-- dump date 20140619_081956 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_001451374.1 157149378 5585685 complement(255..698) 1 NC_009786.1 identified by glimmer; putative; hypothetical protein 698 5585685 EcE24377A_F0001 Escherichia coli E24377A hypothetical protein YP_001451374.1 255 R 331111 CDS YP_001451375.1 157149386 5585660 1352..3262 1 NC_009786.1 identified by similarity to GB:CAC92481.1; hypothetical protein 3262 5585660 EcE24377A_F0002 Escherichia coli E24377A hypothetical protein YP_001451375.1 1352 D 331111 CDS YP_001451376.1 157149388 5585705 3259..3753 1 NC_009786.1 identified by glimmer; putative; hypothetical protein 3753 5585705 EcE24377A_F0003 Escherichia coli E24377A hypothetical protein YP_001451376.1 3259 D 331111 CDS YP_001451377.1 157149373 5585692 complement(4316..5524) 1 NC_009786.1 identified by match to protein family HMM PF00872; IS1414, transposase 5524 5585692 EcE24377A_F0005 Escherichia coli E24377A IS1414, transposase YP_001451377.1 4316 R 331111 CDS YP_001451378.1 157149387 5585625 complement(5640..6656) 1 NC_009786.1 identified by match to protein family HMM PF02371; ISShdy1, transposase 6656 5585625 EcE24377A_F0006 Escherichia coli E24377A ISShdy1, transposase YP_001451378.1 5640 R 331111 CDS YP_001451379.1 157149358 5585668 6771..6923 1 NC_009786.1 identified by glimmer; putative; hypothetical protein 6923 5585668 EcE24377A_F0007 Escherichia coli E24377A hypothetical protein YP_001451379.1 6771 D 331111 CDS YP_001451380.1 157149363 5585683 7123..8085 1 NC_009786.1 identified by similarity to SP:P11904; match to protein family HMM PF06406; plasmid segregation protein ParM 8085 parM 5585683 parM Escherichia coli E24377A plasmid segregation protein ParM YP_001451380.1 7123 D 331111 CDS YP_001451381.1 157149383 5585687 complement(8505..9449) 1 NC_009786.1 identified by glimmer; putative; hypothetical protein 9449 5585687 EcE24377A_F0009 Escherichia coli E24377A hypothetical protein YP_001451381.1 8505 R 331111 CDS YP_001451382.1 157149359 5585680 complement(9772..10053) 1 NC_009786.1 identified by match to protein family HMM PF01381; DNA-binding protein 10053 5585680 EcE24377A_F0010 Escherichia coli E24377A DNA-binding protein YP_001451382.1 9772 R 331111 CDS YP_001451383.1 157149357 5585672 complement(10034..10363) 1 NC_009786.1 identified by match to protein family HMM PF05973; prophage protein gp49 10363 5585672 EcE24377A_F0011 Escherichia coli E24377A prophage protein gp49 YP_001451383.1 10034 R 331111 CDS YP_001451384.1 157149331 5585679 complement(10457..10975) 1 NC_009786.1 IS3 family transposase 10975 5585679 EcE24377A_F0012 Escherichia coli E24377A IS3 family transposase YP_001451384.1 10457 R 331111 CDS YP_001451385.1 157149340 5585691 complement(12193..12384) 1 NC_009786.1 hypothetical protein 12384 5585691 EcE24377A_F0014 Escherichia coli E24377A hypothetical protein YP_001451385.1 12193 R 331111 CDS YP_001451386.1 157149335 5585701 complement(13358..13804) 1 NC_009786.1 This gene is disrupted by the insertion of a group II intron.; identified by match to protein family HMM PF00665; IS629, transposase orfB, truncation 13804 5585701 EcE24377A_F0016 Escherichia coli E24377A IS629, transposase orfB, truncation YP_001451386.1 13358 R 331111 CDS YP_001451387.1 157149350 5585643 complement(13921..15429) 1 NC_009786.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388; group II intron-encoded reverse transcriptase/maturase 15429 5585643 EcE24377A_F0017 Escherichia coli E24377A group II intron-encoded reverse transcriptase/maturase YP_001451387.1 13921 R 331111 CDS YP_001451388.1 157149347 5585665 complement(16036..16146) 1 NC_009786.1 IS629, transposase orfB, truncation 16146 5585665 EcE24377A_F0018 Escherichia coli E24377A IS629, transposase orfB, truncation YP_001451388.1 16036 R 331111 CDS YP_001451389.1 157149360 5585658 complement(16130..16333) 1 NC_009786.1 identified by similarity to GB:ABB64661.1; hypothetical protein 16333 5585658 EcE24377A_F0019 Escherichia coli E24377A hypothetical protein YP_001451389.1 16130 R 331111 CDS YP_001451390.1 157149353 5585630 16616..17425 1 NC_009786.1 identified by similarity to SP:P43530; match to protein family HMM PF01375; heat-labile enterotoxin A 17425 eltA 5585630 eltA Escherichia coli E24377A heat-labile enterotoxin A YP_001451390.1 16616 D 331111 CDS YP_001451391.1 157149384 5585684 complement(18117..18935) 1 NC_009786.1 identified by match to protein family HMM PF00665; ISSd1, transposase orfB 18935 5585684 EcE24377A_F0021 Escherichia coli E24377A ISSd1, transposase orfB YP_001451391.1 18117 R 331111 CDS YP_001451392.1 157149334 5585666 complement(19020..20171) 1 NC_009786.1 identified by match to protein family HMM PF00665; IS30, transposase 20171 5585666 EcE24377A_F0022 Escherichia coli E24377A IS30, transposase YP_001451392.1 19020 R 331111 CDS YP_001451393.1 157149342 5585626 20662..22626 1 NC_009786.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; plasmid partition protein B 22626 5585626 EcE24377A_F0024 Escherichia coli E24377A plasmid partition protein B YP_001451393.1 20662 D 331111 CDS YP_001451394.1 157149354 5585646 22681..23058 1 NC_009786.1 identified by match to protein family HMM PF06290; plasmid SOS inhibition protein B 23058 psiB 5585646 psiB Escherichia coli E24377A plasmid SOS inhibition protein B YP_001451394.1 22681 D 331111 CDS YP_001451395.1 157149352 5585700 23112..23873 1 NC_009786.1 PsiA; plasmid SOS inhibition protein A 23873 5585700 EcE24377A_F0026 Escherichia coli E24377A plasmid SOS inhibition protein A YP_001451395.1 23112 D 331111 CDS YP_001451396.1 157149356 5585649 23815..24129 1 NC_009786.1 identified by similarity to GB:CAC86755.1; hypothetical protein 24129 5585649 EcE24377A_F0027 Escherichia coli E24377A hypothetical protein YP_001451396.1 23815 D 331111 CDS YP_001451397.1 157149333 5585694 25398..25568 1 NC_009786.1 identified by glimmer; putative; hypothetical protein 25568 5585694 EcE24377A_F0028 Escherichia coli E24377A hypothetical protein YP_001451397.1 25398 D 331111 CDS YP_001451398.1 157149390 5585677 25486..25602 1 NC_009786.1 identified by similarity to SP:P14565; protein TraI 25602 traI 5585677 traI Escherichia coli E24377A protein TraI YP_001451398.1 25486 D 331111 CDS YP_001451399.1 157149337 5585695 25622..26368 1 NC_009786.1 identified by similarity to SP:P22710; match to protein family HMM PF05857; match to protein family HMM TIGR02755; conjugal transfer pilus acetylation protein TraX 26368 traX 5585695 traX Escherichia coli E24377A conjugal transfer pilus acetylation protein TraX YP_001451399.1 25622 D 331111 CDS YP_001451400.1 157149366 5585688 26427..27287 1 NC_009786.1 identified by match to protein family HMM PF00561; alpha/beta fold family hydrolase 27287 5585688 EcE24377A_F0031 Escherichia coli E24377A alpha/beta fold family hydrolase YP_001451400.1 26427 D 331111 CDS YP_001451401.2 229220657 5585642 27390..27950 1 NC_009786.1 identified by similarity to SP:P29367; match to protein family HMM PF05286; conjugal transfer fertility inhibition protein FinO 27950 finO 5585642 finO Escherichia coli E24377A conjugal transfer fertility inhibition protein FinO YP_001451401.2 27390 D 331111 CDS YP_001451402.1 157149362 5585639 complement(28151..28333) 1 NC_009786.1 identified by glimmer; putative; hypothetical protein 28333 5585639 EcE24377A_F0033 Escherichia coli E24377A hypothetical protein YP_001451402.1 28151 R 331111 CDS YP_001451403.1 157149374 5585686 28194..28400 1 NC_009786.1 identified by glimmer; putative; hypothetical protein 28400 5585686 EcE24377A_F0034 Escherichia coli E24377A hypothetical protein YP_001451403.1 28194 D 331111 CDS YP_001451404.1 157149379 5585669 28702..29328 1 NC_009786.1 identified by glimmer; putative; hypothetical protein 29328 5585669 EcE24377A_F0035 Escherichia coli E24377A hypothetical protein YP_001451404.1 28702 D 331111 CDS YP_001451405.1 157149391 5585635 29480..30070 1 NC_009786.1 identified by similarity to GB:AAM90728.1; hypothetical protein 30070 5585635 EcE24377A_F0036 Escherichia coli E24377A hypothetical protein YP_001451405.1 29480 D 331111 CDS YP_001451406.1 157149394 5585671 30868..31725 1 NC_009786.1 RepA; replication protein 31725 repA 5585671 repA Escherichia coli E24377A replication protein YP_001451406.1 30868 D 331111 CDS YP_001451407.1 157149385 5585637 32696..33007 1 NC_009786.1 identified by match to protein family HMM PF05973; prophage protein gp49 33007 5585637 EcE24377A_F0038 Escherichia coli E24377A prophage protein gp49 YP_001451407.1 32696 D 331111 CDS YP_001451408.1 157149336 5585652 33007..33294 1 NC_009786.1 identified by match to protein family HMM PF01381; DNA-binding protein 33294 5585652 EcE24377A_F0039 Escherichia coli E24377A DNA-binding protein YP_001451408.1 33007 D 331111 CDS YP_001451409.1 157149370 5585676 33671..34180 1 NC_009786.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 34180 def 5585676 def Escherichia coli E24377A peptide deformylase YP_001451409.1 33671 D 331111 CDS YP_001451410.1 157149393 5585623 34195..34311 1 NC_009786.1 identified by glimmer; putative; hypothetical protein 34311 5585623 EcE24377A_F0041 Escherichia coli E24377A hypothetical protein YP_001451410.1 34195 D 331111 CDS YP_001451411.1 157149355 5585661 34817..35035 1 NC_009786.1 IS630, transposase, truncation 35035 5585661 EcE24377A_F0042 Escherichia coli E24377A IS630, transposase, truncation YP_001451411.1 34817 D 331111 CDS YP_001451412.1 157149376 5585628 complement(36107..37057) 1 NC_009786.1 identified by match to protein family HMM PF04393; hypothetical protein 37057 5585628 EcE24377A_F0044 Escherichia coli E24377A hypothetical protein YP_001451412.1 36107 R 331111 CDS YP_001451413.1 157149369 5585673 complement(37062..38150) 1 NC_009786.1 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 38150 5585673 EcE24377A_F0045 Escherichia coli E24377A glycosyl transferase, group 1 family protein YP_001451413.1 37062 R 331111 CDS YP_001451414.1 157149338 5585624 complement(38153..38974) 1 NC_009786.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein 38974 5585624 EcE24377A_F0046 Escherichia coli E24377A polysaccharide deacetylase family protein YP_001451414.1 38153 R 331111 CDS YP_001451415.1 157149364 5585622 complement(39239..39781) 1 NC_009786.1 identified by similarity to GB:AAZ89280.1; hypothetical protein 39781 5585622 EcE24377A_F0047 Escherichia coli E24377A hypothetical protein YP_001451415.1 39239 R 331111 CDS YP_001451416.1 157149349 5585662 complement(39781..40038) 1 NC_009786.1 identified by similarity to GB:AAZ89279.1; hypothetical protein 40038 5585662 EcE24377A_F0048 Escherichia coli E24377A hypothetical protein YP_001451416.1 39781 R 331111 CDS YP_001451417.1 157149398 5585697 40560..40778 1 NC_009786.1 identified by similarity to SP:P62552; match to protein family HMM PF07362; plasmid maintenance protein CcdA 40778 ccdA2 5585697 ccdA2 Escherichia coli E24377A plasmid maintenance protein CcdA YP_001451417.1 40560 D 331111 CDS YP_001451418.1 157149344 5585702 40780..41085 1 NC_009786.1 controlled cell death protein; post-segregation toxin; toxin addiction system; plasmid maintenance protein CcdB 41085 ccdB1 5585702 ccdB1 Escherichia coli E24377A plasmid maintenance protein CcdB YP_001451418.1 40780 D 331111 CDS YP_001451419.1 157149395 5585654 41086..41892 1 NC_009786.1 identified by similarity to SP:P06615; match to protein family HMM PF00589; resolvase 41892 resD 5585654 resD Escherichia coli E24377A resolvase YP_001451419.1 41086 D 331111 CDS YP_001451420.1 157149346 5585629 42070..42714 1 NC_009786.1 identified by similarity to SP:P07175; ParA protein 42714 5585629 EcE24377A_F0052 Escherichia coli E24377A ParA protein YP_001451420.1 42070 D 331111 CDS YP_001451421.1 157149361 5585651 42801..43109 1 NC_009786.1 identified by similarity to GB:AAK48856.1; putative 60 kDa chaperonin 43109 5585651 EcE24377A_F0053 Escherichia coli E24377A putative 60 kDa chaperonin YP_001451421.1 42801 D 331111 CDS YP_001451422.1 157149343 5585636 45986..46159 1 NC_009786.1 hypothetical protein 46159 5585636 EcE24377A_F0056 Escherichia coli E24377A hypothetical protein YP_001451422.1 45986 D 331111 CDS YP_001451423.1 157149348 5585632 47406..48203 1 NC_009786.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein 48203 5585632 EcE24377A_F0058 Escherichia coli E24377A IS21 family transposition helper protein YP_001451423.1 47406 D 331111 CDS YP_001451424.1 157149381 5585664 49061..49786 1 NC_009786.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; periplasmic pilus chaperone CS3-1 49786 5585664 EcE24377A_F0060 Escherichia coli E24377A periplasmic pilus chaperone CS3-1 YP_001451424.1 49061 D 331111 CDS YP_001451425.1 157149380 5585656 54098..54520 1 NC_009786.1 identified by similarity to GB:AAP16553.1; IS91, orf2 54520 5585656 EcE24377A_F0062 Escherichia coli E24377A IS91, orf2 YP_001451425.1 54098 D 331111 CDS YP_001451426.1 157149365 5585703 55626..55901 1 NC_009786.1 identified by match to protein family HMM PF03811; IS1, transposase orfA 55901 5585703 EcE24377A_F0064 Escherichia coli E24377A IS1, transposase orfA YP_001451426.1 55626 D 331111 CDS YP_001451427.1 157149375 5585620 55820..56323 1 NC_009786.1 identified by match to protein family HMM PF03400; IS1, transposase orfB 56323 5585620 EcE24377A_F0065 Escherichia coli E24377A IS1, transposase orfB YP_001451427.1 55820 D 331111 CDS YP_001451428.1 157149368 5585640 56818..57615 1 NC_009786.1 identified by similarity to SP:P16114; match to protein family HMM PF00165; AraC family transcription regulator 57615 rns 5585640 rns Escherichia coli E24377A AraC family transcription regulator YP_001451428.1 56818 D 331111 CDS YP_001451429.1 157149397 5585644 complement(58816..59238) 1 NC_009786.1 identified by similarity to GB:AAP16553.1; IS91, orf2 59238 5585644 EcE24377A_F0068 Escherichia coli E24377A IS91, orf2 YP_001451429.1 58816 R 331111 CDS YP_001451430.1 157149332 5585670 60596..61735 1 NC_009786.1 identified by match to protein family HMM PF02687; putative efflux ABC transporter, permease protein 61735 5585670 EcE24377A_F0070 Escherichia coli E24377A putative efflux ABC transporter, permease protein YP_001451430.1 60596 D 331111 CDS YP_001451431.1 157149392 5585696 61768..62934 1 NC_009786.1 identified by glimmer; putative; hypothetical protein 62934 5585696 EcE24377A_F0071 Escherichia coli E24377A hypothetical protein YP_001451431.1 61768 D 331111 CDS YP_001451432.1 157149396 5585675 62891..63664 1 NC_009786.1 identified by glimmer; putative; hypothetical protein 63664 5585675 EcE24377A_F0072 Escherichia coli E24377A hypothetical protein YP_001451432.1 62891 D 331111 CDS YP_001451433.1 157149339 5585645 66131..66496 1 NC_009786.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 66496 5585645 EcE24377A_F0075 Escherichia coli E24377A insertion sequence 2 OrfA protein YP_001451433.1 66131 D 331111 CDS YP_001451434.1 157149341 5585690 66454..67365 1 NC_009786.1 identified by similarity to SP:P51026; match to protein family HMM PF00665; IS2, transposase orfB 67365 5585690 EcE24377A_F0076 Escherichia coli E24377A IS2, transposase orfB YP_001451434.1 66454 D 331111 CDS YP_001451435.1 157149345 5585647 68024..68308 1 NC_009786.1 IS1414, transposase, truncation 68308 5585647 EcE24377A_F0077 Escherichia coli E24377A IS1414, transposase, truncation YP_001451435.1 68024 D 331111 CDS YP_001451436.1 157149389 5585678 68336..68635 1 NC_009786.1 identified by match to protein family HMM PF01527; IS3, transposase orfA 68635 5585678 EcE24377A_F0078 Escherichia coli E24377A IS3, transposase orfA YP_001451436.1 68336 D 331111 CDS YP_001451437.1 157149372 5585634 complement(69998..71284) 1 NC_009786.1 hypothetical protein 71284 5585634 EcE24377A_F0081 Escherichia coli E24377A hypothetical protein YP_001451437.1 69998 R 331111 CDS YP_001451438.1 157149367 5585633 complement(72375..72674) 1 NC_009786.1 identified by match to protein family HMM PF01527; IS3, transposase orfA 72674 5585633 EcE24377A_F0083 Escherichia coli E24377A IS3, transposase orfA YP_001451438.1 72375 R 331111 CDS YP_001451439.1 157149377 5585674 complement(73885..74250) 1 NC_009786.1 identified by similarity to GB:AAP16553.1; IS91, orf2 74250 5585674 EcE24377A_F0085 Escherichia coli E24377A IS91, orf2 YP_001451439.1 73885 R 331111 CDS YP_001451440.1 157149382 5585621 74269..74940 1 NC_009786.1 identified by match to protein family HMM PF00665; IS2, transposase orfB, truncation 74940 5585621 EcE24377A_F0086 Escherichia coli E24377A IS2, transposase orfB, truncation YP_001451440.1 74269 D 331111 CDS YP_001451441.1 157149351 5585653 75209..76954 1 NC_009786.1 identified by match to protein family HMM PF08479; hypothetical protein 76954 5585653 EcE24377A_F0087 Escherichia coli E24377A hypothetical protein YP_001451441.1 75209 D 331111 CDS YP_001451442.1 157149405 5585707 complement(4718..6949) 1 NC_009787.1 identified by similarity to SP:P22708; match to protein family HMM TIGR02759; type IV conjugative transfer system coupling protein TraD 6949 traD 5585707 traD Escherichia coli E24377A type IV conjugative transfer system coupling protein TraD YP_001451442.1 4718 R 331111 CDS YP_001451443.1 157149414 5585733 complement(7093..7830) 1 NC_009787.1 identified by similarity to SP:P13980; match to protein family HMM PF05818; TraT complement resistance protein 7830 traT 5585733 traT Escherichia coli E24377A TraT complement resistance protein YP_001451443.1 7093 R 331111 CDS YP_001451444.1 157149422 5585727 complement(8583..11465) 1 NC_009787.1 identified by similarity to SP:P33790; match to protein family HMM PF07916; conjugal transfer mating pair stabilization protein TraG 11465 traG 5585727 traG Escherichia coli E24377A conjugal transfer mating pair stabilization protein TraG YP_001451444.1 8583 R 331111 CDS YP_001451445.1 157149420 5585717 complement(11467..12972) 1 NC_009787.1 identified by similarity to SP:P15069; match to protein family HMM PF06122; conjugal transfer pilus assembly protein TraH 12972 traH 5585717 traH Escherichia coli E24377A conjugal transfer pilus assembly protein TraH YP_001451445.1 11467 R 331111 CDS YP_001451446.1 157149423 5585719 complement(12884..13753) 1 NC_009787.1 identified by similarity to GB:AAN52975.1; hypothetical protein 13753 5585719 EcE24377A_C0005 Escherichia coli E24377A hypothetical protein YP_001451446.1 12884 R 331111 CDS YP_001451447.1 157149403 5585716 complement(14130..14270) 1 NC_009787.1 identified by glimmer; putative; hypothetical protein 14270 5585716 EcE24377A_C0006 Escherichia coli E24377A hypothetical protein YP_001451447.1 14130 R 331111 CDS YP_001451448.1 157149402 5585735 complement(15035..15226) 1 NC_009787.1 hypothetical protein 15226 5585735 EcE24377A_C0007 Escherichia coli E24377A hypothetical protein YP_001451448.1 15035 R 331111 CDS YP_001451449.1 157149421 5585720 complement(15223..15645) 1 NC_009787.1 identified by similarity to GB:AAS76405.1; hypothetical protein 15645 5585720 EcE24377A_C0008 Escherichia coli E24377A hypothetical protein YP_001451449.1 15223 R 331111 CDS YP_001451450.1 157149412 5585718 complement(15692..16117) 1 NC_009787.1 identified by match to protein family HMM PF03230; antirestriction protein 16117 5585718 EcE24377A_C0009 Escherichia coli E24377A antirestriction protein YP_001451450.1 15692 R 331111 CDS YP_001451451.1 157149409 5585729 complement(16529..17299) 1 NC_009787.1 identified by similarity to GB:BAB91623.1; hypothetical protein 17299 5585729 EcE24377A_C0010 Escherichia coli E24377A hypothetical protein YP_001451451.1 16529 R 331111 CDS YP_001451452.1 157149424 5585710 complement(17344..17778) 1 NC_009787.1 identified by similarity to GB:AAR05672.1; match to protein family HMM PF07128; hypothetical protein 17778 5585710 EcE24377A_C0011 Escherichia coli E24377A hypothetical protein YP_001451452.1 17344 R 331111 CDS YP_001451453.1 157149400 5585715 complement(17792..18013) 1 NC_009787.1 identified by similarity to GB:CAG27544.1; hypothetical protein 18013 5585715 EcE24377A_C0012 Escherichia coli E24377A hypothetical protein YP_001451453.1 17792 R 331111 CDS YP_001451454.1 157149426 5585726 complement(18014..18697) 1 NC_009787.1 identified by match to protein family HMM PF01555; putative methylase 18697 5585726 EcE24377A_C0013 Escherichia coli E24377A putative methylase YP_001451454.1 18014 R 331111 CDS YP_001451455.1 157149428 5585712 18804..18929 1 NC_009787.1 identified by similarity to GB:AAS76411.1; hypothetical protein 18929 5585712 EcE24377A_C0014 Escherichia coli E24377A hypothetical protein YP_001451455.1 18804 D 331111 CDS YP_001451456.1 157149410 5585709 complement(19081..20007) 1 NC_009787.1 identified by similarity to GB:AAS76414.1; match to protein family HMM PF06924; hypothetical protein 20007 5585709 EcE24377A_C0015 Escherichia coli E24377A hypothetical protein YP_001451456.1 19081 R 331111 CDS YP_001451457.1 157149411 5585731 20124..20249 1 NC_009787.1 identified by similarity to GB:AAS76411.1; hypothetical protein 20249 5585731 EcE24377A_C0016 Escherichia coli E24377A hypothetical protein YP_001451457.1 20124 D 331111 CDS YP_001451458.1 157149427 5585730 complement(20408..20836) 1 NC_009787.1 identified by similarity to SP:P11906; protein stbB 20836 5585730 EcE24377A_C0017 Escherichia coli E24377A protein stbB YP_001451458.1 20408 R 331111 CDS YP_001451459.1 157149418 5585711 complement(20833..21813) 1 NC_009787.1 identified by similarity to SP:P11904; match to protein family HMM PF06406; plasmid segregation protein ParM 21813 parM 5585711 parM Escherichia coli E24377A plasmid segregation protein ParM YP_001451459.1 20833 R 331111 CDS YP_001451460.1 157149417 5585722 complement(22556..23590) 1 NC_009787.1 identified by similarity to GB:CAD76448.1; hypothetical protein 23590 5585722 EcE24377A_C0019 Escherichia coli E24377A hypothetical protein YP_001451460.1 22556 R 331111 CDS YP_001451461.1 157149413 5585723 complement(24197..25201) 1 NC_009787.1 identified by glimmer; putative; hypothetical protein 25201 5585723 EcE24377A_C0020 Escherichia coli E24377A hypothetical protein YP_001451461.1 24197 R 331111 CDS YP_001451462.1 157149416 5585728 complement(25355..25630) 1 NC_009787.1 identified by match to protein family HMM PF05016; RelE/ParE family plasmid stabilization system protein 25630 5585728 EcE24377A_C0021 Escherichia coli E24377A RelE/ParE family plasmid stabilization system protein YP_001451462.1 25355 R 331111 CDS YP_001451463.1 157149404 5585724 complement(25630..25908) 1 NC_009787.1 identified by match to protein family HMM PF01402; CopG family protein 25908 5585724 EcE24377A_C0022 Escherichia coli E24377A CopG family protein YP_001451463.1 25630 R 331111 CDS YP_001451464.1 157149425 5585734 complement(26436..26885) 1 NC_009787.1 identified by glimmer; putative; hypothetical protein 26885 5585734 EcE24377A_C0023 Escherichia coli E24377A hypothetical protein YP_001451464.1 26436 R 331111 CDS YP_001451465.1 157149408 5585714 27303..28130 1 NC_009787.1 identified by glimmer; putative; hypothetical protein 28130 5585714 EcE24377A_C0024 Escherichia coli E24377A hypothetical protein YP_001451465.1 27303 D 331111 CDS YP_001451466.1 157149419 5585732 complement(29051..29908) 1 NC_009787.1 RepA; replication protein 29908 repA 5585732 repA Escherichia coli E24377A replication protein YP_001451466.1 29051 R 331111 CDS YP_001451467.1 157149415 5585721 complement(30630..30827) 1 NC_009787.1 identified by similarity to SP:P13970; match to protein family HMM PF01848; protein SrnB 30827 srnB 5585721 srnB Escherichia coli E24377A protein SrnB YP_001451467.1 30630 R 331111 CDS YP_001451468.1 157149401 5585725 complement(30904..31899) 1 NC_009787.1 identified by similarity to GB:BAB78149.1; hypothetical protein 31899 5585725 EcE24377A_C0027 Escherichia coli E24377A hypothetical protein YP_001451468.1 30904 R 331111 CDS YP_001451469.1 157149406 5585713 complement(32479..33237) 1 NC_009787.1 identified by similarity to SP:P22710; match to protein family HMM PF05857; match to protein family HMM TIGR02755; type-F conjugative transfer system pilin acetylase TraX 33237 traX 5585713 traX Escherichia coli E24377A type-F conjugative transfer system pilin acetylase TraX YP_001451469.1 32479 R 331111 CDS YP_001451470.1 157149407 5585708 complement(33207..33773) 1 NC_009787.1 identified by similarity to GB:AAM90728.1; hypothetical protein 33773 5585708 EcE24377A_C0029 Escherichia coli E24377A hypothetical protein YP_001451470.1 33207 R 331111 CDS YP_001451471.1 157149467 5585790 complement(903..1136) 1 NC_009788.1 identified by similarity to GB:AAR05684.1; match to protein family HMM PF06006; hypothetical protein 1136 5585790 EcE24377A_D0001 Escherichia coli E24377A hypothetical protein YP_001451471.1 903 R 331111 CDS YP_001451472.1 157149468 5585773 complement(1194..1721) 1 NC_009788.1 identified by similarity to SP:P28043; match to protein family HMM PF00436; match to protein family HMM TIGR00621; single-stranded DNA-binding protein 1721 5585773 EcE24377A_D0002 Escherichia coli E24377A single-stranded DNA-binding protein YP_001451472.1 1194 R 331111 CDS YP_001451473.1 157149478 5585807 complement(2491..2682) 1 NC_009788.1 identified by similarity to GB:AAS76404.1; hypothetical protein 2682 5585807 EcE24377A_D0003 Escherichia coli E24377A hypothetical protein YP_001451473.1 2491 R 331111 CDS YP_001451474.1 157149470 5585746 complement(2679..3101) 1 NC_009788.1 identified by similarity to GB:AAR05676.1; hypothetical protein 3101 5585746 EcE24377A_D0004 Escherichia coli E24377A hypothetical protein YP_001451474.1 2679 R 331111 CDS YP_001451475.1 157149453 5585794 complement(3148..3573) 1 NC_009788.1 identified by match to protein family HMM PF03230; antirestriction family protein 3573 5585794 EcE24377A_D0005 Escherichia coli E24377A antirestriction family protein YP_001451475.1 3148 R 331111 CDS YP_001451476.1 157149449 5585796 complement(3990..4760) 1 NC_009788.1 identified by similarity to GB:AAS76407.1; hypothetical protein 4760 5585796 EcE24377A_D0006 Escherichia coli E24377A hypothetical protein YP_001451476.1 3990 R 331111 CDS YP_001451477.1 157149445 5585762 complement(4805..5239) 1 NC_009788.1 identified by similarity to GB:CAG27545.1; match to protein family HMM PF07128; hypothetical protein 5239 5585762 EcE24377A_D0007 Escherichia coli E24377A hypothetical protein YP_001451477.1 4805 R 331111 CDS YP_001451478.1 157149446 5585739 complement(5253..5474) 1 NC_009788.1 identified by similarity to GB:AAS76409.1; hypothetical protein 5474 5585739 EcE24377A_D0008 Escherichia coli E24377A hypothetical protein YP_001451478.1 5253 R 331111 CDS YP_001451479.1 157149435 5585786 complement(5475..6158) 1 NC_009788.1 identified by match to protein family HMM PF01555; putative methylase 6158 5585786 EcE24377A_D0009 Escherichia coli E24377A putative methylase YP_001451479.1 5475 R 331111 CDS YP_001451480.1 157149487 5585759 6266..6391 1 NC_009788.1 identified by similarity to GB:AAS76411.1; hypothetical protein 6391 5585759 EcE24377A_D0010 Escherichia coli E24377A hypothetical protein YP_001451480.1 6266 D 331111 CDS YP_001451481.1 157149483 5585772 complement(6542..7468) 1 NC_009788.1 identified by similarity to GB:AAL72290.1; match to protein family HMM PF06924; hypothetical protein 7468 5585772 EcE24377A_D0011 Escherichia coli E24377A hypothetical protein YP_001451481.1 6542 R 331111 CDS YP_001451482.1 157149475 5585771 complement(8125..8517) 1 NC_009788.1 stable plasmid inheritance protein 8517 5585771 EcE24377A_D0012 Escherichia coli E24377A stable plasmid inheritance protein YP_001451482.1 8125 R 331111 CDS YP_001451483.1 157149477 5585749 complement(8521..9495) 1 NC_009788.1 identified by similarity to SP:P11904; match to protein family HMM PF06406; plasmid segregation protein ParM 9495 parM 5585749 parM Escherichia coli E24377A plasmid segregation protein ParM YP_001451483.1 8521 R 331111 CDS YP_001451484.1 157149457 5585744 complement(11342..12175) 1 NC_009788.1 identified by similarity to SP:P06615; match to protein family HMM PF00589; resolvase 12175 resD 5585744 resD Escherichia coli E24377A resolvase YP_001451484.1 11342 R 331111 CDS YP_001451485.1 157149451 5585764 complement(12129..12542) 1 NC_009788.1 identified by similarity to GB:AAA24254.1; hypothetical protein 12542 5585764 EcE24377A_D0015 Escherichia coli E24377A hypothetical protein YP_001451485.1 12129 R 331111 CDS YP_001451486.1 157149447 5585791 complement(12578..12673) 1 NC_009788.1 identified by glimmer; putative; hypothetical protein 12673 5585791 EcE24377A_D0016 Escherichia coli E24377A hypothetical protein YP_001451486.1 12578 R 331111 CDS YP_001451487.1 157149443 5585801 13328..13744 1 NC_009788.1 identified by match to protein family HMM PF01850; PilT domain-containing protein 13744 5585801 EcE24377A_D0017 Escherichia coli E24377A PilT domain-containing protein YP_001451487.1 13328 D 331111 CDS YP_001451488.1 157149473 5585750 complement(13906..16044) 1 NC_009788.1 identified by similarity to GB:AAM37285.1; hypothetical protein 16044 5585750 EcE24377A_D0018 Escherichia coli E24377A hypothetical protein YP_001451488.1 13906 R 331111 CDS YP_001451489.1 157149433 5585763 complement(16360..17898) 1 NC_009788.1 identified by match to protein family HMM PF03050; IS66 family transposase 17898 5585763 EcE24377A_D0019 Escherichia coli E24377A IS66 family transposase YP_001451489.1 16360 R 331111 CDS YP_001451490.1 157149454 5585784 complement(17948..18295) 1 NC_009788.1 identified by match to protein family HMM PF05717; IS66 family orf2 18295 5585784 EcE24377A_D0020 Escherichia coli E24377A IS66 family orf2 YP_001451490.1 17948 R 331111 CDS YP_001451491.1 157149460 5585792 complement(18292..18681) 1 NC_009788.1 identified by match to protein family HMM PF01527; IS66 family orf1 18681 5585792 EcE24377A_D0021 Escherichia coli E24377A IS66 family orf1 YP_001451491.1 18292 R 331111 CDS YP_001451492.1 157149437 5585776 18981..19097 1 NC_009788.1 identified by similarity to GB:AAZ89279.1; hypothetical protein 19097 5585776 EcE24377A_D0022 Escherichia coli E24377A hypothetical protein YP_001451492.1 18981 D 331111 CDS YP_001451493.1 157149441 5585751 19097..19687 1 NC_009788.1 identified by similarity to GB:AAZ89280.1; hypothetical protein 19687 5585751 EcE24377A_D0023 Escherichia coli E24377A hypothetical protein YP_001451493.1 19097 D 331111 CDS YP_001451494.1 157149497 5585756 complement(19705..20052) 1 NC_009788.1 identified by similarity to GB:AAA23190.1; hypothetical protein 20052 5585756 EcE24377A_D0024 Escherichia coli E24377A hypothetical protein YP_001451494.1 19705 R 331111 CDS YP_001451495.1 157149436 5585748 20712..20996 1 NC_009788.1 identified by glimmer; putative; hypothetical protein 20996 5585748 EcE24377A_D0026 Escherichia coli E24377A hypothetical protein YP_001451495.1 20712 D 331111 CDS YP_001451496.1 157149456 5585777 20996..21856 1 NC_009788.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 21856 5585777 EcE24377A_D0027 Escherichia coli E24377A AraC family transcriptional regulator YP_001451496.1 20996 D 331111 CDS YP_001451497.1 157149486 5585779 22166..23368 1 NC_009788.1 identified by match to protein family HMM PF01609; IS186, transposase 23368 5585779 EcE24377A_D0028 Escherichia coli E24377A IS186, transposase YP_001451497.1 22166 D 331111 CDS YP_001451498.1 157149481 5585740 complement(24963..25055) 1 NC_009788.1 identified by glimmer; putative; hypothetical protein 25055 5585740 EcE24377A_D0030 Escherichia coli E24377A hypothetical protein YP_001451498.1 24963 R 331111 CDS YP_001451499.1 157149462 5585781 complement(25398..26027) 1 NC_009788.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 26027 5585781 EcE24377A_D0031 Escherichia coli E24377A AraC family transcriptional regulator YP_001451499.1 25398 R 331111 CDS YP_001451500.1 157149440 5585742 complement(27290..28060) 1 NC_009788.1 identified by match to protein family HMM PF08388; hypothetical protein 28060 5585742 EcE24377A_D0032 Escherichia coli E24377A hypothetical protein YP_001451500.1 27290 R 331111 CDS YP_001451501.1 157149469 5585743 28840..29205 1 NC_009788.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 29205 5585743 EcE24377A_D0033 Escherichia coli E24377A insertion sequence 2 OrfA protein YP_001451501.1 28840 D 331111 CDS YP_001451502.1 157149455 5585808 29163..30068 1 NC_009788.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 30068 5585808 EcE24377A_D0034 Escherichia coli E24377A insertion element IS2 transposase InsD YP_001451502.1 29163 D 331111 CDS YP_001451503.1 157149450 5585805 complement(30756..31847) 1 NC_009788.1 identified by match to protein family HMM PF07434; fimbrial protein 31847 5585805 EcE24377A_D0035 Escherichia coli E24377A fimbrial protein YP_001451503.1 30756 R 331111 CDS YP_001451504.1 157149430 5585758 complement(31844..34462) 1 NC_009788.1 identified by similarity to GB:AAK97136.1; fimbrial usher family protein 34462 5585758 EcE24377A_D0036 Escherichia coli E24377A fimbrial usher family protein YP_001451504.1 31844 R 331111 CDS YP_001451505.1 157149448 5585804 complement(35110..35826) 1 NC_009788.1 identified by glimmer; putative; hypothetical protein 35826 5585804 EcE24377A_D0037 Escherichia coli E24377A hypothetical protein YP_001451505.1 35110 R 331111 CDS YP_001451506.1 157149484 5585810 35933..36262 1 NC_009788.1 identified by glimmer; putative; hypothetical protein 36262 5585810 EcE24377A_D0038 Escherichia coli E24377A hypothetical protein YP_001451506.1 35933 D 331111 CDS YP_001451507.1 157149479 5585745 complement(38505..38696) 1 NC_009788.1 identified by glimmer; putative; hypothetical protein 38696 5585745 EcE24377A_D0041 Escherichia coli E24377A hypothetical protein YP_001451507.1 38505 R 331111 CDS YP_001451508.1 157149439 5585767 complement(38758..39552) 1 NC_009788.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein 39552 5585767 EcE24377A_D0042 Escherichia coli E24377A IS21 family transposition helper protein YP_001451508.1 38758 R 331111 CDS YP_001451509.1 157149494 5585768 complement(39552..40724) 1 NC_009788.1 identified by similarity to SP:P15025; match to protein family HMM PF00665; IS21 family transposase 40724 5585768 EcE24377A_D0043 Escherichia coli E24377A IS21 family transposase YP_001451509.1 39552 R 331111 CDS YP_001451510.1 157149463 5585798 complement(41361..41555) 1 NC_009788.1 hypothetical protein 41555 5585798 EcE24377A_D0044 Escherichia coli E24377A hypothetical protein YP_001451510.1 41361 R 331111 CDS YP_001451511.1 157149488 5585799 complement(41552..41821) 1 NC_009788.1 hypothetical protein 41821 5585799 EcE24377A_D0045 Escherichia coli E24377A hypothetical protein YP_001451511.1 41552 R 331111 CDS YP_001451512.1 157149432 5585800 41618..41728 1 NC_009788.1 identified by glimmer; putative; hypothetical protein 41728 5585800 EcE24377A_D0046 Escherichia coli E24377A hypothetical protein YP_001451512.1 41618 D 331111 CDS YP_001451513.1 157149471 5585770 complement(42732..43763) 1 NC_009788.1 identified by similarity to SP:P18023; replication initiation protein 43763 repZ 5585770 repZ Escherichia coli E24377A replication initiation protein YP_001451513.1 42732 R 331111 CDS YP_001451514.1 157149464 5585806 45646..46179 1 NC_009788.1 identified by match to protein family HMM PF02357; transcription termination factor NusG domain-containing protein 46179 5585806 EcE24377A_D0048 Escherichia coli E24377A transcription termination factor NusG domain-containing protein YP_001451514.1 45646 D 331111 CDS YP_001451515.1 157149491 5585761 46432..47115 1 NC_009788.1 hypothetical protein 47115 5585761 EcE24377A_D0049 Escherichia coli E24377A hypothetical protein YP_001451515.1 46432 D 331111 CDS YP_001451516.1 157149485 5585736 48744..49811 1 NC_009788.1 identified by similarity to GB:AAL05516.1; PilL protein 49811 5585736 EcE24377A_D0051 Escherichia coli E24377A PilL protein YP_001451516.1 48744 D 331111 CDS YP_001451517.1 157149492 5585787 49811..50248 1 NC_009788.1 identified by match to protein family HMM PF07419; PilM protein 50248 5585787 EcE24377A_D0052 Escherichia coli E24377A PilM protein YP_001451517.1 49811 D 331111 CDS YP_001451518.1 157149482 5585765 50477..50803 1 NC_009788.1 identified by match to protein family HMM PF01527; IS629, transposase orfA 50803 5585765 EcE24377A_D0053 Escherichia coli E24377A IS629, transposase orfA YP_001451518.1 50477 D 331111 CDS YP_001451519.1 157149465 5585775 51889..53397 1 NC_009788.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388; group II intron-encoded reverse transcriptase/maturase 53397 5585775 EcE24377A_D0055 Escherichia coli E24377A group II intron-encoded reverse transcriptase/maturase YP_001451519.1 51889 D 331111 CDS YP_001451520.1 157149444 5585803 53944..55716 1 NC_009788.1 hypothetical protein 55716 5585803 EcE24377A_D0057 Escherichia coli E24377A hypothetical protein YP_001451520.1 53944 D 331111 CDS YP_001451521.1 157149495 5585795 complement(55753..58452) 1 NC_009788.1 identified by match to protein family HMM PF03432; relaxase/mobilization nuclease domain-containing protein 58452 5585795 EcE24377A_D0058 Escherichia coli E24377A relaxase/mobilization nuclease domain-containing protein YP_001451521.1 55753 R 331111 CDS YP_001451522.1 157149438 5585809 59029..59364 1 NC_009788.1 hypothetical protein 59364 5585809 EcE24377A_D0059 Escherichia coli E24377A hypothetical protein YP_001451522.1 59029 D 331111 CDS YP_001451523.1 157149493 5585780 complement(59450..60298) 1 NC_009788.1 hypothetical protein 60298 5585780 EcE24377A_D0060 Escherichia coli E24377A hypothetical protein YP_001451523.1 59450 R 331111 CDS YP_001451524.1 157149472 5585737 60879..60974 1 NC_009788.1 hypothetical protein 60974 5585737 EcE24377A_D0062 Escherichia coli E24377A hypothetical protein YP_001451524.1 60879 D 331111 CDS YP_001451525.1 157149461 5585769 complement(61001..62572) 1 NC_009788.1 identified by match to protein family HMM PF03050; IS66 family transposase 62572 5585769 EcE24377A_D0063 Escherichia coli E24377A IS66 family transposase YP_001451525.1 61001 R 331111 CDS YP_001451526.1 157149431 5585752 complement(62592..62939) 1 NC_009788.1 identified by match to protein family HMM PF05717; IS66 family orf2 62939 5585752 EcE24377A_D0064 Escherichia coli E24377A IS66 family orf2 YP_001451526.1 62592 R 331111 CDS YP_001451527.1 157149452 5585783 complement(62939..63616) 1 NC_009788.1 identified by match to protein family HMM PF01527; IS66 family orf1 63616 5585783 EcE24377A_D0065 Escherichia coli E24377A IS66 family orf1 YP_001451527.1 62939 R 331111 CDS YP_001451528.1 157149466 5585738 63703..63837 1 NC_009788.1 hypothetical protein 63837 5585738 EcE24377A_D0066 Escherichia coli E24377A hypothetical protein YP_001451528.1 63703 D 331111 CDS YP_001451529.1 157149490 5585753 complement(63868..64026) 1 NC_009788.1 hypothetical protein 64026 5585753 EcE24377A_D0067 Escherichia coli E24377A hypothetical protein YP_001451529.1 63868 R 331111 CDS YP_001451530.1 157149442 5585788 complement(64089..64979) 1 NC_009788.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; putative transposase 64979 5585788 EcE24377A_D0068 Escherichia coli E24377A putative transposase YP_001451530.1 64089 R 331111 CDS YP_001451531.1 157149434 5585802 complement(64976..65440) 1 NC_009788.1 hypothetical protein 65440 5585802 EcE24377A_D0069 Escherichia coli E24377A hypothetical protein YP_001451531.1 64976 R 331111 CDS YP_001451532.1 157149459 5585782 complement(65542..65808) 1 NC_009788.1 hypothetical protein 65808 5585782 EcE24377A_D0070 Escherichia coli E24377A hypothetical protein YP_001451532.1 65542 R 331111 CDS YP_001451533.1 157149496 5585797 complement(65902..66336) 1 NC_009788.1 hypothetical protein 66336 5585797 EcE24377A_D0071 Escherichia coli E24377A hypothetical protein YP_001451533.1 65902 R 331111 CDS YP_001451534.1 157149476 5585741 complement(66580..66675) 1 NC_009788.1 identified by glimmer; putative; hypothetical protein 66675 5585741 EcE24377A_D0072 Escherichia coli E24377A hypothetical protein YP_001451534.1 66580 R 331111 CDS YP_001451535.1 157149474 5585789 complement(67065..67625) 1 NC_009788.1 identified by match to protein family HMM PF07275; putative anti-restriction protein 67625 5585789 EcE24377A_D0073 Escherichia coli E24377A putative anti-restriction protein YP_001451535.1 67065 R 331111 CDS YP_001451536.1 157149489 5585755 complement(67697..68293) 1 NC_009788.1 identified by similarity to GB:BAB91633.1; hypothetical protein 68293 5585755 EcE24377A_D0074 Escherichia coli E24377A hypothetical protein YP_001451536.1 67697 R 331111 CDS YP_001451537.1 157149458 5585793 complement(68290..69009) 1 NC_009788.1 PsiA; plasmid SOS inhibition protein A 69009 5585793 EcE24377A_D0075 Escherichia coli E24377A plasmid SOS inhibition protein A YP_001451537.1 68290 R 331111 CDS YP_001451538.1 157149480 5585747 complement(69006..69440) 1 NC_009788.1 identified by match to protein family HMM PF06290; plasmid SOS inhibition protein B 69440 psiB 5585747 psiB Escherichia coli E24377A plasmid SOS inhibition protein B YP_001451538.1 69006 R 331111 CDS YP_001451539.1 157149501 5585816 complement(665..781) 1 NC_009789.1 identified by glimmer; putative; hypothetical protein 781 5585816 EcE24377A_B0001 Escherichia coli E24377A hypothetical protein YP_001451539.1 665 R 331111 CDS YP_001451540.1 157149500 5585815 877..1026 1 NC_009789.1 hypothetical protein 1026 5585815 EcE24377A_B0002 Escherichia coli E24377A hypothetical protein YP_001451540.1 877 D 331111 CDS YP_001451541.1 157149503 5585813 complement(3372..3974) 1 NC_009789.1 identified by match to protein family HMM PF04655; streptomycin resistance protein, StrB 3974 5585813 EcE24377A_B0003 Escherichia coli E24377A streptomycin resistance protein, StrB YP_001451541.1 3372 R 331111 CDS YP_001451542.1 157149502 5585814 complement(4208..5011) 1 NC_009789.1 identified by similarity to SP:P18150; match to protein family HMM PF01636; streptomycin resistance protein, StrA 5011 5585814 EcE24377A_B0004 Escherichia coli E24377A streptomycin resistance protein, StrA YP_001451542.1 4208 R 331111 CDS YP_001451543.1 157149499 5585812 complement(5072..5887) 1 NC_009789.1 sulfonamide resistance mechanism; identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496; dihydropteroate synthase 5887 folP2 5585812 folP2 Escherichia coli E24377A dihydropteroate synthase YP_001451543.1 5072 R 331111 CDS YP_001451544.1 157149552 5585828 complement(1319..1900) 1 NC_009790.1 identified by match to protein family HMM PF04986; IS1294, transposase, truncation 1900 5585828 EcE24377A_E0001 Escherichia coli E24377A IS1294, transposase, truncation YP_001451544.1 1319 R 331111 CDS YP_001451545.1 157149551 5585833 2161..3345 1 NC_009790.1 identified by similarity to GB:CAD31269.1; hypothetical protein 3345 5585833 EcE24377A_E0002 Escherichia coli E24377A hypothetical protein YP_001451545.1 2161 D 331111 CDS YP_001451546.1 157149560 5585840 3514..4191 1 NC_009790.1 identified by match to protein family HMM PF01527; IS66 family orf1 4191 5585840 EcE24377A_E0003 Escherichia coli E24377A IS66 family orf1 YP_001451546.1 3514 D 331111 CDS YP_001451547.1 157149541 5585878 4191..4538 1 NC_009790.1 identified by match to protein family HMM PF05717; IS66 family orf2 4538 5585878 EcE24377A_E0004 Escherichia coli E24377A IS66 family orf2 YP_001451547.1 4191 D 331111 CDS YP_001451548.1 157149509 5585836 4558..6129 1 NC_009790.1 identified by match to protein family HMM PF03050; IS66 family transposase 6129 5585836 EcE24377A_E0005 Escherichia coli E24377A IS66 family transposase YP_001451548.1 4558 D 331111 CDS YP_001451549.1 157149505 5585823 6254..6619 1 NC_009790.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 6619 5585823 EcE24377A_E0006 Escherichia coli E24377A insertion sequence 2 OrfA protein YP_001451549.1 6254 D 331111 CDS YP_001451550.1 157149528 5585893 6577..6828 1 NC_009790.1 IS2, transposase orfB, truncation 6828 5585893 EcE24377A_E0007 Escherichia coli E24377A IS2, transposase orfB, truncation YP_001451550.1 6577 D 331111 CDS YP_001451551.1 157149527 5585875 complement(7009..7182) 1 NC_009790.1 IS91, transposase, truncation 7182 5585875 EcE24377A_E0008 Escherichia coli E24377A IS91, transposase, truncation YP_001451551.1 7009 R 331111 CDS YP_001451552.1 157149518 5585881 complement(7137..7502) 1 NC_009790.1 identified by similarity to GB:AAX22066.1; IS91, orf2 7502 5585881 EcE24377A_E0009 Escherichia coli E24377A IS91, orf2 YP_001451552.1 7137 R 331111 CDS YP_001451553.1 157149529 5585847 complement(7779..8633) 1 NC_009790.1 identified by match to protein family HMM PF04986; IS91, transposase, truncation 8633 5585847 EcE24377A_E0010 Escherichia coli E24377A IS91, transposase, truncation YP_001451553.1 7779 R 331111 CDS YP_001451554.1 157149555 5585877 8644..9912 1 NC_009790.1 identified by similarity to GB:AAR05685.1; hypothetical protein 9912 5585877 EcE24377A_E0011 Escherichia coli E24377A hypothetical protein YP_001451554.1 8644 D 331111 CDS YP_001451555.1 157149506 5585822 9967..10401 1 NC_009790.1 identified by similarity to SP:P10032; match to protein family HMM PF06290; plasmid SOS inhibition protein B 10401 psiB 5585822 psiB Escherichia coli E24377A plasmid SOS inhibition protein B YP_001451555.1 9967 D 331111 CDS YP_001451556.1 157149554 5585851 10398..11117 1 NC_009790.1 PsiA; plasmid SOS inhibition protein A 11117 5585851 EcE24377A_E0013 Escherichia coli E24377A plasmid SOS inhibition protein A YP_001451556.1 10398 D 331111 CDS YP_001451557.1 157149543 5585821 11971..12297 1 NC_009790.1 identified by match to protein family HMM PF01527; IS629, transposase orfA 12297 5585821 EcE24377A_E0014 Escherichia coli E24377A IS629, transposase orfA YP_001451557.1 11971 D 331111 CDS YP_001451558.1 157149565 5585888 13368..14891 1 NC_009790.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388; group II intron-encoded reverse transcriptase/maturase 14891 5585888 EcE24377A_E0016 Escherichia coli E24377A group II intron-encoded reverse transcriptase/maturase YP_001451558.1 13368 D 331111 CDS YP_001451559.1 157149567 5585843 complement(15818..16612) 1 NC_009790.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein 16612 5585843 EcE24377A_E0018 Escherichia coli E24377A IS21 family transposition helper protein YP_001451559.1 15818 R 331111 CDS YP_001451560.1 157149521 5585863 complement(16612..17784) 1 NC_009790.1 identified by similarity to SP:P15025; match to protein family HMM PF00665; IS21 family transposase 17784 5585863 EcE24377A_E0019 Escherichia coli E24377A IS21 family transposase YP_001451560.1 16612 R 331111 CDS YP_001451561.1 157149535 5585838 complement(18516..19442) 1 NC_009790.1 identified by similarity to GB:AAR05668.1; match to protein family HMM PF06924; hypothetical protein 19442 5585838 EcE24377A_E0020 Escherichia coli E24377A hypothetical protein YP_001451561.1 18516 R 331111 CDS YP_001451562.1 157149553 5585853 complement(20027..20998) 1 NC_009790.1 SopB; plasmid-partitioning protein 20998 sopB 5585853 sopB Escherichia coli E24377A plasmid-partitioning protein YP_001451562.1 20027 R 331111 CDS YP_001451563.1 157149534 5585882 complement(20998..22164) 1 NC_009790.1 identified by similarity to SP:P62556; match to protein family HMM PF00376; match to protein family HMM PF01656; plasmid-partitioning protein SopA 22164 sopA 5585882 sopA Escherichia coli E24377A plasmid-partitioning protein SopA YP_001451563.1 20998 R 331111 CDS YP_001451564.1 157149515 5585825 22120..22272 1 NC_009790.1 identified by glimmer; putative; hypothetical protein 22272 5585825 EcE24377A_E0023 Escherichia coli E24377A hypothetical protein YP_001451564.1 22120 D 331111 CDS YP_001451565.1 157149507 5585830 complement(23260..24783) 1 NC_009790.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388; group II intron-encoded reverse transcriptase/maturase 24783 5585830 EcE24377A_E0025 Escherichia coli E24377A group II intron-encoded reverse transcriptase/maturase YP_001451565.1 23260 R 331111 CDS YP_001451566.1 157149561 5585880 complement(25854..26180) 1 NC_009790.1 identified by match to protein family HMM PF01527; IS629, transposase orfA 26180 5585880 EcE24377A_E0027 Escherichia coli E24377A IS629, transposase orfA YP_001451566.1 25854 R 331111 CDS YP_001451567.1 157149549 5585834 27397..28182 1 NC_009790.1 identified by match to protein family HMM PF01555; putative DNA methylase 28182 5585834 EcE24377A_E0028 Escherichia coli E24377A putative DNA methylase YP_001451567.1 27397 D 331111 CDS YP_001451568.1 157149550 5585824 complement(28349..29098) 1 NC_009790.1 identified by glimmer; putative; hypothetical protein 29098 5585824 EcE24377A_E0029 Escherichia coli E24377A hypothetical protein YP_001451568.1 28349 R 331111 CDS YP_001451569.1 157149538 5585831 29124..29264 1 NC_009790.1 identified by glimmer; putative; hypothetical protein 29264 5585831 EcE24377A_E0030 Escherichia coli E24377A hypothetical protein YP_001451569.1 29124 D 331111 CDS YP_001451570.1 157149546 5585826 29643..31004 1 NC_009790.1 identified by glimmer; putative; hypothetical protein 31004 5585826 EcE24377A_E0031 Escherichia coli E24377A hypothetical protein YP_001451570.1 29643 D 331111 CDS YP_001451571.1 157149513 5585861 31051..31614 1 NC_009790.1 identified by glimmer; putative; hypothetical protein 31614 5585861 EcE24377A_E0032 Escherichia coli E24377A hypothetical protein YP_001451571.1 31051 D 331111 CDS YP_001451572.1 157149547 5585829 31654..31779 1 NC_009790.1 identified by glimmer; putative; hypothetical protein 31779 5585829 EcE24377A_E0033 Escherichia coli E24377A hypothetical protein YP_001451572.1 31654 D 331111 CDS YP_001451573.1 157149537 5585818 32838..33659 1 NC_009790.1 identified by similarity to GB:CAI07494.1; match to protein family HMM PF06067; hypothetical protein 33659 5585818 EcE24377A_E0034 Escherichia coli E24377A hypothetical protein YP_001451573.1 32838 D 331111 CDS YP_001451574.1 157149559 5585866 complement(34347..35141) 1 NC_009790.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein 35141 5585866 EcE24377A_E0035 Escherichia coli E24377A IS21 family transposition helper protein YP_001451574.1 34347 R 331111 CDS YP_001451575.1 157149531 5585879 complement(35141..36313) 1 NC_009790.1 identified by similarity to SP:P15025; match to protein family HMM PF00665; IS21 family transposase 36313 5585879 EcE24377A_E0036 Escherichia coli E24377A IS21 family transposase YP_001451575.1 35141 R 331111 CDS YP_001451576.1 157149557 5585884 complement(36400..36750) 1 NC_009790.1 hypothetical protein 36750 5585884 EcE24377A_E0037 Escherichia coli E24377A hypothetical protein YP_001451576.1 36400 R 331111 CDS YP_001451577.1 157149568 5585867 complement(38653..40191) 1 NC_009790.1 identified by match to protein family HMM PF03050; IS66 family transposase 40191 5585867 EcE24377A_E0038 Escherichia coli E24377A IS66 family transposase YP_001451577.1 38653 R 331111 CDS YP_001451578.1 157149566 5585864 complement(40241..40588) 1 NC_009790.1 identified by match to protein family HMM PF05717; IS66 family orf2 40588 5585864 EcE24377A_E0039 Escherichia coli E24377A IS66 family orf2 YP_001451578.1 40241 R 331111 CDS YP_001451579.1 157149511 5585859 complement(40585..40974) 1 NC_009790.1 identified by match to protein family HMM PF01527; IS66 family orf1 40974 5585859 EcE24377A_E0040 Escherichia coli E24377A IS66 family orf1 YP_001451579.1 40585 R 331111 CDS YP_001451580.1 157149532 5585854 41789..42154 1 NC_009790.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 42154 5585854 EcE24377A_E0041 Escherichia coli E24377A insertion sequence 2 OrfA protein YP_001451580.1 41789 D 331111 CDS YP_001451581.1 157149536 5585869 42112..43023 1 NC_009790.1 identified by similarity to SP:P51026; match to protein family HMM PF00665; IS2, transposase orfB 43023 5585869 EcE24377A_E0042 Escherichia coli E24377A IS2, transposase orfB YP_001451581.1 42112 D 331111 CDS YP_001451582.1 157149525 5585885 43189..43461 1 NC_009790.1 identified by match to protein family HMM PF03811; IS1, transposase orfA 43461 5585885 EcE24377A_E0043 Escherichia coli E24377A IS1, transposase orfA YP_001451582.1 43189 D 331111 CDS YP_001451583.1 157149516 5585890 43488..43883 1 NC_009790.1 identified by match to protein family HMM PF03400; IS1, transposase orfB 43883 5585890 EcE24377A_E0044 Escherichia coli E24377A IS1, transposase orfB YP_001451583.1 43488 D 331111 CDS YP_001451584.1 157149569 5585835 44240..44917 1 NC_009790.1 identified by match to protein family HMM PF01527; IS66 family orf1 44917 5585835 EcE24377A_E0045 Escherichia coli E24377A IS66 family orf1 YP_001451584.1 44240 D 331111 CDS YP_001451585.1 157149526 5585871 44917..45264 1 NC_009790.1 identified by match to protein family HMM PF05717; IS66 family orf2 45264 5585871 EcE24377A_E0046 Escherichia coli E24377A IS66 family orf2 YP_001451585.1 44917 D 331111 CDS YP_001451586.1 157149558 5585876 45284..46855 1 NC_009790.1 identified by match to protein family HMM PF03050; IS66 family transposase 46855 5585876 EcE24377A_E0047 Escherichia coli E24377A IS66 family transposase YP_001451586.1 45284 D 331111 CDS YP_001451587.1 157149572 5585817 complement(47535..47810) 1 NC_009790.1 identified by match to protein family HMM PF03811; IS1, transposase orfA 47810 5585817 EcE24377A_E0049 Escherichia coli E24377A IS1, transposase orfA YP_001451587.1 47535 R 331111 CDS YP_001451588.1 157149562 5585855 49306..53406 1 NC_009790.1 identified by similarity to SP:Q84GK0; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; secreted serine peptidase EatA 53406 eatA 5585855 eatA Escherichia coli E24377A secreted serine peptidase EatA YP_001451588.1 49306 D 331111 CDS YP_001451589.1 157149523 5585874 complement(53749..54471) 1 NC_009790.1 identified by similarity to SP:P76135; match to protein family HMM PF00165; HTH-type transcriptional regulator YdeO 54471 ydeO 5585874 ydeO Escherichia coli E24377A HTH-type transcriptional regulator YdeO YP_001451589.1 53749 R 331111 CDS YP_001451590.1 157149510 5585837 54701..55381 1 NC_009790.1 identified by match to protein family HMM PF00563; EAL domain-containing protein 55381 5585837 EcE24377A_E0053 Escherichia coli E24377A EAL domain-containing protein YP_001451590.1 54701 D 331111 CDS YP_001451591.1 157149522 5585858 complement(55821..56462) 1 NC_009790.1 identified by match to protein family HMM PF00239; resolvase domain-containing protein 56462 5585858 EcE24377A_E0054 Escherichia coli E24377A resolvase domain-containing protein YP_001451591.1 55821 R 331111 CDS YP_001451592.1 157149514 5585883 complement(56792..57505) 1 NC_009790.1 identified by similarity to SP:P06615; match to protein family HMM PF00589; resolvase 57505 resD 5585883 resD Escherichia coli E24377A resolvase YP_001451592.1 56792 R 331111 CDS YP_001451593.1 157149570 5585827 complement(57506..57811) 1 NC_009790.1 controlled cell death protein; post-segregation toxin; toxin addiction system; plasmid maintenance protein CcdB 57811 ccdB2 5585827 ccdB2 Escherichia coli E24377A plasmid maintenance protein CcdB YP_001451593.1 57506 R 331111 CDS YP_001451594.2 229220658 5585873 complement(57813..58031) 1 NC_009790.1 identified by similarity to SP:P62552; match to protein family HMM PF07362; plasmid maintenance protein CcdA 58031 ccdA1 5585873 ccdA1 Escherichia coli E24377A plasmid maintenance protein CcdA YP_001451594.2 57813 R 331111 CDS YP_001451595.1 157149533 5585849 58476..58733 1 NC_009790.1 identified by similarity to GB:AAZ89279.1; hypothetical protein 58733 5585849 EcE24377A_E0058 Escherichia coli E24377A hypothetical protein YP_001451595.1 58476 D 331111 CDS YP_001451596.1 157149520 5585857 58733..59263 1 NC_009790.1 identified by similarity to GB:AAZ89280.1; hypothetical protein 59263 5585857 EcE24377A_E0059 Escherichia coli E24377A hypothetical protein YP_001451596.1 58733 D 331111 CDS YP_001451597.1 157149519 5585848 59528..60349 1 NC_009790.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase family protein 60349 5585848 EcE24377A_E0060 Escherichia coli E24377A polysaccharide deacetylase family protein YP_001451597.1 59528 D 331111 CDS YP_001451598.1 157149517 5585845 60352..61440 1 NC_009790.1 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 61440 5585845 EcE24377A_E0061 Escherichia coli E24377A glycosyl transferase, group 1 family protein YP_001451598.1 60352 D 331111 CDS YP_001451599.1 157149530 5585891 61445..62395 1 NC_009790.1 identified by match to protein family HMM PF04393; hypothetical protein 62395 5585891 EcE24377A_E0063 Escherichia coli E24377A hypothetical protein YP_001451599.1 61445 D 331111 CDS YP_001451600.1 157149545 5585887 complement(62340..62453) 1 NC_009790.1 identified by glimmer; putative; hypothetical protein 62453 5585887 EcE24377A_E0062 Escherichia coli E24377A hypothetical protein YP_001451600.1 62340 R 331111 CDS YP_001451601.1 157149508 5585819 complement(63467..63685) 1 NC_009790.1 IS630, transposase, truncation 63685 5585819 EcE24377A_E0065 Escherichia coli E24377A IS630, transposase, truncation YP_001451601.1 63467 R 331111 CDS YP_001451602.1 157149540 5585832 complement(64940..65209) 1 NC_009790.1 IS1294, transposase, truncation 65209 5585832 EcE24377A_E0066 Escherichia coli E24377A IS1294, transposase, truncation YP_001451602.1 64940 R 331111 CDS YP_001451603.1 157149542 5585860 complement(65257..66795) 1 NC_009790.1 identified by match to protein family HMM PF03050; IS66 family transposase 66795 5585860 EcE24377A_E0068 Escherichia coli E24377A IS66 family transposase YP_001451603.1 65257 R 331111 CDS YP_001451604.1 157149564 5585844 complement(66845..67192) 1 NC_009790.1 identified by match to protein family HMM PF05717; IS66 family orf2 67192 5585844 EcE24377A_E0069 Escherichia coli E24377A IS66 family orf2 YP_001451604.1 66845 R 331111 CDS YP_001451605.1 157149512 5585868 complement(67189..67578) 1 NC_009790.1 identified by match to protein family HMM PF01527; IS66 family element 67578 5585868 EcE24377A_E0070 Escherichia coli E24377A IS66 family element YP_001451605.1 67189 R 331111 CDS YP_001451606.1 157149539 5585872 67666..67791 1 NC_009790.1 identified by glimmer; putative; hypothetical protein 67791 5585872 EcE24377A_E0072 Escherichia coli E24377A hypothetical protein YP_001451606.1 67666 D 331111 CDS YP_001451607.1 157149573 5585870 complement(67684..67782) 1 NC_009790.1 identified by glimmer; putative; hypothetical protein 67782 5585870 EcE24377A_E0071 Escherichia coli E24377A hypothetical protein YP_001451607.1 67684 R 331111 CDS YP_001451608.1 157149571 5585852 67898..68257 1 NC_009790.1 identified by similarity to SP:P12060; match to protein family HMM PF05513; match to protein family HMM TIGR02758; type IV conjugative transfer system pilin TraA 68257 traA 5585852 traA Escherichia coli E24377A type IV conjugative transfer system pilin TraA YP_001451608.1 67898 D 331111 CDS YP_001451609.1 157149524 5585862 68259..68564 1 NC_009790.1 identified by similarity to SP:P12058; match to protein family HMM PF07178; match to protein family HMM TIGR02762; conjugal transfer pilus assembly protein TraL 68564 traL 5585862 traL Escherichia coli E24377A conjugal transfer pilus assembly protein TraL YP_001451609.1 68259 D 331111 CDS YP_001451610.1 157149544 5585850 68584..69147 1 NC_009790.1 identified by similarity to SP:P12057; match to protein family HMM PF05309; match to protein family HMM TIGR02761; conjugal transfer pilus assembly protein TraE 69147 traE 5585850 traE Escherichia coli E24377A conjugal transfer pilus assembly protein TraE YP_001451610.1 68584 D 331111 CDS YP_001451611.1 157149556 5585842 69460..71505 1 NC_009790.1 identified by match to protein family HMM PF07057; match to protein family HMM TIGR02759; putative type IV conjugative transfer system coupling protein TraD 71505 5585842 EcE24377A_E0076 Escherichia coli E24377A putative type IV conjugative transfer system coupling protein TraD YP_001451611.1 69460 D 331111 CDS YP_001451612.1 157149563 5585892 71532..71915 1 NC_009790.1 identified by match to protein family HMM TIGR02755; type-F conjugative transfer system pilin acetylase TraX, truncation 71915 5585892 EcE24377A_E0077 Escherichia coli E24377A type-F conjugative transfer system pilin acetylase TraX, truncation YP_001451612.1 71532 D 331111 CDS YP_001451613.1 157149576 5585895 complement(1408..1503) 1 NC_009791.1 identified by glimmer; putative; hypothetical protein 1503 5585895 EcE24377A_A0001 Escherichia coli E24377A hypothetical protein YP_001451613.1 1408 R 331111 CDS YP_001451614.1 157149577 5585894 2674..2895 1 NC_009791.1 identified by glimmer; putative; hypothetical protein 2895 5585894 EcE24377A_A0002 Escherichia coli E24377A hypothetical protein YP_001451614.1 2674 D 331111 CDS YP_001451615.1 157149575 5585896 complement(2984..4549) 1 NC_009791.1 identified by match to protein family HMM PF03432; mobilization protein MobA 4549 5585896 EcE24377A_A0003 Escherichia coli E24377A mobilization protein MobA YP_001451615.1 2984 R 331111 CDS YP_001461170.1 157158747 5588161 336..2798 1 NC_009801.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 2798 thrA 5588161 thrA Escherichia coli E24377A bifunctional aspartokinase I/homoserine dehydrogenase I YP_001461170.1 336 D 331111 CDS YP_001461171.1 157158096 5589520 2800..3732 1 NC_009801.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 3732 thrB 5589520 thrB Escherichia coli E24377A homoserine kinase YP_001461171.1 2800 D 331111 CDS YP_001461172.1 157157451 5590225 3733..5019 1 NC_009801.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 5019 thrC 5590225 thrC Escherichia coli E24377A threonine synthase YP_001461172.1 3733 D 331111 CDS YP_001461173.1 157156558 5589339 complement(5309..5806) 1 NC_009801.1 identified by glimmer; hypothetical protein 5806 5589339 EcE24377A_0004 Escherichia coli E24377A hypothetical protein YP_001461173.1 5309 R 331111 CDS YP_001461174.1 157156183 5588870 5789..6769 1 NC_009801.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 6769 5588870 EcE24377A_0005 Escherichia coli E24377A IS621, transposase YP_001461174.1 5789 D 331111 CDS YP_001461175.1 157155229 5589270 complement(6961..7737) 1 NC_009801.1 identified by similarity to SP:Q8ZS17; match to protein family HMM PF03883; hypothetical protein 7737 5589270 EcE24377A_0006 Escherichia coli E24377A hypothetical protein YP_001461175.1 6961 R 331111 CDS YP_001461176.1 157154855 5589335 complement(7807..9237) 1 NC_009801.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; amino acid carrier protein 9237 agcS 5589335 agcS Escherichia coli E24377A amino acid carrier protein YP_001461176.1 7807 R 331111 CDS YP_001461177.1 157158697 5588812 9516..10469 1 NC_009801.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874; transaldolase B 10469 tal2 5588812 tal2 Escherichia coli E24377A transaldolase B YP_001461177.1 9516 D 331111 CDS YP_001461178.1 157158038 5589183 10584..11171 1 NC_009801.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 11171 mogA 5589183 mogA Escherichia coli E24377A molybdenum cofactor biosynthesis protein MogA YP_001461178.1 10584 D 331111 CDS YP_001461179.1 157157506 5586648 complement(11206..11772) 1 NC_009801.1 identified by match to protein family HMM PF01184; hypothetical protein 11772 5586648 EcE24377A_0010 Escherichia coli E24377A hypothetical protein YP_001461179.1 11206 R 331111 CDS YP_001461180.1 157156853 5588148 complement(11921..12634) 1 NC_009801.1 identified by match to protein family HMM PF03667; hypothetical protein 12634 5588148 EcE24377A_0011 Escherichia coli E24377A hypothetical protein YP_001461180.1 11921 R 331111 CDS YP_001461181.1 157157943 5588138 complement(12660..13064) 1 NC_009801.1 hypothetical protein 13064 5588138 EcE24377A_0012 Escherichia coli E24377A hypothetical protein YP_001461181.1 12660 R 331111 CDS YP_001461182.1 157157283 5589574 complement(13199..13348) 1 NC_009801.1 identified by glimmer; hypothetical protein 13348 5589574 EcE24377A_0013 Escherichia coli E24377A hypothetical protein YP_001461182.1 13199 R 331111 CDS YP_001461183.1 157159098 5590429 13441..15357 1 NC_009801.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 15357 dnaK 5590429 dnaK Escherichia coli E24377A molecular chaperone DnaK YP_001461183.1 13441 D 331111 CDS YP_001461184.1 157156432 5588207 15446..16576 1 NC_009801.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 16576 dnaJ 5588207 dnaJ Escherichia coli E24377A molecular chaperone DnaJ YP_001461184.1 15446 D 331111 CDS YP_001461185.1 157155398 5589884 17418..18584 1 NC_009801.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 18584 nhaA 5589884 nhaA Escherichia coli E24377A pH-dependent sodium/proton antiporter YP_001461185.1 17418 D 331111 CDS YP_001461186.1 157158018 5586221 18650..19549 1 NC_009801.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 19549 nhaR 5586221 nhaR Escherichia coli E24377A transcriptional activator NhaR YP_001461186.1 18650 D 331111 CDS YP_001461187.1 157157508 5588977 complement(19588..20547) 1 NC_009801.1 identified by similarity to GB:AAZ86820.1; hypothetical protein 20547 5588977 EcE24377A_0018 Escherichia coli E24377A hypothetical protein YP_001461187.1 19588 R 331111 CDS YP_001461188.1 157159091 5588619 complement(22138..23460) 1 NC_009801.1 identified by glimmer; hypothetical protein 23460 5588619 EcE24377A_0020 Escherichia coli E24377A hypothetical protein YP_001461188.1 22138 R 331111 CDS YP_001461189.1 157157495 5590352 23481..23585 1 NC_009801.1 identified by glimmer; hypothetical protein 23585 5590352 EcE24377A_0021 Escherichia coli E24377A hypothetical protein YP_001461189.1 23481 D 331111 CDS YP_001461190.1 157158047 5588802 complement(23844..24008) 1 NC_009801.1 identified by glimmer; hypothetical protein 24008 5588802 EcE24377A_0022 Escherichia coli E24377A hypothetical protein YP_001461190.1 23844 R 331111 CDS YP_001461191.1 157156490 5586086 complement(24030..24293) 1 NC_009801.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 24293 rpsT 5586086 rpsT Escherichia coli E24377A 30S ribosomal protein S20 YP_001461191.1 24030 R 331111 CDS YP_001461192.1 157156024 5590625 24396..24614 1 NC_009801.1 identified by similarity to GB:AAZ86826.1; hypothetical protein 24614 5590625 EcE24377A_0024 Escherichia coli E24377A hypothetical protein YP_001461192.1 24396 D 331111 CDS YP_001461193.1 157156528 5587150 24622..25563 1 NC_009801.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 25563 ribF 5587150 ribF Escherichia coli E24377A bifunctional riboflavin kinase/FMN adenylyltransferase YP_001461193.1 24622 D 331111 CDS YP_001461194.1 157154999 5587280 25606..28422 1 NC_009801.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 28422 ileS 5587280 ileS Escherichia coli E24377A isoleucyl-tRNA synthetase YP_001461194.1 25606 D 331111 CDS YP_001461195.1 157155523 5586401 28422..28916 1 NC_009801.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 28916 lspA 5586401 lspA Escherichia coli E24377A lipoprotein signal peptidase YP_001461195.1 28422 D 331111 CDS YP_001461196.1 157158699 5586012 29021..29470 1 NC_009801.1 identified by match to protein family HMM PF00254; FKBP-type peptidylprolyl isomerase 29470 fkpB 5586012 fkpB Escherichia coli E24377A FKBP-type peptidylprolyl isomerase YP_001461196.1 29021 D 331111 CDS YP_001461197.1 157155637 5589185 29472..30422 1 NC_009801.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 30422 ispH 5589185 ispH Escherichia coli E24377A 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_001461197.1 29472 D 331111 CDS YP_001461198.1 157156462 5589098 30488..31402 1 NC_009801.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 31402 rihC 5589098 rihC Escherichia coli E24377A ribonucleoside hydrolase RihC YP_001461198.1 30488 D 331111 CDS YP_001461199.1 157156976 5585997 31569..32390 1 NC_009801.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 32390 dapB 5585997 dapB Escherichia coli E24377A dihydrodipicolinate reductase YP_001461199.1 31569 D 331111 CDS YP_001461200.1 157157922 5588786 complement(32633..32728) 1 NC_009801.1 hypothetical protein 32728 5588786 EcE24377A_0032 Escherichia coli E24377A hypothetical protein YP_001461200.1 32633 R 331111 CDS YP_001461201.1 157158284 5586508 32846..33994 1 NC_009801.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 33994 carA 5586508 carA Escherichia coli E24377A carbamoyl phosphate synthase small subunit YP_001461201.1 32846 D 331111 CDS YP_001461202.1 157159012 5588649 34012..37233 1 NC_009801.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 37233 carB 5588649 carB Escherichia coli E24377A carbamoyl phosphate synthase large subunit YP_001461202.1 34012 D 331111 CDS YP_001461203.1 157155216 5588862 complement(37241..37459) 1 NC_009801.1 identified by glimmer; hypothetical protein 37459 5588862 EcE24377A_0035 Escherichia coli E24377A hypothetical protein YP_001461203.1 37241 R 331111 CDS YP_001461204.1 157155895 5586841 37494..37889 1 NC_009801.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 37889 caiF 5586841 caiF Escherichia coli E24377A DNA-binding transcriptional activator CaiF YP_001461204.1 37494 D 331111 CDS YP_001461205.1 157156306 5587319 complement(37975..38565) 1 NC_009801.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE 38565 caiE 5587319 caiE Escherichia coli E24377A carnitine operon protein CaiE YP_001461205.1 37975 R 331111 CDS YP_001461206.2 229220661 5587267 complement(38571..39356) 1 NC_009801.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase 39356 caiD 5587267 caiD Escherichia coli E24377A carnitinyl-CoA dehydratase YP_001461206.2 38571 R 331111 CDS YP_001461207.1 157155167 5588976 complement(39465..41033) 1 NC_009801.1 identified by match to protein family HMM PF00501; crotonobetaine/carnitine-CoA ligase 41033 caiC 5588976 caiC Escherichia coli E24377A crotonobetaine/carnitine-CoA ligase YP_001461207.1 39465 R 331111 CDS YP_001461208.1 157156920 5590821 complement(41092..42309) 1 NC_009801.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase 42309 caiB 5590821 caiB Escherichia coli E24377A crotonobetainyl-CoA:carnitine CoA-transferase YP_001461208.1 41092 R 331111 CDS YP_001461209.1 157156236 5590267 complement(42438..43580) 1 NC_009801.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase 43580 caiA 5590267 caiA Escherichia coli E24377A crotonobetainyl-CoA dehydrogenase YP_001461209.1 42438 R 331111 CDS YP_001461210.1 157157828 5586104 complement(43611..45125) 1 NC_009801.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter 45125 caiT 5586104 caiT Escherichia coli E24377A L-carnitine/gamma-butyrobetaine antiporter YP_001461210.1 43611 R 331111 CDS YP_001461211.1 157159271 5586268 45140..45241 1 NC_009801.1 identified by glimmer; hypothetical protein 45241 5586268 EcE24377A_0043 Escherichia coli E24377A hypothetical protein YP_001461211.1 45140 D 331111 CDS YP_001461212.1 157159020 5589593 45420..45530 1 NC_009801.1 identified by similarity to GB:AAX63975.1; hypothetical protein 45530 5589593 EcE24377A_0044 Escherichia coli E24377A hypothetical protein YP_001461212.1 45420 D 331111 CDS YP_001461213.1 157158533 5589423 45599..46369 1 NC_009801.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 46369 etfB 5589423 etfB Escherichia coli E24377A electron transfer flavoprotein FixA YP_001461213.1 45599 D 331111 CDS YP_001461214.1 157155244 5587416 46384..47325 1 NC_009801.1 involved in electron transfer during carnitine metabolism; electron transfer flavoprotein FixB 47325 fixB 5587416 fixB Escherichia coli E24377A electron transfer flavoprotein FixB YP_001461214.1 46384 D 331111 CDS YP_001461215.1 157156667 5586155 47376..48662 1 NC_009801.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 48662 fixC 5586155 fixC Escherichia coli E24377A oxidoreductase FixC YP_001461215.1 47376 D 331111 CDS YP_001461216.1 157156329 5588599 48659..48946 1 NC_009801.1 ferredoxin-like protein FixX 48946 fixX 5588599 fixX Escherichia coli E24377A ferredoxin-like protein FixX YP_001461216.1 48659 D 331111 CDS YP_001461217.1 157154973 5590819 49004..50335 1 NC_009801.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator family transporter 50335 5590819 EcE24377A_0049 Escherichia coli E24377A major facilitator family transporter YP_001461217.1 49004 D 331111 CDS YP_001461218.1 157155009 5589117 50443..50973 1 NC_009801.1 Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 50973 kefF 5589117 kefF Escherichia coli E24377A glutathione-regulated potassium-efflux system ancillary protein KefF YP_001461218.1 50443 D 331111 CDS YP_001461219.1 157159263 5590837 50966..52828 1 NC_009801.1 transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 52828 kefC 5590837 kefC Escherichia coli E24377A glutathione-regulated potassium-efflux system protein KefC YP_001461219.1 50966 D 331111 CDS YP_001461220.1 157158756 5587884 53020..53499 1 NC_009801.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 53499 folA 5587884 folA Escherichia coli E24377A dihydrofolate reductase YP_001461220.1 53020 D 331111 CDS YP_001461221.1 157158228 5586714 complement(53577..54419) 1 NC_009801.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 54419 apaH 5586714 apaH Escherichia coli E24377A diadenosine tetraphosphatase YP_001461221.1 53577 R 331111 CDS YP_001461222.1 157157398 5587798 complement(54426..54803) 1 NC_009801.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 54803 apaG 5587798 apaG Escherichia coli E24377A ApaG protein YP_001461222.1 54426 R 331111 CDS YP_001461223.1 157156598 5589509 complement(54806..55627) 1 NC_009801.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 55627 ksgA 5589509 ksgA Escherichia coli E24377A dimethyladenosine transferase YP_001461223.1 54806 R 331111 CDS YP_001461224.1 157156948 5586267 complement(55624..56613) 1 NC_009801.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 56613 pdxA 5586267 pdxA Escherichia coli E24377A 4-hydroxythreonine-4-phosphate dehydrogenase YP_001461224.1 55624 R 331111 CDS YP_001461225.1 157155530 5590250 complement(56613..57899) 1 NC_009801.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA 57899 surA 5590250 surA Escherichia coli E24377A peptidyl-prolyl cis-trans isomerase SurA YP_001461225.1 56613 R 331111 CDS YP_001461226.1 157155793 5586004 complement(57952..60306) 1 NC_009801.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 60306 imp 5586004 imp Escherichia coli E24377A organic solvent tolerance protein YP_001461226.1 57952 R 331111 CDS YP_001461227.1 157158680 5587614 60561..61376 1 NC_009801.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 61376 djlA 5587614 djlA Escherichia coli E24377A Dna-J like membrane chaperone protein YP_001461227.1 60561 D 331111 CDS YP_001461228.1 157159461 5586538 complement(61493..62152) 1 NC_009801.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A 62152 5586538 EcE24377A_0060 Escherichia coli E24377A 23S rRNA/tRNA pseudouridine synthase A YP_001461228.1 61493 R 331111 CDS YP_001461229.1 157157613 5590175 complement(62164..65070) 1 NC_009801.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 65070 rapA 5590175 rapA Escherichia coli E24377A ATP-dependent helicase HepA YP_001461229.1 62164 R 331111 CDS YP_001461230.1 157156108 5590669 complement(65235..67586) 1 NC_009801.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II 67586 polB 5590669 polB Escherichia coli E24377A DNA polymerase II YP_001461230.1 65235 R 331111 CDS YP_001461231.1 157154722 5590176 complement(67661..68356) 1 NC_009801.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 68356 araD 5590176 araD Escherichia coli E24377A L-ribulose-5-phosphate 4-epimerase YP_001461231.1 67661 R 331111 CDS YP_001461232.1 157155370 5586876 complement(68525..70027) 1 NC_009801.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 70027 araA 5586876 araA Escherichia coli E24377A L-arabinose isomerase YP_001461232.1 68525 R 331111 CDS YP_001461233.1 157158411 5587106 complement(70038..71738) 1 NC_009801.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 71738 araB 5587106 araB Escherichia coli E24377A ribulokinase YP_001461233.1 70038 R 331111 CDS YP_001461234.1 157159441 5589356 72077..72955 1 NC_009801.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 72955 araC 5589356 araC Escherichia coli E24377A DNA-binding transcriptional regulator AraC YP_001461234.1 72077 D 331111 CDS YP_001461235.1 157159410 5587008 73041..73805 1 NC_009801.1 identified by similarity to SP:P30149; match to protein family HMM PF09335; hypothetical protein 73805 5587008 EcE24377A_0067 Escherichia coli E24377A hypothetical protein YP_001461235.1 73041 D 331111 CDS YP_001461236.1 157157436 5588388 complement(73919..74617) 1 NC_009801.1 with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit 74617 thiQ 5588388 thiQ Escherichia coli E24377A thiamine transporter ATP-binding subunit YP_001461236.1 73919 R 331111 CDS YP_001461237.1 157157490 5590217 complement(74601..76211) 1 NC_009801.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 76211 thiP 5590217 thiP Escherichia coli E24377A thiamine transporter membrane protein YP_001461237.1 74601 R 331111 CDS YP_001461238.1 157159051 5590754 complement(76187..77170) 1 NC_009801.1 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 77170 tbpA 5590754 tbpA Escherichia coli E24377A thiamine transporter substrate binding subunit YP_001461238.1 76187 R 331111 CDS YP_001461239.1 157158860 5588848 complement(77214..77333) 1 NC_009801.1 lipoprotein 77333 5588848 EcE24377A_0071 Escherichia coli E24377A lipoprotein YP_001461239.1 77214 R 331111 CDS YP_001461240.1 157155626 5587479 complement(77334..78989) 1 NC_009801.1 activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR 78989 sgrR 5587479 sgrR Escherichia coli E24377A transcriptional regulator SgrR YP_001461240.1 77334 R 331111 CDS YP_001461241.1 157156264 5590260 79311..80489 1 NC_009801.1 identified by similarity to SP:P31675; match to protein family HMM PF07690; match to protein family HMM TIGR00899; major facilitator superfamily sugar transporter 80489 setA 5590260 setA Escherichia coli E24377A major facilitator superfamily sugar transporter YP_001461241.1 79311 D 331111 CDS YP_001461242.1 157158235 5588756 complement(80538..81143) 1 NC_009801.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 81143 leuD 5588756 leuD Escherichia coli E24377A isopropylmalate isomerase small subunit YP_001461242.1 80538 R 331111 CDS YP_001461243.1 157157583 5587213 complement(81154..82554) 1 NC_009801.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 82554 leuC 5587213 leuC Escherichia coli E24377A isopropylmalate isomerase large subunit YP_001461243.1 81154 R 331111 CDS YP_001461244.1 157157195 5589971 complement(82557..83648) 1 NC_009801.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 83648 leuB 5589971 leuB Escherichia coli E24377A 3-isopropylmalate dehydrogenase YP_001461244.1 82557 R 331111 CDS YP_001461245.1 157159154 5590425 complement(83648..85219) 1 NC_009801.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 85219 leuA 5590425 leuA Escherichia coli E24377A 2-isopropylmalate synthase YP_001461245.1 83648 R 331111 CDS YP_001461246.1 157158356 5588252 86058..87002 1 NC_009801.1 activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 87002 leuO 5588252 leuO Escherichia coli E24377A leucine transcriptional activator YP_001461246.1 86058 D 331111 CDS YP_001461247.1 157157875 5587843 87320..89044 1 NC_009801.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 89044 ilvI 5587843 ilvI Escherichia coli E24377A acetolactate synthase 3 catalytic subunit YP_001461247.1 87320 D 331111 CDS YP_001461248.1 157157377 5586249 89047..89538 1 NC_009801.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 89538 ilvH 5586249 ilvH Escherichia coli E24377A acetolactate synthase 3 regulatory subunit YP_001461248.1 89047 D 331111 CDS YP_001461249.1 157158931 5586100 89590..89721 1 NC_009801.1 identified by glimmer; hypothetical protein 89721 5586100 EcE24377A_0081 Escherichia coli E24377A hypothetical protein YP_001461249.1 89590 D 331111 CDS YP_001461250.1 157155442 5588519 89718..90722 1 NC_009801.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 90722 fruR 5588519 fruR Escherichia coli E24377A DNA-binding transcriptional regulator FruR YP_001461250.1 89718 D 331111 CDS YP_001461251.1 157155426 5588249 91324..91782 1 NC_009801.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 91782 mraZ 5588249 mraZ Escherichia coli E24377A cell division protein MraZ YP_001461251.1 91324 D 331111 CDS YP_001461252.1 157154775 5588283 91784..92725 1 NC_009801.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 92725 mraW 5588283 mraW Escherichia coli E24377A S-adenosyl-methyltransferase MraW YP_001461252.1 91784 D 331111 CDS YP_001461253.1 157156813 5586705 92722..93087 1 NC_009801.1 membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 93087 ftsL 5586705 ftsL Escherichia coli E24377A cell division protein FtsL YP_001461253.1 92722 D 331111 CDS YP_001461254.1 157158087 5587071 93103..94869 1 NC_009801.1 identified by similarity to SP:P0AD68; match to protein family HMM PF00905; match to protein family HMM PF03717; peptidoglycan synthetase FtsI 94869 ftsI 5587071 ftsI Escherichia coli E24377A peptidoglycan synthetase FtsI YP_001461254.1 93103 D 331111 CDS YP_001461255.1 157159417 5588782 94856..96343 1 NC_009801.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 96343 murE 5588782 murE Escherichia coli E24377A UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_001461255.1 94856 D 331111 CDS YP_001461256.1 157158796 5590344 96340..97698 1 NC_009801.1 identified by similarity to SP:P11880; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 97698 murF 5590344 murF Escherichia coli E24377A UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_001461256.1 96340 D 331111 CDS YP_001461257.1 157158057 5588595 97692..98774 1 NC_009801.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 98774 mraY 5588595 mraY Escherichia coli E24377A phospho-N-acetylmuramoyl-pentapeptide- transferase YP_001461257.1 97692 D 331111 CDS YP_001461258.1 157156086 5586940 98777..100093 1 NC_009801.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 100093 murD 5586940 murD Escherichia coli E24377A UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_001461258.1 98777 D 331111 CDS YP_001461259.1 157156576 5587083 100093..101337 1 NC_009801.1 integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 101337 ftsW 5587083 ftsW Escherichia coli E24377A cell division protein FtsW YP_001461259.1 100093 D 331111 CDS YP_001461260.1 157154968 5587512 101334..102401 1 NC_009801.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 102401 murG 5587512 murG Escherichia coli E24377A undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_001461260.1 101334 D 331111 CDS YP_001461261.1 157154862 5589461 102455..103930 1 NC_009801.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 103930 murC 5589461 murC Escherichia coli E24377A UDP-N-acetylmuramate--L-alanine ligase YP_001461261.1 102455 D 331111 CDS YP_001461262.1 157155564 5589930 103923..104843 1 NC_009801.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 104843 ddl 5589930 ddl Escherichia coli E24377A D-alanine--D-alanine ligase YP_001461262.1 103923 D 331111 CDS YP_001461263.1 157159455 5589903 104845..105675 1 NC_009801.1 involved in septum formation; cell division protein FtsQ 105675 ftsQ 5589903 ftsQ Escherichia coli E24377A cell division protein FtsQ YP_001461263.1 104845 D 331111 CDS YP_001461264.1 157157630 5587153 105672..106934 1 NC_009801.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 106934 ftsA 5587153 ftsA Escherichia coli E24377A cell division protein FtsA YP_001461264.1 105672 D 331111 CDS YP_001461265.1 157156227 5589773 106995..108146 1 NC_009801.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 108146 ftsZ 5589773 ftsZ Escherichia coli E24377A cell division protein FtsZ YP_001461265.1 106995 D 331111 CDS YP_001461266.1 157156686 5586963 108247..109164 1 NC_009801.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 109164 lpxC 5586963 lpxC Escherichia coli E24377A UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_001461266.1 108247 D 331111 CDS YP_001461267.1 157155208 5587410 109320..109907 1 NC_009801.1 secM translational pause allows for the initiation of secA translation; SecA regulator SecM 109907 secM 5587410 secM Escherichia coli E24377A SecA regulator SecM YP_001461267.1 109320 D 331111 CDS YP_001461268.1 157156803 5587476 109969..112674 1 NC_009801.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 112674 secA 5587476 secA Escherichia coli E24377A preprotein translocase subunit SecA YP_001461268.1 109969 D 331111 CDS YP_001461269.1 157156268 5587704 112734..113123 1 NC_009801.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586; nucleoside triphosphate pyrophosphohydrolase 113123 mutT 5587704 mutT Escherichia coli E24377A nucleoside triphosphate pyrophosphohydrolase YP_001461269.1 112734 D 331111 CDS YP_001461270.1 157155884 5588446 complement(113138..113251) 1 NC_009801.1 identified by similarity to GB:AAZ86903.1; hypothetical protein 113251 5588446 EcE24377A_0102 Escherichia coli E24377A hypothetical protein YP_001461270.1 113138 R 331111 CDS YP_001461271.1 157155357 5587966 complement(113223..113420) 1 NC_009801.1 identified by similarity to SP:P0A8H8; match to protein family HMM PF03884; zinc-binding protein 113420 5587966 EcE24377A_0103 Escherichia coli E24377A zinc-binding protein YP_001461271.1 113223 R 331111 CDS YP_001461272.1 157156967 5589216 complement(113430..114173) 1 NC_009801.1 identified by match to protein family HMM PF07072; hypothetical protein 114173 5589216 EcE24377A_0104 Escherichia coli E24377A hypothetical protein YP_001461272.1 113430 R 331111 CDS YP_001461273.1 157156454 5590083 complement(114173..114793) 1 NC_009801.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 114793 coaE 5590083 coaE Escherichia coli E24377A dephospho-CoA kinase YP_001461273.1 114173 R 331111 CDS YP_001461274.1 157158521 5589315 115018..116061 1 NC_009801.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 116061 guaC 5589315 guaC Escherichia coli E24377A guanosine 5'-monophosphate oxidoreductase YP_001461274.1 115018 D 331111 CDS YP_001461275.1 157158124 5589870 complement(117288..118673) 1 NC_009801.1 identified by match to protein family HMM PF00437; hypothetical protein 118673 hofB 5589870 hofB Escherichia coli E24377A hypothetical protein YP_001461275.1 117288 R 331111 CDS YP_001461276.1 157156035 5590855 complement(118683..119123) 1 NC_009801.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; major pilin subunit 119123 pilA 5590855 pilA Escherichia coli E24377A major pilin subunit YP_001461276.1 118683 R 331111 CDS YP_001461277.1 157156557 5585964 complement(119326..120219) 1 NC_009801.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 120219 nadC 5585964 nadC Escherichia coli E24377A quinolinate phosphoribosyltransferase YP_001461277.1 119326 R 331111 CDS YP_001461278.1 157157834 5586289 120307..120858 1 NC_009801.1 identified by similarity to SP:P13016; match to protein family HMM PF01510; N-acetyl-anhydromuranmyl-L-alanine amidase 120858 ampD 5586289 ampD Escherichia coli E24377A N-acetyl-anhydromuranmyl-L-alanine amidase YP_001461278.1 120307 D 331111 CDS YP_001461279.1 157157473 5589093 120855..121709 1 NC_009801.1 involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 121709 ampE 5589093 ampE Escherichia coli E24377A regulatory protein AmpE YP_001461279.1 120855 D 331111 CDS YP_001461280.1 157156546 5586474 complement(121752..123122) 1 NC_009801.1 identified by similarity to SP:P15993; match to protein family HMM PF00324; aromatic amino acid transporter 123122 aroP 5586474 aroP Escherichia coli E24377A aromatic amino acid transporter YP_001461280.1 121752 R 331111 CDS YP_001461281.1 157156176 5590200 123666..124430 1 NC_009801.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 124430 pdhR 5590200 pdhR Escherichia coli E24377A transcriptional regulator PdhR YP_001461281.1 123666 D 331111 CDS YP_001461282.1 157155188 5589741 124591..127254 1 NC_009801.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 127254 aceE 5589741 aceE Escherichia coli E24377A pyruvate dehydrogenase subunit E1 YP_001461282.1 124591 D 331111 CDS YP_001461283.1 157154816 5590099 127269..129161 1 NC_009801.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 129161 aceF 5590099 aceF Escherichia coli E24377A dihydrolipoamide acetyltransferase YP_001461283.1 127269 D 331111 CDS YP_001461284.1 157158655 5587205 129486..130910 1 NC_009801.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 130910 lpdA 5587205 lpdA Escherichia coli E24377A dihydrolipoamide dehydrogenase YP_001461284.1 129486 D 331111 CDS YP_001461285.1 157156701 5589180 complement(130981..132834) 1 NC_009801.1 identified by similarity to GB:BAB33544.1; hypothetical protein 132834 5589180 EcE24377A_0119 Escherichia coli E24377A hypothetical protein YP_001461285.1 130981 R 331111 CDS YP_001461286.1 157154794 5590861 133189..135786 1 NC_009801.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 135786 acnB 5590861 acnB Escherichia coli E24377A bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_001461286.1 133189 D 331111 CDS YP_001461287.1 157155236 5588282 135961..136323 1 NC_009801.1 identified by similarity to SP:P59396; match to protein family HMM PF06062; hypothetical protein 136323 5588282 EcE24377A_0121 Escherichia coli E24377A hypothetical protein YP_001461287.1 135961 D 331111 CDS YP_001461288.1 157158809 5589812 complement(136361..137155) 1 NC_009801.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 137155 speD 5589812 speD Escherichia coli E24377A S-adenosylmethionine decarboxylase YP_001461288.1 136361 R 331111 CDS YP_001461289.1 157159323 5588895 complement(137171..138037) 1 NC_009801.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 138037 speE 5588895 speE Escherichia coli E24377A spermidine synthase YP_001461289.1 137171 R 331111 CDS YP_001461290.1 157157466 5586246 complement(138143..138490) 1 NC_009801.1 hypothetical protein 138490 5586246 EcE24377A_0124 Escherichia coli E24377A hypothetical protein YP_001461290.1 138143 R 331111 CDS YP_001461291.1 157157987 5588097 138617..140206 1 NC_009801.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 140206 cueO 5588097 cueO Escherichia coli E24377A multicopper oxidase YP_001461291.1 138617 D 331111 CDS YP_001461292.1 157155401 5587261 complement(140253..142643) 1 NC_009801.1 identified by similarity to SP:P15877; match to protein family HMM PF01011; match to protein family HMM TIGR03074; glucose dehydrogenase 142643 gcd 5587261 gcd Escherichia coli E24377A glucose dehydrogenase YP_001461292.1 140253 R 331111 CDS YP_001461293.1 157155923 5587457 142849..143385 1 NC_009801.1 identified by similarity to SP:P0A9M2; match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine phosphoribosyltransferase 143385 hpt 5587457 hpt Escherichia coli E24377A hypoxanthine phosphoribosyltransferase YP_001461293.1 142849 D 331111 CDS YP_001461294.1 157158806 5589571 complement(143426..144088) 1 NC_009801.1 catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase 144088 can 5589571 can Escherichia coli E24377A carbonic anhydrase YP_001461294.1 143426 R 331111 CDS YP_001461295.1 157154875 5589095 144197..145123 1 NC_009801.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 145123 5589095 EcE24377A_0129 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001461295.1 144197 D 331111 CDS YP_001461296.1 157157883 5587405 145120..145890 1 NC_009801.1 identified by match to protein family HMM PF01061; ABC transporter permease 145890 5587405 EcE24377A_0130 Escherichia coli E24377A ABC transporter permease YP_001461296.1 145120 D 331111 CDS YP_001461297.1 157159200 5588225 145995..146435 1 NC_009801.1 identified by match to protein family HMM PF03610; PTS system transporter subunit IIA 146435 5588225 EcE24377A_0131 Escherichia coli E24377A PTS system transporter subunit IIA YP_001461297.1 145995 D 331111 CDS YP_001461298.1 157156843 5589341 146499..147728 1 NC_009801.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase 147728 5589341 EcE24377A_0132 Escherichia coli E24377A polysaccharide deacetylase YP_001461298.1 146499 D 331111 CDS YP_001461299.1 157157631 5589361 complement(147732..148112) 1 NC_009801.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 148112 panD 5589361 panD Escherichia coli E24377A aspartate alpha-decarboxylase YP_001461299.1 147732 R 331111 CDS YP_001461300.1 157155804 5589774 148080..148274 1 NC_009801.1 identified by glimmer; hypothetical protein 148274 5589774 EcE24377A_0134 Escherichia coli E24377A hypothetical protein YP_001461300.1 148080 D 331111 CDS YP_001461301.1 157156067 5588682 148386..149288 1 NC_009801.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein 149288 5588682 EcE24377A_0135 Escherichia coli E24377A hypothetical protein YP_001461301.1 148386 D 331111 CDS YP_001461302.1 157158388 5590089 complement(149362..150213) 1 NC_009801.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 150213 panC 5590089 panC Escherichia coli E24377A pantoate--beta-alanine ligase YP_001461302.1 149362 R 331111 CDS YP_001461303.1 157158907 5590338 complement(150225..151019) 1 NC_009801.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 151019 panB 5590338 panB Escherichia coli E24377A 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_001461303.1 150225 R 331111 CDS YP_001461304.1 157158069 5587036 complement(151132..152406) 1 NC_009801.1 identified by match to protein family HMM PF00419; fimbrial-like adhesin protein 152406 5587036 EcE24377A_0138 Escherichia coli E24377A fimbrial-like adhesin protein YP_001461304.1 151132 R 331111 CDS YP_001461305.1 157156785 5590847 complement(152459..153055) 1 NC_009801.1 identified by similarity to GB:AAZ86939.1; hypothetical protein 153055 5590847 EcE24377A_0139 Escherichia coli E24377A hypothetical protein YP_001461305.1 152459 R 331111 CDS YP_001461306.1 157154780 5588655 complement(153082..153684) 1 NC_009801.1 identified by match to protein family HMM PF00419; fimbrial protein 153684 5588655 EcE24377A_0140 Escherichia coli E24377A fimbrial protein YP_001461306.1 153082 R 331111 CDS YP_001461307.1 157155430 5590145 complement(153686..153781) 1 NC_009801.1 identified by glimmer; hypothetical protein 153781 5590145 EcE24377A_0141 Escherichia coli E24377A hypothetical protein YP_001461307.1 153686 R 331111 CDS YP_001461308.1 157155946 5590283 complement(154285..156885) 1 NC_009801.1 similar to the fimbrial usher protein PapC; outer membrane usher protein 156885 5590283 EcE24377A_0142 Escherichia coli E24377A outer membrane usher protein YP_001461308.1 154285 R 331111 CDS YP_001461309.1 157156746 5587862 complement(156920..157660) 1 NC_009801.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; chaperone protein EcpD 157660 5587862 EcE24377A_0143 Escherichia coli E24377A chaperone protein EcpD YP_001461309.1 156920 R 331111 CDS YP_001461310.1 157155183 5589158 157640..157753 1 NC_009801.1 identified by glimmer; hypothetical protein 157753 5589158 EcE24377A_0144 Escherichia coli E24377A hypothetical protein YP_001461310.1 157640 D 331111 CDS YP_001461311.1 157155344 5589649 complement(157765..158349) 1 NC_009801.1 identified by similarity to SP:P08190; match to protein family HMM PF00419; fimbrial protein 158349 5589649 EcE24377A_0145 Escherichia coli E24377A fimbrial protein YP_001461311.1 157765 R 331111 CDS YP_001461312.1 157158607 5590014 complement(158719..159198) 1 NC_009801.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 159198 folK 5590014 folK Escherichia coli E24377A 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_001461312.1 158719 R 331111 CDS YP_001461313.1 157159375 5586901 complement(159195..160559) 1 NC_009801.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase 160559 pcnB 5586901 pcnB Escherichia coli E24377A poly(A) polymerase YP_001461313.1 159195 R 331111 CDS YP_001461314.1 157159053 5588887 complement(160652..161578) 1 NC_009801.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 161578 gluQ 5588887 gluQ Escherichia coli E24377A glutamyl-Q tRNA(Asp) synthetase YP_001461314.1 160652 R 331111 CDS YP_001461315.1 157158209 5588850 complement(161615..162070) 1 NC_009801.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02420; RNA polymerase-binding transcription factor 162070 dksA 5588850 dksA Escherichia coli E24377A RNA polymerase-binding transcription factor YP_001461315.1 161615 R 331111 CDS YP_001461316.1 157156627 5588404 complement(162248..162952) 1 NC_009801.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 162952 sfsA 5588404 sfsA Escherichia coli E24377A sugar fermentation stimulation protein A YP_001461316.1 162248 R 331111 CDS YP_001461317.1 157154764 5587101 complement(162967..163497) 1 NC_009801.1 identified by match to protein family HMM PF02834; match to protein family HMM TIGR02258; 2'-5' RNA ligase 163497 ligT 5587101 ligT Escherichia coli E24377A 2'-5' RNA ligase YP_001461317.1 162967 R 331111 CDS YP_001461318.1 157156250 5588840 163571..166000 1 NC_009801.1 similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 166000 hrpB 5588840 hrpB Escherichia coli E24377A ATP-dependent RNA helicase HrpB YP_001461318.1 163571 D 331111 CDS YP_001461319.1 157158219 5586941 166196..168730 1 NC_009801.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 168730 mrcB 5586941 mrcB Escherichia coli E24377A penicillin-binding protein 1b YP_001461319.1 166196 D 331111 CDS YP_001461320.1 157157969 5587133 complement(168795..168929) 1 NC_009801.1 identified by glimmer; hypothetical protein 168929 5587133 EcE24377A_0154 Escherichia coli E24377A hypothetical protein YP_001461320.1 168795 R 331111 CDS YP_001461321.1 157157325 5590762 168950..171193 1 NC_009801.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 171193 fhuA 5590762 fhuA Escherichia coli E24377A ferrichrome outer membrane transporter YP_001461321.1 168950 D 331111 CDS YP_001461322.1 157158286 5585968 171244..172041 1 NC_009801.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 172041 fhuC 5585968 fhuC Escherichia coli E24377A iron-hydroxamate transporter ATP-binding subunit YP_001461322.1 171244 D 331111 CDS YP_001461323.1 157155549 5587176 172041..172931 1 NC_009801.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 172931 fhuD 5587176 fhuD Escherichia coli E24377A iron-hydroxamate transporter substrate-binding subunit YP_001461323.1 172041 D 331111 CDS YP_001461324.1 157155293 5590271 172928..174910 1 NC_009801.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 174910 fhuB 5590271 fhuB Escherichia coli E24377A iron-hydroxamate transporter permease subunit YP_001461324.1 172928 D 331111 CDS YP_001461325.1 157155177 5589671 complement(174945..176225) 1 NC_009801.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 176225 hemL 5589671 hemL Escherichia coli E24377A glutamate-1-semialdehyde aminotransferase YP_001461325.1 174945 R 331111 CDS YP_001461326.1 157156910 5588754 176450..177871 1 NC_009801.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 177871 clcA 5588754 clcA Escherichia coli E24377A chloride channel protein YP_001461326.1 176450 D 331111 CDS YP_001461327.1 157156275 5588551 177953..178297 1 NC_009801.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 178297 5588551 EcE24377A_0161 Escherichia coli E24377A iron-sulfur cluster insertion protein ErpA YP_001461327.1 177953 D 331111 CDS YP_001461328.1 157157954 5589334 complement(178344..178967) 1 NC_009801.1 identified by match to protein family HMM PF03458; hypothetical protein 178967 5589334 EcE24377A_0162 Escherichia coli E24377A hypothetical protein YP_001461328.1 178344 R 331111 CDS YP_001461329.1 157157282 5589415 complement(179005..179805) 1 NC_009801.1 solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF 179805 btuF 5589415 btuF Escherichia coli E24377A vitamin B12-transporter protein BtuF YP_001461329.1 179005 R 331111 CDS YP_001461330.1 157158960 5590428 complement(179798..180496) 1 NC_009801.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 180496 mtnN 5590428 mtnN Escherichia coli E24377A 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_001461330.1 179798 R 331111 CDS YP_001461331.1 157155851 5585949 180580..182097 1 NC_009801.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 182097 dgt 5585949 dgt Escherichia coli E24377A deoxyguanosinetriphosphate triphosphohydrolase YP_001461331.1 180580 D 331111 CDS YP_001461332.1 157155195 5587049 182227..183651 1 NC_009801.1 protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 183651 degP 5587049 degP Escherichia coli E24377A serine endoprotease YP_001461332.1 182227 D 331111 CDS YP_001461333.1 157156858 5587960 183833..184963 1 NC_009801.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 184963 cdaR 5587960 cdaR Escherichia coli E24377A carbohydrate diacid transcriptional activator CdaR YP_001461333.1 183833 D 331111 CDS YP_001461334.1 157156211 5589200 complement(185052..185438) 1 NC_009801.1 hypothetical protein 185438 5589200 EcE24377A_0168 Escherichia coli E24377A hypothetical protein YP_001461334.1 185052 R 331111 CDS YP_001461335.1 157156037 5587337 complement(185753..186577) 1 NC_009801.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 186577 dapD 5587337 dapD Escherichia coli E24377A 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_001461335.1 185753 R 331111 CDS YP_001461336.1 157157798 5589363 complement(186608..189280) 1 NC_009801.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 189280 glnD 5589363 glnD Escherichia coli E24377A PII uridylyl-transferase YP_001461336.1 186608 R 331111 CDS YP_001461337.1 157157350 5589009 complement(189342..190136) 1 NC_009801.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 190136 map 5589009 map Escherichia coli E24377A methionine aminopeptidase YP_001461337.1 189342 R 331111 CDS YP_001461338.1 157159281 5589364 190504..191229 1 NC_009801.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 191229 rpsB 5589364 rpsB Escherichia coli E24377A 30S ribosomal protein S2 YP_001461338.1 190504 D 331111 CDS YP_001461339.1 157158600 5588226 191487..192338 1 NC_009801.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 192338 tsf 5588226 tsf Escherichia coli E24377A elongation factor Ts YP_001461339.1 191487 D 331111 CDS YP_001461340.1 157155844 5586966 192485..193210 1 NC_009801.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 193210 pyrH 5586966 pyrH Escherichia coli E24377A uridylate kinase YP_001461340.1 192485 D 331111 CDS YP_001461341.1 157155211 5587023 193502..194059 1 NC_009801.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 194059 frr 5587023 frr Escherichia coli E24377A ribosome recycling factor YP_001461341.1 193502 D 331111 CDS YP_001461342.1 157156618 5587148 194151..195347 1 NC_009801.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 195347 dxr 5587148 dxr Escherichia coli E24377A 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_001461342.1 194151 D 331111 CDS YP_001461343.1 157155987 5587225 195536..196294 1 NC_009801.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 196294 uppS 5587225 uppS Escherichia coli E24377A undecaprenyl pyrophosphate synthase YP_001461343.1 195536 D 331111 CDS YP_001461344.1 157158930 5585973 196307..197164 1 NC_009801.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 197164 cdsA 5585973 cdsA Escherichia coli E24377A CDP-diglyceride synthase YP_001461344.1 196307 D 331111 CDS YP_001461345.1 157156244 5588518 197176..198528 1 NC_009801.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 198528 rseP 5588518 rseP Escherichia coli E24377A zinc metallopeptidase RseP YP_001461345.1 197176 D 331111 CDS YP_001461346.1 157155563 5586085 198558..200990 1 NC_009801.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 200990 yaeT 5586085 yaeT Escherichia coli E24377A outer membrane protein assembly factor YaeT YP_001461346.1 198558 D 331111 CDS YP_001461347.1 157155451 5589902 201112..201597 1 NC_009801.1 identified by similarity to SP:P31519; match to protein family HMM PF03938; periplasmic chaperone 201597 skp 5589902 skp Escherichia coli E24377A periplasmic chaperone YP_001461347.1 201112 D 331111 CDS YP_001461348.1 157154842 5586675 201601..202626 1 NC_009801.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 202626 lpxD 5586675 lpxD Escherichia coli E24377A UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_001461348.1 201601 D 331111 CDS YP_001461349.1 157156776 5590406 202731..203186 1 NC_009801.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 203186 fabZ 5590406 fabZ Escherichia coli E24377A (3R)-hydroxymyristoyl-ACP dehydratase YP_001461349.1 202731 D 331111 CDS YP_001461350.1 157156102 5589140 203190..203978 1 NC_009801.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 203978 lpxA 5589140 lpxA Escherichia coli E24377A UDP-N-acetylglucosamine acyltransferase YP_001461350.1 203190 D 331111 CDS YP_001461351.1 157158059 5590380 203978..205126 1 NC_009801.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 205126 lpxB 5590380 lpxB Escherichia coli E24377A lipid-A-disaccharide synthase YP_001461351.1 203978 D 331111 CDS YP_001461352.1 157157454 5587001 205123..205719 1 NC_009801.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 205719 rnhB 5587001 rnhB Escherichia coli E24377A ribonuclease HII YP_001461352.1 205123 D 331111 CDS YP_001461353.1 157158983 5586391 205756..209238 1 NC_009801.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 209238 dnaE 5586391 dnaE Escherichia coli E24377A DNA polymerase III subunit alpha YP_001461353.1 205756 D 331111 CDS YP_001461354.1 157155750 5590409 209251..210210 1 NC_009801.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 210210 accA 5590409 accA Escherichia coli E24377A acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_001461354.1 209251 D 331111 CDS YP_001461355.1 157155550 5589236 210309..212450 1 NC_009801.1 identified by similarity to SP:P52095; match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; lysine decarboxylase, constitutive 212450 ldcC 5589236 ldcC Escherichia coli E24377A lysine decarboxylase, constitutive YP_001461355.1 210309 D 331111 CDS YP_001461356.1 157155586 5586260 212507..212896 1 NC_009801.1 identified by match to protein family HMM PF00903; hypothetical protein 212896 5586260 EcE24377A_0191 Escherichia coli E24377A hypothetical protein YP_001461356.1 212507 D 331111 CDS YP_001461357.1 157158325 5589780 212961..214259 1 NC_009801.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 214259 tilS 5589780 tilS Escherichia coli E24377A tRNA(Ile)-lysidine synthetase YP_001461357.1 212961 D 331111 CDS YP_001461358.1 157155017 5587746 complement(214308..214568) 1 NC_009801.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator 214568 rof 5587746 rof Escherichia coli E24377A Rho-binding antiterminator YP_001461358.1 214308 R 331111 CDS YP_001461359.1 157154914 5586428 complement(214555..214755) 1 NC_009801.1 identified by match to protein family HMM PF06786; hypothetical protein 214755 5586428 EcE24377A_0194 Escherichia coli E24377A hypothetical protein YP_001461359.1 214555 R 331111 CDS YP_001461360.1 157156424 5587220 214921..215466 1 NC_009801.1 identified by match to protein family HMM PF07152; hypothetical protein 215466 5587220 EcE24377A_0195 Escherichia coli E24377A hypothetical protein YP_001461360.1 214921 D 331111 CDS YP_001461361.1 157157087 5588021 215463..215885 1 NC_009801.1 identified by match to protein family HMM PF00472; peptidyl-tRNA hydrolase domain-containing protein 215885 5588021 EcE24377A_0196 Escherichia coli E24377A peptidyl-tRNA hydrolase domain-containing protein YP_001461361.1 215463 D 331111 CDS YP_001461362.1 157157173 5590582 215899..216609 1 NC_009801.1 identified by match to protein family HMM PF04170; lipoprotein involved with copper homeostasis and adhesion 216609 cutF 5590582 cutF Escherichia coli E24377A lipoprotein involved with copper homeostasis and adhesion YP_001461362.1 215899 D 331111 CDS YP_001461363.1 157157308 5588167 216859..217839 1 NC_009801.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 217839 5588167 EcE24377A_0198 Escherichia coli E24377A IS621, transposase YP_001461363.1 216859 D 331111 CDS YP_001461364.1 157156272 5586009 217966..218076 1 NC_009801.1 identified by glimmer; hypothetical protein 218076 5586009 EcE24377A_0200 Escherichia coli E24377A hypothetical protein YP_001461364.1 217966 D 331111 CDS YP_001461365.1 157156008 5587814 complement(218919..220637) 1 NC_009801.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 220637 proS 5587814 proS Escherichia coli E24377A prolyl-tRNA synthetase YP_001461365.1 218919 R 331111 CDS YP_001461366.1 157155318 5586773 complement(220749..221456) 1 NC_009801.1 identified by match to protein family HMM PF01980; match to protein family HMM TIGR00104; hypothetical protein 221456 5586773 EcE24377A_0202 Escherichia coli E24377A hypothetical protein YP_001461366.1 220749 R 331111 CDS YP_001461367.1 157154956 5588215 complement(221453..221857) 1 NC_009801.1 outer membrane lipoprotein 221857 rcsF 5588215 rcsF Escherichia coli E24377A outer membrane lipoprotein YP_001461367.1 221453 R 331111 CDS YP_001461368.1 157159295 5587140 complement(221975..222790) 1 NC_009801.1 identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363; DL-methionine transporter substrate-binding subunit 222790 metQ 5587140 metQ Escherichia coli E24377A DL-methionine transporter substrate-binding subunit YP_001461368.1 221975 R 331111 CDS YP_001461369.1 157158636 5587597 complement(222830..223483) 1 NC_009801.1 part of the MetNIQ methionine uptake system; DL-methionine transporter permease 223483 metI 5587597 metI Escherichia coli E24377A DL-methionine transporter permease YP_001461369.1 222830 R 331111 CDS YP_001461370.1 157158405 5588083 complement(223476..224507) 1 NC_009801.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 224507 metN 5588083 metN Escherichia coli E24377A DL-methionine transporter ATP-binding subunit YP_001461370.1 223476 R 331111 CDS YP_001461371.1 157157978 5590359 224695..225270 1 NC_009801.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 225270 5590359 EcE24377A_0207 Escherichia coli E24377A D,D-heptose 1,7-bisphosphate phosphatase YP_001461371.1 224695 D 331111 CDS YP_001461372.1 157159277 5589583 231166..231969 1 NC_009801.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 231969 dkgB 5589583 dkgB Escherichia coli E24377A 2,5-diketo-D-gluconate reductase B YP_001461372.1 231166 D 331111 CDS YP_001461373.1 157155058 5588132 complement(231966..232880) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 232880 5588132 EcE24377A_0212 Escherichia coli E24377A LysR family transcriptional regulator YP_001461373.1 231966 R 331111 CDS YP_001461374.1 157155840 5586303 233121..233921 1 NC_009801.1 identified by match to protein family HMM PF03372; hypothetical protein 233921 5586303 EcE24377A_0214 Escherichia coli E24377A hypothetical protein YP_001461374.1 233121 D 331111 CDS YP_001461375.1 157156387 5589512 233999..234769 1 NC_009801.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242; UbiE/COQ5 family methlytransferase 234769 5589512 EcE24377A_0215 Escherichia coli E24377A UbiE/COQ5 family methlytransferase YP_001461375.1 233999 D 331111 CDS YP_001461376.1 157157200 5589079 complement(234817..236175) 1 NC_009801.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D 236175 mltD 5589079 mltD Escherichia coli E24377A membrane-bound lytic murein transglycosylase D YP_001461376.1 234817 R 331111 CDS YP_001461377.1 157157699 5587003 complement(236247..237002) 1 NC_009801.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase 237002 gloB 5587003 gloB Escherichia coli E24377A hydroxyacylglutathione hydrolase YP_001461377.1 236247 R 331111 CDS YP_001461378.1 157155536 5586635 237036..237758 1 NC_009801.1 identified by match to protein family HMM PF08241; methyltransferase 237758 5586635 EcE24377A_0220 Escherichia coli E24377A methyltransferase YP_001461378.1 237036 D 331111 CDS YP_001461379.1 157157206 5589198 complement(237199..237327) 1 NC_009801.1 identified by glimmer; hypothetical protein 237327 5589198 EcE24377A_0218 Escherichia coli E24377A hypothetical protein YP_001461379.1 237199 R 331111 CDS YP_001461380.1 157156093 5590327 complement(237755..238222) 1 NC_009801.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 238222 rnhA 5590327 rnhA Escherichia coli E24377A ribonuclease H YP_001461380.1 237755 R 331111 CDS YP_001461381.1 157156660 5586594 238287..239018 1 NC_009801.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 239018 dnaQ 5586594 dnaQ Escherichia coli E24377A DNA polymerase III subunit epsilon YP_001461381.1 238287 D 331111 CDS YP_001461382.1 157157811 5588354 239237..239335 1 NC_009801.1 identified by glimmer; hypothetical protein 239335 5588354 EcE24377A_0223 Escherichia coli E24377A hypothetical protein YP_001461382.1 239237 D 331111 CDS YP_001461383.1 157158497 5587700 239557..240342 1 NC_009801.1 lipoprotein 240342 5587700 EcE24377A_0224 Escherichia coli E24377A lipoprotein YP_001461383.1 239557 D 331111 CDS YP_001461384.1 157159163 5588668 complement(240968..241882) 1 NC_009801.1 hypothetical protein 241882 5588668 EcE24377A_0225 Escherichia coli E24377A hypothetical protein YP_001461384.1 240968 R 331111 CDS YP_001461385.1 157155635 5590609 complement(241926..242408) 1 NC_009801.1 identified by similarity to GB:CAE12300.1; match to protein family HMM PF05638; match to protein family HMM TIGR03344; hypothetical protein 242408 5590609 EcE24377A_0226 Escherichia coli E24377A hypothetical protein YP_001461385.1 241926 R 331111 CDS YP_001461386.1 157155016 5589762 complement(242432..243784) 1 NC_009801.1 identified by match to protein family HMM PF06812; ImpA domain-containing protein 243784 5589762 EcE24377A_0227 Escherichia coli E24377A ImpA domain-containing protein YP_001461386.1 242432 R 331111 CDS YP_001461387.1 157155738 5588746 complement(243795..247319) 1 NC_009801.1 identified by match to protein family HMM PF06744; match to protein family HMM PF06761; match to protein family HMM TIGR03348; hypothetical protein 247319 5588746 EcE24377A_0228 Escherichia coli E24377A hypothetical protein YP_001461387.1 243795 R 331111 CDS YP_001461388.1 157156439 5589705 complement(247338..248750) 1 NC_009801.1 identified by match to protein family HMM PF06812; match to protein family HMM TIGR03362; ImpA domain-containing protein 248750 5589705 EcE24377A_0229 Escherichia coli E24377A ImpA domain-containing protein YP_001461388.1 247338 R 331111 CDS YP_001461389.1 157157081 5586718 complement(248755..249498) 1 NC_009801.1 identified by match to protein family HMM TIGR03360; type VI secretion-associated protein 249498 5586718 EcE24377A_0230 Escherichia coli E24377A type VI secretion-associated protein YP_001461389.1 248755 R 331111 CDS YP_001461390.1 157157697 5589718 complement(249495..252254) 1 NC_009801.1 identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03345; ATP-dependent chaperone protein ClpB 252254 5589718 EcE24377A_0231 Escherichia coli E24377A ATP-dependent chaperone protein ClpB YP_001461390.1 249495 R 331111 CDS YP_001461391.1 157158272 5586638 complement(252263..253024) 1 NC_009801.1 identified by similarity to GB:AAF96029.1; match to protein family HMM TIGR03349; hypothetical protein 253024 5586638 EcE24377A_0232 Escherichia coli E24377A hypothetical protein YP_001461391.1 252263 R 331111 CDS YP_001461392.1 157159130 5588035 complement(253029..254360) 1 NC_009801.1 identified by similarity to GB:AAM83869.1; match to protein family HMM PF05936; match to protein family HMM TIGR03353; hypothetical protein 254360 5588035 EcE24377A_0233 Escherichia coli E24377A hypothetical protein YP_001461392.1 253029 R 331111 CDS YP_001461393.1 157158389 5587635 complement(254363..254887) 1 NC_009801.1 identified by match to protein family HMM TIGR03352; type VI secretion lipoprotein 254887 5587635 EcE24377A_0234 Escherichia coli E24377A type VI secretion lipoprotein YP_001461393.1 254363 R 331111 CDS YP_001461394.1 157159137 5590339 complement(254884..256164) 1 NC_009801.1 identified by similarity to GB:CAC92824.1; match to protein family HMM TIGR03354; hypothetical protein 256164 5590339 EcE24377A_0235 Escherichia coli E24377A hypothetical protein YP_001461394.1 254884 R 331111 CDS YP_001461395.1 157158454 5588261 complement(256189..257271) 1 NC_009801.1 identified by similarity to GB:BAB33651.1; match to protein family HMM PF06996; match to protein family HMM TIGR03347; hypothetical protein 257271 5588261 EcE24377A_0236 Escherichia coli E24377A hypothetical protein YP_001461395.1 256189 R 331111 CDS YP_001461396.1 157155723 5587361 complement(257235..259085) 1 NC_009801.1 identified by similarity to GB:AAZ87034.1; match to protein family HMM PF05947; match to protein family HMM TIGR03359; hypothetical protein 259085 5587361 EcE24377A_0237 Escherichia coli E24377A hypothetical protein YP_001461396.1 257235 R 331111 CDS YP_001461397.1 157155067 5587623 complement(259089..259502) 1 NC_009801.1 identified by similarity to GB:CAG76342.1; match to protein family HMM PF04965; match to protein family HMM TIGR03357; hypothetical protein 259502 5587623 EcE24377A_0238 Escherichia coli E24377A hypothetical protein YP_001461397.1 259089 R 331111 CDS YP_001461398.1 157157099 5587080 complement(259509..260984) 1 NC_009801.1 identified by similarity to GB:BAB33654.1; match to protein family HMM PF05943; match to protein family HMM TIGR03355; hypothetical protein 260984 5587080 EcE24377A_0239 Escherichia coli E24377A hypothetical protein YP_001461398.1 259509 R 331111 CDS YP_001461399.1 157156295 5587554 complement(261035..261259) 1 NC_009801.1 identified by glimmer; hypothetical protein 261259 5587554 EcE24377A_0240 Escherichia coli E24377A hypothetical protein YP_001461399.1 261035 R 331111 CDS YP_001461400.1 157158244 5589240 complement(261294..261794) 1 NC_009801.1 identified by similarity to GB:AAZ87038.1; match to protein family HMM PF05591; match to protein family HMM TIGR03358; hypothetical protein 261794 5589240 EcE24377A_0241 Escherichia coli E24377A hypothetical protein YP_001461400.1 261294 R 331111 CDS YP_001461401.1 157157420 5590172 262222..262365 1 NC_009801.1 identified by glimmer; hypothetical protein 262365 5590172 EcE24377A_0242 Escherichia coli E24377A hypothetical protein YP_001461401.1 262222 D 331111 CDS YP_001461402.1 157157744 5588608 262492..263010 1 NC_009801.1 identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344; hypothetical protein 263010 5588608 EcE24377A_0243 Escherichia coli E24377A hypothetical protein YP_001461402.1 262492 D 331111 CDS YP_001461403.1 157157261 5589419 263043..263180 1 NC_009801.1 identified by glimmer; hypothetical protein 263180 5589419 EcE24377A_0244 Escherichia coli E24377A hypothetical protein YP_001461403.1 263043 D 331111 CDS YP_001461404.1 157159093 5589586 263220..265361 1 NC_009801.1 identified by match to protein family HMM PF04524; match to protein family HMM PF06715; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361; ImpA family type VI secretion-associated protein 265361 5589586 EcE24377A_0245 Escherichia coli E24377A ImpA family type VI secretion-associated protein YP_001461404.1 263220 D 331111 CDS YP_001461405.1 157158534 5587711 265437..269684 1 NC_009801.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; Rhs protein 269684 5587711 EcE24377A_0246 Escherichia coli E24377A Rhs protein YP_001461405.1 265437 D 331111 CDS YP_001461406.1 157155100 5587417 269668..270150 1 NC_009801.1 hypothetical protein 270150 5587417 EcE24377A_0247 Escherichia coli E24377A hypothetical protein YP_001461406.1 269668 D 331111 CDS YP_001461407.1 157158346 5589895 complement(272738..273508) 1 NC_009801.1 identified by match to protein family HMM PF00795; hypothetical protein 273508 5589895 EcE24377A_0251 Escherichia coli E24377A hypothetical protein YP_001461407.1 272738 R 331111 CDS YP_001461408.1 157158901 5589606 273662..274135 1 NC_009801.1 inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 274135 5589606 EcE24377A_0252 Escherichia coli E24377A C-lysozyme inhibitor YP_001461408.1 273662 D 331111 CDS YP_001461409.1 157159278 5586404 complement(274178..276622) 1 NC_009801.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 276622 fadE 5586404 fadE Escherichia coli E24377A acyl-CoA dehydrogenase YP_001461409.1 274178 R 331111 CDS YP_001461410.1 157157983 5587536 276862..277440 1 NC_009801.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 277440 gmhA 5587536 gmhA Escherichia coli E24377A phosphoheptose isomerase YP_001461410.1 276862 D 331111 CDS YP_001461411.1 157156263 5588194 277494..277586 1 NC_009801.1 identified by glimmer; hypothetical protein 277586 5588194 EcE24377A_0255 Escherichia coli E24377A hypothetical protein YP_001461411.1 277494 D 331111 CDS YP_001461412.1 157155204 5588578 277646..278413 1 NC_009801.1 identified by match to protein family HMM PF00310; glutamine amidotransferase 278413 5588578 EcE24377A_0257 Escherichia coli E24377A glutamine amidotransferase YP_001461412.1 277646 D 331111 CDS YP_001461413.1 157156909 5587647 complement(278384..279124) 1 NC_009801.1 identified by match to protein family HMM PF06104; hypothetical protein 279124 5587647 EcE24377A_0256 Escherichia coli E24377A hypothetical protein YP_001461413.1 278384 R 331111 CDS YP_001461414.1 157155410 5587896 complement(279280..279558) 1 NC_009801.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR00053; match to protein family HMM TIGR02385; hypothetical protein 279558 5587896 EcE24377A_0258 Escherichia coli E24377A hypothetical protein YP_001461414.1 279280 R 331111 CDS YP_001461415.1 157155542 5589799 complement(279561..279821) 1 NC_009801.1 identified by similarity to SP:Q47150; match to protein family HMM PF04221; match to protein family HMM TIGR02384; addiction module antitoxin 279821 5589799 EcE24377A_0259 Escherichia coli E24377A addiction module antitoxin YP_001461415.1 279561 R 331111 CDS YP_001461416.1 157158742 5589466 279971..280780 1 NC_009801.1 identified by match to protein family HMM PF00877; NlpC/P60 family protein 280780 5589466 EcE24377A_0261 Escherichia coli E24377A NlpC/P60 family protein YP_001461416.1 279971 D 331111 CDS YP_001461417.1 157156570 5588459 complement(280015..280128) 1 NC_009801.1 identified by glimmer; hypothetical protein 280128 5588459 EcE24377A_0260 Escherichia coli E24377A hypothetical protein YP_001461417.1 280015 R 331111 CDS YP_001461418.1 157155695 5588041 complement(280837..281193) 1 NC_009801.1 identified by match to protein family HMM PF05534; HicB family protein 281193 5588041 EcE24377A_0262 Escherichia coli E24377A HicB family protein YP_001461418.1 280837 R 331111 CDS YP_001461419.1 157158104 5590491 complement(281569..283308) 1 NC_009801.1 identified by match to protein family HMM PF00771; protein FhiA 283308 fhiA 5590491 fhiA Escherichia coli E24377A protein FhiA YP_001461419.1 281569 R 331111 CDS YP_001461420.1 157157459 5588947 283268..284038 1 NC_009801.1 identified by match to protein family HMM PF00691; hypothetical protein 284038 5588947 EcE24377A_0264 Escherichia coli E24377A hypothetical protein YP_001461420.1 283268 D 331111 CDS YP_001461421.1 157156229 5588122 284109..285164 1 NC_009801.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 285164 dinB 5588122 dinB Escherichia coli E24377A DNA polymerase IV YP_001461421.1 284109 D 331111 CDS YP_001461422.1 157157833 5586883 285161..285613 1 NC_009801.1 identified by match to protein family HMM PF00583; hypothetical protein 285613 5586883 EcE24377A_0266 Escherichia coli E24377A hypothetical protein YP_001461422.1 285161 D 331111 CDS YP_001461423.1 157156603 5588434 285832..286998 1 NC_009801.1 mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; hypothetical protein 286998 5588434 EcE24377A_0267 Escherichia coli E24377A hypothetical protein YP_001461423.1 285832 D 331111 CDS YP_001461424.1 157156041 5589004 286995..287609 1 NC_009801.1 similar to release factor 1 and 2; peptide chain release factor-like protein 287609 prfH 5589004 prfH Escherichia coli E24377A peptide chain release factor-like protein YP_001461424.1 286995 D 331111 CDS YP_001461425.1 157155499 5590667 complement(287666..289123) 1 NC_009801.1 identified by similarity to SP:P15288; match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893; aminoacyl-histidine dipeptidase 289123 pepD 5590667 pepD Escherichia coli E24377A aminoacyl-histidine dipeptidase YP_001461425.1 287666 R 331111 CDS YP_001461426.1 157155543 5590037 289384..289842 1 NC_009801.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 289842 gpt 5590037 gpt Escherichia coli E24377A xanthine-guanine phosphoribosyltransferase YP_001461426.1 289384 D 331111 CDS YP_001461427.1 157159176 5589467 289934..291178 1 NC_009801.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 291178 frsA 5589467 frsA Escherichia coli E24377A fermentation/respiration switch protein YP_001461427.1 289934 D 331111 CDS YP_001461428.1 157155089 5586696 291236..291637 1 NC_009801.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 291637 crl 5586696 crl Escherichia coli E24377A DNA-binding transcriptional regulator Crl YP_001461428.1 291236 D 331111 CDS YP_001461429.1 157158194 5586653 complement(291676..292731) 1 NC_009801.1 identified by similarity to SP:P02932; match to protein family HMM PF00267; match to protein family HMM TIGR03304; outer membrane phosphoporin protein E 292731 phoE 5586653 phoE Escherichia coli E24377A outer membrane phosphoporin protein E YP_001461429.1 291676 R 331111 CDS YP_001461430.1 157158821 5586824 293019..294122 1 NC_009801.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 294122 proB 5586824 proB Escherichia coli E24377A gamma-glutamyl kinase YP_001461430.1 293019 D 331111 CDS YP_001461431.1 157157629 5586837 294134..295387 1 NC_009801.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 295387 proA 5586837 proA Escherichia coli E24377A gamma-glutamyl phosphate reductase YP_001461431.1 294134 D 331111 CDS YP_001461432.1 157155492 5589162 295804..296661 1 NC_009801.1 identified by glimmer; hypothetical protein 296661 5589162 EcE24377A_0278 Escherichia coli E24377A hypothetical protein YP_001461432.1 295804 D 331111 CDS YP_001461433.1 157155967 5586631 296783..297001 1 NC_009801.1 identified by match to protein family HMM PF05930; prophage CP4-57 regulatory protein 297001 5586631 EcE24377A_0279 Escherichia coli E24377A prophage CP4-57 regulatory protein YP_001461433.1 296783 D 331111 CDS YP_001461434.1 157154939 5590067 297108..298190 1 NC_009801.1 identified by glimmer; hypothetical protein 298190 5590067 EcE24377A_0280 Escherichia coli E24377A hypothetical protein YP_001461434.1 297108 D 331111 CDS YP_001461435.1 157158196 5586741 298177..298890 1 NC_009801.1 identified by glimmer; hypothetical protein 298890 5586741 EcE24377A_0281 Escherichia coli E24377A hypothetical protein YP_001461435.1 298177 D 331111 CDS YP_001461436.1 157155470 5586826 complement(299412..302654) 1 NC_009801.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; SNF2 family helicase 302654 5586826 EcE24377A_0282 Escherichia coli E24377A SNF2 family helicase YP_001461436.1 299412 R 331111 CDS YP_001461437.1 157154971 5590004 complement(302654..304357) 1 NC_009801.1 identified by glimmer; hypothetical protein 304357 5590004 EcE24377A_0283 Escherichia coli E24377A hypothetical protein YP_001461437.1 302654 R 331111 CDS YP_001461438.1 157156048 5586945 complement(304333..305073) 1 NC_009801.1 identified by glimmer; hypothetical protein 305073 5586945 EcE24377A_0284 Escherichia coli E24377A hypothetical protein YP_001461438.1 304333 R 331111 CDS YP_001461439.1 157155484 5588822 complement(305087..307306) 1 NC_009801.1 identified by glimmer; hypothetical protein 307306 5588822 EcE24377A_0285 Escherichia coli E24377A hypothetical protein YP_001461439.1 305087 R 331111 CDS YP_001461440.1 157157373 5586832 307639..309348 1 NC_009801.1 identified by match to protein family HMM PF02384; N4/N6-methyltransferase 309348 5586832 EcE24377A_0286 Escherichia coli E24377A N4/N6-methyltransferase YP_001461440.1 307639 D 331111 CDS YP_001461441.1 157156744 5589822 309338..310753 1 NC_009801.1 identified by match to protein family HMM PF01420; type I restriction modification DNA specificity domain-containing protein 310753 5589822 EcE24377A_0287 Escherichia coli E24377A type I restriction modification DNA specificity domain-containing protein YP_001461441.1 309338 D 331111 CDS YP_001461442.1 157158040 5588530 310746..311933 1 NC_009801.1 identified by similarity to GB:CAF28525.1; hypothetical protein 311933 5588530 EcE24377A_0288 Escherichia coli E24377A hypothetical protein YP_001461442.1 310746 D 331111 CDS YP_001461443.1 157157518 5589443 311933..315067 1 NC_009801.1 identified by similarity to GB:AAB70710.1; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM TIGR00348; HsdR family type I site-specific deoxyribonuclease 315067 5589443 EcE24377A_0289 Escherichia coli E24377A HsdR family type I site-specific deoxyribonuclease YP_001461443.1 311933 D 331111 CDS YP_001461444.1 157159365 5589702 315244..318276 1 NC_009801.1 identified by similarity to SP:P15038; match to protein family HMM PF00580; match to protein family HMM PF01396; UvrD family helicase 318276 5589702 EcE24377A_0290 Escherichia coli E24377A UvrD family helicase YP_001461444.1 315244 D 331111 CDS YP_001461445.1 157156087 5590078 318276..319091 1 NC_009801.1 identified by glimmer; hypothetical protein 319091 5590078 EcE24377A_0291 Escherichia coli E24377A hypothetical protein YP_001461445.1 318276 D 331111 CDS YP_001461446.1 157155411 5587084 complement(319243..320565) 1 NC_009801.1 identified by match to protein family HMM PF00589; phage integrase 320565 5587084 EcE24377A_0292 Escherichia coli E24377A phage integrase YP_001461446.1 319243 R 331111 CDS YP_001461447.1 157154740 5589889 complement(321291..322247) 1 NC_009801.1 identified by match to protein family HMM PF02625; xanthine dehydrogenase accessory factor 322247 5589889 EcE24377A_0294 Escherichia coli E24377A xanthine dehydrogenase accessory factor YP_001461447.1 321291 R 331111 CDS YP_001461448.1 157156885 5589074 complement(322257..324455) 1 NC_009801.1 identified by match to protein family HMM PF01315; match to protein family HMM PF02738; xanthine dehydrogenase, molybdopterin-binding subunit 324455 5589074 EcE24377A_0295 Escherichia coli E24377A xanthine dehydrogenase, molybdopterin-binding subunit YP_001461448.1 322257 R 331111 CDS YP_001461449.1 157156073 5587550 complement(324452..325408) 1 NC_009801.1 identified by match to protein family HMM PF00941; FAD binding domain-containing protein 325408 5587550 EcE24377A_0296 Escherichia coli E24377A FAD binding domain-containing protein YP_001461449.1 324452 R 331111 CDS YP_001461450.1 157158200 5586893 complement(325405..326094) 1 NC_009801.1 identified by match to protein family HMM PF00111; match to protein family HMM PF01799; match to protein family HMM TIGR01409; xanthine dehydrogenase iron-sulfur-binding subunit 326094 5586893 EcE24377A_0297 Escherichia coli E24377A xanthine dehydrogenase iron-sulfur-binding subunit YP_001461450.1 325405 R 331111 CDS YP_001461451.1 157157430 5587341 326512..327126 1 NC_009801.1 identified by match to protein family HMM PF07274; hypothetical protein 327126 5587341 EcE24377A_0298 Escherichia coli E24377A hypothetical protein YP_001461451.1 326512 D 331111 CDS YP_001461452.1 157158349 5588111 complement(328011..328721) 1 NC_009801.1 hypothetical protein 328721 5588111 EcE24377A_0299 Escherichia coli E24377A hypothetical protein YP_001461452.1 328011 R 331111 CDS YP_001461453.1 157158770 5586256 complement(328690..330333) 1 NC_009801.1 hypothetical protein 330333 5586256 EcE24377A_0300 Escherichia coli E24377A hypothetical protein YP_001461453.1 328690 R 331111 CDS YP_001461454.1 157154909 5587889 complement(330323..332848) 1 NC_009801.1 hypothetical protein 332848 5587889 EcE24377A_0301 Escherichia coli E24377A hypothetical protein YP_001461454.1 330323 R 331111 CDS YP_001461455.1 157159226 5587335 complement(332874..333542) 1 NC_009801.1 identified by similarity to GB:AAN78884.1; hypothetical protein 333542 5587335 EcE24377A_0302 Escherichia coli E24377A hypothetical protein YP_001461455.1 332874 R 331111 CDS YP_001461456.1 157155651 5589766 complement(333600..334187) 1 NC_009801.1 fimbrillin MatB 334187 matB 5589766 matB Escherichia coli E24377A fimbrillin MatB YP_001461456.1 333600 R 331111 CDS YP_001461457.1 157156152 5588119 complement(334262..334852) 1 NC_009801.1 identified by match to protein family HMM PF00196; fimbrillin MatA 334852 matA 5588119 matA Escherichia coli E24377A fimbrillin MatA YP_001461457.1 334262 R 331111 CDS YP_001461458.1 157156737 5585955 complement(335050..335145) 1 NC_009801.1 identified by glimmer; hypothetical protein 335145 5585955 EcE24377A_0305 Escherichia coli E24377A hypothetical protein YP_001461458.1 335050 R 331111 CDS YP_001461459.1 157157243 5586687 complement(335889..336029) 1 NC_009801.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 336029 rpmJ 5586687 rpmJ Escherichia coli E24377A 50S ribosomal protein L36 YP_001461459.1 335889 R 331111 CDS YP_001461460.1 157158370 5587708 complement(336029..336295) 1 NC_009801.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 336295 rpmE2 5587708 rpmE2 Escherichia coli E24377A 50S ribosomal protein L31 YP_001461460.1 336029 R 331111 CDS YP_001461461.1 157158841 5587692 336456..336548 1 NC_009801.1 identified by glimmer; hypothetical protein 336548 5587692 EcE24377A_0308 Escherichia coli E24377A hypothetical protein YP_001461461.1 336456 D 331111 CDS YP_001461462.1 157159361 5590779 complement(336656..336757) 1 NC_009801.1 identified by glimmer; hypothetical protein 336757 5590779 EcE24377A_0309 Escherichia coli E24377A hypothetical protein YP_001461462.1 336656 R 331111 CDS YP_001461463.1 157155092 5588482 336725..336838 1 NC_009801.1 identified by glimmer; hypothetical protein 336838 5588482 EcE24377A_0310 Escherichia coli E24377A hypothetical protein YP_001461463.1 336725 D 331111 CDS YP_001461464.1 157156345 5588687 complement(337864..337974) 1 NC_009801.1 identified by glimmer; hypothetical protein 337974 5588687 EcE24377A_0311 Escherichia coli E24377A hypothetical protein YP_001461464.1 337864 R 331111 CDS YP_001461465.1 157156471 5586806 337935..342125 1 NC_009801.1 identified by similarity to SP:P36943; match to protein family HMM PF02369; EaeH 342125 5586806 EcE24377A_0312 Escherichia coli E24377A EaeH YP_001461465.1 337935 D 331111 CDS YP_001461466.1 157156459 5589454 complement(342246..343103) 1 NC_009801.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445; AraC family transcriptional regulator 343103 5589454 EcE24377A_0313 Escherichia coli E24377A AraC family transcriptional regulator YP_001461466.1 342246 R 331111 CDS YP_001461467.1 157156985 5586056 343352..344221 1 NC_009801.1 identified by match to protein family HMM PF00248; aldo/keto reductase 344221 5586056 EcE24377A_0314 Escherichia coli E24377A aldo/keto reductase YP_001461467.1 343352 D 331111 CDS YP_001461468.1 157157158 5589599 complement(344381..344974) 1 NC_009801.1 identified by match to protein family HMM PF04224; hypothetical protein 344974 5589599 EcE24377A_0315 Escherichia coli E24377A hypothetical protein YP_001461468.1 344381 R 331111 CDS YP_001461470.1 157157971 5587713 complement(344986..345222) 1 NC_009801.1 identified by match to protein family HMM PF07338; hypothetical protein 345222 5587713 EcE24377A_0316 Escherichia coli E24377A hypothetical protein YP_001461470.1 344986 R 331111 CDS YP_001461471.1 157155734 5586487 complement(345331..346656) 1 NC_009801.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 346656 5586487 EcE24377A_0318 Escherichia coli E24377A pyridine nucleotide-disulfide oxidoreductase YP_001461471.1 345331 R 331111 CDS YP_001461472.1 157156451 5590796 346736..346828 1 NC_009801.1 identified by glimmer; hypothetical protein 346828 5590796 EcE24377A_0319 Escherichia coli E24377A hypothetical protein YP_001461472.1 346736 D 331111 CDS YP_001461473.1 157156998 5588078 346882..347736 1 NC_009801.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 347736 5588078 EcE24377A_0320 Escherichia coli E24377A AraC family transcriptional regulator YP_001461473.1 346882 D 331111 CDS YP_001461474.1 157156993 5586443 348263..348982 1 NC_009801.1 identified by match to protein family HMM PF02754; hypothetical protein 348982 5586443 EcE24377A_0321 Escherichia coli E24377A hypothetical protein YP_001461474.1 348263 D 331111 CDS YP_001461475.1 157159192 5588031 348993..350420 1 NC_009801.1 identified by match to protein family HMM PF02589; match to protein family HMM TIGR00273; iron-sulfur cluster binding protein 350420 5588031 EcE24377A_0322 Escherichia coli E24377A iron-sulfur cluster binding protein YP_001461475.1 348993 D 331111 CDS YP_001461476.1 157158990 5589538 350413..351108 1 NC_009801.1 identified by similarity to GB:AAP15803.1; match to protein family HMM PF02589; hypothetical protein 351108 5589538 EcE24377A_0323 Escherichia coli E24377A hypothetical protein YP_001461476.1 350413 D 331111 CDS YP_001461477.1 157157674 5590524 complement(351182..351379) 1 NC_009801.1 identified by glimmer; hypothetical protein 351379 5590524 EcE24377A_0324 Escherichia coli E24377A hypothetical protein YP_001461477.1 351182 R 331111 CDS YP_001461478.1 157155567 5588957 complement(351351..352019) 1 NC_009801.1 identified by similarity to GB:CAD02590.1; hypothetical protein 352019 5588957 EcE24377A_0325 Escherichia coli E24377A hypothetical protein YP_001461478.1 351351 R 331111 CDS YP_001461479.1 157158516 5585938 complement(352232..353902) 1 NC_009801.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 353902 betA 5585938 betA Escherichia coli E24377A choline dehydrogenase YP_001461479.1 352232 R 331111 CDS YP_001461480.1 157156812 5588779 complement(353916..355388) 1 NC_009801.1 catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 355388 betB 5588779 betB Escherichia coli E24377A betaine aldehyde dehydrogenase YP_001461480.1 353916 R 331111 CDS YP_001461481.1 157155650 5587070 complement(355402..355989) 1 NC_009801.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 355989 betI 5587070 betI Escherichia coli E24377A transcriptional regulator BetI YP_001461481.1 355402 R 331111 CDS YP_001461482.1 157156382 5588921 356127..356402 1 NC_009801.1 identified by match to protein family HMM PF03811; IS1, transposase orfA 356402 5588921 EcE24377A_0329 Escherichia coli E24377A IS1, transposase orfA YP_001461482.1 356127 D 331111 CDS YP_001461483.1 157157054 5587092 356321..356824 1 NC_009801.1 identified by match to protein family HMM PF03400; IS1, transposase orfB 356824 5587092 EcE24377A_0330 Escherichia coli E24377A IS1, transposase orfB YP_001461483.1 356321 D 331111 CDS YP_001461484.1 157158744 5587428 356894..358927 1 NC_009801.1 proton-motive-force-driven choline transporter; choline transport protein BetT 358927 betT 5587428 betT Escherichia coli E24377A choline transport protein BetT YP_001461484.1 356894 D 331111 CDS YP_001461485.1 157158257 5589482 359500..363483 1 NC_009801.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR03304; outer membrane autotransporter 363483 5589482 EcE24377A_0332 Escherichia coli E24377A outer membrane autotransporter YP_001461485.1 359500 D 331111 CDS YP_001461486.1 157158021 5589608 363625..364713 1 NC_009801.1 identified by match to protein family HMM PF00196; match to protein family HMM PF00563; LuxR family transcriptional regulator 364713 5589608 EcE24377A_0333 Escherichia coli E24377A LuxR family transcriptional regulator YP_001461486.1 363625 D 331111 CDS YP_001461487.1 157156304 5586734 complement(364755..365687) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 365687 5586734 EcE24377A_0334 Escherichia coli E24377A LysR family transcriptional regulator YP_001461487.1 364755 R 331111 CDS YP_001461488.1 157159229 5587773 complement(365779..366276) 1 NC_009801.1 identified by similarity to SP:P77219; match to protein family HMM PF06496; hypothetical protein 366276 5587773 EcE24377A_0335 Escherichia coli E24377A hypothetical protein YP_001461488.1 365779 R 331111 CDS YP_001461489.1 157157384 5586797 366353..366586 1 NC_009801.1 identified by similarity to GB:AAN78919.1; hypothetical protein 366586 5586797 EcE24377A_0336 Escherichia coli E24377A hypothetical protein YP_001461489.1 366353 D 331111 CDS YP_001461490.1 157155799 5589653 366534..367139 1 NC_009801.1 identified by match to protein family HMM PF00023; ankyrin repeat-containing protein 367139 5589653 EcE24377A_0337 Escherichia coli E24377A ankyrin repeat-containing protein YP_001461490.1 366534 D 331111 CDS YP_001461491.1 157158698 5587514 367179..368042 1 NC_009801.1 identified by similarity to GB:AAZ87092.1; hypothetical protein 368042 5587514 EcE24377A_0338 Escherichia coli E24377A hypothetical protein YP_001461491.1 367179 D 331111 CDS YP_001461492.1 157154800 5589184 368032..369579 1 NC_009801.1 identified by match to protein family HMM PF06263; acyl-CoA synthetase 369579 5589184 EcE24377A_0339 Escherichia coli E24377A acyl-CoA synthetase YP_001461492.1 368032 D 331111 CDS YP_001461493.1 157155327 5587584 369579..370997 1 NC_009801.1 identified by match to protein family HMM PF06545; hypothetical protein 370997 5587584 EcE24377A_0340 Escherichia coli E24377A hypothetical protein YP_001461493.1 369579 D 331111 CDS YP_001461494.1 157157266 5588053 371140..372090 1 NC_009801.1 yahI; identified by match to protein family HMM PF00696; carbamate kinase 372090 5588053 EcE24377A_0341 Escherichia coli E24377A carbamate kinase YP_001461494.1 371140 D 331111 CDS YP_001461495.1 157155685 5587877 372238..373482 1 NC_009801.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; deaminase 373482 5587877 EcE24377A_0342 Escherichia coli E24377A deaminase YP_001461495.1 372238 D 331111 CDS YP_001461496.1 157157414 5589221 373751..374191 1 NC_009801.1 identified by match to protein family HMM PF06171; hypothetical protein 374191 5589221 EcE24377A_0343 Escherichia coli E24377A hypothetical protein YP_001461496.1 373751 D 331111 CDS YP_001461497.1 157159464 5589017 complement(374219..374320) 1 NC_009801.1 identified by glimmer; hypothetical protein 374320 5589017 EcE24377A_0344 Escherichia coli E24377A hypothetical protein YP_001461497.1 374219 R 331111 CDS YP_001461498.1 157156551 5586125 374445..375428 1 NC_009801.1 sugar ABC transporter periplasmic sugar-binding protein 375428 5586125 EcE24377A_0345 Escherichia coli E24377A sugar ABC transporter periplasmic sugar-binding protein YP_001461498.1 374445 D 331111 CDS YP_001461499.1 157156018 5586408 375477..376961 1 NC_009801.1 identified by match to protein family HMM PF00005; sugar ABC transporter ATP-binding protein 376961 5586408 EcE24377A_0346 Escherichia coli E24377A sugar ABC transporter ATP-binding protein YP_001461499.1 375477 D 331111 CDS YP_001461500.1 157156768 5589893 376954..377925 1 NC_009801.1 identified by match to protein family HMM PF02653; sugar ABC transporter permease 377925 5589893 EcE24377A_0347 Escherichia coli E24377A sugar ABC transporter permease YP_001461500.1 376954 D 331111 CDS YP_001461501.1 157156045 5589544 377922..378878 1 NC_009801.1 identified by match to protein family HMM PF02653; sugar ABC transporter permease 378878 5589544 EcE24377A_0348 Escherichia coli E24377A sugar ABC transporter permease YP_001461501.1 377922 D 331111 CDS YP_001461502.1 157155687 5585944 378965..380014 1 NC_009801.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; zinc-binding dehydrogenase oxidoreductase 380014 5585944 EcE24377A_0349 Escherichia coli E24377A zinc-binding dehydrogenase oxidoreductase YP_001461502.1 378965 D 331111 CDS YP_001461503.1 157154994 5588763 380257..381072 1 NC_009801.1 identified by similarity to GB:AAZ87085.1; hypothetical protein 381072 5588763 EcE24377A_0350 Escherichia coli E24377A hypothetical protein YP_001461503.1 380257 D 331111 CDS YP_001461504.1 157159412 5586551 complement(381746..382393) 1 NC_009801.1 yahN; identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949; homoserine/threonine efflux protein 382393 5586551 EcE24377A_0352 Escherichia coli E24377A homoserine/threonine efflux protein YP_001461504.1 381746 R 331111 CDS YP_001461505.1 157156208 5586129 382564..382839 1 NC_009801.1 identified by match to protein family HMM PF07338; hypothetical protein 382839 5586129 EcE24377A_0353 Escherichia coli E24377A hypothetical protein YP_001461505.1 382564 D 331111 CDS YP_001461506.1 157159324 5587781 complement(382937..384523) 1 NC_009801.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF06506; match to protein family HMM TIGR02329; propionate catabolism operon regulatory protein PrpR 384523 prpR 5587781 prpR Escherichia coli E24377A propionate catabolism operon regulatory protein PrpR YP_001461506.1 382937 R 331111 CDS YP_001461507.1 157158609 5586247 384584..384682 1 NC_009801.1 identified by glimmer; hypothetical protein 384682 5586247 EcE24377A_0355 Escherichia coli E24377A hypothetical protein YP_001461507.1 384584 D 331111 CDS YP_001461508.1 157158231 5586993 384761..385651 1 NC_009801.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 385651 prpB 5586993 prpB Escherichia coli E24377A 2-methylisocitrate lyase YP_001461508.1 384761 D 331111 CDS YP_001461509.1 157157579 5589480 385696..386865 1 NC_009801.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 386865 prpC 5589480 prpC Escherichia coli E24377A methylcitrate synthase YP_001461509.1 385696 D 331111 CDS YP_001461510.1 157158262 5589012 386899..388350 1 NC_009801.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 388350 prpD 5589012 prpD Escherichia coli E24377A 2-methylcitrate dehydratase YP_001461510.1 386899 D 331111 CDS YP_001461511.1 157157602 5587777 388390..390276 1 NC_009801.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 390276 prpE 5587777 prpE Escherichia coli E24377A propionyl-CoA synthetase YP_001461511.1 388390 D 331111 CDS YP_001461512.1 157156666 5589477 390513..391772 1 NC_009801.1 identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800; cytosine permease 391772 codB 5589477 codB Escherichia coli E24377A cytosine permease YP_001461512.1 390513 D 331111 CDS YP_001461513.1 157156161 5588598 391762..393045 1 NC_009801.1 Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 393045 codA 5588598 codA Escherichia coli E24377A cytosine deaminase YP_001461513.1 391762 D 331111 CDS YP_001461514.1 157155582 5590826 complement(393085..393984) 1 NC_009801.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source; DNA-binding transcriptional regulator CynR 393984 cynR 5590826 cynR Escherichia coli E24377A DNA-binding transcriptional regulator CynR YP_001461514.1 393085 R 331111 CDS YP_001461515.1 157155049 5587309 393907..394002 1 NC_009801.1 identified by glimmer; hypothetical protein 394002 5587309 EcE24377A_0363 Escherichia coli E24377A hypothetical protein YP_001461515.1 393907 D 331111 CDS YP_001461516.1 157157076 5585900 394094..394753 1 NC_009801.1 identified by match to protein family HMM PF00484; carbonic anhydrase 394753 cynT 5585900 cynT Escherichia coli E24377A carbonic anhydrase YP_001461516.1 394094 D 331111 CDS YP_001461517.1 157157752 5588730 394784..395254 1 NC_009801.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase 395254 cynS 5588730 cynS Escherichia coli E24377A cyanate hydratase YP_001461517.1 394784 D 331111 CDS YP_001461518.1 157155715 5587185 395287..396441 1 NC_009801.1 MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential; cyanate transporter 396441 cynX 5587185 cynX Escherichia coli E24377A cyanate transporter YP_001461518.1 395287 D 331111 CDS YP_001461519.1 157156415 5588591 complement(396520..397773) 1 NC_009801.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 397773 lacY 5588591 lacY Escherichia coli E24377A galactoside permease YP_001461519.1 396520 R 331111 CDS YP_001461520.1 157154977 5589745 complement(397825..400899) 1 NC_009801.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase 400899 lacZ 5589745 lacZ Escherichia coli E24377A beta-D-galactosidase YP_001461520.1 397825 R 331111 CDS YP_001461521.1 157155643 5588695 complement(401022..402113) 1 NC_009801.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor 402113 lacI 5588695 lacI Escherichia coli E24377A lac repressor YP_001461521.1 401022 R 331111 CDS YP_001461522.1 157158422 5588644 complement(402181..403128) 1 NC_009801.1 activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional activator MhpR 403128 mhpR 5588644 mhpR Escherichia coli E24377A DNA-binding transcriptional activator MhpR YP_001461522.1 402181 R 331111 CDS YP_001461523.1 157159034 5589374 403205..404869 1 NC_009801.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase 404869 mhpA 5589374 mhpA Escherichia coli E24377A 3-(3-hydroxyphenyl)propionate hydroxylase YP_001461523.1 403205 D 331111 CDS YP_001461524.1 157157662 5589309 404871..405815 1 NC_009801.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase; 3-(2,3-dihydroxyphenyl)propionate dioxygenase 405815 mhpB 5589309 mhpB Escherichia coli E24377A 3-(2,3-dihydroxyphenyl)propionate dioxygenase YP_001461524.1 404871 D 331111 CDS YP_001461525.1 157155601 5590082 405818..406699 1 NC_009801.1 identified by similarity to SP:P77044; match to protein family HMM PF00561; 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase 406699 mhpC 5590082 mhpC Escherichia coli E24377A 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase YP_001461525.1 405818 D 331111 CDS YP_001461526.1 157156243 5587540 406709..407518 1 NC_009801.1 catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid; 2-keto-4-pentenoate hydratase 407518 mhpD 5587540 mhpD Escherichia coli E24377A 2-keto-4-pentenoate hydratase YP_001461526.1 406709 D 331111 CDS YP_001461527.1 157156149 5586084 407515..408465 1 NC_009801.1 catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase 408465 mhpF 5586084 mhpF Escherichia coli E24377A acetaldehyde dehydrogenase YP_001461527.1 407515 D 331111 CDS YP_001461528.1 157155206 5587752 408462..409475 1 NC_009801.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 409475 mhpE 5587752 mhpE Escherichia coli E24377A 4-hydroxy-2-ketovalerate aldolase YP_001461528.1 408462 D 331111 CDS YP_001461529.1 157155702 5587560 409651..410862 1 NC_009801.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00895; 3-hydroxyphenylpropionic transporter MhpT 410862 5587560 EcE24377A_0377 Escherichia coli E24377A 3-hydroxyphenylpropionic transporter MhpT YP_001461529.1 409651 D 331111 CDS YP_001461530.1 157158343 5590242 410964..411503 1 NC_009801.1 hypothetical protein 411503 5590242 EcE24377A_0378 Escherichia coli E24377A hypothetical protein YP_001461530.1 410964 D 331111 CDS YP_001461531.1 157159466 5589137 411525..411632 1 NC_009801.1 identified by glimmer; hypothetical protein 411632 5589137 EcE24377A_0379 Escherichia coli E24377A hypothetical protein YP_001461531.1 411525 D 331111 CDS YP_001461532.1 157157121 5587379 complement(411729..412562) 1 NC_009801.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821; S-formylglutathione hydrolase 412562 fghA1 5587379 fghA1 Escherichia coli E24377A S-formylglutathione hydrolase YP_001461532.1 411729 R 331111 CDS YP_001461533.1 157155527 5590872 complement(412655..413764) 1 NC_009801.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818; alcohol dehydrogenase 413764 5590872 EcE24377A_0381 Escherichia coli E24377A alcohol dehydrogenase YP_001461533.1 412655 R 331111 CDS YP_001461534.1 157158905 5587587 complement(413799..414074) 1 NC_009801.1 formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR 414074 5587587 EcE24377A_0382 Escherichia coli E24377A regulator protein FrmR YP_001461534.1 413799 R 331111 CDS YP_001461535.1 157156597 5587034 complement(414260..415033) 1 NC_009801.1 yaiO; identified by glimmer; hypothetical protein 415033 5587034 EcE24377A_0383 Escherichia coli E24377A hypothetical protein YP_001461535.1 414260 R 331111 CDS YP_001461536.1 157157408 5586266 complement(415035..415475) 1 NC_009801.1 identified by match to protein family HMM PF00132; acyltransferase 415475 5586266 EcE24377A_0384 Escherichia coli E24377A acyltransferase YP_001461536.1 415035 R 331111 CDS YP_001461537.1 157155529 5588509 complement(415594..416790) 1 NC_009801.1 yaiP; identified by match to protein family HMM PF00535; glycosyl transferase family protein 416790 5588509 EcE24377A_0385 Escherichia coli E24377A glycosyl transferase family protein YP_001461537.1 415594 R 331111 CDS YP_001461538.1 157156377 5587589 complement(416800..417471) 1 NC_009801.1 yaiS; identified by match to protein family HMM PF02585; GlcNAc-PI de-N-acetylase 417471 5587589 EcE24377A_0386 Escherichia coli E24377A GlcNAc-PI de-N-acetylase YP_001461538.1 416800 R 331111 CDS YP_001461539.1 157158716 5590610 417643..417750 1 NC_009801.1 identified by glimmer; hypothetical protein 417750 5590610 EcE24377A_0387 Escherichia coli E24377A hypothetical protein YP_001461539.1 417643 D 331111 CDS YP_001461540.1 157159237 5589304 complement(417909..418133) 1 NC_009801.1 identified by glimmer; hypothetical protein 418133 5589304 EcE24377A_0388 Escherichia coli E24377A hypothetical protein YP_001461540.1 417909 R 331111 CDS YP_001461541.1 157157826 5586558 418087..419049 1 NC_009801.1 with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 419049 tauA 5586558 tauA Escherichia coli E24377A taurine transporter substrate binding subunit YP_001461541.1 418087 D 331111 CDS YP_001461542.1 157157564 5586630 419825..420652 1 NC_009801.1 identified by match to protein family HMM PF00528; taurine transporter subunit 420652 tauC 5586630 tauC Escherichia coli E24377A taurine transporter subunit YP_001461542.1 419825 D 331111 CDS YP_001461543.1 157156427 5588471 420649..421500 1 NC_009801.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 421500 tauD 5588471 tauD Escherichia coli E24377A taurine dioxygenase YP_001461543.1 420649 D 331111 CDS YP_001461544.1 157156861 5586710 complement(421658..422632) 1 NC_009801.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 422632 hemB 5586710 hemB Escherichia coli E24377A delta-aminolevulinic acid dehydratase YP_001461544.1 421658 R 331111 CDS YP_001461545.1 157155082 5589325 complement(423338..424243) 1 NC_009801.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 424243 5589325 EcE24377A_0394 Escherichia coli E24377A insertion element IS2 transposase InsD YP_001461545.1 423338 R 331111 CDS YP_001461546.1 157154869 5588506 complement(424201..424566) 1 NC_009801.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 424566 5588506 EcE24377A_0395 Escherichia coli E24377A insertion sequence 2 OrfA protein YP_001461546.1 424201 R 331111 CDS YP_001461547.1 157157315 5589161 424630..427398 1 NC_009801.1 identified by match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR03304; outer membrane autotransporter 427398 5589161 EcE24377A_0396 Escherichia coli E24377A outer membrane autotransporter YP_001461547.1 424630 D 331111 CDS YP_001461548.1 157158707 5587377 427486..428109 1 NC_009801.1 identified by similarity to SP:P0AAP5; DNA-binding transcriptional regulator 428109 5587377 EcE24377A_0397 Escherichia coli E24377A DNA-binding transcriptional regulator YP_001461548.1 427486 D 331111 CDS YP_001461549.1 157156874 5590812 complement(428110..429267) 1 NC_009801.1 this protein has no known enzymatic function; beta-lactam binding protein AmpH 429267 ampH 5590812 ampH Escherichia coli E24377A beta-lactam binding protein AmpH YP_001461549.1 428110 R 331111 CDS YP_001461550.1 157157661 5587833 complement(429313..429414) 1 NC_009801.1 identified by glimmer; hypothetical protein 429414 5587833 EcE24377A_0399 Escherichia coli E24377A hypothetical protein YP_001461550.1 429313 R 331111 CDS YP_001461551.1 157155278 5590081 429405..429599 1 NC_009801.1 identified by glimmer; hypothetical protein 429599 5590081 EcE24377A_0400 Escherichia coli E24377A hypothetical protein YP_001461551.1 429405 D 331111 CDS YP_001461552.1 157156455 5590494 429619..430839 1 NC_009801.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 430839 smbA 5590494 smbA Escherichia coli E24377A transporter YP_001461552.1 429619 D 331111 CDS YP_001461553.1 157157309 5589316 430852..431946 1 NC_009801.1 identified by match to protein family HMM PF07759; lipoprotein 431946 5589316 EcE24377A_0402 Escherichia coli E24377A lipoprotein YP_001461553.1 430852 D 331111 CDS YP_001461554.1 157158985 5589474 complement(431947..432051) 1 NC_009801.1 identified by glimmer; hypothetical protein 432051 5589474 EcE24377A_0403 Escherichia coli E24377A hypothetical protein YP_001461554.1 431947 R 331111 CDS YP_001461555.1 157158624 5588208 complement(432005..432313) 1 NC_009801.1 identified by similarity to SP:P0AAP7; hypothetical protein 432313 5588208 EcE24377A_0404 Escherichia coli E24377A hypothetical protein YP_001461555.1 432005 R 331111 CDS YP_001461556.1 157154885 5587268 432441..432785 1 NC_009801.1 identified by similarity to GB:AAZ87131.1; hypothetical protein 432785 5587268 EcE24377A_0405 Escherichia coli E24377A hypothetical protein YP_001461556.1 432441 D 331111 CDS YP_001461557.1 157155036 5587949 complement(432809..433903) 1 NC_009801.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 433903 ddl 5587949 ddl Escherichia coli E24377A D-alanyl-alanine synthetase A YP_001461557.1 432809 R 331111 CDS YP_001461558.1 157155189 5589987 433984..434184 1 NC_009801.1 identified by glimmer; hypothetical protein 434184 5589987 EcE24377A_0407 Escherichia coli E24377A hypothetical protein YP_001461558.1 433984 D 331111 CDS YP_001461559.1 157156970 5588651 434207..434320 1 NC_009801.1 identified by glimmer; hypothetical protein 434320 5588651 EcE24377A_0408 Escherichia coli E24377A hypothetical protein YP_001461559.1 434207 D 331111 CDS YP_001461560.1 157157736 5587333 434366..434626 1 NC_009801.1 hypothetical protein 434626 5587333 EcE24377A_0409 Escherichia coli E24377A hypothetical protein YP_001461560.1 434366 D 331111 CDS YP_001461561.1 157156143 5590008 434727..436142 1 NC_009801.1 identified by similarity to SP:P00634; match to protein family HMM PF00245; alkaline phosphatase 436142 phoA 5590008 phoA Escherichia coli E24377A alkaline phosphatase YP_001461561.1 434727 D 331111 CDS YP_001461562.1 157157063 5589113 436261..436581 1 NC_009801.1 identified by match to protein family HMM PF07769; hypothetical protein 436581 psiF 5589113 psiF Escherichia coli E24377A hypothetical protein YP_001461562.1 436261 D 331111 CDS YP_001461563.1 157157429 5585979 436683..437798 1 NC_009801.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 437798 adrA 5585979 adrA Escherichia coli E24377A diguanylate cyclase AdrA YP_001461563.1 436683 D 331111 CDS YP_001461564.1 157157179 5588373 complement(437815..438624) 1 NC_009801.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 438624 proC 5588373 proC Escherichia coli E24377A pyrroline-5-carboxylate reductase YP_001461564.1 437815 R 331111 CDS YP_001461565.1 157157816 5590534 438744..439202 1 NC_009801.1 identified by similarity to SP:Q3Z523; match to protein family HMM PF02639; hypothetical protein 439202 5590534 EcE24377A_0414 Escherichia coli E24377A hypothetical protein YP_001461565.1 438744 D 331111 CDS YP_001461566.1 157158472 5589344 439385..439909 1 NC_009801.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 439909 aroL 5589344 aroL Escherichia coli E24377A shikimate kinase YP_001461566.1 439385 D 331111 CDS YP_001461567.1 157159121 5590701 439959..440150 1 NC_009801.1 hypothetical protein 440150 5590701 EcE24377A_0416 Escherichia coli E24377A hypothetical protein YP_001461567.1 439959 D 331111 CDS YP_001461568.1 157155263 5588502 440408..441085 1 NC_009801.1 identified by match to protein family HMM PF07302; hypothetical protein 441085 aroM 5588502 aroM Escherichia coli E24377A hypothetical protein YP_001461568.1 440408 D 331111 CDS YP_001461569.1 157155801 5588992 441157..441441 1 NC_009801.1 identified by match to protein family HMM PF06865; hypothetical protein 441441 5588992 EcE24377A_0418 Escherichia coli E24377A hypothetical protein YP_001461569.1 441157 D 331111 CDS YP_001461570.1 157155471 5590383 441649..441930 1 NC_009801.1 ykiA; identified by glimmer; hypothetical protein 441930 5590383 EcE24377A_0419 Escherichia coli E24377A hypothetical protein YP_001461570.1 441649 D 331111 CDS YP_001461571.1 157156282 5588613 complement(442088..442999) 1 NC_009801.1 Required for efficient pilin antigenic variation; recombination associated protein 442999 rdgC 5588613 rdgC Escherichia coli E24377A recombination associated protein YP_001461571.1 442088 R 331111 CDS YP_001461572.1 157155583 5590169 443124..444032 1 NC_009801.1 catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 444032 mak 5590169 mak Escherichia coli E24377A fructokinase YP_001461572.1 443124 D 331111 CDS YP_001461573.1 157157314 5590361 444011..444151 1 NC_009801.1 identified by glimmer; hypothetical protein 444151 5590361 EcE24377A_0422 Escherichia coli E24377A hypothetical protein YP_001461573.1 444011 D 331111 CDS YP_001461574.1 157156635 5590114 complement(444175..445443) 1 NC_009801.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ 445443 araJ 5590114 araJ Escherichia coli E24377A MFS transport protein AraJ YP_001461574.1 444175 R 331111 CDS YP_001461575.1 157155185 5590405 complement(445485..448628) 1 NC_009801.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease SbcC 448628 sbcC 5590405 sbcC Escherichia coli E24377A exonuclease SbcC YP_001461575.1 445485 R 331111 CDS YP_001461576.1 157155893 5586171 complement(448625..449827) 1 NC_009801.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease SbcD 449827 sbcD 5586171 sbcD Escherichia coli E24377A exonuclease SbcD YP_001461576.1 448625 R 331111 CDS YP_001461577.1 157155254 5587783 449813..449944 1 NC_009801.1 identified by glimmer; hypothetical protein 449944 5587783 EcE24377A_0426 Escherichia coli E24377A hypothetical protein YP_001461577.1 449813 D 331111 CDS YP_001461578.1 157154834 5589223 450017..450706 1 NC_009801.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 450706 phoB 5589223 phoB Escherichia coli E24377A transcriptional regulator PhoB YP_001461578.1 450017 D 331111 CDS YP_001461579.1 157156979 5586229 450764..452059 1 NC_009801.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 452059 phoR 5586229 phoR Escherichia coli E24377A phosphate regulon sensor protein YP_001461579.1 450764 D 331111 CDS YP_001461580.1 157156340 5590209 complement(452070..452180) 1 NC_009801.1 identified by glimmer; hypothetical protein 452180 5590209 EcE24377A_0429 Escherichia coli E24377A hypothetical protein YP_001461580.1 452070 R 331111 CDS YP_001461581.1 157157424 5587171 complement(452272..452421) 1 NC_009801.1 identified by similarity to GB:AAX64346.1; hypothetical protein 452421 5587171 EcE24377A_0430 Escherichia coli E24377A hypothetical protein YP_001461581.1 452272 R 331111 CDS YP_001461582.1 157158066 5588485 452466..453785 1 NC_009801.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 453785 brnQ 5588485 brnQ Escherichia coli E24377A branched-chain amino acid transport system II carrier protein YP_001461582.1 452466 D 331111 CDS YP_001461583.1 157155440 5589530 453861..455234 1 NC_009801.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; proline-specific permease 455234 proY 5589530 proY Escherichia coli E24377A proline-specific permease YP_001461583.1 453861 D 331111 CDS YP_001461584.1 157156114 5588632 455390..457207 1 NC_009801.1 identified by similarity to SP:P21517; match to protein family HMM PF00128; maltodextrin glucosidase 457207 malZ 5588632 malZ Escherichia coli E24377A maltodextrin glucosidase YP_001461584.1 455390 D 331111 CDS YP_001461585.1 157159411 5590041 complement(457212..457793) 1 NC_009801.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; ACP phosphodieterase 457793 acpH 5590041 acpH Escherichia coli E24377A ACP phosphodieterase YP_001461585.1 457212 R 331111 CDS YP_001461586.1 157154716 5586128 457886..458956 1 NC_009801.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 458956 queA 5586128 queA Escherichia coli E24377A S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_001461586.1 457886 D 331111 CDS YP_001461587.1 157158225 5586334 459012..460139 1 NC_009801.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 460139 tgt 5586334 tgt Escherichia coli E24377A queuine tRNA-ribosyltransferase YP_001461587.1 459012 D 331111 CDS YP_001461588.1 157158712 5588231 460162..460494 1 NC_009801.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 460494 yajC 5588231 yajC Escherichia coli E24377A preprotein translocase subunit YajC YP_001461588.1 460162 D 331111 CDS YP_001461589.1 157156778 5589957 460522..462369 1 NC_009801.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 462369 secD 5589957 secD Escherichia coli E24377A preprotein translocase subunit SecD YP_001461589.1 460522 D 331111 CDS YP_001461590.1 157156867 5589142 462380..463351 1 NC_009801.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 463351 secF 5589142 secF Escherichia coli E24377A preprotein translocase subunit SecF YP_001461590.1 462380 D 331111 CDS YP_001461591.1 157159181 5588070 463480..463827 1 NC_009801.1 identified by match to protein family HMM PF01844; hypothetical protein 463827 5588070 EcE24377A_0440 Escherichia coli E24377A hypothetical protein YP_001461591.1 463480 D 331111 CDS YP_001461592.1 157158342 5586954 463841..463963 1 NC_009801.1 identified by similarity to GB:ABB67500.1; hypothetical protein 463963 5586954 EcE24377A_0441 Escherichia coli E24377A hypothetical protein YP_001461592.1 463841 D 331111 CDS YP_001461593.1 157157758 5587483 complement(464004..464888) 1 NC_009801.1 identified by match to protein family HMM PF03502; nucleoside-specific channel-forming protein 464888 tsx 5587483 tsx Escherichia coli E24377A nucleoside-specific channel-forming protein YP_001461593.1 464004 R 331111 CDS YP_001461594.1 157158172 5586766 complement(465187..465726) 1 NC_009801.1 hypothetical protein 465726 5586766 EcE24377A_0443 Escherichia coli E24377A hypothetical protein YP_001461594.1 465187 R 331111 CDS YP_001461595.1 157157082 5588868 465877..466326 1 NC_009801.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244; transcriptional regulator NrdR 466326 nrdR 5588868 nrdR Escherichia coli E24377A transcriptional regulator NrdR YP_001461595.1 465877 D 331111 CDS YP_001461596.1 157156281 5589523 466330..467433 1 NC_009801.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 467433 ribD 5589523 ribD Escherichia coli E24377A bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase YP_001461596.1 466330 D 331111 CDS YP_001461597.1 157155552 5590168 467522..467992 1 NC_009801.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 467992 ribH 5590168 ribH Escherichia coli E24377A 6,7-dimethyl-8-ribityllumazine synthase YP_001461597.1 467522 D 331111 CDS YP_001461598.1 157154883 5586262 468012..468431 1 NC_009801.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 468431 nusB 5586262 nusB Escherichia coli E24377A transcription antitermination protein NusB YP_001461598.1 468012 D 331111 CDS YP_001461599.1 157157291 5586076 468509..469486 1 NC_009801.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 469486 thiL 5586076 thiL Escherichia coli E24377A thiamine monophosphate kinase YP_001461599.1 468509 D 331111 CDS YP_001461600.1 157159287 5589979 469464..469982 1 NC_009801.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 469982 pgpA 5589979 pgpA Escherichia coli E24377A phosphatidylglycerophosphatase A YP_001461600.1 469464 D 331111 CDS YP_001461601.1 157159069 5588172 complement(470036..471010) 1 NC_009801.1 identified by match to protein family HMM PF00248; aldo/keto reductase 471010 5588172 EcE24377A_0450 Escherichia coli E24377A aldo/keto reductase YP_001461601.1 470036 R 331111 CDS YP_001461602.1 157158400 5590521 complement(471190..473052) 1 NC_009801.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 473052 dxs 5590521 dxs Escherichia coli E24377A 1-deoxy-D-xylulose-5-phosphate synthase YP_001461602.1 471190 R 331111 CDS YP_001461603.1 157155867 5586364 complement(473077..473976) 1 NC_009801.1 identified by similarity to SP:P22939; match to protein family HMM PF00348; geranyltranstransferase 473976 ispA 5586364 ispA Escherichia coli E24377A geranyltranstransferase YP_001461603.1 473077 R 331111 CDS YP_001461604.1 157155184 5588325 complement(473976..474218) 1 NC_009801.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 474218 xseB 5588325 xseB Escherichia coli E24377A exodeoxyribonuclease VII small subunit YP_001461604.1 473976 R 331111 CDS YP_001461605.1 157157596 5589650 474306..474398 1 NC_009801.1 identified by glimmer; hypothetical protein 474398 5589650 EcE24377A_0454 Escherichia coli E24377A hypothetical protein YP_001461605.1 474306 D 331111 CDS YP_001461606.1 157156951 5587958 474424..475872 1 NC_009801.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 475872 thiI 5587958 thiI Escherichia coli E24377A thiamine biosynthesis protein ThiI YP_001461606.1 474424 D 331111 CDS YP_001461607.1 157158639 5590685 complement(475926..476516) 1 NC_009801.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383; DJ-1 family protein 476516 thiJ 5590685 thiJ Escherichia coli E24377A DJ-1 family protein YP_001461607.1 475926 R 331111 CDS YP_001461608.1 157157390 5585898 complement(476479..477390) 1 NC_009801.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 477390 panE 5585898 panE Escherichia coli E24377A 2-dehydropantoate 2-reductase YP_001461608.1 476479 R 331111 CDS YP_001461609.1 157154841 5590745 477558..478049 1 NC_009801.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 478049 5590745 EcE24377A_0458 Escherichia coli E24377A nucleotide-binding protein YP_001461609.1 477558 D 331111 CDS YP_001461610.1 157159049 5589026 complement(478177..479541) 1 NC_009801.1 identified by match to protein family HMM PF07690; major facilitator transporter 479541 5589026 EcE24377A_0459 Escherichia coli E24377A major facilitator transporter YP_001461610.1 478177 R 331111 CDS YP_001461611.1 157158509 5588697 479889..480884 1 NC_009801.1 identified by match to protein family HMM PF08238; hypothetical protein 480884 5588697 EcE24377A_0460 Escherichia coli E24377A hypothetical protein YP_001461611.1 479889 D 331111 CDS YP_001461612.1 157155700 5589281 complement(480940..481482) 1 NC_009801.1 identified by match to protein family HMM PF00583; acetyltransferase 481482 5589281 EcE24377A_0461 Escherichia coli E24377A acetyltransferase YP_001461612.1 480940 R 331111 CDS YP_001461613.1 157157185 5587656 complement(481466..481825) 1 NC_009801.1 identified by similarity to GB:AAZ87186.1; match to protein family HMM PF08681; hypothetical protein 481825 5587656 EcE24377A_0462 Escherichia coli E24377A hypothetical protein YP_001461613.1 481466 R 331111 CDS YP_001461614.1 157159172 5587317 complement(481962..482852) 1 NC_009801.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 482852 cyoE 5587317 cyoE Escherichia coli E24377A protoheme IX farnesyltransferase YP_001461614.1 481962 R 331111 CDS YP_001461615.1 157157013 5587968 complement(482864..483193) 1 NC_009801.1 identified by similarity to SP:P0ABJ6; match to protein family HMM PF03626; match to protein family HMM TIGR02847; cytochrome o ubiquinol oxidase subunit IV 483193 cyoD 5587968 cyoD Escherichia coli E24377A cytochrome o ubiquinol oxidase subunit IV YP_001461615.1 482864 R 331111 CDS YP_001461616.1 157157815 5589290 complement(483193..483807) 1 NC_009801.1 identified by similarity to SP:P0ABJ3; match to protein family HMM PF00510; match to protein family HMM TIGR02842; cytochrome o ubiquinol oxidase subunit III 483807 cyoC 5589290 cyoC Escherichia coli E24377A cytochrome o ubiquinol oxidase subunit III YP_001461616.1 483193 R 331111 CDS YP_001461617.1 157155647 5589343 complement(483797..485788) 1 NC_009801.1 identified by match to protein family HMM PF00115; match to protein family HMM TIGR02843; cytochrome o ubiquinol oxidase subunit I 485788 cyoB 5589343 cyoB Escherichia coli E24377A cytochrome o ubiquinol oxidase subunit I YP_001461617.1 483797 R 331111 CDS YP_001461618.1 157155280 5588825 complement(485810..486757) 1 NC_009801.1 identified by similarity to SP:P0ABJ1; match to protein family HMM PF00116; match to protein family HMM PF06481; match to protein family HMM TIGR01433; cytochrome o ubiquinol oxidase subunit II 486757 cyoA 5588825 cyoA Escherichia coli E24377A cytochrome o ubiquinol oxidase subunit II YP_001461618.1 485810 R 331111 CDS YP_001461619.1 157155361 5588646 complement(487218..488693) 1 NC_009801.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 488693 ampG 5588646 ampG Escherichia coli E24377A muropeptide transporter YP_001461619.1 487218 R 331111 CDS YP_001461620.1 157154980 5590051 complement(488737..489315) 1 NC_009801.1 identified by match to protein family HMM PF03923; hypothetical protein 489315 5590051 EcE24377A_0469 Escherichia coli E24377A hypothetical protein YP_001461620.1 488737 R 331111 CDS YP_001461621.1 157155498 5590556 489620..489937 1 NC_009801.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 489937 5590556 EcE24377A_0470 Escherichia coli E24377A transcriptional regulator BolA YP_001461621.1 489620 D 331111 CDS YP_001461622.1 157154997 5590036 489946..490134 1 NC_009801.1 identified by glimmer; hypothetical protein 490134 5590036 EcE24377A_0471 Escherichia coli E24377A hypothetical protein YP_001461622.1 489946 D 331111 CDS YP_001461623.1 157155935 5587741 490281..491579 1 NC_009801.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 491579 tig 5587741 tig Escherichia coli E24377A trigger factor YP_001461623.1 490281 D 331111 CDS YP_001461624.1 157158299 5588301 491825..492448 1 NC_009801.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 492448 clpP 5588301 clpP Escherichia coli E24377A ATP-dependent Clp protease proteolytic subunit YP_001461624.1 491825 D 331111 CDS YP_001461625.1 157157655 5587882 492574..493848 1 NC_009801.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 493848 clpX 5587882 clpX Escherichia coli E24377A ATP-dependent protease ATP-binding subunit ClpX YP_001461625.1 492574 D 331111 CDS YP_001461626.1 157159434 5586073 494036..496390 1 NC_009801.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR00763; DNA-binding ATP-dependent protease La 496390 lon 5586073 lon Escherichia coli E24377A DNA-binding ATP-dependent protease La YP_001461626.1 494036 D 331111 CDS YP_001461627.1 157158595 5587651 496599..496871 1 NC_009801.1 histone-like DNA-binding protein; transcriptional regulator HU subunit beta 496871 hupB 5587651 hupB Escherichia coli E24377A transcriptional regulator HU subunit beta YP_001461627.1 496599 D 331111 CDS YP_001461628.1 157156448 5589853 497063..498934 1 NC_009801.1 identified by similarity to SP:P0ADY1; match to protein family HMM PF00639; match to protein family HMM PF09312; peptidyl-prolyl cis-trans isomerase 498934 ppiD 5589853 ppiD Escherichia coli E24377A peptidyl-prolyl cis-trans isomerase YP_001461628.1 497063 D 331111 CDS YP_001461629.1 157156949 5587687 499085..499456 1 NC_009801.1 identified by match to protein family HMM TIGR00426; competence protein ComEA 499456 5587687 EcE24377A_0478 Escherichia coli E24377A competence protein ComEA YP_001461629.1 499085 D 331111 CDS YP_001461630.1 157156010 5590683 499550..499948 1 NC_009801.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051; thioesterase 499948 5590683 EcE24377A_0479 Escherichia coli E24377A thioesterase YP_001461630.1 499550 D 331111 CDS YP_001461631.1 157156536 5587100 complement(500000..500695) 1 NC_009801.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 500695 queC 5587100 queC Escherichia coli E24377A queuosine biosynthesis protein QueC YP_001461631.1 500000 R 331111 CDS YP_001461632.1 157155849 5586781 complement(500760..502460) 1 NC_009801.1 identified by match to protein family HMM PF00496; solute-binding family 5 protein 502460 5586781 EcE24377A_0481 Escherichia coli E24377A solute-binding family 5 protein YP_001461632.1 500760 R 331111 CDS YP_001461633.1 157156257 5590290 502560..503378 1 NC_009801.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; hydrolase Cof 503378 cof 5590290 cof Escherichia coli E24377A hydrolase Cof YP_001461633.1 502560 D 331111 CDS YP_001461634.1 157159291 5590438 503531..503989 1 NC_009801.1 identified by match to protein family HMM PF01037; AsnC family transcriptional regulator 503989 5590438 EcE24377A_0483 Escherichia coli E24377A AsnC family transcriptional regulator YP_001461634.1 503531 D 331111 CDS YP_001461635.1 157154903 5588826 504019..505791 1 NC_009801.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; multidrug transporter membrane\ATP-binding components 505791 mdlA 5588826 mdlA Escherichia coli E24377A multidrug transporter membrane\ATP-binding components YP_001461635.1 504019 D 331111 CDS YP_001461636.1 157157939 5590331 505784..507565 1 NC_009801.1 identified by similarity to SP:P0AAG5; match to protein family HMM PF00005; match to protein family HMM PF00664; multidrug transporter membrane\ATP-binding components 507565 mdlB 5590331 mdlB Escherichia coli E24377A multidrug transporter membrane\ATP-binding components YP_001461636.1 505784 D 331111 CDS YP_001461637.1 157158324 5587971 507746..508084 1 NC_009801.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 508084 glnK 5587971 glnK Escherichia coli E24377A nitrogen regulatory protein P-II 2 YP_001461637.1 507746 D 331111 CDS YP_001461638.1 157157708 5588328 508114..509400 1 NC_009801.1 identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836; ammonium transporter 509400 amt 5588328 amt Escherichia coli E24377A ammonium transporter YP_001461638.1 508114 D 331111 CDS YP_001461639.1 157158552 5590692 complement(509448..510308) 1 NC_009801.1 identified by match to protein family HMM PF02551; match to protein family HMM TIGR00189; acyl-CoA thioesterase 510308 tesB 5590692 tesB Escherichia coli E24377A acyl-CoA thioesterase YP_001461639.1 509448 R 331111 CDS YP_001461640.1 157157879 5589457 510526..511098 1 NC_009801.1 lipoprotein 511098 5589457 EcE24377A_0489 Escherichia coli E24377A lipoprotein YP_001461640.1 510526 D 331111 CDS YP_001461641.1 157157382 5588406 complement(511129..511518) 1 NC_009801.1 identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589; methylated-DNA-[protein]-cysteine S-methyltransferase 511518 5588406 EcE24377A_0490 Escherichia coli E24377A methylated-DNA-[protein]-cysteine S-methyltransferase YP_001461641.1 511129 R 331111 CDS YP_001461642.1 157158965 5590148 511819..512172 1 NC_009801.1 identified by match to protein family HMM PF07237; hypothetical protein 512172 5590148 EcE24377A_0491 Escherichia coli E24377A hypothetical protein YP_001461642.1 511819 D 331111 CDS YP_001461643.1 157158408 5589942 complement(512214..513770) 1 NC_009801.1 identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase domain-containing protein 513770 5589942 EcE24377A_0492 Escherichia coli E24377A cyclic diguanylate phosphodiesterase domain-containing protein YP_001461643.1 512214 R 331111 CDS YP_001461644.1 157156260 5588935 complement(513928..514437) 1 NC_009801.1 hypothetical protein 514437 5588935 EcE24377A_0493 Escherichia coli E24377A hypothetical protein YP_001461644.1 513928 R 331111 CDS YP_001461645.1 157155912 5590241 complement(514514..515065) 1 NC_009801.1 identified by similarity to SP:P77791; match to protein family HMM PF00132; maltose O-acetyltransferase 515065 maa 5590241 maa Escherichia coli E24377A maltose O-acetyltransferase YP_001461645.1 514514 R 331111 CDS YP_001461646.1 157157278 5586972 complement(515481..515855) 1 NC_009801.1 identified by similarity to GB:ABB65073.1; hypothetical protein 515855 5586972 EcE24377A_0495 Escherichia coli E24377A hypothetical protein YP_001461646.1 515481 R 331111 CDS YP_001461647.1 157156955 5588984 complement(516401..519550) 1 NC_009801.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; acriflavine resistance protein B 519550 5588984 EcE24377A_0496 Escherichia coli E24377A acriflavine resistance protein B YP_001461647.1 516401 R 331111 CDS YP_001461648.1 157157374 5587606 complement(519573..520766) 1 NC_009801.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; acriflavine resistance protein A 520766 acrA 5587606 acrA Escherichia coli E24377A acriflavine resistance protein A YP_001461648.1 519573 R 331111 CDS YP_001461649.1 157156905 5586126 520908..521555 1 NC_009801.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 521555 acrR 5586126 acrR Escherichia coli E24377A DNA-binding transcriptional repressor AcrR YP_001461649.1 520908 D 331111 CDS YP_001461650.1 157157065 5590251 521637..521801 1 NC_009801.1 identified by glimmer; hypothetical protein 521801 5590251 EcE24377A_0499 Escherichia coli E24377A hypothetical protein YP_001461650.1 521637 D 331111 CDS YP_001461651.1 157156171 5588359 521683..525045 1 NC_009801.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 525045 kefA 5588359 kefA Escherichia coli E24377A potassium efflux protein KefA YP_001461651.1 521683 D 331111 CDS YP_001461652.1 157157724 5590787 525091..525240 1 NC_009801.1 identified by glimmer; hypothetical protein 525240 5590787 EcE24377A_0501 Escherichia coli E24377A hypothetical protein YP_001461652.1 525091 D 331111 CDS YP_001461653.1 157158044 5589395 complement(525257..525418) 1 NC_009801.1 identified by similarity to RF:NP_455077.1; hypothetical protein 525418 5589395 EcE24377A_0502 Escherichia coli E24377A hypothetical protein YP_001461653.1 525257 R 331111 CDS YP_001461654.1 157157537 5589648 complement(525432..525959) 1 NC_009801.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' 525959 priC 5589648 priC Escherichia coli E24377A primosomal replication protein N'' YP_001461654.1 525432 R 331111 CDS YP_001461655.1 157159378 5587907 526029..526406 1 NC_009801.1 identified by match to protein family HMM PF04304; hypothetical protein 526406 5587907 EcE24377A_0504 Escherichia coli E24377A hypothetical protein YP_001461655.1 526029 D 331111 CDS YP_001461656.1 157158833 5587881 526381..526491 1 NC_009801.1 identified by glimmer; hypothetical protein 526491 5587881 EcE24377A_0505 Escherichia coli E24377A hypothetical protein YP_001461656.1 526381 D 331111 CDS YP_001461657.1 157155373 5586321 526559..527110 1 NC_009801.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 527110 apt 5586321 apt Escherichia coli E24377A adenine phosphoribosyltransferase YP_001461657.1 526559 D 331111 CDS YP_001461658.1 157154853 5590530 527239..529170 1 NC_009801.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 529170 dnaX 5590530 dnaX Escherichia coli E24377A DNA polymerase III subunits gamma and tau YP_001461658.1 527239 D 331111 CDS YP_001461659.1 157155769 5589069 complement(529199..529576) 1 NC_009801.1 identified by glimmer; hypothetical protein 529576 5589069 EcE24377A_0508 Escherichia coli E24377A hypothetical protein YP_001461659.1 529199 R 331111 CDS YP_001461660.1 157158940 5586516 529223..529552 1 NC_009801.1 identified by similarity to GB:AAZ90762.1; match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein 529552 5586516 EcE24377A_0509 Escherichia coli E24377A hypothetical protein YP_001461660.1 529223 D 331111 CDS YP_001461661.1 157157829 5588187 529552..530157 1 NC_009801.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 530157 recR 5588187 recR Escherichia coli E24377A recombination protein RecR YP_001461661.1 529552 D 331111 CDS YP_001461662.1 157155982 5586877 530267..532141 1 NC_009801.1 molecular chaperone; heat shock protein 90 532141 htpG 5586877 htpG Escherichia coli E24377A heat shock protein 90 YP_001461662.1 530267 D 331111 CDS YP_001461663.1 157154899 5586762 532322..532966 1 NC_009801.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 532966 adk 5586762 adk Escherichia coli E24377A adenylate kinase YP_001461663.1 532322 D 331111 CDS YP_001461664.1 157158688 5586173 533202..534164 1 NC_009801.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 534164 hemH 5586173 hemH Escherichia coli E24377A ferrochelatase YP_001461664.1 533202 D 331111 CDS YP_001461665.1 157159249 5590414 complement(534161..535120) 1 NC_009801.1 identified by similarity to SP:P23872; match to protein family HMM PF07859; acetyl esterase 535120 aes 5590414 aes Escherichia coli E24377A acetyl esterase YP_001461665.1 534161 R 331111 CDS YP_001461666.1 157157660 5590882 535272..536576 1 NC_009801.1 identified by similarity to SP:P0AEW6; match to protein family HMM PF00294; inosine-guanosine kinase 536576 gsk 5590882 gsk Escherichia coli E24377A inosine-guanosine kinase YP_001461666.1 535272 D 331111 CDS YP_001461667.1 157158216 5590080 complement(536709..538385) 1 NC_009801.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein 538385 5590080 EcE24377A_0517 Escherichia coli E24377A cation:proton antiport protein YP_001461667.1 536709 R 331111 CDS YP_001461668.1 157158710 5587835 complement(538623..539843) 1 NC_009801.1 identified by match to protein family HMM PF07690; fosmidomycin resistance protein 539843 fsr 5587835 fsr Escherichia coli E24377A fosmidomycin resistance protein YP_001461668.1 538623 R 331111 CDS YP_001461669.1 157157603 5589976 540061..541713 1 NC_009801.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 541713 ushA 5589976 ushA Escherichia coli E24377A bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic YP_001461669.1 540061 D 331111 CDS YP_001461670.1 157158258 5586983 complement(541750..542229) 1 NC_009801.1 identified by match to protein family HMM PF04073; match to protein family HMM TIGR00011; hypothetical protein 542229 5586983 EcE24377A_0520 Escherichia coli E24377A hypothetical protein YP_001461670.1 541750 R 331111 CDS YP_001461671.1 157158629 5589609 complement(542433..543227) 1 NC_009801.1 identified by match to protein family HMM PF07446; GumN family protein 543227 5589609 EcE24377A_0521 Escherichia coli E24377A GumN family protein YP_001461671.1 542433 R 331111 CDS YP_001461672.1 157159330 5586154 543311..543706 1 NC_009801.1 identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607; addiction module antidote protein 543706 5586154 EcE24377A_0522 Escherichia coli E24377A addiction module antidote protein YP_001461672.1 543311 D 331111 CDS YP_001461673.1 157155513 5590560 complement(543820..546324) 1 NC_009801.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; copper exporting ATPase 546324 copA 5590560 copA Escherichia coli E24377A copper exporting ATPase YP_001461673.1 543820 R 331111 CDS YP_001461674.1 157156184 5587038 546586..547518 1 NC_009801.1 catalyzes the formation of glutamate from glutamine; glutaminase 547518 glsA1 5587038 glsA1 Escherichia coli E24377A glutaminase YP_001461674.1 546586 D 331111 CDS YP_001461675.1 157156643 5589271 547521..548813 1 NC_009801.1 identified by match to protein family HMM PF00324; match to protein family HMM PF01490; match to protein family HMM PF03845; amino acid permease 548813 5589271 EcE24377A_0525 Escherichia coli E24377A amino acid permease YP_001461675.1 547521 D 331111 CDS YP_001461676.1 157157213 5587899 548938..549345 1 NC_009801.1 activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 549345 cueR 5587899 cueR Escherichia coli E24377A DNA-binding transcriptional regulator CueR YP_001461676.1 548938 D 331111 CDS YP_001461677.1 157158261 5586387 complement(549346..549804) 1 NC_009801.1 identified by match to protein family HMM PF01957; nodulation efficiency family protein 549804 5586387 EcE24377A_0527 Escherichia coli E24377A nodulation efficiency family protein YP_001461677.1 549346 R 331111 CDS YP_001461678.1 157155972 5588911 complement(549801..550718) 1 NC_009801.1 identified by match to protein family HMM PF01145; hypothetical protein 550718 5588911 EcE24377A_0528 Escherichia coli E24377A hypothetical protein YP_001461678.1 549801 R 331111 CDS YP_001461679.1 157156724 5589651 550864..551541 1 NC_009801.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 551541 5589651 EcE24377A_0529 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001461679.1 550864 D 331111 CDS YP_001461680.1 157155957 5586244 551528..552307 1 NC_009801.1 identified by match to protein family HMM PF03649; match to protein family HMM TIGR00245; hypothetical protein 552307 5586244 EcE24377A_0530 Escherichia coli E24377A hypothetical protein YP_001461680.1 551528 D 331111 CDS YP_001461681.1 157156452 5587129 complement(552370..553224) 1 NC_009801.1 identified by similarity to SP:P77395; match to protein family HMM PF00085; protein YbbN 553224 ybbN 5587129 ybbN Escherichia coli E24377A protein YbbN YP_001461681.1 552370 R 331111 CDS YP_001461682.1 157155767 5588268 complement(553285..554094) 1 NC_009801.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659; short chain dehydrogenase 554094 5588268 EcE24377A_0532 Escherichia coli E24377A short chain dehydrogenase YP_001461682.1 553285 R 331111 CDS YP_001461683.1 157155032 5587668 complement(554084..554740) 1 NC_009801.1 identified by similarity to SP:P0ADA1; match to protein family HMM PF00657; multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 554740 tesA 5587668 tesA Escherichia coli E24377A multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 YP_001461683.1 554084 R 331111 CDS YP_001461684.1 157159113 5589487 554678..555364 1 NC_009801.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 555364 5589487 EcE24377A_0534 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001461684.1 554678 D 331111 CDS YP_001461685.1 157158498 5588740 555361..557775 1 NC_009801.1 identified by match to protein family HMM PF02687; ABC transporter permease 557775 5588740 EcE24377A_0535 Escherichia coli E24377A ABC transporter permease YP_001461685.1 555361 D 331111 CDS YP_001461686.1 157157827 5588669 558205..562494 1 NC_009801.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; RhsD protein 562494 5588669 EcE24377A_0536 Escherichia coli E24377A RhsD protein YP_001461686.1 558205 D 331111 CDS YP_001461687.1 157157139 5589856 562534..562902 1 NC_009801.1 lipoprotein 562902 5589856 EcE24377A_0537 Escherichia coli E24377A lipoprotein YP_001461687.1 562534 D 331111 CDS YP_001461688.1 157158632 5589771 562902..563612 1 NC_009801.1 identified by match to protein family HMM PF03527; Rhs domain-containing protein 563612 5589771 EcE24377A_0538 Escherichia coli E24377A Rhs domain-containing protein YP_001461688.1 562902 D 331111 CDS YP_001461689.1 157156550 5588169 complement(565087..566181) 1 NC_009801.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase 566181 selU 5588169 selU Escherichia coli E24377A tRNA 2-selenouridine synthase YP_001461689.1 565087 R 331111 CDS YP_001461690.1 157156027 5586407 complement(566250..567176) 1 NC_009801.1 activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS 567176 5586407 EcE24377A_0541 Escherichia coli E24377A DNA-binding transcriptional activator AllS YP_001461690.1 566250 R 331111 CDS YP_001461691.1 157155464 5586554 567406..567888 1 NC_009801.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 567888 allA 5586554 allA Escherichia coli E24377A ureidoglycolate hydrolase YP_001461691.1 567406 D 331111 CDS YP_001461692.1 157154938 5587443 567966..568781 1 NC_009801.1 regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 568781 allR 5587443 allR Escherichia coli E24377A DNA-binding transcriptional repressor AllR YP_001461692.1 567966 D 331111 CDS YP_001461693.1 157158653 5586740 568871..570652 1 NC_009801.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 570652 gcl 5586740 gcl Escherichia coli E24377A glyoxylate carboligase YP_001461693.1 568871 D 331111 CDS YP_001461694.1 157158233 5589178 570665..571441 1 NC_009801.1 identified by match to protein family HMM PF01261; match to protein family HMM TIGR03234; hydroxypyruvate isomerase 571441 hyi 5589178 hyi Escherichia coli E24377A hydroxypyruvate isomerase YP_001461694.1 570665 D 331111 CDS YP_001461695.1 157157577 5587211 571541..572419 1 NC_009801.1 identified by match to protein family HMM PF03446; match to protein family HMM TIGR01505; 2-hydroxy-3-oxopropionate reductase 572419 5587211 EcE24377A_0546 Escherichia coli E24377A 2-hydroxy-3-oxopropionate reductase YP_001461695.1 571541 D 331111 CDS YP_001461696.1 157156624 5587684 572588..574042 1 NC_009801.1 identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800; allantoin permease 574042 5587684 EcE24377A_0547 Escherichia coli E24377A allantoin permease YP_001461696.1 572588 D 331111 CDS YP_001461697.1 157155927 5586304 574102..575463 1 NC_009801.1 Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 575463 allB 5586304 allB Escherichia coli E24377A allantoinase YP_001461697.1 574102 D 331111 CDS YP_001461698.1 157157735 5589898 575520..576821 1 NC_009801.1 identified by match to protein family HMM PF00860; purine permease YbbY 576821 5589898 EcE24377A_0550 Escherichia coli E24377A purine permease YbbY YP_001461698.1 575520 D 331111 CDS YP_001461699.1 157158280 5590836 complement(576482..576574) 1 NC_009801.1 identified by glimmer; hypothetical protein 576574 5590836 EcE24377A_0549 Escherichia coli E24377A hypothetical protein YP_001461699.1 576482 R 331111 CDS YP_001461700.1 157156007 5589286 576843..577988 1 NC_009801.1 identified by similarity to SP:P77364; match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase 577988 5589286 EcE24377A_0551 Escherichia coli E24377A glycerate kinase YP_001461700.1 576843 D 331111 CDS YP_001461701.1 157156401 5586772 578047..578187 1 NC_009801.1 identified by glimmer; hypothetical protein 578187 5586772 EcE24377A_0552 Escherichia coli E24377A hypothetical protein YP_001461701.1 578047 D 331111 CDS YP_001461702.1 157157046 5589533 complement(578216..579001) 1 NC_009801.1 identified by match to protein family HMM PF05899; match to protein family HMM PF07883; match to protein family HMM TIGR03214; hypothetical protein 579001 5589533 EcE24377A_0553 Escherichia coli E24377A hypothetical protein YP_001461702.1 578216 R 331111 CDS YP_001461703.1 157155718 5588409 complement(579012..580247) 1 NC_009801.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 580247 allC 5588409 allC Escherichia coli E24377A allantoate amidohydrolase YP_001461703.1 579012 R 331111 CDS YP_001461704.1 157158586 5588039 complement(580269..581318) 1 NC_009801.1 identified by similarity to SP:P77555; match to protein family HMM PF02615; match to protein family HMM TIGR03175; ureidoglycolate dehydrogenase 581318 allD 5588039 allD Escherichia coli E24377A ureidoglycolate dehydrogenase YP_001461704.1 580269 R 331111 CDS YP_001461705.1 157159355 5586054 581635..583302 1 NC_009801.1 multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 583302 5586054 EcE24377A_0556 Escherichia coli E24377A membrane protein FdrA YP_001461705.1 581635 D 331111 CDS YP_001461706.1 157157509 5590681 583312..584571 1 NC_009801.1 identified by match to protein family HMM PF06545; hypothetical protein 584571 5590681 EcE24377A_0557 Escherichia coli E24377A hypothetical protein YP_001461706.1 583312 D 331111 CDS YP_001461707.1 157156050 5588564 584582..585397 1 NC_009801.1 ylbF; identified by similarity to GB:ABB65130.1; hypothetical protein 585397 5588564 EcE24377A_0558 Escherichia coli E24377A hypothetical protein YP_001461707.1 584582 D 331111 CDS YP_001461708.1 157159246 5588659 585394..586287 1 NC_009801.1 identified by match to protein family HMM PF00696; match to protein family HMM TIGR00746; carbamate kinase 586287 arcC 5588659 arcC Escherichia coli E24377A carbamate kinase YP_001461708.1 585394 D 331111 CDS YP_001461709.1 157158441 5586456 586324..586431 1 NC_009801.1 identified by glimmer; hypothetical protein 586431 5586456 EcE24377A_0561 Escherichia coli E24377A hypothetical protein YP_001461709.1 586324 D 331111 CDS YP_001461710.1 157158959 5588396 complement(586424..587491) 1 NC_009801.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 587491 purK 5588396 purK Escherichia coli E24377A phosphoribosylaminoimidazole carboxylase ATPase subunit YP_001461710.1 586424 R 331111 CDS YP_001461711.1 157157867 5585948 complement(587488..587997) 1 NC_009801.1 identified by similarity to SP:P0AG18; match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase catalytic subunit 587997 purE 5585948 purE Escherichia coli E24377A phosphoribosylaminoimidazole carboxylase catalytic subunit YP_001461711.1 587488 R 331111 CDS YP_001461712.1 157157360 5589752 complement(588115..588837) 1 NC_009801.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 588837 lpxH 5589752 lpxH Escherichia coli E24377A UDP-2,3-diacylglucosamine hydrolase YP_001461712.1 588115 R 331111 CDS YP_001461713.1 157154955 5586737 complement(588840..589334) 1 NC_009801.1 identified by similarity to SP:P23869; match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase B 589334 ppiB 5586737 ppiB Escherichia coli E24377A peptidyl-prolyl cis-trans isomerase B YP_001461713.1 588840 R 331111 CDS YP_001461714.1 157155754 5586047 589508..590893 1 NC_009801.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 590893 cysS 5586047 cysS Escherichia coli E24377A cysteinyl-tRNA synthetase YP_001461714.1 589508 D 331111 CDS YP_001461715.1 157155142 5589953 complement(590929..591450) 1 NC_009801.1 identified by match to protein family HMM PF04307; hypothetical protein 591450 5589953 EcE24377A_0567 Escherichia coli E24377A hypothetical protein YP_001461715.1 590929 R 331111 CDS YP_001461716.1 157158070 5590498 complement(591558..591770) 1 NC_009801.1 identified by similarity to SP:P0AAS8; hypothetical protein 591770 5590498 EcE24377A_0569 Escherichia coli E24377A hypothetical protein YP_001461716.1 591558 R 331111 CDS YP_001461717.1 157156074 5590848 complement(591772..592638) 1 NC_009801.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 592638 folD 5590848 folD Escherichia coli E24377A bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_001461717.1 591772 R 331111 CDS YP_001461718.1 157156301 5588457 593119..593661 1 NC_009801.1 identified by similarity to SP:P04128; match to protein family HMM PF00419; type-1 fimbrial protein 593661 5588457 EcE24377A_0571 Escherichia coli E24377A type-1 fimbrial protein YP_001461718.1 593119 D 331111 CDS YP_001461719.1 157159320 5588775 593757..593891 1 NC_009801.1 identified by glimmer; hypothetical protein 593891 5588775 EcE24377A_0572 Escherichia coli E24377A hypothetical protein YP_001461719.1 593757 D 331111 CDS YP_001461720.1 157157610 5589312 593881..594573 1 NC_009801.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; chaperone protein FimC 594573 fimC 5589312 fimC Escherichia coli E24377A chaperone protein FimC YP_001461720.1 593881 D 331111 CDS YP_001461721.1 157154807 5588653 597067..597228 1 NC_009801.1 identified by glimmer; hypothetical protein 597228 5588653 EcE24377A_0575 Escherichia coli E24377A hypothetical protein YP_001461721.1 597067 D 331111 CDS YP_001461722.1 157157870 5587202 597225..598232 1 NC_009801.1 identified by similarity to GB:AAD17914.1; mannose binding protein FimH 598232 5587202 EcE24377A_0576 Escherichia coli E24377A mannose binding protein FimH YP_001461722.1 597225 D 331111 CDS YP_001461723.1 157157441 5588691 complement(598761..599393) 1 NC_009801.1 activates the production of the major fimbrae protein FimA; transcriptional regulator FimZ 599393 fimZ 5588691 fimZ Escherichia coli E24377A transcriptional regulator FimZ YP_001461723.1 598761 R 331111 CDS YP_001461724.1 157155321 5586546 complement(599758..600519) 1 NC_009801.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 600519 5586546 EcE24377A_0579 Escherichia coli E24377A AraC family transcriptional regulator YP_001461724.1 599758 R 331111 CDS YP_001461725.1 157154840 5590674 complement(600702..601592) 1 NC_009801.1 hypothetical protein 601592 5590674 EcE24377A_0580 Escherichia coli E24377A hypothetical protein YP_001461725.1 600702 R 331111 CDS YP_001461726.1 157159367 5589025 complement(601593..604565) 1 NC_009801.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; bacteriophage N4 receptor, outer membrane subunit 604565 5589025 EcE24377A_0581 Escherichia coli E24377A bacteriophage N4 receptor, outer membrane subunit YP_001461726.1 601593 R 331111 CDS YP_001461727.1 157156705 5586798 complement(607057..608193) 1 NC_009801.1 identified by match to protein family HMM PF01609; ISEc3, transposase 608193 5586798 EcE24377A_0583 Escherichia coli E24377A ISEc3, transposase YP_001461727.1 607057 R 331111 CDS YP_001461728.1 157156167 5588792 complement(608297..608608) 1 NC_009801.1 identified by glimmer; hypothetical protein 608608 5588792 EcE24377A_0584 Escherichia coli E24377A hypothetical protein YP_001461728.1 608297 R 331111 CDS YP_001461729.1 157158186 5589845 complement(608971..613773) 1 NC_009801.1 identified by match to protein family HMM PF05488; match to protein family HMM PF05593; match to protein family HMM TIGR01643; hypothetical protein 613773 5589845 EcE24377A_0585 Escherichia coli E24377A hypothetical protein YP_001461729.1 608971 R 331111 CDS YP_001461730.1 157157295 5586463 complement(613853..614314) 1 NC_009801.1 identified by similarity to GB:CAE12649.1; match to protein family HMM PF08786; hypothetical protein 614314 5586463 EcE24377A_0586 Escherichia coli E24377A hypothetical protein YP_001461730.1 613853 R 331111 CDS YP_001461731.1 157155367 5586910 complement(614342..616243) 1 NC_009801.1 identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361; ImpA family type VI secretion-associated protein 616243 5586910 EcE24377A_0587 Escherichia coli E24377A ImpA family type VI secretion-associated protein YP_001461731.1 614342 R 331111 CDS YP_001461732.1 157154804 5589793 complement(616980..618428) 1 NC_009801.1 identified by similarity to SP:P77485; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386; sensor kinase CusS 618428 cusS 5589793 cusS Escherichia coli E24377A sensor kinase CusS YP_001461732.1 616980 R 331111 CDS YP_001461733.1 157156750 5587710 complement(618418..619101) 1 NC_009801.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 619101 cusR 5587710 cusR Escherichia coli E24377A DNA-binding transcriptional activator CusR YP_001461733.1 618418 R 331111 CDS YP_001461734.1 157156221 5585994 619258..620640 1 NC_009801.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 620640 cusC 5585994 cusC Escherichia coli E24377A copper/silver efflux system outer membrane protein CusC YP_001461734.1 619258 D 331111 CDS YP_001461735.1 157158017 5587231 620664..620996 1 NC_009801.1 copper-binding protein 620996 cusF 5587231 cusF Escherichia coli E24377A copper-binding protein YP_001461735.1 620664 D 331111 CDS YP_001461736.1 157156749 5589561 621012..622235 1 NC_009801.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 622235 cusB 5589561 cusB Escherichia coli E24377A copper/silver efflux system membrane fusion protein CusB YP_001461736.1 621012 D 331111 CDS YP_001461737.1 157159358 5589711 622247..625390 1 NC_009801.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00914; cation efflux system protein cusA 625390 cusA 5589711 cusA Escherichia coli E24377A cation efflux system protein cusA YP_001461737.1 622247 D 331111 CDS YP_001461738.1 157158824 5590654 625492..626868 1 NC_009801.1 identified by match to protein family HMM PF00324; phenylalanine transporter 626868 pheP 5590654 pheP Escherichia coli E24377A phenylalanine transporter YP_001461738.1 625492 D 331111 CDS YP_001461739.1 157158754 5587449 complement(626936..628183) 1 NC_009801.1 identified by match to protein family HMM PF00924; small conductance mechanosensitive ion channel (MscS) family protein 628183 ybdG 5587449 ybdG Escherichia coli E24377A small conductance mechanosensitive ion channel (MscS) family protein YP_001461739.1 626936 R 331111 CDS YP_001461740.1 157155958 5588626 complement(628291..628944) 1 NC_009801.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 628944 nfnB 5588626 nfnB Escherichia coli E24377A dihydropteridine reductase YP_001461740.1 628291 R 331111 CDS YP_001461741.1 157158195 5586577 complement(628992..629084) 1 NC_009801.1 identified by glimmer; hypothetical protein 629084 5586577 EcE24377A_0597 Escherichia coli E24377A hypothetical protein YP_001461741.1 628992 R 331111 CDS YP_001461742.1 157155661 5586825 complement(629038..629406) 1 NC_009801.1 identified by similarity to GB:BAA35219.1; match to protein family HMM PF04237; hypothetical protein 629406 5586825 EcE24377A_0598 Escherichia coli E24377A hypothetical protein YP_001461742.1 629038 R 331111 CDS YP_001461743.1 157155572 5587827 complement(629471..629719) 1 NC_009801.1 identified by match to protein family HMM PF06643; lipoprotein 629719 5587827 EcE24377A_0599 Escherichia coli E24377A lipoprotein YP_001461743.1 629471 R 331111 CDS YP_001461744.1 157157519 5589382 complement(629785..630903) 1 NC_009801.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 630903 5589382 EcE24377A_0600 Escherichia coli E24377A carboxylate-amine ligase YP_001461744.1 629785 R 331111 CDS YP_001461745.1 157159397 5589703 complement(632133..632762) 1 NC_009801.1 identified by similarity to SP:P19925; match to protein family HMM PF01648; phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex 632762 entD 5589703 entD Escherichia coli E24377A phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex YP_001461745.1 632133 R 331111 CDS YP_001461746.1 157157247 5587372 complement(632928..635168) 1 NC_009801.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 635168 fepA 5587372 fepA Escherichia coli E24377A outer membrane receptor FepA YP_001461746.1 632928 R 331111 CDS YP_001461747.1 157157006 5590648 635489..636613 1 NC_009801.1 identified by similarity to SP:P13039; match to protein family HMM PF00756; enterobactin/ferric enterobactin esterase 636613 fes 5590648 fes Escherichia coli E24377A enterobactin/ferric enterobactin esterase YP_001461747.1 635489 D 331111 CDS YP_001461748.1 157156480 5586323 636616..636834 1 NC_009801.1 identified by match to protein family HMM PF03621; mbtH-like protein 636834 5586323 EcE24377A_0605 Escherichia coli E24377A mbtH-like protein YP_001461748.1 636616 D 331111 CDS YP_001461749.1 157155493 5589658 636831..640712 1 NC_009801.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 640712 entF 5589658 entF Escherichia coli E24377A enterobactin synthase subunit F YP_001461749.1 636831 D 331111 CDS YP_001461750.1 157154811 5586632 640928..642061 1 NC_009801.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 642061 fepE 5586632 fepE Escherichia coli E24377A ferric enterobactin transport protein FepE YP_001461750.1 640928 D 331111 CDS YP_001461751.1 157158899 5587697 complement(642058..642873) 1 NC_009801.1 with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein 642873 fepC 5587697 fepC Escherichia coli E24377A iron-enterobactin transporter ATP-binding protein YP_001461751.1 642058 R 331111 CDS YP_001461752.1 157158363 5585928 complement(642870..643862) 1 NC_009801.1 with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease 643862 fepG 5585928 fepG Escherichia coli E24377A iron-enterobactin transporter permease YP_001461752.1 642870 R 331111 CDS YP_001461753.1 157157850 5587284 complement(643859..644863) 1 NC_009801.1 with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein 644863 fepD 5587284 fepD Escherichia coli E24377A iron-enterobactin transporter membrane protein YP_001461753.1 643859 R 331111 CDS YP_001461754.1 157157391 5585992 644974..646224 1 NC_009801.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 646224 5585992 EcE24377A_0611 Escherichia coli E24377A enterobactin exporter EntS YP_001461754.1 644974 D 331111 CDS YP_001461755.1 157155104 5590746 complement(646228..647184) 1 NC_009801.1 with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 647184 fepB 5590746 fepB Escherichia coli E24377A iron-enterobactin transporter periplasmic binding protein YP_001461755.1 646228 R 331111 CDS YP_001461756.1 157157000 5588176 647559..648734 1 NC_009801.1 identified by similarity to SP:P0AEJ2; match to protein family HMM PF00425; match to protein family HMM TIGR00543; isochorismate synthase 648734 entC 5588176 entC Escherichia coli E24377A isochorismate synthase YP_001461756.1 647559 D 331111 CDS YP_001461757.1 157158923 5586822 648744..650354 1 NC_009801.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 650354 entE 5586822 entE Escherichia coli E24377A enterobactin synthase subunit E YP_001461757.1 648744 D 331111 CDS YP_001461758.1 157158440 5588941 650368..651225 1 NC_009801.1 identified by similarity to SP:P0ADI4; match to protein family HMM PF00550; match to protein family HMM PF00857; isochorismatase 651225 entB 5588941 entB Escherichia coli E24377A isochorismatase YP_001461758.1 650368 D 331111 CDS YP_001461759.1 157155841 5588316 651225..651971 1 NC_009801.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 651971 entA 5588316 entA Escherichia coli E24377A 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_001461759.1 651225 D 331111 CDS YP_001461760.1 157158746 5588952 651974..652387 1 NC_009801.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 652387 5588952 EcE24377A_0617 Escherichia coli E24377A hypothetical protein YP_001461760.1 651974 D 331111 CDS YP_001461761.1 157155305 5589484 652568..654673 1 NC_009801.1 identified by similarity to SP:P15078; match to protein family HMM PF02554; carbon starvation protein A 654673 cstA 5589484 cstA Escherichia coli E24377A carbon starvation protein A YP_001461761.1 652568 D 331111 CDS YP_001461762.1 157155692 5586589 654855..655052 1 NC_009801.1 identified by similarity to SP:P0AAT1; match to protein family HMM PF04328; hypothetical protein 655052 5586589 EcE24377A_0619 Escherichia coli E24377A hypothetical protein YP_001461762.1 654855 D 331111 CDS YP_001461763.1 157156258 5590508 complement(655062..656150) 1 NC_009801.1 member of the iron-containing alcohol dehydrogenase; unknown function; hypothetical protein 656150 5590508 EcE24377A_0620 Escherichia coli E24377A hypothetical protein YP_001461763.1 655062 R 331111 CDS YP_001461764.1 157156761 5590439 656259..657419 1 NC_009801.1 catalyzes the transfer of an amino moiety; aminotransferase 657419 5590439 EcE24377A_0621 Escherichia coli E24377A aminotransferase YP_001461764.1 656259 D 331111 CDS YP_001461765.1 157158924 5589247 complement(657420..658037) 1 NC_009801.1 identified by match to protein family HMM PF02195; IbrB protein 658037 5589247 EcE24377A_0622 Escherichia coli E24377A IbrB protein YP_001461765.1 657420 R 331111 CDS YP_001461766.1 157157258 5586050 complement(658022..659242) 1 NC_009801.1 identified by match to protein family HMM PF01507; IbrA protein 659242 5586050 EcE24377A_0623 Escherichia coli E24377A IbrA protein YP_001461766.1 658022 R 331111 CDS YP_001461767.1 157155161 5589398 complement(659389..660291) 1 NC_009801.1 identified by match to protein family HMM PF00126; LysR family transcriptional regulator 660291 5589398 EcE24377A_0624 Escherichia coli E24377A LysR family transcriptional regulator YP_001461767.1 659389 R 331111 CDS YP_001461768.1 157155921 5586095 complement(660500..661246) 1 NC_009801.1 Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase 661246 dsbG 5586095 dsbG Escherichia coli E24377A disulfide isomerase/thiol-disulfide oxidase YP_001461768.1 660500 R 331111 CDS YP_001461769.1 157155096 5587391 661618..662181 1 NC_009801.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase 662181 ahpC 5587391 ahpC Escherichia coli E24377A alkyl hydroperoxide reductase YP_001461769.1 661618 D 331111 CDS YP_001461770.1 157158950 5588604 662396..663991 1 NC_009801.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR03140; alkyl hydroperoxide reductase 663991 ahpF 5588604 ahpF Escherichia coli E24377A alkyl hydroperoxide reductase YP_001461770.1 662396 D 331111 CDS YP_001461771.1 157154993 5587852 complement(664112..664540) 1 NC_009801.1 identified by similarity to SP:P39177; match to protein family HMM PF00582; universal stress protein G 664540 uspG 5587852 uspG Escherichia coli E24377A universal stress protein G YP_001461771.1 664112 R 331111 CDS YP_001461772.1 157157934 5589479 664472..664642 1 NC_009801.1 identified by glimmer; hypothetical protein 664642 5589479 EcE24377A_0629 Escherichia coli E24377A hypothetical protein YP_001461772.1 664472 D 331111 CDS YP_001461773.1 157158316 5588012 664761..665999 1 NC_009801.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; zinc-binding dehydrogenase oxidoreductase 665999 5588012 EcE24377A_0630 Escherichia coli E24377A zinc-binding dehydrogenase oxidoreductase YP_001461773.1 664761 D 331111 CDS YP_001461774.1 157157538 5588516 complement(666003..666131) 1 NC_009801.1 identified by glimmer; hypothetical protein 666131 5588516 EcE24377A_0631 Escherichia coli E24377A hypothetical protein YP_001461774.1 666003 R 331111 CDS YP_001461775.1 157157899 5587908 complement(666230..666640) 1 NC_009801.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 666640 rnk 5587908 rnk Escherichia coli E24377A nucleoside diphosphate kinase regulator YP_001461775.1 666230 R 331111 CDS YP_001461776.1 157157029 5586275 complement(666870..667676) 1 NC_009801.1 identified by similarity to SP:P21338; match to protein family HMM PF00445; ribonuclease I 667676 rna 5586275 rna Escherichia coli E24377A ribonuclease I YP_001461776.1 666870 R 331111 CDS YP_001461777.1 157155862 5589151 complement(667790..669253) 1 NC_009801.1 identified by similarity to SP:P0AE74; match to protein family HMM PF00939; match to protein family HMM TIGR00785; citrate transporter 669253 citT 5589151 citT Escherichia coli E24377A citrate transporter YP_001461777.1 667790 R 331111 CDS YP_001461778.1 157156539 5588447 complement(669304..670182) 1 NC_009801.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase 670182 citG 5588447 citG Escherichia coli E24377A triphosphoribosyl-dephospho-CoA synthase YP_001461778.1 669304 R 331111 CDS YP_001461779.1 157154930 5586612 complement(670157..670708) 1 NC_009801.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 670708 citX 5586612 citX Escherichia coli E24377A 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase YP_001461779.1 670157 R 331111 CDS YP_001461780.1 157156690 5587439 complement(670712..672244) 1 NC_009801.1 identified by match to protein family HMM PF04223; match to protein family HMM TIGR01584; citrate lyase subunit alpha 672244 citF 5587439 citF Escherichia coli E24377A citrate lyase subunit alpha YP_001461780.1 670712 R 331111 CDS YP_001461781.1 157158764 5586807 complement(672255..673163) 1 NC_009801.1 identified by match to protein family HMM PF03328; match to protein family HMM TIGR01588; citrate (pro-3S)-lyase subunit beta 673163 citE 5586807 citE Escherichia coli E24377A citrate (pro-3S)-lyase subunit beta YP_001461781.1 672255 R 331111 CDS YP_001461782.1 157155617 5589129 complement(673160..673456) 1 NC_009801.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 673456 citD 5589129 citD Escherichia coli E24377A citrate lyase subunit gamma YP_001461782.1 673160 R 331111 CDS YP_001461783.1 157157956 5588387 674452..674598 1 NC_009801.1 identified by glimmer; hypothetical protein 674598 5588387 EcE24377A_0641 Escherichia coli E24377A hypothetical protein YP_001461783.1 674452 D 331111 CDS YP_001461784.1 157157319 5589331 674908..676566 1 NC_009801.1 identified by similarity to SP:P77510; match to protein family HMM PF02518; sensor histidine kinase DpiB 676566 dpiB 5589331 dpiB Escherichia coli E24377A sensor histidine kinase DpiB YP_001461784.1 674908 D 331111 CDS YP_001461785.1 157156130 5588711 676535..677215 1 NC_009801.1 regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 677215 dpiA 5588711 dpiA Escherichia coli E24377A two-component response regulator DpiA YP_001461785.1 676535 D 331111 CDS YP_001461786.1 157155488 5586869 complement(677256..678641) 1 NC_009801.1 responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 678641 dcuC 5586869 dcuC Escherichia coli E24377A C4-dicarboxylate transporter DcuC YP_001461786.1 677256 R 331111 CDS YP_001461787.1 157157225 5588491 complement(678686..678796) 1 NC_009801.1 identified by glimmer; hypothetical protein 678796 5588491 EcE24377A_0645 Escherichia coli E24377A hypothetical protein YP_001461787.1 678686 R 331111 CDS YP_001461788.1 157156556 5586617 679000..679107 1 NC_009801.1 identified by glimmer; hypothetical protein 679107 5586617 EcE24377A_0646 Escherichia coli E24377A hypothetical protein YP_001461788.1 679000 D 331111 CDS YP_001461789.1 157158250 5586288 679230..679790 1 NC_009801.1 catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 679790 pagP 5586288 pagP Escherichia coli E24377A palmitoyl transferase YP_001461789.1 679230 D 331111 CDS YP_001461790.1 157157595 5587980 679965..680174 1 NC_009801.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 680174 cspE 5587980 cspE Escherichia coli E24377A cold shock protein CspE YP_001461790.1 679965 D 331111 CDS YP_001461791.1 157155816 5590216 complement(680228..680611) 1 NC_009801.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 680611 crcB 5590216 crcB Escherichia coli E24377A camphor resistance protein CrcB YP_001461791.1 680228 R 331111 CDS YP_001461792.1 157155257 5586278 680704..681492 1 NC_009801.1 identified by match to protein family HMM PF00795; carbon-nitrogen family hydrolase 681492 5586278 EcE24377A_0650 Escherichia coli E24377A carbon-nitrogen family hydrolase YP_001461792.1 680704 D 331111 CDS YP_001461793.1 157156847 5590662 681621..681824 1 NC_009801.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase E 681824 tatE 5590662 tatE Escherichia coli E24377A twin arginine translocase E YP_001461793.1 681621 D 331111 CDS YP_001461794.1 157156344 5587793 complement(681925..682890) 1 NC_009801.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 682890 lipA 5587793 lipA Escherichia coli E24377A lipoyl synthase YP_001461794.1 681925 R 331111 CDS YP_001461795.1 157156510 5586805 complement(682989..683102) 1 NC_009801.1 identified by glimmer; hypothetical protein 683102 5586805 EcE24377A_0653 Escherichia coli E24377A hypothetical protein YP_001461795.1 682989 R 331111 CDS YP_001461796.1 157154784 5590543 complement(683099..684052) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator 684052 5590543 EcE24377A_0654 Escherichia coli E24377A DNA-binding transcriptional regulator YP_001461796.1 683099 R 331111 CDS YP_001461797.1 157155500 5588748 complement(684312..684953) 1 NC_009801.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 684953 lipB 5588748 lipB Escherichia coli E24377A lipoate-protein ligase B YP_001461797.1 684312 R 331111 CDS YP_001461798.1 157158401 5586109 complement(685054..685317) 1 NC_009801.1 identified by similarity to SP:P0A8J4; match to protein family HMM PF04359; hypothetical protein 685317 5586109 EcE24377A_0656 Escherichia coli E24377A hypothetical protein YP_001461798.1 685054 R 331111 CDS YP_001461799.1 157159257 5586365 complement(685427..686638) 1 NC_009801.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase 686638 dacA 5586365 dacA Escherichia coli E24377A D-alanyl-D-alanine carboxypeptidase YP_001461799.1 685427 R 331111 CDS YP_001461800.1 157158169 5587045 686661..686801 1 NC_009801.1 hypothetical protein 686801 5587045 EcE24377A_0659 Escherichia coli E24377A hypothetical protein YP_001461800.1 686661 D 331111 CDS YP_001461801.1 157158068 5586476 complement(686778..687866) 1 NC_009801.1 identified by similarity to SP:P10100; match to protein family HMM PF03330; match to protein family HMM PF05036; match to protein family HMM TIGR00413; rare lipoprotein A 687866 rlpA 5586476 rlpA Escherichia coli E24377A rare lipoprotein A YP_001461801.1 686778 R 331111 CDS YP_001461802.1 157156312 5590846 complement(687877..688989) 1 NC_009801.1 identified by similarity to SP:P0ABG7; match to protein family HMM PF01098; match to protein family HMM TIGR02210; cell wall shape-determining protein 688989 mrdB 5590846 mrdB Escherichia coli E24377A cell wall shape-determining protein YP_001461802.1 687877 R 331111 CDS YP_001461803.1 157155963 5587497 complement(688992..690893) 1 NC_009801.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM TIGR03423; penicillin-binding protein 2 690893 mrdA 5587497 mrdA Escherichia coli E24377A penicillin-binding protein 2 YP_001461803.1 688992 R 331111 CDS YP_001461804.1 157155267 5589329 complement(690924..691391) 1 NC_009801.1 SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 691391 5589329 EcE24377A_0662 Escherichia coli E24377A rRNA large subunit methyltransferase YP_001461804.1 690924 R 331111 CDS YP_001461805.1 157157914 5587998 complement(691395..691712) 1 NC_009801.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090; hypothetical protein 691712 5587998 EcE24377A_0663 Escherichia coli E24377A hypothetical protein YP_001461805.1 691395 R 331111 CDS YP_001461806.1 157156202 5586346 complement(691972..692583) 1 NC_009801.1 identified by similarity to SP:P52086; match to protein family HMM PF00300; match to protein family HMM TIGR03162; alpha-ribazole-5'-phosphate phosphatase 692583 cobC 5586346 cobC Escherichia coli E24377A alpha-ribazole-5'-phosphate phosphatase YP_001461806.1 691972 R 331111 CDS YP_001461807.1 157154723 5588028 complement(692607..693248) 1 NC_009801.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 693248 nadD 5588028 nadD Escherichia coli E24377A nicotinic acid mononucleotide adenylyltransferase YP_001461807.1 692607 R 331111 CDS YP_001461808.1 157155534 5586759 complement(693250..694281) 1 NC_009801.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 694281 holA 5586759 holA Escherichia coli E24377A DNA polymerase III subunit delta YP_001461808.1 693250 R 331111 CDS YP_001461809.1 157158850 5589319 complement(694281..694862) 1 NC_009801.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 694862 5589319 EcE24377A_0667 Escherichia coli E24377A LPS-assembly lipoprotein RlpB YP_001461809.1 694281 R 331111 CDS YP_001461810.1 157158979 5586204 complement(694877..697459) 1 NC_009801.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 697459 leuS 5586204 leuS Escherichia coli E24377A leucyl-tRNA synthetase YP_001461810.1 694877 R 331111 CDS YP_001461811.1 157158052 5589276 697694..698176 1 NC_009801.1 identified by similarity to SP:P0AAT9; match to protein family HMM PF07295; hypothetical protein 698176 5589276 EcE24377A_0669 Escherichia coli E24377A hypothetical protein YP_001461811.1 697694 D 331111 CDS YP_001461812.1 157156509 5587105 complement(698246..699103) 1 NC_009801.1 identified by similarity to GB:AAV88692.1; match to protein family HMM PF08238; hypothetical protein 699103 5587105 EcE24377A_0670 Escherichia coli E24377A hypothetical protein YP_001461812.1 698246 R 331111 CDS YP_001461813.1 157156200 5590542 complement(699051..699224) 1 NC_009801.1 identified by glimmer; hypothetical protein 699224 5590542 EcE24377A_0671 Escherichia coli E24377A hypothetical protein YP_001461813.1 699051 R 331111 CDS YP_001461814.1 157156748 5586482 699214..699354 1 NC_009801.1 identified by glimmer; hypothetical protein 699354 5586482 EcE24377A_0672 Escherichia coli E24377A hypothetical protein YP_001461814.1 699214 D 331111 CDS YP_001461815.1 157155864 5589710 699388..700095 1 NC_009801.1 identified by similarity to SP:P77627; match to protein family HMM PF06889; hypothetical protein 700095 5589710 EcE24377A_0673 Escherichia coli E24377A hypothetical protein YP_001461815.1 699388 D 331111 CDS YP_001461816.1 157155170 5588449 700092..701519 1 NC_009801.1 identified by match to protein family HMM PF00226; DnaJ domain-containing protein 701519 5588449 EcE24377A_0674 Escherichia coli E24377A DnaJ domain-containing protein YP_001461816.1 700092 D 331111 CDS YP_001461817.1 157159260 5587478 complement(701529..702083) 1 NC_009801.1 identified by similarity to GB:BAB34108.1; match to protein family HMM PF08238; hypothetical protein 702083 5587478 EcE24377A_0675 Escherichia coli E24377A hypothetical protein YP_001461817.1 701529 R 331111 CDS YP_001461818.1 157158446 5590161 702185..702892 1 NC_009801.1 identified by similarity to SP:P77427; match to protein family HMM PF06889; hypothetical protein 702892 5590161 EcE24377A_0676 Escherichia coli E24377A hypothetical protein YP_001461818.1 702185 D 331111 CDS YP_001461819.1 157157945 5587653 702889..704340 1 NC_009801.1 identified by match to protein family HMM PF00226; DnaJ domain-containing protein 704340 5587653 EcE24377A_0677 Escherichia coli E24377A DnaJ domain-containing protein YP_001461819.1 702889 D 331111 CDS YP_001461820.1 157157133 5586020 complement(704400..706070) 1 NC_009801.1 identified by match to protein family HMM PF00012; molecular chaperone DnaK 706070 hscC 5586020 hscC Escherichia coli E24377A molecular chaperone DnaK YP_001461820.1 704400 R 331111 CDS YP_001461821.1 157156069 5589986 complement(706154..707089) 1 NC_009801.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 707089 rihA 5589986 rihA Escherichia coli E24377A ribonucleoside hydrolase 1 YP_001461821.1 706154 R 331111 CDS YP_001461822.1 157156502 5588295 complement(707207..707932) 1 NC_009801.1 identified by match to protein family HMM PF00005; glutamate/aspartate ABC transporter ATP-binding protein 707932 gltL 5588295 gltL Escherichia coli E24377A glutamate/aspartate ABC transporter ATP-binding protein YP_001461822.1 707207 R 331111 CDS YP_001461823.1 157155672 5588342 complement(707932..708606) 1 NC_009801.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamate/aspartate ABC transporter permease GltK 708606 gltK 5588342 gltK Escherichia coli E24377A glutamate/aspartate ABC transporter permease GltK YP_001461823.1 707932 R 331111 CDS YP_001461824.1 157155111 5587029 complement(708606..709346) 1 NC_009801.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamate/aspartate ABC transporter permease GltJ 709346 gltJ 5587029 gltJ Escherichia coli E24377A glutamate/aspartate ABC transporter permease GltJ YP_001461824.1 708606 R 331111 CDS YP_001461825.1 157157607 5589148 complement(709516..710424) 1 NC_009801.1 identified by match to protein family HMM PF00497; glutamate and aspartate transporter subunit 710424 gltI 5589148 gltI Escherichia coli E24377A glutamate and aspartate transporter subunit YP_001461825.1 709516 R 331111 CDS YP_001461826.1 157159333 5588834 710559..710681 1 NC_009801.1 identified by glimmer; hypothetical protein 710681 5588834 EcE24377A_0684 Escherichia coli E24377A hypothetical protein YP_001461826.1 710559 D 331111 CDS YP_001461827.1 157159255 5589471 710879..712756 1 NC_009801.1 identified by match to protein family HMM PF01694; match to protein family HMM TIGR02276; S54 family peptidase 712756 5589471 EcE24377A_0685 Escherichia coli E24377A S54 family peptidase YP_001461827.1 710879 D 331111 CDS YP_001461828.1 157158732 5587043 complement(712834..714372) 1 NC_009801.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 714372 lnt 5587043 lnt Escherichia coli E24377A apolipoprotein N-acyltransferase YP_001461828.1 712834 R 331111 CDS YP_001461829.1 157154891 5590390 complement(714397..715275) 1 NC_009801.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; magnesium and cobalt efflux protein CorC 715275 corC 5590390 corC Escherichia coli E24377A magnesium and cobalt efflux protein CorC YP_001461829.1 714397 R 331111 CDS YP_001461830.1 157156781 5588216 complement(715365..715832) 1 NC_009801.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043; metalloprotease 715832 5588216 EcE24377A_0688 Escherichia coli E24377A metalloprotease YP_001461830.1 715365 R 331111 CDS YP_001461831.1 157157740 5588640 complement(715829..716869) 1 NC_009801.1 identified by match to protein family HMM PF02562; PhoH family protein 716869 5588640 EcE24377A_0689 Escherichia coli E24377A PhoH family protein YP_001461831.1 715829 R 331111 CDS YP_001461832.1 157159267 5590736 716888..717031 1 NC_009801.1 identified by glimmer; hypothetical protein 717031 5590736 EcE24377A_0691 Escherichia coli E24377A hypothetical protein YP_001461832.1 716888 D 331111 CDS YP_001461833.1 157157673 5586142 complement(717022..718446) 1 NC_009801.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 718446 miaB 5586142 miaB Escherichia coli E24377A (dimethylallyl)adenosine tRNA methylthiotransferase YP_001461833.1 717022 R 331111 CDS YP_001461834.1 157158593 5588753 718592..719767 1 NC_009801.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 719767 ubiF 5588753 ubiF Escherichia coli E24377A 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_001461834.1 718592 D 331111 CDS YP_001461835.1 157156873 5587367 complement(720893..722557) 1 NC_009801.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 722557 asnB 5587367 asnB Escherichia coli E24377A asparagine synthetase B YP_001461835.1 720893 R 331111 CDS YP_001461836.1 157155303 5587832 complement(722814..723566) 1 NC_009801.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01460; UMP phosphatase 723566 nagD 5587832 nagD Escherichia coli E24377A UMP phosphatase YP_001461836.1 722814 R 331111 CDS YP_001461837.1 157158174 5589955 complement(723614..724834) 1 NC_009801.1 identified by match to protein family HMM PF00480; N-acetylglucosamine repressor 724834 nagC 5589955 nagC Escherichia coli E24377A N-acetylglucosamine repressor YP_001461837.1 723614 R 331111 CDS YP_001461838.1 157156004 5586629 complement(724843..725991) 1 NC_009801.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 725991 nagA 5586629 nagA Escherichia coli E24377A N-acetylglucosamine-6-phosphate deacetylase YP_001461838.1 724843 R 331111 CDS YP_001461839.1 157159152 5586783 complement(726051..726851) 1 NC_009801.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 726851 nagB 5586783 nagB Escherichia coli E24377A glucosamine-6-phosphate deaminase YP_001461839.1 726051 R 331111 CDS YP_001461840.1 157155109 5587295 727184..729130 1 NC_009801.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunit IIABC 729130 nagE 5587295 nagE Escherichia coli E24377A PTS system N-acetyl glucosamine specific transporter subunit IIABC YP_001461840.1 727184 D 331111 CDS YP_001461841.1 157157357 5587978 complement(729100..729222) 1 NC_009801.1 identified by glimmer; hypothetical protein 729222 5587978 EcE24377A_0704 Escherichia coli E24377A hypothetical protein YP_001461841.1 729100 R 331111 CDS YP_001461842.1 157159259 5586917 729333..730997 1 NC_009801.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 730997 glnS 5586917 glnS Escherichia coli E24377A glutaminyl-tRNA synthetase YP_001461842.1 729333 D 331111 CDS YP_001461843.1 157156481 5590160 complement(731000..731185) 1 NC_009801.1 identified by glimmer; hypothetical protein 731185 5590160 EcE24377A_0707 Escherichia coli E24377A hypothetical protein YP_001461843.1 731000 R 331111 CDS YP_001461844.1 157157009 5589659 complement(731148..731252) 1 NC_009801.1 identified by glimmer; hypothetical protein 731252 5589659 EcE24377A_0708 Escherichia coli E24377A hypothetical protein YP_001461844.1 731148 R 331111 CDS YP_001461845.1 157158347 5586646 731443..732849 1 NC_009801.1 identified by match to protein family HMM PF03573; porin 732849 oprD 5586646 oprD Escherichia coli E24377A porin YP_001461845.1 731443 D 331111 CDS YP_001461846.1 157155578 5586254 732899..733225 1 NC_009801.1 lipoprotein 733225 5586254 EcE24377A_0710 Escherichia coli E24377A lipoprotein YP_001461846.1 732899 D 331111 CDS YP_001461847.1 157156224 5586769 complement(733310..733756) 1 NC_009801.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 733756 fur 5586769 fur Escherichia coli E24377A ferric uptake regulator YP_001461847.1 733310 R 331111 CDS YP_001461848.1 157157770 5586978 complement(734045..734692) 1 NC_009801.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 734692 fldA 5586978 fldA Escherichia coli E24377A flavodoxin FldA YP_001461848.1 734045 R 331111 CDS YP_001461849.1 157154857 5590676 complement(734715..735008) 1 NC_009801.1 identified by match to protein family HMM PF01402; LexA regulated protein 735008 5590676 EcE24377A_0713 Escherichia coli E24377A LexA regulated protein YP_001461849.1 734715 R 331111 CDS YP_001461850.1 157156449 5589739 complement(735148..735912) 1 NC_009801.1 identified by match to protein family HMM PF00561; match to protein family HMM PF07819; hypothetical protein 735912 5589739 EcE24377A_0714 Escherichia coli E24377A hypothetical protein YP_001461850.1 735148 R 331111 CDS YP_001461851.1 157155619 5588076 736097..736642 1 NC_009801.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 736642 seqA 5588076 seqA Escherichia coli E24377A replication initiation regulator SeqA YP_001461851.1 736097 D 331111 CDS YP_001461852.1 157155077 5587018 736668..738308 1 NC_009801.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 738308 pgm 5587018 pgm Escherichia coli E24377A phosphoglucomutase YP_001461852.1 736668 D 331111 CDS YP_001461853.1 157159107 5587738 complement(738364..739683) 1 NC_009801.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 739683 potE 5587738 potE Escherichia coli E24377A putrescine transporter YP_001461853.1 738364 R 331111 CDS YP_001461854.1 157158479 5590857 complement(739680..741887) 1 NC_009801.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; ornithine decarboxylase 741887 speF 5590857 speF Escherichia coli E24377A ornithine decarboxylase YP_001461854.1 739680 R 331111 CDS YP_001461855.1 157154803 5590401 742412..742546 1 NC_009801.1 identified by similarity to GB:AAN42241.1; hypothetical protein 742546 5590401 EcE24377A_0719 Escherichia coli E24377A hypothetical protein YP_001461855.1 742412 D 331111 CDS YP_001461856.1 157155566 5587709 complement(742568..743245) 1 NC_009801.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE 743245 kdpE 5587709 kdpE Escherichia coli E24377A DNA-binding transcriptional activator KdpE YP_001461856.1 742568 R 331111 CDS YP_001461857.1 157157107 5585937 complement(743242..745926) 1 NC_009801.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD 745926 kdpD 5585937 kdpD Escherichia coli E24377A sensor protein KdpD YP_001461857.1 743242 R 331111 CDS YP_001461858.1 157156599 5587111 complement(745919..746491) 1 NC_009801.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 746491 kdpC 5587111 kdpC Escherichia coli E24377A potassium-transporting ATPase subunit C YP_001461858.1 745919 R 331111 CDS YP_001461859.1 157159118 5589994 complement(746500..748548) 1 NC_009801.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 748548 kdpB 5589994 kdpB Escherichia coli E24377A potassium-transporting ATPase subunit B YP_001461859.1 746500 R 331111 CDS YP_001461860.1 157158452 5587423 complement(748571..750244) 1 NC_009801.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 750244 kdpA 5587423 kdpA Escherichia coli E24377A potassium-transporting ATPase subunit A YP_001461860.1 748571 R 331111 CDS YP_001461861.1 157155728 5587180 complement(750244..750447) 1 NC_009801.1 identified by match to protein family HMM TIGR02115; K+-transporting ATPase subunit F 750447 kdpF 5587180 kdpF Escherichia coli E24377A K+-transporting ATPase subunit F YP_001461861.1 750244 R 331111 CDS YP_001461862.1 157155052 5587162 750645..750851 1 NC_009801.1 identified by similarity to GB:AAN79258.1; hypothetical protein 750851 5587162 EcE24377A_0726 Escherichia coli E24377A hypothetical protein YP_001461862.1 750645 D 331111 CDS YP_001461863.1 157155232 5586199 751094..755287 1 NC_009801.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; protein rhsA 755287 5586199 EcE24377A_0727 Escherichia coli E24377A protein rhsA YP_001461863.1 751094 D 331111 CDS YP_001461864.1 157156917 5589111 755731..757164 1 NC_009801.1 identified by match to protein family HMM PF03527; RHS domain-containing protein 757164 5589111 EcE24377A_0728 Escherichia coli E24377A RHS domain-containing protein YP_001461864.1 755731 D 331111 CDS YP_001461865.1 157157299 5590755 757161..757730 1 NC_009801.1 identified by glimmer; hypothetical protein 757730 5590755 EcE24377A_0729 Escherichia coli E24377A hypothetical protein YP_001461865.1 757161 D 331111 CDS YP_001461866.1 157158968 5590833 757956..758210 1 NC_009801.1 identified by similarity to GB:BAA35363.1; ISEc2, transposase 758210 5590833 EcE24377A_0730 Escherichia coli E24377A ISEc2, transposase YP_001461866.1 757956 D 331111 CDS YP_001461867.1 157158604 5588227 759245..759754 1 NC_009801.1 identified by similarity to GB:AAN79259.1; match to protein family HMM PF08349; hypothetical protein 759754 5588227 EcE24377A_0732 Escherichia coli E24377A hypothetical protein YP_001461867.1 759245 D 331111 CDS YP_001461868.1 157154932 5586035 759751..761169 1 NC_009801.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 761169 phrB 5586035 phrB Escherichia coli E24377A deoxyribodipyrimidine photolyase YP_001461868.1 759751 D 331111 CDS YP_001461869.1 157156984 5589934 complement(761211..762692) 1 NC_009801.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; amino acid/peptide transporter 762692 5589934 EcE24377A_0734 Escherichia coli E24377A amino acid/peptide transporter YP_001461869.1 761211 R 331111 CDS YP_001461870.1 157157712 5589598 762963..763706 1 NC_009801.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486; hydrolase-oxidase 763706 5589598 EcE24377A_0735 Escherichia coli E24377A hydrolase-oxidase YP_001461870.1 762963 D 331111 CDS YP_001461871.1 157157256 5587117 763729..764385 1 NC_009801.1 identified by match to protein family HMM PF02682; match to protein family HMM TIGR00370; allophanate hydrolase, subunit 1 764385 5587117 EcE24377A_0736 Escherichia coli E24377A allophanate hydrolase, subunit 1 YP_001461871.1 763729 D 331111 CDS YP_001461872.1 157159077 5589396 764379..765311 1 NC_009801.1 identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724; allophanate hydrolase subunit 2 765311 5589396 EcE24377A_0737 Escherichia coli E24377A allophanate hydrolase subunit 2 YP_001461872.1 764379 D 331111 CDS YP_001461873.1 157158558 5587982 765301..766035 1 NC_009801.1 identified by match to protein family HMM PF03746; LamB/YcsF family protein 766035 5587982 EcE24377A_0738 Escherichia coli E24377A LamB/YcsF family protein YP_001461873.1 765301 D 331111 CDS YP_001461874.1 157155050 5589167 766071..766862 1 NC_009801.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 766862 nei 5589167 nei Escherichia coli E24377A endonuclease VIII YP_001461874.1 766071 D 331111 CDS YP_001461875.1 157155342 5587356 complement(768056..769117) 1 NC_009801.1 identified by similarity to GB:AAZ87425.1; hypothetical protein 769117 5587356 EcE24377A_0742 Escherichia coli E24377A hypothetical protein YP_001461875.1 768056 R 331111 CDS YP_001461876.1 157156567 5589300 complement(769114..769845) 1 NC_009801.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; periplasmic pilus chaperone family protein 769845 5589300 EcE24377A_0743 Escherichia coli E24377A periplasmic pilus chaperone family protein YP_001461876.1 769114 R 331111 CDS YP_001461877.1 157156026 5588548 complement(769860..772361) 1 NC_009801.1 identified by match to protein family HMM PF00577; fimbrial usher family protein 772361 5588548 EcE24377A_0744 Escherichia coli E24377A fimbrial usher family protein YP_001461877.1 769860 R 331111 CDS YP_001461878.1 157158772 5586553 complement(772370..772936) 1 NC_009801.1 identified by similarity to SP:P04128; match to protein family HMM PF00419; type 1 fimbrial protein 772936 5586553 EcE24377A_0745 Escherichia coli E24377A type 1 fimbrial protein YP_001461878.1 772370 R 331111 CDS YP_001461879.1 157158265 5587665 complement(773008..773136) 1 NC_009801.1 identified by glimmer; hypothetical protein 773136 5587665 EcE24377A_0746 Escherichia coli E24377A hypothetical protein YP_001461879.1 773008 R 331111 CDS YP_001461880.1 157155745 5588872 complement(773327..774610) 1 NC_009801.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 774610 gltA 5588872 gltA Escherichia coli E24377A type II citrate synthase YP_001461880.1 773327 R 331111 CDS YP_001461881.1 157154902 5590581 775304..775708 1 NC_009801.1 identified by match to protein family HMM PF01127; match to protein family HMM TIGR02970; succinate dehydrogenase cytochrome b556 large membrane subunit 775708 sdhC 5590581 sdhC Escherichia coli E24377A succinate dehydrogenase cytochrome b556 large membrane subunit YP_001461881.1 775304 D 331111 CDS YP_001461882.1 157156814 5590116 775702..776049 1 NC_009801.1 identified by match to protein family HMM TIGR02968; succinate dehydrogenase cytochrome b556 small membrane subunit 776049 sdhD 5590116 sdhD Escherichia coli E24377A succinate dehydrogenase cytochrome b556 small membrane subunit YP_001461882.1 775702 D 331111 CDS YP_001461883.1 157156147 5587072 776049..777815 1 NC_009801.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 777815 sdhA 5587072 sdhA Escherichia coli E24377A succinate dehydrogenase flavoprotein subunit YP_001461883.1 776049 D 331111 CDS YP_001461884.1 157156213 5590181 777831..778547 1 NC_009801.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 778547 sdhB 5590181 sdhB Escherichia coli E24377A succinate dehydrogenase iron-sulfur subunit YP_001461884.1 777831 D 331111 CDS YP_001461885.1 157155363 5587339 778748..781549 1 NC_009801.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 781549 sucA 5587339 sucA Escherichia coli E24377A 2-oxoglutarate dehydrogenase E1 YP_001461885.1 778748 D 331111 CDS YP_001461886.1 157157585 5589616 781564..782781 1 NC_009801.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 782781 sucB 5589616 sucB Escherichia coli E24377A dihydrolipoamide succinyltransferase YP_001461886.1 781564 D 331111 CDS YP_001461887.1 157156644 5585909 782875..784041 1 NC_009801.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 784041 sucC 5585909 sucC Escherichia coli E24377A succinyl-CoA synthetase subunit beta YP_001461887.1 782875 D 331111 CDS YP_001461888.1 157158239 5587454 784041..784910 1 NC_009801.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 784910 sucD 5587454 sucD Escherichia coli E24377A succinyl-CoA synthetase subunit alpha YP_001461888.1 784041 D 331111 CDS YP_001461889.1 157157593 5587788 complement(785014..785736) 1 NC_009801.1 regulates the succiny-lCoA synthetase operon; DNA-binding transcriptional repressor MngR 785736 farR 5587788 farR Escherichia coli E24377A DNA-binding transcriptional repressor MngR YP_001461889.1 785014 R 331111 CDS YP_001461890.1 157159304 5588842 785905..787821 1 NC_009801.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC 787821 5588842 EcE24377A_0757 Escherichia coli E24377A PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC YP_001461890.1 785905 D 331111 CDS YP_001461891.1 157158631 5588477 787839..790472 1 NC_009801.1 identified by match to protein family HMM PF01074; match to protein family HMM PF07748; alpha-mannosidase 790472 5588477 EcE24377A_0758 Escherichia coli E24377A alpha-mannosidase YP_001461891.1 787839 D 331111 CDS YP_001461892.1 157155558 5586785 complement(790801..790905) 1 NC_009801.1 identified by glimmer; hypothetical protein 790905 5586785 EcE24377A_0760 Escherichia coli E24377A hypothetical protein YP_001461892.1 790801 R 331111 CDS YP_001461893.1 157156610 5590437 791319..792887 1 NC_009801.1 identified by match to protein family HMM PF01654; cytochrome d ubiquinol oxidase, subunit I 792887 cydA 5590437 cydA Escherichia coli E24377A cytochrome d ubiquinol oxidase, subunit I YP_001461893.1 791319 D 331111 CDS YP_001461894.1 157158603 5589992 792903..794042 1 NC_009801.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203; cytochrome d ubiquinol oxidase, subunit II 794042 cydB 5589992 cydB Escherichia coli E24377A cytochrome d ubiquinol oxidase, subunit II YP_001461894.1 792903 D 331111 CDS YP_001461895.1 157159220 5586034 794057..794170 1 NC_009801.1 identified by match to protein family HMM PF08173; match to protein family HMM TIGR02106; cyd operon protein YbgT 794170 5586034 EcE24377A_0763 Escherichia coli E24377A cyd operon protein YbgT YP_001461895.1 794057 D 331111 CDS YP_001461896.1 157154913 5590715 794170..794463 1 NC_009801.1 identified by match to protein family HMM TIGR02112; hypothetical protein 794463 5590715 EcE24377A_0764 Escherichia coli E24377A hypothetical protein YP_001461896.1 794170 D 331111 CDS YP_001461897.1 157155477 5587219 794613..795017 1 NC_009801.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase 795017 ybgC 5587219 ybgC Escherichia coli E24377A acyl-CoA thioester hydrolase YP_001461897.1 794613 D 331111 CDS YP_001461898.1 157156530 5589232 795014..795706 1 NC_009801.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 795706 tolQ 5589232 tolQ Escherichia coli E24377A colicin uptake protein TolQ YP_001461898.1 795014 D 331111 CDS YP_001461899.1 157154910 5587282 795710..796138 1 NC_009801.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 796138 tolR 5587282 tolR Escherichia coli E24377A colicin uptake protein TolR YP_001461899.1 795710 D 331111 CDS YP_001461900.1 157158717 5587336 796203..797501 1 NC_009801.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 797501 tolA 5587336 tolA Escherichia coli E24377A cell envelope integrity inner membrane protein TolA YP_001461900.1 796203 D 331111 CDS YP_001461901.1 157154962 5589305 797634..798926 1 NC_009801.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 798926 tolB 5589305 tolB Escherichia coli E24377A translocation protein TolB YP_001461901.1 797634 D 331111 CDS YP_001461902.1 157157682 5590091 798961..799482 1 NC_009801.1 identified by match to protein family HMM PF00691; match to protein family HMM TIGR02802; peptidoglycan-associated outer membrane lipoprotein 799482 pal 5590091 pal Escherichia coli E24377A peptidoglycan-associated outer membrane lipoprotein YP_001461902.1 798961 D 331111 CDS YP_001461903.1 157158211 5590492 799492..800283 1 NC_009801.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 800283 ygbF 5590492 ygbF Escherichia coli E24377A tol-pal system protein YbgF YP_001461903.1 799492 D 331111 CDS YP_001461904.1 157156025 5587082 801549..802592 1 NC_009801.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 802592 nadA 5587082 nadA Escherichia coli E24377A quinolinate synthetase YP_001461904.1 801549 D 331111 CDS YP_001461905.1 157156542 5587151 802645..803349 1 NC_009801.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528; nicotinamide mononucleotide transporter PnuC 803349 pnuC 5587151 pnuC Escherichia coli E24377A nicotinamide mononucleotide transporter PnuC YP_001461905.1 802645 D 331111 CDS YP_001461906.1 157156058 5589948 complement(803346..804287) 1 NC_009801.1 involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB 804287 zitB 5589948 zitB Escherichia coli E24377A zinc transporter ZitB YP_001461906.1 803346 R 331111 CDS YP_001461907.1 157156580 5586918 complement(804401..804781) 1 NC_009801.1 hypothetical protein 804781 5586918 EcE24377A_0780 Escherichia coli E24377A hypothetical protein YP_001461907.1 804401 R 331111 CDS YP_001461908.1 157154975 5586458 805097..806149 1 NC_009801.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 806149 aroG 5586458 aroG Escherichia coli E24377A phospho-2-dehydro-3-deoxyheptonate aldolase YP_001461908.1 805097 D 331111 CDS YP_001461909.1 157155502 5587326 complement(806308..807060) 1 NC_009801.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 807060 gpmA 5587326 gpmA Escherichia coli E24377A phosphoglyceromutase YP_001461909.1 806308 R 331111 CDS YP_001461910.1 157157316 5586111 complement(807262..808302) 1 NC_009801.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 808302 galM 5586111 galM Escherichia coli E24377A aldose 1-epimerase YP_001461910.1 807262 R 331111 CDS YP_001461911.1 157158993 5586335 complement(808296..809444) 1 NC_009801.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 809444 galK 5586335 galK Escherichia coli E24377A galactokinase YP_001461911.1 808296 R 331111 CDS YP_001461912.1 157158334 5588025 complement(809448..810494) 1 NC_009801.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 810494 galT 5588025 galT Escherichia coli E24377A galactose-1-phosphate uridylyltransferase YP_001461912.1 809448 R 331111 CDS YP_001461913.1 157155911 5590101 complement(810504..811520) 1 NC_009801.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF05368; match to protein family HMM PF07993; match to protein family HMM TIGR01179; UDP-galactose-4-epimerase 811520 galE 5590101 galE Escherichia coli E24377A UDP-galactose-4-epimerase YP_001461913.1 810504 R 331111 CDS YP_001461914.1 157155198 5586971 complement(811781..813253) 1 NC_009801.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF 813253 modF 5586971 modF Escherichia coli E24377A molybdenum transport ATP-binding protein ModF YP_001461914.1 811781 R 331111 CDS YP_001461915.1 157156950 5587957 complement(813321..814109) 1 NC_009801.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE 814109 modE 5587957 modE Escherichia coli E24377A DNA-binding transcriptional regulator ModE YP_001461915.1 813321 R 331111 CDS YP_001461916.1 157157941 5590684 814238..814387 1 NC_009801.1 hypothetical protein 814387 5590684 EcE24377A_0789 Escherichia coli E24377A hypothetical protein YP_001461916.1 814238 D 331111 CDS YP_001461917.1 157157330 5587973 814553..815326 1 NC_009801.1 with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 815326 modA 5587973 modA Escherichia coli E24377A molybdate transporter periplasmic protein YP_001461917.1 814553 D 331111 CDS YP_001461918.1 157159018 5588736 815326..816015 1 NC_009801.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 816015 modB 5588736 modB Escherichia coli E24377A molybdate ABC transporter permease YP_001461918.1 815326 D 331111 CDS YP_001461919.1 157158790 5587838 816018..817076 1 NC_009801.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 817076 modC 5587838 modC Escherichia coli E24377A molybdate transporter ATP-binding protein YP_001461919.1 816018 D 331111 CDS YP_001461920.1 157158444 5587975 complement(817077..817895) 1 NC_009801.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 817895 ybhA 5587975 ybhA Escherichia coli E24377A phosphotransferase YP_001461920.1 817077 R 331111 CDS YP_001461921.1 157155676 5590523 818050..819045 1 NC_009801.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 819045 pgl 5590523 pgl Escherichia coli E24377A 6-phosphogluconolactonase YP_001461921.1 818050 D 331111 CDS YP_001461922.1 157155270 5586348 complement(819086..820039) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 820039 5586348 EcE24377A_0795 Escherichia coli E24377A LysR family transcriptional regulator YP_001461922.1 819086 R 331111 CDS YP_001461923.1 157156991 5586564 820223..821275 1 NC_009801.1 identified by similarity to SP:P0AAV8; match to protein family HMM PF04303; hypothetical protein 821275 5586564 EcE24377A_0796 Escherichia coli E24377A hypothetical protein YP_001461923.1 820223 D 331111 CDS YP_001461924.1 157156671 5588915 821351..822784 1 NC_009801.1 identified by match to protein family HMM PF00939; match to protein family HMM PF03600; match to protein family HMM TIGR00785; anion transporter 822784 5588915 EcE24377A_0797 Escherichia coli E24377A anion transporter YP_001461924.1 821351 D 331111 CDS YP_001461925.1 157155988 5587820 822943..825228 1 NC_009801.1 identified by match to protein family HMM PF00330; match to protein family HMM PF00694; hypothetical protein 825228 5587820 EcE24377A_0798 Escherichia coli E24377A hypothetical protein YP_001461925.1 822943 D 331111 CDS YP_001461926.1 157157926 5585974 complement(825462..826745) 1 NC_009801.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase; pectinesterase 826745 5585974 EcE24377A_0799 Escherichia coli E24377A pectinesterase YP_001461926.1 825462 R 331111 CDS YP_001461927.1 157157271 5587327 complement(826880..827950) 1 NC_009801.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM PF09003; phage integrase 827950 5587327 EcE24377A_0800 Escherichia coli E24377A phage integrase YP_001461927.1 826880 R 331111 CDS YP_001461928.1 157159356 5588816 complement(829409..829630) 1 NC_009801.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02419; phage/conjugal plasmid C-4 type zinc finger protein 829630 5588816 EcE24377A_0801 Escherichia coli E24377A phage/conjugal plasmid C-4 type zinc finger protein YP_001461928.1 829409 R 331111 CDS YP_001461929.1 157158857 5590682 complement(829637..829726) 1 NC_009801.1 identified by glimmer; hypothetical protein 829726 5590682 EcE24377A_0802 Escherichia coli E24377A hypothetical protein YP_001461929.1 829637 R 331111 CDS YP_001461930.1 157158185 5589827 complement(829729..830010) 1 NC_009801.1 identified by similarity to GB:BAB34229.1; hypothetical protein 830010 5589827 EcE24377A_0803 Escherichia coli E24377A hypothetical protein YP_001461930.1 829729 R 331111 CDS YP_001461931.1 157156284 5586462 complement(830364..831044) 1 NC_009801.1 identified by similarity to SP:P03697; exonuclease 831044 exo 5586462 exo Escherichia coli E24377A exonuclease YP_001461931.1 830364 R 331111 CDS YP_001461932.1 157155950 5590206 complement(831041..831826) 1 NC_009801.1 identified by similarity to SP:P03698; match to protein family HMM PF03837; match to protein family HMM TIGR01913; phage recombination protein Bet 831826 bet 5590206 bet Escherichia coli E24377A phage recombination protein Bet YP_001461932.1 831041 R 331111 CDS YP_001461933.1 157155193 5587901 complement(831832..832128) 1 NC_009801.1 identified by similarity to SP:P03702; match to protein family HMM PF06064; host-nuclease inhibitor protein Gam 832128 gam 5587901 gam Escherichia coli E24377A host-nuclease inhibitor protein Gam YP_001461933.1 831832 R 331111 CDS YP_001461934.1 157154934 5588162 complement(832204..832410) 1 NC_009801.1 identified by similarity to SP:P38393; protein KiL 832410 kiL 5588162 kiL Escherichia coli E24377A protein KiL YP_001461934.1 832204 R 331111 CDS YP_001461935.1 157155496 5590038 complement(833008..833763) 1 NC_009801.1 identified by match to protein family HMM PF00717; match to protein family HMM PF01381; repressor protein 833763 5590038 EcE24377A_0808 Escherichia coli E24377A repressor protein YP_001461935.1 833008 R 331111 CDS YP_001461936.1 157158727 5588462 834102..834641 1 NC_009801.1 identified by match to protein family HMM PF06254; hypothetical protein 834641 5588462 EcE24377A_0809 Escherichia coli E24377A hypothetical protein YP_001461936.1 834102 D 331111 CDS YP_001461937.1 157156359 5590281 835654..836355 1 NC_009801.1 identified by match to protein family HMM PF06992; replication protein P 836355 5590281 EcE24377A_0811 Escherichia coli E24377A replication protein P YP_001461937.1 835654 D 331111 CDS YP_001461938.1 157156903 5590725 836352..836654 1 NC_009801.1 hypothetical protein 836654 5590725 EcE24377A_0812 Escherichia coli E24377A hypothetical protein YP_001461938.1 836352 D 331111 CDS YP_001461939.1 157158420 5586437 836722..837054 1 NC_009801.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 837054 emrE 5586437 emrE Escherichia coli E24377A multidrug efflux protein YP_001461939.1 836722 D 331111 CDS YP_001461940.1 157157333 5586778 complement(839146..840684) 1 NC_009801.1 identified by match to protein family HMM PF03050; IS66 family transposase 840684 5586778 EcE24377A_0815 Escherichia coli E24377A IS66 family transposase YP_001461940.1 839146 R 331111 CDS YP_001461941.1 157157743 5589667 complement(840734..841081) 1 NC_009801.1 identified by match to protein family HMM PF05717; IS66 family orf2 841081 5589667 EcE24377A_0816 Escherichia coli E24377A IS66 family orf2 YP_001461941.1 840734 R 331111 CDS YP_001461942.1 157156413 5590204 complement(841078..841467) 1 NC_009801.1 identified by match to protein family HMM PF01527; IS66 family orf1 841467 5590204 EcE24377A_0817 Escherichia coli E24377A IS66 family orf1 YP_001461942.1 841078 R 331111 CDS YP_001461943.1 157157071 5589203 841896..842678 1 NC_009801.1 identified by glimmer; hypothetical protein 842678 5589203 EcE24377A_0818 Escherichia coli E24377A hypothetical protein YP_001461943.1 841896 D 331111 CDS YP_001461944.1 157155599 5588429 842871..843326 1 NC_009801.1 DLP12 prophage; hypothetical protein 843326 5588429 EcE24377A_0819 Escherichia coli E24377A hypothetical protein YP_001461944.1 842871 D 331111 CDS YP_001461945.1 157155648 5587192 843489..843779 1 NC_009801.1 identified by match to protein family HMM PF07102; hypothetical protein 843779 5587192 EcE24377A_0820 Escherichia coli E24377A hypothetical protein YP_001461945.1 843489 D 331111 CDS YP_001461946.1 157158407 5588919 843776..844138 1 NC_009801.1 DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 844138 rusA 5588919 rusA Escherichia coli E24377A endodeoxyribonuclease RUS YP_001461946.1 843776 D 331111 CDS YP_001461947.1 157158918 5588934 844138..844275 1 NC_009801.1 identified by similarity to SP:Q47272; hypothetical protein 844275 5588934 EcE24377A_0822 Escherichia coli E24377A hypothetical protein YP_001461947.1 844138 D 331111 CDS YP_001461948.1 157159439 5590567 844361..844744 1 NC_009801.1 identified by similarity to SP:Q47274; match to protein family HMM PF06530; phage antitermination Q 844744 5590567 EcE24377A_0823 Escherichia coli E24377A phage antitermination Q YP_001461948.1 844361 D 331111 CDS YP_001461949.1 157157576 5588743 complement(844933..846015) 1 NC_009801.1 identified by similarity to SP:P07238; match to protein family HMM PF00267; outer membrane porin protein LC 846015 5588743 EcE24377A_0824 Escherichia coli E24377A outer membrane porin protein LC YP_001461949.1 844933 R 331111 CDS YP_001461950.1 157155693 5587528 complement(845942..846076) 1 NC_009801.1 identified by glimmer; hypothetical protein 846076 5587528 EcE24377A_0825 Escherichia coli E24377A hypothetical protein YP_001461950.1 845942 R 331111 CDS YP_001461951.1 157158563 5590489 846604..846819 1 NC_009801.1 identified by match to protein family HMM PF04971; lysis protein S 846819 5590489 EcE24377A_0826 Escherichia coli E24377A lysis protein S YP_001461951.1 846604 D 331111 CDS YP_001461952.1 157158856 5586299 846819..847316 1 NC_009801.1 identified by match to protein family HMM PF00959; phage lysozyme 847316 5586299 EcE24377A_0827 Escherichia coli E24377A phage lysozyme YP_001461952.1 846819 D 331111 CDS YP_001461953.1 157158333 5589826 847313..847750 1 NC_009801.1 identified by match to protein family HMM PF03245; bacteriophage lysis protein 847750 5589826 EcE24377A_0828 Escherichia coli E24377A bacteriophage lysis protein YP_001461953.1 847313 D 331111 CDS YP_001461954.1 157157776 5590100 847955..848476 1 NC_009801.1 identified by match to protein family HMM PF04383; KilA domain-containing protein 848476 5590100 EcE24377A_0829 Escherichia coli E24377A KilA domain-containing protein YP_001461954.1 847955 D 331111 CDS YP_001461955.1 157157202 5586678 849632..849775 1 NC_009801.1 identified by glimmer; hypothetical protein 849775 5586678 EcE24377A_0830 Escherichia coli E24377A hypothetical protein YP_001461955.1 849632 D 331111 CDS YP_001461956.1 157156283 5586748 849915..850460 1 NC_009801.1 identified by match to protein family HMM PF07471; phage DNA packaging protein Nu1 850460 5586748 EcE24377A_0831 Escherichia coli E24377A phage DNA packaging protein Nu1 YP_001461956.1 849915 D 331111 CDS YP_001461957.1 157158554 5590205 850435..852024 1 NC_009801.1 identified by match to protein family HMM PF05876; phage terminase large subunit (GpA) 852024 5590205 EcE24377A_0832 Escherichia coli E24377A phage terminase large subunit (GpA) YP_001461957.1 850435 D 331111 CDS YP_001461958.1 157157994 5588856 852030..852875 1 NC_009801.1 identified by match to protein family HMM PF03335; match to protein family HMM PF07484; phage tail collar domain-containing protein 852875 5588856 EcE24377A_0833 Escherichia coli E24377A phage tail collar domain-containing protein YP_001461958.1 852030 D 331111 CDS YP_001461959.1 157154768 5590615 852875..853459 1 NC_009801.1 identified by similarity to SP:P03740; match to protein family HMM PF02413; tail fiber assembly protein 853459 5590615 EcE24377A_0834 Escherichia coli E24377A tail fiber assembly protein YP_001461959.1 852875 D 331111 CDS YP_001461960.1 157155149 5588160 complement(853533..854864) 1 NC_009801.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 854864 5588160 EcE24377A_0835 Escherichia coli E24377A diguanylate cyclase YP_001461960.1 853533 R 331111 CDS YP_001461961.1 157156918 5589227 complement(855610..856086) 1 NC_009801.1 YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein 856086 5589227 EcE24377A_0836 Escherichia coli E24377A kinase inhibitor protein YP_001461961.1 855610 R 331111 CDS YP_001461962.1 157156362 5587821 complement(856145..857434) 1 NC_009801.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 857434 bioA 5587821 bioA Escherichia coli E24377A adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_001461962.1 856145 R 331111 CDS YP_001461963.1 157157967 5590024 857521..858561 1 NC_009801.1 identified by similarity to SP:P12996; match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR00433; biotin synthase 858561 bioB 5590024 bioB Escherichia coli E24377A biotin synthase YP_001461963.1 857521 D 331111 CDS YP_001461964.1 157157327 5589604 858558..859712 1 NC_009801.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 859712 bioF 5589604 bioF Escherichia coli E24377A 8-amino-7-oxononanoate synthase YP_001461964.1 858558 D 331111 CDS YP_001461965.1 157157846 5589824 859699..860454 1 NC_009801.1 methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 860454 bioC 5589824 bioC Escherichia coli E24377A biotin biosynthesis protein BioC YP_001461965.1 859699 D 331111 CDS YP_001461966.1 157157171 5587098 860447..861124 1 NC_009801.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 861124 bioD 5587098 bioD Escherichia coli E24377A dithiobiotin synthetase YP_001461966.1 860447 D 331111 CDS YP_001461967.1 157155274 5586905 861703..863724 1 NC_009801.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 863724 uvrB 5586905 uvrB Escherichia coli E24377A excinuclease ABC subunit B YP_001461967.1 861703 D 331111 CDS YP_001461968.1 157159188 5587108 complement(863916..864824) 1 NC_009801.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826; hypothetical protein 864824 5587108 EcE24377A_0843 Escherichia coli E24377A hypothetical protein YP_001461968.1 863916 R 331111 CDS YP_001461969.1 157155416 5588116 865221..866210 1 NC_009801.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 866210 moaA 5588116 moaA Escherichia coli E24377A molybdenum cofactor biosynthesis protein A YP_001461969.1 865221 D 331111 CDS YP_001461970.1 157157361 5590274 866232..866744 1 NC_009801.1 identified by similarity to SP:P30746; match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR02667; molybdenum cofactor biosynthesis protein B 866744 moaB 5590274 moaB Escherichia coli E24377A molybdenum cofactor biosynthesis protein B YP_001461970.1 866232 D 331111 CDS YP_001461971.1 157158910 5586738 866747..867232 1 NC_009801.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 867232 moaC 5586738 moaC Escherichia coli E24377A molybdenum cofactor biosynthesis protein MoaC YP_001461971.1 866747 D 331111 CDS YP_001461972.1 157158419 5590730 867225..867470 1 NC_009801.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 867470 moaD 5590730 moaD Escherichia coli E24377A molybdopterin synthase small subunit YP_001461972.1 867225 D 331111 CDS YP_001461973.1 157159465 5586195 867472..867924 1 NC_009801.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 867924 moaE 5586195 moaE Escherichia coli E24377A molybdopterin guanine dinucleotide biosynthesis protein MoaE YP_001461973.1 867472 D 331111 CDS YP_001461974.1 157158723 5587378 868061..868765 1 NC_009801.1 identified by match to protein family HMM PF01027; hypothetical protein 868765 5587378 EcE24377A_0849 Escherichia coli E24377A hypothetical protein YP_001461974.1 868061 D 331111 CDS YP_001461975.1 157156612 5588522 complement(868857..868961) 1 NC_009801.1 identified by glimmer; hypothetical protein 868961 5588522 EcE24377A_0850 Escherichia coli E24377A hypothetical protein YP_001461975.1 868857 R 331111 CDS YP_001461976.1 157157693 5590073 868970..869683 1 NC_009801.1 ybhM; identified by match to protein family HMM PF01027; hypothetical protein 869683 5590073 EcE24377A_0851 Escherichia coli E24377A hypothetical protein YP_001461976.1 868970 D 331111 CDS YP_001461977.1 157155535 5587210 complement(869719..870675) 1 NC_009801.1 hypothetical protein 870675 5587210 EcE24377A_0852 Escherichia coli E24377A hypothetical protein YP_001461977.1 869719 R 331111 CDS YP_001461978.1 157155922 5589197 complement(870675..871916) 1 NC_009801.1 identified by match to protein family HMM PF00614; cardiolipin synthase 2 871916 5589197 EcE24377A_0853 Escherichia coli E24377A cardiolipin synthase 2 YP_001461978.1 870675 R 331111 CDS YP_001461979.1 157158462 5589570 871891..872010 1 NC_009801.1 identified by glimmer; hypothetical protein 872010 5589570 EcE24377A_0855 Escherichia coli E24377A hypothetical protein YP_001461979.1 871891 D 331111 CDS YP_001461980.1 157158045 5586571 complement(871913..872674) 1 NC_009801.1 identified by match to protein family HMM PF03372; hypothetical protein 872674 5586571 EcE24377A_0854 Escherichia coli E24377A hypothetical protein YP_001461980.1 871913 R 331111 CDS YP_001461981.1 157157548 5590630 872807..873217 1 NC_009801.1 hypothetical protein 873217 5590630 EcE24377A_0857 Escherichia coli E24377A hypothetical protein YP_001461981.1 872807 D 331111 CDS YP_001461982.1 157157012 5587926 complement(873179..874285) 1 NC_009801.1 identified by match to protein family HMM PF01061; ABC-2 type transporter permease 874285 5587926 EcE24377A_0856 Escherichia coli E24377A ABC-2 type transporter permease YP_001461982.1 873179 R 331111 CDS YP_001461983.1 157155290 5589289 complement(874296..875429) 1 NC_009801.1 identified by match to protein family HMM PF01061; ABC-2 type transporter permease 875429 5589289 EcE24377A_0858 Escherichia coli E24377A ABC-2 type transporter permease YP_001461983.1 874296 R 331111 CDS YP_001461984.1 157155843 5587273 complement(875422..877158) 1 NC_009801.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 877158 5587273 EcE24377A_0859 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001461984.1 875422 R 331111 CDS YP_001461985.1 157159083 5588954 complement(877151..878146) 1 NC_009801.1 identified by match to protein family HMM PF00529; hypothetical protein 878146 5588954 EcE24377A_0860 Escherichia coli E24377A hypothetical protein YP_001461985.1 877151 R 331111 CDS YP_001461986.1 157158577 5587991 complement(878149..878820) 1 NC_009801.1 identified by match to protein family HMM PF00440; match to protein family HMM PF09209; DNA-binding transcriptional regulator 878820 5587991 EcE24377A_0861 Escherichia coli E24377A DNA-binding transcriptional regulator YP_001461986.1 878149 R 331111 CDS YP_001461987.1 157155652 5588318 879049..880413 1 NC_009801.1 this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 880413 5588318 EcE24377A_0862 Escherichia coli E24377A ATP-dependent RNA helicase RhlE YP_001461987.1 879049 D 331111 CDS YP_001461988.1 157155114 5588120 complement(880418..880579) 1 NC_009801.1 identified by glimmer; hypothetical protein 880579 5588120 EcE24377A_0863 Escherichia coli E24377A hypothetical protein YP_001461988.1 880418 R 331111 CDS YP_001461989.1 157157723 5587679 880420..880515 1 NC_009801.1 identified by glimmer; hypothetical protein 880515 5587679 EcE24377A_0864 Escherichia coli E24377A hypothetical protein YP_001461989.1 880420 D 331111 CDS YP_001461990.1 157156047 5589394 complement(880645..881127) 1 NC_009801.1 identified by similarity to GB:CAD72180.1; match to protein family HMM PF08719; match to protein family HMM TIGR02464; hypothetical protein 881127 5589394 EcE24377A_0865 Escherichia coli E24377A hypothetical protein YP_001461990.1 880645 R 331111 CDS YP_001461991.1 157157572 5588821 881247..883397 1 NC_009801.1 helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 883397 dinG 5588821 dinG Escherichia coli E24377A ATP-dependent DNA helicase DinG YP_001461991.1 881247 D 331111 CDS YP_001461992.1 157158245 5590605 883425..884387 1 NC_009801.1 identified by match to protein family HMM PF02885; glycosyl transferase family protein 884387 5590605 EcE24377A_0867 Escherichia coli E24377A glycosyl transferase family protein YP_001461992.1 883425 D 331111 CDS YP_001461993.1 157154919 5590173 complement(884425..884529) 1 NC_009801.1 identified by glimmer; hypothetical protein 884529 5590173 EcE24377A_0868 Escherichia coli E24377A hypothetical protein YP_001461993.1 884425 R 331111 CDS YP_001461994.1 157158991 5588321 884528..885613 1 NC_009801.1 identified by similarity to PDB:2G8Y_A; match to protein family HMM PF02615; hypothetical protein 885613 5588321 EcE24377A_0869 Escherichia coli E24377A hypothetical protein YP_001461994.1 884528 D 331111 CDS YP_001461995.1 157156695 5590525 complement(885842..886102) 1 NC_009801.1 identified by match to protein family HMM PF07338; hypothetical protein 886102 5590525 EcE24377A_0870 Escherichia coli E24377A hypothetical protein YP_001461995.1 885842 R 331111 CDS YP_001461996.1 157156169 5588523 complement(886367..886633) 1 NC_009801.1 identified by match to protein family HMM PF01258; hypothetical protein 886633 5588523 EcE24377A_0871 Escherichia coli E24377A hypothetical protein YP_001461996.1 886367 R 331111 CDS YP_001461997.1 157158694 5589563 complement(886707..887384) 1 NC_009801.1 identified by match to protein family HMM PF03171; hydroxylase 887384 5589563 EcE24377A_0872 Escherichia coli E24377A hydroxylase YP_001461997.1 886707 R 331111 CDS YP_001461998.1 157158182 5589018 complement(887426..889708) 1 NC_009801.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu 889708 fiu 5589018 fiu Escherichia coli E24377A catecholate siderophore receptor Fiu YP_001461998.1 887426 R 331111 CDS YP_001461999.1 157159407 5590588 889692..889796 1 NC_009801.1 identified by glimmer; hypothetical protein 889796 5590588 EcE24377A_0874 Escherichia coli E24377A hypothetical protein YP_001461999.1 889692 D 331111 CDS YP_001462000.1 157158878 5588487 complement(889973..890377) 1 NC_009801.1 identified by match to protein family HMM PF07338; hypothetical protein 890377 5588487 EcE24377A_0875 Escherichia coli E24377A hypothetical protein YP_001462000.1 889973 R 331111 CDS YP_001462001.1 157155334 5588793 890428..891435 1 NC_009801.1 identified by match to protein family HMM PF05971; SAM-dependent methyltransferase 891435 5588793 EcE24377A_0877 Escherichia coli E24377A SAM-dependent methyltransferase YP_001462001.1 890428 D 331111 CDS YP_001462002.1 157154896 5588938 complement(891432..893657) 1 NC_009801.1 identified by match to protein family HMM PF00924; hypothetical protein 893657 5588938 EcE24377A_0876 Escherichia coli E24377A hypothetical protein YP_001462002.1 891432 R 331111 CDS YP_001462003.1 157157990 5588046 complement(893774..894496) 1 NC_009801.1 similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein 894496 glnQ 5588046 glnQ Escherichia coli E24377A glutamine ABC transporter ATP-binding protein YP_001462003.1 893774 R 331111 CDS YP_001462004.1 157157493 5586145 complement(894493..895152) 1 NC_009801.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease 895152 glnP 5586145 glnP Escherichia coli E24377A glutamine ABC transporter permease YP_001462004.1 894493 R 331111 CDS YP_001462005.1 157158136 5586697 complement(895291..896037) 1 NC_009801.1 similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein 896037 glnH 5586697 glnH Escherichia coli E24377A glutamine ABC transporter periplasmic protein YP_001462005.1 895291 R 331111 CDS YP_001462006.1 157157637 5588356 complement(896441..896944) 1 NC_009801.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 896944 dps 5588356 dps Escherichia coli E24377A DNA starvation/stationary phase protection protein Dps YP_001462006.1 896441 R 331111 CDS YP_001462007.1 157159238 5589800 complement(897114..897212) 1 NC_009801.1 identified by glimmer; hypothetical protein 897212 5589800 EcE24377A_0882 Escherichia coli E24377A hypothetical protein YP_001462007.1 897114 R 331111 CDS YP_001462008.1 157158672 5586559 complement(897243..898130) 1 NC_009801.1 identified by similarity to SP:P0AA67; match to protein family HMM PF00892; threonine and homoserine efflux system 898130 rhtA 5586559 rhtA Escherichia coli E24377A threonine and homoserine efflux system YP_001462008.1 897243 R 331111 CDS YP_001462009.1 157155407 5588532 898483..898998 1 NC_009801.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 898998 ompX 5588532 ompX Escherichia coli E24377A outer membrane protein X YP_001462009.1 898483 D 331111 CDS YP_001462010.1 157154892 5587604 complement(899047..900630) 1 NC_009801.1 identified by match to protein family HMM PF00884; sulfatase 900630 5587604 EcE24377A_0885 Escherichia coli E24377A sulfatase YP_001462010.1 899047 R 331111 CDS YP_001462011.1 157156503 5588217 complement(900902..901030) 1 NC_009801.1 hypothetical protein 901030 5588217 EcE24377A_0886 Escherichia coli E24377A hypothetical protein YP_001462011.1 900902 R 331111 CDS YP_001462012.1 157155992 5588343 901216..901683 1 NC_009801.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 901683 mntR 5588343 mntR Escherichia coli E24377A manganese transport regulator MntR YP_001462012.1 901216 D 331111 CDS YP_001462013.1 157157541 5587868 901680..902798 1 NC_009801.1 identified by match to protein family HMM PF03600; citrate transporter family protein 902798 5587868 EcE24377A_0888 Escherichia coli E24377A citrate transporter family protein YP_001462013.1 901680 D 331111 CDS YP_001462014.1 157159386 5588180 complement(902857..903777) 1 NC_009801.1 identified by similarity to SP:P0AAX8; match to protein family HMM PF03734; hypothetical protein 903777 ybiS 5588180 ybiS Escherichia coli E24377A hypothetical protein YP_001462014.1 902857 R 331111 CDS YP_001462015.1 157156320 5588690 903996..905588 1 NC_009801.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 905588 5588690 EcE24377A_0890 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001462015.1 903996 D 331111 CDS YP_001462016.1 157156822 5588267 905867..906847 1 NC_009801.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 906847 5588267 EcE24377A_0891 Escherichia coli E24377A IS621, transposase YP_001462016.1 905867 D 331111 CDS YP_001462017.1 157157592 5586585 complement(907108..908373) 1 NC_009801.1 identified by match to protein family HMM PF07350; hypothetical protein 908373 5586585 EcE24377A_0892 Escherichia coli E24377A hypothetical protein YP_001462017.1 907108 R 331111 CDS YP_001462018.1 157158127 5588841 complement(908525..909340) 1 NC_009801.1 identified by similarity to SP:P75792; match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; sugar phosphatase SupH 909340 supH 5588841 supH Escherichia coli E24377A sugar phosphatase SupH YP_001462018.1 908525 R 331111 CDS YP_001462019.1 157155776 5586411 complement(909486..911918) 1 NC_009801.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774; formate C-acetyltransferas 911918 5586411 EcE24377A_0894 Escherichia coli E24377A formate C-acetyltransferas YP_001462019.1 909486 R 331111 CDS YP_001462020.1 157158814 5590306 complement(911924..912823) 1 NC_009801.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494; glycyl-radical activating family protein 912823 5590306 EcE24377A_0895 Escherichia coli E24377A glycyl-radical activating family protein YP_001462020.1 911924 R 331111 CDS YP_001462021.1 157154751 5587730 912954..913616 1 NC_009801.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 913616 fsaA 5587730 fsaA Escherichia coli E24377A fructose-6-phosphate aldolase YP_001462021.1 912954 D 331111 CDS YP_001462022.1 157155396 5587226 complement(913795..914544) 1 NC_009801.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 914544 moeB 5587226 moeB Escherichia coli E24377A molybdopterin biosynthesis protein MoeB YP_001462022.1 913795 R 331111 CDS YP_001462023.1 157157979 5588583 complement(914544..915779) 1 NC_009801.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA 915779 moeA 5588583 moeA Escherichia coli E24377A molybdopterin biosynthesis protein MoeA YP_001462023.1 914544 R 331111 CDS YP_001462024.1 157155936 5590459 915983..916948 1 NC_009801.1 identified by similarity to SP:P37595; match to protein family HMM PF01112; L-asparaginase 916948 5590459 EcE24377A_0899 Escherichia coli E24377A L-asparaginase YP_001462024.1 915983 D 331111 CDS YP_001462025.1 157157502 5588302 916935..918806 1 NC_009801.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 918806 gsiA 5588302 gsiA Escherichia coli E24377A glutathione transporter ATP-binding protein YP_001462025.1 916935 D 331111 CDS YP_001462026.1 157155455 5588440 918826..920364 1 NC_009801.1 identified by similarity to SP:P75797; match to protein family HMM PF00496; glutathione ABC transporter periplasmic glutathione-binding protein GsiB 920364 gsiB 5588440 gsiB Escherichia coli E24377A glutathione ABC transporter periplasmic glutathione-binding protein GsiB YP_001462026.1 918826 D 331111 CDS YP_001462027.1 157158547 5588866 920382..921302 1 NC_009801.1 identified by similarity to SP:P75798; match to protein family HMM PF00528; glutathione ABC transporter permease GsiC 921302 gsiC 5588866 gsiC Escherichia coli E24377A glutathione ABC transporter permease GsiC YP_001462027.1 920382 D 331111 CDS YP_001462028.1 157155998 5588830 921305..922216 1 NC_009801.1 identified by similarity to SP:P75799; match to protein family HMM PF00528; glutathione ABC transporter permease GsiD 922216 gsiD 5588830 gsiD Escherichia coli E24377A glutathione ABC transporter permease GsiD YP_001462028.1 921305 D 331111 CDS YP_001462029.1 157156658 5588903 922394..924742 1 NC_009801.1 identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase domain-containing protein 924742 5588903 EcE24377A_0904 Escherichia coli E24377A cyclic diguanylate phosphodiesterase domain-containing protein YP_001462029.1 922394 D 331111 CDS YP_001462030.1 157158156 5590110 924750..926078 1 NC_009801.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 926078 5590110 EcE24377A_0905 Escherichia coli E24377A diguanylate cyclase YP_001462030.1 924750 D 331111 CDS YP_001462031.1 157156507 5586515 complement(926125..927450) 1 NC_009801.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 927450 rimO 5586515 rimO Escherichia coli E24377A ribosomal protein S12 methylthiotransferase YP_001462031.1 926125 R 331111 CDS YP_001462032.1 157158184 5590433 927630..928046 1 NC_009801.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 928046 bssR 5590433 bssR Escherichia coli E24377A biofilm formation regulatory protein BssR YP_001462032.1 927630 D 331111 CDS YP_001462033.1 157157686 5590590 928157..929272 1 NC_009801.1 identified by similarity to SP:P75804; match to protein family HMM PF07995; aldose sugar dehydrogenase yliI 929272 yliI 5590590 yliI Escherichia coli E24377A aldose sugar dehydrogenase yliI YP_001462033.1 928157 D 331111 CDS YP_001462034.1 157158559 5587964 complement(929269..929895) 1 NC_009801.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase 929895 5587964 EcE24377A_0908 Escherichia coli E24377A glutathione S-transferase YP_001462034.1 929269 R 331111 CDS YP_001462035.1 157157612 5589168 930142..931344 1 NC_009801.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 931344 dacC 5589168 dacC Escherichia coli E24377A D-alanyl-D-alanine carboxypeptidase YP_001462035.1 930142 D 331111 CDS YP_001462036.1 157155465 5590668 complement(931391..932149) 1 NC_009801.1 identified by similarity to SP:P0ACK5; match to protein family HMM PF00455; match to protein family HMM PF08220; DNA-binding transcriptional repressor DeoR 932149 deoR 5590668 deoR Escherichia coli E24377A DNA-binding transcriptional repressor DeoR YP_001462036.1 931391 R 331111 CDS YP_001462037.1 157156156 5588876 complement(932207..932803) 1 NC_009801.1 identified by match to protein family HMM PF01569; undecaprenyl pyrophosphate phosphatase 932803 5588876 EcE24377A_0912 Escherichia coli E24377A undecaprenyl pyrophosphate phosphatase YP_001462037.1 932207 R 331111 CDS YP_001462038.1 157158643 5586030 932996..933103 1 NC_009801.1 identified by glimmer; hypothetical protein 933103 5586030 EcE24377A_0913 Escherichia coli E24377A hypothetical protein YP_001462038.1 932996 D 331111 CDS YP_001462039.1 157159279 5588247 933088..934320 1 NC_009801.1 identified by match to protein family HMM PF07690; multidrug translocase MdfA 934320 mdfA 5588247 mdfA Escherichia coli E24377A multidrug translocase MdfA YP_001462039.1 933088 D 331111 CDS YP_001462040.1 157157457 5587537 complement(934360..934638) 1 NC_009801.1 hypothetical protein 934638 5587537 EcE24377A_0915 Escherichia coli E24377A hypothetical protein YP_001462040.1 934360 R 331111 CDS YP_001462041.1 157158163 5586294 complement(934730..935545) 1 NC_009801.1 identified by similarity to SP:P75809; match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; phosphatase YbjI 935545 ybjI 5586294 ybjI Escherichia coli E24377A phosphatase YbjI YP_001462041.1 934730 R 331111 CDS YP_001462042.1 157157623 5587816 complement(935545..936753) 1 NC_009801.1 identified by match to protein family HMM PF07690; major facilitator transporter 936753 5587816 EcE24377A_0917 Escherichia coli E24377A major facilitator transporter YP_001462042.1 935545 R 331111 CDS YP_001462043.1 157158161 5586795 936837..937373 1 NC_009801.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 937373 5586795 EcE24377A_0918 Escherichia coli E24377A TetR family transcriptional regulator YP_001462043.1 936837 D 331111 CDS YP_001462044.1 157156043 5585972 complement(937548..939233) 1 NC_009801.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625; hypothetical protein 939233 5585972 EcE24377A_0919 Escherichia coli E24377A hypothetical protein YP_001462044.1 937548 R 331111 CDS YP_001462045.1 157157779 5586040 939503..939880 1 NC_009801.1 hypothetical protein 939880 5586040 EcE24377A_0920 Escherichia coli E24377A hypothetical protein YP_001462045.1 939503 D 331111 CDS YP_001462046.1 157156488 5586965 complement(939910..940167) 1 NC_009801.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 940167 grxA 5586965 grxA Escherichia coli E24377A glutaredoxin YP_001462046.1 939910 R 331111 CDS YP_001462047.1 157156891 5589250 940327..940614 1 NC_009801.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 940614 5589250 EcE24377A_0922 Escherichia coli E24377A hypothetical protein YP_001462047.1 940327 D 331111 CDS YP_001462048.1 157157162 5589926 940598..941320 1 NC_009801.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 941320 nfsA 5589926 nfsA Escherichia coli E24377A nitroreductase A YP_001462048.1 940598 D 331111 CDS YP_001462049.1 157157767 5588152 941381..942283 1 NC_009801.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 942283 rimK 5588152 rimK Escherichia coli E24377A ribosomal protein S6 modification protein YP_001462049.1 941381 D 331111 CDS YP_001462050.1 157156403 5590228 942323..942847 1 NC_009801.1 hypothetical protein 942847 5590228 EcE24377A_0925 Escherichia coli E24377A hypothetical protein YP_001462050.1 942323 D 331111 CDS YP_001462051.1 157157062 5586117 943198..944310 1 NC_009801.1 identified by match to protein family HMM PF01547; putrescine ABC transporter periplasmic-binding protein 944310 potF 5586117 potF Escherichia coli E24377A putrescine ABC transporter periplasmic-binding protein YP_001462051.1 943198 D 331111 CDS YP_001462052.1 157159442 5585978 944405..945538 1 NC_009801.1 part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 945538 potG 5585978 potG Escherichia coli E24377A putrescine ABC transporter ATP-binding protein YP_001462052.1 944405 D 331111 CDS YP_001462053.1 157155423 5587009 945548..946501 1 NC_009801.1 identified by match to protein family HMM PF00528; putrescine ABC transporter membrane protein 946501 potH 5587009 potH Escherichia coli E24377A putrescine ABC transporter membrane protein YP_001462053.1 945548 D 331111 CDS YP_001462054.1 157158340 5588344 946498..947343 1 NC_009801.1 identified by match to protein family HMM PF00528; putrescine ABC transporter membrane protein 947343 potI 5588344 potI Escherichia coli E24377A putrescine ABC transporter membrane protein YP_001462054.1 946498 D 331111 CDS YP_001462055.1 157159342 5590468 947403..947891 1 NC_009801.1 hypothetical protein 947891 5590468 EcE24377A_0930 Escherichia coli E24377A hypothetical protein YP_001462055.1 947403 D 331111 CDS YP_001462056.1 157156456 5587143 947932..949059 1 NC_009801.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 949059 rumB 5587143 rumB Escherichia coli E24377A 23S rRNA methyluridine methyltransferase YP_001462056.1 947932 D 331111 CDS YP_001462057.1 157155686 5589317 949071..949259 1 NC_009801.1 identified by glimmer; hypothetical protein 949259 5589317 EcE24377A_0933 Escherichia coli E24377A hypothetical protein YP_001462057.1 949071 D 331111 CDS YP_001462058.1 157155628 5589222 complement(949234..949965) 1 NC_009801.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096; arginine ABC transporter substrate-binding protein 949965 artJ 5589222 artJ Escherichia coli E24377A arginine ABC transporter substrate-binding protein YP_001462058.1 949234 R 331111 CDS YP_001462059.1 157155015 5585966 complement(950256..950924) 1 NC_009801.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 950924 artM 5585966 artM Escherichia coli E24377A arginine transporter permease subunit ArtM YP_001462059.1 950256 R 331111 CDS YP_001462060.1 157157070 5588745 complement(950924..951640) 1 NC_009801.1 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 951640 artQ 5588745 artQ Escherichia coli E24377A arginine transporter permease subunit ArtQ YP_001462060.1 950924 R 331111 CDS YP_001462061.1 157156637 5588428 complement(951647..952378) 1 NC_009801.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096; arginine ABC transporter substrate-binding protein 952378 artI 5588428 artI Escherichia coli E24377A arginine ABC transporter substrate-binding protein YP_001462061.1 951647 R 331111 CDS YP_001462062.1 157157968 5587245 complement(952396..953124) 1 NC_009801.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 953124 artP 5587245 artP Escherichia coli E24377A arginine transporter ATP-binding subunit YP_001462062.1 952396 R 331111 CDS YP_001462063.1 157157231 5589605 complement(953342..953857) 1 NC_009801.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein 953857 5589605 EcE24377A_0938 Escherichia coli E24377A lipoprotein YP_001462063.1 953342 R 331111 CDS YP_001462064.1 157159319 5586415 953983..954306 1 NC_009801.1 identified by match to protein family HMM PF01906; hypothetical protein 954306 5586415 EcE24377A_0939 Escherichia coli E24377A hypothetical protein YP_001462064.1 953983 D 331111 CDS YP_001462065.1 157156326 5588928 954303..955133 1 NC_009801.1 identified by similarity to SP:P75820; match to protein family HMM PF01510; N-acetylmuramoyl-L-alanine amidase 955133 amiD 5588928 amiD Escherichia coli E24377A N-acetylmuramoyl-L-alanine amidase YP_001462065.1 954303 D 331111 CDS YP_001462066.1 157155941 5589963 complement(955130..956179) 1 NC_009801.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993; NAD-dependent epimerase/dehydratase 956179 5589963 EcE24377A_0940 Escherichia coli E24377A NAD-dependent epimerase/dehydratase YP_001462066.1 955130 R 331111 CDS YP_001462067.1 157156770 5588708 complement(956242..957672) 1 NC_009801.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF05368; NAD dependent epimerase/dehydratase 957672 5588708 EcE24377A_0942 Escherichia coli E24377A NAD dependent epimerase/dehydratase YP_001462067.1 956242 R 331111 CDS YP_001462068.1 157157460 5588622 complement(957683..958684) 1 NC_009801.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase 958684 ltaE 5588622 ltaE Escherichia coli E24377A L-threonine aldolase YP_001462068.1 957683 R 331111 CDS YP_001462069.1 157158121 5588123 complement(958721..960439) 1 NC_009801.1 catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 960439 poxB 5588123 poxB Escherichia coli E24377A pyruvate dehydrogenase YP_001462069.1 958721 R 331111 CDS YP_001462070.1 157158757 5590111 complement(960572..961540) 1 NC_009801.1 identified by similarity to SP:P75824; match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; HCP oxidoreductase 961540 hcr 5590111 hcr Escherichia coli E24377A HCP oxidoreductase YP_001462070.1 960572 R 331111 CDS YP_001462071.1 157159413 5586715 complement(961552..963204) 1 NC_009801.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 963204 hcp 5586715 hcp Escherichia coli E24377A hydroxylamine reductase YP_001462071.1 961552 R 331111 CDS YP_001462072.1 157155577 5586130 complement(963348..964247) 1 NC_009801.1 identified by match to protein family HMM PF03956; hypothetical protein 964247 5586130 EcE24377A_0947 Escherichia coli E24377A hypothetical protein YP_001462072.1 963348 R 331111 CDS YP_001462073.1 157156179 5586768 complement(964704..965399) 1 NC_009801.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 965399 aqpZ 5586768 aqpZ Escherichia coli E24377A aquaporin Z YP_001462073.1 964704 R 331111 CDS YP_001462074.1 157157472 5589258 965825..967483 1 NC_009801.1 identified by similarity to GB:ABG68906.1; hypothetical protein 967483 5589258 EcE24377A_0950 Escherichia coli E24377A hypothetical protein YP_001462074.1 965825 D 331111 CDS YP_001462075.1 157155099 5586473 complement(967480..968472) 1 NC_009801.1 identified by match to protein family HMM PF04393; hypothetical protein 968472 5586473 EcE24377A_0949 Escherichia coli E24377A hypothetical protein YP_001462075.1 967480 R 331111 CDS YP_001462076.1 157157920 5588375 968587..969702 1 NC_009801.1 confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 969702 macA 5588375 macA Escherichia coli E24377A macrolide transporter subunit MacA YP_001462076.1 968587 D 331111 CDS YP_001462077.1 157156996 5588087 complement(971717..971941) 1 NC_009801.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD 971941 cspD 5588087 cspD Escherichia coli E24377A stationary phase/starvation inducible regulatory protein CspD YP_001462077.1 971717 R 331111 CDS YP_001462078.1 157156472 5590482 972264..972584 1 NC_009801.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 972584 clpS 5590482 clpS Escherichia coli E24377A ATP-dependent Clp protease adaptor protein ClpS YP_001462078.1 972264 D 331111 CDS YP_001462079.1 157159066 5589455 972615..974891 1 NC_009801.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 974891 clpA 5589455 clpA Escherichia coli E24377A ATP-dependent Clp protease ATP-binding subunit YP_001462079.1 972615 D 331111 CDS YP_001462080.1 157158572 5589052 complement(975635..975853) 1 NC_009801.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 975853 infA 5589052 infA Escherichia coli E24377A translation initiation factor IF-1 YP_001462080.1 975635 R 331111 CDS YP_001462081.1 157157751 5586913 complement(976138..976842) 1 NC_009801.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 976842 aat 5586913 aat Escherichia coli E24377A leucyl/phenylalanyl-tRNA--protein transferase YP_001462081.1 976138 R 331111 CDS YP_001462082.1 157154940 5587184 complement(976884..978605) 1 NC_009801.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 978605 cudC 5587184 cudC Escherichia coli E24377A cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_001462082.1 976884 R 331111 CDS YP_001462083.1 157157863 5586360 complement(978606..980372) 1 NC_009801.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 980372 cydD 5586360 cydD Escherichia coli E24377A cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_001462083.1 978606 R 331111 CDS YP_001462084.1 157158398 5586186 979169..979261 1 NC_009801.1 identified by glimmer; hypothetical protein 979261 5586186 EcE24377A_0961 Escherichia coli E24377A hypothetical protein YP_001462084.1 979169 D 331111 CDS YP_001462085.1 157155789 5590238 complement(980495..981460) 1 NC_009801.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase 981460 trxB 5590238 trxB Escherichia coli E24377A thioredoxin reductase YP_001462085.1 980495 R 331111 CDS YP_001462086.1 157156029 5587632 981529..981642 1 NC_009801.1 identified by glimmer; hypothetical protein 981642 5587632 EcE24377A_0963 Escherichia coli E24377A hypothetical protein YP_001462086.1 981529 D 331111 CDS YP_001462087.1 157159036 5587257 982005..982499 1 NC_009801.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 982499 lrp 5587257 lrp Escherichia coli E24377A leucine-responsive transcriptional regulator YP_001462087.1 982005 D 331111 CDS YP_001462088.1 157154961 5587947 982634..986740 1 NC_009801.1 DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 986740 ftsK 5587947 ftsK Escherichia coli E24377A DNA translocase FtsK YP_001462088.1 982634 D 331111 CDS YP_001462089.1 157158652 5588933 986895..987506 1 NC_009801.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 987506 lolA 5588933 lolA Escherichia coli E24377A outer-membrane lipoprotein carrier protein YP_001462089.1 986895 D 331111 CDS YP_001462090.1 157159331 5589371 987517..988860 1 NC_009801.1 identified by similarity to SP:P0AAZ4; match to protein family HMM PF00004; recombination factor protein RarA 988860 5589371 EcE24377A_0967 Escherichia coli E24377A recombination factor protein RarA YP_001462090.1 987517 D 331111 CDS YP_001462091.1 157157556 5590561 988951..990243 1 NC_009801.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 990243 serS 5590561 serS Escherichia coli E24377A seryl-tRNA synthetase YP_001462091.1 988951 D 331111 CDS YP_001462092.1 157157252 5589261 990482..992926 1 NC_009801.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166; anaerobic dimethyl sulfoxide reductase, A subunit 992926 dmsA 5589261 dmsA Escherichia coli E24377A anaerobic dimethyl sulfoxide reductase, A subunit YP_001462092.1 990482 D 331111 CDS YP_001462093.1 157158279 5588724 992937..993554 1 NC_009801.1 identified by similarity to SP:P18776; match to protein family HMM PF00037; match to protein family HMM TIGR02951; dimethylsulfoxide reductase subunit B 993554 dmsB1 5588724 dmsB1 Escherichia coli E24377A dimethylsulfoxide reductase subunit B YP_001462093.1 992937 D 331111 CDS YP_001462094.1 157156328 5588204 complement(993132..994037) 1 NC_009801.1 identified by glimmer; hypothetical protein 994037 5588204 EcE24377A_0970 Escherichia coli E24377A hypothetical protein YP_001462094.1 993132 R 331111 CDS YP_001462095.1 157158738 5590818 993556..994419 1 NC_009801.1 identified by similarity to SP:P18777; match to protein family HMM PF04976; anaerobic dimethyl sulfoxide reductase subunit C 994419 dmsC1 5590818 dmsC1 Escherichia coli E24377A anaerobic dimethyl sulfoxide reductase subunit C YP_001462095.1 993556 D 331111 CDS YP_001462096.1 157155842 5589640 complement(994455..995081) 1 NC_009801.1 identified by match to protein family HMM PF00857; isochorismatase hydrolase 995081 5589640 EcE24377A_0973 Escherichia coli E24377A isochorismatase hydrolase YP_001462096.1 994455 R 331111 CDS YP_001462097.1 157157127 5588953 complement(995237..995365) 1 NC_009801.1 identified by glimmer; hypothetical protein 995365 5588953 EcE24377A_0974 Escherichia coli E24377A hypothetical protein YP_001462097.1 995237 R 331111 CDS YP_001462098.1 157158970 5586123 995396..996544 1 NC_009801.1 identified by match to protein family HMM PF07690; MFS family transporter protein 996544 5586123 EcE24377A_0975 Escherichia coli E24377A MFS family transporter protein YP_001462098.1 995396 D 331111 CDS YP_001462099.1 157156107 5589918 996562..998184 1 NC_009801.1 identified by match to protein family HMM PF00324; amino acid permease 998184 5589918 EcE24377A_0976 Escherichia coli E24377A amino acid permease YP_001462099.1 996562 D 331111 CDS YP_001462100.1 157157918 5589865 complement(998185..999093) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 999093 5589865 EcE24377A_0977 Escherichia coli E24377A LysR family transcriptional regulator YP_001462100.1 998185 R 331111 CDS YP_001462101.1 157156857 5588495 998188..998301 1 NC_009801.1 identified by glimmer; hypothetical protein 998301 5588495 EcE24377A_0978 Escherichia coli E24377A hypothetical protein YP_001462101.1 998188 D 331111 CDS YP_001462102.1 157156835 5588567 999193..999783 1 NC_009801.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358; hypothetical protein 999783 5588567 EcE24377A_0979 Escherichia coli E24377A hypothetical protein YP_001462102.1 999193 D 331111 CDS YP_001462103.1 157154815 5586370 complement(999865..1000662) 1 NC_009801.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 1000662 pflA 5586370 pflA Escherichia coli E24377A pyruvate formate lyase-activating enzyme 1 YP_001462103.1 999865 R 331111 CDS YP_001462104.1 157155436 5587204 complement(1000694..1001689) 1 NC_009801.1 identified by match to protein family HMM PF00589; phage integrase site specific recombinase 1001689 5587204 EcE24377A_0981 Escherichia coli E24377A phage integrase site specific recombinase YP_001462104.1 1000694 R 331111 CDS YP_001462105.1 157158810 5590852 1002191..1002547 1 NC_009801.1 identified by similarity to SP:P07695; phage regulatory protein 1002547 cox 5590852 cox Escherichia coli E24377A phage regulatory protein YP_001462105.1 1002191 D 331111 CDS YP_001462106.1 157157120 5588896 1002725..1003225 1 NC_009801.1 identified by similarity to SP:P07696; replication gene B protein 1003225 5588896 EcE24377A_0983 Escherichia coli E24377A replication gene B protein YP_001462106.1 1002725 D 331111 CDS YP_001462107.1 157157544 5589842 1003256..1003513 1 NC_009801.1 identified by similarity to GB:AAL21618.1; hypothetical protein 1003513 5589842 EcE24377A_0984 Escherichia coli E24377A hypothetical protein YP_001462107.1 1003256 D 331111 CDS YP_001462108.1 157158091 5587472 1003513..1003815 1 NC_009801.1 hypothetical protein 1003815 5587472 EcE24377A_0985 Escherichia coli E24377A hypothetical protein YP_001462108.1 1003513 D 331111 CDS YP_001462109.1 157156801 5586233 1003815..1004039 1 NC_009801.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02419; C4-type zinc finger DksA/TraR family protein 1004039 5586233 EcE24377A_0986 Escherichia coli E24377A C4-type zinc finger DksA/TraR family protein YP_001462109.1 1003815 D 331111 CDS YP_001462110.1 157155433 5587715 1004036..1004311 1 NC_009801.1 hypothetical protein 1004311 5587715 EcE24377A_0987 Escherichia coli E24377A hypothetical protein YP_001462110.1 1004036 D 331111 CDS YP_001462111.1 157159033 5587824 1004301..1006577 1 NC_009801.1 identified by similarity to SP:Q06419; match to protein family HMM PF05840; replication gene A protein 1006577 gpA 5587824 gpA Escherichia coli E24377A replication gene A protein YP_001462111.1 1004301 D 331111 CDS YP_001462112.1 157154774 5589308 1007691..1008992 1 NC_009801.1 identified by similarity to GB:ABB41600.1; hypothetical protein 1008992 5589308 EcE24377A_0989 Escherichia coli E24377A hypothetical protein YP_001462112.1 1007691 D 331111 CDS YP_001462113.1 157155636 5588667 complement(1009542..1010084) 1 NC_009801.1 identified by match to protein family HMM PF04860; PBSX family phage portal protein 1010084 5588667 EcE24377A_0990 Escherichia coli E24377A PBSX family phage portal protein YP_001462113.1 1009542 R 331111 CDS YP_001462114.1 157157895 5588914 1010333..1011418 1 NC_009801.1 hypothetical protein 1011418 5588914 EcE24377A_0993 Escherichia coli E24377A hypothetical protein YP_001462114.1 1010333 D 331111 CDS YP_001462115.1 157157180 5587491 1011492..1012664 1 NC_009801.1 identified by similarity to SP:P15025; match to protein family HMM PF00665; IS21 family transposase 1012664 5587491 EcE24377A_0994 Escherichia coli E24377A IS21 family transposase YP_001462115.1 1011492 D 331111 CDS YP_001462116.1 157158879 5590535 1012664..1013458 1 NC_009801.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein 1013458 5590535 EcE24377A_0995 Escherichia coli E24377A IS21 family transposition helper protein YP_001462116.1 1012664 D 331111 CDS YP_001462117.1 157158449 5588794 1013530..1014909 1 NC_009801.1 hypothetical protein 1014909 5588794 EcE24377A_0996 Escherichia coli E24377A hypothetical protein YP_001462117.1 1013530 D 331111 CDS YP_001462118.1 157158387 5586765 1014924..1015403 1 NC_009801.1 identified by match to protein family HMM PF06995; phage protein gpU 1015403 gpU 5586765 gpU Escherichia coli E24377A phage protein gpU YP_001462118.1 1014924 D 331111 CDS YP_001462119.1 157155788 5590337 1015403..1016566 1 NC_009801.1 identified by match to protein family HMM PF05954; phage late control gene D protein 1016566 5590337 EcE24377A_0998 Escherichia coli E24377A phage late control gene D protein YP_001462119.1 1015403 D 331111 CDS YP_001462120.1 157155260 5587631 1016648..1016866 1 NC_009801.1 in E. coli K-12 this is in prophage P2 remnant; DNA-binding transcriptional regulator 1016866 5587631 EcE24377A_0999 Escherichia coli E24377A DNA-binding transcriptional regulator YP_001462120.1 1016648 D 331111 CDS YP_001462121.1 157157380 5590867 complement(1017186..1019468) 1 NC_009801.1 identified by similarity to SP:P09373; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; formate acetyltransferase 1019468 pflB2 5590867 pflB2 Escherichia coli E24377A formate acetyltransferase YP_001462121.1 1017186 R 331111 CDS YP_001462122.1 157156279 5590721 complement(1019523..1020380) 1 NC_009801.1 identified by match to protein family HMM PF01226; match to protein family HMM TIGR00790; formate transporter 1020380 5590721 EcE24377A_1001 Escherichia coli E24377A formate transporter YP_001462122.1 1019523 R 331111 CDS YP_001462123.1 157155234 5590752 complement(1020786..1022546) 1 NC_009801.1 identified by similarity to GB:AAP16417.1; match to protein family HMM PF02624; match to protein family HMM TIGR00702; hypothetical protein 1022546 5590752 EcE24377A_1002 Escherichia coli E24377A hypothetical protein YP_001462123.1 1020786 R 331111 CDS YP_001462124.1 157158882 5589043 1022676..1023368 1 NC_009801.1 identified by match to protein family HMM PF04239; hypothetical protein 1023368 5589043 EcE24377A_1003 Escherichia coli E24377A hypothetical protein YP_001462124.1 1022676 D 331111 CDS YP_001462125.1 157156276 5588588 1023567..1024655 1 NC_009801.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1024655 serC 5588588 serC Escherichia coli E24377A phosphoserine aminotransferase YP_001462125.1 1023567 D 331111 CDS YP_001462126.1 157155708 5590603 1024726..1026009 1 NC_009801.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1026009 aroA 5590603 aroA Escherichia coli E24377A 3-phosphoshikimate 1-carboxyvinyltransferase YP_001462126.1 1024726 D 331111 CDS YP_001462127.1 157157894 5588988 1026178..1026942 1 NC_009801.1 ycaL; identified by match to protein family HMM PF01435; M48B family peptidase 1026942 5588988 EcE24377A_1006 Escherichia coli E24377A M48B family peptidase YP_001462127.1 1026178 D 331111 CDS YP_001462128.1 157158043 5587490 1027115..1027798 1 NC_009801.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1027798 cmk 5587490 cmk Escherichia coli E24377A cytidylate kinase YP_001462128.1 1027115 D 331111 CDS YP_001462129.1 157156817 5589647 1027909..1029582 1 NC_009801.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1029582 rpsA 5589647 rpsA Escherichia coli E24377A 30S ribosomal protein S1 YP_001462129.1 1027909 D 331111 CDS YP_001462130.1 157157201 5586580 1029742..1030026 1 NC_009801.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1030026 ihfB 5586580 ihfB Escherichia coli E24377A integration host factor subunit beta YP_001462130.1 1029742 D 331111 CDS YP_001462131.1 157155375 5587004 1030233..1032497 1 NC_009801.1 ycaI; identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361; hypothetical protein 1032497 5587004 EcE24377A_1011 Escherichia coli E24377A hypothetical protein YP_001462131.1 1030233 D 331111 CDS YP_001462132.1 157158843 5586862 1032534..1034282 1 NC_009801.1 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding protein/permease 1034282 msbA 5586862 msbA Escherichia coli E24377A lipid transporter ATP-binding protein/permease YP_001462132.1 1032534 D 331111 CDS YP_001462133.1 157159401 5589730 1034279..1035265 1 NC_009801.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1035265 lpxK 5589730 lpxK Escherichia coli E24377A tetraacyldisaccharide 4'-kinase YP_001462133.1 1034279 D 331111 CDS YP_001462134.1 157155129 5586525 1035302..1036534 1 NC_009801.1 identified by match to protein family HMM PF06224; hypothetical protein 1036534 5586525 EcE24377A_1014 Escherichia coli E24377A hypothetical protein YP_001462134.1 1035302 D 331111 CDS YP_001462135.1 157155881 5586854 1036586..1036768 1 NC_009801.1 identified by similarity to GB:AAX64850.1; match to protein family HMM PF03966; hypothetical protein 1036768 5586854 EcE24377A_1015 Escherichia coli E24377A hypothetical protein YP_001462135.1 1036586 D 331111 CDS YP_001462136.1 157158835 5587158 1036765..1037511 1 NC_009801.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1037511 kdsB 5587158 kdsB Escherichia coli E24377A 3-deoxy-manno-octulosonate cytidylyltransferase YP_001462136.1 1036765 D 331111 CDS YP_001462137.1 157159198 5585916 1037665..1038558 1 NC_009801.1 hypothetical protein 1038558 5585916 EcE24377A_1018 Escherichia coli E24377A hypothetical protein YP_001462137.1 1037665 D 331111 CDS YP_001462138.1 157155611 5589433 complement(1038535..1039314) 1 NC_009801.1 identified by match to protein family HMM PF02698; hypothetical protein 1039314 5589433 EcE24377A_1017 Escherichia coli E24377A hypothetical protein YP_001462138.1 1038535 R 331111 CDS YP_001462139.1 157154950 5587042 complement(1039217..1039381) 1 NC_009801.1 identified by glimmer; hypothetical protein 1039381 5587042 EcE24377A_1019 Escherichia coli E24377A hypothetical protein YP_001462139.1 1039217 R 331111 CDS YP_001462140.1 157157799 5589485 1039450..1040235 1 NC_009801.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 1040235 smtA 5589485 smtA Escherichia coli E24377A metallothionein SmtA YP_001462140.1 1039450 D 331111 CDS YP_001462141.1 157158323 5589622 1040232..1041554 1 NC_009801.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1041554 mukF 5589622 mukF Escherichia coli E24377A condesin subunit F YP_001462141.1 1040232 D 331111 CDS YP_001462142.1 157158529 5588327 1041535..1042239 1 NC_009801.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1042239 mukE 5588327 mukE Escherichia coli E24377A condesin subunit E YP_001462142.1 1041535 D 331111 CDS YP_001462143.1 157159030 5587518 1042239..1046699 1 NC_009801.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1046699 mukB 5587518 mukB Escherichia coli E24377A cell division protein MukB YP_001462143.1 1042239 D 331111 CDS YP_001462144.1 157157051 5587766 1046960..1048807 1 NC_009801.1 identified by match to protein family HMM PF01471; hypothetical protein 1048807 5587766 EcE24377A_1024 Escherichia coli E24377A hypothetical protein YP_001462144.1 1046960 D 331111 CDS YP_001462145.1 157156554 5587304 1048988..1049536 1 NC_009801.1 identified by match to protein family HMM PF05951; match to protein family HMM PF08291; match to protein family HMM TIGR01409; Tat pathway signal sequence domain-containing protein 1049536 5587304 EcE24377A_1025 Escherichia coli E24377A Tat pathway signal sequence domain-containing protein YP_001462145.1 1048988 D 331111 CDS YP_001462146.1 157156504 5587720 1049563..1050210 1 NC_009801.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase 1050210 5587720 EcE24377A_1026 Escherichia coli E24377A metallo-beta-lactamase YP_001462146.1 1049563 D 331111 CDS YP_001462147.1 157156651 5588139 complement(1050432..1051622) 1 NC_009801.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 1051622 aspC 5588139 aspC Escherichia coli E24377A aromatic amino acid aminotransferase YP_001462147.1 1050432 R 331111 CDS YP_001462148.1 157156094 5589387 complement(1051696..1051794) 1 NC_009801.1 identified by glimmer; hypothetical protein 1051794 5589387 EcE24377A_1028 Escherichia coli E24377A hypothetical protein YP_001462148.1 1051696 R 331111 CDS YP_001462149.1 157158264 5586595 complement(1051807..1052895) 1 NC_009801.1 outer membrane porin F; 1a; Ia; b; outer membrane protein F 1052895 ompF 5586595 ompF Escherichia coli E24377A outer membrane protein F YP_001462149.1 1051807 R 331111 CDS YP_001462150.1 157157150 5587779 complement(1053497..1054897) 1 NC_009801.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1054897 asnC 5587779 asnC Escherichia coli E24377A asparaginyl-tRNA synthetase YP_001462150.1 1053497 R 331111 CDS YP_001462151.1 157159189 5588986 complement(1055066..1056268) 1 NC_009801.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1056268 pncB 5588986 pncB Escherichia coli E24377A nicotinate phosphoribosyltransferase YP_001462151.1 1055066 R 331111 CDS YP_001462152.1 157155731 5586539 1056534..1059146 1 NC_009801.1 identified by match to protein family HMM PF01433; match to protein family HMM TIGR02414; aminopeptidase 1059146 pepN 5586539 pepN Escherichia coli E24377A aminopeptidase YP_001462152.1 1056534 D 331111 CDS YP_001462153.1 157156013 5590194 1059162..1059278 1 NC_009801.1 identified by glimmer; hypothetical protein 1059278 5590194 EcE24377A_1034 Escherichia coli E24377A hypothetical protein YP_001462153.1 1059162 D 331111 CDS YP_001462154.1 157156986 5586484 complement(1059353..1060120) 1 NC_009801.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit 1060120 ssuB 5586484 ssuB Escherichia coli E24377A aliphatic sulfonates transport ATP-binding subunit YP_001462154.1 1059353 R 331111 CDS YP_001462155.1 157155333 5590695 complement(1060117..1060908) 1 NC_009801.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease subunit 1060908 ssuC 5590695 ssuC Escherichia coli E24377A alkanesulfonate transporter permease subunit YP_001462155.1 1060117 R 331111 CDS YP_001462156.1 157154796 5588937 complement(1060919..1062064) 1 NC_009801.1 catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 1062064 ssuD 5588937 ssuD Escherichia coli E24377A alkanesulfonate monooxygenase YP_001462156.1 1060919 R 331111 CDS YP_001462157.1 157158693 5588242 complement(1062302..1063027) 1 NC_009801.1 hypothetical protein 1063027 5588242 EcE24377A_1038 Escherichia coli E24377A hypothetical protein YP_001462157.1 1062302 R 331111 CDS YP_001462158.1 157155863 5588291 1063917..1064831 1 NC_009801.1 hypothetical protein 1064831 5588291 EcE24377A_1039 Escherichia coli E24377A hypothetical protein YP_001462158.1 1063917 D 331111 CDS YP_001462159.1 157157624 5588448 1064834..1065367 1 NC_009801.1 identified by match to protein family HMM PF02413; hypothetical protein 1065367 5588448 EcE24377A_1040 Escherichia coli E24377A hypothetical protein YP_001462159.1 1064834 D 331111 CDS YP_001462160.1 157156821 5586796 complement(1065396..1065923) 1 NC_009801.1 identified by match to protein family HMM PF02413; tail fiber assembly protein 1065923 gpG 5586796 gpG Escherichia coli E24377A tail fiber assembly protein YP_001462160.1 1065396 R 331111 CDS YP_001462161.1 157156132 5586406 complement(1065925..1067334) 1 NC_009801.1 identified by match to protein family HMM PF03406; phage tail fiber protein 1067334 5586406 EcE24377A_1042 Escherichia coli E24377A phage tail fiber protein YP_001462161.1 1065925 R 331111 CDS YP_001462162.1 157158351 5587785 complement(1067334..1067876) 1 NC_009801.1 hypothetical protein 1067876 5587785 EcE24377A_1043 Escherichia coli E24377A hypothetical protein YP_001462162.1 1067334 R 331111 CDS YP_001462163.1 157155596 5586977 complement(1067867..1068949) 1 NC_009801.1 identified by match to protein family HMM PF04865; baseplate assembly protein J 1068949 5586977 EcE24377A_1044 Escherichia coli E24377A baseplate assembly protein J YP_001462163.1 1067867 R 331111 CDS YP_001462164.1 157155258 5587165 complement(1068950..1069387) 1 NC_009801.1 identified by match to protein family HMM PF07409; phage protein GP46 1069387 5587165 EcE24377A_1045 Escherichia coli E24377A phage protein GP46 YP_001462164.1 1068950 R 331111 CDS YP_001462165.1 157155805 5590723 complement(1069384..1069977) 1 NC_009801.1 identified by match to protein family HMM PF06890; match to protein family HMM TIGR01644; phage baseplate assembly protein V 1069977 5590723 EcE24377A_1046 Escherichia coli E24377A phage baseplate assembly protein V YP_001462165.1 1069384 R 331111 CDS YP_001462166.1 157158597 5588683 complement(1069965..1071104) 1 NC_009801.1 identified by match to protein family HMM PF06893; bacteriophage Mu P protein 1071104 5588683 EcE24377A_1047 Escherichia coli E24377A bacteriophage Mu P protein YP_001462166.1 1069965 R 331111 CDS YP_001462167.1 157159157 5587806 complement(1071486..1073474) 1 NC_009801.1 identified by similarity to SP:P07636; match to protein family HMM PF02316; match to protein family HMM PF02914; match to protein family HMM PF09039; match to protein family HMM PF09299; bacteriophage Mu transposase MuA 1073474 5587806 EcE24377A_1049 Escherichia coli E24377A bacteriophage Mu transposase MuA YP_001462167.1 1071486 R 331111 CDS YP_001462168.1 157157154 5588543 1073889..1074413 1 NC_009801.1 identified by match to protein family HMM PF02316; repressor protein 1074413 5588543 EcE24377A_1050 Escherichia coli E24377A repressor protein YP_001462168.1 1073889 D 331111 CDS YP_001462169.1 157157790 5588796 complement(1074683..1075633) 1 NC_009801.1 identified by match to protein family HMM PF04069; match to protein family HMM TIGR01728; aliphatic sulfonate ABC transporter periplasmic substrate-binding protein 1075633 5588796 EcE24377A_1051 Escherichia coli E24377A aliphatic sulfonate ABC transporter periplasmic substrate-binding protein YP_001462169.1 1074683 R 331111 CDS YP_001462170.1 157156492 5589303 complement(1075584..1076159) 1 NC_009801.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358; NAD(P)H-dependent FMN reductase 1076159 5589303 EcE24377A_1052 Escherichia coli E24377A NAD(P)H-dependent FMN reductase YP_001462170.1 1075584 R 331111 CDS YP_001462171.1 157156929 5588923 1076515..1077057 1 NC_009801.1 identified by match to protein family HMM PF00419; fimbrial protein 1077057 5588923 EcE24377A_1053 Escherichia coli E24377A fimbrial protein YP_001462171.1 1076515 D 331111 CDS YP_001462172.1 157155029 5587586 1077140..1077841 1 NC_009801.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; periplasmic pilus chaperone family protein 1077841 5587586 EcE24377A_1054 Escherichia coli E24377A periplasmic pilus chaperone family protein YP_001462172.1 1077140 D 331111 CDS YP_001462173.1 157156978 5589171 1077866..1080466 1 NC_009801.1 identified by similarity to SP:P30130; match to protein family HMM PF00577; outer membrane usher protein fimD 1080466 fimD2 5589171 fimD2 Escherichia coli E24377A outer membrane usher protein fimD YP_001462173.1 1077866 D 331111 CDS YP_001462174.1 157156290 5590208 1080457..1081527 1 NC_009801.1 identified by match to protein family HMM PF00419; fimbrial protein 1081527 5590208 EcE24377A_1056 Escherichia coli E24377A fimbrial protein YP_001462174.1 1080457 D 331111 CDS YP_001462175.1 157157964 5588967 1081539..1082081 1 NC_009801.1 identified by match to protein family HMM PF00419; fimbrial protein 1082081 5588967 EcE24377A_1057 Escherichia coli E24377A fimbrial protein YP_001462175.1 1081539 D 331111 CDS YP_001462176.1 157159298 5589790 1082089..1082604 1 NC_009801.1 identified by match to protein family HMM PF00419; fimbrial protein 1082604 5589790 EcE24377A_1058 Escherichia coli E24377A fimbrial protein YP_001462176.1 1082089 D 331111 CDS YP_001462177.1 157157571 5589662 1082570..1083307 1 NC_009801.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; pili assembly chaperone 1083307 5589662 EcE24377A_1059 Escherichia coli E24377A pili assembly chaperone YP_001462177.1 1082570 D 331111 CDS YP_001462178.1 157158241 5586202 1083418..1084428 1 NC_009801.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1084428 pyrD 5586202 pyrD Escherichia coli E24377A dihydroorotate dehydrogenase 2 YP_001462178.1 1083418 D 331111 CDS YP_001462179.1 157156639 5586506 1084566..1085144 1 NC_009801.1 identified by match to protein family HMM PF07126; hypothetical protein 1085144 5586506 EcE24377A_1062 Escherichia coli E24377A hypothetical protein YP_001462179.1 1084566 D 331111 CDS YP_001462180.1 157154931 5587032 complement(1085141..1086250) 1 NC_009801.1 identified by match to protein family HMM PF00111; match to protein family HMM PF03473; match to protein family HMM PF03476; MOSC domain-containing protein 1086250 5587032 EcE24377A_1061 Escherichia coli E24377A MOSC domain-containing protein YP_001462180.1 1085141 R 331111 CDS YP_001462181.1 157155561 5587440 1086494..1088602 1 NC_009801.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1088602 rlmL 5587440 rlmL Escherichia coli E24377A 23S rRNA m(2)G2445 methyltransferase YP_001462181.1 1086494 D 331111 CDS YP_001462182.1 157158467 5589055 1088614..1090521 1 NC_009801.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1090521 uup 5589055 uup Escherichia coli E24377A ABC transporter ATPase YP_001462182.1 1088614 D 331111 CDS YP_001462183.1 157155514 5587548 1090651..1091904 1 NC_009801.1 identified by similarity to SP:P43670; match to protein family HMM PF04403; match to protein family HMM TIGR00155; paraquat-inducible protein A 1091904 pqiA 5587548 pqiA Escherichia coli E24377A paraquat-inducible protein A YP_001462183.1 1090651 D 331111 CDS YP_001462184.1 157155915 5587039 1091909..1093549 1 NC_009801.1 identified by similarity to SP:P43671; match to protein family HMM PF02470; paraquat-inducible protein B 1093549 pqiB 5587039 pqiB Escherichia coli E24377A paraquat-inducible protein B YP_001462184.1 1091909 D 331111 CDS YP_001462185.1 157156583 5588240 1093546..1094109 1 NC_009801.1 identified by match to protein family HMM PF03886; hypothetical protein 1094109 5588240 EcE24377A_1067 Escherichia coli E24377A hypothetical protein YP_001462185.1 1093546 D 331111 CDS YP_001462186.1 157157557 5587702 complement(1094602..1095120) 1 NC_009801.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 1095120 fabA 5587702 fabA Escherichia coli E24377A 3-hydroxydecanoyl-ACP dehydratase YP_001462186.1 1094602 R 331111 CDS YP_001462187.1 157158226 5588892 complement(1095189..1096949) 1 NC_009801.1 S16 family peptidase 1096949 5588892 EcE24377A_1069 Escherichia coli E24377A S16 family peptidase YP_001462187.1 1095189 R 331111 CDS YP_001462188.1 157158645 5588232 1097135..1097587 1 NC_009801.1 identified by match to protein family HMM PF06303; hypothetical protein 1097587 5588232 EcE24377A_1070 Escherichia coli E24377A hypothetical protein YP_001462188.1 1097135 D 331111 CDS YP_001462189.1 157159269 5589214 complement(1097662..1098714) 1 NC_009801.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A 1098714 ompA 5589214 ompA Escherichia coli E24377A outer membrane protein A YP_001462189.1 1097662 R 331111 CDS YP_001462190.1 157158822 5588382 1098869..1099087 1 NC_009801.1 identified by glimmer; hypothetical protein 1099087 5588382 EcE24377A_1073 Escherichia coli E24377A hypothetical protein YP_001462190.1 1098869 D 331111 CDS YP_001462191.1 157158913 5586838 complement(1099071..1099580) 1 NC_009801.1 identified by match to protein family HMM PF03846; match to protein family HMM TIGR00623; SOS cell division inhibitor 1099580 sulA 5586838 sulA Escherichia coli E24377A SOS cell division inhibitor YP_001462191.1 1099071 R 331111 CDS YP_001462192.1 157159114 5589090 1099799..1100428 1 NC_009801.1 identified by match to protein family HMM PF04993; match to protein family HMM PF04994; TfoX family protein 1100428 5589090 EcE24377A_1075 Escherichia coli E24377A TfoX family protein YP_001462192.1 1099799 D 331111 CDS YP_001462193.1 157157855 5587174 complement(1100391..1102553) 1 NC_009801.1 identified by match to protein family HMM PF05976; match to protein family HMM TIGR01666; match to protein family HMM TIGR01667; hypothetical protein 1102553 5587174 EcE24377A_1074 Escherichia coli E24377A hypothetical protein YP_001462193.1 1100391 R 331111 CDS YP_001462194.1 157155098 5589411 complement(1102563..1103009) 1 NC_009801.1 identified by match to protein family HMM PF03733; hypothetical protein 1103009 5589411 EcE24377A_1076 Escherichia coli E24377A hypothetical protein YP_001462194.1 1102563 R 331111 CDS YP_001462195.1 157155618 5588374 1103132..1105186 1 NC_009801.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1105186 helD 5588374 helD Escherichia coli E24377A DNA helicase IV YP_001462195.1 1103132 D 331111 CDS YP_001462196.1 157156482 5587017 complement(1105218..1105676) 1 NC_009801.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1105676 mgsA 5587017 mgsA Escherichia coli E24377A methylglyoxal synthase YP_001462196.1 1105218 R 331111 CDS YP_001462197.1 157156641 5589620 complement(1105772..1106434) 1 NC_009801.1 hypothetical protein 1106434 5589620 EcE24377A_1079 Escherichia coli E24377A hypothetical protein YP_001462197.1 1105772 R 331111 CDS YP_001462198.1 157156884 5587897 1106607..1107020 1 NC_009801.1 identified by match to protein family HMM PF02629; CoA-binding protein 1107020 5587897 EcE24377A_1080 Escherichia coli E24377A CoA-binding protein YP_001462198.1 1106607 D 331111 CDS YP_001462199.1 157156189 5586836 complement(1107065..1107382) 1 NC_009801.1 identified by similarity to SP:P0AB20; match to protein family HMM PF08755; match to protein family HMM TIGR02097; heat shock protein HspQ 1107382 5586836 EcE24377A_1081 Escherichia coli E24377A heat shock protein HspQ YP_001462199.1 1107065 R 331111 CDS YP_001462200.1 157155655 5588681 complement(1107440..1108630) 1 NC_009801.1 identified by match to protein family HMM PF03602; hypothetical protein 1108630 5588681 EcE24377A_1082 Escherichia coli E24377A hypothetical protein YP_001462200.1 1107440 R 331111 CDS YP_001462201.1 157155117 5588095 complement(1109000..1109329) 1 NC_009801.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE 1109329 tusE 5588095 tusE Escherichia coli E24377A sulfur transfer protein TusE YP_001462201.1 1109000 R 331111 CDS YP_001462202.1 157159032 5587240 complement(1109420..1110079) 1 NC_009801.1 identified by match to protein family HMM PF01027; hypothetical protein 1110079 5587240 EcE24377A_1084 Escherichia coli E24377A hypothetical protein YP_001462202.1 1109420 R 331111 CDS YP_001462203.1 157155331 5590626 1110800..1111918 1 NC_009801.1 identified by match to protein family HMM PF01058; match to protein family HMM PF08425; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409; nickel-dependent hydrogenase, small subunit 1111918 hyaA 5590626 hyaA Escherichia coli E24377A nickel-dependent hydrogenase, small subunit YP_001462203.1 1110800 D 331111 CDS YP_001462204.1 157158524 5588780 1111915..1113708 1 NC_009801.1 involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1113708 hyaB 5588780 hyaB Escherichia coli E24377A hydrogenase 1 large subunit YP_001462204.1 1111915 D 331111 CDS YP_001462205.1 157157370 5588155 1113727..1114434 1 NC_009801.1 identified by match to protein family HMM PF01292; match to protein family HMM TIGR02125; hydrogenase 1 b-type cytochrome subunit 1114434 hyaC 5588155 hyaC Escherichia coli E24377A hydrogenase 1 b-type cytochrome subunit YP_001462205.1 1113727 D 331111 CDS YP_001462206.1 157157868 5587860 1114431..1115018 1 NC_009801.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1115018 hyaD 5587860 hyaD Escherichia coli E24377A hydrogenase 1 maturation protease YP_001462206.1 1114431 D 331111 CDS YP_001462207.1 157156331 5586062 1115015..1115413 1 NC_009801.1 involved in processing hydrogenases HyaA and HyaB; hydrogenase-1 operon protein HyaE 1115413 hyaE 5586062 hyaE Escherichia coli E24377A hydrogenase-1 operon protein HyaE YP_001462207.1 1115015 D 331111 CDS YP_001462208.1 157156865 5590018 1115410..1116267 1 NC_009801.1 identified by similarity to SP:P19932; match to protein family HMM PF04809; hydrogenase-1 operon protein HyaF 1116267 hyaF 5590018 hyaF Escherichia coli E24377A hydrogenase-1 operon protein HyaF YP_001462208.1 1115410 D 331111 CDS YP_001462209.1 157155682 5588068 1116401..1117945 1 NC_009801.1 identified by match to protein family HMM PF01654; cytochrome bd-II oxidase subunit I 1117945 appC 5588068 appC Escherichia coli E24377A cytochrome bd-II oxidase subunit I YP_001462209.1 1116401 D 331111 CDS YP_001462210.1 157158801 5590706 1117957..1119093 1 NC_009801.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203; cytochrome bd-II oxidase subunit II 1119093 appB 5590706 appB Escherichia coli E24377A cytochrome bd-II oxidase subunit II YP_001462210.1 1117957 D 331111 CDS YP_001462211.1 157158417 5588673 1119106..1119198 1 NC_009801.1 expressed during stationary phase; membrane protein 1119198 5588673 EcE24377A_1095 Escherichia coli E24377A membrane protein YP_001462211.1 1119106 D 331111 CDS YP_001462212.1 157159123 5586193 1119278..1120576 1 NC_009801.1 identified by similarity to SP:P07102; match to protein family HMM PF00328; phosphoanhydride phosphorylase 1120576 appA 5586193 appA Escherichia coli E24377A phosphoanhydride phosphorylase YP_001462212.1 1119278 D 331111 CDS YP_001462213.1 157154890 5589119 complement(1120691..1122871) 1 NC_009801.1 identified by similarity to SP:P38134; match to protein family HMM PF02706; cryptic autophosphorylating protein tyrosine kinase Etk 1122871 etk 5589119 etk Escherichia coli E24377A cryptic autophosphorylating protein tyrosine kinase Etk YP_001462213.1 1120691 R 331111 CDS YP_001462214.1 157155359 5589756 complement(1122891..1123337) 1 NC_009801.1 Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk; phosphotyrosine-protein phosphatase 1123337 etp 5589756 etp Escherichia coli E24377A phosphotyrosine-protein phosphatase YP_001462214.1 1122891 R 331111 CDS YP_001462215.1 157156218 5589868 complement(1123325..1124485) 1 NC_009801.1 identified by match to protein family HMM PF02563; outer membrane lipoprotein, group 4 capsule (G4C) polysaccharide 1124485 yccZ 5589868 yccZ Escherichia coli E24377A outer membrane lipoprotein, group 4 capsule (G4C) polysaccharide YP_001462215.1 1123325 R 331111 CDS YP_001462216.1 157157653 5590266 complement(1124510..1126606) 1 NC_009801.1 identified by match to protein family HMM PF06082; lipoprotein 1126606 5590266 EcE24377A_1100 Escherichia coli E24377A lipoprotein YP_001462216.1 1124510 R 331111 CDS YP_001462217.1 157158170 5590053 complement(1126606..1127352) 1 NC_009801.1 identified by match to protein family HMM PF06251; hypothetical protein 1127352 5590053 EcE24377A_1101 Escherichia coli E24377A hypothetical protein YP_001462217.1 1126606 R 331111 CDS YP_001462218.1 157156862 5586477 complement(1127349..1127993) 1 NC_009801.1 group 4 capsule (G4C) polysaccharide, lipoprotein YmcC 1127993 ymcC 5586477 ymcC Escherichia coli E24377A group 4 capsule (G4C) polysaccharide, lipoprotein YmcC YP_001462218.1 1127349 R 331111 CDS YP_001462219.1 157156316 5589326 complement(1128100..1128423) 1 NC_009801.1 identified by similarity to SP:P75885; inner membrane protein 1128423 5589326 EcE24377A_1103 Escherichia coli E24377A inner membrane protein YP_001462219.1 1128100 R 331111 CDS YP_001462220.1 157158514 5586906 complement(1128847..1129059) 1 NC_009801.1 identified by match to protein family HMM PF00313; cold shock DNA-binding protein 1129059 5586906 EcE24377A_1104 Escherichia coli E24377A cold shock DNA-binding protein YP_001462220.1 1128847 R 331111 CDS YP_001462221.1 157157933 5588777 1129345..1129557 1 NC_009801.1 identified by match to protein family HMM PF00313; cold shock protein CspG 1129557 5588777 EcE24377A_1105 Escherichia coli E24377A cold shock protein CspG YP_001462221.1 1129345 D 331111 CDS YP_001462222.1 157157632 5589106 1129951..1130124 1 NC_009801.1 identified by match to protein family HMM PF08178; GnsA/GnsB family transcriptional regulator 1130124 5589106 EcE24377A_1107 Escherichia coli E24377A GnsA/GnsB family transcriptional regulator YP_001462222.1 1129951 D 331111 CDS YP_001462223.1 157158171 5588633 complement(1129966..1130139) 1 NC_009801.1 identified by glimmer; hypothetical protein 1130139 5588633 EcE24377A_1106 Escherichia coli E24377A hypothetical protein YP_001462223.1 1129966 R 331111 CDS YP_001462224.1 157156552 5588867 complement(1130172..1131245) 1 NC_009801.1 yccM; identified by match to protein family HMM PF00037; 4Fe-4S ferredoxin 1131245 5588867 EcE24377A_1108 Escherichia coli E24377A 4Fe-4S ferredoxin YP_001462224.1 1130172 R 331111 CDS YP_001462225.1 157156051 5586409 complement(1131119..1131283) 1 NC_009801.1 identified by glimmer; hypothetical protein 1131283 5586409 EcE24377A_1109 Escherichia coli E24377A hypothetical protein YP_001462225.1 1131119 R 331111 CDS YP_001462226.1 157158585 5588660 complement(1131317..1134061) 1 NC_009801.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS 1134061 torS 5588660 torS Escherichia coli E24377A hybrid sensory histidine kinase TorS YP_001462226.1 1131317 R 331111 CDS YP_001462227.1 157155126 5586053 1134144..1135172 1 NC_009801.1 periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1135172 torT 5586053 torT Escherichia coli E24377A TMAO reductase system periplasmic protein TorT YP_001462227.1 1134144 D 331111 CDS YP_001462228.1 157158972 5586934 complement(1135145..1135837) 1 NC_009801.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR 1135837 torR 5586934 torR Escherichia coli E24377A DNA-binding transcriptional regulator TorR YP_001462228.1 1135145 R 331111 CDS YP_001462229.1 157155491 5586657 1135967..1137139 1 NC_009801.1 identified by similarity to SP:P33226; match to protein family HMM PF03264; match to protein family HMM TIGR02162; cytochrome c-type protein torC 1137139 torC 5586657 torC Escherichia coli E24377A cytochrome c-type protein torC YP_001462229.1 1135967 D 331111 CDS YP_001462230.1 157155850 5588001 1137139..1139685 1 NC_009801.1 identified by similarity to SP:P33225; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409; match to protein family HMM TIGR02164; trimethylamine-N-oxide reductase 1139685 torA 5588001 torA Escherichia coli E24377A trimethylamine-N-oxide reductase YP_001462230.1 1137139 D 331111 CDS YP_001462231.1 157156231 5587048 1139682..1140281 1 NC_009801.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1140281 torD 5587048 torD Escherichia coli E24377A chaperone protein TorD YP_001462231.1 1139682 D 331111 CDS YP_001462232.1 157156655 5590303 complement(1140221..1140370) 1 NC_009801.1 identified by glimmer; hypothetical protein 1140370 5590303 EcE24377A_1115 Escherichia coli E24377A hypothetical protein YP_001462232.1 1140221 R 331111 CDS YP_001462233.1 157158092 5589569 complement(1140374..1140679) 1 NC_009801.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM 1140679 cbpM 5589569 cbpM Escherichia coli E24377A chaperone-modulator protein CbpM YP_001462233.1 1140374 R 331111 CDS YP_001462234.1 157157841 5586164 complement(1140679..1141599) 1 NC_009801.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA 1141599 cbpA 5586164 cbpA Escherichia coli E24377A curved DNA-binding protein CbpA YP_001462234.1 1140679 R 331111 CDS YP_001462235.1 157157400 5589296 1141859..1143118 1 NC_009801.1 identified by similarity to GB:AAP16515.1; hypothetical protein 1143118 5589296 EcE24377A_1119 Escherichia coli E24377A hypothetical protein YP_001462235.1 1141859 D 331111 CDS YP_001462236.1 157158962 5589155 1143409..1144650 1 NC_009801.1 identified by similarity to SP:P19926; match to protein family HMM PF00328; glucose-1-phosphatase/inositol phosphatase 1144650 agp 5589155 agp Escherichia coli E24377A glucose-1-phosphatase/inositol phosphatase YP_001462236.1 1143409 D 331111 CDS YP_001462237.1 157158367 5589815 complement(1144688..1144915) 1 NC_009801.1 hypothetical protein 1144915 5589815 EcE24377A_1121 Escherichia coli E24377A hypothetical protein YP_001462237.1 1144688 R 331111 CDS YP_001462238.1 157158115 5588061 complement(1144936..1145532) 1 NC_009801.1 stationary phase that binds TrpR repressor; TrpR binding protein WrbA 1145532 wrbA 5588061 wrbA Escherichia coli E24377A TrpR binding protein WrbA YP_001462238.1 1144936 R 331111 CDS YP_001462239.1 157157480 5587088 1145905..1146078 1 NC_009801.1 identified by similarity to GB:BAA35782.1; hypothetical protein 1146078 5587088 EcE24377A_1123 Escherichia coli E24377A hypothetical protein YP_001462239.1 1145905 D 331111 CDS YP_001462240.1 157159382 5587228 complement(1146161..1147489) 1 NC_009801.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; purine permease ycdG 1147489 5587228 EcE24377A_1124 Escherichia coli E24377A purine permease ycdG YP_001462240.1 1146161 R 331111 CDS YP_001462241.1 157158870 5588270 complement(1147510..1148004) 1 NC_009801.1 identified by similarity to SP:P75893; match to protein family HMM PF01613; flavin reductase rutF 1148004 5588270 EcE24377A_1125 Escherichia coli E24377A flavin reductase rutF YP_001462241.1 1147510 R 331111 CDS YP_001462242.1 157156722 5587315 complement(1148015..1148605) 1 NC_009801.1 identified by similarity to SP:P75894; match to protein family HMM PF00881; hypothetical protein 1148605 5587315 EcE24377A_1126 Escherichia coli E24377A hypothetical protein YP_001462242.1 1148015 R 331111 CDS YP_001462243.1 157154886 5586931 complement(1148615..1149415) 1 NC_009801.1 identified by similarity to SP:P75895; match to protein family HMM PF00561; rutD protein 1149415 5586931 EcE24377A_1127 Escherichia coli E24377A rutD protein YP_001462243.1 1148615 R 331111 CDS YP_001462244.1 157155569 5587950 complement(1149423..1149809) 1 NC_009801.1 identified by similarity to SP:P0AFQ5; match to protein family HMM PF01042; rutC protein 1149809 5587950 EcE24377A_1128 Escherichia coli E24377A rutC protein YP_001462244.1 1149423 R 331111 CDS YP_001462245.1 157158711 5589697 complement(1149821..1150516) 1 NC_009801.1 identified by similarity to SP:P75897; match to protein family HMM PF00857; isochorismatase, rutB 1150516 5589697 EcE24377A_1129 Escherichia coli E24377A isochorismatase, rutB YP_001462245.1 1149821 R 331111 CDS YP_001462246.1 157155454 5589956 complement(1150513..1151694) 1 NC_009801.1 identified by similarity to SP:P75898; match to protein family HMM PF00296; monooxygenase rutA 1151694 5589956 EcE24377A_1130 Escherichia coli E24377A monooxygenase rutA YP_001462246.1 1150513 R 331111 CDS YP_001462247.1 157158459 5588865 1151891..1152529 1 NC_009801.1 identified by similarity to SP:P0ACU2; match to protein family HMM PF00440; match to protein family HMM PF08362; transcriptional regulator RutR 1152529 rutR 5588865 rutR Escherichia coli E24377A transcriptional regulator RutR YP_001462247.1 1151891 D 331111 CDS YP_001462248.1 157158674 5585999 complement(1152569..1156531) 1 NC_009801.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1156531 putA 5585999 putA Escherichia coli E24377A trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_001462248.1 1152569 R 331111 CDS YP_001462249.1 157157996 5586666 1156586..1156795 1 NC_009801.1 hypothetical protein 1156795 5586666 EcE24377A_1134 Escherichia coli E24377A hypothetical protein YP_001462249.1 1156586 D 331111 CDS YP_001462250.1 157156407 5589726 1156954..1158462 1 NC_009801.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121; sodium/proline symporter 1158462 putP 5589726 putP Escherichia coli E24377A sodium/proline symporter YP_001462250.1 1156954 D 331111 CDS YP_001462251.1 157156355 5586702 1159004..1159834 1 NC_009801.1 identified by match to protein family HMM PF03239; match to protein family HMM TIGR00145; FTR1 family iron permease 1159834 5586702 EcE24377A_1136 Escherichia coli E24377A FTR1 family iron permease YP_001462251.1 1159004 D 331111 CDS YP_001462252.1 157156898 5588498 1159892..1161019 1 NC_009801.1 identified by match to protein family HMM PF04302; hypothetical protein 1161019 5588498 EcE24377A_1137 Escherichia coli E24377A hypothetical protein YP_001462252.1 1159892 D 331111 CDS YP_001462253.1 157157331 5589030 1161025..1162296 1 NC_009801.1 identified by match to protein family HMM PF04261; match to protein family HMM TIGR01409; match to protein family HMM TIGR01412; match to protein family HMM TIGR01413; Tat-translocated enzyme 1162296 5589030 EcE24377A_1138 Escherichia coli E24377A Tat-translocated enzyme YP_001462253.1 1161025 D 331111 CDS YP_001462254.1 157157900 5588737 complement(1162363..1162560) 1 NC_009801.1 identified by glimmer; hypothetical protein 1162560 5588737 EcE24377A_1139 Escherichia coli E24377A hypothetical protein YP_001462254.1 1162363 R 331111 CDS YP_001462255.1 157158963 5588317 complement(1163753..1164166) 1 NC_009801.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; PGA biosynthesis protein 1164166 pgaD 5588317 pgaD Escherichia coli E24377A PGA biosynthesis protein YP_001462255.1 1163753 R 331111 CDS YP_001462256.1 157157335 5589816 complement(1164168..1165493) 1 NC_009801.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 1165493 pgaC 5589816 pgaC Escherichia coli E24377A N-glycosyltransferase YP_001462256.1 1164168 R 331111 CDS YP_001462257.1 157157853 5587951 complement(1165486..1167504) 1 NC_009801.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase 1167504 pgaB 5587951 pgaB Escherichia coli E24377A outer membrane N-deacetylase YP_001462257.1 1165486 R 331111 CDS YP_001462258.1 157158435 5588807 complement(1167513..1169936) 1 NC_009801.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA 1169936 pgaA 5588807 pgaA Escherichia coli E24377A outer membrane protein PgaA YP_001462258.1 1167513 R 331111 CDS YP_001462259.1 157158903 5588047 1170451..1171881 1 NC_009801.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 1171881 5588047 EcE24377A_1145 Escherichia coli E24377A diguanylate cyclase YP_001462259.1 1170451 D 331111 CDS YP_001462260.1 157159400 5589503 complement(1171922..1172788) 1 NC_009801.1 identified by similarity to SP:P05822; match to protein family HMM PF00665; IS3, transposase orfB 1172788 5589503 EcE24377A_1146 Escherichia coli E24377A IS3, transposase orfB YP_001462260.1 1171922 R 331111 CDS YP_001462261.1 157155285 5590062 complement(1172785..1173084) 1 NC_009801.1 identified by match to protein family HMM PF01527; IS3, transposase orfA 1173084 5590062 EcE24377A_1147 Escherichia coli E24377A IS3, transposase orfA YP_001462261.1 1172785 R 331111 CDS YP_001462262.1 157155666 5585947 1173134..1173499 1 NC_009801.1 identified by glimmer; hypothetical protein 1173499 5585947 EcE24377A_1148 Escherichia coli E24377A hypothetical protein YP_001462262.1 1173134 D 331111 CDS YP_001462263.1 157156350 5590322 1173489..1174475 1 NC_009801.1 hypothetical protein 1174475 5590322 EcE24377A_1149 Escherichia coli E24377A hypothetical protein YP_001462263.1 1173489 D 331111 CDS YP_001462264.1 157157820 5590802 complement(1175217..1175330) 1 NC_009801.1 identified by glimmer; hypothetical protein 1175330 5590802 EcE24377A_1151 Escherichia coli E24377A hypothetical protein YP_001462264.1 1175217 R 331111 CDS YP_001462265.1 157154960 5588410 1176344..1177081 1 NC_009801.1 identified by match to protein family HMM PF02811; hydrolase 1177081 5588410 EcE24377A_1153 Escherichia coli E24377A hydrolase YP_001462265.1 1176344 D 331111 CDS YP_001462266.1 157155138 5588932 1177105..1177659 1 NC_009801.1 identified by match to protein family HMM PF06192; chaperone TorD 1177659 5588932 EcE24377A_1154 Escherichia coli E24377A chaperone TorD YP_001462266.1 1177105 D 331111 CDS YP_001462267.1 157155603 5589678 1177761..1178252 1 NC_009801.1 identified by match to protein family HMM PF06496; hypothetical protein 1178252 5589678 EcE24377A_1155 Escherichia coli E24377A hypothetical protein YP_001462267.1 1177761 D 331111 CDS YP_001462268.1 157157085 5589575 complement(1178316..1179149) 1 NC_009801.1 identified by match to protein family HMM PF03783; curli production assembly/transport subunit CsgG 1179149 csgG 5589575 csgG Escherichia coli E24377A curli production assembly/transport subunit CsgG YP_001462268.1 1178316 R 331111 CDS YP_001462269.1 157156394 5587494 complement(1179176..1179592) 1 NC_009801.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF 1179592 csgF 5587494 csgF Escherichia coli E24377A curli assembly protein CsgF YP_001462269.1 1179176 R 331111 CDS YP_001462270.1 157156361 5590765 complement(1179617..1180006) 1 NC_009801.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE 1180006 csgE 5590765 csgE Escherichia coli E24377A curli assembly protein CsgE YP_001462270.1 1179617 R 331111 CDS YP_001462271.1 157155649 5590727 complement(1180011..1180661) 1 NC_009801.1 activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD 1180661 csgD 5590727 csgD Escherichia coli E24377A DNA-binding transcriptional regulator CsgD YP_001462271.1 1180011 R 331111 CDS YP_001462272.1 157155137 5588920 complement(1181073..1181321) 1 NC_009801.1 identified by glimmer; hypothetical protein 1181321 5588920 EcE24377A_1160 Escherichia coli E24377A hypothetical protein YP_001462272.1 1181073 R 331111 CDS YP_001462273.1 157158515 5589677 1181388..1181870 1 NC_009801.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1181870 csgB 5589677 csgB Escherichia coli E24377A curlin minor subunit YP_001462273.1 1181388 D 331111 CDS YP_001462274.1 157157267 5588778 1181911..1182366 1 NC_009801.1 identified by similarity to SP:P28307; match to protein family HMM PF07012; cryptic curlin major subunit 1182366 5588778 EcE24377A_1162 Escherichia coli E24377A cryptic curlin major subunit YP_001462274.1 1181911 D 331111 CDS YP_001462275.1 157156575 5587878 1182425..1182757 1 NC_009801.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1182757 csgC 5587878 csgC Escherichia coli E24377A autoagglutination protein YP_001462275.1 1182425 D 331111 CDS YP_001462276.1 157156416 5587511 1182878..1183189 1 NC_009801.1 hypothetical protein 1183189 5587511 EcE24377A_1164 Escherichia coli E24377A hypothetical protein YP_001462276.1 1182878 D 331111 CDS YP_001462277.1 157155706 5589746 1183284..1183817 1 NC_009801.1 identified by match to protein family HMM PF01661; hypothetical protein 1183817 5589746 EcE24377A_1165 Escherichia coli E24377A hypothetical protein YP_001462277.1 1183284 D 331111 CDS YP_001462278.1 157156460 5589506 1183810..1185240 1 NC_009801.1 identified by match to protein family HMM PF00614; phopholipase D 1185240 5589506 EcE24377A_1166 Escherichia coli E24377A phopholipase D YP_001462278.1 1183810 D 331111 CDS YP_001462279.1 157156321 5586057 complement(1185248..1186405) 1 NC_009801.1 required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein 1186405 mdoC 5586057 mdoC Escherichia coli E24377A glucans biosynthesis protein YP_001462279.1 1185248 R 331111 CDS YP_001462280.1 157155624 5589081 complement(1186450..1186593) 1 NC_009801.1 identified by glimmer; hypothetical protein 1186593 5589081 EcE24377A_1168 Escherichia coli E24377A hypothetical protein YP_001462280.1 1186450 R 331111 CDS YP_001462281.1 157156764 5590258 1186799..1188334 1 NC_009801.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1188334 mdoG 5590258 mdoG Escherichia coli E24377A glucan biosynthesis protein G YP_001462281.1 1186799 D 331111 CDS YP_001462282.1 157159340 5589701 1188327..1190870 1 NC_009801.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1190870 mdoH 5589701 mdoH Escherichia coli E24377A glucosyltransferase MdoH YP_001462282.1 1188327 D 331111 CDS YP_001462283.1 157157394 5587296 1191043..1191270 1 NC_009801.1 identified by match to protein family HMM PF07119; hypothetical protein 1191270 5587296 EcE24377A_1172 Escherichia coli E24377A hypothetical protein YP_001462283.1 1191043 D 331111 CDS YP_001462284.1 157157935 5589418 complement(1191271..1191645) 1 NC_009801.1 hypothetical protein 1191645 msyB 5589418 msyB Escherichia coli E24377A hypothetical protein YP_001462284.1 1191271 R 331111 CDS YP_001462285.1 157156375 5588013 complement(1191728..1192954) 1 NC_009801.1 Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG 1192954 mdtG 5588013 mdtG Escherichia coli E24377A drug efflux system protein MdtG YP_001462285.1 1191728 R 331111 CDS YP_001462286.1 157156890 5589427 1192984..1193088 1 NC_009801.1 identified by glimmer; hypothetical protein 1193088 5589427 EcE24377A_1175 Escherichia coli E24377A hypothetical protein YP_001462286.1 1192984 D 331111 CDS YP_001462287.1 157155736 5589925 complement(1193126..1194046) 1 NC_009801.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1194046 htrB 5589925 htrB Escherichia coli E24377A lipid A biosynthesis lauroyl acyltransferase YP_001462287.1 1193126 R 331111 CDS YP_001462288.1 157158651 5590866 1194271..1195323 1 NC_009801.1 identified by match to protein family HMM PF00581; hypothetical protein 1195323 5590866 EcE24377A_1177 Escherichia coli E24377A hypothetical protein YP_001462288.1 1194271 D 331111 CDS YP_001462289.1 157159017 5589370 complement(1195365..1195940) 1 NC_009801.1 identified by match to protein family HMM PF04264; hypothetical protein 1195940 yceI 5589370 yceI Escherichia coli E24377A hypothetical protein YP_001462289.1 1195365 R 331111 CDS YP_001462290.1 157157617 5587837 complement(1195944..1196510) 1 NC_009801.1 identified by match to protein family HMM PF01292; nickel-dependent hydrogenase b-type cytochrome subunit 1196510 5587837 EcE24377A_1179 Escherichia coli E24377A nickel-dependent hydrogenase b-type cytochrome subunit YP_001462290.1 1195944 R 331111 CDS YP_001462291.1 157157977 5590128 1196500..1196646 1 NC_009801.1 hypothetical protein 1196646 5590128 EcE24377A_1180 Escherichia coli E24377A hypothetical protein YP_001462291.1 1196500 D 331111 CDS YP_001462292.1 157155996 5590457 complement(1196771..1196884) 1 NC_009801.1 identified by similarity to RF:NP_460130.1; hypothetical protein 1196884 5590457 EcE24377A_1181 Escherichia coli E24377A hypothetical protein YP_001462292.1 1196771 R 331111 CDS YP_001462293.1 157155462 5588901 complement(1196932..1198050) 1 NC_009801.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 1198050 solA 5588901 solA Escherichia coli E24377A N-methyltryptophan oxidase YP_001462293.1 1196932 R 331111 CDS YP_001462294.1 157158397 5587441 complement(1198165..1198422) 1 NC_009801.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS 1198422 bssS 5587441 bssS Escherichia coli E24377A biofilm formation regulatory protein BssS YP_001462294.1 1198165 R 331111 CDS YP_001462295.1 157158610 5590237 complement(1198709..1198954) 1 NC_009801.1 identified by similarity to SP:P0ABR4; match to protein family HMM PF06183; DNA damage-inducible protein I 1198954 dinI 5590237 dinI Escherichia coli E24377A DNA damage-inducible protein I YP_001462295.1 1198709 R 331111 CDS YP_001462296.1 157157354 5586994 complement(1199028..1200074) 1 NC_009801.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1200074 pyrC 5586994 pyrC Escherichia coli E24377A dihydroorotase YP_001462296.1 1199028 R 331111 CDS YP_001462297.1 157154992 5588299 complement(1200180..1200740) 1 NC_009801.1 identified by match to protein family HMM PF07273; hypothetical protein 1200740 5588299 EcE24377A_1186 Escherichia coli E24377A hypothetical protein YP_001462297.1 1200180 R 331111 CDS YP_001462298.1 157155546 5589478 complement(1200874..1201521) 1 NC_009801.1 cofactor involved in the reduction of disulfides; glutaredoxin 1201521 grxB 5589478 grxB Escherichia coli E24377A glutaredoxin YP_001462298.1 1200874 R 331111 CDS YP_001462299.1 157155944 5586168 complement(1201585..1202793) 1 NC_009801.1 Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 1202793 mdtH 5586168 mdtH Escherichia coli E24377A multidrug resistance protein MdtH YP_001462299.1 1201585 R 331111 CDS YP_001462300.1 157156754 5587278 1203029..1203613 1 NC_009801.1 identified by similarity to SP:P0A948; match to protein family HMM PF00583; ribosomal-protein-S5-alanine N-acetyltransferase 1203613 rimJ 5587278 rimJ Escherichia coli E24377A ribosomal-protein-S5-alanine N-acetyltransferase YP_001462300.1 1203029 D 331111 CDS YP_001462301.1 157155438 5586121 1203624..1204271 1 NC_009801.1 identified by match to protein family HMM PF04337; hypothetical protein 1204271 5586121 EcE24377A_1190 Escherichia coli E24377A hypothetical protein YP_001462301.1 1203624 D 331111 CDS YP_001462302.1 157158513 5588630 1204273..1205196 1 NC_009801.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase 1205196 5588630 EcE24377A_1191 Escherichia coli E24377A oxidoreductase YP_001462302.1 1204273 D 331111 CDS YP_001462303.1 157157105 5589498 1205306..1206841 1 NC_009801.1 identified by match to protein family HMM PF03023; match to protein family HMM TIGR01695; integral membrane protein MviN 1206841 mviN 5589498 mviN Escherichia coli E24377A integral membrane protein MviN YP_001462303.1 1205306 D 331111 CDS YP_001462304.1 157154753 5590355 complement(1206881..1207297) 1 NC_009801.1 identified by match to protein family HMM PF05130; flagellar synthesis protein FlgN 1207297 flgN 5590355 flgN Escherichia coli E24377A flagellar synthesis protein FlgN YP_001462304.1 1206881 R 331111 CDS YP_001462305.1 157157558 5590469 complement(1207302..1207595) 1 NC_009801.1 regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM 1207595 flgM 5590469 flgM Escherichia coli E24377A anti-sigma-28 factor FlgM YP_001462305.1 1207302 R 331111 CDS YP_001462306.1 157158222 5588893 complement(1207671..1208330) 1 NC_009801.1 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 1208330 flgA 5588893 flgA Escherichia coli E24377A flagellar basal body P-ring biosynthesis protein FlgA YP_001462306.1 1207671 R 331111 CDS YP_001462307.1 157157889 5590087 1208485..1208901 1 NC_009801.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal-body rod protein FlgB 1208901 flgB 5590087 flgB Escherichia coli E24377A flagellar basal-body rod protein FlgB YP_001462307.1 1208485 D 331111 CDS YP_001462308.1 157158527 5588717 1208905..1209309 1 NC_009801.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1209309 flgC 5588717 flgC Escherichia coli E24377A flagellar basal body rod protein FlgC YP_001462308.1 1208905 D 331111 CDS YP_001462309.1 157157345 5587507 1209321..1210016 1 NC_009801.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1210016 flgD 5587507 flgD Escherichia coli E24377A flagellar basal body rod modification protein YP_001462309.1 1209321 D 331111 CDS YP_001462310.1 157157539 5590183 1210041..1211246 1 NC_009801.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1211246 flgE 5590183 flgE Escherichia coli E24377A flagellar hook protein FlgE YP_001462310.1 1210041 D 331111 CDS YP_001462311.1 157155680 5589625 1211266..1212021 1 NC_009801.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1212021 flgF 5589625 flgF Escherichia coli E24377A flagellar basal body rod protein FlgF YP_001462311.1 1211266 D 331111 CDS YP_001462312.1 157156521 5589807 1212159..1212941 1 NC_009801.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1212941 flgG 5589807 flgG Escherichia coli E24377A flagellar basal body rod protein FlgG YP_001462312.1 1212159 D 331111 CDS YP_001462313.1 157155075 5587566 1212994..1213692 1 NC_009801.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1213692 flgH 5587566 flgH Escherichia coli E24377A flagellar basal body L-ring protein YP_001462313.1 1212994 D 331111 CDS YP_001462314.1 157155720 5588018 1213704..1214801 1 NC_009801.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 1214801 flgI 5588018 flgI Escherichia coli E24377A flagellar basal body P-ring biosynthesis protein FlgA YP_001462314.1 1213704 D 331111 CDS YP_001462315.1 157158487 5586381 1214801..1215742 1 NC_009801.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1215742 flgJ 5586381 flgJ Escherichia coli E24377A flagellar rod assembly protein/muramidase FlgJ YP_001462315.1 1214801 D 331111 CDS YP_001462316.1 157159090 5590294 1215808..1217451 1 NC_009801.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1217451 flgK 5590294 flgK Escherichia coli E24377A flagellar hook-associated protein FlgK YP_001462316.1 1215808 D 331111 CDS YP_001462317.1 157155540 5590180 1217463..1218416 1 NC_009801.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1218416 flgL 5590180 flgL Escherichia coli E24377A flagellar hook-associated protein FlgL YP_001462317.1 1217463 D 331111 CDS YP_001462318.1 157159193 5587728 complement(1218613..1221798) 1 NC_009801.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 1221798 rne 5587728 rne Escherichia coli E24377A ribonuclease E YP_001462318.1 1218613 R 331111 CDS YP_001462319.1 157156049 5589539 1222371..1223330 1 NC_009801.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1223330 rluC 5589539 rluC Escherichia coli E24377A 23S rRNA pseudouridylate synthase C YP_001462319.1 1222371 D 331111 CDS YP_001462320.1 157155486 5588658 complement(1223442..1224065) 1 NC_009801.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1224065 maf2 5588658 maf2 Escherichia coli E24377A Maf-like protein YP_001462320.1 1223442 R 331111 CDS YP_001462321.1 157157658 5588489 1224225..1224746 1 NC_009801.1 identified by match to protein family HMM PF02620; hypothetical protein 1224746 5588489 EcE24377A_1210 Escherichia coli E24377A hypothetical protein YP_001462321.1 1224225 D 331111 CDS YP_001462322.1 157156578 5590026 1225052..1226122 1 NC_009801.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1226122 plsX 5590026 plsX Escherichia coli E24377A glycerol-3-phosphate acyltransferase PlsX YP_001462322.1 1225052 D 331111 CDS YP_001462323.1 157157671 5586313 1226190..1227143 1 NC_009801.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1227143 fabH 5586313 fabH Escherichia coli E24377A 3-oxoacyl-ACP synthase YP_001462323.1 1226190 D 331111 CDS YP_001462324.1 157154947 5589212 1227159..1228088 1 NC_009801.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128; malonyl CoA-acyl carrier protein transacylase 1228088 fabD 5589212 fabD Escherichia coli E24377A malonyl CoA-acyl carrier protein transacylase YP_001462324.1 1227159 D 331111 CDS YP_001462325.1 157158722 5590805 1228101..1228835 1 NC_009801.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1228835 fabG 5590805 fabG Escherichia coli E24377A 3-ketoacyl-ACP reductase YP_001462325.1 1228101 D 331111 CDS YP_001462326.1 157155602 5588521 1229046..1229282 1 NC_009801.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1229282 acpP 5588521 acpP Escherichia coli E24377A acyl carrier protein YP_001462326.1 1229046 D 331111 CDS YP_001462327.1 157159057 5587541 1229370..1230611 1 NC_009801.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1230611 fabF 5587541 fabF Escherichia coli E24377A 3-oxoacyl-ACP synthase YP_001462327.1 1229370 D 331111 CDS YP_001462328.1 157158567 5590011 1230731..1231540 1 NC_009801.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1231540 pabC 5590011 pabC Escherichia coli E24377A 4-amino-4-deoxychorismate lyase YP_001462328.1 1230731 D 331111 CDS YP_001462329.1 157156476 5590738 1231543..1232565 1 NC_009801.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247; hypothetical protein 1232565 5590738 EcE24377A_1218 Escherichia coli E24377A hypothetical protein YP_001462329.1 1231543 D 331111 CDS YP_001462330.1 157157223 5589938 1232555..1233196 1 NC_009801.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1233196 tmk 5589938 tmk Escherichia coli E24377A thymidylate kinase YP_001462330.1 1232555 D 331111 CDS YP_001462331.1 157157017 5586615 1233193..1234197 1 NC_009801.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1234197 holB 5586615 holB Escherichia coli E24377A DNA polymerase III subunit delta' YP_001462331.1 1233193 D 331111 CDS YP_001462332.1 157156294 5589878 1234208..1235005 1 NC_009801.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; metallodependent hydrolase 1235005 5589878 EcE24377A_1221 Escherichia coli E24377A metallodependent hydrolase YP_001462332.1 1234208 D 331111 CDS YP_001462333.1 157158322 5589194 1235300..1236733 1 NC_009801.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC 1236733 ptsG 5589194 ptsG Escherichia coli E24377A PTS system glucose-specific transporter subunit IIBC YP_001462333.1 1235300 D 331111 CDS YP_001462334.1 157155265 5588326 complement(1236793..1238982) 1 NC_009801.1 identified by similarity to SP:P16869; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783; ferric-rhodotorulic acid outer membrane transporter 1238982 fhuE 5588326 fhuE Escherichia coli E24377A ferric-rhodotorulic acid outer membrane transporter YP_001462334.1 1236793 R 331111 CDS YP_001462335.1 157155124 5590528 complement(1239015..1239185) 1 NC_009801.1 hypothetical protein 1239185 5590528 EcE24377A_1224 Escherichia coli E24377A hypothetical protein YP_001462335.1 1239015 R 331111 CDS YP_001462336.1 157155668 5587061 1239316..1239675 1 NC_009801.1 identified by similarity to SP:P0ACE7; match to protein family HMM PF01230; purine nucleoside phosphoramidase 1239675 hinT 5587061 hinT Escherichia coli E24377A purine nucleoside phosphoramidase YP_001462336.1 1239316 D 331111 CDS YP_001462337.1 157155136 5590324 1239678..1240055 1 NC_009801.1 identified by match to protein family HMM PF07233; lipoprotein 1240055 5590324 EcE24377A_1226 Escherichia coli E24377A lipoprotein YP_001462337.1 1239678 D 331111 CDS YP_001462338.1 157157010 5589067 1240069..1240710 1 NC_009801.1 identified by match to protein family HMM TIGR02722; lipoprotein 1240710 5589067 EcE24377A_1227 Escherichia coli E24377A lipoprotein YP_001462338.1 1240069 D 331111 CDS YP_001462339.1 157156457 5589021 1240691..1241515 1 NC_009801.1 catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1241515 thiK 5589021 thiK Escherichia coli E24377A thiamine kinase YP_001462339.1 1240691 D 331111 CDS YP_001462340.1 157157822 5590708 1241526..1242551 1 NC_009801.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1242551 nagZ 5590708 nagZ Escherichia coli E24377A beta-hexosaminidase YP_001462340.1 1241526 D 331111 CDS YP_001462341.1 157157196 5590185 1242574..1243116 1 NC_009801.1 identified by match to protein family HMM PF05728; hypothetical protein 1243116 5590185 EcE24377A_1230 Escherichia coli E24377A hypothetical protein YP_001462341.1 1242574 D 331111 CDS YP_001462342.1 157159026 5590426 1243524..1244828 1 NC_009801.1 identified by similarity to SP:P00393; match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF07992; NADH dehydrogenase 1244828 ndh 5590426 ndh Escherichia coli E24377A NADH dehydrogenase YP_001462342.1 1243524 D 331111 CDS YP_001462343.1 157158480 5588547 1245055..1245594 1 NC_009801.1 identified by match to protein family HMM PF05433; hypothetical protein 1245594 5588547 EcE24377A_1232 Escherichia coli E24377A hypothetical protein YP_001462343.1 1245055 D 331111 CDS YP_001462344.1 157157182 5590402 complement(1245656..1246366) 1 NC_009801.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1246366 5590402 EcE24377A_1233 Escherichia coli E24377A TetR family transcriptional regulator YP_001462344.1 1245656 R 331111 CDS YP_001462345.1 157157687 5586681 1246529..1246786 1 NC_009801.1 identified by match to protein family HMM PF07338; hypothetical protein 1246786 5586681 EcE24377A_1234 Escherichia coli E24377A hypothetical protein YP_001462345.1 1246529 D 331111 CDS YP_001462346.1 157159394 5590513 complement(1246869..1247831) 1 NC_009801.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734; LysM/ErfK/YbiS/YcfS/YnhG family protein 1247831 5590513 EcE24377A_1235 Escherichia coli E24377A LysM/ErfK/YbiS/YcfS/YnhG family protein YP_001462346.1 1246869 R 331111 CDS YP_001462347.1 157158427 5590455 complement(1247975..1251421) 1 NC_009801.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580; transcription-repair coupling factor 1251421 mfd 5590455 mfd Escherichia coli E24377A transcription-repair coupling factor YP_001462347.1 1247975 R 331111 CDS YP_001462348.1 157155372 5589207 complement(1251549..1252622) 1 NC_009801.1 identified by match to protein family HMM PF01757; hypothetical protein 1252622 5589207 EcE24377A_1237 Escherichia coli E24377A hypothetical protein YP_001462348.1 1251549 R 331111 CDS YP_001462349.1 157154974 5590529 1252884..1254083 1 NC_009801.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1254083 lolC 5590529 lolC Escherichia coli E24377A outer membrane-specific lipoprotein transporter subunit LolC YP_001462349.1 1252884 D 331111 CDS YP_001462350.1 157156466 5587325 1254076..1254777 1 NC_009801.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1254777 lolD 5587325 lolD Escherichia coli E24377A lipoprotein transporter ATP-binding subunit YP_001462350.1 1254076 D 331111 CDS YP_001462351.1 157155645 5586071 1254777..1256021 1 NC_009801.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1256021 lolE 5586071 lolE Escherichia coli E24377A outer membrane-specific lipoprotein transporter subunit LolE YP_001462351.1 1254777 D 331111 CDS YP_001462352.1 157158406 5588823 1256050..1256961 1 NC_009801.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1256961 nagK 5588823 nagK Escherichia coli E24377A N-acetyl-D-glucosamine kinase YP_001462352.1 1256050 D 331111 CDS YP_001462353.1 157155014 5590632 complement(1257937..1258725) 1 NC_009801.1 hypothetical protein 1258725 5590632 EcE24377A_1243 Escherichia coli E24377A hypothetical protein YP_001462353.1 1257937 R 331111 CDS YP_001462354.1 157155386 5589182 complement(1258722..1259183) 1 NC_009801.1 hypothetical protein 1259183 5589182 EcE24377A_1244 Escherichia coli E24377A hypothetical protein YP_001462354.1 1258722 R 331111 CDS YP_001462355.1 157157551 5586948 1259025..1259162 1 NC_009801.1 identified by glimmer; hypothetical protein 1259162 5586948 EcE24377A_1245 Escherichia coli E24377A hypothetical protein YP_001462355.1 1259025 D 331111 CDS YP_001462356.1 157158028 5590423 complement(1259241..1260287) 1 NC_009801.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein 1260287 potD 5590423 potD Escherichia coli E24377A spermidine/putrescine ABC transporter substrate-binding protein YP_001462356.1 1259241 R 331111 CDS YP_001462357.1 157158875 5588762 complement(1260284..1261078) 1 NC_009801.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1261078 potC 5588762 potC Escherichia coli E24377A spermidine/putrescine ABC transporter membrane protein YP_001462357.1 1260284 R 331111 CDS YP_001462358.1 157159388 5590340 complement(1262112..1263230) 1 NC_009801.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003; phage integrase 1263230 5590340 EcE24377A_1248 Escherichia coli E24377A phage integrase YP_001462358.1 1262112 R 331111 CDS YP_001462359.1 157155362 5586258 complement(1263199..1263468) 1 NC_009801.1 identified by similarity to SP:P27079; excisionase 1263468 5586258 EcE24377A_1249 Escherichia coli E24377A excisionase YP_001462359.1 1263199 R 331111 CDS YP_001462360.1 157158330 5590052 complement(1263530..1264297) 1 NC_009801.1 exonuclease 1264297 5590052 EcE24377A_1250 Escherichia coli E24377A exonuclease YP_001462360.1 1263530 R 331111 CDS YP_001462361.1 157156645 5586341 complement(1264375..1265907) 1 NC_009801.1 exonuclease 1265907 5586341 EcE24377A_1251 Escherichia coli E24377A exonuclease YP_001462361.1 1264375 R 331111 CDS YP_001462362.1 157154926 5587455 complement(1266001..1266192) 1 NC_009801.1 identified by similarity to GB:AAN79873.1; match to protein family HMM PF07358; hypothetical protein 1266192 5587455 EcE24377A_1252 Escherichia coli E24377A hypothetical protein YP_001462362.1 1266001 R 331111 CDS YP_001462363.1 157154851 5588049 complement(1266189..1266482) 1 NC_009801.1 identified by match to protein family HMM PF05358; DicB protein 1266482 5588049 EcE24377A_1253 Escherichia coli E24377A DicB protein YP_001462363.1 1266189 R 331111 CDS YP_001462364.1 157159144 5589298 1266941..1267150 1 NC_009801.1 identified by glimmer; hypothetical protein 1267150 5589298 EcE24377A_1254 Escherichia coli E24377A hypothetical protein YP_001462364.1 1266941 D 331111 CDS YP_001462365.1 157155289 5590743 complement(1267151..1267789) 1 NC_009801.1 identified by glimmer; hypothetical protein 1267789 5590743 EcE24377A_1255 Escherichia coli E24377A hypothetical protein YP_001462365.1 1267151 R 331111 CDS YP_001462366.1 157155803 5587659 complement(1267801..1268034) 1 NC_009801.1 identified by match to protein family HMM PF07151; hypothetical protein 1268034 5587659 EcE24377A_1256 Escherichia coli E24377A hypothetical protein YP_001462366.1 1267801 R 331111 CDS YP_001462367.1 157157946 5590385 complement(1268525..1268716) 1 NC_009801.1 identified by similarity to GB:AAK16987.1; hypothetical protein 1268716 5590385 EcE24377A_1257 Escherichia coli E24377A hypothetical protein YP_001462367.1 1268525 R 331111 CDS YP_001462368.1 157155981 5586021 1269506..1269931 1 NC_009801.1 identified by similarity to GB:AAN79880.1; match to protein family HMM PF06254; hypothetical protein 1269931 5586021 EcE24377A_1258 Escherichia coli E24377A hypothetical protein YP_001462368.1 1269506 D 331111 CDS YP_001462369.1 157157491 5588638 1269955..1270902 1 NC_009801.1 identified by similarity to SP:P03688; phage O family protein 1270902 5588638 EcE24377A_1259 Escherichia coli E24377A phage O family protein YP_001462369.1 1269955 D 331111 CDS YP_001462370.1 157157300 5586250 1270909..1271655 1 NC_009801.1 identified by similarity to SP:P0AEF0; match to protein family HMM PF01695; replication protein 1271655 5586250 EcE24377A_1260 Escherichia coli E24377A replication protein YP_001462370.1 1270909 D 331111 CDS YP_001462371.1 157158207 5590834 1271677..1272438 1 NC_009801.1 identified by similarity to GB:AAG56436.1; match to protein family HMM PF07789; hypothetical protein 1272438 5590834 EcE24377A_1261 Escherichia coli E24377A hypothetical protein YP_001462371.1 1271677 D 331111 CDS YP_001462372.1 157157659 5588178 1272454..1272876 1 NC_009801.1 identified by match to protein family HMM PF06163; hypothetical protein 1272876 5588178 EcE24377A_1262 Escherichia coli E24377A hypothetical protein YP_001462372.1 1272454 D 331111 CDS YP_001462373.1 157154943 5590027 1272879..1273223 1 NC_009801.1 identified by similarity to GB:BAB34936.1; hypothetical protein 1273223 5590027 EcE24377A_1263 Escherichia coli E24377A hypothetical protein YP_001462373.1 1272879 D 331111 CDS YP_001462374.1 157158248 5586872 complement(1273326..1273430) 1 NC_009801.1 identified by glimmer; hypothetical protein 1273430 5586872 EcE24377A_1264 Escherichia coli E24377A hypothetical protein YP_001462374.1 1273326 R 331111 CDS YP_001462375.1 157156609 5586421 1273395..1273817 1 NC_009801.1 hypothetical protein 1273817 5586421 EcE24377A_1265 Escherichia coli E24377A hypothetical protein YP_001462375.1 1273395 D 331111 CDS YP_001462376.1 157155003 5589991 1274711..1275766 1 NC_009801.1 identified by similarity to GB:AAZ88571.1; match to protein family HMM PF06914; hypothetical protein 1275766 5589991 EcE24377A_1266 Escherichia coli E24377A hypothetical protein YP_001462376.1 1274711 D 331111 CDS YP_001462377.1 157158638 5586592 1275767..1276132 1 NC_009801.1 identified by similarity to SP:Q9MCN8; match to protein family HMM PF05866; crossover junction endodeoxyribonuclease RusA-like protein 1276132 5586592 EcE24377A_1267 Escherichia coli E24377A crossover junction endodeoxyribonuclease RusA-like protein YP_001462377.1 1275767 D 331111 CDS YP_001462378.1 157159224 5585897 1276129..1276818 1 NC_009801.1 identified by match to protein family HMM PF06323; phage antitermination protein Q 1276818 5585897 EcE24377A_1268 Escherichia coli E24377A phage antitermination protein Q YP_001462378.1 1276129 D 331111 CDS YP_001462379.1 157159351 5586532 1276963..1277727 1 NC_009801.1 identified by match to protein family HMM PF00069; protein kinase domain-containing protein 1277727 5586532 EcE24377A_1269 Escherichia coli E24377A protein kinase domain-containing protein YP_001462379.1 1276963 D 331111 CDS YP_001462380.1 157157467 5585983 1277724..1278467 1 NC_009801.1 identified by glimmer; hypothetical protein 1278467 5585983 EcE24377A_1270 Escherichia coli E24377A hypothetical protein YP_001462380.1 1277724 D 331111 CDS YP_001462381.1 157157704 5588098 1278600..1278884 1 NC_009801.1 hypothetical protein 1278884 5588098 EcE24377A_1271 Escherichia coli E24377A hypothetical protein YP_001462381.1 1278600 D 331111 CDS YP_001462382.1 157156016 5586446 1279035..1280084 1 NC_009801.1 identified by match to protein family HMM PF01555; DNA methylase 1280084 5586446 EcE24377A_1272 Escherichia coli E24377A DNA methylase YP_001462382.1 1279035 D 331111 CDS YP_001462383.1 157155638 5590321 1280912..1281304 1 NC_009801.1 identified by similarity to GB:CAC83546.1; hypothetical protein 1281304 5590321 EcE24377A_1276 Escherichia coli E24377A hypothetical protein YP_001462383.1 1280912 D 331111 CDS YP_001462384.1 157159162 5589099 1281294..1281569 1 NC_009801.1 identified by similarity to GB:AAO06087.1; match to protein family HMM PF05449; phage holin 1281569 5589099 EcE24377A_1277 Escherichia coli E24377A phage holin YP_001462384.1 1281294 D 331111 CDS YP_001462385.1 157157446 5590608 1281572..1281949 1 NC_009801.1 hypothetical protein 1281949 5590608 EcE24377A_1278 Escherichia coli E24377A hypothetical protein YP_001462385.1 1281572 D 331111 CDS YP_001462386.1 157158088 5590386 1281957..1282061 1 NC_009801.1 identified by glimmer; hypothetical protein 1282061 5590386 EcE24377A_1279 Escherichia coli E24377A hypothetical protein YP_001462386.1 1281957 D 331111 CDS YP_001462387.1 157158120 5588783 1283046..1283210 1 NC_009801.1 lipoprotein 1283210 5588783 EcE24377A_1280 Escherichia coli E24377A lipoprotein YP_001462387.1 1283046 D 331111 CDS YP_001462388.1 157156752 5590277 1283292..1283846 1 NC_009801.1 identified by match to protein family HMM PF07471; phage DNA packaging protein Nu1 1283846 5590277 EcE24377A_1281 Escherichia coli E24377A phage DNA packaging protein Nu1 YP_001462388.1 1283292 D 331111 CDS YP_001462389.1 157154718 5586119 1283798..1284043 1 NC_009801.1 identified by match to protein family HMM PF06316; match to protein family HMM TIGR03304; entero Ail/Lom protein 1284043 5586119 EcE24377A_1282 Escherichia coli E24377A entero Ail/Lom protein YP_001462389.1 1283798 D 331111 CDS YP_001462390.1 157159373 5588402 1284108..1287521 1 NC_009801.1 identified by match to protein family HMM PF03335; match to protein family HMM PF03406; match to protein family HMM PF07484; match to protein family HMM PF08400; phage tail domain-containing protein 1287521 5588402 EcE24377A_1284 Escherichia coli E24377A phage tail domain-containing protein YP_001462390.1 1284108 D 331111 CDS YP_001462391.1 157157597 5589065 1287521..1288105 1 NC_009801.1 identified by similarity to SP:P03740; match to protein family HMM PF02413; tail fiber assembly protein 1288105 5589065 EcE24377A_1285 Escherichia coli E24377A tail fiber assembly protein YP_001462391.1 1287521 D 331111 CDS YP_001462392.1 157155504 5587959 complement(1288160..1288816) 1 NC_009801.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; hypothetical protein 1288816 5587959 EcE24377A_1286 Escherichia coli E24377A hypothetical protein YP_001462392.1 1288160 R 331111 CDS YP_001462393.1 157157332 5590792 1288885..1289151 1 NC_009801.1 identified by glimmer; hypothetical protein 1289151 5590792 EcE24377A_1287 Escherichia coli E24377A hypothetical protein YP_001462393.1 1288885 D 331111 CDS YP_001462394.1 157157953 5588738 complement(1289384..1290247) 1 NC_009801.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1290247 potB 5588738 potB Escherichia coli E24377A spermidine/putrescine ABC transporter membrane protein YP_001462394.1 1289384 R 331111 CDS YP_001462395.1 157156235 5589414 complement(1290231..1291367) 1 NC_009801.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 1291367 potA 5589414 potA Escherichia coli E24377A putrescine/spermidine ABC transporter ATPase YP_001462395.1 1290231 R 331111 CDS YP_001462396.1 157156938 5586690 1291617..1292846 1 NC_009801.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1292846 pepT 5586690 pepT Escherichia coli E24377A peptidase T YP_001462396.1 1291617 D 331111 CDS YP_001462397.1 157155178 5589440 complement(1292992..1294113) 1 NC_009801.1 identified by match to protein family HMM PF08007; cupin family protein 1294113 5589440 EcE24377A_1291 Escherichia coli E24377A cupin family protein YP_001462397.1 1292992 R 331111 CDS YP_001462398.1 157155874 5588755 complement(1294189..1295649) 1 NC_009801.1 identified by similarity to SP:P23837; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF08918; sensor protein PhoQ 1295649 phoQ 5588755 phoQ Escherichia coli E24377A sensor protein PhoQ YP_001462398.1 1294189 R 331111 CDS YP_001462399.1 157159002 5589859 complement(1295649..1296320) 1 NC_009801.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 1296320 phoP 5589859 phoP Escherichia coli E24377A DNA-binding transcriptional regulator PhoP YP_001462399.1 1295649 R 331111 CDS YP_001462400.1 157154805 5588089 complement(1296488..1297858) 1 NC_009801.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1297858 purB 5588089 purB Escherichia coli E24377A adenylosuccinate lyase YP_001462400.1 1296488 R 331111 CDS YP_001462401.1 157156571 5585956 complement(1297862..1298503) 1 NC_009801.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1298503 5585956 EcE24377A_1295 Escherichia coli E24377A hypothetical protein YP_001462401.1 1297862 R 331111 CDS YP_001462402.1 157156703 5588042 complement(1298539..1299645) 1 NC_009801.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1299645 mnmA 5588042 mnmA Escherichia coli E24377A tRNA-specific 2-thiouridylase MnmA YP_001462402.1 1298539 R 331111 CDS YP_001462403.1 157156203 5590863 complement(1299699..1300160) 1 NC_009801.1 identified by match to protein family HMM PF00293; NUDIX family hydrolase 1300160 5590863 EcE24377A_1297 Escherichia coli E24377A NUDIX family hydrolase YP_001462403.1 1299699 R 331111 CDS YP_001462404.1 157158295 5588029 complement(1300170..1300823) 1 NC_009801.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E 1300823 rluE 5588029 rluE Escherichia coli E24377A 23S rRNA pseudouridine synthase E YP_001462404.1 1300170 R 331111 CDS YP_001462405.1 157155568 5586891 1300995..1302245 1 NC_009801.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1302245 icd 5586891 icd Escherichia coli E24377A isocitrate dehydrogenase YP_001462405.1 1300995 D 331111 CDS YP_001462406.1 157157286 5589696 complement(1303367..1303771) 1 NC_009801.1 identified by match to protein family HMM PF07166; hypothetical protein 1303771 5589696 EcE24377A_1300 Escherichia coli E24377A hypothetical protein YP_001462406.1 1303367 R 331111 CDS YP_001462407.1 157158661 5590150 complement(1303992..1304723) 1 NC_009801.1 identified by similarity to SP:P33358; match to protein family HMM PF00376; transcriptional regulator mlrA-like protein 1304723 5590150 EcE24377A_1301 Escherichia coli E24377A transcriptional regulator mlrA-like protein YP_001462407.1 1303992 R 331111 CDS YP_001462408.1 157155353 5587736 complement(1304633..1304785) 1 NC_009801.1 identified by glimmer; hypothetical protein 1304785 5587736 EcE24377A_1302 Escherichia coli E24377A hypothetical protein YP_001462408.1 1304633 R 331111 CDS YP_001462409.1 157154832 5590123 complement(1304928..1306139) 1 NC_009801.1 identified by match to protein family HMM PF00563; match to protein family HMM PF04940; BLUF/cyclic diguanylate phosphodiesterase domain-containing protein 1306139 5590123 EcE24377A_1303 Escherichia coli E24377A BLUF/cyclic diguanylate phosphodiesterase domain-containing protein YP_001462409.1 1304928 R 331111 CDS YP_001462410.1 157158780 5586362 1306732..1307004 1 NC_009801.1 identified by similarity to SP:P75992; hypothetical protein 1307004 5586362 EcE24377A_1304 Escherichia coli E24377A hypothetical protein YP_001462410.1 1306732 D 331111 CDS YP_001462411.1 157155634 5587007 1307033..1307299 1 NC_009801.1 hypothetical protein 1307299 5587007 EcE24377A_1305 Escherichia coli E24377A hypothetical protein YP_001462411.1 1307033 D 331111 CDS YP_001462412.1 157159276 5589761 1307412..1307660 1 NC_009801.1 hypothetical protein 1307660 5589761 EcE24377A_1306 Escherichia coli E24377A hypothetical protein YP_001462412.1 1307412 D 331111 CDS YP_001462413.1 157157600 5588131 1307950..1309515 1 NC_009801.1 identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase domain-containing protein 1309515 5588131 EcE24377A_1307 Escherichia coli E24377A cyclic diguanylate phosphodiesterase domain-containing protein YP_001462413.1 1307950 D 331111 CDS YP_001462414.1 157157960 5590369 1309647..1309865 1 NC_009801.1 ymgF; hypothetical protein 1309865 5590369 EcE24377A_1308 Escherichia coli E24377A hypothetical protein YP_001462414.1 1309647 D 331111 CDS YP_001462415.1 157156332 5586296 1309958..1310101 1 NC_009801.1 identified by glimmer; hypothetical protein 1310101 5586296 EcE24377A_1309 Escherichia coli E24377A hypothetical protein YP_001462415.1 1309958 D 331111 CDS YP_001462416.1 157156097 5590019 1310265..1310474 1 NC_009801.1 identified by glimmer; hypothetical protein 1310474 5590019 EcE24377A_1310 Escherichia coli E24377A hypothetical protein YP_001462416.1 1310265 D 331111 CDS YP_001462417.1 157156794 5586163 1310730..1310870 1 NC_009801.1 identified by glimmer; hypothetical protein 1310870 5586163 EcE24377A_1311 Escherichia coli E24377A hypothetical protein YP_001462417.1 1310730 D 331111 CDS YP_001462418.1 157154735 5588165 1311992..1312912 1 NC_009801.1 identified by match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR03304; autotransporter (AT) family porin 1312912 5588165 EcE24377A_1312 Escherichia coli E24377A autotransporter (AT) family porin YP_001462418.1 1311992 D 331111 CDS YP_001462419.1 157155388 5590446 complement(1312969..1313298) 1 NC_009801.1 ymgD; identified by glimmer; hypothetical protein 1313298 5590446 EcE24377A_1313 Escherichia coli E24377A hypothetical protein YP_001462419.1 1312969 R 331111 CDS YP_001462420.1 157156205 5587373 complement(1313308..1313652) 1 NC_009801.1 identified by similarity to GB:ABB13223.1; hypothetical protein 1313652 5587373 EcE24377A_1314 Escherichia coli E24377A hypothetical protein YP_001462420.1 1313308 R 331111 CDS YP_001462421.1 157156912 5587414 complement(1313654..1313827) 1 NC_009801.1 identified by glimmer; hypothetical protein 1313827 5587414 EcE24377A_1315 Escherichia coli E24377A hypothetical protein YP_001462421.1 1313654 R 331111 CDS YP_001462422.1 157156198 5590156 1314074..1314193 1 NC_009801.1 identified by glimmer; hypothetical protein 1314193 5590156 EcE24377A_1316 Escherichia coli E24377A hypothetical protein YP_001462422.1 1314074 D 331111 CDS YP_001462423.1 157156771 5588700 1314162..1314572 1 NC_009801.1 identified by glimmer; hypothetical protein 1314572 5588700 EcE24377A_1317 Escherichia coli E24377A hypothetical protein YP_001462423.1 1314162 D 331111 CDS YP_001462424.1 157154772 5588623 complement(1314944..1315210) 1 NC_009801.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 1315210 minE 5588623 minE Escherichia coli E24377A cell division topological specificity factor MinE YP_001462424.1 1314944 R 331111 CDS YP_001462425.1 157155382 5589493 complement(1315214..1316026) 1 NC_009801.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD 1316026 minD 5589493 minD Escherichia coli E24377A cell division inhibitor MinD YP_001462425.1 1315214 R 331111 CDS YP_001462426.1 157158782 5589377 complement(1316050..1316745) 1 NC_009801.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 1316745 minC 5589377 minC Escherichia coli E24377A septum formation inhibitor YP_001462426.1 1316050 R 331111 CDS YP_001462427.1 157159409 5587207 1317265..1317633 1 NC_009801.1 identified by match to protein family HMM PF05666; fels-1 prophage protein 1317633 5587207 EcE24377A_1321 Escherichia coli E24377A fels-1 prophage protein YP_001462427.1 1317265 D 331111 CDS YP_001462428.1 157155831 5589714 complement(1317753..1318154) 1 NC_009801.1 identified by match to protein family HMM PF04151; pre-peptidase C-terminal domain-containing protein 1318154 5589714 EcE24377A_1322 Escherichia coli E24377A pre-peptidase C-terminal domain-containing protein YP_001462428.1 1317753 R 331111 CDS YP_001462429.1 157155276 5587344 1318396..1318689 1 NC_009801.1 identified by match to protein family HMM PF05166; hypothetical protein 1318689 5587344 EcE24377A_1323 Escherichia coli E24377A hypothetical protein YP_001462429.1 1318396 D 331111 CDS YP_001462430.1 157159100 5587592 1318761..1319420 1 NC_009801.1 identified by match to protein family HMM PF01557; hypothetical protein 1319420 5587592 EcE24377A_1324 Escherichia coli E24377A hypothetical protein YP_001462430.1 1318761 D 331111 CDS YP_001462431.1 157158771 5586591 1319497..1319958 1 NC_009801.1 identified by match to protein family HMM PF03692; hypothetical protein 1319958 5586591 EcE24377A_1325 Escherichia coli E24377A hypothetical protein YP_001462431.1 1319497 D 331111 CDS YP_001462432.1 157156225 5588214 complement(1321212..1321322) 1 NC_009801.1 identified by glimmer; hypothetical protein 1321322 5588214 EcE24377A_1327 Escherichia coli E24377A hypothetical protein YP_001462432.1 1321212 R 331111 CDS YP_001462433.1 157159399 5586979 1321448..1321867 1 NC_009801.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1321867 umuD 5586979 umuD Escherichia coli E24377A DNA polymerase V subunit UmuD YP_001462433.1 1321448 D 331111 CDS YP_001462434.1 157155325 5590061 1321867..1323135 1 NC_009801.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1323135 umuC 5590061 umuC Escherichia coli E24377A DNA polymerase V subunit UmuC YP_001462434.1 1321867 D 331111 CDS YP_001462435.1 157158035 5590117 complement(1323181..1323711) 1 NC_009801.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1323711 dsbB 5590117 dsbB Escherichia coli E24377A disulfide bond formation protein B YP_001462435.1 1323181 R 331111 CDS YP_001462436.1 157158871 5587572 complement(1323857..1325398) 1 NC_009801.1 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 1325398 nhaB 5587572 nhaB Escherichia coli E24377A sodium/proton antiporter YP_001462436.1 1323857 R 331111 CDS YP_001462437.1 157159010 5587451 1325620..1326339 1 NC_009801.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1326339 fadR 5587451 fadR Escherichia coli E24377A fatty acid metabolism regulator YP_001462437.1 1325620 D 331111 CDS YP_001462438.1 157155859 5588943 complement(1326391..1327923) 1 NC_009801.1 identified by match to protein family HMM PF04293; SpoVR family protein 1327923 5588943 EcE24377A_1333 Escherichia coli E24377A SpoVR family protein YP_001462438.1 1326391 R 331111 CDS YP_001462439.1 157157970 5587987 1328253..1329551 1 NC_009801.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1329551 dadA 5587987 dadA Escherichia coli E24377A D-amino acid dehydrogenase small subunit YP_001462439.1 1328253 D 331111 CDS YP_001462440.1 157157280 5590763 1329561..1330631 1 NC_009801.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1330631 dadX 5590763 dadX Escherichia coli E24377A alanine racemase YP_001462440.1 1329561 D 331111 CDS YP_001462441.1 157155249 5589723 complement(1331017..1332753) 1 NC_009801.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 1332753 cvrA 5589723 cvrA Escherichia coli E24377A potassium/proton antiporter YP_001462441.1 1331017 R 331111 CDS YP_001462442.1 157155614 5590451 complement(1332848..1333762) 1 NC_009801.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A 1333762 ldcA 5590451 ldcA Escherichia coli E24377A L,D-carboxypeptidase A YP_001462442.1 1332848 R 331111 CDS YP_001462443.1 157158317 5586066 1333748..1334473 1 NC_009801.1 identified by similarity to SP:P76009; match to protein family HMM PF01464; membrane-bound lytic murein transglycosylase E 1334473 mltE 5586066 mltE Escherichia coli E24377A membrane-bound lytic murein transglycosylase E YP_001462443.1 1333748 D 331111 CDS YP_001462444.1 157159385 5587459 complement(1334475..1335209) 1 NC_009801.1 identified by match to protein family HMM PF07238; match to protein family HMM PF07317; type IV pilus assembly protein PilZ 1335209 5587459 EcE24377A_1339 Escherichia coli E24377A type IV pilus assembly protein PilZ YP_001462444.1 1334475 R 331111 CDS YP_001462445.1 157157734 5588689 1335410..1335664 1 NC_009801.1 identified by match to protein family HMM PF04226; transglycosylase-associated protein 1335664 5588689 EcE24377A_1341 Escherichia coli E24377A transglycosylase-associated protein YP_001462445.1 1335410 D 331111 CDS YP_001462446.1 157157294 5590835 complement(1335464..1335733) 1 NC_009801.1 identified by similarity to GB:AAT83486.1; hypothetical protein 1335733 5590835 EcE24377A_1340 Escherichia coli E24377A hypothetical protein YP_001462446.1 1335464 R 331111 CDS YP_001462447.1 157158329 5586909 1335842..1336282 1 NC_009801.1 identified by similarity to GB:ABB66472.1; hypothetical protein 1336282 5586909 EcE24377A_1342 Escherichia coli E24377A hypothetical protein YP_001462447.1 1335842 D 331111 CDS YP_001462448.1 157159159 5586340 complement(1336361..1338058) 1 NC_009801.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase 1338058 treA 5586340 treA Escherichia coli E24377A trehalase YP_001462448.1 1336361 R 331111 CDS YP_001462449.1 157157322 5587051 complement(1338378..1339796) 1 NC_009801.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit DhaM 1339796 dhaM 5587051 dhaM Escherichia coli E24377A dihydroxyacetone kinase subunit DhaM YP_001462449.1 1338378 R 331111 CDS YP_001462450.1 157155726 5588009 complement(1339807..1340439) 1 NC_009801.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL 1340439 5588009 EcE24377A_1345 Escherichia coli E24377A dihydroxyacetone kinase subunit DhaL YP_001462450.1 1339807 R 331111 CDS YP_001462451.1 157158476 5587160 complement(1340450..1341520) 1 NC_009801.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 1341520 dhaK 5587160 dhaK Escherichia coli E24377A dihydroxyacetone kinase subunit DhaK YP_001462451.1 1340450 R 331111 CDS YP_001462452.1 157159109 5585922 1341748..1343667 1 NC_009801.1 Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1343667 dhaR 5585922 dhaR Escherichia coli E24377A DNA-binding transcriptional regulator DhaR YP_001462452.1 1341748 D 331111 CDS YP_001462453.1 157157255 5587909 complement(1343767..1346652) 1 NC_009801.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; outer membrane autotransporter 1346652 5587909 EcE24377A_1348 Escherichia coli E24377A outer membrane autotransporter YP_001462453.1 1343767 R 331111 CDS YP_001462454.1 157157620 5588419 1346997..1347200 1 NC_009801.1 identified by similarity to GB:AAZ88642.1; hypothetical protein 1347200 5588419 EcE24377A_1349 Escherichia coli E24377A hypothetical protein YP_001462454.1 1346997 D 331111 CDS YP_001462455.1 157157840 5586716 complement(1347493..1348584) 1 NC_009801.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1348584 engD 5586716 engD Escherichia coli E24377A GTP-dependent nucleic acid-binding protein EngD YP_001462455.1 1347493 R 331111 CDS YP_001462456.1 157156333 5589295 complement(1348701..1349285) 1 NC_009801.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1349285 pth 5589295 pth Escherichia coli E24377A peptidyl-tRNA hydrolase YP_001462456.1 1348701 R 331111 CDS YP_001462457.1 157155770 5588313 1349563..1349841 1 NC_009801.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1349841 5588313 EcE24377A_1352 Escherichia coli E24377A hypothetical protein YP_001462457.1 1349563 D 331111 CDS YP_001462458.1 157158365 5586517 complement(1349896..1351548) 1 NC_009801.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM 1351548 ychM 5586517 ychM Escherichia coli E24377A sulfate transporter YchM YP_001462458.1 1349896 R 331111 CDS YP_001462459.1 157156600 5586041 complement(1351481..1351603) 1 NC_009801.1 identified by glimmer; hypothetical protein 1351603 5586041 EcE24377A_1354 Escherichia coli E24377A hypothetical protein YP_001462459.1 1351481 R 331111 CDS YP_001462460.1 157156694 5589995 complement(1351700..1352647) 1 NC_009801.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1352647 prs 5589995 prs Escherichia coli E24377A ribose-phosphate pyrophosphokinase YP_001462460.1 1351700 R 331111 CDS YP_001462461.1 157157479 5587942 complement(1352798..1353649) 1 NC_009801.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1353649 ipk 5587942 ipk Escherichia coli E24377A 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_001462461.1 1352798 R 331111 CDS YP_001462462.1 157158274 5589442 complement(1353649..1354272) 1 NC_009801.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; molecular chaperone LolB 1354272 lolB 5589442 lolB Escherichia coli E24377A molecular chaperone LolB YP_001462462.1 1353649 R 331111 CDS YP_001462463.1 157158798 5586780 1354486..1355742 1 NC_009801.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1355742 hemA 5586780 hemA Escherichia coli E24377A glutamyl-tRNA reductase YP_001462463.1 1354486 D 331111 CDS YP_001462464.1 157158410 5588597 1355784..1356866 1 NC_009801.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1356866 prfA 5588597 prfA Escherichia coli E24377A peptide chain release factor 1 YP_001462464.1 1355784 D 331111 CDS YP_001462465.1 157156593 5589355 1356866..1357699 1 NC_009801.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1357699 hemK 5589355 hemK Escherichia coli E24377A N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_001462465.1 1356866 D 331111 CDS YP_001462466.1 157154746 5589103 1357696..1358088 1 NC_009801.1 identified by match to protein family HMM PF04247; transcriptional regulator 1358088 5589103 EcE24377A_1361 Escherichia coli E24377A transcriptional regulator YP_001462466.1 1357696 D 331111 CDS YP_001462467.1 157156818 5586751 1358092..1358901 1 NC_009801.1 transcriptional regulator 1358901 sirB1 5586751 sirB1 Escherichia coli E24377A transcriptional regulator YP_001462467.1 1358092 D 331111 CDS YP_001462468.1 157158072 5586581 1358937..1359791 1 NC_009801.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1359791 kdsA 5586581 kdsA Escherichia coli E24377A 2-dehydro-3-deoxyphosphooctonate aldolase YP_001462468.1 1358937 D 331111 CDS YP_001462469.1 157156804 5587576 complement(1359940..1360074) 1 NC_009801.1 identified by similarity to GB:AAZ88629.1; hypothetical protein 1360074 5587576 EcE24377A_1364 Escherichia coli E24377A hypothetical protein YP_001462469.1 1359940 R 331111 CDS YP_001462470.1 157155447 5587705 complement(1360475..1360609) 1 NC_009801.1 identified by similarity to GB:AAZ88629.1; hypothetical protein 1360609 5587705 EcE24377A_1365 Escherichia coli E24377A hypothetical protein YP_001462470.1 1360475 R 331111 CDS YP_001462471.1 157157160 5588218 complement(1360988..1362088) 1 NC_009801.1 identified by match to protein family HMM PF01699; match to protein family HMM TIGR00846; calcium/sodium:proton antiporter 1362088 5588218 EcE24377A_1366 Escherichia coli E24377A calcium/sodium:proton antiporter YP_001462471.1 1360988 R 331111 CDS YP_001462472.1 157158720 5588611 1362358..1362588 1 NC_009801.1 in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1362588 chaB 5588611 chaB Escherichia coli E24377A cation transport regulator YP_001462472.1 1362358 D 331111 CDS YP_001462473.1 157159256 5588676 1362725..1363441 1 NC_009801.1 identified by match to protein family HMM PF04752; chaC protein 1363441 5588676 EcE24377A_1368 Escherichia coli E24377A chaC protein YP_001462473.1 1362725 D 331111 CDS YP_001462474.1 157155825 5587044 complement(1363485..1363838) 1 NC_009801.1 identified by match to protein family HMM PF02635; dsrE family protein 1363838 5587044 EcE24377A_1369 Escherichia coli E24377A dsrE family protein YP_001462474.1 1363485 R 331111 CDS YP_001462475.1 157155078 5590104 1364023..1365417 1 NC_009801.1 hypothetical protein 1365417 5590104 EcE24377A_1370 Escherichia coli E24377A hypothetical protein YP_001462475.1 1364023 D 331111 CDS YP_001462476.1 157155985 5588243 complement(1365418..1366068) 1 NC_009801.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL 1366068 narL 5588243 narL Escherichia coli E24377A transcriptional regulator NarL YP_001462476.1 1365418 R 331111 CDS YP_001462477.1 157156669 5588585 complement(1366061..1367857) 1 NC_009801.1 identified by similarity to SP:P10956; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730; nitrate/nitrite sensor protein NarX 1367857 narX 5588585 narX Escherichia coli E24377A nitrate/nitrite sensor protein NarX YP_001462477.1 1366061 R 331111 CDS YP_001462478.1 157157893 5588955 1367883..1368101 1 NC_009801.1 identified by glimmer; hypothetical protein 1368101 5588955 EcE24377A_1373 Escherichia coli E24377A hypothetical protein YP_001462478.1 1367883 D 331111 CDS YP_001462479.1 157157386 5587489 1368196..1369581 1 NC_009801.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00886; nitrite extrusion protein 1 1369581 narK 5587489 narK Escherichia coli E24377A nitrite extrusion protein 1 YP_001462479.1 1368196 D 331111 CDS YP_001462480.1 157155191 5589837 1370102..1373845 1 NC_009801.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; nitrate reductase subunit alpha 1373845 narG 5589837 narG Escherichia coli E24377A nitrate reductase subunit alpha YP_001462480.1 1370102 D 331111 CDS YP_001462481.1 157159405 5588229 1373842..1375380 1 NC_009801.1 identified by similarity to SP:P11349; match to protein family HMM PF00037; match to protein family HMM TIGR01660; nitrate reductase subunit beta 1375380 narH 5588229 narH Escherichia coli E24377A nitrate reductase subunit beta YP_001462481.1 1373842 D 331111 CDS YP_001462482.1 157156515 5589909 1375377..1376087 1 NC_009801.1 identified by similarity to SP:P0AF26; match to protein family HMM PF02613; match to protein family HMM TIGR00684; nitrate reductase molybdenum cofactor assembly chaperone 1376087 narJ 5589909 narJ Escherichia coli E24377A nitrate reductase molybdenum cofactor assembly chaperone YP_001462482.1 1375377 D 331111 CDS YP_001462483.1 157155384 5587216 1376087..1376764 1 NC_009801.1 identified by similarity to SP:P11350; match to protein family HMM PF02665; match to protein family HMM TIGR00351; respiratory nitrate reductase subunit gamma 1376764 narI1 5587216 narI1 Escherichia coli E24377A respiratory nitrate reductase subunit gamma YP_001462483.1 1376087 D 331111 CDS YP_001462484.1 157156756 5590220 complement(1377844..1378686) 1 NC_009801.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1378686 purU 5590220 purU Escherichia coli E24377A formyltetrahydrofolate deformylase YP_001462484.1 1377844 R 331111 CDS YP_001462485.1 157155665 5585942 complement(1378736..1379194) 1 NC_009801.1 identified by match to protein family HMM PF02810; hypothetical protein 1379194 5585942 EcE24377A_1382 Escherichia coli E24377A hypothetical protein YP_001462485.1 1378736 R 331111 CDS YP_001462486.1 157157525 5587745 1379307..1380212 1 NC_009801.1 identified by match to protein family HMM PF01734; hypothetical protein 1380212 5587745 EcE24377A_1383 Escherichia coli E24377A hypothetical protein YP_001462486.1 1379307 D 331111 CDS YP_001462487.1 157156877 5589553 1380304..1381317 1 NC_009801.1 identified by match to protein family HMM PF00072; response regulator of RpoS 1381317 5589553 EcE24377A_1384 Escherichia coli E24377A response regulator of RpoS YP_001462487.1 1380304 D 331111 CDS YP_001462488.1 157157142 5586206 1381519..1382427 1 NC_009801.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 1382427 galU 5586206 galU Escherichia coli E24377A UTP-glucose-1-phosphate uridylyltransferase YP_001462488.1 1381519 D 331111 CDS YP_001462489.1 157157780 5589795 complement(1382571..1382984) 1 NC_009801.1 identified by similarity to SP:P0ACF8; match to protein family HMM PF00816; global DNA-binding transcriptional dual regulator H-NS 1382984 hns 5589795 hns Escherichia coli E24377A global DNA-binding transcriptional dual regulator H-NS YP_001462489.1 1382571 R 331111 CDS YP_001462490.1 157159009 5588386 1383589..1384206 1 NC_009801.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1384206 tdk 5588386 tdk Escherichia coli E24377A thymidine kinase YP_001462490.1 1383589 D 331111 CDS YP_001462491.1 157155679 5587841 complement(1385501..1388182) 1 NC_009801.1 identified by similarity to SP:P0A9Q7; match to protein family HMM PF00171; match to protein family HMM PF00465; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1388182 adhE 5587841 adhE Escherichia coli E24377A bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_001462491.1 1385501 R 331111 CDS YP_001462492.1 157157980 5589806 1388659..1389306 1 NC_009801.1 identified by match to protein family HMM PF01914; match to protein family HMM TIGR00427; hypothetical protein 1389306 5589806 EcE24377A_1390 Escherichia coli E24377A hypothetical protein YP_001462492.1 1388659 D 331111 CDS YP_001462493.1 157157312 5586032 1390044..1391675 1 NC_009801.1 identified by match to protein family HMM PF00496; oligopeptide ABC transporter periplasmic oligopeptide-binding protein 1391675 oppA 5586032 oppA Escherichia coli E24377A oligopeptide ABC transporter periplasmic oligopeptide-binding protein YP_001462493.1 1390044 D 331111 CDS YP_001462494.1 157156245 5585935 1391761..1392681 1 NC_009801.1 identified by match to protein family HMM PF00528; oligopeptide transporter permease 1392681 oppB 5585935 oppB Escherichia coli E24377A oligopeptide transporter permease YP_001462494.1 1391761 D 331111 CDS YP_001462495.1 157157719 5587124 1392696..1393604 1 NC_009801.1 identified by match to protein family HMM PF00528; oligopeptide ABC transporter permease OppC 1393604 oppC 5587124 oppC Escherichia coli E24377A oligopeptide ABC transporter permease OppC YP_001462495.1 1392696 D 331111 CDS YP_001462496.1 157156418 5590628 1393616..1394629 1 NC_009801.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; oligopeptide ABC transporter ATP-binding protein 1394629 oppD 5590628 oppD Escherichia coli E24377A oligopeptide ABC transporter ATP-binding protein YP_001462496.1 1393616 D 331111 CDS YP_001462497.1 157157088 5588846 1394626..1395630 1 NC_009801.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; oligopeptide ABC transporter ATP-binding protein OppF 1395630 oppF 5588846 oppF Escherichia coli E24377A oligopeptide ABC transporter ATP-binding protein OppF YP_001462497.1 1394626 D 331111 CDS YP_001462498.1 157155070 5590583 complement(1395683..1396012) 1 NC_009801.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1396012 5590583 EcE24377A_1396 Escherichia coli E24377A dsDNA-mimic protein YP_001462498.1 1395683 R 331111 CDS YP_001462499.1 157159055 5587435 complement(1396047..1397507) 1 NC_009801.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 1397507 cls 5587435 cls Escherichia coli E24377A cardiolipin synthetase YP_001462499.1 1396047 R 331111 CDS YP_001462500.1 157159270 5586491 complement(1397878..1399131) 1 NC_009801.1 identified by similarity to SP:P31069; match to protein family HMM PF02254; match to protein family HMM PF07885; voltage-gated potassium channel 1399131 kch 5586491 kch Escherichia coli E24377A voltage-gated potassium channel YP_001462500.1 1397878 R 331111 CDS YP_001462501.1 157157428 5589592 complement(1399430..1399726) 1 NC_009801.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein 1399726 5589592 EcE24377A_1399 Escherichia coli E24377A hypothetical protein YP_001462501.1 1399430 R 331111 CDS YP_001462502.1 157158217 5588372 1401710..1402378 1 NC_009801.1 phage N-6-adenine-methyltransferase 1402378 5588372 EcE24377A_1400 Escherichia coli E24377A phage N-6-adenine-methyltransferase YP_001462502.1 1401710 D 331111 CDS YP_001462503.1 157156044 5587836 1402742..1403734 1 NC_009801.1 identified by similarity to GB:AAZ87752.1; hypothetical protein 1403734 5587836 EcE24377A_1401 Escherichia coli E24377A hypothetical protein YP_001462503.1 1402742 D 331111 CDS YP_001462504.1 157156553 5585943 1404867..1405076 1 NC_009801.1 identified by glimmer; hypothetical protein 1405076 5585943 EcE24377A_1402 Escherichia coli E24377A hypothetical protein YP_001462504.1 1404867 D 331111 CDS YP_001462505.1 157156543 5587719 1406063..1406773 1 NC_009801.1 hypothetical protein 1406773 5587719 EcE24377A_1403 Escherichia coli E24377A hypothetical protein YP_001462505.1 1406063 D 331111 CDS YP_001462506.1 157157072 5586470 1407125..1409257 1 NC_009801.1 identified by match to protein family HMM TIGR02675; hypothetical protein 1409257 5586470 EcE24377A_1404 Escherichia coli E24377A hypothetical protein YP_001462506.1 1407125 D 331111 CDS YP_001462507.1 157156436 5589032 1409617..1410006 1 NC_009801.1 identified by match to protein family HMM PF01527; IS66 family orf1 1410006 5589032 EcE24377A_1405 Escherichia coli E24377A IS66 family orf1 YP_001462507.1 1409617 D 331111 CDS YP_001462508.1 157158138 5590001 1410003..1410350 1 NC_009801.1 identified by match to protein family HMM PF05717; IS66 family orf2 1410350 5590001 EcE24377A_1406 Escherichia coli E24377A IS66 family orf2 YP_001462508.1 1410003 D 331111 CDS YP_001462509.1 157157306 5588358 1410400..1411938 1 NC_009801.1 identified by match to protein family HMM PF03050; IS66 family transposase 1411938 5588358 EcE24377A_1407 Escherichia coli E24377A IS66 family transposase YP_001462509.1 1410400 D 331111 CDS YP_001462510.1 157159212 5588511 1411961..1412644 1 NC_009801.1 hypothetical protein 1412644 5588511 EcE24377A_1408 Escherichia coli E24377A hypothetical protein YP_001462510.1 1411961 D 331111 CDS YP_001462511.1 157158350 5587462 complement(1412677..1414197) 1 NC_009801.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508; recombinase 1414197 5587462 EcE24377A_1409 Escherichia coli E24377A recombinase YP_001462511.1 1412677 R 331111 CDS YP_001462512.1 157155811 5586976 1414288..1415007 1 NC_009801.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter 1415007 tonB 5586976 tonB Escherichia coli E24377A transporter YP_001462512.1 1414288 D 331111 CDS YP_001462513.1 157155297 5586239 complement(1415047..1415445) 1 NC_009801.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase of proteins; acyl-CoA thioester hydrolase 1415445 yciA 5586239 yciA Escherichia coli E24377A acyl-CoA thioester hydrolase YP_001462513.1 1415047 R 331111 CDS YP_001462514.1 157158909 5588538 complement(1415550..1416089) 1 NC_009801.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1416089 ispZ 5588538 ispZ Escherichia coli E24377A intracellular septation protein A YP_001462514.1 1415550 R 331111 CDS YP_001462515.1 157158416 5589338 complement(1416119..1416862) 1 NC_009801.1 identified by match to protein family HMM PF06790; hypothetical protein 1416862 5589338 EcE24377A_1413 Escherichia coli E24377A hypothetical protein YP_001462515.1 1416119 R 331111 CDS YP_001462516.1 157157791 5589666 1417219..1417857 1 NC_009801.1 receptor for colicin S4; outer membrane protein W 1417857 ompW 5589666 ompW Escherichia coli E24377A outer membrane protein W YP_001462516.1 1417219 D 331111 CDS YP_001462517.1 157157141 5587807 complement(1417903..1419033) 1 NC_009801.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003; phage integrase site specific recombinase 1419033 5587807 EcE24377A_1415 Escherichia coli E24377A phage integrase site specific recombinase YP_001462517.1 1417903 R 331111 CDS YP_001462518.1 157155450 5589794 complement(1419324..1421795) 1 NC_009801.1 identified by match to protein family HMM PF00929; exonuclease 1421795 5589794 EcE24377A_1416 Escherichia coli E24377A exonuclease YP_001462518.1 1419324 R 331111 CDS YP_001462519.1 157154767 5586674 1421767..1421874 1 NC_009801.1 identified by glimmer; hypothetical protein 1421874 5586674 EcE24377A_1417 Escherichia coli E24377A hypothetical protein YP_001462519.1 1421767 D 331111 CDS YP_001462520.1 157159414 5588159 complement(1421875..1422078) 1 NC_009801.1 identified by match to protein family HMM PF07358; hypothetical protein 1422078 5588159 EcE24377A_1418 Escherichia coli E24377A hypothetical protein YP_001462520.1 1421875 R 331111 CDS YP_001462521.1 157158740 5586024 complement(1422274..1423128) 1 NC_009801.1 identified by match to protein family HMM TIGR02681; Rha family phage regulatory protein 1423128 5586024 EcE24377A_1419 Escherichia coli E24377A Rha family phage regulatory protein YP_001462521.1 1422274 R 331111 CDS YP_001462522.1 157158109 5588109 complement(1424416..1424562) 1 NC_009801.1 identified by similarity to GB:CAD05612.1; hypothetical protein 1424562 5588109 EcE24377A_1420 Escherichia coli E24377A hypothetical protein YP_001462522.1 1424416 R 331111 CDS YP_001462523.1 157157426 5590378 complement(1424564..1424812) 1 NC_009801.1 identified by match to protein family HMM PF07151; hypothetical protein 1424812 5590378 EcE24377A_1421 Escherichia coli E24377A hypothetical protein YP_001462523.1 1424564 R 331111 CDS YP_001462524.1 157157452 5588202 1425368..1425622 1 NC_009801.1 identified by similarity to SP:P06965; DNA-binding transcriptional regulator DicC 1425622 5588202 EcE24377A_1422 Escherichia coli E24377A DNA-binding transcriptional regulator DicC YP_001462524.1 1425368 D 331111 CDS YP_001462525.1 157158011 5586269 1425606..1426157 1 NC_009801.1 identified by match to protein family HMM PF06254; hypothetical protein 1426157 5586269 EcE24377A_1423 Escherichia coli E24377A hypothetical protein YP_001462525.1 1425606 D 331111 CDS YP_001462526.1 157155135 5589176 1426129..1427169 1 NC_009801.1 identified by similarity to GB:AAW62196.1; hypothetical protein 1427169 5589176 EcE24377A_1424 Escherichia coli E24377A hypothetical protein YP_001462526.1 1426129 D 331111 CDS YP_001462527.1 157155681 5589066 1426958..1427623 1 NC_009801.1 hypothetical protein 1427623 5589066 EcE24377A_1425 Escherichia coli E24377A hypothetical protein YP_001462527.1 1426958 D 331111 CDS YP_001462528.1 157156500 5590705 1427653..1428048 1 NC_009801.1 identified by similarity to GB:BAB35696.1; match to protein family HMM PF06163; hypothetical protein 1428048 5590705 EcE24377A_1426 Escherichia coli E24377A hypothetical protein YP_001462528.1 1427653 D 331111 CDS YP_001462529.1 157157030 5588380 1428051..1428341 1 NC_009801.1 hypothetical protein 1428341 5588380 EcE24377A_1427 Escherichia coli E24377A hypothetical protein YP_001462529.1 1428051 D 331111 CDS YP_001462530.1 157157748 5586325 1428722..1428934 1 NC_009801.1 identified by similarity to GB:BAB35372.1; hypothetical protein 1428934 5586325 EcE24377A_1429 Escherichia coli E24377A hypothetical protein YP_001462530.1 1428722 D 331111 CDS YP_001462531.1 157158566 5588175 complement(1429524..1430456) 1 NC_009801.1 identified by similarity to GB:CAD05601.1; hypothetical protein 1430456 5588175 EcE24377A_1430 Escherichia coli E24377A hypothetical protein YP_001462531.1 1429524 R 331111 CDS YP_001462532.1 157157536 5590737 1431077..1431193 1 NC_009801.1 identified by glimmer; hypothetical protein 1431193 5590737 EcE24377A_1431 Escherichia coli E24377A hypothetical protein YP_001462532.1 1431077 D 331111 CDS YP_001462533.1 157155997 5588970 1431258..1431506 1 NC_009801.1 identified by similarity to GB:ABB61576.1; hypothetical protein 1431506 5588970 EcE24377A_1433 Escherichia coli E24377A hypothetical protein YP_001462533.1 1431258 D 331111 CDS YP_001462534.1 157155483 5588902 1431853..1432902 1 NC_009801.1 identified by similarity to GB:AAN79892.1; match to protein family HMM PF06914; hypothetical protein 1432902 5588902 EcE24377A_1434 Escherichia coli E24377A hypothetical protein YP_001462534.1 1431853 D 331111 CDS YP_001462535.1 157155088 5586831 1432915..1433274 1 NC_009801.1 identified by similarity to SP:Q9MCN8; match to protein family HMM PF05866; crossover junction endodeoxyribonuclease RusA-like protein 1433274 5586831 EcE24377A_1435 Escherichia coli E24377A crossover junction endodeoxyribonuclease RusA-like protein YP_001462535.1 1432915 D 331111 CDS YP_001462536.1 157158789 5586652 1433271..1433960 1 NC_009801.1 identified by match to protein family HMM PF06323; phage antitermination protein Q 1433960 5586652 EcE24377A_1436 Escherichia coli E24377A phage antitermination protein Q YP_001462536.1 1433271 D 331111 CDS YP_001462537.1 157158263 5587974 1434030..1434869 1 NC_009801.1 identified by match to protein family HMM PF00069; protein kinase domain-containing protein 1434869 5587974 EcE24377A_1437 Escherichia coli E24377A protein kinase domain-containing protein YP_001462537.1 1434030 D 331111 CDS YP_001462538.1 157156540 5587778 1434866..1435609 1 NC_009801.1 identified by glimmer; hypothetical protein 1435609 5587778 EcE24377A_1438 Escherichia coli E24377A hypothetical protein YP_001462538.1 1434866 D 331111 CDS YP_001462539.1 157156014 5589946 1435742..1436026 1 NC_009801.1 identified by similarity to GB:CAE15837.1; hypothetical protein 1436026 5589946 EcE24377A_1439 Escherichia coli E24377A hypothetical protein YP_001462539.1 1435742 D 331111 CDS YP_001462540.1 157156068 5586485 1436177..1437223 1 NC_009801.1 identified by match to protein family HMM PF01555; DNA methylase 1437223 5586485 EcE24377A_1440 Escherichia coli E24377A DNA methylase YP_001462540.1 1436177 D 331111 CDS YP_001462541.1 157155526 5586562 1438724..1439074 1 NC_009801.1 identified by similarity to GB:CAB93764.1; hypothetical protein 1439074 5586562 EcE24377A_1443 Escherichia coli E24377A hypothetical protein YP_001462541.1 1438724 D 331111 CDS YP_001462542.1 157157395 5590759 1439071..1439322 1 NC_009801.1 identified by glimmer; hypothetical protein 1439322 5590759 EcE24377A_1444 Escherichia coli E24377A hypothetical protein YP_001462542.1 1439071 D 331111 CDS YP_001462543.1 157159232 5589408 1439331..1440413 1 NC_009801.1 identified by match to protein family HMM PF05136; lambda family phage portal protein 1440413 5589408 EcE24377A_1445 Escherichia coli E24377A lambda family phage portal protein YP_001462543.1 1439331 D 331111 CDS YP_001462544.1 157155616 5586317 1440410..1440844 1 NC_009801.1 hypothetical protein 1440844 5586317 EcE24377A_1446 Escherichia coli E24377A hypothetical protein YP_001462544.1 1440410 D 331111 CDS YP_001462545.1 157155083 5586399 1440816..1441031 1 NC_009801.1 identified by glimmer; hypothetical protein 1441031 5586399 EcE24377A_1447 Escherichia coli E24377A hypothetical protein YP_001462545.1 1440816 D 331111 CDS YP_001462546.1 157156982 5588507 1441015..1441347 1 NC_009801.1 hypothetical protein 1441347 5588507 EcE24377A_1448 Escherichia coli E24377A hypothetical protein YP_001462546.1 1441015 D 331111 CDS YP_001462547.1 157156594 5589748 1441496..1441693 1 NC_009801.1 hypothetical protein 1441693 5589748 EcE24377A_1449 Escherichia coli E24377A hypothetical protein YP_001462547.1 1441496 D 331111 CDS YP_001462548.1 157157749 5589499 1441690..1444236 1 NC_009801.1 identified by glimmer; hypothetical protein 1444236 5589499 EcE24377A_1450 Escherichia coli E24377A hypothetical protein YP_001462548.1 1441690 D 331111 CDS YP_001462549.1 157157303 5588714 1444283..1445074 1 NC_009801.1 identified by glimmer; hypothetical protein 1445074 5588714 EcE24377A_1451 Escherichia coli E24377A hypothetical protein YP_001462549.1 1444283 D 331111 CDS YP_001462550.1 157159182 5590302 1445087..1445626 1 NC_009801.1 identified by match to protein family HMM PF02413; hypothetical protein 1445626 5590302 EcE24377A_1452 Escherichia coli E24377A hypothetical protein YP_001462550.1 1445087 D 331111 CDS YP_001462551.1 157158654 5586955 complement(1447274..1447834) 1 NC_009801.1 hypothetical protein 1447834 5586955 EcE24377A_1453 Escherichia coli E24377A hypothetical protein YP_001462551.1 1447274 R 331111 CDS YP_001462552.1 157157233 5589179 1448307..1448423 1 NC_009801.1 identified by match to protein family HMM TIGR03304; hypothetical protein 1448423 5589179 EcE24377A_1454 Escherichia coli E24377A hypothetical protein YP_001462552.1 1448307 D 331111 CDS YP_001462553.1 157157720 5588085 complement(1448483..1448989) 1 NC_009801.1 identified by match to protein family HMM PF05974; hypothetical protein 1448989 5588085 EcE24377A_1455 Escherichia coli E24377A hypothetical protein YP_001462553.1 1448483 R 331111 CDS YP_001462554.1 157156495 5589274 complement(1449035..1449535) 1 NC_009801.1 identified by match to protein family HMM PF05974; hypothetical protein 1449535 yciF 5589274 yciF Escherichia coli E24377A hypothetical protein YP_001462554.1 1449035 R 331111 CDS YP_001462555.1 157156995 5590569 complement(1449593..1449787) 1 NC_009801.1 identified by similarity to GB:AAX64977.1; hypothetical protein 1449787 5590569 EcE24377A_1457 Escherichia coli E24377A hypothetical protein YP_001462555.1 1449593 R 331111 CDS YP_001462556.1 157158483 5590481 complement(1449621..1449800) 1 NC_009801.1 identified by similarity to OMNI:NTL01EC01230; hypothetical protein 1449800 5590481 EcE24377A_1458 Escherichia coli E24377A hypothetical protein YP_001462556.1 1449621 R 331111 CDS YP_001462557.1 157155085 5586791 complement(1450181..1450987) 1 NC_009801.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1450987 trpA 5586791 trpA Escherichia coli E24377A tryptophan synthase subunit alpha YP_001462557.1 1450181 R 331111 CDS YP_001462558.1 157157226 5588370 complement(1450987..1452180) 1 NC_009801.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1452180 trpB 5588370 trpB Escherichia coli E24377A tryptophan synthase subunit beta YP_001462558.1 1450987 R 331111 CDS YP_001462559.1 157157701 5589778 complement(1452192..1453550) 1 NC_009801.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1453550 trpC 5589778 trpC Escherichia coli E24377A bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_001462559.1 1452192 R 331111 CDS YP_001462560.1 157157057 5586212 complement(1453554..1455149) 1 NC_009801.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 1455149 trpD 5586212 trpD Escherichia coli E24377A bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase YP_001462560.1 1453554 R 331111 CDS YP_001462561.1 157155349 5589445 1455072..1455170 1 NC_009801.1 identified by glimmer; hypothetical protein 1455170 5589445 EcE24377A_1464 Escherichia coli E24377A hypothetical protein YP_001462561.1 1455072 D 331111 CDS YP_001462562.1 157157578 5590594 complement(1455149..1456711) 1 NC_009801.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1456711 trpE 5590594 trpE Escherichia coli E24377A anthranilate synthase component I YP_001462562.1 1455149 R 331111 CDS YP_001462563.1 157154837 5587685 1457006..1457866 1 NC_009801.1 identified by match to protein family HMM PF02811; phosphoesterase 1457866 5587685 EcE24377A_1465 Escherichia coli E24377A phosphoesterase YP_001462563.1 1457006 D 331111 CDS YP_001462564.1 157155810 5586184 1457863..1458483 1 NC_009801.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; hypothetical protein 1458483 5586184 EcE24377A_1466 Escherichia coli E24377A hypothetical protein YP_001462564.1 1457863 D 331111 CDS YP_001462565.1 157154729 5586238 1458584..1459456 1 NC_009801.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1459456 rluB 5586238 rluB Escherichia coli E24377A 23S rRNA pseudouridylate synthase B YP_001462565.1 1458584 D 331111 CDS YP_001462566.1 157159251 5589391 complement(1459496..1460086) 1 NC_009801.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1460086 btuR 5589391 btuR Escherichia coli E24377A cob(I)yrinic acid a,c-diamide adenosyltransferase YP_001462566.1 1459496 R 331111 CDS YP_001462567.1 157158085 5589239 complement(1460083..1460841) 1 NC_009801.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659; short chain dehydrogenase 1460841 5589239 EcE24377A_1470 Escherichia coli E24377A short chain dehydrogenase YP_001462567.1 1460083 R 331111 CDS YP_001462568.1 157157433 5587058 1461061..1462110 1 NC_009801.1 SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1462110 sohB 5587058 sohB Escherichia coli E24377A periplasmic protease YP_001462568.1 1461061 D 331111 CDS YP_001462569.1 157156815 5590398 1462080..1462172 1 NC_009801.1 identified by glimmer; hypothetical protein 1462172 5590398 EcE24377A_1473 Escherichia coli E24377A hypothetical protein YP_001462569.1 1462080 D 331111 CDS YP_001462570.1 157154945 5586799 complement(1462146..1462397) 1 NC_009801.1 hypothetical protein 1462397 5586799 EcE24377A_1472 Escherichia coli E24377A hypothetical protein YP_001462570.1 1462146 R 331111 CDS YP_001462571.1 157159421 5588168 1462777..1465374 1 NC_009801.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1465374 topA 5588168 topA Escherichia coli E24377A DNA topoisomerase I YP_001462571.1 1462777 D 331111 CDS YP_001462572.1 157157588 5589929 1465584..1466558 1 NC_009801.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1466558 cysB 5589929 cysB Escherichia coli E24377A transcriptional regulator CysB YP_001462572.1 1465584 D 331111 CDS YP_001462573.1 157154844 5590876 1466877..1467017 1 NC_009801.1 hypothetical protein 1467017 5590876 EcE24377A_1476 Escherichia coli E24377A hypothetical protein YP_001462573.1 1466877 D 331111 CDS YP_001462574.1 157155351 5586252 1467008..1467187 1 NC_009801.1 hypothetical protein 1467187 5586252 EcE24377A_1477 Escherichia coli E24377A hypothetical protein YP_001462574.1 1467008 D 331111 CDS YP_001462575.1 157154783 5589997 1467560..1470235 1 NC_009801.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1470235 acnA 5589997 acnA Escherichia coli E24377A aconitate hydratase YP_001462575.1 1467560 D 331111 CDS YP_001462576.1 157155420 5588747 complement(1470299..1470889) 1 NC_009801.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1470889 ribA 5588747 ribA Escherichia coli E24377A GTP cyclohydrolase II YP_001462576.1 1470299 R 331111 CDS YP_001462577.1 157156121 5590463 1471059..1471823 1 NC_009801.1 identified by similarity to SP:P0A924; match to protein family HMM PF01569; phosphatidylglycerophosphatase B 1471823 pgpB 5590463 pgpB Escherichia coli E24377A phosphatidylglycerophosphatase B YP_001462577.1 1471059 D 331111 CDS YP_001462578.1 157156793 5587612 1471972..1472280 1 NC_009801.1 identified by match to protein family HMM PF06305; hypothetical protein 1472280 5587612 EcE24377A_1481 Escherichia coli E24377A hypothetical protein YP_001462578.1 1471972 D 331111 CDS YP_001462579.1 157157418 5588164 1472287..1473456 1 NC_009801.1 identified by match to protein family HMM PF07719; tetratricopeptide repeat protein 1473456 5588164 EcE24377A_1482 Escherichia coli E24377A tetratricopeptide repeat protein YP_001462579.1 1472287 D 331111 CDS YP_001462580.1 157158214 5590571 complement(1473490..1473633) 1 NC_009801.1 identified by glimmer; hypothetical protein 1473633 5590571 EcE24377A_1483 Escherichia coli E24377A hypothetical protein YP_001462580.1 1473490 R 331111 CDS YP_001462581.1 157158650 5588363 1473649..1474386 1 NC_009801.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1474386 pyrF 5588363 pyrF Escherichia coli E24377A orotidine 5'-phosphate decarboxylase YP_001462581.1 1473649 D 331111 CDS YP_001462582.1 157159191 5589369 1474386..1474712 1 NC_009801.1 involved in start site selection during the initiation of translation; translation initiation factor Sui1 1474712 5589369 EcE24377A_1485 Escherichia coli E24377A translation initiation factor Sui1 YP_001462582.1 1474386 D 331111 CDS YP_001462583.1 157156348 5589537 complement(1474838..1475056) 1 NC_009801.1 identified by similarity to SP:P0ADA7; lipoprotein 1475056 5589537 EcE24377A_1486 Escherichia coli E24377A lipoprotein YP_001462583.1 1474838 R 331111 CDS YP_001462584.1 157157058 5586393 complement(1475325..1476074) 1 NC_009801.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; DeoR family transcriptional regulator 1476074 5586393 EcE24377A_1487 Escherichia coli E24377A DeoR family transcriptional regulator YP_001462584.1 1475325 R 331111 CDS YP_001462585.1 157155148 5589446 complement(1476164..1476346) 1 NC_009801.1 hypothetical protein 1476346 5589446 EcE24377A_1488 Escherichia coli E24377A hypothetical protein YP_001462585.1 1476164 R 331111 CDS YP_001462586.1 157155383 5589676 complement(1476484..1478469) 1 NC_009801.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator 1478469 5589676 EcE24377A_1489 Escherichia coli E24377A RNase II stability modulator YP_001462586.1 1476484 R 331111 CDS YP_001462587.1 157158303 5589378 complement(1478573..1478680) 1 NC_009801.1 identified by glimmer; hypothetical protein 1478680 5589378 EcE24377A_1490 Escherichia coli E24377A hypothetical protein YP_001462587.1 1478573 R 331111 CDS YP_001462588.1 157159110 5589681 complement(1478704..1480638) 1 NC_009801.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 1480638 rnb 5589681 rnb Escherichia coli E24377A exoribonuclease II YP_001462588.1 1478704 R 331111 CDS YP_001462589.1 157157317 5587910 complement(1480706..1481911) 1 NC_009801.1 hypothetical protein 1481911 5587910 EcE24377A_1492 Escherichia coli E24377A hypothetical protein YP_001462589.1 1480706 R 331111 CDS YP_001462590.1 157158715 5586336 complement(1481862..1481969) 1 NC_009801.1 identified by glimmer; hypothetical protein 1481969 5586336 EcE24377A_1493 Escherichia coli E24377A hypothetical protein YP_001462590.1 1481862 R 331111 CDS YP_001462591.1 157155907 5589635 complement(1481978..1482766) 1 NC_009801.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 1482766 fabI 5589635 fabI Escherichia coli E24377A enoyl-ACP reductase YP_001462591.1 1481978 R 331111 CDS YP_001462592.1 157156330 5586605 1482781..1482879 1 NC_009801.1 identified by glimmer; hypothetical protein 1482879 5586605 EcE24377A_1495 Escherichia coli E24377A hypothetical protein YP_001462592.1 1482781 D 331111 CDS YP_001462593.1 157156848 5590820 complement(1483134..1483484) 1 NC_009801.1 identified by match to protein family HMM PF04480; hypothetical protein 1483484 5590820 EcE24377A_1496 Escherichia coli E24377A hypothetical protein YP_001462593.1 1483134 R 331111 CDS YP_001462594.1 157156325 5587794 complement(1483555..1484361) 1 NC_009801.1 identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein SapF 1484361 sapF 5587794 sapF Escherichia coli E24377A peptide ABC transporter ATP-binding protein SapF YP_001462594.1 1483555 R 331111 CDS YP_001462595.1 157156906 5588733 complement(1484363..1485355) 1 NC_009801.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; peptide ABC transporter ATP-binding protein SapD 1485355 sapD 5588733 sapD Escherichia coli E24377A peptide ABC transporter ATP-binding protein SapD YP_001462595.1 1484363 R 331111 CDS YP_001462596.1 157157948 5590252 complement(1485355..1486245) 1 NC_009801.1 identified by match to protein family HMM PF00528; peptide ABC transporter permease SapC 1486245 sapC 5590252 sapC Escherichia coli E24377A peptide ABC transporter permease SapC YP_001462596.1 1485355 R 331111 CDS YP_001462597.1 157158421 5590190 complement(1486232..1487197) 1 NC_009801.1 identified by match to protein family HMM PF00528; peptide ABC transporter permease SapB 1487197 sapB 5590190 sapB Escherichia coli E24377A peptide ABC transporter permease SapB YP_001462597.1 1486232 R 331111 CDS YP_001462598.1 157158938 5590636 complement(1487194..1488837) 1 NC_009801.1 identified by match to protein family HMM PF00496; peptide ABC transporter periplasmic peptide-binding protein 1488837 sapA 5590636 sapA Escherichia coli E24377A peptide ABC transporter periplasmic peptide-binding protein YP_001462598.1 1487194 R 331111 CDS YP_001462599.1 157155756 5586814 1489043..1489168 1 NC_009801.1 identified by glimmer; hypothetical protein 1489168 5586814 EcE24377A_1503 Escherichia coli E24377A hypothetical protein YP_001462599.1 1489043 D 331111 CDS YP_001462600.1 157155302 5589689 complement(1489150..1489395) 1 NC_009801.1 hypothetical protein 1489395 5589689 EcE24377A_1502 Escherichia coli E24377A hypothetical protein YP_001462600.1 1489150 R 331111 CDS YP_001462601.1 157157343 5589954 complement(1489411..1489521) 1 NC_009801.1 identified by glimmer; hypothetical protein 1489521 5589954 EcE24377A_1504 Escherichia coli E24377A hypothetical protein YP_001462601.1 1489411 R 331111 CDS YP_001462602.1 157155487 5589866 complement(1489529..1490914) 1 NC_009801.1 identified by match to protein family HMM PF00324; amino acid permease 1490914 5589866 EcE24377A_1505 Escherichia coli E24377A amino acid permease YP_001462602.1 1489529 R 331111 CDS YP_001462603.1 157154986 5588490 complement(1491217..1492635) 1 NC_009801.1 identified by similarity to SP:P78061; match to protein family HMM PF00120; glutamate--putrescine ligase 1492635 puuA 5588490 puuA Escherichia coli E24377A glutamate--putrescine ligase YP_001462603.1 1491217 R 331111 CDS YP_001462604.1 157159227 5586989 complement(1492823..1492957) 1 NC_009801.1 identified by glimmer; hypothetical protein 1492957 5586989 EcE24377A_1507 Escherichia coli E24377A hypothetical protein YP_001462604.1 1492823 R 331111 CDS YP_001462605.1 157158718 5589767 1492847..1493611 1 NC_009801.1 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate; gamma-glutamyl-gamma-aminobutyrate hydrolase 1493611 puuD 5589767 puuD Escherichia coli E24377A gamma-glutamyl-gamma-aminobutyrate hydrolase YP_001462605.1 1492847 D 331111 CDS YP_001462606.1 157158238 5589306 1493638..1494195 1 NC_009801.1 regulates genes involved in putrescine degradation; DNA-binding transcriptional repressor PuuR 1494195 puuR 5589306 puuR Escherichia coli E24377A DNA-binding transcriptional repressor PuuR YP_001462606.1 1493638 D 331111 CDS YP_001462607.1 157157669 5586521 1494345..1495832 1 NC_009801.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 1495832 puuC 5586521 puuC Escherichia coli E24377A gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase YP_001462607.1 1494345 D 331111 CDS YP_001462608.1 157157224 5589210 1495834..1497114 1 NC_009801.1 identified by similarity to SP:P37906; match to protein family HMM PF01266; gamma-glutamylputrescine oxidoreductase 1497114 puuB 5589210 puuB Escherichia coli E24377A gamma-glutamylputrescine oxidoreductase YP_001462608.1 1495834 D 331111 CDS YP_001462609.1 157156698 5586616 1497152..1498417 1 NC_009801.1 putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 1498417 gabT1 5586616 gabT1 Escherichia coli E24377A 4-aminobutyrate aminotransferase YP_001462609.1 1497152 D 331111 CDS YP_001462610.1 157154719 5586982 complement(1498537..1499514) 1 NC_009801.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator 1499514 pspF 5586982 pspF Escherichia coli E24377A phage shock protein operon transcriptional activator YP_001462610.1 1498537 R 331111 CDS YP_001462611.1 157158696 5586007 1499681..1500349 1 NC_009801.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1500349 pspA 5586007 pspA Escherichia coli E24377A phage shock protein PspA YP_001462611.1 1499681 D 331111 CDS YP_001462612.1 157157209 5589020 1500403..1500627 1 NC_009801.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1500627 pspB 5589020 pspB Escherichia coli E24377A phage shock protein B YP_001462612.1 1500403 D 331111 CDS YP_001462613.1 157157559 5586190 1500627..1500986 1 NC_009801.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1500986 pspC 5586190 pspC Escherichia coli E24377A DNA-binding transcriptional activator PspC YP_001462613.1 1500627 D 331111 CDS YP_001462614.1 157157984 5589384 1500995..1501216 1 NC_009801.1 identified by match to protein family HMM TIGR02979; peripheral inner membrane phage-shock protein 1501216 pspD 5589384 pspD Escherichia coli E24377A peripheral inner membrane phage-shock protein YP_001462614.1 1500995 D 331111 CDS YP_001462615.1 157157175 5588195 1501291..1501605 1 NC_009801.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1501605 pspE 5588195 pspE Escherichia coli E24377A thiosulfate:cyanide sulfurtransferase YP_001462615.1 1501291 D 331111 CDS YP_001462616.1 157156941 5588142 1501818..1503497 1 NC_009801.1 identified by match to protein family HMM PF00128; alpha amylase 1503497 5588142 EcE24377A_1519 Escherichia coli E24377A alpha amylase YP_001462616.1 1501818 D 331111 CDS YP_001462617.1 157156291 5588081 1503511..1504803 1 NC_009801.1 identified by match to protein family HMM PF01547; sugar ABC transporter periplasmic sugar-binding protein 1504803 5588081 EcE24377A_1520 Escherichia coli E24377A sugar ABC transporter periplasmic sugar-binding protein YP_001462617.1 1503511 D 331111 CDS YP_001462618.1 157158779 5590212 1504824..1505705 1 NC_009801.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 1505705 5590212 EcE24377A_1521 Escherichia coli E24377A sugar ABC transporter permease YP_001462618.1 1504824 D 331111 CDS YP_001462619.1 157155749 5587006 1505692..1506534 1 NC_009801.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 1506534 5587006 EcE24377A_1522 Escherichia coli E24377A sugar ABC transporter permease YP_001462619.1 1505692 D 331111 CDS YP_001462620.1 157158912 5589235 1506565..1507617 1 NC_009801.1 identified by match to protein family HMM PF00107; zinc-binding dehydrogenase oxidoreductase 1507617 5589235 EcE24377A_1523 Escherichia coli E24377A zinc-binding dehydrogenase oxidoreductase YP_001462620.1 1506565 D 331111 CDS YP_001462621.1 157156136 5590732 1507636..1508424 1 NC_009801.1 identified by match to protein family HMM PF01261; AP endonuclease 1508424 5590732 EcE24377A_1524 Escherichia coli E24377A AP endonuclease YP_001462621.1 1507636 D 331111 CDS YP_001462622.1 157156714 5587765 1508434..1509489 1 NC_009801.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; gfo/idh/mocA family protein 1509489 5587765 EcE24377A_1525 Escherichia coli E24377A gfo/idh/mocA family protein YP_001462622.1 1508434 D 331111 CDS YP_001462623.1 157155852 5586196 1509486..1511753 1 NC_009801.1 identified by match to protein family HMM PF03632; match to protein family HMM PF03633; match to protein family HMM PF03636; glycosyl hydrolase 1511753 5586196 EcE24377A_1527 Escherichia coli E24377A glycosyl hydrolase YP_001462623.1 1509486 D 331111 CDS YP_001462624.1 157156103 5587050 complement(1511640..1511738) 1 NC_009801.1 identified by glimmer; hypothetical protein 1511738 5587050 EcE24377A_1526 Escherichia coli E24377A hypothetical protein YP_001462624.1 1511640 R 331111 CDS YP_001462625.1 157154852 5586534 1511750..1512409 1 NC_009801.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; match to protein family HMM TIGR01990; match to protein family HMM TIGR02009; beta-phosphoglucomutase 1512409 pgmB 5586534 pgmB Escherichia coli E24377A beta-phosphoglucomutase YP_001462625.1 1511750 D 331111 CDS YP_001462626.1 157159284 5589068 1512423..1513505 1 NC_009801.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402; sugar ABC transporter ATP-binding protein 1513505 5589068 EcE24377A_1529 Escherichia coli E24377A sugar ABC transporter ATP-binding protein YP_001462626.1 1512423 D 331111 CDS YP_001462627.1 157158763 5589950 1513550..1514455 1 NC_009801.1 identified by match to protein family HMM TIGR03304; outer membrane protein G 1514455 ompG 5589950 ompG Escherichia coli E24377A outer membrane protein G YP_001462627.1 1513550 D 331111 CDS YP_001462628.1 157156207 5589128 complement(1514566..1515564) 1 NC_009801.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; LacI family transcriptional regulator 1515564 5589128 EcE24377A_1531 Escherichia coli E24377A LacI family transcriptional regulator YP_001462628.1 1514566 R 331111 CDS YP_001462629.1 157157464 5587780 1515719..1517116 1 NC_009801.1 identified by match to protein family HMM PF04317; hypothetical protein 1517116 5587780 EcE24377A_1532 Escherichia coli E24377A hypothetical protein YP_001462629.1 1515719 D 331111 CDS YP_001462630.1 157158818 5587447 1517113..1518174 1 NC_009801.1 identified by similarity to GB:ABB66349.1; match to protein family HMM PF05128; match to protein family HMM TIGR01620; hypothetical protein 1518174 5587447 EcE24377A_1533 Escherichia coli E24377A hypothetical protein YP_001462630.1 1517113 D 331111 CDS YP_001462631.1 157159433 5590261 1518322..1519863 1 NC_009801.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1519863 tyrR 5590261 tyrR Escherichia coli E24377A DNA-binding transcriptional regulator TyrR YP_001462631.1 1518322 D 331111 CDS YP_001462632.1 157155990 5587650 complement(1519907..1520413) 1 NC_009801.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1520413 tpx 5587650 tpx Escherichia coli E24377A thiol peroxidase YP_001462632.1 1519907 R 331111 CDS YP_001462633.1 157157714 5589968 1520532..1521497 1 NC_009801.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746; mandelate racemase/muconate lactonizing enzyme family protein 1521497 5589968 EcE24377A_1537 Escherichia coli E24377A mandelate racemase/muconate lactonizing enzyme family protein YP_001462633.1 1520532 D 331111 CDS YP_001462634.1 157155460 5589145 complement(1521472..1522200) 1 NC_009801.1 identified by match to protein family HMM PF00246; murein peptide amidase A 1522200 5589145 EcE24377A_1536 Escherichia coli E24377A murein peptide amidase A YP_001462634.1 1521472 R 331111 CDS YP_001462635.1 157157334 5586434 complement(1522510..1523148) 1 NC_009801.1 identified by match to protein family HMM PF05368; NmrA family protein 1523148 5586434 EcE24377A_1538 Escherichia coli E24377A NmrA family protein YP_001462635.1 1522510 R 331111 CDS YP_001462636.1 157159082 5589668 complement(1523166..1524098) 1 NC_009801.1 identified by similarity to GB:BAC59941.1; hypothetical protein 1524098 5589668 EcE24377A_1539 Escherichia coli E24377A hypothetical protein YP_001462636.1 1523166 R 331111 CDS YP_001462637.1 157158111 5587990 complement(1524098..1525018) 1 NC_009801.1 hypothetical protein 1525018 5587990 EcE24377A_1540 Escherichia coli E24377A hypothetical protein YP_001462637.1 1524098 R 331111 CDS YP_001462638.1 157155739 5589132 1525156..1526055 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1526055 5589132 EcE24377A_1541 Escherichia coli E24377A LysR family transcriptional regulator YP_001462638.1 1525156 D 331111 CDS YP_001462639.1 157155059 5589706 1526392..1528005 1 NC_009801.1 identified by match to protein family HMM PF00496; periplasmic murein peptide-binding protein 1528005 mppA 5589706 mppA Escherichia coli E24377A periplasmic murein peptide-binding protein YP_001462639.1 1526392 D 331111 CDS YP_001462640.1 157157019 5586597 complement(1528056..1529087) 1 NC_009801.1 identified by match to protein family HMM PF00924; small conductance mechanosensitive ion channel (MscS) family protein 1529087 5586597 EcE24377A_1543 Escherichia coli E24377A small conductance mechanosensitive ion channel (MscS) family protein YP_001462640.1 1528056 R 331111 CDS YP_001462641.1 157156028 5588383 complement(1529638..1530588) 1 NC_009801.1 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1530588 uspE 5588383 uspE Escherichia coli E24377A universal stress protein UspE YP_001462641.1 1529638 R 331111 CDS YP_001462642.1 157157974 5587256 complement(1530740..1531492) 1 NC_009801.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1531492 fnr 5587256 fnr Escherichia coli E24377A fumarate/nitrate reduction transcriptional regulator YP_001462642.1 1530740 R 331111 CDS YP_001462643.1 157158689 5586394 complement(1532209..1533735) 1 NC_009801.1 identified by similarity to SP:P46133; match to protein family HMM PF03806; match to protein family HMM TIGR00819; aminobenzoyl-glutamate transporter 1533735 abgT 5586394 abgT Escherichia coli E24377A aminobenzoyl-glutamate transporter YP_001462643.1 1532209 R 331111 CDS YP_001462644.1 157155757 5590415 complement(1533772..1535217) 1 NC_009801.1 identified by similarity to SP:P76052; match to protein family HMM PF01546; match to protein family HMM TIGR01891; aminobenzoyl-glutamate utilization protein B 1535217 abgB 5590415 abgB Escherichia coli E24377A aminobenzoyl-glutamate utilization protein B YP_001462644.1 1533772 R 331111 CDS YP_001462645.1 157157633 5588307 complement(1535217..1536527) 1 NC_009801.1 identified by similarity to SP:P77357; match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; aminobenzoyl-glutamate utilization protein A 1536527 abgA 5588307 abgA Escherichia coli E24377A aminobenzoyl-glutamate utilization protein A YP_001462645.1 1535217 R 331111 CDS YP_001462646.1 157159041 5588634 complement(1536502..1536606) 1 NC_009801.1 identified by glimmer; hypothetical protein 1536606 5588634 EcE24377A_1551 Escherichia coli E24377A hypothetical protein YP_001462646.1 1536502 R 331111 CDS YP_001462647.1 157155060 5589691 complement(1536603..1536704) 1 NC_009801.1 identified by glimmer; hypothetical protein 1536704 5589691 EcE24377A_1552 Escherichia coli E24377A hypothetical protein YP_001462647.1 1536603 R 331111 CDS YP_001462648.1 157159170 5586598 1536703..1537611 1 NC_009801.1 identified by similarity to SP:P77744; match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator 1537611 5586598 EcE24377A_1553 Escherichia coli E24377A DNA-binding transcriptional regulator YP_001462648.1 1536703 D 331111 CDS YP_001462649.1 157157039 5587467 1537941..1538504 1 NC_009801.1 identified by match to protein family HMM PF01713; Smr domain-containing protein 1538504 5587467 EcE24377A_1554 Escherichia coli E24377A Smr domain-containing protein YP_001462649.1 1537941 D 331111 CDS YP_001462650.1 157155005 5589041 complement(1538525..1539817) 1 NC_009801.1 identified by match to protein family HMM PF00990; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; sensory box-containing diguanylate cyclase 1539817 5589041 EcE24377A_1555 Escherichia coli E24377A sensory box-containing diguanylate cyclase YP_001462650.1 1538525 R 331111 CDS YP_001462651.1 157157762 5587546 1540012..1540995 1 NC_009801.1 identified by match to protein family HMM PF01544; zinc transporter 1540995 zntB 5587546 zntB Escherichia coli E24377A zinc transporter YP_001462651.1 1540012 D 331111 CDS YP_001462652.1 157156397 5589089 1541473..1542846 1 NC_009801.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1542846 dbpA 5589089 dbpA Escherichia coli E24377A ATP-dependent RNA helicase DbpA YP_001462652.1 1541473 D 331111 CDS YP_001462653.1 157159153 5589496 complement(1542975..1543910) 1 NC_009801.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1543910 5589496 EcE24377A_1558 Escherichia coli E24377A C32 tRNA thiolase YP_001462653.1 1542975 R 331111 CDS YP_001462654.1 157157161 5588251 complement(1544086..1544520) 1 NC_009801.1 identified by similarity to SP:P37903; match to protein family HMM PF00582; universal stress protein F 1544520 uspF 5588251 uspF Escherichia coli E24377A universal stress protein F YP_001462654.1 1544086 R 331111 CDS YP_001462655.1 157155044 5588612 complement(1544661..1545794) 1 NC_009801.1 identified by similarity to SP:P77747; match to protein family HMM PF00267; outer membrane protein N 1545794 ompN 5588612 ompN Escherichia coli E24377A outer membrane protein N YP_001462655.1 1544661 R 331111 CDS YP_001462656.1 157155711 5589265 complement(1546161..1549685) 1 NC_009801.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176; pyruvate-flavodoxin oxidoreductase 1549685 ydbK 5589265 ydbK Escherichia coli E24377A pyruvate-flavodoxin oxidoreductase YP_001462656.1 1546161 R 331111 CDS YP_001462657.1 157156497 5588452 complement(1549695..1549826) 1 NC_009801.1 identified by glimmer; hypothetical protein 1549826 5588452 EcE24377A_1562 Escherichia coli E24377A hypothetical protein YP_001462657.1 1549695 R 331111 CDS YP_001462658.1 157157843 5587238 1549959..1550225 1 NC_009801.1 lipoprotein 1550225 5587238 EcE24377A_1564 Escherichia coli E24377A lipoprotein YP_001462658.1 1549959 D 331111 CDS YP_001462659.1 157155294 5587300 complement(1550222..1550644) 1 NC_009801.1 identified by match to protein family HMM PF03724; heat-inducible protein 1550644 hslJ 5587300 hslJ Escherichia coli E24377A heat-inducible protein YP_001462659.1 1550222 R 331111 CDS YP_001462660.1 157157078 5589982 complement(1550755..1551744) 1 NC_009801.1 identified by similarity to SP:P52643; match to protein family HMM PF00389; match to protein family HMM PF02826; D-lactate dehydrogenase 1551744 idhA 5589982 idhA Escherichia coli E24377A D-lactate dehydrogenase YP_001462660.1 1550755 R 331111 CDS YP_001462661.1 157158670 5590767 1551952..1554591 1 NC_009801.1 identified by similarity to SP:P52645; hypothetical protein 1554591 5590767 EcE24377A_1566 Escherichia coli E24377A hypothetical protein YP_001462661.1 1551952 D 331111 CDS YP_001462662.1 157155784 5590832 1554588..1554773 1 NC_009801.1 lipoprotein 1554773 5590832 EcE24377A_1567 Escherichia coli E24377A lipoprotein YP_001462662.1 1554588 D 331111 CDS YP_001462663.1 157158582 5587694 1554781..1555107 1 NC_009801.1 identified by similarity to GB:AAN80294.1; match to protein family HMM PF07027; hypothetical protein 1555107 5587694 EcE24377A_1568 Escherichia coli E24377A hypothetical protein YP_001462663.1 1554781 D 331111 CDS YP_001462664.1 157159310 5588275 complement(1555279..1556184) 1 NC_009801.1 activator of genes involved in phenylacetic acid catabolism; DNA-binding transcriptional activator FeaR 1556184 feaR 5588275 feaR Escherichia coli E24377A DNA-binding transcriptional activator FeaR YP_001462664.1 1555279 R 331111 CDS YP_001462665.1 157154879 5588851 1556420..1557919 1 NC_009801.1 identified by similarity to SP:P80668; match to protein family HMM PF00171; phenylacetaldehyde dehydrogenase 1557919 feaB 5588851 feaB Escherichia coli E24377A phenylacetaldehyde dehydrogenase YP_001462665.1 1556420 D 331111 CDS YP_001462666.1 157155545 5588329 complement(1557977..1560250) 1 NC_009801.1 catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine; tyramine oxidase 1560250 tynA 5588329 tynA Escherichia coli E24377A tyramine oxidase YP_001462666.1 1557977 R 331111 CDS YP_001462667.1 157158054 5586167 complement(1560498..1562543) 1 NC_009801.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase 1562543 paaN 5586167 paaN Escherichia coli E24377A bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase YP_001462667.1 1560498 R 331111 CDS YP_001462668.1 157155021 5586158 1562828..1563757 1 NC_009801.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; phenylacetate-CoA oxygenase subunit PaaA 1563757 paaA 5586158 paaA Escherichia coli E24377A phenylacetate-CoA oxygenase subunit PaaA YP_001462668.1 1562828 D 331111 CDS YP_001462669.1 157155727 5587131 1563769..1564056 1 NC_009801.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; phenylacetate-CoA oxygenase subunit PaaB 1564056 paaB 5587131 paaB Escherichia coli E24377A phenylacetate-CoA oxygenase subunit PaaB YP_001462669.1 1563769 D 331111 CDS YP_001462670.1 157158765 5587161 1564065..1564811 1 NC_009801.1 identified by match to protein family HMM PF05138; match to protein family HMM TIGR02158; phenylacetate-CoA oxygenase subunit PaaI 1564811 paaI 5587161 paaI Escherichia coli E24377A phenylacetate-CoA oxygenase subunit PaaI YP_001462670.1 1564065 D 331111 CDS YP_001462671.1 157159372 5589130 1564826..1565323 1 NC_009801.1 identified by match to protein family HMM PF01883; match to protein family HMM TIGR02159; phenylacetate-CoA oxygenase subunit PaaJ 1565323 paaJ 5589130 paaJ Escherichia coli E24377A phenylacetate-CoA oxygenase subunit PaaJ YP_001462671.1 1564826 D 331111 CDS YP_001462672.1 157157270 5589064 1565331..1566401 1 NC_009801.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM TIGR02160; phenylacetate-CoA oxygenase/reductase subunit PaaK 1566401 paaK 5589064 paaK Escherichia coli E24377A phenylacetate-CoA oxygenase/reductase subunit PaaK YP_001462672.1 1565331 D 331111 CDS YP_001462673.1 157157972 5590518 1566398..1567165 1 NC_009801.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase 1567165 5590518 EcE24377A_1578 Escherichia coli E24377A enoyl-CoA hydratase YP_001462673.1 1566398 D 331111 CDS YP_001462674.1 157155970 5586488 1567165..1567953 1 NC_009801.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1567953 paaB 5586488 paaB Escherichia coli E24377A enoyl-CoA hydratase YP_001462674.1 1567165 D 331111 CDS YP_001462675.1 157156253 5587504 1567955..1569382 1 NC_009801.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase 1569382 paaC 5587504 paaC Escherichia coli E24377A 3-hydroxyacyl-CoA dehydrogenase YP_001462675.1 1567955 D 331111 CDS YP_001462676.1 157154918 5590222 1569372..1569794 1 NC_009801.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; match to protein family HMM TIGR02286; phenylacetic acid degradation protein PaaD 1569794 paaD 5590222 paaD Escherichia coli E24377A phenylacetic acid degradation protein PaaD YP_001462676.1 1569372 D 331111 CDS YP_001462677.1 157155298 5590318 1569794..1570999 1 NC_009801.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase 1570999 pcaF 5590318 pcaF Escherichia coli E24377A beta-ketoadipyl CoA thiolase YP_001462677.1 1569794 D 331111 CDS YP_001462678.1 157157608 5586880 1571026..1572339 1 NC_009801.1 identified by match to protein family HMM TIGR02155; phenylacetate-CoA ligase 1572339 paaF 5586880 paaF Escherichia coli E24377A phenylacetate-CoA ligase YP_001462678.1 1571026 D 331111 CDS YP_001462679.1 157155909 5588349 complement(1572286..1572408) 1 NC_009801.1 identified by glimmer; hypothetical protein 1572408 5588349 EcE24377A_1583 Escherichia coli E24377A hypothetical protein YP_001462679.1 1572286 R 331111 CDS YP_001462680.1 157159302 5586607 1572440..1573390 1 NC_009801.1 identified by similarity to SP:P76086; match to protein family HMM PF07848; match to protein family HMM PF08223; match to protein family HMM TIGR02277; phenylacetic acid degradation operon negative regulatory protein PaaX 1573390 paaX 5586607 paaX Escherichia coli E24377A phenylacetic acid degradation operon negative regulatory protein PaaX YP_001462680.1 1572440 D 331111 CDS YP_001462681.1 157156795 5585960 1573372..1573962 1 NC_009801.1 identified by match to protein family HMM PF00132; match to protein family HMM TIGR02287; phenylacetic acid degradation protein PaaY 1573962 paaY 5585960 paaY Escherichia coli E24377A phenylacetic acid degradation protein PaaY YP_001462681.1 1573372 D 331111 CDS YP_001462682.1 157157067 5588310 1574194..1575054 1 NC_009801.1 identified by match to protein family HMM PF00248; oxidoreductase 1575054 5588310 EcE24377A_1587 Escherichia coli E24377A oxidoreductase YP_001462682.1 1574194 D 331111 CDS YP_001462683.1 157159197 5587430 1577595..1578200 1 NC_009801.1 identified by match to protein family HMM PF01066; CDP-alcohol phosphatidyltransferase 1578200 5587430 EcE24377A_1589 Escherichia coli E24377A CDP-alcohol phosphatidyltransferase YP_001462683.1 1577595 D 331111 CDS YP_001462684.1 157158657 5589432 1578200..1579096 1 NC_009801.1 identified by match to protein family HMM PF01148; phosphatidate cytidylyltransferase 1579096 cdsA2 5589432 cdsA2 Escherichia coli E24377A phosphatidate cytidylyltransferase YP_001462684.1 1578200 D 331111 CDS YP_001462685.1 157154972 5586451 1579112..1580869 1 NC_009801.1 hypothetical protein 1580869 5586451 EcE24377A_1591 Escherichia coli E24377A hypothetical protein YP_001462685.1 1579112 D 331111 CDS YP_001462686.1 157158380 5589116 1580883..1582175 1 NC_009801.1 identified by match to protein family HMM PF00782; match to protein family HMM PF01569; PAP2 family protein 1582175 5589116 EcE24377A_1592 Escherichia coli E24377A PAP2 family protein YP_001462686.1 1580883 D 331111 CDS YP_001462687.1 157157876 5589915 complement(1582226..1582831) 1 NC_009801.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 1582831 azoR 5589915 azoR Escherichia coli E24377A azoreductase YP_001462687.1 1582226 R 331111 CDS YP_001462688.1 157157344 5589871 1583032..1586934 1 NC_009801.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1586934 hrpA 5589871 hrpA Escherichia coli E24377A ATP-dependent RNA helicase HrpA YP_001462688.1 1583032 D 331111 CDS YP_001462689.1 157155538 5589867 1587206..1588006 1 NC_009801.1 identified by match to protein family HMM PF02698; hypothetical protein 1588006 5589867 EcE24377A_1595 Escherichia coli E24377A hypothetical protein YP_001462689.1 1587206 D 331111 CDS YP_001462690.1 157154889 5587726 1588203..1589642 1 NC_009801.1 NAD-linked; aldehyde dehydrogenase 1589642 aldA 5587726 aldA Escherichia coli E24377A aldehyde dehydrogenase YP_001462690.1 1588203 D 331111 CDS YP_001462691.1 157159393 5589755 complement(1589684..1590685) 1 NC_009801.1 identified by similarity to SP:P33898; match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 1590685 gapC 5589755 gapC Escherichia coli E24377A glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) YP_001462691.1 1589684 R 331111 CDS YP_001462692.1 157158613 5590454 1590838..1591404 1 NC_009801.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1591404 5590454 EcE24377A_1598 Escherichia coli E24377A cytochrome b561 YP_001462692.1 1590838 D 331111 CDS YP_001462693.1 157157191 5589071 1591649..1591822 1 NC_009801.1 hypothetical protein 1591822 5589071 EcE24377A_1599 Escherichia coli E24377A hypothetical protein YP_001462693.1 1591649 D 331111 CDS YP_001462694.1 157157689 5587324 1592442..1594082 1 NC_009801.1 identified by similarity to SP:P05704; match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203; methyl-accepting chemotaxis protein III 1594082 5587324 EcE24377A_1600 Escherichia coli E24377A methyl-accepting chemotaxis protein III YP_001462694.1 1592442 D 331111 CDS YP_001462695.1 157156163 5587181 complement(1594120..1595043) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1595043 5587181 EcE24377A_1601 Escherichia coli E24377A LysR family transcriptional regulator YP_001462695.1 1594120 R 331111 CDS YP_001462696.1 157159167 5589939 1595260..1596603 1 NC_009801.1 identified by similarity to SP:P15747; match to protein family HMM PF07063; hypothetical protein 1596603 5589939 EcE24377A_1602 Escherichia coli E24377A hypothetical protein YP_001462696.1 1595260 D 331111 CDS YP_001462697.1 157157100 5587242 1596828..1598483 1 NC_009801.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1598483 mdoD 5587242 mdoD Escherichia coli E24377A glucan biosynthesis protein D YP_001462697.1 1596828 D 331111 CDS YP_001462698.1 157155197 5586376 1598623..1598847 1 NC_009801.1 identified by similarity to GB:AAN80313.1; match to protein family HMM PF04325; hypothetical protein 1598847 5586376 EcE24377A_1604 Escherichia coli E24377A hypothetical protein YP_001462698.1 1598623 D 331111 CDS YP_001462699.1 157157349 5587956 1598910..1599446 1 NC_009801.1 identified by similarity to SP:P13857; match to protein family HMM PF00583; ribosomal-protein-L7/L12-serine acetyltransferase 1599446 rimL 5587956 rimL Escherichia coli E24377A ribosomal-protein-L7/L12-serine acetyltransferase YP_001462699.1 1598910 D 331111 CDS YP_001462700.1 157158099 5589252 complement(1599441..1600421) 1 NC_009801.1 identified by similarity to SP:P15644; hypothetical protein 1600421 5589252 EcE24377A_1605 Escherichia coli E24377A hypothetical protein YP_001462700.1 1599441 R 331111 CDS YP_001462701.1 157158433 5586211 1600545..1601537 1 NC_009801.1 identified by similarity to SP:P25396; match to protein family HMM PF03595; match to protein family HMM TIGR00816; potassium-tellurite ethidium and proflavin transporter 1601537 tehA 5586211 tehA Escherichia coli E24377A potassium-tellurite ethidium and proflavin transporter YP_001462701.1 1600545 D 331111 CDS YP_001462702.1 157158893 5588972 1601534..1602127 1 NC_009801.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1602127 tehB 5588972 tehB Escherichia coli E24377A tellurite resistance protein TehB YP_001462702.1 1601534 D 331111 CDS YP_001462703.1 157158439 5586947 1602431..1603099 1 NC_009801.1 lipoprotein 1603099 5586947 EcE24377A_1609 Escherichia coli E24377A lipoprotein YP_001462703.1 1602431 D 331111 CDS YP_001462704.1 157156473 5588017 1603631..1604839 1 NC_009801.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766; IS605 family transposase OrfB 1604839 5588017 EcE24377A_1611 Escherichia coli E24377A IS605 family transposase OrfB YP_001462704.1 1603631 D 331111 CDS YP_001462705.1 157156433 5589023 complement(1604879..1606147) 1 NC_009801.1 identified by match to protein family HMM PF00860; match to protein family HMM PF03594; match to protein family HMM TIGR00843; benzoate transporter 1606147 5589023 EcE24377A_1612 Escherichia coli E24377A benzoate transporter YP_001462705.1 1604879 R 331111 CDS YP_001462706.1 157157044 5589885 1606146..1606682 1 NC_009801.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883; DNA-binding protein 1606682 5589885 EcE24377A_1613 Escherichia coli E24377A DNA-binding protein YP_001462706.1 1606146 D 331111 CDS YP_001462707.1 157157126 5588801 1606713..1608716 1 NC_009801.1 identified by match to protein family HMM PF01136; U32 family peptidase 1608716 5588801 EcE24377A_1614 Escherichia coli E24377A U32 family peptidase YP_001462707.1 1606713 D 331111 CDS YP_001462708.1 157157905 5586122 complement(1608808..1609038) 1 NC_009801.1 hypothetical protein 1609038 5586122 EcE24377A_1615 Escherichia coli E24377A hypothetical protein YP_001462708.1 1608808 R 331111 CDS YP_001462709.1 157155102 5590119 complement(1609095..1609217) 1 NC_009801.1 identified by similarity to GB:AAN80324.1; hypothetical protein 1609217 5590119 EcE24377A_1616 Escherichia coli E24377A hypothetical protein YP_001462709.1 1609095 R 331111 CDS YP_001462710.1 157155653 5589459 1609461..1609898 1 NC_009801.1 identified by match to protein family HMM PF01381; match to protein family HMM PF03681; DNA-binding protein 1609898 5589459 EcE24377A_1617 Escherichia coli E24377A DNA-binding protein YP_001462710.1 1609461 D 331111 CDS YP_001462711.1 157156514 5588121 1609977..1611383 1 NC_009801.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392; GntR family transcriptional regulator 1611383 5588121 EcE24377A_1618 Escherichia coli E24377A GntR family transcriptional regulator YP_001462711.1 1609977 D 331111 CDS YP_001462712.1 157156409 5587215 1611628..1612773 1 NC_009801.1 identified by match to protein family HMM PF01547; ABC transporter periplasmic substrate-binding protein 1612773 ydcS 5587215 ydcS Escherichia coli E24377A ABC transporter periplasmic substrate-binding protein YP_001462712.1 1611628 D 331111 CDS YP_001462713.1 157155707 5586704 1612791..1613804 1 NC_009801.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402; ABC transporter ATP-binding protein 1613804 ydcT 5586704 ydcT Escherichia coli E24377A ABC transporter ATP-binding protein YP_001462713.1 1612791 D 331111 CDS YP_001462714.1 157155106 5589507 1613805..1614746 1 NC_009801.1 identified by match to protein family HMM PF00528; ABC transporter permease 1614746 ydcU 5589507 ydcU Escherichia coli E24377A ABC transporter permease YP_001462714.1 1613805 D 331111 CDS YP_001462715.1 157158611 5587995 1614736..1615530 1 NC_009801.1 identified by match to protein family HMM PF00528; ABC transporter permease 1615530 ydcV 5587995 ydcV Escherichia coli E24377A ABC transporter permease YP_001462715.1 1614736 D 331111 CDS YP_001462716.1 157157973 5586995 1615552..1616976 1 NC_009801.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1616976 ydcW 5586995 ydcW Escherichia coli E24377A gamma-aminobutyraldehyde dehydrogenase YP_001462716.1 1615552 D 331111 CDS YP_001462717.1 157157313 5586489 complement(1616973..1617089) 1 NC_009801.1 identified by glimmer; hypothetical protein 1617089 5586489 EcE24377A_1623 Escherichia coli E24377A hypothetical protein YP_001462717.1 1616973 R 331111 CDS YP_001462718.1 157156649 5590113 1617288..1617536 1 NC_009801.1 hypothetical protein 1617536 5590113 EcE24377A_1625 Escherichia coli E24377A hypothetical protein YP_001462718.1 1617288 D 331111 CDS YP_001462719.1 157155335 5590637 1617491..1617595 1 NC_009801.1 identified by glimmer; hypothetical protein 1617595 5590637 EcE24377A_1626 Escherichia coli E24377A hypothetical protein YP_001462719.1 1617491 D 331111 CDS YP_001462720.1 157154786 5589828 1617622..1617855 1 NC_009801.1 hypothetical protein 1617855 5589828 EcE24377A_1627 Escherichia coli E24377A hypothetical protein YP_001462720.1 1617622 D 331111 CDS YP_001462721.1 157155182 5588665 complement(1617856..1618305) 1 NC_009801.1 identified by match to protein family HMM PF04657; hypothetical protein 1618305 5588665 EcE24377A_1628 Escherichia coli E24377A hypothetical protein YP_001462721.1 1617856 R 331111 CDS YP_001462722.1 157159424 5588104 complement(1618302..1618883) 1 NC_009801.1 identified by match to protein family HMM PF00583; acetyltransferase 1618883 5588104 EcE24377A_1629 Escherichia coli E24377A acetyltransferase YP_001462722.1 1618302 R 331111 CDS YP_001462723.1 157158447 5586959 1619001..1620038 1 NC_009801.1 identified by match to protein family HMM PF00107; zinc-binding dehydrogenase oxidoreductase 1620038 5586959 EcE24377A_1630 Escherichia coli E24377A zinc-binding dehydrogenase oxidoreductase YP_001462723.1 1619001 D 331111 CDS YP_001462724.1 157158083 5587654 1620236..1620901 1 NC_009801.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; DNA-binding transcriptional regulator 1620901 5587654 EcE24377A_1631 Escherichia coli E24377A DNA-binding transcriptional regulator YP_001462724.1 1620236 D 331111 CDS YP_001462725.1 157156568 5590138 complement(1620937..1623039) 1 NC_009801.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR03304; TonB-dependent receptor 1623039 5590138 EcE24377A_1632 Escherichia coli E24377A TonB-dependent receptor YP_001462725.1 1620937 R 331111 CDS YP_001462726.1 157156104 5588549 1623038..1623133 1 NC_009801.1 identified by glimmer; hypothetical protein 1623133 5588549 EcE24377A_1633 Escherichia coli E24377A hypothetical protein YP_001462726.1 1623038 D 331111 CDS YP_001462727.1 157156405 5586535 1623281..1624342 1 NC_009801.1 hypothetical protein 1624342 5586535 EcE24377A_1634 Escherichia coli E24377A hypothetical protein YP_001462727.1 1623281 D 331111 CDS YP_001462728.1 157154745 5587724 complement(1624457..1625956) 1 NC_009801.1 identified by match to protein family HMM PF00324; L-asparagine permease 1625956 ansP 5587724 ansP Escherichia coli E24377A L-asparagine permease YP_001462728.1 1624457 R 331111 CDS YP_001462729.1 157158787 5587118 complement(1627539..1627685) 1 NC_009801.1 identified by glimmer; hypothetical protein 1627685 5587118 EcE24377A_1637 Escherichia coli E24377A hypothetical protein YP_001462729.1 1627539 R 331111 CDS YP_001462730.1 157158133 5587871 1627947..1630055 1 NC_009801.1 identified by match to protein family HMM PF04524; match to protein family HMM PF06715; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361; ImpA family type VI secretion-associated protein 1630055 5587871 EcE24377A_1638 Escherichia coli E24377A ImpA family type VI secretion-associated protein YP_001462730.1 1627947 D 331111 CDS YP_001462731.1 157156399 5587433 1630123..1634340 1 NC_009801.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; protein rhsD, truncation 1634340 5587433 EcE24377A_1639 Escherichia coli E24377A protein rhsD, truncation YP_001462731.1 1630123 D 331111 CDS YP_001462732.1 157156197 5585903 1634537..1634746 1 NC_009801.1 identified by glimmer; hypothetical protein 1634746 5585903 EcE24377A_1640 Escherichia coli E24377A hypothetical protein YP_001462732.1 1634537 D 331111 CDS YP_001462733.1 157159062 5586827 1636489..1636716 1 NC_009801.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1636716 5586827 EcE24377A_1642 Escherichia coli E24377A 4-oxalocrotonate tautomerase YP_001462733.1 1636489 D 331111 CDS YP_001462734.1 157158743 5586659 complement(1636720..1637289) 1 NC_009801.1 identified by match to protein family HMM PF01613; flavin reductase domain-containing protein 1637289 5586659 EcE24377A_1643 Escherichia coli E24377A flavin reductase domain-containing protein YP_001462734.1 1636720 R 331111 CDS YP_001462735.1 157158247 5588460 1637462..1638307 1 NC_009801.1 identified by match to protein family HMM PF00797; N-hydroxyarylamine O-acetyltransferase 1638307 5588460 EcE24377A_1644 Escherichia coli E24377A N-hydroxyarylamine O-acetyltransferase YP_001462735.1 1637462 D 331111 CDS YP_001462736.1 157157425 5586420 complement(1638403..1639296) 1 NC_009801.1 identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654; hypothetical protein 1639296 5586420 EcE24377A_1645 Escherichia coli E24377A hypothetical protein YP_001462736.1 1638403 R 331111 CDS YP_001462737.1 157156964 5588201 complement(1639375..1640055) 1 NC_009801.1 identified by similarity to SP:P11350; match to protein family HMM PF02665; match to protein family HMM TIGR00351; respiratory nitrate reductase subunit gamma 1640055 narI2 5588201 narI2 Escherichia coli E24377A respiratory nitrate reductase subunit gamma YP_001462737.1 1639375 R 331111 CDS YP_001462738.1 157156278 5586699 complement(1640052..1640747) 1 NC_009801.1 identified by similarity to SP:P19317; match to protein family HMM PF02613; match to protein family HMM TIGR00684; respiratory nitrate reductase 2 delta chain 1640747 narW 5586699 narW Escherichia coli E24377A respiratory nitrate reductase 2 delta chain YP_001462738.1 1640052 R 331111 CDS YP_001462739.1 157159065 5590751 complement(1640747..1642291) 1 NC_009801.1 identified by similarity to SP:P19318; match to protein family HMM TIGR01660; nitrate reductase subunit beta 1642291 narY 5590751 narY Escherichia coli E24377A nitrate reductase subunit beta YP_001462739.1 1640747 R 331111 CDS YP_001462740.1 157155119 5588831 complement(1642257..1646027) 1 NC_009801.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; nitrate reductase subunit alpha 1646027 narZ 5588831 narZ Escherichia coli E24377A nitrate reductase subunit alpha YP_001462740.1 1642257 R 331111 CDS YP_001462741.1 157155872 5587193 complement(1646109..1647497) 1 NC_009801.1 identified by similarity to SP:P37758; match to protein family HMM PF07690; match to protein family HMM TIGR00886; nitrite extrusion protein 2 1647497 narU 5587193 narU Escherichia coli E24377A nitrite extrusion protein 2 YP_001462741.1 1646109 R 331111 CDS YP_001462742.1 157156437 5589263 complement(1647821..1649152) 1 NC_009801.1 identified by similarity to SP:P76123; hypothetical protein 1649152 5589263 EcE24377A_1651 Escherichia coli E24377A hypothetical protein YP_001462742.1 1647821 R 331111 CDS YP_001462743.1 157156070 5589186 complement(1649176..1649466) 1 NC_009801.1 outer membrane porin, truncation 1649466 5589186 EcE24377A_1652 Escherichia coli E24377A outer membrane porin, truncation YP_001462743.1 1649176 R 331111 CDS YP_001462744.1 157156591 5588296 complement(1649725..1650606) 1 NC_009801.1 identified by match to protein family HMM PF00892; hypothetical protein 1650606 5588296 EcE24377A_1653 Escherichia coli E24377A hypothetical protein YP_001462744.1 1649725 R 331111 CDS YP_001462745.1 157157927 5588880 1651474..1653885 1 NC_009801.1 identified by similarity to SP:P24183; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01553; formate dehydrogenase, nitrate inducible subunit alpha, selenocysteine-containing 1653885 fdnG 5588880 fdnG Escherichia coli E24377A formate dehydrogenase, nitrate inducible subunit alpha, selenocysteine-containing YP_001462745.1 1651474 D 331111 CDS YP_001462746.1 157155019 5587328 1653898..1654782 1 NC_009801.1 identified by similarity to SP:P0AAJ3; match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582; formate dehydrogenase, nitrate-inducible, iron-sulfur subunit 1654782 fdnH 5587328 fdnH Escherichia coli E24377A formate dehydrogenase, nitrate-inducible, iron-sulfur subunit YP_001462746.1 1653898 D 331111 CDS YP_001462747.1 157158499 5587918 1654757..1655428 1 NC_009801.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1655428 fdnI 5587918 fdnI Escherichia coli E24377A formate dehydrogenase-N subunit gamma YP_001462747.1 1654757 D 331111 CDS YP_001462748.1 157159120 5588616 complement(1655479..1655763) 1 NC_009801.1 identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607; addiction module antidote protein 1655763 5588616 EcE24377A_1659 Escherichia coli E24377A addiction module antidote protein YP_001462748.1 1655479 R 331111 CDS YP_001462749.1 157157186 5588501 complement(1655910..1656920) 1 NC_009801.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 1656920 5588501 EcE24377A_1660 Escherichia coli E24377A alcohol dehydrogenase YP_001462749.1 1655910 R 331111 CDS YP_001462750.1 157157769 5587318 complement(1657054..1658751) 1 NC_009801.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1658751 sfcA 5587318 sfcA Escherichia coli E24377A malate dehydrogenase YP_001462750.1 1657054 R 331111 CDS YP_001462751.1 157156400 5587371 complement(1658908..1659045) 1 NC_009801.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 1659045 rpsV 5587371 rpsV Escherichia coli E24377A 30S ribosomal subunit S22 YP_001462751.1 1658908 R 331111 CDS YP_001462752.1 157156859 5589532 complement(1659147..1659362) 1 NC_009801.1 identified by similarity to SP:P76127; biofilm-dependent modulation protein 1659362 5589532 EcE24377A_1663 Escherichia coli E24377A biofilm-dependent modulation protein YP_001462752.1 1659147 R 331111 CDS YP_001462753.1 157155256 5589201 1659708..1660139 1 NC_009801.1 identified by match to protein family HMM PF02566; peroxiredoxin OsmC 1660139 osmC 5589201 osmC Escherichia coli E24377A peroxiredoxin OsmC YP_001462753.1 1659708 D 331111 CDS YP_001462754.1 157158451 5590661 complement(1660174..1660944) 1 NC_009801.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate; 3-hydroxybutyrate dehydrogenase 1660944 bdhA 5590661 bdhA Escherichia coli E24377A 3-hydroxybutyrate dehydrogenase YP_001462754.1 1660174 R 331111 CDS YP_001462755.1 157158663 5587179 complement(1660956..1662347) 1 NC_009801.1 identified by match to protein family HMM PF03600; citrate transporter family protein 1662347 5587179 EcE24377A_1666 Escherichia coli E24377A citrate transporter family protein YP_001462755.1 1660956 R 331111 CDS YP_001462756.1 157155775 5587349 complement(1662393..1663316) 1 NC_009801.1 identified by match to protein family HMM PF00725; match to protein family HMM PF02737; 3-hydroxyacyl-CoA dehydrogenase 1663316 5587349 EcE24377A_1667 Escherichia coli E24377A 3-hydroxyacyl-CoA dehydrogenase YP_001462756.1 1662393 R 331111 CDS YP_001462757.1 157156337 5590305 complement(1663306..1664511) 1 NC_009801.1 identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; acetyl-CoA acetyltransferase 1664511 5590305 EcE24377A_1668 Escherichia coli E24377A acetyl-CoA acetyltransferase YP_001462757.1 1663306 R 331111 CDS YP_001462758.1 157157143 5587558 complement(1664521..1665177) 1 NC_009801.1 identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428; 3-oxoacid CoA-transferase subunit B 1665177 5587558 EcE24377A_1669 Escherichia coli E24377A 3-oxoacid CoA-transferase subunit B YP_001462758.1 1664521 R 331111 CDS YP_001462759.1 157157645 5589796 complement(1665180..1665887) 1 NC_009801.1 identified by similarity to SP:Q01103; match to protein family HMM PF01144; match to protein family HMM TIGR02429; 3-oxoadipate CoA-transferase subunit A 1665887 pcaI 5589796 pcaI Escherichia coli E24377A 3-oxoadipate CoA-transferase subunit A YP_001462759.1 1665180 R 331111 CDS YP_001462760.1 157158589 5586744 1666029..1666919 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1666919 5586744 EcE24377A_1671 Escherichia coli E24377A LysR family transcriptional regulator YP_001462760.1 1666029 D 331111 CDS YP_001462761.1 157159094 5590719 complement(1666956..1667882) 1 NC_009801.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; ABC transporter ATP-binding protein 1667882 5590719 EcE24377A_1672 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001462761.1 1666956 R 331111 CDS YP_001462762.1 157155118 5587712 complement(1667875..1668861) 1 NC_009801.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; ABC transporter ATP-binding protein 1668861 5587712 EcE24377A_1673 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001462762.1 1667875 R 331111 CDS YP_001462763.1 157155791 5587241 complement(1668858..1669754) 1 NC_009801.1 identified by similarity to SP:P77463; match to protein family HMM PF00528; ATP-dependent peptide transporter membrane subunit 1669754 5587241 EcE24377A_1674 Escherichia coli E24377A ATP-dependent peptide transporter membrane subunit YP_001462763.1 1668858 R 331111 CDS YP_001462764.1 157156157 5590461 complement(1669751..1670773) 1 NC_009801.1 identified by match to protein family HMM PF00528; ABC transporter permease 1670773 5590461 EcE24377A_1675 Escherichia coli E24377A ABC transporter permease YP_001462764.1 1669751 R 331111 CDS YP_001462765.1 157156046 5588678 complement(1672323..1672904) 1 NC_009801.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis; D-alanyl-D-alanine dipeptidase 1672904 ddpX 5588678 ddpX Escherichia coli E24377A D-alanyl-D-alanine dipeptidase YP_001462765.1 1672323 R 331111 CDS YP_001462766.1 157156733 5585945 complement(1673162..1675585) 1 NC_009801.1 heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase 1675585 dos 5585945 dos Escherichia coli E24377A cAMP phosphodiesterase YP_001462766.1 1673162 R 331111 CDS YP_001462767.1 157158939 5586359 complement(1675586..1676968) 1 NC_009801.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 1676968 5586359 EcE24377A_1679 Escherichia coli E24377A diguanylate cyclase YP_001462767.1 1675586 R 331111 CDS YP_001462768.1 157157249 5586815 complement(1677340..1678659) 1 NC_009801.1 identified by match to protein family HMM PF02638; lipoprotein 1678659 5586815 EcE24377A_1680 Escherichia coli E24377A lipoprotein YP_001462768.1 1677340 R 331111 CDS YP_001462769.1 157155815 5590643 complement(1678790..1680325) 1 NC_009801.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00910; glutamate:gamma aminobutyrate antiporter 1680325 gadC 5590643 gadC Escherichia coli E24377A glutamate:gamma aminobutyrate antiporter YP_001462769.1 1678790 R 331111 CDS YP_001462770.1 157158709 5586277 complement(1680481..1681881) 1 NC_009801.1 identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; glutamate decarboxylase GadB 1681881 gadB 5586277 gadB Escherichia coli E24377A glutamate decarboxylase GadB YP_001462770.1 1680481 R 331111 CDS YP_001462771.1 157156267 5589975 complement(1682000..1682113) 1 NC_009801.1 identified by glimmer; hypothetical protein 1682113 5589975 EcE24377A_1683 Escherichia coli E24377A hypothetical protein YP_001462771.1 1682000 R 331111 CDS YP_001462772.1 157154979 5588445 complement(1682243..1685026) 1 NC_009801.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; M16B family peptidase 1685026 pqqL 5588445 pqqL Escherichia coli E24377A M16B family peptidase YP_001462772.1 1682243 R 331111 CDS YP_001462773.1 157157857 5588528 complement(1685083..1687455) 1 NC_009801.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR03304; TonB-dependent receptor 1687455 5588528 EcE24377A_1685 Escherichia coli E24377A TonB-dependent receptor YP_001462773.1 1685083 R 331111 CDS YP_001462774.1 157156021 5589904 complement(1687493..1689178) 1 NC_009801.1 identified by match to protein family HMM PF00005; match to protein family HMM PF05992; inner membrane ABC transporter ATP-binding protein yddA 1689178 yddA 5589904 yddA Escherichia coli E24377A inner membrane ABC transporter ATP-binding protein yddA YP_001462774.1 1687493 R 331111 CDS YP_001462775.1 157158890 5588058 complement(1689469..1690626) 1 NC_009801.1 ydeM; identified by match to protein family HMM PF04055; radical SAM domain-containing protein 1690626 5588058 EcE24377A_1687 Escherichia coli E24377A radical SAM domain-containing protein YP_001462775.1 1689469 R 331111 CDS YP_001462776.1 157159155 5589407 complement(1692762..1693523) 1 NC_009801.1 regulates the cellular response to acid resistance; transcriptional regulator YdeO 1693523 5589407 EcE24377A_1689 Escherichia coli E24377A transcriptional regulator YdeO YP_001462776.1 1692762 R 331111 CDS YP_001462777.1 157158510 5588253 complement(1694043..1696322) 1 NC_009801.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase; oxidoreductase 1696322 5588253 EcE24377A_1690 Escherichia coli E24377A oxidoreductase YP_001462777.1 1694043 R 331111 CDS YP_001462778.1 157155710 5589282 complement(1696656..1697570) 1 NC_009801.1 identified by similarity to SP:P08191; match to protein family HMM PF00419; match to protein family HMM PF09160; protein FimH-like protein 1697570 5589282 EcE24377A_1691 Escherichia coli E24377A protein FimH-like protein YP_001462778.1 1696656 R 331111 CDS YP_001462779.1 157155269 5588990 complement(1697629..1698132) 1 NC_009801.1 identified by similarity to SP:P08190; match to protein family HMM PF00419; protein fimG-like protein 1698132 5588990 EcE24377A_1692 Escherichia coli E24377A protein fimG-like protein YP_001462779.1 1697629 R 331111 CDS YP_001462780.1 157157024 5587312 complement(1698145..1698675) 1 NC_009801.1 identified by match to protein family HMM PF00419; fimbrial protein 1698675 5587312 EcE24377A_1693 Escherichia coli E24377A fimbrial protein YP_001462780.1 1698145 R 331111 CDS YP_001462781.1 157157168 5588907 complement(1700466..1700915) 1 NC_009801.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; periplasmic pilus chaperone family protein 1700915 5588907 EcE24377A_1695 Escherichia coli E24377A periplasmic pilus chaperone family protein YP_001462781.1 1700466 R 331111 CDS YP_001462782.1 157155473 5588277 1700865..1700966 1 NC_009801.1 identified by glimmer; hypothetical protein 1700966 5588277 EcE24377A_1696 Escherichia coli E24377A hypothetical protein YP_001462782.1 1700865 D 331111 CDS YP_001462783.1 157154964 5588615 1701792..1701917 1 NC_009801.1 identified by glimmer; hypothetical protein 1701917 5588615 EcE24377A_1697 Escherichia coli E24377A hypothetical protein YP_001462783.1 1701792 D 331111 CDS YP_001462784.1 157159048 5590442 complement(1701981..1703201) 1 NC_009801.1 identified by match to protein family HMM PF00263; match to protein family HMM PF03958; type II/III secretion system protein 1703201 5590442 EcE24377A_1698 Escherichia coli E24377A type II/III secretion system protein YP_001462784.1 1701981 R 331111 CDS YP_001462785.1 157158448 5588696 complement(1703211..1704467) 1 NC_009801.1 identified by glimmer; hypothetical protein 1704467 5588696 EcE24377A_1699 Escherichia coli E24377A hypothetical protein YP_001462785.1 1703211 R 331111 CDS YP_001462786.1 157157768 5586764 complement(1704475..1704669) 1 NC_009801.1 identified by glimmer; hypothetical protein 1704669 5586764 EcE24377A_1700 Escherichia coli E24377A hypothetical protein YP_001462786.1 1704475 R 331111 CDS YP_001462787.1 157156626 5590229 1704619..1704897 1 NC_009801.1 identified by glimmer; hypothetical protein 1704897 5590229 EcE24377A_1702 Escherichia coli E24377A hypothetical protein YP_001462787.1 1704619 D 331111 CDS YP_001462788.1 157157690 5586306 complement(1704837..1706165) 1 NC_009801.1 identified by glimmer; hypothetical protein 1706165 5586306 EcE24377A_1701 Escherichia coli E24377A hypothetical protein YP_001462788.1 1704837 R 331111 CDS YP_001462789.1 157156347 5587182 complement(1706221..1706496) 1 NC_009801.1 identified by glimmer; hypothetical protein 1706496 5587182 EcE24377A_1703 Escherichia coli E24377A hypothetical protein YP_001462789.1 1706221 R 331111 CDS YP_001462790.1 157155620 5590431 complement(1706790..1707125) 1 NC_009801.1 identified by glimmer; hypothetical protein 1707125 5590431 EcE24377A_1704 Escherichia coli E24377A hypothetical protein YP_001462790.1 1706790 R 331111 CDS YP_001462791.1 157155532 5587019 complement(1707135..1708331) 1 NC_009801.1 identified by match to protein family HMM PF02486; replication initiation factor family protein 1708331 5587019 EcE24377A_1705 Escherichia coli E24377A replication initiation factor family protein YP_001462791.1 1707135 R 331111 CDS YP_001462792.1 157158090 5586006 complement(1708331..1708528) 1 NC_009801.1 identified by glimmer; hypothetical protein 1708528 5586006 EcE24377A_1706 Escherichia coli E24377A hypothetical protein YP_001462792.1 1708331 R 331111 CDS YP_001462793.1 157157427 5586232 1708663..1708878 1 NC_009801.1 identified by glimmer; hypothetical protein 1708878 5586232 EcE24377A_1707 Escherichia coli E24377A hypothetical protein YP_001462793.1 1708663 D 331111 CDS YP_001462794.1 157156577 5588371 complement(1709205..1709369) 1 NC_009801.1 identified by glimmer; hypothetical protein 1709369 5588371 EcE24377A_1708 Escherichia coli E24377A hypothetical protein YP_001462794.1 1709205 R 331111 CDS YP_001462795.1 157156109 5586312 complement(1709802..1710086) 1 NC_009801.1 identified by similarity to SP:P23873; match to protein family HMM PF01381; DNA-binding transcriptional regulator HipB 1710086 hipB 5586312 hipB Escherichia coli E24377A DNA-binding transcriptional regulator HipB YP_001462795.1 1709802 R 331111 CDS YP_001462796.1 157155821 5590177 complement(1710157..1710249) 1 NC_009801.1 identified by glimmer; hypothetical protein 1710249 5590177 EcE24377A_1710 Escherichia coli E24377A hypothetical protein YP_001462796.1 1710157 R 331111 CDS YP_001462797.1 157155287 5589960 complement(1710277..1714260) 1 NC_009801.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR03304; outer membrane autotransporter domain-containing protein 1714260 5589960 EcE24377A_1711 Escherichia coli E24377A outer membrane autotransporter domain-containing protein YP_001462797.1 1710277 R 331111 CDS YP_001462798.1 157154927 5586283 complement(1714791..1716383) 1 NC_009801.1 identified by similarity to SP:P77432; match to protein family HMM PF00370; match to protein family HMM PF02782; autoinducer-2 (AI-2) kinase 1716383 lsrK 5586283 lsrK Escherichia coli E24377A autoinducer-2 (AI-2) kinase YP_001462798.1 1714791 R 331111 CDS YP_001462799.1 157159022 5588050 complement(1716462..1717415) 1 NC_009801.1 identified by similarity to SP:P76141; match to protein family HMM PF04198; transcriptional repressor LsrR 1717415 lsrR 5588050 lsrR Escherichia coli E24377A transcriptional repressor LsrR YP_001462799.1 1716462 R 331111 CDS YP_001462800.1 157158708 5589425 1717664..1718665 1 NC_009801.1 identified by similarity to SP:P77257; match to protein family HMM PF00005; autoinducer-2 ABC transporter ATP-binding protein LsrA 1718665 lsrA 5589425 lsrA Escherichia coli E24377A autoinducer-2 ABC transporter ATP-binding protein LsrA YP_001462800.1 1717664 D 331111 CDS YP_001462801.1 157157862 5589974 1718662..1719006 1 NC_009801.1 identified by similarity to SP:P0AFS1; autoinducer-2 ABC transporter permease LsrD, truncation 1719006 5589974 EcE24377A_1715 Escherichia coli E24377A autoinducer-2 ABC transporter permease LsrD, truncation YP_001462801.1 1718662 D 331111 CDS YP_001462802.1 157156137 5586185 1719018..1720040 1 NC_009801.1 identified by similarity to SP:P76142; autoinducer-2 ABC transporter periplasmic autoinducer-2-binding protein LsrB 1720040 lsrB 5586185 lsrB Escherichia coli E24377A autoinducer-2 ABC transporter periplasmic autoinducer-2-binding protein LsrB YP_001462802.1 1719018 D 331111 CDS YP_001462803.1 157156373 5587401 1720067..1720942 1 NC_009801.1 identified by similarity to SP:P76143; match to protein family HMM PF01791; aldolase 1720942 lsrF 5587401 lsrF Escherichia coli E24377A aldolase YP_001462803.1 1720067 D 331111 CDS YP_001462804.1 157155186 5590488 1721313..1722071 1 NC_009801.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1722071 tam 5590488 tam Escherichia coli E24377A trans-aconitate 2-methyltransferase YP_001462804.1 1721313 D 331111 CDS YP_001462805.1 157155758 5586172 complement(1722075..1723040) 1 NC_009801.1 identified by match to protein family HMM PF05249; hypothetical protein 1723040 5586172 EcE24377A_1720 Escherichia coli E24377A hypothetical protein YP_001462805.1 1722075 R 331111 CDS YP_001462806.1 157155880 5588308 complement(1723196..1724647) 1 NC_009801.1 catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 1724647 uxaB 5588308 uxaB Escherichia coli E24377A altronate oxidoreductase YP_001462806.1 1723196 R 331111 CDS YP_001462807.1 157158328 5587157 complement(1724874..1726292) 1 NC_009801.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 1726292 5587157 EcE24377A_1722 Escherichia coli E24377A diguanylate cyclase YP_001462807.1 1724874 R 331111 CDS YP_001462808.1 157159073 5586339 complement(1726431..1726790) 1 NC_009801.1 identified by similarity to GB:ABB61754.1; hypothetical protein 1726790 5586339 EcE24377A_1723 Escherichia coli E24377A hypothetical protein YP_001462808.1 1726431 R 331111 CDS YP_001462809.1 157157228 5586584 complement(1726790..1727716) 1 NC_009801.1 catalyzes the formation of glutamate from glutamine; glutaminase 1727716 glsA2 5586584 glsA2 Escherichia coli E24377A glutaminase YP_001462809.1 1726790 R 331111 CDS YP_001462810.1 157158637 5590139 complement(1727780..1729168) 1 NC_009801.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase 1729168 5590139 EcE24377A_1725 Escherichia coli E24377A succinate semialdehyde dehydrogenase YP_001462810.1 1727780 R 331111 CDS YP_001462811.1 157158266 5588084 1729269..1730150 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1730150 5588084 EcE24377A_1726 Escherichia coli E24377A LysR family transcriptional regulator YP_001462811.1 1729269 D 331111 CDS YP_001462812.1 157156734 5588022 complement(1731295..1731414) 1 NC_009801.1 identified by glimmer; hypothetical protein 1731414 5588022 EcE24377A_1728 Escherichia coli E24377A hypothetical protein YP_001462812.1 1731295 R 331111 CDS YP_001462813.1 157159314 5587095 1731491..1732681 1 NC_009801.1 identified by similarity to SP:Q9S3J9; match to protein family HMM PF07690; sugar efflux transporter 1732681 sotB 5587095 sotB Escherichia coli E24377A sugar efflux transporter YP_001462813.1 1731491 D 331111 CDS YP_001462814.1 157159344 5588186 complement(1732706..1733371) 1 NC_009801.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC 1733371 marC 5588186 marC Escherichia coli E24377A multiple drug resistance protein MarC YP_001462814.1 1732706 R 331111 CDS YP_001462815.1 157158832 5588157 1733583..1734017 1 NC_009801.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1734017 marR 5588157 marR Escherichia coli E24377A DNA-binding transcriptional repressor MarR YP_001462815.1 1733583 D 331111 CDS YP_001462816.1 157157625 5586320 1734037..1734420 1 NC_009801.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1734420 marA 5586320 marA Escherichia coli E24377A DNA-binding transcriptional activator MarA YP_001462816.1 1734037 D 331111 CDS YP_001462817.1 157156844 5586502 1734452..1734670 1 NC_009801.1 identified by similarity to SP:P31121; hypothetical protein 1734670 marB 5586502 marB Escherichia coli E24377A hypothetical protein YP_001462817.1 1734452 D 331111 CDS YP_001462818.1 157155768 5590659 complement(1734727..1736166) 1 NC_009801.1 converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase 1736166 celA 5590659 celA Escherichia coli E24377A 6-phospho-beta-glucosidase YP_001462818.1 1734727 R 331111 CDS YP_001462819.1 157155300 5587669 complement(1736191..1737864) 1 NC_009801.1 identified by similarity to SP:P26218; match to protein family HMM PF02264; glucoside specific outer membrane porin BglH-like protein 1737864 5587669 EcE24377A_1736 Escherichia coli E24377A glucoside specific outer membrane porin BglH-like protein YP_001462819.1 1736191 R 331111 CDS YP_001462820.1 157158588 5586327 complement(1737920..1738231) 1 NC_009801.1 identified by match to protein family HMM PF02255; PTS system lactose/cellobiose-specific family IIA subunit 1738231 5586327 EcE24377A_1737 Escherichia coli E24377A PTS system lactose/cellobiose-specific family IIA subunit YP_001462820.1 1737920 R 331111 CDS YP_001462821.1 157157742 5590718 complement(1738259..1739572) 1 NC_009801.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; PTS system lactose/cellobiose family transporter subunit IIC 1739572 5590718 EcE24377A_1738 Escherichia coli E24377A PTS system lactose/cellobiose family transporter subunit IIC YP_001462821.1 1738259 R 331111 CDS YP_001462822.1 157156827 5590203 complement(1739696..1740007) 1 NC_009801.1 identified by match to protein family HMM PF02302; PTS system lactose/cellobiose family transporter subunit IIB 1740007 5590203 EcE24377A_1739 Escherichia coli E24377A PTS system lactose/cellobiose family transporter subunit IIB YP_001462822.1 1739696 R 331111 CDS YP_001462823.1 157156305 5586529 1740206..1740904 1 NC_009801.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 1740904 5586529 EcE24377A_1740 Escherichia coli E24377A GntR family transcriptional regulator YP_001462823.1 1740206 D 331111 CDS YP_001462824.1 157156486 5587266 complement(1740949..1741848) 1 NC_009801.1 identified by match to protein family HMM PF00892; match to protein family HMM PF03151; O-acetylserine/cysteine export protein 1741848 eamA 5587266 eamA Escherichia coli E24377A O-acetylserine/cysteine export protein YP_001462824.1 1740949 R 331111 CDS YP_001462825.1 157155908 5589248 1742043..1743230 1 NC_009801.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 1743230 ydeE 5589248 ydeE Escherichia coli E24377A MFS-type transporter YdeE YP_001462825.1 1742043 D 331111 CDS YP_001462826.1 157155228 5586606 1743357..1743452 1 NC_009801.1 identified by similarity to GB:AAV77284.1; hypothetical protein 1743452 5586606 EcE24377A_1743 Escherichia coli E24377A hypothetical protein YP_001462826.1 1743357 D 331111 CDS YP_001462827.1 157158898 5589529 complement(1743671..1744561) 1 NC_009801.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; hypothetical protein 1744561 5589529 EcE24377A_1744 Escherichia coli E24377A hypothetical protein YP_001462827.1 1743671 R 331111 CDS YP_001462828.1 157154870 5585927 complement(1744816..1745208) 1 NC_009801.1 identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156; hypothetical protein 1745208 5585927 EcE24377A_1745 Escherichia coli E24377A hypothetical protein YP_001462828.1 1744816 R 331111 CDS YP_001462829.1 157159102 5590042 1745484..1746002 1 NC_009801.1 identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199; competence damage-inducible protein A 1746002 5590042 EcE24377A_1746 Escherichia coli E24377A competence damage-inducible protein A YP_001462829.1 1745484 D 331111 CDS YP_001462830.1 157159244 5587928 complement(1746047..1748092) 1 NC_009801.1 identified by similarity to SP:P24171; match to protein family HMM PF01432; dipeptidyl carboxypeptidase II 1748092 dcp 5587928 dcp Escherichia coli E24377A dipeptidyl carboxypeptidase II YP_001462830.1 1746047 R 331111 CDS YP_001462831.1 157158726 5586454 1748229..1748975 1 NC_009801.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1748975 5586454 EcE24377A_1748 Escherichia coli E24377A 3-hydroxy acid dehydrogenase YP_001462831.1 1748229 D 331111 CDS YP_001462832.1 157156864 5586424 1749064..1749750 1 NC_009801.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 1749750 5586424 EcE24377A_1749 Escherichia coli E24377A GntR family transcriptional regulator YP_001462832.1 1749064 D 331111 CDS YP_001462833.1 157156341 5589517 1749928..1750131 1 NC_009801.1 identified by similarity to SP:P64466; hypothetical protein 1750131 5589517 EcE24377A_1750 Escherichia coli E24377A hypothetical protein YP_001462833.1 1749928 D 331111 CDS YP_001462834.1 157155779 5586218 complement(1750167..1751627) 1 NC_009801.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol dehydrogenase 1751627 5586218 EcE24377A_1751 Escherichia coli E24377A mannitol dehydrogenase YP_001462834.1 1750167 R 331111 CDS YP_001462835.1 157155262 5587644 complement(1751716..1752999) 1 NC_009801.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883; inner membrane metabolite transport protein ydfJ 1752999 ydfJ 5587644 ydfJ Escherichia coli E24377A inner membrane metabolite transport protein ydfJ YP_001462835.1 1751716 R 331111 CDS YP_001462836.1 157159097 5588991 1753753..1754019 1 NC_009801.1 identified by similarity to SP:P76154; hypothetical protein 1754019 5588991 EcE24377A_1753 Escherichia coli E24377A hypothetical protein YP_001462836.1 1753753 D 331111 CDS YP_001462837.1 157159297 5588206 1754336..1754926 1 NC_009801.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796; site-specific recombinase resolvase PinR 1754926 pinR 5588206 pinR Escherichia coli E24377A site-specific recombinase resolvase PinR YP_001462837.1 1754336 D 331111 CDS YP_001462838.1 157156180 5589661 complement(1755024..1755599) 1 NC_009801.1 identified by similarity to SP:P03740; match to protein family HMM PF02413; tail fiber assembly protein 1755599 5589661 EcE24377A_1755 Escherichia coli E24377A tail fiber assembly protein YP_001462838.1 1755024 R 331111 CDS YP_001462839.1 157156622 5589165 complement(1756324..1756512) 1 NC_009801.1 hypothetical protein 1756512 5589165 EcE24377A_1756 Escherichia coli E24377A hypothetical protein YP_001462839.1 1756324 R 331111 CDS YP_001462840.1 157158426 5586366 complement(1756610..1758181) 1 NC_009801.1 identified by match to protein family HMM PF03050; IS66 family transposase 1758181 5586366 EcE24377A_1757 Escherichia coli E24377A IS66 family transposase YP_001462840.1 1756610 R 331111 CDS YP_001462841.1 157158973 5586107 complement(1758201..1758548) 1 NC_009801.1 identified by match to protein family HMM PF05717; IS66 family orf2 1758548 5586107 EcE24377A_1758 Escherichia coli E24377A IS66 family orf2 YP_001462841.1 1758201 R 331111 CDS YP_001462842.1 157155301 5586658 complement(1758548..1759012) 1 NC_009801.1 identified by match to protein family HMM PF01527; IS66 family orf1 1759012 5586658 EcE24377A_1759 Escherichia coli E24377A IS66 family orf1 YP_001462842.1 1758548 R 331111 CDS YP_001462843.1 157155656 5586328 complement(1759035..1760573) 1 NC_009801.1 identified by match to protein family HMM PF03050; IS66 family transposase 1760573 5586328 EcE24377A_1760 Escherichia coli E24377A IS66 family transposase YP_001462843.1 1759035 R 331111 CDS YP_001462844.1 157156364 5588096 complement(1760623..1760970) 1 NC_009801.1 identified by match to protein family HMM PF05717; IS66 family orf2 1760970 5588096 EcE24377A_1761 Escherichia coli E24377A IS66 family orf2 YP_001462844.1 1760623 R 331111 CDS YP_001462845.1 157156124 5588364 complement(1760967..1761356) 1 NC_009801.1 identified by match to protein family HMM PF01527; IS66 family orf1 1761356 5588364 EcE24377A_1762 Escherichia coli E24377A IS66 family orf1 YP_001462845.1 1760967 R 331111 CDS YP_001462846.1 157156791 5585912 complement(1761395..1761637) 1 NC_009801.1 identified by match to protein family HMM PF04971; lysis protein S 1761637 5585912 EcE24377A_1763 Escherichia coli E24377A lysis protein S YP_001462846.1 1761395 R 331111 CDS YP_001462847.1 157157405 5588561 complement(1762011..1762142) 1 NC_009801.1 identified by glimmer; hypothetical protein 1762142 5588561 EcE24377A_1764 Escherichia coli E24377A hypothetical protein YP_001462847.1 1762011 R 331111 CDS YP_001462848.1 157158051 5589005 complement(1762391..1762606) 1 NC_009801.1 identified by match to protein family HMM PF00313; cold shock DNA-binding protein 1762606 5589005 EcE24377A_1765 Escherichia coli E24377A cold shock DNA-binding protein YP_001462848.1 1762391 R 331111 CDS YP_001462849.1 157157501 5587104 complement(1763282..1764034) 1 NC_009801.1 identified by match to protein family HMM PF03589; antitermination protein 1764034 5587104 EcE24377A_1766 Escherichia coli E24377A antitermination protein YP_001462849.1 1763282 R 331111 CDS YP_001462850.1 157159274 5588439 complement(1764048..1765097) 1 NC_009801.1 identified by similarity to SP:P76162; match to protein family HMM PF06914; hypothetical protein 1765097 5588439 EcE24377A_1767 Escherichia coli E24377A hypothetical protein YP_001462850.1 1764048 R 331111 CDS YP_001462851.1 157158847 5586093 complement(1765444..1765692) 1 NC_009801.1 hypothetical protein 1765692 5586093 EcE24377A_1768 Escherichia coli E24377A hypothetical protein YP_001462851.1 1765444 R 331111 CDS YP_001462852.1 157158865 5587774 complement(1765757..1765873) 1 NC_009801.1 identified by glimmer; hypothetical protein 1765873 5587774 EcE24377A_1770 Escherichia coli E24377A hypothetical protein YP_001462852.1 1765757 R 331111 CDS YP_001462853.1 157155312 5589591 complement(1766746..1768521) 1 NC_009801.1 hypothetical protein 1768521 5589591 EcE24377A_1771 Escherichia coli E24377A hypothetical protein YP_001462853.1 1766746 R 331111 CDS YP_001462854.1 157154819 5586310 1769148..1769447 1 NC_009801.1 identified by match to protein family HMM PF01527; IS3, transposase orfA 1769447 5586310 EcE24377A_1772 Escherichia coli E24377A IS3, transposase orfA YP_001462854.1 1769148 D 331111 CDS YP_001462855.1 157156866 5587094 complement(1770339..1770530) 1 NC_009801.1 identified by match to protein family HMM PF06163; hypothetical protein 1770530 5587094 EcE24377A_1774 Escherichia coli E24377A hypothetical protein YP_001462855.1 1770339 R 331111 CDS YP_001462856.1 157157880 5588069 complement(1770571..1771536) 1 NC_009801.1 identified by similarity to SP:P03688; phage O family protein 1771536 5588069 EcE24377A_1775 Escherichia coli E24377A phage O family protein YP_001462856.1 1770571 R 331111 CDS YP_001462857.1 157158428 5588407 complement(1771517..1772038) 1 NC_009801.1 identified by similarity to GB:BAB35190.1; match to protein family HMM PF06254; hypothetical protein 1772038 5588407 EcE24377A_1776 Escherichia coli E24377A hypothetical protein YP_001462857.1 1771517 R 331111 CDS YP_001462858.1 157155456 5589208 complement(1772022..1772252) 1 NC_009801.1 identified by similarity to SP:P06965; DNA-binding transcriptional regulator DicC 1772252 dicC 5589208 dicC Escherichia coli E24377A DNA-binding transcriptional regulator DicC YP_001462858.1 1772022 R 331111 CDS YP_001462859.1 157156209 5590739 complement(1772711..1772803) 1 NC_009801.1 identified by glimmer; hypothetical protein 1772803 5590739 EcE24377A_1778 Escherichia coli E24377A hypothetical protein YP_001462859.1 1772711 R 331111 CDS YP_001462860.1 157159453 5587801 1772910..1773065 1 NC_009801.1 identified by match to protein family HMM PF07151; hypothetical protein 1773065 5587801 EcE24377A_1779 Escherichia coli E24377A hypothetical protein YP_001462860.1 1772910 D 331111 CDS YP_001462861.1 157154836 5588340 complement(1773863..1774018) 1 NC_009801.1 identified by glimmer; hypothetical protein 1774018 5588340 EcE24377A_1780 Escherichia coli E24377A hypothetical protein YP_001462861.1 1773863 R 331111 CDS YP_001462862.1 157157997 5586183 1774024..1774317 1 NC_009801.1 identified by similarity to SP:P09557; match to protein family HMM PF05358; division inhibition protein DicB 1774317 dicB 5586183 dicB Escherichia coli E24377A division inhibition protein DicB YP_001462862.1 1774024 D 331111 CDS YP_001462863.1 157158820 5588335 1774314..1774505 1 NC_009801.1 identified by match to protein family HMM PF07358; hypothetical protein 1774505 5588335 EcE24377A_1782 Escherichia coli E24377A hypothetical protein YP_001462863.1 1774314 D 331111 CDS YP_001462864.1 157156186 5590263 1774599..1777076 1 NC_009801.1 identified by match to protein family HMM PF00929; exonuclease 1777076 5590263 EcE24377A_1784 Escherichia coli E24377A exonuclease YP_001462864.1 1774599 D 331111 CDS YP_001462865.1 157156740 5589122 complement(1777073..1777165) 1 NC_009801.1 identified by glimmer; hypothetical protein 1777165 5589122 EcE24377A_1783 Escherichia coli E24377A hypothetical protein YP_001462865.1 1777073 R 331111 CDS YP_001462866.1 157155307 5587329 1777149..1777400 1 NC_009801.1 identified by match to protein family HMM PF06806; phage excisionase 1777400 5587329 EcE24377A_1785 Escherichia coli E24377A phage excisionase YP_001462866.1 1777149 D 331111 CDS YP_001462867.1 157159384 5586343 1777435..1778715 1 NC_009801.1 identified by match to protein family HMM PF00589; phage integrase site specific recombinase 1778715 5586343 EcE24377A_1786 Escherichia coli E24377A phage integrase site specific recombinase YP_001462867.1 1777435 D 331111 CDS YP_001462868.1 157158834 5588272 complement(1778903..1779922) 1 NC_009801.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; dehydrogenase 1779922 rspB 5588272 rspB Escherichia coli E24377A dehydrogenase YP_001462868.1 1778903 R 331111 CDS YP_001462869.1 157155324 5585915 complement(1779934..1781148) 1 NC_009801.1 identified by similarity to SP:P38104; match to protein family HMM PF01188; match to protein family HMM PF02746; starvation-sensing protein RspA 1781148 rspA1 5585915 rspA1 Escherichia coli E24377A starvation-sensing protein RspA YP_001462869.1 1779934 R 331111 CDS YP_001462870.1 157154779 5589863 complement(1781354..1781680) 1 NC_009801.1 identified by match to protein family HMM PF02694; hypothetical protein 1781680 5589863 EcE24377A_1789 Escherichia coli E24377A hypothetical protein YP_001462870.1 1781354 R 331111 CDS YP_001462871.1 157156696 5590144 1781815..1782156 1 NC_009801.1 identified by match to protein family HMM PF06932; hypothetical protein 1782156 5590144 EcE24377A_1790 Escherichia coli E24377A hypothetical protein YP_001462871.1 1781815 D 331111 CDS YP_001462872.1 157156145 5588524 1782191..1782751 1 NC_009801.1 identified by similarity to SP:P0A951; match to protein family HMM PF00583; diamine N-acetyltransferase 1782751 speG 5588524 speG Escherichia coli E24377A diamine N-acetyltransferase YP_001462872.1 1782191 D 331111 CDS YP_001462873.1 157157422 5590094 complement(1782754..1783500) 1 NC_009801.1 identified by match to protein family HMM PF06788; hypothetical protein 1783500 5590094 EcE24377A_1792 Escherichia coli E24377A hypothetical protein YP_001462873.1 1782754 R 331111 CDS YP_001462874.1 157159403 5589402 1783572..1783877 1 NC_009801.1 identified by match to protein family HMM PF06649; hypothetical protein 1783877 5589402 EcE24377A_1793 Escherichia coli E24377A hypothetical protein YP_001462874.1 1783572 D 331111 CDS YP_001462875.1 157158793 5586527 1784076..1786502 1 NC_009801.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166; anaerobic dimethyl sulfoxide reductase, A subunit YnfE 1786502 ynfE 5586527 ynfE Escherichia coli E24377A anaerobic dimethyl sulfoxide reductase, A subunit YnfE YP_001462875.1 1784076 D 331111 CDS YP_001462876.1 157158364 5588067 1786563..1788986 1 NC_009801.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166; anaerobic dimethyl sulfoxide reductase subunit A 1788986 5588067 EcE24377A_1795 Escherichia coli E24377A anaerobic dimethyl sulfoxide reductase subunit A YP_001462876.1 1786563 D 331111 CDS YP_001462877.1 157157756 5587285 1788997..1789614 1 NC_009801.1 identified by similarity to SP:P18776; match to protein family HMM PF00037; match to protein family HMM TIGR02951; dimethylsulfoxide reductase subunit B 1789614 dmsB2 5587285 dmsB2 Escherichia coli E24377A dimethylsulfoxide reductase subunit B YP_001462877.1 1788997 D 331111 CDS YP_001462878.1 157157638 5587682 1789616..1790470 1 NC_009801.1 identified by match to protein family HMM PF04976; anaerobic dimethyl sulfoxide reductase subunit C 1790470 dmsC2 5587682 dmsC2 Escherichia coli E24377A anaerobic dimethyl sulfoxide reductase subunit C YP_001462878.1 1789616 D 331111 CDS YP_001462879.1 157155231 5589801 1790513..1791127 1 NC_009801.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1791127 dmsD 5589801 dmsD Escherichia coli E24377A twin-argninine leader-binding protein DmsD YP_001462879.1 1790513 D 331111 CDS YP_001462880.1 157155412 5589110 1791323..1792579 1 NC_009801.1 identified by match to protein family HMM PF00654; voltage-gated ClC-type chloride channel ClcB 1792579 5589110 EcE24377A_1800 Escherichia coli E24377A voltage-gated ClC-type chloride channel ClcB YP_001462880.1 1791323 D 331111 CDS YP_001462881.1 157155961 5590592 complement(1792532..1793227) 1 NC_009801.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1793227 5590592 EcE24377A_1799 Escherichia coli E24377A dithiobiotin synthetase YP_001462881.1 1792532 R 331111 CDS YP_001462882.1 157154987 5589327 complement(1793352..1794572) 1 NC_009801.1 identified by similarity to SP:P50456; match to protein family HMM PF00480; transcriptional regulator Mic 1794572 mic 5589327 mic Escherichia coli E24377A transcriptional regulator Mic YP_001462882.1 1793352 R 331111 CDS YP_001462883.1 157157346 5586990 complement(1794707..1795600) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1795600 5586990 EcE24377A_1802 Escherichia coli E24377A LysR family transcriptional regulator YP_001462883.1 1794707 R 331111 CDS YP_001462884.1 157159248 5589626 1795707..1796960 1 NC_009801.1 identified by match to protein family HMM PF07690; major facilitator family transporter 1796960 ynfM 5589626 ynfM Escherichia coli E24377A major facilitator family transporter YP_001462884.1 1795707 D 331111 CDS YP_001462885.1 157156360 5590881 1797357..1797692 1 NC_009801.1 required for growth and survival under moderately acid conditions; acid shock protein 1797692 5590881 EcE24377A_1804 Escherichia coli E24377A acid shock protein YP_001462885.1 1797357 D 331111 CDS YP_001462886.1 157158557 5590726 1797968..1798789 1 NC_009801.1 identified by match to protein family HMM PF00089; S1A family peptidase 1798789 5590726 EcE24377A_1805 Escherichia coli E24377A S1A family peptidase YP_001462886.1 1797968 D 331111 CDS YP_001462887.1 157155397 5589814 complement(1798828..1799157) 1 NC_009801.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI 1799157 mdtI 5589814 mdtI Escherichia coli E24377A multidrug efflux system protein MdtI YP_001462887.1 1798828 R 331111 CDS YP_001462888.1 157158482 5586220 complement(1799144..1799509) 1 NC_009801.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ 1799509 mdtJ 5586220 mdtJ Escherichia coli E24377A multidrug efflux system protein MdtJ YP_001462888.1 1799144 R 331111 CDS YP_001462889.1 157155130 5586790 1799921..1800955 1 NC_009801.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transporter 1800955 tqsA 5586790 tqsA Escherichia coli E24377A transporter YP_001462889.1 1799921 D 331111 CDS YP_001462890.1 157155678 5586855 complement(1800980..1802368) 1 NC_009801.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 1802368 pntB 5586855 pntB Escherichia coli E24377A pyridine nucleotide transhydrogenase YP_001462890.1 1800980 R 331111 CDS YP_001462891.1 157158166 5589805 complement(1802379..1803911) 1 NC_009801.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 1803911 pntA 5589805 pntA Escherichia coli E24377A NAD(P) transhydrogenase subunit alpha YP_001462891.1 1802379 R 331111 CDS YP_001462892.1 157156317 5589002 1804335..1804445 1 NC_009801.1 identified by glimmer; hypothetical protein 1804445 5589002 EcE24377A_1811 Escherichia coli E24377A hypothetical protein YP_001462892.1 1804335 D 331111 CDS YP_001462893.1 157159019 5586907 1804435..1805379 1 NC_009801.1 identified by match to protein family HMM PF07338; hypothetical protein 1805379 ydgH 5586907 ydgH Escherichia coli E24377A hypothetical protein YP_001462893.1 1804435 D 331111 CDS YP_001462894.1 157157155 5587839 1805565..1806947 1 NC_009801.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905; arginine/ornithine antiporter 1806947 arcD 5587839 arcD Escherichia coli E24377A arginine/ornithine antiporter YP_001462894.1 1805565 D 331111 CDS YP_001462895.1 157154921 5588797 1806984..1807706 1 NC_009801.1 identified by match to protein family HMM PF00106; short chain dehydrogenase 1807706 5588797 EcE24377A_1815 Escherichia coli E24377A short chain dehydrogenase YP_001462895.1 1806984 D 331111 CDS YP_001462896.1 157156106 5587027 complement(1807703..1808038) 1 NC_009801.1 identified by match to protein family HMM PF06942; hypothetical protein 1808038 5587027 EcE24377A_1814 Escherichia coli E24377A hypothetical protein YP_001462896.1 1807703 R 331111 CDS YP_001462897.1 157158097 5589864 1808167..1808886 1 NC_009801.1 response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1808886 rstA 5589864 rstA Escherichia coli E24377A DNA-binding transcriptional regulator RstA YP_001462897.1 1808167 D 331111 CDS YP_001462898.1 157157469 5586209 1808890..1810191 1 NC_009801.1 identified by similarity to SP:P18392; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor protein RstB 1810191 rstB 5586209 rstB Escherichia coli E24377A sensor protein RstB YP_001462898.1 1808890 D 331111 CDS YP_001462899.1 157159451 5590049 1810267..1811196 1 NC_009801.1 binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1811196 tus 5590049 tus Escherichia coli E24377A DNA replication terminus site-binding protein YP_001462899.1 1810267 D 331111 CDS YP_001462900.1 157159081 5586726 complement(1811193..1812596) 1 NC_009801.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1812596 fumC 5586726 fumC Escherichia coli E24377A fumarate hydratase YP_001462900.1 1811193 R 331111 CDS YP_001462901.1 157155853 5588885 complement(1812738..1814384) 1 NC_009801.1 identified by similarity to SP:P0AC33; match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723; fumarate hydratase 1814384 fumA 5588885 fumA Escherichia coli E24377A fumarate hydratase YP_001462901.1 1812738 R 331111 CDS YP_001462902.1 157155328 5587221 1814583..1815758 1 NC_009801.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218; mannose-6-phosphate isomerase 1815758 manA 5587221 manA Escherichia coli E24377A mannose-6-phosphate isomerase YP_001462902.1 1814583 D 331111 CDS YP_001462903.1 157154970 5588054 1815859..1817367 1 NC_009801.1 identified by match to protein family HMM PF06097; hypothetical protein 1817367 5588054 EcE24377A_1822 Escherichia coli E24377A hypothetical protein YP_001462903.1 1815859 D 331111 CDS YP_001462904.1 157158734 5586944 complement(1817412..1818677) 1 NC_009801.1 identified by similarity to SP:Q47706; match to protein family HMM PF03573; outer membrane porin protein 1818677 uidC 5586944 uidC Escherichia coli E24377A outer membrane porin protein YP_001462904.1 1817412 R 331111 CDS YP_001462905.1 157156112 5585913 complement(1818716..1820089) 1 NC_009801.1 identified by similarity to SP:P30868; match to protein family HMM PF07690; match to protein family HMM TIGR00792; glucuronide transporter 1820089 uidB 5585913 uidB Escherichia coli E24377A glucuronide transporter YP_001462905.1 1818716 R 331111 CDS YP_001462906.1 157158494 5590771 complement(1820086..1821897) 1 NC_009801.1 identified by similarity to SP:P05804; match to protein family HMM PF00703; match to protein family HMM PF02836; match to protein family HMM PF02837; beta-D-glucuronidase 1821897 uidA 5590771 uidA Escherichia coli E24377A beta-D-glucuronidase YP_001462906.1 1820086 R 331111 CDS YP_001462907.1 157156031 5588133 complement(1822286..1822876) 1 NC_009801.1 identified by match to protein family HMM PF00440; transcriptional regulator UidR 1822876 uidR 5588133 uidR Escherichia coli E24377A transcriptional regulator UidR YP_001462907.1 1822286 R 331111 CDS YP_001462908.1 157156531 5585929 complement(1823105..1823872) 1 NC_009801.1 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 1823872 5585929 EcE24377A_1827 Escherichia coli E24377A 7-alpha-hydroxysteroid dehydrogenase YP_001462908.1 1823105 R 331111 CDS YP_001462909.1 157155002 5590226 complement(1823984..1825012) 1 NC_009801.1 regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI 1825012 malI 5590226 malI Escherichia coli E24377A DNA-binding transcriptional repressor MalI YP_001462909.1 1823984 R 331111 CDS YP_001462910.1 157155518 5586215 1825187..1826779 1 NC_009801.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1826779 malX 5586215 malX Escherichia coli E24377A bifunctional PTS system maltose and glucose-specific transporter subunits IICB YP_001462910.1 1825187 D 331111 CDS YP_001462911.1 157159140 5590046 1826789..1827961 1 NC_009801.1 identified by similarity to SP:P23256; match to protein family HMM PF00155; MalY protein 1827961 malY 5590046 malY Escherichia coli E24377A MalY protein YP_001462911.1 1826789 D 331111 CDS YP_001462912.1 157155031 5587676 1828065..1829066 1 NC_009801.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 1829066 add 5587676 add Escherichia coli E24377A adenosine deaminase YP_001462912.1 1828065 D 331111 CDS YP_001462913.1 157158125 5589358 complement(1829101..1830180) 1 NC_009801.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase 1830180 5589358 EcE24377A_1832 Escherichia coli E24377A oxidoreductase YP_001462913.1 1829101 R 331111 CDS YP_001462914.1 157158791 5590856 1830782..1830997 1 NC_009801.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1830997 5590856 EcE24377A_1833 Escherichia coli E24377A oriC-binding nucleoid-associated protein YP_001462914.1 1830782 D 331111 CDS YP_001462915.1 157158648 5587976 1831083..1831523 1 NC_009801.1 hypothetical protein 1831523 5587976 EcE24377A_1834 Escherichia coli E24377A hypothetical protein YP_001462915.1 1831083 D 331111 CDS YP_001462916.1 157159316 5588750 1831600..1832181 1 NC_009801.1 identified by match to protein family HMM PF02508; match to protein family HMM TIGR01943; Na(+)-translocating NADH-quinone reductase subunit E 1832181 rnfA 5588750 rnfA Escherichia coli E24377A Na(+)-translocating NADH-quinone reductase subunit E YP_001462916.1 1831600 D 331111 CDS YP_001462917.1 157157455 5590664 1832181..1832759 1 NC_009801.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1832759 rnfB 5590664 rnfB Escherichia coli E24377A electron transport complex protein RnfB YP_001462917.1 1832181 D 331111 CDS YP_001462918.1 157157957 5586392 1832752..1834974 1 NC_009801.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1834974 rnfC 5586392 rnfC Escherichia coli E24377A electron transport complex protein RnfC YP_001462918.1 1832752 D 331111 CDS YP_001462919.1 157156129 5589332 1834975..1836033 1 NC_009801.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1836033 rnfD 5589332 rnfD Escherichia coli E24377A electron transport complex protein RnfD YP_001462919.1 1834975 D 331111 CDS YP_001462920.1 157156662 5586480 1836037..1836657 1 NC_009801.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1836657 rnfG 5586480 rnfG Escherichia coli E24377A electron transport complex protein RnfG YP_001462920.1 1836037 D 331111 CDS YP_001462921.1 157156445 5590687 1836661..1837356 1 NC_009801.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 1837356 rnfE 5590687 rnfE Escherichia coli E24377A electron transport complex protein RsxE YP_001462921.1 1836661 D 331111 CDS YP_001462922.1 157154782 5587487 complement(1836945..1837655) 1 NC_009801.1 identified by glimmer; hypothetical protein 1837655 5587487 EcE24377A_1840 Escherichia coli E24377A hypothetical protein YP_001462922.1 1836945 R 331111 CDS YP_001462923.1 157157628 5586027 1837356..1837991 1 NC_009801.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1837991 nth 5586027 nth Escherichia coli E24377A endonuclease III YP_001462923.1 1837356 D 331111 CDS YP_001462924.1 157159211 5589541 complement(1838545..1838655) 1 NC_009801.1 identified by glimmer; hypothetical protein 1838655 5589541 EcE24377A_1843 Escherichia coli E24377A hypothetical protein YP_001462924.1 1838545 R 331111 CDS YP_001462925.1 157156303 5588859 1838603..1840105 1 NC_009801.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 1840105 tppB 5588859 tppB Escherichia coli E24377A tripeptide transporter permease YP_001462925.1 1838603 D 331111 CDS YP_001462926.1 157157529 5587772 1840211..1840816 1 NC_009801.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathionine S-transferase 1840816 5587772 EcE24377A_1845 Escherichia coli E24377A glutathionine S-transferase YP_001462926.1 1840211 D 331111 CDS YP_001462927.1 157158005 5589515 complement(1840860..1841720) 1 NC_009801.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1841720 pdxY 5589515 pdxY Escherichia coli E24377A pyridoxamine kinase YP_001462927.1 1840860 R 331111 CDS YP_001462928.1 157157482 5590347 complement(1841782..1843056) 1 NC_009801.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1843056 tyrS 5590347 tyrS Escherichia coli E24377A tyrosyl-tRNA synthetase YP_001462928.1 1841782 R 331111 CDS YP_001462929.1 157159396 5587953 complement(1843185..1843841) 1 NC_009801.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 1843841 pdxH 5587953 pdxH Escherichia coli E24377A pyridoxamine 5'-phosphate oxidase YP_001462929.1 1843185 R 331111 CDS YP_001462930.1 157158848 5589641 complement(1843900..1844223) 1 NC_009801.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor 1844223 5589641 EcE24377A_1849 Escherichia coli E24377A lysozyme inhibitor YP_001462930.1 1843900 R 331111 CDS YP_001462931.1 157155348 5587775 complement(1844327..1845436) 1 NC_009801.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1845436 anmK 5587775 anmK Escherichia coli E24377A anhydro-N-acetylmuramic acid kinase YP_001462931.1 1844327 R 331111 CDS YP_001462932.1 157154835 5590698 1845710..1846177 1 NC_009801.1 identified by similarity to SP:P0A1X0; match to protein family HMM PF05433; outer membrane lipoprotein SlyB 1846177 slyB 5590698 slyB Escherichia coli E24377A outer membrane lipoprotein SlyB YP_001462932.1 1845710 D 331111 CDS YP_001462933.1 157157476 5586230 complement(1846224..1846658) 1 NC_009801.1 Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA 1846658 5586230 EcE24377A_1852 Escherichia coli E24377A transcriptional regulator SlyA YP_001462933.1 1846224 R 331111 CDS YP_001462934.1 157156214 5587578 complement(1846683..1846802) 1 NC_009801.1 identified by glimmer; hypothetical protein 1846802 5587578 EcE24377A_1853 Escherichia coli E24377A hypothetical protein YP_001462934.1 1846683 R 331111 CDS YP_001462935.1 157155248 5586417 1846859..1847095 1 NC_009801.1 identified by match to protein family HMM PF07869; hypothetical protein 1847095 5586417 EcE24377A_1854 Escherichia coli E24377A hypothetical protein YP_001462935.1 1846859 D 331111 CDS YP_001462936.1 157155760 5590450 1847098..1847955 1 NC_009801.1 identified by match to protein family HMM PF00529; MFP family transporter 1847955 5590450 EcE24377A_1855 Escherichia coli E24377A MFP family transporter YP_001462936.1 1847098 D 331111 CDS YP_001462937.1 157158986 5589049 1847955..1849967 1 NC_009801.1 identified by match to protein family HMM PF04632; fusaric acid resistance domain-containing protein 1849967 5589049 EcE24377A_1856 Escherichia coli E24377A fusaric acid resistance domain-containing protein YP_001462937.1 1847955 D 331111 CDS YP_001462938.1 157157140 5588209 complement(1849968..1850489) 1 NC_009801.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase 1850489 sodC 5588209 sodC Escherichia coli E24377A superoxide dismutase YP_001462938.1 1849968 R 331111 CDS YP_001462939.1 157157397 5589772 complement(1850570..1851466) 1 NC_009801.1 identified by similarity to SP:P76187; match to protein family HMM PF00248; oxidoreductase YdhF 1851466 ydhF 5589772 ydhF Escherichia coli E24377A oxidoreductase YdhF YP_001462939.1 1850570 R 331111 CDS YP_001462940.1 157157916 5589508 1851526..1851645 1 NC_009801.1 identified by glimmer; hypothetical protein 1851645 5589508 EcE24377A_1859 Escherichia coli E24377A hypothetical protein YP_001462940.1 1851526 D 331111 CDS YP_001462941.1 157156310 5590472 1851857..1852456 1 NC_009801.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1852456 5590472 EcE24377A_1860 Escherichia coli E24377A TetR family transcriptional regulator YP_001462941.1 1851857 D 331111 CDS YP_001462942.1 157156831 5586694 1852493..1853590 1 NC_009801.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1853590 nemA 5586694 nemA Escherichia coli E24377A N-ethylmaleimide reductase YP_001462942.1 1852493 D 331111 CDS YP_001462943.1 157158384 5586412 1853671..1854078 1 NC_009801.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1854078 gloA 5586412 gloA Escherichia coli E24377A glyoxalase I YP_001462943.1 1853671 D 331111 CDS YP_001462944.1 157159164 5587438 1854181..1854828 1 NC_009801.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1854828 rnt 5587438 rnt Escherichia coli E24377A ribonuclease T YP_001462944.1 1854181 D 331111 CDS YP_001462945.1 157157138 5588198 complement(1854859..1854969) 1 NC_009801.1 identified by glimmer; hypothetical protein 1854969 5588198 EcE24377A_1864 Escherichia coli E24377A hypothetical protein YP_001462945.1 1854859 R 331111 CDS YP_001462946.1 157158101 5589921 1854921..1859537 1 NC_009801.1 similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli; ATP-dependent helicase Lhr 1859537 lhr 5589921 lhr Escherichia coli E24377A ATP-dependent helicase Lhr YP_001462946.1 1854921 D 331111 CDS YP_001462947.1 157155524 5586810 complement(1859588..1859935) 1 NC_009801.1 identified by similarity to SP:P0AC69; match to protein family HMM PF00462; match to protein family HMM TIGR00365; hypothetical protein 1859935 5586810 EcE24377A_1866 Escherichia coli E24377A hypothetical protein YP_001462947.1 1859588 R 331111 CDS YP_001462948.1 157156841 5590757 complement(1860017..1860169) 1 NC_009801.1 identified by glimmer; hypothetical protein 1860169 5590757 EcE24377A_1867 Escherichia coli E24377A hypothetical protein YP_001462948.1 1860017 R 331111 CDS YP_001462949.1 157158934 5589359 1860269..1861084 1 NC_009801.1 identified by match to protein family HMM PF00877; NlpC/P60 family protein 1861084 5589359 EcE24377A_1868 Escherichia coli E24377A NlpC/P60 family protein YP_001462949.1 1860269 D 331111 CDS YP_001462950.1 157154847 5586139 1861212..1861793 1 NC_009801.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1861793 sodB 5586139 sodB Escherichia coli E24377A superoxide dismutase YP_001462950.1 1861212 D 331111 CDS YP_001462951.1 157158785 5590613 complement(1861939..1863108) 1 NC_009801.1 identified by match to protein family HMM PF07690; major facilitator transporter 1863108 5590613 EcE24377A_1870 Escherichia coli E24377A major facilitator transporter YP_001462951.1 1861939 R 331111 CDS YP_001462952.1 157159444 5587218 complement(1863274..1863393) 1 NC_009801.1 identified by glimmer; membrane protein 1863393 5587218 EcE24377A_1871 Escherichia coli E24377A membrane protein YP_001462952.1 1863274 R 331111 CDS YP_001462953.1 157157434 5585976 1863662..1864687 1 NC_009801.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1864687 purR 5585976 purR Escherichia coli E24377A DNA-binding transcriptional repressor PurR YP_001462953.1 1863662 D 331111 CDS YP_001462954.1 157158107 5587628 complement(1864684..1865616) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator 1865616 5587628 EcE24377A_1872 Escherichia coli E24377A DNA-binding transcriptional regulator YP_001462954.1 1864684 R 331111 CDS YP_001462955.1 157155479 5587622 1865729..1866940 1 NC_009801.1 uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1866940 ydhC 5587622 ydhC Escherichia coli E24377A inner membrane transport protein YdhC YP_001462955.1 1865729 D 331111 CDS YP_001462956.1 157155437 5589234 1867231..1868379 1 NC_009801.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 1868379 cfa 5589234 cfa Escherichia coli E24377A cyclopropane-fatty-acyl-phospholipid synthase YP_001462956.1 1867231 D 331111 CDS YP_001462957.1 157154765 5590853 complement(1868419..1869060) 1 NC_009801.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1869060 ribE 5590853 ribE Escherichia coli E24377A riboflavin synthase subunit alpha YP_001462957.1 1868419 R 331111 CDS YP_001462958.1 157155199 5587923 1869275..1870648 1 NC_009801.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1870648 5587923 EcE24377A_1877 Escherichia coli E24377A multidrug efflux protein YP_001462958.1 1869275 D 331111 CDS YP_001462959.1 157156334 5587846 complement(1870689..1871945) 1 NC_009801.1 hypothetical protein 1871945 5587846 EcE24377A_1878 Escherichia coli E24377A hypothetical protein YP_001462959.1 1870689 R 331111 CDS YP_001462960.1 157158008 5588314 complement(1872147..1872242) 1 NC_009801.1 identified by glimmer; hypothetical protein 1872242 5588314 EcE24377A_1879 Escherichia coli E24377A hypothetical protein YP_001462960.1 1872147 R 331111 CDS YP_001462961.1 157157363 5587516 1872518..1872823 1 NC_009801.1 identified by similarity to GB:AAV79142.1; match to protein family HMM PF08803; hypothetical protein 1872823 5587516 EcE24377A_1882 Escherichia coli E24377A hypothetical protein YP_001462961.1 1872518 D 331111 CDS YP_001462962.1 157154858 5588463 complement(1874565..1875377) 1 NC_009801.1 identified by similarity to GB:AAZ88190.1; hypothetical protein 1875377 5588463 EcE24377A_1884 Escherichia coli E24377A hypothetical protein YP_001462962.1 1874565 R 331111 CDS YP_001462963.1 157156596 5590699 complement(1875381..1876166) 1 NC_009801.1 identified by match to protein family HMM PF01292; nickel-dependent hydrogenase, b-type cytochrome subunit 1876166 5590699 EcE24377A_1885 Escherichia coli E24377A nickel-dependent hydrogenase, b-type cytochrome subunit YP_001462963.1 1875381 R 331111 CDS YP_001462964.1 157157694 5589501 complement(1876163..1876882) 1 NC_009801.1 identified by match to protein family HMM PF00037; (Fe-S)-binding protein 1876882 5589501 EcE24377A_1886 Escherichia coli E24377A (Fe-S)-binding protein YP_001462964.1 1876163 R 331111 CDS YP_001462965.1 157155753 5587113 complement(1876895..1877542) 1 NC_009801.1 identified by similarity to GB:AAZ88187.1; hypothetical protein 1877542 5587113 EcE24377A_1887 Escherichia coli E24377A hypothetical protein YP_001462965.1 1876895 R 331111 CDS YP_001462966.1 157155246 5589952 complement(1877546..1879648) 1 NC_009801.1 identified by match to protein family HMM PF01314; match to protein family HMM PF02730; oxidoreductase 1879648 5589952 EcE24377A_1888 Escherichia coli E24377A oxidoreductase YP_001462966.1 1877546 R 331111 CDS YP_001462967.1 157156899 5585906 complement(1879669..1880295) 1 NC_009801.1 identified by match to protein family HMM PF00037; hypothetical protein 1880295 5585906 EcE24377A_1889 Escherichia coli E24377A hypothetical protein YP_001462967.1 1879669 R 331111 CDS YP_001462968.1 157156314 5589031 1880323..1880460 1 NC_009801.1 identified by glimmer; hypothetical protein 1880460 5589031 EcE24377A_1890 Escherichia coli E24377A hypothetical protein YP_001462968.1 1880323 D 331111 CDS YP_001462969.1 157156095 5589977 complement(1880751..1880960) 1 NC_009801.1 hypothetical protein 1880960 5589977 EcE24377A_1891 Escherichia coli E24377A hypothetical protein YP_001462969.1 1880751 R 331111 CDS YP_001462970.1 157157921 5586596 1881517..1882929 1 NC_009801.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1882929 pykF 5586596 pykF Escherichia coli E24377A pyruvate kinase YP_001462970.1 1881517 D 331111 CDS YP_001462971.1 157157328 5586507 1883240..1883476 1 NC_009801.1 identified by similarity to SP:P69776; match to protein family HMM PF04728; major outer membrane lipoprotein 1883476 lpp 5586507 lpp Escherichia coli E24377A major outer membrane lipoprotein YP_001462971.1 1883240 D 331111 CDS YP_001462972.1 157159013 5589750 complement(1883540..1884544) 1 NC_009801.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734; LysM/ErfK/YbiS/YcfS/YnhG family protein 1884544 5589750 EcE24377A_1894 Escherichia coli E24377A LysM/ErfK/YbiS/YcfS/YnhG family protein YP_001462972.1 1883540 R 331111 CDS YP_001462973.1 157158751 5588863 complement(1884693..1885109) 1 NC_009801.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE 1885109 sufE 5588863 sufE Escherichia coli E24377A cysteine desufuration protein SufE YP_001462973.1 1884693 R 331111 CDS YP_001462974.1 157158206 5586353 complement(1885122..1886342) 1 NC_009801.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase 1886342 sufS 5586353 sufS Escherichia coli E24377A bifunctional cysteine desulfurase/selenocysteine lyase YP_001462974.1 1885122 R 331111 CDS YP_001462975.1 157154860 5589674 complement(1886339..1887610) 1 NC_009801.1 with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD 1887610 sufD 5589674 sufD Escherichia coli E24377A cysteine desulfurase activator complex subunit SufD YP_001462975.1 1886339 R 331111 CDS YP_001462976.1 157159125 5590022 complement(1887585..1888331) 1 NC_009801.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase 1888331 sufC 5590022 sufC Escherichia coli E24377A cysteine desulfurase YP_001462976.1 1887585 R 331111 CDS YP_001462977.1 157156777 5586811 complement(1888341..1889828) 1 NC_009801.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 1889828 sufB 5586811 sufB Escherichia coli E24377A cysteine desulfurase activator complex subunit SufB YP_001462977.1 1888341 R 331111 CDS YP_001462978.1 157156081 5589141 complement(1889837..1890205) 1 NC_009801.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein 1890205 sufA 5589141 sufA Escherichia coli E24377A iron-sulfur cluster assembly scaffold protein YP_001462978.1 1889837 R 331111 CDS YP_001462979.1 157157511 5589849 complement(1890754..1891023) 1 NC_009801.1 identified by similarity to SP:P64478; hypothetical protein 1891023 5589849 EcE24377A_1901 Escherichia coli E24377A hypothetical protein YP_001462979.1 1890754 R 331111 CDS YP_001462980.1 157156892 5589685 complement(1891042..1891452) 1 NC_009801.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 1891452 ydiL 5589685 ydiL Escherichia coli E24377A hypothetical protein YP_001462980.1 1891042 R 331111 CDS YP_001462981.1 157158246 5585985 complement(1891449..1894505) 1 NC_009801.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; oxidoreductase, FAD-binding 1894505 5585985 EcE24377A_1903 Escherichia coli E24377A oxidoreductase, FAD-binding YP_001462981.1 1891449 R 331111 CDS YP_001462982.1 157157163 5586419 1894894..1896006 1 NC_009801.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; inner membrane protein 1896006 ydiK 5586419 ydiK Escherichia coli E24377A inner membrane protein YP_001462982.1 1894894 D 331111 CDS YP_001462983.1 157159427 5588153 1896408..1896791 1 NC_009801.1 identified by similarity to GB:ABB61800.1; match to protein family HMM PF08965; hypothetical protein 1896791 5588153 EcE24377A_1905 Escherichia coli E24377A hypothetical protein YP_001462983.1 1896408 D 331111 CDS YP_001462984.1 157158719 5588483 1896891..1898105 1 NC_009801.1 identified by match to protein family HMM PF07690; major facilitator family transporter 1898105 ydiM 5588483 ydiM Escherichia coli E24377A major facilitator family transporter YP_001462984.1 1896891 D 331111 CDS YP_001462985.1 157157413 5588675 1898326..1899597 1 NC_009801.1 identified by match to protein family HMM PF07690; major facilitator transporter 1899597 5588675 EcE24377A_1907 Escherichia coli E24377A major facilitator transporter YP_001462985.1 1898326 D 331111 CDS YP_001462986.1 157159422 5589016 1899609..1900475 1 NC_009801.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 1900475 5589016 EcE24377A_1908 Escherichia coli E24377A quinate/shikimate dehydrogenase YP_001462986.1 1899609 D 331111 CDS YP_001462987.1 157158795 5586131 1900506..1901264 1 NC_009801.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1901264 aroD 5586131 aroD Escherichia coli E24377A 3-dehydroquinate dehydratase YP_001462987.1 1900506 D 331111 CDS YP_001462988.1 157155387 5588146 1901408..1903003 1 NC_009801.1 identified by match to protein family HMM PF01144; CoA-transferase 1903003 5588146 EcE24377A_1910 Escherichia coli E24377A CoA-transferase YP_001462988.1 1901408 D 331111 CDS YP_001462989.1 157154739 5586949 1903017..1904168 1 NC_009801.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; acyl-CoA dehydrogenase 1904168 5586949 EcE24377A_1911 Escherichia coli E24377A acyl-CoA dehydrogenase YP_001462989.1 1903017 D 331111 CDS YP_001462990.1 157156762 5589073 complement(1904211..1905122) 1 NC_009801.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311; match to protein family HMM PF07883; AraC family transcriptional regulator 1905122 5589073 EcE24377A_1912 Escherichia coli E24377A AraC family transcriptional regulator YP_001462990.1 1904211 R 331111 CDS YP_001462991.1 157156111 5589699 complement(1905225..1905401) 1 NC_009801.1 identified by glimmer; hypothetical protein 1905401 5589699 EcE24377A_1913 Escherichia coli E24377A hypothetical protein YP_001462991.1 1905225 R 331111 CDS YP_001462992.1 157159343 5590770 1905438..1906202 1 NC_009801.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; electron transfer flavoprotein YdiQ 1906202 fixA 5590770 fixA Escherichia coli E24377A electron transfer flavoprotein YdiQ YP_001462992.1 1905438 D 331111 CDS YP_001462993.1 157157549 5587144 1906222..1907160 1 NC_009801.1 May play a role in a redox process; electron transfer flavoprotein subunit YdiR 1907160 5587144 EcE24377A_1915 Escherichia coli E24377A electron transfer flavoprotein subunit YdiR YP_001462993.1 1906222 D 331111 CDS YP_001462994.1 157154713 5586089 1907216..1908505 1 NC_009801.1 identified by similarity to SP:P68644; match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486; hypothetical protein 1908505 5586089 EcE24377A_1916 Escherichia coli E24377A hypothetical protein YP_001462994.1 1907216 D 331111 CDS YP_001462995.1 157155358 5590421 1908502..1908795 1 NC_009801.1 (Fe-S)-binding protein 1908795 5590421 EcE24377A_1917 Escherichia coli E24377A (Fe-S)-binding protein YP_001462995.1 1908502 D 331111 CDS YP_001462996.1 157156226 5589217 1908852..1910498 1 NC_009801.1 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 1910498 fadK 5589217 fadK Escherichia coli E24377A short chain acyl-CoA synthetase YP_001462996.1 1908852 D 331111 CDS YP_001462997.1 157156730 5586962 complement(1910555..1912933) 1 NC_009801.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 1912933 ppsA 5586962 ppsA Escherichia coli E24377A phosphoenolpyruvate synthase YP_001462997.1 1910555 R 331111 CDS YP_001462998.1 157157496 5586499 complement(1912987..1913154) 1 NC_009801.1 hypothetical protein 1913154 5586499 EcE24377A_1920 Escherichia coli E24377A hypothetical protein YP_001462998.1 1912987 R 331111 CDS YP_001462999.1 157158010 5588803 1913266..1914099 1 NC_009801.1 identified by similarity to SP:Q8ZDY4; match to protein family HMM PF03618; hypothetical protein 1914099 5588803 EcE24377A_1921 Escherichia coli E24377A hypothetical protein YP_001462999.1 1913266 D 331111 CDS YP_001463000.1 157157604 5589175 1914256..1915302 1 NC_009801.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1915302 aroH 5589175 aroH Escherichia coli E24377A phospho-2-dehydro-3-deoxyheptonate aldolase YP_001463000.1 1914256 D 331111 CDS YP_001463001.1 157158001 5586984 1915434..1915625 1 NC_009801.1 identified by similarity to GB:ABB66046.1; hypothetical protein 1915625 5586984 EcE24377A_1923 Escherichia coli E24377A hypothetical protein YP_001463001.1 1915434 D 331111 CDS YP_001463002.1 157156707 5586545 complement(1915629..1917065) 1 NC_009801.1 identified by similarity to SP:Q8Z6I8; match to protein family HMM PF02696; hypothetical protein 1917065 5586545 EcE24377A_1924 Escherichia coli E24377A hypothetical protein YP_001463002.1 1915629 R 331111 CDS YP_001463003.1 157155976 5589923 1916156..1916257 1 NC_009801.1 identified by glimmer; hypothetical protein 1916257 5589923 EcE24377A_1925 Escherichia coli E24377A hypothetical protein YP_001463003.1 1916156 D 331111 CDS YP_001463004.1 157154728 5587136 complement(1917128..1917841) 1 NC_009801.1 identified by similarity to GB:AAP17004.1; hypothetical protein 1917841 5587136 EcE24377A_1926 Escherichia coli E24377A hypothetical protein YP_001463004.1 1917128 R 331111 CDS YP_001463005.1 157159105 5588224 complement(1918088..1918552) 1 NC_009801.1 identified by match to protein family HMM PF00877; NlpC/P60 family lipoprotein 1918552 5588224 EcE24377A_1927 Escherichia coli E24377A NlpC/P60 family lipoprotein YP_001463005.1 1918088 R 331111 CDS YP_001463006.1 157156393 5590029 complement(1918630..1919379) 1 NC_009801.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 1919379 btuD 5590029 btuD Escherichia coli E24377A vitamin B12-transporter ATPase YP_001463006.1 1918630 R 331111 CDS YP_001463007.1 157155390 5590764 complement(1919379..1919930) 1 NC_009801.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase 1919930 btuE 5590764 btuE Escherichia coli E24377A glutathione peroxidase YP_001463007.1 1919379 R 331111 CDS YP_001463008.1 157158270 5588734 complement(1919993..1920973) 1 NC_009801.1 with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 1920973 btuC 5588734 btuC Escherichia coli E24377A vtamin B12-transporter permease YP_001463008.1 1919993 R 331111 CDS YP_001463009.1 157159273 5588033 complement(1921074..1921373) 1 NC_009801.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1921373 ihfA 5588033 ihfA Escherichia coli E24377A integration host factor subunit alpha YP_001463009.1 1921074 R 331111 CDS YP_001463010.1 157158594 5586092 complement(1921378..1923765) 1 NC_009801.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1923765 pheT 5586092 pheT Escherichia coli E24377A phenylalanyl-tRNA synthetase subunit beta YP_001463010.1 1921378 R 331111 CDS YP_001463011.1 157158955 5589852 complement(1923780..1924763) 1 NC_009801.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1924763 pheS 5589852 pheS Escherichia coli E24377A phenylalanyl-tRNA synthetase subunit alpha YP_001463011.1 1923780 R 331111 CDS YP_001463012.1 157154737 5586461 complement(1924877..1924972) 1 NC_009801.1 identified by glimmer; hypothetical protein 1924972 5586461 EcE24377A_1934 Escherichia coli E24377A hypothetical protein YP_001463012.1 1924877 R 331111 CDS YP_001463013.1 157155376 5588837 complement(1925214..1925570) 1 NC_009801.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1925570 rplT 5588837 rplT Escherichia coli E24377A 50S ribosomal protein L20 YP_001463013.1 1925214 R 331111 CDS YP_001463014.1 157156228 5589654 complement(1925917..1926351) 1 NC_009801.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1926351 infC 5589654 infC Escherichia coli E24377A translation initiation factor IF-3 YP_001463014.1 1925917 R 331111 CDS YP_001463015.1 157158126 5586882 complement(1926463..1928391) 1 NC_009801.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 1928391 thrS 5586882 thrS Escherichia coli E24377A threonyl-tRNA synthetase YP_001463015.1 1926463 R 331111 CDS YP_001463016.1 157157478 5590653 complement(1930808..1930918) 1 NC_009801.1 identified by glimmer; hypothetical protein 1930918 5590653 EcE24377A_1939 Escherichia coli E24377A hypothetical protein YP_001463016.1 1930808 R 331111 CDS YP_001463017.1 157158105 5587580 complement(1931149..1931907) 1 NC_009801.1 identified by match to protein family HMM PF04338; hypothetical protein 1931907 5587580 EcE24377A_1941 Escherichia coli E24377A hypothetical protein YP_001463017.1 1931149 R 331111 CDS YP_001463018.1 157159076 5587620 1932048..1932155 1 NC_009801.1 identified by glimmer; hypothetical protein 1932155 5587620 EcE24377A_1942 Escherichia coli E24377A hypothetical protein YP_001463018.1 1932048 D 331111 CDS YP_001463019.1 157159329 5586853 1932194..1933123 1 NC_009801.1 identified by similarity to SP:P06999; match to protein family HMM PF00294; match to protein family HMM TIGR03168; 6-phosphofructokinase 1933123 pfkB 5586853 pfkB Escherichia coli E24377A 6-phosphofructokinase YP_001463019.1 1932194 D 331111 CDS YP_001463020.1 157158813 5589101 1933224..1933514 1 NC_009801.1 identified by similarity to SP:P64479; hypothetical protein 1933514 5589101 EcE24377A_1944 Escherichia coli E24377A hypothetical protein YP_001463020.1 1933224 D 331111 CDS YP_001463021.1 157155902 5587729 1933620..1934480 1 NC_009801.1 identified by match to protein family HMM PF01636; match to protein family HMM PF03881; fructosamine kinase 1934480 5587729 EcE24377A_1945 Escherichia coli E24377A fructosamine kinase YP_001463021.1 1933620 D 331111 CDS YP_001463022.1 157155190 5586640 complement(1934521..1935057) 1 NC_009801.1 identified by similarity to GB:AAZ88138.1; hypothetical protein 1935057 5586640 EcE24377A_1946 Escherichia coli E24377A hypothetical protein YP_001463022.1 1934521 R 331111 CDS YP_001463023.1 157156625 5588652 1935204..1935872 1 NC_009801.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1935872 5588652 EcE24377A_1947 Escherichia coli E24377A 2-deoxyglucose-6-phosphatase YP_001463023.1 1935204 D 331111 CDS YP_001463024.1 157157851 5586305 1936035..1936625 1 NC_009801.1 identified by match to protein family HMM PF04307; hypothetical protein 1936625 5586305 EcE24377A_1949 Escherichia coli E24377A hypothetical protein YP_001463024.1 1936035 D 331111 CDS YP_001463025.1 157156187 5589390 complement(1936557..1936685) 1 NC_009801.1 identified by glimmer; hypothetical protein 1936685 5589390 EcE24377A_1948 Escherichia coli E24377A hypothetical protein YP_001463025.1 1936557 R 331111 CDS YP_001463026.1 157158064 5588679 1936758..1938149 1 NC_009801.1 identified by match to protein family HMM PF00375; sodium/dicarboxylate symporter family protein 1938149 5588679 EcE24377A_1950 Escherichia coli E24377A sodium/dicarboxylate symporter family protein YP_001463026.1 1936758 D 331111 CDS YP_001463027.1 157155560 5588112 complement(1939245..1939487) 1 NC_009801.1 identified by similarity to SP:P0AE60; cell division modulator 1939487 cedA 5588112 cedA Escherichia coli E24377A cell division modulator YP_001463027.1 1939245 R 331111 CDS YP_001463028.1 157154864 5589054 1939691..1941952 1 NC_009801.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1941952 katE 5589054 katE Escherichia coli E24377A hydroperoxidase II YP_001463028.1 1939691 D 331111 CDS YP_001463029.1 157156630 5590842 complement(1941999..1942757) 1 NC_009801.1 identified by similarity to GB:BAB92994.1; match to protein family HMM PF04794; hypothetical protein 1942757 5590842 EcE24377A_1954 Escherichia coli E24377A hypothetical protein YP_001463029.1 1941999 R 331111 CDS YP_001463030.1 157156065 5587016 complement(1942770..1944122) 1 NC_009801.1 identified by similarity to SP:P17411; match to protein family HMM PF02056; 6-phospho-beta-glucosidase 1944122 chbF 5587016 chbF Escherichia coli E24377A 6-phospho-beta-glucosidase YP_001463030.1 1942770 R 331111 CDS YP_001463031.1 157158276 5590132 complement(1944227..1945066) 1 NC_009801.1 represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR 1945066 chbR 5590132 chbR Escherichia coli E24377A DNA-binding transcriptional regulator ChbR YP_001463031.1 1944227 R 331111 CDS YP_001463032.1 157157611 5588727 complement(1945077..1945427) 1 NC_009801.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 1945427 chbA 5588727 chbA Escherichia coli E24377A PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA YP_001463032.1 1945077 R 331111 CDS YP_001463033.1 157159318 5590299 complement(1945478..1946836) 1 NC_009801.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 1946836 chbC 5590299 chbC Escherichia coli E24377A PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC YP_001463033.1 1945478 R 331111 CDS YP_001463034.1 157158685 5588927 complement(1946921..1947241) 1 NC_009801.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 1947241 chbB 5588927 chbB Escherichia coli E24377A PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB YP_001463034.1 1946921 R 331111 CDS YP_001463035.1 157158256 5590313 complement(1947540..1947878) 1 NC_009801.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE 1947878 osmE 5590313 osmE Escherichia coli E24377A DNA-binding transcriptional activator OsmE YP_001463035.1 1947540 R 331111 CDS YP_001463036.1 157157598 5586821 1948080..1948907 1 NC_009801.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1948907 nadE 5586821 nadE Escherichia coli E24377A NAD synthetase YP_001463036.1 1948080 D 331111 CDS YP_001463037.1 157156765 5590367 1949137..1950024 1 NC_009801.1 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1950024 cho 5590367 cho Escherichia coli E24377A nucleotide excision repair endonuclease YP_001463037.1 1949137 D 331111 CDS YP_001463038.1 157156839 5589663 complement(1949984..1950559) 1 NC_009801.1 identified by match to protein family HMM PF05962; hypothetical protein 1950559 5589663 EcE24377A_1962 Escherichia coli E24377A hypothetical protein YP_001463038.1 1949984 R 331111 CDS YP_001463039.1 157158229 5590728 complement(1950762..1951247) 1 NC_009801.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein 1951247 spy 5590728 spy Escherichia coli E24377A hypothetical protein YP_001463039.1 1950762 R 331111 CDS YP_001463040.1 157158937 5587799 1951382..1951483 1 NC_009801.1 identified by glimmer; hypothetical protein 1951483 5587799 EcE24377A_1965 Escherichia coli E24377A hypothetical protein YP_001463040.1 1951382 D 331111 CDS YP_001463041.1 157155284 5586813 complement(1951577..1952545) 1 NC_009801.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 1952545 astE 5586813 astE Escherichia coli E24377A succinylglutamate desuccinylase YP_001463041.1 1951577 R 331111 CDS YP_001463042.1 157155531 5585946 complement(1952538..1953881) 1 NC_009801.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 1953881 astB 5585946 astB Escherichia coli E24377A succinylarginine dihydrolase YP_001463042.1 1952538 R 331111 CDS YP_001463043.1 157156088 5586005 complement(1953878..1955356) 1 NC_009801.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 1955356 astD 5586005 astD Escherichia coli E24377A succinylglutamic semialdehyde dehydrogenase YP_001463043.1 1953878 R 331111 CDS YP_001463044.1 157157503 5587085 complement(1955353..1956387) 1 NC_009801.1 identified by match to protein family HMM PF04958; match to protein family HMM TIGR03244; arginine succinyltransferase 1956387 astA 5587085 astA Escherichia coli E24377A arginine succinyltransferase YP_001463044.1 1955353 R 331111 CDS YP_001463045.1 157158020 5588995 complement(1956384..1957604) 1 NC_009801.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase 1957604 astC 5588995 astC Escherichia coli E24377A bifunctional succinylornithine transaminase/acetylornithine transaminase YP_001463045.1 1956384 R 331111 CDS YP_001463046.1 157157197 5588979 1957867..1958037 1 NC_009801.1 identified by glimmer; hypothetical protein 1958037 5588979 EcE24377A_1971 Escherichia coli E24377A hypothetical protein YP_001463046.1 1957867 D 331111 CDS YP_001463047.1 157157800 5586922 1958050..1958856 1 NC_009801.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1958856 xth 5586922 xth Escherichia coli E24377A exonuclease III YP_001463047.1 1958050 D 331111 CDS YP_001463048.1 157156391 5589623 1959023..1959733 1 NC_009801.1 identified by match to protein family HMM PF09335; hypothetical protein 1959733 5589623 EcE24377A_1973 Escherichia coli E24377A hypothetical protein YP_001463048.1 1959023 D 331111 CDS YP_001463049.1 157157066 5586059 1959576..1960415 1 NC_009801.1 identified by similarity to GB:AAZ88114.1; hypothetical protein 1960415 5586059 EcE24377A_1974 Escherichia coli E24377A hypothetical protein YP_001463049.1 1959576 D 331111 CDS YP_001463050.1 157156819 5588360 1960430..1961137 1 NC_009801.1 identified by similarity to SP:P76221; match to protein family HMM PF09335; hypothetical protein 1961137 5588360 EcE24377A_1975 Escherichia coli E24377A hypothetical protein YP_001463050.1 1960430 D 331111 CDS YP_001463051.1 157155699 5586582 1961137..1961685 1 NC_009801.1 identified by match to protein family HMM PF02627; carboxymuconolactone decarboxylase 1961685 5586582 EcE24377A_1976 Escherichia coli E24377A carboxymuconolactone decarboxylase YP_001463051.1 1961137 D 331111 CDS YP_001463052.1 157155445 5587655 1961695..1962861 1 NC_009801.1 ABC transporter substrate-binding protein 1962861 5587655 EcE24377A_1977 Escherichia coli E24377A ABC transporter substrate-binding protein YP_001463052.1 1961695 D 331111 CDS YP_001463053.1 157158532 5589887 1962834..1964369 1 NC_009801.1 ABC transporter permease 1964369 ynjC 5589887 ynjC Escherichia coli E24377A ABC transporter permease YP_001463053.1 1962834 D 331111 CDS YP_001463054.1 157158900 5590418 1964369..1965022 1 NC_009801.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1965022 5590418 EcE24377A_1979 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001463054.1 1964369 D 331111 CDS YP_001463055.1 157157667 5586403 1965089..1966396 1 NC_009801.1 rhodanese-like domain-containing protein 1966396 5586403 EcE24377A_1980 Escherichia coli E24377A rhodanese-like domain-containing protein YP_001463055.1 1965089 D 331111 CDS YP_001463056.1 157156475 5588262 complement(1966405..1967025) 1 NC_009801.1 identified by match to protein family HMM PF01066; CDP-alcohol phosphatidyltransferase 1967025 5588262 EcE24377A_1981 Escherichia coli E24377A CDP-alcohol phosphatidyltransferase YP_001463056.1 1966405 R 331111 CDS YP_001463057.1 157157514 5589936 1967112..1967519 1 NC_009801.1 identified by similarity to SP:P77788; match to protein family HMM PF00293; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1967519 nudG 5589936 nudG Escherichia coli E24377A pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase YP_001463057.1 1967112 D 331111 CDS YP_001463058.1 157157965 5588961 complement(1967485..1967757) 1 NC_009801.1 identified by match to protein family HMM PF07383; hypothetical protein 1967757 5588961 EcE24377A_1982 Escherichia coli E24377A hypothetical protein YP_001463058.1 1967485 R 331111 CDS YP_001463059.1 157158996 5589791 1967993..1969336 1 NC_009801.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1969336 gdhA 5589791 gdhA Escherichia coli E24377A glutamate dehydrogenase YP_001463059.1 1967993 D 331111 CDS YP_001463060.1 157158320 5588043 complement(1969453..1970493) 1 NC_009801.1 identified by similarity to GB:AAN43058.1; hypothetical protein 1970493 5588043 EcE24377A_1985 Escherichia coli E24377A hypothetical protein YP_001463060.1 1969453 R 331111 CDS YP_001463061.1 157157904 5587755 complement(1970621..1972582) 1 NC_009801.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 1972582 topB 5587755 topB Escherichia coli E24377A DNA topoisomerase III YP_001463061.1 1970621 R 331111 CDS YP_001463062.1 157157367 5590441 complement(1972587..1973630) 1 NC_009801.1 catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 1973630 selD 5590441 selD Escherichia coli E24377A selenophosphate synthetase YP_001463062.1 1972587 R 331111 CDS YP_001463063.1 157158892 5587471 complement(1973747..1974298) 1 NC_009801.1 identified by match to protein family HMM PF00881; hypothetical protein 1974298 5587471 EcE24377A_1988 Escherichia coli E24377A hypothetical protein YP_001463063.1 1973747 R 331111 CDS YP_001463064.1 157158383 5586946 1974352..1974516 1 NC_009801.1 identified by glimmer; hypothetical protein 1974516 5586946 EcE24377A_1989 Escherichia coli E24377A hypothetical protein YP_001463064.1 1974352 D 331111 CDS YP_001463065.1 157158760 5587437 1974459..1976315 1 NC_009801.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 1976315 sppA 5587437 sppA Escherichia coli E24377A protease 4 YP_001463065.1 1974459 D 331111 CDS YP_001463066.1 157158977 5590799 1976482..1977498 1 NC_009801.1 converts asparagine to aspartate and ammonia; asparaginase 1977498 ansA 5590799 ansA Escherichia coli E24377A asparaginase YP_001463066.1 1976482 D 331111 CDS YP_001463067.1 157155759 5587829 1977509..1978150 1 NC_009801.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 1978150 pncA 5587829 pncA Escherichia coli E24377A nicotinamidase/pyrazinamidase YP_001463067.1 1977509 D 331111 CDS YP_001463068.1 157155243 5588309 complement(1978243..1979601) 1 NC_009801.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator family transporter 1979601 ydjE 5588309 ydjE Escherichia coli E24377A major facilitator family transporter YP_001463068.1 1978243 R 331111 CDS YP_001463069.1 157158664 5587156 complement(1979718..1980476) 1 NC_009801.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; DeoR family transcriptional regulator 1980476 5587156 EcE24377A_1994 Escherichia coli E24377A DeoR family transcriptional regulator YP_001463069.1 1979718 R 331111 CDS YP_001463070.1 157159254 5587350 complement(1980613..1981593) 1 NC_009801.1 identified by match to protein family HMM PF00248; aldo/keto reductase 1981593 5587350 EcE24377A_1995 Escherichia coli E24377A aldo/keto reductase YP_001463070.1 1980613 R 331111 CDS YP_001463071.1 157159112 5590017 complement(1981603..1982550) 1 NC_009801.1 identified by match to protein family HMM PF00294; PfkB family kinase 1982550 5590017 EcE24377A_1996 Escherichia coli E24377A PfkB family kinase YP_001463071.1 1981603 R 331111 CDS YP_001463072.1 157154881 5588739 complement(1982555..1983391) 1 NC_009801.1 identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; fructose-bisphosphate aldolase 1983391 5588739 EcE24377A_1997 Escherichia coli E24377A fructose-bisphosphate aldolase YP_001463072.1 1982555 R 331111 CDS YP_001463073.1 157155393 5589857 complement(1983412..1984455) 1 NC_009801.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; sorbitol dehydrogenase 1984455 gutB 5589857 gutB Escherichia coli E24377A sorbitol dehydrogenase YP_001463073.1 1983412 R 331111 CDS YP_001463074.1 157155942 5589831 complement(1984472..1985851) 1 NC_009801.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator family transporter 1985851 ydjK 5589831 ydjK Escherichia coli E24377A major facilitator family transporter YP_001463074.1 1984472 R 331111 CDS YP_001463075.1 157156926 5588709 complement(1985878..1986954) 1 NC_009801.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; zinc-binding dehydrogenase oxidoreductase 1986954 5588709 EcE24377A_2000 Escherichia coli E24377A zinc-binding dehydrogenase oxidoreductase YP_001463075.1 1985878 R 331111 CDS YP_001463076.1 157158076 5587234 complement(1987324..1987596) 1 NC_009801.1 identified by match to protein family HMM PF07023; hypothetical protein 1987596 5587234 EcE24377A_2001 Escherichia coli E24377A hypothetical protein YP_001463076.1 1987324 R 331111 CDS YP_001463077.1 157156280 5588805 complement(1987638..1988051) 1 NC_009801.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 1988051 msrB 5588805 msrB Escherichia coli E24377A methionine sulfoxide reductase B YP_001463077.1 1987638 R 331111 CDS YP_001463078.1 157156808 5590753 1988393..1989388 1 NC_009801.1 identified by similarity to SP:P0A9B2; match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; giyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 1989388 gapA 5590753 gapA Escherichia coli E24377A giyceraldehyde-3-phosphate dehydrogenase (phosphorylating) YP_001463078.1 1988393 D 331111 CDS YP_001463079.1 157154792 5587484 1989451..1990356 1 NC_009801.1 identified by match to protein family HMM PF01263; aldose 1-epimerase 1990356 5587484 EcE24377A_2004 Escherichia coli E24377A aldose 1-epimerase YP_001463079.1 1989451 D 331111 CDS YP_001463080.1 157155366 5588348 complement(1990407..1991261) 1 NC_009801.1 identified by match to protein family HMM PF00248; aldo/keto reductase 1991261 5588348 EcE24377A_2005 Escherichia coli E24377A aldo/keto reductase YP_001463080.1 1990407 R 331111 CDS YP_001463081.1 157156122 5589792 complement(1991351..1992097) 1 NC_009801.1 identified by similarity to SP:P0A908; match to protein family HMM PF06629; MltA-interacting protein MipA 1992097 mipA 5589792 mipA Escherichia coli E24377A MltA-interacting protein MipA YP_001463081.1 1991351 R 331111 CDS YP_001463082.1 157156559 5587613 1992533..1994467 1 NC_009801.1 identified by match to protein family HMM PF06798; match to protein family HMM PF08298; serine kinase 1994467 5587613 EcE24377A_2007 Escherichia coli E24377A serine kinase YP_001463082.1 1992533 D 331111 CDS YP_001463083.1 157154798 5588871 1994580..1995863 1 NC_009801.1 identified by match to protein family HMM PF04285; hypothetical protein 1995863 5588871 EcE24377A_2008 Escherichia coli E24377A hypothetical protein YP_001463083.1 1994580 D 331111 CDS YP_001463084.1 157155175 5588197 1996010..1997485 1 NC_009801.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 1997485 5588197 EcE24377A_2009 Escherichia coli E24377A diguanylate cyclase YP_001463084.1 1996010 D 331111 CDS YP_001463085.1 157158224 5588264 1997666..1999156 1 NC_009801.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 1999156 5588264 EcE24377A_2010 Escherichia coli E24377A diguanylate cyclase YP_001463085.1 1997666 D 331111 CDS YP_001463086.1 157157881 5589973 1999199..1999702 1 NC_009801.1 identified by match to protein family HMM PF04073; prolyl-tRNA synthetase 1999702 5589973 EcE24377A_2011 Escherichia coli E24377A prolyl-tRNA synthetase YP_001463086.1 1999199 D 331111 CDS YP_001463087.1 157158404 5588819 complement(1999703..1999855) 1 NC_009801.1 identified by similarity to GB:AAZ88084.1; hypothetical protein 1999855 5588819 EcE24377A_2012 Escherichia coli E24377A hypothetical protein YP_001463087.1 1999703 R 331111 CDS YP_001463088.1 157158941 5588703 1999977..2000423 1 NC_009801.1 identified by similarity to SP:P0ACY8; match to protein family HMM PF04284; hypothetical protein 2000423 5588703 EcE24377A_2014 Escherichia coli E24377A hypothetical protein YP_001463088.1 1999977 D 331111 CDS YP_001463089.1 157155818 5589672 2001298..2002479 1 NC_009801.1 identified by similarity to SP:P76242; match to protein family HMM PF07690; match to protein family HMM TIGR00896; inner membrane transport protein yeaN 2002479 yeaN 5589672 yeaN Escherichia coli E24377A inner membrane transport protein yeaN YP_001463089.1 2001298 D 331111 CDS YP_001463090.1 157156357 5586114 2002534..2002881 1 NC_009801.1 identified by match to protein family HMM PF04343; hypothetical protein 2002881 5586114 EcE24377A_2016 Escherichia coli E24377A hypothetical protein YP_001463090.1 2002534 D 331111 CDS YP_001463091.1 157156904 5590645 complement(2002903..2003157) 1 NC_009801.1 identified by match to protein family HMM PF03891; lipoprotein 2003157 5590645 EcE24377A_2017 Escherichia coli E24377A lipoprotein YP_001463091.1 2002903 R 331111 CDS YP_001463092.1 157157378 5586438 2003211..2004365 1 NC_009801.1 identified by match to protein family HMM PF00990; match to protein family HMM PF01590; match to protein family HMM TIGR00254; GAF domain/diguanylate cyclase domain-containing protein 2004365 5586438 EcE24377A_2018 Escherichia coli E24377A GAF domain/diguanylate cyclase domain-containing protein YP_001463092.1 2003211 D 331111 CDS YP_001463093.1 157157906 5586848 2004383..2004496 1 NC_009801.1 identified by glimmer; hypothetical protein 2004496 5586848 EcE24377A_2019 Escherichia coli E24377A hypothetical protein YP_001463093.1 2004383 D 331111 CDS YP_001463094.1 157158378 5588023 complement(2004632..2004880) 1 NC_009801.1 identified by match to protein family HMM PF04226; hypothetical protein 2004880 5588023 EcE24377A_2020 Escherichia coli E24377A hypothetical protein YP_001463094.1 2004632 R 331111 CDS YP_001463095.1 157155979 5587609 complement(2004892..2005047) 1 NC_009801.1 identified by glimmer; hypothetical protein 2005047 5587609 EcE24377A_2021 Escherichia coli E24377A hypothetical protein YP_001463095.1 2004892 R 331111 CDS YP_001463096.1 157156692 5588636 complement(2005107..2006315) 1 NC_009801.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766; IS605 family transposase OrfB 2006315 5588636 EcE24377A_2022 Escherichia coli E24377A IS605 family transposase OrfB YP_001463096.1 2005107 R 331111 CDS YP_001463097.1 157158023 5587940 2006338..2007285 1 NC_009801.1 identified by match to protein family HMM PF01797; IS605 family transposase 2007285 5587940 EcE24377A_2023 Escherichia coli E24377A IS605 family transposase YP_001463097.1 2006338 D 331111 CDS YP_001463098.1 157155360 5586736 complement(2007494..2008132) 1 NC_009801.1 identified by match to protein family HMM PF01810; leucine export protein LeuE 2008132 5586736 EcE24377A_2024 Escherichia coli E24377A leucine export protein LeuE YP_001463098.1 2007494 R 331111 CDS YP_001463099.1 157159337 5589869 complement(2008259..2009182) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2009182 5589869 EcE24377A_2025 Escherichia coli E24377A LysR family transcriptional regulator YP_001463099.1 2008259 R 331111 CDS YP_001463100.1 157156732 5590704 2009285..2010370 1 NC_009801.1 identified by similarity to SP:Q51945; match to protein family HMM PF00180; match to protein family HMM TIGR02089; tartrate dehydrogenase/decarboxylase 2010370 ttuC 5590704 ttuC Escherichia coli E24377A tartrate dehydrogenase/decarboxylase YP_001463100.1 2009285 D 331111 CDS YP_001463101.1 157154828 5586358 2010621..2012231 1 NC_009801.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function; transporter 2012231 5586358 EcE24377A_2027 Escherichia coli E24377A transporter YP_001463101.1 2010621 D 331111 CDS YP_001463102.1 157154831 5586618 2012263..2013387 1 NC_009801.1 identified by match to protein family HMM PF00355; Rieske (2Fe-2S) domain-containing protein 2013387 5586618 EcE24377A_2028 Escherichia coli E24377A Rieske (2Fe-2S) domain-containing protein YP_001463102.1 2012263 D 331111 CDS YP_001463103.1 157155807 5586510 2013443..2014408 1 NC_009801.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; oxidoreductase, FAD/NAD-binding/iron-sulfur cluster binding protein 2014408 5586510 EcE24377A_2029 Escherichia coli E24377A oxidoreductase, FAD/NAD-binding/iron-sulfur cluster binding protein YP_001463103.1 2013443 D 331111 CDS YP_001463104.1 157156075 5588539 complement(2014462..2015589) 1 NC_009801.1 identified by match to protein family HMM PF00570; match to protein family HMM PF01612; match to protein family HMM TIGR01388; ribonuclease D 2015589 rnd 5588539 rnd Escherichia coli E24377A ribonuclease D YP_001463104.1 2014462 R 331111 CDS YP_001463105.1 157156786 5588458 complement(2015659..2017344) 1 NC_009801.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 2017344 fadD 5588458 fadD Escherichia coli E24377A long-chain-fatty-acid--CoA ligase YP_001463105.1 2015659 R 331111 CDS YP_001463106.1 157156195 5588656 complement(2017549..2018130) 1 NC_009801.1 identified by similarity to SP:P37194; match to protein family HMM PF03843; match to protein family HMM TIGR00752; outer membrane protein Slp 2018130 slp 5588656 slp Escherichia coli E24377A outer membrane protein Slp YP_001463106.1 2017549 R 331111 CDS YP_001463107.1 157156729 5588556 complement(2018170..2018865) 1 NC_009801.1 identified by match to protein family HMM PF00814; glycoprotease 2018865 5588556 EcE24377A_2033 Escherichia coli E24377A glycoprotease YP_001463107.1 2018170 R 331111 CDS YP_001463108.1 157157287 5586498 complement(2018923..2020833) 1 NC_009801.1 hypothetical protein 2020833 5586498 EcE24377A_2034 Escherichia coli E24377A hypothetical protein YP_001463108.1 2018923 R 331111 CDS YP_001463109.1 157157938 5586297 complement(2020866..2021252) 1 NC_009801.1 identified by glimmer; hypothetical protein 2021252 5586297 EcE24377A_2035 Escherichia coli E24377A hypothetical protein YP_001463109.1 2020866 R 331111 CDS YP_001463110.1 157155431 5590587 2020965..2021309 1 NC_009801.1 identified by match to protein family HMM PF01042; endoribonuclease L-PSP 2021309 5590587 EcE24377A_2036 Escherichia coli E24377A endoribonuclease L-PSP YP_001463110.1 2020965 D 331111 CDS YP_001463111.1 157158475 5590284 complement(2021343..2021480) 1 NC_009801.1 identified by glimmer; hypothetical protein 2021480 5590284 EcE24377A_2037 Escherichia coli E24377A hypothetical protein YP_001463111.1 2021343 R 331111 CDS YP_001463112.1 157157599 5585921 2021671..2022030 1 NC_009801.1 identified by similarity to SP:P64492; match to protein family HMM PF08986; hypothetical protein 2022030 5585921 EcE24377A_2038 Escherichia coli E24377A hypothetical protein YP_001463112.1 2021671 D 331111 CDS YP_001463113.1 157157253 5590368 complement(2022150..2022329) 1 NC_009801.1 identified by similarity to SP:P67338; match to protein family HMM PF03701; hypothetical protein 2022329 5590368 EcE24377A_2039 Escherichia coli E24377A hypothetical protein YP_001463113.1 2022150 R 331111 CDS YP_001463114.1 157158150 5588725 2022403..2023764 1 NC_009801.1 identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553; para-aminobenzoate synthase component I 2023764 pabB 5588725 pabB Escherichia coli E24377A para-aminobenzoate synthase component I YP_001463114.1 2022403 D 331111 CDS YP_001463115.1 157156711 5587509 2023768..2024346 1 NC_009801.1 identified by match to protein family HMM PF00293; hypothetical protein 2024346 5587509 EcE24377A_2041 Escherichia coli E24377A hypothetical protein YP_001463115.1 2023768 D 331111 CDS YP_001463116.1 157156174 5589468 2024530..2025894 1 NC_009801.1 identified by similarity to SP:P16095; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; L-serine dehydratase 1 2025894 sdaA 5589468 sdaA Escherichia coli E24377A L-serine dehydratase 1 YP_001463116.1 2024530 D 331111 CDS YP_001463117.1 157157134 5586573 complement(2027626..2029182) 1 NC_009801.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741; TerC family/CBS/transporter associated domain-containing protein 2029182 5586573 EcE24377A_2044 Escherichia coli E24377A TerC family/CBS/transporter associated domain-containing protein YP_001463117.1 2027626 R 331111 CDS YP_001463118.1 157158859 5589279 2029645..2030616 1 NC_009801.1 identified by match to protein family HMM PF03610; match to protein family HMM PF03830; match to protein family HMM TIGR00824; match to protein family HMM TIGR00854; PTS system mannose-specific transporter subunit IIAB 2030616 manX 5589279 manX Escherichia coli E24377A PTS system mannose-specific transporter subunit IIAB YP_001463118.1 2029645 D 331111 CDS YP_001463119.1 157155886 5587087 2030679..2031479 1 NC_009801.1 identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822; PTS system mannose-specific transporter subunit IIC 2031479 manY 5587087 manY Escherichia coli E24377A PTS system mannose-specific transporter subunit IIC YP_001463119.1 2030679 D 331111 CDS YP_001463120.1 157158926 5588601 2031492..2032343 1 NC_009801.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 2032343 manZ 5588601 manZ Escherichia coli E24377A PTS system mannose-specific transporter subunit IID YP_001463120.1 2031492 D 331111 CDS YP_001463121.1 157158437 5586052 2032398..2032856 1 NC_009801.1 identified by similarity to SP:Q8ZP01; match to protein family HMM PF06173; hypothetical protein 2032856 5586052 EcE24377A_2048 Escherichia coli E24377A hypothetical protein YP_001463121.1 2032398 D 331111 CDS YP_001463122.1 157158392 5590308 2033286..2033852 1 NC_009801.1 membrane protein YebN; hypothetical protein 2033852 5590308 EcE24377A_2050 Escherichia coli E24377A hypothetical protein YP_001463122.1 2033286 D 331111 CDS YP_001463123.1 157157858 5589757 complement(2033849..2034658) 1 NC_009801.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase 2034658 rrmA 5589757 rrmA Escherichia coli E24377A 23S rRNA methyltransferase YP_001463123.1 2033849 R 331111 CDS YP_001463124.1 157157347 5589905 complement(2034824..2035033) 1 NC_009801.1 identified by similarity to SP:P0A9Y6; match to protein family HMM PF00313; cold shock-like protein CspC 2035033 cspC 5589905 cspC Escherichia coli E24377A cold shock-like protein CspC YP_001463124.1 2034824 R 331111 CDS YP_001463125.1 157156894 5589627 complement(2035046..2035189) 1 NC_009801.1 identified by similarity to SP:P64511; hypothetical protein 2035189 5589627 EcE24377A_2052 Escherichia coli E24377A hypothetical protein YP_001463125.1 2035046 R 331111 CDS YP_001463126.1 157156232 5585987 complement(2035859..2036146) 1 NC_009801.1 identified by similarity to SP:P64499; hypothetical protein 2036146 5585987 EcE24377A_2053 Escherichia coli E24377A hypothetical protein YP_001463126.1 2035859 R 331111 CDS YP_001463127.1 157155554 5590304 complement(2036221..2036364) 1 NC_009801.1 hypothetical protein 2036364 5590304 EcE24377A_2054 Escherichia coli E24377A hypothetical protein YP_001463127.1 2036221 R 331111 CDS YP_001463128.1 157158695 5586181 2036523..2036762 1 NC_009801.1 identified by similarity to GB:ABB62074.1; hypothetical protein 2036762 5586181 EcE24377A_2055 Escherichia coli E24377A hypothetical protein YP_001463128.1 2036523 D 331111 CDS YP_001463129.1 157158080 5589019 complement(2036905..2037696) 1 NC_009801.1 identified by similarity to SP:P76268; match to protein family HMM PF01614; match to protein family HMM PF09339; transcriptional regulator KdgR 2037696 kdgR 5589019 kdgR Escherichia coli E24377A transcriptional regulator KdgR YP_001463129.1 2036905 R 331111 CDS YP_001463130.1 157156529 5589430 2037873..2039246 1 NC_009801.1 identified by match to protein family HMM PF07690; major facilitator transporter 2039246 5589430 EcE24377A_2057 Escherichia coli E24377A major facilitator transporter YP_001463130.1 2037873 D 331111 CDS YP_001463131.1 157156002 5587281 complement(2039292..2040173) 1 NC_009801.1 metalloprotease; heat shock protein HtpX 2040173 5587281 EcE24377A_2058 Escherichia coli E24377A heat shock protein HtpX YP_001463131.1 2039292 R 331111 CDS YP_001463132.1 157155122 5589847 complement(2040365..2042413) 1 NC_009801.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 2042413 prc 5589847 prc Escherichia coli E24377A carboxy-terminal protease YP_001463132.1 2040365 R 331111 CDS YP_001463133.1 157159080 5586643 complement(2042433..2043131) 1 NC_009801.1 affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector 2043131 proQ 5586643 proQ Escherichia coli E24377A solute/DNA competence effector YP_001463133.1 2042433 R 331111 CDS YP_001463134.1 157158805 5588884 complement(2043228..2043779) 1 NC_009801.1 identified by match to protein family HMM PF01590; GAF domain-containing protein 2043779 5588884 EcE24377A_2061 Escherichia coli E24377A GAF domain-containing protein YP_001463134.1 2043228 R 331111 CDS YP_001463135.1 157158026 5589245 2043855..2045138 1 NC_009801.1 identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155; PqiA family integral membrane protein 2045138 5589245 EcE24377A_2062 Escherichia coli E24377A PqiA family integral membrane protein YP_001463135.1 2043855 D 331111 CDS YP_001463136.1 157157260 5588760 2045101..2047740 1 NC_009801.1 identified by match to protein family HMM PF02470; mce-like protein 2047740 5588760 EcE24377A_2063 Escherichia coli E24377A mce-like protein YP_001463136.1 2045101 D 331111 CDS YP_001463137.1 157157684 5590679 2047814..2049259 1 NC_009801.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 2049259 yebU 5590679 yebU Escherichia coli E24377A rRNA (cytosine-C(5)-)-methyltransferase RsmF YP_001463137.1 2047814 D 331111 CDS YP_001463138.1 157159210 5587962 2049377..2049613 1 NC_009801.1 identified by match to protein family HMM PF07351; hypothetical protein 2049613 5587962 EcE24377A_2065 Escherichia coli E24377A hypothetical protein YP_001463138.1 2049377 D 331111 CDS YP_001463139.1 157159149 5588858 2049634..2049909 1 NC_009801.1 identified by match to protein family HMM PF07358; hypothetical protein 2049909 5588858 EcE24377A_2066 Escherichia coli E24377A hypothetical protein YP_001463139.1 2049634 D 331111 CDS YP_001463140.1 157158545 5589311 complement(2049910..2050566) 1 NC_009801.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 2050566 pphA 5589311 pphA Escherichia coli E24377A serine/threonine protein phosphatase 1 YP_001463140.1 2049910 R 331111 CDS YP_001463141.1 157157533 5587945 complement(2050962..2051303) 1 NC_009801.1 identified by similarity to GB:ABB61282.1; hypothetical protein 2051303 5587945 EcE24377A_2068 Escherichia coli E24377A hypothetical protein YP_001463141.1 2050962 R 331111 CDS YP_001463142.1 157156619 5588759 complement(2051316..2052188) 1 NC_009801.1 identified by match to protein family HMM PF05425; copper resistance protein D 2052188 5588759 EcE24377A_2069 Escherichia coli E24377A copper resistance protein D YP_001463142.1 2051316 R 331111 CDS YP_001463143.1 157155782 5590070 complement(2052192..2052566) 1 NC_009801.1 identified by match to protein family HMM PF04234; hypothetical protein 2052566 5590070 EcE24377A_2070 Escherichia coli E24377A hypothetical protein YP_001463143.1 2052192 R 331111 CDS YP_001463144.1 157155580 5588191 2052705..2052935 1 NC_009801.1 identified by similarity to SP:P0ABT1; match to protein family HMM PF06440; DNA polymerase III subunit theta 2052935 holE 5588191 holE Escherichia coli E24377A DNA polymerase III subunit theta YP_001463144.1 2052705 D 331111 CDS YP_001463145.1 157154761 5587307 2053037..2053693 1 NC_009801.1 identified by match to protein family HMM PF00795; carbon-nitrogen family hydrolase 2053693 5587307 EcE24377A_2072 Escherichia coli E24377A carbon-nitrogen family hydrolase YP_001463145.1 2053037 D 331111 CDS YP_001463146.1 157159299 5587912 2053717..2054379 1 NC_009801.1 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 2054379 exoX 5587912 exoX Escherichia coli E24377A exodeoxyribonuclease X YP_001463146.1 2053717 D 331111 CDS YP_001463147.1 157158505 5590483 complement(2054376..2056436) 1 NC_009801.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 2056436 prtB 5590483 prtB Escherichia coli E24377A protease 2 YP_001463147.1 2054376 R 331111 CDS YP_001463148.1 157158951 5589557 complement(2056645..2057304) 1 NC_009801.1 identified by match to protein family HMM PF04391; hypothetical protein 2057304 5589557 EcE24377A_2075 Escherichia coli E24377A hypothetical protein YP_001463148.1 2056645 R 331111 CDS YP_001463149.1 157154843 5587137 2057364..2057474 1 NC_009801.1 identified by glimmer; hypothetical protein 2057474 5587137 EcE24377A_2076 Escherichia coli E24377A hypothetical protein YP_001463149.1 2057364 D 331111 CDS YP_001463150.1 157156725 5590407 complement(2057631..2057987) 1 NC_009801.1 secreted protein; unknown function; hypothetical protein 2057987 5590407 EcE24377A_2077 Escherichia coli E24377A hypothetical protein YP_001463150.1 2057631 R 331111 CDS YP_001463151.1 157156185 5586245 complement(2058054..2058344) 1 NC_009801.1 identified by similarity to SP:P0ACY9; match to protein family HMM PF07130; DNA damage-inducible protein YebG 2058344 5586245 EcE24377A_2078 Escherichia coli E24377A DNA damage-inducible protein YebG YP_001463151.1 2058054 R 331111 CDS YP_001463152.1 157158666 5589121 2058478..2059656 1 NC_009801.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 2059656 purT 5589121 purT Escherichia coli E24377A phosphoribosylglycinamide formyltransferase 2 YP_001463152.1 2058478 D 331111 CDS YP_001463153.1 157159025 5587287 complement(2059712..2060353) 1 NC_009801.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 2060353 eda 5587287 eda Escherichia coli E24377A keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_001463153.1 2059712 R 331111 CDS YP_001463154.1 157157338 5588546 complement(2060390..2062201) 1 NC_009801.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 2062201 edd 5588546 edd Escherichia coli E24377A phosphogluconate dehydratase YP_001463154.1 2060390 R 331111 CDS YP_001463155.1 157157715 5590650 complement(2062436..2063911) 1 NC_009801.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2063911 zwf 5590650 zwf Escherichia coli E24377A glucose-6-phosphate 1-dehydrogenase YP_001463155.1 2062436 R 331111 CDS YP_001463156.1 157155435 5589146 2064249..2065118 1 NC_009801.1 Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 2065118 5589146 EcE24377A_2083 Escherichia coli E24377A DNA-binding transcriptional regulator HexR YP_001463156.1 2064249 D 331111 CDS YP_001463157.1 157155785 5590851 2065246..2066688 1 NC_009801.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2066688 pykA 5590851 pykA Escherichia coli E24377A pyruvate kinase YP_001463157.1 2065246 D 331111 CDS YP_001463158.1 157158075 5587695 complement(2066819..2067790) 1 NC_009801.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 2067790 msbB1 5587695 msbB1 Escherichia coli E24377A lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_001463158.1 2066819 R 331111 CDS YP_001463159.1 157157523 5589219 complement(2067910..2069232) 1 NC_009801.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551; match to protein family HMM PF04225; match to protein family HMM PF08525; hypothetical protein 2069232 5589219 EcE24377A_2086 Escherichia coli E24377A hypothetical protein YP_001463159.1 2067910 R 331111 CDS YP_001463160.1 157156162 5589876 complement(2069248..2070180) 1 NC_009801.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein 2070180 znuA 5589876 znuA Escherichia coli E24377A high-affinity zinc transporter periplasmic protein YP_001463160.1 2069248 R 331111 CDS YP_001463161.1 157157860 5590827 2070259..2071014 1 NC_009801.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 2071014 znuC 5590827 znuC Escherichia coli E24377A high-affinity zinc transporter ATPase YP_001463161.1 2070259 D 331111 CDS YP_001463162.1 157155379 5587722 2071011..2071796 1 NC_009801.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 2071796 znuB 5587722 znuB Escherichia coli E24377A high-affinity zinc transporter membrane protein YP_001463162.1 2071011 D 331111 CDS YP_001463163.1 157154884 5587409 complement(2071943..2072953) 1 NC_009801.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 2072953 ruvB 5587409 ruvB Escherichia coli E24377A Holliday junction DNA helicase RuvB YP_001463163.1 2071943 R 331111 CDS YP_001463164.1 157159402 5586077 complement(2072962..2073573) 1 NC_009801.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 2073573 ruvA 5586077 ruvA Escherichia coli E24377A Holliday junction DNA helicase RuvA YP_001463164.1 2072962 R 331111 CDS YP_001463165.1 157158285 5586526 2073731..2074450 1 NC_009801.1 identified by match to protein family HMM PF06520; hypothetical protein 2074450 5586526 EcE24377A_2092 Escherichia coli E24377A hypothetical protein YP_001463165.1 2073731 D 331111 CDS YP_001463166.1 157156383 5588650 complement(2074452..2074973) 1 NC_009801.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 2074973 ruvC 5588650 ruvC Escherichia coli E24377A Holliday junction resolvase YP_001463166.1 2074452 R 331111 CDS YP_001463167.1 157156937 5587093 complement(2075008..2075748) 1 NC_009801.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 2075748 5587093 EcE24377A_2094 Escherichia coli E24377A hypothetical protein YP_001463167.1 2075008 R 331111 CDS YP_001463168.1 157158883 5589439 complement(2075777..2076229) 1 NC_009801.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 2076229 ntpA 5589439 ntpA Escherichia coli E24377A dATP pyrophosphohydrolase YP_001463168.1 2075777 R 331111 CDS YP_001463169.1 157155835 5588589 complement(2076347..2078119) 1 NC_009801.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 2078119 aspS 5588589 aspS Escherichia coli E24377A aspartyl-tRNA synthetase YP_001463169.1 2076347 R 331111 CDS YP_001463170.1 157157865 5588414 complement(2078309..2078404) 1 NC_009801.1 identified by glimmer; hypothetical protein 2078404 5588414 EcE24377A_2097 Escherichia coli E24377A hypothetical protein YP_001463170.1 2078309 R 331111 CDS YP_001463171.1 157157368 5586097 2078429..2078995 1 NC_009801.1 identified by match to protein family HMM PF00857; hypothetical protein 2078995 5586097 EcE24377A_2098 Escherichia coli E24377A hypothetical protein YP_001463171.1 2078429 D 331111 CDS YP_001463172.1 157156908 5590509 2078992..2079810 1 NC_009801.1 identified by similarity to SP:P37348; match to protein family HMM PF01904; hypothetical protein 2079810 5590509 EcE24377A_2099 Escherichia coli E24377A hypothetical protein YP_001463172.1 2078992 D 331111 CDS YP_001463173.1 157156374 5587895 2079863..2080258 1 NC_009801.1 identified by similarity to SP:P64515; inner membrane protein 2080258 5587895 EcE24377A_2100 Escherichia coli E24377A inner membrane protein YP_001463173.1 2079863 D 331111 CDS YP_001463174.1 157158395 5589426 2080299..2081042 1 NC_009801.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00740; methyltransferase 2081042 5589426 EcE24377A_2101 Escherichia coli E24377A methyltransferase YP_001463174.1 2080299 D 331111 CDS YP_001463175.1 157155154 5587848 2081039..2082010 1 NC_009801.1 identified by match to protein family HMM PF08003; match to protein family HMM PF08241; match to protein family HMM TIGR00452; methyltransferase 2082010 5587848 EcE24377A_2102 Escherichia coli E24377A methyltransferase YP_001463175.1 2081039 D 331111 CDS YP_001463176.1 157157183 5590021 2082038..2082184 1 NC_009801.1 identified by glimmer; hypothetical protein 2082184 5590021 EcE24377A_2104 Escherichia coli E24377A hypothetical protein YP_001463176.1 2082038 D 331111 CDS YP_001463177.1 157157392 5586682 complement(2082175..2084622) 1 NC_009801.1 identified by similarity to SP:P46923; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409; trimethylamine N-oxide reductase III subunit TorZ 2084622 torZ 5586682 torZ Escherichia coli E24377A trimethylamine N-oxide reductase III subunit TorZ YP_001463177.1 2082175 R 331111 CDS YP_001463178.1 157156650 5590576 complement(2084629..2085729) 1 NC_009801.1 identified by similarity to SP:P52005; match to protein family HMM PF03264; trimethylamine N-oxide reductase III, c-type cytochrome subunit TorY 2085729 torY 5590576 torY Escherichia coli E24377A trimethylamine N-oxide reductase III, c-type cytochrome subunit TorY YP_001463178.1 2084629 R 331111 CDS YP_001463179.1 157155916 5590638 complement(2086117..2086863) 1 NC_009801.1 identified by match to protein family HMM PF03932; copper homeostasis protein CutC 2086863 cutC 5590638 cutC Escherichia coli E24377A copper homeostasis protein CutC YP_001463179.1 2086117 R 331111 CDS YP_001463180.1 157155063 5589580 complement(2086877..2087449) 1 NC_009801.1 identified by similarity to GB:AAL20824.1; match to protein family HMM PF06185; hypothetical protein 2087449 5589580 EcE24377A_2107 Escherichia coli E24377A hypothetical protein YP_001463180.1 2086877 R 331111 CDS YP_001463181.1 157158431 5586887 2087659..2089392 1 NC_009801.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2089392 argS 5586887 argS Escherichia coli E24377A arginyl-tRNA synthetase YP_001463181.1 2087659 D 331111 CDS YP_001463182.1 157155222 5589059 2089569..2090057 1 NC_009801.1 identified by match to protein family HMM PF07007; hypothetical protein 2090057 5589059 EcE24377A_2109 Escherichia coli E24377A hypothetical protein YP_001463182.1 2089569 D 331111 CDS YP_001463183.1 157157131 5590453 complement(2090177..2090569) 1 NC_009801.1 identified by similarity to SP:P76297; match to protein family HMM PF06366; flagellar protein FlhE 2090569 flhE 5590453 flhE Escherichia coli E24377A flagellar protein FlhE YP_001463183.1 2090177 R 331111 CDS YP_001463184.1 157158952 5589984 complement(2090569..2092647) 1 NC_009801.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 2092647 flhA 5589984 flhA Escherichia coli E24377A flagellar biosynthesis protein FlhA YP_001463184.1 2090569 R 331111 CDS YP_001463185.1 157156351 5587138 complement(2092640..2093788) 1 NC_009801.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 2093788 flhB 5587138 flhB Escherichia coli E24377A flagellar biosynthesis protein FlhB YP_001463185.1 2092640 R 331111 CDS YP_001463186.1 157155449 5587543 2093821..2093955 1 NC_009801.1 identified by glimmer; hypothetical protein 2093955 5587543 EcE24377A_2113 Escherichia coli E24377A hypothetical protein YP_001463186.1 2093821 D 331111 CDS YP_001463187.1 157158816 5588220 complement(2093990..2094634) 1 NC_009801.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 2094634 cheZ 5588220 cheZ Escherichia coli E24377A chemotaxis regulator CheZ YP_001463187.1 2093990 R 331111 CDS YP_001463188.1 157159376 5588305 complement(2094645..2095034) 1 NC_009801.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 2095034 cheY 5588305 cheY Escherichia coli E24377A chemotaxis regulatory protein CheY YP_001463188.1 2094645 R 331111 CDS YP_001463189.1 157157545 5588888 complement(2095049..2096098) 1 NC_009801.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 2096098 cheB 5588888 cheB Escherichia coli E24377A chemotaxis-specific methylesterase YP_001463189.1 2095049 R 331111 CDS YP_001463190.1 157158073 5587473 complement(2096101..2096961) 1 NC_009801.1 methylates the MCP; chemotaxis methyltransferase CheR 2096961 cheR 5587473 cheR Escherichia coli E24377A chemotaxis methyltransferase CheR YP_001463190.1 2096101 R 331111 CDS YP_001463191.1 157155121 5587577 complement(2096980..2098581) 1 NC_009801.1 mediates taxis toward dipeptides; methyl-accepting protein IV 2098581 5587577 EcE24377A_2118 Escherichia coli E24377A methyl-accepting protein IV YP_001463191.1 2096980 R 331111 CDS YP_001463192.1 157157023 5586642 complement(2098627..2100288) 1 NC_009801.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203; methyl-accepting chemotaxis protein II 2100288 cheM 5586642 cheM Escherichia coli E24377A methyl-accepting chemotaxis protein II YP_001463192.1 2098627 R 331111 CDS YP_001463193.1 157155275 5590254 complement(2100433..2100936) 1 NC_009801.1 identified by match to protein family HMM PF01584; purine-binding chemotaxis protein 2100936 cheW 5590254 cheW Escherichia coli E24377A purine-binding chemotaxis protein YP_001463193.1 2100433 R 331111 CDS YP_001463194.1 157155369 5587109 complement(2100957..2102921) 1 NC_009801.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA 2102921 cheA 5587109 cheA Escherichia coli E24377A chemotaxis protein CheA YP_001463194.1 2100957 R 331111 CDS YP_001463195.1 157158423 5588052 complement(2102926..2103852) 1 NC_009801.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 2103852 motB 5588052 motB Escherichia coli E24377A flagellar motor protein MotB YP_001463195.1 2102926 R 331111 CDS YP_001463196.1 157156438 5589375 complement(2103849..2104736) 1 NC_009801.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 2104736 motA 5589375 motA Escherichia coli E24377A flagellar motor protein MotA YP_001463196.1 2103849 R 331111 CDS YP_001463197.1 157158289 5589187 complement(2104863..2105441) 1 NC_009801.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC 2105441 flhC 5589187 flhC Escherichia coli E24377A transcriptional activator FlhC YP_001463197.1 2104863 R 331111 CDS YP_001463198.1 157158974 5590412 complement(2105444..2105794) 1 NC_009801.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD 2105794 flhD 5590412 flhD Escherichia coli E24377A transcriptional activator FlhD YP_001463198.1 2105444 R 331111 CDS YP_001463199.1 157158094 5589060 complement(2105825..2105923) 1 NC_009801.1 identified by glimmer; hypothetical protein 2105923 5589060 EcE24377A_2126 Escherichia coli E24377A hypothetical protein YP_001463199.1 2105825 R 331111 CDS YP_001463200.1 157157891 5590223 2106574..2107002 1 NC_009801.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 2107002 uspC 5590223 uspC Escherichia coli E24377A universal stress protein UspC YP_001463200.1 2106574 D 331111 CDS YP_001463201.1 157157530 5589913 complement(2107009..2108433) 1 NC_009801.1 identified by match to protein family HMM PF00982; match to protein family HMM TIGR02400; trehalose-6-phosphate synthase 2108433 otsA 5589913 otsA Escherichia coli E24377A trehalose-6-phosphate synthase YP_001463201.1 2107009 R 331111 CDS YP_001463202.1 157158032 5589403 complement(2108408..2109208) 1 NC_009801.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase 2109208 otsB 5589403 otsB Escherichia coli E24377A trehalose-6-phosphate phosphatase YP_001463202.1 2108408 R 331111 CDS YP_001463203.1 157156388 5587198 complement(2109375..2110361) 1 NC_009801.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease 2110361 araH 5587198 araH Escherichia coli E24377A L-arabinose transporter permease YP_001463203.1 2109375 R 331111 CDS YP_001463204.1 157156751 5587532 complement(2110376..2111890) 1 NC_009801.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 2111890 araG 5587532 araG Escherichia coli E24377A L-arabinose transporter ATP-binding protein YP_001463204.1 2110376 R 331111 CDS YP_001463205.1 157159136 5585995 complement(2111960..2112949) 1 NC_009801.1 identified by match to protein family HMM PF00532; L-arabinose ABC transporter periplasmic L-arabinose-binding protein 2112949 araF 5585995 araF Escherichia coli E24377A L-arabinose ABC transporter periplasmic L-arabinose-binding protein YP_001463205.1 2111960 R 331111 CDS YP_001463206.1 157157170 5588260 2113746..2114249 1 NC_009801.1 identified by match to protein family HMM PF00210; ferritin 2114249 5588260 EcE24377A_2133 Escherichia coli E24377A ferritin YP_001463206.1 2113746 D 331111 CDS YP_001463208.1 157159230 5589838 2114691..2114837 1 NC_009801.1 identified by glimmer; hypothetical protein 2114837 5589838 EcE24377A_2135 Escherichia coli E24377A hypothetical protein YP_001463208.1 2114691 D 331111 CDS YP_001463209.1 157158465 5586315 2115043..2115366 1 NC_009801.1 lipoprotein 2115366 5586315 EcE24377A_2136 Escherichia coli E24377A lipoprotein YP_001463209.1 2115043 D 331111 CDS YP_001463210.1 157159103 5586670 complement(2115372..2115512) 1 NC_009801.1 identified by glimmer; hypothetical protein 2115512 5586670 EcE24377A_2137 Escherichia coli E24377A hypothetical protein YP_001463210.1 2115372 R 331111 CDS YP_001463211.1 157157135 5587929 2115537..2116034 1 NC_009801.1 cytoplasmic iron storage protein; ferritin 2116034 ftnA 5587929 ftnA Escherichia coli E24377A ferritin YP_001463211.1 2115537 D 331111 CDS YP_001463212.1 157157760 5589280 complement(2116072..2116311) 1 NC_009801.1 identified by similarity to SP:P46887; hypothetical protein 2116311 5589280 EcE24377A_2139 Escherichia coli E24377A hypothetical protein YP_001463212.1 2116072 R 331111 CDS YP_001463213.1 157155688 5589087 2116502..2117713 1 NC_009801.1 identified by match to protein family HMM PF01490; match to protein family HMM PF03222; match to protein family HMM TIGR00837; tyrosine-specific transport protein 2117713 tyrP 5589087 tyrP Escherichia coli E24377A tyrosine-specific transport protein YP_001463213.1 2116502 D 331111 CDS YP_001463214.1 157159261 5588764 complement(2117775..2118440) 1 NC_009801.1 identified by match to protein family HMM PF02810; match to protein family HMM TIGR02292; hypothetical protein 2118440 5588764 EcE24377A_2141 Escherichia coli E24377A hypothetical protein YP_001463214.1 2117775 R 331111 CDS YP_001463215.1 157154766 5587026 complement(2119090..2119638) 1 NC_009801.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; phosphatidylglycerophosphate synthetase 2119638 pgsA 5587026 pgsA Escherichia coli E24377A phosphatidylglycerophosphate synthetase YP_001463215.1 2119090 R 331111 CDS YP_001463216.1 157155145 5587924 complement(2119695..2121527) 1 NC_009801.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 2121527 uvrC 5587924 uvrC Escherichia coli E24377A excinuclease ABC subunit C YP_001463216.1 2119695 R 331111 CDS YP_001463217.1 157156123 5589434 complement(2121524..2122180) 1 NC_009801.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 2122180 uvrY 5589434 uvrY Escherichia coli E24377A response regulator YP_001463217.1 2121524 R 331111 CDS YP_001463218.1 157156811 5585911 complement(2122419..2122547) 1 NC_009801.1 hypothetical protein 2122547 5585911 EcE24377A_2148 Escherichia coli E24377A hypothetical protein YP_001463218.1 2122419 R 331111 CDS YP_001463219.1 157155339 5586864 2122639..2122863 1 NC_009801.1 identified by similarity to SP:P0AD09; hypothetical protein 2122863 5586864 EcE24377A_2149 Escherichia coli E24377A hypothetical protein YP_001463219.1 2122639 D 331111 CDS YP_001463220.1 157156210 5588254 complement(2122930..2123652) 1 NC_009801.1 regulates genes involved in cell division; DNA-binding transcriptional activator SdiA 2123652 sdiA 5588254 sdiA Escherichia coli E24377A DNA-binding transcriptional activator SdiA YP_001463220.1 2122930 R 331111 CDS YP_001463221.1 157156999 5587802 complement(2123882..2124634) 1 NC_009801.1 identified by match to protein family HMM PF00005; amino-acid ABC transporter ATP-binding protein YecC 2124634 yecC 5587802 yecC Escherichia coli E24377A amino-acid ABC transporter ATP-binding protein YecC YP_001463221.1 2123882 R 331111 CDS YP_001463222.1 157157239 5586444 complement(2124631..2125299) 1 NC_009801.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; L-cystine ABC transporter permease 2125299 5586444 EcE24377A_2152 Escherichia coli E24377A L-cystine ABC transporter permease YP_001463222.1 2124631 R 331111 CDS YP_001463223.1 157157688 5587919 complement(2125271..2126299) 1 NC_009801.1 catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 2126299 dcyD 5587919 dcyD Escherichia coli E24377A D-cysteine desulfhydrase YP_001463223.1 2125271 R 331111 CDS YP_001463224.1 157156974 5590514 complement(2126404..2127204) 1 NC_009801.1 identified by match to protein family HMM PF00497; cystine transporter subunit 2127204 fliY 5590514 fliY Escherichia coli E24377A cystine transporter subunit YP_001463224.1 2126404 R 331111 CDS YP_001463225.1 157157001 5590057 complement(2127328..2127843) 1 NC_009801.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 2127843 5590057 EcE24377A_2155 Escherichia coli E24377A flagella biosynthesis protein FliZ YP_001463225.1 2127328 R 331111 CDS YP_001463226.1 157158016 5586823 complement(2127889..2128608) 1 NC_009801.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 2128608 fliA 5586823 fliA Escherichia coli E24377A flagellar biosynthesis sigma factor YP_001463226.1 2127889 R 331111 CDS YP_001463227.1 157157356 5589560 complement(2128679..2128879) 1 NC_009801.1 identified by glimmer; hypothetical protein 2128879 5589560 EcE24377A_2157 Escherichia coli E24377A hypothetical protein YP_001463227.1 2128679 R 331111 CDS YP_001463228.1 157159035 5586916 complement(2128928..2130667) 1 NC_009801.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin 2130667 fliC 5586916 fliC Escherichia coli E24377A flagellin YP_001463228.1 2128928 R 331111 CDS YP_001463229.1 157159311 5587946 2130933..2132339 1 NC_009801.1 involved in flagellin assembly; flagellar capping protein 2132339 fliD 5587946 fliD Escherichia coli E24377A flagellar capping protein YP_001463229.1 2130933 D 331111 CDS YP_001463230.1 157154901 5588852 2132364..2132774 1 NC_009801.1 flagellin specific chaperone; flagellar protein FliS 2132774 fliS 5588852 fliS Escherichia coli E24377A flagellar protein FliS YP_001463230.1 2132364 D 331111 CDS YP_001463231.1 157155573 5590115 2132774..2133139 1 NC_009801.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2133139 fliT 5590115 fliT Escherichia coli E24377A flagellar biosynthesis protein FliT YP_001463231.1 2132774 D 331111 CDS YP_001463232.1 157155959 5589383 2133217..2134704 1 NC_009801.1 converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 2134704 amyA 5589383 amyA Escherichia coli E24377A alpha-amylase YP_001463232.1 2133217 D 331111 CDS YP_001463233.1 157155931 5586578 complement(2134738..2135154) 1 NC_009801.1 hypothetical protein 2135154 5586578 EcE24377A_2163 Escherichia coli E24377A hypothetical protein YP_001463233.1 2134738 R 331111 CDS YP_001463234.1 157156120 5586731 2135338..2136543 1 NC_009801.1 identified by match to protein family HMM PF04143; inner membrane protein 2136543 5586731 EcE24377A_2164 Escherichia coli E24377A inner membrane protein YP_001463234.1 2135338 D 331111 CDS YP_001463235.1 157156285 5587611 2136540..2136773 1 NC_009801.1 identified by match to protein family HMM PF01206; hypothetical protein 2136773 5587611 EcE24377A_2165 Escherichia coli E24377A hypothetical protein YP_001463235.1 2136540 D 331111 CDS YP_001463236.1 157157474 5590207 2136882..2137553 1 NC_009801.1 identified by similarity to GB:AAG56946.1; match to protein family HMM PF02586; hypothetical protein 2137553 5590207 EcE24377A_2167 Escherichia coli E24377A hypothetical protein YP_001463236.1 2136882 D 331111 CDS YP_001463237.1 157158236 5585939 complement(2137538..2138701) 1 NC_009801.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766; IS605 family transposase OrfB 2138701 5585939 EcE24377A_2166 Escherichia coli E24377A IS605 family transposase OrfB YP_001463237.1 2137538 R 331111 CDS YP_001463238.1 157157515 5588545 complement(2140090..2140887) 1 NC_009801.1 AraC family transcriptional regulator 2140887 5588545 EcE24377A_2169 Escherichia coli E24377A AraC family transcriptional regulator YP_001463238.1 2140090 R 331111 CDS YP_001463239.1 157159221 5589817 complement(2142283..2142597) 1 NC_009801.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 2142597 fliE 5589817 fliE Escherichia coli E24377A flagellar hook-basal body protein FliE YP_001463239.1 2142283 R 331111 CDS YP_001463240.1 157158866 5590716 2142812..2144470 1 NC_009801.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2144470 fliF 5590716 fliF Escherichia coli E24377A flagellar MS-ring protein YP_001463240.1 2142812 D 331111 CDS YP_001463241.1 157156579 5588558 2144463..2145458 1 NC_009801.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2145458 fliG 5588558 fliG Escherichia coli E24377A flagellar motor switch protein G YP_001463241.1 2144463 D 331111 CDS YP_001463242.1 157157387 5586314 2145451..2146137 1 NC_009801.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2146137 fliH 5586314 fliH Escherichia coli E24377A flagellar assembly protein H YP_001463242.1 2145451 D 331111 CDS YP_001463243.1 157158932 5589775 2146137..2147510 1 NC_009801.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2147510 fliI 5589775 fliI Escherichia coli E24377A flagellum-specific ATP synthase YP_001463243.1 2146137 D 331111 CDS YP_001463244.1 157154985 5586137 2147529..2147972 1 NC_009801.1 rod/hook and filament chaperone; flagellar biosynthesis chaperone 2147972 fliJ 5586137 fliJ Escherichia coli E24377A flagellar biosynthesis chaperone YP_001463244.1 2147529 D 331111 CDS YP_001463245.1 157157886 5587347 2147969..2149096 1 NC_009801.1 identified by similarity to SP:P52614; match to protein family HMM PF02120; flagellar hook-length control protein 2149096 fliK 5587347 fliK Escherichia coli E24377A flagellar hook-length control protein YP_001463245.1 2147969 D 331111 CDS YP_001463246.1 157158713 5590633 2149201..2149665 1 NC_009801.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body protein FliL 2149665 fliL 5590633 fliL Escherichia coli E24377A flagellar basal body protein FliL YP_001463246.1 2149201 D 331111 CDS YP_001463247.1 157156914 5589633 2149670..2150674 1 NC_009801.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2150674 fliM 5589633 fliM Escherichia coli E24377A flagellar motor switch protein FliM YP_001463247.1 2149670 D 331111 CDS YP_001463248.1 157157681 5589716 2150671..2151084 1 NC_009801.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2151084 fliN 5589716 fliN Escherichia coli E24377A flagellar motor switch protein FliN YP_001463248.1 2150671 D 331111 CDS YP_001463249.1 157155995 5590552 2151087..2151452 1 NC_009801.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2151452 fliO 5590552 fliO Escherichia coli E24377A flagellar biosynthesis protein FliO YP_001463249.1 2151087 D 331111 CDS YP_001463250.1 157156523 5587069 2151452..2152189 1 NC_009801.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2152189 fliP 5587069 fliP Escherichia coli E24377A flagellar biosynthesis protein FliP YP_001463250.1 2151452 D 331111 CDS YP_001463251.1 157157753 5590232 2152199..2152468 1 NC_009801.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2152468 fliQ 5590232 fliQ Escherichia coli E24377A flagellar biosynthesis protein FliQ YP_001463251.1 2152199 D 331111 CDS YP_001463252.1 157156975 5587186 2152477..2153262 1 NC_009801.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2153262 fliR 5587186 fliR Escherichia coli E24377A flagellar biosynthesis protein FliR YP_001463252.1 2152477 D 331111 CDS YP_001463253.1 157157311 5590058 2153552..2154175 1 NC_009801.1 identified by match to protein family HMM PF00196; colanic acid capsular biosynthesis activation protein A 2154175 rcsA 5590058 rcsA Escherichia coli E24377A colanic acid capsular biosynthesis activation protein A YP_001463253.1 2153552 D 331111 CDS YP_001463254.1 157156352 5585934 complement(2154219..2154407) 1 NC_009801.1 identified by similarity to OMNI:NTL01SF1877; hypothetical protein 2154407 5585934 EcE24377A_2185 Escherichia coli E24377A hypothetical protein YP_001463254.1 2154219 R 331111 CDS YP_001463255.1 157157986 5587013 2154570..2154797 1 NC_009801.1 hypothetical protein 2154797 5587013 EcE24377A_2186 Escherichia coli E24377A hypothetical protein YP_001463255.1 2154570 D 331111 CDS YP_001463256.1 157158348 5587260 2155095..2155910 1 NC_009801.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2155910 5587260 EcE24377A_2188 Escherichia coli E24377A mannosyl-3-phosphoglycerate phosphatase YP_001463256.1 2155095 D 331111 CDS YP_001463257.1 157155861 5586255 complement(2155907..2157583) 1 NC_009801.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254; diguanylate cyclase 2157583 5586255 EcE24377A_2187 Escherichia coli E24377A diguanylate cyclase YP_001463257.1 2155907 R 331111 CDS YP_001463258.1 157155225 5587989 complement(2157772..2157954) 1 NC_009801.1 identified by similarity to GB:AAP17372.1; hypothetical protein 2157954 5587989 EcE24377A_2189 Escherichia coli E24377A hypothetical protein YP_001463258.1 2157772 R 331111 CDS YP_001463259.1 157156718 5589546 complement(2158033..2158950) 1 NC_009801.1 identified by match to protein family HMM PF05661; hypothetical protein 2158950 5589546 EcE24377A_2190 Escherichia coli E24377A hypothetical protein YP_001463259.1 2158033 R 331111 CDS YP_001463260.1 157159027 5589875 2159123..2160043 1 NC_009801.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950; hypothetical protein 2160043 5589875 EcE24377A_2192 Escherichia coli E24377A hypothetical protein YP_001463260.1 2159123 D 331111 CDS YP_001463261.1 157156160 5589436 complement(2160032..2160502) 1 NC_009801.1 identified by similarity to SP:P09184; match to protein family HMM PF03852; match to protein family HMM TIGR00632; very short patch repair protein 2160502 vsr 5589436 vsr Escherichia coli E24377A very short patch repair protein YP_001463261.1 2160032 R 331111 CDS YP_001463262.1 157158517 5590825 complement(2160483..2161901) 1 NC_009801.1 identified by similarity to SP:P0AED9; match to protein family HMM PF00145; match to protein family HMM TIGR00675; DNA cytosine methylase 2161901 dcm 5590825 dcm Escherichia coli E24377A DNA cytosine methylase YP_001463262.1 2160483 R 331111 CDS YP_001463263.1 157157707 5589267 complement(2161968..2162663) 1 NC_009801.1 identified by match to protein family HMM PF01966; hypothetical protein 2162663 5589267 EcE24377A_2194 Escherichia coli E24377A hypothetical protein YP_001463263.1 2161968 R 331111 CDS YP_001463264.1 157157227 5587758 complement(2162703..2163086) 1 NC_009801.1 hypothetical protein 2163086 5587758 EcE24377A_2195 Escherichia coli E24377A hypothetical protein YP_001463264.1 2162703 R 331111 CDS YP_001463265.1 157157031 5589779 2163070..2163177 1 NC_009801.1 identified by glimmer; hypothetical protein 2163177 5589779 EcE24377A_2196 Escherichia coli E24377A hypothetical protein YP_001463265.1 2163070 D 331111 CDS YP_001463266.1 157156499 5586003 2163636..2164709 1 NC_009801.1 identified by match to protein family HMM PF00267; match to protein family HMM TIGR03304; outer membrane protein 2164709 5586003 EcE24377A_2197 Escherichia coli E24377A outer membrane protein YP_001463266.1 2163636 D 331111 CDS YP_001463267.1 157155671 5588379 2165301..2166152 1 NC_009801.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2166152 hchA 5588379 hchA Escherichia coli E24377A chaperone protein HchA YP_001463267.1 2165301 D 331111 CDS YP_001463268.1 157155012 5587264 complement(2166260..2167618) 1 NC_009801.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386; heavy metal sensor histidine kinase 2167618 5587264 EcE24377A_2199 Escherichia coli E24377A heavy metal sensor histidine kinase YP_001463268.1 2166260 R 331111 CDS YP_001463269.1 157155786 5589565 complement(2167618..2168400) 1 NC_009801.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW 2168400 5589565 EcE24377A_2200 Escherichia coli E24377A transcriptional regulatory protein YedW YP_001463269.1 2167618 R 331111 CDS YP_001463270.1 157155062 5587696 2168422..2168835 1 NC_009801.1 identified by match to protein family HMM PF00576; match to protein family HMM TIGR02962; transthyretin family protein 2168835 5587696 EcE24377A_2201 Escherichia coli E24377A transthyretin family protein YP_001463270.1 2168422 D 331111 CDS YP_001463271.1 157157814 5586868 2168944..2169948 1 NC_009801.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 2169948 5586868 EcE24377A_2202 Escherichia coli E24377A sulfite oxidase subunit YedY YP_001463271.1 2168944 D 331111 CDS YP_001463272.1 157157117 5587012 2169949..2170584 1 NC_009801.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 2170584 5587012 EcE24377A_2203 Escherichia coli E24377A sulfite oxidase subunit YedZ YP_001463272.1 2169949 D 331111 CDS YP_001463273.1 157159146 5590672 2170841..2171491 1 NC_009801.1 identified by similarity to SP:P76344; match to protein family HMM PF09223; hypothetical protein 2171491 5590672 EcE24377A_2204 Escherichia coli E24377A hypothetical protein YP_001463273.1 2170841 D 331111 CDS YP_001463274.1 157158519 5589719 2171834..2172364 1 NC_009801.1 identified by match to protein family HMM PF01292; nickel-dependent hydrogenase, b-type cytochrome subunit 2172364 5589719 EcE24377A_2205 Escherichia coli E24377A nickel-dependent hydrogenase, b-type cytochrome subunit YP_001463274.1 2171834 D 331111 CDS YP_001463275.1 157155080 5590537 complement(2173089..2173205) 1 NC_009801.1 identified by glimmer; hypothetical protein 2173205 5590537 EcE24377A_2206 Escherichia coli E24377A hypothetical protein YP_001463275.1 2173089 R 331111 CDS YP_001463276.1 157159341 5590540 complement(2173343..2174353) 1 NC_009801.1 identified by similarity to SP:P03764; match to protein family HMM PF08400; tail fiber family protein 2174353 5590540 EcE24377A_2207 Escherichia coli E24377A tail fiber family protein YP_001463276.1 2173343 R 331111 CDS YP_001463277.1 157159016 5589607 complement(2175399..2175491) 1 NC_009801.1 identified by glimmer; hypothetical protein 2175491 5589607 EcE24377A_2209 Escherichia coli E24377A hypothetical protein YP_001463277.1 2175399 R 331111 CDS YP_001463278.1 157155930 5588213 complement(2176281..2177921) 1 NC_009801.1 hypothetical protein 2177921 5588213 EcE24377A_2210 Escherichia coli E24377A hypothetical protein YP_001463278.1 2176281 R 331111 CDS YP_001463279.1 157156634 5589491 complement(2178030..2178311) 1 NC_009801.1 identified by similarity to GB:AAG04013.1; hypothetical protein 2178311 5589491 EcE24377A_2211 Escherichia coli E24377A hypothetical protein YP_001463279.1 2178030 R 331111 CDS YP_001463280.1 157157565 5590404 complement(2178324..2178836) 1 NC_009801.1 hypothetical protein 2178836 5590404 EcE24377A_2212 Escherichia coli E24377A hypothetical protein YP_001463280.1 2178324 R 331111 CDS YP_001463281.1 157158271 5588472 complement(2178854..2180359) 1 NC_009801.1 identified by similarity to SP:P22501; match to protein family HMM PF04984; major tail sheath protein 2180359 5588472 EcE24377A_2213 Escherichia coli E24377A major tail sheath protein YP_001463281.1 2178854 R 331111 CDS YP_001463282.1 157158614 5588034 complement(2180371..2181519) 1 NC_009801.1 identified by glimmer; hypothetical protein 2181519 5588034 EcE24377A_2214 Escherichia coli E24377A hypothetical protein YP_001463282.1 2180371 R 331111 CDS YP_001463283.1 157157340 5589072 complement(2181512..2182138) 1 NC_009801.1 identified by match to protein family HMM TIGR01634; phage tail protein I 2182138 5589072 EcE24377A_2215 Escherichia coli E24377A phage tail protein I YP_001463283.1 2181512 R 331111 CDS YP_001463284.1 157155511 5586566 complement(2182141..2183031) 1 NC_009801.1 identified by similarity to SP:P51767; match to protein family HMM PF04865; baseplate assembly protein J 2183031 5586566 EcE24377A_2216 Escherichia coli E24377A baseplate assembly protein J YP_001463284.1 2182141 R 331111 CDS YP_001463285.1 157158418 5590782 complement(2183058..2183399) 1 NC_009801.1 identified by similarity to SP:P51768; match to protein family HMM PF04965; baseplate assembly protein W 2183399 5590782 EcE24377A_2217 Escherichia coli E24377A baseplate assembly protein W YP_001463285.1 2183058 R 331111 CDS YP_001463286.1 157157570 5586194 complement(2183402..2184307) 1 NC_009801.1 identified by similarity to SP:P31340; match to protein family HMM PF04717; match to protein family HMM TIGR01644; phage baseplate assembly protein V 2184307 5586194 EcE24377A_2218 Escherichia coli E24377A phage baseplate assembly protein V YP_001463286.1 2183402 R 331111 CDS YP_001463287.1 157159003 5586201 complement(2184288..2184824) 1 NC_009801.1 identified by glimmer; hypothetical protein 2184824 5586201 EcE24377A_2219 Escherichia coli E24377A hypothetical protein YP_001463287.1 2184288 R 331111 CDS YP_001463288.1 157155419 5588090 complement(2184821..2185474) 1 NC_009801.1 identified by glimmer; hypothetical protein 2185474 5588090 EcE24377A_2220 Escherichia coli E24377A hypothetical protein YP_001463288.1 2184821 R 331111 CDS YP_001463289.1 157154756 5587075 complement(2185533..2185913) 1 NC_009801.1 identified by glimmer; hypothetical protein 2185913 5587075 EcE24377A_2221 Escherichia coli E24377A hypothetical protein YP_001463289.1 2185533 R 331111 CDS YP_001463290.1 157156700 5587306 complement(2185910..2186323) 1 NC_009801.1 identified by similarity to GB:AAC19046.1; hypothetical protein 2186323 5587306 EcE24377A_2222 Escherichia coli E24377A hypothetical protein YP_001463290.1 2185910 R 331111 CDS YP_001463291.1 157156927 5589449 complement(2186358..2187392) 1 NC_009801.1 identified by match to protein family HMM PF03864; phage major capsid protein E 2187392 5589449 EcE24377A_2223 Escherichia coli E24377A phage major capsid protein E YP_001463291.1 2186358 R 331111 CDS YP_001463292.1 157158086 5587235 complement(2187454..2187783) 1 NC_009801.1 identified by match to protein family HMM PF02924; bacteriophage lambda head decoration protein D 2187783 5587235 EcE24377A_2224 Escherichia coli E24377A bacteriophage lambda head decoration protein D YP_001463292.1 2187454 R 331111 CDS YP_001463293.1 157157447 5587059 complement(2187783..2189093) 1 NC_009801.1 identified by match to protein family HMM PF01343; S49 family peptidase 2189093 5587059 EcE24377A_2225 Escherichia coli E24377A S49 family peptidase YP_001463293.1 2187783 R 331111 CDS YP_001463294.1 157158336 5589310 complement(2190088..2190882) 1 NC_009801.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein 2190882 5589310 EcE24377A_2227 Escherichia coli E24377A IS21 family transposition helper protein YP_001463294.1 2190088 R 331111 CDS YP_001463295.1 157157074 5590622 complement(2190882..2192054) 1 NC_009801.1 identified by similarity to SP:P15025; match to protein family HMM PF00665; IS21 family transposase 2192054 5590622 EcE24377A_2228 Escherichia coli E24377A IS21 family transposase YP_001463295.1 2190882 R 331111 CDS YP_001463296.1 157155074 5589405 complement(2193020..2194984) 1 NC_009801.1 identified by match to protein family HMM PF05876; phage terminase large subunit (GpA) 2194984 5589405 EcE24377A_2230 Escherichia coli E24377A phage terminase large subunit (GpA) YP_001463296.1 2193020 R 331111 CDS YP_001463297.1 157155747 5587891 2196342..2196812 1 NC_009801.1 identified by glimmer; hypothetical protein 2196812 5587891 EcE24377A_2231 Escherichia coli E24377A hypothetical protein YP_001463297.1 2196342 D 331111 CDS YP_001463298.1 157157783 5586957 complement(2197435..2197914) 1 NC_009801.1 identified by match to protein family HMM TIGR02594; hypothetical protein 2197914 5586957 EcE24377A_2232 Escherichia coli E24377A hypothetical protein YP_001463298.1 2197435 R 331111 CDS YP_001463299.1 157158484 5590474 complement(2198594..2199265) 1 NC_009801.1 identified by match to protein family HMM PF06323; phage antitermination protein Q 2199265 5590474 EcE24377A_2233 Escherichia coli E24377A phage antitermination protein Q YP_001463299.1 2198594 R 331111 CDS YP_001463300.1 157157119 5590370 complement(2199265..2199558) 1 NC_009801.1 identified by match to protein family HMM PF07102; hypothetical protein 2199558 5590370 EcE24377A_2234 Escherichia coli E24377A hypothetical protein YP_001463300.1 2199265 R 331111 CDS YP_001463301.1 157157761 5589841 complement(2199555..2200151) 1 NC_009801.1 identified by similarity to GB:AAX66528.1; match to protein family HMM PF07105; hypothetical protein 2200151 5589841 EcE24377A_2235 Escherichia coli E24377A hypothetical protein YP_001463301.1 2199555 R 331111 CDS YP_001463302.1 157156410 5589088 complement(2200560..2201201) 1 NC_009801.1 identified by glimmer; hypothetical protein 2201201 5589088 EcE24377A_2236 Escherichia coli E24377A hypothetical protein YP_001463302.1 2200560 R 331111 CDS YP_001463303.1 157157069 5590849 2201711..2202490 1 NC_009801.1 identified by glimmer; hypothetical protein 2202490 5590849 EcE24377A_2237 Escherichia coli E24377A hypothetical protein YP_001463303.1 2201711 D 331111 CDS YP_001463304.1 157156672 5588130 complement(2203954..2205333) 1 NC_009801.1 identified by glimmer; hypothetical protein 2205333 5588130 EcE24377A_2238 Escherichia coli E24377A hypothetical protein YP_001463304.1 2203954 R 331111 CDS YP_001463305.1 157155971 5590504 2205659..2206465 1 NC_009801.1 identified by similarity to GB:AAX67604.1; hypothetical protein 2206465 5590504 EcE24377A_2239 Escherichia coli E24377A hypothetical protein YP_001463305.1 2205659 D 331111 CDS YP_001463306.1 157159446 5587505 2206431..2206544 1 NC_009801.1 identified by glimmer; hypothetical protein 2206544 5587505 EcE24377A_2240 Escherichia coli E24377A hypothetical protein YP_001463306.1 2206431 D 331111 CDS YP_001463307.1 157157782 5589416 2206546..2207781 1 NC_009801.1 identified by glimmer; hypothetical protein 2207781 5589416 EcE24377A_2241 Escherichia coli E24377A hypothetical protein YP_001463307.1 2206546 D 331111 CDS YP_001463308.1 157158117 5588513 2207913..2208473 1 NC_009801.1 lipoprotein 2208473 5588513 EcE24377A_2242 Escherichia coli E24377A lipoprotein YP_001463308.1 2207913 D 331111 CDS YP_001463309.1 157157453 5587090 2208926..2209849 1 NC_009801.1 lipoprotein 2209849 5587090 EcE24377A_2243 Escherichia coli E24377A lipoprotein YP_001463309.1 2208926 D 331111 CDS YP_001463310.1 157156085 5586270 complement(2210027..2210821) 1 NC_009801.1 hypothetical protein 2210821 5586270 EcE24377A_2244 Escherichia coli E24377A hypothetical protein YP_001463310.1 2210027 R 331111 CDS YP_001463311.1 157155696 5590878 complement(2211503..2211727) 1 NC_009801.1 identified by glimmer; hypothetical protein 2211727 5590878 EcE24377A_2245 Escherichia coli E24377A hypothetical protein YP_001463311.1 2211503 R 331111 CDS YP_001463312.1 157154778 5587914 complement(2211724..2211957) 1 NC_009801.1 identified by glimmer; hypothetical protein 2211957 5587914 EcE24377A_2246 Escherichia coli E24377A hypothetical protein YP_001463312.1 2211724 R 331111 CDS YP_001463313.1 157159115 5590807 complement(2211957..2212358) 1 NC_009801.1 identified by similarity to GB:AAT84997.1; hypothetical protein 2212358 5590807 EcE24377A_2247 Escherichia coli E24377A hypothetical protein YP_001463313.1 2211957 R 331111 CDS YP_001463314.1 157156830 5587175 complement(2212397..2213788) 1 NC_009801.1 identified by match to protein family HMM PF03796; DnaB family helicase 2213788 5587175 EcE24377A_2248 Escherichia coli E24377A DnaB family helicase YP_001463314.1 2212397 R 331111 CDS YP_001463315.1 157156443 5586330 complement(2213785..2214849) 1 NC_009801.1 hypothetical protein 2214849 5586330 EcE24377A_2249 Escherichia coli E24377A hypothetical protein YP_001463315.1 2213785 R 331111 CDS YP_001463316.1 157155209 5590297 complement(2214852..2215076) 1 NC_009801.1 identified by similarity to GB:CAE15847.1; hypothetical protein 2215076 5590297 EcE24377A_2250 Escherichia coli E24377A hypothetical protein YP_001463316.1 2214852 R 331111 CDS YP_001463317.1 157159357 5587352 complement(2215116..2215592) 1 NC_009801.1 identified by similarity to GB:CAE15848.1; match to protein family HMM PF06254; hypothetical protein 2215592 5587352 EcE24377A_2251 Escherichia coli E24377A hypothetical protein YP_001463317.1 2215116 R 331111 CDS YP_001463318.1 157158980 5590652 2215936..2216331 1 NC_009801.1 The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown.; transcriptional repressor DicA 2216331 5590652 EcE24377A_2252 Escherichia coli E24377A transcriptional repressor DicA YP_001463318.1 2215936 D 331111 CDS YP_001463319.1 157158297 5589277 2216941..2219007 1 NC_009801.1 identified by glimmer; hypothetical protein 2219007 5589277 EcE24377A_2253 Escherichia coli E24377A hypothetical protein YP_001463319.1 2216941 D 331111 CDS YP_001463320.1 157157111 5589694 2219004..2219573 1 NC_009801.1 identified by similarity to GB:CAE15856.1; hypothetical protein 2219573 5589694 EcE24377A_2254 Escherichia coli E24377A hypothetical protein YP_001463320.1 2219004 D 331111 CDS YP_001463321.1 157156769 5590545 2219573..2219755 1 NC_009801.1 identified by glimmer; hypothetical protein 2219755 5590545 EcE24377A_2255 Escherichia coli E24377A hypothetical protein YP_001463321.1 2219573 D 331111 CDS YP_001463322.1 157156096 5589545 2219965..2220180 1 NC_009801.1 identified by similarity to GB:AAN69513.1; hypothetical protein 2220180 5589545 EcE24377A_2256 Escherichia coli E24377A hypothetical protein YP_001463322.1 2219965 D 331111 CDS YP_001463323.1 157158542 5586162 2220180..2221208 1 NC_009801.1 identified by match to protein family HMM PF00589; phage integrase site specific recombinase 2221208 5586162 EcE24377A_2257 Escherichia coli E24377A phage integrase site specific recombinase YP_001463323.1 2220180 D 331111 CDS YP_001463324.1 157159031 5587354 2221477..2222274 1 NC_009801.1 identified by similarity to SP:P76346; match to protein family HMM PF06167; hypothetical protein 2222274 5587354 EcE24377A_2259 Escherichia coli E24377A hypothetical protein YP_001463324.1 2221477 D 331111 CDS YP_001463325.1 157155108 5588891 2222950..2229840 1 NC_009801.1 identified by similarity to SP:P11922; match to protein family HMM PF00801; match to protein family HMM PF02369; invasin 2229840 5588891 EcE24377A_2261 Escherichia coli E24377A invasin YP_001463325.1 2222950 D 331111 CDS YP_001463326.1 157155629 5587977 complement(2230102..2231154) 1 NC_009801.1 hypothetical protein 2231154 5587977 EcE24377A_2262 Escherichia coli E24377A hypothetical protein YP_001463326.1 2230102 R 331111 CDS YP_001463327.1 157156154 5585967 2231469..2232785 1 NC_009801.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883; shikimate transporter 2232785 shiA 5585967 shiA Escherichia coli E24377A shikimate transporter YP_001463327.1 2231469 D 331111 CDS YP_001463328.1 157156969 5585924 2232887..2234341 1 NC_009801.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2234341 amn 5585924 amn Escherichia coli E24377A AMP nucleosidase YP_001463328.1 2232887 D 331111 CDS YP_001463329.1 157157475 5587332 2234684..2235400 1 NC_009801.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 2235400 5587332 EcE24377A_2265 Escherichia coli E24377A hypothetical protein YP_001463329.1 2234684 D 331111 CDS YP_001463330.1 157158251 5588875 complement(2236030..2237670) 1 NC_009801.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; hypothetical protein 2237670 5588875 EcE24377A_2267 Escherichia coli E24377A hypothetical protein YP_001463330.1 2236030 R 331111 CDS YP_001463331.1 157158758 5586049 complement(2237791..2238741) 1 NC_009801.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 2238741 cbl 5586049 cbl Escherichia coli E24377A transcriptional regulator Cbl YP_001463331.1 2237791 R 331111 CDS YP_001463332.1 157158368 5590859 complement(2238843..2239760) 1 NC_009801.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 2239760 nac 5590859 nac Escherichia coli E24377A nitrogen assimilation transcriptional regulator YP_001463332.1 2238843 R 331111 CDS YP_001463333.1 157155230 5588874 complement(2240218..2241150) 1 NC_009801.1 identified by match to protein family HMM PF03734; hypothetical protein 2241150 5588874 EcE24377A_2272 Escherichia coli E24377A hypothetical protein YP_001463333.1 2240218 R 331111 CDS YP_001463334.1 157157289 5589336 complement(2241215..2242294) 1 NC_009801.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2242294 cobT 5589336 cobT Escherichia coli E24377A nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_001463334.1 2241215 R 331111 CDS YP_001463335.1 157157942 5586672 complement(2242306..2243049) 1 NC_009801.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 2243049 cobS 5586672 cobS Escherichia coli E24377A cobalamin synthase YP_001463335.1 2242306 R 331111 CDS YP_001463336.1 157156453 5589573 complement(2243046..2243591) 1 NC_009801.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase 2243591 cobU 5589573 cobU Escherichia coli E24377A adenosylcobinamide kinase YP_001463336.1 2243046 R 331111 CDS YP_001463337.1 157156911 5588269 complement(2243725..2244162) 1 NC_009801.1 identified by similarity to SP:Q05631; cobalamin biosynthesis family protein 2244162 5588269 EcE24377A_2276 Escherichia coli E24377A cobalamin biosynthesis family protein YP_001463337.1 2243725 R 331111 CDS YP_001463338.1 157155157 5588552 complement(2244644..2245558) 1 NC_009801.1 identified by similarity to SP:Q05587; match to protein family HMM PF00165; regulatory protein PocR 2245558 pocR 5588552 pocR Escherichia coli E24377A regulatory protein PocR YP_001463338.1 2244644 R 331111 CDS YP_001463339.1 157155813 5590844 complement(2245761..2246570) 1 NC_009801.1 identified by similarity to SP:P37451; match to protein family HMM PF00230; match to protein family HMM TIGR00861; propanediol diffusion facilitator 2246570 pduF 5590844 pduF Escherichia coli E24377A propanediol diffusion facilitator YP_001463339.1 2245761 R 331111 CDS YP_001463340.1 157158321 5586496 2247082..2247366 1 NC_009801.1 identified by similarity to SP:P0A1C7; match to protein family HMM PF00936; propanediol utilization protein PduA 2247366 pduA 5586496 pduA Escherichia coli E24377A propanediol utilization protein PduA YP_001463340.1 2247082 D 331111 CDS YP_001463341.1 157159004 5587756 2247474..2248175 1 NC_009801.1 identified by similarity to SP:P37449; match to protein family HMM PF00936; propanediol utilization protein PduB 2248175 pduB 5587756 pduB Escherichia coli E24377A propanediol utilization protein PduB YP_001463341.1 2247474 D 331111 CDS YP_001463342.1 157157290 5587739 2248194..2249858 1 NC_009801.1 identified by similarity to SP:P37450; match to protein family HMM PF02286; propanediol utilization dehydratase, large subunit 2249858 pduC 5587739 pduC Escherichia coli E24377A propanediol utilization dehydratase, large subunit YP_001463342.1 2248194 D 331111 CDS YP_001463343.1 157155485 5586673 2249868..2250536 1 NC_009801.1 identified by similarity to GB:AAB84103.1; match to protein family HMM PF02288; propanediol utilization dehydratase, medium subunit 2250536 pduD 5586673 pduD Escherichia coli E24377A propanediol utilization dehydratase, medium subunit YP_001463343.1 2249868 D 331111 CDS YP_001463344.1 157156054 5586833 2250551..2251069 1 NC_009801.1 identified by similarity to GB:AAB84104.1; match to protein family HMM PF02287; propanediol utilization dehydratase, small subunit 2251069 pduE 5586833 pduE Escherichia coli E24377A propanediol utilization dehydratase, small subunit YP_001463344.1 2250551 D 331111 CDS YP_001463345.1 157156561 5588222 2251079..2252911 1 NC_009801.1 identified by similarity to GB:AAB84105.2; match to protein family HMM PF08841; propanediol utilization diol dehydratase reactivation protein 2252911 pduG 5588222 pduG Escherichia coli E24377A propanediol utilization diol dehydratase reactivation protein YP_001463345.1 2251079 D 331111 CDS YP_001463346.1 157159445 5588144 2253271..2253546 1 NC_009801.1 identified by similarity to GB:AAD39009.1; match to protein family HMM PF00936; propanediol utilization protein PduJ 2253546 pduJ 5588144 pduJ Escherichia coli E24377A propanediol utilization protein PduJ YP_001463346.1 2253271 D 331111 CDS YP_001463347.1 157154854 5585977 2253570..2253992 1 NC_009801.1 identified by similarity to GB:AAD39010.1; match to protein family HMM PF00936; propanediol utilization protein PduK 2253992 pduK 5585977 pduK Escherichia coli E24377A propanediol utilization protein PduK YP_001463347.1 2253570 D 331111 CDS YP_001463348.1 157155340 5588811 2253995..2254627 1 NC_009801.1 identified by match to protein family HMM PF06130; propanediol utilization protein PduL 2254627 pduL 5588811 pduL Escherichia coli E24377A propanediol utilization protein PduL YP_001463348.1 2253995 D 331111 CDS YP_001463349.1 157156223 5588255 2254624..2255115 1 NC_009801.1 identified by similarity to GB:AAD39012.1; propanediol utilization protein PduM 2255115 pduM 5588255 pduM Escherichia coli E24377A propanediol utilization protein PduM YP_001463349.1 2254624 D 331111 CDS YP_001463350.1 157156755 5587233 2255119..2255394 1 NC_009801.1 identified by similarity to GB:AAD39013.1; match to protein family HMM PF03319; propanediol utilization protein PduN 2255394 pduN 5587233 pduN Escherichia coli E24377A propanediol utilization protein PduN YP_001463350.1 2255119 D 331111 CDS YP_001463351.1 157158139 5585941 2255406..2256413 1 NC_009801.1 identified by similarity to GB:AAD39014.1; match to protein family HMM PF01923; match to protein family HMM PF03928; match to protein family HMM TIGR00636; propanediol utilization protein, PduO 2256413 pduO 5585941 pduO Escherichia coli E24377A propanediol utilization protein, PduO YP_001463351.1 2255406 D 331111 CDS YP_001463352.1 157158089 5590125 2256410..2257795 1 NC_009801.1 identified by similarity to GB:AAD39015.1; match to protein family HMM PF00171; propanediol utilization protein PduP 2257795 pduP 5590125 pduP Escherichia coli E24377A propanediol utilization protein PduP YP_001463352.1 2256410 D 331111 CDS YP_001463353.1 157158598 5586231 2257806..2258918 1 NC_009801.1 identified by similarity to GB:AAD39016.1; match to protein family HMM PF00465; propanediol utilization protein PduQ 2258918 pduQ 5586231 pduQ Escherichia coli E24377A propanediol utilization protein PduQ YP_001463353.1 2257806 D 331111 CDS YP_001463354.1 157159374 5586332 2258915..2260258 1 NC_009801.1 identified by similarity to GB:AAD39017.1; match to protein family HMM PF00037; match to protein family HMM PF01512; propanediol utilization protein PduS 2260258 pduS 5586332 pduS Escherichia coli E24377A propanediol utilization protein PduS YP_001463354.1 2258915 D 331111 CDS YP_001463355.1 157156513 5588886 2260261..2260815 1 NC_009801.1 identified by similarity to GB:AAV76807.1; match to protein family HMM PF00936; propanediol utilization protein PduT 2260815 pduT 5588886 pduT Escherichia coli E24377A propanediol utilization protein PduT YP_001463355.1 2260261 D 331111 CDS YP_001463356.1 157156977 5587214 2260815..2261165 1 NC_009801.1 identified by similarity to SP:P0A1D1; match to protein family HMM PF00936; propanediol utilization protein pduU 2261165 pduU 5587214 pduU Escherichia coli E24377A propanediol utilization protein pduU YP_001463356.1 2260815 D 331111 CDS YP_001463357.1 157157268 5588787 2261170..2261613 1 NC_009801.1 identified by similarity to SP:Q9XDM6; match to protein family HMM TIGR02528; propanediol utilization protein PduV 2261613 pduV 5588787 pduV Escherichia coli E24377A propanediol utilization protein PduV YP_001463357.1 2261170 D 331111 CDS YP_001463358.1 157156935 5587879 complement(2261714..2262043) 1 NC_009801.1 identified by match to protein family HMM PF04363; hypothetical protein 2262043 5587879 EcE24377A_2298 Escherichia coli E24377A hypothetical protein YP_001463358.1 2261714 R 331111 CDS YP_001463359.1 157159058 5587818 complement(2262215..2263273) 1 NC_009801.1 hypothetical protein 2263273 5587818 EcE24377A_2299 Escherichia coli E24377A hypothetical protein YP_001463359.1 2262215 R 331111 CDS YP_001463360.1 157157372 5590012 complement(2263472..2263945) 1 NC_009801.1 identified by similarity to GB:1JYH_A; match to protein family HMM PF06445; DNA gyrase inhibitor 2263945 gyrI 5590012 gyrI Escherichia coli E24377A DNA gyrase inhibitor YP_001463360.1 2263472 R 331111 CDS YP_001463361.1 157155424 5588879 complement(2264064..2265230) 1 NC_009801.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 2265230 dacD 5588879 dacD Escherichia coli E24377A D-alanyl-D-alanine carboxypeptidase YP_001463361.1 2264064 R 331111 CDS YP_001463362.1 157155858 5588345 2265419..2266846 1 NC_009801.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2266846 sbcB 5588345 sbcB Escherichia coli E24377A exonuclease I YP_001463362.1 2265419 D 331111 CDS YP_001463363.1 157159037 5588437 complement(2266889..2267116) 1 NC_009801.1 identified by match to protein family HMM PF01206; hypothetical protein 2267116 5588437 EcE24377A_2303 Escherichia coli E24377A hypothetical protein YP_001463363.1 2266889 R 331111 CDS YP_001463364.1 157159262 5587948 complement(2267130..2268179) 1 NC_009801.1 identified by match to protein family HMM PF04143; hypothetical protein 2268179 5587948 EcE24377A_2304 Escherichia coli E24377A hypothetical protein YP_001463364.1 2267130 R 331111 CDS YP_001463365.1 157156766 5587398 complement(2268367..2269725) 1 NC_009801.1 identified by match to protein family HMM PF00324; amino acid permease 2269725 yeeF 5587398 yeeF Escherichia coli E24377A amino acid permease YP_001463365.1 2268367 R 331111 CDS YP_001463366.1 157156076 5589664 complement(2269992..2270921) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2270921 5589664 EcE24377A_2306 Escherichia coli E24377A LysR family transcriptional regulator YP_001463366.1 2269992 R 331111 CDS YP_001463367.1 157155443 5590710 complement(2270967..2271791) 1 NC_009801.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; NAD dependent epimerase/dehydratase 2271791 5590710 EcE24377A_2307 Escherichia coli E24377A NAD dependent epimerase/dehydratase YP_001463367.1 2270967 R 331111 CDS YP_001463368.1 157154770 5588250 complement(2271874..2272128) 1 NC_009801.1 identified by similarity to SP:P69349; match to protein family HMM PF06769; match to protein family HMM TIGR02116; toxin YoeB 2272128 yoeB 5588250 yoeB Escherichia coli E24377A toxin YoeB YP_001463368.1 2271874 R 331111 CDS YP_001463369.1 157159460 5588467 complement(2272125..2272376) 1 NC_009801.1 Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM 2272376 yefM 5588467 yefM Escherichia coli E24377A antitoxin YefM YP_001463369.1 2272125 R 331111 CDS YP_001463370.1 157158646 5590174 2272855..2273754 1 NC_009801.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2273754 hisG 5590174 hisG Escherichia coli E24377A ATP phosphoribosyltransferase YP_001463370.1 2272855 D 331111 CDS YP_001463371.1 157158130 5589215 2273760..2275064 1 NC_009801.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2275064 hisD 5589215 hisD Escherichia coli E24377A histidinol dehydrogenase YP_001463371.1 2273760 D 331111 CDS YP_001463372.1 157156128 5586045 2275061..2276131 1 NC_009801.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2276131 hisC 5586045 hisC Escherichia coli E24377A histidinol-phosphate aminotransferase YP_001463372.1 2275061 D 331111 CDS YP_001463373.1 157155752 5586479 2276131..2277198 1 NC_009801.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2277198 hisB 5586479 hisB Escherichia coli E24377A imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_001463373.1 2276131 D 331111 CDS YP_001463374.1 157154822 5589951 2277198..2277788 1 NC_009801.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2277788 hisH 5589951 hisH Escherichia coli E24377A imidazole glycerol phosphate synthase subunit HisH YP_001463374.1 2277198 D 331111 CDS YP_001463375.1 157157485 5586927 2277788..2278525 1 NC_009801.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2278525 hisA 5586927 hisA Escherichia coli E24377A 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_001463375.1 2277788 D 331111 CDS YP_001463376.1 157159234 5588376 2278507..2279283 1 NC_009801.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2279283 hisF 5588376 hisF Escherichia coli E24377A imidazole glycerol phosphate synthase subunit HisF YP_001463376.1 2278507 D 331111 CDS YP_001463377.1 157156809 5588106 2279277..2279888 1 NC_009801.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2279888 hisIE 5588106 hisIE Escherichia coli E24377A bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase YP_001463377.1 2279277 D 331111 CDS YP_001463378.1 157156091 5587485 complement(2279985..2281019) 1 NC_009801.1 identified by similarity to SP:P76372; match to protein family HMM PF02706; chain length determinant protein 2281019 5587485 EcE24377A_2318 Escherichia coli E24377A chain length determinant protein YP_001463378.1 2279985 R 331111 CDS YP_001463379.1 157154758 5586037 complement(2281109..2282275) 1 NC_009801.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026; UDP-glucose 6-dehydrogenase 2282275 ugd 5586037 ugd Escherichia coli E24377A UDP-glucose 6-dehydrogenase YP_001463379.1 2281109 R 331111 CDS YP_001463380.1 157157026 5587627 complement(2282520..2283926) 1 NC_009801.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2283926 gnd 5587627 gnd Escherichia coli E24377A 6-phosphogluconate dehydrogenase YP_001463380.1 2282520 R 331111 CDS YP_001463381.1 157158578 5588011 complement(2284294..2285181) 1 NC_009801.1 hypothetical protein 2285181 5588011 EcE24377A_2321 Escherichia coli E24377A hypothetical protein YP_001463381.1 2284294 R 331111 CDS YP_001463382.1 157158956 5588319 complement(2285178..2286419) 1 NC_009801.1 hypothetical protein 2286419 5588319 EcE24377A_2322 Escherichia coli E24377A hypothetical protein YP_001463382.1 2285178 R 331111 CDS YP_001463383.1 157156116 5586307 complement(2286419..2287171) 1 NC_009801.1 identified by glimmer; hypothetical protein 2287171 5586307 EcE24377A_2323 Escherichia coli E24377A hypothetical protein YP_001463383.1 2286419 R 331111 CDS YP_001463384.1 157155425 5588814 complement(2287268..2288299) 1 NC_009801.1 identified by similarity to SP:Q04973; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993; VI polysaccharide biosynthesis protein vipB/tviC 2288299 vipB 5588814 vipB Escherichia coli E24377A VI polysaccharide biosynthesis protein vipB/tviC YP_001463384.1 2287268 R 331111 CDS YP_001463385.1 157155490 5588346 complement(2288314..2289588) 1 NC_009801.1 identified by similarity to SP:Q04972; match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026; VI polysaccharide biosynthesis protein VipA/tviB 2289588 vipA 5588346 vipA Escherichia coli E24377A VI polysaccharide biosynthesis protein VipA/tviB YP_001463385.1 2288314 R 331111 CDS YP_001463386.1 157154752 5588000 complement(2289707..2290720) 1 NC_009801.1 hypothetical protein 2290720 5588000 EcE24377A_2326 Escherichia coli E24377A hypothetical protein YP_001463386.1 2289707 R 331111 CDS YP_001463387.1 157156787 5587227 complement(2290736..2291479) 1 NC_009801.1 glycosyl transferase family protein 2291479 5587227 EcE24377A_2327 Escherichia coli E24377A glycosyl transferase family protein YP_001463387.1 2290736 R 331111 CDS YP_001463388.1 157156098 5588657 complement(2291476..2292456) 1 NC_009801.1 identified by match to protein family HMM PF00535; glycosyl transferase group 2 family protein 2292456 5588657 EcE24377A_2328 Escherichia coli E24377A glycosyl transferase group 2 family protein YP_001463388.1 2291476 R 331111 CDS YP_001463389.1 157158061 5588704 complement(2292512..2293060) 1 NC_009801.1 identified by match to protein family HMM PF00908; match to protein family HMM TIGR01221; dTDP-4-dehydrorhamnose 3,5-epimerase 2293060 rfbC 5588704 rfbC Escherichia coli E24377A dTDP-4-dehydrorhamnose 3,5-epimerase YP_001463389.1 2292512 R 331111 CDS YP_001463390.1 157157449 5586178 complement(2293065..2293943) 1 NC_009801.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidylyltransferase 2293943 rfbA1 5586178 rfbA1 Escherichia coli E24377A glucose-1-phosphate thymidylyltransferase YP_001463390.1 2293065 R 331111 CDS YP_001463391.1 157158895 5590247 complement(2294001..2294900) 1 NC_009801.1 with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose; dTDP-4-dehydrorhamnose reductase 2294900 rfbD 5590247 rfbD Escherichia coli E24377A dTDP-4-dehydrorhamnose reductase YP_001463391.1 2294001 R 331111 CDS YP_001463392.1 157154898 5589549 complement(2294900..2295985) 1 NC_009801.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose; dTDP-glucose-4,6-dehydratase 2295985 rfbB2 5589549 rfbB2 Escherichia coli E24377A dTDP-glucose-4,6-dehydratase YP_001463392.1 2294900 R 331111 CDS YP_001463393.1 157159205 5589629 complement(2296214..2296309) 1 NC_009801.1 identified by glimmer; hypothetical protein 2296309 5589629 EcE24377A_2333 Escherichia coli E24377A hypothetical protein YP_001463393.1 2296214 R 331111 CDS YP_001463394.1 157158858 5589189 complement(2296357..2297250) 1 NC_009801.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 2297250 galF 5589189 galF Escherichia coli E24377A UTP-glucose-1-phosphate uridylyltransferase YP_001463394.1 2296357 R 331111 CDS YP_001463395.1 157159381 5587086 complement(2297425..2298819) 1 NC_009801.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein 2298819 wcaM 5587086 wcaM Escherichia coli E24377A colanic acid biosynthesis protein YP_001463395.1 2297425 R 331111 CDS YP_001463396.1 157158914 5588258 complement(2298830..2300050) 1 NC_009801.1 identified by match to protein family HMM PF00534; colanic acid biosynthesis glycosyl transferase WcaL 2300050 wcaL 5588258 wcaL Escherichia coli E24377A colanic acid biosynthesis glycosyl transferase WcaL YP_001463396.1 2298830 R 331111 CDS YP_001463397.1 157156059 5589091 complement(2300047..2301327) 1 NC_009801.1 identified by match to protein family HMM PF04230; pyruvyl transferase 2301327 wcaK 5589091 wcaK Escherichia coli E24377A pyruvyl transferase YP_001463397.1 2300047 R 331111 CDS YP_001463398.1 157156699 5586801 complement(2301603..2303081) 1 NC_009801.1 identified by match to protein family HMM PF01943; colanic acid exporter 2303081 wzxC 5586801 wzxC Escherichia coli E24377A colanic acid exporter YP_001463398.1 2301603 R 331111 CDS YP_001463399.1 157157993 5589448 complement(2303083..2304477) 1 NC_009801.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase 2304477 5589448 EcE24377A_2339 Escherichia coli E24377A UDP-glucose lipid carrier transferase YP_001463399.1 2303083 R 331111 CDS YP_001463400.1 157155689 5590614 complement(2304532..2305902) 1 NC_009801.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphomannomutase 2305902 5590614 EcE24377A_2340 Escherichia coli E24377A phosphomannomutase YP_001463400.1 2304532 R 331111 CDS YP_001463401.1 157159024 5588765 2305928..2306086 1 NC_009801.1 identified by similarity to GB:AAN81029.1; hypothetical protein 2306086 5588765 EcE24377A_2341 Escherichia coli E24377A hypothetical protein YP_001463401.1 2305928 D 331111 CDS YP_001463402.1 157157123 5588393 complement(2306095..2307531) 1 NC_009801.1 identified by similarity to SP:P24174; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; mannose-1-phosphate guanylyltransferase 2307531 manC 5588393 manC Escherichia coli E24377A mannose-1-phosphate guanylyltransferase YP_001463402.1 2306095 R 331111 CDS YP_001463403.1 157157792 5590874 complement(2307534..2308757) 1 NC_009801.1 identified by match to protein family HMM PF00534; glycosyl transferase family protein 2308757 wcaI 5590874 wcaI Escherichia coli E24377A glycosyl transferase family protein YP_001463403.1 2307534 R 331111 CDS YP_001463404.1 157158307 5587808 complement(2308754..2309233) 1 NC_009801.1 identified by similarity to SP:P32056; match to protein family HMM PF00293; GDP-mannose mannosyl hydrolase 2309233 nudD 5587808 nudD Escherichia coli E24377A GDP-mannose mannosyl hydrolase YP_001463404.1 2308754 R 331111 CDS YP_001463405.1 157159074 5587395 complement(2309236..2310201) 1 NC_009801.1 identified by match to protein family HMM PF01370; match to protein family HMM PF04321; GDP-L-fucose synthetase 2310201 fcl 5587395 fcl Escherichia coli E24377A GDP-L-fucose synthetase YP_001463405.1 2309236 R 331111 CDS YP_001463406.1 157155501 5586851 complement(2310204..2311325) 1 NC_009801.1 identified by match to protein family HMM PF01370; match to protein family HMM TIGR01472; GDP-mannose 4,6-dehydratase 2311325 gmd 5586851 gmd Escherichia coli E24377A GDP-mannose 4,6-dehydratase YP_001463406.1 2310204 R 331111 CDS YP_001463407.1 157155740 5586110 complement(2311351..2311899) 1 NC_009801.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF 2311899 5586110 EcE24377A_2347 Escherichia coli E24377A colanic acid biosynthesis acetyltransferase WcaF YP_001463407.1 2311351 R 331111 CDS YP_001463408.1 157156247 5589707 complement(2311915..2312670) 1 NC_009801.1 identified by match to protein family HMM PF00535; glycosyl transferase family protein 2312670 wcaE 5589707 wcaE Escherichia coli E24377A glycosyl transferase family protein YP_001463408.1 2311915 R 331111 CDS YP_001463409.1 157157053 5587126 complement(2312681..2313898) 1 NC_009801.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein 2313898 wcaD 5587126 wcaD Escherichia coli E24377A colanic acid biosynthesis protein YP_001463409.1 2312681 R 331111 CDS YP_001463410.1 157158677 5587427 complement(2313873..2315090) 1 NC_009801.1 glycosyl transferase family protein 2315090 wcaC 5587427 wcaC Escherichia coli E24377A glycosyl transferase family protein YP_001463410.1 2313873 R 331111 CDS YP_001463411.1 157159359 5590285 complement(2315087..2315575) 1 NC_009801.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB 2315575 5590285 EcE24377A_2351 Escherichia coli E24377A colanic acid biosynthesis acetyltransferase WcaB YP_001463411.1 2315087 R 331111 CDS YP_001463412.1 157154928 5588480 complement(2315578..2316417) 1 NC_009801.1 identified by match to protein family HMM PF00535; glycosyl transferase family protein 2316417 wcaA 5588480 wcaA Escherichia coli E24377A glycosyl transferase family protein YP_001463412.1 2315578 R 331111 CDS YP_001463413.1 157155608 5589348 complement(2316595..2318757) 1 NC_009801.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase 2318757 wzc 5589348 wzc Escherichia coli E24377A tyrosine kinase YP_001463413.1 2316595 R 331111 CDS YP_001463414.1 157158537 5587936 complement(2318760..2319203) 1 NC_009801.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase 2319203 wzb 5587936 wzb Escherichia coli E24377A tyrosine phosphatase YP_001463414.1 2318760 R 331111 CDS YP_001463415.1 157158902 5587272 complement(2319209..2320348) 1 NC_009801.1 identified by match to protein family HMM PF02563; polysaccharide biosynthesis/export protein 2320348 5587272 EcE24377A_2355 Escherichia coli E24377A polysaccharide biosynthesis/export protein YP_001463415.1 2319209 R 331111 CDS YP_001463416.1 157155056 5589502 2321007..2322590 1 NC_009801.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741; TerC family/CBS/transporter associated domain-containing protein 2322590 5589502 EcE24377A_2356 Escherichia coli E24377A TerC family/CBS/transporter associated domain-containing protein YP_001463416.1 2321007 D 331111 CDS YP_001463417.1 157155494 5586372 complement(2322864..2324717) 1 NC_009801.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein 2324717 asmA 5586372 asmA Escherichia coli E24377A assembly protein YP_001463417.1 2322864 R 331111 CDS YP_001463418.1 157157097 5586633 complement(2324739..2325320) 1 NC_009801.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 2325320 dcd 5586633 dcd Escherichia coli E24377A deoxycytidine triphosphate deaminase YP_001463418.1 2324739 R 331111 CDS YP_001463419.1 157155008 5587552 complement(2325412..2326053) 1 NC_009801.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 2326053 udk 5587552 udk Escherichia coli E24377A uridine kinase YP_001463419.1 2325412 R 331111 CDS YP_001463420.1 157155968 5590152 2326371..2329688 1 NC_009801.1 contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; sensor protein 2329688 5590152 EcE24377A_2360 Escherichia coli E24377A sensor protein YP_001463420.1 2326371 D 331111 CDS YP_001463421.1 157157936 5590068 complement(2329727..2330584) 1 NC_009801.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase 2330584 alkA 5590068 alkA Escherichia coli E24377A 3-methyladenine DNA glycosylase YP_001463421.1 2329727 R 331111 CDS YP_001463422.1 157154954 5588627 2330718..2332070 1 NC_009801.1 chaperone 2332070 5588627 EcE24377A_2362 Escherichia coli E24377A chaperone YP_001463422.1 2330718 D 331111 CDS YP_001463423.1 157156242 5586046 complement(2332082..2334022) 1 NC_009801.1 hypothetical protein 2334022 5586046 EcE24377A_2363 Escherichia coli E24377A hypothetical protein YP_001463423.1 2332082 R 331111 CDS YP_001463424.1 157155826 5586243 complement(2334019..2334780) 1 NC_009801.1 identified by similarity to GB:AAP17498.1; hypothetical protein 2334780 5586243 EcE24377A_2364 Escherichia coli E24377A hypothetical protein YP_001463424.1 2334019 R 331111 CDS YP_001463425.1 157155169 5590105 complement(2334777..2335436) 1 NC_009801.1 identified by match to protein family HMM PF00092; von Willebrand factor A 2335436 5590105 EcE24377A_2365 Escherichia coli E24377A von Willebrand factor A YP_001463425.1 2334777 R 331111 CDS YP_001463426.1 157159391 5587477 2336652..2337899 1 NC_009801.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2337899 mdtA 5587477 mdtA Escherichia coli E24377A multidrug efflux system subunit MdtA YP_001463426.1 2336652 D 331111 CDS YP_001463427.1 157158287 5590006 2337899..2341021 1 NC_009801.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2341021 mdtB 5590006 mdtB Escherichia coli E24377A multidrug efflux system subunit MdtB YP_001463427.1 2337899 D 331111 CDS YP_001463428.1 157157887 5587177 2341022..2344099 1 NC_009801.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2344099 mdtC 5587177 mdtC Escherichia coli E24377A multidrug efflux system subunit MdtC YP_001463428.1 2341022 D 331111 CDS YP_001463429.1 157157401 5590634 2344100..2345515 1 NC_009801.1 identified by match to protein family HMM PF07690; multidrug efflux system protein MdtE 2345515 5590634 EcE24377A_2369 Escherichia coli E24377A multidrug efflux system protein MdtE YP_001463429.1 2344100 D 331111 CDS YP_001463430.1 157157885 5589156 2345512..2346915 1 NC_009801.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; signal transduction histidine-protein kinase BaeS 2346915 baeS 5589156 baeS Escherichia coli E24377A signal transduction histidine-protein kinase BaeS YP_001463430.1 2345512 D 331111 CDS YP_001463431.1 157155282 5585970 2346912..2347634 1 NC_009801.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2347634 baeR 5585970 baeR Escherichia coli E24377A DNA-binding transcriptional regulator BaeR YP_001463431.1 2346912 D 331111 CDS YP_001463432.1 157159209 5588843 2347825..2348157 1 NC_009801.1 identified by similarity to SP:Q8EAL4; similarity to GB:CAG67631.1; match to protein family HMM PF07411; hypothetical protein 2348157 5588843 EcE24377A_2372 Escherichia coli E24377A hypothetical protein YP_001463432.1 2347825 D 331111 CDS YP_001463433.1 157155938 5586626 2348366..2348662 1 NC_009801.1 identified by match to protein family HMM PF01402; match to protein family HMM PF03693; match to protein family HMM TIGR02606; CC2985 family addiction module antidote protein 2348662 5586626 EcE24377A_2373 Escherichia coli E24377A CC2985 family addiction module antidote protein YP_001463433.1 2348366 D 331111 CDS YP_001463434.1 157155871 5586374 2348664..2348960 1 NC_009801.1 identified by match to protein family HMM PF05016; RelE/ParE family plasmid stabilization system protein 2348960 5586374 EcE24377A_2374 Escherichia coli E24377A RelE/ParE family plasmid stabilization system protein YP_001463434.1 2348664 D 331111 CDS YP_001463435.1 157157728 5589262 2349063..2350424 1 NC_009801.1 identified by match to protein family HMM PF01136; U32 family peptidase 2350424 5589262 EcE24377A_2375 Escherichia coli E24377A U32 family peptidase YP_001463435.1 2349063 D 331111 CDS YP_001463436.1 157157198 5590776 complement(2350754..2351131) 1 NC_009801.1 identified by similarity to GB:ABB65576.1; hypothetical protein 2351131 5590776 EcE24377A_2376 Escherichia coli E24377A hypothetical protein YP_001463436.1 2350754 R 331111 CDS YP_001463437.1 157159052 5586923 2351477..2352376 1 NC_009801.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2352376 5586923 EcE24377A_2377 Escherichia coli E24377A lipid kinase YP_001463437.1 2351477 D 331111 CDS YP_001463438.1 157158546 5588849 complement(2352458..2353231) 1 NC_009801.1 identified by similarity to SP:P36930; match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; galactitol utilization operon repressor 2353231 gatR 5588849 gatR Escherichia coli E24377A galactitol utilization operon repressor YP_001463438.1 2352458 R 331111 CDS YP_001463439.1 157157813 5588829 complement(2353337..2354377) 1 NC_009801.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase 2354377 gatD 5588829 gatD Escherichia coli E24377A galactitol-1-phosphate dehydrogenase YP_001463439.1 2353337 R 331111 CDS YP_001463440.1 157158630 5587011 complement(2354425..2355780) 1 NC_009801.1 identified by match to protein family HMM PF03611; match to protein family HMM TIGR00827; PTS system galactitol-specific transporter subunit IIC 2355780 gatC 5587011 gatC Escherichia coli E24377A PTS system galactitol-specific transporter subunit IIC YP_001463440.1 2354425 R 331111 CDS YP_001463441.1 157156954 5589107 complement(2355784..2356068) 1 NC_009801.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB 2356068 gatB 5589107 gatB Escherichia coli E24377A PTS system galactitol-specific transporter subunit IIB YP_001463441.1 2355784 R 331111 CDS YP_001463442.1 157155146 5587605 complement(2356099..2356551) 1 NC_009801.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA 2356551 gatA 5587605 gatA Escherichia coli E24377A PTS system galactitol-specific transporter subunit IIA YP_001463442.1 2356099 R 331111 CDS YP_001463443.1 157156384 5589435 complement(2356561..2357823) 1 NC_009801.1 identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810; D-tagatose-bisphosphate aldolase non-catalytic subunit 2357823 5589435 EcE24377A_2383 Escherichia coli E24377A D-tagatose-bisphosphate aldolase non-catalytic subunit YP_001463443.1 2356561 R 331111 CDS YP_001463444.1 157156604 5587419 complement(2357852..2358706) 1 NC_009801.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 2358706 gatY 5587419 gatY Escherichia coli E24377A tagatose-bisphosphate aldolase YP_001463444.1 2357852 R 331111 CDS YP_001463445.1 157157113 5586555 complement(2359014..2360066) 1 NC_009801.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 2360066 fbaB 5586555 fbaB Escherichia coli E24377A fructose-bisphosphate aldolase YP_001463445.1 2359014 R 331111 CDS YP_001463446.1 157157737 5590547 2360323..2361600 1 NC_009801.1 identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889; nucleoside transporter 2361600 yegT 5590547 yegT Escherichia coli E24377A nucleoside transporter YP_001463446.1 2360323 D 331111 CDS YP_001463447.1 157158412 5590009 2361597..2362601 1 NC_009801.1 identified by match to protein family HMM PF03747; ADP-ribosylglycohydrolase 2362601 5590009 EcE24377A_2387 Escherichia coli E24377A ADP-ribosylglycohydrolase YP_001463447.1 2361597 D 331111 CDS YP_001463448.1 157156849 5586101 2362598..2363563 1 NC_009801.1 identified by match to protein family HMM PF00294; PfkB family kinase 2363563 5586101 EcE24377A_2389 Escherichia coli E24377A PfkB family kinase YP_001463448.1 2362598 D 331111 CDS YP_001463449.1 157159078 5586569 complement(2363537..2364283) 1 NC_009801.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM PF08279; GntR family transcriptional regulator 2364283 5586569 EcE24377A_2388 Escherichia coli E24377A GntR family transcriptional regulator YP_001463449.1 2363537 R 331111 CDS YP_001463450.1 157158602 5587983 complement(2364335..2365153) 1 NC_009801.1 identified by match to protein family HMM PF01183; glycosyl hydrolase 2365153 5587983 EcE24377A_2390 Escherichia coli E24377A glycosyl hydrolase YP_001463450.1 2364335 R 331111 CDS YP_001463451.1 157154867 5586968 complement(2365218..2366018) 1 NC_009801.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 2366018 thiD 5586968 thiD Escherichia coli E24377A phosphomethylpyrimidine kinase YP_001463451.1 2365218 R 331111 CDS YP_001463452.1 157155537 5590734 complement(2366015..2366803) 1 NC_009801.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 2366803 thiM 5590734 thiM Escherichia coli E24377A hydroxyethylthiazole kinase YP_001463452.1 2366015 R 331111 CDS YP_001463453.1 157155925 5589199 complement(2367026..2367298) 1 NC_009801.1 identified by similarity to SP:P64530; match to protein family HMM PF02583; transcriptional repressor RcnR 2367298 rcnR 5589199 rcnR Escherichia coli E24377A transcriptional repressor RcnR YP_001463453.1 2367026 R 331111 CDS YP_001463454.1 157158108 5586583 2368282..2368800 1 NC_009801.1 identified by similarity to GB:AAN81090.1; hypothetical protein 2368800 5586583 EcE24377A_2395 Escherichia coli E24377A hypothetical protein YP_001463454.1 2368282 D 331111 CDS YP_001463455.1 157158877 5590377 complement(2368882..2369916) 1 NC_009801.1 hypothetical protein 2369916 5590377 EcE24377A_2396 Escherichia coli E24377A hypothetical protein YP_001463455.1 2368882 R 331111 CDS YP_001463456.1 157159371 5590342 2369435..2369599 1 NC_009801.1 identified by glimmer; hypothetical protein 2369599 5590342 EcE24377A_2397 Escherichia coli E24377A hypothetical protein YP_001463456.1 2369435 D 331111 CDS YP_001463457.1 157157729 5589063 complement(2369930..2372410) 1 NC_009801.1 identified by match to protein family HMM PF00577; fimbrial usher protein 2372410 5589063 EcE24377A_2399 Escherichia coli E24377A fimbrial usher protein YP_001463457.1 2369930 R 331111 CDS YP_001463458.1 157156869 5590777 complement(2372426..2373100) 1 NC_009801.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; pilus assembly chaperone 2373100 5590777 EcE24377A_2400 Escherichia coli E24377A pilus assembly chaperone YP_001463458.1 2372426 R 331111 CDS YP_001463459.1 157156309 5590599 2372793..2372903 1 NC_009801.1 identified by glimmer; hypothetical protein 2372903 5590599 EcE24377A_2401 Escherichia coli E24377A hypothetical protein YP_001463459.1 2372793 D 331111 CDS YP_001463460.1 157158851 5586693 complement(2373181..2373723) 1 NC_009801.1 identified by match to protein family HMM PF00419; fimbrial protein 2373723 5586693 EcE24377A_2402 Escherichia coli E24377A fimbrial protein YP_001463460.1 2373181 R 331111 CDS YP_001463461.1 157155630 5586205 complement(2374560..2375669) 1 NC_009801.1 identified by similarity to SP:P0AF08; ATPase 2375669 5586205 EcE24377A_2403 Escherichia coli E24377A ATPase YP_001463461.1 2374560 R 331111 CDS YP_001463462.1 157157217 5588091 2375801..2377834 1 NC_009801.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2377834 metG 5588091 metG Escherichia coli E24377A methionyl-tRNA synthetase YP_001463462.1 2375801 D 331111 CDS YP_001463463.1 157159379 5590235 2377975..2381769 1 NC_009801.1 identified by similarity to SP:P33345; match to protein family HMM PF05406; molybdate metabolism regulator 2381769 molR 5590235 molR Escherichia coli E24377A molybdate metabolism regulator YP_001463463.1 2377975 D 331111 CDS YP_001463464.1 157158503 5590354 2386975..2388063 1 NC_009801.1 identified by match to protein family HMM PF07728; ATPase AAA 2388063 5590354 EcE24377A_2407 Escherichia coli E24377A ATPase AAA YP_001463464.1 2386975 D 331111 CDS YP_001463465.1 157155415 5588981 2388074..2390353 1 NC_009801.1 identified by similarity to GB:AAN81106.1; hypothetical protein 2390353 5588981 EcE24377A_2408 Escherichia coli E24377A hypothetical protein YP_001463465.1 2388074 D 331111 CDS YP_001463466.1 157156675 5590273 2390346..2391482 1 NC_009801.1 yehP; identified by match to protein family HMM PF05762; von Willebrand factor A 2391482 5590273 EcE24377A_2409 Escherichia coli E24377A von Willebrand factor A YP_001463466.1 2390346 D 331111 CDS YP_001463467.1 157158183 5590516 2391479..2393479 1 NC_009801.1 identified by match to protein family HMM PF04434; hypothetical protein 2393479 5590516 EcE24377A_2410 Escherichia coli E24377A hypothetical protein YP_001463467.1 2391479 D 331111 CDS YP_001463468.1 157155584 5590589 2393604..2394065 1 NC_009801.1 identified by match to protein family HMM PF06998; lipoprotein 2394065 5590589 EcE24377A_2411 Escherichia coli E24377A lipoprotein YP_001463468.1 2393604 D 331111 CDS YP_001463469.1 157154750 5590362 complement(2394106..2394576) 1 NC_009801.1 identified by match to protein family HMM PF07308; hypothetical protein 2394576 5590362 EcE24377A_2412 Escherichia coli E24377A hypothetical protein YP_001463469.1 2394106 R 331111 CDS YP_001463470.1 157159247 5587067 complement(2394623..2395342) 1 NC_009801.1 unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT 2395342 5587067 EcE24377A_2413 Escherichia coli E24377A two-component response-regulatory protein YehT YP_001463470.1 2394623 R 331111 CDS YP_001463471.1 157158456 5590880 complement(2395339..2397024) 1 NC_009801.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694; sensor histidine kinase 2397024 5590880 EcE24377A_2414 Escherichia coli E24377A sensor histidine kinase YP_001463471.1 2395339 R 331111 CDS YP_001463472.1 157158198 5587196 2397246..2397977 1 NC_009801.1 identified by similarity to SP:P33358; match to protein family HMM PF00376; transcriptional regulator MlrA 2397977 mlrA 5587196 mlrA Escherichia coli E24377A transcriptional regulator MlrA YP_001463472.1 2397246 D 331111 CDS YP_001463473.1 157156042 5586753 2398037..2398144 1 NC_009801.1 identified by similarity to GB:AAZ88835.1; hypothetical protein 2398144 5586753 EcE24377A_2417 Escherichia coli E24377A hypothetical protein YP_001463473.1 2398037 D 331111 CDS YP_001463474.1 157157695 5586039 complement(2398125..2398856) 1 NC_009801.1 identified by match to protein family HMM PF00528; quaternary amine ABC transporter permease 2398856 5586039 EcE24377A_2416 Escherichia coli E24377A quaternary amine ABC transporter permease YP_001463474.1 2398125 R 331111 CDS YP_001463475.1 157158701 5587114 complement(2398861..2399787) 1 NC_009801.1 identified by match to protein family HMM PF00005; quaternary amine ABC transporter ATP-binding protein 2399787 5587114 EcE24377A_2418 Escherichia coli E24377A quaternary amine ABC transporter ATP-binding protein YP_001463475.1 2398861 R 331111 CDS YP_001463476.1 157156192 5589601 complement(2399780..2400937) 1 NC_009801.1 identified by match to protein family HMM PF00528; quaternary amine ABC transporter permease 2400937 5589601 EcE24377A_2419 Escherichia coli E24377A quaternary amine ABC transporter permease YP_001463476.1 2399780 R 331111 CDS YP_001463477.1 157156757 5588670 complement(2400944..2401861) 1 NC_009801.1 identified by match to protein family HMM PF04069; quaternary amine ABC transporter substrate-binding protein 2401861 5588670 EcE24377A_2420 Escherichia coli E24377A quaternary amine ABC transporter substrate-binding protein YP_001463477.1 2400944 R 331111 CDS YP_001463478.1 157154880 5590165 complement(2402113..2404410) 1 NC_009801.1 identified by similarity to SP:P33363; match to protein family HMM PF00933; match to protein family HMM PF01915; beta-glucosidase, periplasmic 2404410 bglX 5590165 bglX Escherichia coli E24377A beta-glucosidase, periplasmic YP_001463478.1 2402113 R 331111 CDS YP_001463479.1 157155391 5588330 2404411..2404569 1 NC_009801.1 identified by glimmer; hypothetical protein 2404569 5588330 EcE24377A_2422 Escherichia coli E24377A hypothetical protein YP_001463479.1 2404411 D 331111 CDS YP_001463480.1 157158318 5588735 2404606..2406321 1 NC_009801.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2406321 dld 5588735 dld Escherichia coli E24377A D-lactate dehydrogenase YP_001463480.1 2404606 D 331111 CDS YP_001463481.1 157159398 5587460 complement(2406359..2407300) 1 NC_009801.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 2407300 pbpG 5587460 pbpG Escherichia coli E24377A D-alanyl-D-alanine endopeptidase YP_001463481.1 2406359 R 331111 CDS YP_001463482.1 157158829 5590060 complement(2407465..2408052) 1 NC_009801.1 identified by match to protein family HMM PF06930; hypothetical protein 2408052 5590060 EcE24377A_2425 Escherichia coli E24377A hypothetical protein YP_001463482.1 2407465 R 331111 CDS YP_001463483.1 157159352 5586263 2408222..2408800 1 NC_009801.1 identified by similarity to SP:P33366; match to protein family HMM PF09335; hypothetical protein 2408800 5586263 EcE24377A_2426 Escherichia coli E24377A hypothetical protein YP_001463483.1 2408222 D 331111 CDS YP_001463484.1 157157527 5588455 complement(2408930..2409691) 1 NC_009801.1 identified by match to protein family HMM PF00106; acetoin dehydrogenase 2409691 5588455 EcE24377A_2427 Escherichia coli E24377A acetoin dehydrogenase YP_001463484.1 2408930 R 331111 CDS YP_001463485.1 157159177 5589555 complement(2409744..2411180) 1 NC_009801.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ 2411180 5589555 EcE24377A_2428 Escherichia coli E24377A multidrug resistance outer membrane protein MdtQ YP_001463485.1 2409744 R 331111 CDS YP_001463486.1 157157351 5590349 complement(2411860..2412807) 1 NC_009801.1 identified by similarity to SP:P33371; match to protein family HMM PF01207; tRNA-dihydrouridine synthase C 2412807 dusC 5590349 dusC Escherichia coli E24377A tRNA-dihydrouridine synthase C YP_001463486.1 2411860 R 331111 CDS YP_001463487.1 157156465 5590059 complement(2414076..2414720) 1 NC_009801.1 identified by match to protein family HMM PF02798; match to protein family HMM TIGR01262; maleylacetoacetate isomerase 2414720 maiA 5590059 maiA Escherichia coli E24377A maleylacetoacetate isomerase YP_001463487.1 2414076 R 331111 CDS YP_001463488.1 157155625 5586070 complement(2414729..2415430) 1 NC_009801.1 identified by match to protein family HMM PF01557; fumarylacetoacetate hydrolase 2415430 5586070 EcE24377A_2432 Escherichia coli E24377A fumarylacetoacetate hydrolase YP_001463488.1 2414729 R 331111 CDS YP_001463489.1 157155116 5590259 complement(2415446..2416474) 1 NC_009801.1 identified by similarity to GB:CAA12267.1; match to protein family HMM PF07883; match to protein family HMM TIGR02272; gentisate 1,2-dioxygenase 2416474 gtdA 5590259 gtdA Escherichia coli E24377A gentisate 1,2-dioxygenase YP_001463489.1 2415446 R 331111 CDS YP_001463490.1 157159067 5589206 complement(2416486..2417844) 1 NC_009801.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator transporter 2417844 5589206 EcE24377A_2434 Escherichia coli E24377A major facilitator transporter YP_001463490.1 2416486 R 331111 CDS YP_001463491.1 157158564 5590519 2417923..2418879 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2418879 5590519 EcE24377A_2435 Escherichia coli E24377A LysR family transcriptional regulator YP_001463491.1 2417923 D 331111 CDS YP_001463492.1 157156691 5586300 2419010..2419408 1 NC_009801.1 identified by match to protein family HMM PF03788; hypothetical protein 2419408 5586300 EcE24377A_2436 Escherichia coli E24377A hypothetical protein YP_001463492.1 2419010 D 331111 CDS YP_001463493.1 157156463 5586808 2419405..2420100 1 NC_009801.1 identified by match to protein family HMM PF04172; match to protein family HMM TIGR00659; hypothetical protein 2420100 5586808 EcE24377A_2437 Escherichia coli E24377A hypothetical protein YP_001463493.1 2419405 D 331111 CDS YP_001463494.1 157156119 5585998 2420230..2421114 1 NC_009801.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2421114 cdd 5585998 cdd Escherichia coli E24377A cytidine deaminase YP_001463494.1 2420230 D 331111 CDS YP_001463495.1 157156428 5587811 2421264..2421983 1 NC_009801.1 identified by similarity to SP:P0AFY5; match to protein family HMM PF02698; hypothetical protein 2421983 sanA 5587811 sanA Escherichia coli E24377A hypothetical protein YP_001463495.1 2421264 D 331111 CDS YP_001463496.1 157157929 5586711 2421986..2422225 1 NC_009801.1 identified by similarity to SP:P64539; hypothetical protein 2422225 5586711 EcE24377A_2440 Escherichia coli E24377A hypothetical protein YP_001463496.1 2421986 D 331111 CDS YP_001463497.1 157157365 5586014 2422544..2423782 1 NC_009801.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 2423782 5586014 EcE24377A_2441 Escherichia coli E24377A oxidoreductase YP_001463497.1 2422544 D 331111 CDS YP_001463498.1 157158894 5590585 2423776..2425011 1 NC_009801.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2425011 5590585 EcE24377A_2442 Escherichia coli E24377A dihydropyrimidine dehydrogenase YP_001463498.1 2423776 D 331111 CDS YP_001463499.1 157158394 5589548 complement(2425082..2426092) 1 NC_009801.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein 2426092 mglC 5589548 mglC Escherichia coli E24377A beta-methylgalactoside transporter inner membrane protein YP_001463499.1 2425082 R 331111 CDS YP_001463500.1 157155323 5589759 complement(2426108..2427628) 1 NC_009801.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 2427628 mglA 5589759 mglA Escherichia coli E24377A galactose/methyl galaxtoside transporter ATP-binding protein YP_001463500.1 2426108 R 331111 CDS YP_001463501.1 157157007 5589862 complement(2427689..2428687) 1 NC_009801.1 identified by similarity to SP:P0AEE5; match to protein family HMM PF00532; galactose ABC transporter periplasmic galactose-binding protein 2428687 mglB 5589862 mglB Escherichia coli E24377A galactose ABC transporter periplasmic galactose-binding protein YP_001463501.1 2427689 R 331111 CDS YP_001463502.1 157156713 5586644 complement(2428967..2430007) 1 NC_009801.1 negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS 2430007 galS 5586644 galS Escherichia coli E24377A DNA-binding transcriptional regulator GalS YP_001463502.1 2428967 R 331111 CDS YP_001463503.1 157158989 5589470 2429997..2430200 1 NC_009801.1 identified by glimmer; hypothetical protein 2430200 5589470 EcE24377A_2448 Escherichia coli E24377A hypothetical protein YP_001463503.1 2429997 D 331111 CDS YP_001463504.1 157158849 5586992 complement(2430149..2431306) 1 NC_009801.1 identified by match to protein family HMM PF04171; match to protein family HMM PF04235; hypothetical protein 2431306 5586992 EcE24377A_2447 Escherichia coli E24377A hypothetical protein YP_001463504.1 2430149 R 331111 CDS YP_001463505.1 157157114 5587776 complement(2431323..2431991) 1 NC_009801.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 2431991 folE 5587776 folE Escherichia coli E24377A GTP cyclohydrolase I YP_001463505.1 2431323 R 331111 CDS YP_001463506.1 157157975 5590639 2432249..2433085 1 NC_009801.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821; S-formylglutathione hydrolase 2433085 fghA2 5590639 fghA2 Escherichia coli E24377A S-formylglutathione hydrolase YP_001463506.1 2432249 D 331111 CDS YP_001463507.1 157155983 5587524 complement(2433117..2435108) 1 NC_009801.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor 2435108 cirA 5587524 cirA Escherichia coli E24377A colicin I receptor YP_001463507.1 2433117 R 331111 CDS YP_001463508.1 157156370 5586763 complement(2435101..2435304) 1 NC_009801.1 identified by glimmer; hypothetical protein 2435304 5586763 EcE24377A_2452 Escherichia coli E24377A hypothetical protein YP_001463508.1 2435101 R 331111 CDS YP_001463509.1 157154924 5586468 complement(2435401..2436870) 1 NC_009801.1 identified by match to protein family HMM PF00324; lysine transporter 2436870 lysP 5586468 lysP Escherichia coli E24377A lysine transporter YP_001463509.1 2435401 R 331111 CDS YP_001463510.1 157155187 5588526 complement(2437075..2437956) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator 2437956 5588526 EcE24377A_2454 Escherichia coli E24377A DNA-binding transcriptional regulator YP_001463510.1 2437075 R 331111 CDS YP_001463511.1 157155873 5590098 2438055..2439104 1 NC_009801.1 identified by match to protein family HMM PF03601; match to protein family HMM TIGR00698; hypothetical protein 2439104 5590098 EcE24377A_2455 Escherichia coli E24377A hypothetical protein YP_001463511.1 2438055 D 331111 CDS YP_001463512.1 157158335 5589264 2439178..2440035 1 NC_009801.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2440035 nfo 5589264 nfo Escherichia coli E24377A endonuclease IV YP_001463512.1 2439178 D 331111 CDS YP_001463513.1 157158606 5588385 complement(2441183..2442433) 1 NC_009801.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804; NupC family nucleoside transporter 2442433 5588385 EcE24377A_2458 Escherichia coli E24377A NupC family nucleoside transporter YP_001463513.1 2441183 R 331111 CDS YP_001463514.1 157155576 5586900 complement(2442533..2443474) 1 NC_009801.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 2443474 rihB 5586900 rihB Escherichia coli E24377A ribonucleoside hydrolase 2 YP_001463514.1 2442533 R 331111 CDS YP_001463515.1 157154911 5588427 2443643..2444302 1 NC_009801.1 activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2444302 nsr 5588427 nsr Escherichia coli E24377A DNA-binding transcriptional activator YeiL YP_001463515.1 2443643 D 331111 CDS YP_001463516.1 157156640 5587252 complement(2444373..2445623) 1 NC_009801.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804; NupC family nucleoside transporter 2445623 yeiM 5587252 yeiM Escherichia coli E24377A NupC family nucleoside transporter YP_001463516.1 2444373 R 331111 CDS YP_001463517.1 157155991 5587033 complement(2445717..2446655) 1 NC_009801.1 identified by match to protein family HMM PF04227; indigoidine synthase A like protein 2446655 5587033 EcE24377A_2462 Escherichia coli E24377A indigoidine synthase A like protein YP_001463517.1 2445717 R 331111 CDS YP_001463518.1 157156425 5589969 complement(2446643..2447584) 1 NC_009801.1 identified by match to protein family HMM PF00294; hypothetical protein 2447584 5589969 EcE24377A_2463 Escherichia coli E24377A hypothetical protein YP_001463518.1 2446643 R 331111 CDS YP_001463519.1 157157802 5586727 complement(2448008..2449699) 1 NC_009801.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC 2449699 fruA 5586727 fruA Escherichia coli E24377A PTS system fructose-specific transporter subunit IIBC YP_001463519.1 2448008 R 331111 CDS YP_001463520.1 157157517 5590063 complement(2449716..2450654) 1 NC_009801.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 2450654 fruK 5590063 fruK Escherichia coli E24377A 1-phosphofructokinase YP_001463520.1 2449716 R 331111 CDS YP_001463521.1 157159448 5589819 complement(2450654..2451784) 1 NC_009801.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein 2451784 fruB 5589819 fruB Escherichia coli E24377A bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein YP_001463521.1 2450654 R 331111 CDS YP_001463522.1 157155219 5588629 2451950..2452081 1 NC_009801.1 identified by glimmer; hypothetical protein 2452081 5588629 EcE24377A_2467 Escherichia coli E24377A hypothetical protein YP_001463522.1 2451950 D 331111 CDS YP_001463523.1 157155722 5588835 2452152..2453333 1 NC_009801.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00899; sugar efflux transporter B 2453333 setB 5588835 setB Escherichia coli E24377A sugar efflux transporter B YP_001463523.1 2452152 D 331111 CDS YP_001463524.1 157156343 5586383 2453484..2454311 1 NC_009801.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2454311 5586383 EcE24377A_2469 Escherichia coli E24377A elongation factor P YP_001463524.1 2453484 D 331111 CDS YP_001463525.1 157156832 5586804 2454534..2456000 1 NC_009801.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol dehydrogenase 2456000 5586804 EcE24377A_2470 Escherichia coli E24377A mannitol dehydrogenase YP_001463525.1 2454534 D 331111 CDS YP_001463526.1 157157928 5586413 2456118..2457104 1 NC_009801.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683; CobW/P47K family protein 2457104 5586413 EcE24377A_2471 Escherichia coli E24377A CobW/P47K family protein YP_001463526.1 2456118 D 331111 CDS YP_001463527.1 157158442 5587469 2457143..2457856 1 NC_009801.1 identified by match to protein family HMM PF01569; PAP2 family protein 2457856 5587469 EcE24377A_2472 Escherichia coli E24377A PAP2 family protein YP_001463527.1 2457143 D 331111 CDS YP_001463528.1 157156071 5588397 2458268..2458834 1 NC_009801.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 2458834 spr 5588397 spr Escherichia coli E24377A outer membrane lipoprotein YP_001463528.1 2458268 D 331111 CDS YP_001463529.1 157155463 5588297 2459015..2460571 1 NC_009801.1 identified by similarity to SP:P76446; match to protein family HMM PF00563; hypothetical protein 2460571 5588297 EcE24377A_2474 Escherichia coli E24377A hypothetical protein YP_001463529.1 2459015 D 331111 CDS YP_001463530.1 157157339 5587442 2460653..2462467 1 NC_009801.1 identified by match to protein family HMM PF00496; ABC transporter periplasmic solute-binding protein 2462467 5587442 EcE24377A_2475 Escherichia coli E24377A ABC transporter periplasmic solute-binding protein YP_001463530.1 2460653 D 331111 CDS YP_001463531.1 157156772 5590651 2462468..2463562 1 NC_009801.1 identified by match to protein family HMM PF00528; ABC transporter permease 2463562 5590651 EcE24377A_2476 Escherichia coli E24377A ABC transporter permease YP_001463531.1 2462468 D 331111 CDS YP_001463532.1 157158803 5589152 2463562..2464587 1 NC_009801.1 identified by match to protein family HMM PF00528; ABC transporter permease 2464587 5589152 EcE24377A_2477 Escherichia coli E24377A ABC transporter permease YP_001463532.1 2463562 D 331111 CDS YP_001463533.1 157155364 5589243 2464589..2466178 1 NC_009801.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2466178 5589243 EcE24377A_2478 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001463533.1 2464589 D 331111 CDS YP_001463534.1 157156668 5590065 complement(2466182..2466526) 1 NC_009801.1 identified by similarity to SP:P0AD23; hypothetical protein 2466526 5590065 EcE24377A_2479 Escherichia coli E24377A hypothetical protein YP_001463534.1 2466182 R 331111 CDS YP_001463535.1 157158188 5588600 complement(2466859..2468049) 1 NC_009801.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein 2468049 bcr 5588600 bcr Escherichia coli E24377A bicyclomycin/multidrug efflux system protein YP_001463535.1 2466859 R 331111 CDS YP_001463536.1 157155587 5589045 complement(2468077..2468772) 1 NC_009801.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A 2468772 rsuA 5589045 rsuA Escherichia coli E24377A 16S rRNA pseudouridylate synthase A YP_001463536.1 2468077 R 331111 CDS YP_001463537.1 157154738 5589781 2468921..2470681 1 NC_009801.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851; helicase 2470681 5589781 EcE24377A_2482 Escherichia coli E24377A helicase YP_001463537.1 2468921 D 331111 CDS YP_001463538.1 157158450 5588838 2470806..2471090 1 NC_009801.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2471090 rplY 5588838 rplY Escherichia coli E24377A 50S ribosomal protein L25 YP_001463538.1 2470806 D 331111 CDS YP_001463539.1 157158201 5587178 complement(2471229..2472236) 1 NC_009801.1 identified by similarity to SP:P33920; match to protein family HMM PF04245; nucleoid-associated protein NdpA 2472236 ndpA 5587178 ndpA Escherichia coli E24377A nucleoid-associated protein NdpA YP_001463539.1 2471229 R 331111 CDS YP_001463540.1 157158345 5587342 complement(2472281..2472400) 1 NC_009801.1 identified by glimmer; hypothetical protein 2472400 5587342 EcE24377A_2485 Escherichia coli E24377A hypothetical protein YP_001463540.1 2472281 R 331111 CDS YP_001463541.1 157156880 5589139 2472418..2472645 1 NC_009801.1 identified by match to protein family HMM PF07208; hypothetical protein 2472645 5589139 EcE24377A_2486 Escherichia coli E24377A hypothetical protein YP_001463541.1 2472418 D 331111 CDS YP_001463542.1 157155141 5589803 2472665..2474425 1 NC_009801.1 identified by match to protein family HMM PF00884; sulfatase 2474425 5589803 EcE24377A_2487 Escherichia coli E24377A sulfatase YP_001463542.1 2472665 D 331111 CDS YP_001463543.1 157158735 5590864 2477387..2477482 1 NC_009801.1 identified by glimmer; hypothetical protein 2477482 5590864 EcE24377A_2491 Escherichia coli E24377A hypothetical protein YP_001463543.1 2477387 D 331111 CDS YP_001463544.1 157156289 5585914 2477591..2478238 1 NC_009801.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2478238 narP 5585914 narP Escherichia coli E24377A transcriptional regulator NarP YP_001463544.1 2477591 D 331111 CDS YP_001463545.1 157156945 5588966 complement(2478273..2479325) 1 NC_009801.1 identified by match to protein family HMM PF03918; cytochrome c-type biogenesis family protein 2479325 5588966 EcE24377A_2493 Escherichia coli E24377A cytochrome c-type biogenesis family protein YP_001463545.1 2478273 R 331111 CDS YP_001463546.1 157157963 5587530 complement(2479322..2479879) 1 NC_009801.1 identified by similarity to SP:P0AA86; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR00385; thiol:disulfide interchange protein DsbE 2479879 dsbE 5587530 dsbE Escherichia coli E24377A thiol:disulfide interchange protein DsbE YP_001463546.1 2479322 R 331111 CDS YP_001463547.1 157158675 5586013 complement(2479876..2481819) 1 NC_009801.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR00353; cytochrome c-type biogenesis protein CcmF 2481819 ccmF 5586013 ccmF Escherichia coli E24377A cytochrome c-type biogenesis protein CcmF YP_001463547.1 2479876 R 331111 CDS YP_001463548.1 157158146 5586667 complement(2481816..2482295) 1 NC_009801.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 2482295 ccmE 5586667 ccmE Escherichia coli E24377A cytochrome c-type biogenesis protein CcmE YP_001463548.1 2481816 R 331111 CDS YP_001463549.1 157157647 5590785 complement(2482292..2482501) 1 NC_009801.1 identified by match to protein family HMM PF04995; match to protein family HMM TIGR03141; heme exporter protein D 2482501 ccmD 5590785 ccmD Escherichia coli E24377A heme exporter protein D YP_001463549.1 2482292 R 331111 CDS YP_001463550.1 157155253 5587380 complement(2482498..2483235) 1 NC_009801.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR01191; heme exporter protein C 2483235 ccmC 5587380 ccmC Escherichia coli E24377A heme exporter protein C YP_001463550.1 2482498 R 331111 CDS YP_001463551.1 157155955 5589368 complement(2483277..2483939) 1 NC_009801.1 identified by match to protein family HMM PF03379; match to protein family HMM TIGR01190; heme exporter protein CcmB 2483939 ccmB 5589368 ccmB Escherichia coli E24377A heme exporter protein CcmB YP_001463551.1 2483277 R 331111 CDS YP_001463552.1 157155394 5587127 complement(2483936..2484553) 1 NC_009801.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 2484553 ccmA 5587127 ccmA Escherichia coli E24377A cytochrome c biogenesis protein CcmA YP_001463552.1 2483936 R 331111 CDS YP_001463553.1 157154917 5588581 complement(2484572..2485174) 1 NC_009801.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC 2485174 napC 5588581 napC Escherichia coli E24377A cytochrome c-type protein NapC YP_001463553.1 2484572 R 331111 CDS YP_001463554.1 157155939 5590317 complement(2485184..2485633) 1 NC_009801.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit 2485633 napB 5590317 napB Escherichia coli E24377A citrate reductase cytochrome c-type subunit YP_001463554.1 2485184 R 331111 CDS YP_001463555.1 157157831 5586375 complement(2485630..2486493) 1 NC_009801.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 2486493 napH 5586375 napH Escherichia coli E24377A quinol dehydrogenase membrane component YP_001463555.1 2485630 R 331111 CDS YP_001463556.1 157154989 5588432 complement(2486480..2487175) 1 NC_009801.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 2487175 napG 5588432 napG Escherichia coli E24377A quinol dehydrogenase periplasmic component YP_001463556.1 2486480 R 331111 CDS YP_001463557.1 157155597 5586430 complement(2487182..2489668) 1 NC_009801.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 2489668 napA 5586430 napA Escherichia coli E24377A nitrate reductase catalytic subunit YP_001463557.1 2487182 R 331111 CDS YP_001463558.1 157157310 5587190 complement(2489665..2489928) 1 NC_009801.1 identified by match to protein family HMM PF03927; assembly protein for periplasmic nitrate reductase 2489928 napD 5587190 napD Escherichia coli E24377A assembly protein for periplasmic nitrate reductase YP_001463558.1 2489665 R 331111 CDS YP_001463559.1 157159007 5585933 complement(2489918..2490412) 1 NC_009801.1 Predicted role in electron transfer to the periplasmic nitrate reductase NapA.; ferredoxin-type protein 2490412 napF 5585933 napF Escherichia coli E24377A ferredoxin-type protein YP_001463559.1 2489918 R 331111 CDS YP_001463560.1 157157746 5586874 2490820..2491308 1 NC_009801.1 serine protease inhibitor, inhibits trypsin and other proteases; ecotin 2491308 eco 5586874 eco Escherichia coli E24377A ecotin YP_001463560.1 2490820 D 331111 CDS YP_001463561.1 157157678 5588173 complement(2491457..2493103) 1 NC_009801.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 2493103 mqo 5588173 mqo Escherichia coli E24377A malate:quinone oxidoreductase YP_001463561.1 2491457 R 331111 CDS YP_001463562.1 157157028 5586113 complement(2493321..2494964) 1 NC_009801.1 efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane protein/ATP-binding component 2494964 5586113 EcE24377A_2510 Escherichia coli E24377A multidrug transporter membrane protein/ATP-binding component YP_001463562.1 2493321 R 331111 CDS YP_001463563.1 157156371 5589150 complement(2495040..2495690) 1 NC_009801.1 identified by similarity to SP:P05050; match to protein family HMM PF03171; match to protein family HMM TIGR00568; alkylated DNA repair protein AlkB 2495690 alkB 5589150 alkB Escherichia coli E24377A alkylated DNA repair protein AlkB YP_001463563.1 2495040 R 331111 CDS YP_001463564.1 157156573 5586469 complement(2495690..2496754) 1 NC_009801.1 identified by similarity to SP:P06134; match to protein family HMM PF00165; match to protein family HMM PF01035; match to protein family HMM PF02805; match to protein family HMM PF02870; match to protein family HMM TIGR00589; regulatory protein Ada 2496754 ada 5586469 ada Escherichia coli E24377A regulatory protein Ada YP_001463564.1 2495690 R 331111 CDS YP_001463565.1 157156220 5588074 complement(2496828..2497883) 1 NC_009801.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE 2497883 apbE 5588074 apbE Escherichia coli E24377A thiamine biosynthesis lipoprotein ApbE YP_001463565.1 2496828 R 331111 CDS YP_001463566.1 157157896 5587201 complement(2497995..2499086) 1 NC_009801.1 allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C 2499086 ompC 5587201 ompC Escherichia coli E24377A outer membrane porin protein C YP_001463566.1 2497995 R 331111 CDS YP_001463567.1 157154810 5588055 2499825..2502497 1 NC_009801.1 identified by match to protein family HMM PF01627; match to protein family HMM PF02518; phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2502497 yojN 5588055 yojN Escherichia coli E24377A phosphotransfer intermediate protein in two-component regulatory system with RcsBC YP_001463567.1 2499825 D 331111 CDS YP_001463568.1 157155457 5587582 2502514..2503164 1 NC_009801.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2503164 rcsB 5587582 rcsB Escherichia coli E24377A transcriptional regulator RcsB YP_001463568.1 2502514 D 331111 CDS YP_001463569.1 157156212 5590740 complement(2503161..2503262) 1 NC_009801.1 identified by glimmer; hypothetical protein 2503262 5590740 EcE24377A_2516 Escherichia coli E24377A hypothetical protein YP_001463569.1 2503161 R 331111 CDS YP_001463570.1 157156685 5587338 2503193..2503288 1 NC_009801.1 identified by glimmer; hypothetical protein 2503288 5587338 EcE24377A_2518 Escherichia coli E24377A hypothetical protein YP_001463570.1 2503193 D 331111 CDS YP_001463571.1 157154824 5586692 complement(2503364..2506213) 1 NC_009801.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518; hybrid sensory kinase in two-component regulatory system with RcsB and YojN 2506213 rcsC 5586692 rcsC Escherichia coli E24377A hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_001463571.1 2503364 R 331111 CDS YP_001463572.1 157155592 5586662 2506383..2506478 1 NC_009801.1 identified by glimmer; hypothetical protein 2506478 5586662 EcE24377A_2520 Escherichia coli E24377A hypothetical protein YP_001463572.1 2506383 D 331111 CDS YP_001463573.1 157158749 5586950 complement(2506488..2507264) 1 NC_009801.1 identified by similarity to GB:AAG07875.1; hypothetical protein 2507264 5586950 EcE24377A_2521 Escherichia coli E24377A hypothetical protein YP_001463573.1 2506488 R 331111 CDS YP_001463574.1 157158399 5589522 complement(2507269..2508918) 1 NC_009801.1 identified by similarity to GB:AAZ88932.1; hypothetical protein 2508918 5589522 EcE24377A_2522 Escherichia coli E24377A hypothetical protein YP_001463574.1 2507269 R 331111 CDS YP_001463575.1 157157431 5590239 complement(2508919..2513433) 1 NC_009801.1 identified by match to protein family HMM PF01835; match to protein family HMM PF07703; alpha-2-macroglobulin 2513433 5590239 EcE24377A_2523 Escherichia coli E24377A alpha-2-macroglobulin YP_001463575.1 2508919 R 331111 CDS YP_001463576.2 229220663 5589789 complement(2513457..2514080) 1 NC_009801.1 identified by match to protein family HMM PF06672; hypothetical protein 2514080 5589789 EcE24377A_2524 Escherichia coli E24377A hypothetical protein YP_001463576.2 2513457 R 331111 CDS YP_001463577.1 157158702 5589940 complement(2514077..2515765) 1 NC_009801.1 identified by similarity to SP:P17994; hypothetical protein 2515765 5589940 EcE24377A_2525 Escherichia coli E24377A hypothetical protein YP_001463577.1 2514077 R 331111 CDS YP_001463578.1 157154912 5589602 complement(2515914..2518541) 1 NC_009801.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 2518541 gyrA 5589602 gyrA Escherichia coli E24377A DNA gyrase subunit A YP_001463578.1 2515914 R 331111 CDS YP_001463579.1 157154839 5587253 2518688..2519410 1 NC_009801.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2519410 ubiG 5587253 ubiG Escherichia coli E24377A 3-demethylubiquinone-9 3-methyltransferase YP_001463579.1 2518688 D 331111 CDS YP_001463580.1 157155352 5585919 complement(2519471..2523229) 1 NC_009801.1 yfaL; identified by match to protein family HMM PF02415; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01376; match to protein family HMM TIGR01414; match to protein family HMM TIGR02601; adhesin 2523229 5585919 EcE24377A_2528 Escherichia coli E24377A adhesin YP_001463580.1 2519471 R 331111 CDS YP_001463581.1 157158041 5589998 2522981..2523079 1 NC_009801.1 identified by glimmer; hypothetical protein 2523079 5589998 EcE24377A_2529 Escherichia coli E24377A hypothetical protein YP_001463581.1 2522981 D 331111 CDS YP_001463582.1 157158872 5589444 2523590..2523682 1 NC_009801.1 identified by glimmer; hypothetical protein 2523682 5589444 EcE24377A_2530 Escherichia coli E24377A hypothetical protein YP_001463582.1 2523590 D 331111 CDS YP_001463583.1 157156706 5587452 2523925..2526210 1 NC_009801.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2526210 nrdA 5587452 nrdA Escherichia coli E24377A ribonucleotide-diphosphate reductase subunit alpha YP_001463583.1 2523925 D 331111 CDS YP_001463584.1 157157492 5589922 2526299..2527429 1 NC_009801.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2527429 nrdB 5589922 nrdB Escherichia coli E24377A ribonucleotide-diphosphate reductase subunit beta YP_001463584.1 2526299 D 331111 CDS YP_001463585.1 157155326 5586251 2527429..2527683 1 NC_009801.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 2527683 5586251 EcE24377A_2533 Escherichia coli E24377A 2Fe-2S ferredoxin YP_001463585.1 2527429 D 331111 CDS YP_001463586.1 157158946 5590118 complement(2527737..2528387) 1 NC_009801.1 identified by match to protein family HMM PF06293; hypothetical protein 2528387 inaA 5590118 inaA Escherichia coli E24377A hypothetical protein YP_001463586.1 2527737 R 331111 CDS YP_001463587.1 157157241 5586389 2528602..2528808 1 NC_009801.1 hypothetical protein 2528808 5586389 EcE24377A_2535 Escherichia coli E24377A hypothetical protein YP_001463587.1 2528602 D 331111 CDS YP_001463588.1 157157861 5587706 complement(2528850..2529926) 1 NC_009801.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 2529926 glpQ 5587706 glpQ Escherichia coli E24377A glycerophosphodiester phosphodiesterase YP_001463588.1 2528850 R 331111 CDS YP_001463589.1 157156117 5587723 complement(2529931..2531289) 1 NC_009801.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 2531289 glpT 5587723 glpT Escherichia coli E24377A sn-glycerol-3-phosphate transporter YP_001463589.1 2529931 R 331111 CDS YP_001463590.1 157156931 5588815 2531340..2531537 1 NC_009801.1 identified by glimmer; hypothetical protein 2531537 5588815 EcE24377A_2538 Escherichia coli E24377A hypothetical protein YP_001463590.1 2531340 D 331111 CDS YP_001463591.1 157155213 5590487 2531562..2533190 1 NC_009801.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2533190 glpA 5590487 glpA Escherichia coli E24377A sn-glycerol-3-phosphate dehydrogenase subunit A YP_001463591.1 2531562 D 331111 CDS YP_001463592.1 157155773 5586856 2533180..2534439 1 NC_009801.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2534439 glpB 5586856 glpB Escherichia coli E24377A anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_001463592.1 2533180 D 331111 CDS YP_001463593.1 157156419 5586150 2534436..2535626 1 NC_009801.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2535626 glpC 5586150 glpC Escherichia coli E24377A sn-glycerol-3-phosphate dehydrogenase subunit C YP_001463593.1 2534436 D 331111 CDS YP_001463594.1 157156837 5588847 2535820..2536722 1 NC_009801.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein 2536722 5588847 EcE24377A_2542 Escherichia coli E24377A hypothetical protein YP_001463594.1 2535820 D 331111 CDS YP_001463595.1 157156572 5586079 complement(2536763..2537275) 1 NC_009801.1 identified by match to protein family HMM PF03328; HpcH/HpaI aldolase/citrate lyase 2537275 5586079 EcE24377A_2543 Escherichia coli E24377A HpcH/HpaI aldolase/citrate lyase YP_001463595.1 2536763 R 331111 CDS YP_001463596.1 157158520 5588073 complement(2537288..2538490) 1 NC_009801.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR00200; competence damage-inducible protein A 2538490 5588073 EcE24377A_2544 Escherichia coli E24377A competence damage-inducible protein A YP_001463596.1 2537288 R 331111 CDS YP_001463597.1 157156254 5590538 complement(2538590..2539132) 1 NC_009801.1 identified by similarity to SP:P76471; match to protein family HMM PF07437; outer membrane protein, YfaZ 2539132 5590538 EcE24377A_2545 Escherichia coli E24377A outer membrane protein, YfaZ YP_001463597.1 2538590 R 331111 CDS YP_001463598.1 157156936 5590356 2539411..2539836 1 NC_009801.1 identified by match to protein family HMM PF00293; NUDIX family hydrolase 2539836 5590356 EcE24377A_2546 Escherichia coli E24377A NUDIX family hydrolase YP_001463598.1 2539411 D 331111 CDS YP_001463599.1 157159312 5587819 complement(2539875..2540477) 1 NC_009801.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase 2540477 5587819 EcE24377A_2547 Escherichia coli E24377A phosphoglycerate mutase YP_001463599.1 2539875 R 331111 CDS YP_001463600.1 157155035 5588184 2540785..2541924 1 NC_009801.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2541924 arnB 5588184 arnB Escherichia coli E24377A UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase YP_001463600.1 2540785 D 331111 CDS YP_001463601.1 157158548 5589611 2541928..2542896 1 NC_009801.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2542896 arnC 5589611 arnC Escherichia coli E24377A undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_001463601.1 2541928 D 331111 CDS YP_001463602.1 157159038 5588571 2542896..2544878 1 NC_009801.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2544878 arnA 5588571 arnA Escherichia coli E24377A bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase YP_001463602.1 2542896 D 331111 CDS YP_001463603.1 157155478 5589727 2544875..2545765 1 NC_009801.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase 2545765 5589727 EcE24377A_2551 Escherichia coli E24377A polysaccharide deacetylase YP_001463603.1 2544875 D 331111 CDS YP_001463604.1 157154965 5589233 2545765..2547417 1 NC_009801.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2547417 arnT 5589233 arnT Escherichia coli E24377A 4-amino-4-deoxy-L-arabinose transferase YP_001463604.1 2545765 D 331111 CDS YP_001463605.1 157155030 5590443 2547414..2547749 1 NC_009801.1 identified by match to protein family HMM PF00893; SMR family multidrug efflux pump 2547749 5590443 EcE24377A_2553 Escherichia coli E24377A SMR family multidrug efflux pump YP_001463605.1 2547414 D 331111 CDS YP_001463606.1 157158788 5589357 2547749..2548135 1 NC_009801.1 hypothetical protein 2548135 5589357 EcE24377A_2555 Escherichia coli E24377A hypothetical protein YP_001463606.1 2547749 D 331111 CDS YP_001463607.1 157157275 5587872 complement(2548129..2548395) 1 NC_009801.1 identified by similarity to SP:P37590; polymyxin B resistance protein pmrD 2548395 pmrD 5587872 pmrD Escherichia coli E24377A polymyxin B resistance protein pmrD YP_001463607.1 2548129 R 331111 CDS YP_001463608.1 157158327 5589835 complement(2548505..2549860) 1 NC_009801.1 identified by match to protein family HMM PF00501; match to protein family HMM TIGR01923; O-succinylbenzoic acid--CoA ligase 2549860 menE 5589835 menE Escherichia coli E24377A O-succinylbenzoic acid--CoA ligase YP_001463608.1 2548505 R 331111 CDS YP_001463609.1 157158055 5588411 complement(2549857..2550819) 1 NC_009801.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 2550819 menC 5588411 menC Escherichia coli E24377A O-succinylbenzoate synthase YP_001463609.1 2549857 R 331111 CDS YP_001463610.1 157157379 5586938 complement(2550819..2551676) 1 NC_009801.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 2551676 menB 5586938 menB Escherichia coli E24377A naphthoate synthase YP_001463610.1 2550819 R 331111 CDS YP_001463611.1 157159079 5586849 complement(2551691..2552449) 1 NC_009801.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase 2552449 5586849 EcE24377A_2559 Escherichia coli E24377A acyl-CoA thioester hydrolase YP_001463611.1 2551691 R 331111 CDS YP_001463612.1 157158309 5587984 complement(2552446..2554116) 1 NC_009801.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 2554116 menD 5587984 menD Escherichia coli E24377A 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_001463612.1 2552446 R 331111 CDS YP_001463613.1 157157025 5590396 complement(2554205..2555500) 1 NC_009801.1 identified by similarity to SP:P38051; match to protein family HMM PF00425; match to protein family HMM TIGR00543; menaquinone-specific isochorismate synthase 2555500 menF 5590396 menF Escherichia coli E24377A menaquinone-specific isochorismate synthase YP_001463613.1 2554205 R 331111 CDS YP_001463614.1 157157711 5588010 complement(2555579..2555884) 1 NC_009801.1 elaB; identified by similarity to GB:CAG75914.1; match to protein family HMM PF05957; hypothetical protein 2555884 5588010 EcE24377A_2563 Escherichia coli E24377A hypothetical protein YP_001463614.1 2555579 R 331111 CDS YP_001463615.1 157158359 5587116 complement(2555939..2556400) 1 NC_009801.1 identified by match to protein family HMM PF00583; hypothetical protein 2556400 5587116 EcE24377A_2564 Escherichia coli E24377A hypothetical protein YP_001463615.1 2555939 R 331111 CDS YP_001463616.1 157158471 5586937 2556465..2557382 1 NC_009801.1 member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2557382 rnz 5586937 rnz Escherichia coli E24377A ribonuclease Z YP_001463616.1 2556465 D 331111 CDS YP_001463617.1 157159127 5588470 2557573..2558790 1 NC_009801.1 ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system; deubiquitinase 2558790 5588470 EcE24377A_2566 Escherichia coli E24377A deubiquitinase YP_001463617.1 2557573 D 331111 CDS YP_001463618.1 157155210 5586248 2559920..2560423 1 NC_009801.1 identified by similarity to GB:BAB36582.1; match to protein family HMM PF08974; hypothetical protein 2560423 5586248 EcE24377A_2568 Escherichia coli E24377A hypothetical protein YP_001463618.1 2559920 D 331111 CDS YP_001463619.1 157156426 5587353 complement(2560490..2561947) 1 NC_009801.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 2561947 nuoN 5587353 nuoN Escherichia coli E24377A NADH dehydrogenase subunit N YP_001463619.1 2560490 R 331111 CDS YP_001463620.1 157157094 5586728 complement(2561954..2563483) 1 NC_009801.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 2563483 nuoM 5586728 nuoM Escherichia coli E24377A NADH dehydrogenase subunit M YP_001463620.1 2561954 R 331111 CDS YP_001463621.1 157157147 5586844 complement(2563647..2565488) 1 NC_009801.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 2565488 nuoL 5586844 nuoL Escherichia coli E24377A NADH dehydrogenase subunit L YP_001463621.1 2563647 R 331111 CDS YP_001463622.1 157157786 5590713 complement(2565485..2565787) 1 NC_009801.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 2565787 nuoK 5590713 nuoK Escherichia coli E24377A NADH dehydrogenase subunit K YP_001463622.1 2565485 R 331111 CDS YP_001463623.1 157157709 5589421 complement(2565784..2566338) 1 NC_009801.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 2566338 nuoJ 5589421 nuoJ Escherichia coli E24377A NADH dehydrogenase subunit J YP_001463623.1 2565784 R 331111 CDS YP_001463624.1 157157555 5590693 complement(2566350..2566892) 1 NC_009801.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 2566892 nuoI 5590693 nuoI Escherichia coli E24377A NADH dehydrogenase subunit I YP_001463624.1 2566350 R 331111 CDS YP_001463625.1 157156632 5589260 complement(2566907..2567884) 1 NC_009801.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 2567884 nuoH 5589260 nuoH Escherichia coli E24377A NADH dehydrogenase subunit H YP_001463625.1 2566907 R 331111 CDS YP_001463626.1 157156000 5586355 complement(2567881..2570607) 1 NC_009801.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 2570607 nuoG 5586355 nuoG Escherichia coli E24377A NADH dehydrogenase subunit G YP_001463626.1 2567881 R 331111 CDS YP_001463627.1 157155010 5586623 complement(2570660..2571997) 1 NC_009801.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 2571997 nuoF 5586623 nuoF Escherichia coli E24377A NADH dehydrogenase I subunit F YP_001463627.1 2570660 R 331111 CDS YP_001463628.1 157154944 5590838 complement(2571994..2572494) 1 NC_009801.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 2572494 nuoE 5590838 nuoE Escherichia coli E24377A NADH dehydrogenase subunit E YP_001463628.1 2571994 R 331111 CDS YP_001463629.1 157158752 5587429 complement(2572497..2574299) 1 NC_009801.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D 2574299 nuoC 5587429 nuoC Escherichia coli E24377A bifunctional NADH:ubiquinone oxidoreductase subunit C/D YP_001463629.1 2572497 R 331111 CDS YP_001463630.1 157155733 5588624 complement(2574393..2575055) 1 NC_009801.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 2575055 nuoB 5588624 nuoB Escherichia coli E24377A NADH dehydrogenase subunit B YP_001463630.1 2574393 R 331111 CDS YP_001463631.1 157157146 5590795 complement(2575071..2575514) 1 NC_009801.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 2575514 nuoA 5590795 nuoA Escherichia coli E24377A NADH dehydrogenase subunit A YP_001463631.1 2575071 R 331111 CDS YP_001463632.1 157159005 5589406 complement(2576145..2577083) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; transcriptional regulator LrhA 2577083 lrhA 5589406 lrhA Escherichia coli E24377A transcriptional regulator LrhA YP_001463632.1 2576145 R 331111 CDS YP_001463633.1 157159307 5587740 2578003..2579220 1 NC_009801.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 2579220 5587740 EcE24377A_2583 Escherichia coli E24377A aminotransferase YP_001463633.1 2578003 D 331111 CDS YP_001463634.1 157157605 5588997 2579304..2579903 1 NC_009801.1 identified by similarity to SP:P76491; match to protein family HMM PF01966; hypothetical protein 2579903 yfbR 5588997 yfbR Escherichia coli E24377A hypothetical protein YP_001463634.1 2579304 D 331111 CDS YP_001463635.1 157158626 5586985 complement(2579962..2581794) 1 NC_009801.1 identified by match to protein family HMM PF02080; match to protein family HMM PF03600; match to protein family HMM PF06808; transporter 2581794 5586985 EcE24377A_2585 Escherichia coli E24377A transporter YP_001463635.1 2579962 R 331111 CDS YP_001463636.1 157159313 5587270 complement(2581881..2582531) 1 NC_009801.1 identified by similarity to SP:P77625; match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; phosphatase 2582531 yfbT 5587270 yfbT Escherichia coli E24377A phosphatase YP_001463636.1 2581881 R 331111 CDS YP_001463637.1 157156942 5588185 complement(2582542..2583036) 1 NC_009801.1 identified by match to protein family HMM PF03887; hypothetical protein 2583036 5588185 EcE24377A_2587 Escherichia coli E24377A hypothetical protein YP_001463637.1 2582542 R 331111 CDS YP_001463638.1 157156259 5588036 complement(2583119..2583574) 1 NC_009801.1 identified by match to protein family HMM PF04217; hypothetical protein 2583574 5588036 EcE24377A_2588 Escherichia coli E24377A hypothetical protein YP_001463638.1 2583119 R 331111 CDS YP_001463639.1 157156614 5590240 complement(2583643..2583774) 1 NC_009801.1 identified by similarity to GB:AAN81291.1; hypothetical protein 2583774 5590240 EcE24377A_2589 Escherichia coli E24377A hypothetical protein YP_001463639.1 2583643 R 331111 CDS YP_001463640.1 157154866 5590772 2583912..2585114 1 NC_009801.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2585114 ackA 5590772 ackA Escherichia coli E24377A acetate kinase YP_001463640.1 2583912 D 331111 CDS YP_001463641.1 157158227 5590733 2585189..2587333 1 NC_009801.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2587333 5590733 EcE24377A_2591 Escherichia coli E24377A phosphate acetyltransferase YP_001463641.1 2585189 D 331111 CDS YP_001463642.1 157157153 5588233 2587502..2589043 1 NC_009801.1 identified by match to protein family HMM PF03606; hypothetical protein 2589043 5588233 EcE24377A_2592 Escherichia coli E24377A hypothetical protein YP_001463642.1 2587502 D 331111 CDS YP_001463643.1 157157793 5588898 complement(2589076..2589618) 1 NC_009801.1 identified by match to protein family HMM PF00293; NUDIX family hydrolase 2589618 5588898 EcE24377A_2593 Escherichia coli E24377A NUDIX family hydrolase YP_001463643.1 2589076 R 331111 CDS YP_001463644.1 157158647 5587809 complement(2589676..2590227) 1 NC_009801.1 identified by similarity to SP:P67095; match to protein family HMM PF00149; match to protein family HMM TIGR00040; phosphodiesterase 2590227 5587809 EcE24377A_2594 Escherichia coli E24377A phosphodiesterase YP_001463644.1 2589676 R 331111 CDS YP_001463645.1 157159322 5588749 complement(2590283..2590927) 1 NC_009801.1 identified by match to protein family HMM PF02798; glutathione S-transferase domain-containing protein 2590927 5588749 EcE24377A_2595 Escherichia coli E24377A glutathione S-transferase domain-containing protein YP_001463645.1 2590283 R 331111 CDS YP_001463646.1 157157635 5589314 2591063..2591710 1 NC_009801.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase 2591710 5589314 EcE24377A_2596 Escherichia coli E24377A glutathione S-transferase YP_001463646.1 2591063 D 331111 CDS YP_001463647.1 157158308 5590760 2591767..2592129 1 NC_009801.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2592129 folX 5590760 folX Escherichia coli E24377A D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase YP_001463647.1 2591767 D 331111 CDS YP_001463648.1 157156654 5587396 2592150..2593043 1 NC_009801.1 identified by match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM PF08338; match to protein family HMM TIGR01777; NAD-binding domain-containing protein 2593043 5587396 EcE24377A_2598 Escherichia coli E24377A NAD-binding domain-containing protein YP_001463648.1 2592150 D 331111 CDS YP_001463649.1 157157264 5589568 complement(2593091..2593981) 1 NC_009801.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein 2593981 5589568 EcE24377A_2599 Escherichia coli E24377A hypothetical protein YP_001463649.1 2593091 R 331111 CDS YP_001463650.1 157155528 5588367 complement(2594178..2594951) 1 NC_009801.1 identified by match to protein family HMM PF00005; histidine/lysine/arginine/ornithine transporter subunit 2594951 hisP 5588367 hisP Escherichia coli E24377A histidine/lysine/arginine/ornithine transporter subunit YP_001463650.1 2594178 R 331111 CDS YP_001463651.1 157156249 5587588 complement(2594959..2595675) 1 NC_009801.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; histidine ABC transporter permease HisM 2595675 hisM 5587588 hisM Escherichia coli E24377A histidine ABC transporter permease HisM YP_001463651.1 2594959 R 331111 CDS YP_001463652.1 157158838 5586385 complement(2595672..2596358) 1 NC_009801.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; histidine ABC transporter permease HisQ 2596358 hisQ 5586385 hisQ Escherichia coli E24377A histidine ABC transporter permease HisQ YP_001463652.1 2595672 R 331111 CDS YP_001463653.1 157159349 5588882 complement(2596448..2597230) 1 NC_009801.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096; histidine ABC transporter periplasmic histidine-binding protein 2597230 hisJ 5588882 hisJ Escherichia coli E24377A histidine ABC transporter periplasmic histidine-binding protein YP_001463653.1 2596448 R 331111 CDS YP_001463654.1 157157871 5585981 complement(2597451..2598233) 1 NC_009801.1 identified by similarity to SP:P09551; match to protein family HMM PF00497; match to protein family HMM TIGR01096; lysine-arginine-ornithine-binding periplasmic protein 2598233 argT 5585981 argT Escherichia coli E24377A lysine-arginine-ornithine-binding periplasmic protein YP_001463654.1 2597451 R 331111 CDS YP_001463655.1 157157444 5588692 complement(2598499..2599068) 1 NC_009801.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 2599068 ubiX 5588692 ubiX Escherichia coli E24377A 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001463655.1 2598499 R 331111 CDS YP_001463656.1 157156919 5586729 complement(2599163..2600680) 1 NC_009801.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 2600680 purF 5586729 purF Escherichia coli E24377A amidophosphoribosyltransferase YP_001463656.1 2599163 R 331111 CDS YP_001463657.1 157156389 5587822 complement(2600717..2601205) 1 NC_009801.1 membrane protein required for colicin V production; colicin V production protein 2601205 cvpA 5587822 cvpA Escherichia coli E24377A colicin V production protein YP_001463657.1 2600717 R 331111 CDS YP_001463658.1 157155823 5587533 complement(2601464..2602126) 1 NC_009801.1 identified by match to protein family HMM PF05036; hypothetical protein 2602126 5587533 EcE24377A_2608 Escherichia coli E24377A hypothetical protein YP_001463658.1 2601464 R 331111 CDS YP_001463659.1 157155272 5589962 complement(2602116..2603384) 1 NC_009801.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 2603384 folC 5589962 folC Escherichia coli E24377A bifunctional folylpolyglutamate synthase/ dihydrofolate synthase YP_001463659.1 2602116 R 331111 CDS YP_001463660.1 157158344 5588950 complement(2603454..2604368) 1 NC_009801.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 2604368 accD 5588950 accD Escherichia coli E24377A acetyl-CoA carboxylase subunit beta YP_001463660.1 2603454 R 331111 CDS YP_001463661.1 157155466 5589138 complement(2604524..2605183) 1 NC_009801.1 identified by match to protein family HMM PF09335; hypothetical protein 2605183 5589138 EcE24377A_2611 Escherichia coli E24377A hypothetical protein YP_001463661.1 2604524 R 331111 CDS YP_001463662.1 157155365 5588877 complement(2605266..2606078) 1 NC_009801.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 2606078 truA 5588877 truA Escherichia coli E24377A tRNA pseudouridine synthase A YP_001463662.1 2605266 R 331111 CDS YP_001463663.1 157154856 5590066 complement(2606078..2607091) 1 NC_009801.1 identified by similarity to SP:P08390; match to protein family HMM PF01118; match to protein family HMM PF02774; semialdehyde dehydrogenase 2607091 5590066 EcE24377A_2613 Escherichia coli E24377A semialdehyde dehydrogenase YP_001463663.1 2606078 R 331111 CDS YP_001463664.1 157155347 5589738 2607072..2607185 1 NC_009801.1 identified by glimmer; hypothetical protein 2607185 5589738 EcE24377A_2615 Escherichia coli E24377A hypothetical protein YP_001463664.1 2607072 D 331111 CDS YP_001463665.1 157159447 5590697 complement(2607157..2608293) 1 NC_009801.1 identified by similarity to SP:P05459; match to protein family HMM PF00389; match to protein family HMM PF02826; erythronate-4-phosphate dehydrogenase 2608293 pdxB 5590697 pdxB Escherichia coli E24377A erythronate-4-phosphate dehydrogenase YP_001463665.1 2607157 R 331111 CDS YP_001463666.1 157158102 5588628 2608393..2609397 1 NC_009801.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2609397 flk 5588628 flk Escherichia coli E24377A flagella biosynthesis regulator YP_001463666.1 2608393 D 331111 CDS YP_001463667.1 157157524 5588945 complement(2609394..2610572) 1 NC_009801.1 identified by match to protein family HMM PF07690; hypothetical protein 2610572 5588945 EcE24377A_2616 Escherichia coli E24377A hypothetical protein YP_001463667.1 2609394 R 331111 CDS YP_001463668.1 157156872 5589877 complement(2610804..2612024) 1 NC_009801.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 2612024 fabB 5589877 fabB Escherichia coli E24377A 3-oxoacyl-ACP synthase YP_001463668.1 2610804 R 331111 CDS YP_001463669.1 157157358 5587831 2612183..2614189 1 NC_009801.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2614189 mnmC 5587831 mnmC Escherichia coli E24377A 5-methylaminomethyl-2-thiouridine methyltransferase YP_001463669.1 2612183 D 331111 CDS YP_001463670.1 157155830 5587905 complement(2614245..2614523) 1 NC_009801.1 identified by similarity to GB:ABB66925.1; match to protein family HMM PF08891; hypothetical protein 2614523 5587905 EcE24377A_2620 Escherichia coli E24377A hypothetical protein YP_001463670.1 2614245 R 331111 CDS YP_001463671.1 157156358 5587343 complement(2614557..2615105) 1 NC_009801.1 identified by match to protein family HMM PF04315; hypothetical protein 2615105 5587343 EcE24377A_2621 Escherichia coli E24377A hypothetical protein YP_001463671.1 2614557 R 331111 CDS YP_001463672.1 157155594 5590646 complement(2615105..2615914) 1 NC_009801.1 identified by match to protein family HMM PF01925; hypothetical protein 2615914 5590646 EcE24377A_2622 Escherichia coli E24377A hypothetical protein YP_001463672.1 2615105 R 331111 CDS YP_001463673.1 157156902 5587163 complement(2615914..2616738) 1 NC_009801.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 2616738 mepA 5587163 mepA Escherichia coli E24377A penicillin-insensitive murein endopeptidase YP_001463673.1 2615914 R 331111 CDS YP_001463674.1 157155097 5586436 complement(2616742..2617827) 1 NC_009801.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 2617827 aroC 5586436 aroC Escherichia coli E24377A chorismate synthase YP_001463674.1 2616742 R 331111 CDS YP_001463675.1 157155888 5588605 complement(2617986..2618918) 1 NC_009801.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 2618918 prmB 5588605 prmB Escherichia coli E24377A N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_001463675.1 2617986 R 331111 CDS YP_001463676.1 157158361 5588603 2619084..2619635 1 NC_009801.1 identified by match to protein family HMM PF01713; hypothetical protein 2619635 5588603 EcE24377A_2626 Escherichia coli E24377A hypothetical protein YP_001463676.1 2619084 D 331111 CDS YP_001463677.1 157158957 5590814 complement(2619708..2620577) 1 NC_009801.1 identified by similarity to GB:ABB66932.1; hypothetical protein 2620577 5590814 EcE24377A_2627 Escherichia coli E24377A hypothetical protein YP_001463677.1 2619708 R 331111 CDS YP_001463678.1 157157406 5586308 complement(2620564..2621103) 1 NC_009801.1 identified by match to protein family HMM PF00419; fimbrial protein 2621103 5586308 EcE24377A_2628 Escherichia coli E24377A fimbrial protein YP_001463678.1 2620564 R 331111 CDS YP_001463679.1 157157908 5589006 complement(2621100..2621588) 1 NC_009801.1 hypothetical protein 2621588 5589006 EcE24377A_2629 Escherichia coli E24377A hypothetical protein YP_001463679.1 2621100 R 331111 CDS YP_001463680.1 157156990 5588441 complement(2621585..2622088) 1 NC_009801.1 identified by similarity to GB:AAV76235.1; fimbrial protein 2622088 5588441 EcE24377A_2630 Escherichia coli E24377A fimbrial protein YP_001463680.1 2621585 R 331111 CDS YP_001463681.1 157157497 5590575 complement(2622104..2622829) 1 NC_009801.1 identified by match to protein family HMM PF00345; periplasmic pilus chaperone family protein 2622829 5590575 EcE24377A_2631 Escherichia coli E24377A periplasmic pilus chaperone family protein YP_001463681.1 2622104 R 331111 CDS YP_001463682.1 157157222 5588804 2622702..2622890 1 NC_009801.1 identified by glimmer; hypothetical protein 2622890 5588804 EcE24377A_2633 Escherichia coli E24377A hypothetical protein YP_001463682.1 2622702 D 331111 CDS YP_001463683.1 157157705 5590056 complement(2622876..2625521) 1 NC_009801.1 identified by match to protein family HMM PF00577; fimbrial usher family protein 2625521 5590056 EcE24377A_2632 Escherichia coli E24377A fimbrial usher family protein YP_001463683.1 2622876 R 331111 CDS YP_001463684.1 157156883 5586447 2625510..2626046 1 NC_009801.1 identified by glimmer; hypothetical protein 2626046 5586447 EcE24377A_2635 Escherichia coli E24377A hypothetical protein YP_001463684.1 2625510 D 331111 CDS YP_001463685.1 157156367 5586835 complement(2625603..2626166) 1 NC_009801.1 identified by similarity to GB:AAC64152.1; match to protein family HMM PF00419; fimbrial protein 2626166 5586835 EcE24377A_2634 Escherichia coli E24377A fimbrial protein YP_001463685.1 2625603 R 331111 CDS YP_001463686.1 157155292 5590075 complement(2626850..2627335) 1 NC_009801.1 identified by match to protein family HMM PF00300; match to protein family HMM TIGR00249; phosphohistidine phosphatase 2627335 sixA 5590075 sixA Escherichia coli E24377A phosphohistidine phosphatase YP_001463686.1 2626850 R 331111 CDS YP_001463687.1 157155802 5588861 complement(2627538..2629682) 1 NC_009801.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 2629682 fadJ 5588861 fadJ Escherichia coli E24377A multifunctional fatty acid oxidation complex subunit alpha YP_001463687.1 2627538 R 331111 CDS YP_001463688.1 157158369 5590384 complement(2629682..2630992) 1 NC_009801.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 2630992 fadI 5590384 fadI Escherichia coli E24377A 3-ketoacyl-CoA thiolase YP_001463688.1 2629682 R 331111 CDS YP_001463689.1 157158947 5588063 complement(2631172..2631456) 1 NC_009801.1 identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743; hypothetical protein 2631456 5588063 EcE24377A_2639 Escherichia coli E24377A hypothetical protein YP_001463689.1 2631172 R 331111 CDS YP_001463690.1 157157341 5586390 2631828..2633168 1 NC_009801.1 identified by match to protein family HMM PF03349; long-chain fatty acid outer membrane transporter 2633168 5586390 EcE24377A_2640 Escherichia coli E24377A long-chain fatty acid outer membrane transporter YP_001463690.1 2631828 D 331111 CDS YP_001463691.1 157157915 5586567 2633535..2634593 1 NC_009801.1 identified by similarity to GB:AAP17747.1; hypothetical protein 2634593 5586567 EcE24377A_2641 Escherichia coli E24377A hypothetical protein YP_001463691.1 2633535 D 331111 CDS YP_001463692.1 157156646 5590471 complement(2634775..2635530) 1 NC_009801.1 identified by match to protein family HMM PF04333; VacJ family lipoprotein 2635530 5590471 EcE24377A_2642 Escherichia coli E24377A VacJ family lipoprotein YP_001463692.1 2634775 R 331111 CDS YP_001463693.1 157154743 5589134 complement(2635556..2635726) 1 NC_009801.1 identified by similarity to GB:AAN81341.1; hypothetical protein 2635726 5589134 EcE24377A_2643 Escherichia coli E24377A hypothetical protein YP_001463693.1 2635556 R 331111 CDS YP_001463694.1 157156775 5586683 2635824..2636756 1 NC_009801.1 hypothetical protein 2636756 5586683 EcE24377A_2644 Escherichia coli E24377A hypothetical protein YP_001463694.1 2635824 D 331111 CDS YP_001463695.1 157154895 5589143 complement(2637347..2638594) 1 NC_009801.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 2638594 lacY 5589143 lacY Escherichia coli E24377A galactoside permease YP_001463695.1 2637347 R 331111 CDS YP_001463696.1 157158692 5588045 complement(2638666..2639580) 1 NC_009801.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase 2639580 cscK 5588045 cscK Escherichia coli E24377A aminoimidazole riboside kinase YP_001463696.1 2638666 R 331111 CDS YP_001463697.1 157159186 5588290 2639702..2639794 1 NC_009801.1 identified by glimmer; hypothetical protein 2639794 5588290 EcE24377A_2648 Escherichia coli E24377A hypothetical protein YP_001463697.1 2639702 D 331111 CDS YP_001463698.1 157158158 5586160 2639787..2641229 1 NC_009801.1 identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322; sucrose-6-phosphate hydrolase 2641229 5586160 EcE24377A_2649 Escherichia coli E24377A sucrose-6-phosphate hydrolase YP_001463698.1 2639787 D 331111 CDS YP_001463699.1 157156023 5586147 complement(2641237..2642232) 1 NC_009801.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; LacI family sucrose operon repressor 2642232 5586147 EcE24377A_2650 Escherichia coli E24377A LacI family sucrose operon repressor YP_001463699.1 2641237 R 331111 CDS YP_001463700.1 157156581 5586441 2642475..2642693 1 NC_009801.1 identified by glimmer; hypothetical protein 2642693 5586441 EcE24377A_2651 Escherichia coli E24377A hypothetical protein YP_001463700.1 2642475 D 331111 CDS YP_001463701.1 157158819 5586459 2642711..2644039 1 NC_009801.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 2644039 dsdA 5586459 dsdA Escherichia coli E24377A D-serine dehydratase YP_001463701.1 2642711 D 331111 CDS YP_001463702.1 157157326 5590262 complement(2644147..2645685) 1 NC_009801.1 identified by similarity to SP:P52600; match to protein family HMM PF07690; match to protein family HMM TIGR00711; DHA2 family drug:H+ antiporter-1 2645685 emrY 5590262 emrY Escherichia coli E24377A DHA2 family drug:H+ antiporter-1 YP_001463702.1 2644147 R 331111 CDS YP_001463703.1 157155084 5589823 complement(2645685..2646848) 1 NC_009801.1 identified by similarity to SP:P52599; match to protein family HMM PF00529; match to protein family HMM TIGR00998; drug resistance MFS transporter membrane fusion protein (MFP) subunit EmrK 2646848 emrK 5589823 emrK Escherichia coli E24377A drug resistance MFS transporter membrane fusion protein (MFP) subunit EmrK YP_001463703.1 2645685 R 331111 CDS YP_001463704.1 157155607 5588369 2647264..2647878 1 NC_009801.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 2647878 evgA 5588369 evgA Escherichia coli E24377A DNA-binding transcriptional activator EvgA YP_001463704.1 2647264 D 331111 CDS YP_001463705.1 157157004 5587935 2647883..2651476 1 NC_009801.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00497; match to protein family HMM PF00512; match to protein family HMM PF01627; match to protein family HMM PF02518; hybrid sensory histidine kinase in two-component regulatory system with EvgA 2651476 evgS 5587935 evgS Escherichia coli E24377A hybrid sensory histidine kinase in two-component regulatory system with EvgA YP_001463705.1 2647883 D 331111 CDS YP_001463706.1 157156467 5590293 complement(2651252..2651350) 1 NC_009801.1 identified by glimmer; hypothetical protein 2651350 5590293 EcE24377A_2656 Escherichia coli E24377A hypothetical protein YP_001463706.1 2651252 R 331111 CDS YP_001463707.1 157155978 5586072 complement(2651532..2652677) 1 NC_009801.1 identified by match to protein family HMM PF02515; hypothetical protein 2652677 5586072 EcE24377A_2658 Escherichia coli E24377A hypothetical protein YP_001463707.1 2651532 R 331111 CDS YP_001463708.1 157157512 5589613 2652671..2652775 1 NC_009801.1 identified by glimmer; hypothetical protein 2652775 5589613 EcE24377A_2660 Escherichia coli E24377A hypothetical protein YP_001463708.1 2652671 D 331111 CDS YP_001463709.1 157156710 5589686 complement(2652751..2653695) 1 NC_009801.1 member of the AEC family of auxin efflux transporters; unknown function; transporter YfdV 2653695 5589686 EcE24377A_2659 Escherichia coli E24377A transporter YfdV YP_001463709.1 2652751 R 331111 CDS YP_001463710.1 157158048 5588127 complement(2653765..2655459) 1 NC_009801.1 catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase 2655459 5588127 EcE24377A_2661 Escherichia coli E24377A oxalyl-CoA decarboxylase YP_001463710.1 2653765 R 331111 CDS YP_001463711.1 157156745 5586087 complement(2655513..2656763) 1 NC_009801.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 2656763 frc 5586087 frc Escherichia coli E24377A formyl-coenzyme A transferase YP_001463711.1 2655513 R 331111 CDS YP_001463712.1 157157931 5589157 complement(2657276..2657908) 1 NC_009801.1 identified by similarity to GB:AAZ89107.1; hypothetical protein 2657908 5589157 EcE24377A_2663 Escherichia coli E24377A hypothetical protein YP_001463712.1 2657276 R 331111 CDS YP_001463713.1 157157284 5589104 complement(2658464..2658601) 1 NC_009801.1 identified by glimmer; hypothetical protein 2658601 5589104 EcE24377A_2664 Escherichia coli E24377A hypothetical protein YP_001463713.1 2658464 R 331111 CDS YP_001463714.1 157156965 5587502 complement(2658556..2658798) 1 NC_009801.1 identified by similarity to GB:AAZ89109.1; hypothetical protein 2658798 5587502 EcE24377A_2665 Escherichia coli E24377A hypothetical protein YP_001463714.1 2658556 R 331111 CDS YP_001463715.1 157156269 5586700 2659151..2660071 1 NC_009801.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2660071 5586700 EcE24377A_2666 Escherichia coli E24377A lipid A biosynthesis palmitoleoyl acyltransferase YP_001463715.1 2659151 D 331111 CDS YP_001463716.1 157155903 5590553 2660381..2660497 1 NC_009801.1 identified by glimmer; hypothetical protein 2660497 5590553 EcE24377A_2667 Escherichia coli E24377A hypothetical protein YP_001463716.1 2660381 D 331111 CDS YP_001463717.1 157155217 5586641 complement(2660562..2661800) 1 NC_009801.1 identified by match to protein family HMM PF00155; aminotransferase 2661800 5586641 EcE24377A_2668 Escherichia coli E24377A aminotransferase YP_001463717.1 2660562 R 331111 CDS YP_001463718.1 157158466 5586754 complement(2661719..2661853) 1 NC_009801.1 identified by glimmer; hypothetical protein 2661853 5586754 EcE24377A_2669 Escherichia coli E24377A hypothetical protein YP_001463718.1 2661719 R 331111 CDS YP_001463719.1 157155409 5586671 2662195..2663874 1 NC_009801.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694; sensor histidine kinase 2663874 5586671 EcE24377A_2670 Escherichia coli E24377A sensor histidine kinase YP_001463719.1 2662195 D 331111 CDS YP_001463720.1 157157403 5589798 2663889..2664623 1 NC_009801.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397; response regulator 2664623 5589798 EcE24377A_2671 Escherichia coli E24377A response regulator YP_001463720.1 2663889 D 331111 CDS YP_001463721.1 157155013 5588930 2664636..2665493 1 NC_009801.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 2665493 5588930 EcE24377A_2672 Escherichia coli E24377A AraC family transcriptional regulator YP_001463721.1 2664636 D 331111 CDS YP_001463722.1 157159178 5589181 complement(2665496..2667991) 1 NC_009801.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR00848; match to protein family HMM TIGR01417; multiphosphoryl transfer protein 1 2667991 fryA 5589181 fryA Escherichia coli E24377A multiphosphoryl transfer protein 1 YP_001463722.1 2665496 R 331111 CDS YP_001463723.1 157157890 5590350 complement(2668016..2669053) 1 NC_009801.1 metalloprotein; exoaminopeptidase 2669053 5590350 EcE24377A_2674 Escherichia coli E24377A exoaminopeptidase YP_001463723.1 2668016 R 331111 CDS YP_001463724.1 157157245 5587145 complement(2669053..2670138) 1 NC_009801.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase 2670138 ypdF 5587145 ypdF Escherichia coli E24377A aminopeptidase YP_001463724.1 2669053 R 331111 CDS YP_001463725.1 157156602 5588594 complement(2670153..2671400) 1 NC_009801.1 identified by similarity to SP:Q8XBP8; match to protein family HMM PF02378; match to protein family HMM TIGR01427; PTS system fructose-like transporter subunit IIC 2671400 fryC 5588594 fryC Escherichia coli E24377A PTS system fructose-like transporter subunit IIC YP_001463725.1 2670153 R 331111 CDS YP_001463726.1 157158700 5589003 complement(2671422..2671748) 1 NC_009801.1 identified by match to protein family HMM PF02379; match to protein family HMM TIGR00829; PTS system fructose specific transporter subunit IIB subunit 2671748 5589003 EcE24377A_2677 Escherichia coli E24377A PTS system fructose specific transporter subunit IIB subunit YP_001463726.1 2671422 R 331111 CDS YP_001463727.1 157159392 5589600 complement(2671967..2672932) 1 NC_009801.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 2672932 glk 5589600 glk Escherichia coli E24377A glucokinase YP_001463727.1 2671967 R 331111 CDS YP_001463728.1 157157634 5590007 2673136..2674392 1 NC_009801.1 hypothetical protein 2674392 5590007 EcE24377A_2679 Escherichia coli E24377A hypothetical protein YP_001463728.1 2673136 D 331111 CDS YP_001463729.1 157157172 5588635 complement(2674409..2674507) 1 NC_009801.1 identified by glimmer; hypothetical protein 2674507 5588635 EcE24377A_2680 Escherichia coli E24377A hypothetical protein YP_001463729.1 2674409 R 331111 CDS YP_001463730.1 157155969 5588166 2674507..2674833 1 NC_009801.1 identified by similarity to SP:P64544; hypothetical protein 2674833 5588166 EcE24377A_2681 Escherichia coli E24377A hypothetical protein YP_001463730.1 2674507 D 331111 CDS YP_001463731.1 157155133 5590069 complement(2674974..2676212) 1 NC_009801.1 identified by match to protein family HMM PF01566; match to protein family HMM TIGR01197; manganese transport protein MntH 2676212 mntH 5590069 mntH Escherichia coli E24377A manganese transport protein MntH YP_001463731.1 2674974 R 331111 CDS YP_001463732.1 157155548 5590548 2676548..2677750 1 NC_009801.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804; nucleoside transporter NupC 2677750 nupC 5590548 nupC Escherichia coli E24377A nucleoside transporter NupC YP_001463732.1 2676548 D 331111 CDS YP_001463733.1 157159235 5590270 complement(2677800..2679989) 1 NC_009801.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF05231; diguanylate cyclase 2679989 5590270 EcE24377A_2684 Escherichia coli E24377A diguanylate cyclase YP_001463733.1 2677800 R 331111 CDS YP_001463734.1 157157542 5586561 2680623..2680967 1 NC_009801.1 hypothetical protein 2680967 5586561 EcE24377A_2687 Escherichia coli E24377A hypothetical protein YP_001463734.1 2680623 D 331111 CDS YP_001463735.1 157154838 5588420 2680969..2681361 1 NC_009801.1 identified by match to protein family HMM PF07037; hypothetical protein 2681361 5588420 EcE24377A_2688 Escherichia coli E24377A hypothetical protein YP_001463735.1 2680969 D 331111 CDS YP_001463736.1 157156721 5585918 complement(2681413..2682828) 1 NC_009801.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2682828 gltX 5585918 gltX Escherichia coli E24377A glutamyl-tRNA synthetase YP_001463736.1 2681413 R 331111 CDS YP_001463737.1 157158730 5587465 2683605..2683946 1 NC_009801.1 identified by similarity to GB:AAP17783.1; hypothetical protein 2683946 5587465 EcE24377A_2695 Escherichia coli E24377A hypothetical protein YP_001463737.1 2683605 D 331111 CDS YP_001463738.1 157159187 5587640 complement(2683937..2684863) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2684863 5587640 EcE24377A_2694 Escherichia coli E24377A LysR family transcriptional regulator YP_001463738.1 2683937 R 331111 CDS YP_001463739.1 157157547 5586161 2684953..2685951 1 NC_009801.1 identified by match to protein family HMM PF01758; bile acid/Na+ symporter family protein 2685951 5586161 EcE24377A_2697 Escherichia coli E24377A bile acid/Na+ symporter family protein YP_001463739.1 2684953 D 331111 CDS YP_001463740.1 157155808 5587925 complement(2685948..2686166) 1 NC_009801.1 identified by similarity to SP:P0AD40; hypothetical protein 2686166 5587925 EcE24377A_2696 Escherichia coli E24377A hypothetical protein YP_001463740.1 2685948 R 331111 CDS YP_001463741.1 157156100 5588540 complement(2686168..2688183) 1 NC_009801.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 2688183 ligA 5588540 ligA Escherichia coli E24377A NAD-dependent DNA ligase LigA YP_001463741.1 2686168 R 331111 CDS YP_001463742.1 157156810 5588706 complement(2688254..2689240) 1 NC_009801.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 2689240 zipA 5588706 zipA Escherichia coli E24377A cell division protein ZipA YP_001463742.1 2688254 R 331111 CDS YP_001463743.1 157154763 5586863 2689470..2690231 1 NC_009801.1 role in sulfur assimilation; sulfate transport protein CysZ 2690231 cysZ 5586863 cysZ Escherichia coli E24377A sulfate transport protein CysZ YP_001463743.1 2689470 D 331111 CDS YP_001463744.1 157155432 5588839 2690416..2691387 1 NC_009801.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2691387 cysK 5588839 cysK Escherichia coli E24377A cysteine synthase A YP_001463744.1 2690416 D 331111 CDS YP_001463745.1 157158766 5587823 2691771..2692028 1 NC_009801.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003; PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr 2692028 ptsH 5587823 ptsH Escherichia coli E24377A PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr YP_001463745.1 2691771 D 331111 CDS YP_001463746.1 157159395 5589769 2692073..2693800 1 NC_009801.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 2693800 ptsI 5589769 ptsI Escherichia coli E24377A phosphoenolpyruvate-protein phosphotransferase YP_001463746.1 2692073 D 331111 CDS YP_001463747.1 157157951 5590456 2693841..2694350 1 NC_009801.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 2694350 crr 5590456 crr Escherichia coli E24377A PTS system glucose-specific transporter YP_001463747.1 2693841 D 331111 CDS YP_001463748.1 157158000 5588451 complement(2694392..2695243) 1 NC_009801.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase 2695243 pdxK 5588451 pdxK Escherichia coli E24377A pyridoxal kinase YP_001463748.1 2694392 R 331111 CDS YP_001463749.1 157157050 5586544 2695348..2695716 1 NC_009801.1 identified by similarity to GB:ABB66999.1; hypothetical protein 2695716 5586544 EcE24377A_2706 Escherichia coli E24377A hypothetical protein YP_001463749.1 2695348 D 331111 CDS YP_001463750.1 157156485 5587303 complement(2695719..2696630) 1 NC_009801.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 2696630 cysM 5587303 cysM Escherichia coli E24377A cysteine synthase B YP_001463750.1 2695719 R 331111 CDS YP_001463751.1 157156447 5590564 complement(2696764..2697861) 1 NC_009801.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR00968; sulfate/thiosulfate transporter subunit 2697861 cysA 5590564 cysA Escherichia coli E24377A sulfate/thiosulfate transporter subunit YP_001463751.1 2696764 R 331111 CDS YP_001463752.1 157155901 5587686 complement(2697851..2698726) 1 NC_009801.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit 2698726 cysW 5587686 cysW Escherichia coli E24377A sulfate/thiosulfate transporter permease subunit YP_001463752.1 2697851 R 331111 CDS YP_001463753.1 157157732 5586639 complement(2698726..2699559) 1 NC_009801.1 identified by similarity to SP:P16701; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139; sulfate/thiosulfate transporter subunit 2699559 cysT 5586639 cysT Escherichia coli E24377A sulfate/thiosulfate transporter subunit YP_001463753.1 2698726 R 331111 CDS YP_001463754.1 157157262 5589644 complement(2699559..2700575) 1 NC_009801.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971; thiosulfate transporter subunit 2700575 cysP 5589644 cysP Escherichia coli E24377A thiosulfate transporter subunit YP_001463754.1 2699559 R 331111 CDS YP_001463755.1 157158523 5589587 complement(2700733..2701524) 1 NC_009801.1 identified by similarity to SP:P37440; match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659; short chain dehydrogenase 2701524 ucpA 5589587 ucpA Escherichia coli E24377A short chain dehydrogenase YP_001463755.1 2700733 R 331111 CDS YP_001463756.1 157157722 5588154 complement(2701653..2702510) 1 NC_009801.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR family transcriptional regulator 2702510 5588154 EcE24377A_2713 Escherichia coli E24377A RpiR family transcriptional regulator YP_001463756.1 2701653 R 331111 CDS YP_001463757.1 157155139 5589393 2702674..2703570 1 NC_009801.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 2703570 murQ 5589393 murQ Escherichia coli E24377A N-acetylmuramic acid 6-phosphate etherase YP_001463757.1 2702674 D 331111 CDS YP_001463758.1 157159046 5589551 2703574..2704998 1 NC_009801.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunit IIBC 2704998 murP 5589551 murP Escherichia coli E24377A PTS system N-acetylmuramic acid transporter subunit IIBC YP_001463758.1 2703574 D 331111 CDS YP_001463759.1 157155824 5588899 2705003..2706307 1 NC_009801.1 identified by match to protein family HMM PF00144; hypothetical protein 2706307 5588899 EcE24377A_2716 Escherichia coli E24377A hypothetical protein YP_001463759.1 2705003 D 331111 CDS YP_001463760.1 157157932 5590103 complement(2706365..2707264) 1 NC_009801.1 identified by match to protein family HMM PF04261; match to protein family HMM TIGR01413; dyp-type peroxidase 2707264 5590103 EcE24377A_2717 Escherichia coli E24377A dyp-type peroxidase YP_001463760.1 2706365 R 331111 CDS YP_001463761.1 157156298 5589105 complement(2707360..2707935) 1 NC_009801.1 identified by match to protein family HMM PF06572; hypothetical protein 2707935 5589105 EcE24377A_2718 Escherichia coli E24377A hypothetical protein YP_001463761.1 2707360 R 331111 CDS YP_001463762.1 157155845 5590373 complement(2707996..2708445) 1 NC_009801.1 inner membrane protein YfeZ 2708445 5590373 EcE24377A_2719 Escherichia coli E24377A inner membrane protein YfeZ YP_001463762.1 2707996 R 331111 CDS YP_001463763.1 157155283 5587024 complement(2708432..2708857) 1 NC_009801.1 identified by match to protein family HMM PF00583; acetyltransferase 2708857 5587024 EcE24377A_2720 Escherichia coli E24377A acetyltransferase YP_001463763.1 2708432 R 331111 CDS YP_001463764.1 157156944 5588844 2709071..2709940 1 NC_009801.1 identified by similarity to SP:P36548; match to protein family HMM PF01520; match to protein family HMM TIGR01409; N-acetylmuramoyl-L-alanine amidase 2709940 amiA 5588844 amiA Escherichia coli E24377A N-acetylmuramoyl-L-alanine amidase YP_001463764.1 2709071 D 331111 CDS YP_001463765.1 157156271 5587529 2709944..2710843 1 NC_009801.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2710843 hemF 5587529 hemF Escherichia coli E24377A coproporphyrinogen III oxidase YP_001463765.1 2709944 D 331111 CDS YP_001463766.1 157155855 5588788 complement(2710849..2711901) 1 NC_009801.1 activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR 2711901 5588788 EcE24377A_2723 Escherichia coli E24377A transcriptional regulator EutR YP_001463766.1 2710849 R 331111 CDS YP_001463767.1 157155205 5587223 complement(2711947..2712447) 1 NC_009801.1 identified by similarity to SP:Q9ZFU8; match to protein family HMM PF00936; ethanolamine utilization protein EutK 2712447 5587223 EcE24377A_2724 Escherichia coli E24377A ethanolamine utilization protein EutK YP_001463767.1 2711947 R 331111 CDS YP_001463768.1 157158984 5587559 complement(2712460..2713119) 1 NC_009801.1 identified by similarity to SP:P0A1C9; match to protein family HMM PF00936; ethanolamine utilization protein EutL 2713119 5587559 EcE24377A_2725 Escherichia coli E24377A ethanolamine utilization protein EutL YP_001463768.1 2712460 R 331111 CDS YP_001463769.1 157158237 5590410 complement(2713129..2714016) 1 NC_009801.1 catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit 2714016 eutC 5590410 eutC Escherichia coli E24377A ethanolamine ammonia-lyase small subunit YP_001463769.1 2713129 R 331111 CDS YP_001463770.1 157155166 5586520 complement(2714037..2715398) 1 NC_009801.1 identified by similarity to SP:P19264; match to protein family HMM PF06751; ethanolamine ammonia-lyase, large subunit 2715398 eutB 5586520 eutB Escherichia coli E24377A ethanolamine ammonia-lyase, large subunit YP_001463770.1 2714037 R 331111 CDS YP_001463771.1 157159089 5588072 complement(2715410..2716813) 1 NC_009801.1 ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase 2716813 eutA 5588072 eutA Escherichia coli E24377A reactivating factor for ethanolamine ammonia lyase YP_001463771.1 2715410 R 331111 CDS YP_001463772.1 157155308 5590179 complement(2716810..2718036) 1 NC_009801.1 identified by similarity to SP:P41796; match to protein family HMM PF04346; ethanolamine utilization protein EutH 2718036 eutH 5590179 eutH Escherichia coli E24377A ethanolamine utilization protein EutH YP_001463772.1 2716810 R 331111 CDS YP_001463773.1 157154795 5585958 complement(2718153..2719340) 1 NC_009801.1 identified by similarity to SP:P41795; match to protein family HMM PF00465; ethanolamine utilization protein EutG 2719340 eutG 5585958 eutG Escherichia coli E24377A ethanolamine utilization protein EutG YP_001463773.1 2718153 R 331111 CDS YP_001463774.1 157155503 5588241 complement(2719330..2720166) 1 NC_009801.1 identified by similarity to SP:P0A206; match to protein family HMM TIGR02529; ethanolamine utilization protein EutJ 2720166 eutJ 5588241 eutJ Escherichia coli E24377A ethanolamine utilization protein EutJ YP_001463774.1 2719330 R 331111 CDS YP_001463775.1 157154906 5590791 complement(2720177..2721580) 1 NC_009801.1 identified by similarity to SP:P41793; match to protein family HMM PF00171; ethanolamine utilization protein EutE 2721580 eutE 5590791 eutE Escherichia coli E24377A ethanolamine utilization protein EutE YP_001463775.1 2720177 R 331111 CDS YP_001463776.1 157159231 5590400 complement(2721592..2721879) 1 NC_009801.1 identified by similarity to SP:P41792; match to protein family HMM PF03319; ethanolamine utilization protein 2721879 eutN 5590400 eutN Escherichia coli E24377A ethanolamine utilization protein YP_001463776.1 2721592 R 331111 CDS YP_001463777.1 157158705 5586316 complement(2721986..2722279) 1 NC_009801.1 identified by match to protein family HMM PF00936; ethanolamine utilization protein EutM 2722279 eutM 5586316 eutM Escherichia coli E24377A ethanolamine utilization protein EutM YP_001463777.1 2721986 R 331111 CDS YP_001463778.1 157158168 5590810 complement(2722318..2723334) 1 NC_009801.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 2723334 eutD 5590810 eutD Escherichia coli E24377A phosphotransacetylase YP_001463778.1 2722318 R 331111 CDS YP_001463779.1 157159056 5588949 complement(2723331..2724134) 1 NC_009801.1 identified by similarity to SP:Q9ZFV4; match to protein family HMM PF01923; ethanolamine utilization cobalamin adenosyltransferase 2724134 eutT 5588949 eutT Escherichia coli E24377A ethanolamine utilization cobalamin adenosyltransferase YP_001463779.1 2723331 R 331111 CDS YP_001463780.1 157159208 5586492 complement(2724131..2724832) 1 NC_009801.1 identified by match to protein family HMM PF05899; match to protein family HMM PF06249; ethanolamine utilization protein EutQ 2724832 5586492 EcE24377A_2737 Escherichia coli E24377A ethanolamine utilization protein EutQ YP_001463780.1 2724131 R 331111 CDS YP_001463781.1 157157909 5586625 complement(2724807..2725286) 1 NC_009801.1 identified by similarity to SP:P0A208; match to protein family HMM TIGR02528; ethanolamine utilization protein, EutP 2725286 eutP 5586625 eutP Escherichia coli E24377A ethanolamine utilization protein, EutP YP_001463781.1 2724807 R 331111 CDS YP_001463782.1 157157188 5588442 complement(2725299..2725706) 1 NC_009801.1 identified by similarity to SP:Q9ZFV7; match to protein family HMM PF00936; ethanolamine utilization protein EutS 2725706 5588442 EcE24377A_2739 Escherichia coli E24377A ethanolamine utilization protein EutS YP_001463782.1 2725299 R 331111 CDS YP_001463783.1 157156544 5587407 2725563..2725670 1 NC_009801.1 identified by glimmer; hypothetical protein 2725670 5587407 EcE24377A_2740 Escherichia coli E24377A hypothetical protein YP_001463783.1 2725563 D 331111 CDS YP_001463784.1 157156474 5586471 complement(2725927..2728206) 1 NC_009801.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 2728206 maeB 5586471 maeB Escherichia coli E24377A malic enzyme YP_001463784.1 2725927 R 331111 CDS YP_001463785.1 157155721 5589024 2728495..2729445 1 NC_009801.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874; transaldolase A 2729445 tal1 5589024 tal1 Escherichia coli E24377A transaldolase A YP_001463785.1 2728495 D 331111 CDS YP_001463786.1 157155048 5586382 2729465..2731468 1 NC_009801.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2731468 tktB 5586382 tktB Escherichia coli E24377A transketolase YP_001463786.1 2729465 D 331111 CDS YP_001463787.1 157155025 5585905 2731461..2731574 1 NC_009801.1 identified by glimmer; hypothetical protein 2731574 5585905 EcE24377A_2745 Escherichia coli E24377A hypothetical protein YP_001463787.1 2731461 D 331111 CDS YP_001463788.1 157155725 5589933 complement(2731564..2732607) 1 NC_009801.1 identified by similarity to GB:ABB67033.1; match to protein family HMM PF06674; hypothetical protein 2732607 5589933 EcE24377A_2744 Escherichia coli E24377A hypothetical protein YP_001463788.1 2731564 R 331111 CDS YP_001463789.1 157155986 5587625 complement(2732733..2733308) 1 NC_009801.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052; NUDIX family hydrolase 2733308 5587625 EcE24377A_2746 Escherichia coli E24377A NUDIX family hydrolase YP_001463789.1 2732733 R 331111 CDS YP_001463790.1 157155091 5588586 complement(2733376..2735355) 1 NC_009801.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 2735355 aegA 5588586 aegA Escherichia coli E24377A oxidoreductase Fe-S binding subunit YP_001463790.1 2733376 R 331111 CDS YP_001463791.1 157155766 5588686 2735561..2737261 1 NC_009801.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730; nitrate/nitrite sensor protein NarQ 2737261 narQ 5588686 narQ Escherichia coli E24377A nitrate/nitrite sensor protein NarQ YP_001463791.1 2735561 D 331111 CDS YP_001463792.1 157158507 5587667 2737425..2740538 1 NC_009801.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; aminoglycoside/multidrug efflux system 2740538 acrD 5587667 acrD Escherichia coli E24377A aminoglycoside/multidrug efflux system YP_001463792.1 2737425 D 331111 CDS YP_001463793.1 157159180 5590106 2741077..2741433 1 NC_009801.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; hypothetical protein 2741433 5590106 EcE24377A_2750 Escherichia coli E24377A hypothetical protein YP_001463793.1 2741077 D 331111 CDS YP_001463794.1 157158473 5586953 2741437..2742564 1 NC_009801.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2742564 dapE 5586953 dapE Escherichia coli E24377A succinyl-diaminopimelate desuccinylase YP_001463794.1 2741437 D 331111 CDS YP_001463795.1 157159147 5590702 2742592..2742792 1 NC_009801.1 identified by similarity to GB:AAN81450.1; hypothetical protein 2742792 5590702 EcE24377A_2752 Escherichia coli E24377A hypothetical protein YP_001463795.1 2742592 D 331111 CDS YP_001463796.1 157157118 5589720 complement(2742873..2743571) 1 NC_009801.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase 2743571 5589720 EcE24377A_2753 Escherichia coli E24377A esterase YP_001463796.1 2742873 R 331111 CDS YP_001463797.1 157157754 5590673 complement(2743645..2745660) 1 NC_009801.1 identified by similarity to GB:ABB62712.1; match to protein family HMM PF05127; hypothetical protein 2745660 5590673 EcE24377A_2754 Escherichia coli E24377A hypothetical protein YP_001463797.1 2743645 R 331111 CDS YP_001463798.1 157155162 5588236 complement(2745675..2746538) 1 NC_009801.1 identified by match to protein family HMM PF04228; hypothetical protein 2746538 5588236 EcE24377A_2755 Escherichia coli E24377A hypothetical protein YP_001463798.1 2745675 R 331111 CDS YP_001463799.1 157155392 5586096 complement(2747083..2747310) 1 NC_009801.1 identified by similarity to GB:AAL23544.1; hypothetical protein 2747310 5586096 EcE24377A_2756 Escherichia coli E24377A hypothetical protein YP_001463799.1 2747083 R 331111 CDS YP_001463800.1 157156219 5589830 complement(2747464..2748177) 1 NC_009801.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 2748177 purC 5589830 purC Escherichia coli E24377A phosphoribosylaminoimidazole-succinocarboxamide synthase YP_001463800.1 2747464 R 331111 CDS YP_001463801.1 157156715 5587200 complement(2748183..2748290) 1 NC_009801.1 identified by glimmer; hypothetical protein 2748290 5587200 EcE24377A_2758 Escherichia coli E24377A hypothetical protein YP_001463801.1 2748183 R 331111 CDS YP_001463802.1 157157892 5586197 complement(2748390..2749424) 1 NC_009801.1 identified by match to protein family HMM PF06804; lipoprotein 2749424 5586197 EcE24377A_2759 Escherichia coli E24377A lipoprotein YP_001463802.1 2748390 R 331111 CDS YP_001463803.1 157158100 5589914 complement(2749441..2750319) 1 NC_009801.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 2750319 dapA 5589914 dapA Escherichia coli E24377A dihydrodipicolinate synthase YP_001463803.1 2749441 R 331111 CDS YP_001463804.1 157158641 5586809 2750399..2751037 1 NC_009801.1 negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2751037 gcvR 5586809 gcvR Escherichia coli E24377A glycine cleavage system transcriptional repressor YP_001463804.1 2750399 D 331111 CDS YP_001463805.1 157159418 5588245 2751037..2751507 1 NC_009801.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2751507 bcp 5588245 bcp Escherichia coli E24377A thioredoxin-dependent thiol peroxidase YP_001463805.1 2751037 D 331111 CDS YP_001463806.1 157156854 5590345 2751760..2752377 1 NC_009801.1 identified by match to protein family HMM PF00037; (Fe-S)-binding protein 2752377 5590345 EcE24377A_2763 Escherichia coli E24377A (Fe-S)-binding protein YP_001463806.1 2751760 D 331111 CDS YP_001463807.1 157156555 5588350 2754405..2755349 1 NC_009801.1 identified by similarity to SP:P16430; similarity to SP:P77858; match to protein family HMM PF00146; hydrogenase-4 subunit C 2755349 hyfC 5588350 hyfC Escherichia coli E24377A hydrogenase-4 subunit C YP_001463807.1 2754405 D 331111 CDS YP_001463808.1 157155069 5587747 2756607..2757257 1 NC_009801.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit 2757257 hyfE 5587747 hyfE Escherichia coli E24377A hydrogenase 4 membrane subunit YP_001463808.1 2756607 D 331111 CDS YP_001463809.1 157157080 5589080 2758838..2760553 1 NC_009801.1 identified by similarity to SP:P77329; match to protein family HMM PF00329; match to protein family HMM PF00346; hydrogenase-4, G subunit 2760553 5589080 EcE24377A_2769 Escherichia coli E24377A hydrogenase-4, G subunit YP_001463809.1 2758838 D 331111 CDS YP_001463810.1 157156396 5589717 2760563..2761108 1 NC_009801.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H 2761108 5589717 EcE24377A_2770 Escherichia coli E24377A hydrogenase 4 subunit H YP_001463810.1 2760563 D 331111 CDS YP_001463811.1 157158565 5589495 2761105..2761863 1 NC_009801.1 identified by similarity to SP:P77668; match to protein family HMM PF01058; hydrogenase-4, I subunit 2761863 5589495 EcE24377A_2771 Escherichia coli E24377A hydrogenase-4, I subunit YP_001463811.1 2761105 D 331111 CDS YP_001463812.1 157159063 5586301 2761856..2762269 1 NC_009801.1 identified by match to protein family HMM PF07450; formate hydrogenlyase maturation protein HycH 2762269 5586301 EcE24377A_2772 Escherichia coli E24377A formate hydrogenlyase maturation protein HycH YP_001463812.1 2761856 D 331111 CDS YP_001463813.1 157157257 5586660 2762299..2764311 1 NC_009801.1 identified by similarity to SP:P19323; match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; formate hydrogenlyase transcriptional activator 2764311 5586660 EcE24377A_2773 Escherichia coli E24377A formate hydrogenlyase transcriptional activator YP_001463813.1 2762299 D 331111 CDS YP_001463814.1 157159160 5589397 2764333..2765181 1 NC_009801.1 inner membrane protein presumed to act as a formate transporter; member of the hyf operon; formate transporter 2765181 focB 5589397 focB Escherichia coli E24377A formate transporter YP_001463814.1 2764333 D 331111 CDS YP_001463815.1 157157181 5587052 complement(2765219..2766280) 1 NC_009801.1 identified by match to protein family HMM PF01594; PerM family permease 2766280 5587052 EcE24377A_2775 Escherichia coli E24377A PerM family permease YP_001463815.1 2765219 R 331111 CDS YP_001463816.1 157157808 5590536 2766493..2767956 1 NC_009801.1 identified by match to protein family HMM PF01435; M48 family peptidase 2767956 5590536 EcE24377A_2776 Escherichia coli E24377A M48 family peptidase YP_001463816.1 2766493 D 331111 CDS YP_001463817.1 157155691 5587274 complement(2768350..2768460) 1 NC_009801.1 identified by glimmer; hypothetical protein 2768460 5587274 EcE24377A_2778 Escherichia coli E24377A hypothetical protein YP_001463817.1 2768350 R 331111 CDS YP_001463818.1 157158460 5590507 complement(2768473..2769219) 1 NC_009801.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 2769219 hda 5590507 hda Escherichia coli E24377A DNA replication initiation factor YP_001463818.1 2768473 R 331111 CDS YP_001463819.1 157157034 5586000 complement(2769269..2770558) 1 NC_009801.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; uracil transporter 2770558 uraA 5586000 uraA Escherichia coli E24377A uracil transporter YP_001463819.1 2769269 R 331111 CDS YP_001463820.1 157155140 5586236 complement(2770644..2771270) 1 NC_009801.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 2771270 upp 5586236 upp Escherichia coli E24377A uracil phosphoribosyltransferase YP_001463820.1 2770644 R 331111 CDS YP_001463821.1 157158807 5589552 2771595..2772632 1 NC_009801.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2772632 purM 5589552 purM Escherichia coli E24377A phosphoribosylaminoimidazole synthetase YP_001463821.1 2771595 D 331111 CDS YP_001463822.1 157157696 5589096 2772632..2773270 1 NC_009801.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2773270 purN 5589096 purN Escherichia coli E24377A phosphoribosylglycinamide formyltransferase YP_001463822.1 2772632 D 331111 CDS YP_001463823.1 157157220 5586637 2773441..2775507 1 NC_009801.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2775507 ppk 5586637 ppk Escherichia coli E24377A polyphosphate kinase YP_001463823.1 2773441 D 331111 CDS YP_001463824.1 157156806 5590187 2775512..2777053 1 NC_009801.1 identified by match to protein family HMM PF02541; exopolyphosphatase 2777053 ppx 5590187 ppx Escherichia coli E24377A exopolyphosphatase YP_001463824.1 2775512 D 331111 CDS YP_001463825.1 157156852 5587562 complement(2777092..2779335) 1 NC_009801.1 identified by match to protein family HMM PF00563; match to protein family HMM PF05231; cyclic diguanylate phosphodiesterase domain-containing protein 2779335 5587562 EcE24377A_2786 Escherichia coli E24377A cyclic diguanylate phosphodiesterase domain-containing protein YP_001463825.1 2777092 R 331111 CDS YP_001463826.1 157156311 5588137 complement(2779517..2779669) 1 NC_009801.1 identified by similarity to GB:AAG57614.1; hypothetical protein 2779669 5588137 EcE24377A_2787 Escherichia coli E24377A hypothetical protein YP_001463826.1 2779517 R 331111 CDS YP_001463827.1 157159199 5587496 2779687..2779878 1 NC_009801.1 identified by similarity to GB:AAL21400.1; hypothetical protein 2779878 5587496 EcE24377A_2788 Escherichia coli E24377A hypothetical protein YP_001463827.1 2779687 D 331111 CDS YP_001463828.1 157156723 5589340 2780192..2780707 1 NC_009801.1 identified by match to protein family HMM PF05433; surface antigen family protein 2780707 5589340 EcE24377A_2789 Escherichia coli E24377A surface antigen family protein YP_001463828.1 2780192 D 331111 CDS YP_001463829.1 157158741 5586932 2780723..2781262 1 NC_009801.1 identified by similarity to SP:P76573; hypothetical protein 2781262 5586932 EcE24377A_2790 Escherichia coli E24377A hypothetical protein YP_001463829.1 2780723 D 331111 CDS YP_001463830.1 157157765 5588110 complement(2781357..2782934) 1 NC_009801.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 2782934 guaA 5588110 guaA Escherichia coli E24377A GMP synthase YP_001463830.1 2781357 R 331111 CDS YP_001463831.1 157155040 5588906 complement(2783003..2784469) 1 NC_009801.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 2784469 guaB 5588906 guaB Escherichia coli E24377A inosine 5'-monophosphate dehydrogenase YP_001463831.1 2783003 R 331111 CDS YP_001463832.1 157155744 5589320 complement(2785998..2786213) 1 NC_009801.1 identified by similarity to GB:AAZ89220.1; match to protein family HMM PF07191; hypothetical protein 2786213 5589320 EcE24377A_2793 Escherichia coli E24377A hypothetical protein YP_001463832.1 2785998 R 331111 CDS YP_001463833.1 157156728 5590580 complement(2786282..2787754) 1 NC_009801.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 2787754 engA 5590580 engA Escherichia coli E24377A GTP-binding protein EngA YP_001463833.1 2786282 R 331111 CDS YP_001463834.1 157155949 5589354 complement(2787872..2789050) 1 NC_009801.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 2789050 5589354 EcE24377A_2796 Escherichia coli E24377A outer membrane protein assembly complex subunit YfgL YP_001463834.1 2787872 R 331111 CDS YP_001463835.1 157158004 5587900 complement(2789061..2789681) 1 NC_009801.1 identified by similarity to GB:AAP83327.1; hypothetical protein 2789681 5587900 EcE24377A_2797 Escherichia coli E24377A hypothetical protein YP_001463835.1 2789061 R 331111 CDS YP_001463836.1 157155202 5590346 complement(2789699..2790973) 1 NC_009801.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 2790973 hisS 5590346 hisS Escherichia coli E24377A histidyl-tRNA synthetase YP_001463836.1 2789699 R 331111 CDS YP_001463837.1 157158896 5587678 complement(2791084..2792202) 1 NC_009801.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2792202 ispG 5587678 ispG Escherichia coli E24377A 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_001463837.1 2791084 R 331111 CDS YP_001463838.1 157155877 5589550 complement(2792229..2793242) 1 NC_009801.1 identified by match to protein family HMM PF01381; cytoskeletal protein RodZ 2793242 5589550 EcE24377A_2800 Escherichia coli E24377A cytoskeletal protein RodZ YP_001463838.1 2792229 R 331111 CDS YP_001463839.1 157157838 5590162 complement(2793527..2794681) 1 NC_009801.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 2794681 5590162 EcE24377A_2801 Escherichia coli E24377A ribosomal RNA large subunit methyltransferase N YP_001463839.1 2793527 R 331111 CDS YP_001463840.1 157157218 5588918 complement(2794831..2795262) 1 NC_009801.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 2795262 ndk 5588918 ndk Escherichia coli E24377A nucleoside diphosphate kinase YP_001463840.1 2794831 R 331111 CDS YP_001463841.1 157158154 5590236 complement(2795411..2797723) 1 NC_009801.1 penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C 2797723 pbpC 5590236 pbpC Escherichia coli E24377A penicillin-binding protein 1C YP_001463841.1 2795411 R 331111 CDS YP_001463842.1 157154935 5589744 complement(2797724..2802685) 1 NC_009801.1 identified by match to protein family HMM PF01835; match to protein family HMM PF07703; alpha-2-macroglobulin 2802685 5589744 EcE24377A_2804 Escherichia coli E24377A alpha-2-macroglobulin YP_001463842.1 2797724 R 331111 CDS YP_001463843.1 157156971 5590039 2802892..2803737 1 NC_009801.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2803737 sseA 5590039 sseA Escherichia coli E24377A 3-mercaptopyruvate sulfurtransferase YP_001463843.1 2802892 D 331111 CDS YP_001463844.1 157158304 5587334 complement(2804230..2805006) 1 NC_009801.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 2805006 sseB 5587334 sseB Escherichia coli E24377A enhanced serine sensitivity protein SseB YP_001463844.1 2804230 R 331111 CDS YP_001463845.1 157155395 5587749 complement(2805148..2806431) 1 NC_009801.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase 2806431 pepB 5587749 pepB Escherichia coli E24377A aminopeptidase YP_001463845.1 2805148 R 331111 CDS YP_001463846.1 157158155 5588582 complement(2806609..2806809) 1 NC_009801.1 identified by similarity to SP:P0C0L9; match to protein family HMM PF04384; match to protein family HMM TIGR03412; hypothetical protein 2806809 iscX 5588582 iscX Escherichia coli E24377A hypothetical protein YP_001463846.1 2806609 R 331111 CDS YP_001463847.1 157158839 5586514 complement(2806821..2807156) 1 NC_009801.1 identified by match to protein family HMM PF00111; match to protein family HMM TIGR02007; (2Fe-2S) ferredoxin 2807156 fdx 5586514 fdx Escherichia coli E24377A (2Fe-2S) ferredoxin YP_001463847.1 2806821 R 331111 CDS YP_001463848.1 157157591 5588883 complement(2807158..2809008) 1 NC_009801.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 2809008 hscA 5588883 hscA Escherichia coli E24377A chaperone protein HscA YP_001463848.1 2807158 R 331111 CDS YP_001463849.1 157158249 5587189 complement(2809025..2809540) 1 NC_009801.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 2809540 hscB 5587189 hscB Escherichia coli E24377A co-chaperone HscB YP_001463849.1 2809025 R 331111 CDS YP_001463850.1 157155994 5587979 complement(2809548..2809664) 1 NC_009801.1 identified by glimmer; hypothetical protein 2809664 5587979 EcE24377A_2812 Escherichia coli E24377A hypothetical protein YP_001463850.1 2809548 R 331111 CDS YP_001463851.1 157156631 5587068 complement(2809636..2809965) 1 NC_009801.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 2809965 iscA 5587068 iscA Escherichia coli E24377A iron-sulfur cluster assembly protein YP_001463851.1 2809636 R 331111 CDS YP_001463852.1 157155593 5586354 complement(2809976..2810362) 1 NC_009801.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01999; scaffold protein 2810362 iscU 5586354 iscU Escherichia coli E24377A scaffold protein YP_001463852.1 2809976 R 331111 CDS YP_001463853.1 157155974 5586952 complement(2810390..2811604) 1 NC_009801.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 2811604 iscS 5586952 iscS Escherichia coli E24377A cysteine desulfurase YP_001463853.1 2810390 R 331111 CDS YP_001463854.1 157158615 5589754 complement(2811716..2812204) 1 NC_009801.1 regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 2812204 iscR 5589754 iscR Escherichia coli E24377A DNA-binding transcriptional regulator IscR YP_001463854.1 2811716 R 331111 CDS YP_001463855.1 157158953 5589450 complement(2812505..2813242) 1 NC_009801.1 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00050; RNA methyltransferase 2813242 5589450 EcE24377A_2817 Escherichia coli E24377A RNA methyltransferase YP_001463855.1 2812505 R 331111 CDS YP_001463856.1 157155322 5587139 2813361..2814164 1 NC_009801.1 identified by similarity to SP:P0ADG4; match to protein family HMM PF00459; inositol monophosphatase 2814164 suhB 5587139 suhB Escherichia coli E24377A inositol monophosphatase YP_001463856.1 2813361 D 331111 CDS YP_001463857.1 157155268 5590675 2814309..2815163 1 NC_009801.1 hypothetical protein 2815163 5590675 EcE24377A_2819 Escherichia coli E24377A hypothetical protein YP_001463857.1 2814309 D 331111 CDS YP_001463858.1 157156379 5587311 2815354..2816634 1 NC_009801.1 identified by match to protein family HMM PF00874; stationary phase inducible protein CsiE 2816634 csiE 5587311 csiE Escherichia coli E24377A stationary phase inducible protein CsiE YP_001463858.1 2815354 D 331111 CDS YP_001463859.1 157156907 5589682 complement(2816626..2817765) 1 NC_009801.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 2817765 hcaT 5589682 hcaT Escherichia coli E24377A 3-phenylpropionic acid transporter YP_001463859.1 2816626 R 331111 CDS YP_001463860.1 157157520 5587894 complement(2817925..2818815) 1 NC_009801.1 activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional regulator HcaR 2818815 hcaR 5587894 hcaR Escherichia coli E24377A DNA-binding transcriptional regulator HcaR YP_001463860.1 2817925 R 331111 CDS YP_001463861.1 157158391 5589475 2820309..2820827 1 NC_009801.1 identified by similarity to SP:Q47140; match to protein family HMM PF00866; 3-phenylpropionate dioxygenase subunit beta 2820827 hcaF 5589475 hcaF Escherichia coli E24377A 3-phenylpropionate dioxygenase subunit beta YP_001463861.1 2820309 D 331111 CDS YP_001463862.1 157154809 5589990 2820827..2821147 1 NC_009801.1 identified by similarity to SP:P0ABW2; match to protein family HMM PF00355; 3-phenylpropionate dioxygenase ferredoxin subunit 2821147 hcaC 5589990 hcaC Escherichia coli E24377A 3-phenylpropionate dioxygenase ferredoxin subunit YP_001463862.1 2820827 D 331111 CDS YP_001463863.1 157158187 5587581 2821144..2821956 1 NC_009801.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase 2821956 hcaB 5587581 hcaB Escherichia coli E24377A 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase YP_001463863.1 2821144 D 331111 CDS YP_001463864.1 157156491 5589044 2821966..2823168 1 NC_009801.1 identified by similarity to SP:P77650; match to protein family HMM PF00070; match to protein family HMM PF07992; phenylpropionate dioxygenase ferredoxin reductase subunit 2823168 hcaD 5589044 hcaD Escherichia coli E24377A phenylpropionate dioxygenase ferredoxin reductase subunit YP_001463864.1 2821966 D 331111 CDS YP_001463865.1 157157627 5588922 2823265..2823687 1 NC_009801.1 identified by match to protein family HMM PF07681; hypothetical protein 2823687 5588922 EcE24377A_2828 Escherichia coli E24377A hypothetical protein YP_001463865.1 2823265 D 331111 CDS YP_001463866.1 157157995 5589540 complement(2823735..2824607) 1 NC_009801.1 identified by match to protein family HMM PF01263; aldose 1-epimerase 2824607 5589540 EcE24377A_2829 Escherichia coli E24377A aldose 1-epimerase YP_001463866.1 2823735 R 331111 CDS YP_001463867.1 157158660 5590616 complement(2824619..2825713) 1 NC_009801.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; zinc-binding dehydrogenase oxidoreductase 2825713 5590616 EcE24377A_2830 Escherichia coli E24377A zinc-binding dehydrogenase oxidoreductase YP_001463867.1 2824619 R 331111 CDS YP_001463868.1 157158445 5587735 complement(2825746..2826744) 1 NC_009801.1 identified by match to protein family HMM PF02653; sugar ABC transporter permease 2826744 5587735 EcE24377A_2831 Escherichia coli E24377A sugar ABC transporter permease YP_001463868.1 2825746 R 331111 CDS YP_001463869.1 157154916 5587652 complement(2826769..2828280) 1 NC_009801.1 yphE; identified by match to protein family HMM PF00005; sugar ABC transporter ATP-binding protein 2828280 5587652 EcE24377A_2832 Escherichia coli E24377A sugar ABC transporter ATP-binding protein YP_001463869.1 2826769 R 331111 CDS YP_001463870.1 157155581 5588395 complement(2828303..2829247) 1 NC_009801.1 identified by match to protein family HMM PF00532; sugar ABC transporter periplasmic sugar-binding protein 2829247 5588395 EcE24377A_2833 Escherichia coli E24377A sugar ABC transporter periplasmic sugar-binding protein YP_001463870.1 2828303 R 331111 CDS YP_001463871.1 157155956 5587308 complement(2829383..2832757) 1 NC_009801.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; hypothetical protein 2832757 5587308 EcE24377A_2834 Escherichia coli E24377A hypothetical protein YP_001463871.1 2829383 R 331111 CDS YP_001463872.1 157156629 5587128 2832782..2833975 1 NC_009801.1 identified by match to protein family HMM PF00480; ROK family protein 2833975 5587128 EcE24377A_2835 Escherichia coli E24377A ROK family protein YP_001463872.1 2832782 D 331111 CDS YP_001463873.1 157157809 5587015 complement(2834039..2835292) 1 NC_009801.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 2835292 glyA 5587015 glyA Escherichia coli E24377A serine hydroxymethyltransferase YP_001463873.1 2834039 R 331111 CDS YP_001463874.1 157157176 5588417 2835620..2836810 1 NC_009801.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2836810 hmp 5588417 hmp Escherichia coli E24377A nitric oxide dioxygenase YP_001463874.1 2835620 D 331111 CDS YP_001463875.1 157158622 5588143 complement(2836855..2837193) 1 NC_009801.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 2837193 glnB 5588143 glnB Escherichia coli E24377A nitrogen regulatory protein P-II 1 YP_001463875.1 2836855 R 331111 CDS YP_001463876.1 157158549 5586224 complement(2837254..2838588) 1 NC_009801.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728; sigma-54 dependent response regulator 2838588 5586224 EcE24377A_2839 Escherichia coli E24377A sigma-54 dependent response regulator YP_001463876.1 2837254 R 331111 CDS YP_001463877.1 157155220 5588572 complement(2838578..2839297) 1 NC_009801.1 hypothetical protein 2839297 5588572 EcE24377A_2840 Escherichia coli E24377A hypothetical protein YP_001463877.1 2838578 R 331111 CDS YP_001463878.1 157159317 5588836 complement(2839456..2840838) 1 NC_009801.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 2840838 5588836 EcE24377A_2841 Escherichia coli E24377A sensor histidine kinase YP_001463878.1 2839456 R 331111 CDS YP_001463879.1 157155948 5590665 complement(2841459..2845346) 1 NC_009801.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 2845346 purL 5590665 purL Escherichia coli E24377A phosphoribosylformylglycinamidine synthase YP_001463879.1 2841459 R 331111 CDS YP_001463880.1 157155869 5587864 2845742..2847160 1 NC_009801.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 2847160 5587864 EcE24377A_2844 Escherichia coli E24377A transglycosylase YP_001463880.1 2845742 D 331111 CDS YP_001463881.1 157157409 5588293 complement(2847157..2847693) 1 NC_009801.1 identified by similarity to SP:P68398; match to protein family HMM PF00383; tRNA-specific adenosine deaminase 2847693 tadA 5588293 tadA Escherichia coli E24377A tRNA-specific adenosine deaminase YP_001463881.1 2847157 R 331111 CDS YP_001463882.1 157156287 5588510 complement(2847718..2848353) 1 NC_009801.1 identified by match to protein family HMM TIGR01545; hypothetical protein 2848353 yhfB 5588510 yhfB Escherichia coli E24377A hypothetical protein YP_001463882.1 2847718 R 331111 CDS YP_001463883.1 157156947 5589788 2848562..2849410 1 NC_009801.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; DNA-binding transcriptional regulator 2849410 5589788 EcE24377A_2846 Escherichia coli E24377A DNA-binding transcriptional regulator YP_001463883.1 2848562 D 331111 CDS YP_001463884.1 157156479 5590249 2849466..2849726 1 NC_009801.1 identified by match to protein family HMM PF00037; 4Fe-4S ferredoxin 2849726 5590249 EcE24377A_2847 Escherichia coli E24377A 4Fe-4S ferredoxin YP_001463884.1 2849466 D 331111 CDS YP_001463885.1 157155906 5589657 complement(2849920..2850018) 1 NC_009801.1 identified by glimmer; hypothetical protein 2850018 5589657 EcE24377A_2848 Escherichia coli E24377A hypothetical protein YP_001463885.1 2849920 R 331111 CDS YP_001463886.1 157155221 5586550 complement(2850420..2850800) 1 NC_009801.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 2850800 acpS 5586550 acpS Escherichia coli E24377A 4'-phosphopantetheinyl transferase YP_001463886.1 2850420 R 331111 CDS YP_001463887.1 157158897 5590452 complement(2850800..2851531) 1 NC_009801.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 2851531 pdxJ 5590452 pdxJ Escherichia coli E24377A pyridoxine 5'-phosphate synthase YP_001463887.1 2850800 R 331111 CDS YP_001463888.1 157158543 5585926 complement(2851543..2852271) 1 NC_009801.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 2852271 recO 5585926 recO Escherichia coli E24377A DNA repair protein RecO YP_001463888.1 2851543 R 331111 CDS YP_001463889.1 157157884 5587943 complement(2852283..2853188) 1 NC_009801.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 2853188 era 5587943 era Escherichia coli E24377A GTP-binding protein Era YP_001463889.1 2852283 R 331111 CDS YP_001463890.1 157157389 5585969 complement(2853185..2853865) 1 NC_009801.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 2853865 rnc 5585969 rnc Escherichia coli E24377A ribonuclease III YP_001463890.1 2853185 R 331111 CDS YP_001463891.1 157156293 5589777 complement(2854137..2855111) 1 NC_009801.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 2855111 lepB 5589777 lepB Escherichia coli E24377A signal peptidase I YP_001463891.1 2854137 R 331111 CDS YP_001463892.1 157158114 5589193 complement(2855127..2856926) 1 NC_009801.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 2856926 lepA 5589193 lepA Escherichia coli E24377A GTP-binding protein LepA YP_001463892.1 2855127 R 331111 CDS YP_001463893.1 157157086 5586176 complement(2857124..2857603) 1 NC_009801.1 involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 2857603 rseC 5586176 rseC Escherichia coli E24377A SoxR reducing system protein RseC YP_001463893.1 2857124 R 331111 CDS YP_001463894.1 157156863 5587495 complement(2857600..2858556) 1 NC_009801.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 2858556 rseB 5587495 rseB Escherichia coli E24377A periplasmic negative regulator of sigmaE YP_001463894.1 2857600 R 331111 CDS YP_001463895.1 157156760 5589516 complement(2858556..2859206) 1 NC_009801.1 identified by match to protein family HMM PF03872; match to protein family HMM PF03873; anti-RNA polymerase sigma factor SigE 2859206 rseA 5589516 rseA Escherichia coli E24377A anti-RNA polymerase sigma factor SigE YP_001463895.1 2858556 R 331111 CDS YP_001463896.1 157156082 5589246 complement(2859239..2859814) 1 NC_009801.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 2859814 rpoE 5589246 rpoE Escherichia coli E24377A RNA polymerase sigma factor RpoE YP_001463896.1 2859239 R 331111 CDS YP_001463897.1 157157796 5589850 complement(2860027..2860134) 1 NC_009801.1 identified by glimmer; hypothetical protein 2860134 5589850 EcE24377A_2860 Escherichia coli E24377A hypothetical protein YP_001463897.1 2860027 R 331111 CDS YP_001463898.1 157158863 5589763 2860222..2861844 1 NC_009801.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2861844 nadB 5589763 nadB Escherichia coli E24377A L-aspartate oxidase YP_001463898.1 2860222 D 331111 CDS YP_001463899.1 157158975 5589589 complement(2861829..2862566) 1 NC_009801.1 identified by match to protein family HMM PF05175; methyltransferase 2862566 5589589 EcE24377A_2861 Escherichia coli E24377A methyltransferase YP_001463899.1 2861829 R 331111 CDS YP_001463900.1 157155812 5589061 2862698..2864032 1 NC_009801.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2864032 srmB 5589061 srmB Escherichia coli E24377A ATP-dependent RNA helicase SrmB YP_001463900.1 2862698 D 331111 CDS YP_001463901.1 157155147 5586495 complement(2864065..2864946) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2864946 5586495 EcE24377A_2864 Escherichia coli E24377A LysR family transcriptional regulator YP_001463901.1 2864065 R 331111 CDS YP_001463902.1 157155051 5589675 2865049..2865636 1 NC_009801.1 identified by match to protein family HMM PF01810; neutral amino-acid efflux protein 2865636 5589675 EcE24377A_2865 Escherichia coli E24377A neutral amino-acid efflux protein YP_001463902.1 2865049 D 331111 CDS YP_001463903.1 157159266 5586198 complement(2865691..2866074) 1 NC_009801.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 2866074 grcA 5586198 grcA Escherichia coli E24377A autonomous glycyl radical cofactor GrcA YP_001463903.1 2865691 R 331111 CDS YP_001463904.1 157155898 5586141 2866379..2867068 1 NC_009801.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2867068 ung 5586141 ung Escherichia coli E24377A uracil-DNA glycosylase YP_001463904.1 2866379 D 331111 CDS YP_001463905.1 157156261 5590392 complement(2867116..2868153) 1 NC_009801.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; methyltransferase 2868153 5590392 EcE24377A_2868 Escherichia coli E24377A methyltransferase YP_001463905.1 2867116 R 331111 CDS YP_001463906.1 157156661 5588576 2868360..2868779 1 NC_009801.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 2 2868779 5588576 EcE24377A_2869 Escherichia coli E24377A thioredoxin 2 YP_001463906.1 2868360 D 331111 CDS YP_001463907.1 157157584 5590686 2868848..2869546 1 NC_009801.1 identified by match to protein family HMM PF03942; DTW domain-containing protein 2869546 5590686 EcE24377A_2870 Escherichia coli E24377A DTW domain-containing protein YP_001463907.1 2868848 D 331111 CDS YP_001463908.1 157157254 5585908 2869578..2872238 1 NC_009801.1 identified by similarity to GB:BAA07751.1; match to protein family HMM PF00583; match to protein family HMM PF02629; CoA-binding domain/acetyltransferase domain-containing protein 2872238 5585908 EcE24377A_2871 Escherichia coli E24377A CoA-binding domain/acetyltransferase domain-containing protein YP_001463908.1 2869578 D 331111 CDS YP_001463909.1 157157759 5588418 2872352..2873707 1 NC_009801.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 2873707 pssA 5588418 pssA Escherichia coli E24377A phosphatidylserine synthase YP_001463909.1 2872352 D 331111 CDS YP_001463910.1 157158495 5586767 2873753..2874076 1 NC_009801.1 hypothetical protein 2874076 5586767 EcE24377A_2874 Escherichia coli E24377A hypothetical protein YP_001463910.1 2873753 D 331111 CDS YP_001463911.1 157159134 5588134 complement(2874073..2875371) 1 NC_009801.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883; alpha-ketoglutarate transporter 2875371 kgtP 5588134 kgtP Escherichia coli E24377A alpha-ketoglutarate transporter YP_001463911.1 2874073 R 331111 CDS YP_001463912.1 157158842 5590143 2881051..2881185 1 NC_009801.1 identified by similarity to GB:AAN81562.1; hypothetical protein 2881185 5590143 EcE24377A_2877 Escherichia coli E24377A hypothetical protein YP_001463912.1 2881051 D 331111 CDS YP_001463913.1 157158232 5589729 complement(2881227..2883800) 1 NC_009801.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; protein disaggregation chaperone 2883800 clpB 5589729 clpB Escherichia coli E24377A protein disaggregation chaperone YP_001463913.1 2881227 R 331111 CDS YP_001463914.1 157156265 5589481 complement(2883930..2884661) 1 NC_009801.1 identified by similarity to PDB:1XAF_A; match to protein family HMM PF02578; match to protein family HMM TIGR00726; hypothetical protein 2884661 5589481 EcE24377A_2879 Escherichia coli E24377A hypothetical protein YP_001463914.1 2883930 R 331111 CDS YP_001463915.1 157156608 5588757 complement(2884658..2885638) 1 NC_009801.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 2885638 rluD 5588757 rluD Escherichia coli E24377A 23S rRNA pseudouridine synthase D YP_001463915.1 2884658 R 331111 CDS YP_001463916.1 157155227 5589011 2885773..2886510 1 NC_009801.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 2886510 5589011 EcE24377A_2881 Escherichia coli E24377A outer membrane protein assembly complex subunit YfiO YP_001463916.1 2885773 D 331111 CDS YP_001463917.1 157155544 5589528 2886781..2887122 1 NC_009801.1 associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 2887122 5589528 EcE24377A_2882 Escherichia coli E24377A translation inhibitor protein RaiA YP_001463917.1 2886781 D 331111 CDS YP_001463918.1 157158544 5586166 2887372..2888532 1 NC_009801.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 2888532 pheA 5586166 pheA Escherichia coli E24377A bifunctional chorismate mutase/prephenate dehydratase YP_001463918.1 2887372 D 331111 CDS YP_001463919.1 157158605 5587944 complement(2888575..2889696) 1 NC_009801.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 2889696 tyrA 5587944 tyrA Escherichia coli E24377A bifunctional chorismate mutase/prephenate dehydrogenase YP_001463919.1 2888575 R 331111 CDS YP_001463920.1 157159289 5586036 complement(2889707..2890777) 1 NC_009801.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 2890777 aroF 5586036 aroF Escherichia coli E24377A phospho-2-dehydro-3-deoxyheptonate aldolase YP_001463920.1 2889707 R 331111 CDS YP_001463921.1 157156238 5588101 2890987..2891352 1 NC_009801.1 hypothetical protein 2891352 5588101 EcE24377A_2886 Escherichia coli E24377A hypothetical protein YP_001463921.1 2890987 D 331111 CDS YP_001463922.1 157156702 5586608 2891502..2892020 1 NC_009801.1 identified by similarity to SP:P64548; hypothetical protein 2892020 5586608 EcE24377A_2887 Escherichia coli E24377A hypothetical protein YP_001463922.1 2891502 D 331111 CDS YP_001463923.1 157157621 5590862 2892013..2893236 1 NC_009801.1 identified by match to protein family HMM PF00672; match to protein family HMM PF00990; match to protein family HMM TIGR00254; hypothetical protein 2893236 5590862 EcE24377A_2888 Escherichia coli E24377A hypothetical protein YP_001463923.1 2892013 D 331111 CDS YP_001463924.1 157158147 5586717 2893252..2893734 1 NC_009801.1 identified by match to protein family HMM PF00691; outer membrane lipoprotein 2893734 5586717 EcE24377A_2889 Escherichia coli E24377A outer membrane lipoprotein YP_001463924.1 2893252 D 331111 CDS YP_001463925.1 157156144 5586613 complement(2893811..2894158) 1 NC_009801.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 2894158 rplS 5586613 rplS Escherichia coli E24377A 50S ribosomal protein L19 YP_001463925.1 2893811 R 331111 CDS YP_001463926.1 157156563 5590093 complement(2894200..2894967) 1 NC_009801.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 2894967 trmD 5590093 trmD Escherichia coli E24377A tRNA (guanine-N(1)-)-methyltransferase YP_001463926.1 2894200 R 331111 CDS YP_001463927.1 157154813 5590195 complement(2894998..2895546) 1 NC_009801.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 2895546 rimM 5590195 rimM Escherichia coli E24377A 16S rRNA-processing protein RimM YP_001463927.1 2894998 R 331111 CDS YP_001463928.1 157156431 5587275 complement(2895565..2895813) 1 NC_009801.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 2895813 rpsP 5587275 rpsP Escherichia coli E24377A 30S ribosomal protein S16 YP_001463928.1 2895565 R 331111 CDS YP_001463929.1 157159233 5590748 complement(2896062..2897423) 1 NC_009801.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 2897423 ffh 5590748 ffh Escherichia coli E24377A signal recognition particle protein YP_001463929.1 2896062 R 331111 CDS YP_001463930.1 157155039 5588105 2897515..2898381 1 NC_009801.1 identified by match to protein family HMM PF01578; cytochrome C assembly protein 2898381 5588105 EcE24377A_2895 Escherichia coli E24377A cytochrome C assembly protein YP_001463930.1 2897515 D 331111 CDS YP_001463931.1 157158162 5590334 2898426..2899688 1 NC_009801.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; hypothetical protein 2899688 5590334 EcE24377A_2896 Escherichia coli E24377A hypothetical protein YP_001463931.1 2898426 D 331111 CDS YP_001463932.1 157157324 5587815 2899811..2900416 1 NC_009801.1 identified by similarity to GB:AAX66587.1; hypothetical protein 2900416 5587815 EcE24377A_2897 Escherichia coli E24377A hypothetical protein YP_001463932.1 2899811 D 331111 CDS YP_001463933.1 157158969 5589579 complement(2900451..2901041) 1 NC_009801.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 2901041 grpE 5589579 grpE Escherichia coli E24377A heat shock protein GrpE YP_001463933.1 2900451 R 331111 CDS YP_001463934.1 157157874 5589917 2901164..2902042 1 NC_009801.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2902042 ppnK 5589917 ppnK Escherichia coli E24377A inorganic polyphosphate/ATP-NAD kinase YP_001463934.1 2901164 D 331111 CDS YP_001463935.1 157157277 5590597 2902128..2903789 1 NC_009801.1 identified by similarity to SP:P05824; match to protein family HMM PF02463; match to protein family HMM TIGR00634; recombination and repair protein 2903789 recN 5590597 recN Escherichia coli E24377A recombination and repair protein YP_001463935.1 2902128 D 331111 CDS YP_001463936.1 157156994 5588983 2903938..2904279 1 NC_009801.1 identified by match to protein family HMM PF04355; hypothetical protein 2904279 5588983 EcE24377A_2901 Escherichia coli E24377A hypothetical protein YP_001463936.1 2903938 D 331111 CDS YP_001463937.1 157156354 5588032 complement(2904341..2904631) 1 NC_009801.1 identified by similarity to SP:P52119; match to protein family HMM PF03658; hypothetical protein 2904631 5588032 EcE24377A_2902 Escherichia coli E24377A hypothetical protein YP_001463937.1 2904341 R 331111 CDS YP_001463938.1 157154724 5588497 complement(2904621..2905058) 1 NC_009801.1 identified by match to protein family HMM PF03364; hypothetical protein 2905058 5588497 EcE24377A_2903 Escherichia coli E24377A hypothetical protein YP_001463938.1 2904621 R 331111 CDS YP_001463939.1 157155286 5589007 2905229..2905711 1 NC_009801.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 2905711 smpB 5589007 smpB Escherichia coli E24377A SsrA-binding protein YP_001463939.1 2905229 D 331111 CDS YP_001463940.1 157158443 5586135 2906374..2907684 1 NC_009801.1 identified by match to protein family HMM PF00589; phage integrase 2907684 5586135 EcE24377A_2905 Escherichia coli E24377A phage integrase YP_001463940.1 2906374 D 331111 CDS YP_001463941.1 157158673 5588398 2907967..2909523 1 NC_009801.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508; resolvase site-specific recombinase 2909523 5588398 EcE24377A_2906 Escherichia coli E24377A resolvase site-specific recombinase YP_001463941.1 2907967 D 331111 CDS YP_001463942.1 157156194 5588533 2909513..2910409 1 NC_009801.1 identified by match to protein family HMM PF02195; ParB family protein 2910409 5588533 EcE24377A_2907 Escherichia coli E24377A ParB family protein YP_001463942.1 2909513 D 331111 CDS YP_001463943.1 157155374 5588555 2910406..2911302 1 NC_009801.1 identified by match to protein family HMM PF07506; repB plasmid partitioning protein 2911302 5588555 EcE24377A_2908 Escherichia coli E24377A repB plasmid partitioning protein YP_001463943.1 2910406 D 331111 CDS YP_001463944.1 157159201 5586861 2912713..2914260 1 NC_009801.1 identified by match to protein family HMM PF02384; N4/N6-methyltransferase 2914260 5586861 EcE24377A_2909 Escherichia coli E24377A N4/N6-methyltransferase YP_001463944.1 2912713 D 331111 CDS YP_001463945.1 157159064 5589342 2914257..2915378 1 NC_009801.1 identified by match to protein family HMM PF01420; type I restriction-modification system subunit S 2915378 5589342 EcE24377A_2910 Escherichia coli E24377A type I restriction-modification system subunit S YP_001463945.1 2914257 D 331111 CDS YP_001463946.1 157158869 5586661 2915437..2918676 1 NC_009801.1 identified by match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM TIGR00348; HsdR family type I site-specific deoxyribonuclease 2918676 5586661 EcE24377A_2911 Escherichia coli E24377A HsdR family type I site-specific deoxyribonuclease YP_001463946.1 2915437 D 331111 CDS YP_001463947.1 157157999 5587314 2919333..2920304 1 NC_009801.1 identified by similarity to GB:AAO54619.1; hypothetical protein 2920304 5587314 EcE24377A_2912 Escherichia coli E24377A hypothetical protein YP_001463947.1 2919333 D 331111 CDS YP_001463948.1 157157246 5586543 2920734..2921720 1 NC_009801.1 identified by glimmer; hypothetical protein 2921720 5586543 EcE24377A_2913 Escherichia coli E24377A hypothetical protein YP_001463948.1 2920734 D 331111 CDS YP_001463949.1 157156980 5590647 2922076..2922516 1 NC_009801.1 identified by glimmer; hypothetical protein 2922516 5590647 EcE24377A_2914 Escherichia coli E24377A hypothetical protein YP_001463949.1 2922076 D 331111 CDS YP_001463950.1 157155196 5590210 2922532..2923476 1 NC_009801.1 identified by glimmer; hypothetical protein 2923476 5590210 EcE24377A_2916 Escherichia coli E24377A hypothetical protein YP_001463950.1 2922532 D 331111 CDS YP_001463951.1 157156825 5587961 complement(2922835..2923002) 1 NC_009801.1 identified by glimmer; hypothetical protein 2923002 5587961 EcE24377A_2915 Escherichia coli E24377A hypothetical protein YP_001463951.1 2922835 R 331111 CDS YP_001463952.1 157156924 5586500 2923654..2924058 1 NC_009801.1 identified by similarity to GB:CAG73977.1; hypothetical protein 2924058 5586500 EcE24377A_2917 Escherichia coli E24377A hypothetical protein YP_001463952.1 2923654 D 331111 CDS YP_001463953.1 157156255 5589965 2924064..2925278 1 NC_009801.1 identified by match to protein family HMM PF03432; relaxase/mobilization nuclease domain-containing protein 2925278 5589965 EcE24377A_2918 Escherichia coli E24377A relaxase/mobilization nuclease domain-containing protein YP_001463953.1 2924064 D 331111 CDS YP_001463954.1 157155697 5590357 2925789..2926175 1 NC_009801.1 lipoprotein 2926175 5590357 EcE24377A_2919 Escherichia coli E24377A lipoprotein YP_001463954.1 2925789 D 331111 CDS YP_001463955.1 157155288 5587915 2926202..2926390 1 NC_009801.1 lipoprotein 2926390 5587915 EcE24377A_2920 Escherichia coli E24377A lipoprotein YP_001463955.1 2926202 D 331111 CDS YP_001463956.1 157155296 5587658 2926464..2927636 1 NC_009801.1 identified by similarity to SP:P15025; match to protein family HMM PF00665; IS21 family transposase 2927636 5587658 EcE24377A_2921 Escherichia coli E24377A IS21 family transposase YP_001463956.1 2926464 D 331111 CDS YP_001463957.1 157158921 5588537 2927636..2928430 1 NC_009801.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein 2928430 5588537 EcE24377A_2922 Escherichia coli E24377A IS21 family transposition helper protein YP_001463957.1 2927636 D 331111 CDS YP_001463958.1 157158393 5588939 complement(2928788..2929213) 1 NC_009801.1 identified by similarity to GB:CAG73974.1; hypothetical protein 2929213 5588939 EcE24377A_2923 Escherichia coli E24377A hypothetical protein YP_001463958.1 2928788 R 331111 CDS YP_001463959.1 157157839 5589758 2930208..2930771 1 NC_009801.1 identified by similarity to GB:AAS55464.1; hypothetical protein 2930771 5589758 EcE24377A_2924 Escherichia coli E24377A hypothetical protein YP_001463959.1 2930208 D 331111 CDS YP_001463960.1 157157844 5589294 complement(2932129..2932983) 1 NC_009801.1 hypothetical protein 2932983 5589294 EcE24377A_2925 Escherichia coli E24377A hypothetical protein YP_001463960.1 2932129 R 331111 CDS YP_001463961.1 157155819 5590756 2933741..2934733 1 NC_009801.1 identified by glimmer; hypothetical protein 2934733 5590756 EcE24377A_2927 Escherichia coli E24377A hypothetical protein YP_001463961.1 2933741 D 331111 CDS YP_001463962.1 157158457 5586115 complement(2933852..2934004) 1 NC_009801.1 identified by glimmer; hypothetical protein 2934004 5586115 EcE24377A_2926 Escherichia coli E24377A hypothetical protein YP_001463962.1 2933852 R 331111 CDS YP_001463963.1 157156062 5587197 2936009..2936974 1 NC_009801.1 identified by similarity to GB:CAG74503.1; hypothetical protein 2936974 5587197 EcE24377A_2928 Escherichia coli E24377A hypothetical protein YP_001463963.1 2936009 D 331111 CDS YP_001463964.1 157158904 5587534 complement(2937655..2937981) 1 NC_009801.1 identified by glimmer; hypothetical protein 2937981 5587534 EcE24377A_2929 Escherichia coli E24377A hypothetical protein YP_001463964.1 2937655 R 331111 CDS YP_001463965.1 157157864 5586850 2940350..2940739 1 NC_009801.1 identified by match to protein family HMM PF01527; IS66 family orf1 2940739 5586850 EcE24377A_2931 Escherichia coli E24377A IS66 family orf1 YP_001463965.1 2940350 D 331111 CDS YP_001463966.1 157157008 5586187 2940736..2941083 1 NC_009801.1 identified by match to protein family HMM PF05717; IS66 family orf2 2941083 5586187 EcE24377A_2932 Escherichia coli E24377A IS66 family orf2 YP_001463966.1 2940736 D 331111 CDS YP_001463967.1 157155024 5589255 2946921..2948762 1 NC_009801.1 identified by match to protein family HMM PF00128; alpha amylase 2948762 5589255 EcE24377A_2937 Escherichia coli E24377A alpha amylase YP_001463967.1 2946921 D 331111 CDS YP_001463968.1 157155822 5589932 2948901..2949173 1 NC_009801.1 identified by similarity to GB:AAP18006.1; hypothetical protein 2949173 5589932 EcE24377A_2938 Escherichia coli E24377A hypothetical protein YP_001463968.1 2948901 D 331111 CDS YP_001463969.1 157159339 5589961 2949509..2950486 1 NC_009801.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 2950486 5589961 EcE24377A_2939 Escherichia coli E24377A hypothetical protein YP_001463969.1 2949509 D 331111 CDS YP_001463970.1 157154793 5589631 2950505..2951773 1 NC_009801.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 2951773 5589631 EcE24377A_2940 Escherichia coli E24377A hydroxyglutarate oxidase YP_001463970.1 2950505 D 331111 CDS YP_001463971.1 157157757 5588281 2951796..2953244 1 NC_009801.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 2953244 gabD 5588281 gabD Escherichia coli E24377A succinate-semialdehyde dehydrogenase I YP_001463971.1 2951796 D 331111 CDS YP_001463972.1 157158550 5587683 2953258..2954538 1 NC_009801.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 2954538 gabT2 5587683 gabT2 Escherichia coli E24377A 4-aminobutyrate aminotransferase YP_001463972.1 2953258 D 331111 CDS YP_001463973.1 157156916 5588573 2954776..2956176 1 NC_009801.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR01773; gamma-aminobutyrate transporter 2956176 gabP 5588573 gabP Escherichia coli E24377A gamma-aminobutyrate transporter YP_001463973.1 2954776 D 331111 CDS YP_001463974.1 157156423 5589196 2956197..2956859 1 NC_009801.1 regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 2956859 csiR 5589196 csiR Escherichia coli E24377A DNA-binding transcriptional regulator CsiR YP_001463974.1 2956197 D 331111 CDS YP_001463975.1 157155690 5588020 complement(2956860..2957309) 1 NC_009801.1 identified by match to protein family HMM PF01476; match to protein family HMM PF04972; LysM domain/BON superfamily protein 2957309 5588020 EcE24377A_2945 Escherichia coli E24377A LysM domain/BON superfamily protein YP_001463975.1 2956860 R 331111 CDS YP_001463976.1 157155295 5590506 complement(2957393..2957551) 1 NC_009801.1 identified by similarity to GB:AAV78517.1; match to protein family HMM PF01679; hypothetical protein 2957551 5590506 EcE24377A_2946 Escherichia coli E24377A hypothetical protein YP_001463976.1 2957393 R 331111 CDS YP_001463977.1 157159108 5589983 2957734..2958033 1 NC_009801.1 identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 2958033 5589983 EcE24377A_2947 Escherichia coli E24377A ArsR family transcriptional regulator YP_001463977.1 2957734 D 331111 CDS YP_001463978.1 157158455 5590858 2958043..2958567 1 NC_009801.1 identified by similarity to SP:P55734; inner membrane protein 2958567 5590858 EcE24377A_2948 Escherichia coli E24377A inner membrane protein YP_001463978.1 2958043 D 331111 CDS YP_001463979.1 157158141 5587195 complement(2958614..2959018) 1 NC_009801.1 identified by similarity to SP:P0ACG3; match to protein family HMM PF00816; DNA binding protein 2959018 stpA 5587195 stpA Escherichia coli E24377A DNA binding protein YP_001463979.1 2958614 R 331111 CDS YP_001463980.1 157157622 5590127 2959432..2959560 1 NC_009801.1 identified by glimmer; hypothetical protein 2959560 5590127 EcE24377A_2950 Escherichia coli E24377A hypothetical protein YP_001463980.1 2959432 D 331111 CDS YP_001463981.1 157154734 5586794 2959686..2960135 1 NC_009801.1 identified by similarity to SP:P64553; match to protein family HMM PF06610; hypothetical protein 2960135 5586794 EcE24377A_2951 Escherichia coli E24377A hypothetical protein YP_001463981.1 2959686 D 331111 CDS YP_001463982.1 157156584 5590257 complement(2960172..2960516) 1 NC_009801.1 hypothetical protein 2960516 5590257 EcE24377A_2952 Escherichia coli E24377A hypothetical protein YP_001463982.1 2960172 R 331111 CDS YP_001463983.1 157158753 5587703 2960668..2960997 1 NC_009801.1 identified by similarity to GB:AAL21687.1; match to protein family HMM PF05957; hypothetical protein 2960997 5587703 EcE24377A_2953 Escherichia coli E24377A hypothetical protein YP_001463983.1 2960668 D 331111 CDS YP_001463984.1 157158453 5586427 2961487..2961897 1 NC_009801.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 2961897 nrdI 5586427 nrdI Escherichia coli E24377A ribonucleotide reductase stimulatory protein YP_001463984.1 2961487 D 331111 CDS YP_001463985.1 157159104 5587360 2961870..2964014 1 NC_009801.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2964014 nrdE 5587360 nrdE Escherichia coli E24377A ribonucleotide-diphosphate reductase subunit alpha YP_001463985.1 2961870 D 331111 CDS YP_001463986.1 157159438 5590028 2964024..2964983 1 NC_009801.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 2964983 nrdF 5590028 nrdF Escherichia coli E24377A ribonucleotide-diphosphate reductase subunit beta YP_001463986.1 2964024 D 331111 CDS YP_001463987.1 157157807 5588742 2965338..2966540 1 NC_009801.1 with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 2966540 proV 5588742 proV Escherichia coli E24377A glycine betaine transporter ATP-binding subunit YP_001463987.1 2965338 D 331111 CDS YP_001463988.1 157159068 5588415 2966533..2967597 1 NC_009801.1 with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 2967597 proW 5588415 proW Escherichia coli E24377A glycine betaine transporter membrane protein YP_001463988.1 2966533 D 331111 CDS YP_001463989.1 157158535 5590520 2967655..2968647 1 NC_009801.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 2968647 proX 5590520 proX Escherichia coli E24377A glycine betaine transporter periplasmic subunit YP_001463989.1 2967655 D 331111 CDS YP_001463990.1 157157730 5587418 complement(2968651..2968746) 1 NC_009801.1 identified by glimmer; hypothetical protein 2968746 5587418 EcE24377A_2961 Escherichia coli E24377A hypothetical protein YP_001463990.1 2968651 R 331111 CDS YP_001463991.1 157157221 5589595 complement(2968679..2968843) 1 NC_009801.1 identified by glimmer; hypothetical protein 2968843 5589595 EcE24377A_2962 Escherichia coli E24377A hypothetical protein YP_001463991.1 2968679 R 331111 CDS YP_001463992.1 157157563 5590188 complement(2968747..2968857) 1 NC_009801.1 identified by glimmer; hypothetical protein 2968857 5590188 EcE24377A_2963 Escherichia coli E24377A hypothetical protein YP_001463992.1 2968747 R 331111 CDS YP_001463993.1 157158676 5586494 2968938..2970122 1 NC_009801.1 identified by match to protein family HMM PF07690; major facilitator family transporter 2970122 5586494 EcE24377A_2964 Escherichia coli E24377A major facilitator family transporter YP_001463993.1 2968938 D 331111 CDS YP_001463994.1 157159128 5586668 2970246..2970983 1 NC_009801.1 identified by match to protein family HMM PF03591; branched chain amino acid ABC transporter 2970983 5586668 EcE24377A_2965 Escherichia coli E24377A branched chain amino acid ABC transporter YP_001463994.1 2970246 D 331111 CDS YP_001463995.1 157157672 5590690 2970973..2971308 1 NC_009801.1 identified by similarity to GB:AAZ89437.1; hypothetical protein 2971308 5590690 EcE24377A_2966 Escherichia coli E24377A hypothetical protein YP_001463995.1 2970973 D 331111 CDS YP_001463996.1 157158204 5588752 2971399..2971929 1 NC_009801.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 2971929 mprA 5588752 mprA Escherichia coli E24377A transcriptional repressor MprA YP_001463996.1 2971399 D 331111 CDS YP_001463997.1 157157777 5589401 2972056..2973228 1 NC_009801.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR00998; multidrug resistance protein A 2973228 emrA 5589401 emrA Escherichia coli E24377A multidrug resistance protein A YP_001463997.1 2972056 D 331111 CDS YP_001463998.1 157155945 5586679 2973245..2974783 1 NC_009801.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; multidrug resistance protein B 2974783 emrB 5586679 emrB Escherichia coli E24377A multidrug resistance protein B YP_001463998.1 2973245 D 331111 CDS YP_001463999.1 157156922 5587279 complement(2974847..2975362) 1 NC_009801.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 2975362 luxS 5587279 luxS Escherichia coli E24377A S-ribosylhomocysteinase YP_001463999.1 2974847 R 331111 CDS YP_001464000.1 157154998 5588400 complement(2975512..2977068) 1 NC_009801.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 2977068 gshA 5588400 gshA Escherichia coli E24377A glutamate--cysteine ligase YP_001464000.1 2975512 R 331111 CDS YP_001464001.1 157155875 5587742 complement(2977141..2977569) 1 NC_009801.1 hypothetical protein 2977569 5587742 EcE24377A_2972 Escherichia coli E24377A hypothetical protein YP_001464001.1 2977141 R 331111 CDS YP_001464002.1 157154797 5589860 complement(2977566..2978132) 1 NC_009801.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 2978132 5589860 EcE24377A_2973 Escherichia coli E24377A fructose-1-phosphatase YP_001464002.1 2977566 R 331111 CDS YP_001464003.1 157158815 5590395 complement(2979455..2979640) 1 NC_009801.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 2979640 csrA 5590395 csrA Escherichia coli E24377A carbon storage regulator YP_001464003.1 2979455 R 331111 CDS YP_001464004.1 157158305 5587731 complement(2979875..2982505) 1 NC_009801.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 2982505 alaS 5587731 alaS Escherichia coli E24377A alanyl-tRNA synthetase YP_001464004.1 2979875 R 331111 CDS YP_001464005.1 157156420 5587750 2982455..2982592 1 NC_009801.1 identified by glimmer; hypothetical protein 2982592 5587750 EcE24377A_2981 Escherichia coli E24377A hypothetical protein YP_001464005.1 2982455 D 331111 CDS YP_001464006.1 157156930 5588337 complement(2982633..2983133) 1 NC_009801.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 2983133 recX 5588337 recX Escherichia coli E24377A recombination regulator RecX YP_001464006.1 2982633 R 331111 CDS YP_001464007.1 157156823 5590486 complement(2983376..2984437) 1 NC_009801.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 2984437 recA 5590486 recA Escherichia coli E24377A recombinase A YP_001464007.1 2983376 R 331111 CDS YP_001464008.1 157156319 5586586 complement(2984517..2985014) 1 NC_009801.1 identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199; competence damage-inducible protein A 2985014 5586586 EcE24377A_2984 Escherichia coli E24377A competence damage-inducible protein A YP_001464008.1 2984517 R 331111 CDS YP_001464009.1 157155764 5588266 complement(2985159..2986244) 1 NC_009801.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 2986244 mltB 5588266 mltB Escherichia coli E24377A murein hydrolase B YP_001464009.1 2985159 R 331111 CDS YP_001464010.1 157155261 5587938 2986500..2987063 1 NC_009801.1 identified by match to protein family HMM PF03608; match to protein family HMM TIGR00821; PTS system glucitol/sorbitol-specific transporter subunit IIC 2987063 srlA 5587938 srlA Escherichia coli E24377A PTS system glucitol/sorbitol-specific transporter subunit IIC YP_001464010.1 2986500 D 331111 CDS YP_001464011.1 157154733 5590868 2987060..2988019 1 NC_009801.1 identified by match to protein family HMM PF03612; match to protein family HMM PF07663; match to protein family HMM TIGR00825; PTS system glucitol/sorbitol-specific transporter subunit IIB 2988019 srlE 5590868 srlE Escherichia coli E24377A PTS system glucitol/sorbitol-specific transporter subunit IIB YP_001464011.1 2987060 D 331111 CDS YP_001464012.1 157156274 5590256 2988030..2988401 1 NC_009801.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 2988401 srlB 5590256 srlB Escherichia coli E24377A PTS system glucitol/sorbitol-specific transporter subunit IIA YP_001464012.1 2988030 D 331111 CDS YP_001464013.1 157155748 5589333 2988406..2989185 1 NC_009801.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 2989185 srlD 5589333 srlD Escherichia coli E24377A sorbitol-6-phosphate dehydrogenase YP_001464013.1 2988406 D 331111 CDS YP_001464014.1 157155150 5586958 2989290..2989649 1 NC_009801.1 regulator for glucitol utilization; DNA-binding transcriptional activator GutM 2989649 gutM 5586958 gutM Escherichia coli E24377A DNA-binding transcriptional activator GutM YP_001464014.1 2989290 D 331111 CDS YP_001464015.1 157159440 5589228 2989716..2990489 1 NC_009801.1 regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 2990489 srlR 5589228 srlR Escherichia coli E24377A DNA-binding transcriptional repressor SrlR YP_001464015.1 2989716 D 331111 CDS YP_001464016.1 157158310 5588744 2990482..2991447 1 NC_009801.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 2991447 gutQ 5588744 gutQ Escherichia coli E24377A D-arabinose 5-phosphate isomerase YP_001464016.1 2990482 D 331111 CDS YP_001464017.1 157157873 5587146 complement(2991444..2992958) 1 NC_009801.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator 2992958 norR 5587146 norR Escherichia coli E24377A anaerobic nitric oxide reductase transcriptional regulator YP_001464017.1 2991444 R 331111 CDS YP_001464018.1 157157407 5590596 2993145..2994584 1 NC_009801.1 detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 2994584 norV 5590596 norV Escherichia coli E24377A anaerobic nitric oxide reductase flavorubredoxin YP_001464018.1 2993145 D 331111 CDS YP_001464019.1 157156682 5588508 2994581..2995714 1 NC_009801.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 2995714 norW 5588508 norW Escherichia coli E24377A nitric oxide reductase YP_001464019.1 2994581 D 331111 CDS YP_001464020.1 157156292 5587796 complement(2995842..2998094) 1 NC_009801.1 identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143; carbamoyltransferase HypF 2998094 hypF 5587796 hypF Escherichia coli E24377A carbamoyltransferase HypF YP_001464020.1 2995842 R 331111 CDS YP_001464021.1 157155890 5590213 complement(2998247..2998774) 1 NC_009801.1 involved in electron transport from formate to hydrogen; electron transport protein HydN 2998774 5590213 EcE24377A_2997 Escherichia coli E24377A electron transport protein HydN YP_001464021.1 2998247 R 331111 CDS YP_001464022.1 157158915 5587445 complement(2998752..2998919) 1 NC_009801.1 identified by glimmer; hypothetical protein 2998919 5587445 EcE24377A_2998 Escherichia coli E24377A hypothetical protein YP_001464022.1 2998752 R 331111 CDS YP_001464023.1 157156958 5589092 complement(2998923..2999936) 1 NC_009801.1 identified by similarity to SP:P24242; match to protein family HMM PF00356; match to protein family HMM PF00532; transcriptional regulator AscG 2999936 ascG 5589092 ascG Escherichia coli E24377A transcriptional regulator AscG YP_001464023.1 2998923 R 331111 CDS YP_001464024.1 157156159 5590656 3000193..3001650 1 NC_009801.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC 3001650 ascF 5590656 ascF Escherichia coli E24377A PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC YP_001464024.1 3000193 D 331111 CDS YP_001464025.1 157158253 5590198 3001659..3003083 1 NC_009801.1 identified by similarity to SP:P24240; match to protein family HMM PF00232; cryptic 6-phospho-beta-glucosidase 3003083 ascB 5590198 ascB Escherichia coli E24377A cryptic 6-phospho-beta-glucosidase YP_001464025.1 3001659 D 331111 CDS YP_001464026.1 157157468 5590382 complement(3003251..3004231) 1 NC_009801.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 3004231 5590382 EcE24377A_3002 Escherichia coli E24377A IS621, transposase YP_001464026.1 3003251 R 331111 CDS YP_001464027.1 157155264 5588099 complement(3004476..3004895) 1 NC_009801.1 identified by match to protein family HMM PF01381; helix-turn-helix DNA-binding domain-containing protein 3004895 5588099 EcE24377A_3003 Escherichia coli E24377A helix-turn-helix DNA-binding domain-containing protein YP_001464027.1 3004476 R 331111 CDS YP_001464028.1 157159408 5590527 complement(3004966..3005721) 1 NC_009801.1 identified by similarity to GB:AAZ89467.1; hypothetical protein 3005721 5590527 EcE24377A_3004 Escherichia coli E24377A hypothetical protein YP_001464028.1 3004966 R 331111 CDS YP_001464029.1 157155343 5588488 complement(3005764..3006234) 1 NC_009801.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease 3006234 hycI 5588488 hycI Escherichia coli E24377A hydrogenase 3 maturation protease YP_001464029.1 3005764 R 331111 CDS YP_001464030.1 157154830 5590013 complement(3006227..3006637) 1 NC_009801.1 identified by match to protein family HMM PF07450; formate hydrogenlyase maturation protein 3006637 5590013 EcE24377A_3006 Escherichia coli E24377A formate hydrogenlyase maturation protein YP_001464030.1 3006227 R 331111 CDS YP_001464031.1 157157238 5586509 complement(3006634..3007401) 1 NC_009801.1 identified by similarity to SP:P16433; match to protein family HMM PF01058; formate hydrogenlyase subunit G 3007401 hycG 5586509 hycG Escherichia coli E24377A formate hydrogenlyase subunit G YP_001464031.1 3006634 R 331111 CDS YP_001464032.1 157157477 5586326 complement(3007401..3007943) 1 NC_009801.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit 3007943 hycF 5586326 hycF Escherichia coli E24377A formate hydrogenlyase complex iron-sulfur subunit YP_001464032.1 3007401 R 331111 CDS YP_001464033.1 157158306 5587579 complement(3007953..3009662) 1 NC_009801.1 identified by similarity to SP:P16431; match to protein family HMM PF00329; match to protein family HMM PF00346; formate hydrogenlyase subunit E 3009662 hycE 5587579 hycE Escherichia coli E24377A formate hydrogenlyase subunit E YP_001464033.1 3007953 R 331111 CDS YP_001464034.1 157158981 5587751 complement(3009680..3010603) 1 NC_009801.1 identified by similarity to SP:P16430; match to protein family HMM PF00146; formate hydrogenlyase subunit D 3010603 hycD 5587751 hycD Escherichia coli E24377A formate hydrogenlyase subunit D YP_001464034.1 3009680 R 331111 CDS YP_001464035.1 157155780 5589278 complement(3010606..3012432) 1 NC_009801.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 3012432 hycC 5589278 hycC Escherichia coli E24377A formate hydrogenlyase subunit 3 YP_001464035.1 3010606 R 331111 CDS YP_001464036.1 157155252 5587645 complement(3012429..3013040) 1 NC_009801.1 identified by similarity to SP:P0AAK1; match to protein family HMM PF00037; formate hydrogenlyase subunit B 3013040 hycB 5587645 hycB Escherichia coli E24377A formate hydrogenlyase subunit B YP_001464036.1 3012429 R 331111 CDS YP_001464037.1 157156901 5589367 complement(3013165..3013626) 1 NC_009801.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA 3013626 hycA 5589367 hycA Escherichia coli E24377A formate hydrogenlyase regulatory protein HycA YP_001464037.1 3013165 R 331111 CDS YP_001464038.1 157156417 5589124 3013838..3014188 1 NC_009801.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 3014188 hypA 5589124 hypA Escherichia coli E24377A hydrogenase nickel incorporation protein YP_001464038.1 3013838 D 331111 CDS YP_001464039.1 157158311 5588845 3014192..3015064 1 NC_009801.1 GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 3015064 hypB 5588845 hypB Escherichia coli E24377A hydrogenase nickel incorporation protein HypB YP_001464039.1 3014192 D 331111 CDS YP_001464040.1 157158164 5587147 3015055..3015327 1 NC_009801.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 3015327 hypC 5587147 hypC Escherichia coli E24377A hydrogenase assembly chaperone YP_001464040.1 3015055 D 331111 CDS YP_001464041.1 157154887 5589000 3015327..3016448 1 NC_009801.1 identified by similarity to SP:P24192; match to protein family HMM PF01924; match to protein family HMM TIGR00075; hydrogenase expression/formation protein HypD 3016448 hypD 5589000 hypD Escherichia coli E24377A hydrogenase expression/formation protein HypD YP_001464041.1 3015327 D 331111 CDS YP_001464042.1 157157601 5590033 3016445..3017455 1 NC_009801.1 identified by similarity to SP:P24193; match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR02124; hydrogenase expression/formation protein HypE 3017455 hypE 5590033 hypE Escherichia coli E24377A hydrogenase expression/formation protein HypE YP_001464042.1 3016445 D 331111 CDS YP_001464043.1 157156943 5589476 3017529..3019607 1 NC_009801.1 identified by similarity to SP:P19323; match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728; formate hydrogenlyase transcriptional activator 3019607 fhlA 5589476 fhlA Escherichia coli E24377A formate hydrogenlyase transcriptional activator YP_001464043.1 3017529 D 331111 CDS YP_001464044.1 157157947 5588037 complement(3019644..3019997) 1 NC_009801.1 identified by similarity to SP:P25728; hypothetical protein 3019997 5588037 EcE24377A_3020 Escherichia coli E24377A hypothetical protein YP_001464044.1 3019644 R 331111 CDS YP_001464045.1 157157273 5590189 complement(3020717..3022696) 1 NC_009801.1 identified by glimmer; hypothetical protein 3022696 5590189 EcE24377A_3021 Escherichia coli E24377A hypothetical protein YP_001464045.1 3020717 R 331111 CDS YP_001464046.1 157154882 5588818 3023045..3023803 1 NC_009801.1 identified by glimmer; hypothetical protein 3023803 5588818 EcE24377A_3022 Escherichia coli E24377A hypothetical protein YP_001464046.1 3023045 D 331111 CDS YP_001464047.1 157159092 5589858 3024015..3025631 1 NC_009801.1 identified by glimmer; hypothetical protein 3025631 5589858 EcE24377A_3023 Escherichia coli E24377A hypothetical protein YP_001464047.1 3024015 D 331111 CDS YP_001464048.1 157156496 5590353 3026474..3026773 1 NC_009801.1 identified by match to protein family HMM PF01527; IS3, transposase orfA 3026773 5590353 EcE24377A_3024 Escherichia coli E24377A IS3, transposase orfA YP_001464048.1 3026474 D 331111 CDS YP_001464049.1 157155856 5587237 3026770..3027636 1 NC_009801.1 identified by similarity to SP:P05822; match to protein family HMM PF00665; IS3, transposase orfB 3027636 5587237 EcE24377A_3025 Escherichia coli E24377A IS3, transposase orfB YP_001464049.1 3026770 D 331111 CDS YP_001464050.1 157156181 5588435 complement(3028075..3030093) 1 NC_009801.1 hypothetical protein 3030093 5588435 EcE24377A_3026 Escherichia coli E24377A hypothetical protein YP_001464050.1 3028075 R 331111 CDS YP_001464051.1 157155065 5586943 complement(3031348..3032808) 1 NC_009801.1 identified by match to protein family HMM PF00589; phage integrase 3032808 5586943 EcE24377A_3028 Escherichia coli E24377A phage integrase YP_001464051.1 3031348 R 331111 CDS YP_001464052.1 157156430 5587055 3032953..3035535 1 NC_009801.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3035535 mutS 5587055 mutS Escherichia coli E24377A DNA mismatch repair protein MutS YP_001464052.1 3032953 D 331111 CDS YP_001464053.1 157156019 5590747 3035641..3036297 1 NC_009801.1 identified by match to protein family HMM PF00149; serine/threonine-specific protein phosphatase 2 3036297 pphB 5590747 pphB Escherichia coli E24377A serine/threonine-specific protein phosphatase 2 YP_001464053.1 3035641 D 331111 CDS YP_001464054.1 157158995 5589894 complement(3036348..3037115) 1 NC_009801.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; DeoR family transcriptional regulator 3037115 5589894 EcE24377A_3032 Escherichia coli E24377A DeoR family transcriptional regulator YP_001464054.1 3036348 R 331111 CDS YP_001464055.1 157158175 5588027 3037311..3038219 1 NC_009801.1 identified by match to protein family HMM PF03446; 6-phosphogluconate dehydrogenase 3038219 5588027 EcE24377A_3033 Escherichia coli E24377A 6-phosphogluconate dehydrogenase YP_001464055.1 3037311 D 331111 CDS YP_001464056.1 157158596 5587096 3038216..3039478 1 NC_009801.1 identified by match to protein family HMM PF07005; hypothetical protein 3039478 5587096 EcE24377A_3034 Escherichia coli E24377A hypothetical protein YP_001464056.1 3038216 D 331111 CDS YP_001464057.1 157159275 5589854 3039475..3040113 1 NC_009801.1 identified by match to protein family HMM PF00596; aldolase 3040113 5589854 EcE24377A_3035 Escherichia coli E24377A aldolase YP_001464057.1 3039475 D 331111 CDS YP_001464058.1 157154894 5586094 3040118..3040894 1 NC_009801.1 identified by match to protein family HMM PF01261; hypothetical protein 3040894 5586094 EcE24377A_3036 Escherichia coli E24377A hypothetical protein YP_001464058.1 3040118 D 331111 CDS YP_001464059.1 157155403 5587634 3040983..3042347 1 NC_009801.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; inner membrane permease YgbN 3042347 5587634 EcE24377A_3037 Escherichia coli E24377A inner membrane permease YgbN YP_001464059.1 3040983 D 331111 CDS YP_001464060.1 157156084 5587355 complement(3042387..3042623) 1 NC_009801.1 identified by similarity to GB:AAY57856.1; 4-hydroxybenzoate decarboxylase subunit D 3042623 kpdD 5587355 kpdD Escherichia coli E24377A 4-hydroxybenzoate decarboxylase subunit D YP_001464060.1 3042387 R 331111 CDS YP_001464061.1 157156336 5590877 complement(3042634..3044061) 1 NC_009801.1 identified by similarity to GB:AAY57855.1; match to protein family HMM PF01977; match to protein family HMM TIGR00148; 4-hydroxybenzoate decarboxylase subunit C 3044061 kpdC 5590877 kpdC Escherichia coli E24377A 4-hydroxybenzoate decarboxylase subunit C YP_001464061.1 3042634 R 331111 CDS YP_001464062.1 157157116 5587557 complement(3044061..3044654) 1 NC_009801.1 identified by similarity to GB:AAY57854.1; match to protein family HMM PF02441; match to protein family HMM TIGR00421; 4-hydroxybenzoate decarboxylase subunit B 3044654 kpdB 5587557 kpdB Escherichia coli E24377A 4-hydroxybenzoate decarboxylase subunit B YP_001464062.1 3044061 R 331111 CDS YP_001464063.1 157158954 5590671 3044801..3045208 1 NC_009801.1 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 3045208 5590671 EcE24377A_3041 Escherichia coli E24377A MarR family transcriptional regulator YP_001464063.1 3044801 D 331111 CDS YP_001464064.1 157157336 5586460 complement(3045329..3046321) 1 NC_009801.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS 3046321 rpoS 5586460 rpoS Escherichia coli E24377A RNA polymerase sigma factor RpoS YP_001464064.1 3045329 R 331111 CDS YP_001464065.1 157158958 5587167 complement(3046384..3047523) 1 NC_009801.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 3047523 nlpD 5587167 nlpD Escherichia coli E24377A lipoprotein NlpD YP_001464065.1 3046384 R 331111 CDS YP_001464066.1 157158360 5586309 complement(3047663..3048289) 1 NC_009801.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 3048289 pcm 5586309 pcm Escherichia coli E24377A protein-L-isoaspartate O-methyltransferase YP_001464066.1 3047663 R 331111 CDS YP_001464067.1 157155771 5590813 complement(3048283..3049044) 1 NC_009801.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 3049044 surE 5590813 surE Escherichia coli E24377A stationary phase survival protein SurE YP_001464067.1 3048283 R 331111 CDS YP_001464068.1 157155259 5586518 complement(3049025..3050074) 1 NC_009801.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 3050074 truD 5586518 truD Escherichia coli E24377A tRNA pseudouridine synthase D YP_001464068.1 3049025 R 331111 CDS YP_001464069.1 157156836 5590724 complement(3050071..3050550) 1 NC_009801.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3050550 ispF 5590724 ispF Escherichia coli E24377A 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_001464069.1 3050071 R 331111 CDS YP_001464070.1 157154915 5586078 complement(3050550..3051260) 1 NC_009801.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3051260 ispD 5586078 ispD Escherichia coli E24377A 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_001464070.1 3050550 R 331111 CDS YP_001464071.1 157156928 5588394 complement(3051279..3051590) 1 NC_009801.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 3051590 ftsB 5588394 ftsB Escherichia coli E24377A cell division protein FtsB YP_001464071.1 3051279 R 331111 CDS YP_001464072.1 157158714 5587236 complement(3051784..3052107) 1 NC_009801.1 identified by similarity to GB:AAG42462.1; hypothetical protein 3052107 5587236 EcE24377A_3050 Escherichia coli E24377A hypothetical protein YP_001464072.1 3051784 R 331111 CDS YP_001464073.1 157155510 5589634 complement(3052157..3052762) 1 NC_009801.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 3052762 cysC 5589634 cysC Escherichia coli E24377A adenylylsulfate kinase YP_001464073.1 3052157 R 331111 CDS YP_001464074.1 157156140 5590781 complement(3052762..3054189) 1 NC_009801.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 3054189 cysN 5590781 cysN Escherichia coli E24377A sulfate adenylyltransferase subunit 1 YP_001464074.1 3052762 R 331111 CDS YP_001464075.1 157158131 5588993 complement(3054191..3055099) 1 NC_009801.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 3055099 cysD 5588993 cysD Escherichia coli E24377A sulfate adenylyltransferase subunit 2 YP_001464075.1 3054191 R 331111 CDS YP_001464076.1 157157125 5587431 3055351..3056388 1 NC_009801.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase 3056388 iap 5587431 iap Escherichia coli E24377A alkaline phosphatase YP_001464076.1 3055351 D 331111 CDS YP_001464077.1 157155405 5589688 complement(3057621..3058541) 1 NC_009801.1 identified by match to protein family HMM TIGR00287; CRISPR-associated Cas1 family protein 3058541 cas1 5589688 cas1 Escherichia coli E24377A CRISPR-associated Cas1 family protein YP_001464077.1 3057621 R 331111 CDS YP_001464078.1 157155574 5587602 complement(3058538..3059188) 1 NC_009801.1 identified by match to protein family HMM PF08798; match to protein family HMM TIGR01907; CRISPR-associated Cse3 family protein 3059188 cse3 5587602 cse3 Escherichia coli E24377A CRISPR-associated Cse3 family protein YP_001464078.1 3058538 R 331111 CDS YP_001464079.1 157156165 5588425 complement(3059170..3059916) 1 NC_009801.1 identified by match to protein family HMM TIGR01868; match to protein family HMM TIGR02593; CRISPR-associated Cas5 family protein 3059916 cas5e 5588425 cas5e Escherichia coli E24377A CRISPR-associated Cas5 family protein YP_001464079.1 3059170 R 331111 CDS YP_001464080.1 157157725 5589843 complement(3059927..3060982) 1 NC_009801.1 identified by match to protein family HMM TIGR01869; CRISPR-associated Cse4 family protein 3060982 cse4 5589843 cse4 Escherichia coli E24377A CRISPR-associated Cse4 family protein YP_001464080.1 3059927 R 331111 CDS YP_001464081.1 157154905 5589047 complement(3060994..3061530) 1 NC_009801.1 identified by match to protein family HMM TIGR02548; CRISPR-associated Cse2 family protein 3061530 cse2 5589047 cse2 Escherichia coli E24377A CRISPR-associated Cse2 family protein YP_001464081.1 3060994 R 331111 CDS YP_001464082.1 157156933 5590399 complement(3061527..3063089) 1 NC_009801.1 identified by match to protein family HMM TIGR02547; CRISPR-associated Cse1 family protein 3063089 cse1 5590399 cse1 Escherichia coli E24377A CRISPR-associated Cse1 family protein YP_001464082.1 3061527 R 331111 CDS YP_001464083.1 157158852 5590841 complement(3063187..3065844) 1 NC_009801.1 identified by match to protein family HMM PF00271; match to protein family HMM TIGR01587; CRISPR-associated helicase Cas3 3065844 cas3 5590841 cas3 Escherichia coli E24377A CRISPR-associated helicase Cas3 YP_001464083.1 3063187 R 331111 CDS YP_001464084.1 157155640 5589881 complement(3066497..3067231) 1 NC_009801.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 3067231 cysH 5589881 cysH Escherichia coli E24377A phosphoadenosine phosphosulfate reductase YP_001464084.1 3066497 R 331111 CDS YP_001464085.1 157159168 5589173 complement(3067305..3069017) 1 NC_009801.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 3069017 cysI 5589173 cysI Escherichia coli E24377A sulfite reductase subunit beta YP_001464085.1 3067305 R 331111 CDS YP_001464086.1 157158512 5587243 complement(3069017..3070816) 1 NC_009801.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 3070816 cysJ 5587243 cysJ Escherichia coli E24377A sulfite reductase subunit alpha YP_001464086.1 3069017 R 331111 CDS YP_001464087.1 157156799 5589497 3071132..3071497 1 NC_009801.1 identified by match to protein family HMM PF01242; match to protein family HMM TIGR00039; match to protein family HMM TIGR03367; queuosine biosynthesis protein QueD 3071497 queD 5589497 queD Escherichia coli E24377A queuosine biosynthesis protein QueD YP_001464087.1 3071132 D 331111 CDS YP_001464088.1 157158429 5587922 3071575..3072846 1 NC_009801.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486; match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase 3072846 5587922 EcE24377A_3068 Escherichia coli E24377A pyridine nucleotide-disulfide oxidoreductase YP_001464088.1 3071575 D 331111 CDS YP_001464089.1 157155612 5589209 3072837..3073097 1 NC_009801.1 ferredoxin 3073097 5589209 EcE24377A_3069 Escherichia coli E24377A ferredoxin YP_001464089.1 3072837 D 331111 CDS YP_001464090.1 157156461 5586064 3073114..3073689 1 NC_009801.1 identified by match to protein family HMM PF04309; glycerol-3-phosphate responsive antiterminator (mRNA-binding), glpp 3073689 5586064 EcE24377A_3070 Escherichia coli E24377A glycerol-3-phosphate responsive antiterminator (mRNA-binding), glpp YP_001464090.1 3073114 D 331111 CDS YP_001464091.1 157159335 5585996 complement(3073837..3074697) 1 NC_009801.1 identified by match to protein family HMM PF00766; electron transfer flavoprotein 3074697 5585996 EcE24377A_3071 Escherichia coli E24377A electron transfer flavoprotein YP_001464091.1 3073837 R 331111 CDS YP_001464092.1 157159131 5589473 complement(3074694..3075473) 1 NC_009801.1 identified by match to protein family HMM PF01012; electron transfer flavoprotein 3075473 5589473 EcE24377A_3072 Escherichia coli E24377A electron transfer flavoprotein YP_001464092.1 3074694 R 331111 CDS YP_001464093.1 157157353 5587636 complement(3075451..3076788) 1 NC_009801.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; major facilitator family transporter 3076788 5587636 EcE24377A_3073 Escherichia coli E24377A major facilitator family transporter YP_001464093.1 3075451 R 331111 CDS YP_001464094.1 157157854 5588298 complement(3076882..3078336) 1 NC_009801.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; FAD binding domain-containing protein 3078336 5588298 EcE24377A_3074 Escherichia coli E24377A FAD binding domain-containing protein YP_001464094.1 3076882 R 331111 CDS YP_001464095.1 157156335 5589410 complement(3078406..3079191) 1 NC_009801.1 ygcW; identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase 3079191 5589410 EcE24377A_3075 Escherichia coli E24377A short chain dehydrogenase/reductase oxidoreductase YP_001464095.1 3078406 R 331111 CDS YP_001464096.1 157158134 5588315 3079510..3080787 1 NC_009801.1 identified by match to protein family HMM PF07690; major facilitator family transporter 3080787 5588315 EcE24377A_3076 Escherichia coli E24377A major facilitator family transporter YP_001464096.1 3079510 D 331111 CDS YP_001464097.1 157155087 5585931 3080814..3082292 1 NC_009801.1 ygcE; identified by match to protein family HMM PF00370; match to protein family HMM PF02782; carbohydrate kinase, FGGY family protein 3082292 5585931 EcE24377A_3077 Escherichia coli E24377A carbohydrate kinase, FGGY family protein YP_001464097.1 3080814 D 331111 CDS YP_001464098.1 157155007 5587585 complement(3084824..3085495) 1 NC_009801.1 hypothetical protein 3085495 5587585 EcE24377A_3080 Escherichia coli E24377A hypothetical protein YP_001464098.1 3084824 R 331111 CDS YP_001464099.1 157155865 5590151 3085634..3085774 1 NC_009801.1 identified by glimmer; hypothetical protein 3085774 5590151 EcE24377A_3081 Escherichia coli E24377A hypothetical protein YP_001464099.1 3085634 D 331111 CDS YP_001464100.1 157158773 5588323 3085788..3086660 1 NC_009801.1 identified by match to protein family HMM PF04536; hypothetical protein 3086660 5588323 EcE24377A_3082 Escherichia coli E24377A hypothetical protein YP_001464100.1 3085788 D 331111 CDS YP_001464101.1 157158911 5587666 complement(3086720..3088018) 1 NC_009801.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 3088018 eno 5587666 eno Escherichia coli E24377A phosphopyruvate hydratase YP_001464101.1 3086720 R 331111 CDS YP_001464102.1 157155633 5590731 complement(3088106..3089743) 1 NC_009801.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 3089743 pyrG 5590731 pyrG Escherichia coli E24377A CTP synthetase YP_001464102.1 3088106 R 331111 CDS YP_001464103.1 157155086 5589760 complement(3089971..3090762) 1 NC_009801.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era; nucleoside triphosphate pyrophosphohydrolase 3090762 mazG 5589760 mazG Escherichia coli E24377A nucleoside triphosphate pyrophosphohydrolase YP_001464103.1 3089971 R 331111 CDS YP_001464104.1 157159087 5588574 complement(3090833..3091168) 1 NC_009801.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA 3091168 chpA 5588574 chpA Escherichia coli E24377A toxin ChpA YP_001464104.1 3090833 R 331111 CDS YP_001464105.1 157158538 5588183 complement(3091168..3091416) 1 NC_009801.1 part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE 3091416 chpR 5588183 chpR Escherichia coli E24377A antitoxin MazE YP_001464105.1 3091168 R 331111 CDS YP_001464106.1 157157706 5587853 complement(3091494..3093728) 1 NC_009801.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase 3093728 relA 5587853 relA Escherichia coli E24377A GDP/GTP pyrophosphokinase YP_001464106.1 3091494 R 331111 CDS YP_001464107.1 157157194 5587757 complement(3093776..3095077) 1 NC_009801.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 3095077 rumA 5587757 rumA Escherichia coli E24377A 23S rRNA 5-methyluridine methyltransferase YP_001464107.1 3093776 R 331111 CDS YP_001464108.1 157159173 5590424 3095134..3097890 1 NC_009801.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3097890 barA 5590424 barA Escherichia coli E24377A hybrid sensory histidine kinase BarA YP_001464108.1 3095134 D 331111 CDS YP_001464109.1 157158551 5587969 complement(3098122..3099462) 1 NC_009801.1 identified by match to protein family HMM PF01188; match to protein family HMM TIGR03247; glucarate dehydratase 3099462 5587969 EcE24377A_3091 Escherichia coli E24377A glucarate dehydratase YP_001464109.1 3098122 R 331111 CDS YP_001464110.1 157157733 5589456 complement(3099483..3100823) 1 NC_009801.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746; glucarate dehydratase 3100823 5589456 EcE24377A_3092 Escherichia coli E24377A glucarate dehydratase YP_001464110.1 3099483 R 331111 CDS YP_001464111.1 157157235 5589645 complement(3100825..3102177) 1 NC_009801.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893; glucarate permease 3102177 gudP 5589645 gudP Escherichia coli E24377A glucarate permease YP_001464111.1 3100825 R 331111 CDS YP_001464112.1 157157821 5587690 complement(3102612..3103061) 1 NC_009801.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 3103061 5587690 EcE24377A_3094 Escherichia coli E24377A flavodoxin YP_001464112.1 3102612 R 331111 CDS YP_001464113.1 157157184 5590184 complement(3103079..3103861) 1 NC_009801.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 3103861 truC 5590184 truC Escherichia coli E24377A tRNA pseudouridine synthase C YP_001464113.1 3103079 R 331111 CDS YP_001464114.1 157157040 5587316 complement(3103861..3104190) 1 NC_009801.1 identified by similarity to SP:Q46919; match to protein family HMM PF04287; hypothetical protein 3104190 5587316 EcE24377A_3096 Escherichia coli E24377A hypothetical protein YP_001464114.1 3103861 R 331111 CDS YP_001464115.1 157156440 5588303 complement(3104812..3105357) 1 NC_009801.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 3105357 5588303 EcE24377A_3097 Escherichia coli E24377A SecY interacting protein Syd YP_001464115.1 3104812 R 331111 CDS YP_001464116.1 157157937 5586719 3105425..3106273 1 NC_009801.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3106273 queF 5586719 queF Escherichia coli E24377A 7-cyano-7-deazaguanine reductase YP_001464116.1 3105425 D 331111 CDS YP_001464117.1 157157259 5590586 complement(3106212..3106304) 1 NC_009801.1 identified by glimmer; hypothetical protein 3106304 5590586 EcE24377A_3098 Escherichia coli E24377A hypothetical protein YP_001464117.1 3106212 R 331111 CDS YP_001464118.1 157155951 5590678 3106385..3107749 1 NC_009801.1 identified by similarity to SP:P0ADS1; match to protein family HMM PF03641; hypothetical protein 3107749 5590678 EcE24377A_3100 Escherichia coli E24377A hypothetical protein YP_001464118.1 3106385 D 331111 CDS YP_001464119.1 157159101 5587902 3108306..3109595 1 NC_009801.1 identified by match to protein family HMM TIGR00814; serine transporter family protein 3109595 5587902 EcE24377A_3101 Escherichia coli E24377A serine transporter family protein YP_001464119.1 3108306 D 331111 CDS YP_001464120.1 157154726 5587927 3109653..3111020 1 NC_009801.1 identified by similarity to SP:P16095; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; L-serine dehydratase 2 3111020 sdaB 5587927 sdaB Escherichia coli E24377A L-serine dehydratase 2 YP_001464120.1 3109653 D 331111 CDS YP_001464121.1 157158560 5587392 3111042..3111887 1 NC_009801.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 3111887 xni 5587392 xni Escherichia coli E24377A exonuclease IX YP_001464121.1 3111042 D 331111 CDS YP_001464122.1 157159169 5589169 complement(3111942..3113090) 1 NC_009801.1 identified by match to protein family HMM PF00465; match to protein family HMM TIGR02638; L-1,2-propanediol oxidoreductase 3113090 fucO 5589169 fucO Escherichia coli E24377A L-1,2-propanediol oxidoreductase YP_001464122.1 3111942 R 331111 CDS YP_001464123.1 157157212 5587466 complement(3113118..3113765) 1 NC_009801.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 3113765 fucA 5587466 fucA Escherichia coli E24377A L-fuculose phosphate aldolase YP_001464123.1 3113118 R 331111 CDS YP_001464124.1 157158254 5586386 3114312..3115628 1 NC_009801.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00885; L-fucose transporter 3115628 fucP 5586386 fucP Escherichia coli E24377A L-fucose transporter YP_001464124.1 3114312 D 331111 CDS YP_001464125.1 157158555 5586819 3115661..3117436 1 NC_009801.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3117436 fucI 5586819 fucI Escherichia coli E24377A L-fucose isomerase YP_001464125.1 3115661 D 331111 CDS YP_001464126.1 157159175 5588857 3117545..3118963 1 NC_009801.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR02628; L-fuculokinase 3118963 fucK 5588857 fucK Escherichia coli E24377A L-fuculokinase YP_001464126.1 3117545 D 331111 CDS YP_001464127.1 157156824 5586695 3118965..3119387 1 NC_009801.1 identified by similarity to SP:P0AEN8; match to protein family HMM PF05025; fucose operon protein FucU 3119387 fucU 5586695 fucU Escherichia coli E24377A fucose operon protein FucU YP_001464127.1 3118965 D 331111 CDS YP_001464128.1 157156369 5586587 3119445..3120176 1 NC_009801.1 regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 3120176 fucR 5586587 fucR Escherichia coli E24377A DNA-binding transcriptional activator FucR YP_001464128.1 3119445 D 331111 CDS YP_001464129.1 157155644 5589736 complement(3119568..3119681) 1 NC_009801.1 identified by glimmer; hypothetical protein 3119681 5589736 EcE24377A_3110 Escherichia coli E24377A hypothetical protein YP_001464129.1 3119568 R 331111 CDS YP_001464130.1 157157061 5588645 complement(3120220..3121320) 1 NC_009801.1 RNA 2'-O-ribose methyltransferase 3121320 5588645 EcE24377A_3112 Escherichia coli E24377A RNA 2'-O-ribose methyltransferase YP_001464130.1 3120220 R 331111 CDS YP_001464131.1 157156642 5589380 complement(3121313..3121708) 1 NC_009801.1 identified by match to protein family HMM PF04241; hypothetical protein 3121708 5589380 EcE24377A_3113 Escherichia coli E24377A hypothetical protein YP_001464131.1 3121313 R 331111 CDS YP_001464132.1 157155797 5587898 complement(3121727..3122644) 1 NC_009801.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 3122644 gcvA 5587898 gcvA Escherichia coli E24377A DNA-binding transcriptional activator GcvA YP_001464132.1 3121727 R 331111 CDS YP_001464133.1 157157648 5588287 complement(3122995..3123222) 1 NC_009801.1 identified by match to protein family HMM PF06004; lipoprotein 3123222 5588287 EcE24377A_3115 Escherichia coli E24377A lipoprotein YP_001464133.1 3122995 R 331111 CDS YP_001464134.1 157156888 5587381 3123414..3124619 1 NC_009801.1 identified by match to protein family HMM PF00266; match to protein family HMM TIGR03392; cysteine sulfinate desulfinase 3124619 csdA 5587381 csdA Escherichia coli E24377A cysteine sulfinate desulfinase YP_001464134.1 3123414 D 331111 CDS YP_001464135.1 157158642 5588662 3124619..3125062 1 NC_009801.1 identified by similarity to SP:P0AGF2; match to protein family HMM PF02657; match to protein family HMM TIGR03391; cysteine desulfuration protein CsdE 3125062 csdE 5588662 csdE Escherichia coli E24377A cysteine desulfuration protein CsdE YP_001464135.1 3124619 D 331111 CDS YP_001464136.1 157158275 5588246 complement(3125113..3125919) 1 NC_009801.1 identified by match to protein family HMM PF00899; ThiF family protein 3125919 5588246 EcE24377A_3118 Escherichia coli E24377A ThiF family protein YP_001464136.1 3125113 R 331111 CDS YP_001464137.1 157155153 5586467 complement(3125996..3127093) 1 NC_009801.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 3127093 mltA 5586467 mltA Escherichia coli E24377A murein transglycosylase A YP_001464137.1 3125996 R 331111 CDS YP_001464138.1 157154801 5589566 3128230..3128730 1 NC_009801.1 identified by similarity to GB:AAN81830.1; match to protein family HMM PF05591; match to protein family HMM TIGR03358; hypothetical protein 3128730 5589566 EcE24377A_3123 Escherichia coli E24377A hypothetical protein YP_001464138.1 3128230 D 331111 CDS YP_001464139.1 157155143 5587803 3128789..3130327 1 NC_009801.1 identified by match to protein family HMM PF05943; match to protein family HMM TIGR03355; hypothetical protein 3130327 5587803 EcE24377A_3124 Escherichia coli E24377A hypothetical protein YP_001464139.1 3128789 D 331111 CDS YP_001464140.1 157155664 5589163 3130345..3131682 1 NC_009801.1 identified by similarity to GB:AAN81832.1; match to protein family HMM PF05936; match to protein family HMM TIGR03353; hypothetical protein 3131682 5589163 EcE24377A_3125 Escherichia coli E24377A hypothetical protein YP_001464140.1 3130345 D 331111 CDS YP_001464141.1 157156380 5587744 3131679..3132344 1 NC_009801.1 identified by match to protein family HMM TIGR03349; DotU family type IV/VI secretion system protein 3132344 5587744 EcE24377A_3126 Escherichia coli E24377A DotU family type IV/VI secretion system protein YP_001464141.1 3131679 D 331111 CDS YP_001464142.1 157156833 5589683 3132357..3134009 1 NC_009801.1 identified by match to protein family HMM PF00691; OmpA domain-containing protein 3134009 5589683 EcE24377A_3127 Escherichia coli E24377A OmpA domain-containing protein YP_001464142.1 3132357 D 331111 CDS YP_001464143.1 157157465 5586414 3134067..3134558 1 NC_009801.1 identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344; hypothetical protein 3134558 5586414 EcE24377A_3128 Escherichia coli E24377A hypothetical protein YP_001464143.1 3134067 D 331111 CDS YP_001464144.1 157155408 5587448 3134749..3137394 1 NC_009801.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03345; ClpA/ClpB family protein 3137394 5587448 EcE24377A_3129 Escherichia coli E24377A ClpA/ClpB family protein YP_001464144.1 3134749 D 331111 CDS YP_001464145.1 157158477 5589797 3137406..3139913 1 NC_009801.1 identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361; ImpA family type VI secretion-associated protein 3139913 5589797 EcE24377A_3130 Escherichia coli E24377A ImpA family type VI secretion-associated protein YP_001464145.1 3137406 D 331111 CDS YP_001464146.1 157158177 5586998 3139935..3140537 1 NC_009801.1 hypothetical protein 3140537 5586998 EcE24377A_3131 Escherichia coli E24377A hypothetical protein YP_001464146.1 3139935 D 331111 CDS YP_001464147.1 157157411 5587394 3140539..3141090 1 NC_009801.1 hypothetical protein 3141090 5587394 EcE24377A_3132 Escherichia coli E24377A hypothetical protein YP_001464147.1 3140539 D 331111 CDS YP_001464148.1 157159449 5588905 3141298..3141681 1 NC_009801.1 identified by match to protein family HMM TIGR03352; type VI secretion lipoprotein 3141681 5588905 EcE24377A_3133 Escherichia coli E24377A type VI secretion lipoprotein YP_001464148.1 3141298 D 331111 CDS YP_001464149.1 157158774 5586724 3141685..3142113 1 NC_009801.1 identified by similarity to GB:AAN81847.1; match to protein family HMM PF04965; match to protein family HMM TIGR03357; hypothetical protein 3142113 5586724 EcE24377A_3134 Escherichia coli E24377A hypothetical protein YP_001464149.1 3141685 D 331111 CDS YP_001464150.1 157156697 5586337 3142113..3143489 1 NC_009801.1 identified by match to protein family HMM PF06812; ImpA-related N-terminal domain-containing protein 3143489 5586337 EcE24377A_3135 Escherichia coli E24377A ImpA-related N-terminal domain-containing protein YP_001464150.1 3142113 D 331111 CDS YP_001464151.1 157158496 5586980 3143554..3144102 1 NC_009801.1 identified by glimmer; hypothetical protein 3144102 5586980 EcE24377A_3136 Escherichia coli E24377A hypothetical protein YP_001464151.1 3143554 D 331111 CDS YP_001464152.1 157157803 5588135 complement(3144448..3145701) 1 NC_009801.1 identified by similarity to SP:P63883; match to protein family HMM PF01520; match to protein family HMM TIGR01409; N-acetylmuramoyl-L-alanine amidase 3145701 amiC 5588135 amiC Escherichia coli E24377A N-acetylmuramoyl-L-alanine amidase YP_001464152.1 3144448 R 331111 CDS YP_001464153.1 157156402 5590064 3145933..3147264 1 NC_009801.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3147264 argA 5590064 argA Escherichia coli E24377A N-acetylglutamate synthase YP_001464153.1 3145933 D 331111 CDS YP_001464154.1 157155694 5589534 complement(3147326..3149152) 1 NC_009801.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha 3149152 recD 5589534 recD Escherichia coli E24377A exonuclease V subunit alpha YP_001464154.1 3147326 R 331111 CDS YP_001464155.1 157157251 5590490 complement(3149152..3152694) 1 NC_009801.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta 3152694 recB 5590490 recB Escherichia coli E24377A exonuclease V subunit beta YP_001464155.1 3149152 R 331111 CDS YP_001464156.1 157156589 5588723 complement(3152687..3155575) 1 NC_009801.1 identified by similarity to SP:P05458; match to protein family HMM PF00675; match to protein family HMM PF05193; protease III 3155575 ptrA 5588723 ptrA Escherichia coli E24377A protease III YP_001464156.1 3152687 R 331111 CDS YP_001464157.1 157158584 5587054 complement(3155751..3159119) 1 NC_009801.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 3159119 recC 5587054 recC Escherichia coli E24377A exonuclease V subunit gamma YP_001464157.1 3155751 R 331111 CDS YP_001464158.1 157157836 5588621 complement(3159132..3159455) 1 NC_009801.1 identified by similarity to SP:P08372; match to protein family HMM PF07963; match to protein family HMM TIGR02532; hypothetical protein 3159455 ppdC 5588621 ppdC Escherichia coli E24377A hypothetical protein YP_001464158.1 3159132 R 331111 CDS YP_001464159.1 157155732 5588726 complement(3159440..3159847) 1 NC_009801.1 identified by similarity to SP:P08370; hypothetical protein 3159847 5588726 EcE24377A_3144 Escherichia coli E24377A hypothetical protein YP_001464159.1 3159440 R 331111 CDS YP_001464160.1 157158679 5590794 complement(3159844..3160407) 1 NC_009801.1 identified by similarity to SP:P08371; match to protein family HMM PF07963; match to protein family HMM TIGR02532; hypothetical protein 3160407 ppdB 5590794 ppdB Escherichia coli E24377A hypothetical protein YP_001464160.1 3159844 R 331111 CDS YP_001464161.1 157158210 5590287 complement(3160398..3160868) 1 NC_009801.1 identified by similarity to SP:P33554; match to protein family HMM PF07963; match to protein family HMM TIGR02532; hypothetical protein 3160868 ppdA 5590287 ppdA Escherichia coli E24377A hypothetical protein YP_001464161.1 3160398 R 331111 CDS YP_001464162.1 157156066 5586350 complement(3161053..3161847) 1 NC_009801.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 3161847 thyA 5586350 thyA Escherichia coli E24377A thymidylate synthase YP_001464162.1 3161053 R 331111 CDS YP_001464163.1 157158935 5590133 complement(3161854..3162729) 1 NC_009801.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 3162729 lgt 5590133 lgt Escherichia coli E24377A prolipoprotein diacylglyceryl transferase YP_001464163.1 3161854 R 331111 CDS YP_001464164.1 157157288 5586216 complement(3162880..3165126) 1 NC_009801.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain 3165126 ptsP 5586216 ptsP Escherichia coli E24377A fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain YP_001464164.1 3162880 R 331111 CDS YP_001464165.1 157155107 5586298 complement(3165139..3165669) 1 NC_009801.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 3165669 nudH 5586298 nudH Escherichia coli E24377A dinucleoside polyphosphate hydrolase YP_001464165.1 3165139 R 331111 CDS YP_001464166.1 157155642 5587996 3166354..3167043 1 NC_009801.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3167043 mutH 5587996 mutH Escherichia coli E24377A DNA mismatch repair protein YP_001464166.1 3166354 D 331111 CDS YP_001464167.1 157156487 5588643 3167112..3167825 1 NC_009801.1 identified by match to protein family HMM PF03741; TerC family integral membrane protein 3167825 5588643 EcE24377A_3152 Escherichia coli E24377A TerC family integral membrane protein YP_001464167.1 3167112 D 331111 CDS YP_001464168.1 157156973 5589249 3167963..3168181 1 NC_009801.1 identified by similarity to GB:AAV78717.1; match to protein family HMM PF06004; lipoprotein 3168181 5589249 EcE24377A_3153 Escherichia coli E24377A lipoprotein YP_001464168.1 3167963 D 331111 CDS YP_001464169.1 157154848 5589254 3168289..3169329 1 NC_009801.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo-keto reductase 3169329 tas 5589254 tas Escherichia coli E24377A aldo-keto reductase YP_001464169.1 3168289 D 331111 CDS YP_001464170.1 157159106 5589518 complement(3169361..3170524) 1 NC_009801.1 identified by match to protein family HMM PF07690; lysophospholipid transporter LplT 3170524 lplT 5589518 lplT Escherichia coli E24377A lysophospholipid transporter LplT YP_001464170.1 3169361 R 331111 CDS YP_001464171.1 157155604 5590030 complement(3170547..3172706) 1 NC_009801.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 3172706 aas 5590030 aas Escherichia coli E24377A bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase YP_001464171.1 3170547 R 331111 CDS YP_001464172.1 157155079 5589576 3173292..3174323 1 NC_009801.1 controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3174323 galR 5589576 galR Escherichia coli E24377A DNA-binding transcriptional regulator GalR YP_001464172.1 3173292 D 331111 CDS YP_001464173.1 157157020 5588244 complement(3174330..3175592) 1 NC_009801.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 3175592 lysA 5588244 lysA Escherichia coli E24377A diaminopimelate decarboxylase YP_001464173.1 3174330 R 331111 CDS YP_001464174.1 157157128 5586575 3175714..3176649 1 NC_009801.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 3176649 lysR 5586575 lysR Escherichia coli E24377A LysR family transcriptional regulator YP_001464174.1 3175714 D 331111 CDS YP_001464175.1 157156519 5586124 complement(3176355..3176453) 1 NC_009801.1 identified by glimmer; hypothetical protein 3176453 5586124 EcE24377A_3159 Escherichia coli E24377A hypothetical protein YP_001464175.1 3176355 R 331111 CDS YP_001464176.1 157157912 5587021 complement(3176636..3177328) 1 NC_009801.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035; racemase 3177328 5587021 EcE24377A_3160 Escherichia coli E24377A racemase YP_001464176.1 3176636 R 331111 CDS YP_001464177.1 157159072 5588916 complement(3177457..3178875) 1 NC_009801.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879; arabinose-proton symporter 3178875 araE 5588916 araE Escherichia coli E24377A arabinose-proton symporter YP_001464177.1 3177457 R 331111 CDS YP_001464178.1 157156022 5588424 complement(3178826..3178924) 1 NC_009801.1 identified by glimmer; hypothetical protein 3178924 5588424 EcE24377A_3163 Escherichia coli E24377A hypothetical protein YP_001464178.1 3178826 R 331111 CDS YP_001464179.1 157158009 5586440 complement(3179190..3179951) 1 NC_009801.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase 3179951 kduD 5586440 kduD Escherichia coli E24377A 2-deoxy-D-gluconate 3-dehydrogenase YP_001464179.1 3179190 R 331111 CDS YP_001464180.1 157156429 5588391 complement(3179981..3180817) 1 NC_009801.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase 3180817 5588391 EcE24377A_3165 Escherichia coli E24377A 5-keto-4-deoxyuronate isomerase YP_001464180.1 3179981 R 331111 CDS YP_001464181.1 157157240 5586712 complement(3181104..3182285) 1 NC_009801.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 3182285 5586712 EcE24377A_3166 Escherichia coli E24377A acetyl-CoA acetyltransferase YP_001464181.1 3181104 R 331111 CDS YP_001464182.1 157157731 5587920 3182540..3183769 1 NC_009801.1 identified by match to protein family HMM PF01490; match to protein family HMM TIGR00814; serine transporter family protein 3183769 5587920 EcE24377A_3167 Escherichia coli E24377A serine transporter family protein YP_001464182.1 3182540 D 331111 CDS YP_001464183.1 157158553 5589596 3184169..3184861 1 NC_009801.1 identified by similarity to GB:AAZ89600.1; hypothetical protein 3184861 5589596 EcE24377A_3168 Escherichia coli E24377A hypothetical protein YP_001464183.1 3184169 D 331111 CDS YP_001464184.1 157159044 5588855 3185195..3186004 1 NC_009801.1 identified by match to protein family HMM PF00486; transcriptional regulatory protein, C terminal 3186004 5588855 EcE24377A_3169 Escherichia coli E24377A transcriptional regulatory protein, C terminal YP_001464184.1 3185195 D 331111 CDS YP_001464185.1 157155095 5587931 3186087..3186479 1 NC_009801.1 hypothetical protein 3186479 5587931 EcE24377A_3170 Escherichia coli E24377A hypothetical protein YP_001464185.1 3186087 D 331111 CDS YP_001464186.1 157155783 5588773 complement(3186512..3186652) 1 NC_009801.1 identified by glimmer; hypothetical protein 3186652 5588773 EcE24377A_3171 Escherichia coli E24377A hypothetical protein YP_001464186.1 3186512 R 331111 CDS YP_001464187.1 157156590 5588192 3187962..3188453 1 NC_009801.1 identified by match to protein family HMM PF07720; hypothetical protein 3188453 5588192 EcE24377A_3172 Escherichia coli E24377A hypothetical protein YP_001464187.1 3187962 D 331111 CDS YP_001464188.1 157159462 5589372 3188788..3190164 1 NC_009801.1 identified by match to protein family HMM PF00486; match to protein family HMM PF07719; transcriptional regulator 3190164 5589372 EcE24377A_3173 Escherichia coli E24377A transcriptional regulator YP_001464188.1 3188788 D 331111 CDS YP_001464189.1 157158277 5587119 complement(3190617..3190835) 1 NC_009801.1 identified by glimmer; hypothetical protein 3190835 5587119 EcE24377A_3174 Escherichia coli E24377A hypothetical protein YP_001464189.1 3190617 R 331111 CDS YP_001464190.1 157157590 5588728 complement(3191153..3191599) 1 NC_009801.1 identified by match to protein family HMM PF00196; LuxR family transcriptional regulator 3191599 5588728 EcE24377A_3175 Escherichia coli E24377A LuxR family transcriptional regulator YP_001464190.1 3191153 R 331111 CDS YP_001464191.1 157158255 5587188 complement(3192006..3192437) 1 NC_009801.1 identified by similarity to GB:AAA83039.1; hypothetical protein 3192437 5587188 EcE24377A_3176 Escherichia coli E24377A hypothetical protein YP_001464191.1 3192006 R 331111 CDS YP_001464192.1 157157566 5586820 complement(3193251..3193985) 1 NC_009801.1 identified by match to protein family HMM PF01514; match to protein family HMM TIGR02544; type III secretion apparatus lipoprotein EprK 3193985 eprK 5586820 eprK Escherichia coli E24377A type III secretion apparatus lipoprotein EprK YP_001464192.1 3193251 R 331111 CDS YP_001464193.1 157155332 5586919 complement(3194586..3195767) 1 NC_009801.1 identified by match to protein family HMM TIGR02554; type III secretion apparatus protein EprH 3195767 eprH 5586919 eprH Escherichia coli E24377A type III secretion apparatus protein EprH YP_001464193.1 3194586 R 331111 CDS YP_001464194.1 157159225 5588784 complement(3197269..3198000) 1 NC_009801.1 identified by similarity to SP:P40727; match to protein family HMM PF01312; FlhB/HrpN/YscU/SpaS family protein 3198000 5588784 EcE24377A_3181 Escherichia coli E24377A FlhB/HrpN/YscU/SpaS family protein YP_001464194.1 3197269 R 331111 CDS YP_001464195.1 157158728 5586533 complement(3198009..3198776) 1 NC_009801.1 identified by similarity to GB:BAB60840.1; match to protein family HMM PF01311; match to protein family HMM TIGR01401; type III secretion apparatus protein EpaR 3198776 epaR 5586533 epaR Escherichia coli E24377A type III secretion apparatus protein EpaR YP_001464195.1 3198009 R 331111 CDS YP_001464196.1 157158179 5587638 complement(3198778..3199038) 1 NC_009801.1 identified by similarity to GB:AAZ31292.1; match to protein family HMM PF01313; match to protein family HMM TIGR01403; type III secretion apparatus protein EpaQ 3199038 epaQ 5587638 epaQ Escherichia coli E24377A type III secretion apparatus protein EpaQ YP_001464196.1 3198778 R 331111 CDS YP_001464197.1 157159039 5586522 complement(3199048..3199713) 1 NC_009801.1 part of a type III secretory system probably involved in invasion into eukaryotic cells; surface presentation of antigens protein SpaP 3199713 spaP 5586522 spaP Escherichia coli E24377A surface presentation of antigens protein SpaP YP_001464197.1 3199048 R 331111 CDS YP_001464198.1 157154771 5589728 complement(3199703..3200275) 1 NC_009801.1 identified by match to protein family HMM PF01052; match to protein family HMM TIGR02551; type III secretion apparatus protein EpaO2 3200275 epaO2 5589728 epaO2 Escherichia coli E24377A type III secretion apparatus protein EpaO2 YP_001464198.1 3199703 R 331111 CDS YP_001464199.1 157158665 5589492 complement(3200650..3200748) 1 NC_009801.1 identified by similarity to GB:BAB37150.1; type III secretion apparatus protein, truncation 3200748 5589492 EcE24377A_3186 Escherichia coli E24377A type III secretion apparatus protein, truncation YP_001464199.1 3200650 R 331111 CDS YP_001464200.1 157159245 5587286 complement(3200782..3202434) 1 NC_009801.1 hypothetical protein 3202434 5587286 EcE24377A_3187 Escherichia coli E24377A hypothetical protein YP_001464200.1 3200782 R 331111 CDS YP_001464201.1 157157652 5586455 3202458..3202568 1 NC_009801.1 identified by glimmer; hypothetical protein 3202568 5586455 EcE24377A_3188 Escherichia coli E24377A hypothetical protein YP_001464201.1 3202458 D 331111 CDS YP_001464202.1 157158148 5590147 complement(3202778..3203533) 1 NC_009801.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551; M23B family peptidase 3203533 5590147 EcE24377A_3190 Escherichia coli E24377A M23B family peptidase YP_001464202.1 3202778 R 331111 CDS YP_001464203.1 157156011 5586614 3203948..3206245 1 NC_009801.1 molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3206245 xdhA 5586614 xdhA Escherichia coli E24377A xanthine dehydrogenase subunit XdhA YP_001464203.1 3203948 D 331111 CDS YP_001464204.1 157156683 5587358 3206256..3207134 1 NC_009801.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3207134 xdhB 5587358 xdhB Escherichia coli E24377A xanthine dehydrogenase subunit XdhB YP_001464204.1 3206256 D 331111 CDS YP_001464205.1 157159435 5587797 3207131..3207610 1 NC_009801.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3207610 xdhC 5587797 xdhC Escherichia coli E24377A xanthine dehydrogenase subunit XdhC YP_001464205.1 3207131 D 331111 CDS YP_001464206.1 157155317 5587617 complement(3207650..3209428) 1 NC_009801.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; sigma-54 dependent trancsriptional regulator 3209428 5587617 EcE24377A_3194 Escherichia coli E24377A sigma-54 dependent trancsriptional regulator YP_001464206.1 3207650 R 331111 CDS YP_001464207.1 157157961 5590502 3209904..3211094 1 NC_009801.1 ygeW; identified by match to protein family HMM PF00185; match to protein family HMM PF02729; aspartate/ornithine carbamoyltransferase 3211094 5590502 EcE24377A_3195 Escherichia coli E24377A aspartate/ornithine carbamoyltransferase YP_001464207.1 3209904 D 331111 CDS YP_001464208.1 157157279 5590157 3211152..3212348 1 NC_009801.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3212348 5590157 EcE24377A_3196 Escherichia coli E24377A diaminopropionate ammonia-lyase YP_001464208.1 3211152 D 331111 CDS YP_001464209.1 157154874 5589722 3212406..3213617 1 NC_009801.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3213617 5589722 EcE24377A_3197 Escherichia coli E24377A peptidase YP_001464209.1 3212406 D 331111 CDS YP_001464210.1 157158964 5587404 3213670..3215055 1 NC_009801.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3215055 hyuA 5587404 hyuA Escherichia coli E24377A phenylhydantoinase YP_001464210.1 3213670 D 331111 CDS YP_001464211.1 157155883 5589941 3215103..3216035 1 NC_009801.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3216035 5589941 EcE24377A_3199 Escherichia coli E24377A carbamate kinase YP_001464211.1 3215103 D 331111 CDS YP_001464212.1 157155346 5587965 complement(3216076..3217701) 1 NC_009801.1 identified by match to protein family HMM PF00364; match to protein family HMM PF02625; match to protein family HMM TIGR03309; xanthine dehydrogenase accessory factor 3217701 5587965 EcE24377A_3200 Escherichia coli E24377A xanthine dehydrogenase accessory factor YP_001464212.1 3216076 R 331111 CDS YP_001464213.1 157156288 5588854 complement(3217749..3218456) 1 NC_009801.1 identified by similarity to SP:Q46809; match to protein family HMM TIGR03172; hypothetical protein 3218456 5588854 EcE24377A_3201 Escherichia coli E24377A hypothetical protein YP_001464213.1 3217749 R 331111 CDS YP_001464214.1 157157193 5588965 3218622..3219200 1 NC_009801.1 identified by similarity to SP:Q46810; match to protein family HMM TIGR03310; hypothetical protein 3219200 5588965 EcE24377A_3203 Escherichia coli E24377A hypothetical protein YP_001464214.1 3218622 D 331111 CDS YP_001464215.1 157155724 5586397 complement(3218843..3219073) 1 NC_009801.1 identified by glimmer; hypothetical protein 3219073 5586397 EcE24377A_3202 Escherichia coli E24377A hypothetical protein YP_001464215.1 3218843 R 331111 CDS YP_001464216.1 157156678 5587624 3219522..3222620 1 NC_009801.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; selenate reductase subunit YgfK 3222620 5587624 EcE24377A_3204 Escherichia coli E24377A selenate reductase subunit YgfK YP_001464216.1 3219522 D 331111 CDS YP_001464217.1 157157569 5587388 3222623..3223951 1 NC_009801.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; chlorohydrolase/aminohydrolase 3223951 ssnA 5587388 ssnA Escherichia coli E24377A chlorohydrolase/aminohydrolase YP_001464217.1 3222623 D 331111 CDS YP_001464218.1 157156615 5586200 3224002..3224781 1 NC_009801.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; selenate reductase subunit YgfM 3224781 5586200 EcE24377A_3206 Escherichia coli E24377A selenate reductase subunit YgfM YP_001464218.1 3224002 D 331111 CDS YP_001464219.1 157157789 5590773 3224778..3227648 1 NC_009801.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; selenate reductase subunit YgfN 3227648 5590773 EcE24377A_3207 Escherichia coli E24377A selenate reductase subunit YgfN YP_001464219.1 3224778 D 331111 CDS YP_001464220.1 157157148 5589302 3227813..3229213 1 NC_009801.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine/uracil permease 3229213 5589302 EcE24377A_3208 Escherichia coli E24377A xanthine/uracil permease YP_001464220.1 3227813 D 331111 CDS YP_001464221.1 157155291 5590714 3229231..3230547 1 NC_009801.1 Catalyzes the deamination of guanine; guanine deaminase 3230547 guaD 5590714 guaD Escherichia coli E24377A guanine deaminase YP_001464221.1 3229231 D 331111 CDS YP_001464222.1 157159243 5588860 3230583..3231950 1 NC_009801.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; sulfate permease inorganic anion transporter 3231950 5588860 EcE24377A_3210 Escherichia coli E24377A sulfate permease inorganic anion transporter YP_001464222.1 3230583 D 331111 CDS YP_001464223.1 157154983 5590798 complement(3231986..3232474) 1 NC_009801.1 identified by match to protein family HMM PF00037; (4Fe-4S)-binding protein 3232474 5590798 EcE24377A_3211 Escherichia coli E24377A (4Fe-4S)-binding protein YP_001464223.1 3231986 R 331111 CDS YP_001464224.1 157159085 5590376 complement(3232474..3234393) 1 NC_009801.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 3234393 5590376 EcE24377A_3212 Escherichia coli E24377A oxidoreductase Fe-S binding subunit YP_001464224.1 3232474 R 331111 CDS YP_001464225.1 157155924 5588181 3234829..3236277 1 NC_009801.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine permease 3236277 5588181 EcE24377A_3213 Escherichia coli E24377A xanthine permease YP_001464225.1 3234829 D 331111 CDS YP_001464226.1 157155854 5589572 3236261..3236404 1 NC_009801.1 identified by glimmer; hypothetical protein 3236404 5589572 EcE24377A_3214 Escherichia coli E24377A hypothetical protein YP_001464226.1 3236261 D 331111 CDS YP_001464227.1 157157781 5587222 3236527..3237075 1 NC_009801.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3237075 idi 5587222 idi Escherichia coli E24377A isopentenyl-diphosphate delta-isomerase YP_001464227.1 3236527 D 331111 CDS YP_001464228.1 157155962 5588512 complement(3237118..3238635) 1 NC_009801.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 3238635 lysS 5588512 lysS Escherichia coli E24377A lysyl-tRNA synthetase YP_001464228.1 3237118 R 331111 CDS YP_001464229.1 157155215 5588399 complement(3239834..3241567) 1 NC_009801.1 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 3241567 recJ 5588399 recJ Escherichia coli E24377A ssDNA exonuclease RecJ YP_001464229.1 3239834 R 331111 CDS YP_001464230.1 157155887 5586840 complement(3241573..3242283) 1 NC_009801.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC 3242283 dsbC 5586840 dsbC Escherichia coli E24377A thiol:disulfide interchange protein DsbC YP_001464230.1 3241573 R 331111 CDS YP_001464231.1 157158312 5588602 complement(3242308..3243204) 1 NC_009801.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 3243204 xerD 5588602 xerD Escherichia coli E24377A site-specific tyrosine recombinase XerD YP_001464231.1 3242308 R 331111 CDS YP_001464232.1 157158936 5590170 3243316..3243837 1 NC_009801.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3243837 fldB 5590170 fldB Escherichia coli E24377A flavodoxin FldB YP_001464232.1 3243316 D 331111 CDS YP_001464233.1 157157244 5586217 complement(3243877..3244284) 1 NC_009801.1 identified by match to protein family HMM PF07254; hypothetical protein 3244284 5586217 EcE24377A_3222 Escherichia coli E24377A hypothetical protein YP_001464233.1 3243877 R 331111 CDS YP_001464234.1 157157949 5588593 complement(3244265..3244531) 1 NC_009801.1 identified by match to protein family HMM PF03937; hypothetical protein 3244531 5588593 EcE24377A_3223 Escherichia coli E24377A hypothetical protein YP_001464234.1 3244265 R 331111 CDS YP_001464235.1 157157043 5590191 3244506..3244697 1 NC_009801.1 identified by similarity to GB:AAN81926.1; hypothetical protein 3244697 5590191 EcE24377A_3224 Escherichia coli E24377A hypothetical protein YP_001464235.1 3244506 D 331111 CDS YP_001464236.1 157156395 5588800 3244774..3245754 1 NC_009801.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 3245754 ygfZ 5588800 ygfZ Escherichia coli E24377A global regulator YP_001464236.1 3244774 D 331111 CDS YP_001464237.1 157157229 5589494 complement(3245831..3246490) 1 NC_009801.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065; hemolysin III family channel protein 3246490 5589494 EcE24377A_3226 Escherichia coli E24377A hemolysin III family channel protein YP_001464237.1 3245831 R 331111 CDS YP_001464238.1 157158922 5590140 complement(3246654..3246965) 1 NC_009801.1 identified by match to protein family HMM PF06164; hypothetical protein 3246965 5590140 EcE24377A_3227 Escherichia coli E24377A hypothetical protein YP_001464238.1 3246654 R 331111 CDS YP_001464239.1 157155838 5588940 3247004..3248443 1 NC_009801.1 identified by similarity to SP:Q46829; match to protein family HMM PF00232; 6-phospho-beta-glucosidase 3248443 bglA 5588940 bglA Escherichia coli E24377A 6-phospho-beta-glucosidase YP_001464239.1 3247004 D 331111 CDS YP_001464240.1 157155156 5586860 complement(3248500..3249243) 1 NC_009801.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659; hypothetical protein 3249243 5586860 EcE24377A_3229 Escherichia coli E24377A hypothetical protein YP_001464240.1 3248500 R 331111 CDS YP_001464241.1 157155128 5590750 complement(3249509..3252382) 1 NC_009801.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 3252382 gcvP 5590750 gcvP Escherichia coli E24377A glycine dehydrogenase YP_001464241.1 3249509 R 331111 CDS YP_001464242.1 157157015 5586886 complement(3252501..3252890) 1 NC_009801.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 3252890 gcvH 5586886 gcvH Escherichia coli E24377A glycine cleavage system protein H YP_001464242.1 3252501 R 331111 CDS YP_001464243.1 157156090 5586188 complement(3252914..3254008) 1 NC_009801.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 3254008 gcvT 5586188 gcvT Escherichia coli E24377A glycine cleavage system aminomethyltransferase T YP_001464243.1 3252914 R 331111 CDS YP_001464244.1 157157924 5590559 3254268..3254381 1 NC_009801.1 identified by glimmer; hypothetical protein 3254381 5590559 EcE24377A_3233 Escherichia coli E24377A hypothetical protein YP_001464244.1 3254268 D 331111 CDS YP_001464245.1 157157165 5586987 complement(3254455..3255657) 1 NC_009801.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988; hypothetical protein 3255657 5586987 EcE24377A_3234 Escherichia coli E24377A hypothetical protein YP_001464245.1 3254455 R 331111 CDS YP_001464246.1 157157794 5587500 complement(3255680..3256858) 1 NC_009801.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 3256858 ubiH 5587500 ubiH Escherichia coli E24377A 2-octaprenyl-6-methoxyphenyl hydroxylase YP_001464246.1 3255680 R 331111 CDS YP_001464247.1 157158140 5587672 complement(3256855..3258180) 1 NC_009801.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II 3258180 pepP 5587672 pepP Escherichia coli E24377A proline aminopeptidase P II YP_001464247.1 3256855 R 331111 CDS YP_001464248.1 157156468 5590126 complement(3258206..3258784) 1 NC_009801.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 3258784 5590126 EcE24377A_3237 Escherichia coli E24377A hypothetical protein YP_001464248.1 3258206 R 331111 CDS YP_001464249.1 157156851 5586133 3258952..3259281 1 NC_009801.1 identified by match to protein family HMM PF05164; Z-ring-associated protein 3259281 5586133 EcE24377A_3238 Escherichia coli E24377A Z-ring-associated protein YP_001464249.1 3258952 D 331111 CDS YP_001464250.2 229220664 5586344 3259581..3260129 1 NC_009801.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; ligase 3260129 5586344 EcE24377A_3239 Escherichia coli E24377A ligase YP_001464250.2 3259581 D 331111 CDS YP_001464251.1 157156494 5589463 complement(3260910..3262142) 1 NC_009801.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 3262142 serA 5589463 serA Escherichia coli E24377A D-3-phosphoglycerate dehydrogenase YP_001464251.1 3260910 R 331111 CDS YP_001464252.1 157154730 5590568 complement(3262398..3263057) 1 NC_009801.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 3263057 rpiA 5590568 rpiA Escherichia coli E24377A ribose-5-phosphate isomerase A YP_001464252.1 3262398 R 331111 CDS YP_001464253.1 157155832 5589205 3263440..3264333 1 NC_009801.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3264333 iciA 5589205 iciA Escherichia coli E24377A chromosome replication initiation inhibitor protein YP_001464253.1 3263440 D 331111 CDS YP_001464254.1 157159218 5587345 3264537..3266681 1 NC_009801.1 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 3266681 msm 5587345 msm Escherichia coli E24377A methylmalonyl-CoA mutase YP_001464254.1 3264537 D 331111 CDS YP_001464255.1 157157670 5586664 3266674..3267669 1 NC_009801.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 3267669 5586664 EcE24377A_3245 Escherichia coli E24377A arginine/ornithine transport system ATPase YP_001464255.1 3266674 D 331111 CDS YP_001464256.1 157158191 5589211 3267680..3268465 1 NC_009801.1 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA; methylmalonyl-CoA decarboxylase 3268465 5589211 EcE24377A_3246 Escherichia coli E24377A methylmalonyl-CoA decarboxylase YP_001464256.1 3267680 D 331111 CDS YP_001464257.1 157154952 5590666 complement(3269965..3270861) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 3270861 5590666 EcE24377A_3247 Escherichia coli E24377A LysR family transcriptional regulator YP_001464257.1 3269965 R 331111 CDS YP_001464258.1 157156592 5587424 complement(3271028..3271768) 1 NC_009801.1 identified by similarity to SP:P0ADS8; match to protein family HMM PF04402; hypothetical protein 3271768 5587424 EcE24377A_3249 Escherichia coli E24377A hypothetical protein YP_001464258.1 3271028 R 331111 CDS YP_001464259.1 157154982 5589102 complement(3271861..3272496) 1 NC_009801.1 Involved in the export of arginine; arginine exporter protein 3272496 argO 5589102 argO Escherichia coli E24377A arginine exporter protein YP_001464259.1 3271861 R 331111 CDS YP_001464260.1 157155517 5590375 complement(3272635..3273495) 1 NC_009801.1 participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS 3273495 mscS 5590375 mscS Escherichia coli E24377A mechanosensitive channel MscS YP_001464260.1 3272635 R 331111 CDS YP_001464261.1 157159285 5586018 3273675..3273851 1 NC_009801.1 identified by glimmer; hypothetical protein 3273851 5586018 EcE24377A_3252 Escherichia coli E24377A hypothetical protein YP_001464261.1 3273675 D 331111 CDS YP_001464262.1 157156893 5588170 complement(3273853..3274932) 1 NC_009801.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 3274932 fbaA 5588170 fbaA Escherichia coli E24377A fructose-bisphosphate aldolase YP_001464262.1 3273853 R 331111 CDS YP_001464263.1 157157878 5585986 complement(3275147..3276310) 1 NC_009801.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 3276310 pgk 5585986 pgk Escherichia coli E24377A phosphoglycerate kinase YP_001464263.1 3275147 R 331111 CDS YP_001464264.1 157158683 5588405 complement(3276360..3277379) 1 NC_009801.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 3277379 epd 5588405 epd Escherichia coli E24377A erythrose 4-phosphate dehydrogenase YP_001464264.1 3276360 R 331111 CDS YP_001464265.1 157158888 5586722 complement(3277333..3277434) 1 NC_009801.1 identified by glimmer; hypothetical protein 3277434 5586722 EcE24377A_3256 Escherichia coli E24377A hypothetical protein YP_001464265.1 3277333 R 331111 CDS YP_001464266.1 157154981 5586847 complement(3277580..3277672) 1 NC_009801.1 identified by glimmer; hypothetical protein 3277672 5586847 EcE24377A_3257 Escherichia coli E24377A hypothetical protein YP_001464266.1 3277580 R 331111 CDS YP_001464267.1 157157292 5590557 3277751..3278182 1 NC_009801.1 identified by match to protein family HMM PF03479; hypothetical protein 3278182 5590557 EcE24377A_3258 Escherichia coli E24377A hypothetical protein YP_001464267.1 3277751 D 331111 CDS YP_001464268.1 157157919 5589980 3278205..3278783 1 NC_009801.1 hypothetical protein 3278783 5589980 EcE24377A_3259 Escherichia coli E24377A hypothetical protein YP_001464268.1 3278205 D 331111 CDS YP_001464269.1 157158273 5588496 3278784..3279491 1 NC_009801.1 hypothetical protein 3279491 5588496 EcE24377A_3260 Escherichia coli E24377A hypothetical protein YP_001464269.1 3278784 D 331111 CDS YP_001464270.1 157158885 5586779 3279479..3280156 1 NC_009801.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3280156 5586779 EcE24377A_3261 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001464270.1 3279479 D 331111 CDS YP_001464271.1 157157187 5590449 3280117..3280827 1 NC_009801.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3280827 5590449 EcE24377A_3263 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001464271.1 3280117 D 331111 CDS YP_001464272.1 157155120 5587406 complement(3280799..3281512) 1 NC_009801.1 identified by similarity to GB:AAZ89673.1; fructose transport system kinase 3281512 frcK 5587406 frcK Escherichia coli E24377A fructose transport system kinase YP_001464272.1 3280799 R 331111 CDS YP_001464273.1 157157393 5587194 complement(3281509..3282018) 1 NC_009801.1 identified by match to protein family HMM PF05068; DNA-binding transcriptional regulator 3282018 5587194 EcE24377A_3264 Escherichia coli E24377A DNA-binding transcriptional regulator YP_001464273.1 3281509 R 331111 CDS YP_001464274.1 157158644 5589417 complement(3282040..3283005) 1 NC_009801.1 identified by match to protein family HMM PF03320; match to protein family HMM TIGR00330; fructose-1,6-bisphosphatase II-like protein 3283005 glpX1 5589417 glpX1 Escherichia coli E24377A fructose-1,6-bisphosphatase II-like protein YP_001464274.1 3282040 R 331111 CDS YP_001464275.1 157158379 5589213 complement(3283002..3284279) 1 NC_009801.1 identified by similarity to SP:P37084; match to protein family HMM PF00107; match to protein family HMM PF08240; L-sorbose 1-phosphate reductase 3284279 sorE 5589213 sorE Escherichia coli E24377A L-sorbose 1-phosphate reductase YP_001464275.1 3283002 R 331111 CDS YP_001464276.1 157155472 5587610 complement(3284294..3285682) 1 NC_009801.1 identified by similarity to SP:P69826; match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851; PTS system mannitol-specific transporter subunit cryptic EIICB 3285682 cmtA 5587610 cmtA Escherichia coli E24377A PTS system mannitol-specific transporter subunit cryptic EIICB YP_001464276.1 3284294 R 331111 CDS YP_001464277.1 157156135 5588614 complement(3285710..3286153) 1 NC_009801.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA 3286153 cmtB 5588614 cmtB Escherichia coli E24377A mannitol phosphotransferase subunit EIIA YP_001464277.1 3285710 R 331111 CDS YP_001464278.1 157155441 5587764 complement(3286467..3288458) 1 NC_009801.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 3288458 tkt 5587764 tkt Escherichia coli E24377A transketolase YP_001464278.1 3286467 R 331111 CDS YP_001464279.1 157159240 5588248 3288736..3289494 1 NC_009801.1 identified by match to protein family HMM PF01435; M48B family peptidase 3289494 5588248 EcE24377A_3270 Escherichia coli E24377A M48B family peptidase YP_001464279.1 3288736 D 331111 CDS YP_001464280.1 157159119 5589724 complement(3289550..3290293) 1 NC_009801.1 identified by similarity to GB:AAV79415.1; match to protein family HMM PF07071; hypothetical protein 3290293 5589724 EcE24377A_3271 Escherichia coli E24377A hypothetical protein YP_001464280.1 3289550 R 331111 CDS YP_001464281.1 157158215 5588500 complement(3290280..3291389) 1 NC_009801.1 identified by match to protein family HMM PF01212; match to protein family HMM PF03841; match to protein family HMM TIGR01437; pyridoxal phosphate-dependent enzyme 3291389 5588500 EcE24377A_3272 Escherichia coli E24377A pyridoxal phosphate-dependent enzyme YP_001464281.1 3290280 R 331111 CDS YP_001464282.1 157156199 5587834 3291079..3291189 1 NC_009801.1 identified by glimmer; hypothetical protein 3291189 5587834 EcE24377A_3273 Escherichia coli E24377A hypothetical protein YP_001464282.1 3291079 D 331111 CDS YP_001464283.1 157156196 5586481 complement(3291393..3292250) 1 NC_009801.1 identified by match to protein family HMM PF03613; PTS system mannose/fructose/sorbose family transporter subunit IID 3292250 5586481 EcE24377A_3274 Escherichia coli E24377A PTS system mannose/fructose/sorbose family transporter subunit IID YP_001464283.1 3291393 R 331111 CDS YP_001464284.1 157156564 5588557 complement(3292250..3292999) 1 NC_009801.1 identified by match to protein family HMM PF03609; PTS system sorbose-specific IIC component 3292999 5588557 EcE24377A_3275 Escherichia coli E24377A PTS system sorbose-specific IIC component YP_001464284.1 3292250 R 331111 CDS YP_001464285.1 157154818 5590196 complement(3293025..3293510) 1 NC_009801.1 identified by match to protein family HMM PF03830; PTS system sorbose subfamily transporter subunit IIB 3293510 5590196 EcE24377A_3276 Escherichia coli E24377A PTS system sorbose subfamily transporter subunit IIB YP_001464285.1 3293025 R 331111 CDS YP_001464286.1 157158745 5587173 complement(3293521..3293949) 1 NC_009801.1 identified by match to protein family HMM PF03610; PTS system fructose IIA component 3293949 5587173 EcE24377A_3277 Escherichia coli E24377A PTS system fructose IIA component YP_001464286.1 3293521 R 331111 CDS YP_001464287.1 157158736 5589483 complement(3294068..3296866) 1 NC_009801.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00874; sigma-54 dependent transcription regulator 3296866 5589483 EcE24377A_3278 Escherichia coli E24377A sigma-54 dependent transcription regulator YP_001464287.1 3294068 R 331111 CDS YP_001464288.1 157159456 5589638 complement(3297125..3298045) 1 NC_009801.1 catalyzes the formation of putrescine from agmatine; agmatinase 3298045 speB 5589638 speB Escherichia coli E24377A agmatinase YP_001464288.1 3297125 R 331111 CDS YP_001464289.1 157158095 5587154 complement(3298181..3298912) 1 NC_009801.1 lipoprotein 3298912 5587154 EcE24377A_3280 Escherichia coli E24377A lipoprotein YP_001464289.1 3298181 R 331111 CDS YP_001464290.1 157155489 5590224 complement(3299058..3301034) 1 NC_009801.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 3301034 speA 5590224 speA Escherichia coli E24377A arginine decarboxylase YP_001464290.1 3299058 R 331111 CDS YP_001464291.1 157155729 5587999 complement(3301043..3301189) 1 NC_009801.1 identified by similarity to SP:P64567; hypothetical protein 3301189 5587999 EcE24377A_3282 Escherichia coli E24377A hypothetical protein YP_001464291.1 3301043 R 331111 CDS YP_001464292.1 157155590 5590192 3301509..3301634 1 NC_009801.1 identified by glimmer; hypothetical protein 3301634 5590192 EcE24377A_3283 Escherichia coli E24377A hypothetical protein YP_001464292.1 3301509 D 331111 CDS YP_001464293.1 157158353 5590816 3301829..3302983 1 NC_009801.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3302983 metK 5590816 metK Escherichia coli E24377A S-adenosylmethionine synthetase YP_001464293.1 3301829 D 331111 CDS YP_001464294.1 157158759 5587365 3303046..3303180 1 NC_009801.1 identified by glimmer; hypothetical protein 3303180 5587365 EcE24377A_3285 Escherichia coli E24377A hypothetical protein YP_001464294.1 3303046 D 331111 CDS YP_001464295.1 157159425 5590860 3303419..3304813 1 NC_009801.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879; galactose-proton symporter 3304813 galP 5590860 galP Escherichia coli E24377A galactose-proton symporter YP_001464295.1 3303419 D 331111 CDS YP_001464296.1 157158269 5586960 3304890..3305387 1 NC_009801.1 identified by match to protein family HMM PF03926; hypothetical protein 3305387 5586960 EcE24377A_3287 Escherichia coli E24377A hypothetical protein YP_001464296.1 3304890 D 331111 CDS YP_001464297.1 157156327 5586818 3305482..3306189 1 NC_009801.1 identified by similarity to SP:P25736; match to protein family HMM PF04231; endonuclease I 3306189 endA 5586818 endA Escherichia coli E24377A endonuclease I YP_001464297.1 3305482 D 331111 CDS YP_001464298.1 157156709 5589964 3306269..3307000 1 NC_009801.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3307000 5589964 EcE24377A_3289 Escherichia coli E24377A 16S ribosomal RNA methyltransferase RsmE YP_001464298.1 3306269 D 331111 CDS YP_001464299.1 157154957 5588126 3307013..3307963 1 NC_009801.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3307963 gshB 5588126 gshB Escherichia coli E24377A glutathione synthetase YP_001464299.1 3307013 D 331111 CDS YP_001464300.1 157159272 5587141 3308072..3308635 1 NC_009801.1 identified by similarity to SP:P0A8W7; match to protein family HMM PF02622; hypothetical protein 3308635 5587141 EcE24377A_3291 Escherichia coli E24377A hypothetical protein YP_001464300.1 3308072 D 331111 CDS YP_001464301.1 157158748 5589594 3308635..3309051 1 NC_009801.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3309051 5589594 EcE24377A_3292 Escherichia coli E24377A Holliday junction resolvase-like protein YP_001464301.1 3308635 D 331111 CDS YP_001464302.1 157154978 5589521 3309105..3309209 1 NC_009801.1 identified by glimmer; hypothetical protein 3309209 5589521 EcE24377A_3293 Escherichia coli E24377A hypothetical protein YP_001464302.1 3309105 D 331111 CDS YP_001464303.1 157155068 5588527 complement(3309244..3310224) 1 NC_009801.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420; twitching motility family protein 3310224 5588527 EcE24377A_3294 Escherichia coli E24377A twitching motility family protein YP_001464303.1 3309244 R 331111 CDS YP_001464304.1 157155954 5587081 3310242..3310946 1 NC_009801.1 identified by match to protein family HMM PF01168; match to protein family HMM TIGR00044; alanine racemase 3310946 5587081 EcE24377A_3295 Escherichia coli E24377A alanine racemase YP_001464304.1 3310242 D 331111 CDS YP_001464305.1 157156663 5589323 3310964..3311530 1 NC_009801.1 identified by match to protein family HMM PF02325; hypothetical protein 3311530 5589323 EcE24377A_3296 Escherichia coli E24377A hypothetical protein YP_001464305.1 3310964 D 331111 CDS YP_001464306.1 157155173 5590688 3311515..3311817 1 NC_009801.1 identified by similarity to GB:AAP18250.1; match to protein family HMM PF02594; match to protein family HMM TIGR00251; hypothetical protein 3311817 5590688 EcE24377A_3297 Escherichia coli E24377A hypothetical protein YP_001464306.1 3311515 D 331111 CDS YP_001464307.1 157155704 5590044 3311825..3312418 1 NC_009801.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3312418 rdgB 5590044 rdgB Escherichia coli E24377A deoxyribonucleotide triphosphate pyrophosphatase YP_001464307.1 3311825 D 331111 CDS YP_001464308.1 157155940 5590244 3312411..3313547 1 NC_009801.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3313547 5590244 EcE24377A_3299 Escherichia coli E24377A coproporphyrinogen III oxidase YP_001464308.1 3312411 D 331111 CDS YP_001464309.1 157157011 5588707 complement(3313702..3314709) 1 NC_009801.1 identified by match to protein family HMM PF06717; hypothetical protein 3314709 5588707 EcE24377A_3300 Escherichia coli E24377A hypothetical protein YP_001464309.1 3313702 R 331111 CDS YP_001464310.1 157157301 5589022 complement(3314826..3315872) 1 NC_009801.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 3315872 ansB 5589022 ansB Escherichia coli E24377A L-asparaginase II YP_001464310.1 3314826 R 331111 CDS YP_001464311.1 157156527 5590300 complement(3316048..3316764) 1 NC_009801.1 identified by similarity to SP:P0ADS9; hypothetical protein 3316764 5590300 EcE24377A_3302 Escherichia coli E24377A hypothetical protein YP_001464311.1 3316048 R 331111 CDS YP_001464312.1 157156953 5587251 complement(3316788..3316928) 1 NC_009801.1 identified by glimmer; hypothetical protein 3316928 5587251 EcE24377A_3303 Escherichia coli E24377A hypothetical protein YP_001464312.1 3316788 R 331111 CDS YP_001464313.1 157156150 5590246 complement(3316951..3317277) 1 NC_009801.1 identified by match to protein family HMM PF04320; hypothetical protein 3317277 5590246 EcE24377A_3304 Escherichia coli E24377A hypothetical protein YP_001464313.1 3316951 R 331111 CDS YP_001464314.1 157158006 5587753 complement(3317277..3317996) 1 NC_009801.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 3317996 trmB 5587753 trmB Escherichia coli E24377A tRNA (guanine-N(7)-)-methyltransferase YP_001464314.1 3317277 R 331111 CDS YP_001464315.1 157156921 5590348 3318127..3319209 1 NC_009801.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084; adenine DNA glycosylase 3319209 mutY 5590348 mutY Escherichia coli E24377A adenine DNA glycosylase YP_001464315.1 3318127 D 331111 CDS YP_001464316.1 157157535 5590268 complement(3319186..3319479) 1 NC_009801.1 identified by similarity to GB:AAN81997.1; hypothetical protein 3319479 5590268 EcE24377A_3306 Escherichia coli E24377A hypothetical protein YP_001464316.1 3319186 R 331111 CDS YP_001464317.1 157156392 5588969 3319237..3319512 1 NC_009801.1 identified by match to protein family HMM PF04362; hypothetical protein 3319512 5588969 EcE24377A_3308 Escherichia coli E24377A hypothetical protein YP_001464317.1 3319237 D 331111 CDS YP_001464318.1 157157877 5586060 3319577..3320656 1 NC_009801.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3320656 mltC 5586060 mltC Escherichia coli E24377A murein transglycosylase C YP_001464318.1 3319577 D 331111 CDS YP_001464319.1 157157375 5589872 3320858..3322114 1 NC_009801.1 identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889; nucleoside permease NupG 3322114 nupG 5589872 nupG Escherichia coli E24377A nucleoside permease NupG YP_001464319.1 3320858 D 331111 CDS YP_001464320.1 157158414 5586127 complement(3322164..3324299) 1 NC_009801.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; ornithine decarboxylase 3324299 speC 5586127 speC Escherichia coli E24377A ornithine decarboxylase YP_001464320.1 3322164 R 331111 CDS YP_001464321.1 157155615 5586103 3324697..3325404 1 NC_009801.1 identified by match to protein family HMM PF04474; hypothetical protein 3325404 5586103 EcE24377A_3312 Escherichia coli E24377A hypothetical protein YP_001464321.1 3324697 D 331111 CDS YP_001464322.1 157157483 5586368 3325783..3327045 1 NC_009801.1 identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase 3327045 5586368 EcE24377A_3314 Escherichia coli E24377A site-specific recombinase, phage integrase YP_001464322.1 3325783 D 331111 CDS YP_001464323.1 157156743 5589891 3327458..3327733 1 NC_009801.1 identified by match to protein family HMM PF03811; IS1, transposase orfA 3327733 5589891 EcE24377A_3315 Escherichia coli E24377A IS1, transposase orfA YP_001464323.1 3327458 D 331111 CDS YP_001464324.1 157158541 5588529 3327652..3328155 1 NC_009801.1 identified by match to protein family HMM PF03400; IS1, transposase orfB 3328155 5588529 EcE24377A_3316 Escherichia coli E24377A IS1, transposase orfB YP_001464324.1 3327652 D 331111 CDS YP_001464325.1 157154790 5587115 complement(3329025..3329618) 1 NC_009801.1 identified by similarity to GB:AAS63192.1; hypothetical protein 3329618 5587115 EcE24377A_3318 Escherichia coli E24377A hypothetical protein YP_001464325.1 3329025 R 331111 CDS YP_001464326.1 157155165 5587689 complement(3329739..3329846) 1 NC_009801.1 identified by glimmer; hypothetical protein 3329846 5587689 EcE24377A_3319 Escherichia coli E24377A hypothetical protein YP_001464326.1 3329739 R 331111 CDS YP_001464327.1 157157048 5588071 3330023..3332878 1 NC_009801.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; SNF2 family helicase 3332878 5588071 EcE24377A_3320 Escherichia coli E24377A SNF2 family helicase YP_001464327.1 3330023 D 331111 CDS YP_001464328.1 157156381 5587875 3332904..3333884 1 NC_009801.1 identified by match to protein family HMM PF00004; ATPase AAA 3333884 5587875 EcE24377A_3321 Escherichia coli E24377A ATPase AAA YP_001464328.1 3332904 D 331111 CDS YP_001464329.1 157155742 5587091 3333894..3336281 1 NC_009801.1 identified by match to protein family HMM PF00082; S8A family peptidase 3336281 5587091 EcE24377A_3322 Escherichia coli E24377A S8A family peptidase YP_001464329.1 3333894 D 331111 CDS YP_001464330.1 157155781 5589709 3336291..3337919 1 NC_009801.1 identified by match to protein family HMM PF01555; DNA methylase 3337919 5589709 EcE24377A_3323 Escherichia coli E24377A DNA methylase YP_001464330.1 3336291 D 331111 CDS YP_001464331.1 157156939 5588190 3338000..3340792 1 NC_009801.1 identified by match to protein family HMM PF04851; type III restriction enzyme, res subunit 3340792 5588190 EcE24377A_3325 Escherichia coli E24377A type III restriction enzyme, res subunit YP_001464331.1 3338000 D 331111 CDS YP_001464332.1 157157676 5588079 complement(3340022..3340447) 1 NC_009801.1 identified by glimmer; hypothetical protein 3340447 5588079 EcE24377A_3324 Escherichia coli E24377A hypothetical protein YP_001464332.1 3340022 R 331111 CDS YP_001464333.1 157157930 5590522 complement(3341749..3343257) 1 NC_009801.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388; group II intron-encoded reverse transcriptase/maturase 3343257 5590522 EcE24377A_3327 Escherichia coli E24377A group II intron-encoded reverse transcriptase/maturase YP_001464333.1 3341749 R 331111 CDS YP_001464334.1 157158988 5588136 complement(3344319..3344621) 1 NC_009801.1 identified by match to protein family HMM PF01527; IS911, transposase orfA 3344621 5588136 EcE24377A_3329 Escherichia coli E24377A IS911, transposase orfA YP_001464334.1 3344319 R 331111 CDS YP_001464335.1 157155806 5586991 complement(3345110..3346396) 1 NC_009801.1 identified by similarity to GB:ABA74402.1; hypothetical protein 3346396 5586991 EcE24377A_3330 Escherichia coli E24377A hypothetical protein YP_001464335.1 3345110 R 331111 CDS YP_001464336.1 157155277 5588684 complement(3346389..3348446) 1 NC_009801.1 identified by match to protein family HMM PF07728; ATPase 3348446 5588684 EcE24377A_3331 Escherichia coli E24377A ATPase YP_001464336.1 3346389 R 331111 CDS YP_001464337.1 157159116 5587593 complement(3349219..3349644) 1 NC_009801.1 identified by glimmer; hypothetical protein 3349644 5587593 EcE24377A_3332 Escherichia coli E24377A hypothetical protein YP_001464337.1 3349219 R 331111 CDS YP_001464338.1 157158656 5587421 complement(3349641..3350024) 1 NC_009801.1 identified by similarity to GB:AAK00467.1; hypothetical protein 3350024 5587421 EcE24377A_3333 Escherichia coli E24377A hypothetical protein YP_001464338.1 3349641 R 331111 CDS YP_001464339.1 157157098 5586450 complement(3351226..3351366) 1 NC_009801.1 identified by match to protein family HMM PF05321; hemolysin expression modulating protein 3351366 5586450 EcE24377A_3334 Escherichia coli E24377A hemolysin expression modulating protein YP_001464339.1 3351226 R 331111 CDS YP_001464340.1 157157552 5587553 3352444..3353235 1 NC_009801.1 identified by similarity to GB:AAN44467.1; hypothetical protein 3353235 5587553 EcE24377A_3335 Escherichia coli E24377A hypothetical protein YP_001464340.1 3352444 D 331111 CDS YP_001464341.1 157156534 5586439 3353914..3354522 1 NC_009801.1 identified by similarity to GB:AAL08467.1; hypothetical protein 3354522 5586439 EcE24377A_3337 Escherichia coli E24377A hypothetical protein YP_001464341.1 3353914 D 331111 CDS YP_001464342.1 157157419 5586974 3356792..3357814 1 NC_009801.1 identified by similarity to GB:AAZ76440.1; match to protein family HMM PF00665; match to protein family HMM PF02796; IS100, transposase 3357814 5586974 EcE24377A_3338 Escherichia coli E24377A IS100, transposase YP_001464342.1 3356792 D 331111 CDS YP_001464343.1 157158077 5589513 complement(3358162..3358956) 1 NC_009801.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695; IS21 family transposition helper protein 3358956 5589513 EcE24377A_3339 Escherichia coli E24377A IS21 family transposition helper protein YP_001464343.1 3358162 R 331111 CDS YP_001464344.1 157156788 5590577 complement(3358956..3360128) 1 NC_009801.1 identified by similarity to SP:P15025; match to protein family HMM PF00665; IS21 family transposase 3360128 5590577 EcE24377A_3341 Escherichia coli E24377A IS21 family transposase YP_001464344.1 3358956 R 331111 CDS YP_001464345.1 157154872 5589035 complement(3361455..3362993) 1 NC_009801.1 identified by match to protein family HMM PF03050; IS66 family transposase 3362993 5589035 EcE24377A_3343 Escherichia coli E24377A IS66 family transposase YP_001464345.1 3361455 R 331111 CDS YP_001464346.1 157158853 5587590 complement(3363043..3363390) 1 NC_009801.1 identified by match to protein family HMM PF05717; IS66 family orf2 3363390 5587590 EcE24377A_3344 Escherichia coli E24377A IS66 family orf2 YP_001464346.1 3363043 R 331111 CDS YP_001464347.1 157157027 5589882 complement(3363387..3363776) 1 NC_009801.1 identified by match to protein family HMM PF01527; IS66 family orf1 3363776 5589882 EcE24377A_3345 Escherichia coli E24377A IS66 family orf1 YP_001464347.1 3363387 R 331111 CDS YP_001464348.1 157156541 5589149 3364192..3365064 1 NC_009801.1 identified by match to protein family HMM PF01926; GTPase 3365064 5589149 EcE24377A_3346 Escherichia coli E24377A GTPase YP_001464348.1 3364192 D 331111 CDS YP_001464349.1 157154748 5589947 3365436..3368282 1 NC_009801.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; antigen 43 3368282 flu2 5589947 flu2 Escherichia coli E24377A antigen 43 YP_001464349.1 3365436 D 331111 CDS YP_001464350.1 157155585 5587063 3368610..3369428 1 NC_009801.1 identified by match to protein family HMM PF06067; hypothetical protein 3369428 5587063 EcE24377A_3348 Escherichia coli E24377A hypothetical protein YP_001464350.1 3368610 D 331111 CDS YP_001464351.1 157156040 5590363 3369520..3370002 1 NC_009801.1 identified by match to protein family HMM PF03230; antirestriction protein 3370002 5590363 EcE24377A_3349 Escherichia coli E24377A antirestriction protein YP_001464351.1 3369520 D 331111 CDS YP_001464352.1 157156526 5588333 3370018..3370494 1 NC_009801.1 identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608; RadC family DNA repair protein 3370494 5588333 EcE24377A_3350 Escherichia coli E24377A RadC family DNA repair protein YP_001464352.1 3370018 D 331111 CDS YP_001464353.1 157155094 5587250 3370581..3370802 1 NC_009801.1 identified by similarity to GB:AAP18295.1; match to protein family HMM PF06174; hypothetical protein 3370802 5587250 EcE24377A_3351 Escherichia coli E24377A hypothetical protein YP_001464353.1 3370581 D 331111 CDS YP_001464354.1 157155482 5588772 3370882..3371250 1 NC_009801.1 identified by similarity to GB:BAB36228.1; match to protein family HMM PF06154; hypothetical protein 3371250 5588772 EcE24377A_3352 Escherichia coli E24377A hypothetical protein YP_001464354.1 3370882 D 331111 CDS YP_001464355.1 157158874 5586789 3371340..3371717 1 NC_009801.1 identified by match to protein family HMM PF06755; hypothetical protein 3371717 5586789 EcE24377A_3353 Escherichia coli E24377A hypothetical protein YP_001464355.1 3371340 D 331111 CDS YP_001464356.1 157156296 5586866 3371714..3372136 1 NC_009801.1 identified by similarity to GB:AAN83011.1; match to protein family HMM PF06117; hypothetical protein 3372136 5586866 EcE24377A_3354 Escherichia coli E24377A hypothetical protein YP_001464356.1 3371714 D 331111 CDS YP_001464357.1 157155905 5589241 3372221..3373063 1 NC_009801.1 identified by similarity to GB:CAE85207.1; hypothetical protein 3373063 5589241 EcE24377A_3355 Escherichia coli E24377A hypothetical protein YP_001464357.1 3372221 D 331111 CDS YP_001464358.1 157157376 5586549 complement(3373401..3374459) 1 NC_009801.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; phage integrase 3374459 5586549 EcE24377A_3356 Escherichia coli E24377A phage integrase YP_001464358.1 3373401 R 331111 CDS YP_001464359.1 157156708 5586099 complement(3374501..3376156) 1 NC_009801.1 identified by match to protein family HMM PF07515; helicase/Zfx/Zfy transcription activation region domain-containing protein 3376156 5586099 EcE24377A_3357 Escherichia coli E24377A helicase/Zfx/Zfy transcription activation region domain-containing protein YP_001464359.1 3374501 R 331111 CDS YP_001464360.1 157158381 5589924 complement(3376149..3377678) 1 NC_009801.1 hypothetical protein 3377678 5589924 EcE24377A_3358 Escherichia coli E24377A hypothetical protein YP_001464360.1 3376149 R 331111 CDS YP_001464361.1 157157710 5589916 complement(3377803..3381057) 1 NC_009801.1 identified by match to protein family HMM PF02369; Ig family protein 3381057 5589916 EcE24377A_3359 Escherichia coli E24377A Ig family protein YP_001464361.1 3377803 R 331111 CDS YP_001464362.1 157155882 5590694 3381237..3381629 1 NC_009801.1 identified by glimmer; hypothetical protein 3381629 5590694 EcE24377A_3360 Escherichia coli E24377A hypothetical protein YP_001464362.1 3381237 D 331111 CDS YP_001464363.1 157155200 5587159 complement(3382305..3382964) 1 NC_009801.1 identified by glimmer; hypothetical protein 3382964 5587159 EcE24377A_3361 Escherichia coli E24377A hypothetical protein YP_001464363.1 3382305 R 331111 CDS YP_001464364.1 157156759 5587847 complement(3383223..3385115) 1 NC_009801.1 identified by match to protein family HMM PF00580; UvrD family helicase 3385115 5587847 EcE24377A_3362 Escherichia coli E24377A UvrD family helicase YP_001464364.1 3383223 R 331111 CDS YP_001464365.1 157156101 5590167 complement(3385117..3386940) 1 NC_009801.1 identified by glimmer; hypothetical protein 3386940 5590167 EcE24377A_3363 Escherichia coli E24377A hypothetical protein YP_001464365.1 3385117 R 331111 CDS YP_001464366.1 157155468 5590379 complement(3387412..3388104) 1 NC_009801.1 identified by similarity to GB:CAE13457.1; hypothetical protein 3388104 5590379 EcE24377A_3365 Escherichia coli E24377A hypothetical protein YP_001464366.1 3387412 R 331111 CDS YP_001464367.1 157157992 5590002 3388145..3388822 1 NC_009801.1 identified by match to protein family HMM PF01527; IS66 family orf1 3388822 5590002 EcE24377A_3366 Escherichia coli E24377A IS66 family orf1 YP_001464367.1 3388145 D 331111 CDS YP_001464368.1 157157516 5587649 3388822..3389169 1 NC_009801.1 identified by match to protein family HMM PF05717; IS66 family orf2 3389169 5587649 EcE24377A_3367 Escherichia coli E24377A IS66 family orf2 YP_001464368.1 3388822 D 331111 CDS YP_001464369.1 157159346 5589818 3389189..3390760 1 NC_009801.1 identified by match to protein family HMM PF03050; IS66 family transposase 3390760 5589818 EcE24377A_3368 Escherichia coli E24377A IS66 family transposase YP_001464369.1 3389189 D 331111 CDS YP_001464370.1 157157772 5587865 complement(3390926..3391753) 1 NC_009801.1 identified by similarity to SP:P15026; match to protein family HMM PF01695; IS21 family transposition helper protein 3391753 5587865 EcE24377A_3369 Escherichia coli E24377A IS21 family transposition helper protein YP_001464370.1 3390926 R 331111 CDS YP_001464371.1 157155459 5588534 complement(3391753..3392925) 1 NC_009801.1 identified by match to protein family HMM PF00665; IS21 family transposase 3392925 5588534 EcE24377A_3370 Escherichia coli E24377A IS21 family transposase YP_001464371.1 3391753 R 331111 CDS YP_001464372.1 157156805 5586433 complement(3393100..3394467) 1 NC_009801.1 identified by similarity to SP:P0ACB0; match to protein family HMM PF00772; match to protein family HMM PF03796; match to protein family HMM TIGR00665; DnaB family helicase 3394467 5586433 EcE24377A_3371 Escherichia coli E24377A DnaB family helicase YP_001464372.1 3393100 R 331111 CDS YP_001464373.1 157156134 5587561 3394664..3395029 1 NC_009801.1 identified by glimmer; hypothetical protein 3395029 5587561 EcE24377A_3372 Escherichia coli E24377A hypothetical protein YP_001464373.1 3394664 D 331111 CDS YP_001464374.1 157156365 5587787 complement(3395463..3396173) 1 NC_009801.1 identified by glimmer; hypothetical protein 3396173 5587787 EcE24377A_3373 Escherichia coli E24377A hypothetical protein YP_001464374.1 3395463 R 331111 CDS YP_001464375.1 157157047 5588365 complement(3396170..3396430) 1 NC_009801.1 identified by glimmer; hypothetical protein 3396430 5588365 EcE24377A_3374 Escherichia coli E24377A hypothetical protein YP_001464375.1 3396170 R 331111 CDS YP_001464376.1 157155181 5587874 complement(3396424..3397308) 1 NC_009801.1 chromosome partitioning protein 3397308 5587874 EcE24377A_3375 Escherichia coli E24377A chromosome partitioning protein YP_001464376.1 3396424 R 331111 CDS YP_001464377.1 157158376 5586022 3397619..3398803 1 NC_009801.1 identified by match to protein family HMM PF00589; site-specific recombinase, phage integrase 3398803 5586022 EcE24377A_3377 Escherichia coli E24377A site-specific recombinase, phage integrase YP_001464377.1 3397619 D 331111 CDS YP_001464378.1 157157616 5590621 3398953..3399963 1 NC_009801.1 identified by similarity to SP:P21867; match to protein family HMM PF00356; match to protein family HMM PF00532; HTH-type transcriptional regulator RafR 3399963 rafR 5590621 rafR Escherichia coli E24377A HTH-type transcriptional regulator RafR YP_001464378.1 3398953 D 331111 CDS YP_001464379.1 157158278 5589615 3400059..3402185 1 NC_009801.1 identified by similarity to SP:P16551; match to protein family HMM PF02065; alpha-galactosidase 3402185 rafA 5589615 rafA Escherichia coli E24377A alpha-galactosidase YP_001464379.1 3400059 D 331111 CDS YP_001464380.1 157156266 5588203 3402233..3403525 1 NC_009801.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 3403525 lacY 5588203 lacY Escherichia coli E24377A galactoside permease YP_001464380.1 3402233 D 331111 CDS YP_001464381.1 157155023 5588444 3403525..3404955 1 NC_009801.1 identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322; raffinose invertase 3404955 rafD 5588444 rafD Escherichia coli E24377A raffinose invertase YP_001464381.1 3403525 D 331111 CDS YP_001464382.1 157156638 5589945 3405150..3406544 1 NC_009801.1 identified by similarity to GB:AAB71432.1; glycoporin RafY 3406544 rafY 5589945 rafY Escherichia coli E24377A glycoporin RafY YP_001464382.1 3405150 D 331111 CDS YP_001464383.1 157155964 5587246 complement(3406621..3408159) 1 NC_009801.1 identified by match to protein family HMM PF03050; IS66 family transposase 3408159 5587246 EcE24377A_3384 Escherichia coli E24377A IS66 family transposase YP_001464383.1 3406621 R 331111 CDS YP_001464384.1 157155899 5586226 complement(3408209..3408556) 1 NC_009801.1 identified by match to protein family HMM PF05717; IS66 family orf2 3408556 5586226 EcE24377A_3385 Escherichia coli E24377A IS66 family orf2 YP_001464384.1 3408209 R 331111 CDS YP_001464385.1 157159321 5590393 complement(3408553..3408942) 1 NC_009801.1 identified by match to protein family HMM PF01527; IS66 family orf1 3408942 5590393 EcE24377A_3386 Escherichia coli E24377A IS66 family orf1 YP_001464385.1 3408553 R 331111 CDS YP_001464386.1 157158739 5589313 complement(3409199..3409633) 1 NC_009801.1 identified by similarity to SP:P0ACF8; match to protein family HMM PF00816; DNA-binding protein H-NS-like protein 3409633 5589313 EcE24377A_3387 Escherichia coli E24377A DNA-binding protein H-NS-like protein YP_001464386.1 3409199 R 331111 CDS YP_001464387.1 157156712 5589441 complement(3410890..3411438) 1 NC_009801.1 identified by glimmer; hypothetical protein 3411438 5589441 EcE24377A_3389 Escherichia coli E24377A hypothetical protein YP_001464387.1 3410890 R 331111 CDS YP_001464388.1 157159282 5585954 complement(3413148..3413378) 1 NC_009801.1 identified by match to protein family HMM PF05930; prophage CP4-57 regulatory protein 3413378 5585954 EcE24377A_3391 Escherichia coli E24377A prophage CP4-57 regulatory protein YP_001464388.1 3413148 R 331111 CDS YP_001464389.1 157154808 5588228 complement(3413447..3414049) 1 NC_009801.1 identified by glimmer; hypothetical protein 3414049 5588228 EcE24377A_3392 Escherichia coli E24377A hypothetical protein YP_001464389.1 3413447 R 331111 CDS YP_001464390.1 157155762 5587203 complement(3414206..3414355) 1 NC_009801.1 identified by glimmer; hypothetical protein 3414355 5587203 EcE24377A_3393 Escherichia coli E24377A hypothetical protein YP_001464390.1 3414206 R 331111 CDS YP_001464391.1 157155977 5589051 complement(3414352..3414462) 1 NC_009801.1 identified by glimmer; hypothetical protein 3414462 5589051 EcE24377A_3394 Escherichia coli E24377A hypothetical protein YP_001464391.1 3414352 R 331111 CDS YP_001464392.1 157156753 5589612 complement(3414380..3415111) 1 NC_009801.1 identified by similarity to GB:CAD42091.1; hypothetical protein 3415111 5589612 EcE24377A_3395 Escherichia coli E24377A hypothetical protein YP_001464392.1 3414380 R 331111 CDS YP_001464393.1 157157236 5586120 complement(3415155..3415274) 1 NC_009801.1 identified by glimmer; hypothetical protein 3415274 5586120 EcE24377A_3396 Escherichia coli E24377A hypothetical protein YP_001464393.1 3415155 R 331111 CDS YP_001464394.1 157157481 5587691 3415291..3415464 1 NC_009801.1 identified by glimmer; hypothetical protein 3415464 5587691 EcE24377A_3397 Escherichia coli E24377A hypothetical protein YP_001464394.1 3415291 D 331111 CDS YP_001464395.1 157157991 5587952 3415659..3415754 1 NC_009801.1 identified by glimmer; hypothetical protein 3415754 5587952 EcE24377A_3398 Escherichia coli E24377A hypothetical protein YP_001464395.1 3415659 D 331111 CDS YP_001464396.1 157158339 5587648 complement(3416696..3417826) 1 NC_009801.1 identified by glimmer; hypothetical protein 3417826 5587648 EcE24377A_3399 Escherichia coli E24377A hypothetical protein YP_001464396.1 3416696 R 331111 CDS YP_001464397.1 157157498 5590467 3416900..3417037 1 NC_009801.1 identified by glimmer; hypothetical protein 3417037 5590467 EcE24377A_3400 Escherichia coli E24377A hypothetical protein YP_001464397.1 3416900 D 331111 CDS YP_001464398.1 157158027 5588889 3417298..3417471 1 NC_009801.1 identified by glimmer; hypothetical protein 3417471 5588889 EcE24377A_3401 Escherichia coli E24377A hypothetical protein YP_001464398.1 3417298 D 331111 CDS YP_001464399.1 157156484 5588761 3418011..3418895 1 NC_009801.1 identified by match to protein family HMM PF01926; GTPase 3418895 5588761 EcE24377A_3402 Escherichia coli E24377A GTPase YP_001464399.1 3418011 D 331111 CDS YP_001464400.1 157157033 5590563 3418914..3419069 1 NC_009801.1 identified by glimmer; hypothetical protein 3419069 5590563 EcE24377A_3403 Escherichia coli E24377A hypothetical protein YP_001464400.1 3418914 D 331111 CDS YP_001464401.1 157154959 5586235 3419098..3419778 1 NC_009801.1 identified by match to protein family HMM PF08279; hypothetical protein 3419778 5586235 EcE24377A_3405 Escherichia coli E24377A hypothetical protein YP_001464401.1 3419098 D 331111 CDS YP_001464402.1 157156648 5587904 complement(3419662..3419793) 1 NC_009801.1 identified by glimmer; hypothetical protein 3419793 5587904 EcE24377A_3404 Escherichia coli E24377A hypothetical protein YP_001464402.1 3419662 R 331111 CDS YP_001464403.1 157155461 5589136 3419821..3420603 1 NC_009801.1 identified by glimmer; hypothetical protein 3420603 5589136 EcE24377A_3406 Escherichia coli E24377A hypothetical protein YP_001464403.1 3419821 D 331111 CDS YP_001464404.1 157158658 5586435 3420609..3420842 1 NC_009801.1 identified by match to protein family HMM PF06006; hypothetical protein 3420842 5586435 EcE24377A_3407 Escherichia coli E24377A hypothetical protein YP_001464404.1 3420609 D 331111 CDS YP_001464405.1 157159250 5586452 3420932..3421750 1 NC_009801.1 identified by match to protein family HMM PF06067; hypothetical protein 3421750 5586452 EcE24377A_3408 Escherichia coli E24377A hypothetical protein YP_001464405.1 3420932 D 331111 CDS YP_001464406.1 157155313 5589238 3421842..3422327 1 NC_009801.1 identified by match to protein family HMM PF03230; antirestriction protein 3422327 5589238 EcE24377A_3409 Escherichia coli E24377A antirestriction protein YP_001464406.1 3421842 D 331111 CDS YP_001464407.1 157154969 5586311 3422343..3422819 1 NC_009801.1 identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608; RadC family DNA repair protein 3422819 5586311 EcE24377A_3410 Escherichia coli E24377A RadC family DNA repair protein YP_001464407.1 3422343 D 331111 CDS YP_001464408.1 157158252 5589462 3422906..3423127 1 NC_009801.1 identified by match to protein family HMM PF06174; hypothetical protein 3423127 5589462 EcE24377A_3411 Escherichia coli E24377A hypothetical protein YP_001464408.1 3422906 D 331111 CDS YP_001464409.1 157157504 5590381 3423207..3423575 1 NC_009801.1 identified by similarity to GB:AAP18296.1; match to protein family HMM PF06154; hypothetical protein 3423575 5590381 EcE24377A_3412 Escherichia coli E24377A hypothetical protein YP_001464409.1 3423207 D 331111 CDS YP_001464410.1 157158025 5588996 3423665..3424042 1 NC_009801.1 identified by match to protein family HMM PF06755; hypothetical protein 3424042 5588996 EcE24377A_3413 Escherichia coli E24377A hypothetical protein YP_001464410.1 3423665 D 331111 CDS YP_001464411.1 157157507 5589786 3424039..3424527 1 NC_009801.1 identified by similarity to GB:ABB61173.1; hypothetical protein 3424527 5589786 EcE24377A_3414 Escherichia coli E24377A hypothetical protein YP_001464411.1 3424039 D 331111 CDS YP_001464412.1 157156688 5588149 3424494..3424736 1 NC_009801.1 identified by match to protein family HMM PF06117; hypothetical protein 3424736 5588149 EcE24377A_3415 Escherichia coli E24377A hypothetical protein YP_001464412.1 3424494 D 331111 CDS YP_001464413.1 157156191 5587412 3424821..3425666 1 NC_009801.1 identified by similarity to GB:BAB34832.1; hypothetical protein 3425666 5587412 EcE24377A_3416 Escherichia coli E24377A hypothetical protein YP_001464413.1 3424821 D 331111 CDS YP_001464414.1 157155329 5588913 3426123..3427070 1 NC_009801.1 identified by similarity to GB:CAE16642.1; match to protein family HMM PF08843; hypothetical protein 3427070 5588913 EcE24377A_3417 Escherichia coli E24377A hypothetical protein YP_001464414.1 3426123 D 331111 CDS YP_001464415.1 157154814 5586708 complement(3427425..3427961) 1 NC_009801.1 identified by similarity to SP:P41851; match to protein family HMM PF04612; general secretion pathway protein YghD 3427961 gspM 5586708 gspM Escherichia coli E24377A general secretion pathway protein YghD YP_001464415.1 3427425 R 331111 CDS YP_001464416.1 157156601 5587276 complement(3427963..3429141) 1 NC_009801.1 similar to general secretory pathway protein L; GspL-like protein 3429141 gspL 5587276 gspL Escherichia coli E24377A GspL-like protein YP_001464416.1 3427963 R 331111 CDS YP_001464417.1 157155920 5589996 complement(3429138..3430115) 1 NC_009801.1 identified by match to protein family HMM PF03934; general secretion pathway protein K 3430115 gspK 5589996 gspK Escherichia coli E24377A general secretion pathway protein K YP_001464417.1 3429138 R 331111 CDS YP_001464418.1 157157609 5587390 complement(3430118..3430717) 1 NC_009801.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR01711; match to protein family HMM TIGR02532; general secretion pathway protein J 3430717 gspJ 5587390 gspJ Escherichia coli E24377A general secretion pathway protein J YP_001464418.1 3430118 R 331111 CDS YP_001464419.1 157156956 5588351 complement(3430714..3431085) 1 NC_009801.1 identified by match to protein family HMM PF02501; match to protein family HMM PF07963; match to protein family HMM TIGR01707; match to protein family HMM TIGR02532; general secretion pathway protein I 3431085 gspI 5588351 gspI Escherichia coli E24377A general secretion pathway protein I YP_001464419.1 3430714 R 331111 CDS YP_001464420.1 157158634 5587607 complement(3431082..3431645) 1 NC_009801.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR01708; match to protein family HMM TIGR02532; general secretion pathway protein H 3431645 gspH 5587607 gspH Escherichia coli E24377A general secretion pathway protein H YP_001464420.1 3431082 R 331111 CDS YP_001464421.1 157157959 5587857 complement(3431649..3432104) 1 NC_009801.1 identified by match to protein family HMM PF07963; match to protein family HMM PF08334; match to protein family HMM TIGR01710; match to protein family HMM TIGR02532; general secretion pathway protein G 3432104 gspG 5587857 gspG Escherichia coli E24377A general secretion pathway protein G YP_001464421.1 3431649 R 331111 CDS YP_001464422.1 157154920 5586655 complement(3432121..3433344) 1 NC_009801.1 identified by match to protein family HMM PF00482; match to protein family HMM TIGR02120; general secretion pathway protein F 3433344 gspF 5586655 gspF Escherichia coli E24377A general secretion pathway protein F YP_001464422.1 3432121 R 331111 CDS YP_001464423.1 157159001 5588322 complement(3433344..3434837) 1 NC_009801.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR02533; general secretory pathway protein E 3434837 gspE 5588322 gspE Escherichia coli E24377A general secretory pathway protein E YP_001464423.1 3433344 R 331111 CDS YP_001464424.1 157157281 5588088 complement(3434837..3436897) 1 NC_009801.1 identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02517; general secretion pathway protein D 3436897 gspD 5588088 gspD Escherichia coli E24377A general secretion pathway protein D YP_001464424.1 3434837 R 331111 CDS YP_001464425.1 157156659 5590427 complement(3436927..3437886) 1 NC_009801.1 part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm; type II secretion protein GspC 3437886 gspC 5590427 gspC Escherichia coli E24377A type II secretion protein GspC YP_001464425.1 3436927 R 331111 CDS YP_001464426.1 157154984 5589346 complement(3437904..3438314) 1 NC_009801.1 lipoprotein 3438314 5589346 EcE24377A_3429 Escherichia coli E24377A lipoprotein YP_001464426.1 3437904 R 331111 CDS YP_001464427.1 157155400 5587346 complement(3438380..3439189) 1 NC_009801.1 identified by similarity to SP:P31712; match to protein family HMM PF01478; match to protein family HMM PF06750; type IV prepilin peptidase 3439189 5587346 EcE24377A_3430 Escherichia coli E24377A type IV prepilin peptidase YP_001464427.1 3438380 R 331111 CDS YP_001464428.1 157156378 5587456 3439213..3439314 1 NC_009801.1 identified by glimmer; hypothetical protein 3439314 5587456 EcE24377A_3431 Escherichia coli E24377A hypothetical protein YP_001464428.1 3439213 D 331111 CDS YP_001464429.1 157156747 5590611 complement(3439337..3443857) 1 NC_009801.1 identified by glimmer; hypothetical protein 3443857 5590611 EcE24377A_3432 Escherichia coli E24377A hypothetical protein YP_001464429.1 3439337 R 331111 CDS YP_001464430.1 157158202 5589159 3444053..3444361 1 NC_009801.1 identified by glimmer; hypothetical protein 3444361 5589159 EcE24377A_3433 Escherichia coli E24377A hypothetical protein YP_001464430.1 3444053 D 331111 CDS YP_001464431.1 157156489 5589399 complement(3444389..3446071) 1 NC_009801.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795; glycolate transporter 3446071 glcA 5589399 glcA Escherichia coli E24377A glycolate transporter YP_001464431.1 3444389 R 331111 CDS YP_001464432.1 157157164 5590624 complement(3446427..3448598) 1 NC_009801.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 3448598 glcB 5590624 glcB Escherichia coli E24377A malate synthase G YP_001464432.1 3446427 R 331111 CDS YP_001464433.1 157157823 5587499 complement(3448620..3449024) 1 NC_009801.1 identified by match to protein family HMM PF03928; hypothetical protein 3449024 5587499 EcE24377A_3436 Escherichia coli E24377A hypothetical protein YP_001464433.1 3448620 R 331111 CDS YP_001464434.1 157155598 5589075 complement(3449029..3450252) 1 NC_009801.1 identified by similarity to SP:P52074; match to protein family HMM PF00037; match to protein family HMM PF02754; glycolate oxidase iron-sulfur subunit 3450252 glcF 5589075 glcF Escherichia coli E24377A glycolate oxidase iron-sulfur subunit YP_001464434.1 3449029 R 331111 CDS YP_001464435.1 157158300 5587191 complement(3450263..3451315) 1 NC_009801.1 identified by match to protein family HMM PF01565; glycolate oxidase FAD binding subunit 3451315 glcE 5587191 glcE Escherichia coli E24377A glycolate oxidase FAD binding subunit YP_001464435.1 3450263 R 331111 CDS YP_001464436.1 157159206 5587883 complement(3451315..3452805) 1 NC_009801.1 identified by similarity to SP:P52075; match to protein family HMM PF01565; match to protein family HMM PF02913; match to protein family HMM TIGR00387; glycolate oxidase subunit GlcD 3452805 glcD 5587883 glcD Escherichia coli E24377A glycolate oxidase subunit GlcD YP_001464436.1 3451315 R 331111 CDS YP_001464437.1 157158667 5589190 3453065..3453829 1 NC_009801.1 identified by similarity to SP:P0ACL5; match to protein family HMM PF00392; match to protein family HMM PF07729; DNA-binding transcriptional regulator GlcC 3453829 glcC 5589190 glcC Escherichia coli E24377A DNA-binding transcriptional regulator GlcC YP_001464437.1 3453065 D 331111 CDS YP_001464438.1 157158193 5587288 complement(3453836..3454978) 1 NC_009801.1 identified by glimmer; hypothetical protein 3454978 5587288 EcE24377A_3441 Escherichia coli E24377A hypothetical protein YP_001464438.1 3453836 R 331111 CDS YP_001464439.1 157157683 5590602 3455340..3457070 1 NC_009801.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3457070 5590602 EcE24377A_3442 Escherichia coli E24377A acyl-CoA synthetase YP_001464439.1 3455340 D 331111 CDS YP_001464440.1 157154742 5590493 3457067..3457981 1 NC_009801.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF05368; match to protein family HMM PF07993; NAD dependent epimerase/dehydratase 3457981 5590493 EcE24377A_3443 Escherichia coli E24377A NAD dependent epimerase/dehydratase YP_001464440.1 3457067 D 331111 CDS YP_001464441.1 157156549 5589028 3458013..3458261 1 NC_009801.1 identified by match to protein family HMM PF00550; acyl carrier protein 3458261 5589028 EcE24377A_3444 Escherichia coli E24377A acyl carrier protein YP_001464441.1 3458013 D 331111 CDS YP_001464442.1 157158668 5586319 3458261..3459433 1 NC_009801.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00202; class I/II aminotransferase 3459433 5586319 EcE24377A_3445 Escherichia coli E24377A class I/II aminotransferase YP_001464442.1 3458261 D 331111 CDS YP_001464443.1 157155522 5590830 complement(3459469..3460548) 1 NC_009801.1 identified by match to protein family HMM PF03739; YjgP/YjgQ permease 3460548 5590830 EcE24377A_3446 Escherichia coli E24377A YjgP/YjgQ permease YP_001464443.1 3459469 R 331111 CDS YP_001464444.1 157156628 5586011 complement(3460545..3461615) 1 NC_009801.1 identified by match to protein family HMM PF03739; YjgP/YjgQ permease 3461615 5586011 EcE24377A_3447 Escherichia coli E24377A YjgP/YjgQ permease YP_001464444.1 3460545 R 331111 CDS YP_001464445.1 157158165 5587102 complement(3461646..3462206) 1 NC_009801.1 identified by match to protein family HMM TIGR01626; hypothetical protein 3462206 5587102 EcE24377A_3448 Escherichia coli E24377A hypothetical protein YP_001464445.1 3461646 R 331111 CDS YP_001464446.1 157156961 5589001 complement(3462218..3463042) 1 NC_009801.1 identified by similarity to GB:AAN82163.1; hypothetical protein 3463042 5589001 EcE24377A_3449 Escherichia coli E24377A hypothetical protein YP_001464446.1 3462218 R 331111 CDS YP_001464447.1 157156727 5587385 complement(3463042..3464391) 1 NC_009801.1 identified by match to protein family HMM PF01943; polysaccharide biosynthesis protein 3464391 5587385 EcE24377A_3450 Escherichia coli E24377A polysaccharide biosynthesis protein YP_001464447.1 3463042 R 331111 CDS YP_001464448.1 157157115 5589353 complement(3464437..3465195) 1 NC_009801.1 identified by similarity to GB:AAV89941.1; hypothetical protein 3465195 5589353 EcE24377A_3451 Escherichia coli E24377A hypothetical protein YP_001464448.1 3464437 R 331111 CDS YP_001464449.1 157158293 5590640 complement(3465227..3465940) 1 NC_009801.1 lipoprotein 3465940 5590640 EcE24377A_3452 Escherichia coli E24377A lipoprotein YP_001464449.1 3465227 R 331111 CDS YP_001464450.1 157158978 5586889 3466114..3466806 1 NC_009801.1 hypothetical protein 3466806 5586889 EcE24377A_3453 Escherichia coli E24377A hypothetical protein YP_001464450.1 3466114 D 331111 CDS YP_001464451.1 157155207 5587830 complement(3466855..3468354) 1 NC_009801.1 identified by match to protein family HMM PF01384; low-affinity inorganic phosphate transporter 2 3468354 pitB 5587830 pitB Escherichia coli E24377A low-affinity inorganic phosphate transporter 2 YP_001464451.1 3466855 R 331111 CDS YP_001464452.1 157155848 5587475 complement(3468646..3470505) 1 NC_009801.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 3470505 gsp 5587475 gsp Escherichia coli E24377A bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase YP_001464452.1 3468646 R 331111 CDS YP_001464453.1 157159060 5590289 3470710..3471576 1 NC_009801.1 YghU; B2989; one of eight glutathione transferases from E. coli; glutathione S-transferase 3471576 5590289 EcE24377A_3456 Escherichia coli E24377A glutathione S-transferase YP_001464453.1 3470710 D 331111 CDS YP_001464454.1 157158575 5590618 3471876..3472856 1 NC_009801.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 3472856 5590618 EcE24377A_3457 Escherichia coli E24377A IS621, transposase YP_001464454.1 3471876 D 331111 CDS YP_001464455.1 157155605 5588475 3472871..3472999 1 NC_009801.1 identified by glimmer; hypothetical protein 3472999 5588475 EcE24377A_3459 Escherichia coli E24377A hypothetical protein YP_001464455.1 3472871 D 331111 CDS YP_001464456.1 157155639 5589577 complement(3472978..3473226) 1 NC_009801.1 identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074; hydrogenase 2 accessory protein HypG 3473226 hybG 5589577 hybG Escherichia coli E24377A hydrogenase 2 accessory protein HypG YP_001464456.1 3472978 R 331111 CDS YP_001464457.1 157156506 5589172 complement(3473239..3473580) 1 NC_009801.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF 3473580 hypA2 5589172 hypA2 Escherichia coli E24377A hydrogenase nickel incorporation protein HybF YP_001464457.1 3473239 R 331111 CDS YP_001464458.1 157156988 5590432 complement(3473573..3474061) 1 NC_009801.1 hydrogenase 2-specific chaperone 3474061 hybE 5590432 hybE Escherichia coli E24377A hydrogenase 2-specific chaperone YP_001464458.1 3473573 R 331111 CDS YP_001464459.1 157156997 5590573 complement(3474054..3474548) 1 NC_009801.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase 3474548 hybD 5590573 hybD Escherichia coli E24377A hydrogenase 2 maturation endopeptidase YP_001464459.1 3474054 R 331111 CDS YP_001464460.1 157157766 5586442 complement(3474548..3476251) 1 NC_009801.1 involved in hydrogen uptake; hydrogenase 2 large subunit 3476251 hybC 5586442 hybC Escherichia coli E24377A hydrogenase 2 large subunit YP_001464460.1 3474548 R 331111 CDS YP_001464461.1 157158671 5588908 complement(3476248..3477426) 1 NC_009801.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit 3477426 hybB 5588908 hybB Escherichia coli E24377A hydrogenase 2 b cytochrome subunit YP_001464461.1 3476248 R 331111 CDS YP_001464462.1 157159045 5588531 complement(3477416..3478402) 1 NC_009801.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA 3478402 hybA 5588531 hybA Escherichia coli E24377A hydrogenase 2 protein HybA YP_001464462.1 3477416 R 331111 CDS YP_001464463.1 157158259 5587932 3477530..3478444 1 NC_009801.1 identified by glimmer; hypothetical protein 3478444 5587932 EcE24377A_3467 Escherichia coli E24377A hypothetical protein YP_001464463.1 3477530 D 331111 CDS YP_001464464.1 157157587 5588909 complement(3478405..3479523) 1 NC_009801.1 involved in hydrogen uptake; hydrogenase 2 small subunit 3479523 hyb0 5588909 hyb0 Escherichia coli E24377A hydrogenase 2 small subunit YP_001464464.1 3478405 R 331111 CDS YP_001464465.1 157158621 5590875 complement(3479712..3479999) 1 NC_009801.1 identified by similarity to SP:P64577; hypothetical protein 3479999 5590875 EcE24377A_3468 Escherichia coli E24377A hypothetical protein YP_001464465.1 3479712 R 331111 CDS YP_001464466.1 157159161 5586223 complement(3480118..3481005) 1 NC_009801.1 identified by match to protein family HMM PF01738; match to protein family HMM PF08840; dienelactone hydrolase 3481005 5586223 EcE24377A_3469 Escherichia coli E24377A dienelactone hydrolase YP_001464466.1 3480118 R 331111 CDS YP_001464467.1 157155999 5590607 3481163..3482203 1 NC_009801.1 identified by match to protein family HMM PF00248; aldo/keto reductase 3482203 5590607 EcE24377A_3470 Escherichia coli E24377A aldo/keto reductase YP_001464467.1 3481163 D 331111 CDS YP_001464468.1 157157804 5586622 complement(3482243..3482737) 1 NC_009801.1 identified by match to protein family HMM PF03350; match to protein family HMM TIGR00645; hypothetical protein 3482737 5586622 EcE24377A_3471 Escherichia coli E24377A hypothetical protein YP_001464468.1 3482243 R 331111 CDS YP_001464469.1 157156574 5588016 3482928..3483812 1 NC_009801.1 identified by match to protein family HMM PF00106; oxidoreductase 3483812 5588016 EcE24377A_3472 Escherichia coli E24377A oxidoreductase YP_001464469.1 3482928 D 331111 CDS YP_001464470.1 157157109 5588075 complement(3483885..3484076) 1 NC_009801.1 identified by glimmer; hypothetical protein 3484076 5588075 EcE24377A_3473 Escherichia coli E24377A hypothetical protein YP_001464470.1 3483885 R 331111 CDS YP_001464471.1 157158808 5587544 complement(3484084..3484509) 1 NC_009801.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD 3484509 exbD 5587544 exbD Escherichia coli E24377A biopolymer transport protein ExbD YP_001464471.1 3484084 R 331111 CDS YP_001464472.1 157156078 5588894 complement(3484516..3485250) 1 NC_009801.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB 3485250 exbB 5588894 exbB Escherichia coli E24377A biopolymer transport protein ExbB YP_001464472.1 3484516 R 331111 CDS YP_001464473.1 157158135 5590712 3485502..3486689 1 NC_009801.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3486689 metC 5590712 metC Escherichia coli E24377A cystathionine beta-lyase YP_001464473.1 3485502 D 331111 CDS YP_001464474.1 157157439 5585932 3486829..3487488 1 NC_009801.1 identified by similarity to SP:P0AA60; match to protein family HMM PF09335; hypothetical protein 3487488 5585932 EcE24377A_3477 Escherichia coli E24377A hypothetical protein YP_001464474.1 3486829 D 331111 CDS YP_001464475.1 157156780 5587362 complement(3487528..3488655) 1 NC_009801.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06719; AraC family transcriptional regulator 3488655 5587362 EcE24377A_3478 Escherichia coli E24377A AraC family transcriptional regulator YP_001464475.1 3487528 R 331111 CDS YP_001464476.1 157155817 5588639 3488621..3489784 1 NC_009801.1 identified by similarity to SP:Q46856; match to protein family HMM PF00465; alcohol dehydrogenase 3489784 yqhD 5588639 yqhD Escherichia coli E24377A alcohol dehydrogenase YP_001464476.1 3488621 D 331111 CDS YP_001464477.1 157157296 5586279 3489889..3490716 1 NC_009801.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3490716 dkgA 5586279 dkgA Escherichia coli E24377A 2,5-diketo-D-gluconate reductase A YP_001464477.1 3489889 D 331111 CDS YP_001464478.1 157158927 5589125 complement(3490860..3490952) 1 NC_009801.1 identified by glimmer; hypothetical protein 3490952 5589125 EcE24377A_3481 Escherichia coli E24377A hypothetical protein YP_001464478.1 3490860 R 331111 CDS YP_001464479.1 157156665 5586792 3490916..3491842 1 NC_009801.1 hypothetical protein 3491842 5586792 EcE24377A_3482 Escherichia coli E24377A hypothetical protein YP_001464479.1 3490916 D 331111 CDS YP_001464480.1 157155975 5589057 3491893..3492150 1 NC_009801.1 outer membrane lipoprotein 3492150 5589057 EcE24377A_3483 Escherichia coli E24377A outer membrane lipoprotein YP_001464480.1 3491893 D 331111 CDS YP_001464481.1 157155004 5587135 complement(3492193..3494412) 1 NC_009801.1 identified by match to protein family HMM PF04055; match to protein family HMM PF08497; hypothetical protein 3494412 5587135 EcE24377A_3484 Escherichia coli E24377A hypothetical protein YP_001464481.1 3492193 R 331111 CDS YP_001464482.1 157154923 5586593 complement(3494523..3495935) 1 NC_009801.1 identified by similarity to SP:P26648; match to protein family HMM PF07731; match to protein family HMM PF07732; match to protein family HMM TIGR01409; repressor protein for FtsI 3495935 sufI 5586593 sufI Escherichia coli E24377A repressor protein for FtsI YP_001464482.1 3494523 R 331111 CDS YP_001464483.1 157159047 5588525 complement(3496010..3496747) 1 NC_009801.1 identified by similarity to SP:P26647; match to protein family HMM PF01553; match to protein family HMM TIGR00530; 1-acyl-sn-glycerol-3-phosphate acyltransferase 3496747 plsC 5588525 plsC Escherichia coli E24377A 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_001464483.1 3496010 R 331111 CDS YP_001464484.1 157158561 5588900 complement(3496980..3499238) 1 NC_009801.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 3499238 parC 5588900 parC Escherichia coli E24377A DNA topoisomerase IV subunit A YP_001464484.1 3496980 R 331111 CDS YP_001464485.1 157157703 5589712 complement(3499784..3500266) 1 NC_009801.1 identified by match to protein family HMM PF06445; transcription activator effector binding domain/DNA gyrase inhibitor domain-containing protein 3500266 5589712 EcE24377A_3488 Escherichia coli E24377A transcription activator effector binding domain/DNA gyrase inhibitor domain-containing protein YP_001464485.1 3499784 R 331111 CDS YP_001464486.1 157157531 5586445 complement(3500319..3500711) 1 NC_009801.1 identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156; hypothetical protein 3500711 5586445 EcE24377A_3489 Escherichia coli E24377A hypothetical protein YP_001464486.1 3500319 R 331111 CDS YP_001464487.1 157158031 5589404 3500863..3501510 1 NC_009801.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3501510 qseB 5589404 qseB Escherichia coli E24377A DNA-binding transcriptional regulator QseB YP_001464487.1 3500863 D 331111 CDS YP_001464488.1 157156217 5589810 3501507..3502856 1 NC_009801.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor protein QseC 3502856 qseC 5589810 qseC Escherichia coli E24377A sensor protein QseC YP_001464488.1 3501507 D 331111 CDS YP_001464489.1 157156478 5590265 3503553..3504134 1 NC_009801.1 identified by similarity to SP:P0AEY5; match to protein family HMM PF02525; modulator of drug activity B 3504134 mdaB 5590265 mdaB Escherichia coli E24377A modulator of drug activity B YP_001464489.1 3503553 D 331111 CDS YP_001464490.1 157155790 5589085 3504165..3504479 1 NC_009801.1 identified by similarity to PDB:1R6Y_A; match to protein family HMM PF03992; quinol monooxygenase YgiN 3504479 ygiN 5589085 ygiN Escherichia coli E24377A quinol monooxygenase YgiN YP_001464490.1 3504165 D 331111 CDS YP_001464491.1 157159021 5590460 complement(3504527..3506419) 1 NC_009801.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 3506419 parE 5590460 parE Escherichia coli E24377A DNA topoisomerase IV subunit B YP_001464491.1 3504527 R 331111 CDS YP_001464492.1 157158315 5589424 complement(3506448..3507029) 1 NC_009801.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase 3507029 yqiA 5589424 yqiA Escherichia coli E24377A esterase YP_001464492.1 3506448 R 331111 CDS YP_001464493.1 157155509 5588515 complement(3507029..3507856) 1 NC_009801.1 identified by match to protein family HMM PF00149; match to protein family HMM PF08413; cyclic 3',5'-adenosine monophosphate phosphodiesterase 3507856 icc 5588515 icc Escherichia coli E24377A cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_001464493.1 3507029 R 331111 CDS YP_001464494.1 157154996 5590780 complement(3507881..3508303) 1 NC_009801.1 identified by similarity to SP:P0ADV0; match to protein family HMM PF06853; hypothetical protein 3508303 5590780 EcE24377A_3497 Escherichia coli E24377A hypothetical protein YP_001464494.1 3507881 R 331111 CDS YP_001464495.1 157157650 5588785 complement(3508304..3508933) 1 NC_009801.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase 3508933 nudF 5588785 nudF Escherichia coli E24377A ADP-ribose pyrophosphatase YP_001464495.1 3508304 R 331111 CDS YP_001464496.1 157156297 5587492 3509132..3510619 1 NC_009801.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3510619 tolC 5587492 tolC Escherichia coli E24377A outer membrane channel protein YP_001464496.1 3509132 D 331111 CDS YP_001464497.1 157158731 5589242 3510619..3510879 1 NC_009801.1 identified by similarity to GB:ABB63213.1; hypothetical protein 3510879 5589242 EcE24377A_3500 Escherichia coli E24377A hypothetical protein YP_001464497.1 3510619 D 331111 CDS YP_001464498.1 157158039 5590389 3510767..3511438 1 NC_009801.1 identified by similarity to GB:ABG71111.1; hypothetical protein 3511438 5590389 EcE24377A_3501 Escherichia coli E24377A hypothetical protein YP_001464498.1 3510767 D 331111 CDS YP_001464499.1 157156868 5586649 3511444..3512604 1 NC_009801.1 identified by match to protein family HMM PF03738; glutathionylspermidine synthase 3512604 5586649 EcE24377A_3502 Escherichia coli E24377A glutathionylspermidine synthase YP_001464499.1 3511444 D 331111 CDS YP_001464500.1 157156363 5590598 complement(3512642..3513457) 1 NC_009801.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein 3513457 5590598 EcE24377A_3503 Escherichia coli E24377A hypothetical protein YP_001464500.1 3512642 R 331111 CDS YP_001464501.1 157155777 5590025 3513573..3514346 1 NC_009801.1 identified by match to protein family HMM PF02535; zinc transporter ZupT 3514346 zupT 5590025 zupT Escherichia coli E24377A zinc transporter ZupT YP_001464501.1 3513573 D 331111 CDS YP_001464502.1 157155279 5590307 complement(3514404..3514598) 1 NC_009801.1 identified by similarity to GB:AAG58180.1; hypothetical protein 3514598 5590307 EcE24377A_3505 Escherichia coli E24377A hypothetical protein YP_001464502.1 3514404 R 331111 CDS YP_001464503.1 157156834 5590495 complement(3514835..3515488) 1 NC_009801.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 3515488 ribB 5590495 ribB Escherichia coli E24377A 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_001464503.1 3514835 R 331111 CDS YP_001464504.1 157155774 5586369 3515802..3516152 1 NC_009801.1 identified by match to protein family HMM PF04380; hypothetical protein 3516152 5586369 EcE24377A_3507 Escherichia coli E24377A hypothetical protein YP_001464504.1 3515802 D 331111 CDS YP_001464505.1 157156774 5586151 3516435..3516986 1 NC_009801.1 identified by match to protein family HMM PF00419; fimbrial protein 3516986 5586151 EcE24377A_3508 Escherichia coli E24377A fimbrial protein YP_001464505.1 3516435 D 331111 CDS YP_001464506.1 157156206 5589191 3517046..3519550 1 NC_009801.1 identified by match to protein family HMM PF00577; fimbrial usher protein 3519550 5589191 EcE24377A_3509 Escherichia coli E24377A fimbrial usher protein YP_001464506.1 3517046 D 331111 CDS YP_001464507.1 157156800 5587415 3519566..3520315 1 NC_009801.1 identified by match to protein family HMM PF00345; periplasmic pilus chaperone family protein 3520315 5587415 EcE24377A_3510 Escherichia coli E24377A periplasmic pilus chaperone family protein YP_001464507.1 3519566 D 331111 CDS YP_001464508.1 157156079 5587714 3520317..3521381 1 NC_009801.1 identified by similarity to GB:AAZ89767.1; hypothetical protein 3521381 5587714 EcE24377A_3511 Escherichia coli E24377A hypothetical protein YP_001464508.1 3520317 D 331111 CDS YP_001464509.1 157155406 5588770 complement(3521424..3521624) 1 NC_009801.1 Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS 3521624 glgS 5588770 glgS Escherichia coli E24377A glycogen synthesis protein GlgS YP_001464509.1 3521424 R 331111 CDS YP_001464510.1 157154717 5587603 3521893..3522522 1 NC_009801.1 identified by match to protein family HMM PF07290; inner membrane protein 3522522 5587603 EcE24377A_3513 Escherichia coli E24377A inner membrane protein YP_001464510.1 3521893 D 331111 CDS YP_001464511.1 157157664 5588974 3522549..3524210 1 NC_009801.1 identified by match to protein family HMM PF01145; hypothetical protein 3524210 5588974 EcE24377A_3514 Escherichia coli E24377A hypothetical protein YP_001464511.1 3522549 D 331111 CDS YP_001464512.1 157159264 5590809 complement(3525004..3526437) 1 NC_009801.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 3526437 hldE 5590809 hldE Escherichia coli E24377A bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_001464512.1 3525004 R 331111 CDS YP_001464513.1 157156240 5587885 complement(3526485..3529325) 1 NC_009801.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 3529325 glnE 5587885 glnE Escherichia coli E24377A bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_001464513.1 3526485 R 331111 CDS YP_001464514.1 157157988 5586610 complement(3529348..3530649) 1 NC_009801.1 identified by match to protein family HMM PF01928; match to protein family HMM PF05235; adenylate cyclase 3530649 5586610 EcE24377A_3517 Escherichia coli E24377A adenylate cyclase YP_001464514.1 3529348 R 331111 CDS YP_001464515.1 157158504 5586143 3530891..3531511 1 NC_009801.1 signal transduction protein 3531511 5586143 EcE24377A_3518 Escherichia coli E24377A signal transduction protein YP_001464515.1 3530891 D 331111 CDS YP_001464516.1 157155570 5589556 3531575..3532813 1 NC_009801.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3532813 cca 5589556 cca Escherichia coli E24377A multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_001464516.1 3531575 D 331111 CDS YP_001464517.1 157159195 5589698 complement(3532976..3533797) 1 NC_009801.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 3533797 uppP 5589698 uppP Escherichia coli E24377A undecaprenyl pyrophosphate phosphatase YP_001464517.1 3532976 R 331111 CDS YP_001464518.1 157158662 5589115 complement(3533887..3534255) 1 NC_009801.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 3534255 folB 5589115 folB Escherichia coli E24377A bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase YP_001464518.1 3533887 R 331111 CDS YP_001464519.1 157156897 5587348 3534360..3534977 1 NC_009801.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 3534977 5587348 EcE24377A_3522 Escherichia coli E24377A glycerol-3-phosphate acyltransferase PlsY YP_001464519.1 3534360 D 331111 CDS YP_001464520.1 157156353 5589029 complement(3534990..3535922) 1 NC_009801.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR 3535922 5589029 EcE24377A_3523 Escherichia coli E24377A transcriptional activator TtdR YP_001464520.1 3534990 R 331111 CDS YP_001464521.1 157155795 5587014 3535941..3536075 1 NC_009801.1 identified by glimmer; hypothetical protein 3536075 5587014 EcE24377A_3524 Escherichia coli E24377A hypothetical protein YP_001464521.1 3535941 D 331111 CDS YP_001464522.1 157154732 5587616 3536129..3537040 1 NC_009801.1 Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3537040 ddtA 5587616 ddtA Escherichia coli E24377A tartrate dehydratase subunit alpha YP_001464522.1 3536129 D 331111 CDS YP_001464523.1 157158916 5590824 3537037..3537642 1 NC_009801.1 Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3537642 ttdB 5590824 ttdB Escherichia coli E24377A L(+)-tartrate dehydratase subunit beta YP_001464523.1 3537037 D 331111 CDS YP_001464524.1 157158489 5590565 3537691..3539154 1 NC_009801.1 identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785; anion transporter 3539154 5590565 EcE24377A_3527 Escherichia coli E24377A anion transporter YP_001464524.1 3537691 D 331111 CDS YP_001464525.1 157157805 5588002 complement(3539197..3540210) 1 NC_009801.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 3540210 gcp 5588002 gcp Escherichia coli E24377A DNA-binding/iron metalloprotein/AP endonuclease YP_001464525.1 3539197 R 331111 CDS YP_001464526.1 157156151 5589126 3540448..3540663 1 NC_009801.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3540663 rpsU 5589126 rpsU Escherichia coli E24377A 30S ribosomal protein S21 YP_001464526.1 3540448 D 331111 CDS YP_001464527.1 157156565 5587754 3540774..3542519 1 NC_009801.1 synthesizes RNA primers at the replication forks; DNA primase 3542519 dnaG 5587754 dnaG Escherichia coli E24377A DNA primase YP_001464527.1 3540774 D 331111 CDS YP_001464528.1 157155497 5589910 3542714..3544555 1 NC_009801.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3544555 rpoD 5589910 rpoD Escherichia coli E24377A RNA polymerase sigma factor RpoD YP_001464528.1 3542714 D 331111 CDS YP_001464529.1 157158797 5590035 complement(3544633..3545139) 1 NC_009801.1 identified by similarity to SP:P0A9H1; match to protein family HMM PF03167; G/U mismatch-specific DNA glycosylase 3545139 mug 5590035 mug Escherichia coli E24377A G/U mismatch-specific DNA glycosylase YP_001464529.1 3544633 R 331111 CDS YP_001464530.1 157158074 5586284 complement(3545393..3546157) 1 NC_009801.1 identified by match to protein family HMM PF04954; match to protein family HMM PF08021; siderophore-interacting protein 3546157 5586284 EcE24377A_3535 Escherichia coli E24377A siderophore-interacting protein YP_001464530.1 3545393 R 331111 CDS YP_001464531.1 157156435 5589218 3546208..3546315 1 NC_009801.1 identified by glimmer; hypothetical protein 3546315 5589218 EcE24377A_3536 Escherichia coli E24377A hypothetical protein YP_001464531.1 3546208 D 331111 CDS YP_001464532.1 157156153 5590000 3546434..3547057 1 NC_009801.1 identified by match to protein family HMM PF03551; PadR family transcriptional regulator 3547057 5590000 EcE24377A_3537 Escherichia coli E24377A PadR family transcriptional regulator YP_001464532.1 3546434 D 331111 CDS YP_001464533.1 157155066 5585923 complement(3547211..3548731) 1 NC_009801.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF08447; match to protein family HMM TIGR00229; aerotaxis receptor 3548731 aer 5585923 aer Escherichia coli E24377A aerotaxis receptor YP_001464533.1 3547211 R 331111 CDS YP_001464534.1 157158357 5587056 complement(3548922..3549035) 1 NC_009801.1 identified by glimmer; hypothetical protein 3549035 5587056 EcE24377A_3539 Escherichia coli E24377A hypothetical protein YP_001464534.1 3548922 R 331111 CDS YP_001464535.1 157158854 5586935 3549239..3550528 1 NC_009801.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3550528 rocD 5586935 rocD Escherichia coli E24377A putrescine--2-oxoglutarate aminotransferase YP_001464535.1 3549239 D 331111 CDS YP_001464536.1 157157366 5589883 complement(3550570..3550902) 1 NC_009801.1 identified by match to protein family HMM PF01588; hypothetical protein 3550902 5589883 EcE24377A_3541 Escherichia coli E24377A hypothetical protein YP_001464536.1 3550570 R 331111 CDS YP_001464537.1 157157845 5587470 3551121..3552104 1 NC_009801.1 identified by similarity to SP:P06846; match to protein family HMM PF00356; match to protein family HMM PF00532; DNA-binding transcriptional repressor EbgR 3552104 ebgR 5587470 ebgR Escherichia coli E24377A DNA-binding transcriptional repressor EbgR YP_001464537.1 3551121 D 331111 CDS YP_001464538.1 157158539 5587097 3552288..3555380 1 NC_009801.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3555380 ebgA 5587097 ebgA Escherichia coli E24377A cryptic beta-D-galactosidase subunit alpha YP_001464538.1 3552288 D 331111 CDS YP_001464539.1 157155641 5587854 3555377..3555826 1 NC_009801.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3555826 ebgC 5587854 ebgC Escherichia coli E24377A cryptic beta-D-galactosidase subunit beta YP_001464539.1 3555377 D 331111 CDS YP_001464540.1 157154777 5589174 3555889..3557322 1 NC_009801.1 identified by match to protein family HMM PF00324; amino acid permease 3557322 5589174 EcE24377A_3545 Escherichia coli E24377A amino acid permease YP_001464540.1 3555889 D 331111 CDS YP_001464541.1 157155132 5590806 3557456..3558526 1 NC_009801.1 identified by similarity to GB:AAZ89711.1; hypothetical protein 3558526 5590806 EcE24377A_3546 Escherichia coli E24377A hypothetical protein YP_001464541.1 3557456 D 331111 CDS YP_001464542.1 157157505 5586281 3558543..3560894 1 NC_009801.1 identified by similarity to SP:P42592; glycosyl hydrolase 3560894 5586281 EcE24377A_3547 Escherichia coli E24377A glycosyl hydrolase YP_001464542.1 3558543 D 331111 CDS YP_001464543.1 157159338 5588147 3561220..3563238 1 NC_009801.1 identified by similarity to SP:P42593; match to protein family HMM PF00724; match to protein family HMM PF01266; match to protein family HMM PF07992; 2,4-dienoyl-CoA reductase 3563238 fadH 5588147 fadH Escherichia coli E24377A 2,4-dienoyl-CoA reductase YP_001464543.1 3561220 D 331111 CDS YP_001464544.1 157156464 5589630 complement(3563283..3563699) 1 NC_009801.1 identified by match to protein family HMM PF01381; helix-turn-helix DNA-binding domain-containing protein 3563699 5589630 EcE24377A_3549 Escherichia coli E24377A helix-turn-helix DNA-binding domain-containing protein YP_001464544.1 3563283 R 331111 CDS YP_001464545.1 157155932 5590790 complement(3563696..3563866) 1 NC_009801.1 identified by similarity to GB:AAN82286.1; hypothetical protein 3563866 5590790 EcE24377A_3550 Escherichia coli E24377A hypothetical protein YP_001464545.1 3563696 R 331111 CDS YP_001464546.1 157157132 5586732 complement(3563970..3565106) 1 NC_009801.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08242; methyltransferase 3565106 5586732 EcE24377A_3551 Escherichia coli E24377A methyltransferase YP_001464546.1 3563970 R 331111 CDS YP_001464547.1 157157773 5589985 3565191..3565694 1 NC_009801.1 identified by similarity to SP:P42597; match to protein family HMM PF01863; hypothetical protein 3565694 5589985 EcE24377A_3552 Escherichia coli E24377A hypothetical protein YP_001464547.1 3565191 D 331111 CDS YP_001464548.1 157158500 5588535 3565771..3566454 1 NC_009801.1 identified by match to protein family HMM PF02698; SanA protein 3566454 5588535 EcE24377A_3553 Escherichia coli E24377A SanA protein YP_001464548.1 3565771 D 331111 CDS YP_001464549.1 157159143 5588617 3566533..3567519 1 NC_009801.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase, NAD binding 3567519 5588617 EcE24377A_3554 Escherichia coli E24377A oxidoreductase, NAD binding YP_001464549.1 3566533 D 331111 CDS YP_001464550.1 157156139 5590742 3567802..3568767 1 NC_009801.1 identified by similarity to SP:P42601; match to protein family HMM PF03741; protein Alx 3568767 alx 5590742 alx Escherichia coli E24377A protein Alx YP_001464550.1 3567802 D 331111 CDS YP_001464551.1 157155606 5587403 3568876..3569178 1 NC_009801.1 identified by glimmer; hypothetical protein 3569178 5587403 EcE24377A_3556 Escherichia coli E24377A hypothetical protein YP_001464551.1 3568876 D 331111 CDS YP_001464552.1 157157489 5587934 3569383..3570627 1 NC_009801.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3570627 sstT 5587934 sstT Escherichia coli E24377A serine/threonine transporter SstT YP_001464552.1 3569383 D 331111 CDS YP_001464553.1 157156983 5589038 complement(3570632..3571183) 1 NC_009801.1 inner membrane protein 3571183 5589038 EcE24377A_3558 Escherichia coli E24377A inner membrane protein YP_001464553.1 3570632 R 331111 CDS YP_001464554.1 157156001 5589597 complement(3571266..3572753) 1 NC_009801.1 identified by similarity to SP:P42604; match to protein family HMM PF04295; match to protein family HMM PF08666; altronate dehydratase 3572753 uxaA 5589597 uxaA Escherichia coli E24377A altronate dehydratase YP_001464554.1 3571266 R 331111 CDS YP_001464555.1 157155304 5589846 complement(3572768..3574180) 1 NC_009801.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 3574180 uxaC 5589846 uxaC Escherichia coli E24377A glucuronate isomerase YP_001464555.1 3572768 R 331111 CDS YP_001464556.1 157157575 5586588 3574663..3575961 1 NC_009801.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893; hexuronate transporter 3575961 5586588 EcE24377A_3561 Escherichia coli E24377A hexuronate transporter YP_001464556.1 3574663 D 331111 CDS YP_001464557.1 157157077 5587527 complement(3576049..3577137) 1 NC_009801.1 pilus biogenesis initiator protein 3577137 5587527 EcE24377A_3562 Escherichia coli E24377A pilus biogenesis initiator protein YP_001464557.1 3576049 R 331111 CDS YP_001464558.1 157158530 5590766 complement(3577134..3579836) 1 NC_009801.1 hypothetical protein 3579836 5590766 EcE24377A_3563 Escherichia coli E24377A hypothetical protein YP_001464558.1 3577134 R 331111 CDS YP_001464559.1 157158024 5587519 complement(3579910..3580410) 1 NC_009801.1 identified by match to protein family HMM PF04449; CS1 type fimbrial major subunit 3580410 5587519 EcE24377A_3564 Escherichia coli E24377A CS1 type fimbrial major subunit YP_001464559.1 3579910 R 331111 CDS YP_001464560.1 157155469 5589785 complement(3580440..3581156) 1 NC_009801.1 hypothetical protein 3581156 5589785 EcE24377A_3565 Escherichia coli E24377A hypothetical protein YP_001464560.1 3580440 R 331111 CDS YP_001464561.1 157154963 5590003 3581452..3582228 1 NC_009801.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3582228 exuR 5590003 exuR Escherichia coli E24377A DNA-binding transcriptional repressor ExuR YP_001464561.1 3581452 D 331111 CDS YP_001464562.1 157156585 5590092 3582573..3583235 1 NC_009801.1 identified by similarity to SP:P0AA63; match to protein family HMM PF09335; inner membrane protein 3583235 5590092 EcE24377A_3567 Escherichia coli E24377A inner membrane protein YP_001464562.1 3582573 D 331111 CDS YP_001464563.1 157154826 5587954 3583239..3583622 1 NC_009801.1 identified by similarity to GB:AAZ89832.1; hypothetical protein 3583622 5587954 EcE24377A_3569 Escherichia coli E24377A hypothetical protein YP_001464563.1 3583239 D 331111 CDS YP_001464564.1 157156009 5586627 complement(3583607..3583702) 1 NC_009801.1 identified by glimmer; hypothetical protein 3583702 5586627 EcE24377A_3568 Escherichia coli E24377A hypothetical protein YP_001464564.1 3583607 R 331111 CDS YP_001464565.1 157156717 5587099 3583769..3584137 1 NC_009801.1 identified by similarity to SP:P42616; match to protein family HMM PF06476; hypothetical protein 3584137 5587099 EcE24377A_3570 Escherichia coli E24377A hypothetical protein YP_001464565.1 3583769 D 331111 CDS YP_001464566.1 157159454 5589874 3584175..3584480 1 NC_009801.1 identified by similarity to GB:CAD07753.1; match to protein family HMM PF05957; hypothetical protein 3584480 5589874 EcE24377A_3571 Escherichia coli E24377A hypothetical protein YP_001464566.1 3584175 D 331111 CDS YP_001464567.1 157155345 5587152 3584483..3584887 1 NC_009801.1 identified by similarity to GB:ABE08983.1; hypothetical protein 3584887 5587152 EcE24377A_3572 Escherichia coli E24377A hypothetical protein YP_001464567.1 3584483 D 331111 CDS YP_001464568.1 157158242 5588853 3584877..3585176 1 NC_009801.1 identified by similarity to GB:ABB63285.1; hypothetical protein 3585176 5588853 EcE24377A_3573 Escherichia coli E24377A hypothetical protein YP_001464568.1 3584877 D 331111 CDS YP_001464569.1 157157553 5587229 3585362..3585754 1 NC_009801.1 identified by match to protein family HMM PF07681; inner membrane protein YqjF 3585754 5587229 EcE24377A_3574 Escherichia coli E24377A inner membrane protein YqjF YP_001464569.1 3585362 D 331111 CDS YP_001464570.1 157157849 5586997 3585824..3586810 1 NC_009801.1 hypothetical protein 3586810 5586997 EcE24377A_3575 Escherichia coli E24377A hypothetical protein YP_001464570.1 3585824 D 331111 CDS YP_001464571.1 157157177 5587522 3586850..3586945 1 NC_009801.1 identified by glimmer; hypothetical protein 3586945 5587522 EcE24377A_3576 Escherichia coli E24377A hypothetical protein YP_001464571.1 3586850 D 331111 CDS YP_001464572.1 157156826 5587289 3587082..3587468 1 NC_009801.1 identified by match to protein family HMM PF05656; inner membrane protein YhaH 3587468 5587289 EcE24377A_3577 Escherichia coli E24377A inner membrane protein YhaH YP_001464572.1 3587082 D 331111 CDS YP_001464573.1 157156133 5586528 3587561..3587653 1 NC_009801.1 identified by glimmer; hypothetical protein 3587653 5586528 EcE24377A_3578 Escherichia coli E24377A hypothetical protein YP_001464573.1 3587561 D 331111 CDS YP_001464574.1 157155090 5587786 3587710..3588066 1 NC_009801.1 identified by similarity to SP:P64592; match to protein family HMM PF05656; inner membrane protein 3588066 5587786 EcE24377A_3579 Escherichia coli E24377A inner membrane protein YP_001464574.1 3587710 D 331111 CDS YP_001464575.1 157155809 5588685 complement(3588117..3589013) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 3589013 5588685 EcE24377A_3580 Escherichia coli E24377A LysR family transcriptional regulator YP_001464575.1 3588117 R 331111 CDS YP_001464576.1 157157998 5586237 3589118..3589819 1 NC_009801.1 identified by match to protein family HMM PF02678; pirin 3589819 5586237 EcE24377A_3581 Escherichia coli E24377A pirin YP_001464576.1 3589118 D 331111 CDS YP_001464577.1 157158430 5588336 3589842..3590006 1 NC_009801.1 identified by similarity to GB:ABB63296.1; hypothetical protein 3590006 5588336 EcE24377A_3583 Escherichia coli E24377A hypothetical protein YP_001464577.1 3589842 D 331111 CDS YP_001464578.1 157157910 5589058 complement(3589996..3590148) 1 NC_009801.1 identified by glimmer; hypothetical protein 3590148 5589058 EcE24377A_3582 Escherichia coli E24377A hypothetical protein YP_001464578.1 3589996 R 331111 CDS YP_001464579.1 157158949 5588443 complement(3590218..3591528) 1 NC_009801.1 identified by match to protein family HMM PF06354; hypothetical protein 3591528 5588443 EcE24377A_3584 Escherichia coli E24377A hypothetical protein YP_001464579.1 3590218 R 331111 CDS YP_001464580.1 157155356 5587851 complement(3591556..3592887) 1 NC_009801.1 identified by match to protein family HMM TIGR00814; serine transporter family protein 3592887 5587851 EcE24377A_3585 Escherichia coli E24377A serine transporter family protein YP_001464580.1 3591556 R 331111 CDS YP_001464581.1 157158880 5587893 complement(3593162..3594526) 1 NC_009801.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; L-serine dehydratase tdcG 3594526 tdcG 5587893 tdcG Escherichia coli E24377A L-serine dehydratase tdcG YP_001464581.1 3593162 R 331111 CDS YP_001464582.1 157157021 5588795 complement(3594598..3594987) 1 NC_009801.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; hypothetical protein 3594987 5588795 EcE24377A_3587 Escherichia coli E24377A hypothetical protein YP_001464582.1 3594598 R 331111 CDS YP_001464583.1 157155072 5586576 complement(3595001..3597295) 1 NC_009801.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; formate acetyltransferase 3597295 pflB1 5586576 pflB1 Escherichia coli E24377A formate acetyltransferase YP_001464583.1 3595001 R 331111 CDS YP_001464584.1 157156881 5587771 complement(3597329..3598537) 1 NC_009801.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase 3598537 tdcD 5587771 tdcD Escherichia coli E24377A propionate/acetate kinase YP_001464584.1 3597329 R 331111 CDS YP_001464585.1 157154888 5589804 complement(3598563..3599894) 1 NC_009801.1 involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC 3599894 tdcC 5589804 tdcC Escherichia coli E24377A threonine/serine transporter TdcC YP_001464585.1 3598563 R 331111 CDS YP_001464586.1 157157461 5590034 complement(3599916..3600905) 1 NC_009801.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase 3600905 tdcB 5590034 tdcB Escherichia coli E24377A threonine dehydratase YP_001464586.1 3599916 R 331111 CDS YP_001464587.1 157158128 5590149 complement(3601004..3601942) 1 NC_009801.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA 3601942 tdcA 5590149 tdcA Escherichia coli E24377A DNA-binding transcriptional activator TdcA YP_001464587.1 3601004 R 331111 CDS YP_001464588.1 157158804 5586043 3602257..3602475 1 NC_009801.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3602475 tdcR 5586043 tdcR Escherichia coli E24377A DNA-binding transcriptional activator TdcR YP_001464588.1 3602257 D 331111 CDS YP_001464589.1 157159416 5589244 complement(3602557..3602694) 1 NC_009801.1 identified by glimmer; hypothetical protein 3602694 5589244 EcE24377A_3594 Escherichia coli E24377A hypothetical protein YP_001464589.1 3602557 R 331111 CDS YP_001464590.1 157158794 5590343 3602710..3603270 1 NC_009801.1 identified by glimmer; hypothetical protein 3603270 5590343 EcE24377A_3595 Escherichia coli E24377A hypothetical protein YP_001464590.1 3602710 D 331111 CDS YP_001464591.1 157158281 5588145 3603292..3604479 1 NC_009801.1 identified by similarity to GB:BAB37424.1; hypothetical protein 3604479 5588145 EcE24377A_3596 Escherichia coli E24377A hypothetical protein YP_001464591.1 3603292 D 331111 CDS YP_001464592.1 157155918 5589287 3604540..3604704 1 NC_009801.1 identified by similarity to GB:ABB67500.1; hypothetical protein 3604704 5589287 EcE24377A_3599 Escherichia coli E24377A hypothetical protein YP_001464592.1 3604540 D 331111 CDS YP_001464593.1 157155192 5589582 3604756..3604863 1 NC_009801.1 identified by glimmer; hypothetical protein 3604863 5589582 EcE24377A_3600 Escherichia coli E24377A hypothetical protein YP_001464593.1 3604756 D 331111 CDS YP_001464595.1 157157513 5589559 complement(3605502..3606647) 1 NC_009801.1 identified by similarity to SP:P23524; match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase 3606647 garK 5589559 garK Escherichia coli E24377A glycerate kinase YP_001464595.1 3605502 R 331111 CDS YP_001464596.1 157156726 5588960 complement(3606744..3607628) 1 NC_009801.1 catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase 3607628 garR 5588960 garR Escherichia coli E24377A tartronate semialdehyde reductase YP_001464596.1 3606744 R 331111 CDS YP_001464597.1 157156168 5589352 complement(3607664..3608434) 1 NC_009801.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase 3608434 garL 5589352 garL Escherichia coli E24377A alpha-dehydro-beta-deoxy-D-glucarate aldolase YP_001464597.1 3607664 R 331111 CDS YP_001464598.1 157155355 5589562 complement(3608450..3609784) 1 NC_009801.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893; galactarate permease GarP 3609784 garP 5589562 garP Escherichia coli E24377A galactarate permease GarP YP_001464598.1 3608450 R 331111 CDS YP_001464599.1 157157018 5587892 3609771..3609884 1 NC_009801.1 identified by glimmer; hypothetical protein 3609884 5587892 EcE24377A_3606 Escherichia coli E24377A hypothetical protein YP_001464599.1 3609771 D 331111 CDS YP_001464600.1 157158601 5589879 3609993..3610112 1 NC_009801.1 identified by glimmer; hypothetical protein 3610112 5589879 EcE24377A_3607 Escherichia coli E24377A hypothetical protein YP_001464600.1 3609993 D 331111 CDS YP_001464601.1 157155663 5586967 3610159..3611730 1 NC_009801.1 identified by similarity to SP:P39829; match to protein family HMM PF04295; match to protein family HMM PF08666; galactarate dehydratase 3611730 garD 5586967 garD Escherichia coli E24377A galactarate dehydratase YP_001464601.1 3610159 D 331111 CDS YP_001464602.1 157157526 5587743 3611879..3612214 1 NC_009801.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; regulator PrlF 3612214 sohA 5587743 sohA Escherichia coli E24377A regulator PrlF YP_001464602.1 3611879 D 331111 CDS YP_001464603.1 157158522 5589554 3612214..3612678 1 NC_009801.1 identified by similarity to GB:AAZ89862.1; hypothetical protein 3612678 5589554 EcE24377A_3610 Escherichia coli E24377A hypothetical protein YP_001464603.1 3612214 D 331111 CDS YP_001464604.1 157158868 5587805 complement(3612733..3613542) 1 NC_009801.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR 3613542 5587805 EcE24377A_3611 Escherichia coli E24377A DNA-binding transcriptional regulator AgaR YP_001464604.1 3612733 R 331111 CDS YP_001464605.1 157159242 5587313 3613791..3615071 1 NC_009801.1 identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810; D-tagatose-bisphosphate aldolase non-catalytic subunit 3615071 5587313 EcE24377A_3612 Escherichia coli E24377A D-tagatose-bisphosphate aldolase non-catalytic subunit YP_001464605.1 3613791 D 331111 CDS YP_001464606.1 157154712 5590797 3615094..3615567 1 NC_009801.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3615567 agaV 5590797 agaV Escherichia coli E24377A PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_001464606.1 3615094 D 331111 CDS YP_001464607.1 157155380 5586879 3615578..3616357 1 NC_009801.1 identified by match to protein family HMM PF03609; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3616357 agaW 5586879 agaW Escherichia coli E24377A PTS system N-acetylgalactosamine-specific transporter subunit IIC YP_001464607.1 3615578 D 331111 CDS YP_001464608.1 157157159 5587564 3616347..3617225 1 NC_009801.1 identified by match to protein family HMM PF03613; PTS system N-acetylgalactosamine-specific, IID component 3617225 agaE 5587564 agaE Escherichia coli E24377A PTS system N-acetylgalactosamine-specific, IID component YP_001464608.1 3616347 D 331111 CDS YP_001464609.1 157157806 5588610 3617243..3617677 1 NC_009801.1 identified by similarity to GB:AAF81086.1; match to protein family HMM PF03610; PTS system mannose/sorbose-specific transporter subunit IIA 3617677 agaF 5588610 agaF Escherichia coli E24377A PTS system mannose/sorbose-specific transporter subunit IIA YP_001464609.1 3617243 D 331111 CDS YP_001464610.1 157158122 5589127 3617674..3618807 1 NC_009801.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221; N-acetylglucosamine-6-phosphate deacetylase 3618807 nagA2 5589127 nagA2 Escherichia coli E24377A N-acetylglucosamine-6-phosphate deacetylase YP_001464610.1 3617674 D 331111 CDS YP_001464611.1 157159084 5590112 3619157..3620311 1 NC_009801.1 identified by match to protein family HMM PF01380; match to protein family HMM TIGR02815; AgaS family sugar isomerase 3620311 5590112 EcE24377A_3618 Escherichia coli E24377A AgaS family sugar isomerase YP_001464611.1 3619157 D 331111 CDS YP_001464612.1 157156052 5587992 3620324..3621184 1 NC_009801.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3621184 kbaY 5587992 kbaY Escherichia coli E24377A tagatose-bisphosphate aldolase YP_001464612.1 3620324 D 331111 CDS YP_001464613.1 157157032 5588353 3621351..3621827 1 NC_009801.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3621827 agaB 5588353 agaB Escherichia coli E24377A PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_001464613.1 3621351 D 331111 CDS YP_001464614.1 157157847 5586234 3621866..3622669 1 NC_009801.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3622669 agaC 5586234 agaC Escherichia coli E24377A PTS system N-acetylgalactosamine-specific transporter subunit IIC YP_001464614.1 3621866 D 331111 CDS YP_001464615.1 157158576 5587520 3622659..3623450 1 NC_009801.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 3623450 agaD 5587520 agaD Escherichia coli E24377A PTS system N-acetylgalactosamine-specific transporter subunit IID YP_001464615.1 3622659 D 331111 CDS YP_001464616.1 157155041 5588476 3623451..3624206 1 NC_009801.1 identified by match to protein family HMM PF01182; galactosamine-6-phosphate isomerase 3624206 agaI 5588476 agaI Escherichia coli E24377A galactosamine-6-phosphate isomerase YP_001464616.1 3623451 D 331111 CDS YP_001464617.1 157154900 5590642 3624606..3625190 1 NC_009801.1 identified by match to protein family HMM PF00419; fimbrial protein 3625190 5590642 EcE24377A_3624 Escherichia coli E24377A fimbrial protein YP_001464617.1 3624606 D 331111 CDS YP_001464618.1 157155860 5586174 3625270..3625965 1 NC_009801.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; pili assembly chaperone protein 3625965 5586174 EcE24377A_3625 Escherichia coli E24377A pili assembly chaperone protein YP_001464618.1 3625270 D 331111 CDS YP_001464619.1 157156256 5587988 3625995..3628511 1 NC_009801.1 identified by match to protein family HMM PF00577; fimbrial usher family protein 3628511 5587988 EcE24377A_3626 Escherichia coli E24377A fimbrial usher family protein YP_001464619.1 3625995 D 331111 CDS YP_001464620.1 157156670 5590358 3628522..3629613 1 NC_009801.1 fimbrial protein 3629613 5590358 EcE24377A_3627 Escherichia coli E24377A fimbrial protein YP_001464620.1 3628522 D 331111 CDS YP_001464621.1 157157560 5588956 complement(3629656..3630516) 1 NC_009801.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096; tetrapyrrole methylase 3630516 5588956 EcE24377A_3628 Escherichia coli E24377A tetrapyrrole methylase YP_001464621.1 3629656 R 331111 CDS YP_001464622.1 157156302 5589385 3630580..3632616 1 NC_009801.1 identified by match to protein family HMM PF04348; lipoprotein 3632616 5589385 EcE24377A_3629 Escherichia coli E24377A lipoprotein YP_001464622.1 3630580 D 331111 CDS YP_001464623.1 157155794 5588776 3632574..3632969 1 NC_009801.1 identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252; hypothetical protein 3632969 5588776 EcE24377A_3630 Escherichia coli E24377A hypothetical protein YP_001464623.1 3632574 D 331111 CDS YP_001464624.1 157155255 5587615 3632989..3633579 1 NC_009801.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3633579 diaA 5587615 diaA Escherichia coli E24377A DnaA initiator-associating protein DiaA YP_001464624.1 3632989 D 331111 CDS YP_001464625.1 157158432 5589224 3633589..3634164 1 NC_009801.1 identified by match to protein family HMM PF04972; hypothetical protein 3634164 5589224 EcE24377A_3632 Escherichia coli E24377A hypothetical protein YP_001464625.1 3633589 D 331111 CDS YP_001464626.1 157156270 5587595 complement(3635390..3636025) 1 NC_009801.1 identified by match to protein family HMM PF01370; NAD dependent epimerase/dehydratase 3636025 5587595 EcE24377A_3634 Escherichia coli E24377A NAD dependent epimerase/dehydratase YP_001464626.1 3635390 R 331111 CDS YP_001464627.1 157155250 5590554 3636153..3636671 1 NC_009801.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382; PfpI family intracellular peptidase 3636671 5590554 EcE24377A_3636 Escherichia coli E24377A PfpI family intracellular peptidase YP_001464627.1 3636153 D 331111 CDS YP_001464628.1 157155735 5589669 complement(3636651..3637094) 1 NC_009801.1 identified by similarity to GB:AAV78968.1; hypothetical protein 3637094 5589669 EcE24377A_3635 Escherichia coli E24377A hypothetical protein YP_001464628.1 3636651 R 331111 CDS YP_001464629.1 157159236 5590865 3637145..3637447 1 NC_009801.1 identified by match to protein family HMM PF01541; GIY-YIG nuclease superfamily protein 3637447 5590865 EcE24377A_3638 Escherichia coli E24377A GIY-YIG nuclease superfamily protein YP_001464629.1 3637145 D 331111 CDS YP_001464630.1 157155251 5590280 complement(3637434..3637937) 1 NC_009801.1 identified by match to protein family HMM PF00583; acetyltransferase 3637937 5590280 EcE24377A_3637 Escherichia coli E24377A acetyltransferase YP_001464630.1 3637434 R 331111 CDS YP_001464631.1 157158003 5589670 complement(3637931..3638455) 1 NC_009801.1 identified by match to protein family HMM PF02036; sterol-binding protein 3638455 5589670 EcE24377A_3639 Escherichia coli E24377A sterol-binding protein YP_001464631.1 3637931 R 331111 CDS YP_001464632.1 157157832 5590500 3638664..3639659 1 NC_009801.1 identified by match to protein family HMM PF01136; U32 family peptidase 3639659 5590500 EcE24377A_3640 Escherichia coli E24377A U32 family peptidase YP_001464632.1 3638664 D 331111 CDS YP_001464633.1 157157364 5588433 3639668..3640546 1 NC_009801.1 identified by match to protein family HMM PF01136; U32 family peptidase 3640546 5588433 EcE24377A_3641 Escherichia coli E24377A U32 family peptidase YP_001464633.1 3639668 D 331111 CDS YP_001464634.1 157156548 5587077 3640752..3641759 1 NC_009801.1 identified by match to protein family HMM PF00296; hypothetical protein 3641759 5587077 EcE24377A_3642 Escherichia coli E24377A hypothetical protein YP_001464634.1 3640752 D 331111 CDS YP_001464635.1 157155336 5586318 complement(3641877..3643121) 1 NC_009801.1 tryptophan transporter of high affinity; tryptophan permease 3643121 mtr 5586318 mtr Escherichia coli E24377A tryptophan permease YP_001464635.1 3641877 R 331111 CDS YP_001464636.1 157154820 5590031 complement(3643275..3645230) 1 NC_009801.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD 3645230 deaD 5590031 deaD Escherichia coli E24377A ATP-dependent RNA helicase DeaD YP_001464636.1 3643275 R 331111 CDS YP_001464637.1 157158619 5586921 3645304..3645459 1 NC_009801.1 identified by glimmer; hypothetical protein 3645459 5586921 EcE24377A_3646 Escherichia coli E24377A hypothetical protein YP_001464637.1 3645304 D 331111 CDS YP_001464638.1 157159443 5590329 complement(3645344..3646228) 1 NC_009801.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 3646228 5590329 EcE24377A_3645 Escherichia coli E24377A lipoprotein NlpI YP_001464638.1 3645344 R 331111 CDS YP_001464639.1 157157852 5585975 3646328..3648496 1 NC_009801.1 identified by glimmer; hypothetical protein 3648496 5585975 EcE24377A_3648 Escherichia coli E24377A hypothetical protein YP_001464639.1 3646328 D 331111 CDS YP_001464640.1 157158403 5588806 complement(3646337..3648472) 1 NC_009801.1 identified by similarity to SP:P05055; match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; polynucleotide phosphorylase 3648472 pnp 5588806 pnp Escherichia coli E24377A polynucleotide phosphorylase YP_001464640.1 3646337 R 331111 CDS YP_001464641.1 157157385 5588702 complement(3648719..3648988) 1 NC_009801.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 3648988 rpsO 5588702 rpsO Escherichia coli E24377A 30S ribosomal protein S15 YP_001464641.1 3648719 R 331111 CDS YP_001464642.1 157155475 5589836 complement(3649137..3650081) 1 NC_009801.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 3650081 truB 5589836 truB Escherichia coli E24377A tRNA pseudouridine synthase B YP_001464642.1 3649137 R 331111 CDS YP_001464643.1 157154949 5588504 complement(3650081..3650482) 1 NC_009801.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 3650482 rbfA 5588504 rbfA Escherichia coli E24377A ribosome-binding factor A YP_001464643.1 3650081 R 331111 CDS YP_001464644.1 157158599 5586604 complement(3650646..3653318) 1 NC_009801.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 3653318 infB 5586604 infB Escherichia coli E24377A translation initiation factor IF-2 YP_001464644.1 3650646 R 331111 CDS YP_001464645.1 157157573 5586333 3653175..3654644 1 NC_009801.1 identified by similarity to GB:AAW76474.1; hypothetical protein 3654644 5586333 EcE24377A_3654 Escherichia coli E24377A hypothetical protein YP_001464645.1 3653175 D 331111 CDS YP_001464646.1 157155683 5590606 complement(3653343..3654830) 1 NC_009801.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 3654830 nusA 5590606 nusA Escherichia coli E24377A transcription elongation factor NusA YP_001464646.1 3653343 R 331111 CDS YP_001464647.1 157159426 5590707 complement(3654858..3655310) 1 NC_009801.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 3655310 5590707 EcE24377A_3655 Escherichia coli E24377A hypothetical protein YP_001464647.1 3654858 R 331111 CDS YP_001464648.1 157155966 5590278 3655941..3657284 1 NC_009801.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3657284 argG 5590278 argG Escherichia coli E24377A argininosuccinate synthase YP_001464648.1 3655941 D 331111 CDS YP_001464649.1 157157677 5586228 complement(3657292..3658917) 1 NC_009801.1 identified by match to protein family HMM PF00884; hypothetical protein 3658917 yhbX 5586228 yhbX Escherichia coli E24377A hypothetical protein YP_001464649.1 3657292 R 331111 CDS YP_001464650.1 157155933 5588607 complement(3659477..3659809) 1 NC_009801.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810; preprotein translocase subunit SecG 3659809 secG 5588607 secG Escherichia coli E24377A preprotein translocase subunit SecG YP_001464650.1 3659477 R 331111 CDS YP_001464651.1 157155381 5586733 complement(3660037..3661374) 1 NC_009801.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 3661374 glmM 5586733 glmM Escherichia coli E24377A phosphoglucosamine mutase YP_001464651.1 3660037 R 331111 CDS YP_001464652.1 157159241 5587565 complement(3661367..3662215) 1 NC_009801.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase 3662215 folP 5587565 folP Escherichia coli E24377A dihydropteroate synthase YP_001464652.1 3661367 R 331111 CDS YP_001464653.1 157158704 5589725 complement(3662305..3664248) 1 NC_009801.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease 3664248 hflB 5589725 hflB Escherichia coli E24377A ATP-dependent metalloprotease YP_001464653.1 3662305 R 331111 CDS YP_001464654.1 157158192 5589226 complement(3664339..3664968) 1 NC_009801.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase 3664968 rrmJ 5589226 rrmJ Escherichia coli E24377A 23S rRNA methyltransferase YP_001464654.1 3664339 R 331111 CDS YP_001464655.1 157157644 5590600 3665094..3665387 1 NC_009801.1 RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3665387 5590600 EcE24377A_3665 Escherichia coli E24377A RNA-binding protein YhbY YP_001464655.1 3665094 D 331111 CDS YP_001464656.1 157156605 5588115 complement(3665543..3666019) 1 NC_009801.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 3666019 greA 5588115 greA Escherichia coli E24377A transcription elongation factor GreA YP_001464656.1 3665543 R 331111 CDS YP_001464657.1 157156989 5586556 3666267..3667700 1 NC_009801.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 3667700 dacB 5586556 dacB Escherichia coli E24377A D-alanyl-D-alanine carboxypeptidase YP_001464657.1 3666267 D 331111 CDS YP_001464658.1 157155525 5590574 complement(3667740..3668912) 1 NC_009801.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 3668912 obgE 5590574 obgE Escherichia coli E24377A GTPase ObgE YP_001464658.1 3667740 R 331111 CDS YP_001464659.1 157157359 5590758 complement(3668928..3669893) 1 NC_009801.1 identified by match to protein family HMM PF00892; transporter 3669893 5590758 EcE24377A_3669 Escherichia coli E24377A transporter YP_001464659.1 3668928 R 331111 CDS YP_001464660.1 157157764 5587906 complement(3670020..3670277) 1 NC_009801.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 3670277 rpmA 5587906 rpmA Escherichia coli E24377A 50S ribosomal protein L27 YP_001464660.1 3670020 R 331111 CDS YP_001464661.1 157159423 5589273 3670271..3670816 1 NC_009801.1 identified by similarity to GB:AAN82384.1; hypothetical protein 3670816 5589273 EcE24377A_3672 Escherichia coli E24377A hypothetical protein YP_001464661.1 3670271 D 331111 CDS YP_001464662.1 157158786 5586132 complement(3670298..3670609) 1 NC_009801.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 3670609 rplU 5586132 rplU Escherichia coli E24377A 50S ribosomal protein L21 YP_001464662.1 3670298 R 331111 CDS YP_001464663.1 157155105 5587870 3670868..3671839 1 NC_009801.1 identified by similarity to SP:P0AD57; match to protein family HMM PF00348; octaprenyl diphosphate synthase 3671839 ispB 5587870 ispB Escherichia coli E24377A octaprenyl diphosphate synthase YP_001464663.1 3670868 D 331111 CDS YP_001464664.1 157155714 5588177 3672066..3672344 1 NC_009801.1 activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3672344 sfsB 5588177 sfsB Escherichia coli E24377A DNA-binding transcriptional regulator Nlp YP_001464664.1 3672066 D 331111 CDS YP_001464665.1 157155579 5588590 complement(3672392..3673651) 1 NC_009801.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3673651 murA 5588590 murA Escherichia coli E24377A UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001464665.1 3672392 R 331111 CDS YP_001464666.1 157155993 5586770 complement(3673706..3673975) 1 NC_009801.1 identified by match to protein family HMM PF01722; BolA/YrbA family protein 3673975 5586770 EcE24377A_3676 Escherichia coli E24377A BolA/YrbA family protein YP_001464666.1 3673706 R 331111 CDS YP_001464667.1 157156647 5587869 3673772..3674113 1 NC_009801.1 identified by similarity to GB:AAN82389.1; hypothetical protein 3674113 5587869 EcE24377A_3677 Escherichia coli E24377A hypothetical protein YP_001464667.1 3673772 D 331111 CDS YP_001464668.1 157157685 5589135 complement(3674120..3674413) 1 NC_009801.1 hypothetical protein 3674413 yrbB 5589135 yrbB Escherichia coli E24377A hypothetical protein YP_001464668.1 3674120 R 331111 CDS YP_001464669.1 157155371 5587963 3674401..3675036 1 NC_009801.1 identified by similarity to GB:AAN82391.1; hypothetical protein 3675036 5587963 EcE24377A_3680 Escherichia coli E24377A hypothetical protein YP_001464669.1 3674401 D 331111 CDS YP_001464670.1 157154788 5587107 complement(3674413..3675048) 1 NC_009801.1 identified by match to protein family HMM PF05494; toluene tolerance protein Ttg2D 3675048 ttg2D 5587107 ttg2D Escherichia coli E24377A toluene tolerance protein Ttg2D YP_001464670.1 3674413 R 331111 CDS YP_001464671.1 157156204 5588580 complement(3675067..3675618) 1 NC_009801.1 identified by match to protein family HMM PF02470; Mce family protein 3675618 5588580 EcE24377A_3681 Escherichia coli E24377A Mce family protein YP_001464671.1 3675067 R 331111 CDS YP_001464672.1 157156689 5587413 complement(3675623..3676405) 1 NC_009801.1 identified by match to protein family HMM PF02405; match to protein family HMM TIGR00056; toluene ABC transporter permease 3676405 5587413 EcE24377A_3682 Escherichia coli E24377A toluene ABC transporter permease YP_001464672.1 3675623 R 331111 CDS YP_001464673.1 157157540 5590335 complement(3676413..3677222) 1 NC_009801.1 ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein 3677222 5590335 EcE24377A_3683 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001464673.1 3676413 R 331111 CDS YP_001464674.1 157158033 5588179 3677432..3678409 1 NC_009801.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 3678409 5588179 EcE24377A_3684 Escherichia coli E24377A calcium/sodium:proton antiporter YP_001464674.1 3677432 D 331111 CDS YP_001464675.1 157158811 5587199 3678423..3679409 1 NC_009801.1 identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; D-arabinose 5-phosphate isomerase 3679409 kdsD 5587199 kdsD Escherichia coli E24377A D-arabinose 5-phosphate isomerase YP_001464675.1 3678423 D 331111 CDS YP_001464676.1 157159366 5590532 3679430..3679996 1 NC_009801.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3679996 kdsC 5590532 kdsC Escherichia coli E24377A 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_001464676.1 3679430 D 331111 CDS YP_001464677.1 157155458 5590079 3679993..3680568 1 NC_009801.1 identified by match to protein family HMM PF06835; hypothetical protein 3680568 5590079 EcE24377A_3687 Escherichia coli E24377A hypothetical protein YP_001464677.1 3679993 D 331111 CDS YP_001464678.1 157156158 5590741 3680537..3681094 1 NC_009801.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3681094 lptA 5590741 lptA Escherichia coli E24377A lipopolysaccharide transport periplasmic protein LptA YP_001464678.1 3680537 D 331111 CDS YP_001464679.1 157158469 5590197 3681101..3681826 1 NC_009801.1 identified by similarity to SP:P0A9V1; match to protein family HMM PF00005; ABC transporter ATP-binding protein 3681826 lptB 5590197 lptB Escherichia coli E24377A ABC transporter ATP-binding protein YP_001464679.1 3681101 D 331111 CDS YP_001464680.1 157158873 5588468 3681874..3683307 1 NC_009801.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3683307 rpoN 5588468 rpoN Escherichia coli E24377A RNA polymerase factor sigma-54 YP_001464680.1 3681874 D 331111 CDS YP_001464681.1 157159184 5586865 3683330..3683617 1 NC_009801.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 3683617 yfiA 5586865 yfiA Escherichia coli E24377A sigma(54) modulation protein YP_001464681.1 3683330 D 331111 CDS YP_001464682.1 157155389 5587763 3683735..3684226 1 NC_009801.1 identified by similarity to SP:P69829; match to protein family HMM PF00359; match to protein family HMM TIGR01419; PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3684226 ptsN 5587763 ptsN Escherichia coli E24377A PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_001464682.1 3683735 D 331111 CDS YP_001464683.1 157156385 5587374 3684272..3685126 1 NC_009801.1 identified by match to protein family HMM PF03668; hypothetical protein 3685126 5587374 EcE24377A_3693 Escherichia coli E24377A hypothetical protein YP_001464683.1 3684272 D 331111 CDS YP_001464684.1 157156736 5587420 3685123..3685395 1 NC_009801.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003; phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3685395 ptsO 5587420 ptsO Escherichia coli E24377A phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) YP_001464684.1 3685123 D 331111 CDS YP_001464685.1 157157272 5586686 3685609..3686241 1 NC_009801.1 identified by similarity to SP:P64611; hypothetical protein 3686241 5586686 EcE24377A_3696 Escherichia coli E24377A hypothetical protein YP_001464685.1 3685609 D 331111 CDS YP_001464686.1 157158590 5588817 complement(3686238..3686966) 1 NC_009801.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 3686966 mtgA 5588817 mtgA Escherichia coli E24377A monofunctional biosynthetic peptidoglycan transglycosylase YP_001464686.1 3686238 R 331111 CDS YP_001464687.1 157159096 5590720 complement(3686963..3687616) 1 NC_009801.1 identified by similarity to SP:P0ABU5; match to protein family HMM PF01965; isoprenoid biosynthesis protein with amidotransferase-like domain 3687616 elbB 5590720 elbB Escherichia coli E24377A isoprenoid biosynthesis protein with amidotransferase-like domain YP_001464687.1 3686963 R 331111 CDS YP_001464688.1 157159325 5588205 complement(3687846..3690182) 1 NC_009801.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB 3690182 arcB 5588205 arcB Escherichia coli E24377A aerobic respiration control sensor protein ArcB YP_001464688.1 3687846 R 331111 CDS YP_001464689.1 157156653 5588492 complement(3690278..3691207) 1 NC_009801.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR01212; radical SAM family protein 3691207 5588492 EcE24377A_3699 Escherichia coli E24377A radical SAM family protein YP_001464689.1 3690278 R 331111 CDS YP_001464690.1 157158022 5589389 3691882..3696342 1 NC_009801.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3696342 gltB 5589389 gltB Escherichia coli E24377A glutamate synthase subunit alpha YP_001464690.1 3691882 D 331111 CDS YP_001464691.1 157158812 5586735 3696355..3697773 1 NC_009801.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3697773 gltD 5586735 gltD Escherichia coli E24377A glutamate synthase subunit beta YP_001464691.1 3696355 D 331111 CDS YP_001464692.1 157159171 5590533 3697957..3699084 1 NC_009801.1 identified by similarity to GB:ABB63386.1; match to protein family HMM PF06250; hypothetical protein 3699084 5590533 EcE24377A_3702 Escherichia coli E24377A hypothetical protein YP_001464692.1 3697957 D 331111 CDS YP_001464693.1 157155045 5587468 complement(3699144..3699608) 1 NC_009801.1 identified by similarity to SP:P0AF97; match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 3699608 5587468 EcE24377A_3703 Escherichia coli E24377A hypothetical protein YP_001464693.1 3699144 R 331111 CDS YP_001464694.1 157155309 5589266 complement(3699605..3700480) 1 NC_009801.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 3700480 5589266 EcE24377A_3704 Escherichia coli E24377A N-acetylmannosamine kinase YP_001464694.1 3699605 R 331111 CDS YP_001464695.1 157156142 5585959 complement(3700477..3701166) 1 NC_009801.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 3701166 5585959 EcE24377A_3705 Escherichia coli E24377A N-acetylmannosamine-6-phosphate 2-epimerase YP_001464695.1 3700477 R 331111 CDS YP_001464696.1 157157675 5589112 complement(3701214..3702704) 1 NC_009801.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00891; sialic acid transporter 3702704 nanT1 5589112 nanT1 Escherichia coli E24377A sialic acid transporter YP_001464696.1 3701214 R 331111 CDS YP_001464697.1 157158110 5588958 complement(3702813..3703706) 1 NC_009801.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 3703706 nanA 5588958 nanA Escherichia coli E24377A N-acetylneuraminate lyase YP_001464697.1 3702813 R 331111 CDS YP_001464698.1 157157774 5586067 complement(3703828..3704610) 1 NC_009801.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR 3704610 nanR 5586067 nanR Escherichia coli E24377A transcriptional regulator NanR YP_001464698.1 3703828 R 331111 CDS YP_001464699.1 157155112 5588536 3704999..3706321 1 NC_009801.1 YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic; cryptic C4-dicarboxylate transporter DcuD 3706321 5588536 EcE24377A_3709 Escherichia coli E24377A cryptic C4-dicarboxylate transporter DcuD YP_001464699.1 3704999 D 331111 CDS YP_001464700.1 157156406 5587844 3706296..3706430 1 NC_009801.1 identified by glimmer; hypothetical protein 3706430 5587844 EcE24377A_3711 Escherichia coli E24377A hypothetical protein YP_001464700.1 3706296 D 331111 CDS YP_001464701.1 157157016 5587725 complement(3706364..3706861) 1 NC_009801.1 identified by match to protein family HMM PF04386; ClpXP protease specificity-enhancing factor 3706861 sspB 5587725 sspB Escherichia coli E24377A ClpXP protease specificity-enhancing factor YP_001464701.1 3706364 R 331111 CDS YP_001464702.1 157158762 5586189 complement(3706867..3707505) 1 NC_009801.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 3707505 sspA 5586189 sspA Escherichia coli E24377A stringent starvation protein A YP_001464702.1 3706867 R 331111 CDS YP_001464703.1 157157775 5590801 complement(3707900..3708292) 1 NC_009801.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3708292 rpsI 5590801 rpsI Escherichia coli E24377A 30S ribosomal protein S9 YP_001464703.1 3707900 R 331111 CDS YP_001464704.1 157154937 5586677 complement(3708308..3708736) 1 NC_009801.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3708736 rplM 5586677 rplM Escherichia coli E24377A 50S ribosomal protein L13 YP_001464704.1 3708308 R 331111 CDS YP_001464705.1 157159011 5587302 complement(3708955..3710082) 1 NC_009801.1 identified by match to protein family HMM PF03969; AFG1 family ATPase 3710082 5587302 EcE24377A_3715 Escherichia coli E24377A AFG1 family ATPase YP_001464705.1 3708955 R 331111 CDS YP_001464706.1 157156704 5588944 3710276..3710674 1 NC_009801.1 identified by match to protein family HMM PF06295; cytochrome d ubiquinol oxidase subunit III 3710674 5588944 EcE24377A_3716 Escherichia coli E24377A cytochrome d ubiquinol oxidase subunit III YP_001464706.1 3710276 D 331111 CDS YP_001464707.1 157156170 5588791 3710828..3712195 1 NC_009801.1 identified by similarity to SP:P39099; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; serine endoprotease 3712195 degQ 5588791 degQ Escherichia coli E24377A serine endoprotease YP_001464707.1 3710828 D 331111 CDS YP_001464708.1 157157456 5590786 3712285..3713352 1 NC_009801.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02038; serine endoprotease 3713352 degS 5590786 degS Escherichia coli E24377A serine endoprotease YP_001464708.1 3712285 D 331111 CDS YP_001464709.1 157155698 5586293 complement(3713414..3714352) 1 NC_009801.1 oxidizes malate to oxaloacetate; malate dehydrogenase 3714352 mdh 5586293 mdh Escherichia coli E24377A malate dehydrogenase YP_001464709.1 3713414 R 331111 CDS YP_001464710.1 157158570 5587916 3714787..3715257 1 NC_009801.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 3715257 argR 5587916 argR Escherichia coli E24377A arginine repressor ArgR YP_001464710.1 3714787 D 331111 CDS YP_001464711.1 157159141 5588722 3715622..3715885 1 NC_009801.1 identified by similarity to SP:P0AB40; match to protein family HMM PF07338; protein YcfR 3715885 ycfR 5588722 ycfR Escherichia coli E24377A protein YcfR YP_001464711.1 3715622 D 331111 CDS YP_001464712.1 157156620 5589284 complement(3715941..3716213) 1 NC_009801.1 identified by similarity to SP:P64616; hypothetical protein 3716213 5589284 EcE24377A_3722 Escherichia coli E24377A hypothetical protein YP_001464712.1 3715941 R 331111 CDS YP_001464713.1 157156987 5590071 complement(3716305..3718272) 1 NC_009801.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB 3718272 aaeB 5590071 aaeB Escherichia coli E24377A p-hydroxybenzoic acid efflux subunit AaeB YP_001464713.1 3716305 R 331111 CDS YP_001464714.1 157155237 5590696 complement(3718278..3719210) 1 NC_009801.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA 3719210 aaeA 5590696 aaeA Escherichia coli E24377A p-hydroxybenzoic acid efflux subunit AaeA YP_001464714.1 3718278 R 331111 CDS YP_001464715.2 229220662 5590134 complement(3719218..3719421) 1 NC_009801.1 membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein 3719421 aaeX 5590134 aaeX Escherichia coli E24377A hypothetical protein YP_001464715.2 3719218 R 331111 CDS YP_001464716.1 157158690 5589083 3719604..3720533 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator 3720533 aaeR 5589083 aaeR Escherichia coli E24377A DNA-binding transcriptional regulator YP_001464716.1 3719604 D 331111 CDS YP_001464717.1 157159207 5590416 complement(3720661..3722106) 1 NC_009801.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD 3722106 tldD 5590416 tldD Escherichia coli E24377A protease TldD YP_001464717.1 3720661 R 331111 CDS YP_001464718.1 157157619 5586624 complement(3722262..3726062) 1 NC_009801.1 identified by match to protein family HMM TIGR02099; hypothetical protein 3726062 5586624 EcE24377A_3728 Escherichia coli E24377A hypothetical protein YP_001464718.1 3722262 R 331111 CDS YP_001464719.1 157159301 5590130 complement(3726130..3727599) 1 NC_009801.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 3727599 cafA 5590130 cafA Escherichia coli E24377A ribonuclease G YP_001464719.1 3726130 R 331111 CDS YP_001464720.1 157158373 5590485 complement(3727589..3728182) 1 NC_009801.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 3728182 maf1 5590485 maf1 Escherichia coli E24377A Maf-like protein YP_001464720.1 3727589 R 331111 CDS YP_001464721.1 157155778 5586082 complement(3728191..3728679) 1 NC_009801.1 part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 3728679 lytS 5586082 lytS Escherichia coli E24377A rod shape-determining protein MreD YP_001464721.1 3728191 R 331111 CDS YP_001464723.1 157156676 5588666 complement(3728679..3729782) 1 NC_009801.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 3729782 mreC 5588666 mreC Escherichia coli E24377A rod shape-determining protein MreC YP_001464723.1 3728679 R 331111 CDS YP_001464724.1 157158081 5587386 complement(3729848..3730891) 1 NC_009801.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 3730891 mreB 5587386 mreB Escherichia coli E24377A rod shape-determining protein MreB YP_001464724.1 3729848 R 331111 CDS YP_001464725.1 157157440 5590136 3730999..3731187 1 NC_009801.1 identified by similarity to GB:AAN82447.1; hypothetical protein 3731187 5590136 EcE24377A_3735 Escherichia coli E24377A hypothetical protein YP_001464725.1 3730999 D 331111 CDS YP_001464726.1 157159387 5587363 complement(3731196..3733136) 1 NC_009801.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 3733136 5587363 EcE24377A_3736 Escherichia coli E24377A regulatory protein CsrD YP_001464726.1 3731196 R 331111 CDS YP_001464727.1 157158862 5586257 3733288..3734262 1 NC_009801.1 identified by similarity to PDB:1O8C_A; match to protein family HMM PF00107; match to protein family HMM PF01262; match to protein family HMM PF08240; match to protein family HMM TIGR02823; quinone oxidoreductase 3734262 5586257 EcE24377A_3737 Escherichia coli E24377A quinone oxidoreductase YP_001464727.1 3733288 D 331111 CDS YP_001464728.1 157158042 5589829 3735240..3735710 1 NC_009801.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3735710 accB 5589829 accB Escherichia coli E24377A acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_001464728.1 3735240 D 331111 CDS YP_001464729.1 157157399 5589131 3735721..3737070 1 NC_009801.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3737070 accC 5589131 accC Escherichia coli E24377A acetyl-CoA carboxylase biotin carboxylase subunit YP_001464729.1 3735721 D 331111 CDS YP_001464730.1 157159070 5589510 3737179..3737421 1 NC_009801.1 identified by match to protein family HMM PF06196; hypothetical protein 3737421 5589510 EcE24377A_3741 Escherichia coli E24377A hypothetical protein YP_001464730.1 3737179 D 331111 CDS YP_001464731.1 157155341 5588422 3737411..3738862 1 NC_009801.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3738862 panF 5588422 panF Escherichia coli E24377A sodium/panthothenate symporter YP_001464731.1 3737411 D 331111 CDS YP_001464732.1 157155833 5589299 3738874..3739755 1 NC_009801.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 3739755 prmA 5589299 prmA Escherichia coli E24377A 50S ribosomal protein L11 methyltransferase YP_001464732.1 3738874 D 331111 CDS YP_001464733.1 157156693 5588412 3739820..3739912 1 NC_009801.1 identified by glimmer; hypothetical protein 3739912 5588412 EcE24377A_3744 Escherichia coli E24377A hypothetical protein YP_001464733.1 3739820 D 331111 CDS YP_001464734.1 157156175 5587941 3740084..3741049 1 NC_009801.1 identified by similarity to SP:P0ABT5; match to protein family HMM PF01207; match to protein family HMM TIGR00737; tRNA-dihydrouridine synthase B 3741049 dusB 5587941 dusB Escherichia coli E24377A tRNA-dihydrouridine synthase B YP_001464734.1 3740084 D 331111 CDS YP_001464735.1 157158082 5589740 3741075..3741371 1 NC_009801.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3741371 fis 5589740 fis Escherichia coli E24377A DNA-binding protein Fis YP_001464735.1 3741075 D 331111 CDS YP_001464736.1 157157471 5590137 3741457..3742341 1 NC_009801.1 identified by match to protein family HMM PF01555; methyltransferase 3742341 5590137 EcE24377A_3747 Escherichia coli E24377A methyltransferase YP_001464736.1 3741457 D 331111 CDS YP_001464737.1 157159436 5589646 3742398..3742604 1 NC_009801.1 identified by similarity to GB:AAN82469.1; hypothetical protein 3742604 5589646 EcE24377A_3748 Escherichia coli E24377A hypothetical protein YP_001464737.1 3742398 D 331111 CDS YP_001464738.1 157158036 5587618 complement(3742607..3743269) 1 NC_009801.1 identified by similarity to SP:P0ACT2; match to protein family HMM PF00440; match to protein family HMM PF08361; DNA-binding transcriptional regulator EnvR 3743269 5587618 EcE24377A_3749 Escherichia coli E24377A DNA-binding transcriptional regulator EnvR YP_001464738.1 3742607 R 331111 CDS YP_001464739.1 157155709 5587573 3743668..3744825 1 NC_009801.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; acriflavine resistance protein E 3744825 acrE 5587573 acrE Escherichia coli E24377A acriflavine resistance protein E YP_001464739.1 3743668 D 331111 CDS YP_001464740.1 157155020 5588989 3744837..3747941 1 NC_009801.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; acriflavine resistance protein F 3747941 acrF 5588989 acrF Escherichia coli E24377A acriflavine resistance protein F YP_001464740.1 3744837 D 331111 CDS YP_001464741.1 157158583 5587130 3748194..3748415 1 NC_009801.1 lipoprotein 3748415 5587130 EcE24377A_3752 Escherichia coli E24377A lipoprotein YP_001464741.1 3748194 D 331111 CDS YP_001464742.1 157155506 5588620 3748641..3748817 1 NC_009801.1 hypothetical protein 3748817 5588620 EcE24377A_3753 Escherichia coli E24377A hypothetical protein YP_001464742.1 3748641 D 331111 CDS YP_001464743.1 157159268 5590153 3748846..3749871 1 NC_009801.1 amino acid ABC transporter substrate-binding protein 3749871 5590153 EcE24377A_3754 Escherichia coli E24377A amino acid ABC transporter substrate-binding protein YP_001464743.1 3748846 D 331111 CDS YP_001464744.1 157158458 5588381 3749939..3751120 1 NC_009801.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; His/Glu/Gln/Arg/opine ABC transporter permease 3751120 5588381 EcE24377A_3755 Escherichia coli E24377A His/Glu/Gln/Arg/opine ABC transporter permease YP_001464744.1 3749939 D 331111 CDS YP_001464745.1 157158180 5587123 3751130..3752233 1 NC_009801.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; His/Glu/Gln/Arg/opine ABC transporter permease 3752233 5587123 EcE24377A_3756 Escherichia coli E24377A His/Glu/Gln/Arg/opine ABC transporter permease YP_001464745.1 3751130 D 331111 CDS YP_001464746.1 157157435 5586523 3752241..3752999 1 NC_009801.1 yhdZ; identified by match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 3752999 5586523 EcE24377A_3757 Escherichia coli E24377A amino acid ABC transporter ATP-binding protein YP_001464746.1 3752241 D 331111 CDS YP_001464747.1 157159463 5586203 3758722..3759603 1 NC_009801.1 hypothetical protein 3759603 5586203 EcE24377A_3763 Escherichia coli E24377A hypothetical protein YP_001464747.1 3758722 D 331111 CDS YP_001464748.1 157156190 5587120 complement(3759579..3759836) 1 NC_009801.1 identified by similarity to SP:P45795; match to protein family HMM PF07369; hypothetical protein 3759836 5587120 EcE24377A_3762 Escherichia coli E24377A hypothetical protein YP_001464748.1 3759579 R 331111 CDS YP_001464749.1 157157510 5588912 complement(3759833..3760651) 1 NC_009801.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 3760651 aroE 5588912 aroE Escherichia coli E24377A shikimate 5-dehydrogenase YP_001464749.1 3759833 R 331111 CDS YP_001464750.1 157154846 5586472 complement(3760656..3761273) 1 NC_009801.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor 3761273 5586472 EcE24377A_3765 Escherichia coli E24377A ribosome maturation factor YP_001464750.1 3760656 R 331111 CDS YP_001464751.1 157155337 5590612 complement(3761233..3761775) 1 NC_009801.1 identified by match to protein family HMM PF01396; topoisomerase DNA-binding C4 zinc finger domain-containing protein 3761775 5590612 EcE24377A_3766 Escherichia coli E24377A topoisomerase DNA-binding C4 zinc finger domain-containing protein YP_001464751.1 3761233 R 331111 CDS YP_001464752.1 157156173 5590032 complement(3761804..3762277) 1 NC_009801.1 identified by similarity to SP:P66822; match to protein family HMM PF04361; hypothetical protein 3762277 smg 5590032 smg Escherichia coli E24377A hypothetical protein YP_001464752.1 3761804 R 331111 CDS YP_001464753.1 157156735 5589820 complement(3762249..3763373) 1 NC_009801.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732; DNA protecting protein DprA 3763373 dprA 5589820 dprA Escherichia coli E24377A DNA protecting protein DprA YP_001464753.1 3762249 R 331111 CDS YP_001464754.1 157156138 5586685 3763503..3764012 1 NC_009801.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3764012 def 5586685 def Escherichia coli E24377A peptide deformylase YP_001464754.1 3763503 D 331111 CDS YP_001464755.1 157156687 5587402 3764027..3764974 1 NC_009801.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3764974 fmt 5587402 fmt Escherichia coli E24377A methionyl-tRNA formyltransferase YP_001464755.1 3764027 D 331111 CDS YP_001464756.1 157157639 5587411 3765020..3766309 1 NC_009801.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase GidB 3766309 rsmB 5587411 rsmB Escherichia coli E24377A 16S rRNA methyltransferase GidB YP_001464756.1 3765020 D 331111 CDS YP_001464757.1 157159217 5589802 3766331..3767707 1 NC_009801.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 3767707 trkA 5589802 trkA Escherichia coli E24377A potassium transporter peripheral membrane protein YP_001464757.1 3766331 D 331111 CDS YP_001464758.1 157154868 5586513 3767837..3768247 1 NC_009801.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3768247 mscL 5586513 mscL Escherichia coli E24377A large-conductance mechanosensitive channel YP_001464758.1 3767837 D 331111 CDS YP_001464759.1 157156652 5589160 complement(3768244..3768462) 1 NC_009801.1 identified by match to protein family HMM PF03889; hypothetical protein 3768462 5589160 EcE24377A_3773 Escherichia coli E24377A hypothetical protein YP_001464759.1 3768244 R 331111 CDS YP_001464760.1 157159430 5589388 complement(3768518..3768943) 1 NC_009801.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 3768943 zntR 5589388 zntR Escherichia coli E24377A zinc-responsive transcriptional regulator YP_001464760.1 3768518 R 331111 CDS YP_001464761.1 157158769 5590364 complement(3768954..3769322) 1 NC_009801.1 identified by similarity to SP:P36677; hypothetical protein 3769322 5590364 EcE24377A_3776 Escherichia coli E24377A hypothetical protein YP_001464761.1 3768954 R 331111 CDS YP_001464762.1 157158062 5587888 complement(3769429..3769812) 1 NC_009801.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 3769812 rplQ 5587888 rplQ Escherichia coli E24377A 50S ribosomal protein L17 YP_001464762.1 3769429 R 331111 CDS YP_001464763.1 157157450 5586179 complement(3769853..3770842) 1 NC_009801.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 3770842 rpoA 5586179 rpoA Escherichia coli E24377A DNA-directed RNA polymerase subunit alpha YP_001464763.1 3769853 R 331111 CDS YP_001464764.1 157156792 5590248 complement(3770868..3771488) 1 NC_009801.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3771488 rpsD 5590248 rpsD Escherichia coli E24377A 30S ribosomal protein S4 YP_001464764.1 3770868 R 331111 CDS YP_001464765.1 157156126 5588562 complement(3771522..3771911) 1 NC_009801.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 3771911 rpsK 5588562 rpsK Escherichia coli E24377A 30S ribosomal protein S11 YP_001464765.1 3771522 R 331111 CDS YP_001464766.1 157156782 5586542 complement(3771928..3772284) 1 NC_009801.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 3772284 rpsM 5586542 rpsM Escherichia coli E24377A 30S ribosomal protein S13 YP_001464766.1 3771928 R 331111 CDS YP_001464767.1 157155446 5588641 complement(3772431..3772547) 1 NC_009801.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 3772547 rpmJ 5588641 rpmJ Escherichia coli E24377A 50S ribosomal protein L36 YP_001464767.1 3772431 R 331111 CDS YP_001464768.1 157158750 5589888 complement(3772579..3773910) 1 NC_009801.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 3773910 secY 5589888 secY Escherichia coli E24377A preprotein translocase subunit SecY YP_001464768.1 3772579 R 331111 CDS YP_001464769.1 157157035 5586352 complement(3773918..3774352) 1 NC_009801.1 late assembly protein; 50S ribosomal protein L15 3774352 rplO 5586352 rplO Escherichia coli E24377A 50S ribosomal protein L15 YP_001464769.1 3773918 R 331111 CDS YP_001464770.1 157156512 5587641 complement(3774356..3774535) 1 NC_009801.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 3774535 rpmD 5587641 rpmD Escherichia coli E24377A 50S ribosomal protein L30 YP_001464770.1 3774356 R 331111 CDS YP_001464771.1 157155673 5588065 complement(3774539..3775042) 1 NC_009801.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 3775042 rpsE 5588065 rpsE Escherichia coli E24377A 30S ribosomal protein S5 YP_001464771.1 3774539 R 331111 CDS YP_001464772.1 157158906 5587030 complement(3775057..3775410) 1 NC_009801.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 3775410 rplR 5587030 rplR Escherichia coli E24377A 50S ribosomal protein L18 YP_001464772.1 3775057 R 331111 CDS YP_001464773.1 157158568 5587035 complement(3775420..3775953) 1 NC_009801.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 3775953 rplF 5587035 rplF Escherichia coli E24377A 50S ribosomal protein L6 YP_001464773.1 3775420 R 331111 CDS YP_001464774.1 157157108 5588720 complement(3775966..3776358) 1 NC_009801.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 3776358 rpsH 5588720 rpsH Escherichia coli E24377A 30S ribosomal protein S8 YP_001464774.1 3775966 R 331111 CDS YP_001464775.1 157158065 5587112 complement(3776392..3776697) 1 NC_009801.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 3776697 rpsN 5587112 rpsN Escherichia coli E24377A 30S ribosomal protein S14 YP_001464775.1 3776392 R 331111 CDS YP_001464776.1 157158313 5586898 complement(3776712..3777251) 1 NC_009801.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 3777251 rplE 5586898 rplE Escherichia coli E24377A 50S ribosomal protein L5 YP_001464776.1 3776712 R 331111 CDS YP_001464777.1 157159126 5590171 complement(3777266..3777580) 1 NC_009801.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 3777580 rplX 5590171 rplX Escherichia coli E24377A 50S ribosomal protein L24 YP_001464777.1 3777266 R 331111 CDS YP_001464778.1 157155839 5586812 complement(3777591..3777962) 1 NC_009801.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 3777962 rplN 5586812 rplN Escherichia coli E24377A 50S ribosomal protein L14 YP_001464778.1 3777591 R 331111 CDS YP_001464779.1 157156252 5589511 complement(3778127..3778381) 1 NC_009801.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 3778381 rpsQ 5589511 rpsQ Escherichia coli E24377A 30S ribosomal protein S17 YP_001464779.1 3778127 R 331111 CDS YP_001464780.1 157157167 5590221 complement(3778381..3778572) 1 NC_009801.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 3778572 rpmC 5590221 rpmC Escherichia coli E24377A 50S ribosomal protein L29 YP_001464780.1 3778381 R 331111 CDS YP_001464781.1 157157561 5588276 complement(3778572..3778982) 1 NC_009801.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 3778982 rplP 5588276 rplP Escherichia coli E24377A 50S ribosomal protein L16 YP_001464781.1 3778572 R 331111 CDS YP_001464782.1 157157923 5589386 complement(3778995..3779696) 1 NC_009801.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 3779696 rpsC 5589386 rpsC Escherichia coli E24377A 30S ribosomal protein S3 YP_001464782.1 3778995 R 331111 CDS YP_001464783.1 157155565 5586986 complement(3779714..3780046) 1 NC_009801.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 3780046 rplV 5586986 rplV Escherichia coli E24377A 50S ribosomal protein L22 YP_001464783.1 3779714 R 331111 CDS YP_001464784.1 157159404 5585936 complement(3780061..3780339) 1 NC_009801.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 3780339 rpsS 5585936 rpsS Escherichia coli E24377A 30S ribosomal protein S19 YP_001464784.1 3780061 R 331111 CDS YP_001464785.1 157157488 5589908 complement(3780356..3781177) 1 NC_009801.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 3781177 rplB 5589908 rplB Escherichia coli E24377A 50S ribosomal protein L2 YP_001464785.1 3780356 R 331111 CDS YP_001464786.1 157157666 5589037 complement(3781195..3781497) 1 NC_009801.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 3781497 rplW 5589037 rplW Escherichia coli E24377A 50S ribosomal protein L23 YP_001464786.1 3781195 R 331111 CDS YP_001464787.1 157156089 5588810 complement(3781494..3782099) 1 NC_009801.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 3782099 rplD 5588810 rplD Escherichia coli E24377A 50S ribosomal protein L4 YP_001464787.1 3781494 R 331111 CDS YP_001464788.1 157156606 5590558 complement(3782110..3782739) 1 NC_009801.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 3782739 rplC 5590558 rplC Escherichia coli E24377A 50S ribosomal protein L3 YP_001464788.1 3782110 R 331111 CDS YP_001464789.1 157159214 5586557 complement(3782772..3783083) 1 NC_009801.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 3783083 rpsJ 5586557 rpsJ Escherichia coli E24377A 30S ribosomal protein S10 YP_001464789.1 3782772 R 331111 CDS YP_001464790.1 157157487 5587464 3783462..3783929 1 NC_009801.1 identified by match to protein family HMM PF01478; A24 family peptidase 3783929 5587464 EcE24377A_3806 Escherichia coli E24377A A24 family peptidase YP_001464790.1 3783462 D 331111 CDS YP_001464791.1 157158591 5588378 complement(3783926..3784402) 1 NC_009801.1 iron storage protein; bacterioferritin 3784402 bfr 5588378 bfr Escherichia coli E24377A bacterioferritin YP_001464791.1 3783926 R 331111 CDS YP_001464792.1 157155378 5586464 complement(3784475..3784669) 1 NC_009801.1 identified by similarity to SP:P0AE56; match to protein family HMM PF04324; bacterioferritin-associated ferredoxin 3784669 bfd 5586464 bfd Escherichia coli E24377A bacterioferritin-associated ferredoxin YP_001464792.1 3784475 R 331111 CDS YP_001464793.1 157154720 5587408 complement(3784852..3786036) 1 NC_009801.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 3786036 tuf1 5587408 tuf1 Escherichia coli E24377A elongation factor Tu YP_001464793.1 3784852 R 331111 CDS YP_001464794.1 157157042 5589684 complement(3786107..3788221) 1 NC_009801.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 3788221 fusA 5589684 fusA Escherichia coli E24377A elongation factor G YP_001464794.1 3786107 R 331111 CDS YP_001464795.1 157157663 5588799 complement(3788318..3788788) 1 NC_009801.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 3788788 rpsG 5588799 rpsG Escherichia coli E24377A 30S ribosomal protein S7 YP_001464795.1 3788318 R 331111 CDS YP_001464796.1 157159216 5590808 complement(3788885..3789259) 1 NC_009801.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 3789259 rpsL 5590808 rpsL Escherichia coli E24377A 30S ribosomal protein S12 YP_001464796.1 3788885 R 331111 CDS YP_001464797.1 157159145 5586512 complement(3789385..3789672) 1 NC_009801.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 3789672 dsrH 5586512 dsrH Escherichia coli E24377A sulfur transfer complex subunit TusB YP_001464797.1 3789385 R 331111 CDS YP_001464798.1 157159165 5590744 complement(3789680..3790039) 1 NC_009801.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 3790039 tusC 5590744 tusC Escherichia coli E24377A sulfur relay protein TusC YP_001464798.1 3789680 R 331111 CDS YP_001464799.1 157158490 5588199 complement(3790039..3790425) 1 NC_009801.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 3790425 tusD 5588199 tusD Escherichia coli E24377A sulfur transfer complex subunit TusD YP_001464799.1 3790039 R 331111 CDS YP_001464800.1 157159124 5588003 complement(3790425..3791147) 1 NC_009801.1 identified by match to protein family HMM PF08348; hypothetical protein 3791147 5588003 EcE24377A_3815 Escherichia coli E24377A hypothetical protein YP_001464800.1 3790425 R 331111 CDS YP_001464801.1 157157129 5589120 complement(3791314..3792126) 1 NC_009801.1 rotamase; FKBP-type peptidylprolyl isomerase 3792126 fkpA 5589120 fkpA Escherichia coli E24377A FKBP-type peptidylprolyl isomerase YP_001464801.1 3791314 R 331111 CDS YP_001464802.1 157156408 5585990 3792347..3792565 1 NC_009801.1 identified by match to protein family HMM PF04102; hypothetical protein 3792565 5585990 EcE24377A_3817 Escherichia coli E24377A hypothetical protein YP_001464802.1 3792347 D 331111 CDS YP_001464803.1 157156053 5586703 complement(3792614..3793204) 1 NC_009801.1 rotamase; FKBP-type peptidylprolyl isomerase 3793204 slyD 5586703 slyD Escherichia coli E24377A FKBP-type peptidylprolyl isomerase YP_001464803.1 3792614 R 331111 CDS YP_001464804.1 157157073 5588221 complement(3793299..3793499) 1 NC_009801.1 identified by similarity to SP:P0ADW8; match to protein family HMM TIGR02443; hypothetical protein 3793499 5588221 EcE24377A_3819 Escherichia coli E24377A hypothetical protein YP_001464804.1 3793299 R 331111 CDS YP_001464805.1 157155180 5589033 complement(3793509..3795314) 1 NC_009801.1 involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB 3795314 kefB 5589033 kefB Escherichia coli E24377A glutathione-regulated potassium-efflux system protein KefB YP_001464805.1 3793509 R 331111 CDS YP_001464806.1 157155512 5588769 complement(3795314..3795868) 1 NC_009801.1 required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 3795868 kefG 5588769 kefG Escherichia coli E24377A glutathione-regulated potassium-efflux system ancillary protein KefG YP_001464806.1 3795314 R 331111 CDS YP_001464807.1 157158724 5587037 3795996..3797909 1 NC_009801.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 3797909 5587037 EcE24377A_3822 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001464807.1 3795996 D 331111 CDS YP_001464808.1 157158481 5586422 3797909..3798931 1 NC_009801.1 identified by match to protein family HMM PF00561; hydrolase 3798931 5586422 EcE24377A_3823 Escherichia coli E24377A hydrolase YP_001464808.1 3797909 D 331111 CDS YP_001464809.1 157159122 5590403 3798925..3799143 1 NC_009801.1 identified by match to protein family HMM PF06794; hypothetical protein 3799143 5590403 EcE24377A_3824 Escherichia coli E24377A hypothetical protein YP_001464809.1 3798925 D 331111 CDS YP_001464810.1 157158464 5589118 3799197..3800066 1 NC_009801.1 identified by match to protein family HMM PF00485; phosphoribulokinase/uridine kinase 3800066 5589118 EcE24377A_3825 Escherichia coli E24377A phosphoribulokinase/uridine kinase YP_001464810.1 3799197 D 331111 CDS YP_001464811.1 157158908 5586669 complement(3800121..3800525) 1 NC_009801.1 identified by match to protein family HMM PF02566; hypothetical protein 3800525 5586669 EcE24377A_3826 Escherichia coli E24377A hypothetical protein YP_001464811.1 3800121 R 331111 CDS YP_001464812.1 157159326 5589337 3800827..3801459 1 NC_009801.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3801459 crp 5589337 crp Escherichia coli E24377A cAMP-regulatory protein YP_001464812.1 3800827 D 331111 CDS YP_001464813.1 157157901 5588493 3801510..3803600 1 NC_009801.1 identified by match to protein family HMM PF05976; match to protein family HMM TIGR01667; hypothetical protein 3803600 5588493 EcE24377A_3828 Escherichia coli E24377A hypothetical protein YP_001464813.1 3801510 D 331111 CDS YP_001464814.1 157158142 5587568 complement(3803667..3804887) 1 NC_009801.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase 3804887 argD 5587568 argD Escherichia coli E24377A bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase YP_001464814.1 3803667 R 331111 CDS YP_001464815.1 157156286 5590828 complement(3804973..3805536) 1 NC_009801.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 3805536 pabA 5590828 pabA Escherichia coli E24377A para-aminobenzoate synthase component II YP_001464815.1 3804973 R 331111 CDS YP_001464816.1 157156535 5589787 complement(3805568..3806170) 1 NC_009801.1 identified by similarity to SP:P20605; match to protein family HMM PF02661; cell filamentation protein Fic 3806170 fic 5589787 fic Escherichia coli E24377A cell filamentation protein Fic YP_001464816.1 3805568 R 331111 CDS YP_001464817.1 157154785 5586975 complement(3806432..3807004) 1 NC_009801.1 identified by similarity to SP:P20752; match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase A 3807004 ppiA 5586975 ppiA Escherichia coli E24377A peptidyl-prolyl cis-trans isomerase A YP_001464817.1 3806432 R 331111 CDS YP_001464818.1 157155575 5588664 3807275..3808456 1 NC_009801.1 identified by match to protein family HMM PF07690; hypothetical protein 3808456 tsgA 5588664 tsgA Escherichia coli E24377A hypothetical protein YP_001464818.1 3807275 D 331111 CDS YP_001464819.1 157158374 5588426 complement(3808589..3808765) 1 NC_009801.1 identified by similarity to GB:AAX67313.1; hypothetical protein 3808765 5588426 EcE24377A_3834 Escherichia coli E24377A hypothetical protein YP_001464819.1 3808589 R 331111 CDS YP_001464820.1 157156533 5586083 3808718..3811261 1 NC_009801.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374; nitrite reductase [NAD(P)H], large subunit 3811261 nirB 5586083 nirB Escherichia coli E24377A nitrite reductase [NAD(P)H], large subunit YP_001464820.1 3808718 D 331111 CDS YP_001464821.1 157156005 5586973 3811258..3811584 1 NC_009801.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3811584 nirD 5586973 nirD Escherichia coli E24377A nitrite reductase small subunit YP_001464821.1 3811258 D 331111 CDS YP_001464822.1 157157586 5586784 3811711..3812517 1 NC_009801.1 member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3812517 nirC 5586784 nirC Escherichia coli E24377A nitrite transporter NirC YP_001464822.1 3811711 D 331111 CDS YP_001464823.1 157157083 5585910 3812536..3813909 1 NC_009801.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3813909 cysG 5585910 cysG Escherichia coli E24377A siroheme synthase YP_001464823.1 3812536 D 331111 CDS YP_001464824.1 157158620 5589524 3814156..3814323 1 NC_009801.1 lipoprotein 3814323 5589524 EcE24377A_3839 Escherichia coli E24377A lipoprotein YP_001464824.1 3814156 D 331111 CDS YP_001464825.1 157157958 5590330 3814567..3815955 1 NC_009801.1 inner membrane protein possibly involved in fructoselysine transport; member of the flr operon; fructoselysine transporter 3815955 frlA 5590330 frlA Escherichia coli E24377A fructoselysine transporter YP_001464825.1 3814567 D 331111 CDS YP_001464826.1 157154946 5586654 3815955..3816998 1 NC_009801.1 catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine; fructoselysine-6-P-deglycase 3816998 frlB 5586654 frlB Escherichia coli E24377A fructoselysine-6-P-deglycase YP_001464826.1 3815955 D 331111 CDS YP_001464827.1 157158886 5590804 3817048..3817878 1 NC_009801.1 YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine; fructoselysine 3-epimerase 3817878 5590804 EcE24377A_3842 Escherichia coli E24377A fructoselysine 3-epimerase YP_001464827.1 3817048 D 331111 CDS YP_001464828.1 157156039 5586845 3817875..3818660 1 NC_009801.1 identified by match to protein family HMM PF00294; fructoselysine 6-kinase 3818660 5586845 EcE24377A_3843 Escherichia coli E24377A fructoselysine 6-kinase YP_001464828.1 3817875 D 331111 CDS YP_001464829.1 157155159 5588332 3818760..3819491 1 NC_009801.1 may act as a transcriptional regulator of a fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes; DNA-binding transcriptional regulator FrlR 3819491 frlR 5588332 frlR Escherichia coli E24377A DNA-binding transcriptional regulator FrlR YP_001464829.1 3818760 D 331111 CDS YP_001464830.1 157155172 5587046 complement(3819643..3820728) 1 NC_009801.1 identified by similarity to GB:ABB67851.1; hypothetical protein 3820728 5587046 EcE24377A_3845 Escherichia coli E24377A hypothetical protein YP_001464830.1 3819643 R 331111 CDS YP_001464831.1 157159380 5587733 complement(3820740..3822044) 1 NC_009801.1 identified by similarity to SP:P45546; hypothetical protein 3822044 5587733 EcE24377A_3846 Escherichia coli E24377A hypothetical protein YP_001464831.1 3820740 R 331111 CDS YP_001464832.1 157158840 5588257 complement(3822056..3822409) 1 NC_009801.1 hypothetical protein 3822409 5588257 EcE24377A_3847 Escherichia coli E24377A hypothetical protein YP_001464832.1 3822056 R 331111 CDS YP_001464833.1 157158103 5590778 complement(3822420..3823298) 1 NC_009801.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); hydrolase 3823298 5590778 EcE24377A_3848 Escherichia coli E24377A hydrolase YP_001464833.1 3822420 R 331111 CDS YP_001464834.1 157156741 5588946 complement(3823295..3824521) 1 NC_009801.1 identified by match to protein family HMM PF01676; match to protein family HMM PF08342; mutase 3824521 5588946 EcE24377A_3849 Escherichia coli E24377A mutase YP_001464834.1 3823295 R 331111 CDS YP_001464835.1 157156148 5587330 complement(3824521..3825684) 1 NC_009801.1 identified by match to protein family HMM PF01168; alanine racemase 3825684 5587330 EcE24377A_3850 Escherichia coli E24377A alanine racemase YP_001464835.1 3824521 R 331111 CDS YP_001464836.1 157155316 5590182 complement(3825768..3826130) 1 NC_009801.1 hypothetical protein 3826130 5590182 EcE24377A_3851 Escherichia coli E24377A hypothetical protein YP_001464836.1 3825768 R 331111 CDS YP_001464837.1 157154799 5590501 complement(3826147..3827052) 1 NC_009801.1 identified by similarity to OMNI:NTL01SF3196; hypothetical protein 3827052 5590501 EcE24377A_3852 Escherichia coli E24377A hypothetical protein YP_001464837.1 3826147 R 331111 CDS YP_001464838.1 157159383 5587583 complement(3827321..3828325) 1 NC_009801.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 3828325 trpS 5587583 trpS Escherichia coli E24377A tryptophanyl-tRNA synthetase YP_001464838.1 3827321 R 331111 CDS YP_001464839.1 157158678 5588271 complement(3828318..3829076) 1 NC_009801.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 3829076 gph 5588271 gph Escherichia coli E24377A phosphoglycolate phosphatase YP_001464839.1 3828318 R 331111 CDS YP_001464840.1 157155929 5589154 complement(3829069..3829746) 1 NC_009801.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 3829746 rpe 5589154 rpe Escherichia coli E24377A ribulose-phosphate 3-epimerase YP_001464840.1 3829069 R 331111 CDS YP_001464841.1 157155134 5589490 complement(3829764..3830600) 1 NC_009801.1 identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571; DNA adenine methylase 3830600 dam 5589490 dam Escherichia coli E24377A DNA adenine methylase YP_001464841.1 3829764 R 331111 CDS YP_001464842.1 157155660 5590549 complement(3830707..3831984) 1 NC_009801.1 identified by similarity to SP:P11557; match to protein family HMM PF05036; hypothetical protein 3831984 damX 5590549 damX Escherichia coli E24377A hypothetical protein YP_001464842.1 3830707 R 331111 CDS YP_001464843.1 157158844 5587826 complement(3832076..3833164) 1 NC_009801.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 3833164 aroB 5587826 aroB Escherichia coli E24377A 3-dehydroquinate synthase YP_001464843.1 3832076 R 331111 CDS YP_001464844.1 157158436 5589731 complement(3833221..3833742) 1 NC_009801.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 3833742 aroK 5589731 aroK Escherichia coli E24377A shikimate kinase I YP_001464844.1 3833221 R 331111 CDS YP_001464845.1 157158971 5588048 complement(3834143..3835381) 1 NC_009801.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ 3835381 hofQ 5588048 hofQ Escherichia coli E24377A outer membrane porin HofQ YP_001464845.1 3834143 R 331111 CDS YP_001464846.1 157157124 5586656 complement(3835293..3835697) 1 NC_009801.1 hypothetical protein 3835697 5586656 EcE24377A_3862 Escherichia coli E24377A hypothetical protein YP_001464846.1 3835293 R 331111 CDS YP_001464847.1 157157911 5585988 complement(3835687..3836127) 1 NC_009801.1 hypothetical protein 3836127 5585988 EcE24377A_3863 Escherichia coli E24377A hypothetical protein YP_001464847.1 3835687 R 331111 CDS YP_001464848.1 157155814 5587594 complement(3836111..3836650) 1 NC_009801.1 identified by match to protein family HMM PF05137; PilN family protein 3836650 5587594 EcE24377A_3865 Escherichia coli E24377A PilN family protein YP_001464848.1 3836111 R 331111 CDS YP_001464849.1 157158580 5586497 complement(3836650..3837429) 1 NC_009801.1 identified by similarity to SP:P45753; HofM protein 3837429 hofM 5586497 hofM Escherichia coli E24377A HofM protein YP_001464849.1 3836650 R 331111 CDS YP_001464850.1 157158961 5588273 3837549..3840101 1 NC_009801.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3840101 mrcA 5588273 mrcA Escherichia coli E24377A peptidoglycan synthetase YP_001464850.1 3837549 D 331111 CDS YP_001464851.1 157159327 5585950 complement(3840266..3840826) 1 NC_009801.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 3840826 nudE 5585950 nudE Escherichia coli E24377A ADP-ribose diphosphatase NudE YP_001464851.1 3840266 R 331111 CDS YP_001464852.1 157157835 5588494 3841030..3841149 1 NC_009801.1 identified by glimmer; hypothetical protein 3841149 5588494 EcE24377A_3869 Escherichia coli E24377A hypothetical protein YP_001464852.1 3841030 D 331111 CDS YP_001464853.1 157158221 5589094 3841146..3843281 1 NC_009801.1 identified by similarity to SP:P45800; match to protein family HMM PF07095; hypothetical protein 3843281 5589094 EcE24377A_3870 Escherichia coli E24377A hypothetical protein YP_001464853.1 3841146 D 331111 CDS YP_001464854.1 157156234 5590086 3843346..3844014 1 NC_009801.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; HAD family hydrolase 3844014 5590086 EcE24377A_3871 Escherichia coli E24377A HAD family hydrolase YP_001464854.1 3843346 D 331111 CDS YP_001464855.1 157156992 5586689 3844025..3844426 1 NC_009801.1 identified by similarity to SP:P0ACG8; match to protein family HMM PF01479; ribosome-associated heat shock protein Hsp15 3844426 hslR 5586689 hslR Escherichia coli E24377A ribosome-associated heat shock protein Hsp15 YP_001464855.1 3844025 D 331111 CDS YP_001464856.1 157154787 5588030 3844445..3845329 1 NC_009801.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3845329 hslO 5588030 hslO Escherichia coli E24377A Hsp33-like chaperonin YP_001464856.1 3844445 D 331111 CDS YP_001464857.1 157155320 5588579 complement(3845464..3847188) 1 NC_009801.1 identified by similarity to SP:P45804; hypothetical protein 3847188 5588579 EcE24377A_3874 Escherichia coli E24377A hypothetical protein YP_001464857.1 3845464 R 331111 CDS YP_001464858.1 157157522 5590478 complement(3847194..3847313) 1 NC_009801.1 identified by glimmer; hypothetical protein 3847313 5590478 EcE24377A_3875 Escherichia coli E24377A hypothetical protein YP_001464858.1 3847194 R 331111 CDS YP_001464859.1 157157166 5589765 complement(3847264..3847395) 1 NC_009801.1 identified by similarity to GB:AAN44882.1; hypothetical protein 3847395 5589765 EcE24377A_3876 Escherichia coli E24377A hypothetical protein YP_001464859.1 3847264 R 331111 CDS YP_001464860.1 157159150 5587501 3847567..3849189 1 NC_009801.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3849189 pckA 5587501 pckA Escherichia coli E24377A phosphoenolpyruvate carboxykinase YP_001464860.1 3847567 D 331111 CDS YP_001464861.1 157155829 5587293 complement(3849265..3850617) 1 NC_009801.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 3850617 envZ 5587293 envZ Escherichia coli E24377A osmolarity sensor protein YP_001464861.1 3849265 R 331111 CDS YP_001464862.1 157155385 5589840 complement(3850614..3851333) 1 NC_009801.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 3851333 ompR 5589840 ompR Escherichia coli E24377A osmolarity response regulator YP_001464862.1 3850614 R 331111 CDS YP_001464863.1 157155011 5586743 3851561..3852037 1 NC_009801.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3852037 greB 5586743 greB Escherichia coli E24377A transcription elongation factor GreB YP_001464863.1 3851561 D 331111 CDS YP_001464864.1 157157022 5589564 3852134..3854455 1 NC_009801.1 identified by match to protein family HMM PF00575; protein yhgF 3854455 yhgF 5589564 yhgF Escherichia coli E24377A protein yhgF YP_001464864.1 3852134 D 331111 CDS YP_001464865.1 157156080 5590253 3854490..3854582 1 NC_009801.1 identified by glimmer; hypothetical protein 3854582 5590253 EcE24377A_3882 Escherichia coli E24377A hypothetical protein YP_001464865.1 3854490 D 331111 CDS YP_001464866.1 157158012 5588771 3854893..3855120 1 NC_009801.1 identified by match to protein family HMM PF04023; ferrous iron transport protein A 3855120 feoA 5588771 feoA Escherichia coli E24377A ferrous iron transport protein A YP_001464866.1 3854893 D 331111 CDS YP_001464867.1 157157745 5589177 3855137..3857458 1 NC_009801.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3857458 feoB 5589177 feoB Escherichia coli E24377A ferrous iron transport protein B YP_001464867.1 3855137 D 331111 CDS YP_001464868.1 157156064 5589420 3857458..3857694 1 NC_009801.1 identified by match to protein family HMM PF09012; hypothetical protein 3857694 5589420 EcE24377A_3885 Escherichia coli E24377A hypothetical protein YP_001464868.1 3857458 D 331111 CDS YP_001464869.1 157157136 5590131 3857897..3858775 1 NC_009801.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784; hypothetical protein 3858775 5590131 EcE24377A_3886 Escherichia coli E24377A hypothetical protein YP_001464869.1 3857897 D 331111 CDS YP_001464870.1 157159452 5589919 complement(3858804..3859574) 1 NC_009801.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH 3859574 5589919 EcE24377A_3887 Escherichia coli E24377A carboxylesterase BioH YP_001464870.1 3858804 R 331111 CDS YP_001464871.1 157158776 5588339 3859612..3860295 1 NC_009801.1 involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3860295 gntX 5588339 gntX Escherichia coli E24377A gluconate periplasmic binding protein YP_001464871.1 3859612 D 331111 CDS YP_001464872.1 157155730 5586776 3860354..3860929 1 NC_009801.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 3860929 gntY 5586776 gntY Escherichia coli E24377A DNA uptake protein YP_001464872.1 3860354 D 331111 CDS YP_001464873.1 157155001 5590193 3861182..3861274 1 NC_009801.1 identified by glimmer; hypothetical protein 3861274 5590193 EcE24377A_3890 Escherichia coli E24377A hypothetical protein YP_001464873.1 3861182 D 331111 CDS YP_001464874.1 157156277 5586214 3861290..3862606 1 NC_009801.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791; high-affinity gluconate transporter 3862606 gntT 5586214 gntT Escherichia coli E24377A high-affinity gluconate transporter YP_001464874.1 3861290 D 331111 CDS YP_001464875.1 157156003 5590604 complement(3862651..3864735) 1 NC_009801.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 3864735 malQ 5590604 malQ Escherichia coli E24377A 4-alpha-glucanotransferase YP_001464875.1 3862651 R 331111 CDS YP_001464876.1 157157842 5589848 complement(3864745..3867138) 1 NC_009801.1 identified by similarity to SP:P00490; match to protein family HMM PF00343; match to protein family HMM TIGR02093; maltodextrin phosphorylase 3867138 malP 5589848 malP Escherichia coli E24377A maltodextrin phosphorylase YP_001464876.1 3864745 R 331111 CDS YP_001464877.1 157159429 5587299 3867750..3870455 1 NC_009801.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3870455 malT 5587299 malT Escherichia coli E24377A transcriptional regulator MalT YP_001464877.1 3867750 D 331111 CDS YP_001464878.1 157155158 5586091 complement(3870498..3871514) 1 NC_009801.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase 3871514 rtcA 5586091 rtcA Escherichia coli E24377A RNA 3'-terminal-phosphate cyclase YP_001464878.1 3870498 R 331111 CDS YP_001464879.1 157155837 5590845 3871062..3872183 1 NC_009801.1 identified by glimmer; hypothetical protein 3872183 5590845 EcE24377A_3897 Escherichia coli E24377A hypothetical protein YP_001464879.1 3871062 D 331111 CDS YP_001464880.1 157155299 5586859 complement(3871518..3872744) 1 NC_009801.1 identified by similarity to SP:P46850; match to protein family HMM PF01139; RtcB protein 3872744 rtcB 5586859 rtcB Escherichia coli E24377A RtcB protein YP_001464880.1 3871518 R 331111 CDS YP_001464881.1 157157321 5586881 3872933..3874531 1 NC_009801.1 identified by similarity to SP:P38035; match to protein family HMM PF00158; match to protein family HMM PF06956; match to protein family HMM PF07728; sigma-54 dependent transcriptional regulator RtcR 3874531 rtcR 5586881 rtcR Escherichia coli E24377A sigma-54 dependent transcriptional regulator RtcR YP_001464881.1 3872933 D 331111 CDS YP_001464882.1 157158884 5588008 complement(3874513..3875271) 1 NC_009801.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR 3875271 glpR 5588008 glpR Escherichia coli E24377A DNA-binding transcriptional repressor GlpR YP_001464882.1 3874513 R 331111 CDS YP_001464883.1 157156246 5590448 complement(3875288..3876118) 1 NC_009801.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG 3876118 5590448 EcE24377A_3900 Escherichia coli E24377A intramembrane serine protease GlpG YP_001464883.1 3875288 R 331111 CDS YP_001464884.1 157156664 5587125 complement(3876163..3876489) 1 NC_009801.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 3876489 glpE 5587125 glpE Escherichia coli E24377A thiosulfate sulfurtransferase YP_001464884.1 3876163 R 331111 CDS YP_001464885.1 157154781 5589056 3876679..3878184 1 NC_009801.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3878184 glpD 5589056 glpD Escherichia coli E24377A glycerol-3-phosphate dehydrogenase YP_001464885.1 3876679 D 331111 CDS YP_001464886.1 157155306 5586026 complement(3878238..3878843) 1 NC_009801.1 identified by similarity to GB:AAN82642.1; hypothetical protein 3878843 5586026 EcE24377A_3903 Escherichia coli E24377A hypothetical protein YP_001464886.1 3878238 R 331111 CDS YP_001464887.1 157158876 5586342 complement(3878846..3879613) 1 NC_009801.1 hypothetical protein 3879613 5586342 EcE24377A_3904 Escherichia coli E24377A hypothetical protein YP_001464887.1 3878846 R 331111 CDS YP_001464888.1 157158573 5590341 complement(3879616..3880326) 1 NC_009801.1 hypothetical protein 3880326 5590341 EcE24377A_3905 Escherichia coli E24377A hypothetical protein YP_001464888.1 3879616 R 331111 CDS YP_001464889.1 157157817 5586914 complement(3880341..3881846) 1 NC_009801.1 hypothetical protein 3881846 5586914 EcE24377A_3906 Escherichia coli E24377A hypothetical protein YP_001464889.1 3880341 R 331111 CDS YP_001464890.1 157157318 5589345 complement(3881974..3884421) 1 NC_009801.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093; glycogen phosphorylase 3884421 glgP 5589345 glgP Escherichia coli E24377A glycogen phosphorylase YP_001464890.1 3881974 R 331111 CDS YP_001464891.1 157158992 5588710 complement(3884440..3885873) 1 NC_009801.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 3885873 glgA 5588710 glgA Escherichia coli E24377A glycogen synthase YP_001464891.1 3884440 R 331111 CDS YP_001464892.1 157158326 5590526 complement(3885873..3887168) 1 NC_009801.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 3887168 glgC 5590526 glgC Escherichia coli E24377A glucose-1-phosphate adenylyltransferase YP_001464892.1 3885873 R 331111 CDS YP_001464893.1 157154823 5587748 complement(3887186..3889159) 1 NC_009801.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein 3889159 glgX 5587748 glgX Escherichia coli E24377A glycogen debranching protein YP_001464893.1 3887186 R 331111 CDS YP_001464894.1 157155505 5586828 complement(3889156..3891342) 1 NC_009801.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 3891342 glgB 5586828 glgB Escherichia coli E24377A glycogen branching protein YP_001464894.1 3889156 R 331111 CDS YP_001464895.1 157158625 5590793 complement(3891615..3892718) 1 NC_009801.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 3892718 asd 5590793 asd Escherichia coli E24377A aspartate-semialdehyde dehydrogenase YP_001464895.1 3891615 R 331111 CDS YP_001464896.1 157159283 5587269 3892911..3893504 1 NC_009801.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 3893504 5587269 EcE24377A_3913 Escherichia coli E24377A dITP- and XTP- hydrolase YP_001464896.1 3892911 D 331111 CDS YP_001464897.1 157159300 5589949 complement(3893561..3894901) 1 NC_009801.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791; low affinity gluconate transporter 3894901 gntU 5589949 gntU Escherichia coli E24377A low affinity gluconate transporter YP_001464897.1 3893561 R 331111 CDS YP_001464898.1 157159305 5590484 complement(3894905..3895432) 1 NC_009801.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 3895432 gntK 5590484 gntK Escherichia coli E24377A gluconate kinase YP_001464898.1 3894905 R 331111 CDS YP_001464899.1 157159015 5588478 complement(3895571..3896566) 1 NC_009801.1 identified by similarity to SP:P0ACP5; match to protein family HMM PF00356; match to protein family HMM PF00532; GntR family transcriptional regulator 3896566 gntR 5588478 gntR Escherichia coli E24377A GntR family transcriptional regulator YP_001464899.1 3895571 R 331111 CDS YP_001464900.1 157158486 5588212 complement(3896790..3897485) 1 NC_009801.1 identified by match to protein family HMM PF02678; match to protein family HMM PF07883; pirin 3897485 5588212 EcE24377A_3917 Escherichia coli E24377A pirin YP_001464900.1 3896790 R 331111 CDS YP_001464901.1 157155755 5590372 complement(3897608..3898645) 1 NC_009801.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; dehydrogenase 3898645 5590372 EcE24377A_3918 Escherichia coli E24377A dehydrogenase YP_001464901.1 3897608 R 331111 CDS YP_001464902.1 157154812 5589687 3898556..3898744 1 NC_009801.1 identified by glimmer; hypothetical protein 3898744 5589687 EcE24377A_3919 Escherichia coli E24377A hypothetical protein YP_001464902.1 3898556 D 331111 CDS YP_001464903.1 157158112 5587698 3898978..3899466 1 NC_009801.1 YhhY; regulated by the fur regulator; unknown function; acetyltransferase YhhY 3899466 5587698 EcE24377A_3920 Escherichia coli E24377A acetyltransferase YhhY YP_001464903.1 3898978 D 331111 CDS YP_001464904.1 157157882 5589133 3899703..3900881 1 NC_009801.1 identified by match to protein family HMM PF01844; match to protein family HMM PF05638; match to protein family HMM TIGR03344; HNH endonuclease domain-containing protein 3900881 5589133 EcE24377A_3921 Escherichia coli E24377A HNH endonuclease domain-containing protein YP_001464904.1 3899703 D 331111 CDS YP_001464905.1 157159360 5588820 3900878..3901372 1 NC_009801.1 hypothetical protein 3901372 5588820 EcE24377A_3922 Escherichia coli E24377A hypothetical protein YP_001464905.1 3900878 D 331111 CDS YP_001464906.1 157158828 5588481 3901822..3902106 1 NC_009801.1 identified by glimmer; hypothetical protein 3902106 5588481 EcE24377A_3923 Escherichia coli E24377A hypothetical protein YP_001464906.1 3901822 D 331111 CDS YP_001464907.1 157158386 5585953 complement(3902144..3903877) 1 NC_009801.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase 3903877 ggt 5585953 ggt Escherichia coli E24377A gamma-glutamyltranspeptidase YP_001464907.1 3902144 R 331111 CDS YP_001464908.1 157156547 5589293 3903843..3903965 1 NC_009801.1 identified by glimmer; hypothetical protein 3903965 5589293 EcE24377A_3925 Escherichia coli E24377A hypothetical protein YP_001464908.1 3903843 D 331111 CDS YP_001464909.1 157158212 5590201 3903998..3904438 1 NC_009801.1 hypothetical protein 3904438 5590201 EcE24377A_3927 Escherichia coli E24377A hypothetical protein YP_001464909.1 3903998 D 331111 CDS YP_001464910.1 157157691 5588361 complement(3904425..3905168) 1 NC_009801.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase 3905168 ugpQ 5588361 ugpQ Escherichia coli E24377A glycerophosphodiester phosphodiesterase YP_001464910.1 3904425 R 331111 CDS YP_001464911.1 157158729 5587183 complement(3905165..3906235) 1 NC_009801.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 3906235 ugpC 5587183 ugpC Escherichia coli E24377A glycerol-3-phosphate transporter ATP-binding subunit YP_001464911.1 3905165 R 331111 CDS YP_001464912.1 157159258 5587639 complement(3906237..3907082) 1 NC_009801.1 with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein 3907082 5587639 EcE24377A_3929 Escherichia coli E24377A glycerol-3-phosphate transporter membrane protein YP_001464912.1 3906237 R 331111 CDS YP_001464913.1 157156372 5590159 complement(3907079..3907966) 1 NC_009801.1 with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease 3907966 ugpA 5590159 ugpA Escherichia coli E24377A glycerol-3-phosphate transporter permease YP_001464913.1 3907079 R 331111 CDS YP_001464914.1 157157052 5590311 complement(3908064..3909380) 1 NC_009801.1 with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein 3909380 ugpB 5590311 ugpB Escherichia coli E24377A glycerol-3-phosphate transporter periplasmic binding protein YP_001464914.1 3908064 R 331111 CDS YP_001464915.1 157156522 5587426 complement(3909594..3909710) 1 NC_009801.1 identified by glimmer; hypothetical protein 3909710 5587426 EcE24377A_3932 Escherichia coli E24377A hypothetical protein YP_001464915.1 3909594 R 331111 CDS YP_001464916.1 157157189 5587567 complement(3909777..3910478) 1 NC_009801.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 3910478 livF 5587567 livF Escherichia coli E24377A leucine/isoleucine/valine transporter ATP-binding subunit YP_001464916.1 3909777 R 331111 CDS YP_001464917.1 157158145 5587322 complement(3910492..3911259) 1 NC_009801.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 3911259 livG 5587322 livG Escherichia coli E24377A leucine/isoleucine/valine transporter ATP-binding subunit YP_001464917.1 3910492 R 331111 CDS YP_001464918.1 157158767 5590784 complement(3911256..3912533) 1 NC_009801.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit 3912533 livM 5590784 livM Escherichia coli E24377A leucine/isoleucine/valine transporter permease subunit YP_001464918.1 3911256 R 331111 CDS YP_001464919.1 157155414 5589770 complement(3912530..3913456) 1 NC_009801.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH 3913456 livH 5589770 livH Escherichia coli E24377A branched-chain amino acid transporter permease subunit LivH YP_001464919.1 3912530 R 331111 CDS YP_001464920.1 157159223 5590272 complement(3913504..3914613) 1 NC_009801.1 identified by match to protein family HMM PF01094; high-affinity branched-chain amino acid ABC transporter periplasmic leucine-specific-binding protein LivK 3914613 livK 5590272 livK Escherichia coli E24377A high-affinity branched-chain amino acid ABC transporter periplasmic leucine-specific-binding protein LivK YP_001464920.1 3913504 R 331111 CDS YP_001464921.1 157155467 5586531 complement(3914765..3914902) 1 NC_009801.1 identified by glimmer; hypothetical protein 3914902 5586531 EcE24377A_3938 Escherichia coli E24377A hypothetical protein YP_001464921.1 3914765 R 331111 CDS YP_001464922.1 157154958 5588878 3915037..3915420 1 NC_009801.1 identified by match to protein family HMM PF00583; acetyltransferase 3915420 5588878 EcE24377A_3940 Escherichia coli E24377A acetyltransferase YP_001464922.1 3915037 D 331111 CDS YP_001464923.1 157157866 5587903 complement(3915417..3915944) 1 NC_009801.1 hypothetical protein 3915944 5587903 EcE24377A_3939 Escherichia coli E24377A hypothetical protein YP_001464923.1 3915417 R 331111 CDS YP_001464924.1 157157355 5586098 complement(3915951..3916217) 1 NC_009801.1 identified by similarity to GB:AAX67401.1; match to protein family HMM PF08681; hypothetical protein 3916217 5586098 EcE24377A_3941 Escherichia coli E24377A hypothetical protein YP_001464924.1 3915951 R 331111 CDS YP_001464925.1 157158994 5590120 complement(3916367..3917470) 1 NC_009801.1 identified by match to protein family HMM PF01094; high-affinity branched-chain amino acid ABC transporter periplasmic Leu/Ile/Val-binding protein LivJ 3917470 livJ 5590120 livJ Escherichia coli E24377A high-affinity branched-chain amino acid ABC transporter periplasmic Leu/Ile/Val-binding protein LivJ YP_001464925.1 3916367 R 331111 CDS YP_001464926.1 157158396 5588026 complement(3917741..3918595) 1 NC_009801.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 3918595 rpoH 5588026 rpoH Escherichia coli E24377A RNA polymerase factor sigma-32 YP_001464926.1 3917741 R 331111 CDS YP_001464927.1 157155892 5587849 complement(3918840..3919898) 1 NC_009801.1 ABC transporter membrane protein; cell division protein FtsX 3919898 ftsX 5587849 ftsX Escherichia coli E24377A cell division protein FtsX YP_001464927.1 3918840 R 331111 CDS YP_001464928.1 157155266 5587782 complement(3919891..3920559) 1 NC_009801.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE 3920559 ftsE 5587782 ftsE Escherichia coli E24377A cell division protein FtsE YP_001464928.1 3919891 R 331111 CDS YP_001464929.1 157158382 5587997 complement(3920562..3922055) 1 NC_009801.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY 3922055 ftsY 5587997 ftsY Escherichia coli E24377A cell division protein FtsY YP_001464929.1 3920562 R 331111 CDS YP_001464930.1 157155481 5587436 3922205..3922801 1 NC_009801.1 catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 3922801 rsmD 5587436 rsmD Escherichia coli E24377A 16S rRNA m(2)G966-methyltransferase YP_001464930.1 3922205 D 331111 CDS YP_001464931.1 157159309 5586788 3922791..3923060 1 NC_009801.1 identified by match to protein family HMM PF06611; hypothetical protein 3923060 5586788 EcE24377A_3948 Escherichia coli E24377A hypothetical protein YP_001464931.1 3922791 D 331111 CDS YP_001464932.1 157158649 5588999 complement(3923063..3923422) 1 NC_009801.1 identified by similarity to GB:CAG77246.1; hypothetical protein 3923422 5588999 EcE24377A_3949 Escherichia coli E24377A hypothetical protein YP_001464932.1 3923063 R 331111 CDS YP_001464933.1 157156477 5588751 3923563..3924189 1 NC_009801.1 identified by match to protein family HMM PF07947; hypothetical protein 3924189 5588751 EcE24377A_3950 Escherichia coli E24377A hypothetical protein YP_001464933.1 3923563 D 331111 CDS YP_001464934.1 157158079 5589084 3924263..3926461 1 NC_009801.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 3926461 zntA 5589084 zntA Escherichia coli E24377A zinc/cadmium/mercury/lead-transporting ATPase YP_001464934.1 3924263 D 331111 CDS YP_001464935.1 157154829 5589429 complement(3926563..3926808) 1 NC_009801.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 3926808 tusA 5589429 tusA Escherichia coli E24377A sulfur transfer protein SirA YP_001464935.1 3926563 R 331111 CDS YP_001464936.1 157157060 5586619 3927029..3927694 1 NC_009801.1 identified by match to protein family HMM PF02592; match to protein family HMM TIGR00697; hypothetical protein 3927694 5586619 EcE24377A_3953 Escherichia coli E24377A hypothetical protein YP_001464936.1 3927029 D 331111 CDS YP_001464937.1 157159222 5589379 3927767..3928324 1 NC_009801.1 hypothetical protein 3928324 5589379 EcE24377A_3954 Escherichia coli E24377A hypothetical protein YP_001464937.1 3927767 D 331111 CDS YP_001464938.1 157158768 5590717 complement(3928328..3929587) 1 NC_009801.1 identified by match to protein family HMM PF07690; major facilitator superfamily transporter 3929587 5590717 EcE24377A_3955 Escherichia coli E24377A major facilitator superfamily transporter YP_001464938.1 3928328 R 331111 CDS YP_001464939.1 157157615 5587887 3929677..3930726 1 NC_009801.1 identified by match to protein family HMM PF01594; hypothetical protein 3930726 5587887 EcE24377A_3956 Escherichia coli E24377A hypothetical protein YP_001464939.1 3929677 D 331111 CDS YP_001464940.1 157159328 5589614 3930781..3931368 1 NC_009801.1 identified by similarity to SP:P37623; match to protein family HMM PF01648; holo-(acyl carrier protein) synthase 2 3931368 acpT 5589614 acpT Escherichia coli E24377A holo-(acyl carrier protein) synthase 2 YP_001464940.1 3930781 D 331111 CDS YP_001464941.1 157156241 5589100 3931479..3933053 1 NC_009801.1 identified by match to protein family HMM PF00496; match to protein family HMM TIGR02294; nickel ABC transporter periplasmic nickel-binding protein NikA 3933053 nikA 5589100 nikA Escherichia coli E24377A nickel ABC transporter periplasmic nickel-binding protein NikA YP_001464941.1 3931479 D 331111 CDS YP_001464942.1 157157383 5586242 3933053..3933997 1 NC_009801.1 with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 3933997 nikB 5586242 nikB Escherichia coli E24377A nickel transporter permease NikB YP_001464942.1 3933053 D 331111 CDS YP_001464943.1 157154967 5589652 3933978..3934097 1 NC_009801.1 identified by glimmer; hypothetical protein 3934097 5589652 EcE24377A_3960 Escherichia coli E24377A hypothetical protein YP_001464943.1 3933978 D 331111 CDS YP_001464944.1 157158783 5588719 3933994..3934827 1 NC_009801.1 with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 3934827 nikC 5588719 nikC Escherichia coli E24377A nickel transporter permease NikC YP_001464944.1 3933994 D 331111 CDS YP_001464945.1 157156946 5587208 complement(3934760..3935524) 1 NC_009801.1 identified by glimmer; hypothetical protein 3935524 5587208 EcE24377A_3961 Escherichia coli E24377A hypothetical protein YP_001464945.1 3934760 R 331111 CDS YP_001464946.1 157155896 5587531 3934827..3935591 1 NC_009801.1 with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 3935591 nikD 5587531 nikD Escherichia coli E24377A nickel transporter ATP-binding protein NikD YP_001464946.1 3934827 D 331111 CDS YP_001464947.1 157156923 5587320 3935588..3936394 1 NC_009801.1 with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 3936394 nikE 5587320 nikE Escherichia coli E24377A nickel transporter ATP-binding protein NikE YP_001464947.1 3935588 D 331111 CDS YP_001464948.1 157158189 5588401 3936400..3936801 1 NC_009801.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 3936801 nikR 5588401 nikR Escherichia coli E24377A nickel responsive regulator YP_001464948.1 3936400 D 331111 CDS YP_001464949.1 157156731 5589046 complement(3936921..3937280) 1 NC_009801.1 identified by match to protein family HMM PF05534; HicB family protein 3937280 5589046 EcE24377A_3966 Escherichia coli E24377A HicB family protein YP_001464949.1 3936921 R 331111 CDS YP_001464950.1 157156188 5586915 complement(3937611..3938735) 1 NC_009801.1 identified by match to protein family HMM PF01061; ABC transporter ATP-binding protein 3938735 5586915 EcE24377A_3967 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001464950.1 3937611 R 331111 CDS YP_001464951.1 157155368 5588680 complement(3938735..3941470) 1 NC_009801.1 identified by match to protein family HMM PF00005; match to protein family HMM PF01061; ABC transporter ATP-binding protein 3941470 5588680 EcE24377A_3968 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001464951.1 3938735 R 331111 CDS YP_001464952.1 157154833 5588051 complement(3941467..3942321) 1 NC_009801.1 identified by match to protein family HMM PF00529; MFP family transporter 3942321 5588051 EcE24377A_3969 Escherichia coli E24377A MFP family transporter YP_001464952.1 3941467 R 331111 CDS YP_001464953.1 157155399 5586363 complement(3942687..3944309) 1 NC_009801.1 identified by similarity to GB:AAP19219.1; hypothetical protein 3944309 5586363 EcE24377A_3970 Escherichia coli E24377A hypothetical protein YP_001464953.1 3942687 R 331111 CDS YP_001464954.1 157154714 5586222 complement(3944571..3946160) 1 NC_009801.1 identified by similarity to GB:AAZ90271.1; hypothetical protein 3946160 5586222 EcE24377A_3971 Escherichia coli E24377A hypothetical protein YP_001464954.1 3944571 R 331111 CDS YP_001464955.1 157159459 5586357 3946544..3947596 1 NC_009801.1 hypothetical protein 3947596 5586357 EcE24377A_3972 Escherichia coli E24377A hypothetical protein YP_001464955.1 3946544 D 331111 CDS YP_001464956.1 157158737 5590871 complement(3947676..3947789) 1 NC_009801.1 identified by glimmer; hypothetical protein 3947789 5590871 EcE24377A_3973 Escherichia coli E24377A hypothetical protein YP_001464956.1 3947676 R 331111 CDS YP_001464957.1 157158106 5589639 complement(3947912..3949114) 1 NC_009801.1 identified by match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275; pyridine nucleotide-disulfide oxidoreductase 3949114 5589639 EcE24377A_3974 Escherichia coli E24377A pyridine nucleotide-disulfide oxidoreductase YP_001464957.1 3947912 R 331111 CDS YP_001464958.1 157156940 5587621 3949346..3950845 1 NC_009801.1 identified by match to protein family HMM PF01384; low-affinity inorganic phosphate transporter 1 3950845 pitA 5587621 pitA Escherichia coli E24377A low-affinity inorganic phosphate transporter 1 YP_001464958.1 3949346 D 331111 CDS YP_001464959.1 157155876 5588080 complement(3950916..3951251) 1 NC_009801.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 3951251 uspB 5588080 uspB Escherichia coli E24377A universal stress protein UspB YP_001464959.1 3950916 R 331111 CDS YP_001464960.1 157155224 5589861 3951642..3952076 1 NC_009801.1 identified by similarity to SP:P0AED0; match to protein family HMM PF00582; universal stress protein A 3952076 uspA 5589861 uspA Escherichia coli E24377A universal stress protein A YP_001464960.1 3951642 D 331111 CDS YP_001464961.1 157154827 5588926 3952394..3953863 1 NC_009801.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 3953863 5588926 EcE24377A_3978 Escherichia coli E24377A inner membrane transporter YhiP YP_001464961.1 3952394 D 331111 CDS YP_001464962.1 157158928 5586628 complement(3953912..3954664) 1 NC_009801.1 predicted SAM-dependent methyltransferase; methyltransferase 3954664 5586628 EcE24377A_3979 Escherichia coli E24377A methyltransferase YP_001464962.1 3953912 R 331111 CDS YP_001464963.1 157159202 5586793 complement(3954672..3956714) 1 NC_009801.1 identified by similarity to SP:P27298; match to protein family HMM PF01432; oligopeptidase A 3956714 prlC 5586793 prlC Escherichia coli E24377A oligopeptidase A YP_001464963.1 3954672 R 331111 CDS YP_001464964.1 157158825 5590657 3956917..3957759 1 NC_009801.1 identified by similarity to SP:P37634; match to protein family HMM PF04378; DNA utilization protein YhiR 3957759 yhiR 5590657 yhiR Escherichia coli E24377A DNA utilization protein YhiR YP_001464964.1 3956917 D 331111 CDS YP_001464965.1 157158049 5587450 3957831..3959183 1 NC_009801.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 3959183 gor 5587450 gor Escherichia coli E24377A glutathione reductase YP_001464965.1 3957831 D 331111 CDS YP_001464966.1 157157543 5586088 complement(3959237..3959386) 1 NC_009801.1 identified by glimmer; hypothetical protein 3959386 5586088 EcE24377A_3983 Escherichia coli E24377A hypothetical protein YP_001464966.1 3959237 R 331111 CDS YP_001464967.1 157156719 5588421 3960060..3960413 1 NC_009801.1 regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 3960413 arsR 5588421 arsR Escherichia coli E24377A DNA-binding transcriptional repressor ArsR YP_001464967.1 3960060 D 331111 CDS YP_001464968.1 157154715 5588464 3960467..3961756 1 NC_009801.1 identified by match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935; arsenical pump membrane protein 3961756 arsB 5588464 arsB Escherichia coli E24377A arsenical pump membrane protein YP_001464968.1 3960467 D 331111 CDS YP_001464969.1 157155271 5588014 3961769..3962194 1 NC_009801.1 identified by similarity to SP:P08692; match to protein family HMM PF03960; match to protein family HMM TIGR00014; arsenate reductase 3962194 arsC 5588014 arsC Escherichia coli E24377A arsenate reductase YP_001464969.1 3961769 D 331111 CDS YP_001464970.1 157158997 5586565 3962227..3962355 1 NC_009801.1 identified by glimmer; hypothetical protein 3962355 5586565 EcE24377A_3988 Escherichia coli E24377A hypothetical protein YP_001464970.1 3962227 D 331111 CDS YP_001464971.1 157155792 5588044 complement(3962317..3962613) 1 NC_009801.1 identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 3962613 5588044 EcE24377A_3987 Escherichia coli E24377A ArsR family transcriptional regulator YP_001464971.1 3962317 R 331111 CDS YP_001464972.1 157154760 5590462 3962721..3963722 1 NC_009801.1 identified by match to protein family HMM PF03773; permease 3963722 5590462 EcE24377A_3989 Escherichia coli E24377A permease YP_001464972.1 3962721 D 331111 CDS YP_001464973.1 157157739 5587663 3964303..3965148 1 NC_009801.1 identified by similarity to GB:ABB67989.1; hypothetical protein 3965148 5587663 EcE24377A_3990 Escherichia coli E24377A hypothetical protein YP_001464973.1 3964303 D 331111 CDS YP_001464974.1 157158425 5590735 3965343..3965525 1 NC_009801.1 hypothetical protein 3965525 5590735 EcE24377A_3991 Escherichia coli E24377A hypothetical protein YP_001464974.1 3965343 D 331111 CDS YP_001464975.1 157157056 5586106 3965772..3966338 1 NC_009801.1 identified by match to protein family HMM PF03843; match to protein family HMM TIGR00752; Slp family outer membrane lipoprotein 3966338 5586106 EcE24377A_3992 Escherichia coli E24377A Slp family outer membrane lipoprotein YP_001464975.1 3965772 D 331111 CDS YP_001464976.1 157157438 5587376 3966494..3967024 1 NC_009801.1 identified by similarity to SP:P37195; match to protein family HMM PF00196; transcriptional regulator DctR 3967024 dctR 5587376 dctR Escherichia coli E24377A transcriptional regulator DctR YP_001464976.1 3966494 D 331111 CDS YP_001464977.1 157155965 5590219 complement(3967066..3967713) 1 NC_009801.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase 3967713 5590219 EcE24377A_3994 Escherichia coli E24377A Mg(2+) transport ATPase YP_001464977.1 3967066 R 331111 CDS YP_001464978.1 157158063 5586227 complement(3967777..3968115) 1 NC_009801.1 acid-resistance protein 3968115 hdeB 5586227 hdeB Escherichia coli E24377A acid-resistance protein YP_001464978.1 3967777 R 331111 CDS YP_001464979.1 157158855 5586896 complement(3968219..3968551) 1 NC_009801.1 inactive form; acid-resistance protein 3968551 hdeA 5586896 hdeA Escherichia coli E24377A acid-resistance protein YP_001464979.1 3968219 R 331111 CDS YP_001464980.1 157159293 5589825 3968806..3969378 1 NC_009801.1 identified by similarity to SP:P0AET7; acid-resistance membrane protein 3969378 5589825 EcE24377A_3997 Escherichia coli E24377A acid-resistance membrane protein YP_001464980.1 3968806 D 331111 CDS YP_001464981.1 157157442 5588828 3970177..3970704 1 NC_009801.1 identified by similarity to SP:P63204; transcriptional regulator GadE 3970704 gadE 5588828 gadE Escherichia coli E24377A transcriptional regulator GadE YP_001464981.1 3970177 D 331111 CDS YP_001464982.1 157158536 5586760 3971043..3972200 1 NC_009801.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 3972200 mdtE 5586760 mdtE Escherichia coli E24377A multidrug efflux system protein MdtE YP_001464982.1 3971043 D 331111 CDS YP_001464983.1 157156681 5587271 3972225..3975338 1 NC_009801.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; multidrug resistance protein MdtF 3975338 mdtF 5587271 mdtF Escherichia coli E24377A multidrug resistance protein MdtF YP_001464983.1 3972225 D 331111 CDS YP_001464984.1 157157215 5587795 complement(3975701..3976429) 1 NC_009801.1 identified by similarity to SP:P63201; match to protein family HMM PF00165; transcriptional regulator GadW 3976429 gadW 5587795 gadW Escherichia coli E24377A transcriptional regulator GadW YP_001464984.1 3975701 R 331111 CDS YP_001464985.1 157155338 5586272 complement(3976502..3976609) 1 NC_009801.1 identified by glimmer; hypothetical protein 3976609 5586272 EcE24377A_4002 Escherichia coli E24377A hypothetical protein YP_001464985.1 3976502 R 331111 CDS YP_001464986.1 157157443 5586574 complement(3976797..3977621) 1 NC_009801.1 regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX 3977621 gadX 5586574 gadX Escherichia coli E24377A DNA-binding transcriptional regulator GadX YP_001464986.1 3976797 R 331111 CDS YP_001464987.1 157155719 5586761 3977273..3977425 1 NC_009801.1 identified by glimmer; hypothetical protein 3977425 5586761 EcE24377A_4004 Escherichia coli E24377A hypothetical protein YP_001464987.1 3977273 D 331111 CDS YP_001464988.1 157158967 5588040 complement(3977991..3979391) 1 NC_009801.1 identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; glutamate decarboxylase 3979391 gadA 5588040 gadA Escherichia coli E24377A glutamate decarboxylase YP_001464988.1 3977991 R 331111 CDS YP_001464989.1 157154859 5586140 3981403..3983052 1 NC_009801.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 3983052 treF 5586140 treF Escherichia coli E24377A trehalase YP_001464989.1 3981403 D 331111 CDS YP_001464990.1 157155556 5590700 complement(3983103..3983705) 1 NC_009801.1 identified by match to protein family HMM PF00196; match to protein family HMM PF04545; match to protein family HMM PF08281; LuxR family transcriptional regulator 3983705 5590700 EcE24377A_4008 Escherichia coli E24377A LuxR family transcriptional regulator YP_001464990.1 3983103 R 331111 CDS YP_001464991.1 157157897 5590435 3984225..3985124 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 3985124 5590435 EcE24377A_4009 Escherichia coli E24377A LysR family transcriptional regulator YP_001464991.1 3984225 D 331111 CDS YP_001464992.1 157157396 5588056 3985173..3986186 1 NC_009801.1 identified by match to protein family HMM PF03631; match to protein family HMM TIGR00766; ribonuclease 3986186 5588056 EcE24377A_4010 Escherichia coli E24377A ribonuclease YP_001464992.1 3985173 D 331111 CDS YP_001464993.1 157156887 5589409 3986597..3987919 1 NC_009801.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883; MFS transporter metabolite:H+ symporter (MHS) family protein 3987919 5589409 EcE24377A_4011 Escherichia coli E24377A MFS transporter metabolite:H+ symporter (MHS) family protein YP_001464993.1 3986597 D 331111 CDS YP_001464994.1 157156366 5588661 complement(3988153..3990213) 1 NC_009801.1 identified by match to protein family HMM PF05170; AsmA family protein 3990213 5588661 EcE24377A_4012 Escherichia coli E24377A AsmA family protein YP_001464994.1 3988153 R 331111 CDS YP_001464995.1 157155034 5588366 complement(3990283..3991050) 1 NC_009801.1 in Escherichia coli this protein is involved in flagellar function; diguanylate phosphodiesterase 3991050 5588366 EcE24377A_4013 Escherichia coli E24377A diguanylate phosphodiesterase YP_001464995.1 3990283 R 331111 CDS YP_001464996.1 157157550 5589610 3991282..3992211 1 NC_009801.1 identified by similarity to SP:P45416; match to protein family HMM PF00294; 2-dehydro-3-deoxygluconokinase 3992211 kdgK 5589610 kdgK Escherichia coli E24377A 2-dehydro-3-deoxygluconokinase YP_001464996.1 3991282 D 331111 CDS YP_001464997.1 157156623 5590422 complement(3992307..3993803) 1 NC_009801.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; M16 family peptidase 3993803 5590422 EcE24377A_4015 Escherichia coli E24377A M16 family peptidase YP_001464997.1 3992307 R 331111 CDS YP_001464998.1 157156520 5586367 complement(3994024..3995310) 1 NC_009801.1 involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 3995310 dctA 5586367 dctA Escherichia coli E24377A C4-dicarboxylate transporter DctA YP_001464998.1 3994024 R 331111 CDS YP_001464999.1 157155547 5587022 complement(3995493..3997448) 1 NC_009801.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase from E. coli; phosphodiesterase 3997448 5587022 EcE24377A_4017 Escherichia coli E24377A phosphodiesterase YP_001464999.1 3995493 R 331111 CDS YP_001465000.1 157154865 5590269 complement(3997563..4000985) 1 NC_009801.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC 4000985 bcsC 5590269 bcsC Escherichia coli E24377A cellulose synthase subunit BcsC YP_001465000.1 3997563 R 331111 CDS YP_001465001.1 157156981 5590843 complement(4001018..4002115) 1 NC_009801.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase 4002115 bcsZ 5590843 bcsZ Escherichia coli E24377A endo-1,4-D-glucanase YP_001465001.1 4001018 R 331111 CDS YP_001465002.1 157156498 5589747 complement(4002131..4004470) 1 NC_009801.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 4004470 bcsB 5589747 bcsB Escherichia coli E24377A cellulose synthase regulator protein YP_001465002.1 4002131 R 331111 CDS YP_001465003.1 157155670 5587239 complement(4004481..4007099) 1 NC_009801.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit 4007099 bcsA 5587239 bcsA Escherichia coli E24377A cellulose synthase catalytic subunit YP_001465003.1 4004481 R 331111 CDS YP_001465004.1 157155125 5587263 complement(4007096..4007848) 1 NC_009801.1 identified by match to protein family HMM PF06564; match to protein family HMM TIGR03371; cell division protein 4007848 5587263 EcE24377A_4022 Escherichia coli E24377A cell division protein YP_001465004.1 4007096 R 331111 CDS YP_001465005.1 157158461 5586933 complement(4007860..4008048) 1 NC_009801.1 hypothetical protein 4008048 5586933 EcE24377A_4023 Escherichia coli E24377A hypothetical protein YP_001465005.1 4007860 R 331111 CDS YP_001465006.1 157156797 5586001 4008387..4009892 1 NC_009801.1 identified by match to protein family HMM TIGR03369; hypothetical protein 4009892 5586001 EcE24377A_4024 Escherichia coli E24377A hypothetical protein YP_001465006.1 4008387 D 331111 CDS YP_001465007.1 157156763 5588312 4009889..4010080 1 NC_009801.1 identified by similarity to SP:P0ADJ5; cellulose biosynthesis protein BcsF 4010080 bcsF 5588312 bcsF Escherichia coli E24377A cellulose biosynthesis protein BcsF YP_001465007.1 4009889 D 331111 CDS YP_001465008.1 157157989 5589700 4010077..4011756 1 NC_009801.1 identified by similarity to GB:BAB37841.1; match to protein family HMM TIGR03368; hypothetical protein 4011756 5589700 EcE24377A_4026 Escherichia coli E24377A hypothetical protein YP_001465008.1 4010077 D 331111 CDS YP_001465009.1 157157448 5586144 complement(4012212..4012319) 1 NC_009801.1 identified by glimmer; hypothetical protein 4012319 5586144 EcE24377A_4027 Escherichia coli E24377A hypothetical protein YP_001465009.1 4012212 R 331111 CDS YP_001465010.1 157159368 5590388 complement(4012326..4012568) 1 NC_009801.1 identified by similarity to GB:AAN45023.1; hypothetical protein 4012568 5590388 EcE24377A_4028 Escherichia coli E24377A hypothetical protein YP_001465010.1 4012326 R 331111 CDS YP_001465011.1 157158864 5589732 complement(4013081..4013242) 1 NC_009801.1 identified by glimmer; hypothetical protein 4013242 5589732 EcE24377A_4030 Escherichia coli E24377A hypothetical protein YP_001465011.1 4013081 R 331111 CDS YP_001465012.1 157155310 5589590 4013392..4014663 1 NC_009801.1 identified by match to protein family HMM TIGR00814; serine transporter family protein 4014663 5589590 EcE24377A_4031 Escherichia coli E24377A serine transporter family protein YP_001465012.1 4013392 D 331111 CDS YP_001465013.1 157154821 5590444 complement(4014693..4015697) 1 NC_009801.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 4015697 dppF 5590444 dppF Escherichia coli E24377A dipeptide transporter ATP-binding subunit YP_001465013.1 4014693 R 331111 CDS YP_001465014.1 157158362 5586926 complement(4015694..4016677) 1 NC_009801.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 4016677 dppD 5586926 dppD Escherichia coli E24377A dipeptide transporter ATP-binding subunit YP_001465014.1 4015694 R 331111 CDS YP_001465015.1 157158176 5587283 complement(4016688..4017590) 1 NC_009801.1 identified by match to protein family HMM PF00528; dipeptide transporter 4017590 dppC 5587283 dppC Escherichia coli E24377A dipeptide transporter YP_001465015.1 4016688 R 331111 CDS YP_001465016.1 157158002 5587393 complement(4017600..4018619) 1 NC_009801.1 transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB 4018619 dppB 5587393 dppB Escherichia coli E24377A dipeptide transporter permease DppB YP_001465016.1 4017600 R 331111 CDS YP_001465018.1 157159059 5586739 complement(4018927..4020534) 1 NC_009801.1 identified by match to protein family HMM PF00496; dipeptide ABC transporter periplasmic dipeptide-binding protein 4020534 dppA 5586739 dppA Escherichia coli E24377A dipeptide ABC transporter periplasmic dipeptide-binding protein YP_001465018.1 4018927 R 331111 CDS YP_001465019.1 157158337 5590617 4020723..4020878 1 NC_009801.1 identified by glimmer; hypothetical protein 4020878 5590617 EcE24377A_4038 Escherichia coli E24377A hypothetical protein YP_001465019.1 4020723 D 331111 CDS YP_001465020.1 157154744 5590623 4021378..4022358 1 NC_009801.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 4022358 5590623 EcE24377A_4039 Escherichia coli E24377A IS621, transposase YP_001465020.1 4021378 D 331111 CDS YP_001465021.1 157155176 5587933 complement(4022894..4024585) 1 NC_009801.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase 4024585 5587933 EcE24377A_4041 Escherichia coli E24377A phosphoethanolamine transferase YP_001465021.1 4022894 R 331111 CDS YP_001465022.1 157156915 5588265 complement(4024909..4026117) 1 NC_009801.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00890; major facilitator family transporter 4026117 5588265 EcE24377A_4042 Escherichia coli E24377A major facilitator family transporter YP_001465022.1 4024909 R 331111 CDS YP_001465023.1 157156251 5589195 complement(4026346..4027044) 1 NC_009801.1 identified by similarity to SP:P37663; hypothetical protein 4027044 5589195 EcE24377A_4043 Escherichia coli E24377A hypothetical protein YP_001465023.1 4026346 R 331111 CDS YP_001465024.1 157158800 5586942 4027202..4027765 1 NC_009801.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyladenine DNA glycosylase 4027765 tag 5586942 tag Escherichia coli E24377A 3-methyladenine DNA glycosylase YP_001465024.1 4027202 D 331111 CDS YP_001465025.1 157158159 5588672 4027762..4028202 1 NC_009801.1 identified by match to protein family HMM PF00583; hypothetical protein 4028202 5588672 EcE24377A_4046 Escherichia coli E24377A hypothetical protein YP_001465025.1 4027762 D 331111 CDS YP_001465026.1 157157784 5586148 complement(4028171..4030504) 1 NC_009801.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; biotin sulfoxide reductase 4030504 bisC 5586148 bisC Escherichia coli E24377A biotin sulfoxide reductase YP_001465026.1 4028171 R 331111 CDS YP_001465027.1 157158823 5590475 4030657..4031316 1 NC_009801.1 identified by similarity to SP:P37665; match to protein family HMM PF00691; match to protein family HMM PF05433; outer membrane lipoprotein 4031316 5590475 EcE24377A_4047 Escherichia coli E24377A outer membrane lipoprotein YP_001465027.1 4030657 D 331111 CDS YP_001465028.1 157159315 5586839 4031332..4031457 1 NC_009801.1 identified by glimmer; hypothetical protein 4031457 5586839 EcE24377A_4048 Escherichia coli E24377A hypothetical protein YP_001465028.1 4031332 D 331111 CDS YP_001465029.1 157155889 5590663 4031420..4032394 1 NC_009801.1 identified by similarity to SP:P37666; match to protein family HMM PF00389; match to protein family HMM PF02826; 2-ketogluconate reductase 4032394 tkrA 5590663 tkrA Escherichia coli E24377A 2-ketogluconate reductase YP_001465029.1 4031420 D 331111 CDS YP_001465030.1 157158777 5587444 complement(4032444..4033154) 1 NC_009801.1 lipoprotein 4033154 5587444 EcE24377A_4050 Escherichia coli E24377A lipoprotein YP_001465030.1 4032444 R 331111 CDS YP_001465031.1 157154791 5586777 4033588..4033878 1 NC_009801.1 identified by similarity to SP:P0A9V5; transcriptional regulator 4033878 5586777 EcE24377A_4051 Escherichia coli E24377A transcriptional regulator YP_001465031.1 4033588 D 331111 CDS YP_001465032.1 157155319 5588347 4034159..4034371 1 NC_009801.1 identified by match to protein family HMM PF00313; major cold shock protein 4034371 5588347 EcE24377A_4052 Escherichia coli E24377A major cold shock protein YP_001465032.1 4034159 D 331111 CDS YP_001465033.1 157157721 5590477 complement(4034559..4034711) 1 NC_009801.1 identified by match to protein family HMM PF01848; small toxic polypeptide 4034711 hokA 5590477 hokA Escherichia coli E24377A small toxic polypeptide YP_001465033.1 4034559 R 331111 CDS YP_001465034.1 157156177 5589275 complement(4035037..4037106) 1 NC_009801.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 4037106 glyS 5589275 glyS Escherichia coli E24377A glycyl-tRNA synthetase subunit beta YP_001465034.1 4035037 R 331111 CDS YP_001465035.1 157159336 5589256 complement(4037116..4038027) 1 NC_009801.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 4038027 glyQ 5589256 glyQ Escherichia coli E24377A glycyl-tRNA synthetase subunit alpha YP_001465035.1 4037116 R 331111 CDS YP_001465036.1 157158831 5590703 complement(4038122..4038421) 1 NC_009801.1 hypothetical protein 4038421 5590703 EcE24377A_4056 Escherichia coli E24377A hypothetical protein YP_001465036.1 4038122 R 331111 CDS YP_001465037.1 157155350 5586265 4038596..4039591 1 NC_009801.1 identified by match to protein family HMM PF01757; acyltransferase 4039591 5586265 EcE24377A_4057 Escherichia coli E24377A acyltransferase YP_001465037.1 4038596 D 331111 CDS YP_001465038.1 157154845 5590595 complement(4039633..4040070) 1 NC_009801.1 identified by match to protein family HMM PF05360; hypothetical protein 4040070 5590595 EcE24377A_4058 Escherichia coli E24377A hypothetical protein YP_001465038.1 4039633 R 331111 CDS YP_001465039.1 157156182 5586253 complement(4040116..4040457) 1 NC_009801.1 identified by match to protein family HMM PF05360; hypothetical protein 4040457 5586253 EcE24377A_4059 Escherichia coli E24377A hypothetical protein YP_001465039.1 4040116 R 331111 CDS YP_001465040.1 157155057 5589269 complement(4040626..4042080) 1 NC_009801.1 identified by similarity to SP:P29444; match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01312; xylulokinase 4042080 xylB 5589269 xylB Escherichia coli E24377A xylulokinase YP_001465040.1 4040626 R 331111 CDS YP_001465041.1 157157106 5586302 complement(4042152..4043474) 1 NC_009801.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 4043474 xylA 5586302 xylA Escherichia coli E24377A xylose isomerase YP_001465041.1 4042152 R 331111 CDS YP_001465042.1 157156386 5587110 4043840..4044832 1 NC_009801.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 4044832 xylF 5587110 xylF Escherichia coli E24377A D-xylose transporter subunit XylF YP_001465042.1 4043840 D 331111 CDS YP_001465043.1 157158341 5589078 4044910..4046451 1 NC_009801.1 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 4046451 xylG 5589078 xylG Escherichia coli E24377A xylose transporter ATP-binding subunit YP_001465043.1 4044910 D 331111 CDS YP_001465044.1 157158260 5587482 4046429..4047610 1 NC_009801.1 identified by match to protein family HMM PF02653; D-xylose ABC transporter permease 4047610 xylH 5587482 xylH Escherichia coli E24377A D-xylose ABC transporter permease YP_001465044.1 4046429 D 331111 CDS YP_001465045.1 157155828 5588910 4047688..4048866 1 NC_009801.1 identified by match to protein family HMM PF00165; xylose operon regulatory protein 4048866 xylR 5588910 xylR Escherichia coli E24377A xylose operon regulatory protein YP_001465045.1 4047688 D 331111 CDS YP_001465046.1 157155273 5589839 complement(4048974..4049798) 1 NC_009801.1 identified by match to protein family HMM PF01832; hypothetical protein 4049798 bax 5589839 bax Escherichia coli E24377A hypothetical protein YP_001465046.1 4048974 R 331111 CDS YP_001465047.1 157158372 5588951 4050118..4052148 1 NC_009801.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 4052148 malS 5588951 malS Escherichia coli E24377A periplasmic alpha-amylase YP_001465047.1 4050118 D 331111 CDS YP_001465048.1 157156349 5586081 4052326..4053579 1 NC_009801.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 4053579 avtA 5586081 avtA Escherichia coli E24377A valine--pyruvate transaminase YP_001465048.1 4052326 D 331111 CDS YP_001465049.1 157157371 5586395 complement(4053730..4054203) 1 NC_009801.1 identified by match to protein family HMM PF00037; 4Fe-4S ferredoxin 4054203 5586395 EcE24377A_4070 Escherichia coli E24377A 4Fe-4S ferredoxin YP_001465049.1 4053730 R 331111 CDS YP_001465050.1 157156720 5587861 complement(4054305..4055117) 1 NC_009801.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339; IclR family transcriptional regulator 4055117 5587861 EcE24377A_4071 Escherichia coli E24377A IclR family transcriptional regulator YP_001465050.1 4054305 R 331111 CDS YP_001465051.1 157156962 5588465 4055354..4056352 1 NC_009801.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 4056352 dlgD 5588465 dlgD Escherichia coli E24377A 2,3-diketo-L-gulonate reductase YP_001465051.1 4055354 D 331111 CDS YP_001465052.1 157158283 5590479 4056364..4056831 1 NC_009801.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 4056831 5590479 EcE24377A_4073 Escherichia coli E24377A hypothetical protein YP_001465052.1 4056364 D 331111 CDS YP_001465053.1 157155519 5588648 4056949..4057422 1 NC_009801.1 membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease YiaM 4057422 5588648 EcE24377A_4074 Escherichia coli E24377A 2,3-diketo-L-gulonate TRAP transporter small permease YiaM YP_001465053.1 4056949 D 331111 CDS YP_001465054.1 157158213 5590047 4057425..4058702 1 NC_009801.1 identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786; TRAP transporter DctM family protein 4058702 5590047 EcE24377A_4075 Escherichia coli E24377A TRAP transporter DctM family protein YP_001465054.1 4057425 D 331111 CDS YP_001465055.1 157157642 5588362 4058715..4059701 1 NC_009801.1 identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787; TRAP transporter solute receptor DctP family protein 4059701 yiaO 5588362 yiaO Escherichia coli E24377A TRAP transporter solute receptor DctP family protein YP_001465055.1 4058715 D 331111 CDS YP_001465056.1 157159228 5588113 4059705..4061201 1 NC_009801.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; cryptic L-xylulose kinase 4061201 lyx 5588113 lyx Escherichia coli E24377A cryptic L-xylulose kinase YP_001465056.1 4059705 D 331111 CDS YP_001465057.1 157158725 5589768 4061198..4061860 1 NC_009801.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 4061860 sgbH 5589768 sgbH Escherichia coli E24377A 3-keto-L-gulonate-6-phosphate decarboxylase YP_001465057.1 4061198 D 331111 CDS YP_001465058.1 157154976 5586423 4061853..4062713 1 NC_009801.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 4062713 5586423 EcE24377A_4079 Escherichia coli E24377A L-xylulose 5-phosphate 3-epimerase YP_001465058.1 4061853 D 331111 CDS YP_001465059.1 157159253 5588694 4062707..4063402 1 NC_009801.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4063402 sgbE 5588694 sgbE Escherichia coli E24377A L-ribulose-5-phosphate 4-epimerase YP_001465059.1 4062707 D 331111 CDS YP_001465060.1 157155960 5590016 complement(4063749..4064489) 1 NC_009801.1 identified by match to protein family HMM PF06629; match to protein family HMM TIGR03304; MltA-interacting protein MipA 4064489 5590016 EcE24377A_4081 Escherichia coli E24377A MltA-interacting protein MipA YP_001465060.1 4063749 R 331111 CDS YP_001465061.1 157155429 5586579 4064613..4065587 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 4065587 5586579 EcE24377A_4083 Escherichia coli E24377A LysR family transcriptional regulator YP_001465061.1 4064613 D 331111 CDS YP_001465062.1 157156525 5590282 complement(4065584..4066720) 1 NC_009801.1 identified by match to protein family HMM PF00529; membrane fusion protein family protein 4066720 5590282 EcE24377A_4082 Escherichia coli E24377A membrane fusion protein family protein YP_001465062.1 4065584 R 331111 CDS YP_001465063.1 157157037 5590234 complement(4066726..4067049) 1 NC_009801.1 identified by similarity to GB:AAF95962.1; hypothetical protein 4067049 5590234 EcE24377A_4084 Escherichia coli E24377A hypothetical protein YP_001465063.1 4066726 R 331111 CDS YP_001465064.1 157158282 5589039 4067163..4067375 1 NC_009801.1 identified by glimmer; hypothetical protein 4067375 5589039 EcE24377A_4085 Escherichia coli E24377A hypothetical protein YP_001465064.1 4067163 D 331111 CDS YP_001465065.1 157159129 5589288 complement(4067594..4069132) 1 NC_009801.1 identified by similarity to SP:P37685; match to protein family HMM PF00171; aldehyde dehydrogenase 4069132 aldB 5589288 aldB Escherichia coli E24377A aldehyde dehydrogenase YP_001465065.1 4067594 R 331111 CDS YP_001465066.1 157154897 5590691 complement(4069297..4070448) 1 NC_009801.1 identified by match to protein family HMM PF00465; alcohol dehydrogenase 4070448 adhB 5590691 adhB Escherichia coli E24377A alcohol dehydrogenase YP_001465066.1 4069297 R 331111 CDS YP_001465067.1 157155659 5589628 complement(4070638..4072482) 1 NC_009801.1 identified by similarity to SP:P14081; match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM PF09106; match to protein family HMM PF09107; match to protein family HMM TIGR00475; selenocysteinyl-tRNA-specific translation factor 4072482 selB 5589628 selB Escherichia coli E24377A selenocysteinyl-tRNA-specific translation factor YP_001465067.1 4070638 R 331111 CDS YP_001465068.1 157156233 5588280 complement(4072479..4073870) 1 NC_009801.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 4073870 selA 5588280 selA Escherichia coli E24377A selenocysteine synthase YP_001465068.1 4072479 R 331111 CDS YP_001465069.1 157156960 5586688 complement(4073968..4074576) 1 NC_009801.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase 4074576 5586688 EcE24377A_4090 Escherichia coli E24377A glutathione S-transferase YP_001465069.1 4073968 R 331111 CDS YP_001465070.1 157157872 5587384 4074575..4074718 1 NC_009801.1 identified by glimmer; hypothetical protein 4074718 5587384 EcE24377A_4091 Escherichia coli E24377A hypothetical protein YP_001465070.1 4074575 D 331111 CDS YP_001465071.1 157156193 5588693 4074805..4079040 1 NC_009801.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; protein rhsB 4079040 5588693 EcE24377A_4092 Escherichia coli E24377A protein rhsB YP_001465071.1 4074805 D 331111 CDS YP_001465072.1 157158173 5588671 4079500..4080342 1 NC_009801.1 identified by match to protein family HMM PF03130; hypothetical protein 4080342 5588671 EcE24377A_4093 Escherichia coli E24377A hypothetical protein YP_001465072.1 4079500 D 331111 CDS YP_001465073.1 157156060 5588869 4080384..4081328 1 NC_009801.1 identified by match to protein family HMM PF03527; RHS domain-containing protein 4081328 5588869 EcE24377A_4094 Escherichia coli E24377A RHS domain-containing protein YP_001465073.1 4080384 D 331111 CDS YP_001465074.1 157156450 5586802 complement(4083405..4084541) 1 NC_009801.1 identified by match to protein family HMM PF00529; membrane fusion protein family protein 4084541 5586802 EcE24377A_4095 Escherichia coli E24377A membrane fusion protein family protein YP_001465074.1 4083405 R 331111 CDS YP_001465075.1 157157045 5588077 complement(4084544..4084906) 1 NC_009801.1 identified by similarity to GB:AAN82851.1; hypothetical protein 4084906 5588077 EcE24377A_4096 Escherichia coli E24377A hypothetical protein YP_001465075.1 4084544 R 331111 CDS YP_001465076.1 157155168 5588408 4084932..4085024 1 NC_009801.1 identified by glimmer; hypothetical protein 4085024 5588408 EcE24377A_4097 Escherichia coli E24377A hypothetical protein YP_001465076.1 4084932 D 331111 CDS YP_001465077.1 157155646 5590822 4085443..4087356 1 NC_009801.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851; PTS system mannitol-specific transporter subunit IIABC 4087356 mtlA 5590822 mtlA Escherichia coli E24377A PTS system mannitol-specific transporter subunit IIABC YP_001465077.1 4085443 D 331111 CDS YP_001465078.1 157158409 5588824 4087451..4088599 1 NC_009801.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol-1-phosphate 5-dehydrogenase 4088599 mtlD 5588824 mtlD Escherichia coli E24377A mannitol-1-phosphate 5-dehydrogenase YP_001465078.1 4087451 D 331111 CDS YP_001465079.1 157158948 5588936 4088599..4089186 1 NC_009801.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 4089186 mtlR 5588936 mtlR Escherichia coli E24377A mannitol repressor protein YP_001465079.1 4088599 D 331111 CDS YP_001465080.1 157157342 5587850 complement(4089198..4089407) 1 NC_009801.1 identified by similarity to RF:NP_462588.1; hypothetical protein 4089407 5587850 EcE24377A_4101 Escherichia coli E24377A hypothetical protein YP_001465080.1 4089198 R 331111 CDS YP_001465081.1 157157869 5586568 complement(4089608..4089985) 1 NC_009801.1 identified by glimmer; hypothetical protein 4089985 5586568 EcE24377A_4102 Escherichia coli E24377A hypothetical protein YP_001465081.1 4089608 R 331111 CDS YP_001465082.1 157156346 5586063 4089692..4090054 1 NC_009801.1 hypothetical protein 4090054 5586063 EcE24377A_4103 Escherichia coli E24377A hypothetical protein YP_001465082.1 4089692 D 331111 CDS YP_001465083.1 157156878 5590430 complement(4090140..4090232) 1 NC_009801.1 identified by glimmer; hypothetical protein 4090232 5590430 EcE24377A_4104 Escherichia coli E24377A hypothetical protein YP_001465083.1 4090140 R 331111 CDS YP_001465084.1 157156925 5586207 4090597..4091280 1 NC_009801.1 lipoprotein 4091280 5586207 EcE24377A_4105 Escherichia coli E24377A lipoprotein YP_001465084.1 4090597 D 331111 CDS YP_001465085.1 157157415 5589966 4091324..4096174 1 NC_009801.1 identified by match to protein family HMM PF03895; match to protein family HMM PF05658; match to protein family HMM PF05662; hemagglutinin/invasin protein 4096174 5589966 EcE24377A_4106 Escherichia coli E24377A hemagglutinin/invasin protein YP_001465085.1 4091324 D 331111 CDS YP_001465086.1 157157727 5588553 4096543..4098198 1 NC_009801.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795; L-lactate permease 4098198 lldP 5588553 lldP Escherichia coli E24377A L-lactate permease YP_001465086.1 4096543 D 331111 CDS YP_001465087.1 157158528 5590775 4098198..4098974 1 NC_009801.1 represses the lctPRD operon; DNA-binding transcriptional repressor LldR 4098974 5590775 EcE24377A_4108 Escherichia coli E24377A DNA-binding transcriptional repressor LldR YP_001465087.1 4098198 D 331111 CDS YP_001465088.1 157159353 5587517 4098971..4100161 1 NC_009801.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 4100161 lldD 5587517 lldD Escherichia coli E24377A L-lactate dehydrogenase YP_001465088.1 4098971 D 331111 CDS YP_001465089.1 157158942 5588456 4100347..4100820 1 NC_009801.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 4100820 5588456 EcE24377A_4110 Escherichia coli E24377A tRNA/rRNA methyltransferase YibK YP_001465089.1 4100347 D 331111 CDS YP_001465090.1 157155623 5588189 complement(4100873..4101694) 1 NC_009801.1 catalyzes the O-acetylation of serine; serine acetyltransferase 4101694 cysE 5588189 cysE Escherichia coli E24377A serine acetyltransferase YP_001465090.1 4100873 R 331111 CDS YP_001465091.1 157156422 5586380 complement(4101774..4102793) 1 NC_009801.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 4102793 gpsA 5586380 gpsA Escherichia coli E24377A NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_001465091.1 4101774 R 331111 CDS YP_001465092.1 157156442 5588019 complement(4102793..4103260) 1 NC_009801.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 4103260 secB 5588019 secB Escherichia coli E24377A preprotein translocase subunit SecB YP_001465092.1 4102793 R 331111 CDS YP_001465093.1 157157038 5590296 complement(4103323..4103574) 1 NC_009801.1 identified by similarity to SP:P0AC62; match to protein family HMM PF00462; match to protein family HMM TIGR02181; glutaredoxin 3 4103574 grxC 5590296 grxC Escherichia coli E24377A glutaredoxin 3 YP_001465093.1 4103323 R 331111 CDS YP_001465094.1 157155152 5589040 complement(4103716..4104147) 1 NC_009801.1 identified by match to protein family HMM PF00581; rhodanese domain-containing protein 4104147 5589040 EcE24377A_4115 Escherichia coli E24377A rhodanese domain-containing protein YP_001465094.1 4103716 R 331111 CDS YP_001465095.1 157155712 5589900 4104392..4105936 1 NC_009801.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 4105936 gpmI 5589900 gpmI Escherichia coli E24377A phosphoglyceromutase YP_001465095.1 4104392 D 331111 CDS YP_001465096.2 229220660 5588453 4105946..4107229 1 NC_009801.1 identified by match to protein family HMM PF01551; hypothetical protein 4107229 5588453 EcE24377A_4117 Escherichia coli E24377A hypothetical protein YP_001465096.2 4105946 D 331111 CDS YP_001465097.1 157157521 5586264 4107233..4108192 1 NC_009801.1 identified by match to protein family HMM PF04748; polysaccharide deacetylase 4108192 5586264 EcE24377A_4119 Escherichia coli E24377A polysaccharide deacetylase YP_001465097.1 4107233 D 331111 CDS YP_001465098.1 157158485 5589764 complement(4108179..4109213) 1 NC_009801.1 identified by match to protein family HMM PF00535; glycosyl transferase family protein 4109213 5589764 EcE24377A_4118 Escherichia coli E24377A glycosyl transferase family protein YP_001465098.1 4108179 R 331111 CDS YP_001465099.1 157157199 5590371 complement(4109452..4110477) 1 NC_009801.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 4110477 tdh 5590371 tdh Escherichia coli E24377A L-threonine 3-dehydrogenase YP_001465099.1 4109452 R 331111 CDS YP_001465100.1 157157713 5587002 complement(4110487..4111683) 1 NC_009801.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase 4111683 kbl 5587002 kbl Escherichia coli E24377A 2-amino-3-ketobutyrate CoA ligase YP_001465100.1 4110487 R 331111 CDS YP_001465101.1 157156802 5589144 4111897..4112829 1 NC_009801.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 4112829 rfaD 5589144 rfaD Escherichia coli E24377A ADP-L-glycero-D-manno-heptose-6-epimerase YP_001465101.1 4111897 D 331111 CDS YP_001465102.1 157156092 5587716 4112839..4113885 1 NC_009801.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 4113885 rfaF 5587716 rfaF Escherichia coli E24377A ADP-heptose--LPS heptosyltransferase YP_001465102.1 4112839 D 331111 CDS YP_001465103.1 157156913 5586038 4113889..4114860 1 NC_009801.1 identified by match to protein family HMM PF01075; match to protein family HMM TIGR02193; ADP-heptose--LPS heptosyltransferase 4114860 rfaC 5586038 rfaC Escherichia coli E24377A ADP-heptose--LPS heptosyltransferase YP_001465103.1 4113889 D 331111 CDS YP_001465104.1 157156511 5589715 complement(4114930..4116183) 1 NC_009801.1 identified by match to protein family HMM PF04932; O-antigen polymerase 4116183 5589715 EcE24377A_4125 Escherichia coli E24377A O-antigen polymerase YP_001465104.1 4114930 R 331111 CDS YP_001465105.1 157155796 5588064 complement(4116229..4117212) 1 NC_009801.1 identified by match to protein family HMM PF00535; glycosyl transferase family protein 4117212 5588064 EcE24377A_4126 Escherichia coli E24377A glycosyl transferase family protein YP_001465105.1 4116229 R 331111 CDS YP_001465106.1 157155439 5588286 complement(4117297..4118322) 1 NC_009801.1 identified by similarity to GB:AAC69673.1; match to protein family HMM PF01501; match to protein family HMM PF08437; lipopolysaccharide 1,2-galactosyltransferase 4118322 waaW 5588286 waaW Escherichia coli E24377A lipopolysaccharide 1,2-galactosyltransferase YP_001465106.1 4117297 R 331111 CDS YP_001465107.1 157155314 5588631 complement(4118348..4119040) 1 NC_009801.1 identified by similarity to SP:P27240; match to protein family HMM PF06176; lipopolysaccharide core biosynthesis protein 4119040 rfaY 5588631 rfaY Escherichia coli E24377A lipopolysaccharide core biosynthesis protein YP_001465107.1 4118348 R 331111 CDS YP_001465108.1 157154988 5586431 complement(4119050..4120045) 1 NC_009801.1 identified by similarity to SP:P27129; match to protein family HMM PF01501; match to protein family HMM PF08437; lipopolysaccharide 1,2-glucosyltransferase 4120045 rfaJ 5586431 rfaJ Escherichia coli E24377A lipopolysaccharide 1,2-glucosyltransferase YP_001465108.1 4119050 R 331111 CDS YP_001465109.1 157159286 5586429 complement(4120062..4121078) 1 NC_009801.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08437; lipopolysaccharide 1,3-galactosyltransferase 4121078 rfaI 5586429 rfaI Escherichia coli E24377A lipopolysaccharide 1,3-galactosyltransferase YP_001465109.1 4120062 R 331111 CDS YP_001465110.1 157158623 5588171 complement(4121094..4121891) 1 NC_009801.1 identified by match to protein family HMM PF06293; lipopolysaccharide core biosynthesis protein RfaP 4121891 rfaP 5588171 rfaP Escherichia coli E24377A lipopolysaccharide core biosynthesis protein RfaP YP_001465110.1 4121094 R 331111 CDS YP_001465111.1 157157470 5586225 complement(4121884..4123008) 1 NC_009801.1 identified by similarity to SP:P25740; match to protein family HMM PF00534; lipopolysaccharide core biosynthesis protein RfaG 4123008 rfaG 5586225 rfaG Escherichia coli E24377A lipopolysaccharide core biosynthesis protein RfaG YP_001465111.1 4121884 R 331111 CDS YP_001465112.1 157157104 5590050 complement(4123005..4124027) 1 NC_009801.1 identified by similarity to SP:P25742; match to protein family HMM PF01075; match to protein family HMM TIGR02201; lipopolysaccharide core biosynthesis protein 4124027 rfaQ 5590050 rfaQ Escherichia coli E24377A lipopolysaccharide core biosynthesis protein YP_001465112.1 4123005 R 331111 CDS YP_001465113.1 157157302 5586758 4124476..4125753 1 NC_009801.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4125753 waaA 5586758 waaA Escherichia coli E24377A 3-deoxy-D-manno-octulosonic-acid transferase YP_001465113.1 4124476 D 331111 CDS YP_001465114.1 157158987 5590301 4125761..4126240 1 NC_009801.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4126240 coaD 5590301 coaD Escherichia coli E24377A phosphopantetheine adenylyltransferase YP_001465114.1 4125761 D 331111 CDS YP_001465115.1 157158292 5588210 complement(4126279..4127088) 1 NC_009801.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 4127088 mutM 5588210 mutM Escherichia coli E24377A formamidopyrimidine-DNA glycosylase YP_001465115.1 4126279 R 331111 CDS YP_001465116.1 157155857 5589536 complement(4127186..4127353) 1 NC_009801.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 4127353 rpmG 5589536 rpmG Escherichia coli E24377A 50S ribosomal protein L33 YP_001465116.1 4127186 R 331111 CDS YP_001465117.1 157155847 5588436 complement(4127374..4127610) 1 NC_009801.1 required for 70S ribosome assembly; 50S ribosomal protein L28 4127610 rpmB 5588436 rpmB Escherichia coli E24377A 50S ribosomal protein L28 YP_001465117.1 4127374 R 331111 CDS YP_001465118.1 157155076 5590288 complement(4127827..4128495) 1 NC_009801.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 4128495 radC 5590288 radC Escherichia coli E24377A DNA repair protein RadC YP_001465118.1 4127827 R 331111 CDS YP_001465119.1 157156838 5587737 4128667..4129887 1 NC_009801.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4129887 coaBC 5587737 coaBC Escherichia coli E24377A bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_001465119.1 4128667 D 331111 CDS YP_001465120.1 157157952 5586080 4129868..4130323 1 NC_009801.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4130323 dut 5586080 dut Escherichia coli E24377A deoxyuridine 5'-triphosphate nucleotidohydrolase YP_001465120.1 4129868 D 331111 CDS YP_001465121.1 157157966 5588015 4130430..4131026 1 NC_009801.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4131026 slmA 5588015 slmA Escherichia coli E24377A nucleoid occlusion protein YP_001465121.1 4130430 D 331111 CDS YP_001465122.1 157157293 5589603 complement(4131063..4131704) 1 NC_009801.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 4131704 pyrE 5589603 pyrE Escherichia coli E24377A orotate phosphoribosyltransferase YP_001465122.1 4131063 R 331111 CDS YP_001465123.1 157158506 5589981 complement(4131770..4132486) 1 NC_009801.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 4132486 rph 5589981 rph Escherichia coli E24377A ribonuclease PH YP_001465123.1 4131770 R 331111 CDS YP_001465124.1 157155093 5589558 4132613..4133476 1 NC_009801.1 identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255; hypothetical protein 4133476 5589558 EcE24377A_4145 Escherichia coli E24377A hypothetical protein YP_001465124.1 4132613 D 331111 CDS YP_001465125.1 157157093 5588688 complement(4133493..4133633) 1 NC_009801.1 identified by glimmer; hypothetical protein 4133633 5588688 EcE24377A_4146 Escherichia coli E24377A hypothetical protein YP_001465125.1 4133493 R 331111 CDS YP_001465126.1 157157859 5586843 4133697..4134521 1 NC_009801.1 identified by similarity to SP:P23840; DNA-damage-inducible protein D 4134521 dinD 5586843 dinD Escherichia coli E24377A DNA-damage-inducible protein D YP_001465126.1 4133697 D 331111 CDS YP_001465127.1 157157348 5589413 4134813..4135430 1 NC_009801.1 identified by match to protein family HMM PF03458; hypothetical protein 4135430 5589413 EcE24377A_4149 Escherichia coli E24377A hypothetical protein YP_001465127.1 4134813 D 331111 CDS YP_001465128.1 157158891 5589251 complement(4135427..4137115) 1 NC_009801.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB 4137115 ligB 5589251 ligB Escherichia coli E24377A NAD-dependent DNA ligase LigB YP_001465128.1 4135427 R 331111 CDS YP_001465129.1 157158438 5586292 4137367..4137990 1 NC_009801.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4137990 gmk 5586292 gmk Escherichia coli E24377A guanylate kinase YP_001465129.1 4137367 D 331111 CDS YP_001465130.1 157155218 5590309 4138045..4138320 1 NC_009801.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4138320 rpoZ 5590309 rpoZ Escherichia coli E24377A DNA-directed RNA polymerase subunit omega YP_001465130.1 4138045 D 331111 CDS YP_001465131.1 157156870 5586755 4138339..4140447 1 NC_009801.1 identified by similarity to SP:P17580; match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4140447 spoT 5586755 spoT Escherichia coli E24377A bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase YP_001465131.1 4138339 D 331111 CDS YP_001465132.1 157156957 5586829 4140454..4141143 1 NC_009801.1 specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4141143 trmH 5586829 trmH Escherichia coli E24377A tRNA guanosine-2'-O-methyltransferase YP_001465132.1 4140454 D 331111 CDS YP_001465133.1 157155919 5590655 4141149..4143230 1 NC_009801.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4143230 recG 5590655 recG Escherichia coli E24377A ATP-dependent DNA helicase RecG YP_001465133.1 4141149 D 331111 CDS YP_001465134.1 157155212 5587389 complement(4143215..4144081) 1 NC_009801.1 identified by similarity to GB:AAG58797.1; hypothetical protein 4144081 5587389 EcE24377A_4155 Escherichia coli E24377A hypothetical protein YP_001465134.1 4143215 R 331111 CDS YP_001465135.1 157155900 5587149 complement(4144084..4145289) 1 NC_009801.1 identified by similarity to SP:P0AER8; match to protein family HMM PF03616; match to protein family HMM TIGR00210; sodium/glutamate symporter 4145289 gltS 5587149 gltS Escherichia coli E24377A sodium/glutamate symporter YP_001465135.1 4144084 R 331111 CDS YP_001465136.1 157158354 5590394 4145569..4146960 1 NC_009801.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; xanthine permease 4146960 yicE 5590394 yicE Escherichia coli E24377A xanthine permease YP_001465136.1 4145569 D 331111 CDS YP_001465137.1 157159023 5587366 4147081..4148790 1 NC_009801.1 identified by match to protein family HMM PF05170; AsmA family protein 4148790 5587366 EcE24377A_4159 Escherichia coli E24377A AsmA family protein YP_001465137.1 4147081 D 331111 CDS YP_001465138.1 157157323 5588392 complement(4148843..4151161) 1 NC_009801.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase 4151161 yicI 5588392 yicI Escherichia coli E24377A alpha-xylosidase YP_001465138.1 4148843 R 331111 CDS YP_001465139.1 157157917 5589578 4151129..4151269 1 NC_009801.1 identified by glimmer; hypothetical protein 4151269 5589578 EcE24377A_4162 Escherichia coli E24377A hypothetical protein YP_001465139.1 4151129 D 331111 CDS YP_001465140.1 157157276 5590473 complement(4151171..4152610) 1 NC_009801.1 may be involved in the transport of galactosides-pentoses-hexuronides; transporter 4152610 5590473 EcE24377A_4161 Escherichia coli E24377A transporter YP_001465140.1 4151171 R 331111 CDS YP_001465141.1 157159308 5586501 4153479..4153613 1 NC_009801.1 identified by glimmer; hypothetical protein 4153613 5586501 EcE24377A_4165 Escherichia coli E24377A hypothetical protein YP_001465141.1 4153479 D 331111 CDS YP_001465142.1 157154878 5588998 4153576..4154760 1 NC_009801.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00899; sugar efflux transporter C 4154760 setC 5588998 setC Escherichia coli E24377A sugar efflux transporter C YP_001465142.1 4153576 D 331111 CDS YP_001465143.1 157155559 5587840 4154871..4155794 1 NC_009801.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950; carboxylate/amino acid/amine transporter 4155794 5587840 EcE24377A_4167 Escherichia coli E24377A carboxylate/amino acid/amine transporter YP_001465143.1 4154871 D 331111 CDS YP_001465144.1 157155413 5589053 complement(4155798..4156616) 1 NC_009801.1 identified by similarity to SP:P04846; match to protein family HMM PF03180; match to protein family HMM TIGR00363; hypothetical protein 4156616 nlpA 5589053 nlpA Escherichia coli E24377A hypothetical protein YP_001465144.1 4155798 R 331111 CDS YP_001465145.1 157156083 5590593 4156838..4157131 1 NC_009801.1 identified by similarity to SP:Q5PC60; hypothetical protein 4157131 5590593 EcE24377A_4169 Escherichia coli E24377A hypothetical protein YP_001465145.1 4156838 D 331111 CDS YP_001465146.1 157157594 5589851 complement(4157172..4158527) 1 NC_009801.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter 4158527 nepI 5589851 nepI Escherichia coli E24377A ribonucleoside transporter YP_001465146.1 4157172 R 331111 CDS YP_001465147.1 157157145 5590215 complement(4158573..4159025) 1 NC_009801.1 identified by match to protein family HMM PF06711; hypothetical protein 4159025 5590215 EcE24377A_4171 Escherichia coli E24377A hypothetical protein YP_001465147.1 4158573 R 331111 CDS YP_001465148.1 157158084 5589637 complement(4159078..4160490) 1 NC_009801.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; sulfate permease inorganic anion transporter 4160490 5589637 EcE24377A_4172 Escherichia coli E24377A sulfate permease inorganic anion transporter YP_001465148.1 4159078 R 331111 CDS YP_001465149.1 157158837 5587057 4160587..4162353 1 NC_009801.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4162353 ade 5587057 ade Escherichia coli E24377A cryptic adenine deaminase YP_001465149.1 4160587 D 331111 CDS YP_001465150.1 157159158 5588881 complement(4162398..4163789) 1 NC_009801.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 4163789 uhpT 5588881 uhpT Escherichia coli E24377A sugar phosphate antiporter YP_001465150.1 4162398 R 331111 CDS YP_001465151.1 157155233 5588544 complement(4163927..4165246) 1 NC_009801.1 membrane protein regulates uhpT expression; regulatory protein UhpC 4165246 uhpC 5588544 uhpC Escherichia coli E24377A regulatory protein UhpC YP_001465151.1 4163927 R 331111 CDS YP_001465152.1 157156876 5589042 complement(4165256..4166749) 1 NC_009801.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB 4166749 uhpB 5589042 uhpB Escherichia coli E24377A sensory histidine kinase UhpB YP_001465152.1 4165256 R 331111 CDS YP_001465153.1 157156342 5588125 complement(4166658..4166771) 1 NC_009801.1 identified by glimmer; hypothetical protein 4166771 5588125 EcE24377A_4177 Escherichia coli E24377A hypothetical protein YP_001465153.1 4166658 R 331111 CDS YP_001465154.1 157156118 5586219 complement(4166758..4167348) 1 NC_009801.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA 4167348 uhpA 5586219 uhpA Escherichia coli E24377A DNA-binding transcriptional activator UhpA YP_001465154.1 4166758 R 331111 CDS YP_001465155.1 157157982 5587810 complement(4167422..4167712) 1 NC_009801.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit 4167712 ilvN 5587810 ilvN Escherichia coli E24377A acetolactate synthase 1 regulatory subunit YP_001465155.1 4167422 R 331111 CDS YP_001465156.1 157157654 5588193 complement(4167716..4169404) 1 NC_009801.1 identified by similarity to SP:P08142; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118; acetolactate synthase catalytic subunit 4169404 ilvB 5588193 ilvB Escherichia coli E24377A acetolactate synthase catalytic subunit YP_001465156.1 4167716 R 331111 CDS YP_001465157.1 157158889 5590054 4170681..4171865 1 NC_009801.1 multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4171865 emrD 5590054 emrD Escherichia coli E24377A multidrug resistance protein D YP_001465157.1 4170681 D 331111 CDS YP_001465158.1 157158721 5586290 complement(4171873..4172370) 1 NC_009801.1 hypothetical protein 4172370 5586290 EcE24377A_4182 Escherichia coli E24377A hypothetical protein YP_001465158.1 4171873 R 331111 CDS YP_001465159.1 157155834 5588520 complement(4172367..4172729) 1 NC_009801.1 hypothetical protein 4172729 5588520 EcE24377A_4183 Escherichia coli E24377A hypothetical protein YP_001465159.1 4172367 R 331111 CDS YP_001465160.1 157155480 5588413 complement(4172719..4173066) 1 NC_009801.1 identified by match to protein family HMM PF02656; hypothetical protein 4173066 5588413 EcE24377A_4184 Escherichia coli E24377A hypothetical protein YP_001465160.1 4172719 R 331111 CDS YP_001465161.1 157157962 5586787 4173176..4173625 1 NC_009801.1 identified by similarity to SP:P31446; hypothetical protein 4173625 5586787 EcE24377A_4185 Escherichia coli E24377A hypothetical protein YP_001465161.1 4173176 D 331111 CDS YP_001465162.1 157157618 5590158 complement(4173672..4175165) 1 NC_009801.1 identified by match to protein family HMM PF00884; sulfatase 4175165 5590158 EcE24377A_4186 Escherichia coli E24377A sulfatase YP_001465162.1 4173672 R 331111 CDS YP_001465163.1 157159014 5590129 complement(4175162..4176877) 1 NC_009801.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK 4176877 5590129 EcE24377A_4187 Escherichia coli E24377A symporter YidK YP_001465163.1 4175162 R 331111 CDS YP_001465164.1 157155026 5588211 4177044..4177937 1 NC_009801.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 4177937 5588211 EcE24377A_4189 Escherichia coli E24377A AraC family transcriptional regulator YP_001465164.1 4177044 D 331111 CDS YP_001465165.1 157157824 5588151 complement(4178748..4180625) 1 NC_009801.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00852; match to protein family HMM TIGR02005; PTS system, alpha-glucoside-specific transporter subunit IIBC 4180625 5588151 EcE24377A_4190 Escherichia coli E24377A PTS system, alpha-glucoside-specific transporter subunit IIBC YP_001465165.1 4178748 R 331111 CDS YP_001465166.1 157157178 5589076 4180660..4181376 1 NC_009801.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 4181376 5589076 EcE24377A_4192 Escherichia coli E24377A GntR family transcriptional regulator YP_001465166.1 4180660 D 331111 CDS YP_001465167.1 157159179 5587290 complement(4181373..4183034) 1 NC_009801.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625; hypothetical protein 4183034 5587290 EcE24377A_4191 Escherichia coli E24377A hypothetical protein YP_001465167.1 4181373 R 331111 CDS YP_001465168.1 157159428 5590351 4183065..4183226 1 NC_009801.1 identified by glimmer; hypothetical protein 4183226 5590351 EcE24377A_4193 Escherichia coli E24377A hypothetical protein YP_001465168.1 4183065 D 331111 CDS YP_001465169.1 157157574 5586090 complement(4183231..4183659) 1 NC_009801.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB 4183659 ibpB 5586090 ibpB Escherichia coli E24377A heat shock chaperone IbpB YP_001465169.1 4183231 R 331111 CDS YP_001465170.1 157155984 5587526 complement(4183771..4184184) 1 NC_009801.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA 4184184 ibpA 5587526 ibpA Escherichia coli E24377A heat shock protein IbpA YP_001465170.1 4183771 R 331111 CDS YP_001465171.1 157155591 5588584 complement(4184383..4184475) 1 NC_009801.1 identified by glimmer; hypothetical protein 4184475 5588584 EcE24377A_4196 Escherichia coli E24377A hypothetical protein YP_001465171.1 4184383 R 331111 CDS YP_001465172.1 157158540 5590817 4184415..4184822 1 NC_009801.1 identified by match to protein family HMM PF07119; hypothetical protein 4184822 5590817 EcE24377A_4197 Escherichia coli E24377A hypothetical protein YP_001465172.1 4184415 D 331111 CDS YP_001465173.1 157158706 5587855 complement(4184824..4186038) 1 NC_009801.1 identified by similarity to GB:ABB64081.1; hypothetical protein 4186038 5587855 EcE24377A_4198 Escherichia coli E24377A hypothetical protein YP_001465173.1 4184824 R 331111 CDS YP_001465174.1 157159239 5590811 4186139..4187203 1 NC_009801.1 FAD/NAD(P)-binding domain; oxidoreductase 4187203 5590811 EcE24377A_4200 Escherichia coli E24377A oxidoreductase YP_001465174.1 4186139 D 331111 CDS YP_001465175.1 157157668 5586560 complement(4187200..4188537) 1 NC_009801.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00881; match to protein family HMM TIGR00893; d-galactonate transporter 4188537 5586560 EcE24377A_4199 Escherichia coli E24377A d-galactonate transporter YP_001465175.1 4187200 R 331111 CDS YP_001465176.1 157158203 5588263 complement(4188612..4189760) 1 NC_009801.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746; galactonate dehydratase 4189760 5588263 EcE24377A_4201 Escherichia coli E24377A galactonate dehydratase YP_001465176.1 4188612 R 331111 CDS YP_001465177.1 157156056 5589400 complement(4189757..4190374) 1 NC_009801.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 4190374 5589400 EcE24377A_4202 Escherichia coli E24377A 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_001465177.1 4189757 R 331111 CDS YP_001465178.1 157158999 5587555 complement(4190358..4191236) 1 NC_009801.1 identified by match to protein family HMM PF05035; 2-dehydro-3-deoxygalactonokinase 4191236 dgoK 5587555 dgoK Escherichia coli E24377A 2-dehydro-3-deoxygalactonokinase YP_001465178.1 4190358 R 331111 CDS YP_001465179.1 157157269 5587248 complement(4191233..4191922) 1 NC_009801.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; galactonate operon transcriptional repressor 4191922 dgoR 5587248 dgoR Escherichia coli E24377A galactonate operon transcriptional repressor YP_001465179.1 4191233 R 331111 CDS YP_001465180.1 157157741 5590517 4192095..4192856 1 NC_009801.1 hypothetical protein 4192856 5590517 EcE24377A_4205 Escherichia coli E24377A hypothetical protein YP_001465180.1 4192095 D 331111 CDS YP_001465181.1 157157907 5590202 complement(4192902..4193714) 1 NC_009801.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase 4193714 yidA 5590202 yidA Escherichia coli E24377A sugar phosphatase YP_001465181.1 4192902 R 331111 CDS YP_001465182.1 157156966 5588024 complement(4193829..4194227) 1 NC_009801.1 yidB; identified by match to protein family HMM PF06078; hypothetical protein 4194227 5588024 EcE24377A_4207 Escherichia coli E24377A hypothetical protein YP_001465182.1 4193829 R 331111 CDS YP_001465183.1 157155028 5586701 4194360..4194461 1 NC_009801.1 identified by glimmer; hypothetical protein 4194461 5586701 EcE24377A_4208 Escherichia coli E24377A hypothetical protein YP_001465183.1 4194360 D 331111 CDS YP_001465184.1 157155879 5589170 complement(4194467..4196881) 1 NC_009801.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 4196881 gyrB 5589170 gyrB Escherichia coli E24377A DNA gyrase subunit B YP_001465184.1 4194467 R 331111 CDS YP_001465185.1 157155989 5590164 complement(4196910..4197983) 1 NC_009801.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4197983 recF 5590164 recF Escherichia coli E24377A recombination protein F YP_001465185.1 4196910 R 331111 CDS YP_001465186.1 157156673 5589967 complement(4197983..4199083) 1 NC_009801.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 4199083 dnaN 5589967 dnaN Escherichia coli E24377A DNA polymerase III subunit beta YP_001465186.1 4197983 R 331111 CDS YP_001465187.1 157155055 5590505 complement(4199088..4200491) 1 NC_009801.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 4200491 dnaA 5590505 dnaA Escherichia coli E24377A chromosomal replication initiation protein YP_001465187.1 4199088 R 331111 CDS YP_001465188.1 157157421 5586371 4201098..4201238 1 NC_009801.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4201238 rpmH 5586371 rpmH Escherichia coli E24377A 50S ribosomal protein L34 YP_001465188.1 4201098 D 331111 CDS YP_001465189.1 157156562 5588609 4201255..4201614 1 NC_009801.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4201614 rnpA 5588609 rnpA Escherichia coli E24377A ribonuclease P YP_001465189.1 4201255 D 331111 CDS YP_001465190.1 157156055 5588964 4201838..4203484 1 NC_009801.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4203484 5588964 EcE24377A_4215 Escherichia coli E24377A inner membrane protein translocase component YidC YP_001465190.1 4201838 D 331111 CDS YP_001465191.1 157155417 5588223 4203590..4204954 1 NC_009801.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4204954 trmE 5588223 trmE Escherichia coli E24377A tRNA modification GTPase TrmE YP_001465191.1 4203590 D 331111 CDS YP_001465192.1 157155675 5587073 4205492..4206907 1 NC_009801.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4206907 tnaA 5587073 tnaA Escherichia coli E24377A tryptophanase YP_001465192.1 4205492 D 331111 CDS YP_001465193.1 157158998 5586347 4206998..4208245 1 NC_009801.1 tryptophan transporter of low affinity; tryptophan permease TnaB 4208245 tnaB 5586347 tnaB Escherichia coli E24377A tryptophan permease TnaB YP_001465193.1 4206998 D 331111 CDS YP_001465194.1 157159363 5587247 4208377..4209552 1 NC_009801.1 Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4209552 mdtL 5587247 mdtL Escherichia coli E24377A multidrug efflux system protein MdtL YP_001465194.1 4208377 D 331111 CDS YP_001465195.1 157157265 5587986 4209527..4210486 1 NC_009801.1 Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4210486 5587986 EcE24377A_4220 Escherichia coli E24377A DNA-binding transcriptional regulator YidZ YP_001465195.1 4209527 D 331111 CDS YP_001465196.1 157156582 5588368 4210643..4211392 1 NC_009801.1 identified by similarity to GB:AAP19005.1; hypothetical protein 4211392 5588368 EcE24377A_4221 Escherichia coli E24377A hypothetical protein YP_001465196.1 4210643 D 331111 CDS YP_001465197.1 157156262 5587701 4211414..4211980 1 NC_009801.1 identified by match to protein family HMM PF03358; NADPH-dependent FMN reductase 4211980 5587701 EcE24377A_4222 Escherichia coli E24377A NADPH-dependent FMN reductase YP_001465197.1 4211414 D 331111 CDS YP_001465198.1 157156784 5588577 complement(4212034..4213371) 1 NC_009801.1 identified by match to protein family HMM PF00860; sulfate permease inorganic anion transporter 4213371 5588577 EcE24377A_4223 Escherichia coli E24377A sulfate permease inorganic anion transporter YP_001465198.1 4212034 R 331111 CDS YP_001465199.1 157154762 5587065 4213538..4214203 1 NC_009801.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4214203 yieH 5587065 yieH Escherichia coli E24377A 6-phosphogluconate phosphatase YP_001465199.1 4213538 D 331111 CDS YP_001465200.1 157155421 5587913 4214270..4214743 1 NC_009801.1 might be involved in hypersensitivity to nitrofurzone; inner membrane protein 4214743 5587913 EcE24377A_4225 Escherichia coli E24377A inner membrane protein YP_001465200.1 4214270 D 331111 CDS YP_001465201.1 157155247 5590464 4214792..4215379 1 NC_009801.1 identified by similarity to SP:P31469; match to protein family HMM PF03691; hypothetical protein 4215379 5590464 EcE24377A_4226 Escherichia coli E24377A hypothetical protein YP_001465201.1 4214792 D 331111 CDS YP_001465202.1 157155622 5585907 complement(4215441..4216163) 1 NC_009801.1 identified by match to protein family HMM PF01182; 6-phosphogluconolactonase 4216163 5585907 EcE24377A_4227 Escherichia coli E24377A 6-phosphogluconolactonase YP_001465202.1 4215441 R 331111 CDS YP_001465203.1 157158571 5586379 complement(4216178..4217272) 1 NC_009801.1 identified by match to protein family HMM PF00756; match to protein family HMM PF02922; esterase 4217272 5586379 EcE24377A_4228 Escherichia coli E24377A esterase YP_001465203.1 4216178 R 331111 CDS YP_001465204.1 157159088 5586912 complement(4217374..4218990) 1 NC_009801.1 identified by similarity to SP:P26218; match to protein family HMM PF02264; glucoside specific outer membrane porin BglH 4218990 bglH 5586912 bglH Escherichia coli E24377A glucoside specific outer membrane porin BglH YP_001465204.1 4217374 R 331111 CDS YP_001465205.1 157156633 5590178 complement(4219076..4220470) 1 NC_009801.1 identified by match to protein family HMM PF00232; 6-phospho-beta-glucosidase 4220470 5590178 EcE24377A_4230 Escherichia coli E24377A 6-phospho-beta-glucosidase YP_001465205.1 4219076 R 331111 CDS YP_001465206.1 157157352 5586356 complement(4220489..4222366) 1 NC_009801.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunit IIABC 4222366 bglF 5586356 bglF Escherichia coli E24377A PTS system beta-glucoside-specific transporter subunit IIABC YP_001465206.1 4220489 R 331111 CDS YP_001465207.1 157156483 5589366 4221600..4221731 1 NC_009801.1 identified by glimmer; hypothetical protein 4221731 5589366 EcE24377A_4232 Escherichia coli E24377A hypothetical protein YP_001465207.1 4221600 D 331111 CDS YP_001465208.1 157156505 5589621 complement(4222500..4223336) 1 NC_009801.1 positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG 4223336 5589621 EcE24377A_4233 Escherichia coli E24377A transcriptional antiterminator BglG YP_001465208.1 4222500 R 331111 CDS YP_001465209.1 157159406 5588140 4223402..4223524 1 NC_009801.1 identified by glimmer; hypothetical protein 4223524 5588140 EcE24377A_4234 Escherichia coli E24377A hypothetical protein YP_001465209.1 4223402 D 331111 CDS YP_001465210.1 157154736 5588486 complement(4223622..4224347) 1 NC_009801.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 4224347 phoU 5588486 phoU Escherichia coli E24377A transcriptional regulator PhoU YP_001465210.1 4223622 R 331111 CDS YP_001465211.1 157158358 5590447 complement(4224362..4225135) 1 NC_009801.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 4225135 pstB 5590447 pstB Escherichia coli E24377A phosphate transporter ATP-binding protein YP_001465211.1 4224362 R 331111 CDS YP_001465212.1 157158078 5586936 complement(4225226..4226116) 1 NC_009801.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA 4226116 pstA 5586936 pstA Escherichia coli E24377A phosphate transporter permease subunit PtsA YP_001465212.1 4225226 R 331111 CDS YP_001465213.1 157155713 5590578 complement(4226116..4227075) 1 NC_009801.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC 4227075 pstC 5590578 pstC Escherichia coli E24377A phosphate transporter permease subunit PstC YP_001465213.1 4226116 R 331111 CDS YP_001465214.1 157156796 5588454 complement(4227162..4228202) 1 NC_009801.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00975; phosphate ABC transporter substrate-binding protein 4228202 pstS 5588454 pstS Escherichia coli E24377A phosphate ABC transporter substrate-binding protein YP_001465214.1 4227162 R 331111 CDS YP_001465215.1 157154757 5588311 complement(4228450..4229523) 1 NC_009801.1 identified by match to protein family HMM PF00419; fimbrial family protein 4229523 5588311 EcE24377A_4240 Escherichia coli E24377A fimbrial family protein YP_001465215.1 4228450 R 331111 CDS YP_001465216.1 157158761 5587626 complement(4229534..4232053) 1 NC_009801.1 identified by similarity to SP:P30130; match to protein family HMM PF00577; outer membrane usher protein FimD 4232053 fimD1 5587626 fimD1 Escherichia coli E24377A outer membrane usher protein FimD YP_001465216.1 4229534 R 331111 CDS YP_001465217.1 157155800 5590800 complement(4232081..4232812) 1 NC_009801.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753; pili assembly chaperone protein 4232812 5590800 EcE24377A_4242 Escherichia coli E24377A pili assembly chaperone protein YP_001465217.1 4232081 R 331111 CDS YP_001465218.1 157157463 5587515 complement(4232860..4233432) 1 NC_009801.1 identified by match to protein family HMM PF00419; fimbrial protein 4233432 5587515 EcE24377A_4243 Escherichia coli E24377A fimbrial protein YP_001465218.1 4232860 R 331111 CDS YP_001465219.1 157158587 5586069 complement(4233734..4235563) 1 NC_009801.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 4235563 glmS 5586069 glmS Escherichia coli E24377A glucosamine--fructose-6-phosphate aminotransferase YP_001465219.1 4233734 R 331111 CDS YP_001465220.1 157157902 5586055 complement(4235725..4237095) 1 NC_009801.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 4237095 glmU 5586055 glmU Escherichia coli E24377A bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_001465220.1 4235725 R 331111 CDS YP_001465221.1 157157090 5587570 4237365..4237889 1 NC_009801.1 identified by glimmer; hypothetical protein 4237889 5587570 EcE24377A_4248 Escherichia coli E24377A hypothetical protein YP_001465221.1 4237365 D 331111 CDS YP_001465222.1 157157156 5587812 complement(4237446..4237865) 1 NC_009801.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 4237865 atpC 5587812 atpC Escherichia coli E24377A ATP synthase F0F1 subunit epsilon YP_001465222.1 4237446 R 331111 CDS YP_001465223.1 157156404 5588798 complement(4237886..4239268) 1 NC_009801.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 4239268 atpD 5588798 atpD Escherichia coli E24377A ATP synthase F0F1 subunit beta YP_001465223.1 4237886 R 331111 CDS YP_001465224.1 157155717 5586118 complement(4239295..4240158) 1 NC_009801.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 4240158 atpG 5586118 atpG Escherichia coli E24377A ATP synthase F0F1 subunit gamma YP_001465224.1 4239295 R 331111 CDS YP_001465225.1 157155061 5588038 complement(4240209..4241750) 1 NC_009801.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 4241750 atpA 5588038 atpA Escherichia coli E24377A ATP synthase F0F1 subunit alpha YP_001465225.1 4240209 R 331111 CDS YP_001465226.1 157158846 5586867 complement(4241763..4242296) 1 NC_009801.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 4242296 atpH 5586867 atpH Escherichia coli E24377A ATP synthase F0F1 subunit delta YP_001465226.1 4241763 R 331111 CDS YP_001465227.1 157156607 5589230 complement(4242311..4242781) 1 NC_009801.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 4242781 atpF 5589230 atpF Escherichia coli E24377A ATP synthase F0F1 subunit B YP_001465227.1 4242311 R 331111 CDS YP_001465228.1 157157985 5589010 complement(4242843..4243082) 1 NC_009801.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 4243082 atpE 5589010 atpE Escherichia coli E24377A ATP synthase F0F1 subunit C YP_001465228.1 4242843 R 331111 CDS YP_001465229.1 157156239 5587259 complement(4243129..4243944) 1 NC_009801.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 4243944 atpB 5587259 atpB Escherichia coli E24377A ATP synthase F0F1 subunit A YP_001465229.1 4243129 R 331111 CDS YP_001465230.1 157159303 5586609 complement(4243953..4244333) 1 NC_009801.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 4244333 atpI 5586609 atpI Escherichia coli E24377A F0F1 ATP synthase subunit I YP_001465230.1 4243953 R 331111 CDS YP_001465231.1 157155354 5590214 complement(4245641..4247530) 1 NC_009801.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 4247530 gidA 5590214 gidA Escherichia coli E24377A tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_001465231.1 4245641 R 331111 CDS YP_001465232.1 157158881 5590124 complement(4247909..4248352) 1 NC_009801.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 4248352 mioC 5590124 mioC Escherichia coli E24377A flavodoxin YP_001465232.1 4247909 R 331111 CDS YP_001465233.1 157155705 5588587 complement(4248442..4248900) 1 NC_009801.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 4248900 asnC 5588587 asnC Escherichia coli E24377A DNA-binding transcriptional regulator AsnC YP_001465233.1 4248442 R 331111 CDS YP_001465234.1 157156517 5589505 4249052..4250044 1 NC_009801.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4250044 asnA 5589505 asnA Escherichia coli E24377A asparagine synthetase AsnA YP_001465234.1 4249052 D 331111 CDS YP_001465235.1 157158067 5587769 complement(4250049..4251500) 1 NC_009801.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein 4251500 yieM 5587769 yieM Escherichia coli E24377A hypothetical protein YP_001465235.1 4250049 R 331111 CDS YP_001465236.1 157157819 5589531 complement(4251494..4252990) 1 NC_009801.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA 4252990 5589531 EcE24377A_4262 Escherichia coli E24377A regulatory ATPase RavA YP_001465236.1 4251494 R 331111 CDS YP_001465237.1 157159419 5587761 4253213..4255081 1 NC_009801.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4255081 trkD 5587761 trkD Escherichia coli E24377A potassium transport protein Kup YP_001465237.1 4253213 D 331111 CDS YP_001465238.1 157159151 5589927 4255248..4255667 1 NC_009801.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4255667 rbsD 5589927 rbsD Escherichia coli E24377A D-ribose pyranase YP_001465238.1 4255248 D 331111 CDS YP_001465239.1 157158385 5587294 4255675..4257180 1 NC_009801.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 4257180 rbsA 5587294 rbsA Escherichia coli E24377A D-ribose transporter ATP-binding protein YP_001465239.1 4255675 D 331111 CDS YP_001465240.1 157155741 5589292 4257185..4258150 1 NC_009801.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4258150 rbsC 5589292 rbsC Escherichia coli E24377A ribose ABC transporter permease YP_001465240.1 4257185 D 331111 CDS YP_001465241.1 157155054 5589708 4258181..4259065 1 NC_009801.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4259065 rbsB 5589708 rbsB Escherichia coli E24377A D-ribose transporter subunit RbsB YP_001465241.1 4258181 D 331111 CDS YP_001465242.1 157157898 5590231 4259191..4260120 1 NC_009801.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4260120 rbsK 5590231 rbsK Escherichia coli E24377A ribokinase YP_001465242.1 4259191 D 331111 CDS YP_001465243.1 157156677 5587721 4260124..4261116 1 NC_009801.1 DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4261116 rbsR 5587721 rbsR Escherichia coli E24377A transcriptional repressor RbsR YP_001465243.1 4260124 D 331111 CDS YP_001465244.1 157157369 5587387 complement(4261082..4262485) 1 NC_009801.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; DHA2 family drug:H+ antiporter-1 4262485 5587387 EcE24377A_4269 Escherichia coli E24377A DHA2 family drug:H+ antiporter-1 YP_001465244.1 4261082 R 331111 CDS YP_001465245.1 157156315 5587859 complement(4262532..4263224) 1 NC_009801.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 4263224 5587859 EcE24377A_4271 Escherichia coli E24377A GntR family transcriptional regulator YP_001465245.1 4262532 R 331111 CDS YP_001465246.1 157157500 5586547 complement(4269025..4269864) 1 NC_009801.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 4269864 hdfR 5586547 hdfR Escherichia coli E24377A transcriptional regulator HdfR YP_001465246.1 4269025 R 331111 CDS YP_001465247.1 157159390 5586274 4269983..4270321 1 NC_009801.1 identified by similarity to GB:AAZ90461.1; match to protein family HMM PF04219; hypothetical protein 4270321 5586274 EcE24377A_4277 Escherichia coli E24377A hypothetical protein YP_001465247.1 4269983 D 331111 CDS YP_001465248.1 157156172 5588438 complement(4270347..4271867) 1 NC_009801.1 among the AAA+ ATPases, the YifB protease belongs to the Helix 2 insert clade; unknown function; ATP-dependent protease 4271867 5588438 EcE24377A_4278 Escherichia coli E24377A ATP-dependent protease YP_001465248.1 4270347 R 331111 CDS YP_001465249.1 157158014 5590788 4272458..4274104 1 NC_009801.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4274104 ilvG 5590788 ilvG Escherichia coli E24377A acetolactate synthase 2 catalytic subunit YP_001465249.1 4272458 D 331111 CDS YP_001465250.1 157154747 5586651 4274101..4274364 1 NC_009801.1 identified by similarity to SP:P0ADG3; acetolactate synthase 2 regulatory subunit 4274364 ilvM 5586651 ilvM Escherichia coli E24377A acetolactate synthase 2 regulatory subunit YP_001465250.1 4274101 D 331111 CDS YP_001465251.1 157158223 5587062 4274384..4275313 1 NC_009801.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4275313 ilvE 5587062 ilvE Escherichia coli E24377A branched-chain amino acid aminotransferase YP_001465251.1 4274384 D 331111 CDS YP_001465252.1 157155507 5589972 4275378..4277228 1 NC_009801.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4277228 ilvD 5589972 ilvD Escherichia coli E24377A dihydroxy-acid dehydratase YP_001465252.1 4275378 D 331111 CDS YP_001465253.1 157159450 5590154 4277231..4278775 1 NC_009801.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4278775 ilvA 5590154 ilvA Escherichia coli E24377A threonine dehydratase YP_001465253.1 4277231 D 331111 CDS YP_001465254.1 157158220 5586725 complement(4278772..4279662) 1 NC_009801.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 4279662 ilvY 5586725 ilvY Escherichia coli E24377A DNA-binding transcriptional regulator IlvY YP_001465254.1 4278772 R 331111 CDS YP_001465255.1 157156237 5590085 4279812..4281287 1 NC_009801.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4281287 ilvC 5590085 ilvC Escherichia coli E24377A ketol-acid reductoisomerase YP_001465255.1 4279812 D 331111 CDS YP_001465256.1 157159000 5586105 complement(4281374..4281655) 1 NC_009801.1 identified by match to protein family HMM PF00639; peptidyl-prolyl cis-trans isomerase C 4281655 ppiC 5586105 ppiC Escherichia coli E24377A peptidyl-prolyl cis-trans isomerase C YP_001465256.1 4281374 R 331111 CDS YP_001465257.1 157157554 5587249 complement(4281854..4282303) 1 NC_009801.1 identified by similarity to GB:BAC41601.1; hypothetical protein 4282303 5587249 EcE24377A_4287 Escherichia coli E24377A hypothetical protein YP_001465257.1 4281854 R 331111 CDS YP_001465258.1 157154755 5589259 4282520..4284541 1 NC_009801.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4284541 rep 5589259 rep Escherichia coli E24377A ATP-dependent DNA helicase Rep YP_001465258.1 4282520 D 331111 CDS YP_001465259.1 157155434 5587305 complement(4284588..4286072) 1 NC_009801.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase 4286072 gppA 5587305 gppA Escherichia coli E24377A guanosine pentaphosphate phosphohydrolase YP_001465259.1 4284588 R 331111 CDS YP_001465260.1 157156015 5587825 4286178..4286276 1 NC_009801.1 identified by glimmer; hypothetical protein 4286276 5587825 EcE24377A_4291 Escherichia coli E24377A hypothetical protein YP_001465260.1 4286178 D 331111 CDS YP_001465261.1 157156932 5586486 complement(4286206..4287471) 1 NC_009801.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 4287471 rhlB 5586486 rhlB Escherichia coli E24377A ATP-dependent RNA helicase RhlB YP_001465261.1 4286206 R 331111 CDS YP_001465262.1 157158635 5590840 4287602..4287931 1 NC_009801.1 identified by similarity to SP:P0AA25; match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 4287931 trxA 5590840 trxA Escherichia coli E24377A thioredoxin YP_001465262.1 4287602 D 331111 CDS YP_001465263.1 157155913 5587858 4288258..4289517 1 NC_009801.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4289517 rho 5587858 rho Escherichia coli E24377A transcription termination factor Rho YP_001465263.1 4288258 D 331111 CDS YP_001465264.1 157159061 5588238 4289527..4289745 1 NC_009801.1 identified by glimmer; hypothetical protein 4289745 5588238 EcE24377A_4294 Escherichia coli E24377A hypothetical protein YP_001465264.1 4289527 D 331111 CDS YP_001465265.1 157158592 5590619 4289757..4290860 1 NC_009801.1 identified by match to protein family HMM PF00953; match to protein family HMM TIGR02380; undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase 4290860 wecA 5590619 wecA Escherichia coli E24377A undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase YP_001465265.1 4289757 D 331111 CDS YP_001465266.1 157155763 5586465 4290872..4291918 1 NC_009801.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4291918 5586465 EcE24377A_4296 Escherichia coli E24377A lipopolysaccharide biosynthesis protein WzzE YP_001465266.1 4290872 D 331111 CDS YP_001465267.1 157156617 5587937 4291974..4293104 1 NC_009801.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236; UDP-N-acetylglucosamine 2-epimerase 4293104 5587937 EcE24377A_4297 Escherichia coli E24377A UDP-N-acetylglucosamine 2-epimerase YP_001465267.1 4291974 D 331111 CDS YP_001465268.1 157158288 5587224 4293101..4294363 1 NC_009801.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4294363 wecC 5587224 wecC Escherichia coli E24377A UDP-N-acetyl-D-mannosamine dehydrogenase YP_001465268.1 4293101 D 331111 CDS YP_001465269.1 157155600 5590411 4294363..4295430 1 NC_009801.1 identified by similarity to SP:P27830; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; dTDP-glucose 4,6-dehydratase 4295430 rfbB1 5590411 rfbB1 Escherichia coli E24377A dTDP-glucose 4,6-dehydratase YP_001465269.1 4294363 D 331111 CDS YP_001465270.1 157157955 5587539 4295449..4296330 1 NC_009801.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidylyltransferase 4296330 rfbA2 5587539 rfbA2 Escherichia coli E24377A glucose-1-phosphate thymidylyltransferase YP_001465270.1 4295449 D 331111 CDS YP_001465271.1 157159420 5589330 4296437..4296982 1 NC_009801.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR02382; TDP-fucosamine acetyltransferase 4296982 wecD 5589330 wecD Escherichia coli E24377A TDP-fucosamine acetyltransferase YP_001465271.1 4296437 D 331111 CDS YP_001465272.1 157158755 5589928 4296987..4298117 1 NC_009801.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4298117 wecE 5589928 wecE Escherichia coli E24377A TDP-4-oxo-6-deoxy-D-glucose transaminase YP_001465272.1 4296987 D 331111 CDS YP_001465273.1 157158132 5586713 4298119..4299369 1 NC_009801.1 polysaccharide biosynthesis protein 4299369 5586713 EcE24377A_4304 Escherichia coli E24377A polysaccharide biosynthesis protein YP_001465273.1 4298119 D 331111 CDS YP_001465274.1 157158118 5587432 complement(4299318..4299410) 1 NC_009801.1 identified by glimmer; hypothetical protein 4299410 5587432 EcE24377A_4303 Escherichia coli E24377A hypothetical protein YP_001465274.1 4299318 R 331111 CDS YP_001465275.1 157157567 5590275 4299366..4300445 1 NC_009801.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4300445 wecF 5590275 wecF Escherichia coli E24377A 4-alpha-L-fucosyltransferase YP_001465275.1 4299366 D 331111 CDS YP_001465276.1 157157055 5588568 4300442..4301794 1 NC_009801.1 enterobacterial common antigen polymerase; common antigen polymerase 4301794 wzyE 5588568 wzyE Escherichia coli E24377A common antigen polymerase YP_001465276.1 4300442 D 331111 CDS YP_001465277.1 157156033 5587375 4301797..4302537 1 NC_009801.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696; UDP-N-acetyl-D-mannosaminuronic acid transferase 4302537 5587375 EcE24377A_4307 Escherichia coli E24377A UDP-N-acetyl-D-mannosaminuronic acid transferase YP_001465277.1 4301797 D 331111 CDS YP_001465278.1 157154802 5585962 complement(4302608..4302706) 1 NC_009801.1 identified by glimmer; hypothetical protein 4302706 5585962 EcE24377A_4308 Escherichia coli E24377A hypothetical protein YP_001465278.1 4302608 R 331111 CDS YP_001465279.1 157159029 5587804 4302728..4304113 1 NC_009801.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transporter 4304113 5587804 EcE24377A_4309 Escherichia coli E24377A transporter YP_001465279.1 4302728 D 331111 CDS YP_001465280.1 157158579 5588766 4304799..4306034 1 NC_009801.1 ydeM; identified by similarity to SP:P25550; match to protein family HMM PF04055; arylsulfatase 4306034 aslB 5588766 aslB Escherichia coli E24377A arylsulfatase YP_001465280.1 4304799 D 331111 CDS YP_001465281.1 157159354 5588320 complement(4306118..4306279) 1 NC_009801.1 arylsulfatase 4306279 5588320 EcE24377A_4315 Escherichia coli E24377A arylsulfatase YP_001465281.1 4306118 R 331111 CDS YP_001465282.1 157158160 5590680 complement(4306422..4306559) 1 NC_009801.1 identified by glimmer; hypothetical protein 4306559 5590680 EcE24377A_4316 Escherichia coli E24377A hypothetical protein YP_001465282.1 4306422 R 331111 CDS YP_001465283.1 157157643 5585971 complement(4306958..4308154) 1 NC_009801.1 identified by match to protein family HMM PF07219; match to protein family HMM PF07719; match to protein family HMM TIGR00540; protoheme IX biogenesis protein 4308154 hemY 5585971 hemY Escherichia coli E24377A protoheme IX biogenesis protein YP_001465283.1 4306958 R 331111 CDS YP_001465284.1 157157263 5588114 complement(4308157..4309350) 1 NC_009801.1 identified by match to protein family HMM PF04375; uroporphyrinogen III C-methyltransferase 4309350 5588114 EcE24377A_4318 Escherichia coli E24377A uroporphyrinogen III C-methyltransferase YP_001465284.1 4308157 R 331111 CDS YP_001465285.1 157156739 5589588 complement(4309372..4310112) 1 NC_009801.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 4310112 hemD 5589588 hemD Escherichia coli E24377A uroporphyrinogen-III synthase YP_001465285.1 4309372 R 331111 CDS YP_001465286.1 157156845 5587255 complement(4310109..4311071) 1 NC_009801.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 4311071 hemC 5587255 hemC Escherichia coli E24377A porphobilinogen deaminase YP_001465286.1 4310109 R 331111 CDS YP_001465287.1 157156146 5590660 4311437..4313983 1 NC_009801.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4313983 cyaA 5590660 cyaA Escherichia coli E24377A adenylate cyclase YP_001465287.1 4311437 D 331111 CDS YP_001465288.1 157155891 5590095 complement(4314023..4314343) 1 NC_009801.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 4314343 cyaY 5590095 cyaY Escherichia coli E24377A frataxin-like protein YP_001465288.1 4314023 R 331111 CDS YP_001465289.1 157155110 5587446 complement(4314391..4315704) 1 NC_009801.1 hypothetical protein 4315704 5587446 EcE24377A_4323 Escherichia coli E24377A hypothetical protein YP_001465289.1 4314391 R 331111 CDS YP_001465290.1 157159280 5589147 complement(4315701..4317179) 1 NC_009801.1 lipoprotein 4317179 5589147 EcE24377A_4324 Escherichia coli E24377A lipoprotein YP_001465290.1 4315701 R 331111 CDS YP_001465291.1 157156742 5590601 complement(4318108..4318242) 1 NC_009801.1 identified by glimmer; hypothetical protein 4318242 5590601 EcE24377A_4326 Escherichia coli E24377A hypothetical protein YP_001465291.1 4318108 R 331111 CDS YP_001465292.1 157154951 5587331 4318451..4318654 1 NC_009801.1 lipoprotein 4318654 5587331 EcE24377A_4327 Escherichia coli E24377A lipoprotein YP_001465292.1 4318451 D 331111 CDS YP_001465293.1 157158618 5589486 4318691..4319515 1 NC_009801.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4319515 dapF 5589486 dapF Escherichia coli E24377A diaminopimelate epimerase YP_001465293.1 4318691 D 331111 CDS YP_001465294.1 157158556 5590328 4319512..4320219 1 NC_009801.1 identified by match to protein family HMM PF04340; hypothetical protein 4320219 5590328 EcE24377A_4329 Escherichia coli E24377A hypothetical protein YP_001465294.1 4319512 D 331111 CDS YP_001465295.1 157159369 5589813 4320216..4321112 1 NC_009801.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4321112 xerC 5589813 xerC Escherichia coli E24377A site-specific tyrosine recombinase XerC YP_001465295.1 4320216 D 331111 CDS YP_001465296.1 157157210 5589618 4321112..4321828 1 NC_009801.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4321828 5589618 EcE24377A_4331 Escherichia coli E24377A flavin mononucleotide phosphatase YP_001465296.1 4321112 D 331111 CDS YP_001465297.1 157158058 5586191 4321912..4324074 1 NC_009801.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4324074 uvrD 5586191 uvrD Escherichia coli E24377A DNA-dependent helicase II YP_001465297.1 4321912 D 331111 CDS YP_001465298.1 157158314 5587000 complement(4324221..4324985) 1 NC_009801.1 hypothetical protein 4324985 5587000 EcE24377A_4333 Escherichia coli E24377A hypothetical protein YP_001465298.1 4324221 R 331111 CDS YP_001465299.1 157158684 5588514 4324977..4325111 1 NC_009801.1 identified by glimmer; hypothetical protein 4325111 5588514 EcE24377A_4334 Escherichia coli E24377A hypothetical protein YP_001465299.1 4324977 D 331111 CDS YP_001465300.1 157159364 5586723 4325355..4326305 1 NC_009801.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4326305 corA 5586723 corA Escherichia coli E24377A magnesium/nickel/cobalt transporter CorA YP_001465300.1 4325355 D 331111 CDS YP_001465301.1 157155571 5590077 4326311..4326412 1 NC_009801.1 identified by glimmer; hypothetical protein 4326412 5590077 EcE24377A_4337 Escherichia coli E24377A hypothetical protein YP_001465301.1 4326311 D 331111 CDS YP_001465302.1 157154904 5589381 complement(4326359..4326838) 1 NC_009801.1 identified by match to protein family HMM PF06092; hypothetical protein 4326838 5589381 EcE24377A_4336 Escherichia coli E24377A hypothetical protein YP_001465302.1 4326359 R 331111 CDS YP_001465303.1 157157285 5590332 complement(4326835..4327683) 1 NC_009801.1 identified by match to protein family HMM TIGR03034; hypothetical protein 4327683 5590332 EcE24377A_4338 Escherichia coli E24377A hypothetical protein YP_001465303.1 4326835 R 331111 CDS YP_001465304.1 157157940 5587503 4327813..4328016 1 NC_009801.1 identified by glimmer; hypothetical protein 4328016 5587503 EcE24377A_4339 Escherichia coli E24377A hypothetical protein YP_001465304.1 4327813 D 331111 CDS YP_001465305.1 157158296 5587972 complement(4328986..4329873) 1 NC_009801.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688; RarD protein 4329873 rarD 5587972 rarD Escherichia coli E24377A RarD protein YP_001465305.1 4328986 R 331111 CDS YP_001465306.1 157158817 5589693 complement(4329925..4330410) 1 NC_009801.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 4330410 5589693 EcE24377A_4341 Escherichia coli E24377A hypothetical protein YP_001465306.1 4329925 R 331111 CDS YP_001465307.1 157159347 5588306 4330557..4331426 1 NC_009801.1 catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4331426 pldA 5588306 pldA Escherichia coli E24377A phospholipase A YP_001465307.1 4330557 D 331111 CDS YP_001465308.1 157157237 5587866 4331559..4333388 1 NC_009801.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4333388 recQ 5587866 recQ Escherichia coli E24377A ATP-dependent DNA helicase RecQ YP_001465308.1 4331559 D 331111 CDS YP_001465309.1 157157002 5586324 4333458..4334072 1 NC_009801.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949; threonine efflux system 4334072 rhtC 5586324 rhtC Escherichia coli E24377A threonine efflux system YP_001465309.1 4333458 D 331111 CDS YP_001465310.1 157155928 5590291 complement(4334134..4334754) 1 NC_009801.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949; homoserine/homoserine lactone efflux protein 4334754 rhtB 5590291 rhtB Escherichia coli E24377A homoserine/homoserine lactone efflux protein YP_001465310.1 4334134 R 331111 CDS YP_001465311.1 157155555 5589489 4334865..4335887 1 NC_009801.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4335887 pldB 5589489 pldB Escherichia coli E24377A lysophospholipase L2 YP_001465311.1 4334865 D 331111 CDS YP_001465312.1 157155533 5586182 4335895..4336695 1 NC_009801.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4336695 5586182 EcE24377A_4347 Escherichia coli E24377A sugar phosphatase YP_001465312.1 4335895 D 331111 CDS YP_001465313.1 157158733 5589318 4336771..4337670 1 NC_009801.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950; drug/metabolite exporter (DME) family protein 4337670 5589318 EcE24377A_4349 Escherichia coli E24377A drug/metabolite exporter (DME) family protein YP_001465313.1 4336771 D 331111 CDS YP_001465314.1 157154863 5590391 complement(4337558..4338511) 1 NC_009801.1 identified by similarity to SP:P0A9F9; match to protein family HMM PF00126; match to protein family HMM PF03466; transcriptional regulator MetR 4338511 metR 5590391 metR Escherichia coli E24377A transcriptional regulator MetR YP_001465314.1 4337558 R 331111 CDS YP_001465315.1 157158034 5589931 4338628..4340889 1 NC_009801.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 4340889 metE 5589931 metE Escherichia coli E24377A 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_001465315.1 4338628 D 331111 CDS YP_001465316.1 157157944 5587571 complement(4340928..4341743) 1 NC_009801.1 identified by match to protein family HMM PF01738; dienelactone hydrolase 4341743 5587571 EcE24377A_4351 Escherichia coli E24377A dienelactone hydrolase YP_001465316.1 4340928 R 331111 CDS YP_001465317.1 157155953 5590005 4342005..4342766 1 NC_009801.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4342766 udp 5590005 udp Escherichia coli E24377A uridine phosphorylase YP_001465317.1 4342005 D 331111 CDS YP_001465318.1 157154849 5589322 4342907..4344334 1 NC_009801.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4344334 rmuC 5589322 rmuC Escherichia coli E24377A DNA recombination protein RmuC YP_001465318.1 4342907 D 331111 CDS YP_001465319.1 157156758 5589519 4344429..4345184 1 NC_009801.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4345184 ubiE 5589519 ubiE Escherichia coli E24377A ubiquinone/menaquinone biosynthesis methyltransferase YP_001465319.1 4344429 D 331111 CDS YP_001465320.1 157156110 5590166 4345198..4345803 1 NC_009801.1 identified by match to protein family HMM PF06843; hypothetical protein 4345803 5590166 EcE24377A_4355 Escherichia coli E24377A hypothetical protein YP_001465320.1 4345198 D 331111 CDS YP_001465321.1 157158098 5590769 4345800..4347440 1 NC_009801.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4347440 ubiB 5590769 ubiB Escherichia coli E24377A ubiquinone biosynthesis protein UbiB YP_001465321.1 4345800 D 331111 CDS YP_001465322.1 157157423 5586210 4347519..4347788 1 NC_009801.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase A 4347788 tatA 5586210 tatA Escherichia coli E24377A twin arginine translocase A YP_001465322.1 4347519 D 331111 CDS YP_001465323.1 157159437 5588484 4347792..4348307 1 NC_009801.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4348307 tatB 5588484 tatB Escherichia coli E24377A sec-independent translocase YP_001465323.1 4347792 D 331111 CDS YP_001465324.1 157158778 5587619 4348310..4349086 1 NC_009801.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4349086 tatC 5587619 tatC Escherichia coli E24377A twin-arginine protein translocation system subunit TatC YP_001465324.1 4348310 D 331111 CDS YP_001465325.1 157158037 5587005 4349128..4349910 1 NC_009801.1 magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4349910 tatD 5587005 tatD Escherichia coli E24377A DNase TatD YP_001465325.1 4349128 D 331111 CDS YP_001465326.1 157157494 5586647 complement(4349907..4350395) 1 NC_009801.1 identified by similarity to SP:P26614; match to protein family HMM PF02357; match to protein family HMM TIGR01955; transcriptional activator RfaH 4350395 rfaH 5586647 rfaH Escherichia coli E24377A transcriptional activator RfaH YP_001465326.1 4349907 R 331111 CDS YP_001465327.1 157155071 5586698 4350562..4352055 1 NC_009801.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4352055 ubiD 5586698 ubiD Escherichia coli E24377A 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001465327.1 4350562 D 331111 CDS YP_001465328.1 157157049 5587770 4352101..4352802 1 NC_009801.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4352802 fre 5587770 fre Escherichia coli E24377A FMN reductase YP_001465328.1 4352101 D 331111 CDS YP_001465329.1 157158775 5587876 complement(4352994..4354157) 1 NC_009801.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 4354157 fadA 5587876 fadA Escherichia coli E24377A 3-ketoacyl-CoA thiolase YP_001465329.1 4352994 R 331111 CDS YP_001465330.1 157158390 5586338 complement(4354167..4356356) 1 NC_009801.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 4356356 fadB 5586338 fadB Escherichia coli E24377A multifunctional fatty acid oxidation complex subunit alpha YP_001465330.1 4354167 R 331111 CDS YP_001465331.1 157157716 5589989 4356546..4357877 1 NC_009801.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4357877 pepQ 5589989 pepQ Escherichia coli E24377A proline dipeptidase YP_001465331.1 4356546 D 331111 CDS YP_001465332.1 157157329 5588005 4357874..4358491 1 NC_009801.1 identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257; hypothetical protein 4358491 5588005 EcE24377A_4367 Escherichia coli E24377A hypothetical protein YP_001465332.1 4357874 D 331111 CDS YP_001465333.1 157156679 5589751 4358530..4359981 1 NC_009801.1 identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933; potassium transporter 4359981 trkH 5589751 trkH Escherichia coli E24377A potassium transporter YP_001465333.1 4358530 D 331111 CDS YP_001465334.1 157156299 5590419 4359993..4360538 1 NC_009801.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4360538 hemG 5590419 hemG Escherichia coli E24377A protoporphyrinogen oxidase YP_001465334.1 4359993 D 331111 CDS YP_001465335.1 157158267 5587993 complement(4366119..4366646) 1 NC_009801.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B 4366646 mobB 5587993 mobB Escherichia coli E24377A molybdopterin-guanine dinucleotide biosynthesis protein B YP_001465335.1 4366119 R 331111 CDS YP_001465336.1 157159213 5586816 complement(4366628..4367212) 1 NC_009801.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 4367212 mobA 5586816 mobA Escherichia coli E24377A molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_001465336.1 4366628 R 331111 CDS YP_001465337.1 157158659 5587463 complement(4367261..4367362) 1 NC_009801.1 identified by glimmer; hypothetical protein 4367362 5587463 EcE24377A_4375 Escherichia coli E24377A hypothetical protein YP_001465337.1 4367261 R 331111 CDS YP_001465338.1 157158488 5587734 4367282..4367551 1 NC_009801.1 identified by match to protein family HMM PF06288; hypothetical protein 4367551 5587734 EcE24377A_4376 Escherichia coli E24377A hypothetical protein YP_001465338.1 4367282 D 331111 CDS YP_001465339.1 157155589 5590295 4367628..4368614 1 NC_009801.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4368614 5590295 EcE24377A_4377 Escherichia coli E24377A serine/threonine protein kinase YP_001465339.1 4367628 D 331111 CDS YP_001465340.1 157155214 5590815 4368631..4369257 1 NC_009801.1 identified by similarity to SP:P52235; match to protein family HMM PF01323; protein disulfide isomerase I 4369257 dsbA 5590815 dsbA Escherichia coli E24377A protein disulfide isomerase I YP_001465340.1 4368631 D 331111 CDS YP_001465341.1 157156538 5586857 4369412..4370842 1 NC_009801.1 yihF; identified by match to protein family HMM PF06097; hypothetical protein 4370842 5586857 EcE24377A_4379 Escherichia coli E24377A hypothetical protein YP_001465341.1 4369412 D 331111 CDS YP_001465342.1 157156273 5586611 complement(4370883..4371788) 1 NC_009801.1 identified by match to protein family HMM PF01553; acyltransferase 4371788 5586611 EcE24377A_4380 Escherichia coli E24377A acyltransferase YP_001465342.1 4370883 R 331111 CDS YP_001465343.1 157158240 5588790 complement(4371935..4372177) 1 NC_009801.1 identified by glimmer; hypothetical protein 4372177 5588790 EcE24377A_4381 Escherichia coli E24377A hypothetical protein YP_001465343.1 4371935 R 331111 CDS YP_001465344.1 157158243 5587789 4372179..4374965 1 NC_009801.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4374965 polA 5587789 polA Escherichia coli E24377A DNA polymerase I YP_001465344.1 4372179 D 331111 CDS YP_001465345.1 157156230 5587230 complement(4375347..4375979) 1 NC_009801.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 4375979 engB 5587230 engB Escherichia coli E24377A ribosome biogenesis GTP-binding protein YsxC YP_001465345.1 4375347 R 331111 CDS YP_001465346.1 157157778 5586884 4376561..4377070 1 NC_009801.1 identified by similarity to SP:Q8FBG9; match to protein family HMM PF04220; hypothetical protein 4377070 5586884 EcE24377A_4384 Escherichia coli E24377A hypothetical protein YP_001465346.1 4376561 D 331111 CDS YP_001465347.1 157157152 5586964 complement(4377144..4377260) 1 NC_009801.1 identified by glimmer; hypothetical protein 4377260 5586964 EcE24377A_4385 Escherichia coli E24377A hypothetical protein YP_001465347.1 4377144 R 331111 CDS YP_001465348.1 157159135 5588897 4377259..4378632 1 NC_009801.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4378632 hemN 5588897 hemN Escherichia coli E24377A coproporphyrinogen III oxidase YP_001465348.1 4377259 D 331111 CDS YP_001465349.1 157158502 5588259 complement(4378678..4378782) 1 NC_009801.1 identified by glimmer; hypothetical protein 4378782 5588259 EcE24377A_4387 Escherichia coli E24377A hypothetical protein YP_001465349.1 4378678 R 331111 CDS YP_001465350.1 157155508 5587791 complement(4378822..4378932) 1 NC_009801.1 identified by glimmer; hypothetical protein 4378932 5587791 EcE24377A_4389 Escherichia coli E24377A hypothetical protein YP_001465350.1 4378822 R 331111 CDS YP_001465351.1 157155281 5590155 complement(4379044..4380453) 1 NC_009801.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) 4380453 glnG 5590155 glnG Escherichia coli E24377A nitrogen regulation protein NR(I) YP_001465351.1 4379044 R 331111 CDS YP_001465352.1 157156886 5588647 complement(4380465..4381514) 1 NC_009801.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 4381514 glnL 5588647 glnL Escherichia coli E24377A nitrogen regulation protein NR(II) YP_001465352.1 4380465 R 331111 CDS YP_001465353.1 157155897 5587551 complement(4381688..4383097) 1 NC_009801.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 4383097 glnA 5587551 glnA Escherichia coli E24377A glutamine synthetase YP_001465353.1 4381688 R 331111 CDS YP_001465354.1 157155081 5587321 complement(4383087..4383197) 1 NC_009801.1 identified by glimmer; hypothetical protein 4383197 5587321 EcE24377A_4393 Escherichia coli E24377A hypothetical protein YP_001465354.1 4383087 R 331111 CDS YP_001465355.1 157157174 5590541 4383470..4385293 1 NC_009801.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394; GTP-binding protein 4385293 typA 5590541 typA Escherichia coli E24377A GTP-binding protein YP_001465355.1 4383470 D 331111 CDS YP_001465356.1 157157818 5588141 4385510..4386220 1 NC_009801.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 4386220 5588141 EcE24377A_4395 Escherichia coli E24377A GntR family transcriptional regulator YP_001465356.1 4385510 D 331111 CDS YP_001465357.1 157156441 5587760 4386228..4387208 1 NC_009801.1 identified by match to protein family HMM PF01261; AP endonuclease 4387208 5587760 EcE24377A_4396 Escherichia coli E24377A AP endonuclease YP_001465357.1 4386228 D 331111 CDS YP_001465358.1 157157068 5586720 4387310..4388575 1 NC_009801.1 identified by match to protein family HMM PF07690; major facilitator transporter 4388575 5586720 EcE24377A_4397 Escherichia coli E24377A major facilitator transporter YP_001465358.1 4387310 D 331111 CDS YP_001465359.1 157157075 5588129 complement(4388666..4389358) 1 NC_009801.1 porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown; outer membrane porin L 4389358 ompL 5588129 ompL Escherichia coli E24377A outer membrane porin L YP_001465359.1 4388666 R 331111 CDS YP_001465360.1 157155047 5588729 complement(4389426..4390829) 1 NC_009801.1 identified by match to protein family HMM TIGR00792; sugar (glycoside-Pentoside-hexuronide) transporter family protein 4390829 5588729 EcE24377A_4399 Escherichia coli E24377A sugar (glycoside-Pentoside-hexuronide) transporter family protein YP_001465360.1 4389426 R 331111 CDS YP_001465361.1 157155703 5585904 complement(4390872..4392278) 1 NC_009801.1 identified by match to protein family HMM TIGR00792; sugar transporter family protein 4392278 5585904 EcE24377A_4400 Escherichia coli E24377A sugar transporter family protein YP_001465361.1 4390872 R 331111 CDS YP_001465362.1 157159043 5590243 complement(4392303..4394339) 1 NC_009801.1 identified by match to protein family HMM PF01055; alpha-glucosidase 4394339 5590243 EcE24377A_4401 Escherichia coli E24377A alpha-glucosidase YP_001465362.1 4392303 R 331111 CDS YP_001465363.1 157155053 5587930 complement(4394538..4395440) 1 NC_009801.1 identified by match to protein family HMM PF01263; aldose-1-epimerase 4395440 5587930 EcE24377A_4402 Escherichia coli E24377A aldose-1-epimerase YP_001465363.1 4394538 R 331111 CDS YP_001465364.1 157155737 5590230 complement(4395578..4396819) 1 NC_009801.1 identified by match to protein family HMM PF07221; N-acylglucosamine 2-epimerase 4396819 5590230 EcE24377A_4403 Escherichia coli E24377A N-acylglucosamine 2-epimerase YP_001465364.1 4395578 R 331111 CDS YP_001465365.1 157158013 5589704 complement(4396836..4397714) 1 NC_009801.1 identified by match to protein family HMM PF01791; deoxyribose-phosphate aldolase 4397714 5589704 EcE24377A_4404 Escherichia coli E24377A deoxyribose-phosphate aldolase YP_001465365.1 4396836 R 331111 CDS YP_001465366.1 157157646 5586650 complement(4397738..4398634) 1 NC_009801.1 identified by match to protein family HMM PF03446; 3-hydroxyisobutyrate dehydrogenase 4398634 5586650 EcE24377A_4405 Escherichia coli E24377A 3-hydroxyisobutyrate dehydrogenase YP_001465366.1 4397738 R 331111 CDS YP_001465367.1 157159362 5586745 4398802..4399698 1 NC_009801.1 identified by match to protein family HMM PF00294; PfkB family kinase 4399698 5586745 EcE24377A_4406 Escherichia coli E24377A PfkB family kinase YP_001465367.1 4398802 D 331111 CDS YP_001465368.1 157158966 5587985 4399732..4400517 1 NC_009801.1 identified by match to protein family HMM PF00455; match to protein family HMM PF01022; match to protein family HMM PF08220; match to protein family HMM PF08279; DeoR family transcriptional regulator 4400517 5587985 EcE24377A_4407 Escherichia coli E24377A DeoR family transcriptional regulator YP_001465368.1 4399732 D 331111 CDS YP_001465369.1 157155452 5589943 4400616..4401215 1 NC_009801.1 identified by similarity to SP:P0A8Y4; match to protein family HMM PF00702; match to protein family HMM TIGR01509; phosphatase 4401215 yihX 5589943 yihX Escherichia coli E24377A phosphatase YP_001465369.1 4400616 D 331111 CDS YP_001465370.1 157154769 5586676 4401209..4402081 1 NC_009801.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4402081 rbn 5586676 rbn Escherichia coli E24377A ribonuclease BN YP_001465370.1 4401209 D 331111 CDS YP_001465371.1 157156807 5588466 4402078..4402515 1 NC_009801.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4402515 dtd 5588466 dtd Escherichia coli E24377A D-tyrosyl-tRNA(Tyr) deacylase YP_001465371.1 4402078 D 331111 CDS YP_001465372.1 157156308 5587563 4402560..4403501 1 NC_009801.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR02447; thioesterase/acetyltransferase domain-containing protein 4403501 5587563 EcE24377A_4411 Escherichia coli E24377A thioesterase/acetyltransferase domain-containing protein YP_001465372.1 4402560 D 331111 CDS YP_001465373.1 157155311 5587718 complement(4403565..4404473) 1 NC_009801.1 identified by match to protein family HMM PF07859; alpha/beta hydrolase 4404473 5587718 EcE24377A_4412 Escherichia coli E24377A alpha/beta hydrolase YP_001465373.1 4403565 R 331111 CDS YP_001465374.1 157154850 5590445 4404487..4404585 1 NC_009801.1 identified by glimmer; hypothetical protein 4404585 5590445 EcE24377A_4413 Escherichia coli E24377A hypothetical protein YP_001465374.1 4404487 D 331111 CDS YP_001465375.1 157156516 5589297 4404702..4405013 1 NC_009801.1 identified by similarity to GB:AAN83266.1; hypothetical protein 4405013 5589297 EcE24377A_4414 Escherichia coli E24377A hypothetical protein YP_001465375.1 4404702 D 331111 CDS YP_001465376.1 157157041 5587768 4405014..4405304 1 NC_009801.1 identified by match to protein family HMM PF01381; helix-turn-helix DNA-binding domain-containing protein 4405304 5587768 EcE24377A_4415 Escherichia coli E24377A helix-turn-helix DNA-binding domain-containing protein YP_001465376.1 4405014 D 331111 CDS YP_001465377.1 157155022 5588304 4405390..4405482 1 NC_009801.1 identified by glimmer; hypothetical protein 4405482 5588304 EcE24377A_4416 Escherichia coli E24377A hypothetical protein YP_001465377.1 4405390 D 331111 CDS YP_001465378.1 157158669 5587122 4406346..4406588 1 NC_009801.1 hypothetical protein 4406588 5587122 EcE24377A_4418 Escherichia coli E24377A hypothetical protein YP_001465378.1 4406346 D 331111 CDS YP_001465379.1 157157248 5590831 complement(4406817..4407797) 1 NC_009801.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 4407797 5590831 EcE24377A_4419 Escherichia coli E24377A IS621, transposase YP_001465379.1 4406817 R 331111 CDS YP_001465380.1 157157747 5590649 complement(4408196..4409125) 1 NC_009801.1 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 4409125 fdhE 5590649 fdhE Escherichia coli E24377A formate dehydrogenase accessory protein FdhE YP_001465380.1 4408196 R 331111 CDS YP_001465381.1 157155038 5588174 complement(4409122..4409757) 1 NC_009801.1 cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 4409757 fdoI 5588174 fdoI Escherichia coli E24377A formate dehydrogenase-O subunit gamma YP_001465381.1 4409122 R 331111 CDS YP_001465382.1 157155894 5590333 complement(4409754..4410656) 1 NC_009801.1 identified by similarity to SP:P0AAJ5; match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582; formate dehydrogenase-O, iron-sulfur subunit 4410656 fdoH 5590333 fdoH Escherichia coli E24377A formate dehydrogenase-O, iron-sulfur subunit YP_001465382.1 4409754 R 331111 CDS YP_001465383.1 157156322 5585993 4413723..4413977 1 NC_009801.1 identified by glimmer; hypothetical protein 4413977 5585993 EcE24377A_4424 Escherichia coli E24377A hypothetical protein YP_001465383.1 4413723 D 331111 CDS YP_001465384.1 157156856 5589082 4413946..4414746 1 NC_009801.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4414746 fdhD 5589082 fdhD Escherichia coli E24377A formate dehydrogenase accessory protein YP_001465384.1 4413946 D 331111 CDS YP_001465385.1 157155223 5588566 4414899..4415939 1 NC_009801.1 lipoprotein 4415939 5588566 EcE24377A_4426 Escherichia coli E24377A lipoprotein YP_001465385.1 4414899 D 331111 CDS YP_001465386.1 157155910 5588925 complement(4415989..4417737) 1 NC_009801.1 repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; frv operon regulatory protein 4417737 5588925 EcE24377A_4427 Escherichia coli E24377A frv operon regulatory protein YP_001465386.1 4415989 R 331111 CDS YP_001465387.1 157157925 5586970 complement(4417737..4418807) 1 NC_009801.1 with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars; fructose-specific phosphotransferase system protein FrvX 4418807 5586970 EcE24377A_4428 Escherichia coli E24377A fructose-specific phosphotransferase system protein FrvX YP_001465387.1 4417737 R 331111 CDS YP_001465388.1 157158434 5586988 complement(4418797..4420248) 1 NC_009801.1 identified by match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR01427; PTS system transporter subunits IIBC 4420248 5586988 EcE24377A_4429 Escherichia coli E24377A PTS system transporter subunits IIBC YP_001465388.1 4418797 R 331111 CDS YP_001465389.1 157157981 5588973 complement(4420259..4420705) 1 NC_009801.1 with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; fructose-like phosphotransferase system subunit EIIA 4420705 5588973 EcE24377A_4430 Escherichia coli E24377A fructose-like phosphotransferase system subunit EIIA YP_001465389.1 4420259 R 331111 CDS YP_001465390.1 157158332 5586033 complement(4420895..4421005) 1 NC_009801.1 identified by glimmer; hypothetical protein 4421005 5586033 EcE24377A_4431 Escherichia coli E24377A hypothetical protein YP_001465390.1 4420895 R 331111 CDS YP_001465391.1 157156113 5589784 complement(4421006..4421320) 1 NC_009801.1 identified by match to protein family HMM PF05336; match to protein family HMM TIGR02625; L-rhamnose 1-epimerase 4421320 rhaU 5589784 rhaU Escherichia coli E24377A L-rhamnose 1-epimerase YP_001465391.1 4421006 R 331111 CDS YP_001465392.1 157156798 5590040 complement(4421330..4422154) 1 NC_009801.1 identified by similarity to SP:P32169; match to protein family HMM PF00596; match to protein family HMM TIGR02624; rhamnulose-1-phosphate aldolase 4422154 rhaD 5590040 rhaD Escherichia coli E24377A rhamnulose-1-phosphate aldolase YP_001465392.1 4421330 R 331111 CDS YP_001465393.1 157154741 5587921 complement(4422396..4423655) 1 NC_009801.1 catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 4423655 rhaA 5587921 rhaA Escherichia coli E24377A L-rhamnose isomerase YP_001465393.1 4422396 R 331111 CDS YP_001465394.1 157155428 5589027 complement(4423652..4425121) 1 NC_009801.1 catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase 4425121 rhaB 5589027 rhaB Escherichia coli E24377A rhamnulokinase YP_001465394.1 4423652 R 331111 CDS YP_001465395.1 157158178 5588285 4425200..4425349 1 NC_009801.1 identified by glimmer; hypothetical protein 4425349 5588285 EcE24377A_4436 Escherichia coli E24377A hypothetical protein YP_001465395.1 4425200 D 331111 CDS YP_001465396.1 157158845 5588150 4425409..4426245 1 NC_009801.1 activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4426245 rhaS 5588150 rhaS Escherichia coli E24377A transcriptional activator RhaS YP_001465396.1 4425409 D 331111 CDS YP_001465397.1 157156879 5589229 4426229..4427167 1 NC_009801.1 activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4427167 rhaR 5589229 rhaR Escherichia coli E24377A transcriptional activator RhaR YP_001465397.1 4426229 D 331111 CDS YP_001465398.1 157157534 5586208 complement(4427164..4428198) 1 NC_009801.1 transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter 4428198 rhaT 5586208 rhaT Escherichia coli E24377A rhamnose-proton symporter YP_001465398.1 4427164 R 331111 CDS YP_001465399.1 157157036 5588968 4428483..4429103 1 NC_009801.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4429103 sodA 5588968 sodA Escherichia coli E24377A superoxide dismutase YP_001465399.1 4428483 D 331111 CDS YP_001465400.1 157157562 5587642 complement(4429144..4429260) 1 NC_009801.1 hypothetical protein 4429260 5587642 EcE24377A_4441 Escherichia coli E24377A hypothetical protein YP_001465400.1 4429144 R 331111 CDS YP_001465401.1 157155562 5586493 4429278..4429385 1 NC_009801.1 identified by glimmer; hypothetical protein 4429385 5586493 EcE24377A_4442 Escherichia coli E24377A hypothetical protein YP_001465401.1 4429278 D 331111 CDS YP_001465402.1 157155235 5589901 4429363..4430346 1 NC_009801.1 transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4430346 kdgT 5589901 kdgT Escherichia coli E24377A 2-keto-3-deoxygluconate permease YP_001465402.1 4429363 D 331111 CDS YP_001465403.1 157156061 5589811 4430495..4431169 1 NC_009801.1 identified by match to protein family HMM PF03473; match to protein family HMM PF03475; hypothetical protein 4431169 5589811 EcE24377A_4444 Escherichia coli E24377A hypothetical protein YP_001465403.1 4430495 D 331111 CDS YP_001465404.1 157156338 5586803 complement(4431275..4432648) 1 NC_009801.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 4432648 cpxA 5586803 cpxA Escherichia coli E24377A two-component sensor protein YP_001465404.1 4431275 R 331111 CDS YP_001465405.1 157158151 5587169 complement(4432645..4433343) 1 NC_009801.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR 4433343 cpxR 5587169 cpxR Escherichia coli E24377A DNA-binding transcriptional regulator CpxR YP_001465405.1 4432645 R 331111 CDS YP_001465406.1 157159185 5587510 4433493..4433993 1 NC_009801.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP 4433993 cpxP 5587510 cpxP Escherichia coli E24377A repressor CpxP YP_001465406.1 4433493 D 331111 CDS YP_001465407.1 157158687 5586159 4434142..4435044 1 NC_009801.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4435044 fieF 5586159 fieF Escherichia coli E24377A ferrous iron efflux protein F YP_001465407.1 4434142 D 331111 CDS YP_001465408.1 157155520 5590315 4435225..4436187 1 NC_009801.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4436187 pfkA 5590315 pfkA Escherichia coli E24377A 6-phosphofructokinase YP_001465408.1 4435225 D 331111 CDS YP_001465409.1 157154942 5590048 complement(4436213..4436356) 1 NC_009801.1 identified by glimmer; hypothetical protein 4436356 5590048 EcE24377A_4450 Escherichia coli E24377A hypothetical protein YP_001465409.1 4436213 R 331111 CDS YP_001465410.1 157157089 5586871 4436507..4437496 1 NC_009801.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971; sulfate transporter subunit 4437496 sbp 5586871 sbp Escherichia coli E24377A sulfate transporter subunit YP_001465410.1 4436507 D 331111 CDS YP_001465411.1 157155539 5590584 4437603..4438358 1 NC_009801.1 identified by match to protein family HMM PF02611; match to protein family HMM TIGR00672; CDP-diacylglycerol pyrophosphatase 4438358 cdh 5590584 cdh Escherichia coli E24377A CDP-diacylglycerol pyrophosphatase YP_001465411.1 4437603 D 331111 CDS YP_001465412.1 157159290 5587727 complement(4438413..4439180) 1 NC_009801.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 4439180 tpiA 5587727 tpiA Escherichia coli E24377A triosephosphate isomerase YP_001465412.1 4438413 R 331111 CDS YP_001465413.1 157157417 5588102 complement(4439288..4439887) 1 NC_009801.1 identified by match to protein family HMM PF07305; hypothetical protein 4439887 5588102 EcE24377A_4454 Escherichia coli E24377A hypothetical protein YP_001465413.1 4439288 R 331111 CDS YP_001465414.1 157156222 5590570 4439988..4440428 1 NC_009801.1 identified by match to protein family HMM PF05656; hypothetical protein 4440428 5590570 EcE24377A_4455 Escherichia coli E24377A hypothetical protein YP_001465414.1 4439988 D 331111 CDS YP_001465415.1 157156738 5587232 4440640..4440939 1 NC_009801.1 identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743; hypothetical protein 4440939 5587232 EcE24377A_4456 Escherichia coli E24377A hypothetical protein YP_001465415.1 4440640 D 331111 CDS YP_001465416.1 157156595 5587254 4440966..4441394 1 NC_009801.1 with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4441394 uspD 5587254 uspD Escherichia coli E24377A universal stress protein UspD YP_001465416.1 4440966 D 331111 CDS YP_001465417.1 157154725 5589500 complement(4441399..4442145) 1 NC_009801.1 identified by similarity to SP:P28861; match to protein family HMM PF00175; match to protein family HMM PF00970; ferredoxin-NADP reductase 4442145 fpr 5589500 fpr Escherichia coli E24377A ferredoxin-NADP reductase YP_001465417.1 4441399 R 331111 CDS YP_001465418.1 157155870 5586019 complement(4442242..4443252) 1 NC_009801.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 4443252 glpX 5586019 glpX Escherichia coli E24377A fructose 1,6-bisphosphatase II YP_001465418.1 4442242 R 331111 CDS YP_001465419.1 157158366 5588294 complement(4443388..4444896) 1 NC_009801.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 4444896 glpK 5588294 glpK Escherichia coli E24377A glycerol kinase YP_001465419.1 4443388 R 331111 CDS YP_001465420.1 157157499 5586042 complement(4444919..4445764) 1 NC_009801.1 identified by similarity to SP:P31140; match to protein family HMM PF00230; match to protein family HMM TIGR00861; glycerol uptake facilitator protein 4445764 glpF 5586042 glpF Escherichia coli E24377A glycerol uptake facilitator protein YP_001465420.1 4444919 R 331111 CDS YP_001465421.1 157158375 5588890 4446001..4446102 1 NC_009801.1 identified by glimmer; hypothetical protein 4446102 5588890 EcE24377A_4462 Escherichia coli E24377A hypothetical protein YP_001465421.1 4446001 D 331111 CDS YP_001465422.1 157156566 5590620 4446195..4446434 1 NC_009801.1 identified by match to protein family HMM PF06005; hypothetical protein 4446434 5590620 EcE24377A_4463 Escherichia coli E24377A hypothetical protein YP_001465422.1 4446195 D 331111 CDS YP_001465423.1 157156032 5588713 complement(4446519..4447004) 1 NC_009801.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 4447004 rraA 5588713 rraA Escherichia coli E24377A ribonuclease activity regulator protein RraA YP_001465423.1 4446519 R 331111 CDS YP_001465424.1 157154893 5585930 complement(4447097..4448023) 1 NC_009801.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 4448023 menA 5585930 menA Escherichia coli E24377A 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_001465424.1 4447097 R 331111 CDS YP_001465425.1 157155037 5587633 complement(4448090..4449421) 1 NC_009801.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 4449421 hslU 5587633 hslU Escherichia coli E24377A ATP-dependent protease ATP-binding subunit HslU YP_001465425.1 4448090 R 331111 CDS YP_001465426.1 157159294 5589988 complement(4449431..4449961) 1 NC_009801.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 4449961 hslV 5589988 hslV Escherichia coli E24377A ATP-dependent protease peptidase subunit YP_001465426.1 4449431 R 331111 CDS YP_001465427.1 157158424 5587596 complement(4450054..4451013) 1 NC_009801.1 identified by similarity to SP:P29131; match to protein family HMM PF05036; match to protein family HMM TIGR02223; essential cell division protein FtsN 4451013 ftsN 5587596 ftsN Escherichia coli E24377A essential cell division protein FtsN YP_001465427.1 4450054 R 331111 CDS YP_001465428.1 157158197 5589376 complement(4451105..4452130) 1 NC_009801.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 4452130 cytR 5589376 cytR Escherichia coli E24377A DNA-binding transcriptional regulator CytR YP_001465428.1 4451105 R 331111 CDS YP_001465429.1 157155621 5586752 complement(4452286..4454484) 1 NC_009801.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 4454484 priA 5586752 priA Escherichia coli E24377A primosome assembly protein PriA YP_001465429.1 4452286 R 331111 CDS YP_001465430.1 157158799 5586378 4454687..4454899 1 NC_009801.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 4454899 rpmE 5586378 rpmE Escherichia coli E24377A 50S ribosomal protein L31 YP_001465430.1 4454687 D 331111 CDS YP_001465431.1 157157771 5588654 4455059..4459156 1 NC_009801.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643; protein rhsA 4459156 5588654 EcE24377A_4473 Escherichia coli E24377A protein rhsA YP_001465431.1 4455059 D 331111 CDS YP_001465432.1 157157110 5590677 complement(4460283..4460384) 1 NC_009801.1 lipoprotein 4460384 5590677 EcE24377A_4474 Escherichia coli E24377A lipoprotein YP_001465432.1 4460283 R 331111 CDS YP_001465433.1 157157636 5587545 complement(4460388..4460996) 1 NC_009801.1 member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase 4460996 5587545 EcE24377A_4475 Escherichia coli E24377A peptidoglycan peptidase YP_001465433.1 4460388 R 331111 CDS YP_001465434.1 157156959 5590761 4461009..4461125 1 NC_009801.1 identified by glimmer; hypothetical protein 4461125 5590761 EcE24377A_4476 Escherichia coli E24377A hypothetical protein YP_001465434.1 4461009 D 331111 CDS YP_001465435.1 157154861 5587383 complement(4461223..4462206) 1 NC_009801.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 4462206 5587383 EcE24377A_4477 Escherichia coli E24377A IS621, transposase YP_001465435.1 4461223 R 331111 CDS YP_001465436.1 157155613 5590023 complement(4462454..4462771) 1 NC_009801.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 4462771 metJ 5590023 metJ Escherichia coli E24377A transcriptional repressor protein MetJ YP_001465436.1 4462454 R 331111 CDS YP_001465437.1 157159075 5586065 4463048..4464208 1 NC_009801.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4464208 metB 5586065 metB Escherichia coli E24377A cystathionine gamma-synthase YP_001465437.1 4463048 D 331111 CDS YP_001465438.1 157158415 5586852 4464211..4466643 1 NC_009801.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4466643 metL 5586852 metL Escherichia coli E24377A bifunctional aspartate kinase II/homoserine dehydrogenase II YP_001465438.1 4464211 D 331111 CDS YP_001465439.1 157157250 5589665 4466992..4467882 1 NC_009801.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4467882 metF 5589665 metF Escherichia coli E24377A 5,10-methylenetetrahydrofolate reductase YP_001465439.1 4466992 D 331111 CDS YP_001465440.1 157158338 5590644 4468211..4470391 1 NC_009801.1 identified by similarity to SP:P13029; match to protein family HMM PF00141; match to protein family HMM TIGR00198; catalase/peroxidase HPI 4470391 katG 5590644 katG Escherichia coli E24377A catalase/peroxidase HPI YP_001465440.1 4468211 D 331111 CDS YP_001465441.1 157155201 5590466 4470485..4471390 1 NC_009801.1 identified by similarity to SP:P0ABT8; match to protein family HMM PF00892; transporter 4471390 5590466 EcE24377A_4483 Escherichia coli E24377A transporter YP_001465441.1 4470485 D 331111 CDS YP_001465442.1 157155885 5587677 complement(4471417..4472034) 1 NC_009801.1 identified by similarity to GB:AAZ90633.1; match to protein family HMM PF06940; hypothetical protein 4472034 5587677 EcE24377A_4484 Escherichia coli E24377A hypothetical protein YP_001465442.1 4471417 R 331111 CDS YP_001465443.1 157156368 5587967 complement(4472309..4473412) 1 NC_009801.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 4473412 gldA 5587967 gldA Escherichia coli E24377A glycerol dehydrogenase YP_001465443.1 4472309 R 331111 CDS YP_001465444.1 157156895 5590076 complement(4473423..4474085) 1 NC_009801.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 4474085 fsaB 5590076 fsaB Escherichia coli E24377A fructose-6-phosphate aldolase YP_001465444.1 4473423 R 331111 CDS YP_001465445.1 157156963 5586169 complement(4474097..4476598) 1 NC_009801.1 identified by similarity to SP:P32670; match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; multi-phosphoryl transfer protein 2 4476598 ptsA 5586169 ptsA Escherichia coli E24377A multi-phosphoryl transfer protein 2 YP_001465445.1 4474097 R 331111 CDS YP_001465446.1 157157913 5590480 4476907..4477986 1 NC_009801.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 4477986 5590480 EcE24377A_4488 Escherichia coli E24377A fructose-like permease EIIC subunit 2 YP_001465446.1 4476907 D 331111 CDS YP_001465447.1 157158562 5586345 4478001..4478321 1 NC_009801.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; PTS system fructose-like transporter subunit EIIB 4478321 5586345 EcE24377A_4489 Escherichia coli E24377A PTS system fructose-like transporter subunit EIIB YP_001465447.1 4478001 D 331111 CDS YP_001465448.1 157158917 5589713 4478372..4480669 1 NC_009801.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 4480669 pflD 5589713 pflD Escherichia coli E24377A formate acetyltransferase 2 YP_001465448.1 4478372 D 331111 CDS YP_001465449.1 157154749 5590566 4480635..4481513 1 NC_009801.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494; pyruvate formate lyase II activase 4481513 5590566 EcE24377A_4491 Escherichia coli E24377A pyruvate formate lyase II activase YP_001465449.1 4480635 D 331111 CDS YP_001465450.1 157157726 5587066 4481515..4481856 1 NC_009801.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 4481856 5587066 EcE24377A_4493 Escherichia coli E24377A fructose-like phosphotransferase EIIB subunit 3 YP_001465450.1 4481515 D 331111 CDS YP_001465451.1 157157214 5589048 complement(4481843..4482694) 1 NC_009801.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 4482694 5589048 EcE24377A_4492 Escherichia coli E24377A AraC family transcriptional regulator YP_001465451.1 4481843 R 331111 CDS YP_001465452.1 157157305 5586271 complement(4482843..4484576) 1 NC_009801.1 identified by match to protein family HMM PF00884; hypothetical protein 4484576 5586271 EcE24377A_4494 Escherichia coli E24377A hypothetical protein YP_001465452.1 4482843 R 331111 CDS YP_001465453.1 157159345 5586747 complement(4484759..4487410) 1 NC_009801.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 4487410 ppc 5586747 ppc Escherichia coli E24377A phosphoenolpyruvate carboxylase YP_001465453.1 4484759 R 331111 CDS YP_001465454.1 157158301 5588158 complement(4487762..4488913) 1 NC_009801.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 4488913 argE 5588158 argE Escherichia coli E24377A acetylornithine deacetylase YP_001465454.1 4487762 R 331111 CDS YP_001465455.1 157155914 5589679 4489067..4490071 1 NC_009801.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4490071 argC 5589679 argC Escherichia coli E24377A N-acetyl-gamma-glutamyl-phosphate reductase YP_001465455.1 4489067 D 331111 CDS YP_001465456.1 157155203 5588239 4490082..4490855 1 NC_009801.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4490855 argB 5588239 argB Escherichia coli E24377A acetylglutamate kinase YP_001465456.1 4490082 D 331111 CDS YP_001465457.1 157156952 5587646 4490916..4492289 1 NC_009801.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4492289 argH 5587646 argH Escherichia coli E24377A argininosuccinate lyase YP_001465457.1 4490916 D 331111 CDS YP_001465458.1 157156307 5590245 4492787..4494001 1 NC_009801.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746; starvation sensing protein 4494001 rspA2 5590245 rspA2 Escherichia coli E24377A starvation sensing protein YP_001465458.1 4492787 D 331111 CDS YP_001465459.1 157155164 5587717 4494068..4495351 1 NC_009801.1 identified by match to protein family HMM PF07690; phthalate permease 4495351 5587717 EcE24377A_4501 Escherichia coli E24377A phthalate permease YP_001465459.1 4494068 D 331111 CDS YP_001465460.1 157159132 5587079 4495602..4496519 1 NC_009801.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4496519 oxyR 5587079 oxyR Escherichia coli E24377A DNA-binding transcriptional regulator OxyR YP_001465460.1 4495602 D 331111 CDS YP_001465461.1 157158861 5587637 complement(4496502..4497902) 1 NC_009801.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 4497902 sthA 5587637 sthA Escherichia coli E24377A soluble pyridine nucleotide transhydrogenase YP_001465461.1 4496502 R 331111 CDS YP_001465462.1 157158291 5587480 4498236..4498883 1 NC_009801.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4498883 fabR 5587480 fabR Escherichia coli E24377A DNA-binding transcriptional repressor FabR YP_001465462.1 4498236 D 331111 CDS YP_001465463.1 157155654 5589535 4498883..4499242 1 NC_009801.1 identified by match to protein family HMM PF07226; hypothetical protein 4499242 5589535 EcE24377A_4505 Escherichia coli E24377A hypothetical protein YP_001465463.1 4498883 D 331111 CDS YP_001465464.1 157155127 5588094 complement(4499282..4500382) 1 NC_009801.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 4500382 trmA 5588094 trmA Escherichia coli E24377A tRNA (uracil-5-)-methyltransferase YP_001465464.1 4499282 R 331111 CDS YP_001465465.1 157157589 5586885 4500751..4502595 1 NC_009801.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4502595 btuB 5586885 btuB Escherichia coli E24377A vitamin B12/cobalamin outer membrane transporter YP_001465465.1 4500751 D 331111 CDS YP_001465466.1 157157092 5587187 4502540..4503397 1 NC_009801.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4503397 murI 5587187 murI Escherichia coli E24377A glutamate racemase YP_001465466.1 4502540 D 331111 CDS YP_001465467.1 157158153 5589351 4509083..4510111 1 NC_009801.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4510111 murB 5589351 murB Escherichia coli E24377A UDP-N-acetylenolpyruvoylglucosamine reductase YP_001465467.1 4509083 D 331111 CDS YP_001465468.1 157156012 5589743 4510108..4511073 1 NC_009801.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4511073 birA 5589743 birA Escherichia coli E24377A biotin--protein ligase YP_001465468.1 4510108 D 331111 CDS YP_001465469.1 157156398 5587359 complement(4511102..4512052) 1 NC_009801.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 4512052 coaA 5587359 coaA Escherichia coli E24377A pantothenate kinase YP_001465469.1 4511102 R 331111 CDS YP_001465470.1 157159350 5585902 complement(4512109..4512270) 1 NC_009801.1 identified by glimmer; hypothetical protein 4512270 5585902 EcE24377A_4514 Escherichia coli E24377A hypothetical protein YP_001465470.1 4512109 R 331111 CDS YP_001465471.1 157158302 5586136 4512970..4514154 1 NC_009801.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4514154 tuf2 5586136 tuf2 Escherichia coli E24377A elongation factor Tu YP_001465471.1 4512970 D 331111 CDS YP_001465472.1 157155377 5589680 4514384..4514767 1 NC_009801.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4514767 secE 5589680 secE Escherichia coli E24377A preprotein translocase subunit SecE YP_001465472.1 4514384 D 331111 CDS YP_001465473.1 157154871 5589655 4514769..4515314 1 NC_009801.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4515314 nusG 5589655 nusG Escherichia coli E24377A transcription antitermination protein NusG YP_001465473.1 4514769 D 331111 CDS YP_001465474.1 157156820 5590043 complement(4515419..4516420) 1 NC_009801.1 identified by similarity to GB:AAN83366.1; hypothetical protein 4516420 5590043 EcE24377A_4522 Escherichia coli E24377A hypothetical protein YP_001465474.1 4515419 R 331111 CDS YP_001465475.1 157155677 5586405 4515473..4515901 1 NC_009801.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4515901 rplK 5586405 rplK Escherichia coli E24377A 50S ribosomal protein L11 YP_001465475.1 4515473 D 331111 CDS YP_001465476.1 157157546 5586349 4515905..4516609 1 NC_009801.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4516609 rplA 5586349 rplA Escherichia coli E24377A 50S ribosomal protein L1 YP_001465476.1 4515905 D 331111 CDS YP_001465477.1 157156972 5587474 4517022..4517519 1 NC_009801.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4517519 rplJ 5587474 rplJ Escherichia coli E24377A 50S ribosomal protein L10 YP_001465477.1 4517022 D 331111 CDS YP_001465478.1 157155113 5589253 complement(4517571..4518077) 1 NC_009801.1 identified by glimmer; hypothetical protein 4518077 5589253 EcE24377A_4526 Escherichia coli E24377A hypothetical protein YP_001465478.1 4517571 R 331111 CDS YP_001465479.1 157156657 5587845 4517586..4517951 1 NC_009801.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4517951 rplL 5587845 rplL Escherichia coli E24377A 50S ribosomal protein L7/L12 YP_001465479.1 4517586 D 331111 CDS YP_001465480.1 157155952 5590109 4518271..4522299 1 NC_009801.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4522299 rpoB 5590109 rpoB Escherichia coli E24377A DNA-directed RNA polymerase subunit beta YP_001465480.1 4518271 D 331111 CDS YP_001465481.1 157156616 5589321 4522376..4526599 1 NC_009801.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4526599 rpoC 5589321 rpoC Escherichia coli E24377A DNA-directed RNA polymerase subunit beta' YP_001465481.1 4522376 D 331111 CDS YP_001465482.1 157159389 5590774 4526812..4527351 1 NC_009801.1 identified by similarity to SP:P27375; heat shock protein 4527351 htrC 5590774 htrC Escherichia coli E24377A heat shock protein YP_001465482.1 4526812 D 331111 CDS YP_001465483.1 157157692 5586259 complement(4527761..4528894) 1 NC_009801.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 4528894 thiH 5586259 thiH Escherichia coli E24377A thiamine biosynthesis protein ThiH YP_001465483.1 4527761 R 331111 CDS YP_001465484.1 157155658 5587209 complement(4528891..4529661) 1 NC_009801.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 4529661 thiG 5587209 thiG Escherichia coli E24377A thiazole synthase YP_001465484.1 4528891 R 331111 CDS YP_001465485.1 157158468 5588279 complement(4529663..4529863) 1 NC_009801.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 4529863 thiS 5588279 thiS Escherichia coli E24377A sulfur carrier protein ThiS YP_001465485.1 4529663 R 331111 CDS YP_001465486.1 157156779 5587549 complement(4529847..4530602) 1 NC_009801.1 identified by similarity to SP:P30138; match to protein family HMM PF00899; match to protein family HMM PF05237; match to protein family HMM TIGR02356; thiazole biosynthesis adenylyltransferase ThiF 4530602 thiF 5587549 thiF Escherichia coli E24377A thiazole biosynthesis adenylyltransferase ThiF YP_001465486.1 4529847 R 331111 CDS YP_001465487.1 157154731 5589036 complement(4530595..4531230) 1 NC_009801.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 4531230 thiE 5589036 thiE Escherichia coli E24377A thiamine-phosphate pyrophosphorylase YP_001465487.1 4530595 R 331111 CDS YP_001465488.1 157159265 5590823 complement(4531230..4533125) 1 NC_009801.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 4533125 thiC 5590823 thiC Escherichia coli E24377A thiamine biosynthesis protein ThiC YP_001465488.1 4531230 R 331111 CDS YP_001465489.1 157157700 5587886 complement(4533358..4533834) 1 NC_009801.1 binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 4533834 rsd 5587886 rsd Escherichia coli E24377A anti-RNA polymerase sigma 70 factor YP_001465489.1 4533358 R 331111 CDS YP_001465490.1 157154966 5586636 4533929..4534702 1 NC_009801.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4534702 nudC 5586636 nudC Escherichia coli E24377A NADH pyrophosphatase YP_001465490.1 4533929 D 331111 CDS YP_001465491.1 157155476 5588718 complement(4534625..4534726) 1 NC_009801.1 identified by glimmer; hypothetical protein 4534726 5588718 EcE24377A_4538 Escherichia coli E24377A hypothetical protein YP_001465491.1 4534625 R 331111 CDS YP_001465492.1 157158608 5588505 4534742..4535806 1 NC_009801.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4535806 hemE 5588505 hemE Escherichia coli E24377A uroporphyrinogen decarboxylase YP_001465492.1 4534742 D 331111 CDS YP_001465493.1 157155667 5586902 4535816..4536487 1 NC_009801.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4536487 nfi 5586902 nfi Escherichia coli E24377A endonuclease V YP_001465493.1 4535816 D 331111 CDS YP_001465494.1 157158152 5590323 4536530..4537120 1 NC_009801.1 identified by match to protein family HMM PF04222; hypothetical protein 4537120 5590323 EcE24377A_4542 Escherichia coli E24377A hypothetical protein YP_001465494.1 4536530 D 331111 CDS YP_001465495.1 157157657 5589742 4537307..4537579 1 NC_009801.1 histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4537579 hupA 5589742 hupA Escherichia coli E24377A transcriptional regulator HU subunit alpha YP_001465495.1 4537307 D 331111 CDS YP_001465496.1 157156532 5586075 4537592..4538287 1 NC_009801.1 identified by match to protein family HMM PF07356; hypothetical protein 4538287 5586075 EcE24377A_4544 Escherichia coli E24377A hypothetical protein YP_001465496.1 4537592 D 331111 CDS YP_001465497.1 157156390 5590227 complement(4538289..4538714) 1 NC_009801.1 identified by similarity to SP:P0AAA9; zinc resistance protein 4538714 zraP 5590227 zraP Escherichia coli E24377A zinc resistance protein YP_001465497.1 4538289 R 331111 CDS YP_001465498.1 157157532 5586058 complement(4538717..4538845) 1 NC_009801.1 identified by glimmer; hypothetical protein 4538845 5586058 EcE24377A_4546 Escherichia coli E24377A hypothetical protein YP_001465498.1 4538717 R 331111 CDS YP_001465499.1 157157582 5588758 4538952..4540328 1 NC_009801.1 identified by similarity to SP:P14377; match to protein family HMM PF00512; match to protein family HMM PF02518; sensor protein ZraS 4540328 zraS 5588758 zraS Escherichia coli E24377A sensor protein ZraS YP_001465499.1 4538952 D 331111 CDS YP_001465500.1 157157738 5589970 4540325..4541650 1 NC_009801.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4541650 5589970 EcE24377A_4549 Escherichia coli E24377A transcriptional regulatory protein ZraR YP_001465500.1 4540325 D 331111 CDS YP_001465501.1 157156020 5590010 complement(4541647..4542936) 1 NC_009801.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 4542936 purD 5590010 purD Escherichia coli E24377A phosphoribosylamine--glycine ligase YP_001465501.1 4541647 R 331111 CDS YP_001465502.1 157156680 5588057 complement(4542948..4544537) 1 NC_009801.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4544537 purH 5588057 purH Escherichia coli E24377A bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_001465502.1 4542948 R 331111 CDS YP_001465503.1 157154991 5590420 4544655..4544777 1 NC_009801.1 identified by glimmer; hypothetical protein 4544777 5590420 EcE24377A_4551 Escherichia coli E24377A hypothetical protein YP_001465503.1 4544655 D 331111 CDS YP_001465504.1 157157102 5587134 complement(4550279..4550722) 1 NC_009801.1 identified by match to protein family HMM PF00583; hypothetical protein 4550722 5587134 EcE24377A_4554 Escherichia coli E24377A hypothetical protein YP_001465504.1 4550279 R 331111 CDS YP_001465505.1 157157205 5586756 4550879..4551808 1 NC_009801.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4551808 metA 5586756 metA Escherichia coli E24377A homoserine O-succinyltransferase YP_001465505.1 4550879 D 331111 CDS YP_001465506.1 157155521 5590326 4552077..4553678 1 NC_009801.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4553678 aceB 5590326 aceB Escherichia coli E24377A malate synthase YP_001465506.1 4552077 D 331111 CDS YP_001465507.1 157156017 5586010 4553708..4555012 1 NC_009801.1 identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346; isocitrate lyase 4555012 aceA 5586010 aceA Escherichia coli E24377A isocitrate lyase YP_001465507.1 4553708 D 331111 CDS YP_001465508.1 157159203 5586505 4555081..4555317 1 NC_009801.1 identified by glimmer; hypothetical protein 4555317 5586505 EcE24377A_4559 Escherichia coli E24377A hypothetical protein YP_001465508.1 4555081 D 331111 CDS YP_001465509.1 157158230 5590658 4555293..4557029 1 NC_009801.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase 4557029 aceK 5590658 aceK Escherichia coli E24377A bifunctional isocitrate dehydrogenase kinase/phosphatase YP_001465509.1 4555293 D 331111 CDS YP_001465510.1 157156537 5587800 complement(4556998..4558572) 1 NC_009801.1 identified by match to protein family HMM PF07906; ankyrin repeat-containing protein 4558572 arpA 5587800 arpA Escherichia coli E24377A ankyrin repeat-containing protein YP_001465510.1 4556998 R 331111 CDS YP_001465511.1 157155495 5586782 complement(4558890..4559714) 1 NC_009801.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator 4559714 iclR 5586782 iclR Escherichia coli E24377A IclR family transcriptional regulator YP_001465511.1 4558890 R 331111 CDS YP_001465512.1 157156072 5588461 4559914..4563597 1 NC_009801.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4563597 metH 5588461 metH Escherichia coli E24377A B12-dependent methionine synthase YP_001465512.1 4559914 D 331111 CDS YP_001465513.1 157158157 5586892 4563817..4565448 1 NC_009801.1 identified by match to protein family HMM PF02690; match to protein family HMM TIGR00704; match to protein family HMM TIGR01013; inorganic phosphate transporter sodium-dependent 4565448 pNaS 5586892 pNaS Escherichia coli E24377A inorganic phosphate transporter sodium-dependent YP_001465513.1 4563817 D 331111 CDS YP_001465514.1 157157812 5586146 complement(4565539..4566228) 1 NC_009801.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 4566228 pepE 5586146 pepE Escherichia coli E24377A peptidase E YP_001465514.1 4565539 R 331111 CDS YP_001465515.1 157156860 5589735 4566440..4567312 1 NC_009801.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4567312 rluF 5589735 rluF Escherichia coli E24377A 23S rRNA pseudouridine synthase F YP_001465515.1 4566440 D 331111 CDS YP_001465516.1 157157640 5589324 complement(4567313..4567585) 1 NC_009801.1 identified by similarity to GB:AAZ90700.1; hypothetical protein 4567585 5589324 EcE24377A_4567 Escherichia coli E24377A hypothetical protein YP_001465516.1 4567313 R 331111 CDS YP_001465517.1 157157211 5586240 4567830..4567991 1 NC_009801.1 identified by glimmer; hypothetical protein 4567991 5586240 EcE24377A_4568 Escherichia coli E24377A hypothetical protein YP_001465517.1 4567830 D 331111 CDS YP_001465518.1 157157698 5586192 4568115..4569242 1 NC_009801.1 identified by match to protein family HMM PF01145; hypothetical protein 4569242 5586192 EcE24377A_4569 Escherichia coli E24377A hypothetical protein YP_001465518.1 4568115 D 331111 CDS YP_001465519.1 157155765 5586634 4569275..4570039 1 NC_009801.1 identified by similarity to GB:CAD13753.1; hypothetical protein 4570039 5586634 EcE24377A_4570 Escherichia coli E24377A hypothetical protein YP_001465519.1 4569275 D 331111 CDS YP_001465520.1 157156038 5587939 complement(4570075..4571001) 1 NC_009801.1 identified by match to protein family HMM PF06414; zeta toxin 4571001 5587939 EcE24377A_4571 Escherichia coli E24377A zeta toxin YP_001465520.1 4570075 R 331111 CDS YP_001465521.1 157159252 5588331 complement(4571146..4572495) 1 NC_009801.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase 4572495 lysC 5588331 lysC Escherichia coli E24377A aspartate kinase YP_001465521.1 4571146 R 331111 CDS YP_001465522.1 157155242 5590015 4573020..4574669 1 NC_009801.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4574669 pgi 5590015 pgi Escherichia coli E24377A glucose-6-phosphate isomerase YP_001465522.1 4573020 D 331111 CDS YP_001465524.1 157156829 5587020 4575350..4576018 1 NC_009801.1 hypothetical protein 4576018 5587020 EcE24377A_4575 Escherichia coli E24377A hypothetical protein YP_001465524.1 4575350 D 331111 CDS YP_001465525.1 157155115 5586329 4576015..4576752 1 NC_009801.1 identified by match to protein family HMM PF06251; hypothetical protein 4576752 5586329 EcE24377A_4576 Escherichia coli E24377A hypothetical protein YP_001465525.1 4576015 D 331111 CDS YP_001465526.1 157156115 5587680 4576752..4578848 1 NC_009801.1 identified by match to protein family HMM PF06082; lipoprotein 4578848 5587680 EcE24377A_4577 Escherichia coli E24377A lipoprotein YP_001465526.1 4576752 D 331111 CDS YP_001465527.1 157158355 5588813 4578852..4579013 1 NC_009801.1 identified by glimmer; hypothetical protein 4579013 5588813 EcE24377A_4579 Escherichia coli E24377A hypothetical protein YP_001465527.1 4578852 D 331111 CDS YP_001465528.1 157159008 5587842 complement(4578895..4579173) 1 NC_009801.1 identified by similarity to GB:ABB68492.1; hypothetical protein 4579173 5587842 EcE24377A_4578 Escherichia coli E24377A hypothetical protein YP_001465528.1 4578895 R 331111 CDS YP_001465529.1 157155846 5586875 4579174..4579317 1 NC_009801.1 identified by glimmer; hypothetical protein 4579317 5586875 EcE24377A_4580 Escherichia coli E24377A hypothetical protein YP_001465529.1 4579174 D 331111 CDS YP_001465530.1 157155330 5587025 4579443..4579853 1 NC_009801.1 identified by match to protein family HMM PF06146; phosphate-starvation-inducible protein PsiE 4579853 psiE 5587025 psiE Escherichia coli E24377A phosphate-starvation-inducible protein PsiE YP_001465530.1 4579443 D 331111 CDS YP_001465531.1 157156030 5586709 complement(4579897..4581372) 1 NC_009801.1 xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter; D-xylose transporter XylE 4581372 xylE 5586709 xylE Escherichia coli E24377A D-xylose transporter XylE YP_001465531.1 4579897 R 331111 CDS YP_001465532.1 157156871 5587258 complement(4581744..4582634) 1 NC_009801.1 with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 4582634 malG 5587258 malG Escherichia coli E24377A maltose transporter permease YP_001465532.1 4581744 R 331111 CDS YP_001465533.1 157156470 5586830 complement(4582649..4584193) 1 NC_009801.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 4584193 malF 5586830 malF Escherichia coli E24377A maltose transporter membrane protein YP_001465533.1 4582649 R 331111 CDS YP_001465534.1 157154727 5589453 4584183..4584305 1 NC_009801.1 identified by glimmer; hypothetical protein 4584305 5589453 EcE24377A_4585 Escherichia coli E24377A hypothetical protein YP_001465534.1 4584183 D 331111 CDS YP_001465535.1 157156613 5587010 complement(4584347..4585537) 1 NC_009801.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 4585537 malE 5587010 malE Escherichia coli E24377A maltose ABC transporter periplasmic protein YP_001465535.1 4584347 R 331111 CDS YP_001465536.1 157156201 5590074 4585902..4587017 1 NC_009801.1 with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4587017 malK 5590074 malK Escherichia coli E24377A maltose/maltodextrin transporter ATP-binding protein YP_001465536.1 4585902 D 331111 CDS YP_001465537.1 157159111 5586483 4587089..4588429 1 NC_009801.1 porin involved in the transport of maltose and maltodextrins; maltoporin 4588429 lamB 5586483 lamB Escherichia coli E24377A maltoporin YP_001465537.1 4587089 D 331111 CDS YP_001465538.1 157157130 5587911 4588581..4589501 1 NC_009801.1 identified by match to protein family HMM PF07148; maltose regulon periplasmic protein 4589501 malM 5587911 malM Escherichia coli E24377A maltose regulon periplasmic protein YP_001465538.1 4588581 D 331111 CDS YP_001465539.1 157154721 5585991 complement(4589476..4589628) 1 NC_009801.1 identified by glimmer; hypothetical protein 4589628 5585991 EcE24377A_4589 Escherichia coli E24377A hypothetical protein YP_001465539.1 4589476 R 331111 CDS YP_001465540.1 157156469 5587370 4591532..4592029 1 NC_009801.1 catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4592029 ubiC 5587370 ubiC Escherichia coli E24377A chorismate pyruvate lyase YP_001465540.1 4591532 D 331111 CDS YP_001465541.1 157157014 5586134 4592042..4592914 1 NC_009801.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4592914 ubiA 5586134 ubiA Escherichia coli E24377A 4-hydroxybenzoate octaprenyltransferase YP_001465541.1 4592042 D 331111 CDS YP_001465542.1 157157568 5589291 complement(4593069..4595492) 1 NC_009801.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 4595492 plsB 5589291 plsB Escherichia coli E24377A glycerol-3-phosphate acyltransferase YP_001465542.1 4593069 R 331111 CDS YP_001465543.1 157158093 5588569 4595663..4596031 1 NC_009801.1 identified by similarity to SP:P0ABN1; match to protein family HMM PF01219; diacylglycerol kinase 4596031 dgkA 5588569 dgkA Escherichia coli E24377A diacylglycerol kinase YP_001465543.1 4595663 D 331111 CDS YP_001465544.1 157156057 5586165 4596141..4596749 1 NC_009801.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 4596749 lexA 5586165 lexA Escherichia coli E24377A LexA repressor YP_001465544.1 4596141 D 331111 CDS YP_001465545.1 157156587 5587556 4596768..4598147 1 NC_009801.1 identified by similarity to SP:P28303; match to protein family HMM PF01554; match to protein family HMM TIGR00797; DNA-damage-inducible SOS response protein 4598147 dinF 5587556 dinF Escherichia coli E24377A DNA-damage-inducible SOS response protein YP_001465545.1 4596768 D 331111 CDS YP_001465546.1 157158046 5587053 4598263..4598472 1 NC_009801.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; stress-response protein 4598472 5587053 EcE24377A_4598 Escherichia coli E24377A stress-response protein YP_001465546.1 4598263 D 331111 CDS YP_001465547.1 157158569 5590631 complement(4598514..4599029) 1 NC_009801.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor 4599029 zur 5590631 zur Escherichia coli E24377A zinc uptake transcriptional repressor YP_001465547.1 4598514 R 331111 CDS YP_001465548.1 157157830 5588721 4599347..4600369 1 NC_009801.1 hypothetical protein 4600369 5588721 EcE24377A_4600 Escherichia coli E24377A hypothetical protein YP_001465548.1 4599347 D 331111 CDS YP_001465549.1 157157144 5586878 4600727..4601770 1 NC_009801.1 identified by similarity to SP:P32695; match to protein family HMM PF01207; match to protein family HMM TIGR00742; tRNA-dihydrouridine synthase A 4601770 dusA 5586878 dusA Escherichia coli E24377A tRNA-dihydrouridine synthase A YP_001465549.1 4600727 D 331111 CDS YP_001465550.1 157159166 5589636 4601904..4602146 1 NC_009801.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4602146 pspG 5589636 pspG Escherichia coli E24377A phage shock protein G YP_001465550.1 4601904 D 331111 CDS YP_001465551.1 157158518 5588200 complement(4602312..4603295) 1 NC_009801.1 identified by similarity to SP:P28304; match to protein family HMM PF00107; match to protein family HMM PF08240; quinone oxidoreductase 4603295 qor 5588200 qor Escherichia coli E24377A quinone oxidoreductase YP_001465551.1 4602312 R 331111 CDS YP_001465552.1 157156324 5589268 4603378..4604793 1 NC_009801.1 unwinds double stranded DNA; replicative DNA helicase 4604793 dnaB 5589268 dnaB Escherichia coli E24377A replicative DNA helicase YP_001465552.1 4603378 D 331111 CDS YP_001465553.1 157157084 5588732 4604846..4605925 1 NC_009801.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4605925 alr 5588732 alr Escherichia coli E24377A alanine racemase YP_001465553.1 4604846 D 331111 CDS YP_001465554.1 157154936 5589525 4606178..4607371 1 NC_009801.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4607371 tyrB 5589525 tyrB Escherichia coli E24377A aromatic amino acid aminotransferase YP_001465554.1 4606178 D 331111 CDS YP_001465555.1 157155609 5587301 4608498..4609211 1 NC_009801.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4609211 aphA 5587301 aphA Escherichia coli E24377A acid phosphatase/phosphotransferase YP_001465555.1 4608498 D 331111 CDS YP_001465556.1 157158574 5587040 4609322..4609738 1 NC_009801.1 identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149; hypothetical protein 4609738 5587040 EcE24377A_4608 Escherichia coli E24377A hypothetical protein YP_001465556.1 4609322 D 331111 CDS YP_001465557.1 157155662 5588474 4609742..4610098 1 NC_009801.1 identified by match to protein family HMM PF04237; hypothetical protein 4610098 5588474 EcE24377A_4609 Escherichia coli E24377A hypothetical protein YP_001465557.1 4609742 D 331111 CDS YP_001465558.1 157157192 5587828 complement(4610133..4612955) 1 NC_009801.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 4612955 uvrA 5587828 uvrA Escherichia coli E24377A excinuclease ABC subunit A YP_001465558.1 4610133 R 331111 CDS YP_001465559.1 157158944 5586396 4613209..4613745 1 NC_009801.1 binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4613745 ssb 5586396 ssb Escherichia coli E24377A single-stranded DNA-binding protein YP_001465559.1 4613209 D 331111 CDS YP_001465560.1 157156421 5587292 4613785..4613880 1 NC_009801.1 identified by glimmer; hypothetical protein 4613880 5587292 EcE24377A_4613 Escherichia coli E24377A hypothetical protein YP_001465560.1 4613785 D 331111 CDS YP_001465561.1 157157091 5588338 complement(4613844..4614125) 1 NC_009801.1 hypothetical protein 4614125 5588338 EcE24377A_4612 Escherichia coli E24377A hypothetical protein YP_001465561.1 4613844 R 331111 CDS YP_001465562.1 157157528 5587813 4614555..4616141 1 NC_009801.1 identified by match to protein family HMM PF00563; cyclic diguanylate phosphodiesterase domain-containing protein 4616141 5587813 EcE24377A_4614 Escherichia coli E24377A cyclic diguanylate phosphodiesterase domain-containing protein YP_001465562.1 4614555 D 331111 CDS YP_001465563.1 157158050 5589514 complement(4616144..4616467) 1 NC_009801.1 regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS 4616467 soxS 5589514 soxS Escherichia coli E24377A DNA-binding transcriptional regulator SoxS YP_001465563.1 4616144 R 331111 CDS YP_001465564.1 157156684 5587103 4616553..4617017 1 NC_009801.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR01950; redox-sensitive transcriptional activator SoxR 4617017 soxR 5587103 soxR Escherichia coli E24377A redox-sensitive transcriptional activator SoxR YP_001465564.1 4616553 D 331111 CDS YP_001465565.1 157154789 5586691 complement(4617220..4617333) 1 NC_009801.1 identified by glimmer; hypothetical protein 4617333 5586691 EcE24377A_4617 Escherichia coli E24377A hypothetical protein YP_001465565.1 4617220 R 331111 CDS YP_001465566.1 157157581 5587688 complement(4617308..4617526) 1 NC_009801.1 identified by glimmer; hypothetical protein 4617526 5587688 EcE24377A_4618 Escherichia coli E24377A hypothetical protein YP_001465566.1 4617308 R 331111 CDS YP_001465567.1 157158784 5589014 4617563..4618912 1 NC_009801.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; sulfate permease inorganic anion transporter 4618912 5589014 EcE24377A_4619 Escherichia coli E24377A sulfate permease inorganic anion transporter YP_001465567.1 4617563 D 331111 CDS YP_001465568.1 157158290 5587217 4619063..4620712 1 NC_009801.1 identified by match to protein family HMM PF00999; match to protein family HMM TIGR00831; Na+/H+ antiporter 4620712 5587217 EcE24377A_4620 Escherichia coli E24377A Na+/H+ antiporter YP_001465568.1 4619063 D 331111 CDS YP_001465569.1 157158802 5590413 complement(4620866..4622158) 1 NC_009801.1 identified by match to protein family HMM PF00805; pentapeptide repeat-containing protein 4622158 5590413 EcE24377A_4621 Escherichia coli E24377A pentapeptide repeat-containing protein YP_001465569.1 4620866 R 331111 CDS YP_001465570.1 157158113 5588674 complement(4622336..4623985) 1 NC_009801.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease 4623985 actP 5588674 actP Escherichia coli E24377A acetate permease YP_001465570.1 4622336 R 331111 CDS YP_001465571.1 157157484 5586175 complement(4623982..4624296) 1 NC_009801.1 identified by match to protein family HMM PF04341; hypothetical protein 4624296 5586175 EcE24377A_4623 Escherichia coli E24377A hypothetical protein YP_001465571.1 4623982 R 331111 CDS YP_001465572.1 157158352 5589892 complement(4624296..4624424) 1 NC_009801.1 identified by glimmer; hypothetical protein 4624424 5589892 EcE24377A_4624 Escherichia coli E24377A hypothetical protein YP_001465572.1 4624296 R 331111 CDS YP_001465573.1 157159006 5587364 complement(4624496..4626454) 1 NC_009801.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4626454 acsA 5587364 acsA Escherichia coli E24377A acetyl-CoA synthetase YP_001465573.1 4624496 R 331111 CDS YP_001465574.1 157157304 5586873 4626846..4628282 1 NC_009801.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4628282 nrfA 5586873 nrfA Escherichia coli E24377A cytochrome c552 YP_001465574.1 4626846 D 331111 CDS YP_001465575.1 157158053 5586746 4628327..4628893 1 NC_009801.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4628893 nrfB 5586746 nrfB Escherichia coli E24377A cytochrome c nitrite reductase pentaheme subunit YP_001465575.1 4628327 D 331111 CDS YP_001465576.1 157157837 5586157 4628890..4629561 1 NC_009801.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409; match to protein family HMM TIGR03149; cytochrome c nitrite reductase, Fe-S protein 4629561 nrfC 5586157 nrfC Escherichia coli E24377A cytochrome c nitrite reductase, Fe-S protein YP_001465576.1 4628890 D 331111 CDS YP_001465577.1 157156178 5588917 4629558..4630514 1 NC_009801.1 identified by match to protein family HMM PF03916; match to protein family HMM TIGR03148; nrfD protein 4630514 nrfD 5588917 nrfD Escherichia coli E24377A nrfD protein YP_001465577.1 4629558 D 331111 CDS YP_001465578.1 157158945 5589257 4630594..4632252 1 NC_009801.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4632252 nrfE 5589257 nrfE Escherichia coli E24377A heme lyase subunit NrfE YP_001465578.1 4630594 D 331111 CDS YP_001465579.1 157157232 5586388 4632245..4632628 1 NC_009801.1 identified by similarity to SP:P32711; match to protein family HMM PF03918; match to protein family HMM TIGR03147; formate-dependent nitrite reductase complex subunit NrfF 4632628 nrfF 5586388 nrfF Escherichia coli E24377A formate-dependent nitrite reductase complex subunit NrfF YP_001465579.1 4632245 D 331111 CDS YP_001465580.1 157155160 5586416 4632625..4633221 1 NC_009801.1 identified by similarity to SP:P32712; match to protein family HMM PF00515; match to protein family HMM PF07719; formate-dependent nitrite reductase complex subunit NrfG 4633221 nrfG 5586416 nrfG Escherichia coli E24377A formate-dependent nitrite reductase complex subunit NrfG YP_001465580.1 4632625 D 331111 CDS YP_001465581.1 157155904 5587047 4633563..4634876 1 NC_009801.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4634876 gltP 5587047 gltP Escherichia coli E24377A glutamate/aspartate:proton symporter YP_001465581.1 4633563 D 331111 CDS YP_001465582.1 157159086 5586548 complement(4634954..4635643) 1 NC_009801.1 identified by match to protein family HMM PF08238; Sel1 repeat-containing protein 4635643 5586548 EcE24377A_4634 Escherichia coli E24377A Sel1 repeat-containing protein YP_001465582.1 4634954 R 331111 CDS YP_001465583.1 157158581 5588182 complement(4635737..4637416) 1 NC_009801.1 identified by similarity to SP:P07658; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01591; formate dehydrogenase H subunit alpha, selenocysteine-containing 4637416 fdhF 5588182 fdhF Escherichia coli E24377A formate dehydrogenase H subunit alpha, selenocysteine-containing YP_001465583.1 4635737 R 331111 CDS YP_001465584.1 157158827 5586028 complement(4638082..4639548) 1 NC_009801.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP 4639548 5586028 EcE24377A_4637 Escherichia coli E24377A outer membrane efflux protein MdtP YP_001465584.1 4638082 R 331111 CDS YP_001465585.1 157158319 5585952 complement(4639545..4641596) 1 NC_009801.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO 4641596 mdtO 5585952 mdtO Escherichia coli E24377A multidrug efflux system protein MdtO YP_001465585.1 4639545 R 331111 CDS YP_001465586.1 157155772 5587461 complement(4641596..4642627) 1 NC_009801.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN 4642627 mdtN 5587461 mdtN Escherichia coli E24377A multidrug resistance protein MdtN YP_001465586.1 4641596 R 331111 CDS YP_001465587.1 157156611 5586149 complement(4642646..4642969) 1 NC_009801.1 hypothetical protein 4642969 5586149 EcE24377A_4640 Escherichia coli E24377A hypothetical protein YP_001465587.1 4642646 R 331111 CDS YP_001465588.1 157155027 5589993 complement(4643130..4645115) 1 NC_009801.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase superfamily protein 4645115 5589993 EcE24377A_4641 Escherichia coli E24377A metallo-beta-lactamase superfamily protein YP_001465588.1 4643130 R 331111 CDS YP_001465589.1 157155553 5589959 4645309..4645476 1 NC_009801.1 identified by glimmer; hypothetical protein 4645476 5589959 EcE24377A_4642 Escherichia coli E24377A hypothetical protein YP_001465589.1 4645309 D 331111 CDS YP_001465590.1 157156828 5588288 4645754..4646083 1 NC_009801.1 identified by similarity to GB:AAZ90762.1; hypothetical protein 4646083 5588288 EcE24377A_4645 Escherichia coli E24377A hypothetical protein YP_001465590.1 4645754 D 331111 CDS YP_001465591.1 157156446 5589617 complement(4646230..4646988) 1 NC_009801.1 required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein 4646988 phnP 5589617 phnP Escherichia coli E24377A carbon-phosphorus lyase complex accessory protein YP_001465591.1 4646230 R 331111 CDS YP_001465592.1 157158056 5587488 complement(4646990..4647424) 1 NC_009801.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase 4647424 5587488 EcE24377A_4647 Escherichia coli E24377A aminoalkylphosphonic acid N-acetyltransferase YP_001465592.1 4646990 R 331111 CDS YP_001465593.1 157157976 5586939 complement(4647411..4647968) 1 NC_009801.1 identified by match to protein family HMM TIGR02322; ribose 1,5-bisphosphokinase 4647968 phnN 5586939 phnN Escherichia coli E24377A ribose 1,5-bisphosphokinase YP_001465593.1 4647411 R 331111 CDS YP_001465594.1 157159054 5587525 complement(4647968..4649104) 1 NC_009801.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR02318; phosphonate metabolism protein PhnM 4649104 phnM 5587525 phnM Escherichia coli E24377A phosphonate metabolism protein PhnM YP_001465594.1 4647968 R 331111 CDS YP_001465595.1 157157230 5586490 complement(4649101..4649781) 1 NC_009801.1 identified by similarity to SP:P16679; match to protein family HMM PF00005; match to protein family HMM TIGR02324; phosphonate C-P lyase system protein PhnL 4649781 phnL 5586490 phnL Escherichia coli E24377A phosphonate C-P lyase system protein PhnL YP_001465595.1 4649101 R 331111 CDS YP_001465596.1 157155315 5590141 complement(4649892..4650650) 1 NC_009801.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02323; phosphonate C-P lyase system protein PhnK 4650650 phnK 5590141 phnK Escherichia coli E24377A phosphonate C-P lyase system protein PhnK YP_001465596.1 4649892 R 331111 CDS YP_001465597.1 157158826 5586432 complement(4650647..4651492) 1 NC_009801.1 identified by match to protein family HMM PF06007; phosphonate metabolism protein PhnJ 4651492 phnJ 5586432 phnJ Escherichia coli E24377A phosphonate metabolism protein PhnJ YP_001465597.1 4650647 R 331111 CDS YP_001465598.1 157155144 5585951 complement(4651485..4652549) 1 NC_009801.1 identified by match to protein family HMM PF05861; phosphonate metabolism protein PhnI 4652549 phnI 5585951 phnI Escherichia coli E24377A phosphonate metabolism protein PhnI YP_001465598.1 4651485 R 331111 CDS YP_001465599.1 157155684 5589164 complement(4652549..4653133) 1 NC_009801.1 identified by match to protein family HMM PF05845; carbon-phosphorus lyase complex subunit 4653133 phnH 5589164 phnH Escherichia coli E24377A carbon-phosphorus lyase complex subunit YP_001465599.1 4652549 R 331111 CDS YP_001465600.1 157156248 5589220 complement(4653130..4653582) 1 NC_009801.1 identified by match to protein family HMM PF06754; match to protein family HMM TIGR03293; phosphonate C-P lyase system protein PhnG 4653582 phnG 5589220 phnG Escherichia coli E24377A phosphonate C-P lyase system protein PhnG YP_001465600.1 4653130 R 331111 CDS YP_001465601.1 157156155 5586384 complement(4653583..4654308) 1 NC_009801.1 may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF 4654308 phnF 5586384 phnF Escherichia coli E24377A phosphonate metabolism transcriptional regulator PhnF YP_001465601.1 4653583 R 331111 CDS YP_001465602.1 157157797 5585925 complement(4654329..4655108) 1 NC_009801.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01097; phosphonate ABC transporter permease 4655108 phnE 5585925 phnE Escherichia coli E24377A phosphonate ABC transporter permease YP_001465602.1 4654329 R 331111 CDS YP_001465603.1 157159457 5589008 complement(4655233..4656249) 1 NC_009801.1 identified by match to protein family HMM TIGR01098; match to protein family HMM TIGR03431; phosphonate ABC transporter periplasmic phosphonate-binding protein 4656249 phnD 5589008 phnD Escherichia coli E24377A phosphonate ABC transporter periplasmic phosphonate-binding protein YP_001465603.1 4655233 R 331111 CDS YP_001465604.1 157158129 5590869 complement(4656274..4657062) 1 NC_009801.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02315; phosphonate/organophosphate ester transporter subunit 4657062 phnC 5590869 phnC Escherichia coli E24377A phosphonate/organophosphate ester transporter subunit YP_001465604.1 4656274 R 331111 CDS YP_001465605.1 157157462 5586044 4657000..4657110 1 NC_009801.1 identified by glimmer; hypothetical protein 4657110 5586044 EcE24377A_4660 Escherichia coli E24377A hypothetical protein YP_001465605.1 4657000 D 331111 CDS YP_001465606.1 157156789 5586068 complement(4657195..4657638) 1 NC_009801.1 identified by similarity to SP:P16681; match to protein family HMM PF00903; hypothetical protein 4657638 5586068 EcE24377A_4661 Escherichia coli E24377A hypothetical protein YP_001465606.1 4657195 R 331111 CDS YP_001465607.1 157156127 5588431 complement(4657798..4658133) 1 NC_009801.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686; hypothetical protein 4658133 phnA 5588431 phnA Escherichia coli E24377A hypothetical protein YP_001465607.1 4657798 R 331111 CDS YP_001465608.1 157158501 5586478 4658535..4660763 1 NC_009801.1 hypothetical protein 4660763 5586478 EcE24377A_4663 Escherichia coli E24377A hypothetical protein YP_001465608.1 4658535 D 331111 CDS YP_001465609.1 157155427 5588618 4660793..4661638 1 NC_009801.1 hypothetical protein 4661638 5588618 EcE24377A_4664 Escherichia coli E24377A hypothetical protein YP_001465609.1 4660793 D 331111 CDS YP_001465610.1 157157151 5588284 4661902..4663404 1 NC_009801.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM PF08946; match to protein family HMM TIGR00883; proline/glycine betaine transporter 4663404 proP 5588284 proP Escherichia coli E24377A proline/glycine betaine transporter YP_001465610.1 4661902 D 331111 CDS YP_001465611.1 157158836 5588987 complement(4663581..4664672) 1 NC_009801.1 identified by similarity to SP:P30844; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor protein BasS/PmrB 4664672 basS 5588987 basS Escherichia coli E24377A sensor protein BasS/PmrB YP_001465611.1 4663581 R 331111 CDS YP_001465612.1 157158920 5585917 complement(4664682..4665350) 1 NC_009801.1 response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR 4665350 basR 5585917 basR Escherichia coli E24377A DNA-binding transcriptional regulator BasR YP_001465612.1 4664682 R 331111 CDS YP_001465613.1 157157656 5589907 complement(4665347..4667020) 1 NC_009801.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein 4667020 5589907 EcE24377A_4668 Escherichia coli E24377A cell division protein YP_001465613.1 4665347 R 331111 CDS YP_001465614.1 157154776 5586074 complement(4667094..4668431) 1 NC_009801.1 identified by similarity to SP:P60061; match to protein family HMM PF00324; arginine:agmatin antiporter 4668431 adiC 5586074 adiC Escherichia coli E24377A arginine:agmatin antiporter YP_001465614.1 4667094 R 331111 CDS YP_001465615.1 157155453 5586706 complement(4668568..4669329) 1 NC_009801.1 identified by similarity to GB:AAB18143.1; match to protein family HMM PF00165; transcriptional regulator AdiY 4669329 adiY 5586706 adiY Escherichia coli E24377A transcriptional regulator AdiY YP_001465615.1 4668568 R 331111 CDS YP_001465616.1 157156125 5588864 complement(4669654..4671924) 1 NC_009801.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; biodegradative arginine decarboxylase 4671924 adiA 5588864 adiA Escherichia coli E24377A biodegradative arginine decarboxylase YP_001465616.1 4669654 R 331111 CDS YP_001465617.1 157156790 5586541 complement(4672120..4673028) 1 NC_009801.1 identified by similarity to SP:P0ACH8; match to protein family HMM PF00165; DNA-binding transcriptional regulator MelR 4673028 melR 5586541 melR Escherichia coli E24377A DNA-binding transcriptional regulator MelR YP_001465617.1 4672120 R 331111 CDS YP_001465618.1 157156414 5590121 4673311..4674666 1 NC_009801.1 identified by similarity to SP:P06720; match to protein family HMM PF02056; alpha-galactosidase 4674666 melA 5590121 melA Escherichia coli E24377A alpha-galactosidase YP_001465618.1 4673311 D 331111 CDS YP_001465619.1 157156889 5589204 4674769..4676190 1 NC_009801.1 identified by similarity to SP:P02921; match to protein family HMM TIGR00792; melibiose:sodium symporter 4676190 melB 5589204 melB Escherichia coli E24377A melibiose:sodium symporter YP_001465619.1 4674769 D 331111 CDS YP_001465620.1 157157122 5588663 complement(4676329..4676958) 1 NC_009801.1 hypothetical protein 4676958 5588663 EcE24377A_4675 Escherichia coli E24377A hypothetical protein YP_001465620.1 4676329 R 331111 CDS YP_001465621.1 157158208 5590873 complement(4677081..4678727) 1 NC_009801.1 identified by similarity to SP:P14407; match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723; fumarate hydratase 4678727 fumB 5590873 fumB Escherichia coli E24377A fumarate hydratase YP_001465621.1 4677081 R 331111 CDS YP_001465622.1 157156674 5588082 complement(4680716..4681435) 1 NC_009801.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR 4681435 dcuR 5588082 dcuR Escherichia coli E24377A DNA-binding transcriptional activator DcuR YP_001465622.1 4680716 R 331111 CDS YP_001465623.1 157154941 5590515 complement(4681432..4683063) 1 NC_009801.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS 4683063 dcuS 5590515 dcuS Escherichia coli E24377A sensory histidine kinase DcuS YP_001465623.1 4681432 R 331111 CDS YP_001465624.1 157157680 5586361 4683244..4683474 1 NC_009801.1 identified by match to protein family HMM PF06902; hypothetical protein 4683474 5586361 EcE24377A_4680 Escherichia coli E24377A hypothetical protein YP_001465624.1 4683244 D 331111 CDS YP_001465625.1 157158181 5590551 4683486..4683758 1 NC_009801.1 hypothetical protein 4683758 5590551 EcE24377A_4681 Escherichia coli E24377A hypothetical protein YP_001465625.1 4683486 D 331111 CDS YP_001465626.1 157157649 5586524 4683985..4684281 1 NC_009801.1 identified by glimmer; hypothetical protein 4684281 5586524 EcE24377A_4682 Escherichia coli E24377A hypothetical protein YP_001465626.1 4683985 D 331111 CDS YP_001465627.1 157158143 5587382 4684309..4684482 1 NC_009801.1 identified by similarity to GB:AAV77221.1; hypothetical protein 4684482 5587382 EcE24377A_4683 Escherichia coli E24377A hypothetical protein YP_001465627.1 4684309 D 331111 CDS YP_001465628.1 157158511 5590829 complement(4684601..4686118) 1 NC_009801.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 4686118 lysS2 5590829 lysS2 Escherichia coli E24377A lysyl-tRNA synthetase YP_001465628.1 4684601 R 331111 CDS YP_001465629.1 157159332 5589283 complement(4686355..4687812) 1 NC_009801.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; amino acid/peptide transporter 4687812 5589283 EcE24377A_4685 Escherichia coli E24377A amino acid/peptide transporter YP_001465629.1 4686355 R 331111 CDS YP_001465630.1 157157750 5590562 complement(4687871..4690018) 1 NC_009801.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711; lysine decarboxylase-like protein, constitutive 4690018 5590562 EcE24377A_4686 Escherichia coli E24377A lysine decarboxylase-like protein, constitutive YP_001465630.1 4687871 R 331111 CDS YP_001465631.1 157156063 5588715 complement(4690098..4691432) 1 NC_009801.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 4691432 cadB 5588715 cadB Escherichia coli E24377A lysine/cadaverine antiporter YP_001465631.1 4690098 R 331111 CDS YP_001465632.1 157155632 5587535 complement(4691798..4693336) 1 NC_009801.1 regulates the cadBA operon; DNA-binding transcriptional activator CadC 4693336 cadC 5587535 cadC Escherichia coli E24377A DNA-binding transcriptional activator CadC YP_001465632.1 4691798 R 331111 CDS YP_001465633.1 157159148 5588355 complement(4694135..4694710) 1 NC_009801.1 identified by match to protein family HMM PF00440; transcriptional regulator 4694710 5588355 EcE24377A_4690 Escherichia coli E24377A transcriptional regulator YP_001465633.1 4694135 R 331111 CDS YP_001465634.1 157157307 5589721 complement(4694747..4696444) 1 NC_009801.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 4696444 dipZ 5589721 dipZ Escherichia coli E24377A thiol:disulfide interchange protein YP_001465634.1 4694747 R 331111 CDS YP_001465635.1 157157801 5586008 complement(4696420..4696758) 1 NC_009801.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA 4696758 cutA 5586008 cutA Escherichia coli E24377A divalent-cation tolerance protein CutA YP_001465635.1 4696420 R 331111 CDS YP_001465636.1 157156434 5589624 complement(4696874..4698175) 1 NC_009801.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 4698175 dcuA 5589624 dcuA Escherichia coli E24377A anaerobic C4-dicarboxylate transporter YP_001465636.1 4696874 R 331111 CDS YP_001465637.1 157157079 5589999 complement(4698293..4699729) 1 NC_009801.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 4699729 aspA 5589999 aspA Escherichia coli E24377A aspartate ammonia-lyase YP_001465637.1 4698293 R 331111 CDS YP_001465638.1 157155046 5590768 4700066..4700542 1 NC_009801.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4700542 fxsA 5590768 fxsA Escherichia coli E24377A FxsA protein YP_001465638.1 4700066 D 331111 CDS YP_001465639.1 157155716 5586029 complement(4700558..4701814) 1 NC_009801.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function; hypothetical protein 4701814 5586029 EcE24377A_4696 Escherichia coli E24377A hypothetical protein YP_001465639.1 4700558 R 331111 CDS YP_001465640.1 157155006 5588592 4702090..4702383 1 NC_009801.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4702383 groES 5588592 groES Escherichia coli E24377A co-chaperonin GroES YP_001465640.1 4702090 D 331111 CDS YP_001465641.1 157159099 5587547 4702427..4704073 1 NC_009801.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 4704073 groEL 5587547 groEL Escherichia coli E24377A molecular chaperone GroEL YP_001465641.1 4702427 D 331111 CDS YP_001465642.1 157157416 5586590 4704211..4704564 1 NC_009801.1 lipoprotein 4704564 5586590 EcE24377A_4699 Escherichia coli E24377A lipoprotein YP_001465642.1 4704211 D 331111 CDS YP_001465643.1 157158218 5588554 4704817..4705797 1 NC_009801.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 4705797 5588554 EcE24377A_4700 Escherichia coli E24377A IS621, transposase YP_001465643.1 4704817 D 331111 CDS YP_001465644.1 157156508 5587132 complement(4706046..4706915) 1 NC_009801.1 hypothetical protein 4706915 5587132 EcE24377A_4701 Escherichia coli E24377A hypothetical protein YP_001465644.1 4706046 R 331111 CDS YP_001465645.1 157156006 5590434 complement(4707142..4707279) 1 NC_009801.1 identified by glimmer; hypothetical protein 4707279 5590434 EcE24377A_4702 Escherichia coli E24377A hypothetical protein YP_001465645.1 4707142 R 331111 CDS YP_001465646.1 157156524 5586771 complement(4707310..4708338) 1 NC_009801.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR00238; KamA family protein 4708338 5586771 EcE24377A_4703 Escherichia coli E24377A KamA family protein YP_001465646.1 4707310 R 331111 CDS YP_001465647.1 157155474 5590233 4708380..4708946 1 NC_009801.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4708946 efp 5590233 efp Escherichia coli E24377A elongation factor P YP_001465647.1 4708380 D 331111 CDS YP_001465648.1 157157665 5588503 4708998..4709123 1 NC_009801.1 acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4709123 ecnB 5588503 ecnB Escherichia coli E24377A entericidin A YP_001465648.1 4708998 D 331111 CDS YP_001465649.1 157156900 5588809 complement(4709218..4709469) 1 NC_009801.1 identified by glimmer; hypothetical protein 4709469 5588809 EcE24377A_4706 Escherichia coli E24377A hypothetical protein YP_001465649.1 4709218 R 331111 CDS YP_001465650.1 157156036 5589123 4709555..4709872 1 NC_009801.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 4709872 sugE 5589123 sugE Escherichia coli E24377A quaternary ammonium compound-resistance protein SugE YP_001465650.1 4709555 D 331111 CDS YP_001465651.1 157155798 5589362 complement(4709869..4710402) 1 NC_009801.1 lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 4710402 blc 5589362 blc Escherichia coli E24377A outer membrane lipoprotein Blc YP_001465651.1 4709869 R 331111 CDS YP_001465652.1 157154953 5587513 complement(4710491..4711624) 1 NC_009801.1 identified by match to protein family HMM PF00144; beta-lactamase 4711624 ampC 5587513 ampC Escherichia coli E24377A beta-lactamase YP_001465652.1 4710491 R 331111 CDS YP_001465653.1 157158919 5587425 complement(4711687..4712046) 1 NC_009801.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 4712046 frdD 5587425 frdD Escherichia coli E24377A fumarate reductase subunit D YP_001465653.1 4711687 R 331111 CDS YP_001465654.1 157157388 5589906 complement(4712057..4712452) 1 NC_009801.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 4712452 frdC 5589906 frdC Escherichia coli E24377A fumarate reductase subunit C YP_001465654.1 4712057 R 331111 CDS YP_001465655.1 157156621 5589776 complement(4712463..4713197) 1 NC_009801.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 4713197 frdB 5589776 frdB Escherichia coli E24377A fumarate reductase iron-sulfur subunit YP_001465655.1 4712463 R 331111 CDS YP_001465656.1 157156850 5590072 complement(4713190..4714998) 1 NC_009801.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 4714998 frdA 5590072 frdA Escherichia coli E24377A fumarate reductase flavoprotein subunit YP_001465656.1 4713190 R 331111 CDS YP_001465657.1 157155551 5586570 4715323..4716300 1 NC_009801.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4716300 genX 5586570 genX Escherichia coli E24377A lysyl-tRNA synthetase YP_001465657.1 4715323 D 331111 CDS YP_001465658.1 157159432 5586261 4716519..4718021 1 NC_009801.1 identified by match to protein family HMM PF00324; amino acid permease 4718021 5586261 EcE24377A_4715 Escherichia coli E24377A amino acid permease YP_001465658.1 4716519 D 331111 CDS YP_001465659.1 157157848 5590366 complement(4718172..4721495) 1 NC_009801.1 identified by match to protein family HMM PF00924; hypothetical protein 4721495 5590366 EcE24377A_4716 Escherichia coli E24377A hypothetical protein YP_001465659.1 4718172 R 331111 CDS YP_001465660.1 157157207 5587521 complement(4721517..4722485) 1 NC_009801.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 4722485 psd 5587521 psd Escherichia coli E24377A phosphatidylserine decarboxylase YP_001465660.1 4721517 R 331111 CDS YP_001465661.1 157156166 5586620 complement(4722582..4723634) 1 NC_009801.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 4723634 rsgA 5586620 rsgA Escherichia coli E24377A ribosome-associated GTPase YP_001465661.1 4722582 R 331111 CDS YP_001465662.1 157155866 5589844 4723729..4724274 1 NC_009801.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4724274 orn 5589844 orn Escherichia coli E24377A oligoribonuclease YP_001465662.1 4723729 D 331111 CDS YP_001465663.1 157155174 5586457 complement(4725053..4726192) 1 NC_009801.1 identified by match to protein family HMM PF00037; match to protein family HMM PF08331; match to protein family HMM TIGR00276; iron-sulfur cluster binding protein 4726192 5586457 EcE24377A_4723 Escherichia coli E24377A iron-sulfur cluster binding protein YP_001465663.1 4725053 R 331111 CDS YP_001465664.1 157158402 5590045 4726191..4727738 1 NC_009801.1 identified by match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197; hypothetical protein 4727738 5590045 EcE24377A_4724 Escherichia coli E24377A hypothetical protein YP_001465664.1 4726191 D 331111 CDS YP_001465665.1 157158929 5588701 4727710..4728171 1 NC_009801.1 possibly involved in cell wall synthesis; ATPase 4728171 5588701 EcE24377A_4725 Escherichia coli E24377A ATPase YP_001465665.1 4727710 D 331111 CDS YP_001465666.1 157157404 5588517 4728190..4729527 1 NC_009801.1 identified by match to protein family HMM PF01520; N-acetylmuramoyl-L-alanine amidase 4729527 5588517 EcE24377A_4727 Escherichia coli E24377A N-acetylmuramoyl-L-alanine amidase YP_001465666.1 4728190 D 331111 CDS YP_001465667.1 157157412 5588931 complement(4729183..4729284) 1 NC_009801.1 identified by glimmer; hypothetical protein 4729284 5588931 EcE24377A_4726 Escherichia coli E24377A hypothetical protein YP_001465667.1 4729183 R 331111 CDS YP_001465668.1 157158119 5588560 4729537..4731384 1 NC_009801.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4731384 mutL 5588560 mutL Escherichia coli E24377A DNA mismatch repair protein YP_001465668.1 4729537 D 331111 CDS YP_001465669.1 157157755 5590276 4731377..4732327 1 NC_009801.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4732327 miaA 5590276 miaA Escherichia coli E24377A tRNA delta(2)-isopentenylpyrophosphate transferase YP_001465669.1 4731377 D 331111 CDS YP_001465670.1 157156846 5587681 4732413..4732721 1 NC_009801.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4732721 hfq 5587681 hfq Escherichia coli E24377A RNA-binding protein Hfq YP_001465670.1 4732413 D 331111 CDS YP_001465671.1 157155239 5587792 4732797..4734077 1 NC_009801.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 4734077 hflX 5587792 hflX Escherichia coli E24377A GTPase HflX YP_001465671.1 4732797 D 331111 CDS YP_001465672.1 157155151 5589911 4734163..4735422 1 NC_009801.1 with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4735422 hflK 5589911 hflK Escherichia coli E24377A FtsH protease regulator HflK YP_001465672.1 4734163 D 331111 CDS YP_001465673.1 157155878 5589899 4735425..4736429 1 NC_009801.1 with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4736429 hflC 5589899 hflC Escherichia coli E24377A FtsH protease regulator HflC YP_001465673.1 4735425 D 331111 CDS YP_001465674.1 157158982 5590163 4736511..4736708 1 NC_009801.1 hypothetical protein 4736708 5590163 EcE24377A_4735 Escherichia coli E24377A hypothetical protein YP_001465674.1 4736511 D 331111 CDS YP_001465675.1 157158298 5590408 complement(4736681..4736785) 1 NC_009801.1 identified by glimmer; hypothetical protein 4736785 5590408 EcE24377A_4734 Escherichia coli E24377A hypothetical protein YP_001465675.1 4736681 R 331111 CDS YP_001465676.1 157159156 5589695 4736812..4738110 1 NC_009801.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4738110 purA 5589695 purA Escherichia coli E24377A adenylosuccinate synthetase YP_001465676.1 4736812 D 331111 CDS YP_001465677.1 157155926 5588542 4738315..4738740 1 NC_009801.1 negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4738740 nsrR 5588542 nsrR Escherichia coli E24377A transcriptional repressor NsrR YP_001465677.1 4738315 D 331111 CDS YP_001465678.1 157156656 5589897 4738779..4741220 1 NC_009801.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4741220 rnr 5589897 rnr Escherichia coli E24377A exoribonuclease R YP_001465678.1 4738779 D 331111 CDS YP_001465679.1 157157320 5590108 4741263..4741400 1 NC_009801.1 identified by glimmer; hypothetical protein 4741400 5590108 EcE24377A_4739 Escherichia coli E24377A hypothetical protein YP_001465679.1 4741263 D 331111 CDS YP_001465680.1 157158474 5588007 4741400..4742131 1 NC_009801.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4742131 5588007 EcE24377A_4740 Escherichia coli E24377A 23S rRNA (guanosine-2'-O-)-methyltransferase YP_001465680.1 4741400 D 331111 CDS YP_001465681.1 157159138 5585920 4742258..4742659 1 NC_009801.1 identified by similarity to GB:CAD06847.1; hypothetical protein 4742659 5585920 EcE24377A_4741 Escherichia coli E24377A hypothetical protein YP_001465681.1 4742258 D 331111 CDS YP_001465682.1 157159215 5587674 4742678..4743376 1 NC_009801.1 identified by match to protein family HMM PF04012; PspA/IM30 family protein 4743376 5587674 EcE24377A_4742 Escherichia coli E24377A PspA/IM30 family protein YP_001465682.1 4742678 D 331111 CDS YP_001465683.1 157155103 5586511 4743427..4744086 1 NC_009801.1 hypothetical protein 4744086 5586511 EcE24377A_4743 Escherichia coli E24377A hypothetical protein YP_001465683.1 4743427 D 331111 CDS YP_001465684.1 157156318 5589460 4744104..4744502 1 NC_009801.1 identified by match to protein family HMM PF03994; inner membrane protein 4744502 5589460 EcE24377A_4744 Escherichia coli E24377A inner membrane protein YP_001465684.1 4744104 D 331111 CDS YP_001465685.1 157157096 5586908 4744512..4745150 1 NC_009801.1 identified by match to protein family HMM PF06693; hypothetical protein 4745150 5586908 EcE24377A_4745 Escherichia coli E24377A hypothetical protein YP_001465685.1 4744512 D 331111 CDS YP_001465686.1 157157157 5586286 4745153..4746316 1 NC_009801.1 identified by match to protein family HMM PF03738; glutathionylspermidine synthase 4746316 5586286 EcE24377A_4746 Escherichia coli E24377A glutathionylspermidine synthase YP_001465686.1 4745153 D 331111 CDS YP_001465687.1 157158060 5590511 4746400..4748025 1 NC_009801.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4748025 5590511 EcE24377A_4747 Escherichia coli E24377A isovaleryl CoA dehydrogenase YP_001465687.1 4746400 D 331111 CDS YP_001465688.1 157157410 5586177 complement(4748142..4748429) 1 NC_009801.1 identified by match to protein family HMM PF07338; hypothetical protein 4748429 5586177 EcE24377A_4748 Escherichia coli E24377A hypothetical protein YP_001465688.1 4748142 R 331111 CDS YP_001465689.1 157158116 5588904 complement(4748566..4748994) 1 NC_009801.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A 4748994 5588904 EcE24377A_4749 Escherichia coli E24377A biofilm stress and motility protein A YP_001465689.1 4748566 R 331111 CDS YP_001465690.1 157156077 5587089 4749077..4749826 1 NC_009801.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4749826 5587089 EcE24377A_4751 Escherichia coli E24377A esterase YP_001465690.1 4749077 D 331111 CDS YP_001465691.1 157156767 5590711 complement(4749823..4750578) 1 NC_009801.1 negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 4750578 ulaR 5590711 ulaR Escherichia coli E24377A transcriptional repressor UlaR YP_001465691.1 4749823 R 331111 CDS YP_001465692.1 157155418 5589543 complement(4750686..4751750) 1 NC_009801.1 identified by similarity to SP:P39300; L-ascorbate 6-phosphate lactonase 4751750 5589543 EcE24377A_4752 Escherichia coli E24377A L-ascorbate 6-phosphate lactonase YP_001465692.1 4750686 R 331111 CDS YP_001465693.1 157156141 5587074 4752105..4753502 1 NC_009801.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4753502 ulaA 5587074 ulaA Escherichia coli E24377A PTS system ascorbate-specific transporter subunit IIC YP_001465693.1 4752105 D 331111 CDS YP_001465694.1 157154754 5589231 4753833..4754297 1 NC_009801.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 4754297 ulaC 5589231 ulaC Escherichia coli E24377A PTS system L-ascorbate-specific transporter subunit IIA YP_001465694.1 4753833 D 331111 CDS YP_001465695.1 157156034 5590470 4754311..4754961 1 NC_009801.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4754961 ulaD 5590470 ulaD Escherichia coli E24377A 3-keto-L-gulonate-6-phosphate decarboxylase YP_001465695.1 4754311 D 331111 CDS YP_001465696.1 157158123 5585963 complement(4754317..4754985) 1 NC_009801.1 identified by glimmer; hypothetical protein 4754985 5585963 EcE24377A_4756 Escherichia coli E24377A hypothetical protein YP_001465696.1 4754317 R 331111 CDS YP_001465697.1 157155743 5590854 4754971..4755825 1 NC_009801.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4755825 ulaE 5590854 ulaE Escherichia coli E24377A L-xylulose 5-phosphate 3-epimerase YP_001465697.1 4754971 D 331111 CDS YP_001465698.1 157155018 5590579 4755825..4756511 1 NC_009801.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4756511 sgaE 5590579 sgaE Escherichia coli E24377A L-ribulose-5-phosphate 4-epimerase YP_001465698.1 4755825 D 331111 CDS YP_001465699.1 157157095 5587917 complement(4756640..4756915) 1 NC_009801.1 identified by match to protein family HMM PF07338; hypothetical protein 4756915 5587917 EcE24377A_4760 Escherichia coli E24377A hypothetical protein YP_001465699.1 4756640 R 331111 CDS YP_001465700.1 157157810 5586285 4757242..4757637 1 NC_009801.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4757637 rpsF 5586285 rpsF Escherichia coli E24377A 30S ribosomal protein S6 YP_001465700.1 4757242 D 331111 CDS YP_001465701.1 157157219 5587699 4757644..4757958 1 NC_009801.1 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4757958 priB 5587699 priB Escherichia coli E24377A primosomal replication protein N YP_001465701.1 4757644 D 331111 CDS YP_001465702.1 157158640 5590186 4757963..4758190 1 NC_009801.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4758190 rpsR 5590186 rpsR Escherichia coli E24377A 30S ribosomal protein S18 YP_001465702.1 4757963 D 331111 CDS YP_001465703.1 157155245 5585899 4758232..4758681 1 NC_009801.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4758681 rplI 5585899 rplI Escherichia coli E24377A 50S ribosomal protein L9 YP_001465703.1 4758232 D 331111 CDS YP_001465704.1 157158149 5586156 complement(4758793..4759764) 1 NC_009801.1 identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787; TRAP transporter solute receptor DctP family protein 4759764 5586156 EcE24377A_4765 Escherichia coli E24377A TRAP transporter solute receptor DctP family protein YP_001465704.1 4758793 R 331111 CDS YP_001465705.1 157159334 5587508 complement(4759817..4761118) 1 NC_009801.1 identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786; TRAP C4-dicarboxylate transport system permease DctM 4761118 5587508 EcE24377A_4766 Escherichia coli E24377A TRAP C4-dicarboxylate transport system permease DctM YP_001465705.1 4759817 R 331111 CDS YP_001465706.1 157158491 5589472 complement(4761658..4763739) 1 NC_009801.1 identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF07992; pyridine nucleotide-disulfide oxidoreductase 4763739 5589472 EcE24377A_4767 Escherichia coli E24377A pyridine nucleotide-disulfide oxidoreductase YP_001465706.1 4761658 R 331111 CDS YP_001465707.1 157155448 5588004 complement(4763736..4765277) 1 NC_009801.1 identified by match to protein family HMM PF01144; CoA-transferase 4765277 5588004 EcE24377A_4768 Escherichia coli E24377A CoA-transferase YP_001465707.1 4763736 R 331111 CDS YP_001465708.1 157155155 5588219 4765239..4765367 1 NC_009801.1 identified by glimmer; hypothetical protein 4765367 5588219 EcE24377A_4770 Escherichia coli E24377A hypothetical protein YP_001465708.1 4765239 D 331111 CDS YP_001465709.1 157155836 5590749 complement(4765287..4766063) 1 NC_009801.1 identified by match to protein family HMM PF00378; enoyl-CoA hydratase 4766063 5590749 EcE24377A_4769 Escherichia coli E24377A enoyl-CoA hydratase YP_001465709.1 4765287 R 331111 CDS YP_001465710.1 157156968 5586858 complement(4766073..4766915) 1 NC_009801.1 identified by match to protein family HMM PF01261; AP endonuclease 4766915 5586858 EcE24377A_4771 Escherichia coli E24377A AP endonuclease YP_001465710.1 4766073 R 331111 CDS YP_001465711.1 157156300 5590084 complement(4766925..4767716) 1 NC_009801.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 4767716 5590084 EcE24377A_4772 Escherichia coli E24377A 3-ketoacyl-ACP reductase YP_001465711.1 4766925 R 331111 CDS YP_001465712.1 157157458 5588774 4767926..4768564 1 NC_009801.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4768564 5588774 EcE24377A_4773 Escherichia coli E24377A TetR family transcriptional regulator YP_001465712.1 4767926 D 331111 CDS YP_001465713.1 157155588 5586951 4769413..4770033 1 NC_009801.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4770033 fklB 5586951 fklB Escherichia coli E24377A peptidyl-prolyl cis-trans isomerase YP_001465713.1 4769413 D 331111 CDS YP_001465714.1 157158682 5589782 4770342..4771754 1 NC_009801.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4771754 cycA 5589782 cycA Escherichia coli E24377A D-alanine/D-serine/glycine permease YP_001465714.1 4770342 D 331111 CDS YP_001465715.1 157157614 5586721 4771772..4772440 1 NC_009801.1 identified by glimmer; hypothetical protein 4772440 5586721 EcE24377A_4778 Escherichia coli E24377A hypothetical protein YP_001465715.1 4771772 D 331111 CDS YP_001465716.1 157159348 5590670 complement(4771799..4772461) 1 NC_009801.1 Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein 4772461 5590670 EcE24377A_4777 Escherichia coli E24377A iron-sulfur cluster repair di-iron protein YP_001465716.1 4771799 R 331111 CDS YP_001465717.1 157157606 5587867 complement(4772569..4773534) 1 NC_009801.1 identified by similarity to SP:P39314; match to protein family HMM PF00892; hypothetical protein 4773534 5587867 EcE24377A_4779 Escherichia coli E24377A hypothetical protein YP_001465717.1 4772569 R 331111 CDS YP_001465718.1 157158268 5588833 4773547..4773645 1 NC_009801.1 identified by glimmer; hypothetical protein 4773645 5588833 EcE24377A_4781 Escherichia coli E24377A hypothetical protein YP_001465718.1 4773547 D 331111 CDS YP_001465719.1 157156586 5586817 complement(4773642..4774502) 1 NC_009801.1 identified by match to protein family HMM PF01073; match to protein family HMM PF05368; NmrA family protein 4774502 5586817 EcE24377A_4780 Escherichia coli E24377A NmrA family protein YP_001465719.1 4773642 R 331111 CDS YP_001465720.1 157154925 5587955 4774591..4774971 1 NC_009801.1 identified by match to protein family HMM PF01638; transcriptional regulator 4774971 5587955 EcE24377A_4782 Escherichia coli E24377A transcriptional regulator YP_001465720.1 4774591 D 331111 CDS YP_001465721.1 157154929 5586786 complement(4775100..4777043) 1 NC_009801.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 4777043 cpdB 5586786 cpdB Escherichia coli E24377A bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein YP_001465721.1 4775100 R 331111 CDS YP_001465722.1 157156842 5589349 4777233..4777973 1 NC_009801.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4777973 cysQ 5589349 cysQ Escherichia coli E24377A adenosine-3'(2'),5'-bisphosphate nucleotidase YP_001465722.1 4777233 D 331111 CDS YP_001465723.1 157156313 5589360 complement(4777963..4778520) 1 NC_009801.1 identified by match to protein family HMM TIGR01626; hypothetical protein 4778520 5589360 EcE24377A_4784 Escherichia coli E24377A hypothetical protein YP_001465723.1 4777963 R 331111 CDS YP_001465724.1 157156376 5587498 4778845..4779051 1 NC_009801.1 identified by match to protein family HMM PF06526; hypothetical protein 4779051 5587498 EcE24377A_4786 Escherichia coli E24377A hypothetical protein YP_001465724.1 4778845 D 331111 CDS YP_001465725.1 157157274 5589428 complement(4779130..4780473) 1 NC_009801.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; transporter 4780473 5589428 EcE24377A_4787 Escherichia coli E24377A transporter YP_001465725.1 4779130 R 331111 CDS YP_001465726.1 157159117 5589834 complement(4780626..4780763) 1 NC_009801.1 identified by glimmer; hypothetical protein 4780763 5589834 EcE24377A_4788 Escherichia coli E24377A hypothetical protein YP_001465726.1 4780626 R 331111 CDS YP_001465727.1 157158331 5587422 complement(4780796..4781434) 1 NC_009801.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 4781434 msrA 5587422 msrA Escherichia coli E24377A methionine sulfoxide reductase A YP_001465727.1 4780796 R 331111 CDS YP_001465728.1 157155444 5589783 4781640..4783373 1 NC_009801.1 identified by match to protein family HMM PF01103; match to protein family HMM PF07244; OMP85 family outer membrane protein 4783373 5589783 EcE24377A_4790 Escherichia coli E24377A OMP85 family outer membrane protein YP_001465728.1 4781640 D 331111 CDS YP_001465729.1 157155179 5589886 4783370..4787149 1 NC_009801.1 identified by match to protein family HMM PF04357; hypothetical protein 4787149 5589886 EcE24377A_4791 Escherichia coli E24377A hypothetical protein YP_001465729.1 4783370 D 331111 CDS YP_001465730.1 157157064 5588768 4787152..4787493 1 NC_009801.1 identified by match to protein family HMM PF03674; hypothetical protein 4787493 5588768 EcE24377A_4792 Escherichia coli E24377A hypothetical protein YP_001465730.1 4787152 D 331111 CDS YP_001465731.1 157156816 5585980 4787705..4787956 1 NC_009801.1 part of the toxin-antitoxin ChpB-ChpS system; antitoxin ChpS 4787956 chpS 5585980 chpS Escherichia coli E24377A antitoxin ChpS YP_001465731.1 4787705 D 331111 CDS YP_001465732.1 157157445 5586800 4787950..4788300 1 NC_009801.1 toxin of the ChpB-ChpS toxin-antitoxin system; toxin ChpB 4788300 chpB 5586800 chpB Escherichia coli E24377A toxin ChpB YP_001465732.1 4787950 D 331111 CDS YP_001465733.1 157157788 5586730 complement(4788380..4788910) 1 NC_009801.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 4788910 ppa 5586730 ppa Escherichia coli E24377A inorganic pyrophosphatase YP_001465733.1 4788380 R 331111 CDS YP_001465734.1 157157137 5589015 complement(4788922..4789047) 1 NC_009801.1 identified by similarity to GB:AAN83745.1; hypothetical protein 4789047 5589015 EcE24377A_4796 Escherichia coli E24377A hypothetical protein YP_001465734.1 4788922 R 331111 CDS YP_001465735.1 157159174 5589920 4789220..4790176 1 NC_009801.1 identified by match to protein family HMM PF00532; sugar ABC transporter periplasmic sugar-binding protein 4790176 5589920 EcE24377A_4797 Escherichia coli E24377A sugar ABC transporter periplasmic sugar-binding protein YP_001465735.1 4789220 D 331111 CDS YP_001465736.1 157158508 5587970 4790316..4791818 1 NC_009801.1 identified by match to protein family HMM PF00005; sugar ABC transporter ATP-binding protein 4791818 5587970 EcE24377A_4798 Escherichia coli E24377A sugar ABC transporter ATP-binding protein YP_001465736.1 4790316 D 331111 CDS YP_001465737.1 157155033 5590107 4791829..4792854 1 NC_009801.1 identified by match to protein family HMM PF02653; sugar ABC transporter permease 4792854 5590107 EcE24377A_4799 Escherichia coli E24377A sugar ABC transporter permease YP_001465737.1 4791829 D 331111 CDS YP_001465738.1 157156783 5589488 4792841..4793836 1 NC_009801.1 membrane component of a sugar ABC transporter system; ABC transporter permease 4793836 5589488 EcE24377A_4800 Escherichia coli E24377A ABC transporter permease YP_001465738.1 4792841 D 331111 CDS YP_001465739.1 157156501 5587064 complement(4793869..4794867) 1 NC_009801.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 4794867 fbp 5587064 fbp Escherichia coli E24377A fructose-1,6-bisphosphatase YP_001465739.1 4793869 R 331111 CDS YP_001465740.1 157158144 5588341 4794930..4795061 1 NC_009801.1 hypothetical protein 4795061 5588341 EcE24377A_4802 Escherichia coli E24377A hypothetical protein YP_001465740.1 4794930 D 331111 CDS YP_001465741.1 157156216 5589301 4795043..4796416 1 NC_009801.1 identified by similarity to SP:P37773; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01081; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4796416 mpl 5589301 mpl Escherichia coli E24377A UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_001465741.1 4795043 D 331111 CDS YP_001465742.1 157154908 5590264 complement(4796567..4797118) 1 NC_009801.1 identified by match to protein family HMM PF04751; hypothetical protein 4797118 yjgA 5590264 yjgA Escherichia coli E24377A hypothetical protein YP_001465742.1 4796567 R 331111 CDS YP_001465743.1 157159292 5587661 4797224..4798564 1 NC_009801.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4798564 pmbA 5587661 pmbA Escherichia coli E24377A peptidase PmbA YP_001465743.1 4797224 D 331111 CDS YP_001465744.1 157158617 5588827 4798747..4799133 1 NC_009801.1 identified by similarity to SP:P0ABE7; match to protein family HMM PF07361; soluble cytochrome b562 4799133 cybC 5588827 cybC Escherichia coli E24377A soluble cytochrome b562 YP_001465744.1 4798747 D 331111 CDS YP_001465745.1 157158234 5589452 complement(4799178..4799642) 1 NC_009801.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 4799642 nrdG 5589452 nrdG Escherichia coli E24377A anaerobic ribonucleotide reductase-activating protein YP_001465745.1 4799178 R 331111 CDS YP_001465746.1 157157795 5587212 complement(4799639..4799743) 1 NC_009801.1 identified by glimmer; hypothetical protein 4799743 5587212 EcE24377A_4808 Escherichia coli E24377A hypothetical protein YP_001465746.1 4799639 R 331111 CDS YP_001465747.1 157157950 5587673 complement(4799801..4801939) 1 NC_009801.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 4801939 nrdD 5587673 nrdD Escherichia coli E24377A anaerobic ribonucleoside triphosphate reductase YP_001465747.1 4799801 R 331111 CDS YP_001465748.1 157156855 5588450 4802144..4802260 1 NC_009801.1 identified by similarity to GB:CAD06913.1; hypothetical protein 4802260 5588450 EcE24377A_4810 Escherichia coli E24377A hypothetical protein YP_001465748.1 4802144 D 331111 CDS YP_001465749.1 157155240 5588565 complement(4802333..4803988) 1 NC_009801.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403; trehalose-6-phosphate hydrolase 4803988 treC 5588565 treC Escherichia coli E24377A trehalose-6-phosphate hydrolase YP_001465749.1 4802333 R 331111 CDS YP_001465750.1 157155820 5587399 complement(4804038..4805456) 1 NC_009801.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunit IIBC 4805456 treB 5587399 treB Escherichia coli E24377A PTS system trehalose(maltose)-specific transporter subunit IIBC YP_001465750.1 4804038 R 331111 CDS YP_001465751.1 157158377 5586116 complement(4805578..4806525) 1 NC_009801.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 4806525 treR 5586116 treR Escherichia coli E24377A trehalose repressor YP_001465751.1 4805578 R 331111 CDS YP_001465752.1 157159071 5587608 4806904..4809600 1 NC_009801.1 P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4809600 mgtA 5587608 mgtA Escherichia coli E24377A magnesium-transporting ATPase MgtA YP_001465752.1 4806904 D 331111 CDS YP_001465753.1 157158526 5588423 complement(4809828..4810808) 1 NC_009801.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371; IS621, transposase 4810808 5588423 EcE24377A_4815 Escherichia coli E24377A IS621, transposase YP_001465753.1 4809828 R 331111 CDS YP_001465754.1 157157702 5587506 complement(4811085..4811471) 1 NC_009801.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; endoribonuclease L-PSP 4811471 5587506 EcE24377A_4816 Escherichia coli E24377A endoribonuclease L-PSP YP_001465754.1 4811085 R 331111 CDS YP_001465755.1 157157204 5586213 complement(4811544..4812005) 1 NC_009801.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase 4812005 pyrI 5586213 pyrI Escherichia coli E24377A aspartate carbamoyltransferase YP_001465755.1 4811544 R 331111 CDS YP_001465756.1 157157005 5590325 complement(4812018..4812953) 1 NC_009801.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 4812953 pyrB 5590325 pyrB Escherichia coli E24377A aspartate carbamoyltransferase YP_001465756.1 4812018 R 331111 CDS YP_001465757.1 157158463 5586322 complement(4813195..4813299) 1 NC_009801.1 identified by glimmer; hypothetical protein 4813299 5586322 EcE24377A_4819 Escherichia coli E24377A hypothetical protein YP_001465757.1 4813195 R 331111 CDS YP_001465758.1 157157785 5586572 complement(4813372..4813767) 1 NC_009801.1 identified by match to protein family HMM PF01042; endoribonuclease L-PSP 4813767 5586572 EcE24377A_4820 Escherichia coli E24377A endoribonuclease L-PSP YP_001465758.1 4813372 R 331111 CDS YP_001465759.1 157157825 5590476 complement(4813898..4814611) 1 NC_009801.1 identified by match to protein family HMM PF00106; oxidoreductase 4814611 5590476 EcE24377A_4821 Escherichia coli E24377A oxidoreductase YP_001465759.1 4813898 R 331111 CDS YP_001465760.1 157157297 5589077 4814682..4815275 1 NC_009801.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 4815275 5589077 EcE24377A_4822 Escherichia coli E24377A TetR family transcriptional regulator YP_001465760.1 4814682 D 331111 CDS YP_001465761.1 157155241 5588975 4815420..4815872 1 NC_009801.1 identified by similarity to SP:P0AF97; match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 4815872 5588975 EcE24377A_4823 Escherichia coli E24377A hypothetical protein YP_001465761.1 4815420 D 331111 CDS YP_001465762.1 157155943 5586475 complement(4817651..4818664) 1 NC_009801.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I 4818664 argF 5586475 argF Escherichia coli E24377A ornithine carbamoyltransferase subunit I YP_001465762.1 4817651 R 331111 CDS YP_001465763.1 157155422 5587277 4818826..4819242 1 NC_009801.1 identified by similarity to PDB:1NXI_A; match to protein family HMM PF06877; hypothetical protein 4819242 5587277 EcE24377A_4826 Escherichia coli E24377A hypothetical protein YP_001465763.1 4818826 D 331111 CDS YP_001465764.1 157154907 5590465 complement(4819288..4819791) 1 NC_009801.1 identified by match to protein family HMM PF00583; acetyltransferase 4819791 5590465 EcE24377A_4827 Escherichia coli E24377A acetyltransferase YP_001465764.1 4819288 R 331111 CDS YP_001465765.1 157159142 5587660 4819984..4821180 1 NC_009801.1 identified by match to protein family HMM PF05987; hypothetical protein 4821180 5587660 EcE24377A_4828 Escherichia coli E24377A hypothetical protein YP_001465765.1 4819984 D 331111 CDS YP_001465766.1 157158681 5589285 complement(4821236..4824091) 1 NC_009801.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 4824091 valS 5589285 valS Escherichia coli E24377A valyl-tRNA synthetase YP_001465766.1 4821236 R 331111 CDS YP_001465767.1 157159204 5586540 complement(4824091..4824534) 1 NC_009801.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 4824534 holC 5586540 holC Escherichia coli E24377A DNA polymerase III subunit chi YP_001465767.1 4824091 R 331111 CDS YP_001465768.1 157155610 5589188 complement(4824619..4824852) 1 NC_009801.1 identified by glimmer; hypothetical protein 4824852 5589188 EcE24377A_4831 Escherichia coli E24377A hypothetical protein YP_001465768.1 4824619 R 331111 CDS YP_001465769.1 157158199 5587041 complement(4824888..4826399) 1 NC_009801.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 4826399 pepA 5587041 pepA Escherichia coli E24377A leucyl aminopeptidase YP_001465769.1 4824888 R 331111 CDS YP_001465770.1 157157059 5587340 4826666..4827766 1 NC_009801.1 identified by match to protein family HMM PF03739; putaitve permease 4827766 5587340 EcE24377A_4834 Escherichia coli E24377A putaitve permease YP_001465770.1 4826666 D 331111 CDS YP_001465771.1 157155171 5589447 4827766..4828848 1 NC_009801.1 identified by match to protein family HMM PF03739; permease 4828848 5589447 EcE24377A_4835 Escherichia coli E24377A permease YP_001465771.1 4827766 D 331111 CDS YP_001465772.1 157158413 5587732 complement(4829009..4830511) 1 NC_009801.1 identified by match to protein family HMM PF05872; hypothetical protein 4830511 5587732 EcE24377A_4836 Escherichia coli E24377A hypothetical protein YP_001465772.1 4829009 R 331111 CDS YP_001465773.1 157158628 5586102 complement(4830639..4831658) 1 NC_009801.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; zinc-binding dehydrogenase oxidoreductase 4831658 5586102 EcE24377A_4837 Escherichia coli E24377A zinc-binding dehydrogenase oxidoreductase YP_001465773.1 4830639 R 331111 CDS YP_001465774.1 157157112 5589833 4832137..4832439 1 NC_009801.1 identified by glimmer; hypothetical protein 4832439 5589833 EcE24377A_4839 Escherichia coli E24377A hypothetical protein YP_001465774.1 4832137 D 331111 CDS YP_001465775.1 157157242 5587569 complement(4833844..4835352) 1 NC_009801.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388; group II intron-encoded reverse transcriptase/maturase 4835352 5587569 EcE24377A_4841 Escherichia coli E24377A group II intron-encoded reverse transcriptase/maturase YP_001465775.1 4833844 R 331111 CDS YP_001465776.1 157155073 5588352 complement(4836438..4836764) 1 NC_009801.1 identified by match to protein family HMM PF01527; IS629, transposase orfA 4836764 5588352 EcE24377A_4843 Escherichia coli E24377A IS629, transposase orfA YP_001465776.1 4836438 R 331111 CDS YP_001465777.1 157155000 5587890 4836939..4837232 1 NC_009801.1 identified by match to protein family HMM PF01695; IS100, transposition helper protein, truncation 4837232 5587890 EcE24377A_4844 Escherichia coli E24377A IS100, transposition helper protein, truncation YP_001465777.1 4836939 D 331111 CDS YP_001465778.1 157158781 5586402 complement(4837283..4837501) 1 NC_009801.1 identified by match to protein family HMM PF00440; match to protein family HMM PF02178; TetR family transcriptional regulator 4837501 5586402 EcE24377A_4845 Escherichia coli E24377A TetR family transcriptional regulator YP_001465778.1 4837283 R 331111 CDS YP_001465779.1 157155701 5587206 4837568..4837867 1 NC_009801.1 identified by match to protein family HMM PF01527; IS3, transposase orfA 4837867 5587206 EcE24377A_4846 Escherichia coli E24377A IS3, transposase orfA YP_001465779.1 4837568 D 331111 CDS YP_001465780.1 157157216 5587657 4837864..4838730 1 NC_009801.1 identified by similarity to SP:P05822; match to protein family HMM PF00665; IS3, transposase orfB 4838730 5587657 EcE24377A_4847 Escherichia coli E24377A IS3, transposase orfB YP_001465780.1 4837864 D 331111 CDS YP_001465781.1 157159431 5586273 complement(4838828..4838989) 1 NC_009801.1 identified by glimmer; hypothetical protein 4838989 5586273 EcE24377A_4848 Escherichia coli E24377A hypothetical protein YP_001465781.1 4838828 R 331111 CDS YP_001465782.1 157156131 5590365 complement(4839010..4840287) 1 NC_009801.1 identified by similarity to GB:AAN68935.1; hypothetical protein 4840287 5590365 EcE24377A_4849 Escherichia coli E24377A hypothetical protein YP_001465782.1 4839010 R 331111 CDS YP_001465783.1 157157763 5586870 complement(4840350..4842353) 1 NC_009801.1 identified by match to protein family HMM PF02028; match to protein family HMM TIGR00842; BCCT family transporter 4842353 5586870 EcE24377A_4850 Escherichia coli E24377A BCCT family transporter YP_001465783.1 4840350 R 331111 CDS YP_001465784.1 157156882 5589272 complement(4842501..4843640) 1 NC_009801.1 Note that the 2 orfs of the ISSd1 transposase appear to be fused in this version of the element.; identified by match to protein family HMM PF00665; match to protein family HMM PF01527; ISSd1, transposase orfA/B, fusion 4843640 5589272 EcE24377A_4851 Escherichia coli E24377A ISSd1, transposase orfA/B, fusion YP_001465784.1 4842501 R 331111 CDS YP_001465785.1 157157717 5586834 complement(4843821..4844765) 1 NC_009801.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 4844765 msbB2 5586834 msbB2 Escherichia coli E24377A lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_001465785.1 4843821 R 331111 CDS YP_001465786.1 157155751 5588006 complement(4844830..4845780) 1 NC_009801.1 identified by match to protein family HMM PF04393; hypothetical protein 4845780 5588006 EcE24377A_4853 Escherichia coli E24377A hypothetical protein YP_001465786.1 4844830 R 331111 CDS YP_001465787.1 157155163 5589237 complement(4845785..4846873) 1 NC_009801.1 identified by match to protein family HMM PF00534; glycoside hydrolase family protein 4846873 5589237 EcE24377A_4854 Escherichia coli E24377A glycoside hydrolase family protein YP_001465787.1 4845785 R 331111 CDS YP_001465788.1 157158531 5587078 complement(4846876..4847697) 1 NC_009801.1 identified by match to protein family HMM PF01522; polysaccharide deacetylase 4847697 5587078 EcE24377A_4855 Escherichia coli E24377A polysaccharide deacetylase YP_001465788.1 4846876 R 331111 CDS YP_001465789.1 157155674 5590417 4847904..4848206 1 NC_009801.1 identified by match to protein family HMM PF01527; IS911, transposase orfA 4848206 5590417 EcE24377A_4856 Escherichia coli E24377A IS911, transposase orfA YP_001465789.1 4847904 D 331111 CDS YP_001465790.1 157159042 5590055 4849294..4850802 1 NC_009801.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388; group II intron-encoded reverse transcriptase/maturase 4850802 5590055 EcE24377A_4858 Escherichia coli E24377A group II intron-encoded reverse transcriptase/maturase YP_001465790.1 4849294 D 331111 CDS YP_001465791.1 157157190 5590629 complement(4851405..4852943) 1 NC_009801.1 identified by match to protein family HMM PF03050; IS66 family transposase 4852943 5590629 EcE24377A_4860 Escherichia coli E24377A IS66 family transposase YP_001465791.1 4851405 R 331111 CDS YP_001465792.1 157155123 5587323 complement(4852993..4853340) 1 NC_009801.1 identified by match to protein family HMM PF05717; IS66 family orf2 4853340 5587323 EcE24377A_4861 Escherichia coli E24377A IS66 family orf2 YP_001465792.1 4852993 R 331111 CDS YP_001465793.1 157154759 5587060 complement(4853337..4853726) 1 NC_009801.1 identified by match to protein family HMM PF01527; IS66 family orf1 4853726 5587060 EcE24377A_4862 Escherichia coli E24377A IS66 family orf1 YP_001465793.1 4853337 R 331111 CDS YP_001465794.1 157155404 5587662 4853903..4854160 1 NC_009801.1 identified by similarity to GB:CAG75835.1; hypothetical protein 4854160 5587662 EcE24377A_4863 Escherichia coli E24377A hypothetical protein YP_001465794.1 4853903 D 331111 CDS YP_001465795.1 157156105 5587357 complement(4854718..4855485) 1 NC_009801.1 Part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter ATP-binding subunit 4855485 fecE 5587357 fecE Escherichia coli E24377A iron-dicitrate transporter ATP-binding subunit YP_001465795.1 4854718 R 331111 CDS YP_001465796.1 157158493 5586536 complement(4855486..4856442) 1 NC_009801.1 Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter.; iron-dicitrate transporter subunit FecD 4856442 fecD 5586536 fecD Escherichia coli E24377A iron-dicitrate transporter subunit FecD YP_001465796.1 4855486 R 331111 CDS YP_001465797.1 157159183 5587369 complement(4856439..4857437) 1 NC_009801.1 part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter permease subunit 4857437 fecC 5587369 fecC Escherichia coli E24377A iron-dicitrate transporter permease subunit YP_001465797.1 4856439 R 331111 CDS YP_001465798.1 157155064 5587762 complement(4857434..4858342) 1 NC_009801.1 part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+); iron-dicitrate transporter substrate-binding subunit 4858342 fecB 5587762 fecB Escherichia coli E24377A iron-dicitrate transporter substrate-binding subunit YP_001465798.1 4857434 R 331111 CDS YP_001465799.1 157155746 5586888 complement(4858381..4860705) 1 NC_009801.1 identified by similarity to SP:P13036; match to protein family HMM PF00593; match to protein family HMM PF07660; match to protein family HMM PF07715; match to protein family HMM TIGR01783; iron(III) dicitrate transport protein FecA 4860705 fecA 5586888 fecA Escherichia coli E24377A iron(III) dicitrate transport protein FecA YP_001465799.1 4858381 R 331111 CDS YP_001465800.1 157156411 5586956 complement(4860792..4861745) 1 NC_009801.1 with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon; fec operon regulator FecR 4861745 fecR 5586956 fecR Escherichia coli E24377A fec operon regulator FecR YP_001465800.1 4860792 R 331111 CDS YP_001465801.1 157155973 5590850 complement(4861742..4862263) 1 NC_009801.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport; RNA polymerase sigma factor FecI 4862263 fecI 5590850 fecI Escherichia coli E24377A RNA polymerase sigma factor FecI YP_001465801.1 4861742 R 331111 CDS YP_001465802.1 157156339 5589753 4862555..4862830 1 NC_009801.1 identified by match to protein family HMM PF03811; IS1, transposase orfA 4862830 5589753 EcE24377A_4871 Escherichia coli E24377A IS1, transposase orfA YP_001465802.1 4862555 D 331111 CDS YP_001465803.1 157158371 5590510 complement(4863780..4863890) 1 NC_009801.1 identified by glimmer; hypothetical protein 4863890 5590510 EcE24377A_4873 Escherichia coli E24377A hypothetical protein YP_001465803.1 4863780 R 331111 CDS YP_001465804.1 157158887 5587693 complement(4864609..4864719) 1 NC_009801.1 IS629, transposase orfB, truncation 4864719 5587693 EcE24377A_4874 Escherichia coli E24377A IS629, transposase orfB, truncation YP_001465804.1 4864609 R 331111 CDS YP_001465805.1 157155238 5586846 4864881..4864991 1 NC_009801.1 identified by glimmer; hypothetical protein 4864991 5586846 EcE24377A_4875 Escherichia coli E24377A hypothetical protein YP_001465805.1 4864881 D 331111 CDS YP_001465806.1 157155761 5590135 4865007..4866380 1 NC_009801.1 identified by glimmer; hypothetical protein 4866380 5590135 EcE24377A_4876 Escherichia coli E24377A hypothetical protein YP_001465806.1 4865007 D 331111 CDS YP_001465807.1 157155980 5587265 complement(4868053..4868400) 1 NC_009801.1 identified by match to protein family HMM PF05717; IS66 family orf2 4868400 5587265 EcE24377A_4878 Escherichia coli E24377A IS66 family orf2 YP_001465807.1 4868053 R 331111 CDS YP_001465808.1 157154817 5588637 complement(4868452..4870023) 1 NC_009801.1 identified by match to protein family HMM PF03050; IS66 family transposase 4870023 5588637 EcE24377A_4879 Escherichia coli E24377A IS66 family transposase YP_001465808.1 4868452 R 331111 CDS YP_001465809.1 157159040 5587172 complement(4870043..4870390) 1 NC_009801.1 identified by match to protein family HMM PF05717; IS66 family orf2 4870390 5587172 EcE24377A_4880 Escherichia coli E24377A IS66 family orf2 YP_001465809.1 4870043 R 331111 CDS YP_001465810.1 157159377 5589690 complement(4870390..4871067) 1 NC_009801.1 identified by match to protein family HMM PF01527; IS66 family orf1 4871067 5589690 EcE24377A_4881 Escherichia coli E24377A IS66 family orf1 YP_001465810.1 4870390 R 331111 CDS YP_001465811.1 157157437 5587453 complement(4871839..4872273) 1 NC_009801.1 identified by similarity to GB:ABB64202.1; hypothetical protein 4872273 5587453 EcE24377A_4883 Escherichia coli E24377A hypothetical protein YP_001465811.1 4871839 R 331111 CDS YP_001465812.1 157156099 5590218 4872628..4873497 1 NC_009801.1 identified by glimmer; hypothetical protein 4873497 5590218 EcE24377A_4885 Escherichia coli E24377A hypothetical protein YP_001465812.1 4872628 D 331111 CDS YP_001465813.1 157156934 5588705 complement(4872922..4873491) 1 NC_009801.1 hypothetical protein 4873491 5588705 EcE24377A_4884 Escherichia coli E24377A hypothetical protein YP_001465813.1 4872922 R 331111 CDS YP_001465814.1 157155657 5587817 complement(4874236..4874412) 1 NC_009801.1 identified by match to protein family HMM PF05321; hemolysin expression modulating protein 4874412 5587817 EcE24377A_4886 Escherichia coli E24377A hemolysin expression modulating protein YP_001465814.1 4874236 R 331111 CDS YP_001465815.1 157159190 5588278 4875047..4875325 1 NC_009801.1 identified by match to protein family HMM PF05930; prophage CP4-57 regulatory protein AlpA 4875325 5588278 EcE24377A_4887 Escherichia coli E24377A prophage CP4-57 regulatory protein AlpA YP_001465815.1 4875047 D 331111 CDS YP_001465816.1 157157337 5588118 4875414..4876022 1 NC_009801.1 identified by similarity to GB:AAL08467.1; hypothetical protein 4876022 5588118 EcE24377A_4888 Escherichia coli E24377A hypothetical protein YP_001465816.1 4875414 D 331111 CDS YP_001465817.1 157155631 5587168 complement(4876346..4876438) 1 NC_009801.1 identified by glimmer; hypothetical protein 4876438 5587168 EcE24377A_4889 Escherichia coli E24377A hypothetical protein YP_001465817.1 4876346 R 331111 CDS YP_001465818.1 157155101 5588092 4877208..4878125 1 NC_009801.1 identified by similarity to GB:AAL08470.1; hypothetical protein 4878125 5588092 EcE24377A_4890 Escherichia coli E24377A hypothetical protein YP_001465818.1 4877208 D 331111 CDS YP_001465819.1 157154877 5588235 4878210..4879082 1 NC_009801.1 identified by match to protein family HMM PF01926; GTPase 4879082 5588235 EcE24377A_4891 Escherichia coli E24377A GTPase YP_001465819.1 4878210 D 331111 CDS YP_001465820.1 157158925 5587671 4879454..4882300 1 NC_009801.1 identified by similarity to SP:P39180; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; antigen 43 4882300 flu1 5587671 flu1 Escherichia coli E24377A antigen 43 YP_001465820.1 4879454 D 331111 CDS YP_001465821.1 157155934 5586051 4882335..4882529 1 NC_009801.1 identified by similarity to GB:AAS76399.1; hypothetical protein 4882529 5586051 EcE24377A_4893 Escherichia coli E24377A hypothetical protein YP_001465821.1 4882335 D 331111 CDS YP_001465822.1 157154922 5588300 4882684..4883502 1 NC_009801.1 identified by similarity to GB:ABB61180.1; match to protein family HMM PF06067; hypothetical protein 4883502 5588300 EcE24377A_4894 Escherichia coli E24377A hypothetical protein YP_001465822.1 4882684 D 331111 CDS YP_001465823.1 157158137 5587028 4883844..4884317 1 NC_009801.1 identified by match to protein family HMM PF03230; antirestriction protein 4884317 5587028 EcE24377A_4895 Escherichia coli E24377A antirestriction protein YP_001465823.1 4883844 D 331111 CDS YP_001465824.1 157157651 5588357 4884333..4884809 1 NC_009801.1 identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608; RadC family DNA repair protein 4884809 5588357 EcE24377A_4896 Escherichia coli E24377A RadC family DNA repair protein YP_001465824.1 4884333 D 331111 CDS YP_001465825.1 157156636 5587493 4884872..4885093 1 NC_009801.1 identified by similarity to GB:AAP18295.1; match to protein family HMM PF06174; hypothetical protein 4885093 5587493 EcE24377A_4897 Escherichia coli E24377A hypothetical protein YP_001465825.1 4884872 D 331111 CDS YP_001465826.1 157156840 5587244 4885093..4885206 1 NC_009801.1 identified by similarity to GB:ABB61176.1; hypothetical protein 4885206 5587244 EcE24377A_4898 Escherichia coli E24377A hypothetical protein YP_001465826.1 4885093 D 331111 CDS YP_001465827.1 157155595 5590729 4885256..4885624 1 NC_009801.1 identified by similarity to GB:ABB61175.1; match to protein family HMM PF06154; hypothetical protein 4885624 5590729 EcE24377A_4899 Escherichia coli E24377A hypothetical protein YP_001465827.1 4885256 D 331111 CDS YP_001465828.1 157156412 5587164 4885714..4886088 1 NC_009801.1 identified by match to protein family HMM PF06755; hypothetical protein 4886088 5587164 EcE24377A_4900 Escherichia coli E24377A hypothetical protein YP_001465828.1 4885714 D 331111 CDS YP_001465829.1 157155868 5589202 4886085..4886576 1 NC_009801.1 identified by similarity to GB:ABB64452.1; hypothetical protein 4886576 5589202 EcE24377A_4901 Escherichia coli E24377A hypothetical protein YP_001465829.1 4886085 D 331111 CDS YP_001465830.1 157154990 5588292 4886593..4886769 1 NC_009801.1 identified by similarity to GB:ABB61172.1; match to protein family HMM PF06117; hypothetical protein 4886769 5588292 EcE24377A_4902 Escherichia coli E24377A hypothetical protein YP_001465830.1 4886593 D 331111 CDS YP_001465831.1 157158933 5586601 4887680..4890571 1 NC_009801.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04851; type III restriction enzyme, res subunit 4890571 5586601 EcE24377A_4903 Escherichia coli E24377A type III restriction enzyme, res subunit YP_001465831.1 4887680 D 331111 CDS YP_001465832.1 157158703 5586138 4890592..4893714 1 NC_009801.1 identified by match to protein family HMM PF01555; N4/N6-methyltransferase 4893714 5586138 EcE24377A_4904 Escherichia coli E24377A N4/N6-methyltransferase YP_001465832.1 4890592 D 331111 CDS YP_001465833.1 157158029 5589225 4893717..4897097 1 NC_009801.1 identified by glimmer; hypothetical protein 4897097 5589225 EcE24377A_4905 Escherichia coli E24377A hypothetical protein YP_001465833.1 4893717 D 331111 CDS YP_001465834.1 157158616 5589808 complement(4897759..4898631) 1 NC_009801.1 hypothetical protein 4898631 5589808 EcE24377A_4906 Escherichia coli E24377A hypothetical protein YP_001465834.1 4897759 R 331111 CDS YP_001465835.1 157158492 5589451 4898713..4898835 1 NC_009801.1 identified by glimmer; hypothetical protein 4898835 5589451 EcE24377A_4907 Escherichia coli E24377A hypothetical protein YP_001465835.1 4898713 D 331111 CDS YP_001465836.1 157157580 5587368 complement(4898843..4899823) 1 NC_009801.1 identified by match to protein family HMM PF03629; hypothetical protein 4899823 5587368 EcE24377A_4908 Escherichia coli E24377A hypothetical protein YP_001465836.1 4898843 R 331111 CDS YP_001465837.1 157158030 5589013 complement(4899888..4900994) 1 NC_009801.1 identified by match to protein family HMM PF01344; match to protein family HMM PF07646; N-acetylneuraminic acid mutarotase 4900994 5589013 EcE24377A_4909 Escherichia coli E24377A N-acetylneuraminic acid mutarotase YP_001465837.1 4899888 R 331111 CDS YP_001465838.1 157155937 5589809 complement(4901014..4901730) 1 NC_009801.1 identified by match to protein family HMM PF06178; oligogalacturonate-specific porin protein KdgM 4901730 5589809 EcE24377A_4910 Escherichia coli E24377A oligogalacturonate-specific porin protein KdgM YP_001465838.1 4901014 R 331111 CDS YP_001465839.1 157156560 5586373 complement(4902395..4902532) 1 NC_009801.1 identified by glimmer; hypothetical protein 4902532 5586373 EcE24377A_4911 Escherichia coli E24377A hypothetical protein YP_001465839.1 4902395 R 331111 CDS YP_001465840.1 157154948 5588962 4903155..4903430 1 NC_009801.1 identified by match to protein family HMM PF03811; IS1, transposase orfA 4903430 5588962 EcE24377A_4912 Escherichia coli E24377A IS1, transposase orfA YP_001465840.1 4903155 D 331111 CDS YP_001465841.1 157155515 5586603 4903349..4903843 1 NC_009801.1 identified by match to protein family HMM PF03400; IS1, transposase orfB 4903843 5586603 EcE24377A_4913 Escherichia coli E24377A IS1, transposase orfB YP_001465841.1 4903349 D 331111 CDS YP_001465842.1 157154995 5586016 4903891..4904751 1 NC_009801.1 identified by similarity to SP:P30130; match to protein family HMM PF00577; outer membrane usher protein FimD, truncation 4904751 5586016 EcE24377A_4914 Escherichia coli E24377A outer membrane usher protein FimD, truncation YP_001465842.1 4903891 D 331111 CDS YP_001465843.1 157155516 5590320 4904761..4905291 1 NC_009801.1 identified by similarity to SP:P08189; match to protein family HMM PF00419; protein FimF 4905291 fimF 5590320 fimF Escherichia coli E24377A protein FimF YP_001465843.1 4904761 D 331111 CDS YP_001465844.1 157157856 5586017 4905304..4905807 1 NC_009801.1 identified by similarity to SP:P08190; match to protein family HMM PF00419; protein fimG 4905807 fimG 5586017 fimG Escherichia coli E24377A protein fimG YP_001465844.1 4905304 D 331111 CDS YP_001465845.1 157157381 5589412 4905827..4906729 1 NC_009801.1 identified by match to protein family HMM PF00419; match to protein family HMM PF09160; protein FimH 4906729 fimH 5589412 fimH Escherichia coli E24377A protein FimH YP_001465845.1 4905827 D 331111 CDS YP_001465846.1 157156896 5590722 complement(4906777..4906881) 1 NC_009801.1 identified by glimmer; hypothetical protein 4906881 5590722 EcE24377A_4918 Escherichia coli E24377A hypothetical protein YP_001465846.1 4906777 R 331111 CDS YP_001465847.1 157156356 5586170 complement(4906902..4908245) 1 NC_009801.1 identified by similarity to SP:P0AC94; match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791; fructuronate transporter 4908245 gntP 5586170 gntP Escherichia coli E24377A fructuronate transporter YP_001465847.1 4906902 R 331111 CDS YP_001465848.1 157155131 5588499 4908585..4909769 1 NC_009801.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 4909769 uxuA 5588499 uxuA Escherichia coli E24377A mannonate dehydratase YP_001465848.1 4908585 D 331111 CDS YP_001465849.1 157157003 5586280 4909850..4911310 1 NC_009801.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125; mannitol dehydrogenase 4911310 5586280 EcE24377A_4921 Escherichia coli E24377A mannitol dehydrogenase YP_001465849.1 4909850 D 331111 CDS YP_001465850.1 157159139 5590292 complement(4911332..4911526) 1 NC_009801.1 identified by glimmer; hypothetical protein 4911526 5590292 EcE24377A_4922 Escherichia coli E24377A hypothetical protein YP_001465850.1 4911332 R 331111 CDS YP_001465851.1 157158470 5587675 4911525..4912298 1 NC_009801.1 regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 4912298 5587675 EcE24377A_4923 Escherichia coli E24377A DNA-binding transcriptional repressor UxuR YP_001465851.1 4911525 D 331111 CDS YP_001465852.1 157159458 5588469 4913788..4913931 1 NC_009801.1 identified by glimmer; hypothetical protein 4913931 5588469 EcE24377A_4924 Escherichia coli E24377A hypothetical protein YP_001465852.1 4913788 D 331111 CDS YP_001465853.1 157158205 5590870 4913900..4914289 1 NC_009801.1 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 4914289 iraD 5590870 iraD Escherichia coli E24377A DNA replication/recombination/repair protein YP_001465853.1 4913900 D 331111 CDS YP_001465854.1 157158792 5589673 complement(4914282..4915193) 1 NC_009801.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; DNA-binding transcriptional regulator 4915193 5589673 EcE24377A_4925 Escherichia coli E24377A DNA-binding transcriptional regulator YP_001465854.1 4914282 R 331111 CDS YP_001465855.1 157157626 5588066 complement(4915258..4916430) 1 NC_009801.1 identified by similarity to SP:P39377; match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR01975; isoaspartyl dipeptidase 4916430 iadA 5588066 iadA Escherichia coli E24377A isoaspartyl dipeptidase YP_001465855.1 4915258 R 331111 CDS YP_001465856.1 157159196 5586503 complement(4916443..4916904) 1 NC_009801.1 identified by match to protein family HMM PF07670; hypothetical protein 4916904 5586503 EcE24377A_4928 Escherichia coli E24377A hypothetical protein YP_001465856.1 4916443 R 331111 CDS YP_001465857.1 157158633 5589431 complement(4916901..4917584) 1 NC_009801.1 identified by match to protein family HMM PF07670; transporter 4917584 5589431 EcE24377A_4929 Escherichia coli E24377A transporter YP_001465857.1 4916901 R 331111 CDS YP_001465858.1 157158976 5587856 4917596..4917697 1 NC_009801.1 identified by glimmer; hypothetical protein 4917697 5587856 EcE24377A_4930 Escherichia coli E24377A hypothetical protein YP_001465858.1 4917596 D 331111 CDS YP_001465859.1 157158294 5589062 4917834..4918388 1 NC_009801.1 in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown; RNA 2'-phosphotransferase-like protein 4918388 kptA 5589062 kptA Escherichia coli E24377A RNA 2'-phosphotransferase-like protein YP_001465859.1 4917834 D 331111 CDS YP_001465860.1 157155917 5586890 complement(4918401..4919579) 1 NC_009801.1 identified by match to protein family HMM PF06779; match to protein family HMM PF07690; major facilitator transporter 4919579 5586890 EcE24377A_4932 Escherichia coli E24377A major facilitator transporter YP_001465860.1 4918401 R 331111 CDS YP_001465861.1 157155226 5589581 complement(4919647..4920618) 1 NC_009801.1 identified by match to protein family HMM PF06977; hypothetical protein 4920618 5589581 EcE24377A_4933 Escherichia coli E24377A hypothetical protein YP_001465861.1 4919647 R 331111 CDS YP_001465862.1 157158007 5589547 complement(4920572..4920829) 1 NC_009801.1 hypothetical protein 4920829 5589547 EcE24377A_4935 Escherichia coli E24377A hypothetical protein YP_001465862.1 4920572 R 331111 CDS YP_001465863.1 157157203 5588389 complement(4920826..4921593) 1 NC_009801.1 identified by similarity to SP:P11568; match to protein family HMM PF01869; match to protein family HMM TIGR00241; (R)-2-hydroxyglutaryl-CoA dehydratase activator 4921593 hgdC 5588389 hgdC Escherichia coli E24377A (R)-2-hydroxyglutaryl-CoA dehydratase activator YP_001465863.1 4920826 R 331111 CDS YP_001465864.1 157158686 5586749 complement(4921603..4922754) 1 NC_009801.1 identified by match to protein family HMM PF06050; 2-hydroxyglutaryl-CoA dehydratase subunit D 4922754 5586749 EcE24377A_4937 Escherichia coli E24377A 2-hydroxyglutaryl-CoA dehydratase subunit D YP_001465864.1 4921603 R 331111 CDS YP_001465865.1 157158478 5590314 complement(4922870..4924150) 1 NC_009801.1 identified by match to protein family HMM PF04286; hypothetical protein 4924150 5590314 EcE24377A_4938 Escherichia coli E24377A hypothetical protein YP_001465865.1 4922870 R 331111 CDS YP_001465866.1 157155043 5586999 complement(4924191..4925423) 1 NC_009801.1 identified by match to protein family HMM PF07690; multidrug resistance protein MdtM 4925423 mdtM 5586999 mdtM Escherichia coli E24377A multidrug resistance protein MdtM YP_001465866.1 4924191 R 331111 CDS YP_001465867.1 157159296 5589464 4925737..4926012 1 NC_009801.1 identified by match to protein family HMM PF03811; IS1, transposase orfA 4926012 5589464 EcE24377A_4940 Escherichia coli E24377A IS1, transposase orfA YP_001465867.1 4925737 D 331111 CDS YP_001465868.1 157157402 5588541 4926638..4926919 1 NC_009801.1 identified by similarity to GB:BAB72712.1; match to protein family HMM PF04365; hypothetical protein 4926919 5588541 EcE24377A_4942 Escherichia coli E24377A hypothetical protein YP_001465868.1 4926638 D 331111 CDS YP_001465869.1 157156716 5590783 4926906..4927208 1 NC_009801.1 identified by similarity to GB:AAV80076.1; hypothetical protein 4927208 5590783 EcE24377A_4943 Escherichia coli E24377A hypothetical protein YP_001465869.1 4926906 D 331111 CDS YP_001465870.1 157158071 5589873 complement(4927242..4928198) 1 NC_009801.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683; GTP-binding protein YjiA 4928198 5589873 EcE24377A_4944 Escherichia coli E24377A GTP-binding protein YjiA YP_001465870.1 4927242 R 331111 CDS YP_001465871.1 157157169 5587575 complement(4928209..4928412) 1 NC_009801.1 identified by similarity to SP:P0ADD1; match to protein family HMM PF04328; hypothetical protein 4928412 5587575 EcE24377A_4945 Escherichia coli E24377A hypothetical protein YP_001465871.1 4928209 R 331111 CDS YP_001465872.1 157154876 5586903 complement(4928462..4930627) 1 NC_009801.1 identified by match to protein family HMM PF02554; carbon starvation family protein 4930627 5586903 EcE24377A_4946 Escherichia coli E24377A carbon starvation family protein YP_001465872.1 4928462 R 331111 CDS YP_001465873.1 157155402 5587670 4930989..4932653 1 NC_009801.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203; methyl-accepting chemotaxis protein I 4932653 tsr 5587670 tsr Escherichia coli E24377A methyl-accepting chemotaxis protein I YP_001465873.1 4930989 D 331111 CDS YP_001465874.1 157155947 5587458 complement(4932702..4934063) 1 NC_009801.1 identified by match to protein family HMM PF07690; major facilitator transporter 4934063 5587458 EcE24377A_4948 Escherichia coli E24377A major facilitator transporter YP_001465874.1 4932702 R 331111 CDS YP_001465875.1 157156458 5587863 complement(4934278..4935192) 1 NC_009801.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729; GntR family transcriptional regulator 4935192 5587863 EcE24377A_4949 Escherichia coli E24377A GntR family transcriptional regulator YP_001465875.1 4934278 R 331111 CDS YP_001465876.1 157157641 5590709 4935205..4935297 1 NC_009801.1 identified by glimmer; hypothetical protein 4935297 5590709 EcE24377A_4950 Escherichia coli E24377A hypothetical protein YP_001465876.1 4935205 D 331111 CDS YP_001465877.1 157158167 5586241 4935331..4936353 1 NC_009801.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; zinc-binding dehydrogenase oxidoreductase 4936353 5586241 EcE24377A_4951 Escherichia coli E24377A zinc-binding dehydrogenase oxidoreductase YP_001465877.1 4935331 D 331111 CDS YP_001465878.1 157158691 5588948 complement(4936493..4938784) 1 NC_009801.1 catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I 4938784 mdoB 5588948 mdoB Escherichia coli E24377A phosphoglycerol transferase I YP_001465878.1 4936493 R 331111 CDS YP_001465879.1 157159219 5588289 complement(4939038..4939535) 1 NC_009801.1 hypothetical protein 4939535 5588289 EcE24377A_4953 Escherichia coli E24377A hypothetical protein YP_001465879.1 4939038 R 331111 CDS YP_001465880.1 157159028 5586665 complement(4939581..4940318) 1 NC_009801.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 4940318 dnaC 5586665 dnaC Escherichia coli E24377A DNA replication protein DnaC YP_001465880.1 4939581 R 331111 CDS YP_001465881.1 157156875 5589437 complement(4940321..4940860) 1 NC_009801.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 4940860 dnaT 5589437 dnaT Escherichia coli E24377A primosomal protein DnaI YP_001465881.1 4940321 R 331111 CDS YP_001465882.2 229220659 5588124 complement(4940967..4941440) 1 NC_009801.1 hypothetical protein 4941440 5588124 EcE24377A_4956 Escherichia coli E24377A hypothetical protein YP_001465882.2 4940967 R 331111 CDS YP_001465883.1 157157486 5589114 complement(4941431..4942264) 1 NC_009801.1 identified by match to protein family HMM PF06738; hypothetical protein 4942264 5589114 EcE24377A_4957 Escherichia coli E24377A hypothetical protein YP_001465883.1 4941431 R 331111 CDS YP_001465884.1 157154873 5588377 4942503..4942604 1 NC_009801.1 identified by glimmer; hypothetical protein 4942604 5588377 EcE24377A_4958 Escherichia coli E24377A hypothetical protein YP_001465884.1 4942503 D 331111 CDS YP_001465885.1 157155541 5587591 4942822..4943547 1 NC_009801.1 identified by match to protein family HMM PF00196; LuxR family transcriptional regulator 4943547 5587591 EcE24377A_4959 Escherichia coli E24377A LuxR family transcriptional regulator YP_001465885.1 4942822 D 331111 CDS YP_001465886.1 157156569 5589465 4943505..4944182 1 NC_009801.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 4944182 5589465 EcE24377A_4960 Escherichia coli E24377A DNA-binding transcriptional activator BglJ YP_001465886.1 4943505 D 331111 CDS YP_001465887.1 157154806 5588550 complement(4944220..4945008) 1 NC_009801.1 identified by similarity to SP:P39405; match to protein family HMM PF06276; ferric hydroximate transport ferric iron reductase 4945008 fhuF 5588550 fhuF Escherichia coli E24377A ferric hydroximate transport ferric iron reductase YP_001465887.1 4944220 R 331111 CDS YP_001465888.1 157158190 5585957 4945038..4945385 1 NC_009801.1 identified by similarity to GB:AAN83867.1; match to protein family HMM PF07256; hypothetical protein 4945385 5585957 EcE24377A_4962 Escherichia coli E24377A hypothetical protein YP_001465888.1 4945038 D 331111 CDS YP_001465889.1 157156493 5588606 complement(4946014..4947045) 1 NC_009801.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 4947045 rsmC 5588606 rsmC Escherichia coli E24377A 16S ribosomal RNA m2G1207 methyltransferase YP_001465889.1 4946014 R 331111 CDS YP_001465890.1 157157679 5588924 4947148..4947561 1 NC_009801.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 4947561 holD 5588924 holD Escherichia coli E24377A DNA polymerase III subunit psi YP_001465890.1 4947148 D 331111 CDS YP_001465891.1 157157101 5590550 4947530..4947976 1 NC_009801.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 4947976 rimI 5590550 rimI Escherichia coli E24377A ribosomal-protein-alanine N-acetyltransferase YP_001465891.1 4947530 D 331111 CDS YP_001465892.1 157157787 5586377 4947991..4948668 1 NC_009801.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 4948668 yjjG 5586377 yjjG Escherichia coli E24377A nucleotidase YP_001465892.1 4947991 D 331111 CDS YP_001465893.1 157157149 5589422 complement(4948495..4949985) 1 NC_009801.1 identified by glimmer; hypothetical protein 4949985 5589422 EcE24377A_4969 Escherichia coli E24377A hypothetical protein YP_001465893.1 4948495 R 331111 CDS YP_001465894.1 157159306 5588985 4948759..4950348 1 NC_009801.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 4950348 prfC 5588985 prfC Escherichia coli E24377A peptide chain release factor 3 YP_001465894.1 4948759 D 331111 CDS YP_001465895.1 157159050 5588479 complement(4950708..4951400) 1 NC_009801.1 identified by glimmer; hypothetical protein 4951400 5588479 EcE24377A_4972 Escherichia coli E24377A hypothetical protein YP_001465895.1 4950708 R 331111 CDS YP_001465896.1 157155787 5588698 4950741..4951346 1 NC_009801.1 identified by similarity to SP:P27291; match to protein family HMM PF04972; hypothetical protein 4951346 osmY 5588698 osmY Escherichia coli E24377A hypothetical protein YP_001465896.1 4950741 D 331111 CDS YP_001465897.1 157158627 5587630 4951473..4951634 1 NC_009801.1 identified by glimmer; hypothetical protein 4951634 5587630 EcE24377A_4974 Escherichia coli E24377A hypothetical protein YP_001465897.1 4951473 D 331111 CDS YP_001465898.1 157156545 5588929 4951756..4952829 1 NC_009801.1 identified by match to protein family HMM PF01734; patatin family phospholipase 4952829 5588929 EcE24377A_4975 Escherichia coli E24377A patatin family phospholipase YP_001465898.1 4951756 D 331111 CDS YP_001465899.1 157155194 5590199 4952826..4953608 1 NC_009801.1 identified by match to protein family HMM PF01026; deoxyribonuclease YjjV 4953608 5590199 EcE24377A_4976 Escherichia coli E24377A deoxyribonuclease YjjV YP_001465899.1 4952826 D 331111 CDS YP_001465900.1 157157888 5588163 complement(4953721..4954584) 1 NC_009801.1 identified by match to protein family HMM PF00037; match to protein family HMM PF04055; radical SAM domain-containing protein 4954584 5588163 EcE24377A_4977 Escherichia coli E24377A radical SAM domain-containing protein YP_001465900.1 4953721 R 331111 CDS YP_001465901.1 157157718 5588716 complement(4954556..4956106) 1 NC_009801.1 yjjI; hypothetical protein 4956106 5588716 EcE24377A_4978 Escherichia coli E24377A hypothetical protein YP_001465901.1 4954556 R 331111 CDS YP_001465902.1 157159133 5590627 4956082..4956207 1 NC_009801.1 hypothetical protein 4956207 5590627 EcE24377A_4979 Escherichia coli E24377A hypothetical protein YP_001465902.1 4956082 D 331111 CDS YP_001465903.1 157157234 5588059 4956364..4957143 1 NC_009801.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 4957143 deoC 5588059 deoC Escherichia coli E24377A deoxyribose-phosphate aldolase YP_001465903.1 4956364 D 331111 CDS YP_001465904.1 157155669 5588086 4957270..4958592 1 NC_009801.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 4958592 deoA 5588086 deoA Escherichia coli E24377A thymidine phosphorylase YP_001465904.1 4957270 D 331111 CDS YP_001465905.1 157158525 5587262 4958644..4959867 1 NC_009801.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 4959867 deoB 5587262 deoB Escherichia coli E24377A phosphopentomutase YP_001465905.1 4958644 D 331111 CDS YP_001465906.1 157155627 5588156 4959947..4960666 1 NC_009801.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 4960666 deoD 5588156 deoD Escherichia coli E24377A purine nucleoside phosphorylase YP_001465906.1 4959947 D 331111 CDS YP_001465907.1 157157103 5589643 complement(4961122..4962138) 1 NC_009801.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A 4962138 lplA 5589643 lplA Escherichia coli E24377A lipoate-protein ligase A YP_001465907.1 4961122 R 331111 CDS YP_001465908.1 157157208 5586757 complement(4962166..4962810) 1 NC_009801.1 hypothetical protein 4962810 5586757 EcE24377A_4986 Escherichia coli E24377A hypothetical protein YP_001465908.1 4962166 R 331111 CDS YP_001465909.1 157158019 5586621 4962916..4963884 1 NC_009801.1 catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 4963884 serB 5586621 serB Escherichia coli E24377A phosphoserine phosphatase YP_001465909.1 4962916 D 331111 CDS YP_001465910.1 157158867 5588978 4963933..4965315 1 NC_009801.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4965315 radA 5588978 radA Escherichia coli E24377A DNA repair protein RadA YP_001465910.1 4963933 D 331111 CDS YP_001465911.1 157159415 5588559 4965336..4966568 1 NC_009801.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 4966568 nadR 5588559 nadR Escherichia coli E24377A nicotinamide-nucleotide adenylyltransferase YP_001465911.1 4965336 D 331111 CDS YP_001465912.1 157157432 5586025 complement(4966875..4968542) 1 NC_009801.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 4968542 5586025 EcE24377A_4990 Escherichia coli E24377A ABC transporter ATP-binding protein YP_001465912.1 4966875 R 331111 CDS YP_001465913.1 157157903 5590397 4968753..4970690 1 NC_009801.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 4970690 slt 5590397 slt Escherichia coli E24377A lytic murein transglycosylase YP_001465913.1 4968753 D 331111 CDS YP_001465914.1 157156215 5590440 4970780..4971106 1 NC_009801.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 4971106 trpR 5590440 trpR Escherichia coli E24377A Trp operon repressor YP_001465914.1 4970780 D 331111 CDS YP_001465915.1 157156773 5586418 complement(4971191..4971721) 1 NC_009801.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 4971721 5586418 EcE24377A_4993 Escherichia coli E24377A NTPase YP_001465915.1 4971191 R 331111 CDS YP_001465916.1 157154825 5589153 4971764..4972411 1 NC_009801.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 4972411 5589153 EcE24377A_4995 Escherichia coli E24377A phosphoglycerate mutase YP_001465916.1 4971764 D 331111 CDS YP_001465917.1 157156444 5586663 complement(4972408..4973277) 1 NC_009801.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445; right origin-binding protein 4973277 rob 5586663 rob Escherichia coli E24377A right origin-binding protein YP_001465917.1 4972408 R 331111 CDS YP_001465918.1 157159370 5587486 4973488..4973961 1 NC_009801.1 identified by match to protein family HMM PF05981; hypothetical protein 4973961 5587486 EcE24377A_4996 Escherichia coli E24377A hypothetical protein YP_001465918.1 4973488 D 331111 CDS YP_001465919.1 157158943 5589619 4973974..4974663 1 NC_009801.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 4974663 creB 5589619 creB Escherichia coli E24377A DNA-binding response regulator CreB YP_001465919.1 4973974 D 331111 CDS YP_001465920.1 157159288 5587291 4974663..4976087 1 NC_009801.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 4976087 creC 5587291 creC Escherichia coli E24377A sensory histidine kinase CreC YP_001465920.1 4974663 D 331111 CDS YP_001465921.1 157158612 5588100 4976145..4977497 1 NC_009801.1 identified by match to protein family HMM PF06123; hypothetical protein 4977497 5588100 EcE24377A_4999 Escherichia coli E24377A hypothetical protein YP_001465921.1 4976145 D 331111 CDS YP_001465922.1 157155557 5589070 complement(4977557..4978273) 1 NC_009801.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; two-component response regulator 4978273 arcA 5589070 arcA Escherichia coli E24377A two-component response regulator YP_001465922.1 4977557 R 331111 CDS YP_001465923.1 157154933 5590436 4978369..4978509 1 NC_009801.1 identified by similarity to GB:AAV80131.1; hypothetical protein 4978509 5590436 EcE24377A_5001 Escherichia coli E24377A hypothetical protein YP_001465923.1 4978369 D 331111 CDS YP_001465924.1 157156588 5589935 4978909..4979595 1 NC_009801.1 member of the SPOUT superfamily of methyltransferases; RNA methyltransferase 4979595 5589935 EcE24377A_5002 Escherichia coli E24377A RNA methyltransferase YP_001465924.1 4978909 D 331111 CDS