-- dump date   	20140619_074407
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
768486000001	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
768486000002	active site
768486000003	catalytic site [active]
768486000004	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
768486000005	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486000006	non-specific DNA binding site [nucleotide binding]; other site
768486000007	salt bridge; other site
768486000008	sequence-specific DNA binding site [nucleotide binding]; other site
768486000009	Conjugative transposon protein TcpC; Region: TpcC; pfam12642
768486000010	TcpE family; Region: TcpE; pfam12648
768486000011	AAA-like domain; Region: AAA_10; pfam12846
768486000012	Domain of unknown function DUF87; Region: DUF87; pfam01935
768486000013	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; pfam04610
768486000014	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
768486000015	Peptidase family M23; Region: Peptidase_M23; pfam01551
768486000016	DNA polymerase IV; Reviewed; Region: PRK03103
768486000017	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
768486000018	active site
768486000019	DNA binding site [nucleotide binding]
768486000020	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
768486000021	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
768486000022	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
768486000023	P-loop; other site
768486000024	Magnesium ion binding site [ion binding]; other site
768486000025	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
768486000026	Magnesium ion binding site [ion binding]; other site
768486000027	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486000028	Coenzyme A binding pocket [chemical binding]; other site
768486000029	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486000030	non-specific DNA binding site [nucleotide binding]; other site
768486000031	salt bridge; other site
768486000032	sequence-specific DNA binding site [nucleotide binding]; other site
768486000033	Bacterial protein of unknown function (DUF961); Region: DUF961; pfam06125
768486000034	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
768486000035	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486000036	non-specific DNA binding site [nucleotide binding]; other site
768486000037	salt bridge; other site
768486000038	sequence-specific DNA binding site [nucleotide binding]; other site
768486000039	Replication initiation factor; Region: Rep_trans; pfam02486
768486000040	Pollen proteins Ole e I like; Region: Pollen_Ole_e_I; pfam01190
768486000041	Mga helix-turn-helix domain; Region: Mga; pfam05043
768486000042	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
768486000043	DNA-binding site [nucleotide binding]; DNA binding site
768486000044	RNA-binding motif; other site
768486000045	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
768486000046	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
768486000047	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
768486000048	Predicted membrane protein [Function unknown]; Region: COG2246
768486000049	GtrA-like protein; Region: GtrA; pfam04138
768486000050	Protein of unknown function (DUF1189); Region: DUF1189; pfam06691
768486000051	Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family; Region: PGDH_1; cd12155
768486000052	glycerate dehydrogenase; Provisional; Region: PRK06932
768486000053	putative ligand binding site [chemical binding]; other site
768486000054	NAD binding site [chemical binding]; other site
768486000055	catalytic site [active]
768486000056	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
768486000057	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
768486000058	TrkA-N domain; Region: TrkA_N; pfam02254
768486000059	TrkA-C domain; Region: TrkA_C; pfam02080
768486000060	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
768486000061	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486000062	active site
768486000063	phosphorylation site [posttranslational modification]
768486000064	intermolecular recognition site; other site
768486000065	dimerization interface [polypeptide binding]; other site
768486000066	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
768486000067	DNA binding residues [nucleotide binding]
768486000068	dimerization interface [polypeptide binding]; other site
768486000069	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
768486000070	Histidine kinase; Region: HisKA_3; pfam07730
768486000071	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
768486000072	ATP binding site [chemical binding]; other site
768486000073	Mg2+ binding site [ion binding]; other site
768486000074	G-X-G motif; other site
768486000075	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
768486000076	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
768486000077	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
768486000078	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
768486000079	YceG-like family; Region: YceG; pfam02618
768486000080	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
768486000081	dimerization interface [polypeptide binding]; other site
768486000082	Beta-lactamase; Region: Beta-lactamase; pfam00144
768486000083	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
768486000084	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
768486000085	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
768486000086	NAD(P) binding site [chemical binding]; other site
768486000087	active site
768486000088	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
768486000089	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
768486000090	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
768486000091	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
768486000092	Probable Catalytic site; other site
768486000093	LicD family; Region: LicD; cl01378
768486000094	O-Antigen ligase; Region: Wzy_C; pfam04932
768486000095	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
768486000096	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
768486000097	active site
768486000098	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
768486000099	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
768486000100	NAD(P) binding site [chemical binding]; other site
768486000101	active site
768486000102	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
768486000103	substrate binding site; other site
768486000104	dimer interface; other site
768486000105	AtlA is an autolysin found in Gram-positive lactic acid bacteria that degrades bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family includes the AtlA and Aml...; Region: GH25_AtlA-like; cd06522
768486000106	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
768486000107	active site
768486000108	LicD family; Region: LicD; cl01378
768486000109	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
768486000110	active site
768486000111	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
768486000112	Bacterial sugar transferase; Region: Bac_transf; pfam02397
768486000113	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
768486000114	Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; Region: GT2_RfbC_Mx_like; cd04184
768486000115	Probable Catalytic site; other site
768486000116	metal-binding site
768486000117	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
768486000118	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
768486000119	Probable Catalytic site; other site
768486000120	metal-binding site
768486000121	Methyltransferase domain; Region: Methyltransf_23; pfam13489
768486000122	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486000123	S-adenosylmethionine binding site [chemical binding]; other site
768486000124	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
768486000125	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
768486000126	Walker A/P-loop; other site
768486000127	ATP binding site [chemical binding]; other site
768486000128	Q-loop/lid; other site
768486000129	ABC transporter signature motif; other site
768486000130	Walker B; other site
768486000131	D-loop; other site
768486000132	H-loop/switch region; other site
768486000133	C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147
768486000134	putative carbohydrate binding site [chemical binding]; other site
768486000135	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
768486000136	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
768486000137	O-antigen ligase like membrane protein; Region: O-antigen_lig; pfam13425
768486000138	MULE transposase domain; Region: MULE; pfam10551
768486000139	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
768486000140	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
768486000141	NADP binding site [chemical binding]; other site
768486000142	active site
768486000143	putative substrate binding site [chemical binding]; other site
768486000144	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
768486000145	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
768486000146	NAD binding site [chemical binding]; other site
768486000147	substrate binding site [chemical binding]; other site
768486000148	homodimer interface [polypeptide binding]; other site
768486000149	active site
768486000150	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
768486000151	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
768486000152	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
768486000153	substrate binding site; other site
768486000154	tetramer interface; other site
768486000155	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
768486000156	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
768486000157	Probable Catalytic site; other site
768486000158	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
768486000159	active site
768486000160	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
768486000161	active site
768486000162	Glycosyltransferase like family; Region: Glyco_tranf_2_5; pfam13712
768486000163	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
768486000164	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
768486000165	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
768486000166	Mg++ binding site [ion binding]; other site
768486000167	putative catalytic motif [active]
768486000168	substrate binding site [chemical binding]; other site
768486000169	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
768486000170	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
768486000171	active site
768486000172	flavodoxin; Validated; Region: PRK07308
768486000173	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
768486000174	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
768486000175	WHG domain; Region: WHG; pfam13305
768486000176	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
768486000177	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
768486000178	Acetyltransferase (GNAT) domain; Region: Acetyltransf_9; pfam13527
768486000179	Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only]; Region: Eis; COG4552
768486000180	Domain of unknown function (DUF3284); Region: DUF3284; pfam11687
768486000181	Protein of unknown function (DUF3188); Region: DUF3188; pfam11384
768486000182	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
768486000183	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
768486000184	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
768486000185	active site
768486000186	methionine cluster; other site
768486000187	phosphorylation site [posttranslational modification]
768486000188	metal binding site [ion binding]; metal-binding site
768486000189	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
768486000190	active site
768486000191	P-loop; other site
768486000192	phosphorylation site [posttranslational modification]
768486000193	potential frameshift: common BLAST hit: gi|29375591|ref|NP_814745.1| sigma-54 factor interaction domain-containing protein
768486000194	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
768486000195	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
768486000196	ATP binding site [chemical binding]; other site
768486000197	putative Mg++ binding site [ion binding]; other site
768486000198	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
768486000199	nucleotide binding region [chemical binding]; other site
768486000200	ATP-binding site [chemical binding]; other site
768486000201	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
768486000202	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
768486000203	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
768486000204	Mn-dependent transcriptional regulator [Transcription]; Region: TroR; COG1321
768486000205	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
768486000206	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
768486000207	FeoA domain; Region: FeoA; pfam04023
768486000208	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
768486000209	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
768486000210	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
768486000211	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
768486000212	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
768486000213	active site
768486000214	HIGH motif; other site
768486000215	nucleotide binding site [chemical binding]; other site
768486000216	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
768486000217	active site
768486000218	KMSKS motif; other site
768486000219	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
768486000220	tRNA binding surface [nucleotide binding]; other site
768486000221	anticodon binding site; other site
768486000222	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
768486000223	DivIVA protein; Region: DivIVA; pfam05103
768486000224	DivIVA domain; Region: DivI1A_domain; TIGR03544
768486000225	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
768486000226	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
768486000227	RNA binding surface [nucleotide binding]; other site
768486000228	YGGT family; Region: YGGT; pfam02325
768486000229	Protein of unknown function (DUF552); Region: DUF552; pfam04472
768486000230	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
768486000231	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
768486000232	catalytic residue [active]
768486000233	cell division protein FtsZ; Validated; Region: PRK09330
768486000234	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
768486000235	nucleotide binding site [chemical binding]; other site
768486000236	SulA interaction site; other site
768486000237	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
768486000238	Cell division protein FtsA; Region: FtsA; smart00842
768486000239	Cell division protein FtsA; Region: FtsA; pfam14450
768486000240	Domain of unknown function (DUF3484); Region: DUF3484; pfam11983
768486000241	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
768486000242	Cell division protein FtsQ; Region: FtsQ; pfam03799
768486000243	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
768486000244	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
768486000245	active site
768486000246	homodimer interface [polypeptide binding]; other site
768486000247	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
768486000248	Alanine dehydrogenase/PNT, C-terminal domain; Region: AlaDh_PNT_C; smart01002
768486000249	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
768486000250	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
768486000251	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
768486000252	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
768486000253	Mg++ binding site [ion binding]; other site
768486000254	putative catalytic motif [active]
768486000255	putative substrate binding site [chemical binding]; other site
768486000256	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
768486000257	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
768486000258	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
768486000259	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
768486000260	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
768486000261	Cell division protein FtsL; Region: FtsL; cl11433
768486000262	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
768486000263	MraW methylase family; Region: Methyltransf_5; pfam01795
768486000264	cell division protein MraZ; Reviewed; Region: PRK00326
768486000265	MraZ protein; Region: MraZ; pfam02381
768486000266	MraZ protein; Region: MraZ; pfam02381
768486000267	Protein of unknown function (DUF3397); Region: DUF3397; pfam11877
768486000268	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
768486000269	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
768486000270	Cl binding site [ion binding]; other site
768486000271	oligomer interface [polypeptide binding]; other site
768486000272	Protein of unknown function (DUF4044); Region: DUF4044; pfam13253
768486000273	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
768486000274	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
768486000275	Walker A/P-loop; other site
768486000276	ATP binding site [chemical binding]; other site
768486000277	Q-loop/lid; other site
768486000278	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
768486000279	ABC transporter signature motif; other site
768486000280	Walker B; other site
768486000281	D-loop; other site
768486000282	H-loop/switch region; other site
768486000283	Arginine repressor [Transcription]; Region: ArgR; COG1438
768486000284	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
768486000285	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
768486000286	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
768486000287	S4 RNA-binding domain; Region: S4; smart00363
768486000288	RNA binding surface [nucleotide binding]; other site
768486000289	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
768486000290	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
768486000291	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
768486000292	substrate binding pocket [chemical binding]; other site
768486000293	chain length determination region; other site
768486000294	substrate-Mg2+ binding site; other site
768486000295	catalytic residues [active]
768486000296	aspartate-rich region 1; other site
768486000297	active site lid residues [active]
768486000298	aspartate-rich region 2; other site
768486000299	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
768486000300	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
768486000301	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
768486000302	generic binding surface II; other site
768486000303	generic binding surface I; other site
768486000304	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
768486000305	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14179
768486000306	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
768486000307	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
768486000308	homodimer interface [polypeptide binding]; other site
768486000309	NADP binding site [chemical binding]; other site
768486000310	substrate binding site [chemical binding]; other site
768486000311	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
768486000312	putative RNA binding site [nucleotide binding]; other site
768486000313	Asp23 family; Region: Asp23; pfam03780
768486000314	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
768486000315	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
768486000316	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
768486000317	active site
768486000318	Predicted membrane protein [Function unknown]; Region: COG2261
768486000319	Domain of unknown function (DUF956); Region: DUF956; pfam06115
768486000320	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
768486000321	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
768486000322	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
768486000323	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
768486000324	active pocket/dimerization site; other site
768486000325	active site
768486000326	phosphorylation site [posttranslational modification]
768486000327	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
768486000328	active site
768486000329	phosphorylation site [posttranslational modification]
768486000330	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
768486000331	active site
768486000332	phosphorylation site [posttranslational modification]
768486000333	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
768486000334	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486000335	Walker A motif; other site
768486000336	ATP binding site [chemical binding]; other site
768486000337	Walker B motif; other site
768486000338	arginine finger; other site
768486000339	Transcriptional antiterminator [Transcription]; Region: COG3933
768486000340	PRD domain; Region: PRD; pfam00874
768486000341	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
768486000342	active pocket/dimerization site; other site
768486000343	active site
768486000344	phosphorylation site [posttranslational modification]
768486000345	PRD domain; Region: PRD; pfam00874
768486000346	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
768486000347	Acyltransferase family; Region: Acyl_transf_3; pfam01757
768486000348	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
768486000349	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
768486000350	DNA-binding site [nucleotide binding]; DNA binding site
768486000351	RNA-binding motif; other site
768486000352	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
768486000353	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
768486000354	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
768486000355	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
768486000356	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
768486000357	active site
768486000358	Phage holin; Region: Phage_holin_5; pfam06946
768486000359	Domain of unknown function (DUF2479); Region: DUF2479; pfam10651
768486000360	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
768486000361	active site
768486000362	catalytic triad [active]
768486000363	oxyanion hole [active]
768486000364	Prophage endopeptidase tail; Region: Prophage_tail; pfam06605
768486000365	Phage tail protein; Region: Sipho_tail; pfam05709
768486000366	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
768486000367	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
768486000368	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
768486000369	N-acetyl-D-glucosamine binding site [chemical binding]; other site
768486000370	catalytic residue [active]
768486000371	HeH/LEM domain; Region: HeH; pfam12949
768486000372	phage major tail protein, phi13 family; Region: maj_tail_phi13; TIGR01603
768486000373	HeH/LEM domain; Region: HeH; pfam12949
768486000374	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
768486000375	Phage capsid family; Region: Phage_capsid; pfam05065
768486000376	ATP-dependent Clp protease proteolytic subunit; Provisional; Region: PRK14512
768486000377	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
768486000378	oligomer interface [polypeptide binding]; other site
768486000379	active site residues [active]
768486000380	Phage-related protein [Function unknown]; Region: COG4695
768486000381	Phage portal protein; Region: Phage_portal; pfam04860
768486000382	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
768486000383	Phage terminase, small subunit; Region: Terminase_4; cl01525
768486000384	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
768486000385	active site
768486000386	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
768486000387	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
768486000388	ORF6C domain; Region: ORF6C; pfam10552
768486000389	Protein of unknown function (DUF1642); Region: DUF1642; pfam07852
768486000390	YopX protein; Region: YopX; pfam09643
768486000391	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486000392	AAA domain; Region: AAA_22; pfam13401
768486000393	Walker A motif; other site
768486000394	ATP binding site [chemical binding]; other site
768486000395	Walker B motif; other site
768486000396	Replication initiation and membrane attachment; Region: DnaB_2; cl12121
768486000397	Helix-turn-helix domain; Region: HTH_36; pfam13730
768486000398	Replication initiation and membrane attachment; Region: DnaB_2; cl12121
768486000399	RecT family; Region: RecT; cl04285
768486000400	YqaJ-like viral recombinase domain; Region: YqaJ; cl09232
768486000401	Uncharacterized protein conserved in bacteria (DUF2321); Region: DUF2321; pfam10083
768486000402	Protein of unknown function (DUF2829); Region: DUF2829; pfam11195
768486000403	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486000404	non-specific DNA binding site [nucleotide binding]; other site
768486000405	salt bridge; other site
768486000406	sequence-specific DNA binding site [nucleotide binding]; other site
768486000407	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
768486000408	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486000409	non-specific DNA binding site [nucleotide binding]; other site
768486000410	salt bridge; other site
768486000411	sequence-specific DNA binding site [nucleotide binding]; other site
768486000412	Domain of unknown function (DUF955); Region: DUF955; pfam06114
768486000413	DNA polymerase III subunit epsilon; Validated; Region: PRK06195
768486000414	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
768486000415	active site
768486000416	catalytic site [active]
768486000417	substrate binding site [chemical binding]; other site
768486000418	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
768486000419	Dimer interface [polypeptide binding]; other site
768486000420	Domain of unknown function (DUF4352); Region: DUF4352; pfam11611
768486000421	integrase; Provisional; Region: PRK09692
768486000422	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
768486000423	Int/Topo IB signature motif; other site
768486000424	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
768486000425	Protein of unknown function (DUF464); Region: DUF464; pfam04327
768486000426	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
768486000427	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
768486000428	active site
768486000429	Fe-S cluster binding site [ion binding]; other site
768486000430	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
768486000431	Sulfate transporter family; Region: Sulfate_transp; pfam00916
768486000432	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
768486000433	Predicted membrane protein [Function unknown]; Region: COG3759
768486000434	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
768486000435	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486000436	S-adenosylmethionine binding site [chemical binding]; other site
768486000437	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
768486000438	Catalytic site [active]
768486000439	potential frameshift: common BLAST hit: gi|389867942|ref|YP_006375365.1| TerC family integral membrane protein
768486000440	potential frameshift: common BLAST hit: gi|389867942|ref|YP_006375365.1| TerC family integral membrane protein
768486000441	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
768486000442	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
768486000443	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
768486000444	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
768486000445	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
768486000446	Protein of unknown function (DUF975); Region: DUF975; cl10504
768486000447	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
768486000448	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
768486000449	oligomer interface [polypeptide binding]; other site
768486000450	active site
768486000451	metal binding site [ion binding]; metal-binding site
768486000452	D-alanyl-lipoteichoic acid biosynthesis protein DltD; Region: LTA_DltD; TIGR04092
768486000453	DltD N-terminal region; Region: DltD_N; pfam04915
768486000454	DltD central region; Region: DltD_M; pfam04918
768486000455	DltD C-terminal region; Region: DltD_C; pfam04914
768486000456	D-alanine--poly(phosphoribitol) ligase subunit 2; Validated; Region: PRK05087
768486000457	D-alanyl-lipoteichoic acid biosynthesis protein DltB; Region: LTA_dltB; TIGR04091
768486000458	D-alanine--poly(phosphoribitol) ligase subunit 1; Provisional; Region: PRK04813
768486000459	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
768486000460	acyl-activating enzyme (AAE) consensus motif; other site
768486000461	AMP binding site [chemical binding]; other site
768486000462	D-Ala-teichoic acid biosynthesis protein; Region: DUF3687; pfam12459
768486000463	potential frameshift: common BLAST hit: gi|389867932|ref|YP_006375355.1| ABC superfamily ATP binding cassette transporter, membrane protein
768486000464	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
768486000465	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
768486000466	Walker A/P-loop; other site
768486000467	ATP binding site [chemical binding]; other site
768486000468	Q-loop/lid; other site
768486000469	ABC transporter signature motif; other site
768486000470	Walker B; other site
768486000471	D-loop; other site
768486000472	H-loop/switch region; other site
768486000473	potential frameshift: common BLAST hit: gi|332686125|ref|YP_004455899.1| ribonucleotide reductase of class III (anaerobic), large subunit
768486000474	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
768486000475	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
768486000476	potential frameshift: common BLAST hit: gi|389867928|ref|YP_006375351.1| DNA-directed DNA polymerase IV
768486000477	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
768486000478	DNA polymerase IV; Validated; Region: PRK02406
768486000479	active site
768486000480	DNA binding site [nucleotide binding]
768486000481	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
768486000482	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
768486000483	CoA binding domain; Region: CoA_binding; pfam02629
768486000484	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
768486000485	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486000486	Walker A/P-loop; other site
768486000487	ATP binding site [chemical binding]; other site
768486000488	Q-loop/lid; other site
768486000489	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
768486000490	ABC transporter signature motif; other site
768486000491	Walker B; other site
768486000492	D-loop; other site
768486000493	ABC transporter; Region: ABC_tran_2; pfam12848
768486000494	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
768486000495	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
768486000496	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
768486000497	Walker A/P-loop; other site
768486000498	ATP binding site [chemical binding]; other site
768486000499	Q-loop/lid; other site
768486000500	ABC transporter signature motif; other site
768486000501	Walker B; other site
768486000502	D-loop; other site
768486000503	H-loop/switch region; other site
768486000504	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
768486000505	FtsX-like permease family; Region: FtsX; pfam02687
768486000506	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
768486000507	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486000508	active site
768486000509	phosphorylation site [posttranslational modification]
768486000510	intermolecular recognition site; other site
768486000511	dimerization interface [polypeptide binding]; other site
768486000512	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
768486000513	DNA binding site [nucleotide binding]
768486000514	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
768486000515	dimer interface [polypeptide binding]; other site
768486000516	phosphorylation site [posttranslational modification]
768486000517	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
768486000518	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
768486000519	ATP binding site [chemical binding]; other site
768486000520	Mg2+ binding site [ion binding]; other site
768486000521	G-X-G motif; other site
768486000522	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
768486000523	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
768486000524	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486000525	Walker A/P-loop; other site
768486000526	ATP binding site [chemical binding]; other site
768486000527	Q-loop/lid; other site
768486000528	ABC transporter signature motif; other site
768486000529	Walker B; other site
768486000530	D-loop; other site
768486000531	H-loop/switch region; other site
768486000532	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
768486000533	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
768486000534	putative Zn2+ binding site [ion binding]; other site
768486000535	putative DNA binding site [nucleotide binding]; other site
768486000536	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
768486000537	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
768486000538	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
768486000539	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486000540	dimer interface [polypeptide binding]; other site
768486000541	conserved gate region; other site
768486000542	putative PBP binding loops; other site
768486000543	ABC-ATPase subunit interface; other site
768486000544	2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050
768486000545	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486000546	dimer interface [polypeptide binding]; other site
768486000547	conserved gate region; other site
768486000548	putative PBP binding loops; other site
768486000549	ABC-ATPase subunit interface; other site
768486000550	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
768486000551	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
768486000552	Walker A/P-loop; other site
768486000553	ATP binding site [chemical binding]; other site
768486000554	Q-loop/lid; other site
768486000555	ABC transporter signature motif; other site
768486000556	Walker B; other site
768486000557	D-loop; other site
768486000558	H-loop/switch region; other site
768486000559	TOBE domain; Region: TOBE_2; pfam08402
768486000560	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
768486000561	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486000562	non-specific DNA binding site [nucleotide binding]; other site
768486000563	salt bridge; other site
768486000564	sequence-specific DNA binding site [nucleotide binding]; other site
768486000565	Yhdh and yhfp-like putative quinone oxidoreductases; Region: MDR_yhdh_yhfp; cd05280
768486000566	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
768486000567	NADP binding site [chemical binding]; other site
768486000568	dimer interface [polypeptide binding]; other site
768486000569	DNA / pantothenate metabolism flavoprotein; Region: DFP; cl04410
768486000570	phosphopantothenoylcysteine decarboxylase; Validated; Region: PRK07313
768486000571	Flavoprotein; Region: Flavoprotein; pfam02441
768486000572	Predicted membrane protein [Function unknown]; Region: COG4684
768486000573	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
768486000574	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
768486000575	NADH(P)-binding; Region: NAD_binding_10; pfam13460
768486000576	NAD(P) binding site [chemical binding]; other site
768486000577	putative active site [active]
768486000578	putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824
768486000579	PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276
768486000580	NAD(P) binding site [chemical binding]; other site
768486000581	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1755
768486000582	fumarate reductase flavoprotein subunit; Validated; Region: PRK06481
768486000583	L-aspartate oxidase; Provisional; Region: PRK06175
768486000584	Enterocin A Immunity; Region: EntA_Immun; pfam08951
768486000585	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
768486000586	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486000587	Coenzyme A binding pocket [chemical binding]; other site
768486000588	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
768486000589	FAD binding domain; Region: FAD_binding_4; pfam01565
768486000590	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
768486000591	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
768486000592	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
768486000593	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
768486000594	active site
768486000595	putative catalytic site [active]
768486000596	DNA binding site [nucleotide binding]
768486000597	putative phosphate binding site [ion binding]; other site
768486000598	metal binding site A [ion binding]; metal-binding site
768486000599	AP binding site [nucleotide binding]; other site
768486000600	metal binding site B [ion binding]; metal-binding site
768486000601	an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130
768486000602	active site
768486000603	catalytic site [active]
768486000604	substrate binding site [chemical binding]; other site
768486000605	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
768486000606	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486000607	Coenzyme A binding pocket [chemical binding]; other site
768486000608	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
768486000609	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
768486000610	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
768486000611	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
768486000612	ligand binding site [chemical binding]; other site
768486000613	active site
768486000614	UGI interface [polypeptide binding]; other site
768486000615	catalytic site [active]
768486000616	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486000617	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
768486000618	active site
768486000619	motif I; other site
768486000620	motif II; other site
768486000621	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
768486000622	Tubby C 2; Region: Tub_2; cl02043
768486000623	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486000624	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
768486000625	Coenzyme A binding pocket [chemical binding]; other site
768486000626	cxxc_20_cxxc protein; Region: cxxc_20_cxxc; TIGR04104
768486000627	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
768486000628	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
768486000629	putative metal binding site [ion binding]; other site
768486000630	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
768486000631	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
768486000632	putative substrate binding pocket [chemical binding]; other site
768486000633	AC domain interface; other site
768486000634	catalytic triad [active]
768486000635	AB domain interface; other site
768486000636	interchain disulfide; other site
768486000637	Predicted membrane protein [Function unknown]; Region: COG3817
768486000638	Protein of unknown function (DUF979); Region: DUF979; pfam06166
768486000639	Protein of unknown function (DUF969); Region: DUF969; pfam06149
768486000640	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
768486000641	arginine-ornithine antiporter; Region: arg_ornith_anti; TIGR03810
768486000642	NrdI Flavodoxin like; Region: Flavodoxin_NdrI; cl17293
768486000643	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
768486000644	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
768486000645	active site turn [active]
768486000646	phosphorylation site [posttranslational modification]
768486000647	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
768486000648	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
768486000649	HPr interaction site; other site
768486000650	glycerol kinase (GK) interaction site [polypeptide binding]; other site
768486000651	active site
768486000652	phosphorylation site [posttranslational modification]
768486000653	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
768486000654	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
768486000655	putative active site [active]
768486000656	Uncharacterized conserved protein [Function unknown]; Region: COG3589
768486000657	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
768486000658	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
768486000659	catalytic core [active]
768486000660	potential frameshift: common BLAST hit: gi|29377198|ref|NP_816352.1| ABC transporter ATP-binding protein
768486000661	potential frameshift: common BLAST hit: gi|389867836|ref|YP_006375259.1| glycerate kinase
768486000662	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
768486000663	Glycerate kinase family; Region: Gly_kinase; cl00841
768486000664	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
768486000665	glutaminase A; Region: Gln_ase; TIGR03814
768486000666	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
768486000667	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
768486000668	Predicted membrane protein [Function unknown]; Region: COG2364
768486000669	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
768486000670	Domain of unknown function (DUF305); Region: DUF305; cl17794
768486000671	Na+/H+ antiporter family; Region: Na_H_antiporter; pfam03553
768486000672	M20 Peptidase Aminoacylase 1-like protein 2-like, amidohydrolase subfamily; Region: M20_ACY1L2_like; cd05672
768486000673	amidohydrolase; Region: amidohydrolases; TIGR01891
768486000674	metal binding site [ion binding]; metal-binding site
768486000675	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
768486000676	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
768486000677	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486000678	dimer interface [polypeptide binding]; other site
768486000679	conserved gate region; other site
768486000680	ABC-ATPase subunit interface; other site
768486000681	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
768486000682	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
768486000683	Walker A/P-loop; other site
768486000684	ATP binding site [chemical binding]; other site
768486000685	Q-loop/lid; other site
768486000686	ABC transporter signature motif; other site
768486000687	Walker B; other site
768486000688	D-loop; other site
768486000689	H-loop/switch region; other site
768486000690	NIL domain; Region: NIL; pfam09383
768486000691	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
768486000692	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486000693	motif II; other site
768486000694	magnesium-transporting ATPase; Provisional; Region: PRK15122
768486000695	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
768486000696	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
768486000697	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
768486000698	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
768486000699	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
768486000700	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
768486000701	active site
768486000702	multimer interface [polypeptide binding]; other site
768486000703	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486000704	non-specific DNA binding site [nucleotide binding]; other site
768486000705	salt bridge; other site
768486000706	sequence-specific DNA binding site [nucleotide binding]; other site
768486000707	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
768486000708	Sulfatase; Region: Sulfatase; pfam00884
768486000709	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
768486000710	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
768486000711	active site
768486000712	metal binding site [ion binding]; metal-binding site
768486000713	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
768486000714	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
768486000715	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
768486000716	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
768486000717	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
768486000718	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
768486000719	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
768486000720	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486000721	dimer interface [polypeptide binding]; other site
768486000722	conserved gate region; other site
768486000723	putative PBP binding loops; other site
768486000724	ABC-ATPase subunit interface; other site
768486000725	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486000726	dimer interface [polypeptide binding]; other site
768486000727	conserved gate region; other site
768486000728	putative PBP binding loops; other site
768486000729	ABC-ATPase subunit interface; other site
768486000730	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
768486000731	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
768486000732	Walker A/P-loop; other site
768486000733	ATP binding site [chemical binding]; other site
768486000734	Q-loop/lid; other site
768486000735	ABC transporter signature motif; other site
768486000736	Walker B; other site
768486000737	D-loop; other site
768486000738	H-loop/switch region; other site
768486000739	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
768486000740	beta-galactosidase; Region: BGL; TIGR03356
768486000741	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
768486000742	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
768486000743	Substrate-binding site [chemical binding]; other site
768486000744	Substrate specificity [chemical binding]; other site
768486000745	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
768486000746	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
768486000747	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
768486000748	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
768486000749	substrate binding site [chemical binding]; other site
768486000750	ATP binding site [chemical binding]; other site
768486000751	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
768486000752	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
768486000753	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
768486000754	catalytic residue [active]
768486000755	probable amidohydrolase EF_0837/AHA_3915; Region: EF_0837; TIGR03583
768486000756	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
768486000757	active site
768486000758	Uncharacterized conserved protein [Function unknown]; Region: COG3589
768486000759	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
768486000760	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
768486000761	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
768486000762	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
768486000763	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
768486000764	DNA-binding site [nucleotide binding]; DNA binding site
768486000765	UTRA domain; Region: UTRA; pfam07702
768486000766	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
768486000767	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
768486000768	beta-galactosidase; Region: BGL; TIGR03356
768486000769	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
768486000770	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
768486000771	active site turn [active]
768486000772	phosphorylation site [posttranslational modification]
768486000773	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
768486000774	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
768486000775	HPr interaction site; other site
768486000776	glycerol kinase (GK) interaction site [polypeptide binding]; other site
768486000777	active site
768486000778	phosphorylation site [posttranslational modification]
768486000779	transcriptional antiterminator BglG; Provisional; Region: PRK09772
768486000780	CAT RNA binding domain; Region: CAT_RBD; smart01061
768486000781	PRD domain; Region: PRD; pfam00874
768486000782	PRD domain; Region: PRD; pfam00874
768486000783	Sortase A (SrtA) or subfamily-1 sortases are cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the...; Region: Sortase_A_1; cd06165
768486000784	active site
768486000785	catalytic site [active]
768486000786	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs; Region: NTP-PPase_RS21-C6_like; cd11537
768486000787	homodimer interface [polypeptide binding]; other site
768486000788	chemical substrate binding site [chemical binding]; other site
768486000789	oligomer interface [polypeptide binding]; other site
768486000790	metal binding site [ion binding]; metal-binding site
768486000791	benzoate transport; Region: 2A0115; TIGR00895
768486000792	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486000793	putative substrate translocation pore; other site
768486000794	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
768486000795	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
768486000796	putative active site cavity [active]
768486000797	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
768486000798	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
768486000799	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
768486000800	metal ion-dependent adhesion site (MIDAS); other site
768486000801	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
768486000802	domain interaction interfaces [polypeptide binding]; other site
768486000803	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
768486000804	HTH domain; Region: HTH_11; pfam08279
768486000805	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cd00133
768486000806	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
768486000807	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
768486000808	Walker A/P-loop; other site
768486000809	ATP binding site [chemical binding]; other site
768486000810	Q-loop/lid; other site
768486000811	ABC transporter signature motif; other site
768486000812	Walker B; other site
768486000813	D-loop; other site
768486000814	H-loop/switch region; other site
768486000815	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
768486000816	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
768486000817	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
768486000818	Walker A/P-loop; other site
768486000819	ATP binding site [chemical binding]; other site
768486000820	Q-loop/lid; other site
768486000821	ABC transporter signature motif; other site
768486000822	Walker B; other site
768486000823	D-loop; other site
768486000824	H-loop/switch region; other site
768486000825	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
768486000826	DNA binding residues [nucleotide binding]
768486000827	agmatine deiminase; Provisional; Region: PRK13551
768486000828	agmatine deiminase; Region: agmatine_aguA; TIGR03380
768486000829	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
768486000830	putrescine carbamoyltransferase; Provisional; Region: PRK02255
768486000831	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
768486000832	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
768486000833	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
768486000834	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
768486000835	DNA binding residues [nucleotide binding]
768486000836	dimerization interface [polypeptide binding]; other site
768486000837	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
768486000838	active pocket/dimerization site; other site
768486000839	active site
768486000840	phosphorylation site [posttranslational modification]
768486000841	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
768486000842	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
768486000843	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
768486000844	active site
768486000845	phosphorylation site [posttranslational modification]
768486000846	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
768486000847	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
768486000848	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
768486000849	tagatose-6-phosphate kinase; Region: lacC; TIGR01231
768486000850	putative substrate binding site [chemical binding]; other site
768486000851	putative ATP binding site [chemical binding]; other site
768486000852	potential frameshift: common BLAST hit: gi|29376351|ref|NP_815505.1| tagatose 1,6-diphosphate aldolase
768486000853	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
768486000854	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
768486000855	dimer interface [polypeptide binding]; other site
768486000856	active site
768486000857	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
768486000858	putative active site [active]
768486000859	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
768486000860	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
768486000861	DNA-binding site [nucleotide binding]; DNA binding site
768486000862	UTRA domain; Region: UTRA; pfam07702
768486000863	potential frameshift: common BLAST hit: gi|220930091|ref|YP_002507000.1| SMC domain-containing protein
768486000864	sporadically distributed protein, TIGR04141 family; Region: TIGR04141
768486000865	AAA domain; Region: AAA_11; pfam13086
768486000866	Part of AAA domain; Region: AAA_19; pfam13245
768486000867	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
768486000868	AAA domain; Region: AAA_12; pfam13087
768486000869	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
768486000870	potential frameshift: common BLAST hit: gi|194450167|ref|YP_002045460.1| helicase c2
768486000871	Abortive infection C-terminus; Region: Abi_C; pfam14355
768486000872	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
768486000873	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
768486000874	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486000875	non-specific DNA binding site [nucleotide binding]; other site
768486000876	salt bridge; other site
768486000877	sequence-specific DNA binding site [nucleotide binding]; other site
768486000878	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486000879	non-specific DNA binding site [nucleotide binding]; other site
768486000880	salt bridge; other site
768486000881	sequence-specific DNA binding site [nucleotide binding]; other site
768486000882	CHC2 zinc finger; Region: zf-CHC2; cl17510
768486000883	Helix-turn-helix domain; Region: HTH_17; pfam12728
768486000884	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486000885	non-specific DNA binding site [nucleotide binding]; other site
768486000886	salt bridge; other site
768486000887	sequence-specific DNA binding site [nucleotide binding]; other site
768486000888	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
768486000889	Int/Topo IB signature motif; other site
768486000890	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
768486000891	FeS assembly protein SufB; Region: sufB; TIGR01980
768486000892	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
768486000893	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
768486000894	trimerization site [polypeptide binding]; other site
768486000895	active site
768486000896	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
768486000897	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
768486000898	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
768486000899	catalytic residue [active]
768486000900	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
768486000901	FeS assembly protein SufD; Region: sufD; TIGR01981
768486000902	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
768486000903	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
768486000904	Walker A/P-loop; other site
768486000905	ATP binding site [chemical binding]; other site
768486000906	Q-loop/lid; other site
768486000907	ABC transporter signature motif; other site
768486000908	Walker B; other site
768486000909	D-loop; other site
768486000910	H-loop/switch region; other site
768486000911	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
768486000912	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
768486000913	potential frameshift: common BLAST hit: gi|389867756|ref|YP_006375179.1| metal ion ABC superfamily ATP binding cassette transporter
768486000914	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486000915	ABC-ATPase subunit interface; other site
768486000916	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
768486000917	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
768486000918	Walker A/P-loop; other site
768486000919	ATP binding site [chemical binding]; other site
768486000920	Q-loop/lid; other site
768486000921	ABC transporter signature motif; other site
768486000922	Walker B; other site
768486000923	D-loop; other site
768486000924	H-loop/switch region; other site
768486000925	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
768486000926	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
768486000927	lipoyl attachment site [posttranslational modification]; other site
768486000928	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
768486000929	ArsC family; Region: ArsC; pfam03960
768486000930	putative ArsC-like catalytic residues; other site
768486000931	putative TRX-like catalytic residues [active]
768486000932	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
768486000933	Transcriptional regulator [Transcription]; Region: LysR; COG0583
768486000934	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
768486000935	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
768486000936	dimerization interface [polypeptide binding]; other site
768486000937	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
768486000938	C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT_C4-dicarb_trans; cd09325
768486000939	gating phenylalanine in ion channel; other site
768486000940	Predicted membrane protein [Function unknown]; Region: COG2855
768486000941	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
768486000942	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
768486000943	DNA binding site [nucleotide binding]
768486000944	active site
768486000945	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
768486000946	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
768486000947	Ligand binding site; other site
768486000948	Putative Catalytic site; other site
768486000949	DXD motif; other site
768486000950	Mga helix-turn-helix domain; Region: Mga; pfam05043
768486000951	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
768486000952	active site
768486000953	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
768486000954	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
768486000955	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
768486000956	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
768486000957	dimer interface [polypeptide binding]; other site
768486000958	active site
768486000959	glycine-pyridoxal phosphate binding site [chemical binding]; other site
768486000960	folate binding site [chemical binding]; other site
768486000961	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
768486000962	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
768486000963	protein-(glutamine-N5) methyltransferase, release factor-specific; Region: RF_mod_PrmC; TIGR03534
768486000964	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486000965	S-adenosylmethionine binding site [chemical binding]; other site
768486000966	peptide chain release factor 1; Validated; Region: prfA; PRK00591
768486000967	This domain is found in peptide chain release factors; Region: PCRF; smart00937
768486000968	RF-1 domain; Region: RF-1; pfam00472
768486000969	thymidine kinase; Provisional; Region: PRK04296
768486000970	Methyltransferase domain; Region: Methyltransf_23; pfam13489
768486000971	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486000972	S-adenosylmethionine binding site [chemical binding]; other site
768486000973	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
768486000974	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
768486000975	Catalytic site [active]
768486000976	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
768486000977	Uncharacterized BCR, COG1636; Region: DUF208; pfam02677
768486000978	potential frameshift: common BLAST hit: gi|29377045|ref|NP_816199.1| cation transporter
768486000979	CAAX protease self-immunity; Region: Abi; pfam02517
768486000980	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486000981	non-specific DNA binding site [nucleotide binding]; other site
768486000982	salt bridge; other site
768486000983	sequence-specific DNA binding site [nucleotide binding]; other site
768486000984	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
768486000985	UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769
768486000986	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
768486000987	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
768486000988	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
768486000989	catalytic triad [active]
768486000990	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
768486000991	Bacteriophage peptidoglycan hydrolase; Region: Amidase_5; pfam05382
768486000992	AAA-like domain; Region: AAA_10; pfam12846
768486000993	PrgI family protein; Region: PrgI; pfam12666
768486000994	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
768486000995	Cna protein B-type domain; Region: Cna_B; pfam05738
768486000996	Cna protein B-type domain; Region: Cna_B; pfam05738
768486000997	Cna protein B-type domain; Region: Cna_B; pfam05738
768486000998	Cna protein B-type domain; Region: Cna_B; pfam05738
768486000999	2-hydroxycarboxylate transporter family; Region: 2HCT; cl01386
768486001000	Sugar transport protein; Region: Sugar_transport; pfam06800
768486001001	D-ribose pyranase; Provisional; Region: PRK11797
768486001002	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
768486001003	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
768486001004	substrate binding site [chemical binding]; other site
768486001005	dimer interface [polypeptide binding]; other site
768486001006	ATP binding site [chemical binding]; other site
768486001007	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
768486001008	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
768486001009	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
768486001010	Beta-lactamase; Region: Beta-lactamase; pfam00144
768486001011	Predicted ring-cleavage extradiol dioxygenase [General function prediction only]; Region: COG2514
768486001012	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
768486001013	active site
768486001014	metal binding site [ion binding]; metal-binding site
768486001015	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
768486001016	active site
768486001017	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
768486001018	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
768486001019	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
768486001020	Walker A/P-loop; other site
768486001021	ATP binding site [chemical binding]; other site
768486001022	Q-loop/lid; other site
768486001023	ABC transporter signature motif; other site
768486001024	Walker B; other site
768486001025	D-loop; other site
768486001026	H-loop/switch region; other site
768486001027	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
768486001028	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
768486001029	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486001030	Walker A/P-loop; other site
768486001031	ATP binding site [chemical binding]; other site
768486001032	Q-loop/lid; other site
768486001033	ABC transporter signature motif; other site
768486001034	Walker B; other site
768486001035	D-loop; other site
768486001036	H-loop/switch region; other site
768486001037	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
768486001038	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
768486001039	Acyl carrier protein phosphodiesterase [Lipid metabolism]; Region: AcpD; COG1182
768486001040	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
768486001041	Domain of unknown function DUF20; Region: UPF0118; pfam01594
768486001042	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; cl01516
768486001043	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
768486001044	Sulfatase; Region: Sulfatase; pfam00884
768486001045	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
768486001046	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
768486001047	homodimer interface [polypeptide binding]; other site
768486001048	NAD binding pocket [chemical binding]; other site
768486001049	ATP binding pocket [chemical binding]; other site
768486001050	Mg binding site [ion binding]; other site
768486001051	active-site loop [active]
768486001052	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
768486001053	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
768486001054	active site
768486001055	Domain of unknown function (DUF1827); Region: DUF1827; pfam08860
768486001056	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
768486001057	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
768486001058	DNA binding residues [nucleotide binding]
768486001059	dimer interface [polypeptide binding]; other site
768486001060	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
768486001061	potential frameshift: common BLAST hit: gi|389869533|ref|YP_006376956.1| LacI family transcriptional regulator
768486001062	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
768486001063	Transcriptional regulators [Transcription]; Region: PurR; COG1609
768486001064	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
768486001065	DNA binding site [nucleotide binding]
768486001066	domain linker motif; other site
768486001067	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
768486001068	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
768486001069	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
768486001070	ring oligomerisation interface [polypeptide binding]; other site
768486001071	ATP/Mg binding site [chemical binding]; other site
768486001072	stacking interactions; other site
768486001073	hinge regions; other site
768486001074	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
768486001075	oligomerisation interface [polypeptide binding]; other site
768486001076	mobile loop; other site
768486001077	roof hairpin; other site
768486001078	CAAX protease self-immunity; Region: Abi; pfam02517
768486001079	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
768486001080	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
768486001081	YycH protein; Region: YycI; pfam09648
768486001082	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4863
768486001083	YycH protein; Region: YycH; pfam07435
768486001084	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
768486001085	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
768486001086	dimerization interface [polypeptide binding]; other site
768486001087	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
768486001088	putative active site [active]
768486001089	heme pocket [chemical binding]; other site
768486001090	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
768486001091	dimer interface [polypeptide binding]; other site
768486001092	phosphorylation site [posttranslational modification]
768486001093	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
768486001094	ATP binding site [chemical binding]; other site
768486001095	Mg2+ binding site [ion binding]; other site
768486001096	G-X-G motif; other site
768486001097	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
768486001098	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486001099	active site
768486001100	phosphorylation site [posttranslational modification]
768486001101	intermolecular recognition site; other site
768486001102	dimerization interface [polypeptide binding]; other site
768486001103	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
768486001104	DNA binding site [nucleotide binding]
768486001105	Domain of unknown function (DUF1836); Region: DUF1836; pfam08876
768486001106	EDD domain protein, DegV family; Region: DegV; TIGR00762
768486001107	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
768486001108	Tocopherol cyclase; Region: Tocopherol_cycl; cl14571
768486001109	Uncharacterized ACR, COG2135; Region: DUF159; pfam02586
768486001110	potential frameshift: common BLAST hit: gi|29377126|ref|NP_816280.1| glycine betaine/L-proline ABC transporter glycine
768486001111	ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]; Region: ProV; COG4175
768486001112	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
768486001113	Walker A/P-loop; other site
768486001114	ATP binding site [chemical binding]; other site
768486001115	Q-loop/lid; other site
768486001116	ABC transporter signature motif; other site
768486001117	Walker B; other site
768486001118	D-loop; other site
768486001119	H-loop/switch region; other site
768486001120	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
768486001121	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
768486001122	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
768486001123	DNA-binding site [nucleotide binding]; DNA binding site
768486001124	Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels [Inorganic ion transport and metabolism]; Region: COG0490
768486001125	TrkA-C domain; Region: TrkA_C; pfam02080
768486001126	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
768486001127	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
768486001128	G1 box; other site
768486001129	GTP/Mg2+ binding site [chemical binding]; other site
768486001130	Switch I region; other site
768486001131	G2 box; other site
768486001132	G3 box; other site
768486001133	Switch II region; other site
768486001134	G4 box; other site
768486001135	G5 box; other site
768486001136	Nucleoside recognition; Region: Gate; pfam07670
768486001137	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
768486001138	Nucleoside recognition; Region: Gate; pfam07670
768486001139	This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria; Region: FeoA; smart00899
768486001140	FeoA domain; Region: FeoA; pfam04023
768486001141	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
768486001142	catalytic residues [active]
768486001143	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07306
768486001144	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
768486001145	Class I ribonucleotide reductase; Region: RNR_I; cd01679
768486001146	active site
768486001147	dimer interface [polypeptide binding]; other site
768486001148	catalytic residues [active]
768486001149	effector binding site; other site
768486001150	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
768486001151	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
768486001152	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
768486001153	dimer interface [polypeptide binding]; other site
768486001154	putative radical transfer pathway; other site
768486001155	diiron center [ion binding]; other site
768486001156	tyrosyl radical; other site
768486001157	hypothetical protein; Provisional; Region: PRK02947
768486001158	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
768486001159	putative active site [active]
768486001160	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
768486001161	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
768486001162	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
768486001163	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
768486001164	active pocket/dimerization site; other site
768486001165	active site
768486001166	phosphorylation site [posttranslational modification]
768486001167	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
768486001168	active site
768486001169	phosphorylation site [posttranslational modification]
768486001170	Alpha-L-fucosidase; Region: Alpha_L_fucos; pfam01120
768486001171	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
768486001172	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
768486001173	nucleotide binding site [chemical binding]; other site
768486001174	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
768486001175	L-fucose isomerase; Provisional; Region: fucI; PRK10991
768486001176	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
768486001177	hexamer (dimer of trimers) interface [polypeptide binding]; other site
768486001178	trimer interface [polypeptide binding]; other site
768486001179	substrate binding site [chemical binding]; other site
768486001180	Mn binding site [ion binding]; other site
768486001181	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
768486001182	intersubunit interface [polypeptide binding]; other site
768486001183	active site
768486001184	Zn2+ binding site [ion binding]; other site
768486001185	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
768486001186	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
768486001187	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
768486001188	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
768486001189	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
768486001190	substrate binding site [chemical binding]; other site
768486001191	hexamer interface [polypeptide binding]; other site
768486001192	metal binding site [ion binding]; metal-binding site
768486001193	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
768486001194	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
768486001195	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
768486001196	active site
768486001197	P-loop; other site
768486001198	phosphorylation site [posttranslational modification]
768486001199	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
768486001200	active site
768486001201	phosphorylation site [posttranslational modification]
768486001202	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
768486001203	active site
768486001204	P-loop; other site
768486001205	phosphorylation site [posttranslational modification]
768486001206	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
768486001207	active site
768486001208	phosphorylation site [posttranslational modification]
768486001209	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
768486001210	HTH domain; Region: HTH_11; pfam08279
768486001211	PRD domain; Region: PRD; pfam00874
768486001212	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
768486001213	active site
768486001214	P-loop; other site
768486001215	phosphorylation site [posttranslational modification]
768486001216	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
768486001217	Domain of unknown function DUF20; Region: UPF0118; pfam01594
768486001218	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
768486001219	MgtC family; Region: MgtC; pfam02308
768486001220	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
768486001221	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
768486001222	active site
768486001223	trimer interface [polypeptide binding]; other site
768486001224	allosteric site; other site
768486001225	active site lid [active]
768486001226	hexamer (dimer of trimers) interface [polypeptide binding]; other site
768486001227	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
768486001228	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486001229	Walker A/P-loop; other site
768486001230	ATP binding site [chemical binding]; other site
768486001231	Q-loop/lid; other site
768486001232	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
768486001233	ABC transporter signature motif; other site
768486001234	Walker B; other site
768486001235	D-loop; other site
768486001236	ABC transporter; Region: ABC_tran_2; pfam12848
768486001237	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
768486001238	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
768486001239	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486001240	putative substrate translocation pore; other site
768486001241	Uncharacterized conserved protein [Function unknown]; Region: COG0398
768486001242	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
768486001243	Quinolinate synthetase A protein; Region: NadA; cl00420
768486001244	Abi-like protein; Region: Abi_2; pfam07751
768486001245	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
768486001246	Phage holin; Region: Phage_holin_5; pfam06946
768486001247	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
768486001248	active site
768486001249	catalytic triad [active]
768486001250	oxyanion hole [active]
768486001251	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
768486001252	Phage tail protein; Region: Sipho_tail; cl17486
768486001253	tape measure domain; Region: tape_meas_nterm; TIGR02675
768486001254	Bacteriophage Gp15 protein; Region: Phage_Gp15; pfam06854
768486001255	Minor capsid protein from bacteriophage; Region: Minor_capsid_3; pfam12691
768486001256	Minor capsid protein; Region: Minor_capsid_2; pfam11114
768486001257	Minor capsid protein; Region: Minor_capsid_1; pfam10665
768486001258	Head-Tail Connector Proteins gp6 and gp15, and similar proteins; Region: gp6_gp15_like; cl12049
768486001259	HeH/LEM domain; Region: HeH; pfam12949
768486001260	Phage minor structural protein GP20; Region: Phage_GP20; pfam06810
768486001261	Phage minor capsid protein 2; Region: Phage_min_cap2; pfam06152
768486001262	phage portal protein, putative, A118 family; Region: A118_put_portal; TIGR01542
768486001263	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
768486001264	potential frameshift: common BLAST hit: gi|258508120|ref|YP_003170871.1| phage-related terminase large subunit
768486001265	Uncharacterized conserved protein [Function unknown]; Region: COG5484
768486001266	Homeodomain-like domain; Region: HTH_23; pfam13384
768486001267	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
768486001268	DNA binding residues [nucleotide binding]
768486001269	Protein of unknown function (DUF1642); Region: DUF1642; pfam07852
768486001270	YopX protein; Region: YopX; pfam09643
768486001271	Protein of unknown function (DUF1064); Region: DUF1064; pfam06356
768486001272	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
768486001273	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486001274	Walker A motif; other site
768486001275	ATP binding site [chemical binding]; other site
768486001276	Walker B motif; other site
768486001277	Helix-turn-helix domain; Region: HTH_36; pfam13730
768486001278	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
768486001279	potential frameshift: common BLAST hit: gi|28211758|ref|NP_782702.1| recT protein
768486001280	YqaJ-like viral recombinase domain; Region: YqaJ; cl09232
768486001281	YqaJ-like viral recombinase domain; Region: YqaJ; cl09232
768486001282	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
768486001283	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486001284	salt bridge; other site
768486001285	non-specific DNA binding site [nucleotide binding]; other site
768486001286	sequence-specific DNA binding site [nucleotide binding]; other site
768486001287	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486001288	non-specific DNA binding site [nucleotide binding]; other site
768486001289	salt bridge; other site
768486001290	sequence-specific DNA binding site [nucleotide binding]; other site
768486001291	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
768486001292	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486001293	non-specific DNA binding site [nucleotide binding]; other site
768486001294	salt bridge; other site
768486001295	sequence-specific DNA binding site [nucleotide binding]; other site
768486001296	Predicted transcriptional regulator [Transcription]; Region: COG2932
768486001297	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
768486001298	Catalytic site [active]
768486001299	Plasmid stabilisation system protein; Region: Plasmid_stabil; cl17483
768486001300	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
768486001301	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
768486001302	Int/Topo IB signature motif; other site
768486001303	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
768486001304	core dimer interface [polypeptide binding]; other site
768486001305	peripheral dimer interface [polypeptide binding]; other site
768486001306	L10 interface [polypeptide binding]; other site
768486001307	L11 interface [polypeptide binding]; other site
768486001308	putative EF-Tu interaction site [polypeptide binding]; other site
768486001309	putative EF-G interaction site [polypeptide binding]; other site
768486001310	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
768486001311	23S rRNA interface [nucleotide binding]; other site
768486001312	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
768486001313	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
768486001314	mRNA/rRNA interface [nucleotide binding]; other site
768486001315	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
768486001316	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
768486001317	23S rRNA interface [nucleotide binding]; other site
768486001318	L7/L12 interface [polypeptide binding]; other site
768486001319	putative thiostrepton binding site; other site
768486001320	L25 interface [polypeptide binding]; other site
768486001321	L-serine dehydratase, iron-sulfur-dependent, beta subunit; Region: sda_beta; TIGR00719
768486001322	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
768486001323	C-terminal ACT domain of the L-serine dehydratase (LSD), iron-sulfur-dependent, beta subunit; Region: ACT_LSD; cd04903
768486001324	putative L-serine binding site [chemical binding]; other site
768486001325	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
768486001326	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
768486001327	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
768486001328	PGAP1-like protein; Region: PGAP1; pfam07819
768486001329	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
768486001330	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
768486001331	putative homodimer interface [polypeptide binding]; other site
768486001332	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
768486001333	heterodimer interface [polypeptide binding]; other site
768486001334	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
768486001335	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
768486001336	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
768486001337	QueT transporter; Region: QueT; pfam06177
768486001338	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
768486001339	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
768486001340	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
768486001341	AAA domain; Region: AAA_30; pfam13604
768486001342	Family description; Region: UvrD_C_2; pfam13538
768486001343	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
768486001344	catalytic core [active]
768486001345	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
768486001346	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
768486001347	Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  DHPS, a...; Region: Pterin_binding; cl00219
768486001348	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486001349	S-adenosylmethionine binding site [chemical binding]; other site
768486001350	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
768486001351	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
768486001352	MgtE intracellular N domain; Region: MgtE_N; pfam03448
768486001353	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
768486001354	Divalent cation transporter; Region: MgtE; pfam01769
768486001355	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
768486001356	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
768486001357	active site
768486001358	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK04885
768486001359	ATP-NAD kinase; Region: NAD_kinase; pfam01513
768486001360	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
768486001361	synthetase active site [active]
768486001362	NTP binding site [chemical binding]; other site
768486001363	metal binding site [ion binding]; metal-binding site
768486001364	Uncharacterized subgroup 1 of the CYTH-like superfamily; Region: CYTH-like_Pase_1; cd07762
768486001365	putative active site [active]
768486001366	putative metal binding residues [ion binding]; other site
768486001367	signature motif; other site
768486001368	putative triphosphate binding site [ion binding]; other site
768486001369	Thioredoxin; Region: Thioredoxin_5; pfam13743
768486001370	intracellular protease, PfpI family; Region: PfpI; TIGR01382
768486001371	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
768486001372	proposed catalytic triad [active]
768486001373	conserved cys residue [active]
768486001374	prephenate dehydratase; Provisional; Region: PRK11898
768486001375	Prephenate dehydratase; Region: PDT; pfam00800
768486001376	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
768486001377	putative L-Phe binding site [chemical binding]; other site
768486001378	shikimate kinase; Reviewed; Region: aroK; PRK00131
768486001379	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
768486001380	ADP binding site [chemical binding]; other site
768486001381	magnesium binding site [ion binding]; other site
768486001382	putative shikimate binding site; other site
768486001383	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
768486001384	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
768486001385	hinge; other site
768486001386	active site
768486001387	potential frameshift: common BLAST hit: gi|389868773|ref|YP_006376196.1| prephenate dehydrogenase
768486001388	prephenate dehydrogenase; Validated; Region: PRK06545
768486001389	prephenate dehydrogenase; Validated; Region: PRK08507
768486001390	C-terminal ACT domain of the monofunctional, NAD dependent, prephenate dehydrogenase (PDH); Region: ACT_PDH-BS; cd04909
768486001391	prephenate dehydrogenase; Validated; Region: PRK08507
768486001392	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
768486001393	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
768486001394	Tetramer interface [polypeptide binding]; other site
768486001395	active site
768486001396	FMN-binding site [chemical binding]; other site
768486001397	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
768486001398	active site
768486001399	dimer interface [polypeptide binding]; other site
768486001400	metal binding site [ion binding]; metal-binding site
768486001401	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
768486001402	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
768486001403	Uncharacterized conserved protein [Function unknown]; Region: COG2461
768486001404	Family of unknown function (DUF438); Region: DUF438; pfam04282
768486001405	Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814
768486001406	Domain of unknown function (DUF1858); Region: DUF1858; pfam08984
768486001407	potential frameshift: common BLAST hit: gi|190606548|ref|YP_001974833.1| putative DNA-directed DNA polymerase
768486001408	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
768486001409	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486001410	putative substrate translocation pore; other site
768486001411	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
768486001412	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
768486001413	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486001414	putative substrate translocation pore; other site
768486001415	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
768486001416	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
768486001417	Helix-turn-helix domain; Region: HTH_18; pfam12833
768486001418	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
768486001419	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
768486001420	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
768486001421	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
768486001422	PemK-like protein; Region: PemK; pfam02452
768486001423	aromatic amino acid aminotransferase; Validated; Region: PRK07309
768486001424	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
768486001425	pyridoxal 5'-phosphate binding site [chemical binding]; other site
768486001426	homodimer interface [polypeptide binding]; other site
768486001427	catalytic residue [active]
768486001428	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
768486001429	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
768486001430	metal binding site [ion binding]; metal-binding site
768486001431	dimer interface [polypeptide binding]; other site
768486001432	aspartate kinase; Reviewed; Region: PRK09034
768486001433	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
768486001434	nucleotide binding site [chemical binding]; other site
768486001435	substrate binding site [chemical binding]; other site
768486001436	ACT domains located C-terminal to the catalytic domain of the lysine plus threonine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-YclM-BS_1; cd04911
768486001437	allosteric regulatory residue; other site
768486001438	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
768486001439	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
768486001440	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
768486001441	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
768486001442	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
768486001443	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
768486001444	putative trimer interface [polypeptide binding]; other site
768486001445	putative CoA binding site [chemical binding]; other site
768486001446	potential frameshift: common BLAST hit: gi|389867662|ref|YP_006375085.1| dihydrodipicolinate reductase
768486001447	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
768486001448	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
768486001449	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
768486001450	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
768486001451	dihydrodipicolinate synthase; Region: dapA; TIGR00674
768486001452	dimer interface [polypeptide binding]; other site
768486001453	active site
768486001454	catalytic residue [active]
768486001455	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
768486001456	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
768486001457	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
768486001458	diaminopimelate decarboxylase; Region: lysA; TIGR01048
768486001459	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
768486001460	active site
768486001461	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
768486001462	substrate binding site [chemical binding]; other site
768486001463	catalytic residues [active]
768486001464	dimer interface [polypeptide binding]; other site
768486001465	Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272
768486001466	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
768486001467	potential frameshift: common BLAST hit: gi|389868574|ref|YP_006375997.1| sortase
768486001468	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
768486001469	catalytic site [active]
768486001470	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
768486001471	active site
768486001472	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
768486001473	Cna protein B-type domain; Region: Cna_B; pfam05738
768486001474	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
768486001475	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
768486001476	Cna protein B-type domain; Region: Cna_B; pfam05738
768486001477	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
768486001478	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
768486001479	metal ion-dependent adhesion site (MIDAS); other site
768486001480	Repeat unit of collagen-binding protein domain B; Region: CollagenBindB; cd00222
768486001481	domain interaction interfaces [polypeptide binding]; other site
768486001482	Cna protein B-type domain; Region: Cna_B; pfam05738
768486001483	Cna protein B-type domain; Region: Cna_B; pfam05738
768486001484	Mga helix-turn-helix domain; Region: Mga; pfam05043
768486001485	elongation factor P; Validated; Region: PRK00529
768486001486	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
768486001487	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
768486001488	RNA binding site [nucleotide binding]; other site
768486001489	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
768486001490	RNA binding site [nucleotide binding]; other site
768486001491	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
768486001492	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
768486001493	dimer interface [polypeptide binding]; other site
768486001494	pyridoxal 5'-phosphate binding site [chemical binding]; other site
768486001495	catalytic residue [active]
768486001496	cystathionine gamma-synthase/cystathionine beta-lyase; Validated; Region: PRK06176
768486001497	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
768486001498	homodimer interface [polypeptide binding]; other site
768486001499	substrate-cofactor binding pocket; other site
768486001500	pyridoxal 5'-phosphate binding site [chemical binding]; other site
768486001501	catalytic residue [active]
768486001502	S-ribosylhomocysteinase; Provisional; Region: PRK02260
768486001503	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
768486001504	catalytic residues [active]
768486001505	dimer interface [polypeptide binding]; other site
768486001506	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
768486001507	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
768486001508	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
768486001509	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
768486001510	ArsC family; Region: ArsC; pfam03960
768486001511	putative catalytic residues [active]
768486001512	thiol/disulfide switch; other site
768486001513	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
768486001514	ArsC family; Region: ArsC; pfam03960
768486001515	putative catalytic residues [active]
768486001516	thiol/disulfide switch; other site
768486001517	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
768486001518	Part of AAA domain; Region: AAA_19; pfam13245
768486001519	Family description; Region: UvrD_C_2; pfam13538
768486001520	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
768486001521	DNA polymerase type-B family catalytic domain. DNA-directed DNA polymerases elongate DNA by adding nucleotide triphosphate (dNTP) residues to the 5'-end of the growing chain of DNA. DNA-directed DNA polymerases are multifunctional with both...; Region: POLBc; cl10023
768486001522	Accessory gene regulator B; Region: AgrB; pfam04647
768486001523	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
768486001524	potential frameshift: common BLAST hit: gi|389867643|ref|YP_006375066.1| accessory gene regulator protein A
768486001525	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
768486001526	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486001527	active site
768486001528	phosphorylation site [posttranslational modification]
768486001529	intermolecular recognition site; other site
768486001530	dimerization interface [polypeptide binding]; other site
768486001531	LytTr DNA-binding domain; Region: LytTR; cl04498
768486001532	LytTr DNA-binding domain; Region: LytTR; pfam04397
768486001533	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
768486001534	Metal binding protein AcdA.  These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AcdA proteins belong to the TroA superfamily of helical backbone metal receptor...; Region: AdcA; cd01017
768486001535	metal binding site [ion binding]; metal-binding site
768486001536	YodA lipocalin-like domain; Region: YodA; pfam09223
768486001537	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
768486001538	Domain of unknown function DUF20; Region: UPF0118; pfam01594
768486001539	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
768486001540	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486001541	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486001542	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
768486001543	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486001544	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486001545	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486001546	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
768486001547	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486001548	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486001549	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486001550	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486001551	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
768486001552	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
768486001553	Ca binding site [ion binding]; other site
768486001554	active site
768486001555	catalytic site [active]
768486001556	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
768486001557	FtsX-like permease family; Region: FtsX; pfam02687
768486001558	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
768486001559	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
768486001560	FtsX-like permease family; Region: FtsX; pfam02687
768486001561	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
768486001562	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
768486001563	Walker A/P-loop; other site
768486001564	ATP binding site [chemical binding]; other site
768486001565	Q-loop/lid; other site
768486001566	ABC transporter signature motif; other site
768486001567	Walker B; other site
768486001568	D-loop; other site
768486001569	H-loop/switch region; other site
768486001570	Isochorismatase family; Region: Isochorismatase; pfam00857
768486001571	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
768486001572	catalytic triad [active]
768486001573	conserved cis-peptide bond; other site
768486001574	potential frameshift: common BLAST hit: gi|29377426|ref|NP_816580.1| LacI family sugar-binding transcriptional regulator
768486001575	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
768486001576	NlpC/P60 family; Region: NLPC_P60; pfam00877
768486001577	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
768486001578	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
768486001579	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
768486001580	Walker A/P-loop; other site
768486001581	ATP binding site [chemical binding]; other site
768486001582	Q-loop/lid; other site
768486001583	ABC transporter signature motif; other site
768486001584	Walker B; other site
768486001585	D-loop; other site
768486001586	H-loop/switch region; other site
768486001587	Protein of unknown function (DUF1093); Region: DUF1093; pfam06486
768486001588	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
768486001589	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_2; cd03402
768486001590	Domain of unknown function (DUF4097); Region: DUF4097; pfam13349
768486001591	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
768486001592	Protein of unknown function (DUF1700); Region: DUF1700; pfam08006
768486001593	Predicted transcriptional regulators [Transcription]; Region: COG1695
768486001594	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
768486001595	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
768486001596	TRAM1-like protein; Region: TRAM1; pfam08390
768486001597	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
768486001598	dimerization interface [polypeptide binding]; other site
768486001599	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
768486001600	dimer interface [polypeptide binding]; other site
768486001601	phosphorylation site [posttranslational modification]
768486001602	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
768486001603	ATP binding site [chemical binding]; other site
768486001604	Mg2+ binding site [ion binding]; other site
768486001605	G-X-G motif; other site
768486001606	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
768486001607	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486001608	active site
768486001609	phosphorylation site [posttranslational modification]
768486001610	intermolecular recognition site; other site
768486001611	dimerization interface [polypeptide binding]; other site
768486001612	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
768486001613	DNA binding site [nucleotide binding]
768486001614	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
768486001615	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
768486001616	Walker A/P-loop; other site
768486001617	ATP binding site [chemical binding]; other site
768486001618	Q-loop/lid; other site
768486001619	ABC transporter signature motif; other site
768486001620	Walker B; other site
768486001621	D-loop; other site
768486001622	H-loop/switch region; other site
768486001623	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
768486001624	FtsX-like permease family; Region: FtsX; pfam02687
768486001625	RNA polymerase sigma-70 factor, TIGR02954 family; Region: Sig70_famx3
768486001626	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
768486001627	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
768486001628	DNA binding residues [nucleotide binding]
768486001629	Domain of unknown function (DUF1905); Region: DUF1905; pfam08922
768486001630	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486001631	Major Facilitator Superfamily; Region: MFS_1; pfam07690
768486001632	putative substrate translocation pore; other site
768486001633	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486001634	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
768486001635	DNA binding residues [nucleotide binding]
768486001636	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
768486001637	putative dimer interface [polypeptide binding]; other site
768486001638	Predicted transcriptional regulators [Transcription]; Region: COG1695
768486001639	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
768486001640	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
768486001641	Phenolic acid decarboxylase (PAD); Region: PA_decarbox; cl01382
768486001642	UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Region: Arch_glmU; TIGR03992
768486001643	Streptococcus agalactiae RgfB, part of a putative two component signal transduction system, and related proteins; Region: RgfB-like; cd09079
768486001644	putative catalytic site [active]
768486001645	putative metal binding site [ion binding]; other site
768486001646	putative phosphate binding site [ion binding]; other site
768486001647	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
768486001648	PTS system, IIBC component; Region: PTS-II-BC-unk1; TIGR02003
768486001649	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
768486001650	active site turn [active]
768486001651	phosphorylation site [posttranslational modification]
768486001652	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
768486001653	HPr interaction site; other site
768486001654	glycerol kinase (GK) interaction site [polypeptide binding]; other site
768486001655	active site
768486001656	phosphorylation site [posttranslational modification]
768486001657	maltose phosphorylase; Provisional; Region: PRK13807
768486001658	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
768486001659	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
768486001660	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
768486001661	beta-phosphoglucomutase; Region: bPGM; TIGR01990
768486001662	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486001663	motif II; other site
768486001664	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
768486001665	active site
768486001666	catalytic residues [active]
768486001667	Transcriptional regulators [Transcription]; Region: PurR; COG1609
768486001668	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
768486001669	DNA binding site [nucleotide binding]
768486001670	domain linker motif; other site
768486001671	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
768486001672	putative dimerization interface [polypeptide binding]; other site
768486001673	putative ligand binding site [chemical binding]; other site
768486001674	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
768486001675	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
768486001676	tyrosine decarboxylase, Enterococcus type; Region: tyr_de_CO2_Ent; TIGR03811
768486001677	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
768486001678	catalytic residue [active]
768486001679	tyrosyl-tRNA synthetase; Provisional; Region: PRK13354
768486001680	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
768486001681	active site
768486001682	HIGH motif; other site
768486001683	dimer interface [polypeptide binding]; other site
768486001684	KMSKS motif; other site
768486001685	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
768486001686	RNA binding surface [nucleotide binding]; other site
768486001687	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49); Region: G6PD_bact; pfam10786
768486001688	dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Region: dha_L_ycgS; TIGR02365
768486001689	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
768486001690	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
768486001691	dihydroxyacetone kinase, phosphotransfer subunit; Region: dha_pts; TIGR02364
768486001692	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
768486001693	dipeptidase PepV; Reviewed; Region: PRK07318
768486001694	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
768486001695	active site
768486001696	metal binding site [ion binding]; metal-binding site
768486001697	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
768486001698	putative substrate binding site [chemical binding]; other site
768486001699	putative ATP binding site [chemical binding]; other site
768486001700	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
768486001701	active site
768486001702	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
768486001703	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
768486001704	phospholipase D; Region: PLN02866
768486001705	multiple promoter invertase; Provisional; Region: mpi; PRK13413
768486001706	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
768486001707	catalytic residues [active]
768486001708	catalytic nucleophile [active]
768486001709	Presynaptic Site I dimer interface [polypeptide binding]; other site
768486001710	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
768486001711	Synaptic Flat tetramer interface [polypeptide binding]; other site
768486001712	Synaptic Site I dimer interface [polypeptide binding]; other site
768486001713	DNA binding site [nucleotide binding]
768486001714	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
768486001715	active site
768486001716	DNA binding site [nucleotide binding]
768486001717	Int/Topo IB signature motif; other site
768486001718	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
768486001719	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
768486001720	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
768486001721	Int/Topo IB signature motif; other site
768486001722	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
768486001723	23S rRNA binding site [nucleotide binding]; other site
768486001724	L21 binding site [polypeptide binding]; other site
768486001725	L13 binding site [polypeptide binding]; other site
768486001726	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
768486001727	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
768486001728	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
768486001729	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
768486001730	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
768486001731	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
768486001732	Cl binding site [ion binding]; other site
768486001733	oligomer interface [polypeptide binding]; other site
768486001734	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
768486001735	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
768486001736	Substrate-binding site [chemical binding]; other site
768486001737	Substrate specificity [chemical binding]; other site
768486001738	mevalonate kinase; Region: mevalon_kin; TIGR00549
768486001739	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
768486001740	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
768486001741	diphosphomevalonate decarboxylase; Region: mevDPdecarb; TIGR01240
768486001742	diphosphomevalonate decarboxylase; Region: PLN02407
768486001743	phosphomevalonate kinase, ERG8-type, Gram-positive branch; Region: Pmev_kin_Gr_pos; TIGR01220
768486001744	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
768486001745	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
768486001746	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
768486001747	homotetramer interface [polypeptide binding]; other site
768486001748	FMN binding site [chemical binding]; other site
768486001749	homodimer contacts [polypeptide binding]; other site
768486001750	putative active site [active]
768486001751	putative substrate binding site [chemical binding]; other site
768486001752	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
768486001753	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
768486001754	putative catalytic cysteine [active]
768486001755	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
768486001756	putative active site [active]
768486001757	metal binding site [ion binding]; metal-binding site
768486001758	Preprotein translocase subunit; Region: YajC; cl00806
768486001759	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
768486001760	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
768486001761	Protein of unknown function (DUF975); Region: DUF975; cl10504
768486001762	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
768486001763	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
768486001764	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
768486001765	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
768486001766	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
768486001767	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
768486001768	potential frameshift: common BLAST hit: gi|325970217|ref|YP_004246408.1| NAD-dependent epimerase/dehydratase
768486001769	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
768486001770	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
768486001771	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
768486001772	active site
768486001773	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
768486001774	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
768486001775	putative ADP-binding pocket [chemical binding]; other site
768486001776	Bacterial sugar transferase; Region: Bac_transf; pfam02397
768486001777	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
768486001778	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
768486001779	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
768486001780	active site
768486001781	catalytic site [active]
768486001782	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
768486001783	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
768486001784	Chain length determinant protein; Region: Wzz; cl15801
768486001785	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
768486001786	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
768486001787	choice-of-anchor C domain; Region: choice_anch_C; TIGR04362
768486001788	Viral enhancin protein; Region: Enhancin; pfam03272
768486001789	Peptidase M60-like family; Region: M60-like; pfam13402
768486001790	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
768486001791	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
768486001792	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
768486001793	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
768486001794	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
768486001795	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
768486001796	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
768486001797	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
768486001798	Amino acid permease; Region: AA_permease_2; pfam13520
768486001799	Predicted membrane protein [Function unknown]; Region: COG1511
768486001800	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
768486001801	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
768486001802	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
768486001803	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
768486001804	putative NAD(P) binding site [chemical binding]; other site
768486001805	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
768486001806	PemK-like protein; Region: PemK; pfam02452
768486001807	alanine racemase; Reviewed; Region: alr; PRK00053
768486001808	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
768486001809	active site
768486001810	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
768486001811	dimer interface [polypeptide binding]; other site
768486001812	substrate binding site [chemical binding]; other site
768486001813	catalytic residues [active]
768486001814	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
768486001815	DEAD-like helicases superfamily; Region: DEXDc; smart00487
768486001816	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
768486001817	ATP binding site [chemical binding]; other site
768486001818	Mg++ binding site [ion binding]; other site
768486001819	motif III; other site
768486001820	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
768486001821	nucleotide binding region [chemical binding]; other site
768486001822	ATP-binding site [chemical binding]; other site
768486001823	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
768486001824	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
768486001825	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
768486001826	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
768486001827	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
768486001828	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
768486001829	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
768486001830	Protein of unknown function (DUF2512); Region: DUF2512; pfam10710
768486001831	Uncharacterized BCR, YaiI/YqxD family COG1671; Region: DUF188; cl00727
768486001832	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486001833	Coenzyme A binding pocket [chemical binding]; other site
768486001834	Uncharacterized conserved protein [Function unknown]; Region: COG0398
768486001835	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
768486001836	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
768486001837	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
768486001838	Sugar specificity; other site
768486001839	Pyrimidine base specificity; other site
768486001840	ATP-binding site [chemical binding]; other site
768486001841	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
768486001842	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486001843	motif II; other site
768486001844	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
768486001845	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
768486001846	active site
768486001847	uracil binding [chemical binding]; other site
768486001848	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
768486001849	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
768486001850	5S rRNA interface [nucleotide binding]; other site
768486001851	CTC domain interface [polypeptide binding]; other site
768486001852	L16 interface [polypeptide binding]; other site
768486001853	Staphylococcal protein of unknown function (DUF960); Region: DUF960; pfam06124
768486001854	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
768486001855	putative efflux protein, MATE family; Region: matE; TIGR00797
768486001856	Heat induced stress protein YflT; Region: YflT; pfam11181
768486001857	Domain of unknown function (DUF2382); Region: DUF2382; pfam09557
768486001858	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
768486001859	Domain of unknown function DUF21; Region: DUF21; pfam01595
768486001860	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
768486001861	Transporter associated domain; Region: CorC_HlyC; smart01091
768486001862	K+ potassium transporter; Region: K_trans; cl15781
768486001863	Predicted membrane protein [Function unknown]; Region: COG2261
768486001864	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
768486001865	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
768486001866	RNase E interface [polypeptide binding]; other site
768486001867	trimer interface [polypeptide binding]; other site
768486001868	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
768486001869	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
768486001870	RNase E interface [polypeptide binding]; other site
768486001871	trimer interface [polypeptide binding]; other site
768486001872	active site
768486001873	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
768486001874	putative nucleic acid binding region [nucleotide binding]; other site
768486001875	G-X-X-G motif; other site
768486001876	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
768486001877	RNA binding site [nucleotide binding]; other site
768486001878	domain interface; other site
768486001879	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
768486001880	16S/18S rRNA binding site [nucleotide binding]; other site
768486001881	S13e-L30e interaction site [polypeptide binding]; other site
768486001882	25S rRNA binding site [nucleotide binding]; other site
768486001883	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
768486001884	active site
768486001885	catalytic residues [active]
768486001886	metal binding site [ion binding]; metal-binding site
768486001887	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
768486001888	Predicted small molecule binding protein (contains 3H domain) [General function prediction only]; Region: COG1827
768486001889	HTH domain; Region: HTH_11; pfam08279
768486001890	3H domain; Region: 3H; pfam02829
768486001891	maltose O-acetyltransferase; Provisional; Region: PRK10092
768486001892	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
768486001893	active site
768486001894	substrate binding site [chemical binding]; other site
768486001895	trimer interface [polypeptide binding]; other site
768486001896	CoA binding site [chemical binding]; other site
768486001897	hypothetical protein; Provisional; Region: PRK07248
768486001898	NAD-dependent deacetylase; Provisional; Region: PRK00481
768486001899	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
768486001900	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
768486001901	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
768486001902	substrate binding pocket [chemical binding]; other site
768486001903	membrane-bound complex binding site; other site
768486001904	hinge residues; other site
768486001905	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
768486001906	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486001907	dimer interface [polypeptide binding]; other site
768486001908	conserved gate region; other site
768486001909	putative PBP binding loops; other site
768486001910	ABC-ATPase subunit interface; other site
768486001911	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
768486001912	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
768486001913	Walker A/P-loop; other site
768486001914	ATP binding site [chemical binding]; other site
768486001915	Q-loop/lid; other site
768486001916	ABC transporter signature motif; other site
768486001917	Walker B; other site
768486001918	D-loop; other site
768486001919	H-loop/switch region; other site
768486001920	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
768486001921	Branched-chain amino acid transport protein; Region: Branch_AA_trans; pfam05525
768486001922	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
768486001923	Low molecular weight phosphatase family; Region: LMWPc; cd00115
768486001924	active site
768486001925	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
768486001926	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
768486001927	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
768486001928	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486001929	Walker A motif; other site
768486001930	ATP binding site [chemical binding]; other site
768486001931	Walker B motif; other site
768486001932	arginine finger; other site
768486001933	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
768486001934	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
768486001935	RuvA N terminal domain; Region: RuvA_N; pfam01330
768486001936	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
768486001937	methionine sulfoxide reductase B; Provisional; Region: PRK00222
768486001938	SelR domain; Region: SelR; pfam01641
768486001939	trehalose operon repressor, B. subtilis-type; Region: trehalos_R_Bsub; TIGR02404
768486001940	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
768486001941	DNA-binding site [nucleotide binding]; DNA binding site
768486001942	UTRA domain; Region: UTRA; pfam07702
768486001943	PTS system, trehalose-specific IIBC component; Region: PTS-IIBC-Tre; TIGR01992
768486001944	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
768486001945	active site turn [active]
768486001946	phosphorylation site [posttranslational modification]
768486001947	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
768486001948	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
768486001949	HPr interaction site; other site
768486001950	glycerol kinase (GK) interaction site [polypeptide binding]; other site
768486001951	active site
768486001952	phosphorylation site [posttranslational modification]
768486001953	Maf-like protein; Region: Maf; pfam02545
768486001954	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
768486001955	active site
768486001956	dimer interface [polypeptide binding]; other site
768486001957	DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair]; Region: MutL; COG0323
768486001958	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
768486001959	ATP binding site [chemical binding]; other site
768486001960	Mg2+ binding site [ion binding]; other site
768486001961	G-X-G motif; other site
768486001962	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
768486001963	ATP binding site [chemical binding]; other site
768486001964	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
768486001965	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
768486001966	MutS domain I; Region: MutS_I; pfam01624
768486001967	MutS domain II; Region: MutS_II; pfam05188
768486001968	MutS domain III; Region: MutS_III; pfam05192
768486001969	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
768486001970	Walker A/P-loop; other site
768486001971	ATP binding site [chemical binding]; other site
768486001972	Q-loop/lid; other site
768486001973	ABC transporter signature motif; other site
768486001974	Walker B; other site
768486001975	D-loop; other site
768486001976	H-loop/switch region; other site
768486001977	Protein of unknown function (DUF964); Region: DUF964; cl01483
768486001978	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
768486001979	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
768486001980	putative active site [active]
768486001981	metal binding site [ion binding]; metal-binding site
768486001982	homodimer binding site [polypeptide binding]; other site
768486001983	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486001984	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
768486001985	active site
768486001986	motif I; other site
768486001987	motif II; other site
768486001988	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
768486001989	potential frameshift: common BLAST hit: gi|389867314|ref|YP_006374737.1| DNA alkylation repair protein
768486001990	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
768486001991	A new structural DNA glycosylase; Region: AlkD_like; cl11434
768486001992	active site
768486001993	A new structural DNA glycosylase; Region: AlkD_like; cl11434
768486001994	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
768486001995	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
768486001996	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
768486001997	RNA binding surface [nucleotide binding]; other site
768486001998	BioY family; Region: BioY; pfam02632
768486001999	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
768486002000	QueT transporter; Region: QueT; pfam06177
768486002001	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK06550
768486002002	classical (c) SDRs; Region: SDR_c; cd05233
768486002003	NAD(P) binding site [chemical binding]; other site
768486002004	active site
768486002005	Protein of unknown function (DUF2829); Region: DUF2829; pfam11195
768486002006	Mga helix-turn-helix domain; Region: Mga; pfam05043
768486002007	LrgB-like family; Region: LrgB; pfam04172
768486002008	LrgA family; Region: LrgA; pfam03788
768486002009	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
768486002010	amphipathic channel; other site
768486002011	Asn-Pro-Ala signature motifs; other site
768486002012	putative phosphoesterase; Region: acc_ester; TIGR03729
768486002013	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4918
768486002014	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
768486002015	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
768486002016	ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CeuA; COG4607
768486002017	Siderophore binding protein FatB.  These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins...; Region: FatB; cd01140
768486002018	putative ligand binding residues [chemical binding]; other site
768486002019	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
768486002020	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
768486002021	Walker A/P-loop; other site
768486002022	ATP binding site [chemical binding]; other site
768486002023	Q-loop/lid; other site
768486002024	ABC transporter signature motif; other site
768486002025	Walker B; other site
768486002026	D-loop; other site
768486002027	H-loop/switch region; other site
768486002028	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
768486002029	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
768486002030	ABC-ATPase subunit  interface; other site
768486002031	dimer interface [polypeptide binding]; other site
768486002032	putative PBP binding regions; other site
768486002033	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
768486002034	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
768486002035	ABC-ATPase subunit  interface; other site
768486002036	dimer interface [polypeptide binding]; other site
768486002037	putative PBP binding regions; other site
768486002038	Protein of unknown function (DUF1694); Region: DUF1694; pfam07997
768486002039	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
768486002040	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
768486002041	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486002042	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
768486002043	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
768486002044	bifunctional glutamate--cysteine ligase/glutathione synthetase; Provisional; Region: PRK02471
768486002045	Glutamate-cysteine ligase; Region: Glu_cys_ligase; cl17352
768486002046	ATP-grasp domain; Region: ATP-grasp_4; cl17255
768486002047	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
768486002048	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
768486002049	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
768486002050	P loop; other site
768486002051	GTP binding site [chemical binding]; other site
768486002052	sugar phosphate phosphatase; Provisional; Region: PRK10513
768486002053	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486002054	active site
768486002055	motif I; other site
768486002056	motif II; other site
768486002057	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486002058	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
768486002059	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
768486002060	Walker A/P-loop; other site
768486002061	ATP binding site [chemical binding]; other site
768486002062	Q-loop/lid; other site
768486002063	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
768486002064	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
768486002065	ABC transporter signature motif; other site
768486002066	Walker B; other site
768486002067	D-loop; other site
768486002068	H-loop/switch region; other site
768486002069	ribonuclease III; Reviewed; Region: rnc; PRK00102
768486002070	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
768486002071	dimerization interface [polypeptide binding]; other site
768486002072	active site
768486002073	metal binding site [ion binding]; metal-binding site
768486002074	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
768486002075	dsRNA binding site [nucleotide binding]; other site
768486002076	The substrate binding component of an ABC-type lactococcal OppA-like transport system contains; Region: PBP2_Lactococcal_OppA_like; cd08510
768486002077	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
768486002078	peptide binding site [polypeptide binding]; other site
768486002079	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
768486002080	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486002081	dimer interface [polypeptide binding]; other site
768486002082	conserved gate region; other site
768486002083	putative PBP binding loops; other site
768486002084	ABC-ATPase subunit interface; other site
768486002085	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
768486002086	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486002087	dimer interface [polypeptide binding]; other site
768486002088	conserved gate region; other site
768486002089	putative PBP binding loops; other site
768486002090	ABC-ATPase subunit interface; other site
768486002091	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
768486002092	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
768486002093	Walker A/P-loop; other site
768486002094	ATP binding site [chemical binding]; other site
768486002095	Q-loop/lid; other site
768486002096	ABC transporter signature motif; other site
768486002097	Walker B; other site
768486002098	D-loop; other site
768486002099	H-loop/switch region; other site
768486002100	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
768486002101	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
768486002102	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
768486002103	Walker A/P-loop; other site
768486002104	ATP binding site [chemical binding]; other site
768486002105	Q-loop/lid; other site
768486002106	ABC transporter signature motif; other site
768486002107	Walker B; other site
768486002108	D-loop; other site
768486002109	H-loop/switch region; other site
768486002110	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
768486002111	acyl carrier protein; Provisional; Region: acpP; PRK00982
768486002112	putative phosphate acyltransferase; Provisional; Region: PRK05331
768486002113	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
768486002114	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
768486002115	generic binding surface II; other site
768486002116	ssDNA binding site; other site
768486002117	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
768486002118	ATP binding site [chemical binding]; other site
768486002119	putative Mg++ binding site [ion binding]; other site
768486002120	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
768486002121	nucleotide binding region [chemical binding]; other site
768486002122	ATP-binding site [chemical binding]; other site
768486002123	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
768486002124	DAK2 domain; Region: Dak2; pfam02734
768486002125	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
768486002126	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
768486002127	potential frameshift: common BLAST hit: gi|332685566|ref|YP_004455340.1| ABC transporter permease
768486002128	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
768486002129	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
768486002130	dimerization interface 3.5A [polypeptide binding]; other site
768486002131	active site
768486002132	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
768486002133	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13634
768486002134	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
768486002135	Walker A/P-loop; other site
768486002136	ATP binding site [chemical binding]; other site
768486002137	Q-loop/lid; other site
768486002138	ABC transporter signature motif; other site
768486002139	Walker B; other site
768486002140	D-loop; other site
768486002141	H-loop/switch region; other site
768486002142	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13635
768486002143	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
768486002144	Walker A/P-loop; other site
768486002145	ATP binding site [chemical binding]; other site
768486002146	Q-loop/lid; other site
768486002147	ABC transporter signature motif; other site
768486002148	Walker B; other site
768486002149	D-loop; other site
768486002150	H-loop/switch region; other site
768486002151	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
768486002152	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
768486002153	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
768486002154	alphaNTD homodimer interface [polypeptide binding]; other site
768486002155	alphaNTD - beta interaction site [polypeptide binding]; other site
768486002156	alphaNTD - beta' interaction site [polypeptide binding]; other site
768486002157	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
768486002158	potential frameshift: common BLAST hit: gi|29374877|ref|NP_814030.1| DNA-directed RNA polymerase subunit alpha
768486002159	30S ribosomal protein S11; Validated; Region: PRK05309
768486002160	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
768486002161	30S ribosomal protein S13; Region: bact_S13; TIGR03631
768486002162	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
768486002163	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
768486002164	rRNA binding site [nucleotide binding]; other site
768486002165	predicted 30S ribosome binding site; other site
768486002166	adenylate kinase; Reviewed; Region: adk; PRK00279
768486002167	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
768486002168	AMP-binding site [chemical binding]; other site
768486002169	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
768486002170	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
768486002171	SecY translocase; Region: SecY; pfam00344
768486002172	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
768486002173	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
768486002174	23S rRNA binding site [nucleotide binding]; other site
768486002175	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
768486002176	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
768486002177	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
768486002178	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
768486002179	5S rRNA interface [nucleotide binding]; other site
768486002180	L27 interface [polypeptide binding]; other site
768486002181	23S rRNA interface [nucleotide binding]; other site
768486002182	L5 interface [polypeptide binding]; other site
768486002183	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
768486002184	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
768486002185	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
768486002186	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
768486002187	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
768486002188	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
768486002189	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
768486002190	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
768486002191	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
768486002192	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
768486002193	RNA binding site [nucleotide binding]; other site
768486002194	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
768486002195	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
768486002196	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
768486002197	23S rRNA interface [nucleotide binding]; other site
768486002198	putative translocon interaction site; other site
768486002199	signal recognition particle (SRP54) interaction site; other site
768486002200	L23 interface [polypeptide binding]; other site
768486002201	trigger factor interaction site; other site
768486002202	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
768486002203	23S rRNA interface [nucleotide binding]; other site
768486002204	5S rRNA interface [nucleotide binding]; other site
768486002205	putative antibiotic binding site [chemical binding]; other site
768486002206	L25 interface [polypeptide binding]; other site
768486002207	L27 interface [polypeptide binding]; other site
768486002208	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
768486002209	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
768486002210	G-X-X-G motif; other site
768486002211	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
768486002212	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
768486002213	putative translocon binding site; other site
768486002214	protein-rRNA interface [nucleotide binding]; other site
768486002215	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
768486002216	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
768486002217	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
768486002218	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
768486002219	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
768486002220	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
768486002221	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
768486002222	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
768486002223	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
768486002224	intersubunit interface [polypeptide binding]; other site
768486002225	active site
768486002226	zinc binding site [ion binding]; other site
768486002227	Na+ binding site [ion binding]; other site
768486002228	potential frameshift: common BLAST hit: gi|116873569|ref|YP_850350.1| fructose-bisphosphate aldolase
768486002229	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
768486002230	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
768486002231	active site
768486002232	P-loop; other site
768486002233	phosphorylation site [posttranslational modification]
768486002234	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
768486002235	active site
768486002236	phosphorylation site [posttranslational modification]
768486002237	potential frameshift: common BLAST hit: gi|289435488|ref|YP_003465360.1| DNA-binding/PRD domain protein
768486002238	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
768486002239	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
768486002240	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
768486002241	active site turn [active]
768486002242	phosphorylation site [posttranslational modification]
768486002243	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
768486002244	HPr interaction site; other site
768486002245	glycerol kinase (GK) interaction site [polypeptide binding]; other site
768486002246	active site
768486002247	phosphorylation site [posttranslational modification]
768486002248	transcriptional antiterminator BglG; Provisional; Region: PRK09772
768486002249	CAT RNA binding domain; Region: CAT_RBD; smart01061
768486002250	PRD domain; Region: PRD; pfam00874
768486002251	PRD domain; Region: PRD; pfam00874
768486002252	elongation factor Tu; Reviewed; Region: PRK00049
768486002253	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
768486002254	G1 box; other site
768486002255	GEF interaction site [polypeptide binding]; other site
768486002256	GTP/Mg2+ binding site [chemical binding]; other site
768486002257	Switch I region; other site
768486002258	G2 box; other site
768486002259	G3 box; other site
768486002260	Switch II region; other site
768486002261	G4 box; other site
768486002262	G5 box; other site
768486002263	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
768486002264	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
768486002265	Antibiotic Binding Site [chemical binding]; other site
768486002266	elongation factor G; Reviewed; Region: PRK00007
768486002267	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
768486002268	G1 box; other site
768486002269	putative GEF interaction site [polypeptide binding]; other site
768486002270	GTP/Mg2+ binding site [chemical binding]; other site
768486002271	Switch I region; other site
768486002272	G2 box; other site
768486002273	G3 box; other site
768486002274	Switch II region; other site
768486002275	G4 box; other site
768486002276	G5 box; other site
768486002277	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
768486002278	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
768486002279	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
768486002280	30S ribosomal protein S7; Validated; Region: PRK05302
768486002281	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
768486002282	S17 interaction site [polypeptide binding]; other site
768486002283	S8 interaction site; other site
768486002284	16S rRNA interaction site [nucleotide binding]; other site
768486002285	streptomycin interaction site [chemical binding]; other site
768486002286	23S rRNA interaction site [nucleotide binding]; other site
768486002287	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
768486002288	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
768486002289	tetramer (dimer of dimers) interface [polypeptide binding]; other site
768486002290	active site
768486002291	dimer interface [polypeptide binding]; other site
768486002292	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
768486002293	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
768486002294	catalytic residues [active]
768486002295	catalytic nucleophile [active]
768486002296	Presynaptic Site I dimer interface [polypeptide binding]; other site
768486002297	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
768486002298	Synaptic Flat tetramer interface [polypeptide binding]; other site
768486002299	Synaptic Site I dimer interface [polypeptide binding]; other site
768486002300	DNA binding site [nucleotide binding]
768486002301	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
768486002302	catalytic core [active]
768486002303	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
768486002304	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
768486002305	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
768486002306	purine nucleoside phosphorylase; Provisional; Region: PRK08202
768486002307	phosphopentomutase; Provisional; Region: PRK05362
768486002308	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
768486002309	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
768486002310	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
768486002311	TM-ABC transporter signature motif; other site
768486002312	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
768486002313	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
768486002314	TM-ABC transporter signature motif; other site
768486002315	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
768486002316	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
768486002317	Walker A/P-loop; other site
768486002318	ATP binding site [chemical binding]; other site
768486002319	Q-loop/lid; other site
768486002320	ABC transporter signature motif; other site
768486002321	Walker B; other site
768486002322	D-loop; other site
768486002323	H-loop/switch region; other site
768486002324	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
768486002325	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
768486002326	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
768486002327	ligand binding site [chemical binding]; other site
768486002328	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
768486002329	active site
768486002330	catalytic motif [active]
768486002331	Zn binding site [ion binding]; other site
768486002332	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
768486002333	intersubunit interface [polypeptide binding]; other site
768486002334	active site
768486002335	catalytic residue [active]
768486002336	pyrimidine-nucleoside phosphorylase; Reviewed; Region: PRK06078
768486002337	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
768486002338	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
768486002339	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
768486002340	Transcriptional regulators [Transcription]; Region: PurR; COG1609
768486002341	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
768486002342	DNA binding site [nucleotide binding]
768486002343	domain linker motif; other site
768486002344	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
768486002345	dimerization interface [polypeptide binding]; other site
768486002346	ligand binding site [chemical binding]; other site
768486002347	16S RNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; Region: RsmC; COG2813
768486002348	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486002349	S-adenosylmethionine binding site [chemical binding]; other site
768486002350	pantothenate kinase; Provisional; Region: PRK05439
768486002351	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
768486002352	ATP-binding site [chemical binding]; other site
768486002353	CoA-binding site [chemical binding]; other site
768486002354	Mg2+-binding site [ion binding]; other site
768486002355	GMP synthase; Reviewed; Region: guaA; PRK00074
768486002356	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
768486002357	AMP/PPi binding site [chemical binding]; other site
768486002358	candidate oxyanion hole; other site
768486002359	catalytic triad [active]
768486002360	potential glutamine specificity residues [chemical binding]; other site
768486002361	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
768486002362	ATP Binding subdomain [chemical binding]; other site
768486002363	Dimerization subdomain; other site
768486002364	Mga helix-turn-helix domain; Region: Mga; pfam05043
768486002365	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
768486002366	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
768486002367	ZIP Zinc transporter; Region: Zip; pfam02535
768486002368	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
768486002369	pyruvate oxidase; Region: pyruv_oxi_spxB; TIGR02720
768486002370	PYR/PP interface [polypeptide binding]; other site
768486002371	dimer interface [polypeptide binding]; other site
768486002372	tetramer interface [polypeptide binding]; other site
768486002373	TPP binding site [chemical binding]; other site
768486002374	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
768486002375	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
768486002376	TPP-binding site [chemical binding]; other site
768486002377	Short repeat of unknown function (DUF308); Region: DUF308; cl15828
768486002378	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
768486002379	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486002380	Walker A/P-loop; other site
768486002381	ATP binding site [chemical binding]; other site
768486002382	Q-loop/lid; other site
768486002383	ABC transporter signature motif; other site
768486002384	Walker B; other site
768486002385	D-loop; other site
768486002386	H-loop/switch region; other site
768486002387	ABC transporter; Region: ABC_tran_2; pfam12848
768486002388	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
768486002389	EDD domain protein, DegV family; Region: DegV; TIGR00762
768486002390	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
768486002391	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
768486002392	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
768486002393	GDP-binding site [chemical binding]; other site
768486002394	ACT binding site; other site
768486002395	IMP binding site; other site
768486002396	replicative DNA helicase; Provisional; Region: PRK05748
768486002397	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
768486002398	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
768486002399	Walker A motif; other site
768486002400	ATP binding site [chemical binding]; other site
768486002401	Walker B motif; other site
768486002402	DNA binding loops [nucleotide binding]
768486002403	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
768486002404	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
768486002405	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
768486002406	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
768486002407	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
768486002408	DHH family; Region: DHH; pfam01368
768486002409	DHHA1 domain; Region: DHHA1; pfam02272
768486002410	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
768486002411	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
768486002412	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
768486002413	dimer interface [polypeptide binding]; other site
768486002414	ssDNA binding site [nucleotide binding]; other site
768486002415	tetramer (dimer of dimers) interface [polypeptide binding]; other site
768486002416	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
768486002417	DNA gyrase subunit A; Validated; Region: PRK05560
768486002418	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
768486002419	CAP-like domain; other site
768486002420	active site
768486002421	primary dimer interface [polypeptide binding]; other site
768486002422	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
768486002423	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
768486002424	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
768486002425	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
768486002426	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
768486002427	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
768486002428	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
768486002429	Mg2+ binding site [ion binding]; other site
768486002430	G-X-G motif; other site
768486002431	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
768486002432	anchoring element; other site
768486002433	dimer interface [polypeptide binding]; other site
768486002434	ATP binding site [chemical binding]; other site
768486002435	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
768486002436	active site
768486002437	putative metal-binding site [ion binding]; other site
768486002438	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
768486002439	S4 domain protein YaaA; Region: YaaA_near_RecF; TIGR02988
768486002440	DNA polymerase III subunit beta; Validated; Region: PRK05643
768486002441	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
768486002442	putative DNA binding surface [nucleotide binding]; other site
768486002443	dimer interface [polypeptide binding]; other site
768486002444	beta-clamp/clamp loader binding surface; other site
768486002445	beta-clamp/translesion DNA polymerase binding surface; other site
768486002446	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
768486002447	DnaA N-terminal domain; Region: DnaA_N; pfam11638
768486002448	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486002449	Walker A motif; other site
768486002450	ATP binding site [chemical binding]; other site
768486002451	Walker B motif; other site
768486002452	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
768486002453	arginine finger; other site
768486002454	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
768486002455	DnaA box-binding interface [nucleotide binding]; other site
768486002456	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
768486002457	ribonuclease P; Reviewed; Region: rnpA; PRK00499
768486002458	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
768486002459	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
768486002460	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
768486002461	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
768486002462	G-X-X-G motif; other site
768486002463	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
768486002464	RxxxH motif; other site
768486002465	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
768486002466	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
768486002467	trmE is a tRNA modification GTPase; Region: trmE; cd04164
768486002468	G1 box; other site
768486002469	GTP/Mg2+ binding site [chemical binding]; other site
768486002470	Switch I region; other site
768486002471	G2 box; other site
768486002472	Switch II region; other site
768486002473	G3 box; other site
768486002474	G4 box; other site
768486002475	G5 box; other site
768486002476	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
768486002477	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
768486002478	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
768486002479	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
768486002480	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
768486002481	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
768486002482	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
768486002483	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
768486002484	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
768486002485	P-loop; other site
768486002486	Magnesium ion binding site [ion binding]; other site
768486002487	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
768486002488	Magnesium ion binding site [ion binding]; other site
768486002489	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
768486002490	potential frameshift: common BLAST hit: gi|332687255|ref|YP_004457029.1| chromosome (plasmid) partitioning protein ParB/ stage 0 sporulation
768486002491	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
768486002492	GTP-binding protein YchF; Reviewed; Region: PRK09601
768486002493	YchF GTPase; Region: YchF; cd01900
768486002494	G1 box; other site
768486002495	GTP/Mg2+ binding site [chemical binding]; other site
768486002496	Switch I region; other site
768486002497	G2 box; other site
768486002498	Switch II region; other site
768486002499	G3 box; other site
768486002500	G4 box; other site
768486002501	G5 box; other site
768486002502	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
768486002503	Protein of unknown function (DUF1129); Region: DUF1129; pfam06570
768486002504	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
768486002505	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
768486002506	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
768486002507	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
768486002508	active site
768486002509	seryl-tRNA synthetase; Provisional; Region: PRK05431
768486002510	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
768486002511	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
768486002512	dimer interface [polypeptide binding]; other site
768486002513	active site
768486002514	motif 1; other site
768486002515	motif 2; other site
768486002516	motif 3; other site
768486002517	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
768486002518	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
768486002519	dimer interface [polypeptide binding]; other site
768486002520	phosphorylation site [posttranslational modification]
768486002521	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
768486002522	ATP binding site [chemical binding]; other site
768486002523	Mg2+ binding site [ion binding]; other site
768486002524	G-X-G motif; other site
768486002525	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
768486002526	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486002527	active site
768486002528	phosphorylation site [posttranslational modification]
768486002529	intermolecular recognition site; other site
768486002530	dimerization interface [polypeptide binding]; other site
768486002531	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
768486002532	DNA binding site [nucleotide binding]
768486002533	Firmicute transcriptional repressor of class III stress genes (CtsR); Region: CtsR; pfam05848
768486002534	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
768486002535	Clp amino terminal domain; Region: Clp_N; pfam02861
768486002536	Clp amino terminal domain; Region: Clp_N; pfam02861
768486002537	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486002538	Walker A motif; other site
768486002539	ATP binding site [chemical binding]; other site
768486002540	Walker B motif; other site
768486002541	arginine finger; other site
768486002542	UvrB/uvrC motif; Region: UVR; pfam02151
768486002543	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486002544	Walker A motif; other site
768486002545	ATP binding site [chemical binding]; other site
768486002546	Walker B motif; other site
768486002547	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
768486002548	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
768486002549	Peptidase family U32; Region: Peptidase_U32; pfam01136
768486002550	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
768486002551	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
768486002552	Peptidase family U32; Region: Peptidase_U32; pfam01136
768486002553	glutathione reductase; Validated; Region: PRK06116
768486002554	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
768486002555	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
768486002556	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
768486002557	Mga helix-turn-helix domain; Region: Mga; pfam05043
768486002558	Mga helix-turn-helix domain; Region: Mga; pfam05043
768486002559	Type IV secretion-system coupling protein DNA-binding domain; Region: TrwB_AAD_bind; pfam10412
768486002560	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
768486002561	Walker A motif; other site
768486002562	ATP binding site [chemical binding]; other site
768486002563	Walker B motif; other site
768486002564	PrgI family protein; Region: PrgI; pfam12666
768486002565	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
768486002566	AAA-like domain; Region: AAA_10; pfam12846
768486002567	Domain of unknown function DUF87; Region: DUF87; pfam01935
768486002568	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
768486002569	N-acetyl-D-glucosamine binding site [chemical binding]; other site
768486002570	catalytic residue [active]
768486002571	Uncharacterized protein conserved in bacteria (DUF2272); Region: DUF2272; cl01776
768486002572	1,4-dihydroxy-2-naphthoate octaprenyltransferase [Coenzyme metabolism]; Region: MenA; cl17224
768486002573	UbiA prenyltransferase family; Region: UbiA; pfam01040
768486002574	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
768486002575	ApbE family; Region: ApbE; pfam02424
768486002576	This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins; Region: FMN_bind; smart00900
768486002577	This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins; Region: FMN_bind; smart00900
768486002578	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
768486002579	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
768486002580	Listerrria innocua Lin0431  is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (DII); Region: Lin0431_like; cd09911
768486002581	trimer interface [polypeptide binding]; other site
768486002582	Heptaprenyl diphosphate synthase component I; Region: Hpre_diP_synt_I; pfam07456
768486002583	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
768486002584	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
768486002585	substrate binding pocket [chemical binding]; other site
768486002586	chain length determination region; other site
768486002587	substrate-Mg2+ binding site; other site
768486002588	catalytic residues [active]
768486002589	aspartate-rich region 1; other site
768486002590	active site lid residues [active]
768486002591	aspartate-rich region 2; other site
768486002592	potential frameshift: common BLAST hit: gi|29377684|ref|NP_816838.1| BirA bifunctional protein
768486002593	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
768486002594	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486002595	Walker A/P-loop; other site
768486002596	ATP binding site [chemical binding]; other site
768486002597	Q-loop/lid; other site
768486002598	ABC transporter signature motif; other site
768486002599	Walker B; other site
768486002600	D-loop; other site
768486002601	H-loop/switch region; other site
768486002602	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
768486002603	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
768486002604	TM-ABC transporter signature motif; other site
768486002605	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
768486002606	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
768486002607	zinc binding site [ion binding]; other site
768486002608	putative ligand binding site [chemical binding]; other site
768486002609	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
768486002610	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
768486002611	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
768486002612	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
768486002613	RPB1 interaction site [polypeptide binding]; other site
768486002614	RPB10 interaction site [polypeptide binding]; other site
768486002615	RPB11 interaction site [polypeptide binding]; other site
768486002616	RPB3 interaction site [polypeptide binding]; other site
768486002617	RPB12 interaction site [polypeptide binding]; other site
768486002618	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
768486002619	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
768486002620	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
768486002621	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
768486002622	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
768486002623	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
768486002624	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
768486002625	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
768486002626	DNA binding site [nucleotide binding]
768486002627	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
768486002628	methionine sulfoxide reductase A; Provisional; Region: PRK14054
768486002629	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
768486002630	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
768486002631	gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314
768486002632	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
768486002633	N- and C-terminal domain interface [polypeptide binding]; other site
768486002634	active site
768486002635	catalytic site [active]
768486002636	metal binding site [ion binding]; metal-binding site
768486002637	carbohydrate binding site [chemical binding]; other site
768486002638	ATP binding site [chemical binding]; other site
768486002639	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
768486002640	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
768486002641	dimerization interface [polypeptide binding]; other site
768486002642	DPS ferroxidase diiron center [ion binding]; other site
768486002643	ion pore; other site
768486002644	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
768486002645	23S rRNA interface [nucleotide binding]; other site
768486002646	L3 interface [polypeptide binding]; other site
768486002647	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
768486002648	Toxin Fst, type I toxin-antitoxin system; Region: Fst_toxin; pfam13955
768486002649	HTH domain; Region: HTH_11; cl17392
768486002650	PRD domain; Region: PRD; pfam00874
768486002651	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
768486002652	active site
768486002653	P-loop; other site
768486002654	phosphorylation site [posttranslational modification]
768486002655	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
768486002656	active site
768486002657	phosphorylation site [posttranslational modification]
768486002658	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
768486002659	active site
768486002660	phosphorylation site [posttranslational modification]
768486002661	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
768486002662	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
768486002663	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
768486002664	active site
768486002665	P-loop; other site
768486002666	phosphorylation site [posttranslational modification]
768486002667	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
768486002668	intersubunit interface [polypeptide binding]; other site
768486002669	active site
768486002670	zinc binding site [ion binding]; other site
768486002671	Na+ binding site [ion binding]; other site
768486002672	triosephosphate isomerase; Provisional; Region: PRK04302
768486002673	phosphate binding site [ion binding]; other site
768486002674	Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894
768486002675	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
768486002676	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486002677	active site
768486002678	phosphorylation site [posttranslational modification]
768486002679	intermolecular recognition site; other site
768486002680	dimerization interface [polypeptide binding]; other site
768486002681	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
768486002682	DNA binding residues [nucleotide binding]
768486002683	dimerization interface [polypeptide binding]; other site
768486002684	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
768486002685	Histidine kinase; Region: HisKA_3; pfam07730
768486002686	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
768486002687	ATP binding site [chemical binding]; other site
768486002688	Mg2+ binding site [ion binding]; other site
768486002689	G-X-G motif; other site
768486002690	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
768486002691	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
768486002692	Walker A/P-loop; other site
768486002693	ATP binding site [chemical binding]; other site
768486002694	Q-loop/lid; other site
768486002695	ABC transporter signature motif; other site
768486002696	Walker B; other site
768486002697	D-loop; other site
768486002698	H-loop/switch region; other site
768486002699	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
768486002700	beta-galactosidase; Region: BGL; TIGR03356
768486002701	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
768486002702	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486002703	Walker A/P-loop; other site
768486002704	ATP binding site [chemical binding]; other site
768486002705	Q-loop/lid; other site
768486002706	ABC transporter signature motif; other site
768486002707	Walker B; other site
768486002708	D-loop; other site
768486002709	H-loop/switch region; other site
768486002710	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
768486002711	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
768486002712	Walker A/P-loop; other site
768486002713	ATP binding site [chemical binding]; other site
768486002714	Q-loop/lid; other site
768486002715	ABC transporter signature motif; other site
768486002716	Walker B; other site
768486002717	D-loop; other site
768486002718	H-loop/switch region; other site
768486002719	inner membrane transport permease; Provisional; Region: PRK15066
768486002720	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
768486002721	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486002722	Coenzyme A binding pocket [chemical binding]; other site
768486002723	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
768486002724	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
768486002725	FMN binding site [chemical binding]; other site
768486002726	active site
768486002727	catalytic residues [active]
768486002728	substrate binding site [chemical binding]; other site
768486002729	phytoene desaturase; Region: crtI_fam; TIGR02734
768486002730	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
768486002731	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
768486002732	active site lid residues [active]
768486002733	substrate binding pocket [chemical binding]; other site
768486002734	catalytic residues [active]
768486002735	substrate-Mg2+ binding site; other site
768486002736	aspartate-rich region 1; other site
768486002737	aspartate-rich region 2; other site
768486002738	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4842
768486002739	WXG100 protein secretion system (Wss), protein YukD; Region: YukD; cl17489
768486002740	WXG100 protein secretion system (Wss), protein YukC; Region: YukC; cl01868
768486002741	potential frameshift: common BLAST hit: gi|337738916|ref|YP_004638363.1| DNA segregation ATPase
768486002742	Predicted transcriptional regulator [Transcription]; Region: COG1959
768486002743	Transcriptional regulator; Region: Rrf2; pfam02082
768486002744	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
768486002745	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
768486002746	NADP binding site [chemical binding]; other site
768486002747	Predicted transcriptional regulators [Transcription]; Region: COG1695
768486002748	Transcriptional regulator PadR-like family; Region: PadR; cl17335
768486002749	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
768486002750	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486002751	Major Facilitator Superfamily; Region: MFS_1; pfam07690
768486002752	putative substrate translocation pore; other site
768486002753	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
768486002754	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
768486002755	putative catalytic cysteine [active]
768486002756	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
768486002757	nucleotide binding site [chemical binding]; other site
768486002758	homotetrameric interface [polypeptide binding]; other site
768486002759	putative phosphate binding site [ion binding]; other site
768486002760	putative allosteric binding site; other site
768486002761	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
768486002762	trimer interface [polypeptide binding]; other site
768486002763	active site
768486002764	DNA repair protein RadA; Provisional; Region: PRK11823
768486002765	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
768486002766	Walker A motif/ATP binding site; other site
768486002767	ATP binding site [chemical binding]; other site
768486002768	Walker B motif; other site
768486002769	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
768486002770	Integral membrane protein (PIN domain superfamily) [General function prediction only]; Region: COG4956
768486002771	PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877
768486002772	putative active site [active]
768486002773	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
768486002774	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
768486002775	HIGH motif; other site
768486002776	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
768486002777	active site
768486002778	KMSKS motif; other site
768486002779	serine O-acetyltransferase; Region: cysE; TIGR01172
768486002780	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
768486002781	trimer interface [polypeptide binding]; other site
768486002782	active site
768486002783	substrate binding site [chemical binding]; other site
768486002784	CoA binding site [chemical binding]; other site
768486002785	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
768486002786	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
768486002787	active site
768486002788	HIGH motif; other site
768486002789	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
768486002790	KMSKS motif; other site
768486002791	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
768486002792	tRNA binding surface [nucleotide binding]; other site
768486002793	anticodon binding site; other site
768486002794	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
768486002795	active site
768486002796	metal binding site [ion binding]; metal-binding site
768486002797	dimerization interface [polypeptide binding]; other site
768486002798	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
768486002799	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
768486002800	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
768486002801	YacP-like NYN domain; Region: NYN_YacP; pfam05991
768486002802	RNA polymerase factor sigma-70; Validated; Region: PRK08295
768486002803	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
768486002804	Protein of unknown function (DUF1021); Region: DUF1021; pfam06257
768486002805	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
768486002806	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
768486002807	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
768486002808	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
768486002809	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
768486002810	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
768486002811	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
768486002812	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
768486002813	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
768486002814	Helix-turn-helix domain; Region: HTH_25; pfam13413
768486002815	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
768486002816	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Region: pgsA; TIGR00560
768486002817	competence damage-inducible protein A; Provisional; Region: PRK00549
768486002818	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
768486002819	putative MPT binding site; other site
768486002820	Competence-damaged protein; Region: CinA; pfam02464
768486002821	recombinase A; Provisional; Region: recA; PRK09354
768486002822	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
768486002823	hexamer interface [polypeptide binding]; other site
768486002824	Walker A motif; other site
768486002825	ATP binding site [chemical binding]; other site
768486002826	Walker B motif; other site
768486002827	Domain of unknown function (DUF3552); Region: DUF3552; pfam12072
768486002828	Lyase class I_like superfamily: contains the lyase class I family, histidine ammonia-lyase and phenylalanine ammonia-lyase, which catalyze similar beta-elimination reactions; Region: Lyase_I_like; cl00013
768486002829	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
768486002830	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
768486002831	Zn2+ binding site [ion binding]; other site
768486002832	Mg2+ binding site [ion binding]; other site
768486002833	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
768486002834	Lanthionine synthetase C-like protein; Region: LANC_like; pfam05147
768486002835	active site
768486002836	zinc binding site [ion binding]; other site
768486002837	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
768486002838	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
768486002839	Predicted integral membrane protein [Function unknown]; Region: COG0392
768486002840	Uncharacterized conserved protein [Function unknown]; Region: COG2898
768486002841	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
768486002842	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
768486002843	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
768486002844	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
768486002845	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
768486002846	Metal binding protein AcdA.  These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AcdA proteins belong to the TroA superfamily of helical backbone metal receptor...; Region: AdcA; cd01017
768486002847	metal binding site [ion binding]; metal-binding site
768486002848	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
768486002849	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
768486002850	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
768486002851	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
768486002852	ABC-ATPase subunit  interface; other site
768486002853	dimer interface [polypeptide binding]; other site
768486002854	putative PBP binding regions; other site
768486002855	pur operon repressor; Provisional; Region: PRK09213
768486002856	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
768486002857	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
768486002858	active site
768486002859	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
768486002860	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
768486002861	Substrate binding site; other site
768486002862	Mg++ binding site; other site
768486002863	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
768486002864	active site
768486002865	substrate binding site [chemical binding]; other site
768486002866	CoA binding site [chemical binding]; other site
768486002867	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
768486002868	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
768486002869	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
768486002870	active site
768486002871	Thiamine transporter protein (Thia_YuaJ); Region: Thia_YuaJ; pfam09515
768486002872	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
768486002873	nucleophile elbow; other site
768486002874	Uncharacterized protein conserved in bacteria (DUF2128); Region: DUF2128; pfam09901
768486002875	hypothetical protein; Provisional; Region: PRK11820
768486002876	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
768486002877	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
768486002878	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
768486002879	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
768486002880	catalytic site [active]
768486002881	G-X2-G-X-G-K; other site
768486002882	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
768486002883	primosome assembly protein PriA; Validated; Region: PRK05580
768486002884	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
768486002885	primosomal protein N' Region: priA; TIGR00595
768486002886	ATP binding site [chemical binding]; other site
768486002887	putative Mg++ binding site [ion binding]; other site
768486002888	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
768486002889	nucleotide binding region [chemical binding]; other site
768486002890	ATP-binding site [chemical binding]; other site
768486002891	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
768486002892	active site
768486002893	catalytic residues [active]
768486002894	metal binding site [ion binding]; metal-binding site
768486002895	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
768486002896	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
768486002897	putative active site [active]
768486002898	substrate binding site [chemical binding]; other site
768486002899	putative cosubstrate binding site; other site
768486002900	catalytic site [active]
768486002901	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
768486002902	substrate binding site [chemical binding]; other site
768486002903	16S rRNA methyltransferase B; Provisional; Region: PRK14902
768486002904	NusB family; Region: NusB; pfam01029
768486002905	putative RNA binding site [nucleotide binding]; other site
768486002906	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486002907	S-adenosylmethionine binding site [chemical binding]; other site
768486002908	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
768486002909	active site
768486002910	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
768486002911	Catalytic domain of Protein Kinases; Region: PKc; cd00180
768486002912	active site
768486002913	ATP binding site [chemical binding]; other site
768486002914	substrate binding site [chemical binding]; other site
768486002915	activation loop (A-loop); other site
768486002916	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
768486002917	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
768486002918	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
768486002919	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
768486002920	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
768486002921	GTPase RsgA; Reviewed; Region: PRK00098
768486002922	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
768486002923	RNA binding site [nucleotide binding]; other site
768486002924	homodimer interface [polypeptide binding]; other site
768486002925	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
768486002926	GTPase/Zn-binding domain interface [polypeptide binding]; other site
768486002927	GTP/Mg2+ binding site [chemical binding]; other site
768486002928	G4 box; other site
768486002929	G5 box; other site
768486002930	G1 box; other site
768486002931	Switch I region; other site
768486002932	G2 box; other site
768486002933	G3 box; other site
768486002934	Switch II region; other site
768486002935	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
768486002936	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
768486002937	substrate binding site [chemical binding]; other site
768486002938	hexamer interface [polypeptide binding]; other site
768486002939	metal binding site [ion binding]; metal-binding site
768486002940	Thiamine pyrophosphokinase; Region: TPK; cd07995
768486002941	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
768486002942	active site
768486002943	dimerization interface [polypeptide binding]; other site
768486002944	thiamine binding site [chemical binding]; other site
768486002945	rod shape-determining protein MreC; Provisional; Region: PRK13922
768486002946	rod shape-determining protein MreC; Region: MreC; pfam04085
768486002947	rod shape-determining protein MreD; Region: MreD; pfam04093
768486002948	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
768486002949	Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cl02488
768486002950	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
768486002951	NlpC/P60 family; Region: NLPC_P60; pfam00877
768486002952	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
768486002953	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_2; cd09607
768486002954	active site
768486002955	Zn binding site [ion binding]; other site
768486002956	Predicted integral membrane protein [Function unknown]; Region: COG5652
768486002957	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
768486002958	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
768486002959	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
768486002960	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
768486002961	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
768486002962	tetramer (dimer of dimers) interface [polypeptide binding]; other site
768486002963	NAD binding site [chemical binding]; other site
768486002964	dimer interface [polypeptide binding]; other site
768486002965	substrate binding site [chemical binding]; other site
768486002966	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
768486002967	putative active site [active]
768486002968	catalytic residue [active]
768486002969	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
768486002970	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
768486002971	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
768486002972	ATP binding site [chemical binding]; other site
768486002973	putative Mg++ binding site [ion binding]; other site
768486002974	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
768486002975	nucleotide binding region [chemical binding]; other site
768486002976	ATP-binding site [chemical binding]; other site
768486002977	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
768486002978	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
768486002979	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
768486002980	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
768486002981	RNA binding surface [nucleotide binding]; other site
768486002982	Septum formation initiator; Region: DivIC; pfam04977
768486002983	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
768486002984	hypothetical protein; Provisional; Region: PRK08582
768486002985	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
768486002986	RNA binding site [nucleotide binding]; other site
768486002987	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
768486002988	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
768486002989	Ligand Binding Site [chemical binding]; other site
768486002990	TilS substrate C-terminal domain; Region: TilS_C; smart00977
768486002991	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
768486002992	active site
768486002993	FtsH Extracellular; Region: FtsH_ext; pfam06480
768486002994	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
768486002995	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486002996	Walker A motif; other site
768486002997	ATP binding site [chemical binding]; other site
768486002998	Walker B motif; other site
768486002999	arginine finger; other site
768486003000	Peptidase family M41; Region: Peptidase_M41; pfam01434
768486003001	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
768486003002	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
768486003003	dimerization interface [polypeptide binding]; other site
768486003004	domain crossover interface; other site
768486003005	redox-dependent activation switch; other site
768486003006	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
768486003007	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
768486003008	FMN binding site [chemical binding]; other site
768486003009	active site
768486003010	catalytic residues [active]
768486003011	substrate binding site [chemical binding]; other site
768486003012	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
768486003013	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
768486003014	dimer interface [polypeptide binding]; other site
768486003015	putative anticodon binding site; other site
768486003016	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
768486003017	motif 1; other site
768486003018	active site
768486003019	motif 2; other site
768486003020	motif 3; other site
768486003021	S-adenosylmethionine synthetase; Validated; Region: PRK05250
768486003022	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
768486003023	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
768486003024	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
768486003025	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486003026	putative substrate translocation pore; other site
768486003027	Major Facilitator Superfamily; Region: MFS_1; pfam07690
768486003028	Predicted esterase [General function prediction only]; Region: COG0627
768486003029	S-formylglutathione hydrolase; Region: PLN02442
768486003030	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
768486003031	tetracycline repressor protein TetR; Provisional; Region: PRK13756
768486003032	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
768486003033	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
768486003034	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
768486003035	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
768486003036	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486003037	Walker A/P-loop; other site
768486003038	ATP binding site [chemical binding]; other site
768486003039	Q-loop/lid; other site
768486003040	ABC transporter signature motif; other site
768486003041	Walker B; other site
768486003042	D-loop; other site
768486003043	H-loop/switch region; other site
768486003044	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
768486003045	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
768486003046	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
768486003047	Walker A/P-loop; other site
768486003048	ATP binding site [chemical binding]; other site
768486003049	Q-loop/lid; other site
768486003050	ABC transporter signature motif; other site
768486003051	Walker B; other site
768486003052	D-loop; other site
768486003053	H-loop/switch region; other site
768486003054	CopC domain; Region: CopC; cl01012
768486003055	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
768486003056	Cna protein B-type domain; Region: Cna_B; pfam05738
768486003057	Sortase C (SrtC) or subfamily-3 sortases are membrane cysteine transpeptidases found in Gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_C_3; cd05827
768486003058	active site
768486003059	catalytic site [active]
768486003060	Methyltransferase domain; Region: Methyltransf_31; pfam13847
768486003061	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
768486003062	Putative rRNA methylase; Region: rRNA_methylase; pfam06962
768486003063	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
768486003064	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
768486003065	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
768486003066	active site
768486003067	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
768486003068	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
768486003069	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
768486003070	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
768486003071	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
768486003072	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
768486003073	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
768486003074	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
768486003075	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
768486003076	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
768486003077	HIGH motif; other site
768486003078	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
768486003079	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
768486003080	active site
768486003081	KMSKS motif; other site
768486003082	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
768486003083	tRNA binding surface [nucleotide binding]; other site
768486003084	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
768486003085	active site
768486003086	P-loop; other site
768486003087	phosphorylation site [posttranslational modification]
768486003088	potential frameshift: common BLAST hit: gi|300172920|ref|YP_003772085.1| BglG family transcriptional regulator
768486003089	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
768486003090	methionine cluster; other site
768486003091	active site
768486003092	phosphorylation site [posttranslational modification]
768486003093	metal binding site [ion binding]; metal-binding site
768486003094	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
768486003095	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
768486003096	UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase; Provisional; Region: PRK14022
768486003097	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
768486003098	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
768486003099	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
768486003100	Uncharacterized conserved protein [Function unknown]; Region: COG1284
768486003101	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
768486003102	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
768486003103	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
768486003104	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
768486003105	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
768486003106	RNA binding surface [nucleotide binding]; other site
768486003107	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
768486003108	active site
768486003109	uracil binding [chemical binding]; other site
768486003110	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
768486003111	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
768486003112	active site
768486003113	P-loop; other site
768486003114	phosphorylation site [posttranslational modification]
768486003115	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
768486003116	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
768486003117	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
768486003118	methionine cluster; other site
768486003119	active site
768486003120	phosphorylation site [posttranslational modification]
768486003121	metal binding site [ion binding]; metal-binding site
768486003122	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
768486003123	nucleotide binding site [chemical binding]; other site
768486003124	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
768486003125	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
768486003126	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
768486003127	putative active site [active]
768486003128	WxL domain surface cell wall-binding; Region: WxL; pfam13731
768486003129	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
768486003130	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
768486003131	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
768486003132	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
768486003133	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
768486003134	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486003135	dimer interface [polypeptide binding]; other site
768486003136	conserved gate region; other site
768486003137	ABC-ATPase subunit interface; other site
768486003138	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
768486003139	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486003140	dimer interface [polypeptide binding]; other site
768486003141	conserved gate region; other site
768486003142	putative PBP binding loops; other site
768486003143	ABC-ATPase subunit interface; other site
768486003144	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
768486003145	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
768486003146	Domain of unknown function (DUF3502); Region: DUF3502; pfam12010
768486003147	Protein of unknown function, DUF624; Region: DUF624; cl02369
768486003148	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
768486003149	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
768486003150	Histidine kinase; Region: His_kinase; pfam06580
768486003151	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
768486003152	ATP binding site [chemical binding]; other site
768486003153	Mg2+ binding site [ion binding]; other site
768486003154	G-X-G motif; other site
768486003155	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms]; Region: COG4753
768486003156	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486003157	active site
768486003158	phosphorylation site [posttranslational modification]
768486003159	intermolecular recognition site; other site
768486003160	dimerization interface [polypeptide binding]; other site
768486003161	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
768486003162	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
768486003163	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
768486003164	dimerization interface 3.5A [polypeptide binding]; other site
768486003165	active site
768486003166	Enterocin A Immunity; Region: EntA_Immun; pfam08951
768486003167	methionine sulfoxide reductase A; Provisional; Region: PRK14054
768486003168	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
768486003169	active site
768486003170	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
768486003171	catalytic tetrad [active]
768486003172	Protein of unknown function (DUF1003); Region: DUF1003; pfam06210
768486003173	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
768486003174	active site
768486003175	P-loop; other site
768486003176	phosphorylation site [posttranslational modification]
768486003177	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
768486003178	active site
768486003179	methionine cluster; other site
768486003180	phosphorylation site [posttranslational modification]
768486003181	metal binding site [ion binding]; metal-binding site
768486003182	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
768486003183	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
768486003184	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486003185	Coenzyme A binding pocket [chemical binding]; other site
768486003186	YrhK-like protein; Region: YrhK; pfam14145
768486003187	potential frameshift: common BLAST hit: gi|328956501|ref|YP_004373887.1| putative oxidoreductase
768486003188	Streptococcal 67 kDa myosin-cross-reactive antigen like family; Region: Strep_67kDa_ant; cl17487
768486003189	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
768486003190	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
768486003191	CRISPR/Cas system-associated protein Cas1; Region: Cas1_II; cd09720
768486003192	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09638
768486003193	CRISPR/Cas system-associated protein Csn2; Region: Csn2; cd09758
768486003194	CRISPR type II-A/NMEMI-associated protein Csn2; Region: cas_Csn2; TIGR01866
768486003195	tetramer interface [polypeptide binding]; other site
768486003196	putative DNA binding site [nucleotide binding]; other site
768486003197	Ca binding site [ion binding]; other site
768486003198	Ca binding site [ion binding]; other site
768486003199	Protein of unknown function (DUF1622); Region: DUF1622; pfam07784
768486003200	Protein of unknown function (DUF1622); Region: DUF1622; pfam07784
768486003201	potential frameshift: common BLAST hit: gi|383327657|ref|YP_005353541.1| M protein trans-acting positive regulator
768486003202	M protein trans-acting positive regulator (MGA) HTH domain; Region: HTH_Mga; pfam08280
768486003203	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
768486003204	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
768486003205	catalytic residue [active]
768486003206	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
768486003207	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
768486003208	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
768486003209	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
768486003210	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
768486003211	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
768486003212	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
768486003213	Soluble P-type ATPase [General function prediction only]; Region: COG4087
768486003214	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
768486003215	M protein trans-acting positive regulator (MGA) HTH domain; Region: HTH_Mga; pfam08280
768486003216	Mga helix-turn-helix domain; Region: Mga; pfam05043
768486003217	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
768486003218	Hydrolase of X-linked nucleoside diphosphate N terminal; Region: Nudix_N; pfam12535
768486003219	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_14; cd04672
768486003220	nudix motif; other site
768486003221	MarR family; Region: MarR; pfam01047
768486003222	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
768486003223	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486003224	Coenzyme A binding pocket [chemical binding]; other site
768486003225	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
768486003226	B3/4 domain; Region: B3_4; pfam03483
768486003227	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
768486003228	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
768486003229	active site
768486003230	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
768486003231	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
768486003232	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
768486003233	Ca binding site [ion binding]; other site
768486003234	active site
768486003235	catalytic site [active]
768486003236	LytTr DNA-binding domain; Region: LytTR; smart00850
768486003237	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
768486003238	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
768486003239	MarR family; Region: MarR; pfam01047
768486003240	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
768486003241	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
768486003242	putative active site [active]
768486003243	putative FMN binding site [chemical binding]; other site
768486003244	putative substrate binding site [chemical binding]; other site
768486003245	putative catalytic residue [active]
768486003246	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
768486003247	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
768486003248	potential catalytic triad [active]
768486003249	conserved cys residue [active]
768486003250	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
768486003251	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
768486003252	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
768486003253	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
768486003254	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
768486003255	potential frameshift: common BLAST hit: gi|281491766|ref|YP_003353746.1| trans-acting positive regulator
768486003256	potential frameshift: common BLAST hit: gi|15673228|ref|NP_267402.1| glycerol kinase
768486003257	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
768486003258	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
768486003259	amphipathic channel; other site
768486003260	Asn-Pro-Ala signature motifs; other site
768486003261	MutS domain III; Region: MutS_III; pfam05192
768486003262	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486003263	Walker A/P-loop; other site
768486003264	ATP binding site [chemical binding]; other site
768486003265	Q-loop/lid; other site
768486003266	ABC transporter signature motif; other site
768486003267	Walker B; other site
768486003268	D-loop; other site
768486003269	H-loop/switch region; other site
768486003270	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
768486003271	DsrE/DsrF-like family; Region: DrsE; cl00672
768486003272	Uncharacterized protein YrkD from Bacillus subtilis and related domains; this domain superfamily was previously known as part of DUF156; Region: BsYrkD-like_DUF156; cd10155
768486003273	putative homodimer interface [polypeptide binding]; other site
768486003274	putative homotetramer interface [polypeptide binding]; other site
768486003275	putative metal binding site [ion binding]; other site
768486003276	putative homodimer-homodimer interface [polypeptide binding]; other site
768486003277	putative allosteric switch controlling residues; other site
768486003278	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
768486003279	active site residue [active]
768486003280	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
768486003281	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
768486003282	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
768486003283	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
768486003284	Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar...; Region: RHOD_Pyr_redox; cd01524
768486003285	active site residue [active]
768486003286	Part of AAA domain; Region: AAA_19; pfam13245
768486003287	Family description; Region: UvrD_C_2; pfam13538
768486003288	potential frameshift: common BLAST hit: gi|15672858|ref|NP_267032.1| glycosyl transferase
768486003289	Cellulose synthase-like protein; Region: PLN02893
768486003290	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
768486003291	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
768486003292	DXD motif; other site
768486003293	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
768486003294	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
768486003295	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
768486003296	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
768486003297	tetramerization interface [polypeptide binding]; other site
768486003298	NAD(P) binding site [chemical binding]; other site
768486003299	catalytic residues [active]
768486003300	glycosyltransferase, TIGR04182 family; Region: glyco_TIGR04182
768486003301	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
768486003302	Ligand binding site; other site
768486003303	Putative Catalytic site; other site
768486003304	DXD motif; other site
768486003305	Predicted small secreted protein [Function unknown]; Region: COG5584
768486003306	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
768486003307	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
768486003308	oligomer interface [polypeptide binding]; other site
768486003309	active site
768486003310	metal binding site [ion binding]; metal-binding site
768486003311	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
768486003312	catalytic residues [active]
768486003313	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
768486003314	Ligand Binding Site [chemical binding]; other site
768486003315	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
768486003316	putative tRNA-binding site [nucleotide binding]; other site
768486003317	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
768486003318	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
768486003319	protein binding site [polypeptide binding]; other site
768486003320	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
768486003321	GIY-YIG domain of uncharacterized proteins from bacteria and their eukaryotic homologs; Region: GIY-YIG_COG3680; cd10440
768486003322	GIY-YIG motif/motif A; other site
768486003323	putative active site [active]
768486003324	putative metal binding site [ion binding]; other site
768486003325	6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein; Region: PTPS_related; pfam10131
768486003326	6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein; Region: PTPS_related; pfam10131
768486003327	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
768486003328	active site
768486003329	P-loop; other site
768486003330	phosphorylation site [posttranslational modification]
768486003331	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
768486003332	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
768486003333	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
768486003334	methionine cluster; other site
768486003335	active site
768486003336	phosphorylation site [posttranslational modification]
768486003337	metal binding site [ion binding]; metal-binding site
768486003338	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
768486003339	beta-galactosidase; Region: BGL; TIGR03356
768486003340	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
768486003341	HTH domain; Region: HTH_11; pfam08279
768486003342	Mga helix-turn-helix domain; Region: Mga; pfam05043
768486003343	PRD domain; Region: PRD; pfam00874
768486003344	PRD domain; Region: PRD; pfam00874
768486003345	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Region: PTS_EIIA_2; pfam00359
768486003346	active site
768486003347	phosphorylation site [posttranslational modification]
768486003348	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
768486003349	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
768486003350	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
768486003351	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
768486003352	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
768486003353	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
768486003354	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
768486003355	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
768486003356	DNA-binding site [nucleotide binding]; DNA binding site
768486003357	Transcriptional regulators [Transcription]; Region: PurR; COG1609
768486003358	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
768486003359	ligand binding site [chemical binding]; other site
768486003360	dimerization interface [polypeptide binding]; other site
768486003361	Uncharacterized conserved protein [Function unknown]; Region: COG3538
768486003362	Protein of unknown function (DUF1237); Region: DUF1237; pfam06824
768486003363	Alpha-mannosidase [Carbohydrate transport and metabolism]; Region: AMS1; COG0383
768486003364	N-terminal catalytic domain of SPGH38, a putative alpha-mannosidase of Streptococcus pyogenes, and its prokaryotic homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_SpGH38_like; cd10814
768486003365	active site
768486003366	metal binding site [ion binding]; metal-binding site
768486003367	homodimer interface [polypeptide binding]; other site
768486003368	catalytic site [active]
768486003369	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
768486003370	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
768486003371	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
768486003372	nucleotide binding site [chemical binding]; other site
768486003373	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
768486003374	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
768486003375	active site
768486003376	Transglycosylase; Region: Transgly; pfam00912
768486003377	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
768486003378	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
768486003379	hypothetical protein; Provisional; Region: PRK13676
768486003380	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
768486003381	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
768486003382	active site
768486003383	metal binding site [ion binding]; metal-binding site
768486003384	DNA binding site [nucleotide binding]
768486003385	AAA domain; Region: AAA_23; pfam13476
768486003386	P-loop containing region of AAA domain; Region: AAA_29; cl17516
768486003387	3'-5' exoribonuclease YhaM; Provisional; Region: PRK13480
768486003388	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
768486003389	generic binding surface II; other site
768486003390	generic binding surface I; other site
768486003391	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
768486003392	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
768486003393	Zn2+ binding site [ion binding]; other site
768486003394	Mg2+ binding site [ion binding]; other site
768486003395	foldase protein PrsA; Reviewed; Region: prsA; PRK01326
768486003396	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
768486003397	YtxH-like protein; Region: YtxH; pfam12732
768486003398	HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277
768486003399	HIT family signature motif; other site
768486003400	catalytic residue [active]
768486003401	potential frameshift: common BLAST hit: gi|29375285|ref|NP_814438.1| ABC transporter ATP-binding protein
768486003402	Bacterial ABC transporter protein EcsB; Region: EcsB; pfam05975
768486003403	Phosphotransferase enzyme family; Region: APH; pfam01636
768486003404	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
768486003405	active site
768486003406	substrate binding site [chemical binding]; other site
768486003407	ATP binding site [chemical binding]; other site
768486003408	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486003409	S-adenosylmethionine binding site [chemical binding]; other site
768486003410	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
768486003411	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
768486003412	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
768486003413	active site
768486003414	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
768486003415	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
768486003416	Walker A motif; other site
768486003417	ATP binding site [chemical binding]; other site
768486003418	Walker B motif; other site
768486003419	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
768486003420	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
768486003421	Competence protein ComGC [Intracellular trafficking and secretion]; Region: ComGC; COG4537
768486003422	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
768486003423	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
768486003424	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
768486003425	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486003426	S-adenosylmethionine binding site [chemical binding]; other site
768486003427	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
768486003428	propionate/acetate kinase; Provisional; Region: PRK12379
768486003429	nucleotide binding site [chemical binding]; other site
768486003430	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
768486003431	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
768486003432	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
768486003433	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
768486003434	Ligand Binding Site [chemical binding]; other site
768486003435	recombination factor protein RarA; Reviewed; Region: PRK13342
768486003436	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486003437	Walker A motif; other site
768486003438	ATP binding site [chemical binding]; other site
768486003439	Walker B motif; other site
768486003440	arginine finger; other site
768486003441	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
768486003442	DinB superfamily; Region: DinB_2; pfam12867
768486003443	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
768486003444	active site
768486003445	DNA binding site [nucleotide binding]
768486003446	Protein of unknown function (DUF3013); Region: DUF3013; pfam11217
768486003447	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
768486003448	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486003449	S-adenosylmethionine binding site [chemical binding]; other site
768486003450	Ribosomal protein L11 methylase [Translation, ribosomal structure and biogenesis]; Region: PrmA; COG2264
768486003451	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
768486003452	RNA methyltransferase, RsmE family; Region: TIGR00046
768486003453	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
768486003454	HD domain; Region: HD_4; pfam13328
768486003455	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
768486003456	synthetase active site [active]
768486003457	NTP binding site [chemical binding]; other site
768486003458	metal binding site [ion binding]; metal-binding site
768486003459	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
768486003460	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
768486003461	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
768486003462	putative active site [active]
768486003463	dimerization interface [polypeptide binding]; other site
768486003464	putative tRNAtyr binding site [nucleotide binding]; other site
768486003465	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
768486003466	Cytochrome P450; Region: p450; cl12078
768486003467	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
768486003468	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
768486003469	active site
768486003470	catalytic tetrad [active]
768486003471	histidyl-tRNA synthetase; Region: hisS; TIGR00442
768486003472	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
768486003473	dimer interface [polypeptide binding]; other site
768486003474	motif 1; other site
768486003475	active site
768486003476	motif 2; other site
768486003477	motif 3; other site
768486003478	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
768486003479	anticodon binding site; other site
768486003480	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
768486003481	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
768486003482	dimer interface [polypeptide binding]; other site
768486003483	anticodon binding site; other site
768486003484	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
768486003485	homodimer interface [polypeptide binding]; other site
768486003486	motif 1; other site
768486003487	active site
768486003488	motif 2; other site
768486003489	GAD domain; Region: GAD; pfam02938
768486003490	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
768486003491	motif 3; other site
768486003492	Uncharacterized conserved protein [Function unknown]; Region: COG1284
768486003493	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
768486003494	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
768486003495	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
768486003496	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
768486003497	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
768486003498	catalytic triad [active]
768486003499	catalytic triad [active]
768486003500	oxyanion hole [active]
768486003501	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
768486003502	GIY-YIG motif/motif A; other site
768486003503	putative active site [active]
768486003504	putative metal binding site [ion binding]; other site
768486003505	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
768486003506	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486003507	S-adenosylmethionine binding site [chemical binding]; other site
768486003508	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
768486003509	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
768486003510	putative acyl-acceptor binding pocket; other site
768486003511	potential frameshift: common BLAST hit: gi|389869611|ref|YP_006377034.1| exonuclease SbcD
768486003512	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
768486003513	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
768486003514	active site
768486003515	metal binding site [ion binding]; metal-binding site
768486003516	DNA binding site [nucleotide binding]
768486003517	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
768486003518	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
768486003519	AAA domain; Region: AAA_23; pfam13476
768486003520	Walker A/P-loop; other site
768486003521	ATP binding site [chemical binding]; other site
768486003522	Q-loop/lid; other site
768486003523	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486003524	ABC transporter signature motif; other site
768486003525	Walker B; other site
768486003526	D-loop; other site
768486003527	H-loop/switch region; other site
768486003528	SWIM zinc finger; Region: SWIM; pfam04434
768486003529	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
768486003530	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
768486003531	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
768486003532	ATP binding site [chemical binding]; other site
768486003533	putative Mg++ binding site [ion binding]; other site
768486003534	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
768486003535	nucleotide binding region [chemical binding]; other site
768486003536	ATP-binding site [chemical binding]; other site
768486003537	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
768486003538	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486003539	motif II; other site
768486003540	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
768486003541	ArsC family; Region: ArsC; pfam03960
768486003542	putative catalytic residues [active]
768486003543	thiol/disulfide switch; other site
768486003544	Negative regulator of genetic competence (MecA); Region: MecA; pfam05389
768486003545	Competence protein CoiA-like family; Region: CoiA; pfam06054
768486003546	Oligoendopeptidase F [Amino acid transport and metabolism]; Region: COG1164
768486003547	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
768486003548	active site
768486003549	Zn binding site [ion binding]; other site
768486003550	galactokinase; Provisional; Region: PRK05322
768486003551	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
768486003552	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
768486003553	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
768486003554	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
768486003555	active site
768486003556	catalytic residues [active]
768486003557	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
768486003558	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
768486003559	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
768486003560	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
768486003561	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
768486003562	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
768486003563	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
768486003564	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cl00107
768486003565	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
768486003566	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
768486003567	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
768486003568	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
768486003569	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
768486003570	ABC-ATPase subunit  interface; other site
768486003571	dimer interface [polypeptide binding]; other site
768486003572	putative PBP binding regions; other site
768486003573	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
768486003574	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
768486003575	metal binding site [ion binding]; metal-binding site
768486003576	epoxyqueuosine reductase; Region: TIGR00276
768486003577	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
768486003578	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
768486003579	glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352
768486003580	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486003581	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
768486003582	putative substrate translocation pore; other site
768486003583	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
768486003584	Arginine repressor [Transcription]; Region: ArgR; COG1438
768486003585	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
768486003586	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
768486003587	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
768486003588	active site
768486003589	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
768486003590	substrate binding site [chemical binding]; other site
768486003591	metal binding site [ion binding]; metal-binding site
768486003592	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
768486003593	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
768486003594	dimanganese center [ion binding]; other site
768486003595	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
768486003596	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
768486003597	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
768486003598	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486003599	dimer interface [polypeptide binding]; other site
768486003600	conserved gate region; other site
768486003601	putative PBP binding loops; other site
768486003602	ABC-ATPase subunit interface; other site
768486003603	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
768486003604	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486003605	dimer interface [polypeptide binding]; other site
768486003606	conserved gate region; other site
768486003607	putative PBP binding loops; other site
768486003608	ABC-ATPase subunit interface; other site
768486003609	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
768486003610	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486003611	active site
768486003612	phosphorylation site [posttranslational modification]
768486003613	intermolecular recognition site; other site
768486003614	dimerization interface [polypeptide binding]; other site
768486003615	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
768486003616	DNA binding site [nucleotide binding]
768486003617	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
768486003618	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
768486003619	dimer interface [polypeptide binding]; other site
768486003620	phosphorylation site [posttranslational modification]
768486003621	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
768486003622	ATP binding site [chemical binding]; other site
768486003623	Mg2+ binding site [ion binding]; other site
768486003624	G-X-G motif; other site
768486003625	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
768486003626	amino acid transporter; Region: 2A0306; TIGR00909
768486003627	Spore germination protein; Region: Spore_permease; cl17796
768486003628	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
768486003629	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
768486003630	5-bromo-4-chloroindolyl phosphate hydrolysis protein; Region: Halogen_Hydrol; pfam10112
768486003631	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
768486003632	dimer interface [polypeptide binding]; other site
768486003633	ADP-ribose binding site [chemical binding]; other site
768486003634	active site
768486003635	nudix motif; other site
768486003636	metal binding site [ion binding]; metal-binding site
768486003637	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
768486003638	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
768486003639	Isochorismatase family; Region: Isochorismatase; pfam00857
768486003640	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
768486003641	catalytic triad [active]
768486003642	conserved cis-peptide bond; other site
768486003643	BioY family; Region: BioY; pfam02632
768486003644	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
768486003645	AAA domain; Region: AAA_26; pfam13500
768486003646	biotin synthase; Region: bioB; TIGR00433
768486003647	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
768486003648	FeS/SAM binding site; other site
768486003649	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
768486003650	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
768486003651	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
768486003652	active site
768486003653	Zn binding site [ion binding]; other site
768486003654	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
768486003655	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK02458
768486003656	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
768486003657	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
768486003658	active site
768486003659	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
768486003660	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
768486003661	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
768486003662	catalytic residue [active]
768486003663	Putative amino acid metabolism; Region: DUF1831; pfam08866
768486003664	Aquifex aeolicus AQ1575 and related proteins, metallophosphatase domain; Region: MPP_AQ1575; cd07390
768486003665	putative active site [active]
768486003666	putative metal binding site [ion binding]; other site
768486003667	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
768486003668	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
768486003669	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
768486003670	transaminase; Validated; Region: PRK07324
768486003671	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
768486003672	pyridoxal 5'-phosphate binding site [chemical binding]; other site
768486003673	homodimer interface [polypeptide binding]; other site
768486003674	catalytic residue [active]
768486003675	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486003676	Major Facilitator Superfamily; Region: MFS_1; pfam07690
768486003677	putative substrate translocation pore; other site
768486003678	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
768486003679	WHG domain; Region: WHG; pfam13305
768486003680	Protein of unknown function (DUF1033); Region: DUF1033; pfam06279
768486003681	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
768486003682	DNA topoisomerase III; Provisional; Region: PRK07726
768486003683	active site
768486003684	putative metal-binding site [ion binding]; other site
768486003685	putative interdomain interaction site [polypeptide binding]; other site
768486003686	putative nucleotide binding site [chemical binding]; other site
768486003687	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
768486003688	domain I; other site
768486003689	DNA binding groove [nucleotide binding]
768486003690	phosphate binding site [ion binding]; other site
768486003691	domain II; other site
768486003692	domain III; other site
768486003693	nucleotide binding site [chemical binding]; other site
768486003694	catalytic site [active]
768486003695	domain IV; other site
768486003696	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
768486003697	This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and Clostridium sticklandii PrdX) and eukaryotic (Plasmodium falciparum N-terminal ProRS editing domain) sequences. The C. sticklandii PrdX protein, a homolog of the...; Region: PrdX_deacylase; cd04335
768486003698	putative deacylase active site [active]
768486003699	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486003700	dimer interface [polypeptide binding]; other site
768486003701	conserved gate region; other site
768486003702	putative PBP binding loops; other site
768486003703	ABC-ATPase subunit interface; other site
768486003704	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
768486003705	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486003706	Walker A/P-loop; other site
768486003707	ATP binding site [chemical binding]; other site
768486003708	Q-loop/lid; other site
768486003709	ABC transporter signature motif; other site
768486003710	Walker B; other site
768486003711	D-loop; other site
768486003712	H-loop/switch region; other site
768486003713	potential frameshift: common BLAST hit: gi|389869459|ref|YP_006376882.1| amino acid ABC superfamily ATP binding cassette transporter
768486003714	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
768486003715	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
768486003716	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
768486003717	substrate binding pocket [chemical binding]; other site
768486003718	membrane-bound complex binding site; other site
768486003719	hinge residues; other site
768486003720	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
768486003721	beta-galactosidase; Region: BGL; TIGR03356
768486003722	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
768486003723	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
768486003724	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
768486003725	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14455
768486003726	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
768486003727	FeS/SAM binding site; other site
768486003728	putative acetyltransferase; Provisional; Region: PRK03624
768486003729	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486003730	Coenzyme A binding pocket [chemical binding]; other site
768486003731	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
768486003732	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
768486003733	peptide binding site [polypeptide binding]; other site
768486003734	Domain of unknown function (DUF3899); Region: DUF3899; pfam13038
768486003735	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
768486003736	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486003737	dimer interface [polypeptide binding]; other site
768486003738	conserved gate region; other site
768486003739	putative PBP binding loops; other site
768486003740	ABC-ATPase subunit interface; other site
768486003741	dipeptide transporter; Provisional; Region: PRK10913
768486003742	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
768486003743	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486003744	dimer interface [polypeptide binding]; other site
768486003745	conserved gate region; other site
768486003746	putative PBP binding loops; other site
768486003747	ABC-ATPase subunit interface; other site
768486003748	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
768486003749	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
768486003750	Walker A/P-loop; other site
768486003751	ATP binding site [chemical binding]; other site
768486003752	Q-loop/lid; other site
768486003753	ABC transporter signature motif; other site
768486003754	Walker B; other site
768486003755	D-loop; other site
768486003756	H-loop/switch region; other site
768486003757	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
768486003758	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
768486003759	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
768486003760	Walker A/P-loop; other site
768486003761	ATP binding site [chemical binding]; other site
768486003762	Q-loop/lid; other site
768486003763	ABC transporter signature motif; other site
768486003764	Walker B; other site
768486003765	D-loop; other site
768486003766	H-loop/switch region; other site
768486003767	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
768486003768	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
768486003769	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
768486003770	Probable transposase; Region: OrfB_IS605; pfam01385
768486003771	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
768486003772	nudix motif; other site
768486003773	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
768486003774	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
768486003775	active site
768486003776	HIGH motif; other site
768486003777	KMSKS motif; other site
768486003778	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
768486003779	tRNA binding surface [nucleotide binding]; other site
768486003780	anticodon binding site; other site
768486003781	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
768486003782	dimer interface [polypeptide binding]; other site
768486003783	putative tRNA-binding site [nucleotide binding]; other site
768486003784	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
768486003785	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
768486003786	KAP family P-loop domain; Region: KAP_NTPase; pfam07693
768486003787	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
768486003788	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486003789	non-specific DNA binding site [nucleotide binding]; other site
768486003790	salt bridge; other site
768486003791	sequence-specific DNA binding site [nucleotide binding]; other site
768486003792	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
768486003793	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
768486003794	catalytic motif [active]
768486003795	Zn binding site [ion binding]; other site
768486003796	RibD C-terminal domain; Region: RibD_C; cl17279
768486003797	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
768486003798	Lumazine binding domain; Region: Lum_binding; pfam00677
768486003799	Lumazine binding domain; Region: Lum_binding; pfam00677
768486003800	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
768486003801	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
768486003802	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
768486003803	dimerization interface [polypeptide binding]; other site
768486003804	active site
768486003805	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
768486003806	homopentamer interface [polypeptide binding]; other site
768486003807	active site
768486003808	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
768486003809	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
768486003810	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
768486003811	active site
768486003812	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
768486003813	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
768486003814	putative active site [active]
768486003815	putative metal binding site [ion binding]; other site
768486003816	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
768486003817	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
768486003818	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486003819	S-adenosylmethionine binding site [chemical binding]; other site
768486003820	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
768486003821	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
768486003822	Walker A/P-loop; other site
768486003823	ATP binding site [chemical binding]; other site
768486003824	Q-loop/lid; other site
768486003825	ABC transporter signature motif; other site
768486003826	Walker B; other site
768486003827	D-loop; other site
768486003828	H-loop/switch region; other site
768486003829	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
768486003830	active site
768486003831	dimer interfaces [polypeptide binding]; other site
768486003832	catalytic residues [active]
768486003833	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; cl17272
768486003834	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
768486003835	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
768486003836	catalytic residues [active]
768486003837	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486003838	non-specific DNA binding site [nucleotide binding]; other site
768486003839	salt bridge; other site
768486003840	sequence-specific DNA binding site [nucleotide binding]; other site
768486003841	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
768486003842	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
768486003843	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
768486003844	Walker A/P-loop; other site
768486003845	ATP binding site [chemical binding]; other site
768486003846	Q-loop/lid; other site
768486003847	ABC transporter signature motif; other site
768486003848	Walker B; other site
768486003849	D-loop; other site
768486003850	H-loop/switch region; other site
768486003851	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
768486003852	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
768486003853	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486003854	Walker A/P-loop; other site
768486003855	ATP binding site [chemical binding]; other site
768486003856	Q-loop/lid; other site
768486003857	ABC transporter signature motif; other site
768486003858	Walker B; other site
768486003859	D-loop; other site
768486003860	H-loop/switch region; other site
768486003861	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
768486003862	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486003863	Walker A motif; other site
768486003864	ATP binding site [chemical binding]; other site
768486003865	Walker B motif; other site
768486003866	arginine finger; other site
768486003867	Transcriptional antiterminator [Transcription]; Region: COG3933
768486003868	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
768486003869	active pocket/dimerization site; other site
768486003870	active site
768486003871	phosphorylation site [posttranslational modification]
768486003872	PRD domain; Region: PRD; pfam00874
768486003873	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
768486003874	active pocket/dimerization site; other site
768486003875	active site
768486003876	phosphorylation site [posttranslational modification]
768486003877	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
768486003878	active site
768486003879	phosphorylation site [posttranslational modification]
768486003880	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
768486003881	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
768486003882	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
768486003883	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
768486003884	dimer interface [polypeptide binding]; other site
768486003885	active site
768486003886	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
768486003887	dimer interface [polypeptide binding]; other site
768486003888	active site
768486003889	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
768486003890	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
768486003891	putative active site [active]
768486003892	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
768486003893	Chitin binding domain; Region: Chitin_bind_3; pfam03067
768486003894	Chitin binding domain; Region: Chitin_bind_3; pfam03067
768486003895	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486003896	non-specific DNA binding site [nucleotide binding]; other site
768486003897	salt bridge; other site
768486003898	sequence-specific DNA binding site [nucleotide binding]; other site
768486003899	transcriptional activator, Rgg/GadR/MutR family, C-terminal domain; Region: RGG_Cterm; TIGR01716
768486003900	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
768486003901	Glycosyl hydrolases family 18; Region: Glyco_hydro_18; pfam00704
768486003902	active site
768486003903	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
768486003904	Interdomain contacts; other site
768486003905	Cytokine receptor motif; other site
768486003906	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
768486003907	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
768486003908	Interdomain contacts; other site
768486003909	Cytokine receptor motif; other site
768486003910	chitin-binding domain of Chi A1-like proteins; Region: ChiA1_BD; cd12214
768486003911	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
768486003912	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
768486003913	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
768486003914	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
768486003915	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
768486003916	active site
768486003917	tetramer interface; other site
768486003918	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
768486003919	Predicted membrane protein [Function unknown]; Region: COG1288; cl17886
768486003920	hypothetical protein; Provisional; Region: PRK11588
768486003921	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
768486003922	isoaspartyl dipeptidase; Provisional; Region: PRK10657
768486003923	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
768486003924	active site
768486003925	CsbD-like; Region: CsbD; cl17424
768486003926	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
768486003927	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
768486003928	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
768486003929	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cl00022
768486003930	putative deacylase active site [active]
768486003931	metal-dependent hydrolase; Provisional; Region: PRK00685
768486003932	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
768486003933	Predicted transcriptional regulator containing CBS domains [Transcription]; Region: COG4109
768486003934	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
768486003935	DNA-binding site [nucleotide binding]; DNA binding site
768486003936	DRTGG domain; Region: DRTGG; pfam07085
768486003937	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with a DRTGG domain upstream. The function of the DRTGG domain, named after its conserved residues, is unknown. CBS is a small domain originally...; Region: CBS_pair_DRTGG_assoc; cd04596
768486003938	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
768486003939	active site 2 [active]
768486003940	active site 1 [active]
768486003941	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
768486003942	DHH family; Region: DHH; pfam01368
768486003943	DHHA1 domain; Region: DHHA1; pfam02272
768486003944	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
768486003945	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
768486003946	PhnA protein; Region: PhnA; pfam03831
768486003947	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
768486003948	potential frameshift: common BLAST hit: gi|383329554|ref|YP_005355438.1| M protein trans-acting positive regulator
768486003949	Mga helix-turn-helix domain; Region: Mga; pfam05043
768486003950	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
768486003951	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
768486003952	nucleoside/Zn binding site; other site
768486003953	dimer interface [polypeptide binding]; other site
768486003954	catalytic motif [active]
768486003955	Holin family; Region: Phage_holin_4; cl01989
768486003956	Bacteriophage peptidoglycan hydrolase; Region: Amidase_5; pfam05382
768486003957	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
768486003958	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
768486003959	active site
768486003960	metal binding site [ion binding]; metal-binding site
768486003961	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
768486003962	Protein of unknown function (DUF1027); Region: DUF1027; pfam06265
768486003963	HAD-superfamily subfamily IIA hydrolase, TIGR01457; Region: HAD-SF-IIA-hyp2
768486003964	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486003965	active site
768486003966	motif I; other site
768486003967	motif II; other site
768486003968	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486003969	Protein of unknown function (DUF1461); Region: DUF1461; pfam07314
768486003970	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
768486003971	tetramer interfaces [polypeptide binding]; other site
768486003972	binuclear metal-binding site [ion binding]; other site
768486003973	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
768486003974	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
768486003975	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
768486003976	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
768486003977	active site
768486003978	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
768486003979	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
768486003980	pyridoxal 5'-phosphate binding site [chemical binding]; other site
768486003981	homodimer interface [polypeptide binding]; other site
768486003982	catalytic residue [active]
768486003983	Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis]; Region: VacB; COG1098
768486003984	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
768486003985	RNA binding site [nucleotide binding]; other site
768486003986	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4918
768486003987	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
768486003988	trimer interface [polypeptide binding]; other site
768486003989	active site
768486003990	G bulge; other site
768486003991	Phosphotransferase enzyme family; Region: APH; pfam01636
768486003992	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
768486003993	active site
768486003994	ATP binding site [chemical binding]; other site
768486003995	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
768486003996	substrate binding site [chemical binding]; other site
768486003997	Acyl-ACP thioesterase; Region: Acyl-ACP_TE; pfam01643
768486003998	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
768486003999	active site
768486004000	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
768486004001	active site
768486004002	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
768486004003	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
768486004004	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
768486004005	active site
768486004006	homotetramer interface [polypeptide binding]; other site
768486004007	homodimer interface [polypeptide binding]; other site
768486004008	Protein of unknown function DUF72; Region: DUF72; pfam01904
768486004009	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486004010	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
768486004011	active site
768486004012	motif I; other site
768486004013	motif II; other site
768486004014	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486004015	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4696
768486004016	metal binding site [ion binding]; metal-binding site
768486004017	Septation ring formation regulator, EzrA; Region: EzrA; pfam06160
768486004018	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
768486004019	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
768486004020	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
768486004021	catalytic residue [active]
768486004022	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
768486004023	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
768486004024	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
768486004025	Ligand Binding Site [chemical binding]; other site
768486004026	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
768486004027	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
768486004028	CoA binding domain; Region: CoA_binding; pfam02629
768486004029	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
768486004030	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
768486004031	active site
768486004032	HIGH motif; other site
768486004033	nucleotide binding site [chemical binding]; other site
768486004034	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
768486004035	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
768486004036	active site
768486004037	KMSKS motif; other site
768486004038	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
768486004039	tRNA binding surface [nucleotide binding]; other site
768486004040	anticodon binding site; other site
768486004041	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
768486004042	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
768486004043	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
768486004044	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
768486004045	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
768486004046	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486004047	motif II; other site
768486004048	hypothetical protein; Reviewed; Region: PRK00024
768486004049	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
768486004050	MPN+ (JAMM) motif; other site
768486004051	Zinc-binding site [ion binding]; other site
768486004052	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
768486004053	DNA-binding site [nucleotide binding]; DNA binding site
768486004054	RNA-binding motif; other site
768486004055	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
768486004056	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
768486004057	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
768486004058	Protein of unknown function (DUF1447); Region: DUF1447; pfam07288
768486004059	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
768486004060	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
768486004061	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486004062	Walker A/P-loop; other site
768486004063	ATP binding site [chemical binding]; other site
768486004064	Q-loop/lid; other site
768486004065	ABC transporter signature motif; other site
768486004066	Walker B; other site
768486004067	D-loop; other site
768486004068	H-loop/switch region; other site
768486004069	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
768486004070	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
768486004071	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
768486004072	Walker A/P-loop; other site
768486004073	ATP binding site [chemical binding]; other site
768486004074	Q-loop/lid; other site
768486004075	ABC transporter signature motif; other site
768486004076	Walker B; other site
768486004077	D-loop; other site
768486004078	H-loop/switch region; other site
768486004079	legume lectins; Region: lectin_L-type; cl14058
768486004080	homotetramer interaction site [polypeptide binding]; other site
768486004081	homodimer interaction site [polypeptide binding]; other site
768486004082	carbohydrate binding site [chemical binding]; other site
768486004083	metal binding site [ion binding]; metal-binding site
768486004084	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
768486004085	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
768486004086	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
768486004087	trimer interface [polypeptide binding]; other site
768486004088	putative metal binding site [ion binding]; other site
768486004089	Clp protease; Region: CLP_protease; pfam00574
768486004090	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
768486004091	oligomer interface [polypeptide binding]; other site
768486004092	active site residues [active]
768486004093	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
768486004094	Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins; Region: GDPD_TtGDE_like; cd08563
768486004095	active site
768486004096	catalytic site [active]
768486004097	metal binding site [ion binding]; metal-binding site
768486004098	dimer interface [polypeptide binding]; other site
768486004099	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
768486004100	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
768486004101	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
768486004102	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
768486004103	HflX GTPase family; Region: HflX; cd01878
768486004104	G1 box; other site
768486004105	GTP/Mg2+ binding site [chemical binding]; other site
768486004106	Switch I region; other site
768486004107	G2 box; other site
768486004108	G3 box; other site
768486004109	Switch II region; other site
768486004110	G4 box; other site
768486004111	G5 box; other site
768486004112	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
768486004113	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
768486004114	DNA binding residues [nucleotide binding]
768486004115	putative dimer interface [polypeptide binding]; other site
768486004116	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
768486004117	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
768486004118	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
768486004119	CTP synthetase; Validated; Region: pyrG; PRK05380
768486004120	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
768486004121	Catalytic site [active]
768486004122	active site
768486004123	UTP binding site [chemical binding]; other site
768486004124	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
768486004125	active site
768486004126	putative oxyanion hole; other site
768486004127	catalytic triad [active]
768486004128	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
768486004129	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
768486004130	intersubunit interface [polypeptide binding]; other site
768486004131	active site
768486004132	zinc binding site [ion binding]; other site
768486004133	Na+ binding site [ion binding]; other site
768486004134	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
768486004135	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
768486004136	hinge; other site
768486004137	active site
768486004138	transcription termination factor Rho; Provisional; Region: rho; PRK09376
768486004139	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
768486004140	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
768486004141	RNA binding site [nucleotide binding]; other site
768486004142	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
768486004143	Walker A motif; other site
768486004144	ATP binding site [chemical binding]; other site
768486004145	Walker B motif; other site
768486004146	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
768486004147	4-hydroxyphenylpyruvate dioxygenase; Region: PLN02875
768486004148	Peptidase M60-like family; Region: M60-like; pfam13402
768486004149	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
768486004150	aromatic chitin/cellulose binding site residues [chemical binding]; other site
768486004151	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
768486004152	active site
768486004153	phosphorylation site [posttranslational modification]
768486004154	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
768486004155	active site
768486004156	P-loop; other site
768486004157	phosphorylation site [posttranslational modification]
768486004158	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
768486004159	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
768486004160	intersubunit interface [polypeptide binding]; other site
768486004161	active site
768486004162	zinc binding site [ion binding]; other site
768486004163	Na+ binding site [ion binding]; other site
768486004164	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
768486004165	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
768486004166	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
768486004167	Endo-beta-N-acetylglucosaminidase D [Carbohydrate transport and metabolism]; Region: COG4724
768486004168	Endo-beta-N-acetylglucosaminidase (ENGase) hydrolyzes the N-N'-diacetylchitobiosyl core of N-glycosylproteins.  The beta-1,4-glycosyl bond located between two N-acetylglucosamine residues is hydrolyzed such that N-acetylglucosamine 1 remains with...; Region: GH85_ENGase; cd06547
768486004169	putative active site [active]
768486004170	FOG: PKD repeat [General function prediction only]; Region: COG3291
768486004171	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
768486004172	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
768486004173	sugar binding site [chemical binding]; other site
768486004174	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486004175	Major Facilitator Superfamily; Region: MFS_1; pfam07690
768486004176	putative substrate translocation pore; other site
768486004177	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
768486004178	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
768486004179	ligand binding site [chemical binding]; other site
768486004180	flexible hinge region; other site
768486004181	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
768486004182	non-specific DNA interactions [nucleotide binding]; other site
768486004183	DNA binding site [nucleotide binding]
768486004184	sequence specific DNA binding site [nucleotide binding]; other site
768486004185	putative cAMP binding site [chemical binding]; other site
768486004186	Repair protein; Region: Repair_PSII; pfam04536
768486004187	Membrane protease subunit, stomatin/prohibitin family [Amino acid    transport and metabolism]; Region: COG4260
768486004188	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_5; cd03408
768486004189	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
768486004190	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
768486004191	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486004192	Walker A motif; other site
768486004193	ATP binding site [chemical binding]; other site
768486004194	Walker B motif; other site
768486004195	arginine finger; other site
768486004196	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
768486004197	hypothetical protein; Validated; Region: PRK00153
768486004198	recombination protein RecR; Reviewed; Region: recR; PRK00076
768486004199	RecR protein; Region: RecR; pfam02132
768486004200	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
768486004201	putative active site [active]
768486004202	putative metal-binding site [ion binding]; other site
768486004203	tetramer interface [polypeptide binding]; other site
768486004204	thymidylate kinase; Validated; Region: tmk; PRK00698
768486004205	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
768486004206	TMP-binding site; other site
768486004207	ATP-binding site [chemical binding]; other site
768486004208	Protein of unknown function (DUF970); Region: DUF970; cl17525
768486004209	DNA polymerase III subunit delta'; Validated; Region: PRK08058
768486004210	DNA polymerase III subunit delta'; Validated; Region: PRK08485
768486004211	Uncharacterized homolog of PSP1 [Function unknown]; Region: COG1774
768486004212	Protein of unknown function (DUF972); Region: DUF972; pfam06156
768486004213	Predicted methyltransferases [General function prediction only]; Region: COG0313
768486004214	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
768486004215	putative SAM binding site [chemical binding]; other site
768486004216	putative homodimer interface [polypeptide binding]; other site
768486004217	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
768486004218	catalytic residues [active]
768486004219	Predicted permeases [General function prediction only]; Region: COG0701
768486004220	Predicted membrane protein [Function unknown]; Region: COG3689
768486004221	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
768486004222	Uncharacterized conserved protein [Function unknown]; Region: COG2966
768486004223	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
768486004224	potential protein location (hypothetical protein EHR_08035 [Enterococcus hirae ATCC 9790]) that overlaps RNA (tRNA-G)
768486004225	potential frameshift: common BLAST hit: gi|258539355|ref|YP_003173854.1| DNA-entry nuclease
768486004226	hypothetical protein; Provisional; Region: PRK05473
768486004227	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
768486004228	hypothetical protein; Provisional; Region: PRK13678
768486004229	RNA polymerase sigma factor, SigM family; Region: SigM_subfam; TIGR02950
768486004230	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
768486004231	DNA binding residues [nucleotide binding]
768486004232	Sigma factor regulator N-terminal; Region: Sigma_reg_N; pfam13800
768486004233	Sigma factor regulator C-terminal; Region: Sigma_reg_C; pfam13791
768486004234	SEFIR domain; Region: SEFIR; pfam08357
768486004235	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486004236	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
768486004237	Coenzyme A binding pocket [chemical binding]; other site
768486004238	malate dehydrogenase; Provisional; Region: PRK13529
768486004239	Malic enzyme, N-terminal domain; Region: malic; pfam00390
768486004240	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
768486004241	NAD(P) binding site [chemical binding]; other site
768486004242	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
768486004243	Protein of unknown function (DUF1310); Region: DUF1310; pfam07006
768486004244	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
768486004245	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
768486004246	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
768486004247	DNA-binding site [nucleotide binding]; DNA binding site
768486004248	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
768486004249	pyridoxal 5'-phosphate binding site [chemical binding]; other site
768486004250	homodimer interface [polypeptide binding]; other site
768486004251	catalytic residue [active]
768486004252	ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400
768486004253	Predicted ornithine cyclodeaminase, mu-crystallin homolog [Amino acid transport and metabolism]; Region: COG2423
768486004254	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
768486004255	L-lactate oxidase; Region: L_lactate_ox; TIGR02708
768486004256	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
768486004257	teramer interface [polypeptide binding]; other site
768486004258	active site
768486004259	FMN binding site [chemical binding]; other site
768486004260	catalytic residues [active]
768486004261	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
768486004262	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
768486004263	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
768486004264	Walker A/P-loop; other site
768486004265	ATP binding site [chemical binding]; other site
768486004266	ABC transporter; Region: ABC_tran; pfam00005
768486004267	Q-loop/lid; other site
768486004268	ABC transporter signature motif; other site
768486004269	Walker B; other site
768486004270	D-loop; other site
768486004271	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
768486004272	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
768486004273	potential frameshift: common BLAST hit: gi|217965793|ref|YP_002351471.1| chitinase B
768486004274	ribonuclease HIII; Provisional; Region: PRK00996
768486004275	Domain of unknown function (DUF3378); Region: DUF3378; pfam11858
768486004276	bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590
768486004277	RNA/DNA hybrid binding site [nucleotide binding]; other site
768486004278	active site
768486004279	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
768486004280	Colicin V production protein; Region: Colicin_V; pfam02674
768486004281	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
768486004282	MutS domain III; Region: MutS_III; pfam05192
768486004283	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486004284	Walker A/P-loop; other site
768486004285	ATP binding site [chemical binding]; other site
768486004286	Q-loop/lid; other site
768486004287	ABC transporter signature motif; other site
768486004288	Walker B; other site
768486004289	D-loop; other site
768486004290	H-loop/switch region; other site
768486004291	Smr domain; Region: Smr; pfam01713
768486004292	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
768486004293	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
768486004294	catalytic residues [active]
768486004295	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
768486004296	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
768486004297	GIY-YIG motif/motif A; other site
768486004298	active site
768486004299	catalytic site [active]
768486004300	putative DNA binding site [nucleotide binding]; other site
768486004301	metal binding site [ion binding]; metal-binding site
768486004302	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
768486004303	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
768486004304	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
768486004305	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486004306	Walker A/P-loop; other site
768486004307	ATP binding site [chemical binding]; other site
768486004308	Q-loop/lid; other site
768486004309	ABC transporter signature motif; other site
768486004310	Walker B; other site
768486004311	D-loop; other site
768486004312	H-loop/switch region; other site
768486004313	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
768486004314	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
768486004315	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
768486004316	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
768486004317	catalytic triad [active]
768486004318	V-type ATPase 116kDa subunit family; Region: V_ATPase_I; pfam01496
768486004319	V-type ATP synthase subunit K; Validated; Region: PRK06558
768486004320	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
768486004321	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
768486004322	Archaeal/vacuolar-type H+-ATPase subunit E [Energy production and conversion]; Region: NtpE; COG1390
768486004323	Archaeal/vacuolar-type H+-ATPase subunit C [Energy production and conversion]; Region: NtpC; COG1527
768486004324	V-type ATP synthase subunit C; Provisional; Region: PRK01198; cl00660
768486004325	V-type ATP synthase subunit F; Provisional; Region: PRK01395
768486004326	V-type ATP synthase subunit A; Provisional; Region: PRK04192
768486004327	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
768486004328	V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction.  The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134
768486004329	Walker A motif/ATP binding site; other site
768486004330	Walker B motif; other site
768486004331	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
768486004332	V-type ATP synthase subunit B; Provisional; Region: PRK04196
768486004333	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
768486004334	V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_B; cd01135
768486004335	Walker A motif homologous position; other site
768486004336	Walker B motif; other site
768486004337	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
768486004338	V-type ATP synthase subunit D; Reviewed; Region: PRK00373
768486004339	Cation transport protein; Region: TrkH; cl17365
768486004340	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
768486004341	Cation transport protein; Region: TrkH; pfam02386
768486004342	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
768486004343	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
768486004344	dimer interface [polypeptide binding]; other site
768486004345	active site
768486004346	metal binding site [ion binding]; metal-binding site
768486004347	glutathione binding site [chemical binding]; other site
768486004348	Contains a crystal structure of the Nudix hydrolase from Enterococcus faecalis, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_25; cd04684
768486004349	nudix motif; other site
768486004350	sugar phosphate phosphatase; Provisional; Region: PRK10513
768486004351	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486004352	active site
768486004353	motif I; other site
768486004354	motif II; other site
768486004355	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486004356	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
768486004357	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
768486004358	Zn2+ binding site [ion binding]; other site
768486004359	Mg2+ binding site [ion binding]; other site
768486004360	potential frameshift: common BLAST hit: gi|389869260|ref|YP_006376683.1| lipoate--protein ligase A
768486004361	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
768486004362	Domain of unknown function (DUF1934); Region: DUF1934; pfam09148
768486004363	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; pfam05066
768486004364	RNA polymerase sigma-70 factor, TIGR02954 family; Region: Sig70_famx3
768486004365	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
768486004366	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
768486004367	DNA binding residues [nucleotide binding]
768486004368	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
768486004369	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
768486004370	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
768486004371	DNA-binding site [nucleotide binding]; DNA binding site
768486004372	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
768486004373	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
768486004374	dipeptidase, putative; Region: dipeptidaselike; TIGR01887
768486004375	active site
768486004376	metal binding site [ion binding]; metal-binding site
768486004377	Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU)...; Region: Glycosylasparaginase; cd04513
768486004378	active site
768486004379	dimer interface [polypeptide binding]; other site
768486004380	catalytic nucleophile [active]
768486004381	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
768486004382	active site
768486004383	P-loop; other site
768486004384	phosphorylation site [posttranslational modification]
768486004385	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
768486004386	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
768486004387	glycine reductase, selenoprotein B; Region: gly_red_sel_B; TIGR01917
768486004388	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
768486004389	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
768486004390	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
768486004391	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
768486004392	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
768486004393	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
768486004394	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
768486004395	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
768486004396	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
768486004397	Phosphoglycerate kinase; Region: PGK; pfam00162
768486004398	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
768486004399	substrate binding site [chemical binding]; other site
768486004400	hinge regions; other site
768486004401	ADP binding site [chemical binding]; other site
768486004402	catalytic site [active]
768486004403	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
768486004404	triosephosphate isomerase; Provisional; Region: PRK14565
768486004405	substrate binding site [chemical binding]; other site
768486004406	dimer interface [polypeptide binding]; other site
768486004407	catalytic triad [active]
768486004408	enolase; Provisional; Region: eno; PRK00077
768486004409	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
768486004410	dimer interface [polypeptide binding]; other site
768486004411	metal binding site [ion binding]; metal-binding site
768486004412	substrate binding pocket [chemical binding]; other site
768486004413	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
768486004414	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
768486004415	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK08588
768486004416	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
768486004417	metal binding site [ion binding]; metal-binding site
768486004418	dimer interface [polypeptide binding]; other site
768486004419	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
768486004420	NH_3: A subgroup of nucleoside hydrolases. This group contains eukaryotic and bacterial proteins similar to nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes...; Region: nuc_hydro_3; cd02653
768486004421	active site
768486004422	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
768486004423	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
768486004424	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486004425	Coenzyme A binding pocket [chemical binding]; other site
768486004426	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
768486004427	Esterase/lipase [General function prediction only]; Region: COG1647
768486004428	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
768486004429	ribonuclease R; Region: RNase_R; TIGR02063
768486004430	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
768486004431	RNB domain; Region: RNB; pfam00773
768486004432	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
768486004433	RNA binding site [nucleotide binding]; other site
768486004434	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
768486004435	SmpB-tmRNA interface; other site
768486004436	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
768486004437	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
768486004438	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
768486004439	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
768486004440	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
768486004441	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
768486004442	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
768486004443	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
768486004444	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
768486004445	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
768486004446	beta subunit interaction interface [polypeptide binding]; other site
768486004447	Walker A motif; other site
768486004448	ATP binding site [chemical binding]; other site
768486004449	Walker B motif; other site
768486004450	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
768486004451	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
768486004452	core domain interface [polypeptide binding]; other site
768486004453	delta subunit interface [polypeptide binding]; other site
768486004454	epsilon subunit interface [polypeptide binding]; other site
768486004455	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
768486004456	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
768486004457	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
768486004458	alpha subunit interaction interface [polypeptide binding]; other site
768486004459	Walker A motif; other site
768486004460	ATP binding site [chemical binding]; other site
768486004461	Walker B motif; other site
768486004462	inhibitor binding site; inhibition site
768486004463	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
768486004464	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
768486004465	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
768486004466	gamma subunit interface [polypeptide binding]; other site
768486004467	epsilon subunit interface [polypeptide binding]; other site
768486004468	LBP interface [polypeptide binding]; other site
768486004469	transport-energizing ATPase, TRC40/GET3/ArsA family; Region: GET3_arsA_TRC40; TIGR00345
768486004470	Protein of unknown function (DUF1146); Region: DUF1146; cl11486
768486004471	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
768486004472	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
768486004473	hinge; other site
768486004474	active site
768486004475	DNA-directed RNA polymerase subunit beta; Region: EpuA; pfam11772
768486004476	Haemolytic domain; Region: Haemolytic; pfam01809
768486004477	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486004478	Coenzyme A binding pocket [chemical binding]; other site
768486004479	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
768486004480	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
768486004481	nucleotide binding site [chemical binding]; other site
768486004482	Protein of unknown function (DUF2969); Region: DUF2969; pfam11184
768486004483	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
768486004484	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
768486004485	DNA-binding site [nucleotide binding]; DNA binding site
768486004486	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
768486004487	Uncharacterized conserved protein [Function unknown]; Region: COG1739
768486004488	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
768486004489	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
768486004490	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
768486004491	active site
768486004492	P-loop; other site
768486004493	phosphorylation site [posttranslational modification]
768486004494	potential frameshift: common BLAST hit: gi|332686409|ref|YP_004456183.1| DNA transporter ATPase
768486004495	comF family protein; Region: comF; TIGR00201
768486004496	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
768486004497	active site
768486004498	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
768486004499	30S subunit binding site; other site
768486004500	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
768486004501	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
768486004502	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
768486004503	nucleotide binding region [chemical binding]; other site
768486004504	ATP-binding site [chemical binding]; other site
768486004505	SEC-C motif; Region: SEC-C; pfam02810
768486004506	peptide chain release factor 2; Provisional; Region: PRK05589
768486004507	This domain is found in peptide chain release factors; Region: PCRF; smart00937
768486004508	RF-1 domain; Region: RF-1; pfam00472
768486004509	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
768486004510	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486004511	Walker A/P-loop; other site
768486004512	ATP binding site [chemical binding]; other site
768486004513	Q-loop/lid; other site
768486004514	ABC transporter signature motif; other site
768486004515	Walker B; other site
768486004516	D-loop; other site
768486004517	H-loop/switch region; other site
768486004518	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
768486004519	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
768486004520	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
768486004521	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
768486004522	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
768486004523	putative active site [active]
768486004524	catalytic site [active]
768486004525	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
768486004526	putative active site [active]
768486004527	catalytic site [active]
768486004528	phosphate binding protein; Region: ptsS_2; TIGR02136
768486004529	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
768486004530	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
768486004531	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486004532	dimer interface [polypeptide binding]; other site
768486004533	conserved gate region; other site
768486004534	putative PBP binding loops; other site
768486004535	ABC-ATPase subunit interface; other site
768486004536	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
768486004537	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486004538	dimer interface [polypeptide binding]; other site
768486004539	conserved gate region; other site
768486004540	putative PBP binding loops; other site
768486004541	ABC-ATPase subunit interface; other site
768486004542	phosphate transporter ATP-binding protein; Provisional; Region: PRK14237
768486004543	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
768486004544	Walker A/P-loop; other site
768486004545	ATP binding site [chemical binding]; other site
768486004546	Q-loop/lid; other site
768486004547	ABC transporter signature motif; other site
768486004548	Walker B; other site
768486004549	D-loop; other site
768486004550	H-loop/switch region; other site
768486004551	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
768486004552	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
768486004553	Walker A/P-loop; other site
768486004554	ATP binding site [chemical binding]; other site
768486004555	Q-loop/lid; other site
768486004556	ABC transporter signature motif; other site
768486004557	Walker B; other site
768486004558	D-loop; other site
768486004559	H-loop/switch region; other site
768486004560	potential frameshift: common BLAST hit: gi|29376303|ref|NP_815457.1| PhoU family protein
768486004561	Uncharacterized conserved protein [Function unknown]; Region: COG3595
768486004562	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
768486004563	PspC domain; Region: PspC; pfam04024
768486004564	Membrane protein of unknown function; Region: DUF360; pfam04020
768486004565	HPr kinase/phosphorylase; Provisional; Region: PRK05428
768486004566	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
768486004567	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
768486004568	Hpr binding site; other site
768486004569	active site
768486004570	homohexamer subunit interaction site [polypeptide binding]; other site
768486004571	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
768486004572	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
768486004573	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
768486004574	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
768486004575	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
768486004576	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
768486004577	active site
768486004578	tetramer interface; other site
768486004579	Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain [General function prediction only]; Region: COG4768
768486004580	YtxH-like protein; Region: YtxH; pfam12732
768486004581	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
768486004582	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
768486004583	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
768486004584	active site
768486004585	catabolite control protein A; Region: ccpA; TIGR01481
768486004586	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
768486004587	DNA binding site [nucleotide binding]
768486004588	domain linker motif; other site
768486004589	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
768486004590	dimerization interface [polypeptide binding]; other site
768486004591	effector binding site; other site
768486004592	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
768486004593	Transglycosylase; Region: Transgly; pfam00912
768486004594	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
768486004595	endonuclease IV; Provisional; Region: PRK01060
768486004596	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
768486004597	AP (apurinic/apyrimidinic) site pocket; other site
768486004598	DNA interaction; other site
768486004599	Metal-binding active site; metal-binding site
768486004600	manganese transport protein MntH; Reviewed; Region: PRK00701
768486004601	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
768486004602	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3763
768486004603	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
768486004604	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
768486004605	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486004606	Walker A/P-loop; other site
768486004607	ATP binding site [chemical binding]; other site
768486004608	Q-loop/lid; other site
768486004609	ABC transporter signature motif; other site
768486004610	Walker B; other site
768486004611	D-loop; other site
768486004612	H-loop/switch region; other site
768486004613	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
768486004614	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
768486004615	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486004616	Walker A/P-loop; other site
768486004617	ATP binding site [chemical binding]; other site
768486004618	Q-loop/lid; other site
768486004619	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
768486004620	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
768486004621	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
768486004622	putative active site [active]
768486004623	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
768486004624	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
768486004625	NAD binding site [chemical binding]; other site
768486004626	sugar binding site [chemical binding]; other site
768486004627	divalent metal binding site [ion binding]; other site
768486004628	tetramer (dimer of dimers) interface [polypeptide binding]; other site
768486004629	dimer interface [polypeptide binding]; other site
768486004630	6-phospho-beta-glucosidase; Reviewed; Region: arb; PRK09593
768486004631	beta-galactosidase; Region: BGL; TIGR03356
768486004632	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
768486004633	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
768486004634	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
768486004635	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
768486004636	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
768486004637	active site
768486004638	substrate binding site [chemical binding]; other site
768486004639	metal binding site [ion binding]; metal-binding site
768486004640	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
768486004641	dimerization interface [polypeptide binding]; other site
768486004642	putative DNA binding site [nucleotide binding]; other site
768486004643	putative Zn2+ binding site [ion binding]; other site
768486004644	Kinase/pyrophosphorylase; Region: Kinase-PPPase; pfam03618
768486004645	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
768486004646	metal binding site 2 [ion binding]; metal-binding site
768486004647	putative DNA binding helix; other site
768486004648	metal binding site 1 [ion binding]; metal-binding site
768486004649	dimer interface [polypeptide binding]; other site
768486004650	structural Zn2+ binding site [ion binding]; other site
768486004651	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
768486004652	Yqey-like protein; Region: YqeY; pfam09424
768486004653	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
768486004654	PhoH-like protein; Region: PhoH; pfam02562
768486004655	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
768486004656	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486004657	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
768486004658	Zn2+ binding site [ion binding]; other site
768486004659	Mg2+ binding site [ion binding]; other site
768486004660	metal-binding heat shock protein; Provisional; Region: PRK00016
768486004661	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
768486004662	GTPase Era; Reviewed; Region: era; PRK00089
768486004663	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
768486004664	G1 box; other site
768486004665	GTP/Mg2+ binding site [chemical binding]; other site
768486004666	Switch I region; other site
768486004667	G2 box; other site
768486004668	Switch II region; other site
768486004669	G3 box; other site
768486004670	G4 box; other site
768486004671	G5 box; other site
768486004672	KH domain; Region: KH_2; pfam07650
768486004673	Recombination protein O N terminal; Region: RecO_N; pfam11967
768486004674	DNA repair protein RecO; Region: reco; TIGR00613
768486004675	Recombination protein O C terminal; Region: RecO_C; pfam02565
768486004676	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
768486004677	dimer interface [polypeptide binding]; other site
768486004678	motif 1; other site
768486004679	active site
768486004680	motif 2; other site
768486004681	motif 3; other site
768486004682	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
768486004683	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
768486004684	Chain length determinant protein; Region: Wzz; cl15801
768486004685	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
768486004686	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
768486004687	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
768486004688	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
768486004689	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
768486004690	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
768486004691	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
768486004692	NAD(P) binding site [chemical binding]; other site
768486004693	homodimer interface [polypeptide binding]; other site
768486004694	substrate binding site [chemical binding]; other site
768486004695	active site
768486004696	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
768486004697	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
768486004698	putative trimer interface [polypeptide binding]; other site
768486004699	putative CoA binding site [chemical binding]; other site
768486004700	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
768486004701	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
768486004702	inhibitor-cofactor binding pocket; inhibition site
768486004703	pyridoxal 5'-phosphate binding site [chemical binding]; other site
768486004704	catalytic residue [active]
768486004705	Bacterial sugar transferase; Region: Bac_transf; pfam02397
768486004706	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
768486004707	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
768486004708	putative ADP-binding pocket [chemical binding]; other site
768486004709	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
768486004710	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
768486004711	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
768486004712	potential frameshift: common BLAST hit: gi|328957721|ref|YP_004375107.1| putative teichoic acid/polysaccharide export protein
768486004713	OxaA-like protein precursor; Provisional; Region: PRK02463
768486004714	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
768486004715	Acylphosphatases [Energy production and conversion]; Region: AcyP; COG1254
768486004716	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
768486004717	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
768486004718	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
768486004719	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
768486004720	Zn2+ binding site [ion binding]; other site
768486004721	Mg2+ binding site [ion binding]; other site
768486004722	Fibronectin-binding protein (FBP); Region: FBP; pfam07299
768486004723	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
768486004724	ClC sycA-like chloride channel proteins. This ClC family presents in bacteria, where it facilitates acid resistance in acidic soil. Mutation of this gene (sycA) in Rhizobium tropici CIAT899 causes serious deficiencies in nodule development, nodulation...; Region: ClC_sycA_like; cd03682
768486004725	putative Cl- selectivity filter; other site
768486004726	putative pore gating glutamate residue; other site
768486004727	Uncharacterized conserved protein [Function unknown]; Region: COG1434
768486004728	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
768486004729	putative active site [active]
768486004730	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
768486004731	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
768486004732	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
768486004733	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
768486004734	DNA-binding site [nucleotide binding]; DNA binding site
768486004735	RNA-binding motif; other site
768486004736	potential frameshift: common BLAST hit: gi|29376872|ref|NP_816026.1| DNA polymerase III, epsilon subunit/ATP-dependent helicase DinG
768486004737	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5353
768486004738	aspartate aminotransferase; Provisional; Region: PRK05764
768486004739	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
768486004740	pyridoxal 5'-phosphate binding site [chemical binding]; other site
768486004741	homodimer interface [polypeptide binding]; other site
768486004742	catalytic residue [active]
768486004743	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
768486004744	AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs.  This domain is a...; Region: AsnRS_cyto_like_N; cd04323
768486004745	putative dimer interface [polypeptide binding]; other site
768486004746	putative anticodon binding site; other site
768486004747	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
768486004748	homodimer interface [polypeptide binding]; other site
768486004749	motif 1; other site
768486004750	motif 2; other site
768486004751	active site
768486004752	motif 3; other site
768486004753	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
768486004754	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
768486004755	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
768486004756	metal-binding site [ion binding]
768486004757	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
768486004758	Soluble P-type ATPase [General function prediction only]; Region: COG4087
768486004759	Amino acid permease; Region: AA_permease_2; pfam13520
768486004760	topology modulation protein; Reviewed; Region: PRK08118
768486004761	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cd02019
768486004762	active site
768486004763	copper transport repressor, CopY/TcrY family; Region: CopY_TcrY; TIGR02698
768486004764	Penicillinase repressor; Region: Pencillinase_R; pfam03965
768486004765	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
768486004766	metal-binding site [ion binding]
768486004767	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
768486004768	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
768486004769	metal-binding site [ion binding]
768486004770	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
768486004771	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486004772	motif II; other site
768486004773	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
768486004774	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
768486004775	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486004776	motif II; other site
768486004777	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
768486004778	PBP superfamily domain; Region: PBP_like_2; cl17296
768486004779	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
768486004780	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; cl02930
768486004781	ATPase, P-type (transporting), HAD superfamily, subfamily IC; Region: ATPase_P-type; TIGR01494
768486004782	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
768486004783	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486004784	motif II; other site
768486004785	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
768486004786	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
768486004787	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
768486004788	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
768486004789	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
768486004790	dimer interface [polypeptide binding]; other site
768486004791	phosphorylation site [posttranslational modification]
768486004792	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
768486004793	ATP binding site [chemical binding]; other site
768486004794	Mg2+ binding site [ion binding]; other site
768486004795	G-X-G motif; other site
768486004796	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
768486004797	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486004798	active site
768486004799	phosphorylation site [posttranslational modification]
768486004800	intermolecular recognition site; other site
768486004801	dimerization interface [polypeptide binding]; other site
768486004802	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
768486004803	DNA binding site [nucleotide binding]
768486004804	Protein of unknown function (DUF523); Region: DUF523; pfam04463
768486004805	putative DNA-binding protein; Validated; Region: PRK00118
768486004806	Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297
768486004807	signal recognition particle protein; Provisional; Region: PRK10867
768486004808	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
768486004809	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
768486004810	P loop; other site
768486004811	GTP binding site [chemical binding]; other site
768486004812	Signal peptide binding domain; Region: SRP_SPB; pfam02978
768486004813	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
768486004814	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
768486004815	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cl17426
768486004816	NADP+ binding site [chemical binding]; other site
768486004817	Predicted flavoprotein [General function prediction only]; Region: COG0431
768486004818	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
768486004819	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
768486004820	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
768486004821	Walker A/P-loop; other site
768486004822	ATP binding site [chemical binding]; other site
768486004823	Q-loop/lid; other site
768486004824	ABC transporter signature motif; other site
768486004825	Walker B; other site
768486004826	D-loop; other site
768486004827	H-loop/switch region; other site
768486004828	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
768486004829	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
768486004830	KH domain; Region: KH_4; pfam13083
768486004831	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
768486004832	RimM N-terminal domain; Region: RimM; pfam01782
768486004833	PRC-barrel domain; Region: PRC; pfam05239
768486004834	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
768486004835	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
768486004836	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
768486004837	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
768486004838	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
768486004839	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
768486004840	DNA-binding site [nucleotide binding]; DNA binding site
768486004841	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
768486004842	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
768486004843	beta-galactosidase; Region: BGL; TIGR03356
768486004844	Histidine kinase-like ATPases; Region: HATPase_c; smart00387
768486004845	G-X-G motif; other site
768486004846	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
768486004847	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486004848	active site
768486004849	phosphorylation site [posttranslational modification]
768486004850	intermolecular recognition site; other site
768486004851	dimerization interface [polypeptide binding]; other site
768486004852	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
768486004853	DNA binding site [nucleotide binding]
768486004854	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
768486004855	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
768486004856	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
768486004857	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
768486004858	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
768486004859	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
768486004860	potential frameshift: common BLAST hit: gi|281491818|ref|YP_003353798.1| PepP/PepQ-like peptidase
768486004861	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
768486004862	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
768486004863	DNA binding residues [nucleotide binding]
768486004864	putative dimer interface [polypeptide binding]; other site
768486004865	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
768486004866	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
768486004867	homodimer interface [polypeptide binding]; other site
768486004868	substrate-cofactor binding pocket; other site
768486004869	pyridoxal 5'-phosphate binding site [chemical binding]; other site
768486004870	catalytic residue [active]
768486004871	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
768486004872	homotrimer interaction site [polypeptide binding]; other site
768486004873	putative active site [active]
768486004874	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
768486004875	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
768486004876	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
768486004877	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
768486004878	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
768486004879	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
768486004880	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
768486004881	YheO-like PAS domain; Region: PAS_6; pfam08348
768486004882	HTH domain; Region: HTH_22; pfam13309
768486004883	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
768486004884	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486004885	Coenzyme A binding pocket [chemical binding]; other site
768486004886	potential frameshift: common BLAST hit: gi|29375786|ref|NP_814940.1| acetolactate synthase
768486004887	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; pfam03306
768486004888	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
768486004889	potential frameshift: common BLAST hit: gi|383329203|ref|YP_005355087.1| IS1251-like transposase
768486004890	Transposase; Region: DDE_Tnp_ISL3; pfam01610
768486004891	Transcriptional regulators [Transcription]; Region: MarR; COG1846
768486004892	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
768486004893	putative DNA binding site [nucleotide binding]; other site
768486004894	putative Zn2+ binding site [ion binding]; other site
768486004895	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
768486004896	dimer interface [polypeptide binding]; other site
768486004897	FMN binding site [chemical binding]; other site
768486004898	Uncharacterized conserved protein [Function unknown]; Region: COG1359
768486004899	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
768486004900	Cell-wall surface anchor repeat; Region: C-term_anchor; pfam13461
768486004901	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
768486004902	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
768486004903	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cl02915
768486004904	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
768486004905	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
768486004906	Int/Topo IB signature motif; other site
768486004907	Predicted membrane protein [Function unknown]; Region: XynA; COG2314
768486004908	Domain of unknown function (DUF955); Region: DUF955; pfam06114
768486004909	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486004910	non-specific DNA binding site [nucleotide binding]; other site
768486004911	salt bridge; other site
768486004912	sequence-specific DNA binding site [nucleotide binding]; other site
768486004913	Helix-turn-helix domain; Region: HTH_17; cl17695
768486004914	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
768486004915	ORF6C domain; Region: ORF6C; pfam10552
768486004916	Protein of unknown function (DUF1071); Region: DUF1071; pfam06378
768486004917	Protein of unknown function (DUF968); Region: DUF968; pfam06147
768486004918	N-terminal phage replisome organiser (Phage_rep_org_N); Region: Phage_rep_org_N; pfam09681
768486004919	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486004920	Walker A motif; other site
768486004921	ATP binding site [chemical binding]; other site
768486004922	Walker B motif; other site
768486004923	arginine finger; other site
768486004924	Protein of unknown function (DUF1064); Region: DUF1064; pfam06356
768486004925	Protein of unknown function (DUF1140); Region: DUF1140; pfam06600
768486004926	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u3; cd11540
768486004927	putative metal binding site [ion binding]; other site
768486004928	DNA repair and recombination protein RadA; Validated; Region: radA; PRK04301
768486004929	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
768486004930	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
768486004931	active site
768486004932	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
768486004933	Phage portal protein; Region: Phage_portal; pfam04860
768486004934	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
768486004935	oligomer interface [polypeptide binding]; other site
768486004936	active site residues [active]
768486004937	Phage capsid family; Region: Phage_capsid; pfam05065
768486004938	Phage-related minor tail protein [Function unknown]; Region: COG5280
768486004939	membrane protein P6; Region: PHA01399
768486004940	Phage-related protein [Function unknown]; Region: COG4722
768486004941	Phage tail protein; Region: Sipho_tail; cl17486
768486004942	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
768486004943	Hepatic lectin, N-terminal domain; Region: Lectin_N; pfam03954
768486004944	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
768486004945	amidase catalytic site [active]
768486004946	Zn binding residues [ion binding]; other site
768486004947	substrate binding site [chemical binding]; other site
768486004948	Abi-like protein; Region: Abi_2; cl01988
768486004949	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
768486004950	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
768486004951	SdpI/YhfL protein family; Region: SdpI; pfam13630
768486004952	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
768486004953	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486004954	active site
768486004955	phosphorylation site [posttranslational modification]
768486004956	intermolecular recognition site; other site
768486004957	dimerization interface [polypeptide binding]; other site
768486004958	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
768486004959	DNA binding site [nucleotide binding]
768486004960	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
768486004961	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
768486004962	dimerization interface [polypeptide binding]; other site
768486004963	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
768486004964	dimer interface [polypeptide binding]; other site
768486004965	phosphorylation site [posttranslational modification]
768486004966	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
768486004967	ATP binding site [chemical binding]; other site
768486004968	Mg2+ binding site [ion binding]; other site
768486004969	G-X-G motif; other site
768486004970	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
768486004971	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
768486004972	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
768486004973	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
768486004974	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
768486004975	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
768486004976	Sulfatase; Region: Sulfatase; pfam00884
768486004977	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
768486004978	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
768486004979	putative RNA binding site [nucleotide binding]; other site
768486004980	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486004981	S-adenosylmethionine binding site [chemical binding]; other site
768486004982	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
768486004983	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
768486004984	active site
768486004985	catalytic residue [active]
768486004986	dimer interface [polypeptide binding]; other site
768486004987	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
768486004988	putative deacylase active site [active]
768486004989	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
768486004990	HI0933-like protein; Region: HI0933_like; pfam03486
768486004991	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
768486004992	potential frameshift: common BLAST hit: gi|29375982|ref|NP_815136.1| glutamate dehydrogenase
768486004993	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
768486004994	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
768486004995	active site
768486004996	dimer interface [polypeptide binding]; other site
768486004997	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
768486004998	dimer interface [polypeptide binding]; other site
768486004999	active site
768486005000	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
768486005001	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
768486005002	Int/Topo IB signature motif; other site
768486005003	SIR2-like domain; Region: SIR2_2; pfam13289
768486005004	Short C-terminal domain; Region: SHOCT; pfam09851
768486005005	Domain of unknown function (DUF955); Region: DUF955; pfam06114
768486005006	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
768486005007	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486005008	non-specific DNA binding site [nucleotide binding]; other site
768486005009	salt bridge; other site
768486005010	sequence-specific DNA binding site [nucleotide binding]; other site
768486005011	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486005012	non-specific DNA binding site [nucleotide binding]; other site
768486005013	salt bridge; other site
768486005014	sequence-specific DNA binding site [nucleotide binding]; other site
768486005015	Protein of unknown function (Hypoth_ymh); Region: Hypoth_Ymh; pfam09509
768486005016	Protein of unknown function (DUF1064); Region: DUF1064; pfam06356
768486005017	Protein of unknown function (DUF3955); Region: DUF3955; pfam13127
768486005018	Protein of unknown function (DUF1093); Region: DUF1093; pfam06486
768486005019	phage transcriptional regulator, ArpU family; Region: phage_arpU; TIGR01637
768486005020	Domain of unknown function (DUF2479); Region: DUF2479; pfam10651
768486005021	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
768486005022	amidase catalytic site [active]
768486005023	Zn binding residues [ion binding]; other site
768486005024	substrate binding site [chemical binding]; other site
768486005025	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
768486005026	DNA-binding site [nucleotide binding]; DNA binding site
768486005027	RNA-binding motif; other site
768486005028	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
768486005029	Glycerophosphodiester phosphodiesterase domain of Agrobacterium tumefaciens and similar proteins; Region: GDPD_AtGDE_like; cd08566
768486005030	putative active site [active]
768486005031	catalytic site [active]
768486005032	putative metal binding site [ion binding]; other site
768486005033	oligomer interface [polypeptide binding]; other site
768486005034	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
768486005035	amidase catalytic site [active]
768486005036	Zn binding residues [ion binding]; other site
768486005037	substrate binding site [chemical binding]; other site
768486005038	Protein of unknown function (DUF4231); Region: DUF4231; pfam14015
768486005039	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
768486005040	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
768486005041	active site
768486005042	Uncharacterized conserved protein [Function unknown]; Region: COG1359
768486005043	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
768486005044	Protein of unknown function (DUF4231); Region: DUF4231; pfam14015
768486005045	potential frameshift: common BLAST hit: gi|29376432|ref|NP_815586.1| glycerophosphoryl diester phosphodiesterase family protein
768486005046	potential frameshift: common BLAST hit: gi|29376432|ref|NP_815586.1| glycerophosphoryl diester phosphodiesterase family protein
768486005047	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
768486005048	Uncharacterized conserved protein [Function unknown]; Region: COG0398
768486005049	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
768486005050	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
768486005051	WHG domain; Region: WHG; pfam13305
768486005052	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
768486005053	Putative Catalytic site; other site
768486005054	DXD motif; other site
768486005055	exosortase A system-associated amidotransferase 1; Region: eps_aminotran_1; TIGR03108
768486005056	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
768486005057	active site
768486005058	dimer interface [polypeptide binding]; other site
768486005059	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
768486005060	Ligand Binding Site [chemical binding]; other site
768486005061	Molecular Tunnel; other site
768486005062	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4876
768486005063	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
768486005064	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
768486005065	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
768486005066	folate binding site [chemical binding]; other site
768486005067	NADP+ binding site [chemical binding]; other site
768486005068	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
768486005069	Periplasmic binding protein FeuA.  These proteins have predicted to function as initial receptors in ABC transport of metal ions in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: FeuA; cd01138
768486005070	putative ligand binding residues [chemical binding]; other site
768486005071	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
768486005072	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
768486005073	Walker A/P-loop; other site
768486005074	ATP binding site [chemical binding]; other site
768486005075	Q-loop/lid; other site
768486005076	ABC transporter signature motif; other site
768486005077	Walker B; other site
768486005078	D-loop; other site
768486005079	H-loop/switch region; other site
768486005080	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
768486005081	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
768486005082	ABC-ATPase subunit  interface; other site
768486005083	dimer interface [polypeptide binding]; other site
768486005084	putative PBP binding regions; other site
768486005085	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
768486005086	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
768486005087	ABC-ATPase subunit  interface; other site
768486005088	dimer interface [polypeptide binding]; other site
768486005089	putative PBP binding regions; other site
768486005090	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
768486005091	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
768486005092	Rhomboid family; Region: Rhomboid; pfam01694
768486005093	Bacterial protein of unknown function (DUF910); Region: DUF910; pfam06014
768486005094	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
768486005095	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
768486005096	nucleotide binding site [chemical binding]; other site
768486005097	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
768486005098	active site residue [active]
768486005099	Uncharacterized conserved protein [Function unknown]; Region: COG3189
768486005100	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
768486005101	Protein of unknown function (DUF3042); Region: DUF3042; pfam11240
768486005102	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
768486005103	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
768486005104	NAD binding site [chemical binding]; other site
768486005105	homodimer interface [polypeptide binding]; other site
768486005106	active site
768486005107	substrate binding site [chemical binding]; other site
768486005108	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
768486005109	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
768486005110	Galactose-1-phosphate uridyl transferase, C-terminal domain; Region: GalP_UDP_tr_C; pfam02744
768486005111	Transcriptional regulators [Transcription]; Region: PurR; COG1609
768486005112	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
768486005113	DNA binding site [nucleotide binding]
768486005114	domain linker motif; other site
768486005115	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
768486005116	putative dimerization interface [polypeptide binding]; other site
768486005117	putative ligand binding site [chemical binding]; other site
768486005118	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
768486005119	Glycoprotease family; Region: Peptidase_M22; pfam00814
768486005120	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
768486005121	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486005122	Coenzyme A binding pocket [chemical binding]; other site
768486005123	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
768486005124	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486005125	Coenzyme A binding pocket [chemical binding]; other site
768486005126	UGMP family protein; Validated; Region: PRK09604
768486005127	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
768486005128	nucleotide binding site [chemical binding]; other site
768486005129	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
768486005130	active site
768486005131	catalytic site [active]
768486005132	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
768486005133	Chain length determinant protein; Region: Wzz; cl15801
768486005134	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
768486005135	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
768486005136	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
768486005137	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
768486005138	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
768486005139	NAD(P) binding site [chemical binding]; other site
768486005140	homodimer interface [polypeptide binding]; other site
768486005141	substrate binding site [chemical binding]; other site
768486005142	active site
768486005143	O-Antigen ligase; Region: Wzy_C; pfam04932
768486005144	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
768486005145	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
768486005146	active site
768486005147	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
768486005148	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
768486005149	ligand binding site [chemical binding]; other site
768486005150	flexible hinge region; other site
768486005151	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
768486005152	arginine deiminase; Provisional; Region: PRK01388
768486005153	ornithine carbamoyltransferase; Validated; Region: PRK02102
768486005154	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
768486005155	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
768486005156	carbamate kinase; Reviewed; Region: PRK12686
768486005157	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
768486005158	putative substrate binding site [chemical binding]; other site
768486005159	nucleotide binding site [chemical binding]; other site
768486005160	nucleotide binding site [chemical binding]; other site
768486005161	homodimer interface [polypeptide binding]; other site
768486005162	arginyl-tRNA synthetase; Reviewed; Region: PRK12451
768486005163	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
768486005164	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
768486005165	active site
768486005166	HIGH motif; other site
768486005167	KMSK motif region; other site
768486005168	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
768486005169	tRNA binding surface [nucleotide binding]; other site
768486005170	anticodon binding site; other site
768486005171	Arginine repressor [Transcription]; Region: ArgR; COG1438
768486005172	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
768486005173	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
768486005174	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
768486005175	rRNA interaction site [nucleotide binding]; other site
768486005176	S8 interaction site; other site
768486005177	putative laminin-1 binding site; other site
768486005178	elongation factor Ts; Provisional; Region: tsf; PRK09377
768486005179	UBA/TS-N domain; Region: UBA; pfam00627
768486005180	Elongation factor TS; Region: EF_TS; pfam00889
768486005181	Elongation factor TS; Region: EF_TS; pfam00889
768486005182	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
768486005183	putative nucleotide binding site [chemical binding]; other site
768486005184	uridine monophosphate binding site [chemical binding]; other site
768486005185	homohexameric interface [polypeptide binding]; other site
768486005186	ribosome recycling factor; Reviewed; Region: frr; PRK00083
768486005187	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
768486005188	hinge region; other site
768486005189	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
768486005190	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
768486005191	catalytic residue [active]
768486005192	putative FPP diphosphate  binding site; other site
768486005193	putative FPP binding hydrophobic cleft; other site
768486005194	dimer interface [polypeptide binding]; other site
768486005195	putative IPP diphosphate binding site; other site
768486005196	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
768486005197	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
768486005198	RIP metalloprotease RseP; Region: TIGR00054
768486005199	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
768486005200	active site
768486005201	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
768486005202	protein binding site [polypeptide binding]; other site
768486005203	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
768486005204	putative substrate binding region [chemical binding]; other site
768486005205	prolyl-tRNA synthetase; Provisional; Region: PRK09194
768486005206	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
768486005207	dimer interface [polypeptide binding]; other site
768486005208	motif 1; other site
768486005209	active site
768486005210	motif 2; other site
768486005211	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
768486005212	putative deacylase active site [active]
768486005213	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
768486005214	active site
768486005215	motif 3; other site
768486005216	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
768486005217	anticodon binding site; other site
768486005218	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
768486005219	classical (c) SDRs; Region: SDR_c; cd05233
768486005220	NAD(P) binding site [chemical binding]; other site
768486005221	active site
768486005222	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
768486005223	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
768486005224	active site
768486005225	catalytic tetrad [active]
768486005226	Predicted transcriptional regulators [Transcription]; Region: COG1733
768486005227	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
768486005228	dimerization interface [polypeptide binding]; other site
768486005229	putative Zn2+ binding site [ion binding]; other site
768486005230	putative DNA binding site [nucleotide binding]; other site
768486005231	potential frameshift: common BLAST hit: gi|29376875|ref|NP_816029.1| DNA polymerase III PolC
768486005232	ribosome maturation protein RimP; Reviewed; Region: PRK00092
768486005233	Sm and related proteins; Region: Sm_like; cl00259
768486005234	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
768486005235	putative oligomer interface [polypeptide binding]; other site
768486005236	putative RNA binding site [nucleotide binding]; other site
768486005237	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
768486005238	NusA N-terminal domain; Region: NusA_N; pfam08529
768486005239	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
768486005240	RNA binding site [nucleotide binding]; other site
768486005241	homodimer interface [polypeptide binding]; other site
768486005242	NusA-like KH domain; Region: KH_5; pfam13184
768486005243	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
768486005244	G-X-X-G motif; other site
768486005245	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
768486005246	putative RNA binding cleft [nucleotide binding]; other site
768486005247	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
768486005248	potential frameshift: common BLAST hit: gi|29375843|ref|NP_814997.1| translation initiation factor IF-2
768486005249	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
768486005250	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK01550
768486005251	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
768486005252	RNA binding site [nucleotide binding]; other site
768486005253	active site
768486005254	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
768486005255	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
768486005256	active site
768486005257	Riboflavin kinase; Region: Flavokinase; pfam01687
768486005258	glucose-1-dehydrogenase; Provisional; Region: PRK08936
768486005259	glucose 1 dehydrogenase (GlcDH), classical (c) SDRs; Region: GlcDH_SDR_c; cd05358
768486005260	NAD binding site [chemical binding]; other site
768486005261	homodimer interface [polypeptide binding]; other site
768486005262	active site
768486005263	Helix-turn-helix domain; Region: HTH_17; pfam12728
768486005264	putative heme d1 biosynthesis radical SAM protein NirJ2; Region: rSAM_NirJ2; TIGR04055
768486005265	putative heme d1 biosynthesis radical SAM protein NirJ2; Region: rSAM_NirJ2; TIGR04055
768486005266	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
768486005267	Branched-chain amino acid transport protein; Region: Branch_AA_trans; pfam05525
768486005268	WxL domain surface cell wall-binding; Region: WxL; pfam13731
768486005269	WxL domain surface cell wall-binding; Region: WxL; pfam13731
768486005270	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
768486005271	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
768486005272	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
768486005273	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
768486005274	LytTr DNA-binding domain; Region: LytTR; pfam04397
768486005275	Histidine kinase; Region: His_kinase; pfam06580
768486005276	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
768486005277	Mg2+ binding site [ion binding]; other site
768486005278	G-X-G motif; other site
768486005279	Response regulator receiver domain; Region: Response_reg; pfam00072
768486005280	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486005281	active site
768486005282	phosphorylation site [posttranslational modification]
768486005283	intermolecular recognition site; other site
768486005284	dimerization interface [polypeptide binding]; other site
768486005285	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
768486005286	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
768486005287	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
768486005288	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486005289	dimer interface [polypeptide binding]; other site
768486005290	conserved gate region; other site
768486005291	ABC-ATPase subunit interface; other site
768486005292	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
768486005293	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486005294	dimer interface [polypeptide binding]; other site
768486005295	conserved gate region; other site
768486005296	putative PBP binding loops; other site
768486005297	ABC-ATPase subunit interface; other site
768486005298	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
768486005299	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
768486005300	Domain of unknown function (DUF3502); Region: DUF3502; pfam12010
768486005301	N-terminal catalytic domain of endoplasmic reticulum(ER)/cytosolic class II alpha-mannosidases; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_ER_cytosolic; cd10789
768486005302	active site
768486005303	catalytic site [active]
768486005304	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; pfam09261
768486005305	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
768486005306	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
768486005307	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
768486005308	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
768486005309	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
768486005310	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
768486005311	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
768486005312	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
768486005313	Glycosyl hydrolase family 20 (GH20) catalytic domain of dispersin B (DspB), lacto-N-biosidase (LnbB) and related proteins. Dispersin B is a soluble beta-N-acetylglucosamidase found in bacteria that hydrolyzes the beta-1,6-linkages of PGA (poly-beta-(1,6)...; Region: GH20_DspB_LnbB-like; cd06564
768486005314	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
768486005315	active site
768486005316	hypothetical protein; Provisional; Region: PRK11770
768486005317	Domain of unknown function (DUF307); Region: DUF307; pfam03733
768486005318	Predicted transcriptional regulators [Transcription]; Region: COG1695
768486005319	Transcriptional regulator PadR-like family; Region: PadR; cl17335
768486005320	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486005321	Major Facilitator Superfamily; Region: MFS_1; pfam07690
768486005322	putative substrate translocation pore; other site
768486005323	Restriction endonuclease; Region: Mrr_cat; pfam04471
768486005324	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
768486005325	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
768486005326	FeS/SAM binding site; other site
768486005327	HemN C-terminal domain; Region: HemN_C; pfam06969
768486005328	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
768486005329	Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444
768486005330	GrpE; Region: GrpE; pfam01025
768486005331	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
768486005332	dimer interface [polypeptide binding]; other site
768486005333	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
768486005334	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
768486005335	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
768486005336	nucleotide binding site [chemical binding]; other site
768486005337	NEF interaction site [polypeptide binding]; other site
768486005338	SBD interface [polypeptide binding]; other site
768486005339	chaperone protein DnaJ; Provisional; Region: PRK14276
768486005340	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
768486005341	HSP70 interaction site [polypeptide binding]; other site
768486005342	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
768486005343	substrate binding site [polypeptide binding]; other site
768486005344	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
768486005345	Zn binding sites [ion binding]; other site
768486005346	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
768486005347	dimer interface [polypeptide binding]; other site
768486005348	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
768486005349	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
768486005350	Walker A/P-loop; other site
768486005351	ATP binding site [chemical binding]; other site
768486005352	Q-loop/lid; other site
768486005353	ABC transporter signature motif; other site
768486005354	Walker B; other site
768486005355	D-loop; other site
768486005356	H-loop/switch region; other site
768486005357	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
768486005358	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
768486005359	substrate binding pocket [chemical binding]; other site
768486005360	membrane-bound complex binding site; other site
768486005361	hinge residues; other site
768486005362	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486005363	dimer interface [polypeptide binding]; other site
768486005364	conserved gate region; other site
768486005365	ABC-ATPase subunit interface; other site
768486005366	excinuclease ABC subunit B; Provisional; Region: PRK05298
768486005367	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
768486005368	ATP binding site [chemical binding]; other site
768486005369	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
768486005370	nucleotide binding region [chemical binding]; other site
768486005371	ATP-binding site [chemical binding]; other site
768486005372	Ultra-violet resistance protein B; Region: UvrB; pfam12344
768486005373	UvrB/uvrC motif; Region: UVR; pfam02151
768486005374	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
768486005375	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
768486005376	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
768486005377	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
768486005378	Predicted ATP-grasp enzyme [General function prediction only]; Region: COG3919
768486005379	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
768486005380	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
768486005381	aspartate racemase; Region: asp_race; TIGR00035
768486005382	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
768486005383	AAA domain; Region: AAA_18; pfam13238
768486005384	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
768486005385	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
768486005386	phosphate binding site [ion binding]; other site
768486005387	putative substrate binding pocket [chemical binding]; other site
768486005388	dimer interface [polypeptide binding]; other site
768486005389	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
768486005390	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
768486005391	Thioredoxin; Region: Thioredoxin_4; pfam13462
768486005392	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
768486005393	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
768486005394	dimer interface [polypeptide binding]; other site
768486005395	PYR/PP interface [polypeptide binding]; other site
768486005396	TPP binding site [chemical binding]; other site
768486005397	substrate binding site [chemical binding]; other site
768486005398	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
768486005399	Domain of unknown function; Region: EKR; pfam10371
768486005400	4Fe-4S binding domain; Region: Fer4_6; pfam12837
768486005401	4Fe-4S binding domain; Region: Fer4; pfam00037
768486005402	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
768486005403	TPP-binding site [chemical binding]; other site
768486005404	dimer interface [polypeptide binding]; other site
768486005405	Uncharacterized conserved protein [Function unknown]; Region: COG1624
768486005406	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
768486005407	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
768486005408	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
768486005409	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
768486005410	active site
768486005411	substrate binding site [chemical binding]; other site
768486005412	metal binding site [ion binding]; metal-binding site
768486005413	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
768486005414	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
768486005415	Interdomain contacts; other site
768486005416	Cytokine receptor motif; other site
768486005417	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
768486005418	Interdomain contacts; other site
768486005419	Cytokine receptor motif; other site
768486005420	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
768486005421	Interdomain contacts; other site
768486005422	Cytokine receptor motif; other site
768486005423	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
768486005424	Interdomain contacts; other site
768486005425	Cytokine receptor motif; other site
768486005426	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
768486005427	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
768486005428	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
768486005429	glutaminase active site [active]
768486005430	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
768486005431	dimer interface [polypeptide binding]; other site
768486005432	active site
768486005433	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
768486005434	dimer interface [polypeptide binding]; other site
768486005435	active site
768486005436	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
768486005437	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
768486005438	tandem repeat interface [polypeptide binding]; other site
768486005439	oligomer interface [polypeptide binding]; other site
768486005440	active site residues [active]
768486005441	RDD family; Region: RDD; pfam06271
768486005442	trigger factor; Provisional; Region: tig; PRK01490
768486005443	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
768486005444	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
768486005445	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
768486005446	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
768486005447	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486005448	Walker A motif; other site
768486005449	ATP binding site [chemical binding]; other site
768486005450	Walker B motif; other site
768486005451	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
768486005452	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
768486005453	G1 box; other site
768486005454	GTP/Mg2+ binding site [chemical binding]; other site
768486005455	Switch I region; other site
768486005456	G2 box; other site
768486005457	G3 box; other site
768486005458	Switch II region; other site
768486005459	G4 box; other site
768486005460	G5 box; other site
768486005461	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
768486005462	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
768486005463	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
768486005464	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
768486005465	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
768486005466	putative substrate binding site [chemical binding]; other site
768486005467	putative ATP binding site [chemical binding]; other site
768486005468	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
768486005469	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
768486005470	active site
768486005471	phosphorylation site [posttranslational modification]
768486005472	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
768486005473	active site
768486005474	P-loop; other site
768486005475	phosphorylation site [posttranslational modification]
768486005476	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
768486005477	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
768486005478	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
768486005479	Cl- selectivity filter; other site
768486005480	Cl- binding residues [ion binding]; other site
768486005481	pore gating glutamate residue; other site
768486005482	dimer interface [polypeptide binding]; other site
768486005483	H+/Cl- coupling transport residue; other site
768486005484	TrkA-C domain; Region: TrkA_C; pfam02080
768486005485	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
768486005486	Part of AAA domain; Region: AAA_19; pfam13245
768486005487	Family description; Region: UvrD_C_2; pfam13538
768486005488	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
768486005489	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
768486005490	nucleotide binding pocket [chemical binding]; other site
768486005491	K-X-D-G motif; other site
768486005492	catalytic site [active]
768486005493	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
768486005494	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
768486005495	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
768486005496	Dimer interface [polypeptide binding]; other site
768486005497	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
768486005498	potential frameshift: common BLAST hit: gi|29375321|ref|NP_814475.1| glutamyl-tRNA(Gln) amidotransferase, A subunit
768486005499	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
768486005500	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
768486005501	GatB domain; Region: GatB_Yqey; smart00845
768486005502	putative lipid kinase; Reviewed; Region: PRK13055
768486005503	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
768486005504	TRAM domain; Region: TRAM; cl01282
768486005505	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
768486005506	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486005507	S-adenosylmethionine binding site [chemical binding]; other site
768486005508	Mga helix-turn-helix domain; Region: Mga; pfam05043
768486005509	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
768486005510	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486005511	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
768486005512	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486005513	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486005514	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486005515	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
768486005516	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
768486005517	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
768486005518	potential frameshift: common BLAST hit: gi|389869712|ref|YP_006377135.1| glycosyl hydrolase
768486005519	BNR repeat-like domain; Region: BNR_2; pfam13088
768486005520	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
768486005521	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
768486005522	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486005523	Walker A/P-loop; other site
768486005524	ATP binding site [chemical binding]; other site
768486005525	Q-loop/lid; other site
768486005526	ABC transporter signature motif; other site
768486005527	Walker B; other site
768486005528	D-loop; other site
768486005529	H-loop/switch region; other site
768486005530	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
768486005531	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
768486005532	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486005533	Walker A/P-loop; other site
768486005534	ATP binding site [chemical binding]; other site
768486005535	Q-loop/lid; other site
768486005536	ABC transporter signature motif; other site
768486005537	Walker B; other site
768486005538	D-loop; other site
768486005539	H-loop/switch region; other site
768486005540	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
768486005541	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
768486005542	DNA binding residues [nucleotide binding]
768486005543	dimer interface [polypeptide binding]; other site
768486005544	Transcriptional regulators [Transcription]; Region: PurR; COG1609
768486005545	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
768486005546	DNA binding site [nucleotide binding]
768486005547	domain linker motif; other site
768486005548	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
768486005549	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
768486005550	Melibiase; Region: Melibiase; pfam02065
768486005551	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
768486005552	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
768486005553	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
768486005554	potential frameshift: common BLAST hit: gi|338203848|ref|YP_004649993.1| beta-galactosidase small subunit
768486005555	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
768486005556	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
768486005557	Histidine kinase; Region: His_kinase; pfam06580
768486005558	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
768486005559	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms]; Region: COG4753
768486005560	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486005561	active site
768486005562	phosphorylation site [posttranslational modification]
768486005563	intermolecular recognition site; other site
768486005564	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
768486005565	potential frameshift: common BLAST hit: gi|332686484|ref|YP_004456258.1| alpha-arabinosides ABC transporter permease AraN
768486005566	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486005567	dimer interface [polypeptide binding]; other site
768486005568	conserved gate region; other site
768486005569	putative PBP binding loops; other site
768486005570	ABC-ATPase subunit interface; other site
768486005571	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
768486005572	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486005573	dimer interface [polypeptide binding]; other site
768486005574	conserved gate region; other site
768486005575	putative PBP binding loops; other site
768486005576	ABC-ATPase subunit interface; other site
768486005577	Viral enhancin protein; Region: Enhancin; pfam03272
768486005578	Peptidase M60-like family; Region: M60-like; pfam13402
768486005579	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
768486005580	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
768486005581	YSIRK-targeted surface antigen transcriptional regulator; Region: adjacent_YSIRK; TIGR04094
768486005582	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
768486005583	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
768486005584	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
768486005585	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
768486005586	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
768486005587	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
768486005588	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
768486005589	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
768486005590	beta-galactosidase; Region: BGL; TIGR03356
768486005591	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
768486005592	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
768486005593	Domain of unknown function (DUF4091); Region: DUF4091; pfam13320
768486005594	Protein of unknown function (DUF1538); Region: DUF1538; pfam07556
768486005595	Protein of unknown function (DUF1538); Region: DUF1538; pfam07556
768486005596	Nitrogen regulatory protein P-II; Region: P-II; smart00938
768486005597	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
768486005598	catalytic core [active]
768486005599	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
768486005600	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
768486005601	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486005602	motif II; other site
768486005603	Protein of unknown function (DUF1149); Region: DUF1149; cl11551
768486005604	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
768486005605	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
768486005606	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
768486005607	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
768486005608	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
768486005609	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
768486005610	active site residue [active]
768486005611	Protein of unknown function (DUF3650); Region: DUF3650; pfam12368
768486005612	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
768486005613	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
768486005614	active site
768486005615	metal binding site [ion binding]; metal-binding site
768486005616	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
768486005617	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
768486005618	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
768486005619	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
768486005620	RNA binding site [nucleotide binding]; other site
768486005621	SprT homologues; Region: SprT; cl01182
768486005622	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
768486005623	putative active site [active]
768486005624	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
768486005625	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
768486005626	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
768486005627	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
768486005628	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
768486005629	active site 2 [active]
768486005630	active site 1 [active]
768486005631	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
768486005632	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
768486005633	potential frameshift: common BLAST hit: gi|29375463|ref|NP_814617.1| DNA polymerase I
768486005634	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
768486005635	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
768486005636	DNA binding site [nucleotide binding]
768486005637	catalytic residue [active]
768486005638	H2TH interface [polypeptide binding]; other site
768486005639	putative catalytic residues [active]
768486005640	turnover-facilitating residue; other site
768486005641	intercalation triad [nucleotide binding]; other site
768486005642	8OG recognition residue [nucleotide binding]; other site
768486005643	putative reading head residues; other site
768486005644	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
768486005645	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
768486005646	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
768486005647	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
768486005648	CoA-binding site [chemical binding]; other site
768486005649	ATP-binding [chemical binding]; other site
768486005650	potential frameshift: common BLAST hit: gi|29375466|ref|NP_814620.1| transcriptional regulator NrdR
768486005651	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
768486005652	Replication initiation and membrane attachment; Region: DnaB_2; cl12121
768486005653	potential frameshift: common BLAST hit: gi|29375468|ref|NP_814622.1| primosomal protein DnaI
768486005654	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
768486005655	Family of unknown function (DUF633); Region: DUF633; pfam04816
768486005656	Uncharacterized conserved protein [Function unknown]; Region: COG0327
768486005657	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
768486005658	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
768486005659	Uncharacterized conserved protein [Function unknown]; Region: COG0327
768486005660	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
768486005661	peptidase T; Region: peptidase-T; TIGR01882
768486005662	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
768486005663	metal binding site [ion binding]; metal-binding site
768486005664	dimer interface [polypeptide binding]; other site
768486005665	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
768486005666	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
768486005667	Protein of unknown function (DUF1294); Region: DUF1294; pfam06961
768486005668	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
768486005669	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
768486005670	Clp amino terminal domain; Region: Clp_N; pfam02861
768486005671	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486005672	Walker A motif; other site
768486005673	ATP binding site [chemical binding]; other site
768486005674	Walker B motif; other site
768486005675	arginine finger; other site
768486005676	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486005677	Walker A motif; other site
768486005678	ATP binding site [chemical binding]; other site
768486005679	Walker B motif; other site
768486005680	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
768486005681	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; pfam05014
768486005682	hypothetical protein; Provisional; Region: PRK01346
768486005683	Acetyltransferase (GNAT) domain; Region: Acetyltransf_9; pfam13527
768486005684	Sterol carrier protein domain; Region: SCP2_2; pfam13530
768486005685	GTP-binding protein LepA; Provisional; Region: PRK05433
768486005686	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
768486005687	G1 box; other site
768486005688	putative GEF interaction site [polypeptide binding]; other site
768486005689	GTP/Mg2+ binding site [chemical binding]; other site
768486005690	Switch I region; other site
768486005691	G2 box; other site
768486005692	G3 box; other site
768486005693	Switch II region; other site
768486005694	G4 box; other site
768486005695	G5 box; other site
768486005696	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
768486005697	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
768486005698	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
768486005699	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
768486005700	DNA-binding site [nucleotide binding]; DNA binding site
768486005701	RNA-binding motif; other site
768486005702	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
768486005703	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
768486005704	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
768486005705	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
768486005706	Uncharacterized conserved protein [Function unknown]; Region: COG3589
768486005707	Uncharacterized conserved protein [Function unknown]; Region: COG3589
768486005708	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
768486005709	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
768486005710	nucleotide binding site [chemical binding]; other site
768486005711	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
768486005712	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
768486005713	S-formylglutathione hydrolase; Region: PLN02442
768486005714	Putative esterase; Region: Esterase; pfam00756
768486005715	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
768486005716	beta-galactosidase; Region: BGL; TIGR03356
768486005717	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
768486005718	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
768486005719	nucleotide binding site [chemical binding]; other site
768486005720	Domain of unknown function (DUF4352); Region: DUF4352; pfam11611
768486005721	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
768486005722	DNA-binding site [nucleotide binding]; DNA binding site
768486005723	RNA-binding motif; other site
768486005724	conserved hypothetical protein; Region: TIGR02328
768486005725	Pyrimidine dimer DNA glycosylase; Region: Pyr_excise; pfam03013
768486005726	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486005727	sequence-specific DNA binding site [nucleotide binding]; other site
768486005728	salt bridge; other site
768486005729	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
768486005730	catalytic triad [active]
768486005731	conserved cis-peptide bond; other site
768486005732	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486005733	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
768486005734	active site
768486005735	motif I; other site
768486005736	motif II; other site
768486005737	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486005738	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
768486005739	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
768486005740	Ligand binding site; other site
768486005741	metal-binding site
768486005742	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
768486005743	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
768486005744	Ligand binding site; other site
768486005745	metal-binding site
768486005746	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
768486005747	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
768486005748	Cl binding site [ion binding]; other site
768486005749	oligomer interface [polypeptide binding]; other site
768486005750	oxidoreductase; Provisional; Region: PRK07985
768486005751	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
768486005752	NAD(P) binding site [chemical binding]; other site
768486005753	active site
768486005754	Small integral membrane protein (DUF2273); Region: DUF2273; cl11575
768486005755	Asp23 family; Region: Asp23; pfam03780
768486005756	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
768486005757	Rib/alpha-like repeat; Region: Rib; cl07159
768486005758	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
768486005759	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486005760	salt bridge; other site
768486005761	non-specific DNA binding site [nucleotide binding]; other site
768486005762	sequence-specific DNA binding site [nucleotide binding]; other site
768486005763	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
768486005764	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
768486005765	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
768486005766	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486005767	active site
768486005768	phosphorylation site [posttranslational modification]
768486005769	intermolecular recognition site; other site
768486005770	dimerization interface [polypeptide binding]; other site
768486005771	LytTr DNA-binding domain; Region: LytTR; pfam04397
768486005772	Accessory gene regulator B; Region: AgrB; pfam04647
768486005773	Staphylococcal AgrD protein; Region: AgrD; cl05477
768486005774	Small integral membrane protein (DUF2273); Region: DUF2273; cl11575
768486005775	Asp23 family; Region: Asp23; pfam03780
768486005776	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
768486005777	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
768486005778	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
768486005779	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
768486005780	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
768486005781	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK12315
768486005782	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
768486005783	TPP-binding site; other site
768486005784	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
768486005785	PYR/PP interface [polypeptide binding]; other site
768486005786	dimer interface [polypeptide binding]; other site
768486005787	TPP binding site [chemical binding]; other site
768486005788	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
768486005789	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cl00022
768486005790	putative deacylase active site [active]
768486005791	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
768486005792	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
768486005793	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
768486005794	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
768486005795	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
768486005796	Cell cycle protein; Region: FTSW_RODA_SPOVE; pfam01098
768486005797	Transcriptional regulator [Transcription]; Region: LytR; COG1316
768486005798	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
768486005799	NTF2-like N-terminal transpeptidase domain; Region: MecA_N; pfam05223
768486005800	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
768486005801	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
768486005802	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486005803	Major Facilitator Superfamily; Region: MFS_1; pfam07690
768486005804	putative substrate translocation pore; other site
768486005805	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
768486005806	MarR family; Region: MarR; pfam01047
768486005807	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
768486005808	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
768486005809	Short repeat of unknown function (DUF308); Region: DUF308; pfam03729
768486005810	Uncharacterized protein conserved in bacteria (DUF2200); Region: DUF2200; pfam09966
768486005811	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
768486005812	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
768486005813	catalytic residue [active]
768486005814	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
768486005815	catalytic residues [active]
768486005816	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
768486005817	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
768486005818	peroxiredoxin; Region: AhpC; TIGR03137
768486005819	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
768486005820	dimer interface [polypeptide binding]; other site
768486005821	decamer (pentamer of dimers) interface [polypeptide binding]; other site
768486005822	catalytic triad [active]
768486005823	peroxidatic and resolving cysteines [active]
768486005824	potential frameshift: common BLAST hit: gi|389868630|ref|YP_006376053.1| transcriptional regulator
768486005825	Protein of unknown function (DUF2552); Region: DUF2552; pfam10827
768486005826	Mga helix-turn-helix domain; Region: Mga; pfam05043
768486005827	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
768486005828	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
768486005829	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
768486005830	active site
768486005831	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
768486005832	MarR family; Region: MarR; pfam01047
768486005833	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
768486005834	Uncharacterized conserved protein [Function unknown]; Region: COG1284
768486005835	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
768486005836	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
768486005837	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
768486005838	CoenzymeA binding site [chemical binding]; other site
768486005839	subunit interaction site [polypeptide binding]; other site
768486005840	PHB binding site; other site
768486005841	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
768486005842	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
768486005843	substrate binding site [chemical binding]; other site
768486005844	oxyanion hole (OAH) forming residues; other site
768486005845	trimer interface [polypeptide binding]; other site
768486005846	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK03640
768486005847	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
768486005848	acyl-activating enzyme (AAE) consensus motif; other site
768486005849	putative AMP binding site [chemical binding]; other site
768486005850	putative active site [active]
768486005851	putative CoA binding site [chemical binding]; other site
768486005852	Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: MenF; COG1169
768486005853	chorismate binding enzyme; Region: Chorismate_bind; cl10555
768486005854	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
768486005855	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
768486005856	dimer interface [polypeptide binding]; other site
768486005857	tetramer interface [polypeptide binding]; other site
768486005858	PYR/PP interface [polypeptide binding]; other site
768486005859	TPP binding site [chemical binding]; other site
768486005860	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
768486005861	TPP-binding site; other site
768486005862	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
768486005863	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Region: menH_SHCHC; TIGR03695
768486005864	N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building...; Region: NAAAR; cd03317
768486005865	o-succinylbenzoate synthase; Region: menC_lowGC/arch; TIGR01928
768486005866	active site
768486005867	octamer interface [polypeptide binding]; other site
768486005868	maltodextrin glucosidase; Provisional; Region: PRK10785
768486005869	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
768486005870	homodimer interface [polypeptide binding]; other site
768486005871	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
768486005872	active site
768486005873	homodimer interface [polypeptide binding]; other site
768486005874	catalytic site [active]
768486005875	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
768486005876	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
768486005877	potential frameshift: common BLAST hit: gi|116873560|ref|YP_850341.1| maltose/maltodextrin ABC transporter, permease protein
768486005878	potential frameshift: common BLAST hit: gi|328957685|ref|YP_004375071.1| maltodextrin ABC transport system
768486005879	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
768486005880	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486005881	dimer interface [polypeptide binding]; other site
768486005882	conserved gate region; other site
768486005883	putative PBP binding loops; other site
768486005884	ABC-ATPase subunit interface; other site
768486005885	Predicted integral membrane protein [Function unknown]; Region: COG5521
768486005886	Predicted integral membrane protein [Function unknown]; Region: COG5521
768486005887	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
768486005888	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486005889	S-adenosylmethionine binding site [chemical binding]; other site
768486005890	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
768486005891	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
768486005892	SLBB domain; Region: SLBB; pfam10531
768486005893	Glycine/sarcosine/betaine reductase component B subunits; Region: Gly_reductase; pfam09338
768486005894	potential frameshift: common BLAST hit: gi|260688442|ref|YP_003219576.1| proline reductase
768486005895	Glycine/sarcosine/betaine reductase component B subunits; Region: Gly_reductase; pfam09338
768486005896	proline racemase; Provisional; Region: PRK13969
768486005897	hydroxyproline-2-epimerase; Provisional; Region: PRK13971
768486005898	selenium donor protein; Region: selD; TIGR00476
768486005899	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
768486005900	dimerization interface [polypeptide binding]; other site
768486005901	putative ATP binding site [chemical binding]; other site
768486005902	SirA_like_N, a protein of unknown function with an N-terminal SirA-like domain.  The SirA, YedF, YeeD protein family is present in bacteria as well as archaea. SirA (also known as UvrY,  and YhhP) belongs to a family of a two-component response...; Region: SirA_like_N; cd03421
768486005903	selenium metabolism protein YedF; Region: selenium_YedF; TIGR03527
768486005904	CPxP  motif; other site
768486005905	DsrE/DsrF-like family; Region: DrsE; pfam02635
768486005906	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
768486005907	Selenocysteine-specific translation elongation factor [Translation, ribosomal structure and biogenesis]; Region: SelB; COG3276
768486005908	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
768486005909	G1 box; other site
768486005910	putative GEF interaction site [polypeptide binding]; other site
768486005911	GTP/Mg2+ binding site [chemical binding]; other site
768486005912	Switch I region; other site
768486005913	G2 box; other site
768486005914	G3 box; other site
768486005915	Switch II region; other site
768486005916	G4 box; other site
768486005917	G5 box; other site
768486005918	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
768486005919	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
768486005920	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
768486005921	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
768486005922	potential frameshift: common BLAST hit: gi|260687733|ref|YP_003218867.1| selenocysteine-specific elongation factor
768486005923	potential frameshift: common BLAST hit: gi|260687733|ref|YP_003218867.1| selenocysteine-specific elongation factor
768486005924	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
768486005925	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
768486005926	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
768486005927	catalytic residue [active]
768486005928	selenocysteine synthase; Provisional; Region: PRK04311
768486005929	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
768486005930	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
768486005931	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
768486005932	catalytic residue [active]
768486005933	seryl-tRNA(sec) selenium transferase; Region: selA; TIGR00474
768486005934	Protein of unknown function (DUF523); Region: DUF523; cl00733
768486005935	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
768486005936	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486005937	Walker A/P-loop; other site
768486005938	ATP binding site [chemical binding]; other site
768486005939	Q-loop/lid; other site
768486005940	ABC transporter signature motif; other site
768486005941	Walker B; other site
768486005942	D-loop; other site
768486005943	H-loop/switch region; other site
768486005944	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486005945	dimer interface [polypeptide binding]; other site
768486005946	conserved gate region; other site
768486005947	putative PBP binding loops; other site
768486005948	ABC-ATPase subunit interface; other site
768486005949	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
768486005950	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
768486005951	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
768486005952	Predicted membrane protein [Function unknown]; Region: COG3212
768486005953	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
768486005954	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
768486005955	Dihydroorotate dehydrogenase (DHOD) class 1A FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1A_like; cd04741
768486005956	active site
768486005957	FMN binding site [chemical binding]; other site
768486005958	substrate binding site [chemical binding]; other site
768486005959	catalytic residues [active]
768486005960	homodimer interface [polypeptide binding]; other site
768486005961	amidase; Provisional; Region: PRK06529
768486005962	Amidase; Region: Amidase; cl11426
768486005963	Guanylate kinase; Region: Guanylate_kin; pfam00625
768486005964	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
768486005965	catalytic site [active]
768486005966	G-X2-G-X-G-K; other site
768486005967	potential frameshift: common BLAST hit: gi|389868606|ref|YP_006376029.1| CNT family concentrative nucleoside transporter
768486005968	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
768486005969	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
768486005970	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4868
768486005971	Domain of unknown function (DUF1846); Region: DUF1846; pfam08903
768486005972	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
768486005973	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
768486005974	Cation efflux family; Region: Cation_efflux; pfam01545
768486005975	AzlC protein; Region: AzlC; pfam03591
768486005976	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
768486005977	stage V sporulation protein B; Region: spore_V_B; TIGR02900
768486005978	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
768486005979	EDD domain protein, DegV family; Region: DegV; TIGR00762
768486005980	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
768486005981	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
768486005982	norD type: Denitrifying bacteria contain both membrane bound and periplasmic nitrate reductases. Denitrification plays a major role  in completing the nitrogen cycle by converting nitrate or nitrite to nitrogen gas. The pathway for microbial...; Region: vWA_norD_type; cd01454
768486005983	metal ion-dependent adhesion site (MIDAS); other site
768486005984	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
768486005985	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
768486005986	Ca binding site [ion binding]; other site
768486005987	active site
768486005988	catalytic site [active]
768486005989	Protein of unknown function (DUF436); Region: DUF436; pfam04260
768486005990	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; pfam07155
768486005991	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
768486005992	dimer interface [polypeptide binding]; other site
768486005993	substrate binding site [chemical binding]; other site
768486005994	ATP binding site [chemical binding]; other site
768486005995	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
768486005996	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
768486005997	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
768486005998	acyl-activating enzyme (AAE) consensus motif; other site
768486005999	acyl-activating enzyme (AAE) consensus motif; other site
768486006000	AMP binding site [chemical binding]; other site
768486006001	active site
768486006002	CoA binding site [chemical binding]; other site
768486006003	site-specific tyrosine recombinase XerS; Reviewed; Region: xerS; PRK05084
768486006004	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
768486006005	DNA binding site [nucleotide binding]
768486006006	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
768486006007	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
768486006008	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
768486006009	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
768486006010	Walker A/P-loop; other site
768486006011	ATP binding site [chemical binding]; other site
768486006012	Q-loop/lid; other site
768486006013	ABC transporter signature motif; other site
768486006014	Walker B; other site
768486006015	D-loop; other site
768486006016	H-loop/switch region; other site
768486006017	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
768486006018	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
768486006019	active site
768486006020	catalytic triad [active]
768486006021	oxyanion hole [active]
768486006022	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
768486006023	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
768486006024	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
768486006025	putative active site [active]
768486006026	putative oxidoreductase; Provisional; Region: PRK10206
768486006027	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
768486006028	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
768486006029	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
768486006030	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
768486006031	tetramer (dimer of dimers) interface [polypeptide binding]; other site
768486006032	NAD binding site [chemical binding]; other site
768486006033	dimer interface [polypeptide binding]; other site
768486006034	substrate binding site [chemical binding]; other site
768486006035	DNA topoisomerase III; Provisional; Region: PRK07726
768486006036	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
768486006037	active site
768486006038	putative interdomain interaction site [polypeptide binding]; other site
768486006039	putative metal-binding site [ion binding]; other site
768486006040	putative nucleotide binding site [chemical binding]; other site
768486006041	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
768486006042	domain I; other site
768486006043	DNA binding groove [nucleotide binding]
768486006044	phosphate binding site [ion binding]; other site
768486006045	domain II; other site
768486006046	domain III; other site
768486006047	nucleotide binding site [chemical binding]; other site
768486006048	catalytic site [active]
768486006049	domain IV; other site
768486006050	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
768486006051	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; pfam03816
768486006052	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
768486006053	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
768486006054	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
768486006055	shikimate binding site; other site
768486006056	NAD(P) binding site [chemical binding]; other site
768486006057	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
768486006058	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486006059	Walker A/P-loop; other site
768486006060	ATP binding site [chemical binding]; other site
768486006061	Q-loop/lid; other site
768486006062	ABC transporter signature motif; other site
768486006063	Walker B; other site
768486006064	D-loop; other site
768486006065	H-loop/switch region; other site
768486006066	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
768486006067	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
768486006068	TM-ABC transporter signature motif; other site
768486006069	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
768486006070	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
768486006071	zinc binding site [ion binding]; other site
768486006072	putative ligand binding site [chemical binding]; other site
768486006073	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
768486006074	Domain of unknown function (DUF814); Region: DUF814; pfam05670
768486006075	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
768486006076	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
768486006077	ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism]; Region: AbcD; COG2011
768486006078	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486006079	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
768486006080	Walker A/P-loop; other site
768486006081	ATP binding site [chemical binding]; other site
768486006082	Q-loop/lid; other site
768486006083	ABC transporter signature motif; other site
768486006084	Walker B; other site
768486006085	D-loop; other site
768486006086	H-loop/switch region; other site
768486006087	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
768486006088	Transcriptional regulator [Transcription]; Region: LysR; COG0583
768486006089	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
768486006090	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
768486006091	dimerization interface [polypeptide binding]; other site
768486006092	potential frameshift: common BLAST hit: gi|29376263|ref|NP_815417.1| carbonic anhydrase
768486006093	HD domain; Region: HD_3; cl17350
768486006094	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
768486006095	active site
768486006096	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
768486006097	active site
768486006098	dimer interface [polypeptide binding]; other site
768486006099	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
768486006100	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
768486006101	heterodimer interface [polypeptide binding]; other site
768486006102	active site
768486006103	FMN binding site [chemical binding]; other site
768486006104	homodimer interface [polypeptide binding]; other site
768486006105	substrate binding site [chemical binding]; other site
768486006106	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
768486006107	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
768486006108	FAD binding pocket [chemical binding]; other site
768486006109	FAD binding motif [chemical binding]; other site
768486006110	phosphate binding motif [ion binding]; other site
768486006111	beta-alpha-beta structure motif; other site
768486006112	NAD binding pocket [chemical binding]; other site
768486006113	Iron coordination center [ion binding]; other site
768486006114	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
768486006115	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
768486006116	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
768486006117	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
768486006118	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
768486006119	ATP-grasp domain; Region: ATP-grasp_4; cl17255
768486006120	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
768486006121	IMP binding site; other site
768486006122	dimer interface [polypeptide binding]; other site
768486006123	interdomain contacts; other site
768486006124	partial ornithine binding site; other site
768486006125	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
768486006126	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
768486006127	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
768486006128	catalytic site [active]
768486006129	subunit interface [polypeptide binding]; other site
768486006130	dihydroorotase; Validated; Region: pyrC; PRK09357
768486006131	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
768486006132	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
768486006133	active site
768486006134	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
768486006135	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
768486006136	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
768486006137	uracil transporter; Provisional; Region: PRK10720
768486006138	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
768486006139	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
768486006140	active site
768486006141	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
768486006142	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
768486006143	RNA binding surface [nucleotide binding]; other site
768486006144	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
768486006145	active site
768486006146	lipoprotein signal peptidase; Provisional; Region: PRK14797
768486006147	lipoprotein signal peptidase; Provisional; Region: PRK14787
768486006148	Predicted transcriptional regulator with C-terminal CBS domains [Transcription]; Region: COG3620
768486006149	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
768486006150	CAAX protease self-immunity; Region: Abi; pfam02517
768486006151	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
768486006152	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
768486006153	Potassium binding sites [ion binding]; other site
768486006154	Cesium cation binding sites [ion binding]; other site
768486006155	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
768486006156	DNA-binding site [nucleotide binding]; DNA binding site
768486006157	RNA-binding motif; other site
768486006158	RNAse HI family that includes Archaeal RNase HI; Region: RNase_HI_archaeal_like; cd09279
768486006159	RNA/DNA hybrid binding site [nucleotide binding]; other site
768486006160	active site
768486006161	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
768486006162	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
768486006163	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
768486006164	Predicted membrane protein [Function unknown]; Region: COG4684
768486006165	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
768486006166	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
768486006167	motif 1; other site
768486006168	active site
768486006169	motif 2; other site
768486006170	motif 3; other site
768486006171	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
768486006172	DHHA1 domain; Region: DHHA1; pfam02272
768486006173	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
768486006174	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486006175	Coenzyme A binding pocket [chemical binding]; other site
768486006176	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
768486006177	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
768486006178	ATP binding site [chemical binding]; other site
768486006179	Mg++ binding site [ion binding]; other site
768486006180	motif III; other site
768486006181	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
768486006182	nucleotide binding region [chemical binding]; other site
768486006183	ATP-binding site [chemical binding]; other site
768486006184	potential frameshift: common BLAST hit: gi|389868517|ref|YP_006375940.1| VanZ/RDD domain protein
768486006185	VanZ like family; Region: VanZ; pfam04892
768486006186	RDD family; Region: RDD; pfam06271
768486006187	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
768486006188	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
768486006189	L-threonine dehydrogenase, extended (e) SDRs; Region: TDH_SDR_e; cd05272
768486006190	NAD binding site [chemical binding]; other site
768486006191	homodimer interface [polypeptide binding]; other site
768486006192	active site
768486006193	putative substrate binding site [chemical binding]; other site
768486006194	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
768486006195	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
768486006196	substrate-cofactor binding pocket; other site
768486006197	pyridoxal 5'-phosphate binding site [chemical binding]; other site
768486006198	catalytic residue [active]
768486006199	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
768486006200	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
768486006201	Zn2+ binding site [ion binding]; other site
768486006202	Mg2+ binding site [ion binding]; other site
768486006203	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
768486006204	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
768486006205	active site
768486006206	Zn binding site [ion binding]; other site
768486006207	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
768486006208	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
768486006209	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
768486006210	cell division protein GpsB; Provisional; Region: PRK14127
768486006211	DivIVA domain; Region: DivI1A_domain; TIGR03544
768486006212	hypothetical protein; Provisional; Region: PRK13660
768486006213	Holliday junction-specific endonuclease; Reviewed; Region: recU; PRK02234
768486006214	Transglycosylase; Region: Transgly; pfam00912
768486006215	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
768486006216	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
768486006217	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
768486006218	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
768486006219	minor groove reading motif; other site
768486006220	helix-hairpin-helix signature motif; other site
768486006221	substrate binding pocket [chemical binding]; other site
768486006222	active site
768486006223	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
768486006224	Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935
768486006225	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
768486006226	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
768486006227	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
768486006228	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
768486006229	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
768486006230	metal binding site 2 [ion binding]; metal-binding site
768486006231	putative DNA binding helix; other site
768486006232	metal binding site 1 [ion binding]; metal-binding site
768486006233	dimer interface [polypeptide binding]; other site
768486006234	structural Zn2+ binding site [ion binding]; other site
768486006235	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
768486006236	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
768486006237	dimer interface [polypeptide binding]; other site
768486006238	pyridoxal 5'-phosphate binding site [chemical binding]; other site
768486006239	catalytic residue [active]
768486006240	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
768486006241	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
768486006242	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
768486006243	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
768486006244	TPP-binding site [chemical binding]; other site
768486006245	dimer interface [polypeptide binding]; other site
768486006246	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
768486006247	PYR/PP interface [polypeptide binding]; other site
768486006248	dimer interface [polypeptide binding]; other site
768486006249	TPP binding site [chemical binding]; other site
768486006250	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
768486006251	hypothetical protein; Provisional; Region: PRK02539
768486006252	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
768486006253	putative DNA binding site [nucleotide binding]; other site
768486006254	LexA repressor; Validated; Region: PRK00215
768486006255	putative Zn2+ binding site [ion binding]; other site
768486006256	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
768486006257	Catalytic site [active]
768486006258	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
768486006259	active site
768486006260	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
768486006261	DHH family; Region: DHH; pfam01368
768486006262	DHHA1 domain; Region: DHHA1; pfam02272
768486006263	Single-strand DNA-specific exonuclease, C terminal domain; Region: ssDNA-exonuc_C; cl11538
768486006264	Protein of unknown function (DUF1049); Region: DUF1049; cl01539
768486006265	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
768486006266	NAD(P) binding site [chemical binding]; other site
768486006267	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
768486006268	active site
768486006269	ribonuclease Z; Region: RNase_Z; TIGR02651
768486006270	GTPase CgtA; Reviewed; Region: obgE; PRK12297
768486006271	GTP1/OBG; Region: GTP1_OBG; pfam01018
768486006272	Obg GTPase; Region: Obg; cd01898
768486006273	G1 box; other site
768486006274	GTP/Mg2+ binding site [chemical binding]; other site
768486006275	Switch I region; other site
768486006276	G2 box; other site
768486006277	G3 box; other site
768486006278	Switch II region; other site
768486006279	G4 box; other site
768486006280	G5 box; other site
768486006281	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
768486006282	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
768486006283	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
768486006284	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
768486006285	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
768486006286	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
768486006287	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
768486006288	Uncharacterized conserved protein [Function unknown]; Region: COG3589
768486006289	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
768486006290	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
768486006291	active site
768486006292	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
768486006293	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK06079
768486006294	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
768486006295	NAD binding site [chemical binding]; other site
768486006296	homotetramer interface [polypeptide binding]; other site
768486006297	homodimer interface [polypeptide binding]; other site
768486006298	substrate binding site [chemical binding]; other site
768486006299	active site
768486006300	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
768486006301	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
768486006302	homodimer interface [polypeptide binding]; other site
768486006303	substrate-cofactor binding pocket; other site
768486006304	catalytic residue [active]
768486006305	potential frameshift: common BLAST hit: gi|389868476|ref|YP_006375899.1| MscS family small conductance mechanosenstive ion channel protein
768486006306	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
768486006307	Mechanosensitive ion channel; Region: MS_channel; pfam00924
768486006308	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_30; cd04643
768486006309	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
768486006310	active site
768486006311	metal binding site [ion binding]; metal-binding site
768486006312	homotetramer interface [polypeptide binding]; other site
768486006313	ribonuclease PH; Reviewed; Region: rph; PRK00173
768486006314	Ribonuclease PH; Region: RNase_PH_bact; cd11362
768486006315	hexamer interface [polypeptide binding]; other site
768486006316	active site
768486006317	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
768486006318	active site
768486006319	dimerization interface [polypeptide binding]; other site
768486006320	glutamate racemase; Provisional; Region: PRK00865
768486006321	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
768486006322	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08115
768486006323	Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317
768486006324	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
768486006325	Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888
768486006326	active site
768486006327	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
768486006328	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486006329	dimer interface [polypeptide binding]; other site
768486006330	conserved gate region; other site
768486006331	putative PBP binding loops; other site
768486006332	ABC-ATPase subunit interface; other site
768486006333	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
768486006334	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486006335	dimer interface [polypeptide binding]; other site
768486006336	conserved gate region; other site
768486006337	putative PBP binding loops; other site
768486006338	ABC-ATPase subunit interface; other site
768486006339	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
768486006340	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
768486006341	substrate binding pocket [chemical binding]; other site
768486006342	membrane-bound complex binding site; other site
768486006343	hinge residues; other site
768486006344	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
768486006345	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
768486006346	Walker A/P-loop; other site
768486006347	ATP binding site [chemical binding]; other site
768486006348	Q-loop/lid; other site
768486006349	ABC transporter signature motif; other site
768486006350	Walker B; other site
768486006351	D-loop; other site
768486006352	H-loop/switch region; other site
768486006353	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
768486006354	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
768486006355	active site
768486006356	HIGH motif; other site
768486006357	dimer interface [polypeptide binding]; other site
768486006358	KMSKS motif; other site
768486006359	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
768486006360	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
768486006361	putative tRNA-binding site [nucleotide binding]; other site
768486006362	B3/4 domain; Region: B3_4; pfam03483
768486006363	tRNA synthetase B5 domain; Region: B5; smart00874
768486006364	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
768486006365	dimer interface [polypeptide binding]; other site
768486006366	motif 1; other site
768486006367	motif 3; other site
768486006368	motif 2; other site
768486006369	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
768486006370	potential frameshift: common BLAST hit: gi|383328358|ref|YP_005354242.1| phenylalanyl-tRNA synthetase subunit alpha
768486006371	phenylalanyl-tRNA synthetase, alpha subunit; Region: pheS; TIGR00468
768486006372	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
768486006373	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
768486006374	dimer interface [polypeptide binding]; other site
768486006375	motif 1; other site
768486006376	active site
768486006377	motif 2; other site
768486006378	motif 3; other site
768486006379	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
768486006380	Predicted transcriptional regulators [Transcription]; Region: COG1733
768486006381	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
768486006382	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
768486006383	Part of AAA domain; Region: AAA_19; pfam13245
768486006384	Family description; Region: UvrD_C_2; pfam13538
768486006385	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
768486006386	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
768486006387	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
768486006388	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486006389	putative substrate translocation pore; other site
768486006390	POT family; Region: PTR2; cl17359
768486006391	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
768486006392	dimer interface [polypeptide binding]; other site
768486006393	FMN binding site [chemical binding]; other site
768486006394	potential frameshift: common BLAST hit: gi|269202982|ref|YP_003282251.1| fmtC protein
768486006395	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39A; cd02549
768486006396	putative active site [active]
768486006397	Protein of unknown function (DUF1093); Region: DUF1093; pfam06486
768486006398	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
768486006399	Ligand Binding Site [chemical binding]; other site
768486006400	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
768486006401	Protein of unknown function (DUF1706); Region: DUF1706; cl01748
768486006402	Protein of unknown function (DUF1706); Region: DUF1706; cl01748
768486006403	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486006404	S-adenosylmethionine binding site [chemical binding]; other site
768486006405	Protein of unknown function (DUF2089); Region: DUF2089; pfam09862
768486006406	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
768486006407	Uncharacterized conserved protein [Function unknown]; Region: COG1284
768486006408	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
768486006409	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
768486006410	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
768486006411	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
768486006412	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
768486006413	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
768486006414	DEAD/DEAH box helicase; Region: DEAD; pfam00270
768486006415	DEAD_2; Region: DEAD_2; pfam06733
768486006416	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
768486006417	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
768486006418	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
768486006419	catalytic core [active]
768486006420	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
768486006421	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
768486006422	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
768486006423	Soluble P-type ATPase [General function prediction only]; Region: COG4087
768486006424	Protein of unknown function (DUF441); Region: DUF441; pfam04284
768486006425	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
768486006426	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
768486006427	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
768486006428	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
768486006429	Competence protein; Region: Competence; pfam03772
768486006430	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
768486006431	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
768486006432	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
768486006433	catalytic motif [active]
768486006434	Zn binding site [ion binding]; other site
768486006435	SLBB domain; Region: SLBB; pfam10531
768486006436	comEA protein; Region: comE; TIGR01259
768486006437	Helix-hairpin-helix motif; Region: HHH; pfam00633
768486006438	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
768486006439	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
768486006440	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
768486006441	protein binding site [polypeptide binding]; other site
768486006442	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
768486006443	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
768486006444	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
768486006445	active site
768486006446	(T/H)XGH motif; other site
768486006447	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
768486006448	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486006449	S-adenosylmethionine binding site [chemical binding]; other site
768486006450	Uncharacterized protein conserved in bacteria (DUF2129); Region: DUF2129; pfam09902
768486006451	Protein of unknown function (DUF964); Region: DUF964; pfam06133
768486006452	pyruvate carboxylase; Reviewed; Region: PRK12999
768486006453	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
768486006454	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
768486006455	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
768486006456	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
768486006457	active site
768486006458	catalytic residues [active]
768486006459	metal binding site [ion binding]; metal-binding site
768486006460	homodimer binding site [polypeptide binding]; other site
768486006461	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
768486006462	carboxyltransferase (CT) interaction site; other site
768486006463	biotinylation site [posttranslational modification]; other site
768486006464	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
768486006465	Protein of unknown function (DUF1507); Region: DUF1507; cl11487
768486006466	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
768486006467	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
768486006468	ATP binding site [chemical binding]; other site
768486006469	putative Mg++ binding site [ion binding]; other site
768486006470	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
768486006471	nucleotide binding region [chemical binding]; other site
768486006472	ATP-binding site [chemical binding]; other site
768486006473	RQC domain; Region: RQC; pfam09382
768486006474	HRDC domain; Region: HRDC; pfam00570
768486006475	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
768486006476	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
768486006477	G1 box; other site
768486006478	putative GEF interaction site [polypeptide binding]; other site
768486006479	GTP/Mg2+ binding site [chemical binding]; other site
768486006480	Switch I region; other site
768486006481	G2 box; other site
768486006482	G3 box; other site
768486006483	Switch II region; other site
768486006484	G4 box; other site
768486006485	G5 box; other site
768486006486	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
768486006487	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
768486006488	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
768486006489	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
768486006490	active site
768486006491	Uncharacterized protein family (UPF0223); Region: UPF0223; cl11484
768486006492	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
768486006493	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
768486006494	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
768486006495	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
768486006496	dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11855
768486006497	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
768486006498	E3 interaction surface; other site
768486006499	lipoyl attachment site [posttranslational modification]; other site
768486006500	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
768486006501	E3 interaction surface; other site
768486006502	lipoyl attachment site [posttranslational modification]; other site
768486006503	e3 binding domain; Region: E3_binding; pfam02817
768486006504	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
768486006505	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
768486006506	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
768486006507	alpha subunit interface [polypeptide binding]; other site
768486006508	TPP binding site [chemical binding]; other site
768486006509	heterodimer interface [polypeptide binding]; other site
768486006510	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
768486006511	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
768486006512	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
768486006513	tetramer interface [polypeptide binding]; other site
768486006514	TPP-binding site [chemical binding]; other site
768486006515	heterodimer interface [polypeptide binding]; other site
768486006516	phosphorylation loop region [posttranslational modification]
768486006517	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
768486006518	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
768486006519	DNA-binding site [nucleotide binding]; DNA binding site
768486006520	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
768486006521	pyridoxal 5'-phosphate binding site [chemical binding]; other site
768486006522	homodimer interface [polypeptide binding]; other site
768486006523	catalytic residue [active]
768486006524	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
768486006525	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
768486006526	active site
768486006527	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
768486006528	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
768486006529	active site
768486006530	catalytic tetrad [active]
768486006531	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
768486006532	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
768486006533	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
768486006534	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
768486006535	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
768486006536	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
768486006537	dimer interface [polypeptide binding]; other site
768486006538	putative catalytic residues [active]
768486006539	purine monophosphate binding site [chemical binding]; other site
768486006540	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
768486006541	MGS-like domain. This domain composes the whole protein of methylglyoxal synthetase, which catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The family also includes the C-terminal domain in carbamoyl phosphate...; Region: MGS-like; cl00245
768486006542	substrate binding site [chemical binding]; other site
768486006543	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
768486006544	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
768486006545	active site
768486006546	substrate binding site [chemical binding]; other site
768486006547	cosubstrate binding site; other site
768486006548	catalytic site [active]
768486006549	potential frameshift: common BLAST hit: gi|389868394|ref|YP_006375817.1| phosphoribosylformylglycinamidine cyclo-ligase
768486006550	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
768486006551	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
768486006552	dimerization interface [polypeptide binding]; other site
768486006553	putative ATP binding site [chemical binding]; other site
768486006554	Phosphoribosylaminoimidazole (AIR) synthetase [Nucleotide transport and metabolism]; Region: PurM; COG0150
768486006555	amidophosphoribosyltransferase; Provisional; Region: PRK07272
768486006556	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
768486006557	active site
768486006558	tetramer interface [polypeptide binding]; other site
768486006559	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
768486006560	active site
768486006561	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
768486006562	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
768486006563	dimerization interface [polypeptide binding]; other site
768486006564	ATP binding site [chemical binding]; other site
768486006565	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
768486006566	dimerization interface [polypeptide binding]; other site
768486006567	ATP binding site [chemical binding]; other site
768486006568	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
768486006569	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
768486006570	putative active site [active]
768486006571	catalytic triad [active]
768486006572	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; pfam02700
768486006573	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
768486006574	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
768486006575	ATP binding site [chemical binding]; other site
768486006576	active site
768486006577	substrate binding site [chemical binding]; other site
768486006578	adenylosuccinate lyase; Provisional; Region: PRK07492
768486006579	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
768486006580	tetramer interface [polypeptide binding]; other site
768486006581	active site
768486006582	potential frameshift: common BLAST hit: gi|332686826|ref|YP_004456600.1| phosphoribosylaminoimidazole carboxylase ATPase subunit
768486006583	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
768486006584	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
768486006585	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
768486006586	xanthine permease; Region: pbuX; TIGR03173
768486006587	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
768486006588	active site
768486006589	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
768486006590	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
768486006591	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
768486006592	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
768486006593	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
768486006594	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
768486006595	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
768486006596	Predicted membrane protein [Function unknown]; Region: COG4129
768486006597	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
768486006598	DUF939 C-terminal domain; Region: DUF939_C; pfam11728
768486006599	Predicted membrane protein [Function unknown]; Region: COG4129
768486006600	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
768486006601	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
768486006602	prohibitin homologues; Region: PHB; smart00244
768486006603	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
768486006604	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
768486006605	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486006606	motif II; other site
768486006607	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
768486006608	potential frameshift: common BLAST hit: gi|283787031|ref|YP_003366896.1| cation-transporting P-type ATPase
768486006609	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
768486006610	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
768486006611	DNA binding residues [nucleotide binding]
768486006612	dimer interface [polypeptide binding]; other site
768486006613	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
768486006614	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
768486006615	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
768486006616	intersubunit interface [polypeptide binding]; other site
768486006617	active site
768486006618	Zn2+ binding site [ion binding]; other site
768486006619	potential frameshift: common BLAST hit: gi|389868210|ref|YP_006375633.1| hexulose-6-phosphate isomerase
768486006620	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
768486006621	Metal-binding active site; metal-binding site
768486006622	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
768486006623	AP (apurinic/apyrimidinic) site pocket; other site
768486006624	DNA interaction; other site
768486006625	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
768486006626	active site
768486006627	dimer interface [polypeptide binding]; other site
768486006628	magnesium binding site [ion binding]; other site
768486006629	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
768486006630	active site
768486006631	P-loop; other site
768486006632	phosphorylation site [posttranslational modification]
768486006633	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
768486006634	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
768486006635	active site
768486006636	phosphorylation site [posttranslational modification]
768486006637	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
768486006638	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
768486006639	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
768486006640	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
768486006641	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
768486006642	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
768486006643	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
768486006644	active site
768486006645	dimer interface [polypeptide binding]; other site
768486006646	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
768486006647	non-specific DNA binding site [nucleotide binding]; other site
768486006648	salt bridge; other site
768486006649	sequence-specific DNA binding site [nucleotide binding]; other site
768486006650	aminotransferase AlaT; Validated; Region: PRK09265
768486006651	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
768486006652	pyridoxal 5'-phosphate binding site [chemical binding]; other site
768486006653	homodimer interface [polypeptide binding]; other site
768486006654	catalytic residue [active]
768486006655	Domain of unknown function (DUF378); Region: DUF378; pfam04070
768486006656	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
768486006657	Plasmid recombination enzyme; Region: Mob_Pre; pfam01076
768486006658	Gram positive anchor; Region: Gram_pos_anchor; pfam00746
768486006659	M protein trans-acting positive regulator (MGA) HTH domain; Region: HTH_Mga; pfam08280
768486006660	Mga helix-turn-helix domain; Region: Mga; pfam05043
768486006661	Mga helix-turn-helix domain; Region: Mga; pfam05043
768486006662	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
768486006663	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
768486006664	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
768486006665	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
768486006666	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
768486006667	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486006668	Walker A/P-loop; other site
768486006669	ATP binding site [chemical binding]; other site
768486006670	Q-loop/lid; other site
768486006671	ABC transporter signature motif; other site
768486006672	Walker B; other site
768486006673	D-loop; other site
768486006674	H-loop/switch region; other site
768486006675	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486006676	dimer interface [polypeptide binding]; other site
768486006677	conserved gate region; other site
768486006678	ABC-ATPase subunit interface; other site
768486006679	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
768486006680	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
768486006681	Uncharacterized conserved protein [Function unknown]; Region: COG1284
768486006682	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
768486006683	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
768486006684	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
768486006685	putative NAD(P) binding site [chemical binding]; other site
768486006686	dimer interface [polypeptide binding]; other site
768486006687	Transcriptional regulators [Transcription]; Region: PurR; COG1609
768486006688	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
768486006689	DNA binding site [nucleotide binding]
768486006690	domain linker motif; other site
768486006691	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
768486006692	ligand binding site [chemical binding]; other site
768486006693	dimerization interface [polypeptide binding]; other site
768486006694	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
768486006695	Domain of unknown function (DUF1803); Region: DUF1803; pfam08820
768486006696	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
768486006697	DHH family; Region: DHH; pfam01368
768486006698	DHHA2 domain; Region: DHHA2; pfam02833
768486006699	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
768486006700	beta-galactosidase; Region: BGL; TIGR03356
768486006701	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
768486006702	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
768486006703	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
768486006704	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
768486006705	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486006706	dimer interface [polypeptide binding]; other site
768486006707	conserved gate region; other site
768486006708	putative PBP binding loops; other site
768486006709	ABC-ATPase subunit interface; other site
768486006710	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
768486006711	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486006712	dimer interface [polypeptide binding]; other site
768486006713	conserved gate region; other site
768486006714	ABC-ATPase subunit interface; other site
768486006715	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
768486006716	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
768486006717	Protein of unknown function, DUF624; Region: DUF624; cl02369
768486006718	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
768486006719	Glycosyl hydrolase family 20 (GH20) catalytic domain of N-acetyl-beta-D-glucosaminidase (GcnA, also known as BhsA) and related proteins. GcnA  is an exoglucosidase which cleaves N-acetyl-beta-D-galactosamine (NAG) and N-acetyl-beta-D-galactosamine...; Region: GH20_GcnA-like; cd06565
768486006720	putative active site [active]
768486006721	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
768486006722	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
768486006723	potential frameshift: common BLAST hit: gi|251795515|ref|YP_003010246.1| AraC family transcriptional regulator
768486006724	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
768486006725	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
768486006726	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
768486006727	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
768486006728	FeS/SAM binding site; other site
768486006729	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
768486006730	Pyruvate formate lyase 1; Region: PFL1; cd01678
768486006731	coenzyme A binding site [chemical binding]; other site
768486006732	active site
768486006733	catalytic residues [active]
768486006734	glycine loop; other site
768486006735	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
768486006736	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
768486006737	CAP-like domain; other site
768486006738	active site
768486006739	primary dimer interface [polypeptide binding]; other site
768486006740	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
768486006741	potential frameshift: common BLAST hit: gi|29376174|ref|NP_815328.1| DNA topoisomerase IV subunit B
768486006742	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
768486006743	Glycerol-3-phosphate acyltransferase; Region: G3P_acyltransf; cl00410
768486006744	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
768486006745	active site
768486006746	catalytic residues [active]
768486006747	transcriptional repressor CodY; Validated; Region: PRK04158
768486006748	CodY GAF-like domain; Region: CodY; pfam06018
768486006749	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
768486006750	putative DNA binding site [nucleotide binding]; other site
768486006751	putative Zn2+ binding site [ion binding]; other site
768486006752	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
768486006753	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
768486006754	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486006755	Walker A motif; other site
768486006756	ATP binding site [chemical binding]; other site
768486006757	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
768486006758	Walker B motif; other site
768486006759	arginine finger; other site
768486006760	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
768486006761	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
768486006762	active site
768486006763	HslU subunit interaction site [polypeptide binding]; other site
768486006764	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
768486006765	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
768486006766	active site
768486006767	Int/Topo IB signature motif; other site
768486006768	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
768486006769	Glucose inhibited division protein A; Region: GIDA; pfam01134
768486006770	DNA topoisomerase I; Validated; Region: PRK05582
768486006771	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
768486006772	active site
768486006773	interdomain interaction site; other site
768486006774	putative metal-binding site [ion binding]; other site
768486006775	nucleotide binding site [chemical binding]; other site
768486006776	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
768486006777	domain I; other site
768486006778	DNA binding groove [nucleotide binding]
768486006779	phosphate binding site [ion binding]; other site
768486006780	domain II; other site
768486006781	domain III; other site
768486006782	nucleotide binding site [chemical binding]; other site
768486006783	catalytic site [active]
768486006784	domain IV; other site
768486006785	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
768486006786	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
768486006787	DNA protecting protein DprA; Region: dprA; TIGR00732
768486006788	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
768486006789	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
768486006790	RNA/DNA hybrid binding site [nucleotide binding]; other site
768486006791	active site
768486006792	ribosome biogenesis GTP-binding protein YlqF; Region: GTPase_YlqF; TIGR03596
768486006793	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
768486006794	GTP/Mg2+ binding site [chemical binding]; other site
768486006795	G4 box; other site
768486006796	G5 box; other site
768486006797	G1 box; other site
768486006798	Switch I region; other site
768486006799	G2 box; other site
768486006800	G3 box; other site
768486006801	Switch II region; other site
768486006802	LytTr DNA-binding domain; Region: LytTR; pfam04397
768486006803	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_24; cd09012
768486006804	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
768486006805	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
768486006806	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
768486006807	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
768486006808	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
768486006809	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cd06462
768486006810	Catalytic site [active]
768486006811	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
768486006812	hypothetical protein; Provisional; Region: PRK13672
768486006813	methionine sulfoxide reductase A; Provisional; Region: PRK14054
768486006814	Uncharacterized protein conserved in bacteria (DUF2140); Region: DUF2140; pfam09911
768486006815	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_YpmR_like; cd04506
768486006816	active site
768486006817	catalytic triad [active]
768486006818	oxyanion hole [active]
768486006819	EDD domain protein, DegV family; Region: DegV; TIGR00762
768486006820	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
768486006821	thymidylate synthase; Region: thym_sym; TIGR03284
768486006822	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
768486006823	dimerization interface [polypeptide binding]; other site
768486006824	active site
768486006825	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
768486006826	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
768486006827	folate binding site [chemical binding]; other site
768486006828	NADP+ binding site [chemical binding]; other site
768486006829	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
768486006830	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
768486006831	Walker A/P-loop; other site
768486006832	ATP binding site [chemical binding]; other site
768486006833	Q-loop/lid; other site
768486006834	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
768486006835	ABC transporter signature motif; other site
768486006836	Walker B; other site
768486006837	D-loop; other site
768486006838	ABC transporter; Region: ABC_tran_2; pfam12848
768486006839	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
768486006840	Putative cyclase; Region: Cyclase; pfam04199
768486006841	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
768486006842	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
768486006843	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
768486006844	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
768486006845	ADP_ribosylating enzymes catalyze the transfer of ADP_ribose from NAD+ to substrates. Bacterial toxins are cytoplasmic and catalyze the transfer of a single ADP_ribose unit to eukaryotic elongation factor 2, halting protein synthesis and killing the cell; Region: ADP_ribosyl; cl00283
768486006846	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
768486006847	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
768486006848	active site
768486006849	NTP binding site [chemical binding]; other site
768486006850	metal binding triad [ion binding]; metal-binding site
768486006851	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
768486006852	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
768486006853	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs; Region: NTP-PPase_BsYpjD; cd11531
768486006854	homodimer interface [polypeptide binding]; other site
768486006855	metal binding site [ion binding]; metal-binding site
768486006856	Uncharacterized conserved protein [Function unknown]; Region: COG1284
768486006857	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
768486006858	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
768486006859	UPF0302 domain; Region: UPF0302; pfam08864
768486006860	IDEAL domain; Region: IDEAL; pfam08858
768486006861	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
768486006862	TPR motif; other site
768486006863	binding surface
768486006864	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
768486006865	binding surface
768486006866	TPR motif; other site
768486006867	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
768486006868	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
768486006869	IHF dimer interface [polypeptide binding]; other site
768486006870	IHF - DNA interface [nucleotide binding]; other site
768486006871	GTP-binding protein Der; Reviewed; Region: PRK00093
768486006872	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
768486006873	G1 box; other site
768486006874	GTP/Mg2+ binding site [chemical binding]; other site
768486006875	Switch I region; other site
768486006876	G2 box; other site
768486006877	Switch II region; other site
768486006878	G3 box; other site
768486006879	G4 box; other site
768486006880	G5 box; other site
768486006881	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
768486006882	G1 box; other site
768486006883	GTP/Mg2+ binding site [chemical binding]; other site
768486006884	Switch I region; other site
768486006885	G2 box; other site
768486006886	G3 box; other site
768486006887	Switch II region; other site
768486006888	G4 box; other site
768486006889	G5 box; other site
768486006890	Transcriptional regulators [Transcription]; Region: PurR; COG1609
768486006891	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
768486006892	DNA binding site [nucleotide binding]
768486006893	domain linker motif; other site
768486006894	Ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs; Region: PBP1_Qymf_like; cd06291
768486006895	dimerization interface [polypeptide binding]; other site
768486006896	ligand binding site [chemical binding]; other site
768486006897	sodium binding site [ion binding]; other site
768486006898	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
768486006899	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
768486006900	substrate binding [chemical binding]; other site
768486006901	active site
768486006902	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
768486006903	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
768486006904	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
768486006905	active site turn [active]
768486006906	phosphorylation site [posttranslational modification]
768486006907	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
768486006908	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
768486006909	HPr interaction site; other site
768486006910	glycerol kinase (GK) interaction site [polypeptide binding]; other site
768486006911	active site
768486006912	phosphorylation site [posttranslational modification]
768486006913	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
768486006914	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
768486006915	nucleotide binding site [chemical binding]; other site
768486006916	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
768486006917	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
768486006918	RNA binding site [nucleotide binding]; other site
768486006919	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
768486006920	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
768486006921	RNA binding site [nucleotide binding]; other site
768486006922	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
768486006923	RNA binding site [nucleotide binding]; other site
768486006924	cytidylate kinase; Provisional; Region: cmk; PRK00023
768486006925	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
768486006926	CMP-binding site; other site
768486006927	The sites determining sugar specificity; other site
768486006928	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
768486006929	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
768486006930	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
768486006931	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
768486006932	ATP binding site [chemical binding]; other site
768486006933	putative Mg++ binding site [ion binding]; other site
768486006934	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
768486006935	nucleotide binding region [chemical binding]; other site
768486006936	ATP-binding site [chemical binding]; other site
768486006937	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4955
768486006938	Protein of unknown function (DUF1271); Region: DUF1271; cl01443
768486006939	4Fe-4S single cluster domain; Region: Fer4_13; pfam13370
768486006940	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
768486006941	hypothetical protein; Provisional; Region: PRK07205
768486006942	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
768486006943	active site
768486006944	metal binding site [ion binding]; metal-binding site
768486006945	Predicted membrane protein [Function unknown]; Region: COG1288
768486006946	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
768486006947	Predicted membrane protein [Function unknown]; Region: COG3601
768486006948	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
768486006949	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
768486006950	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
768486006951	RNA binding surface [nucleotide binding]; other site
768486006952	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
768486006953	active site
768486006954	Putative transcriptional regulators (Ypuh-like); Region: DUF387; cl00612
768486006955	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
768486006956	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
768486006957	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
768486006958	active site
768486006959	Int/Topo IB signature motif; other site
768486006960	ferric uptake regulator; Provisional; Region: fur; PRK09462
768486006961	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
768486006962	metal binding site 2 [ion binding]; metal-binding site
768486006963	putative DNA binding helix; other site
768486006964	metal binding site 1 [ion binding]; metal-binding site
768486006965	dimer interface [polypeptide binding]; other site
768486006966	structural Zn2+ binding site [ion binding]; other site
768486006967	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
768486006968	S1 domain; Region: S1_2; pfam13509
768486006969	TFIIB zinc-binding; Region: TF_Zn_Ribbon; pfam08271
768486006970	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
768486006971	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
768486006972	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
768486006973	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
768486006974	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
768486006975	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
768486006976	DNA binding residues [nucleotide binding]
768486006977	DNA primase; Validated; Region: dnaG; PRK05667
768486006978	CHC2 zinc finger; Region: zf-CHC2; pfam01807
768486006979	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
768486006980	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
768486006981	active site
768486006982	metal binding site [ion binding]; metal-binding site
768486006983	interdomain interaction site; other site
768486006984	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
768486006985	ATPase, P-type (transporting), HAD superfamily, subfamily IC; Region: ATPase_P-type; TIGR01494
768486006986	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
768486006987	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486006988	motif II; other site
768486006989	Domain of unknown function (DUF368); Region: DUF368; cl00893
768486006990	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
768486006991	N-acetyl-D-glucosamine binding site [chemical binding]; other site
768486006992	catalytic residue [active]
768486006993	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
768486006994	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
768486006995	Serine hydrolase (FSH1); Region: FSH1; pfam03959
768486006996	Predicted integral membrane protein [Function unknown]; Region: COG0392
768486006997	Uncharacterized conserved protein [Function unknown]; Region: COG2898
768486006998	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
768486006999	elongation factor Tu; Reviewed; Region: PRK00049
768486007000	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
768486007001	G1 box; other site
768486007002	GEF interaction site [polypeptide binding]; other site
768486007003	GTP/Mg2+ binding site [chemical binding]; other site
768486007004	Switch I region; other site
768486007005	G2 box; other site
768486007006	G3 box; other site
768486007007	Switch II region; other site
768486007008	G4 box; other site
768486007009	G5 box; other site
768486007010	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
768486007011	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
768486007012	Antibiotic Binding Site [chemical binding]; other site
768486007013	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
768486007014	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486007015	Coenzyme A binding pocket [chemical binding]; other site
768486007016	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
768486007017	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_3; cd07241
768486007018	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
768486007019	putative metal binding site [ion binding]; other site
768486007020	37-kD nucleoid-associated bacterial protein; Region: NA37; cl15473
768486007021	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
768486007022	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
768486007023	active site
768486007024	catalytic tetrad [active]
768486007025	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
768486007026	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
768486007027	active site
768486007028	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
768486007029	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
768486007030	homodimer interface [polypeptide binding]; other site
768486007031	catalytic residues [active]
768486007032	NAD binding site [chemical binding]; other site
768486007033	substrate binding pocket [chemical binding]; other site
768486007034	flexible flap; other site
768486007035	putative acyltransferase; Provisional; Region: PRK05790
768486007036	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
768486007037	dimer interface [polypeptide binding]; other site
768486007038	active site
768486007039	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
768486007040	3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade; Region: HMG-CoA-S_prok; TIGR01835
768486007041	dimer interface [polypeptide binding]; other site
768486007042	active site
768486007043	Viral enhancin protein; Region: Enhancin; pfam03272
768486007044	Peptidase M60-like family; Region: M60-like; pfam13402
768486007045	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486007046	S-adenosylmethionine binding site [chemical binding]; other site
768486007047	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
768486007048	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
768486007049	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
768486007050	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
768486007051	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486007052	motif II; other site
768486007053	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
768486007054	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
768486007055	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
768486007056	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
768486007057	putative active site [active]
768486007058	catalytic site [active]
768486007059	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
768486007060	putative active site [active]
768486007061	catalytic site [active]
768486007062	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
768486007063	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
768486007064	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
768486007065	WxL domain surface cell wall-binding; Region: WxL; pfam13731
768486007066	WxL domain surface cell wall-binding; Region: WxL; pfam13731
768486007067	LPXTG-motif cell wall anchor domain; Region: LPXTG_anchor; TIGR01167
768486007068	Class I aldolases; Region: Aldolase_Class_I; cl17187
768486007069	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
768486007070	active site
768486007071	phosphorylation site [posttranslational modification]
768486007072	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
768486007073	active site
768486007074	P-loop; other site
768486007075	phosphorylation site [posttranslational modification]
768486007076	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
768486007077	potential frameshift: common BLAST hit: gi|29375290|ref|NP_814443.1| 1-phosphofructokinase
768486007078	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
768486007079	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
768486007080	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
768486007081	putative active site [active]
768486007082	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
768486007083	dimer interface [polypeptide binding]; other site
768486007084	substrate binding site [chemical binding]; other site
768486007085	ATP binding site [chemical binding]; other site
768486007086	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
768486007087	Ligand Binding Site [chemical binding]; other site
768486007088	potential frameshift: common BLAST hit: gi|317131824|ref|YP_004091138.1| 6-phospho-beta-glucosidase
768486007089	potential frameshift: common BLAST hit: gi|383328570|ref|YP_005354454.1| PTS system lactose/cellobiose-specific transporter subunit IIC
768486007090	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
768486007091	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
768486007092	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
768486007093	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
768486007094	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
768486007095	DNA-binding site [nucleotide binding]; DNA binding site
768486007096	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
768486007097	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
768486007098	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
768486007099	Zn binding site [ion binding]; other site
768486007100	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
768486007101	Zn binding site [ion binding]; other site
768486007102	Predicted esterase [General function prediction only]; Region: COG0400
768486007103	WxL domain surface cell wall-binding; Region: WxL; pfam13731
768486007104	Bacterial protein of unknown function (DUF916); Region: DUF916; pfam06030
768486007105	Protein of unknown function C-terminal (DUF3324); Region: DUF3324; pfam11797
768486007106	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; pfam03829
768486007107	Predicted homoserine dehydrogenase [Amino acid transport and metabolism]; Region: COG4091
768486007108	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
768486007109	SAF domain of putative dehydrogenases or oxidoreductases; Region: SAF_DH_OX_like; cd11616
768486007110	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_10; cd12171
768486007111	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
768486007112	putative ligand binding site [chemical binding]; other site
768486007113	putative NAD binding site [chemical binding]; other site
768486007114	catalytic site [active]
768486007115	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
768486007116	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
768486007117	NAD(P) binding site [chemical binding]; other site
768486007118	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
768486007119	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
768486007120	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
768486007121	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; cl01515
768486007122	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
768486007123	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
768486007124	DNA binding residues [nucleotide binding]
768486007125	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
768486007126	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
768486007127	dimer interface [polypeptide binding]; other site
768486007128	substrate binding site [chemical binding]; other site
768486007129	ATP binding site [chemical binding]; other site
768486007130	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
768486007131	substrate binding site [chemical binding]; other site
768486007132	multimerization interface [polypeptide binding]; other site
768486007133	ATP binding site [chemical binding]; other site
768486007134	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
768486007135	thiamine phosphate binding site [chemical binding]; other site
768486007136	active site
768486007137	pyrophosphate binding site [ion binding]; other site
768486007138	Putative transcription activator [Transcription]; Region: TenA; COG0819
768486007139	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
768486007140	Zn2+ binding site [ion binding]; other site
768486007141	Mg2+ binding site [ion binding]; other site
768486007142	potential protein location (hypothetical protein EHR_13975 [Enterococcus hirae ATCC 9790]) that overlaps RNA (tRNA-H)
768486007143	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
768486007144	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
768486007145	dimerization interface [polypeptide binding]; other site
768486007146	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
768486007147	dimer interface [polypeptide binding]; other site
768486007148	phosphorylation site [posttranslational modification]
768486007149	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
768486007150	ATP binding site [chemical binding]; other site
768486007151	Mg2+ binding site [ion binding]; other site
768486007152	G-X-G motif; other site
768486007153	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
768486007154	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
768486007155	active site
768486007156	phosphorylation site [posttranslational modification]
768486007157	intermolecular recognition site; other site
768486007158	dimerization interface [polypeptide binding]; other site
768486007159	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
768486007160	DNA binding site [nucleotide binding]
768486007161	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
768486007162	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
768486007163	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
768486007164	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
768486007165	Predicted metal-binding, possibly nucleic acid-binding protein [General function prediction only]; Region: COG1399
768486007166	Transcriptional regulator [Transcription]; Region: LysR; COG0583
768486007167	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
768486007168	The substrate binding domain of LysR-type transcriptional regulator MleR which required for malolactic fermentation, contains type 2 periplasmic binidning fold; Region: PBP2_MleR; cd08437
768486007169	putative dimerization interface [polypeptide binding]; other site
768486007170	pyruvate kinase; Provisional; Region: PRK06354
768486007171	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
768486007172	active site
768486007173	domain interfaces; other site
768486007174	Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848
768486007175	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
768486007176	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
768486007177	active site
768486007178	ADP/pyrophosphate binding site [chemical binding]; other site
768486007179	dimerization interface [polypeptide binding]; other site
768486007180	allosteric effector site; other site
768486007181	fructose-1,6-bisphosphate binding site; other site
768486007182	potential frameshift: common BLAST hit: gi|29375623|ref|NP_814777.1| DNA polymerase III, alpha subunit
768486007183	Protein of unknown function (DUF2929); Region: DUF2929; pfam11151
768486007184	drug efflux system protein MdtG; Provisional; Region: PRK09874
768486007185	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486007186	putative substrate translocation pore; other site
768486007187	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
768486007188	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
768486007189	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486007190	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
768486007191	active site
768486007192	motif I; other site
768486007193	motif II; other site
768486007194	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
768486007195	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
768486007196	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
768486007197	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
768486007198	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
768486007199	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
768486007200	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
768486007201	putative active site [active]
768486007202	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
768486007203	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
768486007204	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
768486007205	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
768486007206	active site
768486007207	dimer interface [polypeptide binding]; other site
768486007208	motif 1; other site
768486007209	motif 2; other site
768486007210	motif 3; other site
768486007211	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
768486007212	anticodon binding site; other site
768486007213	4-oxalocrotonate tautomerase; Provisional; Region: PRK02220
768486007214	active site 1 [active]
768486007215	dimer interface [polypeptide binding]; other site
768486007216	hexamer interface [polypeptide binding]; other site
768486007217	active site 2 [active]
768486007218	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
768486007219	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
768486007220	Soluble P-type ATPase [General function prediction only]; Region: COG4087
768486007221	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
768486007222	Part of AAA domain; Region: AAA_19; pfam13245
768486007223	Family description; Region: UvrD_C_2; pfam13538
768486007224	hypothetical protein; Provisional; Region: PRK12378
768486007225	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
768486007226	hypothetical protein; Provisional; Region: PRK13670
768486007227	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486007228	S-adenosylmethionine binding site [chemical binding]; other site
768486007229	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
768486007230	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
768486007231	Zn2+ binding site [ion binding]; other site
768486007232	Mg2+ binding site [ion binding]; other site
768486007233	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
768486007234	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
768486007235	active site
768486007236	(T/H)XGH motif; other site
768486007237	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
768486007238	GTPase YqeH; Provisional; Region: PRK13796
768486007239	Circularly permuted YqeH GTPase; Region: YqeH; cd01855
768486007240	GTP/Mg2+ binding site [chemical binding]; other site
768486007241	G4 box; other site
768486007242	G5 box; other site
768486007243	G1 box; other site
768486007244	Switch I region; other site
768486007245	G2 box; other site
768486007246	G3 box; other site
768486007247	Switch II region; other site
768486007248	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
768486007249	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
768486007250	active site
768486007251	motif I; other site
768486007252	motif II; other site
768486007253	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
768486007254	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
768486007255	Walker A/P-loop; other site
768486007256	ATP binding site [chemical binding]; other site
768486007257	Q-loop/lid; other site
768486007258	ABC transporter signature motif; other site
768486007259	Walker B; other site
768486007260	D-loop; other site
768486007261	H-loop/switch region; other site
768486007262	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
768486007263	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
768486007264	dimer interface [polypeptide binding]; other site
768486007265	conserved gate region; other site
768486007266	putative PBP binding loops; other site
768486007267	ABC-ATPase subunit interface; other site
768486007268	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
768486007269	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
768486007270	substrate binding pocket [chemical binding]; other site
768486007271	membrane-bound complex binding site; other site
768486007272	hinge residues; other site
768486007273	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486007274	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
768486007275	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486007276	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486007277	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486007278	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486007279	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
768486007280	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
768486007281	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
768486007282	potential frameshift: common BLAST hit: gi|29377343|ref|NP_816497.1| acetyl-CoA carboxylase biotin carboxylase subunit
768486007283	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
768486007284	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
768486007285	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
768486007286	carboxyltransferase (CT) interaction site; other site
768486007287	biotinylation site [posttranslational modification]; other site
768486007288	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
768486007289	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
768486007290	dimer interface [polypeptide binding]; other site
768486007291	active site
768486007292	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
768486007293	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
768486007294	NAD(P) binding site [chemical binding]; other site
768486007295	homotetramer interface [polypeptide binding]; other site
768486007296	homodimer interface [polypeptide binding]; other site
768486007297	active site
768486007298	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
768486007299	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
768486007300	acyl carrier protein; Provisional; Region: acpP; PRK00982
768486007301	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
768486007302	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
768486007303	dimer interface [polypeptide binding]; other site
768486007304	active site
768486007305	CoA binding pocket [chemical binding]; other site
768486007306	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
768486007307	MarR family; Region: MarR_2; pfam12802
768486007308	Nuclease subunit of the excinuclease complex [DNA replication, recombination, and repair]; Region: UvrC; COG0322
768486007309	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
768486007310	GIY-YIG motif/motif A; other site
768486007311	active site
768486007312	catalytic site [active]
768486007313	putative DNA binding site [nucleotide binding]; other site
768486007314	metal binding site [ion binding]; metal-binding site
768486007315	Protein of unknown function (DUF1797); Region: DUF1797; pfam08796
768486007316	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
768486007317	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
768486007318	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
768486007319	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
768486007320	putative ADP-binding pocket [chemical binding]; other site
768486007321	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
768486007322	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
768486007323	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
768486007324	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
768486007325	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
768486007326	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
768486007327	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
768486007328	dimerization domain swap beta strand [polypeptide binding]; other site
768486007329	regulatory protein interface [polypeptide binding]; other site
768486007330	active site
768486007331	regulatory phosphorylation site [posttranslational modification]; other site
768486007332	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486007333	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
768486007334	Walker A motif; other site
768486007335	ATP binding site [chemical binding]; other site
768486007336	Walker B motif; other site
768486007337	arginine finger; other site
768486007338	UvrB/uvrC motif; Region: UVR; pfam02151
768486007339	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
768486007340	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
768486007341	Walker A motif; other site
768486007342	ATP binding site [chemical binding]; other site
768486007343	Walker B motif; other site
768486007344	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
768486007345	Domain of unknown function (DUF1827); Region: DUF1827; pfam08860
768486007346	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
768486007347	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
768486007348	active site
768486007349	homodimer interface [polypeptide binding]; other site
768486007350	potential frameshift: common BLAST hit: gi|29375298|ref|NP_814452.1| peptide chain release factor 3
768486007351	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
768486007352	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
768486007353	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
768486007354	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cd01083
768486007355	substrate binding site [chemical binding]; other site
768486007356	catalytic residues [active]
768486007357	CAMP factor (Cfa); Region: CAMP_factor; pfam07373
768486007358	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
768486007359	Domain of unknown function DUF21; Region: DUF21; pfam01595
768486007360	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
768486007361	Transporter associated domain; Region: CorC_HlyC; pfam03471
768486007362	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
768486007363	Domain of unknown function DUF20; Region: UPF0118; pfam01594
768486007364	Autoinducer synthetase; Region: Autoind_synth; cl17404
768486007365	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
768486007366	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
768486007367	Coenzyme A binding pocket [chemical binding]; other site
768486007368	hypothetical protein; Provisional; Region: PRK13662
768486007369	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
768486007370	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
768486007371	minor groove reading motif; other site
768486007372	helix-hairpin-helix signature motif; other site
768486007373	substrate binding pocket [chemical binding]; other site
768486007374	active site
768486007375	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
768486007376	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
768486007377	DNA binding and oxoG recognition site [nucleotide binding]
768486007378	RecX family; Region: RecX; cl00936
768486007379	TRAM domain; Region: TRAM; pfam01938
768486007380	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
768486007381	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
768486007382	S-adenosylmethionine binding site [chemical binding]; other site
768486007383	Uncharacterized protein/domain associated with GTPases [Function unknown]; Region: COG3597
768486007384	Chitin binding domain; Region: Chitin_bind_3; pfam03067
768486007385	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
768486007386	active site
768486007387	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
768486007388	Interdomain contacts; other site
768486007389	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
768486007390	Cytokine receptor motif; other site
768486007391	chitin-binding domain of Chi A1-like proteins; Region: ChiA1_BD; cd12214
768486007392	TspO/MBR family; Region: TspO_MBR; pfam03073
768486007393	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
768486007394	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
768486007395	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245