768954 3769322 R identified by similarity to SP:P36677; hypothetical protein complement(3768954..3769322) Escherichia coli E24377A 5590364 YP_001464762.1 CDS rplQ NC_009801.1 3769429 3769812 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(3769429..3769812) Escherichia coli E24377A 5587888 YP_001464763.1 CDS rpoA NC_009801.1 3769853 3770842 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(3769853..3770842) Escherichia coli E24377A 5586179 YP_001464764.1 CDS rpsD NC_009801.1 3770868 3771488 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(3770868..3771488) Escherichia coli E24377A 5590248 YP_001464765.1 CDS rpsK NC_009801.1 3771522 3771911 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(3771522..3771911) Escherichia coli E24377A 5588562 YP_001464766.1 CDS rpsM NC_009801.1 3771928 3772284 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(3771928..3772284) Escherichia coli E24377A 5586542 YP_001464767.1 CDS rpmJ NC_009801.1 3772431 3772547 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(3772431..3772547) Escherichia coli E24377A 5588641 YP_001464768.1 CDS secY NC_009801.1 3772579 3773910 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(3772579..3773910) Escherichia coli E24377A 5589888 YP_001464769.1 CDS rplO NC_009801.1 3773918 3774352 R late assembly protein; 50S ribosomal protein L15 complement(3773918..3774352) Escherichia coli E24377A 5586352 YP_001464770.1 CDS rpmD NC_009801.1 3774356 3774535 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(3774356..3774535) Escherichia coli E24377A 5587641 YP_001464771.1 CDS rpsE NC_009801.1 3774539 3775042 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(3774539..3775042) Escherichia coli E24377A 5588065 YP_001464772.1 CDS rplR NC_009801.1 3775057 3775410 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(3775057..3775410) Escherichia coli E24377A 5587030 YP_001464773.1 CDS rplF NC_009801.1 3775420 3775953 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(3775420..3775953) Escherichia coli E24377A 5587035 YP_001464774.1 CDS rpsH NC_009801.1 3775966 3776358 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(3775966..3776358) Escherichia coli E24377A 5588720 YP_001464775.1 CDS rpsN NC_009801.1 3776392 3776697 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(3776392..3776697) Escherichia coli E24377A 5587112 YP_001464776.1 CDS rplE NC_009801.1 3776712 3777251 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(3776712..3777251) Escherichia coli E24377A 5586898 YP_001464777.1 CDS rplX NC_009801.1 3777266 3777580 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(3777266..3777580) Escherichia coli E24377A 5590171 YP_001464778.1 CDS rplN NC_009801.1 3777591 3777962 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(3777591..3777962) Escherichia coli E24377A 5586812 YP_001464779.1 CDS rpsQ NC_009801.1 3778127 3778381 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(3778127..3778381) Escherichia coli E24377A 5589511 YP_001464780.1 CDS rpmC NC_009801.1 3778381 3778572 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(3778381..3778572) Escherichia coli E24377A 5590221 YP_001464781.1 CDS rplP NC_009801.1 3778572 3778982 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(3778572..3778982) Escherichia coli E24377A 5588276 YP_001464782.1 CDS rpsC NC_009801.1 3778995 3779696 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(3778995..3779696) Escherichia coli E24377A 5589386 YP_001464783.1 CDS rplV NC_009801.1 3779714 3780046 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(3779714..3780046) Escherichia coli E24377A 5586986 YP_001464784.1 CDS rpsS NC_009801.1 3780061 3780339 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(3780061..3780339) Escherichia coli E24377A 5585936 YP_001464785.1 CDS rplB NC_009801.1 3780356 3781177 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(3780356..3781177) Escherichia coli E24377A 5589908 YP_001464786.1 CDS rplW NC_009801.1 3781195 3781497 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(3781195..3781497) Escherichia coli E24377A 5589037 YP_001464787.1 CDS rplD NC_009801.1 3781494 3782099 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(3781494..3782099) Escherichia coli E24377A 5588810 YP_001464788.1 CDS rplC NC_009801.1 3782110 3782739 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(3782110..3782739) Escherichia coli E24377A 5590558 YP_001464789.1 CDS rpsJ NC_009801.1 3782772 3783083 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(3782772..3783083) Escherichia coli E24377A 5586557 YP_001464790.1 CDS EcE24377A_3806 NC_009801.1 3783462 3783929 D identified by match to protein family HMM PF01478; A24 family peptidase 3783462..3783929 Escherichia coli E24377A 5587464 YP_001464791.1 CDS bfr NC_009801.1 3783926 3784402 R iron storage protein; bacterioferritin complement(3783926..3784402) Escherichia coli E24377A 5588378 YP_001464792.1 CDS bfd NC_009801.1 3784475 3784669 R identified by similarity to SP:P0AE56; match to protein family HMM PF04324; bacterioferritin-associated ferredoxin complement(3784475..3784669) Escherichia coli E24377A 5586464 YP_001464793.1 CDS tuf1 NC_009801.1 3784852 3786036 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(3784852..3786036) Escherichia coli E24377A 5587408 YP_001464794.1 CDS fusA NC_009801.1 3786107 3788221 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(3786107..3788221) Escherichia coli E24377A 5589684 YP_001464795.1 CDS rpsG NC_009801.1 3788318 3788788 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(3788318..3788788) Escherichia coli E24377A 5588799 YP_001464796.1 CDS rpsL NC_009801.1 3788885 3789259 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(3788885..3789259) Escherichia coli E24377A 5590808 YP_001464797.1 CDS dsrH NC_009801.1 3789385 3789672 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB complement(3789385..3789672) Escherichia coli E24377A 5586512 YP_001464798.1 CDS tusC NC_009801.1 3789680 3790039 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC complement(3789680..3790039) Escherichia coli E24377A 5590744 YP_001464799.1 CDS tusD NC_009801.1 3790039 3790425 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD complement(3790039..3790425) Escherichia coli E24377A 5588199 YP_001464800.1 CDS EcE24377A_3815 NC_009801.1 3790425 3791147 R identified by match to protein family HMM PF08348; hypothetical protein complement(3790425..3791147) Escherichia coli E24377A 5588003 YP_001464801.1 CDS fkpA NC_009801.1 3791314 3792126 R rotamase; FKBP-type peptidylprolyl isomerase complement(3791314..3792126) Escherichia coli E24377A 5589120 YP_001464802.1 CDS EcE24377A_3817 NC_009801.1 3792347 3792565 D identified by match to protein family HMM PF04102; hypothetical protein 3792347..3792565 Escherichia coli E24377A 5585990 YP_001464803.1 CDS slyD NC_009801.1 3792614 3793204 R rotamase; FKBP-type peptidylprolyl isomerase complement(3792614..3793204) Escherichia coli E24377A 5586703 YP_001464804.1 CDS EcE24377A_3819 NC_009801.1 3793299 3793499 R identified by similarity to SP:P0ADW8; match to protein family HMM TIGR02443; hypothetical protein complement(3793299..3793499) Escherichia coli E24377A 5588221 YP_001464805.1 CDS kefB NC_009801.1 3793509 3795314 R involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB complement(3793509..3795314) Escherichia coli E24377A 5589033 YP_001464806.1 CDS kefG NC_009801.1 3795314 3795868 R required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG complement(3795314..3795868) Escherichia coli E24377A 5588769 YP_001464807.1 CDS EcE24377A_3822 NC_009801.1 3795996 3797909 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3795996..3797909 Escherichia coli E24377A 5587037 YP_001464808.1 CDS EcE24377A_3823 NC_009801.1 3797909 3798931 D identified by match to protein family HMM PF00561; hydrolase 3797909..3798931 Escherichia coli E24377A 5586422 YP_001464809.1 CDS EcE24377A_3824 NC_009801.1 3798925 3799143 D identified by match to protein family HMM PF06794; hypothetical protein 3798925..3799143 Escherichia coli E24377A 5590403 YP_001464810.1 CDS EcE24377A_3825 NC_009801.1 3799197 3800066 D identified by match to protein family HMM PF00485; phosphoribulokinase/uridine kinase 3799197..3800066 Escherichia coli E24377A 5589118 YP_001464811.1 CDS EcE24377A_3826 NC_009801.1 3800121 3800525 R identified by match to protein family HMM PF02566; hypothetical protein complement(3800121..3800525) Escherichia coli E24377A 5586669 YP_001464812.1 CDS crp NC_009801.1 3800827 3801459 D complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3800827..3801459 Escherichia coli E24377A 5589337 YP_001464813.1 CDS EcE24377A_3828 NC_009801.1 3801510 3803600 D identified by match to protein family HMM PF05976; match to protein family HMM TIGR01667; hypothetical protein 3801510..3803600 Escherichia coli E24377A 5588493 YP_001464814.1 CDS argD NC_009801.1 3803667 3804887 R DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase complement(3803667..3804887) Escherichia coli E24377A 5587568 YP_001464815.1 CDS pabA NC_009801.1 3804973 3805536 R aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II complement(3804973..3805536) Escherichia coli E24377A 5590828 YP_001464816.1 CDS fic NC_009801.1 3805568 3806170 R identified by similarity to SP:P20605; match to protein family HMM PF02661; cell filamentation protein Fic complement(3805568..3806170) Escherichia coli E24377A 5589787 YP_001464817.1 CDS ppiA NC_009801.1 3806432 3807004 R identified by similarity to SP:P20752; match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase A complement(3806432..3807004) Escherichia coli E24377A 5586975 YP_001464818.1 CDS tsgA NC_009801.1 3807275 3808456 D identified by match to protein family HMM PF07690; hypothetical protein 3807275..3808456 Escherichia coli E24377A 5588664 YP_001464819.1 CDS EcE24377A_3834 NC_009801.1 3808589 3808765 R identified by similarity to GB:AAX67313.1; hypothetical protein complement(3808589..3808765) Escherichia coli E24377A 5588426 YP_001464820.1 CDS nirB NC_009801.1 3808718 3811261 D identified by match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374; nitrite reductase [NAD(P)H], large subunit 3808718..3811261 Escherichia coli E24377A 5586083 YP_001464821.1 CDS nirD NC_009801.1 3811258 3811584 D involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3811258..3811584 Escherichia coli E24377A 5586973 YP_001464822.1 CDS nirC NC_009801.1 3811711 3812517 D member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3811711..3812517 Escherichia coli E24377A 5586784 YP_001464823.1 CDS cysG NC_009801.1 3812536 3813909 D multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3812536..3813909 Escherichia coli E24377A 5585910 YP_001464824.1 CDS EcE24377A_3839 NC_009801.1 3814156 3814323 D lipoprotein 3814156..3814323 Escherichia coli E24377A 5589524 YP_001464825.1 CDS frlA NC_009801.1 3814567 3815955 D inner membrane protein possibly involved in fructoselysine transport; member of the flr operon; fructoselysine transporter 3814567..3815955 Escherichia coli E24377A 5590330 YP_001464826.1 CDS frlB NC_009801.1 3815955 3816998 D catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine; fructoselysine-6-P-deglycase 3815955..3816998 Escherichia coli E24377A 5586654 YP_001464827.1 CDS EcE24377A_3842 NC_009801.1 3817048 3817878 D YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine; fructoselysine 3-epimerase 3817048..3817878 Escherichia coli E24377A 5590804 YP_001464828.1 CDS EcE24377A_3843 NC_009801.1 3817875 3818660 D identified by match to protein family HMM PF00294; fructoselysine 6-kinase 3817875..3818660 Escherichia coli E24377A 5586845 YP_001464829.1 CDS frlR NC_009801.1 3818760 3819491 D may act as a transcriptional regulator of a fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes; DNA-binding transcriptional regulator FrlR 3818760..3819491 Escherichia coli E24377A 5588332 YP_001464830.1 CDS EcE24377A_3845 NC_009801.1 3819643 3820728 R identified by similarity to GB:ABB67851.1; hypothetical protein complement(3819643..3820728) Escherichia coli E24377A 5587046 YP_001464831.1 CDS EcE24377A_3846 NC_009801.1 3820740 3822044 R identified by similarity to SP:P45546; hypothetical protein complement(3820740..3822044) Escherichia coli E24377A 5587733 YP_001464832.1 CDS EcE24377A_3847 NC_009801.1 3822056 3822409 R hypothetical protein complement(3822056..3822409) Escherichia coli E24377A 5588257 YP_001464833.1 CDS EcE24377A_3848 NC_009801.1 3822420 3823298 R phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); hydrolase complement(3822420..3823298) Escherichia coli E24377A 5590778 YP_001464834.1 CDS EcE24377A_3849 NC_009801.1 3823295 3824521 R identified by match to protein family HMM PF01676; match to protein family HMM PF08342; mutase complement(3823295..3824521) Escherichia coli E24377A 5588946 YP_001464835.1 CDS EcE24377A_3850 NC_009801.1 3824521 3825684 R identified by match to protein family HMM PF01168; alanine racemase complement(3824521..3825684) Escherichia coli E24377A 5587330 YP_001464836.1 CDS EcE24377A_3851 NC_009801.1 3825768 3826130 R hypothetical protein complement(3825768..3826130) Escherichia coli E24377A 5590182 YP_001464837.1 CDS EcE24377A_3852 NC_009801.1 3826147 3827052 R identified by similarity to OMNI:NTL01SF3196; hypothetical protein complement(3826147..3827052) Escherichia coli E24377A 5590501 YP_001464838.1 CDS trpS NC_009801.1 3827321 3828325 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(3827321..3828325) Escherichia coli E24377A 5587583 YP_001464839.1 CDS gph NC_009801.1 3828318 3829076 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(3828318..3829076) Escherichia coli E24377A 5588271 YP_001464840.1 CDS rpe NC_009801.1 3829069 3829746 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(3829069..3829746) Escherichia coli E24377A 5589154 YP_001464841.1 CDS dam NC_009801.1 3829764 3830600 R identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571; DNA adenine methylase complement(3829764..3830600) Escherichia coli E24377A 5589490 YP_001464842.1 CDS damX NC_009801.1 3830707 3831984 R identified by similarity to SP:P11557; match to protein family HMM PF05036; hypothetical protein complement(3830707..3831984) Escherichia coli E24377A 5590549 YP_001464843.1 CDS aroB NC_009801.1 3832076 3833164 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(3832076..3833164) Escherichia coli E24377A 5587826 YP_001464844.1 CDS aroK NC_009801.1 3833221 3833742 R type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I complement(3833221..3833742) Escherichia coli E24377A 5589731 YP_001464845.1 CDS hofQ NC_009801.1 3834143 3835381 R outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ complement(3834143..3835381) Escherichia coli E24377A 5588048 YP_001464846.1 CDS EcE24377A_3862 NC_009801.1 3835293 3835697 R hypothetical protein complement(3835293..3835697) Escherichia coli E24377A 5586656 YP_001464847.1 CDS EcE24377A_3863 NC_009801.1 3835687 3836127 R hypothetical protein complement(3835687..3836127) Escherichia coli E24377A 5585988 YP_001464848.1 CDS EcE24377A_3865 NC_009801.1 3836111 3836650 R identified by match to protein family HMM PF05137; PilN family protein complement(3836111..3836650) Escherichia coli E24377A 5587594 YP_001464849.1 CDS hofM NC_009801.1 3836650 3837429 R identified by similarity to SP:P45753; HofM protein complement(3836650..3837429) Escherichia coli E24377A 5586497 YP_001464850.1 CDS mrcA NC_009801.1 3837549 3840101 D bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3837549..3840101 Escherichia coli E24377A 5588273 YP_001464851.1 CDS nudE NC_009801.1 3840266 3840826 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE complement(3840266..3840826) Escherichia coli E24377A 5585950 YP_001464852.1 CDS EcE24377A_3869 NC_009801.1 3841030 3841149 D identified by glimmer; hypothetical protein 3841030..3841149 Escherichia coli E24377A 5588494 YP_001464853.1 CDS EcE24377A_3870 NC_009801.1 3841146 3843281 D identified by similarity to SP:P45800; match to protein family HMM PF07095; hypothetical protein 3841146..3843281 Escherichia coli E24377A 5589094 YP_001464854.1 CDS EcE24377A_3871 NC_009801.1 3843346 3844014 D identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; HAD family hydrolase 3843346..3844014 Escherichia coli E24377A 5590086 YP_001464855.1 CDS hslR NC_009801.1 3844025 3844426 D identified by similarity to SP:P0ACG8; match to protein family HMM PF01479; ribosome-associated heat shock protein Hsp15 3844025..3844426 Escherichia coli E24377A 5586689 YP_001464856.1 CDS hslO NC_009801.1 3844445 3845329 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3844445..3845329 Escherichia coli E24377A 5588030 YP_001464857.1 CDS EcE24377A_3874 NC_009801.1 3845464 3847188 R identified by similarity to SP:P45804; hypothetical protein complement(3845464..3847188) Escherichia coli E24377A 5588579 YP_001464858.1 CDS EcE24377A_3875 NC_009801.1 3847194 3847313 R identified by glimmer; hypothetical protein complement(3847194..3847313) Escherichia coli E24377A 5590478 YP_001464859.1 CDS EcE24377A_3876 NC_009801.1 3847264 3847395 R identified by similarity to GB:AAN44882.1; hypothetical protein complement(3847264..3847395) Escherichia coli E24377A 5589765 YP_001464860.1 CDS pckA NC_009801.1 3847567 3849189 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3847567..3849189 Escherichia coli E24377A 5587501 YP_001464861.1 CDS envZ NC_009801.1 3849265 3850617 R membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein complement(3849265..3850617) Escherichia coli E24377A 5587293 YP_001464862.1 CDS ompR NC_009801.1 3850614 3851333 R part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator complement(3850614..3851333) Escherichia coli E24377A 5589840 YP_001464863.1 CDS greB NC_009801.1 3851561 3852037 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3851561..3852037 Escherichia coli E24377A 5586743 YP_001464864.1 CDS yhgF NC_009801.1 3852134 3854455 D identified by match to protein family HMM PF00575; protein yhgF 3852134..3854455 Escherichia coli E24377A 5589564 YP_001464865.1 CDS EcE24377A_3882 NC_009801.1 3854490 3854582 D identified by glimmer; hypothetical protein 3854490..3854582 Escherichia coli E24377A 5590253 YP_001464866.1 CDS feoA NC_009801.1 3854893 3855120 D identified by match to protein family HMM PF04023; ferrous iron transport protein A 3854893..3855120 Escherichia coli E24377A 5588771 YP_001464867.1 CDS feoB NC_009801.1 3855137 3857458 D cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3855137..3857458 Escherichia coli E24377A 5589177 YP_001464868.1 CDS EcE24377A_3885 NC_009801.1 3857458 3857694 D identified by match to protein family HMM PF09012; hypothetical protein 3857458..3857694 Escherichia coli E24377A 5589420 YP_001464869.1 CDS EcE24377A_3886 NC_009801.1 3857897 3858775 D identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein 3857897..3858775 Escherichia coli E24377A 5590131 YP_001464870.1 CDS EcE24377A_3887 NC_009801.1 3858804 3859574 R Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH complement(3858804..3859574) Escherichia coli E24377A 5589919 YP_001464871.1 CDS gntX NC_009801.1 3859612 3860295 D involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3859612..3860295 Escherichia coli E24377A 5588339 YP_001464872.1 CDS gntY NC_009801.1 3860354 3860929 D cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 3860354..3860929 Escherichia coli E24377A 5586776 YP_001464873.1 CDS EcE24377A_3890 NC_009801.1 3861182 3861274 D identified by glimmer; hypothetical protein 3861182..3861274 Escherichia coli E24377A 5590193 YP_001464874.1 CDS gntT NC_009801.1 3861290 3862606 D identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791; high-affinity gluconate transporter 3861290..3862606 Escherichia coli E24377A 5586214 YP_001464875.1 CDS malQ NC_009801.1 3862651 3864735 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(3862651..3864735) Escherichia coli E24377A 5590604 YP_001464876.1 CDS malP NC_009801.1 3864745 3867138 R identified by similarity to SP:P00490; match to protein family HMM PF00343; match to protein family HMM TIGR02093; maltodextrin phosphorylase complement(3864745..3867138) Escherichia coli E24377A 5589848 YP_001464877.1 CDS malT NC_009801.1 3867750 3870455 D Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3867750..3870455 Escherichia coli E24377A 5587299 YP_001464878.1 CDS rtcA NC_009801.1 3870498 3871514 R catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase complement(3870498..3871514) Escherichia coli E24377A 5586091 YP_001464879.1 CDS EcE24377A_3897 NC_009801.1 3871062 3872183 D identified by glimmer; hypothetical protein 3871062..3872183 Escherichia coli E24377A 5590845 YP_001464880.1 CDS rtcB NC_009801.1 3871518 3872744 R identified by similarity to SP:P46850; match to protein family HMM PF01139; RtcB protein complement(3871518..3872744) Escherichia coli E24377A 5586859 YP_001464881.1 CDS rtcR NC_009801.1 3872933 3874531 D identified by similarity to SP:P38035; match to protein family HMM PF00158; match to protein family HMM PF06956; match to protein family HMM PF07728; sigma-54 dependent transcriptional regulator RtcR 3872933..3874531 Escherichia coli E24377A 5586881 YP_001464882.1 CDS glpR NC_009801.1 3874513 3875271 R represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR complement(3874513..3875271) Escherichia coli E24377A 5588008 YP_001464883.1 CDS EcE24377A_3900 NC_009801.1 3875288 3876118 R protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG complement(3875288..3876118) Escherichia coli E24377A 5590448 YP_001464884.1 CDS glpE NC_009801.1 3876163 3876489 R belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase complement(3876163..3876489) Escherichia coli E24377A 5587125 YP_001464885.1 CDS glpD NC_009801.1 3876679 3878184 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3876679..3878184 Escherichia coli E24377A 5589056 YP_001464886.1 CDS EcE24377A_3903 NC_009801.1 3878238 3878843 R identified by similarity to GB:AAN82642.1; hypothetical protein complement(3878238..3878843) Escherichia coli E24377A 5586026 YP_001464887.1 CDS EcE24377A_3904 NC_009801.1 3878846 3879613 R hypothetical protein complement(3878846..3879613) Escherichia coli E24377A 5586342 YP_001464888.1 CDS EcE24377A_3905 NC_009801.1 3879616 3880326 R hypothetical protein complement(3879616..3880326) Escherichia coli E24377A 5590341 YP_001464889.1 CDS EcE24377A_3906 NC_009801.1 3880341 3881846 R hypothetical protein complement(3880341..3881846) Escherichia coli E24377A 5586914 YP_001464890.1 CDS glgP NC_009801.1 3881974 3884421 R identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093; glycogen phosphorylase complement(3881974..3884421) Escherichia coli E24377A 5589345 YP_001464891.1 CDS glgA NC_009801.1 3884440 3885873 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(3884440..3885873) Escherichia coli E24377A 5588710 YP_001464892.1 CDS glgC NC_009801.1 3885873 3887168 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(3885873..3887168) Escherichia coli E24377A 5590526 YP_001464893.1 CDS glgX NC_009801.1 3887186 3889159 R catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein complement(3887186..3889159) Escherichia coli E24377A 5587748 YP_001464894.1 CDS glgB NC_009801.1 3889156 3891342 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein complement(3889156..3891342) Escherichia coli E24377A 5586828 YP_001464895.1 CDS asd NC_009801.1 3891615 3892718 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(3891615..3892718) Escherichia coli E24377A 5590793 YP_001464896.1 CDS EcE24377A_3913 NC_009801.1 3892911 3893504 D YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 3892911..3893504 Escherichia coli E24377A 5587269 YP_001464897.1 CDS gntU NC_009801.1 3893561 3894901 R identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791; low affinity gluconate transporter complement(3893561..3894901) Escherichia coli E24377A 5589949 YP_001464898.1 CDS gntK NC_009801.1 3894905 3895432 R thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase complement(3894905..3895432) Escherichia coli E24377A 5590484 YP_001464899.1 CDS gntR NC_009801.1 3895571 3896566 R identified by similarity to SP:P0ACP5; match to protein family HMM PF00356; match to protein family HMM PF00532; GntR family transcriptional regulator complement(3895571..3896566) Escherichia coli E24377A 5588478 YP_001464900.1 CDS EcE24377A_3917 NC_009801.1 3896790 3897485 R identified by match to protein family HMM PF02678; match to protein family HMM PF07883; pirin complement(3896790..3897485) Escherichia coli E24377A 5588212 YP_001464901.1 CDS EcE24377A_3918 NC_009801.1 3897608 3898645 R identified by match to protein family HMM PF01408; match to protein family HMM PF02894; dehydrogenase complement(3897608..3898645) Escherichia coli E24377A 5590372 YP_001464902.1 CDS EcE24377A_3919 NC_009801.1 3898556 3898744 D identified by glimmer; hypothetical protein 3898556..3898744 Escherichia coli E24377A 5589687 YP_001464903.1 CDS EcE24377A_3920 NC_009801.1 3898978 3899466 D YhhY; regulated by the fur regulator; unknown function; acetyltransferase YhhY 3898978..3899466 Escherichia coli E24377A 5587698 YP_001464904.1 CDS EcE24377A_3921 NC_009801.1 3899703 3900881 D identified by match to protein family HMM PF01844; match to protein family HMM PF05638; match to protein family HMM TIGR03344; HNH endonuclease domain-containing protein 3899703..3900881 Escherichia coli E24377A 5589133 YP_001464905.1 CDS EcE24377A_3922 NC_009801.1 3900878 3901372 D hypothetical protein 3900878..3901372 Escherichia coli E24377A 5588820 YP_001464906.1 CDS EcE24377A_3923 NC_009801.1 3901822 3902106 D identified by glimmer; hypothetical protein 3901822..3902106 Escherichia coli E24377A 5588481 YP_001464907.1 CDS ggt NC_009801.1 3902144 3903877 R periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase complement(3902144..3903877) Escherichia coli E24377A 5585953 YP_001464908.1 CDS EcE24377A_3925 NC_009801.1 3903843 3903965 D identified by glimmer; hypothetical protein 3903843..3903965 Escherichia coli E24377A 5589293 YP_001464909.1 CDS EcE24377A_3927 NC_009801.1 3903998 3904438 D hypothetical protein 3903998..3904438 Escherichia coli E24377A 5590201 YP_001464910.1 CDS ugpQ NC_009801.1 3904425 3905168 R hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase complement(3904425..3905168) Escherichia coli E24377A 5588361 YP_001464911.1 CDS ugpC NC_009801.1 3905165 3906235 R part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit complement(3905165..3906235) Escherichia coli E24377A 5587183 YP_001464912.1 CDS EcE24377A_3929 NC_009801.1 3906237 3907082 R with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein complement(3906237..3907082) Escherichia coli E24377A 5587639 YP_001464913.1 CDS ugpA NC_009801.1 3907079 3907966 R with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease complement(3907079..3907966) Escherichia coli E24377A 5590159 YP_001464914.1 CDS ugpB NC_009801.1 3908064 3909380 R with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein complement(3908064..3909380) Escherichia coli E24377A 5590311 YP_001464915.1 CDS EcE24377A_3932 NC_009801.1 3909594 3909710 R identified by glimmer; hypothetical protein complement(3909594..3909710) Escherichia coli E24377A 5587426 YP_001464916.1 CDS livF NC_009801.1 3909777 3910478 R with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3909777..3910478) Escherichia coli E24377A 5587567 YP_001464917.1 CDS livG NC_009801.1 3910492 3911259 R Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3910492..3911259) Escherichia coli E24377A 5587322 YP_001464918.1 CDS livM NC_009801.1 3911256 3912533 R Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit complement(3911256..3912533) Escherichia coli E24377A 5590784 YP_001464919.1 CDS livH NC_009801.1 3912530 3913456 R LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH complement(3912530..3913456) Escherichia coli E24377A 5589770 YP_001464920.1 CDS livK NC_009801.1 3913504 3914613 R identified by match to protein family HMM PF01094; high-affinity branched-chain amino acid ABC transporter periplasmic leucine-specific-binding protein LivK complement(3913504..3914613) Escherichia coli E24377A 5590272 YP_001464921.1 CDS EcE24377A_3938 NC_009801.1 3914765 3914902 R identified by glimmer; hypothetical protein complement(3914765..3914902) Escherichia coli E24377A 5586531 YP_001464922.1 CDS EcE24377A_3940 NC_009801.1 3915037 3915420 D identified by match to protein family HMM PF00583; acetyltransferase 3915037..3915420 Escherichia coli E24377A 5588878 YP_001464923.1 CDS EcE24377A_3939 NC_009801.1 3915417 3915944 R hypothetical protein complement(3915417..3915944) Escherichia coli E24377A 5587903 YP_001464924.1 CDS EcE24377A_3941 NC_009801.1 3915951 3916217 R identified by similarity to GB:AAX67401.1; match to protein family HMM PF08681; hypothetical protein complement(3915951..3916217) Escherichia coli E24377A 5586098 YP_001464925.1 CDS livJ NC_009801.1 3916367 3917470 R identified by match to protein family HMM PF01094; high-affinity branched-chain amino acid ABC transporter periplasmic Leu/Ile/Val-binding protein LivJ complement(3916367..3917470) Escherichia coli E24377A 5590120 YP_001464926.1 CDS rpoH NC_009801.1 3917741 3918595 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(3917741..3918595) Escherichia coli E24377A 5588026 YP_001464927.1 CDS ftsX NC_009801.1 3918840 3919898 R ABC transporter membrane protein; cell division protein FtsX complement(3918840..3919898) Escherichia coli E24377A 5587849 YP_001464928.1 CDS ftsE NC_009801.1 3919891 3920559 R ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE complement(3919891..3920559) Escherichia coli E24377A 5587782 YP_001464929.1 CDS ftsY NC_009801.1 3920562 3922055 R signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY complement(3920562..3922055) Escherichia coli E24377A 5587997 YP_001464930.1 CDS rsmD NC_009801.1 3922205 3922801 D catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 3922205..3922801 Escherichia coli E24377A 5587436 YP_001464931.1 CDS EcE24377A_3948 NC_009801.1 3922791 3923060 D identified by match to protein family HMM PF06611; hypothetical protein 3922791..3923060 Escherichia coli E24377A 5586788 YP_001464932.1 CDS EcE24377A_3949 NC_009801.1 3923063 3923422 R identified by similarity to GB:CAG77246.1; hypothetical protein complement(3923063..3923422) Escherichia coli E24377A 5588999 YP_001464933.1 CDS EcE24377A_3950 NC_009801.1 3923563 3924189 D identified by match to protein family HMM PF07947; hypothetical protein 3923563..3924189 Escherichia coli E24377A 5588751 YP_001464934.1 CDS zntA NC_009801.1 3924263 3926461 D P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 3924263..3926461 Escherichia coli E24377A 5589084 YP_001464935.1 CDS tusA NC_009801.1 3926563 3926808 R TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA complement(3926563..3926808) Escherichia coli E24377A 5589429 YP_001464936.1 CDS EcE24377A_3953 NC_009801.1 3927029 3927694 D identified by match to protein family HMM PF02592; match to protein family HMM TIGR00697; hypothetical protein 3927029..3927694 Escherichia coli E24377A 5586619 YP_001464937.1 CDS EcE24377A_3954 NC_009801.1 3927767 3928324 D hypothetical protein 3927767..3928324 Escherichia coli E24377A 5589379 YP_001464938.1 CDS EcE24377A_3955 NC_009801.1 3928328 3929587 R identified by match to protein family HMM PF07690; major facilitator superfamily transporter complement(3928328..3929587) Escherichia coli E24377A 5590717 YP_001464939.1 CDS EcE24377A_3956 NC_009801.1 3929677 3930726 D identified by match to protein family HMM PF01594; hypothetical protein 3929677..3930726 Escherichia coli E24377A 5587887 YP_001464940.1 CDS acpT NC_009801.1 3930781 3931368 D identified by similarity to SP:P37623; match to protein family HMM PF01648; holo-(acyl carrier protein) synthase 2 3930781..3931368 Escherichia coli E24377A 5589614 YP_001464941.1 CDS nikA NC_009801.1 3931479 3933053 D identified by match to protein family HMM PF00496; match to protein family HMM TIGR02294; nickel ABC transporter periplasmic nickel-binding protein NikA 3931479..3933053 Escherichia coli E24377A 5589100 YP_001464942.1 CDS nikB NC_009801.1 3933053 3933997 D with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 3933053..3933997 Escherichia coli E24377A 5586242 YP_001464943.1 CDS EcE24377A_3960 NC_009801.1 3933978 3934097 D identified by glimmer; hypothetical protein 3933978..3934097 Escherichia coli E24377A 5589652 YP_001464944.1 CDS nikC NC_009801.1 3933994 3934827 D with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 3933994..3934827 Escherichia coli E24377A 5588719 YP_001464945.1 CDS EcE24377A_3961 NC_009801.1 3934760 3935524 R identified by glimmer; hypothetical protein complement(3934760..3935524) Escherichia coli E24377A 5587208 YP_001464946.1 CDS nikD NC_009801.1 3934827 3935591 D with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 3934827..3935591 Escherichia coli E24377A 5587531 YP_001464947.1 CDS nikE NC_009801.1 3935588 3936394 D with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 3935588..3936394 Escherichia coli E24377A 5587320 YP_001464948.1 CDS nikR NC_009801.1 3936400 3936801 D Inhibits transcription at high concentrations of nickel; nickel responsive regulator 3936400..3936801 Escherichia coli E24377A 5588401 YP_001464949.1 CDS EcE24377A_3966 NC_009801.1 3936921 3937280 R identified by match to protein family HMM PF05534; HicB family protein complement(3936921..3937280) Escherichia coli E24377A 5589046 YP_001464950.1 CDS EcE24377A_3967 NC_009801.1 3937611 3938735 R identified by match to protein family HMM PF01061; ABC transporter ATP-binding protein complement(3937611..3938735) Escherichia coli E24377A 5586915 YP_001464951.1 CDS EcE24377A_3968 NC_009801.1 3938735 3941470 R identified by match to protein family HMM PF00005; match to protein family HMM PF01061; ABC transporter ATP-binding protein complement(3938735..3941470) Escherichia coli E24377A 5588680 YP_001464952.1 CDS EcE24377A_3969 NC_009801.1 3941467 3942321 R identified by match to protein family HMM PF00529; MFP family transporter complement(3941467..3942321) Escherichia coli E24377A 5588051 YP_001464953.1 CDS EcE24377A_3970 NC_009801.1 3942687 3944309 R identified by similarity to GB:AAP19219.1; hypothetical protein complement(3942687..3944309) Escherichia coli E24377A 5586363 YP_001464954.1 CDS EcE24377A_3971 NC_009801.1 3944571 3946160 R identified by similarity to GB:AAZ90271.1; hypothetical protein complement(3944571..3946160) Escherichia coli E24377A 5586222 YP_001464955.1 CDS EcE24377A_3972 NC_009801.1 3946544 3947596 D hypothetical protein 3946544..3947596 Escherichia coli E24377A 5586357 YP_001464956.1 CDS EcE24377A_3973 NC_009801.1 3947676 3947789 R identified by glimmer; hypothetical protein complement(3947676..3947789) Escherichia coli E24377A 5590871 YP_001464957.1 CDS EcE24377A_3974 NC_009801.1 3947912 3949114 R identified by match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275; pyridine nucleotide-disulfide oxidoreductase complement(3947912..3949114) Escherichia coli E24377A 5589639 YP_001464958.1 CDS pitA NC_009801.1 3949346 3950845 D identified by match to protein family HMM PF01384; low-affinity inorganic phosphate transporter 1 3949346..3950845 Escherichia coli E24377A 5587621 YP_001464959.1 CDS uspB NC_009801.1 3950916 3951251 R ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB complement(3950916..3951251) Escherichia coli E24377A 5588080 YP_001464960.1 CDS uspA NC_009801.1 3951642 3952076 D identified by similarity to SP:P0AED0; match to protein family HMM PF00582; universal stress protein A 3951642..3952076 Escherichia coli E24377A 5589861 YP_001464961.1 CDS EcE24377A_3978 NC_009801.1 3952394 3953863 D member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 3952394..3953863 Escherichia coli E24377A 5588926 YP_001464962.1 CDS EcE24377A_3979 NC_009801.1 3953912 3954664 R predicted SAM-dependent methyltransferase; methyltransferase complement(3953912..3954664) Escherichia coli E24377A 5586628 YP_001464963.1 CDS prlC NC_009801.1 3954672 3956714 R identified by similarity to SP:P27298; match to protein family HMM PF01432; oligopeptidase A complement(3954672..3956714) Escherichia coli E24377A 5586793 YP_001464964.1 CDS yhiR NC_009801.1 3956917 3957759 D identified by similarity to SP:P37634; match to protein family HMM PF04378; DNA utilization protein YhiR 3956917..3957759 Escherichia coli E24377A 5590657 YP_001464965.1 CDS gor NC_009801.1 3957831 3959183 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 3957831..3959183 Escherichia coli E24377A 5587450 YP_001464966.1 CDS EcE24377A_3983 NC_009801.1 3959237 3959386 R identified by glimmer; hypothetical protein complement(3959237..3959386) Escherichia coli E24377A 5586088 YP_001464967.1 CDS arsR NC_009801.1 3960060 3960413 D regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 3960060..3960413 Escherichia coli E24377A 5588421 YP_001464968.1 CDS arsB NC_009801.1 3960467 3961756 D identified by match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935; arsenical pump membrane protein 3960467..3961756 Escherichia coli E24377A 5588464 YP_001464969.1 CDS arsC NC_009801.1 3961769 3962194 D identified by similarity to SP:P08692; match to protein family HMM PF03960; match to protein family HMM TIGR00014; arsenate reductase 3961769..3962194 Escherichia coli E24377A 5588014 YP_001464970.1 CDS EcE24377A_3988 NC_009801.1 3962227 3962355 D identified by glimmer; hypothetical protein 3962227..3962355 Escherichia coli E24377A 5586565 YP_001464971.1 CDS EcE24377A_3987 NC_009801.1 3962317 3962613 R identified by match to protein family HMM PF01022; ArsR family transcriptional regulator complement(3962317..3962613) Escherichia coli E24377A 5588044 YP_001464972.1 CDS EcE24377A_3989 NC_009801.1 3962721 3963722 D identified by match to protein family HMM PF03773; permease 3962721..3963722 Escherichia coli E24377A 5590462 YP_001464973.1 CDS EcE24377A_3990 NC_009801.1 3964303 3965148 D identified by similarity to GB:ABB67989.1; hypothetical protein 3964303..3965148 Escherichia coli E24377A 5587663 YP_001464974.1 CDS EcE24377A_3991 NC_009801.1 3965343 3965525 D hypothetical protein 3965343..3965525 Escherichia coli E24377A 5590735 YP_001464975.1 CDS EcE24377A_3992 NC_009801.1 3965772 3966338 D identified by match to protein family HMM PF03843; match to protein family HMM TIGR00752; Slp family outer membrane lipoprotein 3965772..3966338 Escherichia coli E24377A 5586106 YP_001464976.1 CDS dctR NC_009801.1 3966494 3967024 D identified by similarity to SP:P37195; match to protein family HMM PF00196; transcriptional regulator DctR 3966494..3967024 Escherichia coli E24377A 5587376 YP_001464977.1 CDS EcE24377A_3994 NC_009801.1 3967066 3967713 R inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase complement(3967066..3967713) Escherichia coli E24377A 5590219 YP_001464978.1 CDS hdeB NC_009801.1 3967777 3968115 R acid-resistance protein complement(3967777..3968115) Escherichia coli E24377A 5586227 YP_001464979.1 CDS hdeA NC_009801.1 3968219 3968551 R inactive form; acid-resistance protein complement(3968219..3968551) Escherichia coli E24377A 5586896 YP_001464980.1 CDS EcE24377A_3997 NC_009801.1 3968806 3969378 D identified by similarity to SP:P0AET7; acid-resistance membrane protein 3968806..3969378 Escherichia coli E24377A 5589825 YP_001464981.1 CDS gadE NC_009801.1 3970177 3970704 D identified by similarity to SP:P63204; transcriptional regulator GadE 3970177..3970704 Escherichia coli E24377A 5588828 YP_001464982.1 CDS mdtE NC_009801.1 3971043 3972200 D with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 3971043..3972200 Escherichia coli E24377A 5586760 YP_001464983.1 CDS mdtF NC_009801.1 3972225 3975338 D identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; multidrug resistance protein MdtF 3972225..3975338 Escherichia coli E24377A 5587271 YP_001464984.1 CDS gadW NC_009801.1 3975701 3976429 R identified by similarity to SP:P63201; match to protein family HMM PF00165; transcriptional regulator GadW complement(3975701..3976429) Escherichia coli E24377A 5587795 YP_001464985.1 CDS EcE24377A_4002 NC_009801.1 3976502 3976609 R identified by glimmer; hypothetical protein complement(3976502..3976609) Escherichia coli E24377A 5586272 YP_001464986.1 CDS gadX NC_009801.1 3976797 3977621 R regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX complement(3976797..3977621) Escherichia coli E24377A 5586574 YP_001464987.1 CDS EcE24377A_4004 NC_009801.1 3977273 3977425 D identified by glimmer; hypothetical protein 3977273..3977425 Escherichia coli E24377A 5586761 YP_001464988.1 CDS gadA NC_009801.1 3977991 3979391 R identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; glutamate decarboxylase complement(3977991..3979391) Escherichia coli E24377A 5588040 YP_001464989.1 CDS treF NC_009801.1 3981403 3983052 D cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 3981403..3983052 Escherichia coli E24377A 5586140 YP_001464990.1 CDS EcE24377A_4008 NC_009801.1 3983103 3983705 R identified by match to protein family HMM PF00196; match to protein family HMM PF04545; match to protein family HMM PF08281; LuxR family transcriptional regulator complement(3983103..3983705) Escherichia coli E24377A 5590700 YP_001464991.1 CDS EcE24377A_4009 NC_009801.1 3984225 3985124 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 3984225..3985124 Escherichia coli E24377A 5590435 YP_001464992.1 CDS EcE24377A_4010 NC_009801.1 3985173 3986186 D identified by match to protein family HMM PF03631; match to protein family HMM TIGR00766; ribonuclease 3985173..3986186 Escherichia coli E24377A 5588056 YP_001464993.1 CDS EcE24377A_4011 NC_009801.1 3986597 3987919 D identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883; MFS transporter metabolite:H+ symporter (MHS) family protein 3986597..3987919 Escherichia coli E24377A 5589409 YP_001464994.1 CDS EcE24377A_4012 NC_009801.1 3988153 3990213 R identified by match to protein family HMM PF05170; AsmA family protein complement(3988153..3990213) Escherichia coli E24377A 5588661 YP_001464995.1 CDS EcE24377A_4013 NC_009801.1 3990283 3991050 R in Escherichia coli this protein is involved in flagellar function; diguanylate phosphodiesterase complement(3990283..3991050) Escherichia coli E24377A 5588366 YP_001464996.1 CDS kdgK NC_009801.1 3991282 3992211 D identified by similarity to SP:P45416; match to protein family HMM PF00294; 2-dehydro-3-deoxygluconokinase 3991282..3992211 Escherichia coli E24377A 5589610 YP_001464997.1 CDS EcE24377A_4015 NC_009801.1 3992307 3993803 R identified by match to protein family HMM PF00675; match to protein family HMM PF05193; M16 family peptidase complement(3992307..3993803) Escherichia coli E24377A 5590422 YP_001464998.1 CDS dctA NC_009801.1 3994024 3995310 R involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA complement(3994024..3995310) Escherichia coli E24377A 5586367 YP_001464999.1 CDS EcE24377A_4017 NC_009801.1 3995493 3997448 R HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase from E. coli; phosphodiesterase complement(3995493..3997448) Escherichia coli E24377A 5587022 YP_001465000.1 CDS bcsC NC_009801.1 3997563 4000985 R cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC complement(3997563..4000985) Escherichia coli E24377A 5590269 YP_001465001.1 CDS bcsZ NC_009801.1 4001018 4002115 R catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase complement(4001018..4002115) Escherichia coli E24377A 5590843 YP_001465002.1 CDS bcsB NC_009801.1 4002131 4004470 R binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein complement(4002131..4004470) Escherichia coli E24377A 5589747 YP_001465003.1 CDS bcsA NC_009801.1 4004481 4007099 R polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit complement(4004481..4007099) Escherichia coli E24377A 5587239 YP_001465004.1 CDS EcE24377A_4022 NC_009801.1 4007096 4007848 R identified by match to protein family HMM PF06564; match to protein family HMM TIGR03371; cell division protein complement(4007096..4007848) Escherichia coli E24377A 5587263 YP_001465005.1 CDS EcE24377A_4023 NC_009801.1 4007860 4008048 R hypothetical protein complement(4007860..4008048) Escherichia coli E24377A 5586933 YP_001465006.1 CDS EcE24377A_4024 NC_009801.1 4008387 4009892 D identified by match to protein family HMM TIGR03369; hypothetical protein 4008387..4009892 Escherichia coli E24377A 5586001 YP_001465007.1 CDS bcsF NC_009801.1 4009889 4010080 D identified by similarity to SP:P0ADJ5; cellulose biosynthesis protein BcsF 4009889..4010080 Escherichia coli E24377A 5588312 YP_001465008.1 CDS EcE24377A_4026 NC_009801.1 4010077 4011756 D identified by similarity to GB:BAB37841.1; match to protein family HMM TIGR03368; hypothetical protein 4010077..4011756 Escherichia coli E24377A 5589700 YP_001465009.1 CDS EcE24377A_4027 NC_009801.1 4012212 4012319 R identified by glimmer; hypothetical protein complement(4012212..4012319) Escherichia coli E24377A 5586144 YP_001465010.1 CDS EcE24377A_4028 NC_009801.1 4012326 4012568 R identified by similarity to GB:AAN45023.1; hypothetical protein complement(4012326..4012568) Escherichia coli E24377A 5590388 YP_001465011.1 CDS EcE24377A_4030 NC_009801.1 4013081 4013242 R identified by glimmer; hypothetical protein complement(4013081..4013242) Escherichia coli E24377A 5589732 YP_001465012.1 CDS EcE24377A_4031 NC_009801.1 4013392 4014663 D identified by match to protein family HMM TIGR00814; serine transporter family protein 4013392..4014663 Escherichia coli E24377A 5589590 YP_001465013.1 CDS dppF NC_009801.1 4014693 4015697 R Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit complement(4014693..4015697) Escherichia coli E24377A 5590444 YP_001465014.1 CDS dppD NC_009801.1 4015694 4016677 R DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit complement(4015694..4016677) Escherichia coli E24377A 5586926 YP_001465015.1 CDS dppC NC_009801.1 4016688 4017590 R identified by match to protein family HMM PF00528; dipeptide transporter complement(4016688..4017590) Escherichia coli E24377A 5587283 YP_001465016.1 CDS dppB NC_009801.1 4017600 4018619 R transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB complement(4017600..4018619) Escherichia coli E24377A 5587393 YP_001465018.1 CDS dppA NC_009801.1 4018927 4020534 R identified by match to protein family HMM PF00496; dipeptide ABC transporter periplasmic dipeptide-binding protein complement(4018927..4020534) Escherichia coli E24377A 5586739 YP_001465019.1 CDS EcE24377A_4038 NC_009801.1 4020723 4020878 D identified by glimmer; hypothetical protein 4020723..4020878 Escherichia coli E24377A 5590617 YP_001465020.1 CDS EcE24377A_4039 NC_009801.1 4021378 4022358 D identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 4021378..4022358 Escherichia coli E24377A 5590623 YP_001465021.1 CDS EcE24377A_4041 NC_009801.1 4022894 4024585 R catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase complement(4022894..4024585) Escherichia coli E24377A 5587933 YP_001465022.1 CDS EcE24377A_4042 NC_009801.1 4024909 4026117 R identified by match to protein family HMM PF07690; match to protein family HMM TIGR00890; major facilitator family transporter complement(4024909..4026117) Escherichia coli E24377A 5588265 YP_001465023.1 CDS EcE24377A_4043 NC_009801.1 4026346 4027044 R identified by similarity to SP:P37663; hypothetical protein complement(4026346..4027044) Escherichia coli E24377A 5589195 YP_001465024.1 CDS tag NC_009801.1 4027202 4027765 D constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyladenine DNA glycosylase 4027202..4027765 Escherichia coli E24377A 5586942 YP_001465025.1 CDS EcE24377A_4046 NC_009801.1 4027762 4028202 D identified by match to protein family HMM PF00583; hypothetical protein 4027762..4028202 Escherichia coli E24377A 5588672 YP_001465026.1 CDS bisC NC_009801.1 4028171 4030504 R identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; biotin sulfoxide reductase complement(4028171..4030504) Escherichia coli E24377A 5586148 YP_001465027.1 CDS EcE24377A_4047 NC_009801.1 4030657 4031316 D identified by similarity to SP:P37665; match to protein family HMM PF00691; match to protein family HMM PF05433; outer membrane lipoprotein 4030657..4031316 Escherichia coli E24377A 5590475 YP_001465028.1 CDS EcE24377A_4048 NC_009801.1 4031332 4031457 D identified by glimmer; hypothetical protein 4031332..4031457 Escherichia coli E24377A 5586839 YP_001465029.1 CDS tkrA NC_009801.1 4031420 4032394 D identified by similarity to SP:P37666; match to protein family HMM PF00389; match to protein family HMM PF02826; 2-ketogluconate reductase 4031420..4032394 Escherichia coli E24377A 5590663 YP_001465030.1 CDS EcE24377A_4050 NC_009801.1 4032444 4033154 R lipoprotein complement(4032444..4033154) Escherichia coli E24377A 5587444 YP_001465031.1 CDS EcE24377A_4051 NC_009801.1 4033588 4033878 D identified by similarity to SP:P0A9V5; transcriptional regulator 4033588..4033878 Escherichia coli E24377A 5586777 YP_001465032.1 CDS EcE24377A_4052 NC_009801.1 4034159 4034371 D identified by match to protein family HMM PF00313; major cold shock protein 4034159..4034371 Escherichia coli E24377A 5588347 YP_001465033.1 CDS hokA NC_009801.1 4034559 4034711 R identified by match to protein family HMM PF01848; small toxic polypeptide complement(4034559..4034711) Escherichia coli E24377A 5590477 YP_001465034.1 CDS glyS NC_009801.1 4035037 4037106 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(4035037..4037106) Escherichia coli E24377A 5589275 YP_001465035.1 CDS glyQ NC_009801.1 4037116 4038027 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(4037116..4038027) Escherichia coli E24377A 5589256 YP_001465036.1 CDS EcE24377A_4056 NC_009801.1 4038122 4038421 R hypothetical protein complement(4038122..4038421) Escherichia coli E24377A 5590703 YP_001465037.1 CDS EcE24377A_4057 NC_009801.1 4038596 4039591 D identified by match to protein family HMM PF01757; acyltransferase 4038596..4039591 Escherichia coli E24377A 5586265 YP_001465038.1 CDS EcE24377A_4058 NC_009801.1 4039633 4040070 R identified by match to protein family HMM PF05360; hypothetical protein complement(4039633..4040070) Escherichia coli E24377A 5590595 YP_001465039.1 CDS EcE24377A_4059 NC_009801.1 4040116 4040457 R identified by match to protein family HMM PF05360; hypothetical protein complement(4040116..4040457) Escherichia coli E24377A 5586253 YP_001465040.1 CDS xylB NC_009801.1 4040626 4042080 R identified by similarity to SP:P29444; match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01312; xylulokinase complement(4040626..4042080) Escherichia coli E24377A 5589269 YP_001465041.1 CDS xylA NC_009801.1 4042152 4043474 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(4042152..4043474) Escherichia coli E24377A 5586302 YP_001465042.1 CDS xylF NC_009801.1 4043840 4044832 D periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 4043840..4044832 Escherichia coli E24377A 5587110 YP_001465043.1 CDS xylG NC_009801.1 4044910 4046451 D with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 4044910..4046451 Escherichia coli E24377A 5589078 YP_001465044.1 CDS xylH NC_009801.1 4046429 4047610 D identified by match to protein family HMM PF02653; D-xylose ABC transporter permease 4046429..4047610 Escherichia coli E24377A 5587482 YP_001465045.1 CDS xylR NC_009801.1 4047688 4048866 D identified by match to protein family HMM PF00165; xylose operon regulatory protein 4047688..4048866 Escherichia coli E24377A 5588910 YP_001465046.1 CDS bax NC_009801.1 4048974 4049798 R identified by match to protein family HMM PF01832; hypothetical protein complement(4048974..4049798) Escherichia coli E24377A 5589839 YP_001465047.1 CDS malS NC_009801.1 4050118 4052148 D periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 4050118..4052148 Escherichia coli E24377A 5588951 YP_001465048.1 CDS avtA NC_009801.1 4052326 4053579 D transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 4052326..4053579 Escherichia coli E24377A 5586081 YP_001465049.1 CDS EcE24377A_4070 NC_009801.1 4053730 4054203 R identified by match to protein family HMM PF00037; 4Fe-4S ferredoxin complement(4053730..4054203) Escherichia coli E24377A 5586395 YP_001465050.1 CDS EcE24377A_4071 NC_009801.1 4054305 4055117 R identified by match to protein family HMM PF01614; match to protein family HMM PF09339; IclR family transcriptional regulator complement(4054305..4055117) Escherichia coli E24377A 5587861 YP_001465051.1 CDS dlgD NC_009801.1 4055354 4056352 D NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 4055354..4056352 Escherichia coli E24377A 5588465 YP_001465052.1 CDS EcE24377A_4073 NC_009801.1 4056364 4056831 D identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 4056364..4056831 Escherichia coli E24377A 5590479 YP_001465053.1 CDS EcE24377A_4074 NC_009801.1 4056949 4057422 D membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease YiaM 4056949..4057422 Escherichia coli E24377A 5588648 YP_001465054.1 CDS EcE24377A_4075 NC_009801.1 4057425 4058702 D identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786; TRAP transporter DctM family protein 4057425..4058702 Escherichia coli E24377A 5590047 YP_001465055.1 CDS yiaO NC_009801.1 4058715 4059701 D identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787; TRAP transporter solute receptor DctP family protein 4058715..4059701 Escherichia coli E24377A 5588362 YP_001465056.1 CDS lyx NC_009801.1 4059705 4061201 D identified by match to protein family HMM PF00370; match to protein family HMM PF02782; cryptic L-xylulose kinase 4059705..4061201 Escherichia coli E24377A 5588113 YP_001465057.1 CDS sgbH NC_009801.1 4061198 4061860 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 4061198..4061860 Escherichia coli E24377A 5589768 YP_001465058.1 CDS EcE24377A_4079 NC_009801.1 4061853 4062713 D L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 4061853..4062713 Escherichia coli E24377A 5586423 YP_001465059.1 CDS sgbE NC_009801.1 4062707 4063402 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4062707..4063402 Escherichia coli E24377A 5588694 YP_001465060.1 CDS EcE24377A_4081 NC_009801.1 4063749 4064489 R identified by match to protein family HMM PF06629; match to protein family HMM TIGR03304; MltA-interacting protein MipA complement(4063749..4064489) Escherichia coli E24377A 5590016 YP_001465061.1 CDS EcE24377A_4083 NC_009801.1 4064613 4065587 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 4064613..4065587 Escherichia coli E24377A 5586579 YP_001465062.1 CDS EcE24377A_4082 NC_009801.1 4065584 4066720 R identified by match to protein family HMM PF00529; membrane fusion protein family protein complement(4065584..4066720) Escherichia coli E24377A 5590282 YP_001465063.1 CDS EcE24377A_4084 NC_009801.1 4066726 4067049 R identified by similarity to GB:AAF95962.1; hypothetical protein complement(4066726..4067049) Escherichia coli E24377A 5590234 YP_001465064.1 CDS EcE24377A_4085 NC_009801.1 4067163 4067375 D identified by glimmer; hypothetical protein 4067163..4067375 Escherichia coli E24377A 5589039 YP_001465065.1 CDS aldB NC_009801.1 4067594 4069132 R identified by similarity to SP:P37685; match to protein family HMM PF00171; aldehyde dehydrogenase complement(4067594..4069132) Escherichia coli E24377A 5589288 YP_001465066.1 CDS adhB NC_009801.1 4069297 4070448 R identified by match to protein family HMM PF00465; alcohol dehydrogenase complement(4069297..4070448) Escherichia coli E24377A 5590691 YP_001465067.1 CDS selB NC_009801.1 4070638 4072482 R identified by similarity to SP:P14081; match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM PF09106; match to protein family HMM PF09107; match to protein family HMM TIGR00475; selenocysteinyl-tRNA-specific translation factor complement(4070638..4072482) Escherichia coli E24377A 5589628 YP_001465068.1 CDS selA NC_009801.1 4072479 4073870 R catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase complement(4072479..4073870) Escherichia coli E24377A 5588280 YP_001465069.1 CDS EcE24377A_4090 NC_009801.1 4073968 4074576 R identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase complement(4073968..4074576) Escherichia coli E24377A 5586688 YP_001465070.1 CDS EcE24377A_4091 NC_009801.1 4074575 4074718 D identified by glimmer; hypothetical protein 4074575..4074718 Escherichia coli E24377A 5587384 YP_001465071.1 CDS EcE24377A_4092 NC_009801.1 4074805 4079040 D identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; protein rhsB 4074805..4079040 Escherichia coli E24377A 5588693 YP_001465072.1 CDS EcE24377A_4093 NC_009801.1 4079500 4080342 D identified by match to protein family HMM PF03130; hypothetical protein 4079500..4080342 Escherichia coli E24377A 5588671 YP_001465073.1 CDS EcE24377A_4094 NC_009801.1 4080384 4081328 D identified by match to protein family HMM PF03527; RHS domain-containing protein 4080384..4081328 Escherichia coli E24377A 5588869 YP_001465074.1 CDS EcE24377A_4095 NC_009801.1 4083405 4084541 R identified by match to protein family HMM PF00529; membrane fusion protein family protein complement(4083405..4084541) Escherichia coli E24377A 5586802 YP_001465075.1 CDS EcE24377A_4096 NC_009801.1 4084544 4084906 R identified by similarity to GB:AAN82851.1; hypothetical protein complement(4084544..4084906) Escherichia coli E24377A 5588077 YP_001465076.1 CDS EcE24377A_4097 NC_009801.1 4084932 4085024 D identified by glimmer; hypothetical protein 4084932..4085024 Escherichia coli E24377A 5588408 YP_001465077.1 CDS mtlA NC_009801.1 4085443 4087356 D identified by match to protein family HMM PF00359; match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851; PTS system mannitol-specific transporter subunit IIABC 4085443..4087356 Escherichia coli E24377A 5590822 YP_001465078.1 CDS mtlD NC_009801.1 4087451 4088599 D identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol-1-phosphate 5-dehydrogenase 4087451..4088599 Escherichia coli E24377A 5588824 YP_001465079.1 CDS mtlR NC_009801.1 4088599 4089186 D Acts as a repressor of the mtlAD operon; mannitol repressor protein 4088599..4089186 Escherichia coli E24377A 5588936 YP_001465080.1 CDS EcE24377A_4101 NC_009801.1 4089198 4089407 R identified by similarity to RF:NP_462588.1; hypothetical protein complement(4089198..4089407) Escherichia coli E24377A 5587850 YP_001465081.1 CDS EcE24377A_4102 NC_009801.1 4089608 4089985 R identified by glimmer; hypothetical protein complement(4089608..4089985) Escherichia coli E24377A 5586568 YP_001465082.1 CDS EcE24377A_4103 NC_009801.1 4089692 4090054 D hypothetical protein 4089692..4090054 Escherichia coli E24377A 5586063 YP_001465083.1 CDS EcE24377A_4104 NC_009801.1 4090140 4090232 R identified by glimmer; hypothetical protein complement(4090140..4090232) Escherichia coli E24377A 5590430 YP_001465084.1 CDS EcE24377A_4105 NC_009801.1 4090597 4091280 D lipoprotein 4090597..4091280 Escherichia coli E24377A 5586207 YP_001465085.1 CDS EcE24377A_4106 NC_009801.1 4091324 4096174 D identified by match to protein family HMM PF03895; match to protein family HMM PF05658; match to protein family HMM PF05662; hemagglutinin/invasin protein 4091324..4096174 Escherichia coli E24377A 5589966 YP_001465086.1 CDS lldP NC_009801.1 4096543 4098198 D identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795; L-lactate permease 4096543..4098198 Escherichia coli E24377A 5588553 YP_001465087.1 CDS EcE24377A_4108 NC_009801.1 4098198 4098974 D represses the lctPRD operon; DNA-binding transcriptional repressor LldR 4098198..4098974 Escherichia coli E24377A 5590775 YP_001465088.1 CDS lldD NC_009801.1 4098971 4100161 D flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 4098971..4100161 Escherichia coli E24377A 5587517 YP_001465089.1 CDS EcE24377A_4110 NC_009801.1 4100347 4100820 D member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 4100347..4100820 Escherichia coli E24377A 5588456 YP_001465090.1 CDS cysE NC_009801.1 4100873 4101694 R catalyzes the O-acetylation of serine; serine acetyltransferase complement(4100873..4101694) Escherichia coli E24377A 5588189 YP_001465091.1 CDS gpsA NC_009801.1 4101774 4102793 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(4101774..4102793) Escherichia coli E24377A 5586380 YP_001465092.1 CDS secB NC_009801.1 4102793 4103260 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(4102793..4103260) Escherichia coli E24377A 5588019 YP_001465093.1 CDS grxC NC_009801.1 4103323 4103574 R identified by similarity to SP:P0AC62; match to protein family HMM PF00462; match to protein family HMM TIGR02181; glutaredoxin 3 complement(4103323..4103574) Escherichia coli E24377A 5590296 YP_001465094.1 CDS EcE24377A_4115 NC_009801.1 4103716 4104147 R identified by match to protein family HMM PF00581; rhodanese domain-containing protein complement(4103716..4104147) Escherichia coli E24377A 5589040 YP_001465095.1 CDS gpmI NC_009801.1 4104392 4105936 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 4104392..4105936 Escherichia coli E24377A 5589900 YP_001465096.2 CDS EcE24377A_4117 NC_009801.1 4105946 4107229 D identified by match to protein family HMM PF01551; hypothetical protein 4105946..4107229 Escherichia coli E24377A 5588453 YP_001465097.1 CDS EcE24377A_4119 NC_009801.1 4107233 4108192 D identified by match to protein family HMM PF04748; polysaccharide deacetylase 4107233..4108192 Escherichia coli E24377A 5586264 YP_001465098.1 CDS EcE24377A_4118 NC_009801.1 4108179 4109213 R identified by match to protein family HMM PF00535; glycosyl transferase family protein complement(4108179..4109213) Escherichia coli E24377A 5589764 YP_001465099.1 CDS tdh NC_009801.1 4109452 4110477 R converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase complement(4109452..4110477) Escherichia coli E24377A 5590371 YP_001465100.1 CDS kbl NC_009801.1 4110487 4111683 R catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase complement(4110487..4111683) Escherichia coli E24377A 5587002 YP_001465101.1 CDS rfaD NC_009801.1 4111897 4112829 D catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 4111897..4112829 Escherichia coli E24377A 5589144 YP_001465102.1 CDS rfaF NC_009801.1 4112839 4113885 D catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 4112839..4113885 Escherichia coli E24377A 5587716 YP_001465103.1 CDS rfaC NC_009801.1 4113889 4114860 D identified by match to protein family HMM PF01075; match to protein family HMM TIGR02193; ADP-heptose--LPS heptosyltransferase 4113889..4114860 Escherichia coli E24377A 5586038 YP_001465104.1 CDS EcE24377A_4125 NC_009801.1 4114930 4116183 R identified by match to protein family HMM PF04932; O-antigen polymerase complement(4114930..4116183) Escherichia coli E24377A 5589715 YP_001465105.1 CDS EcE24377A_4126 NC_009801.1 4116229 4117212 R identified by match to protein family HMM PF00535; glycosyl transferase family protein complement(4116229..4117212) Escherichia coli E24377A 5588064 YP_001465106.1 CDS waaW NC_009801.1 4117297 4118322 R identified by similarity to GB:AAC69673.1; match to protein family HMM PF01501; match to protein family HMM PF08437; lipopolysaccharide 1,2-galactosyltransferase complement(4117297..4118322) Escherichia coli E24377A 5588286 YP_001465107.1 CDS rfaY NC_009801.1 4118348 4119040 R identified by similarity to SP:P27240; match to protein family HMM PF06176; lipopolysaccharide core biosynthesis protein complement(4118348..4119040) Escherichia coli E24377A 5588631 YP_001465108.1 CDS rfaJ NC_009801.1 4119050 4120045 R identified by similarity to SP:P27129; match to protein family HMM PF01501; match to protein family HMM PF08437; lipopolysaccharide 1,2-glucosyltransferase complement(4119050..4120045) Escherichia coli E24377A 5586431 YP_001465109.1 CDS rfaI NC_009801.1 4120062 4121078 R identified by match to protein family HMM PF01501; match to protein family HMM PF08437; lipopolysaccharide 1,3-galactosyltransferase complement(4120062..4121078) Escherichia coli E24377A 5586429 YP_001465110.1 CDS rfaP NC_009801.1 4121094 4121891 R identified by match to protein family HMM PF06293; lipopolysaccharide core biosynthesis protein RfaP complement(4121094..4121891) Escherichia coli E24377A 5588171 YP_001465111.1 CDS rfaG NC_009801.1 4121884 4123008 R identified by similarity to SP:P25740; match to protein family HMM PF00534; lipopolysaccharide core biosynthesis protein RfaG complement(4121884..4123008) Escherichia coli E24377A 5586225 YP_001465112.1 CDS rfaQ NC_009801.1 4123005 4124027 R identified by similarity to SP:P25742; match to protein family HMM PF01075; match to protein family HMM TIGR02201; lipopolysaccharide core biosynthesis protein complement(4123005..4124027) Escherichia coli E24377A 5590050 YP_001465113.1 CDS waaA NC_009801.1 4124476 4125753 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4124476..4125753 Escherichia coli E24377A 5586758 YP_001465114.1 CDS coaD NC_009801.1 4125761 4126240 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4125761..4126240 Escherichia coli E24377A 5590301 YP_001465115.1 CDS mutM NC_009801.1 4126279 4127088 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(4126279..4127088) Escherichia coli E24377A 5588210 YP_001465116.1 CDS rpmG NC_009801.1 4127186 4127353 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(4127186..4127353) Escherichia coli E24377A 5589536 YP_001465117.1 CDS rpmB NC_009801.1 4127374 4127610 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(4127374..4127610) Escherichia coli E24377A 5588436 YP_001465118.1 CDS radC NC_009801.1 4127827 4128495 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(4127827..4128495) Escherichia coli E24377A 5590288 YP_001465119.1 CDS coaBC NC_009801.1 4128667 4129887 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4128667..4129887 Escherichia coli E24377A 5587737 YP_001465120.1 CDS dut NC_009801.1 4129868 4130323 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4129868..4130323 Escherichia coli E24377A 5586080 YP_001465121.1 CDS slmA NC_009801.1 4130430 4131026 D FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4130430..4131026 Escherichia coli E24377A 5588015 YP_001465122.1 CDS pyrE NC_009801.1 4131063 4131704 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(4131063..4131704) Escherichia coli E24377A 5589603 YP_001465123.1 CDS rph NC_009801.1 4131770 4132486 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(4131770..4132486) Escherichia coli E24377A 5589981 YP_001465124.1 CDS EcE24377A_4145 NC_009801.1 4132613 4133476 D identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255; hypothetical protein 4132613..4133476 Escherichia coli E24377A 5589558 YP_001465125.1 CDS EcE24377A_4146 NC_009801.1 4133493 4133633 R identified by glimmer; hypothetical protein complement(4133493..4133633) Escherichia coli E24377A 5588688 YP_001465126.1 CDS dinD NC_009801.1 4133697 4134521 D identified by similarity to SP:P23840; DNA-damage-inducible protein D 4133697..4134521 Escherichia coli E24377A 5586843 YP_001465127.1 CDS EcE24377A_4149 NC_009801.1 4134813 4135430 D identified by match to protein family HMM PF03458; hypothetical protein 4134813..4135430 Escherichia coli E24377A 5589413 YP_001465128.1 CDS ligB NC_009801.1 4135427 4137115 R this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB complement(4135427..4137115) Escherichia coli E24377A 5589251 YP_001465129.1 CDS gmk NC_009801.1 4137367 4137990 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4137367..4137990 Escherichia coli E24377A 5586292 YP_001465130.1 CDS rpoZ NC_009801.1 4138045 4138320 D promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4138045..4138320 Escherichia coli E24377A 5590309 YP_001465131.1 CDS spoT NC_009801.1 4138339 4140447 D identified by similarity to SP:P17580; match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4138339..4140447 Escherichia coli E24377A 5586755 YP_001465132.1 CDS trmH NC_009801.1 4140454 4141143 D specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4140454..4141143 Escherichia coli E24377A 5586829 YP_001465133.1 CDS recG NC_009801.1 4141149 4143230 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4141149..4143230 Escherichia coli E24377A 5590655 YP_001465134.1 CDS EcE24377A_4155 NC_009801.1 4143215 4144081 R identified by similarity to GB:AAG58797.1; hypothetical protein complement(4143215..4144081) Escherichia coli E24377A 5587389 YP_001465135.1 CDS gltS NC_009801.1 4144084 4145289 R identified by similarity to SP:P0AER8; match to protein family HMM PF03616; match to protein family HMM TIGR00210; sodium/glutamate symporter complement(4144084..4145289) Escherichia coli E24377A 5587149 YP_001465136.1 CDS yicE NC_009801.1 4145569 4146960 D identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; xanthine permease 4145569..4146960 Escherichia coli E24377A 5590394 YP_001465137.1 CDS EcE24377A_4159 NC_009801.1 4147081 4148790 D identified by match to protein family HMM PF05170; AsmA family protein 4147081..4148790 Escherichia coli E24377A 5587366 YP_001465138.1 CDS yicI NC_009801.1 4148843 4151161 R catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase complement(4148843..4151161) Escherichia coli E24377A 5588392 YP_001465139.1 CDS EcE24377A_4162 NC_009801.1 4151129 4151269 D identified by glimmer; hypothetical protein 4151129..4151269 Escherichia coli E24377A 5589578 YP_001465140.1 CDS EcE24377A_4161 NC_009801.1 4151171 4152610 R may be involved in the transport of galactosides-pentoses-hexuronides; transporter complement(4151171..4152610) Escherichia coli E24377A 5590473 YP_001465141.1 CDS EcE24377A_4165 NC_009801.1 4153479 4153613 D identified by glimmer; hypothetical protein 4153479..4153613 Escherichia coli E24377A 5586501 YP_001465142.1 CDS setC NC_009801.1 4153576 4154760 D identified by match to protein family HMM PF07690; match to protein family HMM TIGR00899; sugar efflux transporter C 4153576..4154760 Escherichia coli E24377A 5588998 YP_001465143.1 CDS EcE24377A_4167 NC_009801.1 4154871 4155794 D identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950; carboxylate/amino acid/amine transporter 4154871..4155794 Escherichia coli E24377A 5587840 YP_001465144.1 CDS nlpA NC_009801.1 4155798 4156616 R identified by similarity to SP:P04846; match to protein family HMM PF03180; match to protein family HMM TIGR00363; hypothetical protein complement(4155798..4156616) Escherichia coli E24377A 5589053 YP_001465145.1 CDS EcE24377A_4169 NC_009801.1 4156838 4157131 D identified by similarity to SP:Q5PC60; hypothetical protein 4156838..4157131 Escherichia coli E24377A 5590593 YP_001465146.1 CDS nepI NC_009801.1 4157172 4158527 R experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter complement(4157172..4158527) Escherichia coli E24377A 5589851 YP_001465147.1 CDS EcE24377A_4171 NC_009801.1 4158573 4159025 R identified by match to protein family HMM PF06711; hypothetical protein complement(4158573..4159025) Escherichia coli E24377A 5590215 YP_001465148.1 CDS EcE24377A_4172 NC_009801.1 4159078 4160490 R identified by match to protein family HMM PF00860; match to protein family HMM PF00916; sulfate permease inorganic anion transporter complement(4159078..4160490) Escherichia coli E24377A 5589637 YP_001465149.1 CDS ade NC_009801.1 4160587 4162353 D catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4160587..4162353 Escherichia coli E24377A 5587057 YP_001465150.1 CDS uhpT NC_009801.1 4162398 4163789 R cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter complement(4162398..4163789) Escherichia coli E24377A 5588881 YP_001465151.1 CDS uhpC NC_009801.1 4163927 4165246 R membrane protein regulates uhpT expression; regulatory protein UhpC complement(4163927..4165246) Escherichia coli E24377A 5588544 YP_001465152.1 CDS uhpB NC_009801.1 4165256 4166749 R Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB complement(4165256..4166749) Escherichia coli E24377A 5589042 YP_001465153.1 CDS EcE24377A_4177 NC_009801.1 4166658 4166771 R identified by glimmer; hypothetical protein complement(4166658..4166771) Escherichia coli E24377A 5588125 YP_001465154.1 CDS uhpA NC_009801.1 4166758 4167348 R response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA complement(4166758..4167348) Escherichia coli E24377A 5586219 YP_001465155.1 CDS ilvN NC_009801.1 4167422 4167712 R with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit complement(4167422..4167712) Escherichia coli E24377A 5587810 YP_001465156.1 CDS ilvB NC_009801.1 4167716 4169404 R identified by similarity to SP:P08142; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118; acetolactate synthase catalytic subunit complement(4167716..4169404) Escherichia coli E24377A 5588193 YP_001465157.1 CDS emrD NC_009801.1 4170681 4171865 D multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4170681..4171865 Escherichia coli E24377A 5590054 YP_001465158.1 CDS EcE24377A_4182 NC_009801.1 4171873 4172370 R hypothetical protein complement(4171873..4172370) Escherichia coli E24377A 5586290 YP_001465159.1 CDS EcE24377A_4183 NC_009801.1 4172367 4172729 R hypothetical protein complement(4172367..4172729) Escherichia coli E24377A 5588520 YP_001465160.1 CDS EcE24377A_4184 NC_009801.1 4172719 4173066 R identified by match to protein family HMM PF02656; hypothetical protein complement(4172719..4173066) Escherichia coli E24377A 5588413 YP_001465161.1 CDS EcE24377A_4185 NC_009801.1 4173176 4173625 D identified by similarity to SP:P31446; hypothetical protein 4173176..4173625 Escherichia coli E24377A 5586787 YP_001465162.1 CDS EcE24377A_4186 NC_009801.1 4173672 4175165 R identified by match to protein family HMM PF00884; sulfatase complement(4173672..4175165) Escherichia coli E24377A 5590158 YP_001465163.1 CDS EcE24377A_4187 NC_009801.1 4175162 4176877 R uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK complement(4175162..4176877) Escherichia coli E24377A 5590129 YP_001465164.1 CDS EcE24377A_4189 NC_009801.1 4177044 4177937 D identified by match to protein family HMM PF00165; AraC family transcriptional regulator 4177044..4177937 Escherichia coli E24377A 5588211 YP_001465165.1 CDS EcE24377A_4190 NC_009801.1 4178748 4180625 R identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00852; match to protein family HMM TIGR02005; PTS system, alpha-glucoside-specific transporter subunit IIBC complement(4178748..4180625) Escherichia coli E24377A 5588151 YP_001465166.1 CDS EcE24377A_4192 NC_009801.1 4180660 4181376 D identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 4180660..4181376 Escherichia coli E24377A 5589076 YP_001465167.1 CDS EcE24377A_4191 NC_009801.1 4181373 4183034 R identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625; hypothetical protein complement(4181373..4183034) Escherichia coli E24377A 5587290 YP_001465168.1 CDS EcE24377A_4193 NC_009801.1 4183065 4183226 D identified by glimmer; hypothetical protein 4183065..4183226 Escherichia coli E24377A 5590351 YP_001465169.1 CDS ibpB NC_009801.1 4183231 4183659 R 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB complement(4183231..4183659) Escherichia coli E24377A 5586090 YP_001465170.1 CDS ibpA NC_009801.1 4183771 4184184 R with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA complement(4183771..4184184) Escherichia coli E24377A 5587526 YP_001465171.1 CDS EcE24377A_4196 NC_009801.1 4184383 4184475 R identified by glimmer; hypothetical protein complement(4184383..4184475) Escherichia coli E24377A 5588584 YP_001465172.1 CDS EcE24377A_4197 NC_009801.1 4184415 4184822 D identified by match to protein family HMM PF07119; hypothetical protein 4184415..4184822 Escherichia coli E24377A 5590817 YP_001465173.1 CDS EcE24377A_4198 NC_009801.1 4184824 4186038 R identified by similarity to GB:ABB64081.1; hypothetical protein complement(4184824..4186038) Escherichia coli E24377A 5587855 YP_001465174.1 CDS EcE24377A_4200 NC_009801.1 4186139 4187203 D FAD/NAD(P)-binding domain; oxidoreductase 4186139..4187203 Escherichia coli E24377A 5590811 YP_001465175.1 CDS EcE24377A_4199 NC_009801.1 4187200 4188537 R identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00881; match to protein family HMM TIGR00893; d-galactonate transporter complement(4187200..4188537) Escherichia coli E24377A 5586560 YP_001465176.1 CDS EcE24377A_4201 NC_009801.1 4188612 4189760 R identified by match to protein family HMM PF01188; match to protein family HMM PF02746; galactonate dehydratase complement(4188612..4189760) Escherichia coli E24377A 5588263 YP_001465177.1 CDS EcE24377A_4202 NC_009801.1 4189757 4190374 R catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(4189757..4190374) Escherichia coli E24377A 5589400 YP_001465178.1 CDS dgoK NC_009801.1 4190358 4191236 R identified by match to protein family HMM PF05035; 2-dehydro-3-deoxygalactonokinase complement(4190358..4191236) Escherichia coli E24377A 5587555 YP_001465179.1 CDS dgoR NC_009801.1 4191233 4191922 R identified by match to protein family HMM PF00392; match to protein family HMM PF07729; galactonate operon transcriptional repressor complement(4191233..4191922) Escherichia coli E24377A 5587248 YP_001465180.1 CDS EcE24377A_4205 NC_009801.1 4192095 4192856 D hypothetical protein 4192095..4192856 Escherichia coli E24377A 5590517 YP_001465181.1 CDS yidA NC_009801.1 4192902 4193714 R YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase complement(4192902..4193714) Escherichia coli E24377A 5590202 YP_001465182.1 CDS EcE24377A_4207 NC_009801.1 4193829 4194227 R yidB; identified by match to protein family HMM PF06078; hypothetical protein complement(4193829..4194227) Escherichia coli E24377A 5588024 YP_001465183.1 CDS EcE24377A_4208 NC_009801.1 4194360 4194461 D identified by glimmer; hypothetical protein 4194360..4194461 Escherichia coli E24377A 5586701 YP_001465184.1 CDS gyrB NC_009801.1 4194467 4196881 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(4194467..4196881) Escherichia coli E24377A 5589170 YP_001465185.1 CDS recF NC_009801.1 4196910 4197983 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(4196910..4197983) Escherichia coli E24377A 5590164 YP_001465186.1 CDS dnaN NC_009801.1 4197983 4199083 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(4197983..4199083) Escherichia coli E24377A 5589967 YP_001465187.1 CDS dnaA NC_009801.1 4199088 4200491 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein complement(4199088..4200491) Escherichia coli E24377A 5590505 YP_001465188.1 CDS rpmH NC_009801.1 4201098 4201238 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4201098..4201238 Escherichia coli E24377A 5586371 YP_001465189.1 CDS rnpA NC_009801.1 4201255 4201614 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4201255..4201614 Escherichia coli E24377A 5588609 YP_001465190.1 CDS EcE24377A_4215 NC_009801.1 4201838 4203484 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4201838..4203484 Escherichia coli E24377A 5588964 YP_001465191.1 CDS trmE NC_009801.1 4203590 4204954 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4203590..4204954 Escherichia coli E24377A 5588223 YP_001465192.1 CDS tnaA NC_009801.1 4205492 4206907 D tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4205492..4206907 Escherichia coli E24377A 5587073 YP_001465193.1 CDS tnaB NC_009801.1 4206998 4208245 D tryptophan transporter of low affinity; tryptophan permease TnaB 4206998..4208245 Escherichia coli E24377A 5586347 YP_001465194.1 CDS mdtL NC_009801.1 4208377 4209552 D Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4208377..4209552 Escherichia coli E24377A 5587247 YP_001465195.1 CDS EcE24377A_4220 NC_009801.1 4209527 4210486 D Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4209527..4210486 Escherichia coli E24377A 5587986 YP_001465196.1 CDS EcE24377A_4221 NC_009801.1 4210643 4211392 D identified by similarity to GB:AAP19005.1; hypothetical protein 4210643..4211392 Escherichia coli E24377A 5588368 YP_001465197.1 CDS EcE24377A_4222 NC_009801.1 4211414 4211980 D identified by match to protein family HMM PF03358; NADPH-dependent FMN reductase 4211414..4211980 Escherichia coli E24377A 5587701 YP_001465198.1 CDS EcE24377A_4223 NC_009801.1 4212034 4213371 R identified by match to protein family HMM PF00860; sulfate permease inorganic anion transporter complement(4212034..4213371) Escherichia coli E24377A 5588577 YP_001465199.1 CDS yieH NC_009801.1 4213538 4214203 D YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4213538..4214203 Escherichia coli E24377A 5587065 YP_001465200.1 CDS EcE24377A_4225 NC_009801.1 4214270 4214743 D might be involved in hypersensitivity to nitrofurzone; inner membrane protein 4214270..4214743 Escherichia coli E24377A 5587913 YP_001465201.1 CDS EcE24377A_4226 NC_009801.1 4214792 4215379 D identified by similarity to SP:P31469; match to protein family HMM PF03691; hypothetical protein 4214792..4215379 Escherichia coli E24377A 5590464 YP_001465202.1 CDS EcE24377A_4227 NC_009801.1 4215441 4216163 R identified by match to protein family HMM PF01182; 6-phosphogluconolactonase complement(4215441..4216163) Escherichia coli E24377A 5585907 YP_001465203.1 CDS EcE24377A_4228 NC_009801.1 4216178 4217272 R identified by match to protein family HMM PF00756; match to protein family HMM PF02922; esterase complement(4216178..4217272) Escherichia coli E24377A 5586379 YP_001465204.1 CDS bglH NC_009801.1 4217374 4218990 R identified by similarity to SP:P26218; match to protein family HMM PF02264; glucoside specific outer membrane porin BglH complement(4217374..4218990) Escherichia coli E24377A 5586912 YP_001465205.1 CDS EcE24377A_4230 NC_009801.1 4219076 4220470 R identified by match to protein family HMM PF00232; 6-phospho-beta-glucosidase complement(4219076..4220470) Escherichia coli E24377A 5590178 YP_001465206.1 CDS bglF NC_009801.1 4220489 4222366 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunit IIABC complement(4220489..4222366) Escherichia coli E24377A 5586356 YP_001465207.1 CDS EcE24377A_4232 NC_009801.1 4221600 4221731 D identified by glimmer; hypothetical protein 4221600..4221731 Escherichia coli E24377A 5589366 YP_001465208.1 CDS EcE24377A_4233 NC_009801.1 4222500 4223336 R positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG complement(4222500..4223336) Escherichia coli E24377A 5589621 YP_001465209.1 CDS EcE24377A_4234 NC_009801.1 4223402 4223524 D identified by glimmer; hypothetical protein 4223402..4223524 Escherichia coli E24377A 5588140 YP_001465210.1 CDS phoU NC_009801.1 4223622 4224347 R regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU complement(4223622..4224347) Escherichia coli E24377A 5588486 YP_001465211.1 CDS pstB NC_009801.1 4224362 4225135 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(4224362..4225135) Escherichia coli E24377A 5590447 YP_001465212.1 CDS pstA NC_009801.1 4225226 4226116 R Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA complement(4225226..4226116) Escherichia coli E24377A 5586936 YP_001465213.1 CDS pstC NC_009801.1 4226116 4227075 R part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC complement(4226116..4227075) Escherichia coli E24377A 5590578 YP_001465214.1 CDS pstS NC_009801.1 4227162 4228202 R identified by match to protein family HMM PF01547; match to protein family HMM TIGR00975; phosphate ABC transporter substrate-binding protein complement(4227162..4228202) Escherichia coli E24377A 5588454 YP_001465215.1 CDS EcE24377A_4240 NC_009801.1 4228450 4229523 R identified by match to protein family HMM PF00419; fimbrial family protein complement(4228450..4229523) Escherichia coli E24377A 5588311 YP_001465216.1 CDS fimD1 NC_009801.1 4229534 4232053 R identified by similarity to SP:P30130; match to protein family HMM PF00577; outer membrane usher protein FimD complement(4229534..4232053) Escherichia coli E24377A 5587626 YP_001465217.1 CDS EcE24377A_4242 NC_009801.1 4232081 4232812 R identified by match to protein family HMM PF00345; match to protein family HMM PF02753; pili assembly chaperone protein complement(4232081..4232812) Escherichia coli E24377A 5590800 YP_001465218.1 CDS EcE24377A_4243 NC_009801.1 4232860 4233432 R identified by match to protein family HMM PF00419; fimbrial protein complement(4232860..4233432) Escherichia coli E24377A 5587515 YP_001465219.1 CDS glmS NC_009801.1 4233734 4235563 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(4233734..4235563) Escherichia coli E24377A 5586069 YP_001465220.1 CDS glmU NC_009801.1 4235725 4237095 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(4235725..4237095) Escherichia coli E24377A 5586055 YP_001465221.1 CDS EcE24377A_4248 NC_009801.1 4237365 4237889 D identified by glimmer; hypothetical protein 4237365..4237889 Escherichia coli E24377A 5587570 YP_001465222.1 CDS atpC NC_009801.1 4237446 4237865 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon complement(4237446..4237865) Escherichia coli E24377A 5587812 YP_001465223.1 CDS atpD NC_009801.1 4237886 4239268 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta complement(4237886..4239268) Escherichia coli E24377A 5588798 YP_001465224.1 CDS atpG NC_009801.1 4239295 4240158 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma complement(4239295..4240158) Escherichia coli E24377A 5586118 YP_001465225.1 CDS atpA NC_009801.1 4240209 4241750 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha complement(4240209..4241750) Escherichia coli E24377A 5588038 YP_001465226.1 CDS atpH NC_009801.1 4241763 4242296 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta complement(4241763..4242296) Escherichia coli E24377A 5586867 YP_001465227.1 CDS atpF NC_009801.1 4242311 4242781 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B complement(4242311..4242781) Escherichia coli E24377A 5589230 YP_001465228.1 CDS atpE NC_009801.1 4242843 4243082 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C complement(4242843..4243082) Escherichia coli E24377A 5589010 YP_001465229.1 CDS atpB NC_009801.1 4243129 4243944 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A complement(4243129..4243944) Escherichia coli E24377A 5587259 YP_001465230.1 CDS atpI NC_009801.1 4243953 4244333 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(4243953..4244333) Escherichia coli E24377A 5586609 YP_001465231.1 CDS gidA NC_009801.1 4245641 4247530 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(4245641..4247530) Escherichia coli E24377A 5590214 YP_001465232.1 CDS mioC NC_009801.1 4247909 4248352 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(4247909..4248352) Escherichia coli E24377A 5590124 YP_001465233.1 CDS asnC NC_009801.1 4248442 4248900 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(4248442..4248900) Escherichia coli E24377A 5588587 YP_001465234.1 CDS asnA NC_009801.1 4249052 4250044 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4249052..4250044 Escherichia coli E24377A 5589505 YP_001465235.1 CDS yieM NC_009801.1 4250049 4251500 R contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein complement(4250049..4251500) Escherichia coli E24377A 5587769 YP_001465236.1 CDS EcE24377A_4262 NC_009801.1 4251494 4252990 R interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA complement(4251494..4252990) Escherichia coli E24377A 5589531 YP_001465237.1 CDS trkD NC_009801.1 4253213 4255081 D Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4253213..4255081 Escherichia coli E24377A 5587761 YP_001465238.1 CDS rbsD NC_009801.1 4255248 4255667 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4255248..4255667 Escherichia coli E24377A 5589927 YP_001465239.1 CDS rbsA NC_009801.1 4255675 4257180 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 4255675..4257180 Escherichia coli E24377A 5587294 YP_001465240.1 CDS rbsC NC_009801.1 4257185 4258150 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4257185..4258150 Escherichia coli E24377A 5589292 YP_001465241.1 CDS rbsB NC_009801.1 4258181 4259065 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4258181..4259065 Escherichia coli E24377A 5589708 YP_001465242.1 CDS rbsK NC_009801.1 4259191 4260120 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4259191..4260120 Escherichia coli E24377A 5590231 YP_001465243.1 CDS rbsR NC_009801.1 4260124 4261116 D DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4260124..4261116 Escherichia coli E24377A 5587721 YP_001465244.1 CDS EcE24377A_4269 NC_009801.1 4261082 4262485 R identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; DHA2 family drug:H+ antiporter-1 complement(4261082..4262485) Escherichia coli E24377A 5587387 YP_001465245.1 CDS EcE24377A_4271 NC_009801.1 4262532 4263224 R identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator complement(4262532..4263224) Escherichia coli E24377A 5587859 YP_001465246.1 CDS hdfR NC_009801.1 4269025 4269864 R Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR complement(4269025..4269864) Escherichia coli E24377A 5586547 YP_001465247.1 CDS EcE24377A_4277 NC_009801.1 4269983 4270321 D identified by similarity to GB:AAZ90461.1; match to protein family HMM PF04219; hypothetical protein 4269983..4270321 Escherichia coli E24377A 5586274 YP_001465248.1 CDS EcE24377A_4278 NC_009801.1 4270347 4271867 R among the AAA+ ATPases, the YifB protease belongs to the Helix 2 insert clade; unknown function; ATP-dependent protease complement(4270347..4271867) Escherichia coli E24377A 5588438 YP_001465249.1 CDS ilvG NC_009801.1 4272458 4274104 D catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4272458..4274104 Escherichia coli E24377A 5590788 YP_001465250.1 CDS ilvM NC_009801.1 4274101 4274364 D identified by similarity to SP:P0ADG3; acetolactate synthase 2 regulatory subunit 4274101..4274364 Escherichia coli E24377A 5586651 YP_001465251.1 CDS ilvE NC_009801.1 4274384 4275313 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4274384..4275313 Escherichia coli E24377A 5587062 YP_001465252.1 CDS ilvD NC_009801.1 4275378 4277228 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4275378..4277228 Escherichia coli E24377A 5589972 YP_001465253.1 CDS ilvA NC_009801.1 4277231 4278775 D threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4277231..4278775 Escherichia coli E24377A 5590154 YP_001465254.1 CDS ilvY NC_009801.1 4278772 4279662 R participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY complement(4278772..4279662) Escherichia coli E24377A 5586725 YP_001465255.1 CDS ilvC NC_009801.1 4279812 4281287 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4279812..4281287 Escherichia coli E24377A 5590085 YP_001465256.1 CDS ppiC NC_009801.1 4281374 4281655 R identified by match to protein family HMM PF00639; peptidyl-prolyl cis-trans isomerase C complement(4281374..4281655) Escherichia coli E24377A 5586105 YP_001465257.1 CDS EcE24377A_4287 NC_009801.1 4281854 4282303 R identified by similarity to GB:BAC41601.1; hypothetical protein complement(4281854..4282303) Escherichia coli E24377A 5587249 YP_001465258.1 CDS rep NC_009801.1 4282520 4284541 D single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4282520..4284541 Escherichia coli E24377A 5589259 YP_001465259.1 CDS gppA NC_009801.1 4284588 4286072 R catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase complement(4284588..4286072) Escherichia coli E24377A 5587305 YP_001465260.1 CDS EcE24377A_4291 NC_009801.1 4286178 4286276 D identified by glimmer; hypothetical protein 4286178..4286276 Escherichia coli E24377A 5587825 YP_001465261.1 CDS rhlB NC_009801.1 4286206 4287471 R enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB complement(4286206..4287471) Escherichia coli E24377A 5586486 YP_001465262.1 CDS trxA NC_009801.1 4287602 4287931 D identified by similarity to SP:P0AA25; match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 4287602..4287931 Escherichia coli E24377A 5590840 YP_001465263.1 CDS rho NC_009801.1 4288258 4289517 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4288258..4289517 Escherichia coli E24377A 5587858 YP_001465264.1 CDS EcE24377A_4294 NC_009801.1 4289527 4289745 D identified by glimmer; hypothetical protein 4289527..4289745 Escherichia coli E24377A 5588238 YP_001465265.1 CDS wecA NC_009801.1 4289757 4290860 D identified by match to protein family HMM PF00953; match to protein family HMM TIGR02380; undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase 4289757..4290860 Escherichia coli E24377A 5590619 YP_001465266.1 CDS EcE24377A_4296 NC_009801.1 4290872 4291918 D Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4290872..4291918 Escherichia coli E24377A 5586465 YP_001465267.1 CDS EcE24377A_4297 NC_009801.1 4291974 4293104 D identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236; UDP-N-acetylglucosamine 2-epimerase 4291974..4293104 Escherichia coli E24377A 5587937 YP_001465268.1 CDS wecC NC_009801.1 4293101 4294363 D catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4293101..4294363 Escherichia coli E24377A 5587224 YP_001465269.1 CDS rfbB1 NC_009801.1 4294363 4295430 D identified by similarity to SP:P27830; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; dTDP-glucose 4,6-dehydratase 4294363..4295430 Escherichia coli E24377A 5590411 YP_001465270.1 CDS rfbA2 NC_009801.1 4295449 4296330 D identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidylyltransferase 4295449..4296330 Escherichia coli E24377A 5587539 YP_001465271.1 CDS wecD NC_009801.1 4296437 4296982 D identified by match to protein family HMM PF00583; match to protein family HMM TIGR02382; TDP-fucosamine acetyltransferase 4296437..4296982 Escherichia coli E24377A 5589330 YP_001465272.1 CDS wecE NC_009801.1 4296987 4298117 D catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4296987..4298117 Escherichia coli E24377A 5589928 YP_001465273.1 CDS EcE24377A_4304 NC_009801.1 4298119 4299369 D polysaccharide biosynthesis protein 4298119..4299369 Escherichia coli E24377A 5586713 YP_001465274.1 CDS EcE24377A_4303 NC_009801.1 4299318 4299410 R identified by glimmer; hypothetical protein complement(4299318..4299410) Escherichia coli E24377A 5587432 YP_001465275.1 CDS wecF NC_009801.1 4299366 4300445 D catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4299366..4300445 Escherichia coli E24377A 5590275 YP_001465276.1 CDS wzyE NC_009801.1 4300442 4301794 D enterobacterial common antigen polymerase; common antigen polymerase 4300442..4301794 Escherichia coli E24377A 5588568 YP_001465277.1 CDS EcE24377A_4307 NC_009801.1 4301797 4302537 D identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696; UDP-N-acetyl-D-mannosaminuronic acid transferase 4301797..4302537 Escherichia coli E24377A 5587375 YP_001465278.1 CDS EcE24377A_4308 NC_009801.1 4302608 4302706 R identified by glimmer; hypothetical protein complement(4302608..4302706) Escherichia coli E24377A 5585962 YP_001465279.1 CDS EcE24377A_4309 NC_009801.1 4302728 4304113 D uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transporter 4302728..4304113 Escherichia coli E24377A 5587804 YP_001465280.1 CDS aslB NC_009801.1 4304799 4306034 D ydeM; identified by similarity to SP:P25550; match to protein family HMM PF04055; arylsulfatase 4304799..4306034 Escherichia coli E24377A 5588766 YP_001465281.1 CDS EcE24377A_4315 NC_009801.1 4306118 4306279 R arylsulfatase complement(4306118..4306279) Escherichia coli E24377A 5588320 YP_001465282.1 CDS EcE24377A_4316 NC_009801.1 4306422 4306559 R identified by glimmer; hypothetical protein complement(4306422..4306559) Escherichia coli E24377A 5590680 YP_001465283.1 CDS hemY NC_009801.1 4306958 4308154 R identified by match to protein family HMM PF07219; match to protein family HMM PF07719; match to protein family HMM TIGR00540; protoheme IX biogenesis protein complement(4306958..4308154) Escherichia coli E24377A 5585971 YP_001465284.1 CDS EcE24377A_4318 NC_009801.1 4308157 4309350 R identified by match to protein family HMM PF04375; uroporphyrinogen III C-methyltransferase complement(4308157..4309350) Escherichia coli E24377A 5588114 YP_001465285.1 CDS hemD NC_009801.1 4309372 4310112 R catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase complement(4309372..4310112) Escherichia coli E24377A 5589588 YP_001465286.1 CDS hemC NC_009801.1 4310109 4311071 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(4310109..4311071) Escherichia coli E24377A 5587255 YP_001465287.1 CDS cyaA NC_009801.1 4311437 4313983 D catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4311437..4313983 Escherichia coli E24377A 5590660 YP_001465288.1 CDS cyaY NC_009801.1 4314023 4314343 R defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein complement(4314023..4314343) Escherichia coli E24377A 5590095 YP_001465289.1 CDS EcE24377A_4323 NC_009801.1 4314391 4315704 R hypothetical protein complement(4314391..4315704) Escherichia coli E24377A 5587446 YP_001465290.1 CDS EcE24377A_4324 NC_009801.1 4315701 4317179 R lipoprotein complement(4315701..4317179) Escherichia coli E24377A 5589147 YP_001465291.1 CDS EcE24377A_4326 NC_009801.1 4318108 4318242 R identified by glimmer; hypothetical protein complement(4318108..4318242) Escherichia coli E24377A 5590601 YP_001465292.1 CDS EcE24377A_4327 NC_009801.1 4318451 4318654 D lipoprotein 4318451..4318654 Escherichia coli E24377A 5587331 YP_001465293.1 CDS dapF NC_009801.1 4318691 4319515 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4318691..4319515 Escherichia coli E24377A 5589486 YP_001465294.1 CDS EcE24377A_4329 NC_009801.1 4319512 4320219 D identified by match to protein family HMM PF04340; hypothetical protein 4319512..4320219 Escherichia coli E24377A 5590328 YP_001465295.1 CDS xerC NC_009801.1 4320216 4321112 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4320216..4321112 Escherichia coli E24377A 5589813 YP_001465296.1 CDS EcE24377A_4331 NC_009801.1 4321112 4321828 D YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4321112..4321828 Escherichia coli E24377A 5589618 YP_001465297.1 CDS uvrD NC_009801.1 4321912 4324074 D unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4321912..4324074 Escherichia coli E24377A 5586191 YP_001465298.1 CDS EcE24377A_4333 NC_009801.1 4324221 4324985 R hypothetical protein complement(4324221..4324985) Escherichia coli E24377A 5587000 YP_001465299.1 CDS EcE24377A_4334 NC_009801.1 4324977 4325111 D identified by glimmer; hypothetical protein 4324977..4325111 Escherichia coli E24377A 5588514 YP_001465300.1 CDS corA NC_009801.1 4325355 4326305 D responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4325355..4326305 Escherichia coli E24377A 5586723 YP_001465301.1 CDS EcE24377A_4337 NC_009801.1 4326311 4326412 D identified by glimmer; hypothetical protein 4326311..4326412 Escherichia coli E24377A 5590077 YP_001465302.1 CDS EcE24377A_4336 NC_009801.1 4326359 4326838 R identified by match to protein family HMM PF06092; hypothetical protein complement(4326359..4326838) Escherichia coli E24377A 5589381 YP_001465303.1 CDS EcE24377A_4338 NC_009801.1 4326835 4327683 R identified by match to protein family HMM TIGR03034; hypothetical protein complement(4326835..4327683) Escherichia coli E24377A 5590332 YP_001465304.1 CDS EcE24377A_4339 NC_009801.1 4327813 4328016 D identified by glimmer; hypothetical protein 4327813..4328016 Escherichia coli E24377A 5587503 YP_001465305.1 CDS rarD NC_009801.1 4328986 4329873 R identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688; RarD protein complement(4328986..4329873) Escherichia coli E24377A 5587972 YP_001465306.1 CDS EcE24377A_4341 NC_009801.1 4329925 4330410 R identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein complement(4329925..4330410) Escherichia coli E24377A 5589693 YP_001465307.1 CDS pldA NC_009801.1 4330557 4331426 D catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4330557..4331426 Escherichia coli E24377A 5588306 YP_001465308.1 CDS recQ NC_009801.1 4331559 4333388 D functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4331559..4333388 Escherichia coli E24377A 5587866 YP_001465309.1 CDS rhtC NC_009801.1 4333458 4334072 D identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949; threonine efflux system 4333458..4334072 Escherichia coli E24377A 5586324 YP_001465310.1 CDS rhtB NC_009801.1 4334134 4334754 R identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949; homoserine/homoserine lactone efflux protein complement(4334134..4334754) Escherichia coli E24377A 5590291 YP_001465311.1 CDS pldB NC_009801.1 4334865 4335887 D lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4334865..4335887 Escherichia coli E24377A 5589489 YP_001465312.1 CDS EcE24377A_4347 NC_009801.1 4335895 4336695 D purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4335895..4336695 Escherichia coli E24377A 5586182 YP_001465313.1 CDS EcE24377A_4349 NC_009801.1 4336771 4337670 D identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950; drug/metabolite exporter (DME) family protein 4336771..4337670 Escherichia coli E24377A 5589318 YP_001465314.1 CDS metR NC_009801.1 4337558 4338511 R identified by similarity to SP:P0A9F9; match to protein family HMM PF00126; match to protein family HMM PF03466; transcriptional regulator MetR complement(4337558..4338511) Escherichia coli E24377A 5590391 YP_001465315.1 CDS metE NC_009801.1 4338628 4340889 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 4338628..4340889 Escherichia coli E24377A 5589931 YP_001465316.1 CDS EcE24377A_4351 NC_009801.1 4340928 4341743 R identified by match to protein family HMM PF01738; dienelactone hydrolase complement(4340928..4341743) Escherichia coli E24377A 5587571 YP_001465317.1 CDS udp NC_009801.1 4342005 4342766 D catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4342005..4342766 Escherichia coli E24377A 5590005 YP_001465318.1 CDS rmuC NC_009801.1 4342907 4344334 D YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4342907..4344334 Escherichia coli E24377A 5589322 YP_001465319.1 CDS ubiE NC_009801.1 4344429 4345184 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4344429..4345184 Escherichia coli E24377A 5589519 YP_001465320.1 CDS EcE24377A_4355 NC_009801.1 4345198 4345803 D identified by match to protein family HMM PF06843; hypothetical protein 4345198..4345803 Escherichia coli E24377A 5590166 YP_001465321.1 CDS ubiB NC_009801.1 4345800 4347440 D an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4345800..4347440 Escherichia coli E24377A 5590769 YP_001465322.1 CDS tatA NC_009801.1 4347519 4347788 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase A 4347519..4347788 Escherichia coli E24377A 5586210 YP_001465323.1 CDS tatB NC_009801.1 4347792 4348307 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4347792..4348307 Escherichia coli E24377A 5588484 YP_001465324.1 CDS tatC NC_009801.1 4348310 4349086 D with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4348310..4349086 Escherichia coli E24377A 5587619 YP_001465325.1 CDS tatD NC_009801.1 4349128 4349910 D magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4349128..4349910 Escherichia coli E24377A 5587005 YP_001465326.1 CDS rfaH NC_009801.1 4349907 4350395 R identified by similarity to SP:P26614; match to protein family HMM PF02357; match to protein family HMM TIGR01955; transcriptional activator RfaH complement(4349907..4350395) Escherichia coli E24377A 5586647 YP_001465327.1 CDS ubiD NC_009801.1 4350562 4352055 D catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4350562..4352055 Escherichia coli E24377A 5586698 YP_001465328.1 CDS fre NC_009801.1 4352101 4352802 D NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4352101..4352802 Escherichia coli E24377A 5587770 YP_001465329.1 CDS fadA NC_009801.1 4352994 4354157 R FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase complement(4352994..4354157) Escherichia coli E24377A 5587876 YP_001465330.1 CDS fadB NC_009801.1 4354167 4356356 R includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha complement(4354167..4356356) Escherichia coli E24377A 5586338 YP_001465331.1 CDS pepQ NC_009801.1 4356546 4357877 D catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4356546..4357877 Escherichia coli E24377A 5589989 YP_001465332.1 CDS EcE24377A_4367 NC_009801.1 4357874 4358491 D identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257; hypothetical protein 4357874..4358491 Escherichia coli E24377A 5588005 YP_001465333.1 CDS trkH NC_009801.1 4358530 4359981 D identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933; potassium transporter 4358530..4359981 Escherichia coli E24377A 5589751 YP_001465334.1 CDS hemG NC_009801.1 4359993 4360538 D catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4359993..4360538 Escherichia coli E24377A 5590419 YP_001465335.1 CDS mobB NC_009801.1 4366119 4366646 R in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B complement(4366119..4366646) Escherichia coli E24377A 5587993 YP_001465336.1 CDS mobA NC_009801.1 4366628 4367212 R in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA complement(4366628..4367212) Escherichia coli E24377A 5586816 YP_001465337.1 CDS EcE24377A_4375 NC_009801.1 4367261 4367362 R identified by glimmer; hypothetical protein complement(4367261..4367362) Escherichia coli E24377A 5587463 YP_001465338.1 CDS EcE24377A_4376 NC_009801.1 4367282 4367551 D identified by match to protein family HMM PF06288; hypothetical protein 4367282..4367551 Escherichia coli E24377A 5587734 YP_001465339.1 CDS EcE24377A_4377 NC_009801.1 4367628 4368614 D catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4367628..4368614 Escherichia coli E24377A 5590295 YP_001465340.1 CDS dsbA NC_009801.1 4368631 4369257 D identified by similarity to SP:P52235; match to protein family HMM PF01323; protein disulfide isomerase I 4368631..4369257 Escherichia coli E24377A 5590815 YP_001465341.1 CDS EcE24377A_4379 NC_009801.1 4369412 4370842 D yihF; identified by match to protein family HMM PF06097; hypothetical protein 4369412..4370842 Escherichia coli E24377A 5586857 YP_001465342.1 CDS EcE24377A_4380 NC_009801.1 4370883 4371788 R identified by match to protein family HMM PF01553; acyltransferase complement(4370883..4371788) Escherichia coli E24377A 5586611 YP_001465343.1 CDS EcE24377A_4381 NC_009801.1 4371935 4372177 R identified by glimmer; hypothetical protein complement(4371935..4372177) Escherichia coli E24377A 5588790 YP_001465344.1 CDS polA NC_009801.1 4372179 4374965 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4372179..4374965 Escherichia coli E24377A 5587789 YP_001465345.1 CDS engB NC_009801.1 4375347 4375979 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(4375347..4375979) Escherichia coli E24377A 5587230 YP_001465346.1 CDS EcE24377A_4384 NC_009801.1 4376561 4377070 D identified by similarity to SP:Q8FBG9; match to protein family HMM PF04220; hypothetical protein 4376561..4377070 Escherichia coli E24377A 5586884 YP_001465347.1 CDS EcE24377A_4385 NC_009801.1 4377144 4377260 R identified by glimmer; hypothetical protein complement(4377144..4377260) Escherichia coli E24377A 5586964 YP_001465348.1 CDS hemN NC_009801.1 4377259 4378632 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4377259..4378632 Escherichia coli E24377A 5588897 YP_001465349.1 CDS EcE24377A_4387 NC_009801.1 4378678 4378782 R identified by glimmer; hypothetical protein complement(4378678..4378782) Escherichia coli E24377A 5588259 YP_001465350.1 CDS EcE24377A_4389 NC_009801.1 4378822 4378932 R identified by glimmer; hypothetical protein complement(4378822..4378932) Escherichia coli E24377A 5587791 YP_001465351.1 CDS glnG NC_009801.1 4379044 4380453 R response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) complement(4379044..4380453) Escherichia coli E24377A 5590155 YP_001465352.1 CDS glnL NC_009801.1 4380465 4381514 R sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) complement(4380465..4381514) Escherichia coli E24377A 5588647 YP_001465353.1 CDS glnA NC_009801.1 4381688 4383097 R forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase complement(4381688..4383097) Escherichia coli E24377A 5587551 YP_001465354.1 CDS EcE24377A_4393 NC_009801.1 4383087 4383197 R identified by glimmer; hypothetical protein complement(4383087..4383197) Escherichia coli E24377A 5587321 YP_001465355.1 CDS typA NC_009801.1 4383470 4385293 D identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394; GTP-binding protein 4383470..4385293 Escherichia coli E24377A 5590541 YP_001465356.1 CDS EcE24377A_4395 NC_009801.1 4385510 4386220 D identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 4385510..4386220 Escherichia coli E24377A 5588141 YP_001465357.1 CDS EcE24377A_4396 NC_009801.1 4386228 4387208 D identified by match to protein family HMM PF01261; AP endonuclease 4386228..4387208 Escherichia coli E24377A 5587760 YP_001465358.1 CDS EcE24377A_4397 NC_009801.1 4387310 4388575 D identified by match to protein family HMM PF07690; major facilitator transporter 4387310..4388575 Escherichia coli E24377A 5586720 YP_001465359.1 CDS ompL NC_009801.1 4388666 4389358 R porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown; outer membrane porin L complement(4388666..4389358) Escherichia coli E24377A 5588129 YP_001465360.1 CDS EcE24377A_4399 NC_009801.1 4389426 4390829 R identified by match to protein family HMM TIGR00792; sugar (glycoside-Pentoside-hexuronide) transporter family protein complement(4389426..4390829) Escherichia coli E24377A 5588729 YP_001465361.1 CDS EcE24377A_4400 NC_009801.1 4390872 4392278 R identified by match to protein family HMM TIGR00792; sugar transporter family protein complement(4390872..4392278) Escherichia coli E24377A 5585904 YP_001465362.1 CDS EcE24377A_4401 NC_009801.1 4392303 4394339 R identified by match to protein family HMM PF01055; alpha-glucosidase complement(4392303..4394339) Escherichia coli E24377A 5590243 YP_001465363.1 CDS EcE24377A_4402 NC_009801.1 4394538 4395440 R identified by match to protein family HMM PF01263; aldose-1-epimerase complement(4394538..4395440) Escherichia coli E24377A 5587930 YP_001465364.1 CDS EcE24377A_4403 NC_009801.1 4395578 4396819 R identified by match to protein family HMM PF07221; N-acylglucosamine 2-epimerase complement(4395578..4396819) Escherichia coli E24377A 5590230 YP_001465365.1 CDS EcE24377A_4404 NC_009801.1 4396836 4397714 R identified by match to protein family HMM PF01791; deoxyribose-phosphate aldolase complement(4396836..4397714) Escherichia coli E24377A 5589704 YP_001465366.1 CDS EcE24377A_4405 NC_009801.1 4397738 4398634 R identified by match to protein family HMM PF03446; 3-hydroxyisobutyrate dehydrogenase complement(4397738..4398634) Escherichia coli E24377A 5586650 YP_001465367.1 CDS EcE24377A_4406 NC_009801.1 4398802 4399698 D identified by match to protein family HMM PF00294; PfkB family kinase 4398802..4399698 Escherichia coli E24377A 5586745 YP_001465368.1 CDS EcE24377A_4407 NC_009801.1 4399732 4400517 D identified by match to protein family HMM PF00455; match to protein family HMM PF01022; match to protein family HMM PF08220; match to protein family HMM PF08279; DeoR family transcriptional regulator 4399732..4400517 Escherichia coli E24377A 5587985 YP_001465369.1 CDS yihX NC_009801.1 4400616 4401215 D identified by similarity to SP:P0A8Y4; match to protein family HMM PF00702; match to protein family HMM TIGR01509; phosphatase 4400616..4401215 Escherichia coli E24377A 5589943 YP_001465370.1 CDS rbn NC_009801.1 4401209 4402081 D RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4401209..4402081 Escherichia coli E24377A 5586676 YP_001465371.1 CDS dtd NC_009801.1 4402078 4402515 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4402078..4402515 Escherichia coli E24377A 5588466 YP_001465372.1 CDS EcE24377A_4411 NC_009801.1 4402560 4403501 D identified by match to protein family HMM PF00583; match to protein family HMM TIGR02447; thioesterase/acetyltransferase domain-containing protein 4402560..4403501 Escherichia coli E24377A 5587563 YP_001465373.1 CDS EcE24377A_4412 NC_009801.1 4403565 4404473 R identified by match to protein family HMM PF07859; alpha/beta hydrolase complement(4403565..4404473) Escherichia coli E24377A 5587718 YP_001465374.1 CDS EcE24377A_4413 NC_009801.1 4404487 4404585 D identified by glimmer; hypothetical protein 4404487..4404585 Escherichia coli E24377A 5590445 YP_001465375.1 CDS EcE24377A_4414 NC_009801.1 4404702 4405013 D identified by similarity to GB:AAN83266.1; hypothetical protein 4404702..4405013 Escherichia coli E24377A 5589297 YP_001465376.1 CDS EcE24377A_4415 NC_009801.1 4405014 4405304 D identified by match to protein family HMM PF01381; helix-turn-helix DNA-binding domain-containing protein 4405014..4405304 Escherichia coli E24377A 5587768 YP_001465377.1 CDS EcE24377A_4416 NC_009801.1 4405390 4405482 D identified by glimmer; hypothetical protein 4405390..4405482 Escherichia coli E24377A 5588304 YP_001465378.1 CDS EcE24377A_4418 NC_009801.1 4406346 4406588 D hypothetical protein 4406346..4406588 Escherichia coli E24377A 5587122 YP_001465379.1 CDS EcE24377A_4419 NC_009801.1 4406817 4407797 R identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase complement(4406817..4407797) Escherichia coli E24377A 5590831 YP_001465380.1 CDS fdhE NC_009801.1 4408196 4409125 R required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE complement(4408196..4409125) Escherichia coli E24377A 5590649 YP_001465381.1 CDS fdoI NC_009801.1 4409122 4409757 R cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma complement(4409122..4409757) Escherichia coli E24377A 5588174 YP_001465382.1 CDS fdoH NC_009801.1 4409754 4410656 R identified by similarity to SP:P0AAJ5; match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582; formate dehydrogenase-O, iron-sulfur subunit complement(4409754..4410656) Escherichia coli E24377A 5590333 YP_001465383.1 CDS EcE24377A_4424 NC_009801.1 4413723 4413977 D identified by glimmer; hypothetical protein 4413723..4413977 Escherichia coli E24377A 5585993 YP_001465384.1 CDS fdhD NC_009801.1 4413946 4414746 D involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4413946..4414746 Escherichia coli E24377A 5589082 YP_001465385.1 CDS EcE24377A_4426 NC_009801.1 4414899 4415939 D lipoprotein 4414899..4415939 Escherichia coli E24377A 5588566 YP_001465386.1 CDS EcE24377A_4427 NC_009801.1 4415989 4417737 R repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; frv operon regulatory protein complement(4415989..4417737) Escherichia coli E24377A 5588925 YP_001465387.1 CDS EcE24377A_4428 NC_009801.1 4417737 4418807 R with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars; fructose-specific phosphotransferase system protein FrvX complement(4417737..4418807) Escherichia coli E24377A 5586970 YP_001465388.1 CDS EcE24377A_4429 NC_009801.1 4418797 4420248 R identified by match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR01427; PTS system transporter subunits IIBC complement(4418797..4420248) Escherichia coli E24377A 5586988 YP_001465389.1 CDS EcE24377A_4430 NC_009801.1 4420259 4420705 R with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; fructose-like phosphotransferase system subunit EIIA complement(4420259..4420705) Escherichia coli E24377A 5588973 YP_001465390.1 CDS EcE24377A_4431 NC_009801.1 4420895 4421005 R identified by glimmer; hypothetical protein complement(4420895..4421005) Escherichia coli E24377A 5586033 YP_001465391.1 CDS rhaU NC_009801.1 4421006 4421320 R identified by match to protein family HMM PF05336; match to protein family HMM TIGR02625; L-rhamnose 1-epimerase complement(4421006..4421320) Escherichia coli E24377A 5589784 YP_001465392.1 CDS rhaD NC_009801.1 4421330 4422154 R identified by similarity to SP:P32169; match to protein family HMM PF00596; match to protein family HMM TIGR02624; rhamnulose-1-phosphate aldolase complement(4421330..4422154) Escherichia coli E24377A 5590040 YP_001465393.1 CDS rhaA NC_009801.1 4422396 4423655 R catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase complement(4422396..4423655) Escherichia coli E24377A 5587921 YP_001465394.1 CDS rhaB NC_009801.1 4423652 4425121 R catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase complement(4423652..4425121) Escherichia coli E24377A 5589027 YP_001465395.1 CDS EcE24377A_4436 NC_009801.1 4425200 4425349 D identified by glimmer; hypothetical protein 4425200..4425349 Escherichia coli E24377A 5588285 YP_001465396.1 CDS rhaS NC_009801.1 4425409 4426245 D activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4425409..4426245 Escherichia coli E24377A 5588150 YP_001465397.1 CDS rhaR NC_009801.1 4426229 4427167 D activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4426229..4427167 Escherichia coli E24377A 5589229 YP_001465398.1 CDS rhaT NC_009801.1 4427164 4428198 R transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter complement(4427164..4428198) Escherichia coli E24377A 5586208 YP_001465399.1 CDS sodA NC_009801.1 4428483 4429103 D SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4428483..4429103 Escherichia coli E24377A 5588968 YP_001465400.1 CDS EcE24377A_4441 NC_009801.1 4429144 4429260 R hypothetical protein complement(4429144..4429260) Escherichia coli E24377A 5587642 YP_001465401.1 CDS EcE24377A_4442 NC_009801.1 4429278 4429385 D identified by glimmer; hypothetical protein 4429278..4429385 Escherichia coli E24377A 5586493 YP_001465402.1 CDS kdgT NC_009801.1 4429363 4430346 D transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4429363..4430346 Escherichia coli E24377A 5589901 YP_001465403.1 CDS EcE24377A_4444 NC_009801.1 4430495 4431169 D identified by match to protein family HMM PF03473; match to protein family HMM PF03475; hypothetical protein 4430495..4431169 Escherichia coli E24377A 5589811 YP_001465404.1 CDS cpxA NC_009801.1 4431275 4432648 R part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein complement(4431275..4432648) Escherichia coli E24377A 5586803 YP_001465405.1 CDS cpxR NC_009801.1 4432645 4433343 R response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR complement(4432645..4433343) Escherichia coli E24377A 5587169 YP_001465406.1 CDS cpxP NC_009801.1 4433493 4433993 D repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP 4433493..4433993 Escherichia coli E24377A 5587510 YP_001465407.1 CDS fieF NC_009801.1 4434142 4435044 D member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4434142..4435044 Escherichia coli E24377A 5586159 YP_001465408.1 CDS pfkA NC_009801.1 4435225 4436187 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4435225..4436187 Escherichia coli E24377A 5590315 YP_001465409.1 CDS EcE24377A_4450 NC_009801.1 4436213 4436356 R identified by glimmer; hypothetical protein complement(4436213..4436356) Escherichia coli E24377A 5590048 YP_001465410.1 CDS sbp NC_009801.1 4436507 4437496 D identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971; sulfate transporter subunit 4436507..4437496 Escherichia coli E24377A 5586871 YP_001465411.1 CDS cdh NC_009801.1 4437603 4438358 D identified by match to protein family HMM PF02611; match to protein family HMM TIGR00672; CDP-diacylglycerol pyrophosphatase 4437603..4438358 Escherichia coli E24377A 5590584 YP_001465412.1 CDS tpiA NC_009801.1 4438413 4439180 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(4438413..4439180) Escherichia coli E24377A 5587727 YP_001465413.1 CDS EcE24377A_4454 NC_009801.1 4439288 4439887 R identified by match to protein family HMM PF07305; hypothetical protein complement(4439288..4439887) Escherichia coli E24377A 5588102 YP_001465414.1 CDS EcE24377A_4455 NC_009801.1 4439988 4440428 D identified by match to protein family HMM PF05656; hypothetical protein 4439988..4440428 Escherichia coli E24377A 5590570 YP_001465415.1 CDS EcE24377A_4456 NC_009801.1 4440640 4440939 D identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743; hypothetical protein 4440640..4440939 Escherichia coli E24377A 5587232 YP_001465416.1 CDS uspD NC_009801.1 4440966 4441394 D with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4440966..4441394 Escherichia coli E24377A 5587254 YP_001465417.1 CDS fpr NC_009801.1 4441399 4442145 R identified by similarity to SP:P28861; match to protein family HMM PF00175; match to protein family HMM PF00970; ferredoxin-NADP reductase complement(4441399..4442145) Escherichia coli E24377A 5589500 YP_001465418.1 CDS glpX NC_009801.1 4442242 4443252 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(4442242..4443252) Escherichia coli E24377A 5586019 YP_001465419.1 CDS glpK NC_009801.1 4443388 4444896 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(4443388..4444896) Escherichia coli E24377A 5588294 YP_001465420.1 CDS glpF NC_009801.1 4444919 4445764 R identified by similarity to SP:P31140; match to protein family HMM PF00230; match to protein family HMM TIGR00861; glycerol uptake facilitator protein complement(4444919..4445764) Escherichia coli E24377A 5586042 YP_001465421.1 CDS EcE24377A_4462 NC_009801.1 4446001 4446102 D identified by glimmer; hypothetical protein 4446001..4446102 Escherichia coli E24377A 5588890 YP_001465422.1 CDS EcE24377A_4463 NC_009801.1 4446195 4446434 D identified by match to protein family HMM PF06005; hypothetical protein 4446195..4446434 Escherichia coli E24377A 5590620 YP_001465423.1 CDS rraA NC_009801.1 4446519 4447004 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(4446519..4447004) Escherichia coli E24377A 5588713 YP_001465424.1 CDS menA NC_009801.1 4447097 4448023 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(4447097..4448023) Escherichia coli E24377A 5585930 YP_001465425.1 CDS hslU NC_009801.1 4448090 4449421 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(4448090..4449421) Escherichia coli E24377A 5587633 YP_001465426.1 CDS hslV NC_009801.1 4449431 4449961 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(4449431..4449961) Escherichia coli E24377A 5589988 YP_001465427.1 CDS ftsN NC_009801.1 4450054 4451013 R identified by similarity to SP:P29131; match to protein family HMM PF05036; match to protein family HMM TIGR02223; essential cell division protein FtsN complement(4450054..4451013) Escherichia coli E24377A 5587596 YP_001465428.1 CDS cytR NC_009801.1 4451105 4452130 R negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR complement(4451105..4452130) Escherichia coli E24377A 5589376 YP_001465429.1 CDS priA NC_009801.1 4452286 4454484 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(4452286..4454484) Escherichia coli E24377A 5586752 YP_001465430.1 CDS rpmE NC_009801.1 4454687 4454899 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 4454687..4454899 Escherichia coli E24377A 5586378 YP_001465431.1 CDS EcE24377A_4473 NC_009801.1 4455059 4459156 D identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; protein rhsA 4455059..4459156 Escherichia coli E24377A 5588654 YP_001465432.1 CDS EcE24377A_4474 NC_009801.1 4460283 4460384 R lipoprotein complement(4460283..4460384) Escherichia coli E24377A 5590677 YP_001465433.1 CDS EcE24377A_4475 NC_009801.1 4460388 4460996 R member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase complement(4460388..4460996) Escherichia coli E24377A 5587545 YP_001465434.1 CDS EcE24377A_4476 NC_009801.1 4461009 4461125 D identified by glimmer; hypothetical protein 4461009..4461125 Escherichia coli E24377A 5590761 YP_001465435.1 CDS EcE24377A_4477 NC_009801.1 4461223 4462206 R identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase complement(4461223..4462206) Escherichia coli E24377A 5587383 YP_001465436.1 CDS metJ NC_009801.1 4462454 4462771 R when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ complement(4462454..4462771) Escherichia coli E24377A 5590023 YP_001465437.1 CDS metB NC_009801.1 4463048 4464208 D catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4463048..4464208 Escherichia coli E24377A 5586065 YP_001465438.1 CDS metL NC_009801.1 4464211 4466643 D multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4464211..4466643 Escherichia coli E24377A 5586852 YP_001465439.1 CDS metF NC_009801.1 4466992 4467882 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4466992..4467882 Escherichia coli E24377A 5589665 YP_001465440.1 CDS katG NC_009801.1 4468211 4470391 D identified by similarity to SP:P13029; match to protein family HMM PF00141; match to protein family HMM TIGR00198; catalase/peroxidase HPI 4468211..4470391 Escherichia coli E24377A 5590644 YP_001465441.1 CDS EcE24377A_4483 NC_009801.1 4470485 4471390 D identified by similarity to SP:P0ABT8; match to protein family HMM PF00892; transporter 4470485..4471390 Escherichia coli E24377A 5590466 YP_001465442.1 CDS EcE24377A_4484 NC_009801.1 4471417 4472034 R identified by similarity to GB:AAZ90633.1; match to protein family HMM PF06940; hypothetical protein complement(4471417..4472034) Escherichia coli E24377A 5587677 YP_001465443.1 CDS gldA NC_009801.1 4472309 4473412 R forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase complement(4472309..4473412) Escherichia coli E24377A 5587967 YP_001465444.1 CDS fsaB NC_009801.1 4473423 4474085 R similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase complement(4473423..4474085) Escherichia coli E24377A 5590076 YP_001465445.1 CDS ptsA NC_009801.1 4474097 4476598 R identified by similarity to SP:P32670; match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; multi-phosphoryl transfer protein 2 complement(4474097..4476598) Escherichia coli E24377A 5586169 YP_001465446.1 CDS EcE24377A_4488 NC_009801.1 4476907 4477986 D FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 4476907..4477986 Escherichia coli E24377A 5590480 YP_001465447.1 CDS EcE24377A_4489 NC_009801.1 4478001 4478321 D FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; PTS system fructose-like transporter subunit EIIB 4478001..4478321 Escherichia coli E24377A 5586345 YP_001465448.1 CDS pflD NC_009801.1 4478372 4480669 D involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 4478372..4480669 Escherichia coli E24377A 5589713 YP_001465449.1 CDS EcE24377A_4491 NC_009801.1 4480635 4481513 D identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494; pyruvate formate lyase II activase 4480635..4481513 Escherichia coli E24377A 5590566 YP_001465450.1 CDS EcE24377A_4493 NC_009801.1 4481515 4481856 D FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 4481515..4481856 Escherichia coli E24377A 5587066 YP_001465451.1 CDS EcE24377A_4492 NC_009801.1 4481843 4482694 R identified by match to protein family HMM PF00165; AraC family transcriptional regulator complement(4481843..4482694) Escherichia coli E24377A 5589048 YP_001465452.1 CDS EcE24377A_4494 NC_009801.1 4482843 4484576 R identified by match to protein family HMM PF00884; hypothetical protein complement(4482843..4484576) Escherichia coli E24377A 5586271 YP_001465453.1 CDS ppc NC_009801.1 4484759 4487410 R catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(4484759..4487410) Escherichia coli E24377A 5586747 YP_001465454.1 CDS argE NC_009801.1 4487762 4488913 R catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase complement(4487762..4488913) Escherichia coli E24377A 5588158 YP_001465455.1 CDS argC NC_009801.1 4489067 4490071 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4489067..4490071 Escherichia coli E24377A 5589679 YP_001465456.1 CDS argB NC_009801.1 4490082 4490855 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4490082..4490855 Escherichia coli E24377A 5588239 YP_001465457.1 CDS argH NC_009801.1 4490916 4492289 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4490916..4492289 Escherichia coli E24377A 5587646 YP_001465458.1 CDS rspA2 NC_009801.1 4492787 4494001 D identified by match to protein family HMM PF01188; match to protein family HMM PF02746; starvation sensing protein 4492787..4494001 Escherichia coli E24377A 5590245 YP_001465459.1 CDS EcE24377A_4501 NC_009801.1 4494068 4495351 D identified by match to protein family HMM PF07690; phthalate permease 4494068..4495351 Escherichia coli E24377A 5587717 YP_001465460.1 CDS oxyR NC_009801.1 4495602 4496519 D Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4495602..4496519 Escherichia coli E24377A 5587079 YP_001465461.1 CDS sthA NC_009801.1 4496502 4497902 R catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase complement(4496502..4497902) Escherichia coli E24377A 5587637 YP_001465462.1 CDS fabR NC_009801.1 4498236 4498883 D negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4498236..4498883 Escherichia coli E24377A 5587480 YP_001465463.1 CDS EcE24377A_4505 NC_009801.1 4498883 4499242 D identified by match to protein family HMM PF07226; hypothetical protein 4498883..4499242 Escherichia coli E24377A 5589535 YP_001465464.1 CDS trmA NC_009801.1 4499282 4500382 R catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase complement(4499282..4500382) Escherichia coli E24377A 5588094 YP_001465465.1 CDS btuB NC_009801.1 4500751 4502595 D involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4500751..4502595 Escherichia coli E24377A 5586885 YP_001465466.1 CDS murI NC_009801.1 4502540 4503397 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4502540..4503397 Escherichia coli E24377A 5587187 YP_001465467.1 CDS murB NC_009801.1 4509083 4510111 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4509083..4510111 Escherichia coli E24377A 5589351 YP_001465468.1 CDS birA NC_009801.1 4510108 4511073 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4510108..4511073 Escherichia coli E24377A 5589743 YP_001465469.1 CDS coaA NC_009801.1 4511102 4512052 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(4511102..4512052) Escherichia coli E24377A 5587359 YP_001465470.1 CDS EcE24377A_4514 NC_009801.1 4512109 4512270 R identified by glimmer; hypothetical protein complement(4512109..4512270) Escherichia coli E24377A 5585902 YP_001465471.1 CDS tuf2 NC_009801.1 4512970 4514154 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4512970..4514154 Escherichia coli E24377A 5586136 YP_001465472.1 CDS secE NC_009801.1 4514384 4514767 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4514384..4514767 Escherichia coli E24377A 5589680 YP_001465473.1 CDS nusG NC_009801.1 4514769 4515314 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4514769..4515314 Escherichia coli E24377A 5589655 YP_001465474.1 CDS EcE24377A_4522 NC_009801.1 4515419 4516420 R identified by similarity to GB:AAN83366.1; hypothetical protein complement(4515419..4516420) Escherichia coli E24377A 5590043 YP_001465475.1 CDS rplK NC_009801.1 4515473 4515901 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4515473..4515901 Escherichia coli E24377A 5586405 YP_001465476.1 CDS rplA NC_009801.1 4515905 4516609 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4515905..4516609 Escherichia coli E24377A 5586349 YP_001465477.1 CDS rplJ NC_009801.1 4517022 4517519 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4517022..4517519 Escherichia coli E24377A 5587474 YP_001465478.1 CDS EcE24377A_4526 NC_009801.1 4517571 4518077 R identified by glimmer; hypothetical protein complement(4517571..4518077) Escherichia coli E24377A 5589253 YP_001465479.1 CDS rplL NC_009801.1 4517586 4517951 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4517586..4517951 Escherichia coli E24377A 5587845 YP_001465480.1 CDS rpoB NC_009801.1 4518271 4522299 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4518271..4522299 Escherichia coli E24377A 5590109 YP_001465481.1 CDS rpoC NC_009801.1 4522376 4526599 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4522376..4526599 Escherichia coli E24377A 5589321 YP_001465482.1 CDS htrC NC_009801.1 4526812 4527351 D identified by similarity to SP:P27375; heat shock protein 4526812..4527351 Escherichia coli E24377A 5590774 YP_001465483.1 CDS thiH NC_009801.1 4527761 4528894 R in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH complement(4527761..4528894) Escherichia coli E24377A 5586259 YP_001465484.1 CDS thiG NC_009801.1 4528891 4529661 R functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase complement(4528891..4529661) Escherichia coli E24377A 5587209 YP_001465485.1 CDS thiS NC_009801.1 4529663 4529863 R with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS complement(4529663..4529863) Escherichia coli E24377A 5588279 YP_001465486.1 CDS thiF NC_009801.1 4529847 4530602 R identified by similarity to SP:P30138; match to protein family HMM PF00899; match to protein family HMM PF05237; match to protein family HMM TIGR02356; thiazole biosynthesis adenylyltransferase ThiF complement(4529847..4530602) Escherichia coli E24377A 5587549 YP_001465487.1 CDS thiE NC_009801.1 4530595 4531230 R catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase complement(4530595..4531230) Escherichia coli E24377A 5589036 YP_001465488.1 CDS thiC NC_009801.1 4531230 4533125 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(4531230..4533125) Escherichia coli E24377A 5590823 YP_001465489.1 CDS rsd NC_009801.1 4533358 4533834 R binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor complement(4533358..4533834) Escherichia coli E24377A 5587886 YP_001465490.1 CDS nudC NC_009801.1 4533929 4534702 D can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4533929..4534702 Escherichia coli E24377A 5586636 YP_001465491.1 CDS EcE24377A_4538 NC_009801.1 4534625 4534726 R identified by glimmer; hypothetical protein complement(4534625..4534726) Escherichia coli E24377A 5588718 YP_001465492.1 CDS hemE NC_009801.1 4534742 4535806 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4534742..4535806 Escherichia coli E24377A 5588505 YP_001465493.1 CDS nfi NC_009801.1 4535816 4536487 D Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4535816..4536487 Escherichia coli E24377A 5586902 YP_001465494.1 CDS EcE24377A_4542 NC_009801.1 4536530 4537120 D identified by match to protein family HMM PF04222; hypothetical protein 4536530..4537120 Escherichia coli E24377A 5590323 YP_001465495.1 CDS hupA NC_009801.1 4537307 4537579 D histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4537307..4537579 Escherichia coli E24377A 5589742 YP_001465496.1 CDS EcE24377A_4544 NC_009801.1 4537592 4538287 D identified by match to protein family HMM PF07356; hypothetical protein 4537592..4538287 Escherichia coli E24377A 5586075 YP_001465497.1 CDS zraP NC_009801.1 4538289 4538714 R identified by similarity to SP:P0AAA9; zinc resistance protein complement(4538289..4538714) Escherichia coli E24377A 5590227 YP_001465498.1 CDS EcE24377A_4546 NC_009801.1 4538717 4538845 R identified by glimmer; hypothetical protein complement(4538717..4538845) Escherichia coli E24377A 5586058 YP_001465499.1 CDS zraS NC_009801.1 4538952 4540328 D identified by similarity to SP:P14377; match to protein family HMM PF00512; match to protein family HMM PF02518; sensor protein ZraS 4538952..4540328 Escherichia coli E24377A 5588758 YP_001465500.1 CDS EcE24377A_4549 NC_009801.1 4540325 4541650 D DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4540325..4541650 Escherichia coli E24377A 5589970 YP_001465501.1 CDS purD NC_009801.1 4541647 4542936 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(4541647..4542936) Escherichia coli E24377A 5590010 YP_001465502.1 CDS purH NC_009801.1 4542948 4544537 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(4542948..4544537) Escherichia coli E24377A 5588057 YP_001465503.1 CDS EcE24377A_4551 NC_009801.1 4544655 4544777 D identified by glimmer; hypothetical protein 4544655..4544777 Escherichia coli E24377A 5590420 YP_001465504.1 CDS EcE24377A_4554 NC_009801.1 4550279 4550722 R identified by match to protein family HMM PF00583; hypothetical protein complement(4550279..4550722) Escherichia coli E24377A 5587134 YP_001465505.1 CDS metA NC_009801.1 4550879 4551808 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4550879..4551808 Escherichia coli E24377A 5586756 YP_001465506.1 CDS aceB NC_009801.1 4552077 4553678 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4552077..4553678 Escherichia coli E24377A 5590326 YP_001465507.1 CDS aceA NC_009801.1 4553708 4555012 D identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346; isocitrate lyase 4553708..4555012 Escherichia coli E24377A 5586010 YP_001465508.1 CDS EcE24377A_4559 NC_009801.1 4555081 4555317 D identified by glimmer; hypothetical protein 4555081..4555317 Escherichia coli E24377A 5586505 YP_001465509.1 CDS aceK NC_009801.1 4555293 4557029 D catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase 4555293..4557029 Escherichia coli E24377A 5590658 YP_001465510.1 CDS arpA NC_009801.1 4556998 4558572 R identified by match to protein family HMM PF07906; ankyrin repeat-containing protein complement(4556998..4558572) Escherichia coli E24377A 5587800 YP_001465511.1 CDS iclR NC_009801.1 4558890 4559714 R regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator complement(4558890..4559714) Escherichia coli E24377A 5586782 YP_001465512.1 CDS metH NC_009801.1 4559914 4563597 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4559914..4563597 Escherichia coli E24377A 5588461 YP_001465513.1 CDS pNaS NC_009801.1 4563817 4565448 D identified by match to protein family HMM PF02690; match to protein family HMM TIGR00704; match to protein family HMM TIGR01013; inorganic phosphate transporter sodium-dependent 4563817..4565448 Escherichia coli E24377A 5586892 YP_001465514.1 CDS pepE NC_009801.1 4565539 4566228 R alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E complement(4565539..4566228) Escherichia coli E24377A 5586146 YP_001465515.1 CDS rluF NC_009801.1 4566440 4567312 D catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4566440..4567312 Escherichia coli E24377A 5589735 YP_001465516.1 CDS EcE24377A_4567 NC_009801.1 4567313 4567585 R identified by similarity to GB:AAZ90700.1; hypothetical protein complement(4567313..4567585) Escherichia coli E24377A 5589324 YP_001465517.1 CDS EcE24377A_4568 NC_009801.1 4567830 4567991 D identified by glimmer; hypothetical protein 4567830..4567991 Escherichia coli E24377A 5586240 YP_001465518.1 CDS EcE24377A_4569 NC_009801.1 4568115 4569242 D identified by match to protein family HMM PF01145; hypothetical protein 4568115..4569242 Escherichia coli E24377A 5586192 YP_001465519.1 CDS EcE24377A_4570 NC_009801.1 4569275 4570039 D identified by similarity to GB:CAD13753.1; hypothetical protein 4569275..4570039 Escherichia coli E24377A 5586634 YP_001465520.1 CDS EcE24377A_4571 NC_009801.1 4570075 4571001 R identified by match to protein family HMM PF06414; zeta toxin complement(4570075..4571001) Escherichia coli E24377A 5587939 YP_001465521.1 CDS lysC NC_009801.1 4571146 4572495 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase complement(4571146..4572495) Escherichia coli E24377A 5588331 YP_001465522.1 CDS pgi NC_009801.1 4573020 4574669 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4573020..4574669 Escherichia coli E24377A 5590015 YP_001465524.1 CDS EcE24377A_4575 NC_009801.1 4575350 4576018 D hypothetical protein 4575350..4576018 Escherichia coli E24377A 5587020 YP_001465525.1 CDS EcE24377A_4576 NC_009801.1 4576015 4576752 D identified by match to protein family HMM PF06251; hypothetical protein 4576015..4576752 Escherichia coli E24377A 5586329 YP_001465526.1 CDS EcE24377A_4577 NC_009801.1 4576752 4578848 D identified by match to protein family HMM PF06082; lipoprotein 4576752..4578848 Escherichia coli E24377A 5587680 YP_001465527.1 CDS EcE24377A_4579 NC_009801.1 4578852 4579013 D identified by glimmer; hypothetical protein 4578852..4579013 Escherichia coli E24377A 5588813 YP_001465528.1 CDS EcE24377A_4578 NC_009801.1 4578895 4579173 R identified by similarity to GB:ABB68492.1; hypothetical protein complement(4578895..4579173) Escherichia coli E24377A 5587842 YP_001465529.1 CDS EcE24377A_4580 NC_009801.1 4579174 4579317 D identified by glimmer; hypothetical protein 4579174..4579317 Escherichia coli E24377A 5586875 YP_001465530.1 CDS psiE NC_009801.1 4579443 4579853 D identified by match to protein family HMM PF06146; phosphate-starvation-inducible protein PsiE 4579443..4579853 Escherichia coli E24377A 5587025 YP_001465531.1 CDS xylE NC_009801.1 4579897 4581372 R xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter; D-xylose transporter XylE complement(4579897..4581372) Escherichia coli E24377A 5586709 YP_001465532.1 CDS malG NC_009801.1 4581744 4582634 R with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease complement(4581744..4582634) Escherichia coli E24377A 5587258 YP_001465533.1 CDS malF NC_009801.1 4582649 4584193 R with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein complement(4582649..4584193) Escherichia coli E24377A 5586830 YP_001465534.1 CDS EcE24377A_4585 NC_009801.1 4584183 4584305 D identified by glimmer; hypothetical protein 4584183..4584305 Escherichia coli E24377A 5589453 YP_001465535.1 CDS malE NC_009801.1 4584347 4585537 R functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein complement(4584347..4585537) Escherichia coli E24377A 5587010 YP_001465536.1 CDS malK NC_009801.1 4585902 4587017 D with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4585902..4587017 Escherichia coli E24377A 5590074 YP_001465537.1 CDS lamB NC_009801.1 4587089 4588429 D porin involved in the transport of maltose and maltodextrins; maltoporin 4587089..4588429 Escherichia coli E24377A 5586483 YP_001465538.1 CDS malM NC_009801.1 4588581 4589501 D identified by match to protein family HMM PF07148; maltose regulon periplasmic protein 4588581..4589501 Escherichia coli E24377A 5587911 YP_001465539.1 CDS EcE24377A_4589 NC_009801.1 4589476 4589628 R identified by glimmer; hypothetical protein complement(4589476..4589628) Escherichia coli E24377A 5585991 YP_001465540.1 CDS ubiC NC_009801.1 4591532 4592029 D catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4591532..4592029 Escherichia coli E24377A 5587370 YP_001465541.1 CDS ubiA NC_009801.1 4592042 4592914 D catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4592042..4592914 Escherichia coli E24377A 5586134 YP_001465542.1 CDS plsB NC_009801.1 4593069 4595492 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(4593069..4595492) Escherichia coli E24377A 5589291 YP_001465543.1 CDS dgkA NC_009801.1 4595663 4596031 D identified by similarity to SP:P0ABN1; match to protein family HMM PF01219; diacylglycerol kinase 4595663..4596031 Escherichia coli E24377A 5588569 YP_001465544.1 CDS lexA NC_009801.1 4596141 4596749 D Represses a number of genes involved in the response to DNA damage; LexA repressor 4596141..4596749 Escherichia coli E24377A 5586165 YP_001465545.1 CDS dinF NC_009801.1 4596768 4598147 D identified by similarity to SP:P28303; match to protein family HMM PF01554; match to protein family HMM TIGR00797; DNA-damage-inducible SOS response protein 4596768..4598147 Escherichia coli E24377A 5587556 YP_001465546.1 CDS EcE24377A_4598 NC_009801.1 4598263 4598472 D unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; stress-response protein 4598263..4598472 Escherichia coli E24377A 5587053 YP_001465547.1 CDS zur NC_009801.1 4598514 4599029 R Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor complement(4598514..4599029) Escherichia coli E24377A 5590631 YP_001465548.1 CDS EcE24377A_4600 NC_009801.1 4599347 4600369 D hypothetical protein 4599347..4600369 Escherichia coli E24377A 5588721 YP_001465549.1 CDS dusA NC_009801.1 4600727 4601770 D identified by similarity to SP:P32695; match to protein family HMM PF01207; match to protein family HMM TIGR00742; tRNA-dihydrouridine synthase A 4600727..4601770 Escherichia coli E24377A 5586878 YP_001465550.1 CDS pspG NC_009801.1 4601904 4602146 D coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4601904..4602146 Escherichia coli E24377A 5589636 YP_001465551.1 CDS qor NC_009801.1 4602312 4603295 R identified by similarity to SP:P28304; match to protein family HMM PF00107; match to protein family HMM PF08240; quinone oxidoreductase complement(4602312..4603295) Escherichia coli E24377A 5588200 YP_001465552.1 CDS dnaB NC_009801.1 4603378 4604793 D unwinds double stranded DNA; replicative DNA helicase 4603378..4604793 Escherichia coli E24377A 5589268 YP_001465553.1 CDS alr NC_009801.1 4604846 4605925 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4604846..4605925 Escherichia coli E24377A 5588732 YP_001465554.1 CDS tyrB NC_009801.1 4606178 4607371 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4606178..4607371 Escherichia coli E24377A 5589525 YP_001465555.1 CDS aphA NC_009801.1 4608498 4609211 D Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4608498..4609211 Escherichia coli E24377A 5587301 YP_001465556.1 CDS EcE24377A_4608 NC_009801.1 4609322 4609738 D identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149; hypothetical protein 4609322..4609738 Escherichia coli E24377A 5587040 YP_001465557.1 CDS EcE24377A_4609 NC_009801.1 4609742 4610098 D identified by match to protein family HMM PF04237; hypothetical protein 4609742..4610098 Escherichia coli E24377A 5588474 YP_001465558.1 CDS uvrA NC_009801.1 4610133 4612955 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(4610133..4612955) Escherichia coli E24377A 5587828 YP_001465559.1 CDS ssb NC_009801.1 4613209 4613745 D binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4613209..4613745 Escherichia coli E24377A 5586396 YP_001465560.1 CDS EcE24377A_4613 NC_009801.1 4613785 4613880 D identified by glimmer; hypothetical protein 4613785..4613880 Escherichia coli E24377A 5587292 YP_001465561.1 CDS EcE24377A_4612 NC_009801.1 4613844 4614125 R hypothetical protein complement(4613844..4614125) Escherichia coli E24377A 5588338 YP_001465562.1 CDS EcE24377A_4614 NC_009801.1 4614555 4616141 D identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase domain-containing protein 4614555..4616141 Escherichia coli E24377A 5587813 YP_001465563.1 CDS soxS NC_009801.1 4616144 4616467 R regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS complement(4616144..4616467) Escherichia coli E24377A 5589514 YP_001465564.1 CDS soxR NC_009801.1 4616553 4617017 D identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR01950; redox-sensitive transcriptional activator SoxR 4616553..4617017 Escherichia coli E24377A 5587103 YP_001465565.1 CDS EcE24377A_4617 NC_009801.1 4617220 4617333 R identified by glimmer; hypothetical protein complement(4617220..4617333) Escherichia coli E24377A 5586691 YP_001465566.1 CDS EcE24377A_4618 NC_009801.1 4617308 4617526 R identified by glimmer; hypothetical protein complement(4617308..4617526) Escherichia coli E24377A 5587688 YP_001465567.1 CDS EcE24377A_4619 NC_009801.1 4617563 4618912 D identified by match to protein family HMM PF00860; match to protein family HMM PF00916; sulfate permease inorganic anion transporter 4617563..4618912 Escherichia coli E24377A 5589014 YP_001465568.1 CDS EcE24377A_4620 NC_009801.1 4619063 4620712 D identified by match to protein family HMM PF00999; match to protein family HMM TIGR00831; Na+/H+ antiporter 4619063..4620712 Escherichia coli E24377A 5587217 YP_001465569.1 CDS EcE24377A_4621 NC_009801.1 4620866 4622158 R identified by match to protein family HMM PF00805; pentapeptide repeat-containing protein complement(4620866..4622158) Escherichia coli E24377A 5590413 YP_001465570.1 CDS actP NC_009801.1 4622336 4623985 R member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease complement(4622336..4623985) Escherichia coli E24377A 5588674 YP_001465571.1 CDS EcE24377A_4623 NC_009801.1 4623982 4624296 R identified by match to protein family HMM PF04341; hypothetical protein complement(4623982..4624296) Escherichia coli E24377A 5586175 YP_001465572.1 CDS EcE24377A_4624 NC_009801.1 4624296 4624424 R identified by glimmer; hypothetical protein complement(4624296..4624424) Escherichia coli E24377A 5589892 YP_001465573.1 CDS acsA NC_009801.1 4624496 4626454 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(4624496..4626454) Escherichia coli E24377A 5587364 YP_001465574.1 CDS nrfA NC_009801.1 4626846 4628282 D catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4626846..4628282 Escherichia coli E24377A 5586873 YP_001465575.1 CDS nrfB NC_009801.1 4628327 4628893 D part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4628327..4628893 Escherichia coli E24377A 5586746 YP_001465576.1 CDS nrfC NC_009801.1 4628890 4629561 D identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409; match to protein family HMM TIGR03149; cytochrome c nitrite reductase, Fe-S protein 4628890..4629561 Escherichia coli E24377A 5586157 YP_001465577.1 CDS nrfD NC_009801.1 4629558 4630514 D identified by match to protein family HMM PF03916; match to protein family HMM TIGR03148; nrfD protein 4629558..4630514 Escherichia coli E24377A 5588917 YP_001465578.1 CDS nrfE NC_009801.1 4630594 4632252 D with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4630594..4632252 Escherichia coli E24377A 5589257 YP_001465579.1 CDS nrfF NC_009801.1 4632245 4632628 D identified by similarity to SP:P32711; match to protein family HMM PF03918; match to protein family HMM TIGR03147; formate-dependent nitrite reductase complex subunit NrfF 4632245..4632628 Escherichia coli E24377A 5586388 YP_001465580.1 CDS nrfG NC_009801.1 4632625 4633221 D identified by similarity to SP:P32712; match to protein family HMM PF00515; match to protein family HMM PF07719; formate-dependent nitrite reductase complex subunit NrfG 4632625..4633221 Escherichia coli E24377A 5586416 YP_001465581.1 CDS gltP NC_009801.1 4633563 4634876 D carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4633563..4634876 Escherichia coli E24377A 5587047 YP_001465582.1 CDS EcE24377A_4634 NC_009801.1 4634954 4635643 R identified by match to protein family HMM PF08238; Sel1 repeat-containing protein complement(4634954..4635643) Escherichia coli E24377A 5586548 YP_001465583.1 CDS fdhF NC_009801.1 4635737 4637416 R identified by similarity to SP:P07658; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01591; formate dehydrogenase H subunit alpha, selenocysteine-containing complement(4635737..4637416) Escherichia coli E24377A 5588182 YP_001465584.1 CDS EcE24377A_4637 NC_009801.1 4638082 4639548 R part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP complement(4638082..4639548) Escherichia coli E24377A 5586028 YP_001465585.1 CDS mdtO NC_009801.1 4639545 4641596 R possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO complement(4639545..4641596) Escherichia coli E24377A 5585952 YP_001465586.1 CDS mdtN NC_009801.1 4641596 4642627 R with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN complement(4641596..4642627) Escherichia coli E24377A 5587461 YP_001465587.1 CDS EcE24377A_4640 NC_009801.1 4642646 4642969 R hypothetical protein complement(4642646..4642969) Escherichia coli E24377A 5586149 YP_001465588.1 CDS EcE24377A_4641 NC_009801.1 4643130 4645115 R identified by match to protein family HMM PF00753; metallo-beta-lactamase superfamily protein complement(4643130..4645115) Escherichia coli E24377A 5589993 YP_001465589.1 CDS EcE24377A_4642 NC_009801.1 4645309 4645476 D identified by glimmer; hypothetical protein 4645309..4645476 Escherichia coli E24377A 5589959 YP_001465590.1 CDS EcE24377A_4645 NC_009801.1 4645754 4646083 D identified by similarity to GB:AAZ90762.1; hypothetical protein 4645754..4646083 Escherichia coli E24377A 5588288 YP_001465591.1 CDS phnP NC_009801.1 4646230 4646988 R required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein complement(4646230..4646988) Escherichia coli E24377A 5589617 YP_001465592.1 CDS EcE24377A_4647 NC_009801.1 4646990 4647424 R PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase complement(4646990..4647424) Escherichia coli E24377A 5587488 YP_001465593.1 CDS phnN NC_009801.1 4647411 4647968 R identified by match to protein family HMM TIGR02322; ribose 1,5-bisphosphokinase complement(4647411..4647968) Escherichia coli E24377A 5586939 YP_001465594.1 CDS phnM NC_009801.1 4647968 4649104 R identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR02318; phosphonate metabolism protein PhnM complement(4647968..4649104) Escherichia coli E24377A 5587525 YP_001465595.1 CDS phnL NC_009801.1 4649101 4649781 R identified by similarity to SP:P16679; match to protein family HMM PF00005; match to protein family HMM TIGR02324; phosphonate C-P lyase system protein PhnL complement(4649101..4649781) Escherichia coli E24377A 5586490 YP_001465596.1 CDS phnK NC_009801.1 4649892 4650650 R identified by match to protein family HMM PF00005; match to protein family HMM TIGR02323; phosphonate C-P lyase system protein PhnK complement(4649892..4650650) Escherichia coli E24377A 5590141 YP_001465597.1 CDS phnJ NC_009801.1 4650647 4651492 R identified by match to protein family HMM PF06007; phosphonate metabolism protein PhnJ complement(4650647..4651492) Escherichia coli E24377A 5586432 YP_001465598.1 CDS phnI NC_009801.1 4651485 4652549 R identified by match to protein family HMM PF05861; phosphonate metabolism protein PhnI complement(4651485..4652549) Escherichia coli E24377A 5585951 YP_001465599.1 CDS phnH NC_009801.1 4652549 4653133 R identified by match to protein family HMM PF05845; carbon-phosphorus lyase complex subunit complement(4652549..4653133) Escherichia coli E24377A 5589164 YP_001465600.1 CDS phnG NC_009801.1 4653130 4653582 R identified by match to protein family HMM PF06754; match to protein family HMM TIGR03293; phosphonate C-P lyase system protein PhnG complement(4653130..4653582) Escherichia coli E24377A 5589220 YP_001465601.1 CDS phnF NC_009801.1 4653583 4654308 R may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF complement(4653583..4654308) Escherichia coli E24377A 5586384 YP_001465602.1 CDS phnE NC_009801.1 4654329 4655108 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01097; phosphonate ABC transporter permease complement(4654329..4655108) Escherichia coli E24377A 5585925 YP_001465603.1 CDS phnD NC_009801.1 4655233 4656249 R identified by match to protein family HMM TIGR01098; match to protein family HMM TIGR03431; phosphonate ABC transporter periplasmic phosphonate-binding protein complement(4655233..4656249) Escherichia coli E24377A 5589008 YP_001465604.1 CDS phnC NC_009801.1 4656274 4657062 R identified by match to protein family HMM PF00005; match to protein family HMM TIGR02315; phosphonate/organophosphate ester transporter subunit complement(4656274..4657062) Escherichia coli E24377A 5590869 YP_001465605.1 CDS EcE24377A_4660 NC_009801.1 4657000 4657110 D identified by glimmer; hypothetical protein 4657000..4657110 Escherichia coli E24377A 5586044 YP_001465606.1 CDS EcE24377A_4661 NC_009801.1 4657195 4657638 R identified by similarity to SP:P16681; match to protein family HMM PF00903; hypothetical protein complement(4657195..4657638) Escherichia coli E24377A 5586068 YP_001465607.1 CDS phnA NC_009801.1 4657798 4658133 R identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686; hypothetical protein complement(4657798..4658133) Escherichia coli E24377A 5588431 YP_001465608.1 CDS EcE24377A_4663 NC_009801.1 4658535 4660763 D hypothetical protein 4658535..4660763 Escherichia coli E24377A 5586478 YP_001465609.1 CDS EcE24377A_4664 NC_009801.1 4660793 4661638 D hypothetical protein 4660793..4661638 Escherichia coli E24377A 5588618 YP_001465610.1 CDS proP NC_009801.1 4661902 4663404 D identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM PF08946; match to protein family HMM TIGR00883; proline/glycine betaine transporter 4661902..4663404 Escherichia coli E24377A 5588284 YP_001465611.1 CDS basS NC_009801.1 4663581 4664672 R identified by similarity to SP:P30844; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor protein BasS/PmrB complement(4663581..4664672) Escherichia coli E24377A 5588987 YP_001465612.1 CDS basR NC_009801.1 4664682 4665350 R response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR complement(4664682..4665350) Escherichia coli E24377A 5585917 YP_001465613.1 CDS EcE24377A_4668 NC_009801.1 4665347 4667020 R with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein complement(4665347..4667020) Escherichia coli E24377A 5589907 YP_001465614.1 CDS adiC NC_009801.1 4667094 4668431 R identified by similarity to SP:P60061; match to protein family HMM PF00324; arginine:agmatin antiporter complement(4667094..4668431) Escherichia coli E24377A 5586074 YP_001465615.1 CDS adiY NC_009801.1 4668568 4669329 R identified by similarity to GB:AAB18143.1; match to protein family HMM PF00165; transcriptional regulator AdiY complement(4668568..4669329) Escherichia coli E24377A 5586706 YP_001465616.1 CDS adiA NC_009801.1 4669654 4671924 R identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; biodegradative arginine decarboxylase complement(4669654..4671924) Escherichia coli E24377A 5588864 YP_001465617.1 CDS melR NC_009801.1 4672120 4673028 R identified by similarity to SP:P0ACH8; match to protein family HMM PF00165; DNA-binding transcriptional regulator MelR complement(4672120..4673028) Escherichia coli E24377A 5586541 YP_001465618.1 CDS melA NC_009801.1 4673311 4674666 D identified by similarity to SP:P06720; match to protein family HMM PF02056; alpha-galactosidase 4673311..4674666 Escherichia coli E24377A 5590121 YP_001465619.1 CDS melB NC_009801.1 4674769 4676190 D identified by similarity to SP:P02921; match to protein family HMM TIGR00792; melibiose:sodium symporter 4674769..4676190 Escherichia coli E24377A 5589204 YP_001465620.1 CDS EcE24377A_4675 NC_009801.1 4676329 4676958 R hypothetical protein complement(4676329..4676958) Escherichia coli E24377A 5588663 YP_001465621.1 CDS fumB NC_009801.1 4677081 4678727 R identified by similarity to SP:P14407; match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723; fumarate hydratase complement(4677081..4678727) Escherichia coli E24377A 5590873 YP_001465622.1 CDS dcuR NC_009801.1 4680716 4681435 R response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR complement(4680716..4681435) Escherichia coli E24377A 5588082 YP_001465623.1 CDS dcuS NC_009801.1 4681432 4683063 R C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS complement(4681432..4683063) Escherichia coli E24377A 5590515 YP_001465624.1 CDS EcE24377A_4680 NC_009801.1 4683244 4683474 D identified by match to protein family HMM PF06902; hypothetical protein 4683244..4683474 Escherichia coli E24377A 5586361 YP_001465625.1 CDS EcE24377A_4681 NC_009801.1 4683486 4683758 D hypothetical protein 4683486..4683758 Escherichia coli E24377A 5590551 YP_001465626.1 CDS EcE24377A_4682 NC_009801.1 4683985 4684281 D identified by glimmer; hypothetical protein 4683985..4684281 Escherichia coli E24377A 5586524 YP_001465627.1 CDS EcE24377A_4683 NC_009801.1 4684309 4684482 D identified by similarity to GB:AAV77221.1; hypothetical protein 4684309..4684482 Escherichia coli E24377A 5587382 YP_001465628.1 CDS lysS2 NC_009801.1 4684601 4686118 R class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(4684601..4686118) Escherichia coli E24377A 5590829 YP_001465629.1 CDS EcE24377A_4685 NC_009801.1 4686355 4687812 R identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; amino acid/peptide transporter complement(4686355..4687812) Escherichia coli E24377A 5589283 YP_001465630.1 CDS EcE24377A_4686 NC_009801.1 4687871 4690018 R identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; lysine decarboxylase-like protein, constitutive complement(4687871..4690018) Escherichia coli E24377A 5590562 YP_001465631.1 CDS cadB NC_009801.1 4690098 4691432 R antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter complement(4690098..4691432) Escherichia coli E24377A 5588715 YP_001465632.1 CDS cadC NC_009801.1 4691798 4693336 R regulates the cadBA operon; DNA-binding transcriptional activator CadC complement(4691798..4693336) Escherichia coli E24377A 5587535 YP_001465633.1 CDS EcE24377A_4690 NC_009801.1 4694135 4694710 R identified by match to protein family HMM PF00440; transcriptional regulator complement(4694135..4694710) Escherichia coli E24377A 5588355 YP_001465634.1 CDS dipZ NC_009801.1 4694747 4696444 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein complement(4694747..4696444) Escherichia coli E24377A 5589721 YP_001465635.1 CDS cutA NC_009801.1 4696420 4696758 R copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA complement(4696420..4696758) Escherichia coli E24377A 5586008 YP_001465636.1 CDS dcuA NC_009801.1 4696874 4698175 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(4696874..4698175) Escherichia coli E24377A 5589624 YP_001465637.1 CDS aspA NC_009801.1 4698293 4699729 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(4698293..4699729) Escherichia coli E24377A 5589999 YP_001465638.1 CDS fxsA NC_009801.1 4700066 4700542 D F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4700066..4700542 Escherichia coli E24377A 5590768 YP_001465639.1 CDS EcE24377A_4696 NC_009801.1 4700558 4701814 R uncharacterized member of the APC superfamily of amino acid transporters; unknown function; hypothetical protein complement(4700558..4701814) Escherichia coli E24377A 5586029 YP_001465640.1 CDS groES NC_009801.1 4702090 4702383 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4702090..4702383 Escherichia coli E24377A 5588592 YP_001465641.1 CDS groEL NC_009801.1 4702427 4704073 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 4702427..4704073 Escherichia coli E24377A 5587547 YP_001465642.1 CDS EcE24377A_4699 NC_009801.1 4704211 4704564 D lipoprotein 4704211..4704564 Escherichia coli E24377A 5586590 YP_001465643.1 CDS EcE24377A_4700 NC_009801.1 4704817 4705797 D identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 4704817..4705797 Escherichia coli E24377A 5588554 YP_001465644.1 CDS EcE24377A_4701 NC_009801.1 4706046 4706915 R hypothetical protein complement(4706046..4706915) Escherichia coli E24377A 5587132 YP_001465645.1 CDS EcE24377A_4702 NC_009801.1 4707142 4707279 R identified by glimmer; hypothetical protein complement(4707142..4707279) Escherichia coli E24377A 5590434 YP_001465646.1 CDS EcE24377A_4703 NC_009801.1 4707310 4708338 R identified by match to protein family HMM PF04055; match to protein family HMM TIGR00238; KamA family protein complement(4707310..4708338) Escherichia coli E24377A 5586771 YP_001465647.1 CDS efp NC_009801.1 4708380 4708946 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4708380..4708946 Escherichia coli E24377A 5590233 YP_001465648.1 CDS ecnB NC_009801.1 4708998 4709123 D acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4708998..4709123 Escherichia coli E24377A 5588503 YP_001465649.1 CDS EcE24377A_4706 NC_009801.1 4709218 4709469 R identified by glimmer; hypothetical protein complement(4709218..4709469) Escherichia coli E24377A 5588809 YP_001465650.1 CDS sugE NC_009801.1 4709555 4709872 D member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 4709555..4709872 Escherichia coli E24377A 5589123 YP_001465651.1 CDS blc NC_009801.1 4709869 4710402 R lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc complement(4709869..4710402) Escherichia coli E24377A 5589362 YP_001465652.1 CDS ampC NC_009801.1 4710491 4711624 R identified by match to protein family HMM PF00144; beta-lactamase complement(4710491..4711624) Escherichia coli E24377A 5587513 YP_001465653.1 CDS frdD NC_009801.1 4711687 4712046 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(4711687..4712046) Escherichia coli E24377A 5587425 YP_001465654.1 CDS frdC NC_009801.1 4712057 4712452 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(4712057..4712452) Escherichia coli E24377A 5589906 YP_001465655.1 CDS frdB NC_009801.1 4712463 4713197 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(4712463..4713197) Escherichia coli E24377A 5589776 YP_001465656.1 CDS frdA NC_009801.1 4713190 4714998 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(4713190..4714998) Escherichia coli E24377A 5590072 YP_001465657.1 CDS genX NC_009801.1 4715323 4716300 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4715323..4716300 Escherichia coli E24377A 5586570 YP_001465658.1 CDS EcE24377A_4715 NC_009801.1 4716519 4718021 D identified by match to protein family HMM PF00324; amino acid permease 4716519..4718021 Escherichia coli E24377A 5586261 YP_001465659.1 CDS EcE24377A_4716 NC_009801.1 4718172 4721495 R identified by match to protein family HMM PF00924; hypothetical protein complement(4718172..4721495) Escherichia coli E24377A 5590366 YP_001465660.1 CDS psd NC_009801.1 4721517 4722485 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(4721517..4722485) Escherichia coli E24377A 5587521 YP_001465661.1 CDS rsgA NC_009801.1 4722582 4723634 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(4722582..4723634) Escherichia coli E24377A 5586620 YP_001465662.1 CDS orn NC_009801.1 4723729 4724274 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4723729..4724274 Escherichia coli E24377A 5589844 YP_001465663.1 CDS EcE24377A_4723 NC_009801.1 4725053 4726192 R identified by match to protein family HMM PF00037; match to protein family HMM PF08331; match to protein family HMM TIGR00276; iron-sulfur cluster binding protein complement(4725053..4726192) Escherichia coli E24377A 5586457 YP_001465664.1 CDS EcE24377A_4724 NC_009801.1 4726191 4727738 D identified by match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197; hypothetical protein 4726191..4727738 Escherichia coli E24377A 5590045 YP_001465665.1 CDS EcE24377A_4725 NC_009801.1 4727710 4728171 D possibly involved in cell wall synthesis; ATPase 4727710..4728171 Escherichia coli E24377A 5588701 YP_001465666.1 CDS EcE24377A_4727 NC_009801.1 4728190 4729527 D identified by match to protein family HMM PF01520; N-acetylmuramoyl-L-alanine amidase 4728190..4729527 Escherichia coli E24377A 5588517 YP_001465667.1 CDS EcE24377A_4726 NC_009801.1 4729183 4729284 R identified by glimmer; hypothetical protein complement(4729183..4729284) Escherichia coli E24377A 5588931 YP_001465668.1 CDS mutL NC_009801.1 4729537 4731384 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4729537..4731384 Escherichia coli E24377A 5588560 YP_001465669.1 CDS miaA NC_009801.1 4731377 4732327 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4731377..4732327 Escherichia coli E24377A 5590276 YP_001465670.1 CDS hfq NC_009801.1 4732413 4732721 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4732413..4732721 Escherichia coli E24377A 5587681 YP_001465671.1 CDS hflX NC_009801.1 4732797 4734077 D involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 4732797..4734077 Escherichia coli E24377A 5587792 YP_001465672.1 CDS hflK NC_009801.1 4734163 4735422 D with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4734163..4735422 Escherichia coli E24377A 5589911 YP_001465673.1 CDS hflC NC_009801.1 4735425 4736429 D with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4735425..4736429 Escherichia coli E24377A 5589899 YP_001465674.1 CDS EcE24377A_4735 NC_009801.1 4736511 4736708 D hypothetical protein 4736511..4736708 Escherichia coli E24377A 5590163 YP_001465675.1 CDS EcE24377A_4734 NC_009801.1 4736681 4736785 R identified by glimmer; hypothetical protein complement(4736681..4736785) Escherichia coli E24377A 5590408 YP_001465676.1 CDS purA NC_009801.1 4736812 4738110 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4736812..4738110 Escherichia coli E24377A 5589695 YP_001465677.1 CDS nsrR NC_009801.1 4738315 4738740 D negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4738315..4738740 Escherichia coli E24377A 5588542 YP_001465678.1 CDS rnr NC_009801.1 4738779 4741220 D 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4738779..4741220 Escherichia coli E24377A 5589897 YP_001465679.1 CDS EcE24377A_4739 NC_009801.1 4741263 4741400 D identified by glimmer; hypothetical protein 4741263..4741400 Escherichia coli E24377A 5590108 YP_001465680.1 CDS EcE24377A_4740 NC_009801.1 4741400 4742131 D Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4741400..4742131 Escherichia coli E24377A 5588007 YP_001465681.1 CDS EcE24377A_4741 NC_009801.1 4742258 4742659 D identified by similarity to GB:CAD06847.1; hypothetical protein 4742258..4742659 Escherichia coli E24377A 5585920 YP_001465682.1 CDS EcE24377A_4742 NC_009801.1 4742678 4743376 D identified by match to protein family HMM PF04012; PspA/IM30 family protein 4742678..4743376 Escherichia coli E24377A 5587674 YP_001465683.1 CDS EcE24377A_4743 NC_009801.1 4743427 4744086 D hypothetical protein 4743427..4744086 Escherichia coli E24377A 5586511 YP_001465684.1 CDS EcE24377A_4744 NC_009801.1 4744104 4744502 D identified by match to protein family HMM PF03994; inner membrane protein 4744104..4744502 Escherichia coli E24377A 5589460 YP_001465685.1 CDS EcE24377A_4745 NC_009801.1 4744512 4745150 D identified by match to protein family HMM PF06693; hypothetical protein 4744512..4745150 Escherichia coli E24377A 5586908 YP_001465686.1 CDS EcE24377A_4746 NC_009801.1 4745153 4746316 D identified by match to protein family HMM PF03738; glutathionylspermidine synthase 4745153..4746316 Escherichia coli E24377A 5586286 YP_001465687.1 CDS EcE24377A_4747 NC_009801.1 4746400 4748025 D catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4746400..4748025 Escherichia coli E24377A 5590511 YP_001465688.1 CDS EcE24377A_4748 NC_009801.1 4748142 4748429 R identified by match to protein family HMM PF07338; hypothetical protein complement(4748142..4748429) Escherichia coli E24377A 5586177 YP_001465689.1 CDS EcE24377A_4749 NC_009801.1 4748566 4748994 R in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A complement(4748566..4748994) Escherichia coli E24377A 5588904 YP_001465690.1 CDS EcE24377A_4751 NC_009801.1 4749077 4749826 D YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4749077..4749826 Escherichia coli E24377A 5587089 YP_001465691.1 CDS ulaR NC_009801.1 4749823 4750578 R negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR complement(4749823..4750578) Escherichia coli E24377A 5590711 YP_001465692.1 CDS EcE24377A_4752 NC_009801.1 4750686 4751750 R identified by similarity to SP:P39300; L-ascorbate 6-phosphate lactonase complement(4750686..4751750) Escherichia coli E24377A 5589543 YP_001465693.1 CDS ulaA NC_009801.1 4752105 4753502 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4752105..4753502 Escherichia coli E24377A 5587074 YP_001465694.1 CDS ulaC NC_009801.1 4753833 4754297 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 4753833..4754297 Escherichia coli E24377A 5589231 YP_001465695.1 CDS ulaD NC_009801.1 4754311 4754961 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4754311..4754961 Escherichia coli E24377A 5590470 YP_001465696.1 CDS EcE24377A_4756 NC_009801.1 4754317 4754985 R identified by glimmer; hypothetical protein complement(4754317..4754985) Escherichia coli E24377A 5585963 YP_001465697.1 CDS ulaE NC_009801.1 4754971 4755825 D UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4754971..4755825 Escherichia coli E24377A 5590854 YP_001465698.1 CDS sgaE NC_009801.1 4755825 4756511 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4755825..4756511 Escherichia coli E24377A 5590579 YP_001465699.1 CDS EcE24377A_4760 NC_009801.1 4756640 4756915 R identified by match to protein family HMM PF07338; hypothetical protein complement(4756640..4756915) Escherichia coli E24377A 5587917 YP_001465700.1 CDS rpsF NC_009801.1 4757242 4757637 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4757242..4757637 Escherichia coli E24377A 5586285 YP_001465701.1 CDS priB NC_009801.1 4757644 4757958 D binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4757644..4757958 Escherichia coli E24377A 5587699 YP_001465702.1 CDS rpsR NC_009801.1 4757963 4758190 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4757963..4758190 Escherichia coli E24377A 5590186 YP_001465703.1 CDS rplI NC_009801.1 4758232 4758681 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4758232..4758681 Escherichia coli E24377A 5585899 YP_001465704.1 CDS EcE24377A_4765 NC_009801.1 4758793 4759764 R identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787; TRAP transporter solute receptor DctP family protein complement(4758793..4759764) Escherichia coli E24377A 5586156 YP_001465705.1 CDS EcE24377A_4766 NC_009801.1 4759817 4761118 R identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786; TRAP C4-dicarboxylate transport system permease DctM complement(4759817..4761118) Escherichia coli E24377A 5587508 YP_001465706.1 CDS EcE24377A_4767 NC_009801.1 4761658 4763739 R identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase complement(4761658..4763739) Escherichia coli E24377A 5589472 YP_001465707.1 CDS EcE24377A_4768 NC_009801.1 4763736 4765277 R identified by match to protein family HMM PF01144; CoA-transferase complement(4763736..4765277) Escherichia coli E24377A 5588004 YP_001465708.1 CDS EcE24377A_4770 NC_009801.1 4765239 4765367 D identified by glimmer; hypothetical protein 4765239..4765367 Escherichia coli E24377A 5588219 YP_001465709.1 CDS EcE24377A_4769 NC_009801.1 4765287 4766063 R identified by match to protein family HMM PF00378; enoyl-CoA hydratase complement(4765287..4766063) Escherichia coli E24377A 5590749 YP_001465710.1 CDS EcE24377A_4771 NC_009801.1 4766073 4766915 R identified by match to protein family HMM PF01261; AP endonuclease complement(4766073..4766915) Escherichia coli E24377A 5586858 YP_001465711.1 CDS EcE24377A_4772 NC_009801.1 4766925 4767716 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(4766925..4767716) Escherichia coli E24377A 5590084 YP_001465712.1 CDS EcE24377A_4773 NC_009801.1 4767926 4768564 D identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4767926..4768564 Escherichia coli E24377A 5588774 YP_001465713.1 CDS fklB NC_009801.1 4769413 4770033 D FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4769413..4770033 Escherichia coli E24377A 5586951 YP_001465714.1 CDS cycA NC_009801.1 4770342 4771754 D involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4770342..4771754 Escherichia coli E24377A 5589782 YP_001465715.1 CDS EcE24377A_4778 NC_009801.1 4771772 4772440 D identified by glimmer; hypothetical protein 4771772..4772440 Escherichia coli E24377A 5586721 YP_001465716.1 CDS EcE24377A_4777 NC_009801.1 4771799 4772461 R Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein complement(4771799..4772461) Escherichia coli E24377A 5590670 YP_001465717.1 CDS EcE24377A_4779 NC_009801.1 4772569 4773534 R identified by similarity to SP:P39314; match to protein family HMM PF00892; hypothetical protein complement(4772569..4773534) Escherichia coli E24377A 5587867 YP_001465718.1 CDS EcE24377A_4781 NC_009801.1 4773547 4773645 D identified by glimmer; hypothetical protein 4773547..4773645 Escherichia coli E24377A 5588833 YP_001465719.1 CDS EcE24377A_4780 NC_009801.1 4773642 4774502 R identified by match to protein family HMM PF01073; match to protein family HMM PF05368; NmrA family protein complement(4773642..4774502) Escherichia coli E24377A 5586817 YP_001465720.1 CDS EcE24377A_4782 NC_009801.1 4774591 4774971 D identified by match to protein family HMM PF01638; transcriptional regulator 4774591..4774971 Escherichia coli E24377A 5587955 YP_001465721.1 CDS cpdB NC_009801.1 4775100 4777043 R periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein complement(4775100..4777043) Escherichia coli E24377A 5586786 YP_001465722.1 CDS cysQ NC_009801.1 4777233 4777973 D catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4777233..4777973 Escherichia coli E24377A 5589349 YP_001465723.1 CDS EcE24377A_4784 NC_009801.1 4777963 4778520 R identified by match to protein family HMM TIGR01626; hypothetical protein complement(4777963..4778520) Escherichia coli E24377A 5589360 YP_001465724.1 CDS EcE24377A_4786 NC_009801.1 4778845 4779051 D identified by match to protein family HMM PF06526; hypothetical protein 4778845..4779051 Escherichia coli E24377A 5587498 YP_001465725.1 CDS EcE24377A_4787 NC_009801.1 4779130 4780473 R identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; transporter complement(4779130..4780473) Escherichia coli E24377A 5589428 YP_001465726.1 CDS EcE24377A_4788 NC_009801.1 4780626 4780763 R identified by glimmer; hypothetical protein complement(4780626..4780763) Escherichia coli E24377A 5589834 YP_001465727.1 CDS msrA NC_009801.1 4780796 4781434 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(4780796..4781434) Escherichia coli E24377A 5587422 YP_001465728.1 CDS EcE24377A_4790 NC_009801.1 4781640 4783373 D identified by match to protein family HMM PF01103; match to protein family HMM PF07244; OMP85 family outer membrane protein 4781640..4783373 Escherichia coli E24377A 5589783 YP_001465729.1 CDS EcE24377A_4791 NC_009801.1 4783370 4787149 D identified by match to protein family HMM PF04357; hypothetical protein 4783370..4787149 Escherichia coli E24377A 5589886 YP_001465730.1 CDS EcE24377A_4792 NC_009801.1 4787152 4787493 D identified by match to protein family HMM PF03674; hypothetical protein 4787152..4787493 Escherichia coli E24377A 5588768 YP_001465731.1 CDS chpS NC_009801.1 4787705 4787956 D part of the toxin-antitoxin ChpB-ChpS system; antitoxin ChpS 4787705..4787956 Escherichia coli E24377A 5585980 YP_001465732.1 CDS chpB NC_009801.1 4787950 4788300 D toxin of the ChpB-ChpS toxin-antitoxin system; toxin ChpB 4787950..4788300 Escherichia coli E24377A 5586800 YP_001465733.1 CDS ppa NC_009801.1 4788380 4788910 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(4788380..4788910) Escherichia coli E24377A 5586730 YP_001465734.1 CDS EcE24377A_4796 NC_009801.1 4788922 4789047 R identified by similarity to GB:AAN83745.1; hypothetical protein complement(4788922..4789047) Escherichia coli E24377A 5589015 YP_001465735.1 CDS EcE24377A_4797 NC_009801.1 4789220 4790176 D identified by match to protein family HMM PF00532; sugar ABC transporter periplasmic sugar-binding protein 4789220..4790176 Escherichia coli E24377A 5589920 YP_001465736.1 CDS EcE24377A_4798 NC_009801.1 4790316 4791818 D identified by match to protein family HMM PF00005; sugar ABC transporter ATP-binding protein 4790316..4791818 Escherichia coli E24377A 5587970 YP_001465737.1 CDS EcE24377A_4799 NC_009801.1 4791829 4792854 D identified by match to protein family HMM PF02653; sugar ABC transporter permease 4791829..4792854 Escherichia coli E24377A 5590107 YP_001465738.1 CDS EcE24377A_4800 NC_009801.1 4792841 4793836 D membrane component of a sugar ABC transporter system; ABC transporter permease 4792841..4793836 Escherichia coli E24377A 5589488 YP_001465739.1 CDS fbp NC_009801.1 4793869 4794867 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(4793869..4794867) Escherichia coli E24377A 5587064 YP_001465740.1 CDS EcE24377A_4802 NC_009801.1 4794930 4795061 D hypothetical protein 4794930..4795061 Escherichia coli E24377A 5588341 YP_001465741.1 CDS mpl NC_009801.1 4795043 4796416 D identified by similarity to SP:P37773; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01081; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4795043..4796416 Escherichia coli E24377A 5589301 YP_001465742.1 CDS yjgA NC_009801.1 4796567 4797118 R identified by match to protein family HMM PF04751; hypothetical protein complement(4796567..4797118) Escherichia coli E24377A 5590264 YP_001465743.1 CDS pmbA NC_009801.1 4797224 4798564 D protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4797224..4798564 Escherichia coli E24377A 5587661 YP_001465744.1 CDS cybC NC_009801.1 4798747 4799133 D identified by similarity to SP:P0ABE7; match to protein family HMM PF07361; soluble cytochrome b562 4798747..4799133 Escherichia coli E24377A 5588827 YP_001465745.1 CDS nrdG NC_009801.1 4799178 4799642 R activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein complement(4799178..4799642) Escherichia coli E24377A 5589452 YP_001465746.1 CDS EcE24377A_4808 NC_009801.1 4799639 4799743 R identified by glimmer; hypothetical protein complement(4799639..4799743) Escherichia coli E24377A 5587212 YP_001465747.1 CDS nrdD NC_009801.1 4799801 4801939 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(4799801..4801939) Escherichia coli E24377A 5587673 YP_001465748.1 CDS EcE24377A_4810 NC_009801.1 4802144 4802260 D identified by similarity to GB:CAD06913.1; hypothetical protein 4802144..4802260 Escherichia coli E24377A 5588450 YP_001465749.1 CDS treC NC_009801.1 4802333 4803988 R identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403; trehalose-6-phosphate hydrolase complement(4802333..4803988) Escherichia coli E24377A 5588565 YP_001465750.1 CDS treB NC_009801.1 4804038 4805456 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunit IIBC complement(4804038..4805456) Escherichia coli E24377A 5587399 YP_001465751.1 CDS treR NC_009801.1 4805578 4806525 R regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor complement(4805578..4806525) Escherichia coli E24377A 5586116 YP_001465752.1 CDS mgtA NC_009801.1 4806904 4809600 D P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4806904..4809600 Escherichia coli E24377A 5587608 YP_001465753.1 CDS EcE24377A_4815 NC_009801.1 4809828 4810808 R identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase complement(4809828..4810808) Escherichia coli E24377A 5588423 YP_001465754.1 CDS EcE24377A_4816 NC_009801.1 4811085 4811471 R identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; endoribonuclease L-PSP complement(4811085..4811471) Escherichia coli E24377A 5587506 YP_001465755.1 CDS pyrI NC_009801.1 4811544 4812005 R involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase complement(4811544..4812005) Escherichia coli E24377A 5586213 YP_001465756.1 CDS pyrB NC_009801.1 4812018 4812953 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase complement(4812018..4812953) Escherichia coli E24377A 5590325 YP_001465757.1 CDS EcE24377A_4819 NC_009801.1 4813195 4813299 R identified by glimmer; hypothetical protein complement(4813195..4813299) Escherichia coli E24377A 5586322 YP_001465758.1 CDS EcE24377A_4820 NC_009801.1 4813372 4813767 R identified by match to protein family HMM PF01042; endoribonuclease L-PSP complement(4813372..4813767) Escherichia coli E24377A 5586572 YP_001465759.1 CDS EcE24377A_4821 NC_009801.1 4813898 4814611 R identified by match to protein family HMM PF00106; oxidoreductase complement(4813898..4814611) Escherichia coli E24377A 5590476 YP_001465760.1 CDS EcE24377A_4822 NC_009801.1 4814682 4815275 D identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4814682..4815275 Escherichia coli E24377A 5589077 YP_001465761.1 CDS EcE24377A_4823 NC_009801.1 4815420 4815872 D identified by similarity to SP:P0AF97; match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 4815420..4815872 Escherichia coli E24377A 5588975 YP_001465762.1 CDS argF NC_009801.1 4817651 4818664 R catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I complement(4817651..4818664) Escherichia coli E24377A 5586475 YP_001465763.1 CDS EcE24377A_4826 NC_009801.1 4818826 4819242 D identified by similarity to PDB:1NXI_A; match to protein family HMM PF06877; hypothetical protein 4818826..4819242 Escherichia coli E24377A 5587277 YP_001465764.1 CDS EcE24377A_4827 NC_009801.1 4819288 4819791 R identified by match to protein family HMM PF00583; acetyltransferase complement(4819288..4819791) Escherichia coli E24377A 5590465 YP_001465765.1 CDS EcE24377A_4828 NC_009801.1 4819984 4821180 D identified by match to protein family HMM PF05987; hypothetical protein 4819984..4821180 Escherichia coli E24377A 5587660 YP_001465766.1 CDS valS NC_009801.1 4821236 4824091 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(4821236..4824091) Escherichia coli E24377A 5589285 YP_001465767.1 CDS holC NC_009801.1 4824091 4824534 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(4824091..4824534) Escherichia coli E24377A 5586540 YP_001465768.1 CDS EcE24377A_4831 NC_009801.1 4824619 4824852 R identified by glimmer; hypothetical protein complement(4824619..4824852) Escherichia coli E24377A 5589188 YP_001465769.1 CDS pepA NC_009801.1 4824888 4826399 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(4824888..4826399) Escherichia coli E24377A 5587041 YP_001465770.1 CDS EcE24377A_4834 NC_009801.1 4826666 4827766 D identified by match to protein family HMM PF03739; putaitve permease 4826666..4827766 Escherichia coli E24377A 5587340 YP_001465771.1 CDS EcE24377A_4835 NC_009801.1 4827766 4828848 D identified by match to protein family HMM PF03739; permease 4827766..4828848 Escherichia coli E24377A 5589447 YP_001465772.1 CDS EcE24377A_4836 NC_009801.1 4829009 4830511 R identified by match to protein family HMM PF05872; hypothetical protein complement(4829009..4830511) Escherichia coli E24377A 5587732 YP_001465773.1 CDS EcE24377A_4837 NC_009801.1 4830639 4831658 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; zinc-binding dehydrogenase oxidoreductase complement(4830639..4831658) Escherichia coli E24377A 5586102 YP_001465774.1 CDS EcE24377A_4839 NC_009801.1 4832137 4832439 D identified by glimmer; hypothetical protein 4832137..4832439 Escherichia coli E24377A 5589833 YP_001465775.1 CDS EcE24377A_4841 NC_009801.1 4833844 4835352 R identified by match to protein family HMM PF00078; match to protein family HMM PF08388; group II intron-encoded reverse transcriptase/maturase complement(4833844..4835352) Escherichia coli E24377A 5587569 YP_001465776.1 CDS EcE24377A_4843 NC_009801.1 4836438 4836764 R identified by match to protein family HMM PF01527; IS629, transposase orfA complement(4836438..4836764) Escherichia coli E24377A 5588352 YP_001465777.1 CDS EcE24377A_4844 NC_009801.1 4836939 4837232 D identified by match to protein family HMM PF01695; IS100, transposition helper protein, truncation 4836939..4837232 Escherichia coli E24377A 5587890 YP_001465778.1 CDS EcE24377A_4845 NC_009801.1 4837283 4837501 R identified by match to protein family HMM PF00440; match to protein family HMM PF02178; TetR family transcriptional regulator complement(4837283..4837501) Escherichia coli E24377A 5586402 YP_001465779.1 CDS EcE24377A_4846 NC_009801.1 4837568 4837867 D identified by match to protein family HMM PF01527; IS3, transposase orfA 4837568..4837867 Escherichia coli E24377A 5587206 YP_001465780.1 CDS EcE24377A_4847 NC_009801.1 4837864 4838730 D identified by similarity to SP:P05822; match to protein family HMM PF00665; IS3, transposase orfB 4837864..4838730 Escherichia coli E24377A 5587657 YP_001465781.1 CDS EcE24377A_4848 NC_009801.1 4838828 4838989 R identified by glimmer; hypothetical protein complement(4838828..4838989) Escherichia coli E24377A 5586273 YP_001465782.1 CDS EcE24377A_4849 NC_009801.1 4839010 4840287 R identified by similarity to GB:AAN68935.1; hypothetical protein complement(4839010..4840287) Escherichia coli E24377A 5590365 YP_001465783.1 CDS EcE24377A_4850 NC_009801.1 4840350 4842353 R identified by match to protein family HMM PF02028; match to protein family HMM TIGR00842; BCCT family transporter complement(4840350..4842353) Escherichia coli E24377A 5586870 YP_001465784.1 CDS EcE24377A_4851 NC_009801.1 4842501 4843640 R Note that the 2 orfs of the ISSd1 transposase appear to be fused in this version of the element.; identified by match to protein family HMM PF00665; match to protein family HMM PF01527; ISSd1, transposase orfA/B, fusion complement(4842501..4843640) Escherichia coli E24377A 5589272 YP_001465785.1 CDS msbB2 NC_009801.1 4843821 4844765 R Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase complement(4843821..4844765) Escherichia coli E24377A 5586834 YP_001465786.1 CDS EcE24377A_4853 NC_009801.1 4844830 4845780 R identified by match to protein family HMM PF04393; hypothetical protein complement(4844830..4845780) Escherichia coli E24377A 5588006 YP_001465787.1 CDS EcE24377A_4854 NC_009801.1 4845785 4846873 R identified by match to protein family HMM PF00534; glycoside hydrolase family protein complement(4845785..4846873) Escherichia coli E24377A 5589237 YP_001465788.1 CDS EcE24377A_4855 NC_009801.1 4846876 4847697 R identified by match to protein family HMM PF01522; polysaccharide deacetylase complement(4846876..4847697) Escherichia coli E24377A 5587078 YP_001465789.1 CDS EcE24377A_4856 NC_009801.1 4847904 4848206 D identified by match to protein family HMM PF01527; IS911, transposase orfA 4847904..4848206 Escherichia coli E24377A 5590417 YP_001465790.1 CDS EcE24377A_4858 NC_009801.1 4849294 4850802 D identified by match to protein family HMM PF00078; match to protein family HMM PF08388; group II intron-encoded reverse transcriptase/maturase 4849294..4850802 Escherichia coli E24377A 5590055 YP_001465791.1 CDS EcE24377A_4860 NC_009801.1 4851405 4852943 R identified by match to protein family HMM PF03050; IS66 family transposase complement(4851405..4852943) Escherichia coli E24377A 5590629 YP_001465792.1 CDS EcE24377A_4861 NC_009801.1 4852993 4853340 R identified by match to protein family HMM PF05717; IS66 family orf2 complement(4852993..4853340) Escherichia coli E24377A 5587323 YP_001465793.1 CDS EcE24377A_4862 NC_009801.1 4853337 4853726 R identified by match to protein family HMM PF01527; IS66 family orf1 complement(4853337..4853726) Escherichia coli E24377A 5587060 YP_001465794.1 CDS EcE24377A_4863 NC_009801.1 4853903 4854160 D identified by similarity to GB:CAG75835.1; hypothetical protein 4853903..4854160 Escherichia coli E24377A 5587662 YP_001465795.1 CDS fecE NC_009801.1 4854718 4855485 R Part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter ATP-binding subunit complement(4854718..4855485) Escherichia coli E24377A 5587357 YP_001465796.1 CDS fecD NC_009801.1 4855486 4856442 R Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter.; iron-dicitrate transporter subunit FecD complement(4855486..4856442) Escherichia coli E24377A 5586536 YP_001465797.1 CDS fecC NC_009801.1 4856439 4857437 R part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter permease subunit complement(4856439..4857437) Escherichia coli E24377A 5587369 YP_001465798.1 CDS fecB NC_009801.1 4857434 4858342 R part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+); iron-dicitrate transporter substrate-binding subunit complement(4857434..4858342) Escherichia coli E24377A 5587762 YP_001465799.1 CDS fecA NC_009801.1 4858381 4860705 R identified by similarity to SP:P13036; match to protein family HMM PF00593; match to protein family HMM PF07660; match to protein family HMM PF07715; match to protein family HMM TIGR01783; iron(III) dicitrate transport protein FecA complement(4858381..4860705) Escherichia coli E24377A 5586888 YP_001465800.1 CDS fecR NC_009801.1 4860792 4861745 R with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon; fec operon regulator FecR complement(4860792..4861745) Escherichia coli E24377A 5586956 YP_001465801.1 CDS fecI NC_009801.1 4861742 4862263 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport; RNA polymerase sigma factor FecI complement(4861742..4862263) Escherichia coli E24377A 5590850 YP_001465802.1 CDS EcE24377A_4871 NC_009801.1 4862555 4862830 D identified by match to protein family HMM PF03811; IS1, transposase orfA 4862555..4862830 Escherichia coli E24377A 5589753 YP_001465803.1 CDS EcE24377A_4873 NC_009801.1 4863780 4863890 R identified by glimmer; hypothetical protein complement(4863780..4863890) Escherichia coli E24377A 5590510 YP_001465804.1 CDS EcE24377A_4874 NC_009801.1 4864609 4864719 R IS629, transposase orfB, truncation complement(4864609..4864719) Escherichia coli E24377A 5587693 YP_001465805.1 CDS EcE24377A_4875 NC_009801.1 4864881 4864991 D identified by glimmer; hypothetical protein 4864881..4864991 Escherichia coli E24377A 5586846 YP_001465806.1 CDS EcE24377A_4876 NC_009801.1 4865007 4866380 D identified by glimmer; hypothetical protein 4865007..4866380 Escherichia coli E24377A 5590135 YP_001465807.1 CDS EcE24377A_4878 NC_009801.1 4868053 4868400 R identified by match to protein family HMM PF05717; IS66 family orf2 complement(4868053..4868400) Escherichia coli E24377A 5587265 YP_001465808.1 CDS EcE24377A_4879 NC_009801.1 4868452 4870023 R identified by match to protein family HMM PF03050; IS66 family transposase complement(4868452..4870023) Escherichia coli E24377A 5588637 YP_001465809.1 CDS EcE24377A_4880 NC_009801.1 4870043 4870390 R identified by match to protein family HMM PF05717; IS66 family orf2 complement(4870043..4870390) Escherichia coli E24377A 5587172 YP_001465810.1 CDS EcE24377A_4881 NC_009801.1 4870390 4871067 R identified by match to protein family HMM PF01527; IS66 family orf1 complement(4870390..4871067) Escherichia coli E24377A 5589690 YP_001465811.1 CDS EcE24377A_4883 NC_009801.1 4871839 4872273 R identified by similarity to GB:ABB64202.1; hypothetical protein complement(4871839..4872273) Escherichia coli E24377A 5587453 YP_001465812.1 CDS EcE24377A_4885 NC_009801.1 4872628 4873497 D identified by glimmer; hypothetical protein 4872628..4873497 Escherichia coli E24377A 5590218 YP_001465813.1 CDS EcE24377A_4884 NC_009801.1 4872922 4873491 R hypothetical protein complement(4872922..4873491) Escherichia coli E24377A 5588705 YP_001465814.1 CDS EcE24377A_4886 NC_009801.1 4874236 4874412 R identified by match to protein family HMM PF05321; hemolysin expression modulating protein complement(4874236..4874412) Escherichia coli E24377A 5587817 YP_001465815.1 CDS EcE24377A_4887 NC_009801.1 4875047 4875325 D identified by match to protein family HMM PF05930; prophage CP4-57 regulatory protein AlpA 4875047..4875325 Escherichia coli E24377A 5588278 YP_001465816.1 CDS EcE24377A_4888 NC_009801.1 4875414 4876022 D identified by similarity to GB:AAL08467.1; hypothetical protein 4875414..4876022 Escherichia coli E24377A 5588118 YP_001465817.1 CDS EcE24377A_4889 NC_009801.1 4876346 4876438 R identified by glimmer; hypothetical protein complement(4876346..4876438) Escherichia coli E24377A 5587168 YP_001465818.1 CDS EcE24377A_4890 NC_009801.1 4877208 4878125 D identified by similarity to GB:AAL08470.1; hypothetical protein 4877208..4878125 Escherichia coli E24377A 5588092 YP_001465819.1 CDS EcE24377A_4891 NC_009801.1 4878210 4879082 D identified by match to protein family HMM PF01926; GTPase 4878210..4879082 Escherichia coli E24377A 5588235 YP_001465820.1 CDS flu1 NC_009801.1 4879454 4882300 D identified by similarity to SP:P39180; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; antigen 43 4879454..4882300 Escherichia coli E24377A 5587671 YP_001465821.1 CDS EcE24377A_4893 NC_009801.1 4882335 4882529 D identified by similarity to GB:AAS76399.1; hypothetical protein 4882335..4882529 Escherichia coli E24377A 5586051 YP_001465822.1 CDS EcE24377A_4894 NC_009801.1 4882684 4883502 D identified by similarity to GB:ABB61180.1; match to protein family HMM PF06067; hypothetical protein 4882684..4883502 Escherichia coli E24377A 5588300 YP_001465823.1 CDS EcE24377A_4895 NC_009801.1 4883844 4884317 D identified by match to protein family HMM PF03230; antirestriction protein 4883844..4884317 Escherichia coli E24377A 5587028 YP_001465824.1 CDS EcE24377A_4896 NC_009801.1 4884333 4884809 D identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608; RadC family DNA repair protein 4884333..4884809 Escherichia coli E24377A 5588357 YP_001465825.1 CDS EcE24377A_4897 NC_009801.1 4884872 4885093 D identified by similarity to GB:AAP18295.1; match to protein family HMM PF06174; hypothetical protein 4884872..4885093 Escherichia coli E24377A 5587493 YP_001465826.1 CDS EcE24377A_4898 NC_009801.1 4885093 4885206 D identified by similarity to GB:ABB61176.1; hypothetical protein 4885093..4885206 Escherichia coli E24377A 5587244 YP_001465827.1 CDS EcE24377A_4899 NC_009801.1 4885256 4885624 D identified by similarity to GB:ABB61175.1; match to protein family HMM PF06154; hypothetical protein 4885256..4885624 Escherichia coli E24377A 5590729 YP_001465828.1 CDS EcE24377A_4900 NC_009801.1 4885714 4886088 D identified by match to protein family HMM PF06755; hypothetical protein 4885714..4886088 Escherichia coli E24377A 5587164 YP_001465829.1 CDS EcE24377A_4901 NC_009801.1 4886085 4886576 D identified by similarity to GB:ABB64452.1; hypothetical protein 4886085..4886576 Escherichia coli E24377A 5589202 YP_001465830.1 CDS EcE24377A_4902 NC_009801.1 4886593 4886769 D identified by similarity to GB:ABB61172.1; match to protein family HMM PF06117; hypothetical protein 4886593..4886769 Escherichia coli E24377A 5588292 YP_001465831.1 CDS EcE24377A_4903 NC_009801.1 4887680 4890571 D identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04851; type III restriction enzyme, res subunit 4887680..4890571 Escherichia coli E24377A 5586601 YP_001465832.1 CDS EcE24377A_4904 NC_009801.1 4890592 4893714 D identified by match to protein family HMM PF01555; N4/N6-methyltransferase 4890592..4893714 Escherichia coli E24377A 5586138 YP_001465833.1 CDS EcE24377A_4905 NC_009801.1 4893717 4897097 D identified by glimmer; hypothetical protein 4893717..4897097 Escherichia coli E24377A 5589225 YP_001465834.1 CDS EcE24377A_4906 NC_009801.1 4897759 4898631 R hypothetical protein complement(4897759..4898631) Escherichia coli E24377A 5589808 YP_001465835.1 CDS EcE24377A_4907 NC_009801.1 4898713 4898835 D identified by glimmer; hypothetical protein 4898713..4898835 Escherichia coli E24377A 5589451 YP_001465836.1 CDS EcE24377A_4908 NC_009801.1 4898843 4899823 R identified by match to protein family HMM PF03629; hypothetical protein complement(4898843..4899823) Escherichia coli E24377A 5587368 YP_001465837.1 CDS EcE24377A_4909 NC_009801.1 4899888 4900994 R identified by match to protein family HMM PF01344; match to protein family HMM PF07646; N-acetylneuraminic acid mutarotase complement(4899888..4900994) Escherichia coli E24377A 5589013 YP_001465838.1 CDS EcE24377A_4910 NC_009801.1 4901014 4901730 R identified by match to protein family HMM PF06178; oligogalacturonate-specific porin protein KdgM complement(4901014..4901730) Escherichia coli E24377A 5589809 YP_001465839.1 CDS EcE24377A_4911 NC_009801.1 4902395 4902532 R identified by glimmer; hypothetical protein complement(4902395..4902532) Escherichia coli E24377A 5586373 YP_001465840.1 CDS EcE24377A_4912 NC_009801.1 4903155 4903430 D identified by match to protein family HMM PF03811; IS1, transposase orfA 4903155..4903430 Escherichia coli E24377A 5588962 YP_001465841.1 CDS EcE24377A_4913 NC_009801.1 4903349 4903843 D identified by match to protein family HMM PF03400; IS1, transposase orfB 4903349..4903843 Escherichia coli E24377A 5586603 YP_001465842.1 CDS EcE24377A_4914 NC_009801.1 4903891 4904751 D identified by similarity to SP:P30130; match to protein family HMM PF00577; outer membrane usher protein FimD, truncation 4903891..4904751 Escherichia coli E24377A 5586016 YP_001465843.1 CDS fimF NC_009801.1 4904761 4905291 D identified by similarity to SP:P08189; match to protein family HMM PF00419; protein FimF 4904761..4905291 Escherichia coli E24377A 5590320 YP_001465844.1 CDS fimG NC_009801.1 4905304 4905807 D identified by similarity to SP:P08190; match to protein family HMM PF00419; protein fimG 4905304..4905807 Escherichia coli E24377A 5586017 YP_001465845.1 CDS fimH NC_009801.1 4905827 4906729 D identified by match to protein family HMM PF00419; match to protein family HMM PF09160; protein FimH 4905827..4906729 Escherichia coli E24377A 5589412 YP_001465846.1 CDS EcE24377A_4918 NC_009801.1 4906777 4906881 R identified by glimmer; hypothetical protein complement(4906777..4906881) Escherichia coli E24377A 5590722 YP_001465847.1 CDS gntP NC_009801.1 4906902 4908245 R identified by similarity to SP:P0AC94; match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791; fructuronate transporter complement(4906902..4908245) Escherichia coli E24377A 5586170 YP_001465848.1 CDS uxuA NC_009801.1 4908585 4909769 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 4908585..4909769 Escherichia coli E24377A 5588499 YP_001465849.1 CDS EcE24377A_4921 NC_009801.1 4909850 4911310 D identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol dehydrogenase 4909850..4911310 Escherichia coli E24377A 5586280 YP_001465850.1 CDS EcE24377A_4922 NC_009801.1 4911332 4911526 R identified by glimmer; hypothetical protein complement(4911332..4911526) Escherichia coli E24377A 5590292 YP_001465851.1 CDS EcE24377A_4923 NC_009801.1 4911525 4912298 D regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 4911525..4912298 Escherichia coli E24377A 5587675 YP_001465852.1 CDS EcE24377A_4924 NC_009801.1 4913788 4913931 D identified by glimmer; hypothetical protein 4913788..4913931 Escherichia coli E24377A 5588469 YP_001465853.1 CDS iraD NC_009801.1 4913900 4914289 D inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 4913900..4914289 Escherichia coli E24377A 5590870 YP_001465854.1 CDS EcE24377A_4925 NC_009801.1 4914282 4915193 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator complement(4914282..4915193) Escherichia coli E24377A 5589673 YP_001465855.1 CDS iadA NC_009801.1 4915258 4916430 R identified by similarity to SP:P39377; match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR01975; isoaspartyl dipeptidase complement(4915258..4916430) Escherichia coli E24377A 5588066 YP_001465856.1 CDS EcE24377A_4928 NC_009801.1 4916443 4916904 R identified by match to protein family HMM PF07670; hypothetical protein complement(4916443..4916904) Escherichia coli E24377A 5586503 YP_001465857.1 CDS EcE24377A_4929 NC_009801.1 4916901 4917584 R identified by match to protein family HMM PF07670; transporter complement(4916901..4917584) Escherichia coli E24377A 5589431 YP_001465858.1 CDS EcE24377A_4930 NC_009801.1 4917596 4917697 D identified by glimmer; hypothetical protein 4917596..4917697 Escherichia coli E24377A 5587856 YP_001465859.1 CDS kptA NC_009801.1 4917834 4918388 D in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown; RNA 2'-phosphotransferase-like protein 4917834..4918388 Escherichia coli E24377A 5589062 YP_001465860.1 CDS EcE24377A_4932 NC_009801.1 4918401 4919579 R identified by match to protein family HMM PF06779; match to protein family HMM PF07690; major facilitator transporter complement(4918401..4919579) Escherichia coli E24377A 5586890 YP_001465861.1 CDS EcE24377A_4933 NC_009801.1 4919647 4920618 R identified by match to protein family HMM PF06977; hypothetical protein complement(4919647..4920618) Escherichia coli E24377A 5589581 YP_001465862.1 CDS EcE24377A_4935 NC_009801.1 4920572 4920829 R hypothetical protein complement(4920572..4920829) Escherichia coli E24377A 5589547 YP_001465863.1 CDS hgdC NC_009801.1 4920826 4921593 R identified by similarity to SP:P11568; match to protein family HMM PF01869; match to protein family HMM TIGR00241; (R)-2-hydroxyglutaryl-CoA dehydratase activator complement(4920826..4921593) Escherichia coli E24377A 5588389 YP_001465864.1 CDS EcE24377A_4937 NC_009801.1 4921603 4922754 R identified by match to protein family HMM PF06050; 2-hydroxyglutaryl-CoA dehydratase subunit D complement(4921603..4922754) Escherichia coli E24377A 5586749 YP_001465865.1 CDS EcE24377A_4938 NC_009801.1 4922870 4924150 R identified by match to protein family HMM PF04286; hypothetical protein complement(4922870..4924150) Escherichia coli E24377A 5590314 YP_001465866.1 CDS mdtM NC_009801.1 4924191 4925423 R identified by match to protein family HMM PF07690; multidrug resistance protein MdtM complement(4924191..4925423) Escherichia coli E24377A 5586999 YP_001465867.1 CDS EcE24377A_4940 NC_009801.1 4925737 4926012 D identified by match to protein family HMM PF03811; IS1, transposase orfA 4925737..4926012 Escherichia coli E24377A 5589464 YP_001465868.1 CDS EcE24377A_4942 NC_009801.1 4926638 4926919 D identified by similarity to GB:BAB72712.1; match to protein family HMM PF04365; hypothetical protein 4926638..4926919 Escherichia coli E24377A 5588541 YP_001465869.1 CDS EcE24377A_4943 NC_009801.1 4926906 4927208 D identified by similarity to GB:AAV80076.1; hypothetical protein 4926906..4927208 Escherichia coli E24377A 5590783 YP_001465870.1 CDS EcE24377A_4944 NC_009801.1 4927242 4928198 R identified by match to protein family HMM PF02492; match to protein family HMM PF07683; GTP-binding protein YjiA complement(4927242..4928198) Escherichia coli E24377A 5589873 YP_001465871.1 CDS EcE24377A_4945 NC_009801.1 4928209 4928412 R identified by similarity to SP:P0ADD1; match to protein family HMM PF04328; hypothetical protein complement(4928209..4928412) Escherichia coli E24377A 5587575 YP_001465872.1 CDS EcE24377A_4946 NC_009801.1 4928462 4930627 R identified by match to protein family HMM PF02554; carbon starvation family protein complement(4928462..4930627) Escherichia coli E24377A 5586903 YP_001465873.1 CDS tsr NC_009801.1 4930989 4932653 D identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203; methyl-accepting chemotaxis protein I 4930989..4932653 Escherichia coli E24377A 5587670 YP_001465874.1 CDS EcE24377A_4948 NC_009801.1 4932702 4934063 R identified by match to protein family HMM PF07690; major facilitator transporter complement(4932702..4934063) Escherichia coli E24377A 5587458 YP_001465875.1 CDS EcE24377A_4949 NC_009801.1 4934278 4935192 R identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator complement(4934278..4935192) Escherichia coli E24377A 5587863 YP_001465876.1 CDS EcE24377A_4950 NC_009801.1 4935205 4935297 D identified by glimmer; hypothetical protein 4935205..4935297 Escherichia coli E24377A 5590709 YP_001465877.1 CDS EcE24377A_4951 NC_009801.1 4935331 4936353 D identified by match to protein family HMM PF00107; match to protein family HMM PF08240; zinc-binding dehydrogenase oxidoreductase 4935331..4936353 Escherichia coli E24377A 5586241 YP_001465878.1 CDS mdoB NC_009801.1 4936493 4938784 R catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I complement(4936493..4938784) Escherichia coli E24377A 5588948 YP_001465879.1 CDS EcE24377A_4953 NC_009801.1 4939038 4939535 R hypothetical protein complement(4939038..4939535) Escherichia coli E24377A 5588289 YP_001465880.1 CDS dnaC NC_009801.1 4939581 4940318 R acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC complement(4939581..4940318) Escherichia coli E24377A 5586665 YP_001465881.1 CDS dnaT NC_009801.1 4940321 4940860 R This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI complement(4940321..4940860) Escherichia coli E24377A 5589437 YP_001465882.2 CDS EcE24377A_4956 NC_009801.1 4940967 4941440 R hypothetical protein complement(4940967..4941440) Escherichia coli E24377A 5588124 YP_001465883.1 CDS EcE24377A_4957 NC_009801.1 4941431 4942264 R identified by match to protein family HMM PF06738; hypothetical protein complement(4941431..4942264) Escherichia coli E24377A 5589114 YP_001465884.1 CDS EcE24377A_4958 NC_009801.1 4942503 4942604 D identified by glimmer; hypothetical protein 4942503..4942604 Escherichia coli E24377A 5588377 YP_001465885.1 CDS EcE24377A_4959 NC_009801.1 4942822 4943547 D identified by match to protein family HMM PF00196; LuxR family transcriptional regulator 4942822..4943547 Escherichia coli E24377A 5587591 YP_001465886.1 CDS EcE24377A_4960 NC_009801.1 4943505 4944182 D regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 4943505..4944182 Escherichia coli E24377A 5589465 YP_001465887.1 CDS fhuF NC_009801.1 4944220 4945008 R identified by similarity to SP:P39405; match to protein family HMM PF06276; ferric hydroximate transport ferric iron reductase complement(4944220..4945008) Escherichia coli E24377A 5588550 YP_001465888.1 CDS EcE24377A_4962 NC_009801.1 4945038 4945385 D identified by similarity to GB:AAN83867.1; match to protein family HMM PF07256; hypothetical protein 4945038..4945385 Escherichia coli E24377A 5585957 YP_001465889.1 CDS rsmC NC_009801.1 4946014 4947045 R 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase complement(4946014..4947045) Escherichia coli E24377A 5588606 YP_001465890.1 CDS holD NC_009801.1 4947148 4947561 D with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 4947148..4947561 Escherichia coli E24377A 5588924 YP_001465891.1 CDS rimI NC_009801.1 4947530 4947976 D alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 4947530..4947976 Escherichia coli E24377A 5590550 YP_001465892.1 CDS yjjG NC_009801.1 4947991 4948668 D manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 4947991..4948668 Escherichia coli E24377A 5586377 YP_001465893.1 CDS EcE24377A_4969 NC_009801.1 4948495 4949985 R identified by glimmer; hypothetical protein complement(4948495..4949985) Escherichia coli E24377A 5589422 YP_001465894.1 CDS prfC NC_009801.1 4948759 4950348 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 4948759..4950348 Escherichia coli E24377A 5588985 YP_001465895.1 CDS EcE24377A_4972 NC_009801.1 4950708 4951400 R identified by glimmer; hypothetical protein complement(4950708..4951400) Escherichia coli E24377A 5588479 YP_001465896.1 CDS osmY NC_009801.1 4950741 4951346 D identified by similarity to SP:P27291; match to protein family HMM PF04972; hypothetical protein 4950741..4951346 Escherichia coli E24377A 5588698 YP_001465897.1 CDS EcE24377A_4974 NC_009801.1 4951473 4951634 D identified by glimmer; hypothetical protein 4951473..4951634 Escherichia coli E24377A 5587630 YP_001465898.1 CDS EcE24377A_4975 NC_009801.1 4951756 4952829 D identified by match to protein family HMM PF01734; patatin family phospholipase 4951756..4952829 Escherichia coli E24377A 5588929 YP_001465899.1 CDS EcE24377A_4976 NC_009801.1 4952826 4953608 D identified by match to protein family HMM PF01026; deoxyribonuclease YjjV 4952826..4953608 Escherichia coli E24377A 5590199 YP_001465900.1 CDS EcE24377A_4977 NC_009801.1 4953721 4954584 R identified by match to protein family HMM PF00037; match to protein family HMM PF04055; radical SAM domain-containing protein complement(4953721..4954584) Escherichia coli E24377A 5588163 YP_001465901.1 CDS EcE24377A_4978 NC_009801.1 4954556 4956106 R yjjI; hypothetical protein complement(4954556..4956106) Escherichia coli E24377A 5588716 YP_001465902.1 CDS EcE24377A_4979 NC_009801.1 4956082 4956207 D hypothetical protein 4956082..4956207 Escherichia coli E24377A 5590627 YP_001465903.1 CDS deoC NC_009801.1 4956364 4957143 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 4956364..4957143 Escherichia coli E24377A 5588059 YP_001465904.1 CDS deoA NC_009801.1 4957270 4958592 D Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 4957270..4958592 Escherichia coli E24377A 5588086 YP_001465905.1 CDS deoB NC_009801.1 4958644 4959867 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 4958644..4959867 Escherichia coli E24377A 5587262 YP_001465906.1 CDS deoD NC_009801.1 4959947 4960666 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 4959947..4960666 Escherichia coli E24377A 5588156 YP_001465907.1 CDS lplA NC_009801.1 4961122 4962138 R Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A complement(4961122..4962138) Escherichia coli E24377A 5589643 YP_001465908.1 CDS EcE24377A_4986 NC_009801.1 4962166 4962810 R hypothetical protein complement(4962166..4962810) Escherichia coli E24377A 5586757 YP_001465909.1 CDS serB NC_009801.1 4962916 4963884 D catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 4962916..4963884 Escherichia coli E24377A 5586621 YP_001465910.1 CDS radA NC_009801.1 4963933 4965315 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4963933..4965315 Escherichia coli E24377A 5588978 YP_001465911.1 CDS nadR NC_009801.1 4965336 4966568 D catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 4965336..4966568 Escherichia coli E24377A 5588559 YP_001465912.1 CDS EcE24377A_4990 NC_009801.1 4966875 4968542 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein complement(4966875..4968542) Escherichia coli E24377A 5586025 YP_001465913.1 CDS slt NC_009801.1 4968753 4970690 D catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 4968753..4970690 Escherichia coli E24377A 5590397 YP_001465914.1 CDS trpR NC_009801.1 4970780 4971106 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 4970780..4971106 Escherichia coli E24377A 5590440 YP_001465915.1 CDS EcE24377A_4993 NC_009801.1 4971191 4971721 R pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase complement(4971191..4971721) Escherichia coli E24377A 5586418 YP_001465916.1 CDS EcE24377A_4995 NC_009801.1 4971764 4972411 D catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 4971764..4972411 Escherichia coli E24377A 5589153 YP_001465917.1 CDS rob NC_009801.1 4972408 4973277 R identified by match to protein family HMM PF00165; match to protein family HMM PF06445; right origin-binding protein complement(4972408..4973277) Escherichia coli E24377A 5586663 YP_001465918.1 CDS EcE24377A_4996 NC_009801.1 4973488 4973961 D identified by match to protein family HMM PF05981; hypothetical protein 4973488..4973961 Escherichia coli E24377A 5587486 YP_001465919.1 CDS creB NC_009801.1 4973974 4974663 D response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 4973974..4974663 Escherichia coli E24377A 5589619 YP_001465920.1 CDS creC NC_009801.1 4974663 4976087 D part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 4974663..4976087 Escherichia coli E24377A 5587291 YP_001465921.1 CDS EcE24377A_4999 NC_009801.1 4976145 4977497 D identified by match to protein family HMM PF06123; hypothetical protein 4976145..4977497 Escherichia coli E24377A 5588100 YP_001465922.1 CDS arcA NC_009801.1 4977557 4978273 R identified by match to protein family HMM PF00072; match to protein family HMM PF00486; two-component response regulator complement(4977557..4978273) Escherichia coli E24377A 5589070 YP_001465923.1 CDS EcE24377A_5001 NC_009801.1 4978369 4978509 D identified by similarity to GB:AAV80131.1; hypothetical protein 4978369..4978509 Escherichia coli E24377A 5590436 YP_001465924.1 CDS EcE24377A_5002 NC_009801.1 4978909 4979595 D member of the SPOUT superfamily of methyltransferases; RNA methyltransferase 4978909..4979595 Escherichia coli E24377A 5589935 EcE24377A_5004 tRNA EcE24377A_5004 NC_009801.1 227242 227318 D tRNA-Ile 227242..227318 Escherichia coli E24377A 5587121 EcE24377A_5005 tRNA EcE24377A_5005 NC_009801.1 227361 227436 D tRNA-Ala 227361..227436 Escherichia coli E24377A 5590496 EcE24377A_5008 tRNA EcE24377A_5008 NC_009801.1 230927 231003 D tRNA-Asp 230927..231003 Escherichia coli E24377A 5586928 EcE24377A_5009 tRNA EcE24377A_5009 NC_009801.1 239151 239227 D tRNA-Asp 239151..239227 Escherichia coli E24377A 5589347 EcE24377A_5010 tRNA EcE24377A_5010 NC_009801.1 295502 295577 D tRNA-Thr 295502..295577 Escherichia coli E24377A 5589542 EcE24377A_5011 tRNA EcE24377A_5011 NC_009801.1 320696 320775 D tRNA-OTHER 320696..320775 Escherichia coli E24377A 5590591 EcE24377A_5012 tRNA EcE24377A_5012 NC_009801.1 381414 381494 D tRNA-OTHER 381414..381494 Escherichia coli E24377A 5590319 EcE24377A_5013 tRNA EcE24377A_5013 NC_009801.1 599636 599712 D tRNA-Arg 599636..599712 Escherichia coli E24377A 5586061 EcE24377A_5014 tRNA EcE24377A_5014 NC_009801.1 719921 719995 R tRNA-Gln complement(719921..719995) Escherichia coli E24377A 5586466 EcE24377A_5015 tRNA EcE24377A_5015 NC_009801.1 720044 720120 R tRNA-Met complement(720044..720120) Escherichia coli E24377A 5588731 EcE24377A_5016 tRNA EcE24377A_5016 NC_009801.1 720136 720210 R tRNA-Gln complement(720136..720210) Escherichia coli E24377A 5590544 EcE24377A_5017 tRNA EcE24377A_5017 NC_009801.1 720245 720319 R tRNA-Gln complement(720245..720319) Escherichia coli E24377A 5589567 EcE24377A_5018 tRNA EcE24377A_5018 NC_009801.1 720343 720427 R tRNA-Leu complement(720343..720427) Escherichia coli E24377A 5589584 EcE24377A_5019 tRNA EcE24377A_5019 NC_009801.1 720436 720512 R tRNA-Met complement(720436..720512) Escherichia coli E24377A 5587873 EcE24377A_5020 tRNA EcE24377A_5020 NC_009801.1 800448 800523 D tRNA-Lys 800448..800523 Escherichia coli E24377A 5586351 EcE24377A_5021 tRNA EcE24377A_5021 NC_009801.1 800659 800734 D tRNA-Val 800659..800734 Escherichia coli E24377A 5586023 EcE24377A_5022 tRNA EcE24377A_5022 NC_009801.1 800738 800813 D tRNA-Lys 800738..800813 Escherichia coli E24377A 5589526 EcE24377A_5023 tRNA EcE24377A_5023 NC_009801.1 800960 801035 D tRNA-Lys 800960..801035 Escherichia coli E24377A 5586048 EcE24377A_5024 tRNA EcE24377A_5024 NC_009801.1 801069 801144 D tRNA-Lys 801069..801144 Escherichia coli E24377A 5589458 EcE24377A_5025 tRNA EcE24377A_5025 NC_009801.1 975294 975381 R tRNA-Ser complement(975294..975381) Escherichia coli E24377A 5588832 EcE24377A_5026 tRNA EcE24377A_5026 NC_009801.1 1110286 1110373 R tRNA-Ser complement(1110286..1110373) Escherichia coli E24377A 5589307 EcE24377A_5027 tRNA EcE24377A_5027 NC_009801.1 1175030 1175117 R tRNA-Ser complement(1175030..1175117) Escherichia coli E24377A 5587542 EcE24377A_5028 tRNA EcE24377A_5028 NC_009801.1 1280134 1280209 D tRNA-Met 1280134..1280209 Escherichia coli E24377A 5586504 EcE24377A_5029 tRNA EcE24377A_5029 NC_009801.1 1280290 1280365 D tRNA-Thr 1280290..1280365 Escherichia coli E24377A 5586894 EcE24377A_5030 tRNA EcE24377A_5030 NC_009801.1 1280369 1280443 D tRNA-Gly 1280369..1280443 Escherichia coli E24377A 5589749 EcE24377A_5031 tRNA EcE24377A_5031 NC_009801.1 1377482 1377566 R tRNA-Tyr complement(1377482..1377566) Escherichia coli E24377A 5586742 EcE24377A_5032 tRNA EcE24377A_5032 NC_009801.1 1377600 1377684 R tRNA-Tyr complement(1377600..1377684) Escherichia coli E24377A 5590088 EcE24377A_5033 tRNA EcE24377A_5033 NC_009801.1 1437390 1437465 D tRNA-Thr 1437390..1437465 Escherichia coli E24377A 5590090 EcE24377A_5034 tRNA EcE24377A_5034 NC_009801.1 1437469 1437543 D tRNA-Gly 1437469..1437543 Escherichia coli E24377A 5590097 EcE24377A_5035 tRNA EcE24377A_5035 NC_009801.1 1872253 1872329 D tRNA-Val 1872253..1872329 Escherichia coli E24377A 5588390 EcE24377A_5036 tRNA EcE24377A_5036 NC_009801.1 1872334 1872410 D tRNA-Val 1872334..1872410 Escherichia coli E24377A 5586453 EcE24377A_5037 tRNA EcE24377A_5037 NC_009801.1 2118636 2118722 R tRNA-Leu complement(2118636..2118722) Escherichia coli E24377A 5587397 EcE24377A_5038 tRNA EcE24377A_5038 NC_009801.1 2118735 2118808 R tRNA-Cys complement(2118735..2118808) Escherichia coli E24377A 5587759 EcE24377A_5039 tRNA EcE24377A_5039 NC_009801.1 2118863 2118938 R tRNA-Gly complement(2118863..2118938) Escherichia coli E24377A 5588570 EcE24377A_5040 tRNA EcE24377A_5040 NC_009801.1 2221294 2221383 R tRNA-Ser complement(2221294..2221383) Escherichia coli E24377A 5587601 EcE24377A_5041 tRNA EcE24377A_5041 NC_009801.1 2222375 2222450 D tRNA-Asn 2222375..2222450 Escherichia coli E24377A 5587767 EcE24377A_5042 tRNA EcE24377A_5042 NC_009801.1 2235854 2235929 R tRNA-Asn complement(2235854..2235929) Escherichia coli E24377A 5585940 EcE24377A_5043 tRNA EcE24377A_5043 NC_009801.1 2237678 2237753 D tRNA-Asn 2237678..2237753 Escherichia coli E24377A 5587981 EcE24377A_5044 tRNA EcE24377A_5044 NC_009801.1 2240087 2240162 D tRNA-Asn 2240087..2240162 Escherichia coli E24377A 5588062 EcE24377A_5045 tRNA EcE24377A_5045 NC_009801.1 2474500 2474576 D tRNA-Pro 2474500..2474576 Escherichia coli E24377A 5590497 EcE24377A_5046 tRNA EcE24377A_5046 NC_009801.1 2636832 2636906 D tRNA-Arg 2636832..2636906 Escherichia coli E24377A 5589192 EcE24377A_5047 tRNA EcE24377A_5047 NC_009801.1 2680197 2680272 R tRNA-Ala complement(2680197..2680272) Escherichia coli E24377A 5588107 EcE24377A_5048 tRNA EcE24377A_5048 NC_009801.1 2680312 2680387 R tRNA-Ala complement(2680312..2680387) Escherichia coli E24377A 5589086 EcE24377A_5049 tRNA EcE24377A_5049 NC_009801.1 2683087 2683162 D tRNA-Val 2683087..2683162 Escherichia coli E24377A 5586930 EcE24377A_5050 tRNA EcE24377A_5050 NC_009801.1 2683207 2683282 D tRNA-Val 2683207..2683282 Escherichia coli E24377A 5587574 EcE24377A_5051 tRNA EcE24377A_5051 NC_009801.1 2683329 2683404 D tRNA-Val 2683329..2683404 Escherichia coli E24377A 5590316 EcE24377A_5052 tRNA EcE24377A_5052 NC_009801.1 2683409 2683484 D tRNA-Lys 2683409..2683484 Escherichia coli E24377A 5586449 EcE24377A_5055 tRNA EcE24377A_5055 NC_009801.1 2878997 2879072 R tRNA-Glu complement(2878997..2879072) Escherichia coli E24377A 5586774 EcE24377A_5058 tRNA EcE24377A_5058 NC_009801.1 2946286 2946361 R tRNA-Met complement(2946286..2946361) Escherichia coli E24377A 5590336 EcE24377A_5059 tRNA EcE24377A_5059 NC_009801.1 2978413 2978489 R tRNA-Arg complement(2978413..2978489) Escherichia coli E24377A 5588196 EcE24377A_5060 tRNA EcE24377A_5060 NC_009801.1 2978553 2978629 R tRNA-Arg complement(2978553..2978629) Escherichia coli E24377A 5589656 EcE24377A_5061 tRNA EcE24377A_5061 NC_009801.1 2978693 2978769 R tRNA-Arg complement(2978693..2978769) Escherichia coli E24377A 5586152 EcE24377A_5062 tRNA EcE24377A_5062 NC_009801.1 2978967 2979043 R tRNA-Arg complement(2978967..2979043) Escherichia coli E24377A 5586537 EcE24377A_5063 tRNA EcE24377A_5063 NC_009801.1 2979047 2979139 R tRNA-Ser complement(2979047..2979139) Escherichia coli E24377A 5585984 EcE24377A_5064 tRNA EcE24377A_5064 NC_009801.1 3127302 3127378 D tRNA-Met 3127302..3127378 Escherichia coli E24377A 5590020 EcE24377A_5065 tRNA EcE24377A_5065 NC_009801.1 3127412 3127488 D tRNA-Met 3127412..3127488 Escherichia coli E24377A 5587598 EcE24377A_5066 tRNA EcE24377A_5066 NC_009801.1 3127521 3127597 D tRNA-Met 3127521..3127597 Escherichia coli E24377A 5590879 EcE24377A_5067 tRNA EcE24377A_5067 NC_009801.1 3202626 3202699 R tRNA-Gly complement(3202626..3202699) Escherichia coli E24377A 5588384 EcE24377A_5068 tRNA EcE24377A_5068 NC_009801.1 3325510 3325585 D tRNA-Phe 3325510..3325585 Escherichia coli E24377A 5586398 EcE24377A_5069 tRNA EcE24377A_5069 NC_009801.1 3397364 3397442 D tRNA-OTHER 3397364..3397442 Escherichia coli E24377A 5588103 EcE24377A_5070 tRNA EcE24377A_5070 NC_009801.1 3545264 3545339 D tRNA-Met 3545264..3545339 Escherichia coli E24377A 5588596 EcE24377A_5071 tRNA EcE24377A_5071 NC_009801.1 3655517 3655593 R tRNA-Met complement(3655517..3655593) Escherichia coli E24377A 5586961 EcE24377A_5072 tRNA EcE24377A_5072 NC_009801.1 3659376 3659462 R tRNA-Leu complement(3659376..3659462) Escherichia coli E24377A 5586112 EcE24377A_5073 tRNA EcE24377A_5073 NC_009801.1 3753385 3753460 R tRNA-Thr complement(3753385..3753460) Escherichia coli E24377A 5587629 EcE24377A_5076 tRNA EcE24377A_5076 NC_009801.1 3756772 3756847 R tRNA-Ala complement(3756772..3756847) Escherichia coli E24377A 5590122 EcE24377A_5077 tRNA EcE24377A_5077 NC_009801.1 3756890 3756966 R tRNA-Ile complement(3756890..3756966) Escherichia coli E24377A 5589890 EcE24377A_5079 tRNA EcE24377A_5079 NC_009801.1 4022726 4022802 R tRNA-Pro complement(4022726..4022802) Escherichia coli E24377A 5586684 EcE24377A_5080 tRNA EcE24377A_5080 NC_009801.1 4152846 4152936 D tRNA-Sec 4152846..4152936 Escherichia coli E24377A 5588982 EcE24377A_5082 tRNA EcE24377A_5082 NC_009801.1 4265332 4265407 D tRNA-Glu 4265332..4265407 Escherichia coli E24377A 5586108 EcE24377A_5085 tRNA EcE24377A_5085 NC_009801.1 4268769 4268845 D tRNA-Asp 4268769..4268845 Escherichia coli E24377A 5586929 EcE24377A_5086 tRNA EcE24377A_5086 NC_009801.1 4268854 4268929 D tRNA-Trp 4268854..4268929 Escherichia coli E24377A 5589832 EcE24377A_5087 tRNA EcE24377A_5087 NC_009801.1 4304216 4304292 D tRNA-Arg 4304216..4304292 Escherichia coli E24377A 5589438 EcE24377A_5088 tRNA EcE24377A_5088 NC_009801.1 4304351 4304426 D tRNA-His 4304351..4304426 Escherichia coli E24377A 5586425 EcE24377A_5089 tRNA EcE24377A_5089 NC_009801.1 4304447 4304533 D tRNA-Leu 4304447..4304533 Escherichia coli E24377A 5586552 EcE24377A_5090 tRNA EcE24377A_5090 NC_009801.1 4304576 4304652 D tRNA-Pro 4304576..4304652 Escherichia coli E24377A 5590096 EcE24377A_5092 tRNA EcE24377A_5092 NC_009801.1 4362523 4362599 D tRNA-Ile 4362523..4362599 Escherichia coli E24377A 5586707 EcE24377A_5093 tRNA EcE24377A_5093 NC_009801.1 4362642 4362717 D tRNA-Ala 4362642..4362717 Escherichia coli E24377A 5588767 EcE24377A_5097 tRNA EcE24377A_5097 NC_009801.1 4505398 4505473 D tRNA-Glu 4505398..4505473 Escherichia coli E24377A 5586599 EcE24377A_5100 tRNA EcE24377A_5100 NC_009801.1 4512414 4512489 D tRNA-Thr 4512414..4512489 Escherichia coli E24377A 5585982 EcE24377A_5101 tRNA EcE24377A_5101 NC_009801.1 4512498 4512582 D tRNA-Tyr 4512498..4512582 Escherichia coli E24377A 5586448 EcE24377A_5102 tRNA EcE24377A_5102 NC_009801.1 4512699 4512773 D tRNA-Gly 4512699..4512773 Escherichia coli E24377A 5587599 EcE24377A_5103 tRNA EcE24377A_5103 NC_009801.1 4512780 4512855 D tRNA-Thr 4512780..4512855 Escherichia coli E24377A 5590211 EcE24377A_5105 tRNA EcE24377A_5105 NC_009801.1 4546779 4546854 D tRNA-Glu 4546779..4546854 Escherichia coli E24377A 5590142 EcE24377A_5108 tRNA EcE24377A_5108 NC_009801.1 4693953 4694028 R tRNA-Phe complement(4693953..4694028) Escherichia coli E24377A 5588093 EcE24377A_5109 tRNA EcE24377A_5109 NC_009801.1 4724485 4724560 D tRNA-Gly 4724485..4724560 Escherichia coli E24377A 5588324 EcE24377A_5110 tRNA EcE24377A_5110 NC_009801.1 4724597 4724672 D tRNA-Gly 4724597..4724672 Escherichia coli E24377A 5589585 EcE24377A_5111 tRNA EcE24377A_5111 NC_009801.1 4724708 4724783 D tRNA-Gly 4724708..4724783 Escherichia coli E24377A 5590839 EcE24377A_5112 tRNA EcE24377A_5112 NC_009801.1 4831854 4831938 D tRNA-Leu 4831854..4831938 Escherichia coli E24377A 5586153 EcE24377A_5113 tRNA EcE24377A_5113 NC_009801.1 4945424 4945510 R tRNA-Leu complement(4945424..4945510) Escherichia coli E24377A 5586924 EcE24377A_5114 tRNA EcE24377A_5114 NC_009801.1 4945545 4945631 R tRNA-Leu complement(4945545..4945631) Escherichia coli E24377A 5590803 EcE24377A_5115 tRNA EcE24377A_5115 NC_009801.1 4945660 4945746 R tRNA-Leu complement(4945660..4945746) Escherichia coli E24377A 5590555 EcE24377A_5003 rRNA rrsA NC_009801.1 225632 227173 D 16S ribosomal RNA 225632..227173 Escherichia coli E24377A 5590458 EcE24377A_5006 rRNA rrlA NC_009801.1 227600 230523 D 23S ribosomal RNA 227600..230523 Escherichia coli E24377A 5588642 EcE24377A_5007 rRNA rrfA NC_009801.1 230616 230735 D 5S ribosomal RNA 230616..230735 Escherichia coli E24377A 5589350 EcE24377A_5053 rRNA rrfB NC_009801.1 2875695 2875814 R 5S ribosomal RNA complement(2875695..2875814) Escherichia coli E24377A 5588060 EcE24377A_5054 rRNA rrlB NC_009801.1 2875908 2878833 R 23S ribosomal RNA complement(2875908..2878833) Escherichia coli E24377A 5586911 EcE24377A_5056 rRNA rrsB NC_009801.1 2879244 2880785 R 16S ribosomal RNA complement(2879244..2880785) Escherichia coli E24377A 5587351 EcE24377A_r01 rRNA EcE24377A_r01 NC_009801.1 3753228 3753346 R 5S ribosomal RNA complement(3753228..3753346) Escherichia coli E24377A 5696493 EcE24377A_5074 rRNA rrfC NC_009801.1 3753473 3753592 R 5S ribosomal RNA complement(3753473..3753592) Escherichia coli E24377A 5586426 EcE24377A_5075 rRNA rrlC NC_009801.1 3753685 3756608 R 23S ribosomal RNA complement(3753685..3756608) Escherichia coli E24377A 5586775 EcE24377A_5078 rRNA rrsC NC_009801.1 3757035 3758576 R 16S ribosomal RNA complement(3757035..3758576) Escherichia coli E24377A 5586563 EcE24377A_5081 rRNA rrsD NC_009801.1 4263705 4265246 D 16S ribosomal RNA 4263705..4265246 Escherichia coli E24377A 5589978 EcE24377A_5083 rRNA rrlD NC_009801.1 4265581 4268504 D 23S ribosomal RNA 4265581..4268504 Escherichia coli E24377A 5589527 EcE24377A_5084 rRNA rrfD NC_009801.1 4268597 4268716 D 5S ribosomal RNA 4268597..4268716 Escherichia coli E24377A 5587994 EcE24377A_5091 rRNA rrsE NC_009801.1 4360914 4362454 D 16S ribosomal RNA 4360914..4362454 Escherichia coli E24377A 5590374 EcE24377A_5094 rRNA rrlE NC_009801.1 4362881 4365804 D 23S ribosomal RNA 4362881..4365804 Escherichia coli E24377A 5586969 EcE24377A_5095 rRNA rrfE NC_009801.1 4365898 4366017 D 5S ribosomal RNA 4365898..4366017 Escherichia coli E24377A 5586600 EcE24377A_5096 rRNA rrsF NC_009801.1 4503771 4505312 D 16S ribosomal RNA 4503771..4505312 Escherichia coli E24377A 5586842 EcE24377A_5098 rRNA rrlF NC_009801.1 4505647 4508570 D 23S ribosomal RNA 4505647..4508570 Escherichia coli E24377A 5590146 EcE24377A_5099 rRNA rrfF NC_009801.1 4508663 4508782 D 5S ribosomal RNA 4508663..4508782 Escherichia coli E24377A 5586680 EcE24377A_5104 rRNA rrsG NC_009801.1 4545152 4546693 D 16S ribosomal RNA 4545152..4546693 Escherichia coli E24377A 5586602 EcE24377A_5106 rRNA rrlG NC_009801.1 4547028 4549951 D 23S ribosomal RNA 4547028..4549951 Escherichia coli E24377A 5586899 EcE24377A_5107 rRNA rrfG NC_009801.1 4550044 4550163 D 5S ribosomal RNA 4550044..4550163 Escherichia coli E24377A 5587310