-- dump date 20140619_061412 -- class Genbank::CDS -- table cds_note -- id note YP_004369081.1 COGs: COG0593 ATPase involved in DNA replication initiation; HAMAP: Chromosomal replication control, initiator DnaA; InterPro IPR001957:IPR013159:IPR013317; KEGG: dat:HRM2_18560 DnaA; PFAM: Chromosomal replication control, initiator (DnaA)/regulator (Hda); Chromosomal replication initiator, DnaA C-terminal; SMART: Chromosomal replication initiator, DnaA C-terminal; SPTR: Chromosomal replication initiator protein dnaA; TIGRFAM: Chromosomal replication control, initiator DnaA; PFAM: domain; Bacterial dnaA protein; TIGRFAM: chromosomal replication initiator protein DnaA YP_004369082.1 COGs: COG2820 Uridine phosphorylase; InterPro IPR000845; KEGG: vdi:Vdis_1659 uridine phosphorylase; PFAM: nucleoside phosphorylase domain; SPTR: Uridine phosphorylase; PFAM: phosphorylase superfamily YP_004369083.1 COGs: COG1893 Ketopantoate reductase; InterPro IPR003710:IPR013332:IPR013752; KEGG: aco:Amico_0087 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, C-terminal; Ketopantoate reductase ApbA/PanE, N-terminal; PRIAM: 2-dehydropantoate 2-reductase; SPTR: 2-dehydropantoate 2-reductase; TIGRFAM: Ketopantoate reductase ApbA/PanE; PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase YP_004369084.1 KEGG: sfu:Sfum_1363 hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacterial protein of unknown function (Gcw_chp); TIGRFAM: conserved hypothetical protein, proteobacterial YP_004369085.1 COGs: COG0347 nitrogen regulatory protein PII; InterPro IPR002187; KEGG: gbe:GbCGDNIH1_0959 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein PII; SMART: nitrogen regulatory protein PII; SPTR: nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II YP_004369086.1 COGs: COG0004 Ammonia permease; InterPro IPR001905; KEGG: sfu:Sfum_0727 ammonium transporter; PFAM: Ammonium transporter; SPTR: Ammonium transporter; TIGRFAM: Ammonium transporter; PFAM: Ammonium transporter Family; TIGRFAM: ammonium transporter YP_004369087.1 COGs: COG0125 Thymidylate kinase; HAMAP: Thymidylate kinase; InterPro IPR018094; KEGG: dak:DaAHT2_1164 thymidylate kinase; PFAM: Thymidylate kinase; PRIAM: dTMP kinase; SPTR: Thymidylate kinase; TIGRFAM: Thymidylate kinase; PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase YP_004369088.1 COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: glo:Glov_2790 heat shock protein HSP20; PFAM: Heat shock protein Hsp20; SPTR: HspC2 heat shock protein; PFAM: Hsp20/alpha crystallin family YP_004369089.1 COGs: COG0540 aspartate carbamoyltransferase catalytic chain; HAMAP: aspartate carbamoyltransferase, eukaryotic; InterPro IPR002082:IPR006132:IPR006131; KEGG: sat:SYN_01532 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; PRIAM: aspartate carbamoyltransferase; SPTR: aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase, eukaryotic; PFAM: aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase YP_004369090.1 COGs: COG0044 dihydroorotase and related cyclic amidohydrolase; InterPro IPR004722:IPR006680; KEGG: gur:Gura_1857 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; SPTR: dihydroorotase; TIGRFAM: dihydroorotase; PFAM: Amidohydrolase; TIGRFAM: dihydroorotase, multifunctional complex type YP_004369091.1 KEGG: msi:Msm_1646 ATPase; SPTR: uncharacterized protein YP_004369092.1 COGs: COG2768 Uncharacterized Fe-S center protein; InterPro IPR001450; KEGG: dol:Dole_2297 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_004369093.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR006638:IPR007197; KEGG: sfu:Sfum_3056 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: radical SAM protein; PFAM: Radical SAM superfamily; TIGRFAM: heme d1 biosynthesis radical SAM protein NirJ1; radical SAM additional 4Fe4S-binding domain YP_004369094.1 COGs: COG1219 ATP-dependent protease Clp ATPase subunit; InterPro IPR003593:IPR013093; KEGG: sfu:Sfum_3055 ATPase; PFAM: ATPase, AAA-2; SMART: ATPase, AAA+ type, core; SPTR: ATPase AAA; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX) YP_004369095.1 COGs: COG2262 GTPase; InterPro IPR016496:IPR005225:IPR002917; KEGG: sat:SYN_01762 GTPase; PFAM: GTP-binding protein, HSR1-related; SPTR: GTPase; TIGRFAM: GTP-binding protein, HflX; Small GTP-binding protein; manually curated; PFAM: GTPase of unknown function; TIGRFAM: GTP-binding protein HflX; small GTP-binding protein domain YP_004369096.1 COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR004410:IPR020801:IPR014043; KEGG: dbr:Deba_1955 malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase; PRIAM: [acyl-carrier-protein] S-malonyltransferase; SMART: polyketide synthase, acyl transferase domain; SPTR: Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase YP_004369097.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: tko:TK0704 SAM-dependent methyltransferase; PFAM: methyltransferase type 11; SPTR: uncharacterized protein; PFAM: methyltransferase domain YP_004369098.1 COGs: COG0606 ATPase with chaperone activity; InterPro IPR004482:IPR003593:IPR000523; KEGG: gur:Gura_4031 Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, ChlI subunit; SMART: ATPase, AAA+ type, core; SPTR: Mg chelatase-like protein; TIGRFAM: Mg chelatase-related protein; PFAM: Magnesium chelatase, subunit ChlI; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: Mg chelatase-related protein YP_004369099.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: sfu:Sfum_2764 two component, sigma54 specific, fis family transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain YP_004369100.1 COGs: COG4123 O-methyltransferase; InterPro IPR013216; KEGG: sat:SYN_01006 methyltransferase; PFAM: methyltransferase type 11; SPTR: methyltransferase; manually curated; PFAM: methyltransferase small domain YP_004369101.1 COGs: COG4198 conserved hypothetical protein; InterPro IPR008323; KEGG: dbr:Deba_0226 hypothetical protein; PFAM: Uncharacterised conserved protein UCP033563; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1015) YP_004369102.1 COGs: COG0079 histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; HAMAP: histidinol-phosphate aminotransferase; InterPro IPR005861:IPR004839; KEGG: sfu:Sfum_2116 histidinol-phosphate aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: histidinol-phosphate transaminase; SPTR: histidinol-phosphate aminotransferase 2; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase YP_004369103.1 COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136:IPR011994; KEGG: cya:CYA_2663 bifunctional pantoate ligase/cytidylate kinase; PFAM: Cytidylate kinase domain; SPTR: bifunctional pantoate ligase/cytidylate kinase; TIGRFAM: Cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase YP_004369104.1 COGs: COG0539 ribosomal protein S1; InterPro IPR018032:IPR022967:IPR003029; KEGG: sfu:Sfum_2118 ribosomal protein S1; PFAM: ribosomal protein S1, RNA-binding domain; SMART: RNA-binding domain, S1; SPTR: SSU ribosomal protein S1P; TIGRFAM: ribosomal S1 synthesis/modification protein; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1 YP_004369105.1 COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR004635:IPR002142; KEGG: sfu:Sfum_2119 signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; SPTR: protease slr0021; TIGRFAM: peptidase S49, SppA; PFAM: peptidase S49; TIGRFAM: signal peptide peptidase SppA, 36K type YP_004369106.1 COGs: COG0009 translation factor (SUA5); InterPro IPR004388:IPR006070; KEGG: dat:HRM2_24790 hypothetical protein; PFAM: Sua5/YciO/YrdC, N-terminal; SPTR: Uncharacterized protein yciO; TIGRFAM: Sua5/YciO/YrdC/YwlC; manually curated; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein YP_004369107.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: dak:DaAHT2_1339 peptidase M23; PFAM: peptidase M23; SPTR: peptidase M23B; PFAM: peptidase M23 YP_004369108.1 COGs: COG0812 UDP-N-acetylmuramate dehydrogenase; HAMAP: UDP-N-acetylenolpyruvoylglucosamine reductase; InterPro IPR003170:IPR006094:IPR011601; KEGG: cya:CYA_1875 UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: UDP-N-acetylmuramate dehydrogenase; SPTR: UDP-N-acetylenolpyruvoylglucosamine reductase; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: FAD binding domain; UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase YP_004369109.1 COGs: COG2231 Uncharacterized protein related to Endonuclease III; InterPro IPR003265; KEGG: gsu:GSU3377 helix-hairpin-helix domain-containing protein; PFAM: HhH-GPD domain; SMART: HhH-GPD domain; SPTR: HhH-GPD family protein; PFAM: HhH-GPD superfamily base excision DNA repair protein YP_004369110.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: sfu:Sfum_1755 ABC transporter related; PFAM: ABC transporter-like; PRIAM: sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter YP_004369111.1 InterPro IPR013525; KEGG: sfu:Sfum_1754 ABC-type transport system involved in multi-copper enzyme maturation, permease component; PFAM: ABC transporter; SPTR: ABC-type transport system involved in multi-copper enzyme maturation, permease component; PFAM: ABC transporter YP_004369112.1 COGs: COG3225 ABC transporter involved in gliding motility auxiliary component; InterPro IPR019196; KEGG: sfu:Sfum_1753 ABC transporter involved in gliding motility auxiliary component-like; PFAM: ABC-type uncharacterised transport system; SPTR: ABC transporter involved in gliding motility auxiliary component-like; PFAM: ABC transporter YP_004369113.1 KEGG: sfu:Sfum_1752 hypothetical protein; SPTR: uncharacterized protein YP_004369114.1 COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: sfu:Sfum_3130 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase YP_004369115.1 KEGG: sfu:Sfum_3131 hypothetical protein; SPTR: uncharacterized protein; PFAM: methylene-tetrahydrofolate reductase C terminal YP_004369116.1 COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: mta:Moth_1193 methyl-viologen-reducing hydrogenase, delta subunit; PFAM: methyl-viologen-reducing hydrogenase, delta subunit; SPTR: F420-non-reducing hydrogenase vhu iron-sulfur subunit D; PFAM: methyl-viologen-reducing hydrogenase, delta subunit YP_004369117.1 COGs: COG0039 Malate/lactate dehydrogenase; HAMAP: Malate dehydrogenase, NAD-dependent; InterPro IPR011275:IPR001236:IPR022383; KEGG: rrs:RoseRS_0253 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, C-terminal; Lactate/malate dehydrogenase, N-terminal; SPTR: Malate dehydrogenase; TIGRFAM: Malate dehydrogenase, NAD-dependent; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: malate dehydrogenase, NAD-dependent YP_004369118.1 COGs: COG0730 permease; InterPro IPR002781; KEGG: dat:HRM2_34990 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004369119.1 KEGG: mta:Moth_2215 hypothetical protein; SPTR: uncharacterized protein YP_004369120.1 COGs: COG1912 conserved hypothetical protein; InterPro IPR002747; KEGG: dal:Dalk_3152 protein of unknown function DUF62; PFAM: protein of unknown function DUF62; SPTR: uncharacterized protein; PFAM: S-adenosyl-l-methionine hydroxide adenosyltransferase YP_004369121.1 COGs: COG3387 glucoamylase and related glycosyl hydrolase; InterPro IPR011613; KEGG: tro:trd_1824 glycosyl hydrolase, family 15; PFAM: glycoside hydrolase 15-related; SPTR: Similar to glucan 1,4-alpha-glucosidase (glucoamylase); PFAM: glycosyl hydrolases family 15 YP_004369122.1 COGs: COG1525 Micrococcal nuclease (thermonuclease) homologs; InterPro IPR006021; KEGG: dal:Dalk_0740 nuclease (SNase domain protein); PFAM: Staphylococcal nuclease (SNase-like); SMART: Staphylococcal nuclease (SNase-like); SPTR: Nuclease (SNase domain protein); PFAM: Staphylococcal nuclease homologue YP_004369123.1 COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: gur:Gura_2307 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-glucuronate decarboxylase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase YP_004369124.1 InterPro IPR001387; KEGG: dac:Daci_1755 XRE family transcriptional regulator; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: XRE family transcriptional regulator; PFAM: Helix-turn-helix YP_004369125.1 COGs: COG4584 transposase and inactivated derivatives; InterPro IPR001584; KEGG: mta:Moth_2239 integrase catalytic subunit; PFAM: Integrase, catalytic core; SPTR: Integrase, catalytic region; PFAM: Integrase core domain YP_004369126.1 COGs: COG1484 DNA replication protein; InterPro IPR003593:IPR002611; KEGG: mta:Moth_2240 IstB-like ATP-binding protein; PFAM: IstB-like ATP-binding protein; SMART: ATPase, AAA+ type, core; SPTR: IstB-like ATP-binding protein; PFAM: IstB-like ATP binding protein YP_004369127.1 KEGG: ptr:737059 hypothetical protein LOC737059; SPTR: MST148 protein YP_004369128.1 KEGG: cyt:cce_4320 hypothetical protein; SPTR: uncharacterized protein YP_004369129.1 KEGG: pfr:PFREUD_21230 hypothetical protein; SPTR: uncharacterized protein YP_004369130.1 COGs: COG1961 Site-specific recombinase DNA invertase Pin homologs; InterPro IPR006119; KEGG: glo:Glov_2327 resolvase domain; PFAM: Resolvase, N-terminal; SMART: Resolvase, N-terminal; SPTR: resolvase; PFAM: Resolvase, N terminal domain YP_004369131.1 KEGG: pth:PTH_2492 hypothetical protein; SPTR: uncharacterized protein YP_004369132.1 InterPro IPR006339:IPR007159; KEGG: dau:Daud_0407 AbrB family transcriptional regulator; PFAM: transcription regulator AbrB/SpoV, predicted; SMART: transcription regulator AbrB/SpoV, predicted; SPTR: AbrB family transcriptional regulator; TIGRFAM: transcription regulator AbrB; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family YP_004369133.1 InterPro IPR002716; KEGG: dau:Daud_0408 twitching mobility protein PilT; PFAM: PilT protein, N-terminal; SPTR: twitching mobility protein PilT; PFAM: PIN domain YP_004369134.1 KEGG: mta:Moth_0412 2-oxoisovalerate dehydrogenase, E1 component beta subunit; SPTR: 2-oxoisovalerate dehydrogenase, E1 component beta subunit YP_004369135.1 InterPro IPR006339:IPR007159; KEGG: sfu:Sfum_0409 AbrB family transcriptional regulator; SMART: transcription regulator AbrB/SpoV, predicted; SPTR: AbrB family transcriptional regulator; TIGRFAM: transcription regulator AbrB; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family YP_004369136.1 COGs: COG1569 nucleic acid-binding protein contains PIN domain; InterPro IPR002850; KEGG: gur:Gura_1139 nucleotide binding protein, PINc; SPTR: nucleotide binding protein, PINc; TIGRFAM: protein of unknown function DUF132; TIGRFAM: toxin-antitoxin system toxin component, PIN family YP_004369137.1 COGs: COG1569 nucleic acid-binding protein contains PIN domain; InterPro IPR002850:IPR006596; KEGG: sus:Acid_0896 nucleic acid binding protein; SMART: nucleotide binding protein, PINc; SPTR: Nucleic acid-binding protein contains PIN domain-like protein; TIGRFAM: protein of unknown function DUF132; TIGRFAM: toxin-antitoxin system toxin component, PIN family YP_004369138.1 InterPro IPR006442; KEGG: sus:Acid_0897 prevent-host-death family protein; SPTR: Prevent-host-death family protein; TIGRFAM: Prevent-host-death protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein YP_004369139.1 COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: dvl:Dvul_1364 histone family protein DNA-binding protein; PFAM: histone-like bacterial DNA-binding protein; SMART: histone-like bacterial DNA-binding protein; SPTR: histone family protein DNA-binding protein; PFAM: Bacterial DNA-binding protein YP_004369140.1 COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR014001:IPR001650:IPR006935; KEGG: dba:Dbac_1355 type III restriction protein res subunit; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: uncharacterized protein; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit YP_004369141.1 COGs: COG4710 DNA-binding protein with an HTH domain; InterPro IPR002145; KEGG: pla:Plav_1616 CopG/DNA-binding domain-containing protein; PFAM: CopG-like DNA-binding; SPTR: CopG domain protein DNA-binding domain protein; PFAM: Ribbon-helix-helix protein, copG family YP_004369142.1 KEGG: xfm:Xfasm12_1292 toxin-like protein; SPTR: Toxin-like protein YP_004369144.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: tye:THEYE_A1083 TonB-dependent receptor; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: TonB-dependent receptor; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004369145.1 InterPro IPR019613; KEGG: mpt:Mpe_A2803 ABC-type Co2+ transport system, periplasmic component; PFAM: Nickel transport complex, NikM subunit, transmembrane; SPTR: uncharacterized protein; PFAM: Nickel uptake substrate-specific transmembrane region YP_004369146.1 KEGG: dbr:Deba_1545 hypothetical protein; SPTR: uncharacterized protein YP_004369147.1 COGs: COG2875 Precorrin-4 methylase; InterPro IPR000878; KEGG: dae:Dtox_0475 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases YP_004369148.1 KEGG: dhd:Dhaf_3925 hypothetical protein; SPTR: uncharacterized protein; PFAM: Cytochrome b(N-terminal)/b6/petB YP_004369149.1 KEGG: adg:Adeg_1427 formate dehydrogenase, gamma subunit; SPTR: formate dehydrogenase, gamma subunit YP_004369150.1 COGs: COG4871 conserved hypothetical protein; InterPro IPR007202; KEGG: sfu:Sfum_3600 Fe-S cluster domain-containing protein; PFAM: Fe-S cluster; SPTR: Fe-S cluster domain protein; PFAM: Fe-S cluster YP_004369151.1 COGs: COG0394 protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: gme:Gmet_0521 protein tyrosine phosphatase; PFAM: protein-tyrosine phosphatase, low molecular weight; SMART: protein-tyrosine phosphatase, low molecular weight; SPTR: protein tyrosine phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase; TIGRFAM: arsenate reductase (thioredoxin) YP_004369152.1 COGs: COG0394 protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: sat:SYN_00054 phosphotyrosine protein phosphatase; PFAM: protein-tyrosine phosphatase, low molecular weight; SMART: protein-tyrosine phosphatase, low molecular weight; SPTR: phosphotyrosine protein phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase; TIGRFAM: arsenate reductase (thioredoxin) YP_004369153.1 InterPro IPR005243; KEGG: dba:Dbac_1903 redox-active disulfide protein 2; SPTR: Redox-active disulfide protein 2; TIGRFAM: Redox-active disulphide protein 2; TIGRFAM: small redox-active disulfide protein 2 YP_004369154.1 COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR007409:IPR005524; KEGG: dbr:Deba_2537 type I site-specific deoxyribonuclease, HsdR family; PFAM: protein of unknown function DUF318, transmembrane; Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; SPTR: Type I site-specific deoxyribonuclease, HsdR family; PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Predicted permease YP_004369155.1 COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356:IPR000055; KEGG: pca:Pcar_2925 type I restriction-modification system methyltransferase subunit; PFAM: DNA methylase, adenine-specific; Restriction endonuclease, type I, S subunit, EcoBI; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Type I restriction-modification system methyltransferase subunit; PFAM: N-6 DNA methylase; Type I restriction modification DNA specificity domain; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM) YP_004369156.1 COGs: COG3472 conserved hypothetical protein; InterPro IPR004919:IPR018651; KEGG: chd:Calhy_1152 hypothetical protein; PFAM: protein of unknown function DUF2081; Domain of unknown function DUF262; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2081); protein of unknown function DUF262 YP_004369157.1 COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356; KEGG: dbr:Deba_2542 type I restriction-modification system, M subunit; PFAM: DNA methylase, adenine-specific; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM) YP_004369158.1 KEGG: pbe:PB001621.02.0 hypothetical protein; SPTR: uncharacterized protein YP_004369159.1 COGs: COG5421 transposase; InterPro IPR002559; KEGG: acr:Acry_3223 transposase, IS4 family protein; PFAM: transposase, IS4-like; SPTR: transposase, IS4 family; PFAM: transposase DDE domain YP_004369161.1 KEGG: geo:Geob_2864 hypothetical protein; SPTR: uncharacterized protein YP_004369162.1 COGs: COG4584 transposase and inactivated derivatives; InterPro IPR001584; KEGG: mta:Moth_2239 integrase catalytic subunit; PFAM: Integrase, catalytic core; SPTR: Integrase, catalytic region; PFAM: Integrase core domain YP_004369163.1 COGs: COG1484 DNA replication protein; InterPro IPR003593:IPR002611; KEGG: mta:Moth_2240 IstB-like ATP-binding protein; PFAM: IstB-like ATP-binding protein; SMART: ATPase, AAA+ type, core; SPTR: IstB-like ATP-binding protein; PFAM: IstB-like ATP binding protein YP_004369164.1 KEGG: ptr:737059 hypothetical protein LOC737059; SPTR: MST148 protein YP_004369165.1 COGs: COG1468 RecB family exonuclease; InterPro IPR013343:IPR022765; KEGG: has:Halsa_1493 CRISPR-associated protein Cas4; PFAM: Dna2/Cas4, domain of unknown function DUF83; SPTR: CRISPR-associated protein Cas4; TIGRFAM: CRISPR-associated protein Cas4; PFAM: Domain of unknown function DUF83; TIGRFAM: CRISPR-associated protein Cas4 YP_004369166.1 KEGG: mae:Maeo_1069 hypothetical protein; SPTR: uncharacterized protein YP_004369167.1 InterPro IPR013422; KEGG: tye:THEYE_A1099 CRISPR-associated protein Cas5; SPTR: CRISPR-associated protein Cas5; TIGRFAM: CRISPR-associated protein Cas5, N-terminal domain; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, N-terminal domain YP_004369168.1 COGs: COG1857 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR010154; KEGG: tye:THEYE_A1098 crispr-associated autoregulator DevR family; SPTR: Crispr-associated autoregulator devr family; TIGRFAM: CRISPR-associated negative autoregulator; PFAM: CRISPR-associated negative autoregulator DevR/Csa2; TIGRFAM: CRISPR-associated autoregulator DevR family; CRISPR-associated protein Cas7/Csa2, subtype I-A/APERN YP_004369169.1 KEGG: tye:THEYE_A1096 CRISPR-associated protein, Csa5 family; SPTR: CRISPR-associated protein, Csa5 family YP_004369170.1 InterPro IPR006483; KEGG: tye:THEYE_A1089 CRISPR-associated HD domain protein; SPTR: CRISPR-associated HD domain protein; TIGRFAM: CRISPR-associated HD domain; TIGRFAM: CRISPR-associated endonuclease Cas3-HD YP_004369171.1 COGs: COG1203 helicase; InterPro IPR006474:IPR014001:IPR001650:IPR011545; KEGG: tye:THEYE_A1088 CRISPR-associated helicase Cas3; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: CRISPR-associated helicase Cas3; TIGRFAM: Helicase Cas3, CRISPR-associated, core; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3 YP_004369172.1 COGs: COG1343 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR021127; KEGG: dat:HRM2_05460 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: CRISPR associated protein Cas2; PFAM: CRISPR associated protein Cas2; TIGRFAM: CRISPR-associated endoribonuclease Cas2 YP_004369173.1 COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002729; KEGG: dat:HRM2_05450 CRISPR-associated protein (uncharacterized protein, predicted to be involved in DNA repair); PFAM: CRISPR-associated protein Cas1; SPTR: CRISPR-associated protein (Uncharacterized protein, predicted to be involved in DNA repair); TIGRFAM: CRISPR-associated protein Cas1; PFAM: CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated endonuclease Cas1 YP_004369174.1 COGs: COG2114 adenylate cyclase 3 (some protein contain HAMP domain); InterPro IPR001789:IPR001054; KEGG: ter:Tery_3999 adenylate/guanylate cyclase; PFAM: Signal transduction response regulator, receiver domain; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Signal transduction response regulator, receiver domain; adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: adenylate/guanylate cyclase; PFAM: adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain YP_004369175.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003018:IPR003661:IPR 003594:IPR001789:IPR008207:IPR013655:IPR013767; KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; PAS fold; GAF; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAC motif; PAS; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; SPTR: PAS fold family; TIGRFAM: PAS; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; Hpt domain; TIGRFAM: PAS domain S-box YP_004369176.1 COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR017476:IPR001732:IPR014026:IPR014027; KEGG: hya:HY04AAS1_0500 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase, central domain; UDP-glucose/GDP-mannose dehydrogenase, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase YP_004369177.1 COGs: COG1208 nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835; KEGG: dau:Daud_1040 nucleotidyl transferase; PFAM: nucleotidyl transferase; SPTR: nucleotidyl transferase; PFAM: nucleotidyl transferase YP_004369178.1 COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR017476:IPR001732:IPR014026:IPR014027; KEGG: chu:CHU_3394 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase, central domain; UDP-glucose/GDP-mannose dehydrogenase, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase YP_004369179.1 KEGG: sen:SACE_5017 acyl-CoA dehydrogenase; SPTR: acyl-CoA dehydrogenase YP_004369180.1 KEGG: sli:Slin_6475 hypothetical protein; SPTR: glucokinase YP_004369181.1 KEGG: smm:Smp_063680 hypothetical protein; SPTR: Prolipoprotein diacylglyceryl transferase YP_004369182.1 COGs: COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain; InterPro IPR006315:IPR005546:IPR008619; KEGG: bcm:Bcenmc03_5354 outer membrane autotransporter; PFAM: Autotransporter beta-domain; Filamentous haemagglutinin, bacterial; SMART: Autotransporter beta-domain; SPTR: Outer membrane autotransporter barrel domain protein; TIGRFAM: Outer membrane autotransporter barrel; PFAM: Autotransporter beta-domain YP_004369183.1 KEGG: dat:HRM2_29590 transposase (11 DDE domain protein); SPTR: transposase (11 DDE domain protein) YP_004369184.1 KEGG: gym:GYMC10_5346 hypothetical protein; SPTR: uncharacterized protein; PFAM: Coenzyme PQQ synthesis protein D (PqqD) YP_004369185.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR006638:IPR007197; KEGG: tne:Tneu_0969 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: radical SAM protein; PFAM: Radical SAM superfamily YP_004369186.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR006638:IPR007197; KEGG: rpd:RPD_4323 radical SAM family protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM additional 4Fe4S-binding domain YP_004369187.1 InterPro IPR011701; KEGG: nde:NIDE1691 MFS family permease; PFAM: Major facilitator superfamily MFS-1; SPTR: Permease, MFS family; PFAM: Bacterial protein of unknown function (DUF894) YP_004369188.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: mpi:Mpet_2793 type 12 methyltransferase; PFAM: methyltransferase type 11; SPTR: uncharacterized protein; PFAM: methyltransferase; TIGRFAM: methyltransferase, FkbM family YP_004369189.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910:IPR000531; KEGG: mch:Mchl_1472 TonB-dependent receptor plug; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; SPTR: TonB-dependent receptor plug; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004369190.1 COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: det:DET1494 peptide ABC transporter, periplasmic peptide-binding protein; PFAM: Bacterial extracellular solute-binding protein, family 5; SPTR: extracellular solute-binding protein, family 5; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004369191.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: dal:Dalk_0869 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: oligopeptide ABC transporter, permease; PFAM: Binding-protein-dependent transport system inner membrane component YP_004369192.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterProIPR010066:IPR003593:IPR000515:IPR003439:IPR 013563; KEGG: dal:Dalk_0870 binding-protein-dependent transport systems inner membrane component; PFAM: ABC transporter-like; Binding-protein-dependent transport systems inner membrane component; Oligopeptide/dipeptide ABC transporter, C-terminal; PRIAM: nickel ABC transporter ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; TIGRFAM: Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal; PFAM: ABC transporter; Binding-protein-dependent transport system inner membrane component; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004369193.1 COGs: COG1124 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: mtp:Mthe_1033 ABC transporter related; PFAM: ABC transporter-like; PRIAM: nickel ABC transporter ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter YP_004369194.1 COGs: COG1785 Alkaline phosphatase; InterPro IPR001952:IPR011449; KEGG: dly:Dehly_1316 alkaline phosphatase; PFAM: Alkaline phosphatase; PEP-CTERM bacterial; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; PFAM: Alkaline phosphatase YP_004369195.1 KEGG: dak:DaAHT2_2010 hypothetical protein; SPTR: uncharacterized protein YP_004369196.1 COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR004559:IPR006638:IPR007197:IPR010723; KEGG: sfu:Sfum_1360 oxygen-independent coproporphyrinogen III oxidase; PFAM: HemN, C-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Coproporphyrinogen III oxidase, anaerobic; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase YP_004369197.1 KEGG: gur:Gura_0379 hypothetical protein; SPTR: uncharacterized protein YP_004369198.1 COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR004879; KEGG: sti:Sthe_0131 protein of unknown function DUF255; SPTR: uncharacterized protein; PFAM: protein of unknown function, DUF255; glycosyl hydrolase 76 YP_004369199.1 InterPro IPR003115; KEGG: dol:Dole_2368 nuclease; SMART: ParB-like nuclease; SPTR: uncharacterized protein; PFAM: ParB-like nuclease domain YP_004369200.1 COGs: COG0767 ABC-type transport system involved in resistance to organic solvents permease component; InterPro IPR003453; KEGG: nde:NIDE1503 ABC transporter permease; PFAM: Domain of unknown function DUF140; SPTR: ABC transporter, permease component; PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein YP_004369201.1 KEGG: lhk:LHK_01395 sensor protein; SPTR: Sensor protein YP_004369202.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; KEGG: fno:Fnod_0450 extracellular solute-binding protein; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein YP_004369203.1 InterPro IPR011701; KEGG: chl:Chy400_3419 PucC protein; PFAM: Major facilitator superfamily MFS-1; SPTR: PUCC protein; PFAM: PUCC protein YP_004369204.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: npu:Npun_F2708 glycosyl transferase, group 1; PFAM: glycosyl transferase, group 1; SPTR: glycosyl transferase, group 1; PFAM: glycosyl transferases group 1 YP_004369205.1 KEGG: amd:AMED_2782 glycosyl transferase; SPTR: glycosyl transferase; manually curated YP_004369206.1 KEGG: mbu:Mbur_0397 hypothetical protein; SPTR: uncharacterized protein YP_004369207.1 KEGG: rme:Rmet_3071 histone H1-like protein; SPTR: histone H1-like protein HC2 YP_004369208.1 COGs: COG1362 aspartyl aminopeptidase; InterPro IPR001948; KEGG: dol:Dole_2226 aminopeptidase 1; PFAM: peptidase M18; PRIAM: aspartyl aminopeptidase; SPTR: M18 family aminopeptidase; PFAM: Aminopeptidase I zinc metalloprotease (M18) YP_004369209.1 KEGG: dal:Dalk_3243 hypothetical protein; SPTR: uncharacterized protein YP_004369210.1 KEGG: mbr:MONBRDRAFT_31889 hypothetical protein; SPTR: Uncharacterized protein YP_004369211.1 InterPro IPR000620; KEGG: smr:Smar_0375 hypothetical protein; PFAM: Drug/metabolite transporter; SPTR: uncharacterized protein; PFAM: EamA-like transporter family YP_004369212.1 COGs: COG1881 phospholipid-binding protein; InterPro IPR005247:IPR008914; KEGG: drt:Dret_1202 PEBP family protein; PFAM: phosphatidylethanolamine-binding protein PEBP; SPTR: PEBP family protein; TIGRFAM: YbhB/YbcL; PFAM: phosphatidylethanolamine-binding protein; TIGRFAM: Raf kinase inhibitor-like protein, YbhB/YbcL family YP_004369213.1 InterPro IPR014144; KEGG: mem:Memar_2179 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain YP_004369214.1 COGs: COG0102 ribosomal protein L13; InterPro IPR005823:IPR005822; KEGG: aac:Aaci_2680 ribosomal protein L13; PFAM: ribosomal protein L13; SPTR: ribosomal protein L13; TIGRFAM: ribosomal protein L13, bacterial-type; PFAM: ribosomal protein L13; TIGRFAM: ribosomal protein L13, bacterial type YP_004369215.1 COGs: COG0103 ribosomal protein S9; InterPro IPR000754; KEGG: pca:Pcar_1899 30S ribosomal protein S9; PFAM: ribosomal protein S9; SPTR: 30S ribosomal protein S9; PFAM: ribosomal protein S9/S16 YP_004369216.1 COGs: COG0002 Acetylglutamate semialdehyde dehydrogenase; HAMAP: N-acetyl-gamma-glutamyl-phosphate reductase, type 1; InterPro IPR000706:IPR000534:IPR012280; KEGG: sfu:Sfum_1667 N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: Semialdehyde dehydrogenase, NAD-binding; Semialdehyde dehydrogenase, dimerisation domain; PRIAM: N-acetyl-gamma-glutamyl-phosphate reductase; SMART: Semialdehyde dehydrogenase, NAD-binding; SPTR: N-acetyl-gamma-glutamyl-phosphate reductase; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase, type 1; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase, common form YP_004369217.1 COGs: COG0101 Pseudouridylate synthase; HAMAP: Pseudouridine synthase I, TruA; InterPro IPR001406:IPR020097; KEGG: pca:Pcar_1901 tRNA pseudouridine synthase A; PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; SPTR: tRNA pseudouridine synthase A; TIGRFAM: Pseudouridine synthase I, TruA; PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I YP_004369218.1 COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; InterPro IPR001279; KEGG: dat:HRM2_43600 metal-dependent hydrolase; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily YP_004369219.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR013656:IPR013767:IPR013655; KEGG: sfu:Sfum_0231 PAS/PAC sensor hybrid histidine kinase; PFAM: PAS fold-3; PAS fold-4; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; PAC motif; Signal transduction response regulator, receiver domain; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004369220.1 COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127; KEGG: adg:Adeg_1215 periplasmic solute binding protein; PFAM: ABC transporter metal-binding lipoprotein; SPTR: Periplasmic solute binding protein; PFAM: Periplasmic solute binding protein family YP_004369221.1 COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: mtp:Mthe_1103 ABC transporter related; PFAM: ABC transporter-like; PRIAM: phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter; PFAM: ABC transporter YP_004369222.1 COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: dau:Daud_1547 ABC-3 protein; PFAM: ABC-3; SPTR: ABC-3 protein; PFAM: ABC 3 transport family YP_004369223.1 COGs: COG3093 Plasmid maintenance system antidote protein; InterPro IPR013430:IPR001387; KEGG: nha:Nham_0579 XRE family plasmid maintenance system antidote protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: plasmid maintenance system antidote protein, XRE family; TIGRFAM: Addiction module antidote protein, HigA; PFAM: Helix-turn-helix; TIGRFAM: addiction module antidote protein, HigA family YP_004369224.1 KEGG: dat:HRM2_05930 flavodoxin family protein; SPTR: Flavodoxin family protein YP_004369225.1 KEGG: pfd:PFDG_02627 conserved hypothetical protein; SPTR: uncharacterized protein YP_004369226.1 InterPro IPR002048:IPR018248; KEGG: plm:Plim_3206 sulfatase; PFAM: EF-hand; SMART: Calcium-binding EF-hand; SPTR: Sulfatase; PFAM: EF hand YP_004369228.1 COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433:IPR019480; KEGG: dol:Dole_0316 ferredoxin-NADP(+) reductase subunit alpha; PFAM: Oxidoreductase FAD/NAD(P)-binding; dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain YP_004369229.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR006004:IPR013027; KEGG: dol:Dole_0317 glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: glutamate synthase (NADPH); SPTR: glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric YP_004369230.1 KEGG: dsa:Desal_3733 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: TIGR04076 family protein YP_004369231.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; HAMAP: Chaperone DnaJ; InterPro IPR012724:IPR001623:IPR001305:IPR002939; KEGG: tte:TTE0956 chaperone protein DnaJ; PFAM: Chaperone DnaJ, C-terminal; Heat shock protein DnaJ, N-terminal; Heat shock protein DnaJ, cysteine-rich domain; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Chaperone protein dnaJ; PFAM: DnaJ C terminal region; DnaJ central domain (4 repeats); DnaJ domain; TIGRFAM: chaperone protein DnaJ YP_004369232.1 InterPro IPR000551; KEGG: tye:THEYE_A1929 transcriptional regulator; PFAM: HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: uncharacterized protein YP_004369233.1 COGs: COG0658 membrane metal-binding protein; InterPro IPR004477; KEGG: gme:Gmet_1915 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; TIGRFAM: ComEC/Rec2-related protein YP_004369234.1 InterPro IPR013429; KEGG: gur:Gura_2431 FmdB family regulatory protein; PFAM: Regulatory protein, FmdB, SMART: Regulatory protein, FmdB, SPTR: regulatory protein, FmdB family; TIGRFAM: Regulatory protein, FmdB, PFAM: Zinc ribbon domain; TIGRFAM: regulatory protein, FmdB family YP_004369235.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: gme:Gmet_1376 outer membrane efflux protein; PFAM: Outer membrane efflux protein; SPTR: Outer membrane efflux protein; PFAM: Outer membrane efflux protein YP_004369236.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: cyt:cce_3303 glycosyl transferase; PFAM: glycosyl transferase, family 2; SPTR: glycosyl transferase 2; PFAM: glycosyl transferase 2 YP_004369237.1 KEGG: rso:RSc0614 hypothetical protein; SPTR: peptidyl-prolyl cis-trans isomerase; manually curated YP_004369238.1 KEGG: nhl:Nhal_3655 hypothetical protein; SPTR: uncharacterized protein YP_004369239.1 COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: dma:DMR_32970 cation efflux family protein; PFAM: Cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: Cation efflux protein; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_004369240.1 KEGG: dat:HRM2_38630 hypothetical protein; SPTR: uncharacterized protein YP_004369241.1 InterPro IPR011449; KEGG: ter:Tery_4344 hypothetical protein; PFAM: PEP-CTERM bacterial; SPTR: uncharacterized protein; PFAM: PEP-CTERM motif; TIGRFAM: PEP-CTERM exosortase interaction domain YP_004369242.1 COGs: COG2759 formyltetrahydrofolate synthetase; HAMAP: formate-tetrahydrofolate ligase, FTHFS; InterPro IPR000559; KEGG: sfu:Sfum_2687 formate--tetrahydrofolate ligase; PFAM: formate-tetrahydrofolate ligase, FTHFS; PRIAM: formate--tetrahydrofolate ligase; SPTR: formate--tetrahydrofolate ligase; PFAM: formate--tetrahydrofolate ligase YP_004369243.1 COGs: COG1142 Fe-S-cluster-containing hydrogenase components 2; InterPro IPR001450; KEGG: rru:Rru_A1426 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: 4Fe-4S binding domain; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: 4Fe-4S binding domain YP_004369244.1 COGs: COG1151 6Fe-6S prismane cluster-containing protein; InterPro IPR010047:IPR004137; KEGG: dat:HRM2_43440 Cdh2; PFAM: Prismane; PRIAM: Carbon-monoxide dehydrogenase (acceptor); SPTR: Cdh2; TIGRFAM: Carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane/CO dehydrogenase; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit YP_004369245.1 COGs: COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G); InterPro IPR001041:IPR001450; KEGG: mpl:Mpal_0845 ferredoxin; PFAM: 4Fe-4S binding domain; Ferredoxin; SPTR: Ferredoxin; PFAM: 2Fe-2S iron-sulfur cluster binding domain; 4Fe-4S binding domain YP_004369246.1 COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR005746:IPR013766; KEGG: dbr:Deba_1136 thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: Thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin YP_004369247.1 COGs: COG0492 Thioredoxin reductase; InterPro IPR005982:IPR013027; KEGG: chy:CHY_0906 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Thioredoxin-disulfide reductase; SPTR: Thioredoxin reductase; TIGRFAM: Thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase YP_004369248.1 COGs: COG4105 DNA uptake lipoprotein; InterPro IPR017689; KEGG: sat:SYN_00044 ComL family lipoprotein; SPTR: Lipoprotein, ComL family; TIGRFAM: Outer membrane assembly lipoprotein YfiO; TIGRFAM: outer membrane assembly lipoprotein YfiO YP_004369249.1 COGs: COG0496 acid phosphatase; HAMAP: Survival protein SurE-like phosphatase/nucleotidase; InterPro IPR002828; KEGG: sfu:Sfum_1169 stationary phase survival protein SurE; PFAM: Survival protein SurE-like phosphatase/nucleotidase; SPTR: 5'-nucleotidase surE; TIGRFAM: Survival protein SurE-like phosphatase/nucleotidase; PFAM: Survival protein SurE; TIGRFAM: 5'/3'-nucleotidase SurE YP_004369250.1 COGs: COG3876 conserved hypothetical protein; InterPro IPR001466:IPR008302; KEGG: aba:Acid345_2615 hypothetical protein; PFAM: Uncharacterised conserved protein UCP016719; Beta-lactamase-related; SPTR: uncharacterized protein; PFAM: Beta-lactamase; protein of unknown function (DUF1343) YP_004369251.1 COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR018320:IPR002421:IPR008918:IPR002562:IPR 001098:IPR020046:IPR020047; KEGG: dal:Dalk_2747 DNA polymerase I; PFAM: DNA-directed DNA polymerase, family A, palm domain; 5'-3' exonuclease, alpha-helical arch, N-terminal; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; SMART: 5'-3' exonuclease, N-terminal; Helix-hairpin-helix motif, class 2; 3'-5' exonuclease; DNA-directed DNA polymerase, family A, palm domain; SPTR: DNA polymerase I; TIGRFAM: DNA polymerase 1; PFAM: 5'-3' exonuclease, C-terminal SAM fold; 3'-5' exonuclease; DNA polymerase A; 5'-3' exonuclease, N-terminal resolvase-like domain; TIGRFAM: DNA polymerase I YP_004369252.1 KEGG: sfu:Sfum_0475 hypothetical protein; SPTR: uncharacterized protein YP_004369253.1 KEGG: tcr:504239.220 mucin-associated surface protein (MASP); SPTR: histone H1 YP_004369254.1 KEGG: rva:Rvan_0496 periplasmic binding protein; SPTR: Anhydro-N-acetylmuramic acid kinase YP_004369255.1 COGs: COG5621 secreted hydrolase; KEGG: nde:NIDE0517 hypothetical protein; SPTR: uncharacterized protein; PFAM: Hydroxyneurosporene synthase (CrtC) YP_004369256.1 KEGG: ure:UREG_01296 hypothetical protein; SPTR: uncharacterized protein YP_004369257.1 InterPro IPR019734:IPR006860:IPR001440:IPR011716; KEGG: neu:NE1298 TPR repeat-containing protein; PFAM: FecR protein; Tetratricopeptide TPR-1; Tetratricopeptide TPR-3; SPTR: Tetratricopeptide TPR_2 repeat protein; PFAM: FecR protein YP_004369258.1 COGs: COG0104 adenylosuccinate synthase; HAMAP: adenylosuccinate synthetase; InterPro IPR001114; KEGG: sfu:Sfum_1271 adenylosuccinate synthetase; PFAM: adenylosuccinate synthetase; PRIAM: adenylosuccinate synthase; SMART: adenylosuccinate synthetase; SPTR: adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthetase; PFAM: adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthase YP_004369259.1 COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR004399:IPR013749:IPR019293; KEGG: kcr:Kcr_0867 phosphomethylpyrimidine kinase; PFAM: phosphomethylpyrimidine kinase type-1; phosphomethylpyrimidine kinase; PRIAM: phosphomethylpyrimidine kinase; SPTR: phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase type-2; PFAM: phosphomethylpyrimidine kinase; Archaeal phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase YP_004369260.1 COGs: COG4784 Zn-dependent protease; InterPro IPR001915; KEGG: mmb:Mmol_0710 peptidase M48 Ste24p; PFAM: peptidase M48; SPTR: peptidase M48 Ste24p; PFAM: peptidase M48 YP_004369261.1 InterPro IPR019734:IPR001440; KEGG: gem:GM21_0276 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_2 repeat protein YP_004369262.1 COGs: COG1215 glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: fre:Franean1_3677 glycosyl transferase; PFAM: glycosyl transferase, family 2; SPTR: Cellulose synthase (UDP-forming); PFAM: glycosyl transferase 2; Cellulose synthase YP_004369263.1 COGs: COG1943 transposase and inactivated derivatives; KEGG: geo:Geob_3252 protein of unknown function DUF1568; SPTR: uncharacterized protein; PFAM: transposase IS200 like YP_004369264.1 InterPro IPR007730; KEGG: pin:Ping_0885 hypothetical protein; PFAM: Sporulation-related domain; SPTR: Genome sequencing data, contig C265; PFAM: Sporulation related domain YP_004369265.1 COGs: COG0348 polyferredoxin; InterPro IPR006311:IPR001450; KEGG: sat:SYN_02058 4Fe-4S binding protein; PFAM: 4Fe-4S binding domain; SPTR: 4Fe-4S binding protein; TIGRFAM: MauM/NapG family ferredoxin-type protein YP_004369266.1 COGs: COG2006 conserved hypothetical protein; InterPro IPR006311:IPR007160; KEGG: dol:Dole_0348 hypothetical protein; PFAM: Domain of unknown function DUF362; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF362); TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_004369267.1 COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterPro IPR013483:IPR006638:IPR007197:IPR010505; KEGG: dat:HRM2_35970 MoaA2; PFAM: Molybdenum cofactor synthesis C-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Molybdenum cofactor biosynthesis protein A 2; TIGRFAM: Molybdenum cofactor biosynthesis protein A; PFAM: Molybdenum Cofactor Synthesis C; Radical SAM superfamily; TIGRFAM: molybdenum cofactor biosynthesis protein A, bacterial YP_004369268.1 KEGG: mbu:Mbur_0753 ATP-dependent OLD family endonuclease; SPTR: uncharacterized protein YP_004369269.1 COGs: COG3093 Plasmid maintenance system antidote protein; InterPro IPR013430:IPR001387; KEGG: ana:asl2923 virulence-associated protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Virulence-associated protein; TIGRFAM: Addiction module antidote protein, HigA; PFAM: Helix-turn-helix; TIGRFAM: addiction module antidote protein, HigA family YP_004369270.1 COGs: COG3549 Plasmid maintenance system killer protein; InterPro IPR007711; KEGG: nha:Nham_4028 plasmid maintenance system killer; PFAM: Plasmid maintenance system killer; SPTR: Plasmid maintenance system killer; PFAM: Plasmid maintenance system killer protein YP_004369271.1 KEGG: ani:AN4533.2 hypothetical protein YP_004369272.1 COGs: COG0438 glycosyltransferase; InterPro IPR003141:IPR004013:IPR001296; KEGG: sfu:Sfum_2903 glycosyl transferase, group 1; PFAM: glycosyl transferase, group 1; PHP, C-terminal; SMART: polymerase/histidinol phosphatase, N-terminal; SPTR: glycosyltransferase, group 1 family protein; PFAM: PHP domain; glycosyl transferases group 1 YP_004369273.1 COGs: COG0688 phosphatidylserine decarboxylase; InterPro IPR003817; KEGG: sfu:Sfum_2902 phosphatidylserine decarboxylase-related; PFAM: phosphatidylserine decarboxylase-related; PRIAM: phosphatidylserine decarboxylase; SPTR: phosphatidylserine decarboxylase-related; PFAM: phosphatidylserine decarboxylase YP_004369274.1 KEGG: sfu:Sfum_2901 hypothetical protein; SPTR: uncharacterized protein YP_004369275.1 COGs: COG3176 hemolysin; InterPro IPR002123; KEGG: mgm:Mmc1_2481 phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: phospholipid/glycerol acyltransferase YP_004369276.1 KEGG: dat:HRM2_41340 hypothetical protein; SPTR: uncharacterized protein YP_004369277.1 KEGG: scl:sce2397 hypothetical protein; SPTR: uncharacterized protein YP_004369278.1 KEGG: nmu:Nmul_A0035 hypothetical protein; SPTR: uncharacterized protein YP_004369279.1 KEGG: nhl:Nhal_1385 hypothetical protein; SPTR: uncharacterized protein; PFAM: Heavy-metal-associated domain YP_004369280.1 KEGG: nhl:Nhal_1388 hypothetical protein; SPTR: uncharacterized protein YP_004369281.1 COGs: COG0474 Cation transport ATPase; InterProIPR001757:IPR004014:IPR008250:IPR005834:IPR 006068; KEGG: ava:Ava_4900 ATPase, E1-E2 type; PFAM: ATPase, P-type, ATPase-associated domain; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase; ATPase, P-type cation-transporter, C-terminal; PRIAM: Calcium-transporting ATPase; SMART: ATPase, P-type cation-transporter, N-terminal; SPTR: ATPase, E1-E2 type; TIGRFAM: ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehalogenase-like hydrolase; TIGRFAM: plasma-membrane calcium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004369282.1 COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133:IPR022628:IPR022629:IPR022630; KEGG: ana:all3244 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal; S-adenosylmethionine synthetase, N-terminal; S-adenosylmethionine synthetase, central domain; PRIAM: methionine adenosyltransferase; SPTR: S-adenosylmethionine synthetase (methionine adenosyltransferase) (AdoMet synthetase) (MAT); TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase YP_004369283.1 COGs: COG5379 S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase; KEGG: dma:DMR_27910 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3419) YP_004369284.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013217; KEGG: dma:DMR_27900 hypothetical protein; PFAM: methyltransferase type 12; SPTR: methyltransferase type 12; PFAM: methyltransferase domain YP_004369285.1 COGs: COG3604 transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR010113:IPR003018:IPR003593:IPR002078:IPR 002197; KEGG: dak:DaAHT2_1641 transcriptional regulator, NifA subfamily, fis family; PFAM: RNA polymerase sigma factor 54, interaction; GAF; Helix-turn-helix, Fis-type; SMART: GAF; ATPase, AAA+ type, core; SPTR: transcriptional regulator, NifA subfamily, Fis Family; TIGRFAM: Nif-specific regulatory protein; PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; TIGRFAM: Nif-specific regulatory protein YP_004369286.1 COGs: COG1970 Large-conductance mechanosensitive channel; HAMAP: Large-conductance mechanosensitive channel; InterPro IPR001185; KEGG: dbr:Deba_1460 large conductance mechanosensitive channel protein; PFAM: Large-conductance mechanosensitive channel; SPTR: Large-conductance mechanosensitive channel; TIGRFAM: Large-conductance mechanosensitive channel; PFAM: Large-conductance mechanosensitive channel, MscL; TIGRFAM: large conductance mechanosensitive channel protein YP_004369287.1 InterPro IPR016047; KEGG: dat:HRM2_23960 hypothetical protein; PFAM: peptidase M23; SPTR: uncharacterized protein; PFAM: peptidase M23 YP_004369288.1 COGs: COG3280 Maltooligosyl trehalose synthase; InterPro IPR012767:IPR006589:IPR006047; KEGG: mta:Moth_1811 malto-oligosyltrehalose synthase; PFAM: glycosyl hydrolase, family 13, catalytic domain; SMART: glycosyl hydrolase, family 13, subfamily, catalytic domain; SPTR: Malto-oligosyltrehalose synthase; TIGRFAM: Malto-oligosyltrehalose synthase; PFAM: Alpha amylase, catalytic domain; TIGRFAM: malto-oligosyltrehalose synthase YP_004369289.1 COGs: COG1449 Alpha-amylase/alpha-mannosidase; InterPro IPR004300; KEGG: mta:Moth_1810 glycoside hydrolase; PFAM: glycoside hydrolase, family 57, N-terminal; SPTR: glycoside hydrolase, family 57; PFAM: glycosyl hydrolase 57; Domain of unknown function (DUF3536) YP_004369290.1 COGs: COG0296 1 4-alpha-glucan branching enzyme; InterPro IPR012768:IPR006589:IPR004193:IPR006047; KEGG: mta:Moth_1809 malto-oligosyltrehalose trehalohydrolase; PFAM: glycosyl hydrolase, family 13, catalytic domain; glycoside hydrolase, family 13, N-terminal; PRIAM: 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase; SMART: glycosyl hydrolase, family 13, subfamily, catalytic domain; SPTR: Malto-oligosyltrehalose trehalohydrolase; TIGRFAM: Malto-oligosyltrehalose trehalohydrolase; PFAM: Alpha amylase, catalytic domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); TIGRFAM: malto-oligosyltrehalose trehalohydrolase YP_004369291.1 KEGG: rca:Rcas_0525 TPR repeat-containing serine/threonin protein kinase; SPTR: Serine/threonine protein kinase with TPR repeats YP_004369292.1 KEGG: dak:DaAHT2_2418 hypothetical protein; SPTR: uncharacterized protein YP_004369293.1 COGs: COG2114 adenylate cyclase 3 (some protein contain HAMP domain); InterPro IPR001054:IPR007890; KEGG: gur:Gura_0668 adenylate/guanylate cyclase; PFAM: CHASE2; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: adenylate/guanylate cyclase; PFAM: adenylate and Guanylate cyclase catalytic domain; CHASE2 domain YP_004369294.1 InterPro IPR013247; KEGG: tye:THEYE_A0776 hypothetical protein; PFAM: SH3, type 3; SPTR: uncharacterized protein; PFAM: Bacterial SH3 domain YP_004369295.1 COGs: COG4783 Zn-dependent protease contains TPR repeats; InterPro IPR001915; KEGG: geo:Geob_0884 peptidase M48 Ste24p; PFAM: peptidase M48; SPTR: peptidase M48 Ste24p; PFAM: peptidase M48 YP_004369296.1 COGs: COG3857 ATP-dependent nuclease subunit B; KEGG: sfu:Sfum_0479 ATP-dependent nuclease subunit B-like; SPTR: ATP-dependent nuclease subunit B-like YP_004369297.1 COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR000212; KEGG: sfu:Sfum_1741 UvrD/REP helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: DNA helicase/exodeoxyribonuclease V, subunit A; PFAM: UvrD/REP helicase YP_004369298.1 COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005785:IPR001544; KEGG: dvl:Dvul_0190 branched-chain amino acid aminotransferase; PFAM: Aminotransferase, class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched chain amino acid aminotransferase / branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase; TIGRFAM: Branched-chain amino acid aminotransferase I; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group I YP_004369301.1 COGs: COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain; InterPro IPR006315:IPR005546; KEGG: mmr:Mmar10_0263 hypothetical protein; PFAM: Autotransporter beta-domain; SMART: Autotransporter beta-domain; SPTR: uncharacterized protein; TIGRFAM: Outer membrane autotransporter barrel YP_004369302.1 KEGG: dar:Daro_0245 outer membrane autotransporter barrel; SPTR: Outer membrane autotransporter barrel YP_004369303.1 InterPro IPR003644; KEGG: meh:M301_0718 outer membrane adhesin like protein; PFAM: Na-Ca exchanger/integrin-beta4; SMART: Na-Ca exchanger/integrin-beta4; SPTR: Secreted protein; PFAM: Calx-beta domain YP_004369304.1 KEGG: eli:ELI_02045 hypothetical protein; SPTR: uncharacterized protein YP_004369305.1 InterPro IPR002509; KEGG: bbe:BBR47_42490 hypothetical protein; PFAM: polysaccharide deacetylase; SPTR: uncharacterized protein; PFAM: polysaccharide deacetylase YP_004369306.1 KEGG: bbe:BBR47_42510 hypothetical protein; SPTR: uncharacterized protein YP_004369307.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: paa:Paes_0353 glycosyl transferase 2; PFAM: glycosyl transferase, family 2; SPTR: glycosyl transferase 2; PFAM: glycosyl transferase 2 YP_004369308.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: ank:AnaeK_4421 glycosyl transferase group 1; PFAM: glycosyl transferase, group 1; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1 YP_004369309.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: npu:Npun_F2442 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein YP_004369310.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104:IPR001451; KEGG: dbr:Deba_2421 oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; Bacterial transferase hexapeptide repeat; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold; Bacterial transferase hexapeptide (three repeats) YP_004369311.1 COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476:IPR001732:IPR014026:IPR014027; KEGG: gur:Gura_1673 UDP-glucose/GDP-mannose dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: Similar to UDP-glucose/GDP-mannose dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase, central domain; UDP-glucose/GDP-mannose dehydrogenase, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase YP_004369312.1 COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: gme:Gmet_2330 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-glucuronate 5'-epimerase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase YP_004369313.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: llo:LLO_0936 nucleoside-diphosphate sugar epimerases; PFAM: polysaccharide biosynthesis protein CapD-like; SPTR: nucleoside-diphosphate sugar epimerases; PFAM: polysaccharide biosynthesis protein YP_004369314.1 InterPro IPR013426:IPR014263:IPR019127; KEGG: nde:NIDE2403 hypothetical protein; PFAM: Exosortase EpsH-related; SPTR: uncharacterized protein; TIGRFAM: Exosortase, EpsH; methanolan biosynthesis EpsI; PFAM: protein of unknown function (DUF3485); transmembrane exosortase (Exosortase_EpsH); TIGRFAM: EpsI family protein; eight transmembrane protein EpsH (proposed exosortase) YP_004369315.1 COGs: COG1045 Serine acetyltransferase; InterPro IPR020019:IPR001451; KEGG: aar:Acear_2113 sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; SPTR: Sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; TIGRFAM: Sialic acid O-acyltransferase, NeuD; TIGRFAM: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family YP_004369316.1 KEGG: cth:Cthe_2342 hypothetical protein; SPTR: uncharacterized protein; PFAM: FemAB family YP_004369317.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: nde:NIDE2685 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase YP_004369318.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: hau:Haur_3873 undecaprenyl-phosphate galactose phosphotransferase; PFAM: Bacterial sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Undecaprenyl-phosphate galactose phosphotransferase; PFAM: Bacterial sugar transferase YP_004369319.1 COGs: COG3267 Type II secretory pathway component ExeA (predicted ATPase); InterPro IPR003593; KEGG: dba:Dbac_2582 AAA ATPase; SMART: ATPase, AAA+ type, core; SPTR: Secretion ATPase, PEP-CTERM locus subfamily; PFAM: Archaeal ATPase; TIGRFAM: secretion ATPase, PEP-CTERM locus subfamily YP_004369320.1 COGs: COG0489 ATPase involved in chromosome partitioning; KEGG: dsa:Desal_2423 capsular exopolysaccharide family; SPTR: Capsular exopolysaccharide family; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: exopolysaccharide/PEPCTERM locus tyrosine autokinase; capsular exopolysaccharide family YP_004369321.1 COGs: COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis; InterPro IPR003856; KEGG: dsa:Desal_2424 lipopolysaccharide biosynthesis protein; PFAM: Lipopolysaccharide biosynthesis; SPTR: uncharacterized protein; PFAM: Chain length determinant protein YP_004369322.1 KEGG: sat:SYN_00781 hypothetical protein; SPTR: Hypothetical exported protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2320); TIGRFAM: uncharacterized protein, PEP-CTERM system associated YP_004369323.1 COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR003715:IPR019554; KEGG: nde:NIDE2406 polysaccharide export protein (fragment); PFAM: polysaccharide export protein; Soluble ligand binding domain; SPTR: polysaccharide export protein; PFAM: polysaccharide biosynthesis/export protein; SLBB domain YP_004369324.1 COGs: COG0693 intracellular protease/amidase; InterPro IPR006286:IPR002818; KEGG: sus:Acid_5493 PfpI family intracellular peptidase; PFAM: ThiJ/PfpI; SPTR: Intracellular protease, PfpI family; TIGRFAM: peptidase C56, PfpI; PFAM: DJ-1/PfpI family; TIGRFAM: intracellular protease, PfpI family YP_004369325.1 COGs: COG0022 pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475:IPR005476; KEGG: amt:Amet_1252 transketolase, central region; PFAM: transketolase-like, pyrimidine-binding domain; transketolase, C-terminal; PRIAM: pyruvate dehydrogenase (acetyl-transferring); SMART: transketolase-like, pyrimidine-binding domain; SPTR: transketolase, central region; PFAM: transketolase, C-terminal domain; transketolase, pyrimidine binding domain YP_004369326.1 COGs: COG1071 pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR017596:IPR001017; KEGG: amt:Amet_1251 pyruvate dehydrogenase (acetyl-transferring); PFAM: Dehydrogenase, E1 component; PRIAM: pyruvate dehydrogenase (acetyl-transferring); SPTR: pyruvate dehydrogenase (Acetyl-transferring); TIGRFAM: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x; PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit YP_004369327.1 KEGG: cme:CMR441C hypothetical protein, conserved; SPTR: uncharacterized protein; PFAM: Thioredoxin YP_004369328.1 COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterProIPR014284:IPR012845:IPR007627:IPR007624:IPR 007630; KEGG: dak:DaAHT2_1725 RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 3; RNA polymerase sigma-70 region 4; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG; RNA polymerase sigma-70; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family YP_004369329.1 COGs: COG0455 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: dbr:Deba_2321 cobyrinic acid ac-diamide synthase; PFAM: cobyrinic acid a,c-diamide synthase; SPTR: cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004369330.1 COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006153:IPR003148; KEGG: sfu:Sfum_2433 sodium/hydrogen exchanger; PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; SPTR: Sodium/hydrogen exchanger; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family YP_004369331.1 InterPro IPR007922; KEGG: gsu:GSU0638 hypothetical protein; PFAM: protein of unknown function DUF721/UPF0232; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF721) YP_004369332.1 COGs: COG0215 cysteinyl-tRNA synthetase; InterPro IPR015803:IPR015273; KEGG: ppd:Ppro_0031 cysteinyl-tRNA synthetase; PFAM: cysteinyl-tRNA synthetase, class Ia; cysteinyl-tRNA synthetase, class Ia, DALR; PRIAM: cysteine--tRNA ligase; SMART: cysteinyl-tRNA synthetase, class Ia, DALR; SPTR: cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase, class Ia; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase YP_004369333.1 KEGG: pcs:Pc22g03720 Pc22g03720; SPTR: uncharacterized protein YP_004369334.1 COGs: COG1215 glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: fjo:Fjoh_4840 hyaluronan synthase; PFAM: glycosyl transferase, family 2; PRIAM: Hyaluronan synthase; SPTR: Candidate beta-glycosyltransferase; glycosyltransferase 2; PFAM: glycosyl transferase 2 YP_004369335.1 COGs: COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; KEGG: adg:Adeg_0900 formyl transferase domain protein; SPTR: formyl transferase domain protein; PFAM: formyl transferase YP_004369336.1 COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: cac:CA_C0230 hypothetical protein; PFAM: peptidase U62, modulator of DNA gyrase; SPTR: uncharacterized protein; PFAM: modulator of DNA gyrase YP_004369337.1 KEGG: sfu:Sfum_2878 hypothetical protein; SPTR: uncharacterized protein YP_004369338.1 InterPro IPR003425; KEGG: dol:Dole_3054 protein of unknown function YGGT; PFAM: Uncharacterised protein family Ycf19; SPTR: YGGT family protein; PFAM: YGGT family YP_004369339.1 InterPro IPR019933:IPR007793; KEGG: pca:Pcar_0616 cell division initiation protein, DivIVA-like; PFAM: DivIVA; SPTR: Cell division initiation protein, DivIVA-like; TIGRFAM: DivIVA domain; PFAM: DivIVA protein; TIGRFAM: DivIVA domain YP_004369340.1 COGs: COG1872 conserved hypothetical protein; HAMAP: protein of unknown function DUF167; InterPro IPR003746; KEGG: lhk:LHK_03181 hypothetical protein; PFAM: protein of unknown function DUF167; SPTR: UPF0235 protein LHK_03181; PFAM: Uncharacterised ACR, YggU family COG1872; TIGRFAM: TIGR00251 family protein YP_004369341.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; HAMAP: Chaperone DnaJ; InterPro IPR012724:IPR001623:IPR001305:IPR002939; KEGG: sfu:Sfum_1756 chaperone protein DnaJ; PFAM: Chaperone DnaJ, C-terminal; Heat shock protein DnaJ, N-terminal; Heat shock protein DnaJ, cysteine-rich domain; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Chaperone protein dnaJ; TIGRFAM: Chaperone DnaJ; PFAM: DnaJ C terminal region; DnaJ central domain (4 repeats); DnaJ domain; TIGRFAM: chaperone protein DnaJ YP_004369342.1 COGs: COG0556 Helicase subunit of the DNA excision repair complex; HAMAP: Excinuclease ABC, B subunit; InterProIPR004807:IPR014001:IPR001650:IPR006935:IPR 001943; KEGG: sat:SYN_00609 excinuclease ABC subunit B; PFAM: Helicase, C-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; UvrB/UvrC protein; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: UvrABC system protein B; TIGRFAM: Excinuclease ABC, B subunit; PFAM: Helicase conserved C-terminal domain; UvrB/uvrC motif; Type III restriction enzyme, res subunit; Ultra-violet resistance protein B; TIGRFAM: excinuclease ABC, B subunit YP_004369343.1 InterPro IPR013429; KEGG: dbr:Deba_0447 regulatory protein FmdB; PFAM: Regulatory protein, FmdB, SMART: Regulatory protein, FmdB, SPTR: regulatory protein FmdB; PFAM: Zinc ribbon domain; TIGRFAM: regulatory protein, FmdB family YP_004369344.1 COGs: COG0150 phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR004733:IPR000728:IPR010918; KEGG: sfu:Sfum_3278 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; PRIAM: phosphoribosylformylglycinamidine cyclo-ligase; SPTR: phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase YP_004369345.1 COGs: COG1342 DNA-binding protein; HAMAP: Uncharacterised protein family UPF0251; InterPro IPR002852; KEGG: dat:HRM2_31170 hypothetical protein; PFAM: Uncharacterised protein family UPF0251; SPTR: UPF0251 protein HRM2_31170; manually curated; PFAM: protein of unknown function DUF134 YP_004369346.1 COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR011270:IPR011268:IPR000845; KEGG: rmr:Rmar_2166 purine nucleoside phosphorylase I, inosine and guanosine-specific; PFAM: nucleoside phosphorylase domain; PRIAM: Purine-nucleoside phosphorylase; SPTR: Purine nucleoside phosphorylase I, inosine and guanosine-specific; TIGRFAM: Purine nucleoside phosphorylase I, inosine/guanosine-specific; Inosine guanosine/xanthosine phosphorylase; PFAM: phosphorylase superfamily; TIGRFAM: purine nucleoside phosphorylase I, inosine and guanosine-specific; inosine guanosine and xanthosine phosphorylase YP_004369347.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764; KEGG: dak:DaAHT2_2367 glycoside hydrolase 3 domain protein; PFAM: glycoside hydrolase, family 3, N-terminal; SPTR: beta-N-acetylglucosaminidase; PFAM: glycosyl hydrolase 3 N terminal domain YP_004369348.1 KEGG: bae:BATR1942_11555 bifunctional preprotein translocase subunit SecD/SecF; SPTR: Sec-independent protein translocase, TatC subunit YP_004369349.1 COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR014732:IPR001754; KEGG: dbr:Deba_2896 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase domain; PRIAM: Orotidine-5'-phosphate decarboxylase; SMART: Orotidine 5'-phosphate decarboxylase domain; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 1 YP_004369350.1 COGs: COG2271 Sugar phosphate permease; InterPro IPR011701; KEGG: gme:Gmet_3221 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004369351.1 COGs: COG0344 membrane protein; HAMAP: glycerol-3-phosphate acyltransferase, bacteria; InterPro IPR003811; KEGG: gur:Gura_3922 membrane protein; PFAM: glycerol-3-phosphate acyltransferase, bacteria; SPTR: acyl-phosphate glycerol-3-phosphate acyltransferase; TIGRFAM: glycerol-3-phosphate acyltransferase, bacteria; PFAM: Domain of unknown function (DUF205); TIGRFAM: acyl-phosphate glycerol 3-phosphate acyltransferase YP_004369352.1 COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR000644:IPR002912; KEGG: dbr:Deba_2745 signal transduction protein with CBS domains; PFAM: cystathionine beta-synthase, core; Amino acid-binding ACT; SMART: cystathionine beta-synthase, core; SPTR: signal transduction protein with CBS domains; PFAM: CBS domain; ACT domain YP_004369353.1 KEGG: gbm:Gbem_2647 hypothetical protein; SPTR: uncharacterized protein YP_004369354.1 COGs: COG0591 Na+/proline symporter; InterPro IPR003018:IPR003661:IPR003594:IPR001789; KEGG: geo:Geob_2606 protein serine phosphatase with GAF(s) sensor(s); PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SPTR: GAF sensor signal transduction histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain YP_004369355.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR001789:IPR003661:IPR003594; KEGG: tye:THEYE_A1337 two-component hybrid sensor and regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; SPTR: Two-component hybrid sensor and regulator; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain YP_004369356.1 COGs: COG2951 Membrane-bound lytic murein transglycosylase B; KEGG: dat:HRM2_03970 MltB; SPTR: MltB YP_004369357.1 COGs: COG0041 phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; InterPro IPR000031; KEGG: mgm:Mmc1_3464 phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: phosphoribosylaminoimidazole carboxylase, core; PRIAM: phosphoribosylaminoimidazole carboxylase; SPTR: phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, core; PFAM: AIR carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurE protein YP_004369358.1 COGs: COG0787 Alanine racemase; HAMAP: Alanine racemase; InterPro IPR000821:IPR001608:IPR011079; KEGG: hor:Hore_01680 alanine racemase; PFAM: Alanine racemase, N-terminal; Alanine racemase, C-terminal; PRIAM: Alanine racemase; SPTR: Alanine racemase; TIGRFAM: Alanine racemase; PFAM: Alanine racemase, C-terminal domain; Alanine racemase, N-terminal domain; TIGRFAM: alanine racemase YP_004369359.1 KEGG: tye:THEYE_A0347 hypothetical protein; SPTR: uncharacterized protein YP_004369360.1 InterPro IPR013216; KEGG: min:Minf_1771 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase; PFAM: methyltransferase type 11; SPTR: 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase; PFAM: methyltransferase domain YP_004369361.1 COGs: COG0018 arginyl-tRNA synthetase; HAMAP: arginyl-tRNA synthetase, class Ic; InterPro IPR001278:IPR008909:IPR005148:IPR015945; KEGG: gbm:Gbem_2283 arginyl-tRNA synthetase; PFAM: arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase, class Ic, N-terminal; DALR anticodon binding; PRIAM: arginine--tRNA ligase; SMART: DALR anticodon binding; SPTR: arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase, class Ic; PFAM: DALR anticodon binding domain; arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase YP_004369362.1 InterPro IPR007730; KEGG: dma:DMR_23310 hypothetical membrane protein; PFAM: Sporulation-related domain; SPTR: Hypothetical membrane protein; PFAM: Sporulation related domain YP_004369363.1 COGs: COG0118 glutamine amidotransferase; HAMAP: Imidazole glycerol phosphate synthase, subunit H; InterPro IPR010139:IPR000991; KEGG: dbr:Deba_1439 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: glutamine amidotransferase class-I, C-terminal; SPTR: Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; TIGRFAM: Imidazole glycerol phosphate synthase, subunit H; PFAM: glutamine amidotransferase class-I; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit YP_004369364.1 COGs: COG0107 Imidazoleglycerol-phosphate synthase; HAMAP: histidine biosynthesis, HisF; InterPro IPR004651:IPR006062; KEGG: sfu:Sfum_0483 imidazole glycerol phosphate synthase subunit HisF; PFAM: histidine biosynthesis; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidazole-4-carboxamideisomerase; SPTR: Imidazole glycerol phosphate synthase subunit hisF; TIGRFAM: histidine biosynthesis, HisF; PFAM: histidine biosynthesis protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit YP_004369365.1 COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterPro IPR014284:IPR009042:IPR007627:IPR007630; KEGG: sfu:Sfum_2115 sigma-70 region 2 domain-containing protein; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 1.2; RNA polymerase sigma-70 region 4; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-70; PFAM: Sigma-70, region 4; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; alternative sigma factor RpoH YP_004369366.1 InterPro IPR019734:IPR013105:IPR001440; KEGG: sfu:Sfum_0074 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: TPR repeat-containing protein; PFAM: Tetratricopeptide repeat YP_004369367.1 KEGG: pca:Pcar_1871 hypothetical protein; SPTR: uncharacterized protein YP_004369368.1 COGs: COG1656 conserved hypothetical protein; InterPro IPR002782; KEGG: abi:Aboo_0341 protein of unknown function DUF82; PFAM: protein of unknown function DUF82; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF82 YP_004369369.1 KEGG: ppp:PHYPADRAFT_187677 hypothetical protein; SPTR: Predicted protein YP_004369370.1 KEGG: pgn:PGN_1899 hypothetical protein; SPTR: uncharacterized protein YP_004369371.1 COGs: COG0574 phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279; KEGG: tye:THEYE_A0726 probable phosphoenolpyruvate synthase; PFAM: pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile domain; PRIAM: pyruvate, water dikinase; SPTR: Probable phosphoenolpyruvate synthase; PFAM: PEP-utilising enzyme, mobile domain; pyruvate phosphate dikinase, PEP/pyruvate binding domain YP_004369372.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: tye:THEYE_A0725 FrgC; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: FrgC; PFAM: Response regulator receiver domain YP_004369373.1 COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR000014:IPR003661:IPR003594:IPR013656; KEGG: tye:THEYE_A0724 sensory box sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Sensory box sensor histidine kinase; TIGRFAM: PAS; PFAM: Cache domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004369374.1 KEGG: sar:SAR0781 proton-dependent oligopeptide transport protein YP_004369376.1 COGs: COG0288 Carbonic anhydrase; InterPro IPR001765; KEGG: geo:Geob_2807 carbonic anhydrase; PFAM: Carbonic anhydrase; SMART: Carbonic anhydrase; SPTR: Carbonic anhydrase; PFAM: Carbonic anhydrase YP_004369377.1 COGs: COG1109 phosphomannomutase; InterProIPR006352:IPR005844:IPR005845:IPR005846:IPR 005843; KEGG: gme:Gmet_1886 phosphoglucosamine mutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; PRIAM: phosphoglucosamine mutase; SPTR: phosphoglucosamine mutase; TIGRFAM: phosphoglucosamine mutase; PFAM: phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase, C-terminal domain; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucosamine mutase YP_004369378.1 COGs: COG1521 transcriptional regulator protein; HAMAP: Type III pantothenate kinase; InterPro IPR004619; KEGG: sfu:Sfum_0549 pantothenate kinase; PFAM: Type III pantothenate kinase; SPTR: Type III pantothenate kinase; TIGRFAM: Type III pantothenate kinase; PFAM: Bordetella pertussis Bvg accessory factor family; TIGRFAM: pantothenate kinase, type III YP_004369379.1 COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: mau:Micau_4387 ABC transproter-like protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter YP_004369380.1 COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: sth:STH824 branched chain amino acid ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Branched chain amino acid ABC transporter ATP-binding protein; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004369381.1 COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: sfu:Sfum_3103 inner-membrane translocator; PFAM: ABC transporter permease; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component YP_004369382.1 KEGG: dda:Dd703_0202 ATP-dependent RNA helicase RhlB YP_004369383.1 COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR003953:IPR001450; KEGG: sfu:Sfum_3133 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; 4Fe-4S binding domain; SPTR: uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004369384.1 COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: dbr:Deba_2151 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase, delta subunit; SPTR: F420-non-reducing hydrogenase vhu iron-sulfur subunit D; PFAM: methyl-viologen-reducing hydrogenase, delta subunit YP_004369385.1 KEGG: dbr:Deba_2152 hypothetical protein; SPTR: uncharacterized protein; PFAM: methylene-tetrahydrofolate reductase C terminal YP_004369386.1 COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: dol:Dole_1151 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: uncharacterized protein; PFAM: methylenetetrahydrofolate reductase YP_004369387.1 COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: dma:DMR_12070 ABC transporter permease; PFAM: ABC transporter permease; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component YP_004369388.1 COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: sfu:Sfum_3105 extracellular ligand-binding receptor; PFAM: Extracellular ligand-binding receptor; SPTR: Extracellular ligand-binding receptor; PFAM: Receptor family ligand binding region YP_004369389.1 COGs: COG4957 transcriptional regulator protein; InterPro IPR008807; KEGG: gsu:GSU1863 Ros/MucR family transcriptional regulator; PFAM: ROSMUCR transcriptional regulator; SPTR: transcriptional regulator, Ros/MucR family; PFAM: ROS/MUCR transcriptional regulator protein YP_004369390.1 COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; HAMAP: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; InterProIPR005146:IPR005147:IPR005121:IPR004532:IPR 002547; KEGG: sfu:Sfum_0429 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/B4 tRNA-binding domain; tRNA-binding domain; tRNA synthetase, B5; Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding; SMART: B3/B4 tRNA-binding domain; tRNA synthetase, B5; Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial YP_004369391.1 InterPro IPR000551; KEGG: sus:Acid_0018 MerR family transcriptional regulator; PFAM: HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Regulatory protein, MerR; PFAM: MerR family regulatory protein YP_004369392.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: nhl:Nhal_0824 efflux transporter, RND family, MFP subunit; PFAM: Secretion protein HlyD; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004369393.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: mca:MCA2152 AcrB/AcrD/AcrF family protein; PFAM: Acriflavin resistance protein; SPTR: AcrB/AcrD/AcrF family protein; PFAM: AcrB/AcrD/AcrF family YP_004369394.1 InterPro IPR001450; KEGG: drt:Dret_0154 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain YP_004369395.1 KEGG: tye:THEYE_A0985 dissimilatory siroheme-sulfite reductase, gamma subunit-like protein; SPTR: Dissimilatory siroheme-sulfite reductase, gamma subunit-like protein YP_004369396.1 COGs: COG1194 A/G-specific DNA glycosylase; InterPro IPR003265; KEGG: mem:Memar_1721 HhH-GPD family protein; PFAM: HhH-GPD domain; SMART: HhH-GPD domain; SPTR: HhH-GPD family protein; PFAM: HhH-GPD superfamily base excision DNA repair protein; Helix-hairpin-helix motif YP_004369397.1 COGs: COG1001 adenine deaminase; HAMAP: adenine deaminase; InterPro IPR006679:IPR006680; KEGG: tjr:TherJR_1315 adenine deaminase; PFAM: Amidohydrolase 1; PRIAM: adenine deaminase; SPTR: adenine deaminase; TIGRFAM: adenine deaminase; PFAM: Amidohydrolase; TIGRFAM: adenine deaminase YP_004369398.1 InterPro IPR007197; KEGG: sfu:Sfum_1766 radical SAM domain-containing protein; PFAM: Radical SAM; SPTR: radical SAM protein; PFAM: Radical SAM superfamily YP_004369399.1 COGs: COG2423 ornithine cyclodeaminase mu-crystallin homolog; InterPro IPR003462; KEGG: apo:Arcpr_1568 alanine dehydrogenase; PFAM: ornithine cyclodeaminase/mu-crystallin; PRIAM: ornithine cyclodeaminase; SPTR: Alanine dehydrogenase; PFAM: ornithine cyclodeaminase/mu-crystallin family; TIGRFAM: alanine dehydrogenase, Archaeoglobus fulgidus type YP_004369400.1 COGs: COG0166 glucose-6-phosphate isomerase; HAMAP: phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: hor:Hore_19060 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase YP_004369401.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: sfu:Sfum_0854 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004369402.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: dak:DaAHT2_1070 two component, sigma54 specific, transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: fused DNA-binding response regulator in two-component regulatory system with ZraS: response regulator/sigma54 interaction protein; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004369403.1 COGs: COG0498 Threonine synthase; InterPro IPR004450:IPR001926; KEGG: dal:Dalk_4397 threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Threonine synthase; SPTR: Threonine synthase; TIGRFAM: Threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase YP_004369404.1 COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763:IPR013027:IPR004099; KEGG: sfu:Sfum_4025 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain YP_004369405.1 COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR022689:IPR007167:IPR022687:IPR001367; KEGG: dak:DaAHT2_0358 iron (metal) dependent repressor, DtxR family; PFAM: Ferrous iron transporter, FeoA subunit; Iron dependent repressor; Iron dependent repressor, N-terminal; SMART: Iron dependent repressor, diptheria toxin type; Ferrous iron transporter, FeoA subunit; SPTR: uncharacterized protein; PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain YP_004369406.1 COGs: COG1918 Fe2+ transport system protein A; InterPro IPR007167; KEGG: tit:Thit_1666 FeoA family protein; PFAM: Ferrous iron transporter, FeoA subunit; SMART: Ferrous iron transporter, FeoA subunit; SPTR: uncharacterized protein; PFAM: FeoA domain YP_004369407.1 COGs: COG0370 Fe2+ transport system protein B; InterProIPR005225:IPR003373:IPR002917:IPR011619:IPR 011642:IPR011640; KEGG: vpr:Vpar_0632 ferrous iron transport protein B; PFAM: Ferrous iron transport protein B, N-terminal; GTP-binding protein, HSR1-related; nucleoside recognition; Ferrous iron transport protein B, C-terminal; SPTR: Ferrous iron transport protein B; TIGRFAM: Ferrous iron transport protein B; Small GTP-binding protein; PFAM: Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB; small GTP-binding protein domain YP_004369408.1 KEGG: gur:Gura_2221 hypothetical protein; SPTR: uncharacterized protein YP_004369409.1 KEGG: ere:EUBREC_1386 glycosyl hydrolase, family 53; SPTR: uncharacterized protein YP_004369410.1 KEGG: dps:DP0333 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2325) YP_004369411.1 KEGG: rno:303499 Sp2 transcription factor; SPTR: uncharacterized protein YP_004369412.1 KEGG: dbr:Deba_0447 regulatory protein FmdB; SPTR: regulatory protein FmdB YP_004369413.1 KEGG: cak:Caul_4070 hypothetical protein; SPTR: uncharacterized protein YP_004369414.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: sfu:Sfum_0492 TonB-dependent receptor; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: uncharacterized protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004369415.1 InterPro IPR017199; KEGG: ppd:Ppro_1235 transporter-like protein; PFAM: Uncharacterised conserved protein UCP037409, membrane transporter, MTH672; SPTR: transporter-like protein; PFAM: Predicted transporter (DUF2162) YP_004369416.1 COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: ppd:Ppro_1234 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family YP_004369417.1 COGs: COG4744 conserved hypothetical protein; InterPro IPR018676; KEGG: ppd:Ppro_1233 hypothetical protein; PFAM: protein of unknown function DUF2149; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2149) YP_004369418.1 COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003672; KEGG: glo:Glov_3671 cobaltochelatase; PFAM: CobN/magnesium chelatase; PRIAM: Magnesium chelatase; SPTR: Cobaltochelatase; PFAM: CobN/Magnesium Chelatase YP_004369419.1 COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: afw:Anae109_0170 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: uncharacterized protein; PFAM: MotA/TolQ/ExbB proton channel family YP_004369420.1 COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: bba:Bd0478 TonB system transport protein ExbD2; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: uncharacterized protein; PFAM: Biopolymer transport protein ExbD/TolR YP_004369421.1 COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260; KEGG: alv:Alvin_2252 TonB family protein; PFAM: TonB, C-terminal; SPTR: TonB family protein; TIGRFAM: TonB, C-terminal; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain YP_004369422.1 COGs: COG1348 nitrogenase subunit NifH (ATPase); HAMAP: nitrogenase iron protein NifH; InterPro IPR005977:IPR000392; KEGG: sfu:Sfum_1019 nitrogenase reductase; PFAM: nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL; PRIAM: nitrogenase; SPTR: nitrogenase iron protein; TIGRFAM: nitrogenase iron protein NifH; PFAM: 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family; TIGRFAM: nitrogenase iron protein YP_004369423.1 COGs: COG0347 nitrogen regulatory protein PII; InterPro IPR002187; KEGG: sfu:Sfum_1018 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein PII; SMART: nitrogen regulatory protein PII; SPTR: nitrogen fixation nifHD1 region glnB-like protein 1; PFAM: nitrogen regulatory protein P-II YP_004369424.1 COGs: COG0347 nitrogen regulatory protein PII; InterPro IPR002187; KEGG: sfu:Sfum_1017 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein PII; SMART: nitrogen regulatory protein PII; SPTR: nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II YP_004369425.1 COGs: COG2710 nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR005972:IPR010143:IPR000510; KEGG: sfu:Sfum_1016 nitrogenase molybdenum-iron protein alpha chain; PFAM: nitrogenase/oxidoreductase, component 1; SPTR: nitrogenase alpha chain; TIGRFAM: nitrogenase molybdenum-iron protein alpha chain; nitrogenase component 1, alpha chain; PFAM: nitrogenase component 1 type Oxidoreductase; TIGRFAM: nitrogenase component I, alpha chain; nitrogenase molybdenum-iron protein alpha chain YP_004369426.1 COGs: COG2710 nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR005976:IPR000510; KEGG: sfu:Sfum_1015 nitrogenase molybdenum-iron protein beta chain; PFAM: nitrogenase/oxidoreductase, component 1; SPTR: nitrogenase molybdenum-iron protein beta chain; TIGRFAM: nitrogenase molybdenum-iron protein beta chain; PFAM: nitrogenase component 1 type Oxidoreductase; TIGRFAM: nitrogenase molybdenum-iron protein beta chain YP_004369427.1 KEGG: dvl:Dvul_3095 ferredoxin, 2fe-2s; SPTR: Ferredoxin, 2fe-2s YP_004369428.1 COGs: COG2710 nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR005973:IPR000510; KEGG: sfu:Sfum_1013 nitrogenase MoFe cofactor biosynthesis protein NifE; PFAM: nitrogenase/oxidoreductase, component 1; SPTR: nitrogenase MoFe cofactor biosynthesis protein NifE; TIGRFAM: nitrogenase MoFe cofactor biosynthesis protein NifE; PFAM: nitrogenase component 1 type Oxidoreductase; TIGRFAM: nitrogenase molybdenum-iron cofactor biosynthesis protein NifE YP_004369429.1 COGs: COG2710 nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR000510; KEGG: sfu:Sfum_1012 nitrogenase; PFAM: nitrogenase/oxidoreductase, component 1; PRIAM: nitrogenase; SPTR: uncharacterized protein; PFAM: nitrogenase component 1 type Oxidoreductase YP_004369430.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR006638:IPR005980:IPR007197:IPR003731; KEGG: sfu:Sfum_1011 nitrogenase cofactor biosynthesis protein NifB; PFAM: Radical SAM; Dinitrogenase iron-molybdenum cofactor biosynthesis; SMART: Elongator protein 3/MiaB/NifB; SPTR: nitrogenase cofactor biosynthesis protein NifB; TIGRFAM: nitrogenase cofactor biosynthesis protein NifB; PFAM: Radical SAM superfamily; Dinitrogenase iron-molybdenum cofactor; TIGRFAM: nitrogenase cofactor biosynthesis protein NifB YP_004369431.1 COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: tye:THEYE_A1623 ABC transporter; PFAM: ABC transporter; SPTR: ABC transporter; PFAM: ABC transporter YP_004369432.1 COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: tye:THEYE_A1624 ATPase component ABC-type multidrug transport system; PFAM: ABC transporter; SPTR: ATPase component ABC-type multidrug transport system; PFAM: ABC transporter YP_004369433.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: tye:THEYE_A1627 ABC transporter ATP-binding component; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter ATP-binding component; PFAM: ABC transporter YP_004369434.1 COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: tye:THEYE_A1628 HlyD family secretion protein, PFAM: Secretion protein HlyD; SPTR: HlyD family secretion protein, ; PFAM: HlyD family secretion protein YP_004369435.1 COGs: COG0778 nitroreductase; InterPro IPR020051:IPR000415; KEGG: dau:Daud_0678 nitroreductase; PFAM: nitroreductase-like; SPTR: uncharacterized protein; TIGRFAM: SagB-type dehydrogenase domain; PFAM: nitroreductase; TIGRFAM: SagB-type dehydrogenase domain YP_004369436.1 COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; HAMAP: 5-methylthioadenosine/S-adenosylhomocysteine deaminase; InterPro IPR006680; KEGG: sfu:Sfum_2961 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: 5-methylthioadenosine/S-adenosylhomocysteine deaminase; PFAM: Amidohydrolase YP_004369437.1 InterPro IPR008258; KEGG: sfu:Sfum_0486 lytic transglycosylase, catalytic; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Lytic transglycosylase, catalytic; PFAM: transglycosylase SLT domain YP_004369438.1 COGs: COG1569 nucleic acid-binding protein contains PIN domain; InterPro IPR002850; KEGG: gur:Gura_1139 nucleotide binding protein, PINc; SPTR: nucleotide binding protein, PINc; TIGRFAM: protein of unknown function DUF132; TIGRFAM: toxin-antitoxin system toxin component, PIN family YP_004369439.1 InterPro IPR007159:IPR006339; KEGG: sfu:Sfum_0409 AbrB family transcriptional regulator; SMART: transcription regulator AbrB/SpoV, predicted; SPTR: AbrB family transcriptional regulator; TIGRFAM: transcription regulator AbrB; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family YP_004369440.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: dal:Dalk_2812 glycosyl transferase 2; PFAM: glycosyl transferase, family 2; SPTR: glycosyl transferase 2; PFAM: glycosyl transferase 2 YP_004369441.1 COGs: COG1410 methionine synthase I cobalamin-binding domain; InterPro IPR000489; KEGG: dol:Dole_2576 dihydropteroate synthase DhpS; PFAM: Pterin-binding; SPTR: dihydropteroate synthase DHPS; PFAM: Pterin binding enzyme YP_004369442.1 COGs: COG0778 nitroreductase; InterPro IPR000415; KEGG: mta:Moth_1834 nitroreductase; PFAM: nitroreductase-like; SPTR: nitroreductase; PFAM: nitroreductase YP_004369443.1 COGs: COG0162 Tyrosyl-tRNA synthetase; HAMAP: Tyrosyl-tRNA synthetase, class Ib; InterPro IPR002942:IPR002307:IPR002305; KEGG: geo:Geob_3588 tyrosyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ib; RNA-binding S4; PRIAM: Tyrosine--tRNA ligase; SMART: RNA-binding S4; SPTR: Tyrosyl-tRNA synthetase; TIGRFAM: Tyrosyl-tRNA synthetase, class Ib; PFAM: S4 domain; tRNA synthetases class I (W and Y); TIGRFAM: tyrosyl-tRNA synthetase YP_004369444.1 COGs: COG4395 conserved hypothetical protein; InterPro IPR007379; KEGG: gsu:GSU1091 lipoprotein; PFAM: Membrane transporter, Tim44-related/ribosomal protein L45; SMART: Membrane transporter, Tim44-related/ribosomal protein L45; SPTR: transport protein, Tim44-like domain, ; PFAM: Tim44-like domain YP_004369445.1 COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR000644:IPR001667:IPR003156:IPR002646; KEGG: sfu:Sfum_0679 polynucleotide adenylyltransferase region; PFAM: cystathionine beta-synthase, core; phosphoesterase, RecJ-like; phosphoesterase, DHHA1; poly A polymerase, head domain; SPTR: polynucleotide adenylyltransferase region; PFAM: DHH family; DHHA1 domain; CBS domain; poly A polymerase head domain YP_004369446.1 COGs: COG4974 Site-specific recombinase XerD; HAMAP: Tyrosine recombinase xerC; Tyrosine recombinase XerD; InterPro IPR011932:IPR004107:IPR002104; KEGG: bts:Btus_1324 tyrosine recombinase XerD; PFAM: Integrase, catalytic core, phage; Integrase, N-terminal SAM-like, phage; SPTR: Tyrosine recombinase XerD; TIGRFAM: Tyrosine recombinase XerD; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase; TIGRFAM: tyrosine recombinase XerD YP_004369447.1 COGs: COG0254 ribosomal protein L31; HAMAP: ribosomal protein L31; InterPro IPR002150; KEGG: sfu:Sfum_1712 ribosomal protein L31; PFAM: ribosomal protein L31; SPTR: 50S ribosomal protein L31; TIGRFAM: ribosomal protein L31; PFAM: ribosomal protein L31; TIGRFAM: ribosomal protein L31 YP_004369448.1 COGs: COG3872 metal-dependent protein; InterPro IPR010787; KEGG: dbr:Deba_0736 protein of unknown function DUF1385; PFAM: protein of unknown function DUF1385; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1385) YP_004369449.1 COGs: COG0216 protein chain release factor A; HAMAP: peptide chain release factor 1; InterPro IPR005139:IPR004373:IPR000352; KEGG: dsa:Desal_2606 peptide chain release factor 1; PFAM: peptide chain release factor class I/class II; peptide chain release factor; SMART: peptide chain release factor; SPTR: peptide chain release factor 1; TIGRFAM: peptide chain release factor 1; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 1 YP_004369450.1 COGs: COG2890 methylase of polypeptide chain release factors; InterPro IPR004556:IPR019874:IPR007848; KEGG: sfu:Sfum_1714 HemK family modification methylase; PFAM: methyltransferase small; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Modification methylase, HemK family; TIGRFAM: protein-(glutamine-N5) methyltransferase, release factor-specific; Modification methylase HemK; PFAM: methyltransferase small domain; TIGRFAM: HemK family methylases; protein-(glutamine-N5) methyltransferase, release factor-specific YP_004369451.1 COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: sfu:Sfum_0851 phosphoesterase domain-containing protein; PFAM: phosphoesterase, RecJ-like; phosphoesterase, DHHA1; SPTR: uncharacterized protein; PFAM: DHHA1 domain; DHH family YP_004369452.1 COGs: COG0436 aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: dak:DaAHT2_0099 aminotransferase class I and II; PFAM: Aminotransferase, class I/classII; PRIAM: aspartate transaminase; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II YP_004369453.1 COGs: COG0622 phosphoesterase; InterPro IPR000979:IPR004843; KEGG: tna:CTN_0812 phosphodiesterase, MJ0936 family; PFAM: Metallo-dependent phosphatase; SPTR: phosphodiesterase, MJ0936 family; TIGRFAM: phosphodiesterase MJ0936; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family YP_004369454.1 KEGG: gbm:Gbem_0481 hypothetical protein; SPTR: uncharacterized protein YP_004369455.1 COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013217; KEGG: mpo:Mpop_1471 methyltransferase type 11; PFAM: methyltransferase type 12; SPTR: methyltransferase type 11; PFAM: methyltransferase domain YP_004369456.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR006158:IPR007197; KEGG: gur:Gura_0376 radical SAM domain-containing protein; PFAM: Radical SAM; Cobalamin (vitamin B12)-binding; SMART: Elongator protein 3/MiaB/NifB; SPTR: radical SAM protein; PFAM: Radical SAM superfamily; B12 binding domain YP_004369457.1 COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: sfu:Sfum_1059 hypothetical protein; PFAM: Domain of unknown function DUF39; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF39 YP_004369458.1 COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232:IPR018317; KEGG: chy:CHY_1281 hypothetical protein; PFAM: Queuosine synthesis; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00268; PFAM: ExsB; TIGRFAM: TIGR00268 family protein YP_004369459.1 COGs: COG2206 HD-GYP domain; InterPro IPR003018:IPR003607:IPR006674; KEGG: dal:Dalk_4245 metal dependent phosphohydrolase; PFAM: GAF; Metal-dependent phosphohydrolase, HD subdomain; SMART: GAF; Metal-dependent phosphohydrolase, HD domain; SPTR: Metal dependent phosphohydrolase; PFAM: HD domain; GAF domain YP_004369460.1 COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; InterPro IPR020536:IPR008532; KEGG: dat:HRM2_31040 tRNA, (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: Domain of unknown function DUF814; Thiamine biosynthesis protein, C-terminal; SPTR: tRNA, (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: Domain of unknown function (DUF814); Thiamine biosynthesis protein (ThiI) YP_004369461.1 COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: dba:Dbac_0668 O-methyltransferase 3; PFAM: O-methyltransferase, family 3; SPTR: O-methyltransferase 3; PFAM: O-methyltransferase YP_004369462.1 COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; InterPro IPR015168; KEGG: sfu:Sfum_2205 ABC transporter substrate-binding protein; SPTR: ABC transporter substrate-binding protein; PFAM: NMT1/THI5 like YP_004369463.1 COGs: COG2114 adenylate cyclase 3 (some protein contain HAMP domain); InterPro IPR003660:IPR001054:IPR004010; KEGG: sfu:Sfum_2204 serine phosphatase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; Cache; HAMP linker domain; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; HAMP linker domain; SPTR: Serine phosphatase; PFAM: adenylate and Guanylate cyclase catalytic domain; HAMP domain; Cache domain YP_004369464.1 InterPro IPR013740; KEGG: sat:SYN_00592 hypothetical protein; PFAM: Redoxin; SPTR: Antioxidant, AhpC/TSA family; PFAM: Redoxin YP_004369465.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: cpc:Cpar_0883 UspA domain protein; PFAM: UspA; SPTR: UspA domain protein; PFAM: Universal stress protein family YP_004369466.1 COGs: COG1522 transcriptional regulators; InterPro IPR019888; KEGG: dol:Dole_0464 AsnC family transcriptional regulator; SMART: transcription regulator AsnC-type; SPTR: AsnC family transcriptional regulator YP_004369467.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR006638:IPR007197; KEGG: sfu:Sfum_3058 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: radical SAM protein; PFAM: Radical SAM superfamily; TIGRFAM: heme d1 biosynthesis radical SAM protein NirJ2; radical SAM additional 4Fe4S-binding domain YP_004369468.1 COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: sfu:Sfum_3057 delta-aminolevulinic acid dehydratase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; PRIAM: porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase YP_004369469.1 COGs: COG3405 Endoglucanase Y; InterPro IPR002037; KEGG: plt:Plut_0993 cellulase; PFAM: glycoside hydrolase, family 8; SPTR: Cellulase; PFAM: glycosyl hydrolases family 8 YP_004369470.1 COGs: COG3272 conserved hypothetical protein; InterPro IPR007553:IPR013560; KEGG: drt:Dret_1323 protein of unknown function DUF523; PFAM: Domain of unknown function DUF523; Domain of unknown function DUF1722; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF523); protein of unknown function (DUF1722) YP_004369471.1 COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: dol:Dole_0174 peptidylprolyl isomerase FKBP-type; PFAM: peptidyl-prolyl cis-trans isomerase, FKBP-type; SPTR: uncharacterized protein; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase YP_004369472.1 COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR003385; KEGG: nde:NIDE1254 4-alpha-glucanotransferase; PFAM: glycoside hydrolase, family 77; PRIAM: 4-alpha-glucanotransferase; SPTR: 4-alpha-glucanotransferase; TIGRFAM: glycoside hydrolase, family 77; PFAM: 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase YP_004369473.1 COGs: COG0366 glycosidase; InterPro IPR006589:IPR006047; KEGG: nhl:Nhal_2846 alpha amylase catalytic region; PFAM: glycosyl hydrolase, family 13, catalytic domain; SMART: glycosyl hydrolase, family 13, subfamily, catalytic domain; SPTR: Alpha amylase, catalytic domain subfamily, ; PFAM: Alpha amylase, catalytic domain YP_004369474.1 COGs: COG1720 conserved hypothetical protein; InterPro IPR001378; KEGG: mem:Memar_0464 hypothetical protein; PFAM: Uncharacterised protein family UPF0066; SPTR: uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0066; PFAM: Uncharacterised protein family UPF0066; TIGRFAM: methyltransferase, YaeB/AF_0241 family YP_004369475.1 COGs: COG0181 porphobilinogen deaminase; HAMAP: Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; InterPro IPR000860:IPR022417:IPR022418; KEGG: glo:Glov_0502 porphobilinogen deaminase; PFAM: porphobilinogen deaminase, N-terminal; porphobilinogen deaminase, C-terminal domain; SPTR: porphobilinogen deaminase; TIGRFAM: Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; PFAM: porphobilinogen deaminase, C-terminal domain; porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase YP_004369476.1 COGs: COG3894 Uncharacterized metal-binding protein; InterPro IPR001041; KEGG: sfu:Sfum_1991 ferredoxin; PFAM: Ferredoxin; SPTR: Ferredoxin; PFAM: 2Fe-2S iron-sulfur cluster binding domain YP_004369477.1 COGs: COG0531 Amino acid transporter; InterPro IPR004841; KEGG: cte:CT0923 amino acid permease; PFAM: Amino acid permease domain; SPTR: Amino acid permease; PFAM: Amino acid permease YP_004369478.1 KEGG: ptm:GSPATT00039468001 hypothetical protein; SPTR: uncharacterized protein YP_004369479.1 COGs: COG1657 Squalene cyclase; InterPro IPR006400:IPR018333:IPR001330; KEGG: gme:Gmet_2820 terpene synthase:squalene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Terpene synthase:Squalene cyclase; TIGRFAM: Hopene cyclase; Squalene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase YP_004369480.1 COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR020842:IPR017829:IPR001509; KEGG: gem:GM21_0884 hopanoid-associated sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase; SMART: polyketide synthase/Fatty acid synthase, KR; SPTR: Hopanoid-associated sugar epimerase; TIGRFAM: Hopanoid-associated sugar epimerase; PFAM: NAD dependent epimerase/dehydratase; TIGRFAM: hopanoid-associated sugar epimerase YP_004369481.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR006638:IPR017833:IPR007197; KEGG: gur:Gura_1017 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: radical SAM protein; TIGRFAM: Hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM superfamily; Domain of unknown function (DUF3463); TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH YP_004369482.1 COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR000184; KEGG: gsu:GSU0368 lipoprotein; PFAM: Bacterial surface antigen (D15); SPTR: Lipoprotein, ; PFAM: Surface antigen YP_004369483.1 COGs: COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family; InterPro IPR003342; KEGG: gur:Gura_3694 glycosyl transferase; PFAM: glycosyl transferase, family 39; SPTR: glycosyl transferase 39; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase YP_004369484.1 COGs: COG0705 membrane protein; InterPro IPR022764; KEGG: dal:Dalk_3454 rhomboid family protein; PFAM: peptidase S54, rhomboid domain; SPTR: Rhomboid family protein; PFAM: Rhomboid family YP_004369485.1 COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); HAMAP: Trigger factor; InterPro IPR005215:IPR008881:IPR001179:IPR008880; KEGG: dbr:Deba_1454 trigger factor; PFAM: Trigger factor, C-terminal, bacterial; Trigger factor, ribosome-binding, bacterial; peptidyl-prolyl cis-trans isomerase, FKBP-type; SPTR: Trigger factor; TIGRFAM: Trigger factor; PFAM: Bacterial trigger factor protein (TF) C-terminus; Bacterial trigger factor protein (TF); TIGRFAM: trigger factor YP_004369486.1 COGs: COG0740 Protease subunit of ATP-dependent Clp protease; HAMAP: peptidase S14, ClpP; InterPro IPR001907; KEGG: sfu:Sfum_0100 ATP-dependent Clp protease, proteolytic subunit ClpP; PFAM: peptidase S14, ClpP; PRIAM: Endopeptidase Clp; SPTR: ATP-dependent Clp protease proteolytic subunit; TIGRFAM: peptidase S14, ClpP; PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP YP_004369487.1 COGs: COG1219 ATP-dependent protease Clp ATPase subunit; HAMAP: Clp protease, ATP-binding subunit ClpX; InterProIPR003593:IPR004487:IPR010603:IPR013093:IPR 019489; KEGG: dbr:Deba_1456 ATP-dependent Clp protease, ATP-binding subunit ClpX; PFAM: ATPase, AAA-2; Zinc finger, C4-type; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent Clp protease, ATP-binding subunit ClpX; TIGRFAM: Clp protease, ATP-binding subunit ClpX; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ClpX C4-type zinc finger; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX) YP_004369488.1 COGs: COG0466 ATP-dependent Lon protease; InterProIPR003111:IPR003593:IPR004815:IPR003959:IPR 008269; KEGG: sfu:Sfum_0098 ATP-dependent protease La; PFAM: peptidase S16, Lon C-terminal; peptidase S16, lon N-terminal; ATPase, AAA-type, core; PRIAM: Endopeptidase La; SMART: peptidase S16, lon N-terminal; ATPase, AAA+ type, core; SPTR: ATP-dependent protease La; TIGRFAM: peptidase S16, ATP-dependent protease La; PFAM: ATP-dependent protease La (LON) domain; ATPase associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La YP_004369489.1 COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: dak:DaAHT2_2164 transcriptional regulator; PFAM: ATPase, AAA-4; SPTR: transcriptional regulator; PFAM: Divergent AAA domain YP_004369490.1 COGs: COG2944 transcriptional regulator protein; KEGG: plt:Plut_0850 XRE family transcriptional regulator; SPTR: XRE family transcriptional regulator YP_004369491.1 COGs: COG2929 conserved hypothetical protein; InterPro IPR007460; KEGG: cyh:Cyan8802_3951 protein of unknown function DUF497; PFAM: protein of unknown function DUF497; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF497) YP_004369492.1 KEGG: cyc:PCC7424_5049 hypothetical protein; SPTR: uncharacterized protein YP_004369493.1 InterPro IPR002145; KEGG: mrb:Mrub_1622 CopG domain-containing protein DNA-binding domain-containing protein; PFAM: CopG-like DNA-binding; SPTR: CopG domain protein DNA-binding domain protein; PFAM: Ribbon-helix-helix protein, copG family YP_004369494.1 KEGG: dau:Daud_0415 twitching mobility protein PilT; SPTR: twitching mobility protein PilT YP_004369495.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003018:IPR000014:IPR003661:IPR003594:IPR 001789:IPR013767; KEGG: sfu:Sfum_2401 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; GAF; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; GAF; PAS; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SPTR: Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: GAF domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004369496.1 KEGG: sfu:Sfum_1591 hypothetical protein; SPTR: uncharacterized protein YP_004369497.1 KEGG: kfl:Kfla_5531 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranosidedeacetyla se YP_004369498.1 COGs: COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division; HAMAP: glucose-inhibited division protein A; InterPro IPR004416:IPR002218; KEGG: sat:SYN_01650 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; PFAM: glucose-inhibited division protein A-related; SPTR: tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; TIGRFAM: glucose-inhibited division protein A; PFAM: glucose inhibited division protein A; TIGRFAM: glucose-inhibited division protein A YP_004369499.1 KEGG: pno:SNOG_12402 hypothetical protein YP_004369500.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: npu:Npun_F3046 UspA domain-containing protein; PFAM: UspA; SPTR: UspA domain protein; PFAM: Universal stress protein family YP_004369501.1 KEGG: ton:TON_0783 cationic amino acid transporter (cat-1); SPTR: Cationic amino acid transporter (Cat-1); PFAM: Universal stress protein family YP_004369502.1 KEGG: dds:Ddes_1205 cell divisionFtsK/SpoIIIE; SPTR: Cell divisionFtsK/SpoIIIE YP_004369503.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dvm:DvMF_0706 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain YP_004369504.1 COGs: COG0574 phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279; KEGG: dvm:DvMF_0705 pyruvate, water dikinase; PFAM: pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile domain; PRIAM: pyruvate, water dikinase; SPTR: pyruvate, water dikinase; PFAM: PEP-utilising enzyme, mobile domain; pyruvate phosphate dikinase, PEP/pyruvate binding domain YP_004369505.1 InterPro IPR019088; KEGG: dvm:DvMF_0704 hypothetical protein; PFAM: Conserved hypothetical protein CHP02186-related, transmembrane; SPTR: uncharacterized protein; PFAM: transmembrane protein (Alph_Pro_TM) YP_004369506.1 COGs: COG0730 permease; InterPro IPR002781; KEGG: dvm:DvMF_0703 protein of unknown function DUF81; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004369507.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: dvm:DvMF_0700 two component, sigma54 specific, transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004369508.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: dvm:DvMF_0701 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: uncharacterized protein; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004369509.1 COGs: COG0515 Serine/threonine protein kinase; InterProIPR001789:IPR000014:IPR002290:IPR020635:IPR 013767:IPR017442; KEGG: dat:HRM2_10160 Spk; PFAM: Serine/threonine-protein kinase-like domain; Signal transduction response regulator, receiver domain; PAS fold; PRIAM: Calcium/calmodulin-dependent protein kinase; SMART: Serine/threonine-protein kinase domain; Signal transduction response regulator, receiver domain; PAS; Tyrosine-protein kinase, catalytic domain; SPTR: Spk; TIGRFAM: PAS; PFAM: protein kinase domain; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box YP_004369510.1 COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003593:IPR010066:IPR003439:IPR013563; KEGG: mxa:MXAN_4664 oligopeptide/dipeptide ABC transporter ATP-binding protein; PFAM: ABC transporter-like; Oligopeptide/dipeptide ABC transporter, C-terminal; PRIAM: nickel ABC transporter ATPase; SMART: ATPase, AAA+ type, core; SPTR: Oligopeptide/dipeptide ABC transporter; TIGRFAM: Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004369511.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003593:IPR010066:IPR003439:IPR013563; KEGG: bbe:BBR47_15580 ABC transporter ATP binding protein; PFAM: ABC transporter-like; Oligopeptide/dipeptide ABC transporter, C-terminal; PRIAM: nickel ABC transporter ATPase; SMART: ATPase, AAA+ type, core; SPTR: Oligopeptide transport ATP-binding protein AppD; TIGRFAM: Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004369512.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR000014:IPR003661:IPR003594:IPR013767; KEGG: sfu:Sfum_2495 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; SPTR: PAS domain S-box protein; TIGRFAM: PAS; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004369513.1 COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR020841:IPR017568:IPR014030:IPR014031; KEGG: tye:THEYE_A0103 beta-ketoacyl-acyl carrier protein synthase II; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase II; SMART: polyketide synthase, beta-ketoacyl synthase domain; SPTR: Beta-ketoacyl-acyl carrier protein synthase II; TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: beta-ketoacyl-acyl-carrier-protein synthase II YP_004369514.1 KEGG: dol:Dole_2148 hypothetical protein; SPTR: uncharacterized protein YP_004369515.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: nde:NIDE0511 phosphatidylethanolamine N-methyltransferase; PFAM: methyltransferase type 11; SPTR: Similar to phosphatidylethanolamine N-methyltransferase; PFAM: methyltransferase domain YP_004369516.1 COGs: COG0318 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: gmc:GY4MC1_0877 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Long-chain-fatty-acid--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme YP_004369517.1 KEGG: ote:Oter_1511 hypothetical protein; SPTR: uncharacterized protein YP_004369518.1 KEGG: cpi:Cpin_4616 transcriptional regulator, HxlR family; SPTR: transcriptional regulator, HxlR family YP_004369519.1 COGs: COG0611 Thiamine monophosphate kinase; InterPro IPR006283:IPR000728:IPR010918; KEGG: dak:DaAHT2_1499 thiamine-monophosphate kinase; PFAM: AIR synthase-related protein; AIR synthase-related protein, C-terminal; PRIAM: Thiamine-phosphate kinase; SPTR: Thiamine-monophosphate kinase; TIGRFAM: Thiamine-monophosphate kinase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: thiamine-monophosphate kinase YP_004369520.1 COGs: COG0105 nucleoside diphosphate kinase; HAMAP: nucleoside diphosphate kinase; InterPro IPR001564; KEGG: dol:Dole_2625 nucleoside-diphosphate kinase; PFAM: nucleoside diphosphate kinase; PRIAM: nucleoside-diphosphate kinase; SMART: nucleoside diphosphate kinase; SPTR: nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase YP_004369521.1 COGs: COG0480 translation elongation factors (GTPase); InterProIPR005517:IPR000640:IPR004540:IPR005225:IPR 000795:IPR004161; KEGG: dbr:Deba_2408 translation elongation factor G; PFAM: protein synthesis factor, GTP-binding; translation elongation factor EFTu/EF1A, domain 2; translation elongation factor EFG/EF2, domain IV; translation elongation factor EFG/EF2, C-terminal; SMART: translation elongation factor EFG/EF2, C-terminal; translation elongation factor EFG/EF2, domain IV; SPTR: Elongation factor G 1; TIGRFAM: translation elongation factor EFG/EF2; Small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain YP_004369522.1 COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017; KEGG: sfu:Sfum_2146 hypothetical protein; PFAM: cysteine-rich domain; SPTR: uncharacterized protein; PFAM: cysteine-rich domain YP_004369523.1 KEGG: dat:HRM2_39100 hypothetical protein; SPTR: uncharacterized protein YP_004369524.1 COGs: COG0063 sugar kinase; KEGG: dat:HRM2_44810 hypothetical protein; SPTR: uncharacterized protein; PFAM: Carbohydrate kinase YP_004369525.1 KEGG: dol:Dole_3247 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3343) YP_004369526.1 InterPro IPR001455; KEGG: dbr:Deba_0011 SirA family protein; PFAM: SirA-like; SPTR: SirA family protein; PFAM: SirA-like protein YP_004369527.1 KEGG: pca:Pcar_0820 hypothetical protein; SPTR: uncharacterized protein; PFAM: YeeE/YedE family (DUF395) YP_004369528.1 COGs: COG0709 Selenophosphate synthase; HAMAP: Selenide, water dikinase, class I; InterPro IPR004536:IPR023061:IPR000728:IPR010918; KEGG: sfu:Sfum_3401 selenide, water dikinase; PFAM: AIR synthase-related protein; AIR synthase-related protein, C-terminal; SPTR: Selenophosphate synthase; TIGRFAM: Selenide water dikinase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: selenium donor protein YP_004369529.1 KEGG: nmu:Nmul_A0965 hypothetical protein; SPTR: uncharacterized protein YP_004369530.1 COGs: COG1402 Uncharacterized protein amidase; InterPro IPR003785; KEGG: ppd:Ppro_1784 creatininase; PFAM: Creatininase; SPTR: amidase; PFAM: Creatinine amidohydrolase YP_004369531.1 KEGG: sat:SYN_03569 cytoplasmic protein; SPTR: Hypothetical cytosolic protein YP_004369532.1 COGs: COG1160 GTPase; HAMAP: GTP-binding, EngA; InterPro IPR005225:IPR016484:IPR002917; KEGG: dak:DaAHT2_0855 ribosome-associated GTPase EngA; PFAM: GTP-binding protein, HSR1-related; SPTR: ribosome-associated GTPase EngA; TIGRFAM: GTP-binding, EngA; Small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein domain YP_004369533.1 COGs: COG0793 Periplasmic protease; InterPro IPR001478:IPR005151:IPR004447; KEGG: ppd:Ppro_2409 carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF; SMART: peptidase S41; PDZ/DHR/GLGF; SPTR: Carboxyl-terminal protease; TIGRFAM: peptidase S41A, C-terminal peptidase; PFAM: peptidase S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc) YP_004369534.1 COGs: COG0793 Periplasmic protease; InterPro IPR001478:IPR005151:IPR004447; KEGG: dbr:Deba_1769 carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF; PRIAM: C-terminal processing peptidase; SMART: peptidase S41; PDZ/DHR/GLGF; SPTR: Carboxyl-terminal protease; TIGRFAM: peptidase S41A, C-terminal peptidase; PFAM: peptidase S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc) YP_004369535.1 COGs: COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit; HAMAP: Glu-tRNAGln amidotransferase, C subunit; InterPro IPR003837; KEGG: gbm:Gbem_3643 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; PFAM: Glu-tRNAGln amidotransferase, C subunit; SPTR: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; TIGRFAM: Glu-tRNAGln amidotransferase, C subunit; PFAM: Glu-tRNAGln amidotransferase C subunit; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit YP_004369536.1 COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; HAMAP: glutamyl-tRNA(Gln) amidotransferase A subunit; InterPro IPR004412:IPR000120; KEGG: gsu:GSU3381 aspartyl/glutamyl-tRNA amidotransferase subunit A; PFAM: Amidase; PRIAM: Amidase; SPTR: glutamyl-tRNA(Gln) amidotransferase subunit A; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase A subunit; PFAM: Amidase; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit YP_004369537.1 COGs: COG1968 Uncharacterized bacitracin resistance protein; HAMAP: Bacitracin resistance protein BacA; InterPro IPR003824; KEGG: pth:PTH_1292 hypothetical protein; PFAM: Bacitracin resistance protein BacA; SPTR: Undecaprenyl-diphosphatase; TIGRFAM: Bacitracin resistance protein BacA; PFAM: Bacitracin resistance protein BacA; TIGRFAM: undecaprenyl-diphosphatase UppP YP_004369539.1 COGs: COG0767 ABC-type transport system involved in resistance to organic solvents permease component; InterPro IPR003453; KEGG: drt:Dret_0676 protein of unknown function DUF140; PFAM: Domain of unknown function DUF140; SPTR: uncharacterized protein; TIGRFAM: Domain of unknown function DUF140; manually curated; PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein YP_004369540.1 COGs: COG1127 ABC-type transport system involved in resistance to organic solvents ATPase component; InterPro IPR003593:IPR003439; KEGG: dbr:Deba_0203 ABC transporter; PFAM: ABC transporter-like; PRIAM: iron ABC transporter ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter; PFAM: ABC transporter YP_004369541.1 COGs: COG0368 Cobalamin-5-phosphate synthase; HAMAP: Cobalamin (vitamin B12) biosynthesis CobS, cobalamin-5-phosphate synthase; InterPro IPR003805; KEGG: sfu:Sfum_2609 cobalamin 5'-phosphate synthase; PFAM: Cobalamin (vitamin B12) biosynthesis CobS, cobalamin-5-phosphate synthase; SPTR: Cobalamin synthase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobS, cobalamin-5-phosphate synthase; PFAM: Cobalamin-5-phosphate synthase; TIGRFAM: cobalamin 5'-phosphate synthase/cobalamin synthase YP_004369542.1 COGs: COG2038 NaMN:DMB phosphoribosyltransferase; HAMAP: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic; InterPro IPR017846:IPR003200; KEGG: nde:NIDE2664 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like; PRIAM: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; SPTR: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; TIGRFAM:Nicotinate-nucleotide- dimethylbenzimidazole phosphoribosyltransferase, prokaryotic; PFAM: phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_004369543.1 COGs: COG2087 adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: dvl:Dvul_1982 cobalbumin biosynthesis enzyme; PFAM: Cobinamide kinase/cobinamide phosphate guanyltransferase; PRIAM: adenosylcobinamide-phosphate guanylyltransferase; SPTR: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase YP_004369544.1 COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: slp:Slip_0757 cob(I)alamin adenosyltransferase; PFAM: adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: Cob(I)alamin adenosyltransferase; TIGRFAM: adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase YP_004369545.1 KEGG: npu:Npun_F1563 major facilitator transporter; SPTR: Major facilitator superfamily transporter permease YP_004369546.1 InterPro IPR013525; KEGG: tye:THEYE_A1645 ABC transporter superfamily; PFAM: ABC transporter; SPTR: ABC transporter superfamily; PFAM: ABC transporter YP_004369547.1 COGs: COG0347 nitrogen regulatory protein PII; InterPro IPR002187; KEGG: pca:Pcar_1500 regulatory protein P-II for glutamine synthetase; PFAM: nitrogen regulatory protein PII; SMART: nitrogen regulatory protein PII; SPTR: nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II YP_004369548.1 COGs: COG1703 periplasmic protein kinase ArgK and related GTPase of G3E family; InterPro IPR003593:IPR005129; KEGG: gme:Gmet_1576 ArgK protein; PFAM: ArgK protein; SMART: ATPase, AAA+ type, core; SPTR: LAO/AO transport system ATPase; TIGRFAM: ArgK protein; PFAM: ArgK protein; TIGRFAM: LAO/AO transport system ATPase YP_004369549.1 COGs: COG0652 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130; KEGG: dma:DMR_18750 peptidyl-prolyl cis-trans isomerase B; PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PRIAM: peptidylprolyl isomerase; SPTR: peptidyl-prolyl cis-trans isomerase; PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YP_004369550.1 COGs: COG1530 ribonuclease G and E; InterPro IPR022967:IPR004659:IPR003029:IPR019307; KEGG: gur:Gura_1256 ribonuclease; PFAM: RNA-binding protein AU-1/ribonuclease E/G; ribosomal protein S1, RNA-binding domain; SMART: RNA-binding domain, S1; SPTR: ribonuclease E; TIGRFAM: ribonuclease E/G; PFAM: ribonuclease E/G family; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family YP_004369551.1 COGs: COG0129 dihydroxyacid dehydratase/phosphogluconate dehydratase; HAMAP: dihydroxy-acid dehydratase; InterPro IPR004404:IPR000581; KEGG: sat:SYN_01708 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid/6-phosphogluconate dehydratase; PRIAM: dihydroxy-acid dehydratase; SPTR: dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase; TIGRFAM: dihydroxy-acid dehydratase YP_004369552.1 COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001:IPR022634:IPR022637:IPR022635; KEGG: geo:Geob_0002 DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain, N-terminal; DNA polymerase III, beta chain, central; DNA polymerase III, beta chain, C-terminal; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III, beta chain; SPTR: DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta chain; PFAM: DNA polymerase III beta subunit, C-terminal domain; DNA polymerase III beta subunit, N-terminal domain; DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit YP_004369553.1 COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterProIPR003594:IPR001241:IPR011557:IPR013506:IPR 006171:IPR002288; KEGG: sfu:Sfum_2689 DNA gyrase, B subunit; PFAM: DNA topoisomerase, type IIA, subunit B, domain 2; ATPase-like, ATP-binding domain; Toprim domain; DNA topoisomerase, type IIA, subunit B, C-terminal; SMART: DNA topoisomerase, type IIA, subunit B/N-terminal; ATPase-like, ATP-binding domain; SPTR: DNA gyrase subunit B; TIGRFAM: DNA gyrase, subunit B; PFAM: Toprim domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus; TIGRFAM: DNA gyrase, B subunit YP_004369554.1 KEGG: sfu:Sfum_1747 hypothetical protein; SPTR: uncharacterized protein YP_004369555.1 KEGG: dat:HRM2_33650 hypothetical protein; SPTR: uncharacterized protein YP_004369556.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284:IPR007627:IPR013249; KEGG: slp:Slip_1410 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma factor 70, region 4 type 2; SPTR: RNA polymerase sigma-W factor; TIGRFAM: RNA polymerase sigma-70; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004369557.1 KEGG: sfu:Sfum_2347 hypothetical protein; SPTR: uncharacterized protein YP_004369558.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: pca:Pcar_3111 trehalose phosphorylase/synthase; PFAM: glycosyl transferase, group 1; SPTR: glycosyl transferase, group 1; PFAM: glycosyl transferases group 1 YP_004369559.1 COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR001610:IPR003018:IPR003661:IPR 003594:IPR001789:IPR013656:IPR013655; KEGG: sfu:Sfum_3112 PAS/PAC sensor protein; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; GAF; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; GAF; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: GAF domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004369560.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279:IPR019734:IPR001440; KEGG: fpl:Ferp_1469 TPR repeat-containing protein; PFAM: Beta-lactamase-like; Tetratricopeptide TPR-1; SMART: Beta-lactamase-like; Tetratricopeptide repeat; SPTR: TPR repeat-containing protein; PFAM: Metallo-beta-lactamase superfamily; Tetratricopeptide repeat YP_004369561.1 KEGG: dan:Dana_GF22908 GF22908 gene product from transcript GF22908-RA; SPTR: GF22908 YP_004369562.1 KEGG: fpl:Ferp_1468 hypothetical protein; SPTR: uncharacterized protein YP_004369563.1 KEGG: ptm:GSPATT00012453001 hypothetical protein; SPTR: Chromosome undetermined scaffold_34, whole genome shotgun sequence YP_004369564.1 KEGG: fpl:Ferp_1473 hypothetical protein; SPTR: uncharacterized protein YP_004369565.1 KEGG: fpl:Ferp_1472 hypothetical protein; SPTR: uncharacterized protein YP_004369566.1 COGs: COG1804 acyl-CoA transferase/carnitine dehydratase; InterPro IPR003673; KEGG: fpl:Ferp_1471 L-carnitine dehydratase/bile acid-inducible protein F; PFAM: CoA-transferase III; SPTR: L-carnitine dehydratase/bile acid-inducible protein F; PFAM: CoA-transferase III YP_004369567.1 COGs: COG1804 acyl-CoA transferase/carnitine dehydratase; InterPro IPR003673; KEGG: fpl:Ferp_1470 L-carnitine dehydratase/bile acid-inducible protein F; PFAM: CoA-transferase III; SPTR: L-carnitine dehydratase/bile acid-inducible protein F; PFAM: CoA-transferase III YP_004369568.1 COGs: COG3604 transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR000014:IPR001610:IPR003593:IPR013656:IPR 013767:IPR002078:IPR002197; KEGG: dba:Dbac_2942 two component, sigma54 specific, transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; PAS fold-4; PAS fold; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; PAC motif; PAS; SPTR: Sigma54 specific transcriptional regulator, Fis family; TIGRFAM: PAS; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; PAS fold; TIGRFAM: PAS domain S-box YP_004369569.1 COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR003607:IPR006675:IPR002646:IPR006674; KEGG: dbr:Deba_0672 polynucleotide adenylyltransferase/metal dependent phosphohydrolase; PFAM: poly A polymerase, head domain; Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: polynucleotide adenylyltransferase/metal dependent phosphohydrolase; TIGRFAM: Uncharacterised protein family HDIG; PFAM: HD domain; poly A polymerase head domain; TIGRFAM: uncharacterized domain HDIG YP_004369570.1 COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: dbr:Deba_2710 class II aldolase/adducin family protein; PFAM: Class II aldolase/adducin, N-terminal; PRIAM: L-fuculose-phosphate aldolase; SPTR: Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase YP_004369571.1 KEGG: cby:CLM_0863 hypothetical protein; SPTR: uncharacterized protein YP_004369572.1 KEGG: tmz:Tmz1t_2348 hypothetical protein; SPTR: uncharacterized protein YP_004369573.1 COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterProIPR005757:IPR005758:IPR000713:IPR013221:IPR 004101; KEGG: dak:DaAHT2_1931 UDP-N-acetylmuramate; PFAM: Mur ligase, N-terminal; Mur ligase, central; Mur ligase, C-terminal; PRIAM: UDP-N-acetylmuramate--L-alanine ligase; SPTR: UDP-N-acetylmuramate; TIGRFAM: Murein peptide ligase; UDP-N-acetylmuramate-alanine ligase; PFAM: Mur ligase, glutamate ligase domain; Mur ligase, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diaminopimelate ligase; UDP-N-acetylmuramate--alanine ligase YP_004369574.1 COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: dal:Dalk_3805 beta-lactamase; PFAM: Beta-lactamase-related; SPTR: Beta-lactamase; PFAM: Beta-lactamase YP_004369575.1 COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; HAMAP: D-alanine--D-alanine ligase; InterPro IPR005905:IPR011127:IPR011095; KEGG: sfu:Sfum_4102 D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase, C-terminal; D-alanine--D-alanine ligase, N-terminal; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; TIGRFAM: D-alanine--D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; D-ala D-ala ligase N-terminus; TIGRFAM: D-alanine--D-alanine ligase YP_004369576.1 InterPro IPR006675:IPR006674; KEGG: sfu:Sfum_4103 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SPTR: Metal dependent phosphohydrolase; TIGRFAM: Uncharacterised protein family HDIG; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG YP_004369577.1 COGs: COG3808 Inorganic pyrophosphatase; HAMAP: Pyrophosphate-energised proton pump; InterPro IPR004131; KEGG: sfu:Sfum_3037 membrane-bound proton-translocating pyrophosphatase; PFAM: Pyrophosphate-energised proton pump; PRIAM: Inorganic diphosphatase; SPTR: V-type H(+)-translocating pyrophosphatase; TIGRFAM: Pyrophosphate-energised proton pump; PFAM: Inorganic H+ pyrophosphatase; TIGRFAM: vacuolar-type H(+)-translocating pyrophosphatase YP_004369578.1 COGs: COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family; InterPro IPR003342; KEGG: gme:Gmet_0887 glycosyl transferase; PFAM: glycosyl transferase, family 39; SPTR: glycosyl transferase, family 39; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase YP_004369579.1 COGs: COG0795 permease; InterPro IPR005495; KEGG: gur:Gura_3734 permease YjgP/YjgQ family protein; PFAM: Permease YjgP/YjgQ, predicted; SPTR: Permease YjgP/YjgQ family protein; PFAM: Predicted permease YjgP/YjgQ family YP_004369580.1 COGs: COG1102 Cytidylate kinase; InterPro IPR007055; KEGG: sat:SYN_01443 cytoplasmic protein; PFAM: transport-associated; SPTR: Hypothetical cytosolic protein YP_004369581.1 COGs: COG0861 Membrane protein TerC possibly involved in tellurium resistance; InterPro IPR022301:IPR005496; KEGG: sfu:Sfum_3512 integral membrane protein TerC; PFAM: Integral membrane protein TerC; SPTR: Integral membrane protein TerC; TIGRFAM: Integral membrane protein YjbE; PFAM: Integral membrane protein TerC family; TIGRFAM: integral membrane protein, YjbE family YP_004369582.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: adg:Adeg_2056 radical SAM protein; PFAM: Radical SAM; SPTR: radical SAM protein; PFAM: Radical SAM superfamily YP_004369583.1 COGs: COG3920 Signal transduction histidine kinase; InterPro IPR000014:IPR003594:IPR013656:IPR011495; KEGG: rci:LRC135 signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold-4; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; PAS; SPTR: sensor histidine kinase; TIGRFAM: PAS; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box YP_004369584.1 COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR001789:IPR003661:IPR003594:IPR000014:IPR 013656; KEGG: dal:Dalk_1072 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver domain; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; SPTR: PAS domain S-box protein; TIGRFAM: PAS; PFAM: Response regulator receiver domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004369586.1 COGs: COG0034 glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR005854:IPR000583:IPR000836; KEGG: sfu:Sfum_0007 amidophosphoribosyltransferase; PFAM: glutamine amidotransferase, class-II; phosphoribosyltransferase; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; TIGRFAM: Amidophosphoribosyl transferase; PFAM: phosphoribosyl transferase domain; glutamine amidotransferases class-II; TIGRFAM: amidophosphoribosyltransferase YP_004369587.1 COGs: COG4106 trans-aconitate methyltransferase; InterPro IPR013217; KEGG: bha:BH3909 biotin synthesis BioC proein; PFAM: methyltransferase type 12; SPTR: Biotin synthesis BioC proein; PFAM: methyltransferase domain; TIGRFAM: biotin biosynthesis protein BioC YP_004369588.1 KEGG: afr:AFE_0244 BioH protein; SPTR: BioH protein; manually curated; PFAM: TAP-like protein YP_004369589.1 COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004723:IPR004839; KEGG: gem:GM21_3430 8-amino-7-oxononanoate synthase; PFAM: Aminotransferase, class I/classII; PRIAM: 8-amino-7-oxononanoate synthase; SPTR: 8-amino-7-oxononanoate synthase; TIGRFAM: 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase YP_004369590.1 COGs: COG0132 Dethiobiotin synthetase; HAMAP: Dethiobiotin synthase; InterPro IPR004472:IPR002586; KEGG: gsu:GSU1583 dethiobiotin synthase; PFAM: cobyrinic acid a,c-diamide synthase; SPTR: Dethiobiotin synthetase; TIGRFAM: Dethiobiotin synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: dethiobiotin synthase YP_004369591.1 COGs: COG0502 Biotin synthase; InterPro IPR006638:IPR010722:IPR002684:IPR007197; KEGG: gsu:GSU1584 biotin synthetase; PFAM: Biotin/thiamin synthesis-associated protein; Radical SAM; PRIAM: Biotin synthase; SMART: Elongator protein 3/MiaB/NifB; Biotin/thiamin synthesis-associated protein; SPTR: Biotin synthase; TIGRFAM: Biotin synthase; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: biotin synthetase YP_004369592.1 COGs: COG3065 Starvation-inducible outer membrane lipoprotein; InterPro IPR004658; KEGG: sat:SYN_00736 outer membrane protein Slp precursor; PFAM: Outer membrane lipoprotein Slp; SPTR: Outer membrane lipoprotein, Slp family; PFAM: Outer membrane lipoprotein Slp family; TIGRFAM: outer membrane lipoprotein, Slp family YP_004369593.1 KEGG: nhl:Nhal_3579 hypothetical protein; SPTR: Membrane protein YP_004369594.1 KEGG: eay:EAM_1676 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1640) YP_004369595.1 KEGG: sgl:SG1560 hypothetical protein; SPTR: uncharacterized protein YP_004369596.1 KEGG: lki:LKI_10591 plasmid mobilization protein, truncated; SPTR: Predicted protein YP_004369597.1 KEGG: dsa:Desal_2743 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA binding domain, excisionase YP_004369599.1 KEGG: pth:PTH_1394 hypothetical protein; SPTR: uncharacterized protein YP_004369600.1 COGs: COG0358 DNA primase; InterPro IPR013237:IPR002694; KEGG: dal:Dalk_0267 P4 alpha zinc-binding domain protein; PFAM: Phage P4 alpha, zinc-binding; SMART: Phage P4 alpha, zinc-binding; Zinc finger, CHC2-type; SPTR: P4 alpha zinc-binding domain protein; PFAM: Zinc-binding domain of primase-helicase YP_004369601.1 KEGG: nvi:100115768 similar to polymerase (RNA) III (DNA directed) polypeptide E; SPTR: uncharacterized protein YP_004369602.1 KEGG: fpl:Ferp_2229 ribosomal protein S27a; SPTR: 30S ribosomal protein S27ae; PFAM: ribosomal protein S27a YP_004369603.1 KEGG: cac:CA_C1607 hypothetical protein; SPTR: Hypothetical phage protein; PFAM: Domain of Unknown Function (DUF1599) YP_004369604.1 COGs: COG1948 ERCC4-type nuclease; InterPro IPR006166; KEGG: sfu:Sfum_3998 hypothetical protein; PFAM: ERCC4 domain; SMART: ERCC4 domain; SPTR: ERCC4 domain protein YP_004369605.1 KEGG: lhk:LHK_01525 hypothetical protein; SPTR: transcriptional coactivator p15; PFAM: transcriptional Coactivator p15 (PC4) YP_004369606.1 KEGG: mmu:100986 hypothetical protein; SPTR: A-kinase anchor protein 9 YP_004369607.1 KEGG: dbr:Deba_0112 hypothetical protein; SPTR: uncharacterized protein YP_004369609.1 KEGG: tde:TDE2786 DNA polymerase III subunit alpha; SPTR: uncharacterized protein YP_004369610.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: dal:Dalk_2810 integrase; PFAM: Integrase, catalytic core, phage; SPTR: Integrase; PFAM: Phage integrase YP_004369611.1 COGs: COG0674 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR019752:IPR001450:IPR011766; KEGG: cno:NT01CX_1854 pyruvate:ferredoxin (flavodoxin) oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; pyruvate/ketoisovalerate oxidoreductase, catalytic domain; 4Fe-4S binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: pyruvate dehydrogenase (NADP(+))., 2-oxoglutarate synthase; SPTR: pyruvate-flavodoxin oxidoreductase; PFAM: domain; pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain YP_004369612.1 KEGG: sfu:Sfum_3241 hypothetical protein; SPTR: uncharacterized protein YP_004369613.1 COGs: COG1399 metal-binding possibly nucleic acid-binding protein; InterPro IPR003772; KEGG: sfu:Sfum_1368 hypothetical protein; PFAM: protein of unknown function DUF177; SPTR: uncharacterized protein; PFAM: Uncharacterized ACR, COG1399 YP_004369614.1 COGs: COG0333 ribosomal protein L32; HAMAP: ribosomal protein L32p; InterPro IPR002677; KEGG: dal:Dalk_3305 ribosomal protein L32; PFAM: ribosomal protein L32p; SPTR: 50S ribosomal protein L32; TIGRFAM: ribosomal protein L32p; PFAM: ribosomal L32p protein family; TIGRFAM: ribosomal protein L32 YP_004369615.1 COGs: COG1960 acyl-CoA dehydrogenase; InterPro IPR006092:IPR006091:IPR006090; KEGG: dbr:Deba_2391 acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA oxidase/dehydrogenase, type 1; acyl-CoA dehydrogenase, N-terminal; acyl-CoA oxidase/dehydrogenase, central domain; PRIAM: Butyryl-CoA dehydrogenase; SPTR: acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase, C-terminal domain; acyl-CoA dehydrogenase, middle domain; acyl-CoA dehydrogenase, N-terminal domain YP_004369616.1 COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR014730; KEGG: dak:DaAHT2_1288 electron transfer flavoprotein alpha/beta-subunit; PFAM: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SMART: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SPTR: Electron transfer flavoprotein alpha/beta-subunit; PFAM: Electron transfer flavoprotein domain YP_004369617.1 COGs: COG2025 Electron transfer flavoprotein alpha subunit; InterPro IPR014730:IPR001450:IPR014731; KEGG: dak:DaAHT2_1287 electron transfer flavoprotein alpha/beta-subunit; PFAM: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; 4Fe-4S binding domain; Electron transfer flavoprotein, alpha subunit, C-terminal; SMART: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SPTR: Electron transfer flavoprotein alpha/beta-subunit; PFAM: 4Fe-4S binding domain; Electron transfer flavoprotein domain; Electron transfer flavoprotein FAD-binding domain YP_004369618.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020842:IPR011284:IPR002198; KEGG: gmc:GY4MC1_2719 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Short-chain dehydrogenase/reductase SDR; SMART: polyketide synthase/Fatty acid synthase, KR; SPTR: 3-oxoacyl-(acyl-carrier-protein) reductase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short chain dehydrogenase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase YP_004369619.1 COGs: COG0236 acyl carrier protein; HAMAP: acyl carrier protein (ACP); InterPro IPR003231:IPR006163; KEGG: toc:Toce_1058 acyl carrier protein; PFAM: phosphopantetheine-binding; SPTR: acyl carrier protein; TIGRFAM: acyl carrier protein (ACP); PFAM: phosphopantetheine attachment site; TIGRFAM: acyl carrier protein YP_004369620.1 COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR020841:IPR017568:IPR014030:IPR014031; KEGG: gur:Gura_1879 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase II; SMART: polyketide synthase, beta-ketoacyl synthase domain; SPTR: Beta-ketoacyl-acyl-carrier-protein synthase II; TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: beta-ketoacyl-acyl-carrier-protein synthase II YP_004369621.1 COGs: COG0698 ribose 5-phosphate isomerase RpiB; InterPro IPR004785:IPR003500; KEGG: ddf:DEFDS_0484 ribose 5-phosphate isomerase B; PFAM: ribose/galactose isomerase; PRIAM: ribose-5-phosphate isomerase; SPTR: ribose 5-phosphate isomerase B; TIGRFAM: ribose/galactose isomerase; ribose 5-phosphate isomerase B; PFAM: ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family YP_004369622.1 COGs: COG0112 glycine/serine hydroxymethyltransferase; InterPro IPR001085; KEGG: sfu:Sfum_1377 glycine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase; PRIAM: glycine hydroxymethyltransferase; SPTR: Serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase YP_004369623.1 COGs: COG1327 transcriptional regulator protein consists of a Zn-ribbon and ATP-cone domains; HAMAP: ribonucleotide reductase regulator NrdR-like; InterPro IPR003796:IPR005144; KEGG: mxa:MXAN_4765 transcriptional regulator NrdR; PFAM: ATP-cone; SPTR: transcriptional repressor NrdR; TIGRFAM: ribonucleotide reductase regulator NrdR-like; PFAM: ATP cone domain; TIGRFAM: transcriptional regulator NrdR YP_004369624.1 COGs: COG1895 conserved hypothetical protein related to C-terminal domain of eukaryotic chaperone SACSIN; InterPro IPR007842; KEGG: tko:TK1072 hypothetical protein; PFAM: HEPN; SPTR: toxin-antitoxin system, antitoxin component; PFAM: HEPN domain YP_004369625.1 InterPro IPR002934; KEGG: dae:Dtox_4035 DNA polymerase beta domain protein region; PFAM: nucleotidyl transferase domain; SPTR: DNA polymerase beta domain protein region; PFAM: nucleotidyltransferase domain YP_004369626.1 COGs: COG0863 DNA modification methylase; InterPro IPR002941; KEGG: geo:Geob_0583 DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase N-4/N-6; SPTR: DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase YP_004369627.1 COGs: COG1985 Pyrimidine reductase riboflavin biosynthesis; InterPro IPR004794:IPR011549:IPR002125:IPR002734; KEGG: mta:Moth_0915 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal; CMP/dCMP deaminase, zinc-binding; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase., 5-amino-6-(5-phosphoribosylamino)uracil reductase; SPTR: 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase; TIGRFAM: riboflavin biosynthesis protein RibD; riboflavin-specific deaminase, C-terminal; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin-specific deaminase C-terminal domain; riboflavin biosynthesis protein RibD YP_004369628.1 COGs: COG0124 histidyl-tRNA synthetase; HAMAP: histidyl-tRNA synthetase, class IIa, subgroup; InterPro IPR015807:IPR002314:IPR004154; KEGG: sat:SYN_02534 histidyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; PRIAM: histidine--tRNA ligase; SPTR: histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase, class IIa, subgroup; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase YP_004369629.1 COGs: COG0173 aspartyl-tRNA synthetase; InterPro IPR004524:IPR004365:IPR004364:IPR004115; KEGG: dak:DaAHT2_2033 aspartyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; GAD domain; PRIAM: aspartate--tRNA ligase; SPTR: aspartyl-tRNA synthetase; TIGRFAM: aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type; PFAM: GAD domain; tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: aspartyl-tRNA synthetase, bacterial type YP_004369630.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR004010; KEGG: sfu:Sfum_3301 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; Cache; SPTR: pyruvate carboxyltransferase; PFAM: Cache domain; HMGL-like YP_004369631.1 InterPro IPR002781; KEGG: dvm:DvMF_2812 protein of unknown function DUF81; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004369632.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: rva:Rvan_1243 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: Cell wall hydrolase/autolysin; PFAM: N-acetylmuramoyl-L-alanine amidase YP_004369634.1 KEGG: tye:THEYE_A0699 lipoprotein, SPTR: uncharacterized protein YP_004369635.1 COGs: COG1884 methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006098:IPR006099; KEGG: tte:TTE1217 methylmalonyl-CoA mutase N-terminal domain-containing protein; PFAM: methylmalonyl-CoA mutase, alpha/beta chain, catalytic; PRIAM: methylmalonyl-CoA mutase; SPTR: methylmalonyl-CoA mutase N-terminal domain protein; TIGRFAM: methylmalonyl-CoA mutase, alpha chain, catalytic; PFAM: methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain YP_004369636.1 COGs: COG2185 methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding); InterPro IPR006159:IPR006158; KEGG: dbr:Deba_0883 cobalamin B12-binding domain protein; PFAM: Cobalamin (vitamin B12)-binding; SPTR: Cobalamin B12-binding domain protein; TIGRFAM: methylmalonyl-CoA mutase, C-terminal; PFAM: B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain YP_004369637.1 COGs: COG0469 pyruvate kinase; InterPro IPR001697:IPR015793:IPR015795; KEGG: gur:Gura_2655 pyruvate kinase; PFAM: pyruvate kinase, barrel; pyruvate kinase, C-terminal-like; PRIAM: pyruvate kinase; SPTR: pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: pyruvate kinase, barrel domain; pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase YP_004369638.1 KEGG: vvi:100242141 hypothetical protein LOC100242141; SPTR: Whole genome shotgun sequence of line PN40024, scaffold_44.assembly12x YP_004369639.1 KEGG: ehi:EHI_159730 glycylpeptide N-tetradecanoyltransferase; SPTR: uncharacterized protein YP_004369640.1 COGs: COG4313 protein involved in meta-pathway of phenol degradation; KEGG: sat:SYN_00385 hypothetical protein; SPTR: Hypothetical exported protein YP_004369641.1 COGs: COG1117 ABC-type phosphate transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: sfu:Sfum_0283 ABC transporter related; PFAM: ABC transporter-like; PRIAM: phosphate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter YP_004369642.1 COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR000515; KEGG: sfu:Sfum_0284 phosphate ABC transporter, inner membrane subunit PstA; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: phosphate ABC transporter, inner membrane subunit PstA; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease PstA YP_004369643.1 COGs: COG0573 ABC-type phosphate transport system permease component; InterPro IPR000515; KEGG: sfu:Sfum_0285 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004369644.1 COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR011862; KEGG: sfu:Sfum_0286 phosphate binding protein; SPTR: phosphate binding protein; TIGRFAM: phosphate binding protein; TIGRFAM: phosphate binding protein YP_004369645.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR006638:IPR007197; KEGG: sta:STHERM_c03460 FeMo cofactor biosynthesis protein NifB; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: FeMo cofactor biosynthesis protein NifB; PFAM: Radical SAM superfamily; TIGRFAM: nitrogenase cofactor biosynthesis protein NifB YP_004369646.1 COGs: COG0348 polyferredoxin; InterPro IPR001450; KEGG: sfu:Sfum_1960 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_004369647.1 COGs: COG0725 ABC-type molybdate transport system periplasmic component; InterPro IPR006311; KEGG: sfu:Sfum_1959 molybdenum ABC transporter, solute-binding protein; SPTR: molybdenum ABC transporter, solute-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein YP_004369648.1 COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260; KEGG: msl:Msil_0824 TonB family protein; PFAM: TonB, C-terminal; SPTR: TonB-dependent receptor, ; TIGRFAM: TonB, C-terminal; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain YP_004369649.1 COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: bba:Bd0478 TonB system transport protein ExbD2; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: uncharacterized protein; PFAM: Biopolymer transport protein ExbD/TolR YP_004369650.1 COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: hoh:Hoch_4648 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family YP_004369651.1 COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: sfu:Sfum_2739 ABC transporter related; PFAM: ABC transporter-like; PRIAM: iron ABC transporter ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter YP_004369652.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: sfu:Sfum_2740 transport system permease; PFAM: ABC transporter permease; SPTR: transport system permease; PFAM: FecCD transport family YP_004369653.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: dol:Dole_2060 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: uncharacterized protein; PFAM: Periplasmic binding protein YP_004369654.1 KEGG: dal:Dalk_1089 hypothetical protein; SPTR: uncharacterized protein YP_004369655.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491:IPR002808; KEGG: sfu:Sfum_2743 hypothetical protein; PFAM: adenosylcobinamide amidohydrolase, CbiZ; Periplasmic binding protein; SPTR: uncharacterized protein; PFAM: Periplasmic binding protein; adenosylcobinamide amidohydrolase YP_004369656.1 COGs: COG4206 Outer membrane cobalamin receptor protein; InterPro IPR012910:IPR000531; KEGG: pca:Pcar_0454 TonB-dependent outer membrane receptor for cobalamin and Fe transport; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; SPTR: TonB-dependent outer membrane receptor for cobalamin and Fe transport; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004369657.1 KEGG: dol:Dole_1858 hypothetical protein; SPTR: uncharacterized protein YP_004369658.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR000014:IPR003594:IPR001789:IPR013656; KEGG: gsu:GSU1529 sensory box histidine kinase/response regulator; PFAM: ATPase-like, ATP-binding domain; PAS fold-4; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; PAS; Signal transduction response regulator, receiver domain; SPTR: Sensory box histidine kinase/response regulator; TIGRFAM: PAS; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box YP_004369659.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR007197; KEGG: sfu:Sfum_3475 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: radical SAM protein; manually curated; PFAM: Radical SAM superfamily YP_004369660.1 COGs: COG0206 Cell division GTPase; InterPro IPR003008:IPR018316:IPR000158; KEGG: sat:SYN_00437 cell division protein FtsZ; PFAM: Tubulin/FtsZ, GTPase domain; Tubulin/FtsZ, 2-layer sandwich domain; SMART: Tubulin/FtsZ, GTPase domain; Tubulin/FtsZ, 2-layer sandwich domain; SPTR: Cell division protein ftsZ; TIGRFAM: Cell division protein FtsZ, N-terminal; PFAM: Tubulin/FtsZ family, GTPase domain; FtsZ family, C-terminal domain; TIGRFAM: cell division protein FtsZ YP_004369661.1 COGs: COG0849 Actin-like ATPase involved in cell division; InterPro IPR003494:IPR020823; KEGG: geo:Geob_0785 cell division protein FtsA; PFAM: Cell division protein FtsA domain; SMART: Cell division protein FtsA domain; SPTR: Cell division protein FtsA; TIGRFAM: Cell division protein family FtsA; PFAM: Cell division protein FtsA; TIGRFAM: cell division protein FtsA YP_004369662.1 COGs: COG1589 Cell division septal protein; InterPro IPR013685; KEGG: dol:Dole_2784 polypeptide-transport-associated domain-containing protein; PFAM: polypeptide-transport-associated, FtsQ-type; SPTR: polypeptide-transport-associated domain protein FtsQ-type; PFAM: Cell division protein FtsQ; POTRA domain, FtsQ-type YP_004369663.1 COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; HAMAP: UDP-N-acetylmuramate-alanine ligase; InterPro IPR005758:IPR000713:IPR013221:IPR004101; KEGG: dol:Dole_2786 UDP-N-acetylmuramate--alanine ligase; PFAM: Mur ligase, N-terminal; Mur ligase, central; Mur ligase, C-terminal; PRIAM: UDP-N-acetylmuramate--L-alanine ligase; SPTR: UDP-N-acetylmuramate--L-alanine ligase; TIGRFAM: UDP-N-acetylmuramate-alanine ligase; PFAM: Mur ligase, catalytic domain; Mur ligase, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate--alanine ligase YP_004369664.1 COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; HAMAP: N-acetylglucosaminyltransferase, MurG; InterPro IPR006009:IPR004276:IPR007235; KEGG: gsu:GSU3069 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; PFAM: glycosyl transferase, family 28, C-terminal; glycosyl transferase, family 28; PRIAM: Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; SPTR:UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; TIGRFAM: N-acetylglucosaminyltransferase, MurG; PFAM: glycosyltransferase 28 C-terminal domain; glycosyltransferase 28 N-terminal domain; TIGRFAM: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase YP_004369665.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437:IPR001182; KEGG: glo:Glov_0671 cell division protein FtsW; PFAM: Cell cycle protein; SPTR: Cell division protein FtsW; TIGRFAM: Cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; cell division protein FtsW YP_004369666.1 COGs: COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; HAMAP: UDP-N-acetylmuramoylalanine-D-glutamate ligase; InterPro IPR005762:IPR013221:IPR004101; KEGG: geo:Geob_0778 UDP-N-acetylmuramoylalanine/D-glutamate ligase; PFAM: Mur ligase, central; Mur ligase, C-terminal; SPTR: UDP-N-acetylmuramoylalanine--D-glutamate ligase; TIGRFAM: UDP-N-acetylmuramoylalanine-D-glutamate ligase; PFAM: Mur ligase, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_004369667.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; HAMAP: phospho-N-acetylmuramoyl-pentapeptide transferase; InterPro IPR003524:IPR018480:IPR000715; KEGG: dbr:Deba_2790 phospho-N-acetylmuramoyl-pentapeptide-transferas E; PFAM: glycosyl transferase, family 4; phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site; SPTR: phospho-N-acetylmuramoyl-pentapeptide-transferas e; TIGRFAM: phospho-N-acetylmuramoyl-pentapeptide transferase; PFAM: glycosyl transferase 4; phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1; TIGRFAM: phospho-N-acetylmuramoyl-pentapeptide-transferase YP_004369668.1 COGs: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; InterPro IPR005863:IPR000713:IPR013221:IPR004101; KEGG: gem:GM21_0504 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/ D-alanyl-D -alanyl ligase; PFAM: Mur ligase, central; Mur ligase, N-terminal; Mur ligase, C-terminal; PRIAM:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-a lanineligase; SPTR:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al anineligase; TIGRFAM: UDP-MurNAc-pentapeptide synthetase; PFAM: Mur ligase, glutamate ligase domain; Mur ligase, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_004369669.1 COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; HAMAP:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-di aminopimelateligase; InterPro IPR005761:IPR000713:IPR013221:IPR004101; KEGG: gem:GM21_0503 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase; PFAM: Mur ligase, central; Mur ligase, N-terminal; Mur ligase, C-terminal; PRIAM:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelateligase; SPTR: UDP-N-acetylmuramyl-tripeptide synthetase; TIGRFAM:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelateligase; PFAM: Mur ligase, glutamate ligase domain; Mur ligase, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase YP_004369670.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460:IPR005543; KEGG: ppd:Ppro_3295 peptidoglycan glycosyltransferase; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA; PRIAM: peptidoglycan glycosyltransferase; SPTR: peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding protein dimerisation domain; PASTA domain YP_004369671.1 InterPro IPR007060; KEGG: sat:SYN_01738 hypothetical protein; PFAM: Septum formation initiator; SPTR: Hypothetical membrane protein; PFAM: Cell division protein FtsL; TIGRFAM: cell division protein FtsL YP_004369672.1 COGs: COG0275 S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; HAMAP: S-adenosyl-L-methionine-dependent methyltransferase, MraW; InterPro IPR002903; KEGG: adg:Adeg_1572 S-adenosyl-methyltransferase MraW; PFAM: S-adenosyl-L-methionine-dependent methyltransferase, MraW; SPTR: ribosomal RNA small subunit methyltransferase H; TIGRFAM: S-adenosyl-L-methionine-dependent methyltransferase, MraW; PFAM: MraW methylase; TIGRFAM: S-adenosyl-methyltransferase MraW YP_004369673.1 COGs: COG2001 conserved hypothetical protein; HAMAP: MraZ; InterPro IPR003444:IPR020603; KEGG: sat:SYN_01736 cell division protein; PFAM: MraZ domain; SPTR: protein MraZ; TIGRFAM: MraZ; PFAM: MraZ protein; TIGRFAM: mraZ protein YP_004369674.1 COGs: COG0320 Lipoate synthase; InterPro IPR006638:IPR007197; KEGG: slp:Slip_2183 lipoic acid synthetase; PFAM: Radical SAM; PRIAM: Lipoyl synthase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Lipoic acid synthetase; PFAM: Radical SAM superfamily; TIGRFAM: lipoate synthase YP_004369675.1 COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593:IPR018541:IPR002543; KEGG: gur:Gura_4392 cell divisionFtsK/SpoIIIE; PFAM: Cell divisionFtsK/SpoIIIE; DNA translocase FtsK gamma; SMART: DNA translocase FtsK gamma; ATPase, AAA+ type, core; SPTR: FtsK/SpoIIIE family protein; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family YP_004369676.1 InterPro IPR019284; KEGG: cyh:Cyan8802_2678 hypothetical protein; PFAM: protein of unknown function DUF2335, membrane; SPTR: uncharacterized protein; PFAM: Predicted membrane protein (DUF2335) YP_004369677.1 InterPro IPR002941:IPR013216; KEGG: mhu:Mhun_3051 methyltransferase DNA modification enzyme; PFAM: DNA methylase N-4/N-6; methyltransferase type 11; SPTR: methyltransferase DNA modification enzyme; PFAM: DNA methylase YP_004369678.1 COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: rmr:Rmar_2495 DNA polymerase beta domain protein region; PFAM: nucleotidyl transferase domain; SPTR: DNA polymerase beta domain protein region; PFAM: nucleotidyltransferase domain YP_004369679.1 COGs: COG2361 conserved hypothetical protein; InterPro IPR008201; KEGG: gur:Gura_4166 hypothetical protein; PFAM: protein of unknown function DUF86; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF86 YP_004369680.1 KEGG: apo:Arcpr_1687 hypothetical protein; SPTR: uncharacterized protein YP_004369681.1 InterPro IPR013423; KEGG: hdn:Hden_1124 protein of unknown function DUF847; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP02594; TIGRFAM: TIGR02594 family protein YP_004369682.1 InterPro IPR001387; KEGG: sml:Smlt1898 HTH transcriptional regulator; SMART: Helix-turn-helix type 3; SPTR: XRE family transcriptional regulator; PFAM: Helix-turn-helix YP_004369683.1 InterPro IPR010359; KEGG: sez:Sez_0307 transcriptional regulator; PFAM: protein of unknown function DUF955; SPTR: transcriptional regulator; PFAM: Domain of unknown function (DUF955) YP_004369684.1 KEGG: meh:M301_2497 hypothetical protein; SPTR: uncharacterized protein YP_004369685.1 KEGG: afw:Anae109_1487 response regulator receiver protein; SPTR: Response regulator receiver protein YP_004369686.1 KEGG: hha:Hhal_0784 transposase, IS4 family protein; SPTR: transposase, IS4 family protein YP_004369687.1 KEGG: hau:Haur_1388 hypothetical protein; SPTR: uncharacterized protein YP_004369688.1 KEGG: hau:Haur_1389 hypothetical protein; SPTR: uncharacterized protein YP_004369689.1 KEGG: pth:PTH_2566 hypothetical protein; SPTR: uncharacterized protein YP_004369690.1 COGs: COG1078 HD superfamily phosphohydrolase; InterPro IPR003607:IPR006674; KEGG: pth:PTH_2567 phosphohydrolases; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: uncharacterized protein; PFAM: HD domain YP_004369691.1 COGs: COG0590 Cytosine/adenosine deaminase; InterPro IPR002125; KEGG: sat:SYN_00164 tRNA-specific adenosine deaminase; PFAM: CMP/dCMP deaminase, zinc-binding; SPTR: tRNA-specific adenosine deaminase; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_004369692.1 KEGG: dal:Dalk_3601 TPR repeat-containing protein; SPTR: TPR repeat-containing protein YP_004369693.1 KEGG: mev:Metev_1517 hypothetical protein; SPTR: Bacterial type II secretion system protein F domain YP_004369694.1 KEGG: spa:M6_Spy1546 unknown phage protein; SPTR: Cell division protein Smc YP_004369695.1 COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; HAMAP: 5-methylthioadenosine/S-adenosylhomocysteine deaminase; InterPro IPR006680; KEGG: dal:Dalk_2439 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase; PFAM: Amidohydrolase YP_004369696.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR003593:IPR002078; KEGG: drt:Dret_0168 PAS modulated sigma54 specific transcriptional regulator, Fis family; PFAM: RNA polymerase sigma factor 54, interaction; SMART: ATPase, AAA+ type, core; SPTR: PAS modulated sigma54 specific transcriptional regulator, Fis family; PFAM: Sigma-54 interaction domain YP_004369697.1 KEGG: dsa:Desal_2428 tetratricopeptide TPR_2 repeat protein; SPTR: Tetratricopeptide TPR_2 repeat protein YP_004369698.1 InterPro IPR007412; KEGG: ncr:NCU07868 hypothetical protein; PFAM: Anti-sigma-28 factor, FlgM; SPTR: Chromosome 17 SCAF15006, whole genome shotgun sequence.; PFAM: Anti-sigma-28 factor, FlgM YP_004369699.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR006158:IPR007197; KEGG: slp:Slip_0515 radical SAM protein; PFAM: Radical SAM; Cobalamin (vitamin B12)-binding; SMART: Elongator protein 3/MiaB/NifB; SPTR: cobalamin B12-binding/Radical SAM family protein; PFAM: Radical SAM superfamily; B12 binding domain YP_004369700.1 COGs: COG2920 Dissimilatory sulfite reductase (desulfoviridin) gamma subunit; InterPro IPR007453; KEGG: dma:DMR_15890 sulfite reductase gamma subunit; PFAM: DsrC-like protein; PRIAM: Hydrogensulfite reductase; SPTR: Sulfite reductase gamma subunit; TIGRFAM: DsrC-like protein; PFAM: DsrC like protein; TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family YP_004369701.1 COGs: COG0247 Fe-S oxidoreductase; InterPro IPR001450:IPR004017; KEGG: gsu:GSU1624 glycolate oxidase iron-sulfur subunit; PFAM: cysteine-rich domain; 4Fe-4S binding domain; SPTR: glycolate oxidase iron-sulfur subunit, ; PFAM: cysteine-rich domain YP_004369702.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: dol:Dole_0002 FAD linked oxidase domain-containing protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: FAD linked oxidase domain protein; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD YP_004369703.1 COGs: COG2217 Cation transport ATPase; InterProIPR006121:IPR008250:IPR005834:IPR006403:IPR 006416:IPR001757; KEGG: sat:SYN_01290 copper-exporting ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase; PRIAM: Copper-exporting ATPase; SPTR: Copper-exporting ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P type, cation/copper-transporter; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004369704.1 KEGG: sno:Snov_2285 hypothetical protein; SPTR: uncharacterized protein YP_004369705.1 KEGG: rca:Rcas_2445 hypothetical protein; SPTR: uncharacterized protein YP_004369706.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: gme:Gmet_2408 secretion protein HlyD; PFAM: Secretion protein HlyD; SPTR: Secretion protein HlyD; TIGRFAM: Secretion protein HlyD; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004369707.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: gur:Gura_1457 ABC transporter related; PFAM: ABC transporter-like; PRIAM: sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter YP_004369708.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: ppd:Ppro_1985 hypothetical protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004369709.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: gme:Gmet_2405 hypothetical protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004369710.1 COGs: COG0128 5-enolpyruvylshikimate-3-phosphate synthase; HAMAP: 3-phosphoshikimate 1-carboxyvinyltransferase; InterPro IPR001986:IPR006264; KEGG: dol:Dole_1949 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: Enolpyruvate transferase domain; PRIAM: 3-phosphoshikimate 1-carboxyvinyltransferase; SPTR: 3-phosphoshikimate 1-carboxyvinyltransferase; TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase YP_004369711.1 COGs: COG0169 shikimate 5-dehydrogenase; HAMAP: shikimate, quinate/shikimate dehydrogenase; InterPro IPR013708:IPR006151:IPR022893:IPR011342; KEGG: dak:DaAHT2_0009 shikimate 5-dehydrogenase; PFAM: shikimate dehydrogenase substrate binding, N-terminal; Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase; SPTR: shikimate dehydrogenase 2; TIGRFAM: shikimate dehydrogenase; PFAM: shikimate dehydrogenase substrate binding domain; shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase YP_004369712.1 COGs: COG0710 3-dehydroquinate dehydratase; HAMAP: Dehydroquinase class I; InterPro IPR001381; KEGG: sat:SYN_01938 3-dehydroquinate dehydratase; PFAM: Dehydroquinase class I; PRIAM: 3-dehydroquinate dehydratase; SPTR: 3-dehydroquinate dehydratase; TIGRFAM: Dehydroquinase class I; PFAM: Type I 3-dehydroquinase; TIGRFAM: 3-dehydroquinate dehydratase, type I YP_004369713.1 COGs: COG0077 Prephenate dehydratase; InterPro IPR002701:IPR020822:IPR001086:IPR002912; KEGG: glo:Glov_2150 chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT; SMART: Chorismate mutase; SPTR: Chorismate mutase; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II YP_004369714.1 COGs: COG1465 alternative 3-dehydroquinate synthase; HAMAP: 3-dehydroquinate synthase; InterPro IPR002812; KEGG: dol:Dole_1951 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase, prokaryotic-type; SPTR: 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase YP_004369715.1 COGs: COG1830 DhnA-type fructose-1 6-bisphosphate aldolase; InterPro IPR002915:IPR010210; KEGG: dol:Dole_1952 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Fructose-bisphosphate aldolase; SPTR: Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: predicted phospho-2-dehydro-3-deoxyheptonate aldolase YP_004369716.1 COGs: COG5266 ABC-type Co2+ transport system periplasmic component; InterPro IPR019613; KEGG: oan:Oant_4175 hypothetical protein; PFAM: Nickel transport complex, NikM subunit, transmembrane; SPTR: ABC-type Co2+ transport system, periplasmic component; PFAM: Nickel uptake substrate-specific transmembrane region YP_004369717.1 KEGG: vei:Veis_0670 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1640) YP_004369718.1 COGs: COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; InterPro IPR014001:IPR001650:IPR011545:IPR005259; KEGG: gur:Gura_0374 primosomal protein N'; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: Primosomal protein N'; TIGRFAM: Primosomal protein n; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: primosomal protein N' YP_004369719.1 COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR019591; KEGG: sfu:Sfum_1303 hypothetical protein; PFAM: ATPase-like, ParA/MinD; SPTR: Dinitrogenase iron-molybdenum cofactor; PFAM: ParA/MinD ATPase like YP_004369720.1 COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR000644:IPR001093:IPR005990; KEGG: gme:Gmet_2293 inosine-5'-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; cystathionine beta-synthase, core; PRIAM: IMP dehydrogenase; SMART: cystathionine beta-synthase, core; SPTR: Inosine-5'-monophosphate dehydrogenase; TIGRFAM: IMP dehydrogenase; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase YP_004369721.1 InterPro IPR013217; KEGG: dbr:Deba_1314 methyltransferase type 12; PFAM: methyltransferase type 12; SPTR: methyltransferase type 12; PFAM: O-methyltransferase YP_004369722.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: emi:Emin_0880 ABC transporter related; PFAM: ABC transporter-like; ABC transporter, transmembrane domain; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, permease/ATP-binding protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004369723.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: emi:Emin_0879 ABC transporter related; PFAM: ABC transporter-like; ABC transporter, transmembrane domain; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, permease/ATP-binding protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004369724.1 InterPro IPR011701; KEGG: wsu:WS1266 hypothetical protein; PFAM: Major facilitator superfamily MFS-1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004369725.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910:IPR000531:IPR010105; KEGG: sdl:Sdel_1574 TonB-dependent receptor; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; SPTR: TonB-dependent siderophore receptor; TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor; TIGRFAM: TonB-dependent siderophore receptor YP_004369726.1 COGs: COG3315 O-methyltransferase involved in polyketide biosynthesis; KEGG: mac:MA3472 hypothetical protein; SPTR: O-methyltransferase domain protein; PFAM: Leucine carboxyl methyltransferase YP_004369727.1 KEGG: mgr:MGG_08467 hypothetical protein YP_004369728.1 InterPro IPR008554; KEGG: dat:HRM2_42580 HAD family hydrolase; PFAM: glutaredoxin-like; SPTR: HAD family hydrolase YP_004369729.1 KEGG: pam:PANA_1965 YdfG; SPTR: YdfG YP_004369730.1 COGs: COG1150 Heterodisulfide reductase subunit C; KEGG: sfu:Sfum_1806 heterodisulfide reductase, C subunit; SPTR: Heterodisulfide reductase, C subunit YP_004369731.1 COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: sfu:Sfum_1805 hypothetical protein; PFAM: cysteine-rich domain; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: uncharacterized protein; PFAM: cysteine-rich domain YP_004369732.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR002218:IPR001450:IPR013027:IPR003953; KEGG: dat:HRM2_30890 HdrL3; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S binding domain; glucose-inhibited division protein A-related; Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; PRIAM: glutamate synthase (NADPH); SPTR: HdrL3; PFAM: Pyridine nucleotide-disulphide oxidoreductase; glucose inhibited division protein A YP_004369733.1 COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: dbr:Deba_2477 alkaline phosphatase; PFAM: Alkaline phosphatase; PRIAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; PFAM: Alkaline phosphatase YP_004369734.1 COGs: COG0057 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006424; KEGG: fbc:FB2170_00180 glyceraldehyde 3-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SMART: glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; SPTR: glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I YP_004369735.1 COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR000836:IPR005904; KEGG: sfu:Sfum_1422 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase; PFAM: phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase YP_004369736.1 KEGG: sfu:Sfum_2300 hypothetical protein; SPTR: uncharacterized protein YP_004369737.1 KEGG: gbm:Gbem_3184 hypothetical protein; SPTR: uncharacterized protein YP_004369738.1 KEGG: dba:Dbac_1088 hypothetical protein; SPTR: uncharacterized protein YP_004369739.1 COGs: COG0702 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: sfu:Sfum_3376 NmrA family protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NmrA family protein; PFAM: protein of unknown function (DUF2867); NmrA-like family YP_004369740.1 KEGG: rmr:Rmar_2214 molybdenum cofactor biosynthesis protein A YP_004369741.1 COGs: COG0171 NAD synthase; InterPro IPR003010:IPR022310:IPR003694; KEGG: slp:Slip_1570 NAD+ synthetase; PFAM: NAD/GMP synthase; nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: NAD+ synthetase; TIGRFAM: NAD synthase; PFAM: NAD synthase; Carbon-nitrogen hydrolase; TIGRFAM: NAD+ synthetase YP_004369742.1 COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; InterPro IPR001279; KEGG: mpl:Mpal_1437 beta-lactamase domain protein; PFAM: Beta-lactamase-like; SPTR: Beta-lactamase domain-containing protein; PFAM: Metallo-beta-lactamase superfamily YP_004369743.1 COGs: COG1158 transcription termination factor; InterProIPR011112:IPR011129:IPR003593:IPR011113:IPR 000194:IPR004665; KEGG: dbr:Deba_0734 transcription termination factor Rho; PFAM: ATPase, alpha/beta subunit, nucleotide-binding domain; Rho termination factor, RNA-binding; Rho termination factor, N-terminal; SMART: Cold shock protein; Rho termination factor, N-terminal; ATPase, AAA+ type, core; SPTR: transcription termination factor Rho; TIGRFAM: transcription termination factor Rho; PFAM: Rho termination factor, N-terminal domain; Rho termination factor, RNA-binding domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: transcription termination factor Rho YP_004369744.1 COGs: COG0237 Dephospho-CoA kinase; HAMAP: Dephospho-CoA kinase; InterPro IPR001977; KEGG: bbe:BBR47_14070 dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; PRIAM: Dephospho-CoA kinase; SPTR: Dephospho-CoA kinase; TIGRFAM: Dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase YP_004369745.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942:IPR006145:IPR006225; KEGG: sat:SYN_01800 ribosomal large subunit pseudouridine synthase D; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RluC/RluD; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family YP_004369746.1 COGs: COG4956 Integral membrane protein (PIN domain superfamily); InterPro IPR006596:IPR002716:IPR002792; KEGG: sfu:Sfum_3656 twitching mobility protein PilT; PFAM: PilT protein, N-terminal; Deoxyribonuclease/rho motif-related TRAM; SMART: nucleotide binding protein, PINc; SPTR: twitching mobility protein PilT; PFAM: TRAM domain; PIN domain YP_004369747.1 COGs: COG1329 transcriptional regulators similar to M. xanthus CarD; InterPro IPR003711; KEGG: dbr:Deba_0731 CarD family transcriptional regulator; PFAM: transcription factor CarD; SPTR: CarD-like protein; PFAM: CarD-like/TRCF domain YP_004369748.1 COGs: COG1570 Exonuclease VII large subunit; HAMAP: Exonuclease VII, large subunit; InterPro IPR004365:IPR020579:IPR003753; KEGG: gsu:GSU1767 exodeoxyribonuclease VII large subunit; PFAM: Exonuclease VII, large subunit, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; SPTR: exodeoxyribonuclease 7 large subunit 2; TIGRFAM: Exonuclease VII, large subunit; PFAM: Exonuclease VII, large subunit; OB-fold nucleic acid binding domain; TIGRFAM: exodeoxyribonuclease VII, large subunit YP_004369749.1 HAMAP: Exonuclease VII, small subunit; InterPro IPR003761; KEGG: dal:Dalk_0838 exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII, small subunit; SPTR: exodeoxyribonuclease 7 small subunit; TIGRFAM: Exonuclease VII, small subunit; PFAM: Exonuclease VII small subunit; TIGRFAM: exodeoxyribonuclease VII, small subunit YP_004369750.1 COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: dak:DaAHT2_1032 geranyltranstransferase; PFAM: polyprenyl synthetase; PRIAM: farnesyltranstransferase; SPTR: Geranyltranstransferase; PFAM: polyprenyl synthetase YP_004369751.1 COGs: COG1154 Deoxyxylulose-5-phosphate synthase; HAMAP: Deoxyxylulose-5-phosphate synthase; InterPro IPR005475:IPR005476:IPR005477; KEGG: gsu:GSU0686 1-deoxy-D-xylulose-5-phosphate synthase; PFAM: transketolase-like, pyrimidine-binding domain; transketolase, C-terminal; PRIAM: 1-deoxy-D-xylulose-5-phosphate synthase; SMART: transketolase-like, pyrimidine-binding domain; SPTR: 1-deoxy-D-xylulose-5-phosphate synthase 1; TIGRFAM: Deoxyxylulose-5-phosphate synthase; PFAM: transketolase, C-terminal domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; transketolase, pyrimidine binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase YP_004369752.1 KEGG: amd:AMED_5474 cytochrome bd-I oxidase subunit I; SPTR: Cytochrome bd-I oxidase subunit I YP_004369753.1 KEGG: geo:Geob_3309 Cna B domain protein; SPTR: TonB-dependent receptor plug domain protein YP_004369754.1 KEGG: ppp:PHYPADRAFT_103781 hypothetical protein; SPTR: Predicted protein YP_004369755.1 COGs: COG1295 membrane protein; InterPro IPR004664:IPR017039; KEGG: gvi:gll4130 ribonuclease; PFAM: ribonuclease BN-related; SPTR: Probable ribonuclease; TIGRFAM: ribonuclease BN; PFAM: ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN) YP_004369756.1 COGs: COG2911 conserved hypothetical protein; InterPro IPR007452; KEGG: dbr:Deba_0840 protein of unknown function DUF490; PFAM: protein of unknown function DUF490; SPTR: uncharacterized protein; PFAM: Family of unknown function (DUF490) YP_004369757.1 KEGG: cbr:CBG20455 Hypothetical protein CBG20455; SPTR: uncharacterized protein YP_004369758.1 KEGG: dol:Dole_0381 hypothetical protein; SPTR: uncharacterized protein YP_004369759.1 InterPro IPR019300; KEGG: sfu:Sfum_1296 hypothetical protein; PFAM: RNA-binding protein, predicted; SPTR: uncharacterized protein; PFAM: Predicted RNA-binding protein YP_004369760.1 KEGG: tko:TK1158 endonuclease-methyltransferase fusion protein; SPTR: Predicted endonuclease-methyltransferase fusion protein; PFAM: N-6 DNA methylase YP_004369761.1 COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; KEGG: rme:Rmet_2960 dihydrodipicolinate synthase; SPTR: dihydrodipicolinate synthase YP_004369762.1 KEGG: glo:Glov_1229 cytochrome c class I; SPTR: Cytochrome c class I; PFAM: Cytochrome c YP_004369763.1 COGs: COG1751 conserved hypothetical protein; KEGG: tjr:TherJR_1556 protein of unknown function DUF1867; SPTR: uncharacterized protein; PFAM: pyruvate kinase, alpha/beta domain YP_004369764.1 COGs: COG0182 translation initiation factor 2B subunit eIF-2B alpha/beta/delta family; HAMAP: translation initiation factor, aIF-2BI/5-methylthioribose-1-phosphate isomerase; InterPro IPR000649:IPR005251:IPR011559; KEGG: gem:GM21_3753 translation initiation factor, aIF-2BI family; PFAM: Initiation factor 2B-related; PRIAM: S-methyl-5-thioribose-1-phosphate isomerase; SPTR: methylthioribose-1-phosphate isomerase; TIGRFAM: translation initiation factor, aIF-2BI/5-methylthioribose-1-phosphate isomerase; Initiation factor 2B alpha/beta/delta; PFAM: Initiation factor 2 subunit family; TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized proteins; S-methyl-5-thioribose-1-phosphate isomerase YP_004369765.1 COGs: COG1376 conserved hypothetical protein; InterPro IPR002482:IPR018392:IPR005490; KEGG: sfu:Sfum_0476 ErfK/YbiS/YcfS/YnhG family protein; PFAM: YkuD domain; peptidoglycan-binding lysin domain; SMART: peptidoglycan-binding Lysin subgroup; SPTR: ErfK/YbiS/YcfS/YnhG family protein; PFAM: L,D-transpeptidase catalytic domain YP_004369766.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: sfu:Sfum_0618 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain YP_004369767.1 COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR003661:IPR003594; KEGG: sfu:Sfum_0617 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004369768.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: dma:DMR_02030 hypothetical protein; PFAM: Cyclic nucleotide-binding domain; SMART: Cyclic nucleotide-binding domain; SPTR: uncharacterized protein; PFAM: Cyclic nucleotide-binding domain YP_004369769.1 InterPro IPR013099:IPR003148; KEGG: cts:Ctha_1299 ion transport 2 domain protein; PFAM: Ion transport 2; Regulator of K+ conductance, N-terminal; SPTR: Ion transport 2 domain protein; PFAM: Ion channel; TrkA-N domain YP_004369770.1 COGs: COG0461 Orotate phosphoribosyltransferase; InterPro IPR000836:IPR004467; KEGG: mtp:Mthe_1305 orotate phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Orotate phosphoribosyltransferase; SPTR: Orotate phosphoribosyltransferase; TIGRFAM: Orotate phosphoribosyl transferase, clade 1; PFAM: phosphoribosyl transferase domain; TIGRFAM: orotate phosphoribosyltransferase YP_004369771.1 InterPro IPR020942; KEGG: sfu:Sfum_4047 cytochrome c, class III; PFAM: Cytochrome c, class III domain; SPTR: Acidic cytochrome c3 family protein; PFAM: Class III cytochrome C family YP_004369772.1 COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: sfu:Sfum_0003 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase-related; SPTR: uncharacterized protein; TIGRFAM: queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein YP_004369773.1 KEGG: sat:SYN_01416 cytoplasmic protein; SPTR: Hypothetical cytosolic protein YP_004369774.1 KEGG: dbr:Deba_0422 hypothetical protein; SPTR: uncharacterized protein YP_004369775.1 COGs: COG0560 phosphoserine phosphatase; InterPro IPR006383:IPR006385; KEGG: nde:NIDE0243 haloacid dehalogenase superfamily hydrolase, subfamily IB, PSPase-like; SPTR: Haloacid dehalogenase superfamily hydrolase, subfamily IB, PSPase-like; TIGRFAM: HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial; HAD-superfamily hydrolase, subfamily IB, PSPase-like; TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like YP_004369776.1 COGs: COG0558 phosphatidylglycerophosphate synthase; InterPro IPR000462; KEGG: sti:Sthe_1445 CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_004369777.1 COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR003661:IPR003594:IPR004010; KEGG: dma:DMR_07770 sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Cache; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004369778.1 COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR003660:IPR000014:IPR003661:IPR003594:IPR 013767; KEGG: gme:Gmet_0777 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; HAMP linker domain; PAS; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: PAS domain S-box protein; TIGRFAM: PAS; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004369779.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: sat:SYN_02713 response regulator; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: Response regulator containing sigma 54 interaction domain; PFAM: Response regulator receiver domain; Sigma-54 interaction domain YP_004369780.1 KEGG: sfu:Sfum_0603 hypothetical protein; SPTR: uncharacterized protein YP_004369781.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: sta:STHERM_c05440 transcriptional regulatory protein; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: transcriptional regulatory protein; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004369782.1 KEGG: xcv:XCV2168 hypothetical protein; SPTR: uncharacterized protein YP_004369783.1 COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: mca:MCA1892 hypothetical protein; PFAM: ATPase, AAA-4; SPTR: uncharacterized protein; PFAM: Divergent AAA domain YP_004369784.1 COGs: COG0010 arginase/agmatinase/formimionoglutamate hydrolase arginase; InterPro IPR006035:IPR005925; KEGG: mgm:Mmc1_3564 agmatinase; PFAM: Ureohydrolase; PRIAM: Agmatinase; SPTR: agmatinase; TIGRFAM: agmatinase; PFAM: arginase; TIGRFAM: agmatinase YP_004369785.1 COGs: COG1899 Deoxyhypusine synthase; InterPro IPR002773; KEGG: nde:NIDE3977 deoxyhypusine synthase; PFAM: Deoxyhypusine synthase; PRIAM: Deoxyhypusine synthase; SPTR: Deoxyhypusine synthase; PFAM: Deoxyhypusine synthase; TIGRFAM: deoxyhypusine synthase YP_004369786.1 COGs: COG1225 Peroxiredoxin; InterPro IPR013740; KEGG: cch:Cag_2013 thiol:disulfide interchange protein, thioredoxin family protein; PFAM: Redoxin; SPTR: Thiol:disulfide interchange protein, thioredoxin family protein; PFAM: AhpC/TSA family YP_004369787.1 KEGG: dol:Dole_2855 TPR repeat-containing protein; SPTR: uncharacterized protein YP_004369788.1 COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: sti:Sthe_0912 protein of unknown function UPF0079; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family YP_004369789.1 COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR000644; KEGG: dak:DaAHT2_0243 hypothetical protein; PFAM: cystathionine beta-synthase, core; SMART: cystathionine beta-synthase, core; SPTR: CBS; PFAM: CBS domain YP_004369790.1 COGs: COG0063 sugar kinase; InterPro IPR004443:IPR000631; KEGG: ppd:Ppro_2259 carbohydrate kinase, YjeF related protein; PFAM: Uncharacterised protein family, carbohydrate kinase-related; YjeF-related protein, N-terminal; SPTR: Carbohydrate kinase, YjeF related protein; TIGRFAM: Uncharacterised protein family, carbohydrate kinase-related; YjeF-related protein, N-terminal; PFAM: Carbohydrate kinase; YjeF-related protein N-terminus; TIGRFAM: yjeF C-terminal region, hydroxyethylthiazole kinase-related; yjeF N-terminal region YP_004369792.1 KEGG: bfa:Bfae_07360 hypothetical protein; SPTR: uncharacterized protein YP_004369793.1 COGs: COG1150 Heterodisulfide reductase subunit C; KEGG: tye:THEYE_A1829 QmoC; SPTR: QmoC YP_004369794.1 COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR006076:IPR001450:IPR003813; KEGG: tye:THEYE_A1830 heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta; PFAM: methyl-viologen-reducing hydrogenase, delta subunit; FAD dependent oxidoreductase; 4Fe-4S binding domain; SPTR: Heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta; PFAM: methyl-viologen-reducing hydrogenase, delta subunit; Pyridine nucleotide-disulphide oxidoreductase YP_004369795.1 COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR003953:IPR001450; KEGG: tye:THEYE_A1831 CoB--CoM heterodisulfide reductase iron-sulfur subunit A 2; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; 4Fe-4S binding domain; SPTR: CoB--CoM heterodisulfide reductase iron-sulfur subunit A 2; PFAM: FAD binding domain YP_004369796.1 COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR011803; KEGG: cte:CT0865 adenylylsulfate reductase subunit alpha; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; SPTR: AprA; TIGRFAM: adenylylsulphate reductase, alpha subunit; PFAM: domain; FAD binding domain; TIGRFAM: adenosine phosphosulphate reductase, alpha subunit YP_004369797.1 InterPro IPR001450:IPR011802; KEGG: cte:CT0864 adenylylsulfate reductase, beta subunit; PFAM: 4Fe-4S binding domain; SPTR: AprB; TIGRFAM: adenylylsulphate reductase, beta subunit; PFAM: adenosine-5'-phosphosulfate reductase beta subunit; TIGRFAM: adenosine phosphosulphate reductase, beta subunit YP_004369798.1 COGs: COG2046 ATP sulfurylase (sulfate adenylyltransferase); HAMAP: Sulphate adenylyltransferase, subgroup; InterPro IPR002650:IPR020792; KEGG: cte:CT0862 sulfate adenylyltransferase; PFAM: Sulphate adenylyltransferase; PRIAM: sulfate adenylyltransferase; SPTR: sulfate adenylyltransferase; TIGRFAM: Sulphate adenylyltransferase; PFAM: ATP-sulfurylase; TIGRFAM: ATP sulphurylase YP_004369799.1 COGs: COG1350 alternative tryptophan synthase beta-subunit (paralog of TrpB); HAMAP: Tryptophan synthase beta chain/beta chain-like; InterPro IPR001926:IPR023026:IPR006316; KEGG: ank:AnaeK_3805 tryptophan synthase subunit beta; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Tryptophan synthase; SPTR: Tryptophan synthase beta chain 1; TIGRFAM: Tryptophan synthase, beta chain-like; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: pyridoxal-phosphate dependent TrpB-like enzyme YP_004369800.1 COGs: COG1371 conserved hypothetical protein; InterPro IPR002804; KEGG: tye:THEYE_A1749 hypothetical protein; PFAM: Archease, tRNA m5C methyltransferase chaperone; SPTR: uncharacterized protein; PFAM: Archease (DUF101/UPF0211) YP_004369801.1 COGs: COG1690 conserved hypothetical protein; InterPro IPR001233; KEGG: pca:Pcar_0019 hypothetical protein; PFAM: Uncharacterised protein family UPF0027; SPTR: uncharacterized protein; PFAM: Uncharacterized protein family UPF0027 YP_004369802.1 COGs: COG0541 Signal recognition particle GTPase; InterProIPR013822:IPR003593:IPR000897:IPR004125:IPR 004780; KEGG: dbr:Deba_3169 signal recognition particle protein; PFAM: Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, helical bundle; Signal recognition particle, SRP54 subunit, M-domain; SMART: Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, helical bundle; ATPase, AAA+ type, core; SPTR: Signal recognition particle protein; TIGRFAM: Signal recognition particle, SRP; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; Signal peptide binding domain; TIGRFAM: signal recognition particle protein YP_004369803.1 COGs: COG0228 ribosomal protein S16; HAMAP: ribosomal protein S16; InterPro IPR000307; KEGG: dps:DP2800 30S ribosomal protein S16; PFAM: ribosomal protein S16; SPTR: 30S ribosomal protein S16; TIGRFAM: ribosomal protein S16; PFAM: ribosomal protein S16; TIGRFAM: ribosomal protein S16 YP_004369804.1 COGs: COG1837 RNA-binding protein (contains KH domain); HAMAP: Uncharacterised protein family UPF0109, bacterial; InterPro IPR020627; KEGG: dbr:Deba_3167 hypothetical protein; SPTR: uncharacterized protein YP_004369805.1 COGs: COG0806 RimM protein required for 16S rRNA processing; HAMAP: 16S rRNA processing protein RimM; InterPro IPR002676:IPR007903:IPR011961; KEGG: glo:Glov_2452 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel; SPTR: 16S rRNA processing protein RimM; TIGRFAM: 16S rRNA processing protein RimM; PFAM: RimM N-terminal domain; TIGRFAM: 16S rRNA processing protein RimM YP_004369806.1 COGs: COG0336 tRNA-(guanine-N1)-methyltransferase; HAMAP: tRNA (guanine-N1-)-methyltransferase, bacteria; InterPro IPR016009:IPR002649; KEGG: gur:Gura_3760 tRNA (guanine-N(1)-)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase; PRIAM: tRNA (guanine-N(1)-)-methyltransferase; SPTR: tRNA (guanine-N(1)-)-methyltransferase; TIGRFAM: tRNA (guanine-N1-)-methyltransferase, bacteria; PFAM: tRNA (Guanine-1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase YP_004369807.1 COGs: COG0335 ribosomal protein L19; HAMAP: ribosomal protein L19; InterPro IPR001857; KEGG: sat:SYN_00770 50S ribosomal protein L19; PFAM: ribosomal protein L19; SPTR: 50S ribosomal protein L19; TIGRFAM: ribosomal protein L19; PFAM: ribosomal protein L19; TIGRFAM: ribosomal protein L19, bacterial type YP_004369808.1 COGs: COG0164 ribonuclease HII; InterPro IPR001352; KEGG: tte:TTE1451 ribonuclease HII; PFAM: ribonuclease HII/HIII; PRIAM: ribonuclease H; SPTR: ribonuclease HII; PFAM: ribonuclease HII YP_004369809.1 COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; HAMAP: Uncharacterised protein family UPF0102; InterPro IPR003509; KEGG: dak:DaAHT2_1166 protein of unknown function UPF0102; PFAM: Uncharacterised protein family UPF0102; SPTR: UPF0102 protein DaAHT2_1166; TIGRFAM: Uncharacterised protein family UPF0102; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein YP_004369810.1 COGs: COG0313 methyltransferase; HAMAP: ribosomal RNA small subunit methyltransferase I; InterPro IPR000878:IPR008189; KEGG: gem:GM21_3481 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; TIGRFAM: Uncharacterised protein family UPF0011; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: probable S-adenosylmethionine-dependent methyltransferase, YraL family YP_004369811.1 COGs: COG1925 phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: drt:Dret_2016 phosphotransferase system, phosphocarrier protein HPr; PFAM: phosphotransferase system, phosphocarrier HPr protein; SPTR: phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphotransferase system, phosphocarrier HPr protein; PFAM: PTS HPr component phosphorylation site; TIGRFAM: phosphotransferase System HPr (HPr) Family YP_004369812.1 COGs: COG1080 phosphoenolpyruvate-protein kinase (PTS system EI component); InterPro IPR008731:IPR008279:IPR000121:IPR006318; KEGG: dbr:Deba_3160 phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilising enzyme; PEP-utilising enzyme, mobile domain; phosphotransferase system, PEP-utilising enzyme, N-terminal; PRIAM: phosphoenolpyruvate--protein phosphotransferase; SPTR: phosphoenolpyruvate-protein phosphotransferase; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase YP_004369813.1 COGs: COG0691 tmRNA-binding protein; HAMAP: SsrA-binding protein; InterPro IPR000037; KEGG: gwc:GWCH70_2954 SsrA-binding protein; PFAM: SsrA-binding protein; SPTR: SsrA-binding protein; TIGRFAM: SsrA-binding protein; PFAM: SmpB protein; TIGRFAM: SsrA-binding protein YP_004369814.1 COGs: COG4889 helicase; InterPro IPR003356; KEGG: ttr:Tter_1765 hypothetical protein; PFAM: DNA methylase, adenine-specific; SPTR: DNA methyltransferase/helicase; PFAM: N-6 DNA methylase YP_004369815.1 InterPro IPR005358; KEGG: tye:THEYE_A0135 lipoprotein, PFAM: Uncharacterised protein family UPF0153; SPTR: Lipoprotein, ; PFAM: Uncharacterised protein family (UPF0153) YP_004369816.1 COGs: COG0591 Na+/proline symporter; InterProIPR003018:IPR000014:IPR001610:IPR003661:IPR 003594:IPR001734:IPR013767; KEGG: geo:Geob_2606 protein serine phosphatase with GAF(s) sensor(s); PFAM: ATPase-like, ATP-binding domain; GAF; Sodium/solute symporter; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; GAF; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: phytochrome sensor protein; TIGRFAM: PAS; PFAM: GAF domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004369817.1 KEGG: ddf:DEFDS_1670 hypothetical protein; SPTR: uncharacterized protein YP_004369818.1 KEGG: bph:Bphy_1237 periplasmic binding protein/LacI transcriptional regulator; SPTR: uncharacterized protein YP_004369819.1 COGs: COG1167 transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: pmo:Pmob_1584 GntR family transcriptional regulator; PFAM: Aminotransferase, class I/classII; PRIAM: Aromatic-amino-acid transaminase; SPTR: GntR family transcriptional regulator; PFAM: Aminotransferase class I and II YP_004369820.1 InterPro IPR002716; KEGG: dau:Daud_0408 twitching mobility protein PilT; PFAM: PilT protein, N-terminal; SPTR: twitching mobility protein PilT; PFAM: PIN domain YP_004369821.1 InterPro IPR007159:IPR006339; KEGG: dau:Daud_0407 AbrB family transcriptional regulator; PFAM: transcription regulator AbrB/SpoV, predicted; SMART: transcription regulator AbrB/SpoV, predicted; SPTR: AbrB family transcriptional regulator; TIGRFAM: transcription regulator AbrB; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family YP_004369822.1 COGs: COG0385 Na+-dependent transporter; InterPro IPR002657; KEGG: aba:Acid345_1377 bile acid/sodium symporter; PFAM: Bile acid:sodium symporter; SPTR: Bile acid/sodium symporter; PFAM: Sodium Bile acid symporter family YP_004369823.1 InterPro IPR001450; KEGG: mhu:Mhun_1694 iron-sulfur cluster binding protein; PFAM: 4Fe-4S binding domain; SPTR: Iron-sulfur cluster binding protein YP_004369824.1 COGs: COG1679 conserved hypothetical protein; InterPro IPR002840:IPR007506; KEGG: mhu:Mhun_1693 hypothetical protein; PFAM: Domain of unknown function DUF521; Domain of unknown function DUF126; SPTR: Predicted aconitase subunit 2 / predicted aconitase subunit 1; PFAM: protein of unknown function DUF126; protein of unknown function (DUF521) YP_004369825.1 COGs: COG3829 transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterPro IPR003593:IPR002078:IPR002197; KEGG: dol:Dole_1257 sigma54 specific transcriptional regulator; PFAM: RNA polymerase sigma factor 54, interaction; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; SPTR: sigma54 specific transcriptional regulator; PFAM: Sigma-54 interaction domain YP_004369826.1 InterPro IPR008815; KEGG: gca:Galf_0430 S23 ribosomal protein; PFAM: 23S rRNA-associated protein; SPTR: S23 ribosomal protein; PFAM: S23 ribosomal protein YP_004369827.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: pfo:Pfl01_1974 lytic transglycosylase, catalytic; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Lytic transglycosylase, catalytic; PFAM: transglycosylase SLT domain YP_004369828.1 SPTR: uncharacterized protein YP_004369829.1 COGs: COG5563 integral membrane protein containing uncharacterized repeats; InterPro IPR011449:IPR014262; KEGG: bvi:Bcep1808_6998 autotransporter beta-domain-containing protein; PFAM: PEP-CTERM bacterial; SPTR: Probable extracellular repeat, HAF family; TIGRFAM: Extracellular HAF; TIGRFAM: probable extracellular repeat, HAF family YP_004369830.1 KEGG: pin:Ping_1185 hypothetical protein; SPTR: uncharacterized protein YP_004369831.1 KEGG: dba:Dbac_2544 hypothetical protein; SPTR: uncharacterized protein YP_004369832.1 KEGG: cyj:Cyan7822_3049 hemolysin-type calcium-binding region; SPTR: uncharacterized protein; TIGRFAM: variant PEP-CTERM exosortase signal, Roseobacter type YP_004369833.1 InterPro IPR009894; KEGG: dat:HRM2_25520 hypothetical protein; PFAM: Exported; SPTR: Predicted protein YP_004369834.1 KEGG: mxa:MXAN_6573 lipoprotein; SPTR: uncharacterized protein YP_004369835.1 KEGG: fri:FraEuI1c_1167 PAS/PAC sensor protein; SPTR: uncharacterized protein YP_004369836.1 KEGG: bfs:BF1582 hypothetical protein; SPTR: uncharacterized protein YP_004369837.1 InterPro IPR003367; KEGG: sth:STH1184 hypothetical protein; PFAM: Thrombospondin, type 3-like repeat; SPTR: uncharacterized protein YP_004369838.1 KEGG: tgr:Tgr7_2296 protein of unknown function DUF1555; SPTR: uncharacterized protein YP_004369839.1 KEGG: vcn:VOLCADRAFT_91066 hypothetical protein; SPTR: uncharacterized protein YP_004369840.1 KEGG: dal:Dalk_3698 protein of unknown function DUF1573; SPTR: uncharacterized protein YP_004369841.1 KEGG: smd:Smed_5128 hypothetical protein; SPTR: uncharacterized protein YP_004369842.1 KEGG: afw:Anae109_3962 hypothetical protein; SPTR: uncharacterized protein YP_004369843.1 COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR019734:IPR001440; KEGG: ank:AnaeK_2910 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide repeat protein; PFAM: Tetratricopeptide repeat YP_004369844.1 COGs: COG2064 Flp pilus assembly protein TadC; InterPro IPR018076; KEGG: cti:RALTA_A0688 Tad secretion system, secretion accessory protein; PFAM: Type II secretion system F domain; SPTR: Tad secretion system, secretion accessory protein; PFAM: Bacterial type II secretion system protein F domain YP_004369845.1 COGs: COG4965 Flp pilus assembly protein TadB; InterPro IPR018076; KEGG: bpy:Bphyt_4618 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: Type II secretion system protein; PFAM: Bacterial type II secretion system protein F domain YP_004369846.1 COGs: COG4962 Flp pilus assembly protein ATPase CpaF; InterPro IPR001482; KEGG: mmb:Mmol_1394 type II secretion system protein E; PFAM: Type II secretion system protein E; SPTR: Type II secretion system protein E; PFAM: Type II/IV secretion system protein YP_004369847.1 COGs: COG4963 Flp pilus assembly protein ATPase CpaE; KEGG: ank:AnaeK_2914 Flp pilus assembly protein ATPase CpaE-like protein; SPTR: Flp pilus assembly protein ATPase CpaE-like protein; PFAM: Response regulator receiver domain; CobQ/CobB/MinD/ParA nucleotide binding domain YP_004369848.1 COGs: COG4964 Flp pilus assembly protein secretin CpaC; InterPro IPR004846; KEGG: acp:A2cp1_3007 type II and III secretion system protein; PFAM: Type II/III secretion system; SPTR: Type II and III secretion system protein; PFAM: Bacterial type II and III secretion system protein YP_004369849.1 COGs: COG3745 Flp pilus assembly protein CpaB; KEGG: dbr:Deba_1990 Flp pilus assembly protein CpaB; SPTR: Flp pilus assembly protein CpaB; TIGRFAM: Flp pilus assembly protein CpaB YP_004369850.1 InterPro IPR012495; KEGG: ank:AnaeK_2917 TadE family protein; PFAM: TadE-like; SPTR: TadE family protein; PFAM: TadE-like protein YP_004369851.1 COGs: COG4960 Flp pilus assembly protein protease CpaA; InterPro IPR000045; KEGG: cti:RALTA_A0699 prepilin peptidase transmembrane protein; PFAM: peptidase A24A, prepilin type IV; SPTR: prepilin peptIDASE transMEMBRANE protein; PFAM: Type IV leader peptidase YP_004369852.1 InterPro IPR007047; KEGG: axy:AXYL_04455 Flp/Fap pilin component family protein; PFAM: Flp/Fap pilin component; SPTR: uncharacterized protein; PFAM: Flp/Fap pilin component YP_004369853.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000595:IPR018060:IPR000005; KEGG: ote:Oter_4074 AraC family transcriptional regulator; PFAM: Cyclic nucleotide-binding domain; HTH transcriptional regulator, AraC; SMART: Helix-turn-helix, AraC type, DNA binding domain; Cyclic nucleotide-binding domain; SPTR: AraC family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; Cyclic nucleotide-binding domain YP_004369854.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: mxa:MXAN_4628 transglycosylase SLT domain-containing protein; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Lytic transglycosylase, catalytic; PFAM: transglycosylase SLT domain YP_004369855.1 COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR003593:IPR007831:IPR001482:IPR013369; KEGG: dat:HRM2_30260 GspE3; PFAM: Type II secretion system protein E; General secretory system II, protein E, N-terminal; SMART: ATPase, AAA+ type, core; SPTR: General secretion pathway protein E (Type II traffic warden ATPase); TIGRFAM: Type II secretion system GspE; PFAM: GSPII_E N-terminal domain; Type II/IV secretion system protein; TIGRFAM: general secretory pathway protein E YP_004369856.1 COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076; KEGG: dat:HRM2_30250 GspF2; PFAM: Type II secretion system F domain; SPTR: General secretion pathway protein F; PFAM: Bacterial type II secretion system protein F domain YP_004369857.1 COGs: COG2165 Type II secretory pathway pseudopilin PulG; InterPro IPR012902:IPR013545:IPR010054; KEGG: sfu:Sfum_0102 general secretion pathway protein G; PFAM: Type II secretion system protein G; prepilin-type cleavage/methylation, N-terminal; SPTR: General secretion pathway protein G; TIGRFAM: General secretion pathway protein G; prepilin-type cleavage/methylation, N-terminal; PFAM: Prokaryotic N-terminal methylation motif; Bacterial type II secretion system protein G; TIGRFAM: general secretion pathway protein G; prepilin-type N-terminal cleavage/methylation domain YP_004369858.1 COGs: COG4970 Tfp pilus assembly protein FimT; InterPro IPR012902; KEGG: vei:Veis_0685 general secretion pathway protein H; SPTR: General secretion pathway protein H; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004369859.1 InterPro IPR012902; KEGG: nhl:Nhal_0443 general secretion pathway protein H; SPTR: General secretion pathway protein H YP_004369860.1 InterPro IPR012902; KEGG: mca:MCA1119 general secretory pathway protein J; SPTR: prepilin-type N-terminal cleavage/methylation domain protein YP_004369861.1 COGs: COG3156 Type II secretory pathway component PulK; InterPro IPR005628; KEGG: geo:Geob_0889 general secretion pathway protein K; SPTR: General secretion pathway protein K; PFAM: General secretion pathway protein K YP_004369862.1 InterPro IPR007813; KEGG: dat:HRM2_30140 GspL; PFAM: Fimbrial assembly; SPTR: GspL; PFAM: Fimbrial assembly protein (PilN) YP_004369863.1 KEGG: pfh:PFHG_04978 conserved hypothetical protein; SPTR: uncharacterized protein YP_004369864.1 KEGG: sfu:Sfum_3667 hypothetical protein; SPTR: uncharacterized protein YP_004369865.1 COGs: COG1450 Type II secretory pathway component PulD; InterPro IPR005644:IPR004846:IPR013356; KEGG: mca:MCA1123 general secretion pathway protein D; PFAM: Type II/III secretion system; NolW-like; SPTR: General secretion pathway protein D; TIGRFAM: Type II secretion system GspD; PFAM: Bacterial type II/III secretion system short domain; Bacterial type II and III secretion system protein; TIGRFAM: general secretion pathway protein D YP_004369866.1 KEGG: rcu:RCOM_1951500 hypothetical protein; SPTR: uncharacterized protein YP_004369867.1 COGs: COG1989 Type II secretory pathway prepilin signal peptidase PulO and related peptidase; InterPro IPR010627:IPR000045; KEGG: dps:DP3017 type IV prepilin leader peptidase; PFAM: peptidase A24A, N-terminal; peptidase A24A, prepilin type IV; PRIAM: prepilin peptidase; SPTR: prepilin peptidase; PFAM: Bacterial peptidase A24 N-terminal domain; Type IV leader peptidase YP_004369868.1 KEGG: cyn:Cyan7425_3828 mannose-6-phosphate isomerase; SPTR: chloride channel YP_004369869.1 KEGG: dma:DMR_45170 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1640) YP_004369870.1 COGs: COG0595 hydrolase of the metallo-beta-lactamase superfamily; InterPro IPR001279:IPR011108:IPR004613; KEGG: gur:Gura_4393 beta-lactamase domain-containing protein; PFAM: Beta-lactamase-like; RNA-metabolising metallo-beta-lactamase; SMART: Beta-lactamase-like; SPTR: Beta-lactamase domain protein; TIGRFAM: ribonuclease J; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; TIGRFAM: conserved hypothetical protein YP_004369871.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123:IPR004552; KEGG: sfu:Sfum_1596 1-acyl-sn-glycerol-3-phosphate acyltransferases; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_004369872.1 KEGG: mar:MAE_21550 Na-Ca exchanger/integrin-beta; SPTR: Na-Ca exchanger/integrin-beta YP_004369873.1 KEGG: bpe:BP2527 secretory protein; SPTR: secretory protein YP_004369874.1 KEGG: nde:NIDE3865 hypothetical protein; SPTR: uncharacterized protein YP_004369875.1 InterPro IPR000835; KEGG: tjr:TherJR_0519 transcriptional regulator, MarR family; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: transcriptional regulator, MarR family; PFAM: MarR family YP_004369876.1 COGs: COG0247 Fe-S oxidoreductase; Contains selenocysteine; InterPro IPR004017; KEGG: dps:DP1009 Fe-S oxidoreductase; PFAM: cysteine-rich domain; SPTR: Probable Fe-S oxidoreductase; manually curated; PFAM: cysteine-rich domain YP_004369877.1 COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR001327:IPR001450:IPR003813; KEGG: dal:Dalk_2777 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase, delta subunit; 4Fe-4S binding domain; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; SPTR: methyl-viologen-reducing hydrogenase delta subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; methyl-viologen-reducing hydrogenase, delta subunit YP_004369878.1 COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR006076; KEGG: dal:Dalk_2778 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: FAD dependent oxidoreductase; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004369879.1 COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: dal:Dalk_2561 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase YP_004369880.1 KEGG: dal:Dalk_2780 hypothetical protein; SPTR: uncharacterized protein; PFAM: methylene-tetrahydrofolate reductase C terminal YP_004369881.1 COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: mta:Moth_1193 methyl-viologen-reducing hydrogenase, delta subunit; PFAM: methyl-viologen-reducing hydrogenase, delta subunit; SPTR: F420-non-reducing hydrogenase vhu iron-sulfur subunit D; PFAM: methyl-viologen-reducing hydrogenase, delta subunit YP_004369882.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR006076:IPR001450:IPR013027:IPR003953; KEGG: dbr:Deba_2226 FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; 4Fe-4S binding domain; Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; PRIAM: glutamate synthase (NADPH); SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; FAD binding domain; FAD dependent oxidoreductase YP_004369883.1 COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: sfu:Sfum_1805 hypothetical protein; PFAM: cysteine-rich domain; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: uncharacterized protein; PFAM: cysteine-rich domain YP_004369884.1 COGs: COG1150 Heterodisulfide reductase subunit C; KEGG: sfu:Sfum_1806 heterodisulfide reductase, C subunit; SPTR: Heterodisulfide reductase, C subunit YP_004369885.1 COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017; KEGG: dbr:Deba_2137 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: cysteine-rich domain; SPTR: uncharacterized protein; PFAM: cysteine-rich domain YP_004369886.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: dal:Dalk_2950 two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: fused DNA-binding response regulator in two-component regulatory system with ZraS: response regulator/sigma54 interaction protein; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004369887.1 COGs: COG5002 Signal transduction histidine kinase; InterPro IPR001789:IPR003661:IPR003594:IPR013767; KEGG: dal:Dalk_2419 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; SPTR: PAS domain S-box protein; PFAM: Response regulator receiver domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold YP_004369888.1 KEGG: dbr:Deba_2156 hypothetical protein; SPTR: uncharacterized protein YP_004369889.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: dbr:Deba_2154 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver domain protein; PFAM: Response regulator receiver domain YP_004369890.1 COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: sfu:Sfum_3130 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase YP_004369891.1 KEGG: sfu:Sfum_3131 hypothetical protein; SPTR: uncharacterized protein; PFAM: methylene-tetrahydrofolate reductase C terminal YP_004369892.1 COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: mta:Moth_1193 methyl-viologen-reducing hydrogenase, delta subunit; PFAM: methyl-viologen-reducing hydrogenase, delta subunit; SPTR: methyl-viologen-reducing hydrogenase, delta subunit; PFAM: methyl-viologen-reducing hydrogenase, delta subunit YP_004369893.1 COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR003953:IPR001450; KEGG: sfu:Sfum_3133 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; FAD binding domain YP_004369894.1 COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: sfu:Sfum_3014 methyl-viologen-reducing hydrogenase, delta subunit; PFAM: methyl-viologen-reducing hydrogenase, delta subunit; SPTR: methyl-viologen-reducing hydrogenase, delta subunit; PFAM: methyl-viologen-reducing hydrogenase, delta subunit YP_004369895.1 COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR002218:IPR001450:IPR003953; KEGG: sfu:Sfum_1977 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; 4Fe-4S binding domain; glucose-inhibited division protein A-related; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; PFAM: FAD binding domain; 4Fe-4S binding domain; glucose inhibited division protein A YP_004369896.1 COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: dal:Dalk_3267 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: uncharacterized protein; PFAM: methylenetetrahydrofolate reductase YP_004369897.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bse:Bsel_1485 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain YP_004369898.1 InterPro IPR002641; KEGG: nmu:Nmul_A1399 patatin; PFAM: patatin/phospholipase A2-related; SPTR: patatin; PFAM: patatin-like phospholipase YP_004369899.1 KEGG: dak:DaAHT2_2470 hypothetical protein; SPTR: uncharacterized protein YP_004369900.1 COGs: COG0194 Guanylate kinase; HAMAP: Guanylate kinase, sub-group; InterPro IPR008145:IPR008144:IPR017665; KEGG: dbr:Deba_2076 guanylate kinase; PFAM: Guanylate kinase; PRIAM: Guanylate kinase; SMART: Guanylate kinase/L-type calcium channel; SPTR: Guanylate kinase; TIGRFAM: Guanylate kinase, sub-group; PFAM: Guanylate kinase; TIGRFAM: guanylate kinase YP_004369901.1 COGs: COG2052 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0296; InterPro IPR007169; KEGG: dat:HRM2_18450 hypothetical protein; PFAM: Uncharacterised protein family UPF0296; SPTR: UPF0296 protein HRM2_18450; PFAM: Domain of unknown function (DUF370) YP_004369902.1 COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR013527:IPR013551:IPR005229; KEGG: sth:STH1337 hypothetical protein; PFAM: YicC-like, N-terminal; Domain of unknown function DUF1732; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00255; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: TIGR00255 family protein YP_004369903.1 KEGG: dol:Dole_1913 GTP-binding protein; SPTR: Conserved hypothetical GTP-binding protein YP_004369904.1 COGs: COG1270 Cobalamin biosynthesis protein CobD/CbiB; HAMAP: Cobalamin biosynthesis CobD/CbiB; InterPro IPR004485; KEGG: xne:XNC1_1150 cobalamin biosynthesis protein CbiB; PFAM: Cobalamin biosynthesis CobD/CbiB; SPTR: Cobalamin biosynthesis protein cbiB; TIGRFAM: Cobalamin biosynthesis CobD/CbiB; PFAM: CobD/Cbib protein; TIGRFAM: cobalamin biosynthesis protein CobD YP_004369905.1 COGs: COG0079 histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839:IPR005860; KEGG: mta:Moth_1104 L-threonine O-3-phosphate decarboxylase; PFAM: Aminotransferase, class I/classII; SPTR: L-threonine O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase YP_004369906.1 COGs: COG0357 S-adenosylmethionine-dependent methyltransferase involved in cell division; HAMAP: rRNA small subunit methyltransferase G; InterPro IPR003682; KEGG: mxa:MXAN_7493 methyltransferase GidB; PFAM: rRNA small subunit methyltransferase G; SPTR: ribosomal RNA small subunit methyltransferase G; TIGRFAM: rRNA small subunit methyltransferase G; PFAM: rRNA small subunit methyltransferase G; TIGRFAM: 16S rRNA (guanine(527)-N(7))-methyltransferase GidB YP_004369907.1 COGs: COG0486 GTPase; HAMAP: tRNA modification GTPase TrmE; InterPro IPR018948:IPR002917:IPR004520:IPR005225; KEGG: toc:Toce_2280 tRNA modification GTPase TrmE; PFAM: GTP-binding protein TrmE, N-terminal; GTP-binding protein, HSR1-related; SPTR: tRNA modification GTPase mnmE; TIGRFAM: tRNA modification GTPase TrmE; Small GTP-binding protein; PFAM: GTPase of unknown function; GTP-binding protein TrmE N-terminus; TIGRFAM: tRNA modification GTPase TrmE; small GTP-binding protein domain YP_004369908.1 COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: sfu:Sfum_2598 single-stranded nucleic acid binding R3H domain-containing protein; PFAM: Single-stranded nucleic acid binding R3H; SMART: Single-stranded nucleic acid binding R3H; SPTR: R3H domain protein; PFAM: R3H domain YP_004369909.1 COGs: COG0706 Preprotein translocase subunit YidC; HAMAP: Membrane insertion protein, OxaA/YidC, bacterial; InterPro IPR001708:IPR019998; KEGG: sat:SYN_01014 60 kDa inner membrane protein; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Inner membrane protein oxaA; TIGRFAM: Membrane insertion protein, OxaA/YidC; Membrane insertion protein, OxaA/YidC, bacterial; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain; membrane protein insertase, YidC/Oxa1 family, N-terminal domain YP_004369910.1 COGs: COG0759 conserved hypothetical protein; HAMAP: protein of unknown function DUF37; InterPro IPR002696; KEGG: elm:ELI_4600 hypothetical protein; PFAM: protein of unknown function DUF37; SPTR: UPF0161 protein BBR47_59460; TIGRFAM: protein of unknown function DUF37; PFAM: Domain of unknown function DUF37; TIGRFAM: conserved hypothetical protein YidD YP_004369911.1 COGs: COG0594 RNase P protein component; HAMAP: ribonuclease P; InterPro IPR000100; KEGG: sat:SYN_01012 ribonuclease P protein component; PFAM: ribonuclease P; SPTR: ribonuclease P protein component; TIGRFAM: ribonuclease P; manually curated; PFAM: ribonuclease P; TIGRFAM: ribonuclease P protein component, eubacterial YP_004369912.1 HAMAP: ribosomal protein L34; InterPro IPR000271; KEGG: hha:Hhal_1228 ribosomal protein L34; PFAM: ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: ribosomal protein L34; manually curated; PFAM: ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type YP_004369913.1 COGs: COG0621 2-methylthioadenine synthetase; HAMAP: tRNA-i(6)A37 modification enzyme MiaB; InterProIPR006638:IPR013848:IPR007197:IPR002792:IPR 006463:IPR005839; KEGG: sat:SYN_02149 tRNA 2-methylthioadenosine synthase; PFAM: methylthiotransferase, N-terminal; Radical SAM; Deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: (Dimethylallyl)adenosine tRNA methylthiotransferase miaB; TIGRFAM: tRNA-i(6)A37 modification enzyme MiaB; methylthiotransferase; PFAM: TRAM domain; Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB; radical SAM methylthiotransferase, MiaB/RimO family YP_004369914.1 COGs: COG1259 conserved hypothetical protein; InterPro IPR003729; KEGG: sfu:Sfum_0418 hypothetical protein; PFAM: Domain of unknown function DUF151; SPTR: uncharacterized protein; PFAM: Uncharacterised ACR, COG1259 YP_004369915.1 COGs: COG1387 histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR003141:IPR004013; KEGG: dak:DaAHT2_0804 PHP domain protein; PFAM: PHP, C-terminal; SMART: polymerase/histidinol phosphatase, N-terminal; SPTR: PHP domain protein; PFAM: PHP domain YP_004369916.1 COGs: COG0251 translation initiation inhibitor yjgF family; InterPro IPR006175:IPR006056; KEGG: rrs:RoseRS_2960 endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; SPTR: Endoribonuclease L-PSP; TIGRFAM: YjgF-like protein; PFAM: Endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP YP_004369917.1 COGs: COG2043 conserved hypothetical protein; InterPro IPR003748; KEGG: sfu:Sfum_1141 hypothetical protein; PFAM: protein of unknown function DUF169; SPTR: uncharacterized protein; PFAM: Uncharacterised ArCR, COG2043 YP_004369918.1 KEGG: pth:PTH_1016 succinate dehydrogenase/fumarate reductase, cytochrome b subunit; SPTR: Succinate dehydrogenase/fumarate reductase, cytochrome b subunit; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit YP_004369919.1 COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR004112:IPR014006; KEGG: pth:PTH_1017 fumarate reductase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: Succinate dehydrogenase; SPTR: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunitGram-negative/mitochondrial subgroup YP_004369920.1 COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR004489; KEGG: pth:PTH_1018 fumarate reductase iron-sulfur subunit; PRIAM: Succinate dehydrogenase; SPTR: Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein YP_004369921.1 KEGG: dak:DaAHT2_2463 transposase; SPTR: transposase YP_004369922.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: dat:HRM2_14290 two component transcriptional regulator (LuxR family protein); PFAM: Signal transduction response regulator, receiver domain; transcription regulator LuxR, C-terminal; SMART: transcription regulator LuxR, C-terminal; Signal transduction response regulator, receiver domain; SPTR: Two component transcriptional regulator (LuxR family protein); PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004369923.1 COGs: COG4585 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003594:IPR013656:IPR 013655:IPR013767:IPR011712; KEGG: nde:NIDE0578 hypothetical protein; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; PAS fold-4; PAS fold; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; PAS; PAC motif; SPTR: uncharacterized protein; TIGRFAM: PAS; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box YP_004369924.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834:IPR006402; KEGG: cpb:Cphamn1_1570 HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004369925.1 COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; HAMAP: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; InterPro IPR001986:IPR005750; KEGG: pca:Pcar_2690 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: Enolpyruvate transferase domain; PRIAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; SPTR: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_004369926.1 COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: pth:PTH_0458 ABC-type branched-chain amino acid transport systems, periplasmic component; PFAM: Extracellular ligand-binding receptor; SPTR: ABC-type branched-chain amino acid transport systems, periplasmic component; PFAM: Receptor family ligand binding region YP_004369927.1 COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: tye:THEYE_A0767 branched-chain amino acid ABC transporter, permease; PFAM: ABC transporter permease; SPTR: Branched-chain amino acid ABC transporter, permease; PFAM: Branched-chain amino acid transport system / permease component YP_004369928.1 COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: mag:amb2603 ABC-type branched-chain amino acid transport system; PFAM: ABC transporter permease; SPTR: ABC-type branched-chain amino acid transport system; PFAM: Branched-chain amino acid transport system / permease component YP_004369929.1 COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: mno:Mnod_1101 ABC transporter related; PFAM: ABC transporter-like; PRIAM: iron ABC transporter ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter YP_004369930.1 COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: bmr:BMI_II392 branched-chain amino acid ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: High-affinity branched-chain amino acid transport ATP-binding protein livf; PFAM: ABC transporter YP_004369931.1 COGs: COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: gme:Gmet_1272 virulence factor MCE-like protein-related protein; PFAM: Mammalian cell entry-related; SPTR: Mammalian cell entry-related protein; PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_004369932.1 KEGG: gem:GM21_1506 hypothetical protein; SPTR: uncharacterized protein YP_004369933.1 KEGG: bts:Btus_2973 transposase IS4 family protein; SPTR: transposase IS4 family protein YP_004369934.1 COGs: COG2932 transcriptional regulator protein; InterPro IPR001387:IPR019759; KEGG: dbr:Deba_0107 phage repressor; PFAM: peptidase S24/S26A/S26B, conserved region; Helix-turn-helix type 3; SPTR: phage repressor; PFAM: Helix-turn-helix; peptidase S24-like YP_004369935.1 KEGG: sus:Acid_1959 hypothetical protein; SPTR: uncharacterized protein YP_004369936.1 KEGG: pic:PICST_56965 hypothetical protein; SPTR: Predicted protein YP_004369937.1 COGs: COG1401 GTPase subunit of restriction endonuclease; InterPro IPR003593:IPR011704; KEGG: mpd:MCP_0968 hypothetical protein; PFAM: ATPase, AAA-5; SMART: ATPase, AAA+ type, core; SPTR: uncharacterized protein; PFAM: AAA domain (dynein-related subfamily) YP_004369938.1 COGs: COG4268 McrBC 5-methylcytosine restriction system component; InterPro IPR019292; KEGG: dau:Daud_0401 McrBC 5-methylcytosine restriction system component-like protein; PFAM: 5-methylcytosine restriction system component; SPTR: McrBC 5-methylcytosine restriction system component-like protein; PFAM: McrBC 5-methylcytosine restriction system component YP_004369939.1 InterPro IPR000551:IPR010093; KEGG: cjr:CJE0545 DNA binding domain-containing protein; PFAM: HTH transcriptional regulator, MerR; SPTR: DNA binding domain, excisionase; TIGRFAM: Excisionase/Xis, DNA-binding; PFAM: Prophage CP4-57 regulatory protein (AlpA); TIGRFAM: DNA binding domain, excisionase YP_004369940.1 KEGG: ckp:ckrop_1226 phage-related integrase; SPTR: Phage-related integrase YP_004369941.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: tye:THEYE_A0315 site specific recombinase; PFAM: Integrase, catalytic core, phage; SPTR: Site specific recombinase; PFAM: Phage integrase YP_004369942.1 KEGG: tgu:100231958 similar to rCG33450; SPTR: glutaminyl-tRNA synthetase YP_004369943.1 COGs: COG0461 Orotate phosphoribosyltransferase; KEGG: pho:PH1128 orotate phosphoribosyltransferase; SPTR: Orotate phosphoribosyltransferase YP_004369944.1 KEGG: mmq:MmarC5_1270 hypothetical protein; SPTR: uncharacterized protein YP_004369945.1 COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR001754; KEGG: mvn:Mevan_1474 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase domain; SMART: Orotidine 5'-phosphate decarboxylase domain; SPTR: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family YP_004369946.1 COGs: COG2378 transcriptional regulator protein; InterPro IPR013196; KEGG: gur:Gura_0944 helix-turn-helix, type 11 domain-containing protein; SPTR: Helix-turn-helix, type 11 domain protein; PFAM: HTH domain YP_004369947.1 KEGG: sat:SYN_02742 cytoplasmic protein; SPTR: uncharacterized protein YP_004369948.1 KEGG: pbe:PB001621.02.0 hypothetical protein; SPTR: uncharacterized protein YP_004369949.1 KEGG: scb:SCAB_33371 hypothetical protein; SPTR: uncharacterized protein YP_004369950.1 KEGG: ank:AnaeK_3944 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2791) YP_004369951.1 COGs: COG0433 ATPase; InterPro IPR002789; KEGG: ank:AnaeK_3943 hypothetical protein; PFAM: Domain of unknown function DUF87; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF87; Zonular occludens toxin (Zot) YP_004369952.1 KEGG: cpv:cgd2_3440 telomerase, reverse transcriptase; SPTR: Telomerase reverse transcriptase YP_004369953.1 InterPro IPR003356; KEGG: tag:Tagg_0886 N-6 DNA methylase; PFAM: DNA methylase, adenine-specific; SPTR: N-6 DNA methylase; PFAM: N-6 DNA methylase YP_004369954.1 KEGG: amr:AM1_2380 hypothetical protein; SPTR: ABC1 domain protein YP_004369955.1 KEGG: mcp:MCAP_0454 glycerol ABC transporter, ATP-binding protein; SPTR: uncharacterized protein YP_004369956.1 KEGG: emi:Emin_0857 hypothetical protein; SPTR: uncharacterized protein YP_004369957.1 InterPro IPR004919; KEGG: gbm:Gbem_2969 hypothetical protein; PFAM: Domain of unknown function DUF262; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF262 YP_004369958.1 KEGG: gbm:Gbem_2968 hypothetical protein; SPTR: uncharacterized protein YP_004369959.1 KEGG: gur:Gura_1849 hypothetical protein; SPTR: uncharacterized protein YP_004369960.1 COGs: COG2801 transposase and inactivated derivatives; InterPro IPR001584; KEGG: gur:Gura_1848 integrase catalytic subunit; PFAM: Integrase, catalytic core; SPTR: Integrase, catalytic region; PFAM: Integrase core domain YP_004369961.1 COGs: COG3177 conserved hypothetical protein; InterPro IPR003812; KEGG: syp:SYNPCC7002_F0100 Fic family protein; PFAM: Filamentation induced by cAMP/death on curing-related; SPTR: Fic family protein; PFAM: Fic/DOC family YP_004369962.1 COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356; KEGG: mtp:Mthe_1211 N-6 DNA methylase; PFAM: DNA methylase, adenine-specific; SPTR: N-6 DNA methylase; PFAM: N-6 DNA methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM) YP_004369963.1 KEGG: ote:Oter_3111 nucleotide-binding protein; SPTR: nucleotide-binding protein containing TIR-like protein domain-like protein YP_004369964.1 COGs: COG5421 transposase; KEGG: hha:Hhal_0784 transposase, IS4 family protein; SPTR: transposase, IS4 family protein; PFAM: transposase DDE domain YP_004369965.1 COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR005117:IPR006067; KEGG: sfu:Sfum_3159 nitrite and sulphite reductase 4Fe-4S region; PFAM: nitrite/sulphite reductase 4Fe-4S domain; nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; PRIAM: nitrite reductase (NAD(P)H); SPTR: nitrite and sulphite reductase 4Fe-4S region; PFAM: nitrite and sulphite reductase 4Fe-4S domain; nitrite/Sulfite reductase ferredoxin-like half domain YP_004369966.1 InterPro IPR011129:IPR002059:IPR003489; KEGG: dps:DP1086 cold-shock protein; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; SPTR: Similar to cold-shock protein; TIGRFAM: ribosomal protein S30Ae/sigma 54 modulation protein; PFAM: 'Cold-shock' DNA-binding domain; Sigma 54 modulation protein / S30EA ribosomal protein YP_004369967.1 COGs: COG1180 pyruvate-formate lyase-activating enzyme; InterPro IPR006638:IPR007197; KEGG: dak:DaAHT2_1232 radical SAM protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: radical SAM protein; PFAM: Radical SAM superfamily YP_004369968.1 KEGG: dbr:Deba_1538 zinc resistance-associated protein precursor; SPTR: uncharacterized protein YP_004369969.1 COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR001327:IPR001450; KEGG: mfv:Mfer_0184 cob--com heterodisulfide reductase subunit A; PFAM: 4Fe-4S binding domain; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; SPTR: Heterodisulfide reductase, subunit A, HdrA; PFAM: FAD dependent oxidoreductase YP_004369970.1 COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR003953:IPR001450:IPR003813; KEGG: dal:Dalk_1624 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase, delta subunit; 4Fe-4S binding domain; Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; SPTR: methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase, delta subunit; FAD binding domain; 4Fe-4S binding domain YP_004369971.1 InterPro IPR001450; KEGG: mka:MK0307 formylmethanofuran dehydrogenase subunit F, ferredoxin containing; PFAM: 4Fe-4S binding domain; SPTR: Probable formylmethanofuran dehydrogenase subunit F, ferredoxin containing YP_004369972.1 COGs: COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]; HAMAP: L-seryl-tRNA selenium transferase; InterPro IPR018319:IPR004534; KEGG: dak:DaAHT2_0215 L-seryl-tRNA selenium transferase; PFAM: Pyridoxal phosphate-dependent transferase; PRIAM: L-seryl-tRNA(Sec) selenium transferase; SPTR: L-seryl-tRNA(Sec) selenium transferase; TIGRFAM: L-seryl-tRNA selenium transferase; PFAM: Selenocysteine synthase N terminal; L-seryl-tRNA selenium transferase; TIGRFAM: seryl-tRNA(sec) selenium transferase YP_004369973.1 COGs: COG2068 Uncharacterized MobA-related protein; KEGG: dat:HRM2_07000 phosphoglycerate/bisphosphoglycerate mutase (phosphoglyceromutase) (PgaM); SPTR: phosphoglycerate/bisphosphoglycerate mutase (phosphoglyceromutase) (PGAM) YP_004369974.1 KEGG: pca:Pcar_1974 hypothetical protein; SPTR: uncharacterized protein YP_004369975.1 InterPro IPR002575; KEGG: sfu:Sfum_3260 aminoglycoside phosphotransferase; PFAM: Aminoglycoside phosphotransferase; SPTR: Aminoglycoside phosphotransferase; PFAM: phosphotransferase enzyme family YP_004369976.1 KEGG: deb:DehaBAV1_1339 methyltransferase type 11; SPTR: methyltransferase type 11 YP_004369977.1 COGs: COG2077 Peroxiredoxin; InterPro IPR013740; KEGG: sfu:Sfum_2340 redoxin domain-containing protein; PFAM: Redoxin; SPTR: Thiol peroxidase (Atypical 2-Cys peroxiredoxin); PFAM: Redoxin YP_004369978.1 COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR006268; KEGG: sfu:Sfum_1777 3-deoxy-7-phosphoheptulonate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase YP_004369979.1 COGs: COG0337 3-dehydroquinate synthetase; HAMAP: 3-dehydroquinate synthase AroB, subgroup; InterPro IPR002658:IPR016037; KEGG: dak:DaAHT2_0294 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase AroB; PRIAM: 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase AroB, subgroup; PFAM: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase YP_004369980.1 COGs: COG0038 Chloride channel protein EriC; InterPro IPR000644:IPR001807; KEGG: pca:Pcar_1620 chloride channel protein EriC; PFAM: Chloride channel, voltage gated; cystathionine beta-synthase, core; SMART: cystathionine beta-synthase, core; SPTR: Cl-channel voltage-gated family protein; PFAM: CBS domain; Voltage gated chloride channel YP_004369981.1 KEGG: gur:Gura_2702 hypothetical protein; SPTR: uncharacterized protein YP_004369982.1 KEGG: cho:Chro.20049 hypothetical protein; SPTR: Expressed protein DH12 YP_004369983.1 COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR001962; KEGG: gur:Gura_1346 asparagine synthase; PFAM: Asparagine synthase; PRIAM: Asparagine synthase (glutamine-hydrolyzing); SPTR: Asparagine synthase; PFAM: Asparagine synthase YP_004369984.1 KEGG: gsu:GSU2476 TPR domain protein; SPTR: TPR domain protein; PFAM: ribosomal protein L11 methyltransferase (PrmA) YP_004369985.1 KEGG: gur:Gura_1356 hypothetical protein; SPTR: uncharacterized protein YP_004369986.1 KEGG: amr:AM1_1921 hypothetical protein; SPTR: uncharacterized protein; PFAM: Coenzyme PQQ synthesis protein D (PqqD) YP_004369987.1 InterPro IPR000863; KEGG: ppd:Ppro_0057 sulfotransferase; PFAM: Sulfotransferase domain; SPTR: Sulfotransferase; PFAM: Sulfotransferase domain YP_004369988.1 KEGG: dae:Dtox_3276 HPr kinase; SPTR: HPr kinase; PFAM: HPr Serine kinase C-terminal domain YP_004369989.1 COGs: COG1171 Threonine dehydratase; InterPro IPR001926:IPR002912:IPR005789; KEGG: sfu:Sfum_0736 threonine dehydratase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Amino acid-binding ACT; SPTR: L-threonine ammonia-lyase; TIGRFAM: Threonine dehydratase II; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine dehydratase, medium form YP_004369990.1 KEGG: rsq:Rsph17025_3021 hypothetical protein; SPTR: uncharacterized protein YP_004369991.1 KEGG: gem:GM21_0952 histidine kinase; SPTR: Type I restriction enzyme, R protein YP_004369992.1 COGs: COG1758 DNA-directed RNA polymerase subunit K/omega; HAMAP: DNA-directed RNA polymerase, omega subunit; InterPro IPR006110:IPR003716; KEGG: dbr:Deba_0459 DNA-directed RNA polymerase, omega subunit; PFAM: RNA polymerase, subunit omega/K/RPABC2; SPTR: DNA-directed RNA polymerase, omega subunit; TIGRFAM: DNA-directed RNA polymerase, omega subunit; PFAM: RNA polymerase Rpb6; TIGRFAM: DNA-directed RNA polymerase, omega subunit YP_004369993.1 KEGG: avn:Avin_33120 cobyrinic acid a,c-diamide synthase; SPTR: uncharacterized protein YP_004369994.1 COGs: COG5496 thioesterase; KEGG: sfu:Sfum_2467 hypothetical protein; SPTR: Thioesterase superfamily; PFAM: Thioesterase superfamily YP_004369995.1 COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: dal:Dalk_3455 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase YP_004369996.1 COGs: COG1043 acyl-(acyl carrier protein); InterPro IPR001451:IPR010137; KEGG: gme:Gmet_2567 UDP-N-acetylglucosamine acyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM:acyl-[acyl-carrier-protein]--UDP-N-acetylgluc osamineO-acyltransferase; SPTR:acyl-[acyl-carrier-protein]--UDP-N-acetylgluco samineO-acyltransferase; TIGRFAM:acyl-[acyl-carrier-protein]--UDP-N-acetylgl ucosamineO-acyltransferase; TIGRFAM: acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase YP_004369997.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: sfu:Sfum_0374 glycosyl transferase; PFAM: glycosyl transferase, family 2; SPTR: glycosyl transferase, family 2; PFAM: glycosyl transferase 2 YP_004369998.1 InterPro IPR005651; KEGG: sfu:Sfum_3635 hypothetical protein; PFAM: Uncharacterised protein family UPF0434/Trm112; SPTR: uncharacterized protein; PFAM: Trm112p-like protein YP_004369999.1 COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201:IPR011908:IPR011910; KEGG: dbr:Deba_2090 lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase, family 9; SPTR: Lipopolysaccharide heptosyltransferase I; TIGRFAM: Lipopolysaccharide heptosyltransferase I; Lipopolysaccharide heptosyltransferase II; PFAM: glycosyltransferase 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase I; lipopolysaccharide heptosyltransferase II YP_004370000.1 COGs: COG0241 histidinol phosphatase and related phosphatase; InterPro IPR005834:IPR006543:IPR006549; KEGG: aar:Acear_0221 hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Hydrolase, HAD-superfamily, subfamily IIIA; TIGRFAM: histidinol-phosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosphatase domain; histidinol-phosphatase YP_004370001.1 COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201:IPR011910; KEGG: gsu:GSU2256 ADP-heptose--LPS heptosyltransferase II; PFAM: glycosyl transferase, family 9; SPTR: ADP-heptose--LPS heptosyltransferase II, ; TIGRFAM: Lipopolysaccharide heptosyltransferase II; PFAM: glycosyltransferase 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase II YP_004370002.1 COGs: COG1663 Tetraacyldisaccharide-1-P 4'-kinase; HAMAP: tetraacyldisaccharide 4'-kinase; InterPro IPR003758; KEGG: glo:Glov_0771 tetraacyldisaccharide 4'-kinase; PFAM: tetraacyldisaccharide 4'-kinase; PRIAM: tetraacyldisaccharide 4'-kinase; SPTR: tetraacyldisaccharide 4'-kinase; TIGRFAM: tetraacyldisaccharide 4'-kinase; PFAM: Tetraacyldisaccharide-1-P 4'-kinase; TIGRFAM: tetraacyldisaccharide 4'-kinase YP_004370003.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439:IPR011917; KEGG: dbr:Deba_2101 lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; PFAM: ABC transporter-like; ABC transporter, transmembrane domain; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; TIGRFAM: ABC transporter, lipid A export, MsbA; PFAM: ABC transporter; ABC transporter transmembrane region; TIGRFAM: lipid A export permease/ATP-binding protein MsbA YP_004370004.1 COGs: COG2191 formylmethanofuran dehydrogenase subunit E; InterPro IPR003814; KEGG: aar:Acear_0784 formylmethanofuran dehydrogenase subunit E region; PFAM: formylmethanofuran dehydrogenase, subunit E domain; SPTR: formylmethanofuran dehydrogenase subunit E region; PFAM: Prokaryotic dksA/traR C4-type zinc finger; FmdE, Molybdenum formylmethanofuran dehydrogenase operon YP_004370005.1 COGs: COG0805 Sec-independent protein secretion pathway component TatC; InterPro IPR002033:IPR019822; KEGG: gem:GM21_1626 sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; SPTR: Sec-independent protein translocase, TatC subunit; TIGRFAM: Twin arginine-targeting protein translocase, TatC; manually curated; PFAM: Sec-independent protein translocase (TatC); TIGRFAM: Twin arginine targeting (Tat) protein translocase TatC YP_004370007.1 KEGG: pth:PTH_2492 hypothetical protein; SPTR: uncharacterized protein YP_004370008.1 COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR002589; KEGG: sat:SYN_01003 appr-1-p histone processing protein; PFAM: Appr-1-p processing; SMART: Appr-1-p processing; SPTR: Appr-1-p histone processing protein; PFAM: Macro domain YP_004370009.1 COGs: COG3640 CO dehydrogenase maturation factor; KEGG: dal:Dalk_1102 cobyrinic acid ac-diamide synthase; SPTR: cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004370010.1 COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086; KEGG: rxy:Rxyl_0013 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase; PFAM: NUDIX domain YP_004370011.1 InterPro IPR008915; KEGG: tye:THEYE_A0856 metalloprotease; PFAM: peptidase M50; SPTR: Metalloprotease; PFAM: peptidase M50 YP_004370012.1 COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942:IPR006145:IPR000748; KEGG: adg:Adeg_1292 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RsuA/RluB/E/F; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase YP_004370013.1 COGs: COG0180 Tryptophanyl-tRNA synthetase; InterPro IPR002305:IPR002306; KEGG: sat:SYN_02857 tryptophanyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ib; PRIAM: Tryptophan--tRNA ligase; SPTR: Tryptophanyl-tRNA synthetase; TIGRFAM: Tryptophanyl-tRNA synthetase, class Ib; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tryptophanyl-tRNA synthetase YP_004370014.1 InterPro IPR010181; KEGG: sfu:Sfum_2625 hypothetical protein; PFAM: CGCAxxGCC motif; SPTR: hypothetical protein; TIGRFAM: CGCAxxGCC motif; PFAM: redox-active protein (C_GCAxxG_C_C); TIGRFAM: C_GCAxxG_C_C family probable redox protein YP_004370015.1 COGs: COG1278 Cold shock protein; InterPro IPR011129:IPR002059; KEGG: tjr:TherJR_2777 cold-shock DNA-binding domain protein; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; SPTR: Cold-shock DNA-binding domain protein; PFAM: 'Cold-shock' DNA-binding domain YP_004370016.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sat:SYN_01340 endonuclease IV; PFAM: Xylose isomerase, TIM barrel domain; SPTR: AP endonuclease, family 2; PFAM: Xylose isomerase-like TIM barrel YP_004370017.1 InterPro IPR004360:IPR017515; KEGG: toc:Toce_1197 methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: methylmalonyl-CoA epimerase; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase YP_004370018.1 COGs: COG1197 transcription-repair coupling factor (superfamily II helicase); InterProIPR014001:IPR001650:IPR003711:IPR011545:IPR 005118:IPR004576; KEGG: dal:Dalk_0050 transcription-repair coupling factor; PFAM: transcription factor CarD; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; transcription-repair-coupling factor domain; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: Helicase conserved C-terminal domain; TRCF domain; CarD-like/TRCF domain; DEAD/DEAH box helicase; TIGRFAM: transcription-repair coupling factor (mfd) YP_004370019.1 InterPro IPR015391:IPR000297; KEGG: dol:Dole_1707 peptidyl-prolyl cis-trans isomerase; PFAM: SurA N-terminal; peptidyl-prolyl cis-trans isomerase, PpiC-type; SPTR: peptidyl-prolyl cis-trans isomerase; PFAM: SurA N-terminal domain; PPIC-type PPIASE domain YP_004370020.1 COGs: COG0017 aspartyl/asparaginyl-tRNA synthetase; HAMAP: Asparaginyl-tRNA synthetase, class IIb; InterPro IPR004365:IPR004364:IPR004522; KEGG: drm:Dred_1281 asparaginyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: Asparagine--tRNA ligase; SPTR: Asparaginyl-tRNA synthetase; TIGRFAM: Asparaginyl-tRNA synthetase, class IIb; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase YP_004370021.1 COGs: COG4889 helicase; KEGG: sti:Sthe_0276 DNA methyltransferase; SPTR: DNA methyltransferase YP_004370022.1 KEGG: bpm:BURPS1710b_3602 hypothetical protein; SPTR: peptide chain release factor 2; manually curated; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 2 YP_004370023.1 InterPro IPR007167; KEGG: dsa:Desal_0100 FeoA family protein; PFAM: Ferrous iron transporter, FeoA subunit; SPTR: FeoA family protein; PFAM: FeoA domain YP_004370024.1 COGs: COG2217 Cation transport ATPase; InterPro IPR008250:IPR005834:IPR006416:IPR001757; KEGG: dde:Dde_0495 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Haloacid dehalogenase-like hydrolase; PRIAM: Cadmium-exporting ATPase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004370025.1 KEGG: rru:Rru_A1028 hypothetical protein; SPTR: uncharacterized protein YP_004370027.1 KEGG: dap:Dacet_2133 hypothetical protein; SPTR: uncharacterized protein YP_004370028.1 KEGG: dap:Dacet_2134 hypothetical protein; SPTR: uncharacterized protein YP_004370029.1 KEGG: nvi:100116536 similar to conserved hypothetical protein; SPTR: Flagelliform silk protein-1 YP_004370030.1 KEGG: rpt:Rpal_2581 hypothetical protein; SPTR: uncharacterized protein YP_004370031.1 COGs: COG2217 Cation transport ATPase; InterPro IPR008250:IPR005834:IPR006416:IPR001757; KEGG: dbr:Deba_0546 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Haloacid dehalogenase-like hydrolase; PRIAM: Zinc-exporting ATPase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004370032.1 COGs: COG0370 Fe2+ transport system protein B; InterProIPR002917:IPR011619:IPR011642:IPR011640:IPR 005225:IPR003373; KEGG: dvm:DvMF_1015 ferrous iron transport protein B; PFAM: GTP-binding protein, HSR1-related; Ferrous iron transport protein B, N-terminal; nucleoside recognition; Ferrous iron transport protein B, C-terminal; SPTR: Ferrous iron transport protein B; TIGRFAM: Ferrous iron transport protein B; Small GTP-binding protein; PFAM: Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB; small GTP-binding protein domain YP_004370033.1 InterPro IPR007167; KEGG: dba:Dbac_1621 FeoA family protein; PFAM: Ferrous iron transporter, FeoA subunit; SMART: Ferrous iron transporter, FeoA subunit; SPTR: FeoA family protein; PFAM: FeoA domain YP_004370034.1 COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR022689:IPR007167:IPR022687:IPR001367; KEGG: sfu:Sfum_3768 DtxR family iron dependent repressor; PFAM: Iron dependent repressor, N-terminal; Iron dependent repressor; Ferrous iron transporter, FeoA subunit; SMART: Iron dependent repressor, diptheria toxin type; Ferrous iron transporter, FeoA subunit; SPTR: uncharacterized protein; PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain YP_004370035.1 COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: sfu:Sfum_2811 RND family efflux transporter MFP subunit; PFAM: Secretion protein HlyD; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004370036.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439:IPR003838; KEGG: sfu:Sfum_2810 ABC transporter related; PFAM: ABC transporter-like; Domain of unknown function DUF214, ABC transporter permease; PRIAM: phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Macrolide export ATP-binding/permease MacB; PFAM: ABC transporter; Predicted permease; TIGRFAM: phosphonate C-P lyase system protein PhnL YP_004370037.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423:IPR010131; KEGG: sfu:Sfum_2809 RND efflux system outer membrane lipoprotein; PFAM: Outer membrane efflux protein; SPTR: RND efflux system, outer membrane lipoprotein, NodT family; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT; PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family YP_004370038.1 COGs: COG0509 glycine cleavage system H protein (lipoate-binding); InterPro IPR002930; KEGG: sfu:Sfum_2805 glycine cleavage H-protein; PFAM: glycine cleavage H-protein; SPTR: glycine cleavage H-protein; PFAM: glycine cleavage H-protein YP_004370039.1 COGs: COG1913 Zn-dependent protease; InterPro IPR012962; KEGG: sfu:Sfum_2804 peptidase, zinc-dependent; PFAM: peptidase M54, archaemetzincin; SPTR: peptidase, zinc-dependent; PFAM: peptidase M54 YP_004370040.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: afw:Anae109_1798 two component, sigma54 specific, fis family transcriptional regulator; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: Acetoacetate metabolism regulatory protein atoC; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004370041.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR000014:IPR003661:IPR003594:IPR013656; KEGG: sfu:Sfum_0826 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; SPTR: uncharacterized protein; TIGRFAM: PAS; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004370042.1 COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR019591; KEGG: sfu:Sfum_1303 hypothetical protein; PFAM: ATPase-like, ParA/MinD; SPTR: uncharacterized protein; PFAM: ParA/MinD ATPase like; Anion-transporting ATPase YP_004370043.1 COGs: COG0456 Acetyltransferase; InterPro IPR000182; KEGG: rba:RB5015 ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Probable ribosomal-protein-alanine acetyltransferase; PFAM: Acetyltransferase (GNAT) family YP_004370044.1 KEGG: tte:TTE0710 hypothetical protein; SPTR: FAD dependent oxidoreductase YP_004370045.1 COGs: COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); HAMAP: glutamyl-tRNA(Gln) amidotransferase, B subunit; InterPro IPR018027:IPR006075:IPR004413; KEGG: sfu:Sfum_1705 aspartyl/glutamyl-tRNA amidotransferase subunit B; PFAM: glutamyl-tRNA(Gln) amidotransferase, subunit B/E, N-terminal; Asn/Gln amidotransferase; SMART: Asn/Gln amidotransferase; SPTR: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 1; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, B subunit; PFAM: GatB/GatE catalytic domain; GatB domain; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit YP_004370046.1 COGs: COG1635 Flavoprotein involved in thiazole biosynthesis; HAMAP: Thiazole biosynthetic enzyme, InterPro IPR002922:IPR022828; KEGG: mmg:MTBMA_c02060 thiazole biosynthesis protein; SPTR: ribose 1,5-bisphosphate isomerase; TIGRFAM: Thiamine biosynthesis Thi4 protein; PFAM: Thi4 family; TIGRFAM: thiazole biosynthesis enzyme YP_004370047.1 COGs: COG0782 transcription elongation factor; InterPro IPR022691:IPR001437; KEGG: scl:sce3595 transcription elongation factor GreA; PFAM: transcription elongation factor, GreA/GreB, N-terminal; transcription elongation factor, GreA/GreB, C-terminal; SPTR: transcription elongation factor GreA; PFAM: domain; transcription elongation factor, GreA/GreB, C-term YP_004370048.1 COGs: COG1067 ATP-dependent protease; InterPro IPR008269; KEGG: sfu:Sfum_0020 ATP-dependent protease, PFAM: peptidase S16, Lon C-terminal; SPTR: ATP-dependent protease, ; PFAM: Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: lon-related ATP-dependent protease YP_004370049.1 InterPro IPR019410; KEGG: sfu:Sfum_0452 methyltransferase type 12; PFAM: methyltransferase-16, SPTR: methyltransferase type 12; PFAM: methyltransferase YP_004370050.1 COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: dat:HRM2_11700 HyaD2; PFAM: peptidase A31, hydrogen uptake protein; SPTR: HyaD2; TIGRFAM: peptidase A31, hydrogen uptake protein; PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease YP_004370051.1 COGs: COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); InterPro IPR000688; KEGG: mpd:MCP_2593 probable hydrogenase nickel incorporation protein HypA; PFAM: Hydrogenase nickel incorporation protein HypA/HybF; SPTR: Probable hydrogenase nickel incorporation protein hypA; PFAM: Hydrogenase expression/synthesis hypA family; TIGRFAM: hydrogenase nickel insertion protein HypA YP_004370052.1 COGs: COG4802 Ferredoxin-thioredoxin reductase catalytic subunit; KEGG: dol:Dole_2967 hypothetical protein; SPTR: uncharacterized protein; PFAM: Ferredoxin thioredoxin reductase catalytic beta chain YP_004370053.1 InterPro IPR002109; KEGG: drt:Dret_1406 glutaredoxin; PFAM: glutaredoxin; SPTR: glutaredoxin; PFAM: glutaredoxin YP_004370054.1 COGs: COG0583 transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: alv:Alvin_2795 LysR family transcriptional regulator; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: LysR family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain YP_004370055.1 COGs: COG5496 thioesterase; KEGG: mac:MA0038 hypothetical protein; SPTR: Predicted protein YP_004370056.1 COGs: COG4871 conserved hypothetical protein; InterPro IPR007202; KEGG: sfu:Sfum_3600 Fe-S cluster domain-containing protein; PFAM: Fe-S cluster; SPTR: Fe-S cluster domain protein; PFAM: Fe-S cluster YP_004370057.1 COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: gbm:Gbem_3625 phosphoribosylaminoimidazole carboxylase-like protein; PFAM: phosphoribosylaminoimidazole carboxylase, core; SPTR: phosphoribosylaminoimidazole carboxylase-related protein; PFAM: AIR carboxylase YP_004370058.1 COGs: COG1215 glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173:IPR017835; KEGG: gme:Gmet_2815 ceramide glucosyltransferase; PFAM: glycosyl transferase, family 2; SPTR: Ceramide glucosyltransferase, ; TIGRFAM: glycosyl transferase, family 2, hopene-associated, HpnI; PFAM: glycosyl transferase 2; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase HpnI YP_004370059.1 COGs: COG2945 hydrolase of the alpha/beta superfamily; KEGG: dol:Dole_3190 alpha/beta hydrolase; SPTR: uncharacterized protein YP_004370060.1 KEGG: sfu:Sfum_3755 transposase, IS4 family protein; SPTR: transposase, IS4 family YP_004370061.1 KEGG: pmc:P9515_04871 hypothetical protein; SPTR: 3-deoxy-D-manno-octulosonic-acid transferase YP_004370062.1 KEGG: ago:AGOS_AAL099C hypothetical protein; SPTR: Cell surface protein YP_004370064.1 KEGG: bfu:BC1G_03858 hypothetical protein; SPTR: uncharacterized protein YP_004370065.1 KEGG: pdi:BDI_0644 Na+/sulphate transporter; SPTR: Na+/sulphate transporter YP_004370066.1 KEGG: bja:bll1568 hypothetical protein; SPTR: uncharacterized protein YP_004370067.1 KEGG: ajs:Ajs_0477 hypothetical protein; SPTR: uncharacterized protein; PFAM: transmembrane exosortase (Exosortase_EpsH) YP_004370068.1 KEGG: ipo:Ilyop_1264 hypothetical protein; SPTR: acyltransferase 3 YP_004370069.1 COGs: COG1215 glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: gme:Gmet_2815 ceramide glucosyltransferase; PFAM: glycosyl transferase, family 2; SPTR: Hopanoid biosynthesis associated glycosyl transferase HpnI; PFAM: glycosyl transferase 2; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase HpnI YP_004370070.1 COGs: COG2945 hydrolase of the alpha/beta superfamily; KEGG: dol:Dole_3190 alpha/beta hydrolase; SPTR: uncharacterized protein YP_004370071.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: gsu:GSU0773 multidrug resistance protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Multidrug resistance protein, ; PFAM: Major Facilitator Superfamily YP_004370072.1 COGs: COG2937 glycerol-3-phosphate O-acyltransferase; InterPro IPR002123; KEGG: sfu:Sfum_3097 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; PRIAM: glycerol-3-phosphate O-acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: glycerol-3-phosphate acyltransferase; PFAM: acyltransferase; TIGRFAM: glycerol-3-phosphate O-acyltransferase YP_004370073.1 KEGG: lbz:LbrM18_V2.1010 hypothetical protein; SPTR: HhH-GPD family protein YP_004370074.1 COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221:IPR004101:IPR001645; KEGG: sfu:Sfum_1671 FolC bifunctional protein; PFAM: Mur ligase, C-terminal; Mur ligase, central; PRIAM: Tetrahydrofolate synthase; SPTR: FolC bifunctional protein; TIGRFAM: Folylpolyglutamate synthetase; PFAM: Mur ligase, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase YP_004370075.1 COGs: COG0752 glycyl-tRNA synthetase alpha subunit; HAMAP: glycyl-tRNA synthetase, class IIc, alpha subunit; InterPro IPR002310; KEGG: pca:Pcar_0598 glycyl-tRNA synthetase subunit alpha; PFAM: glycyl-tRNA synthetase, class IIc, alpha subunit; PRIAM: glycine--tRNA ligase; SPTR: glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, class IIc, alpha subunit; PFAM: glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, alpha subunit YP_004370076.1 COGs: COG0751 glycyl-tRNA synthetase beta subunit; HAMAP: glycyl-tRNA synthetase, class IIc, beta subunit; InterPro IPR002311:IPR008909:IPR015944; KEGG: sat:SYN_01537 glycyl-tRNA synthetase subunit beta; PFAM: glycyl-tRNA synthetase, class IIc, beta subunit, N-terminal; DALR anticodon binding; PRIAM: glycine--tRNA ligase; SPTR: glycyl-tRNA synthetase beta subunit; TIGRFAM: glycyl-tRNA synthetase, class IIc, beta subunit; PFAM: glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, beta subunit YP_004370077.1 COGs: COG0552 Signal recognition particle GTPase; InterPro IPR013822:IPR003593:IPR000897:IPR004390; KEGG: dbr:Deba_1973 signal recognition particle-docking protein FtsY; PFAM: Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, helical bundle; SMART: Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, helical bundle; ATPase, AAA+ type, core; SPTR: Signal recognition particle-docking protein FtsY; TIGRFAM: Cell division transporter substrate-binding protein FtsY; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; TIGRFAM: signal recognition particle-docking protein FtsY YP_004370078.1 InterPro IPR006976; KEGG: bcl:ABC0533 phosphotransbutyrylase; PFAM: VanZ-like; SPTR: VanZ family protein; PFAM: VanZ like family YP_004370079.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765:IPR007863:IPR019576; KEGG: nde:NIDE3729 M16 family Zn-dependent peptidase; PFAM: peptidase M16, C-terminal; peptidase M16, N-terminal; Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal; PRIAM: processing peptidase; SPTR: Zn-dependent protease, involved in pqq synthesis (PpqF); PFAM: peptidase M16 inactive domain; Insulinase (peptidase M16) YP_004370080.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765:IPR007863; KEGG: nde:NIDE3730 M16 family Zn-dependent peptidase; PFAM: peptidase M16, C-terminal; peptidase M16, N-terminal; PRIAM: processing peptidase; SPTR: peptidase M16 domain protein, involved in ppq synthesis (PpqG); PFAM: peptidase M16 inactive domain; Insulinase (peptidase M16) YP_004370081.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478:IPR001254:IPR011782; KEGG: gme:Gmet_1014 peptidase S1C, Do; PFAM: peptidase S1/S6, chymotrypsin/Hap; PDZ/DHR/GLGF; PRIAM: HtrA2 peptidase; SMART: PDZ/DHR/GLGF; SPTR: peptidase S1C, Do; TIGRFAM: peptidase S1C, Do; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease, Do/DeqQ family YP_004370082.1 COGs: COG0070 glutamate synthase domain 3; InterPro IPR002489; KEGG: geo:Geob_3276 glutamine amidotransferase class-II; PFAM: glutamate synthase, alpha subunit, C-terminal; SPTR: uncharacterized protein; PFAM: GXGXG motif; glutamine amidotransferases class-II YP_004370083.1 COGs: COG0069 glutamate synthase domain 2; InterPro IPR001450:IPR002932; KEGG: pfu:PF0205 glutamate synthase subunit alpha; PFAM: glutamate synthase, central-C; 4Fe-4S binding domain; PRIAM: glutamate synthase (NADPH); SPTR: uncharacterized protein; PFAM: Conserved region in glutamate synthase YP_004370084.1 COGs: COG0069 glutamate synthase domain 2; InterPro IPR002932; KEGG: pfu:PF0205 glutamate synthase subunit alpha; PFAM: glutamate synthase, central-C; SPTR: 4Fe-4S binding domain protein; PFAM: Conserved region in glutamate synthase YP_004370085.1 KEGG: dbr:Deba_2152 hypothetical protein; SPTR: uncharacterized protein; PFAM: methylene-tetrahydrofolate reductase C terminal YP_004370086.1 COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: dbr:Deba_2151 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase, delta subunit; SPTR: methyl-viologen-reducing hydrogenase, delta subunit; PFAM: methyl-viologen-reducing hydrogenase, delta subunit YP_004370087.1 COGs: COG0174 glutamine synthetase; InterPro IPR008147:IPR008146:IPR004809; KEGG: sat:SYN_01628 glutamine synthetase; PFAM: glutamine synthetase, catalytic domain; glutamine synthetase, beta-Grasp; PRIAM: glutamate--ammonia ligase; SPTR: glutamine synthetase; TIGRFAM: glutamine synthetase type I; PFAM: glutamine synthetase, catalytic domain; glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I YP_004370088.1 COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR002474:IPR000991:IPR006274; KEGG: pca:Pcar_1613 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit YP_004370089.1 KEGG: mar:MAE_00130 hypothetical protein; SPTR: uncharacterized protein YP_004370090.1 InterPro IPR005357; KEGG: mar:MAE_00140 hypothetical protein; PFAM: Uncharacterised protein family UPF0150; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0150) YP_004370091.1 InterPro IPR005357; KEGG: mem:Memar_1245 hypothetical protein; PFAM: Uncharacterised protein family UPF0150; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0150) YP_004370092.1 COGs: COG0012 GTPase probable translation factor; InterPro IPR013029; KEGG: pth:PTH_0927 GTP-dependent nucleic acid-binding protein EngD; PFAM: Domain of unknown function DUF933; SPTR: Predicted GTPase, probable translation factor; PFAM: protein of unknown function (DUF933) YP_004370093.1 InterPro IPR002934; KEGG: gur:Gura_2470 DNA polymerase beta subunit; PFAM: nucleotidyl transferase domain; SPTR: DNA polymerase, beta domain protein region; PFAM: nucleotidyltransferase domain YP_004370094.1 InterPro IPR007842; KEGG: gur:Gura_2469 HEPN domain-containing protein; PFAM: HEPN; SMART: HEPN; SPTR: HEPN domain protein; manually curated; PFAM: HEPN domain YP_004370095.1 COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR011607:IPR005481:IPR005479:IPR005480:IPR 006275; KEGG: dbr:Deba_3126 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: methylglyoxal synthase-like domain; SPTR: Carbamoyl-phosphate synthase, large subunit; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit YP_004370096.1 COGs: COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing); HAMAP: Carbon storage regulator; InterPro IPR003751; KEGG: cbg:CbuG_0954 carbon storage regulator; PFAM: Carbon storage regulator; SPTR: Carbon storage regulator; TIGRFAM: Carbon storage regulator; PFAM: Global regulator protein family; TIGRFAM: carbon storage regulator (csrA) YP_004370097.1 KEGG: bfu:BC1G_07672 hypothetical protein; SPTR: uncharacterized protein YP_004370098.1 COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: aba:Acid345_3865 glucokinase; PFAM: ROK; PRIAM: glucokinase; SPTR: glucokinase; PFAM: ROK family; TIGRFAM: ROK family protein ( glucokinase) YP_004370099.1 COGs: COG0009 translation factor (SUA5); InterPro IPR006070:IPR004388; KEGG: dak:DaAHT2_1346 SUA5/YciO/YrdC/YwlC family protein; PFAM: Sua5/YciO/YrdC, N-terminal; SPTR: Sua5/YciO/YrdC/YwlC; TIGRFAM: Sua5/YciO/YrdC/YwlC; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein YP_004370100.1 COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR019575:IPR002023:IPR011538:IPR019554; KEGG: sat:SYN_02139 NADH-quinone oxidoreductase chain F; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; NADH:ubiquinone oxidoreductase, 24kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: NADH-quinone oxidoreductase chain F; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain YP_004370101.1 COGs: COG3383 Uncharacterized anaerobic dehydrogenase; Contains selenocysteine; InterProIPR019574:IPR006963:IPR001041:IPR001450:IPR 006656:IPR006657:IPR006478; KEGG: sfu:Sfum_3509 formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S binding domain; Molydopterin dinucleotide-binding domain; PRIAM: nitrate reductase; SMART: Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; SPTR: formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; manually curated; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; 4Fe-4S binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: formate dehydrogenase, alpha subunit, archaeal-type YP_004370102.1 COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR001453:IPR003814; KEGG: sfu:Sfum_0032 molybdopterin binding domain-containing protein; PFAM: formylmethanofuran dehydrogenase, subunit E domain; Molybdopterin binding; SMART: Molybdopterin binding; SPTR: Molybdopterin binding domain; PFAM: Probable molybdopterin binding domain; FmdE, Molybdenum formylmethanofuran dehydrogenase operon; TIGRFAM: molybdenum cofactor synthesis domain YP_004370103.1 COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: mac:MA3903 sugar ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Sugar ABC transporter, ATP-binding protein; PFAM: ABC transporter YP_004370104.1 COGs: COG4149 ABC-type molybdate transport system permease component; InterPro IPR000515:IPR011867; KEGG: mbu:Mbur_1552 molybdate ABC transporter inner membrane protein; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Molybdenum ABC transporter, permease; TIGRFAM: Molybdate ABC transporter, permease; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: molybdate ABC transporter, permease YP_004370105.1 COGs: COG0725 ABC-type molybdate transport system periplasmic component; InterPro IPR006059:IPR005950; KEGG: cyc:PCC7424_4992 molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Molybdenum ABC transporter, periplasmic molybdate-binding protein; TIGRFAM: Molybdenum ABC transporter, periplasmic binding protein; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein YP_004370106.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR011545; KEGG: gur:Gura_1632 DEAD/DEAH box helicase domain-containing protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: DEAD/DEAH box helicase; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_004370107.1 KEGG: dan:Dana_GF14453 GF14453 gene product from transcript GF14453-RA; SPTR: GF14453 YP_004370108.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR006158:IPR007197; KEGG: nde:NIDE0843 hypothetical protein; PFAM: Radical SAM; Cobalamin (vitamin B12)-binding; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; PFAM: Radical SAM superfamily; B12 binding domain YP_004370109.1 COGs: COG0724 RNA-binding protein (RRM domain); InterPro IPR000504; KEGG: sfu:Sfum_0084 RNP-1 like RNA-binding protein; PFAM: RNA recognition motif domain; SMART: RNA recognition motif domain; SPTR: RNP-1 like RNA-binding protein; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YP_004370110.1 COGs: COG1278 Cold shock protein; InterPro IPR011129:IPR002059; KEGG: sus:Acid_7238 cold-shock DNA-binding protein family protein; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; SPTR: Cold-shock DNA-binding protein family; PFAM: 'Cold-shock' DNA-binding domain YP_004370111.1 COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR019575:IPR002023:IPR011538:IPR019554; KEGG: sat:SYN_02139 NADH-quinone oxidoreductase chain F; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; NADH:ubiquinone oxidoreductase, 24kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: NADH-quinone oxidoreductase chain F; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain YP_004370112.1 COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR019574:IPR006963:IPR001041:IPR001450:IPR 006656:IPR006657:IPR006478; KEGG: sfu:Sfum_3509 formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S binding domain; Molydopterin dinucleotide-binding domain; PRIAM: nitrate reductase; SMART: Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; SPTR: formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin oxidoreductase; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: formate dehydrogenase, alpha subunit, archaeal-type YP_004370113.1 InterPro IPR007159; KEGG: cyc:PCC7424_1193 transcriptional regulator/antitoxin, MazE; SMART: transcription regulator AbrB/SpoV, predicted; SPTR: transcriptional regulator/antitoxin, MazE; PFAM: SpoVT / AbrB like domain YP_004370114.1 COGs: COG2337 Growth inhibitor; InterPro IPR003477; KEGG: cyn:Cyan7425_3432 transcriptional modulator of MazE/toxin, MazF; PFAM: PemK-like protein; SPTR: transcriptional modulator of MazE/toxin, MazF; PFAM: PemK-like protein YP_004370115.1 COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR019575:IPR002023:IPR011538:IPR019554; KEGG: sat:SYN_02139 NADH-quinone oxidoreductase chain F; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; NADH:ubiquinone oxidoreductase, 24kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: NADH-quinone oxidoreductase chain F; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain YP_004370116.1 COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR019574:IPR006963:IPR001041:IPR001450:IPR 006656:IPR006657:IPR006478; KEGG: dat:HRM2_16890 FdhA6; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S binding domain; Molydopterin dinucleotide-binding domain; PRIAM: nitrate reductase; SMART: Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; SPTR: FdhA6; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin oxidoreductase; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: formate dehydrogenase, alpha subunit, archaeal-type YP_004370117.1 COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR019575:IPR002023:IPR011538:IPR019554; KEGG: sat:SYN_02139 NADH-quinone oxidoreductase chain F; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; NADH:ubiquinone oxidoreductase, 24kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: NADH-quinone oxidoreductase chain F; manually curated; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain YP_004370118.1 COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR006656:IPR006657; KEGG: dat:HRM2_16890 FdhA6; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding domain; PRIAM: nitrate reductase; SPTR: FdhA6; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; TIGRFAM: formate dehydrogenase, alpha subunit, archaeal-type YP_004370119.1 COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR019574:IPR006963:IPR001041:IPR001450:IPR 006656; KEGG: dbr:Deba_2120 NADH dehydrogenase (quinone); PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S binding domain; PRIAM: NADH dehydrogenase (quinone); SMART: Molybdopterin oxidoreductase, Fe4S4 domain; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; SPTR: NADH dehydrogenase (Quinone); PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin oxidoreductase; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; 4Fe-4S binding domain; Molybdopterin oxidoreductase Fe4S4 domain YP_004370120.1 KEGG: rfr:Rfer_1522 succinylglutamate desuccinylase/aspartoacylase; SPTR: Succinylglutamate desuccinylase/aspartoacylase YP_004370121.1 COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR003593:IPR003439; KEGG: drt:Dret_1000 ABC transporter related; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC YP_004370122.1 COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR000825; KEGG: sfu:Sfum_0163 SufBD protein; PFAM: SUF system FeS cluster assembly, SufBD; SPTR: SufBD protein; PFAM: Uncharacterized protein family (UPF0051) YP_004370123.1 InterPro IPR000551; KEGG: dbr:Deba_0666 transcriptional regulator, MerR family; PFAM: HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: transcriptional regulator, MerR family; PFAM: MerR family regulatory protein YP_004370124.1 COGs: COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein; InterPro IPR004435; KEGG: tbd:Tbd_1024 molybdopterin-guanine dinucleotide biosynthesis MobB; SPTR: uncharacterized protein; TIGRFAM: Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB), conserved domain; PFAM: Molybdopterin guanine dinucleotide synthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein MobB YP_004370125.1 COGs: COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A; HAMAP: Molybdopterin-guanine dinucleotide biosynthesis protein A; InterPro IPR013482; KEGG: glo:Glov_0909 molybdopterin-guanine dinucleotide biosynthesis protein A-like protein; SPTR: Probable molybdopterin-guanine dinucleotide biosynthesis protein A 1 YP_004370126.1 COGs: COG0599 gamma-carboxymuconolactone decarboxylase subunit; InterPro IPR003779:IPR004675; KEGG: tbd:Tbd_0657 carboxymuconolactone decarboxylase domain-containing protein; PFAM: Carboxymuconolactone decarboxylase; SPTR: uncharacterized protein; TIGRFAM: Alkylhydroperoxidase AhpD core; PFAM: Carboxymuconolactone decarboxylase; TIGRFAM: alkylhydroperoxidase AhpD family core domain YP_004370127.1 KEGG: dly:Dehly_1058 hypothetical protein; SPTR: uncharacterized protein YP_004370128.1 COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR000644; KEGG: dba:Dbac_1126 signal transduction protein with CBS domains; PFAM: cystathionine beta-synthase, core; SMART: cystathionine beta-synthase, core; SPTR: uncharacterized protein; PFAM: CBS domain YP_004370129.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: afl:Aflv_2118 soluble lytic murein transglycosylase; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Soluble lytic murein transglycosylase and related regulatory proteins (Some contain LysM/invasin domains); PFAM: transglycosylase SLT domain YP_004370130.1 COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: sfu:Sfum_1632 MscS mechanosensitive ion channel; PFAM: Mechanosensitive ion channel MscS; SPTR: MscS Mechanosensitive ion channel; PFAM: Mechanosensitive ion channel YP_004370131.1 COGs: COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); InterPro IPR006668:IPR000644:IPR006667:IPR006669; KEGG: cyt:cce_2010 Mg2+ transporter; PFAM: MgtE magnesium transporter, integral membrane; Magnesium transporter, MgtE intracellular domain; cystathionine beta-synthase, core; SMART: Magnesium transporter, MgtE intracellular domain; cystathionine beta-synthase, core; SPTR: Mg2+ transport protein; TIGRFAM: Divalent cation transporter; PFAM: MgtE intracellular N domain; Divalent cation transporter; CBS domain; TIGRFAM: Mg2+ transporter (mgtE) YP_004370132.1 KEGG: dat:HRM2_32230 hypothetical protein; SPTR: uncharacterized protein YP_004370133.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: lip:LI0888 universal stress protein UspA-like nucleotide-binding protein; PFAM: UspA; SPTR: uncharacterized protein; PFAM: Universal stress protein family YP_004370134.1 KEGG: pat:Patl_1878 LysR family transcriptional regulator; SPTR: uncharacterized protein YP_004370135.1 COGs: COG0215 cysteinyl-tRNA synthetase; InterPro IPR015273:IPR001926:IPR015803:IPR005856; KEGG: dal:Dalk_3820 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; cysteinyl-tRNA synthetase, class Ia; cysteinyl-tRNA synthetase, class Ia, DALR; PRIAM: cysteine synthase., cysteine--tRNA ligase; SMART: cysteinyl-tRNA synthetase, class Ia, DALR; SPTR: cysteine--tRNA ligase; TIGRFAM: cysteine synthase K/M; cysteinyl-tRNA synthetase, class Ia; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthases; cysteinyl-tRNA synthetase; cysteine synthase B YP_004370136.1 COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: dvm:DvMF_3139 cobalt transport protein CbiM; PFAM: Cobalamin (vitamin B12) biosynthesis CbiM; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiM protein; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM YP_004370137.1 KEGG: dde:Dde_1191 hypothetical protein; SPTR: uncharacterized protein YP_004370138.1 COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339:IPR012809; KEGG: dsa:Desal_3207 cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: Cobalt transport protein; SPTR: Cobalt ABC transporter, permease CbiQ; TIGRFAM: Cobalt ABC transporter CbiQ, permease subunit; PFAM: Cobalt transport protein; TIGRFAM: cobalt ABC transporter, permease CbiQ YP_004370139.1 COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: dsa:Desal_3208 ABC transporter related; PFAM: ABC transporter-like; PRIAM: iron ABC transporter ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter YP_004370140.1 KEGG: cak:Caul_4070 hypothetical protein; SPTR: uncharacterized protein YP_004370141.1 KEGG: cyp:PCC8801_3621 hypothetical protein; SPTR: uncharacterized protein YP_004370142.1 COGs: COG5266 ABC-type Co2+ transport system periplasmic component; InterPro IPR019613; KEGG: dol:Dole_2023 hypothetical protein; PFAM: Nickel transport complex, NikM subunit, transmembrane; SPTR: uncharacterized protein; PFAM: Nickel uptake substrate-specific transmembrane region YP_004370143.1 COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: min:Minf_0966 ADP-heptose:LPS heptosyltransferase; PFAM: glycosyl transferase, family 9; SPTR: uncharacterized protein; PFAM: glycosyltransferase 9 (heptosyltransferase) YP_004370144.1 COGs: COG1029 formylmethanofuran dehydrogenase subunit B; KEGG: mma:MM_1980 tungsten formylmethanofuran dehydrogenase, subunit B; PRIAM: formylmethanofuran dehydrogenase; SPTR: Probable tungsten containing formylmethanofuran dehydrogenase, subunit B; TIGRFAM: formylmethanofuran dehydrogenase subunit B YP_004370145.1 COGs: COG1229 formylmethanofuran dehydrogenase subunit A; InterPro IPR013108; KEGG: mmz:MmarC7_1530 amidohydrolase 3; PFAM: Amidohydrolase 3; SPTR: Tungsten formylmethanofuran dehydrogenase subunit A; PFAM: Amidohydrolase YP_004370146.1 InterPro IPR007202:IPR001450; KEGG: mev:Metev_1435 Fe-S cluster domain-containing protein; PFAM: Fe-S cluster; 4Fe-4S binding domain; SPTR: Fe-S cluster domain protein; PFAM: Fe-S cluster YP_004370147.1 COGs: COG1150 Heterodisulfide reductase subunit C; KEGG: dak:DaAHT2_1634 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding; manually curated YP_004370148.1 COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR006076:IPR001450:IPR003953; KEGG: adg:Adeg_1885 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; 4Fe-4S binding domain; FAD dependent oxidoreductase; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: FAD binding domain YP_004370149.1 KEGG: mac:MA2260 hypothetical protein; SPTR: uncharacterized protein YP_004370150.1 KEGG: lsl:LSL_1607 ATP-dependent nuclease subunit A YP_004370151.1 KEGG: dtu:Dtur_1711 hypothetical protein; SPTR: uncharacterized protein YP_004370152.1 COGs: COG0297 glycogen synthase; HAMAP: glycogen/starch synthases, ADP-glucose type; InterPro IPR013534:IPR001296:IPR011835; KEGG: geo:Geob_1010 glycogen/starch synthase, ADP-glucose type; PFAM: Starch synthase, catalytic domain; glycosyl transferase, group 1; PRIAM: Starch synthase; SPTR: glycogen synthase 2; TIGRFAM: glycogen/starch synthases, ADP-glucose type; PFAM: Starch synthase catalytic domain; glycosyl transferases group 1; TIGRFAM: glycogen/starch synthases, ADP-glucose type YP_004370153.1 COGs: COG1432 conserved hypothetical protein; InterPro IPR021139; KEGG: afr:AFE_0663 hypothetical protein; PFAM: Domain of unknown function DUF88; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF88 YP_004370154.1 COGs: COG1420 transcriptional regulator of heat shock gene; HAMAP: Winged helix-turn-helix transcription repressor, HrcA; InterPro IPR021153:IPR002571; KEGG: gsu:GSU0031 heat-inducible transcription repressor HrcA; PFAM: Winged helix-turn-helix transcription repressor, HrcA, C-terminal; SPTR: Heat-inducible transcription repressor hrcA; TIGRFAM: Winged helix-turn-helix transcription repressor, HrcA; PFAM: HrcA protein C terminal domain; TIGRFAM: heat shock gene repressor HrcA YP_004370155.1 COGs: COG0576 Molecular chaperone GrpE (heat shock protein); HAMAP: GrpE nucleotide exchange factor; InterPro IPR000740; KEGG: sfu:Sfum_1035 GrpE protein; PFAM: GrpE nucleotide exchange factor; SPTR: protein grpE; PFAM: GrpE YP_004370156.1 COGs: COG0443 Molecular chaperone; HAMAP: Chaperone DnaK; InterPro IPR013126:IPR012725; KEGG: sat:SYN_01983 chaperone protein; PFAM: Heat shock protein 70; SPTR: Chaperone protein dnaK 1; TIGRFAM: Chaperone DnaK; PFAM: Hsp70 protein; TIGRFAM: chaperone protein DnaK YP_004370157.1 COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: dal:Dalk_3701 extracellular ligand-binding receptor; PFAM: Extracellular ligand-binding receptor; SPTR: Extracellular ligand-binding receptor; PFAM: LppC lipoprotein YP_004370158.1 COGs: COG3191 L-aminopeptidase/D-esterase; InterPro IPR005321; KEGG: sus:Acid_0583 peptidase S58, DmpA; PFAM: peptidase S58, DmpA; SPTR: peptidase S58, DmpA; PFAM: peptidase S58 YP_004370159.1 KEGG: mpt:Mpe_A3768 hypothetical protein; SPTR: uncharacterized protein YP_004370160.1 COGs: COG0370 Fe2+ transport system protein B; InterProIPR002917:IPR011619:IPR011642:IPR011640:IPR 005225:IPR003373; KEGG: dal:Dalk_1642 ferrous iron transport protein B; PFAM: Ferrous iron transport protein B, N-terminal; GTP-binding protein, HSR1-related; nucleoside recognition; Ferrous iron transport protein B, C-terminal; SPTR: Ferrous iron transport protein B; TIGRFAM: Ferrous iron transport protein B; Small GTP-binding protein; PFAM: Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB; small GTP-binding protein domain YP_004370161.1 COGs: COG1918 Fe2+ transport system protein A; InterPro IPR007167; KEGG: tpe:Tpen_0974 FeoA family protein; PFAM: Ferrous iron transporter, FeoA subunit; SMART: Ferrous iron transporter, FeoA subunit; SPTR: Ferrous iron transport protein B; PFAM: FeoA domain YP_004370162.1 COGs: COG1363 Cellulase M and related protein; InterPro IPR008007; KEGG: amu:Amuc_1103 glutamyl aminopeptidase; PFAM: peptidase M42; PRIAM: Cellulase; SPTR: glutamyl aminopeptidase; PFAM: M42 glutamyl aminopeptidase YP_004370163.1 InterPro IPR000620; KEGG: rsc:RCFBP_20103 small multidrug resistance transmembrane protein; PFAM: Drug/metabolite transporter; SPTR: membrane protein; PFAM: EamA-like transporter family YP_004370164.1 KEGG: npu:Npun_F1577 exonuclease SbcC; SPTR: Coiled-coil domain containing 21-like protein YP_004370165.1 COGs: COG0218 GTPase; HAMAP: GTP-binding protein, ribosome biogenesis, YsxC; InterPro IPR002917:IPR019987; KEGG: gbm:Gbem_3815 ribosome biogenesis GTP-binding protein YsxC; PFAM: GTP-binding protein, HSR1-related; SPTR: Probable GTP-binding protein engB; TIGRFAM: GTP-binding protein, ribosome biogenesis, YsxC; PFAM: GTPase of unknown function; TIGRFAM: ribosome biogenesis GTP-binding protein YsxC/EngB YP_004370166.1 KEGG: mpr:MPER_11193 hypothetical protein; SPTR: uncharacterized protein YP_004370167.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR006158:IPR007197; KEGG: sat:SYN_02176 Fe-S oxidoreductase; PFAM: Radical SAM; Cobalamin (vitamin B12)-binding; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; PFAM: Radical SAM superfamily; B12 binding domain YP_004370168.1 KEGG: noc:Noc_0662 hypothetical protein; SPTR: uncharacterized protein YP_004370169.1 KEGG: mgi:Mflv_2879 hypothetical protein; SPTR: uncharacterized protein YP_004370170.1 COGs: COG0328 ribonuclease HI; HAMAP: ribonuclease H; InterPro IPR002156:IPR022892; KEGG: cyh:Cyan8802_4434 ribonuclease H; PFAM: ribonuclease H domain; PRIAM: ribonuclease H; SPTR: ribonuclease H; PFAM: RNase H YP_004370171.1 COGs: COG2043 conserved hypothetical protein; InterPro IPR003748; KEGG: drm:Dred_2869 hypothetical protein; PFAM: protein of unknown function DUF169; SPTR: uncharacterized protein; PFAM: Uncharacterised ArCR, COG2043 YP_004370172.1 KEGG: dal:Dalk_2527 hypothetical protein; SPTR: uncharacterized protein YP_004370173.1 InterPro IPR002781; KEGG: dal:Dalk_2526 protein of unknown function DUF81; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004370174.1 COGs: COG3829 transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR000014:IPR003593:IPR013767:IPR002078:IPR 002197; KEGG: dal:Dalk_4236 PAS modulated sigma54 specific transcriptional regulator, Fis family; PFAM: RNA polymerase sigma factor 54, interaction; PAS fold; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; PAS; SPTR: PAS domain S-box protein; TIGRFAM: PAS; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; PAS fold; TIGRFAM: PAS domain S-box YP_004370175.1 COGs: COG3221 ABC-type phosphate/phosphonate transport system periplasmic component; InterPro IPR005770; KEGG: drt:Dret_0228 phosphonate ABC transporter, periplasmic phosphonate-binding protein; SPTR: phosphonate ABC transporter, periplasmic phosphonate-binding protein; TIGRFAM: phosphonate-binding periplasmic protein; TIGRFAM: phosphate/phosphite/phosphonate ABC transporters, periplasmic binding protein YP_004370176.1 COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR003661:IPR003594:IPR003660:IPR013656:IPR 000014; KEGG: drt:Dret_0229 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004370177.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dma:DMR_38710 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain YP_004370178.1 COGs: COG0574 phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279; KEGG: dde:Dde_0604 pyruvate,water dikinase; PFAM: pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile domain; PRIAM: pyruvate, water dikinase; SPTR: pyruvate water dikinase; PFAM: PEP-utilising enzyme, mobile domain; pyruvate phosphate dikinase, PEP/pyruvate binding domain YP_004370179.1 KEGG: gvg:HMPREF0421_20395 dihydroorotate oxidase; SPTR: Possible dihydroorotate oxidase YP_004370180.1 COGs: COG0627 esterase; InterPro IPR000801; KEGG: sli:Slin_3361 esterase; PFAM: esterase; SPTR: esterase superfamily protein; PFAM: esterase YP_004370181.1 COGs: COG0824 thioesterase; InterPro IPR006683:IPR006684; KEGG: fpl:Ferp_1466 4-hydroxybenzoyl-CoA thioesterase; PFAM: Thioesterase superfamily; SPTR: 4-hydroxybenzoyl-CoA thioesterase; TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase; PFAM: Thioesterase superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family YP_004370182.1 KEGG: sfu:Sfum_1264 hypothetical protein; SPTR: uncharacterized protein YP_004370183.1 COGs: COG0775 nucleoside phosphorylase; InterPro IPR000845; KEGG: gme:Gmet_1274 purine phosphorylase 1; PFAM: nucleoside phosphorylase domain; SPTR: Purine and other phosphorylases, family 1; PFAM: phosphorylase superfamily YP_004370184.1 InterPro IPR007354; KEGG: sfu:Sfum_0866 hypothetical protein; PFAM: protein of unknown function DUF422; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF422) YP_004370185.1 COGs: COG0761 Penicillin tolerance protein; HAMAP: LytB protein; InterPro IPR003451:IPR000537; KEGG: dol:Dole_0383 hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; UbiA prenyltransferase; PRIAM: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; SPTR: uncharacterized protein; TIGRFAM: LytB protein; PFAM: LytB protein; UbiA prenyltransferase; TIGRFAM: (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming) YP_004370186.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: sat:SYN_01128 nucleotide-sugar aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; PRIAM: glutamine--scyllo-inositol transaminase; SPTR: nucleotide-sugar aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase YP_004370187.1 COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: nwa:Nwat_2849 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: dTDP-glucose 4,6-dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase YP_004370188.1 COGs: COG0574 phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279:IPR000121:IPR010121; KEGG: slt:Slit_0924 pyruvate, phosphate dikinase; PFAM: pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme; PRIAM: pyruvate, phosphate dikinase; SPTR: pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: pyruvate, phosphate dikinase YP_004370189.1 KEGG: sha:SH2670 hypothetical protein; SPTR: P450 monooxygenase for C-4 hydroxylation of trichothecene YP_004370190.1 COGs: COG0474 Cation transport ATPase; InterProIPR004014:IPR008250:IPR005834:IPR006068:IPR 001757; KEGG: rca:Rcas_0372 HAD superfamily ATPase; PFAM: ATPase, P-type, ATPase-associated domain; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase; ATPase, P-type cation-transporter, C-terminal; PRIAM: Calcium-transporting ATPase; SMART: ATPase, P-type cation-transporter, N-terminal; SPTR: ATPase, P-type (transporting), HAD superfamily, subfamily IC; TIGRFAM: ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehalogenase-like hydrolase; TIGRFAM: plasma-membrane calcium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; potassium and/or sodium efflux P-type ATPase, fungal-type YP_004370191.1 COGs: COG1189 rRNA methylase; InterPro IPR002942:IPR002877:IPR004538; KEGG: gbm:Gbem_2654 rRNA methyltransferase, YqxC-like; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4; SMART: RNA-binding S4; SPTR: rRNA methyltransferase, YqxC-related, ; TIGRFAM: Haemolysin A; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein YP_004370192.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: dbr:Deba_0845 two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004370193.1 COGs: COG0421 Spermidine synthase; InterPro IPR001045; KEGG: sfu:Sfum_1994 spermidine synthase; PFAM: Spermine synthase; SPTR: Spermidine synthase; PFAM: Spermine/spermidine synthase YP_004370194.1 KEGG: sfu:Sfum_1300 hypothetical protein; SPTR: uncharacterized protein YP_004370195.1 COGs: COG0558 phosphatidylglycerophosphate synthase; InterPro IPR000462:IPR004570; KEGG: sat:SYN_01716 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_004370196.1 COGs: COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; HAMAP: tRNA delta(2)-isopentenylpyrophosphate transferase; InterPro IPR002627:IPR018022; KEGG: sfu:Sfum_1920 tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; PRIAM: tRNA isopentenyltransferase; SPTR: tRNA dimethylallyltransferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: IPP transferase; TIGRFAM: tRNA dimethylallyltransferase YP_004370197.1 InterPro IPR003848; KEGG: rru:Rru_A2551 hypothetical protein; PFAM: Domain of unknown function DUF218; SPTR: uncharacterized protein; PFAM: DUF218 domain YP_004370198.1 COGs: COG1859 RNA:NAD 2'-phosphotransferase; InterPro IPR002745; KEGG: dol:Dole_1544 phosphotransferase KptA/Tpt1; PFAM: phosphotransferase KptA/Tpt1; SPTR: phosphotransferase KptA/Tpt1; PFAM: RNA 2'-phosphotransferase, Tpt1 / KptA family YP_004370199.1 KEGG: dat:HRM2_30630 hypothetical protein; SPTR: uncharacterized protein YP_004370200.1 COGs: COG2331 conserved hypothetical protein; InterPro IPR013429; KEGG: dat:HRM2_30620 FmdB family protein (regulatory protein); PFAM: Regulatory protein, FmdB, SMART: Regulatory protein, FmdB, SPTR: FmdB family protein (Regulatory protein); TIGRFAM: Regulatory protein, FmdB, PFAM: Zinc ribbon domain; TIGRFAM: regulatory protein, FmdB family YP_004370201.1 KEGG: adg:Adeg_1791 hypothetical protein; SPTR: uncharacterized protein YP_004370202.1 COGs: COG1504 conserved hypothetical protein; InterPro IPR007523; KEGG: adg:Adeg_1298 protein of unknown function DUF498; PFAM: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF498/DUF598) YP_004370203.1 COGs: COG0565 rRNA methylase; InterPro IPR001537:IPR004384; KEGG: sfu:Sfum_1297 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase, SpoU; SPTR: RNA methyltransferase, TrmH family, group 1; TIGRFAM: RNA methyltransferase TrmH, group 1; PFAM: SpoU rRNA methylase; TIGRFAM: RNA methyltransferase, TrmH family, group 1 YP_004370205.1 COGs: COG1042 acyl-CoA synthetase (NDP forming); InterPro IPR003781; KEGG: sfu:Sfum_0708 CoA-binding domain-containing protein; PFAM: CoA-binding; SMART: CoA-binding; SPTR: CoA-binding domain protein; PFAM: CoA binding domain YP_004370206.1 COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027:IPR001678:IPR004573; KEGG: dol:Dole_2231 sun protein; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; NusB/RsmB/TIM44; SPTR: Sun protein; TIGRFAM: Fmu, rRNA SAM-dependent methyltransferase; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB YP_004370207.1 COGs: COG1852 conserved hypothetical protein; InterPro IPR002829; KEGG: gsu:GSU0131 hypothetical protein; PFAM: protein of unknown function DUF116; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF116 YP_004370208.1 COGs: COG0223 methionyl-tRNA formyltransferase; HAMAP: methionyl-tRNA formyltransferase; InterPro IPR002376:IPR005793:IPR005794; KEGG: nde:NIDE0395 methionyl-tRNA formyltransferase; PFAM: formyl transferase, N-terminal; formyl transferase, C-terminal; PRIAM: methionyl-tRNA formyltransferase; SPTR: methionyl-tRNA formyltransferase; TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase; formyl transferase, C-terminal domain; TIGRFAM: methionyl-tRNA formyltransferase YP_004370209.1 COGs: COG0242 N-formylmethionyl-tRNA deformylase; HAMAP: formylmethionine deformylase; InterPro IPR000181; KEGG: tye:THEYE_A0329 peptide deformylase; PFAM: formylmethionine deformylase; SPTR: peptide deformylase; TIGRFAM: formylmethionine deformylase; PFAM: polypeptide deformylase; TIGRFAM: peptide deformylase YP_004370210.1 COGs: COG0450 Peroxiredoxin; InterPro IPR000866; KEGG: dal:Dalk_1204 alkyl hydroperoxide reductase; PFAM: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; SPTR: Alkyl hydroperoxide reductase; PFAM: AhpC/TSA family YP_004370211.1 COGs: COG0450 Peroxiredoxin; InterPro IPR000866; KEGG: dat:HRM2_32850 PrxU; PFAM: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; SPTR: PrxU; PFAM: AhpC/TSA family YP_004370212.1 COGs: COG0753 Catalase; InterPro IPR018028:IPR010582; KEGG: dbr:Deba_0799 catalase; PFAM: Catalase-related subgroup; Catalase-related immune responsive; PRIAM: Catalase; SPTR: Catalase; PFAM: Catalase; Catalase-related immune-responsive YP_004370213.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: sfu:Sfum_1722 ferric uptake regulator family protein; PFAM: Ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family YP_004370214.1 InterPro IPR002559; KEGG: app:CAP2UW1_3182 transposase IS4 family protein; PFAM: transposase, IS4-like; SPTR: transposase IS4 family protein; PFAM: transposase DDE domain YP_004370215.1 COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: sfu:Sfum_2592 rod shape-determining protein MreB; PFAM: Cell shape determining protein MreB/Mrl; SPTR: Cell division protein FtsA; TIGRFAM: Cell shape determining protein MreB/Mrl; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family YP_004370216.1 COGs: COG1792 Cell shape-determining protein; InterPro IPR007221:IPR005223; KEGG: gur:Gura_2860 rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: Rod shape-determining protein MreC; TIGRFAM: Rod shape-determining protein MreC, subtype; PFAM: rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC YP_004370217.1 KEGG: pca:Pcar_1047 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: rod shape-determining protein MreD YP_004370218.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460:IPR017790; KEGG: dbr:Deba_0280 penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding protein dimerisation domain; TIGRFAM: penicillin-binding protein 2 YP_004370219.1 COGs: COG2518 protein-L-isoaspartate carboxylmethyltransferase; HAMAP: protein-L-isoaspartate(D-aspartate) O-methyltransferase; InterPro IPR000682; KEGG: sfu:Sfum_2480 protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; PRIAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; SPTR: protein-L-isoaspartate O-methyltransferase 1; TIGRFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); TIGRFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_004370220.1 COGs: COG0269 3-hexulose-6-phosphate synthase and related protein; InterPro IPR001754:IPR005493; KEGG: abi:Aboo_0457 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase domain; ribonuclease E inhibitor RraA/Dimethylmenaquinone methyltransferase; PRIAM: 3-hexulose-6-phosphate synthase; SMART: Orotidine 5'-phosphate decarboxylase domain; SPTR: Thiamine monophosphate synthase/TENI subfamily, ; PFAM: Demethylmenaquinone methyltransferase; Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: 3-hexulose-6-phosphate synthase YP_004370221.1 COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR001347; KEGG: ton:TON_0336 bifunctional D-arabino 3-hexulose-6-phosphate formaldehyde lyase/phosphohexuloisomerase; PFAM: Sugar isomerase (SIS); PRIAM: 6-phospho-3-hexuloisomerase; SPTR: 3-hexulose-6-phosphate isomerase; PFAM: SIS domain; TIGRFAM: 6-phospho 3-hexuloisomerase YP_004370222.1 KEGG: hth:HTH_1490 hypothetical protein; SPTR: uncharacterized protein YP_004370223.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279; KEGG: sfu:Sfum_1732 beta-lactamase domain-containing protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily YP_004370225.1 COGs: COG0474 Cation transport ATPase; InterProIPR004014:IPR008250:IPR005834:IPR006534:IPR 001757; KEGG: hna:Hneap_0971 plasma-membrane proton-efflux P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase; PRIAM: Proton-exporting ATPase; SMART: ATPase, P-type cation-transporter, N-terminal; SPTR: Plasma-membrane proton-efflux P-type ATPase; TIGRFAM: ATPase, P-type, plasma-membrane proton-efflux; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; PFAM: E1-E2 ATPase; Cation transporter/ATPase, N-terminus; haloacid dehalogenase-like hydrolase; TIGRFAM: plasma-membrane proton-efflux P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004370226.1 COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR010206; KEGG: dbr:Deba_0868 poly(A) polymerase; PFAM: poly A polymerase, head domain; PRIAM: polynucleotide adenylyltransferase; SPTR: poly(A) polymerase, PcnB; TIGRFAM: poly(A) polymerase, PcnB; PFAM: poly A polymerase head domain; TIGRFAM: poly(A) polymerase YP_004370227.1 KEGG: dhd:Dhaf_3159 hypothetical protein; SPTR: uncharacterized protein YP_004370228.1 COGs: COG0730 permease; InterPro IPR002781; KEGG: dds:Ddes_0357 protein of unknown function DUF81; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004370229.1 COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: dma:DMR_27000 phenylacetate-coenzyme A ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Phenylacetate--CoA ligase; SPTR: Phenylacetate--CoA ligase; PFAM: AMP-binding enzyme YP_004370230.1 InterPro IPR013990; KEGG: ade:Adeh_0384 hypothetical protein; SMART: Water stress and hypersensitive response domain; SPTR: uncharacterized protein; PFAM: Late embryogenesis abundant protein YP_004370231.1 InterPro IPR018550; KEGG: cpb:Cphamn1_1824 hypothetical protein; PFAM: Lipid A 3-O-deacylase-related; SPTR: uncharacterized protein; PFAM: Lipid A 3-O-deacylase (PagL) YP_004370232.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: sfu:Sfum_2668 ferric uptake regulator family protein; PFAM: Ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family YP_004370233.1 COGs: COG0571 dsRNA-specific ribonuclease; HAMAP: ribonuclease III, bacterial; InterPro IPR000999:IPR001159:IPR011907; KEGG: dbr:Deba_0715 ribonuclease III; PFAM: ribonuclease III; Double-stranded RNA-binding; PRIAM: ribonuclease III; SMART: ribonuclease III; Double-stranded RNA-binding; SPTR: ribonuclease III; TIGRFAM: ribonuclease III, bacterial; PFAM: RNase3 domain; Double-stranded RNA binding motif; TIGRFAM: ribonuclease III, bacterial YP_004370234.1 COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR000064; KEGG: pjd:Pjdr2_0116 NLP/P60 protein; PFAM: NLP/P60; SPTR: NLP/P60 protein; PFAM: NlpC/P60 family YP_004370235.1 KEGG: dbr:Deba_2143 hypothetical protein; SPTR: uncharacterized protein YP_004370236.1 InterPro IPR004300; KEGG: cag:Cagg_2093 glycoside hydrolase 57; PFAM: glycoside hydrolase, family 57, N-terminal; SPTR: glycoside hydrolase 57; PFAM: glycosyl hydrolase 57; Domain of unknown function (DUF3536) YP_004370237.1 KEGG: sfu:Sfum_1279 hypothetical protein; SPTR: uncharacterized protein; PFAM: 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) YP_004370238.1 COGs: COG1926 phosphoribosyltransferase; InterPro IPR000836; KEGG: pmx:PERMA_0016 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: uncharacterized protein; PFAM: phosphoribosyl transferase domain YP_004370240.1 KEGG: dat:HRM2_13480 hypothetical protein; SPTR: uncharacterized protein YP_004370241.1 COGs: COG4206 Outer membrane cobalamin receptor protein; InterPro IPR012910:IPR000531; KEGG: dat:HRM2_13410 TonB-like outer membrane receptor protein; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: TonB-like outer membrane receptor protein; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004370242.1 COGs: COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A); InterPro IPR000440; KEGG: sfu:Sfum_0199 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase, chain 3; SPTR: NADH-quinone oxidoreductase subunit; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 YP_004370243.1 COGs: COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductase; HAMAP: NADH-ubiquinone oxidoreductase, 20 Kd subunit; InterPro IPR006137:IPR006138; KEGG: dak:DaAHT2_1929 NADH-quinone oxidoreductase, B subunit; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase subunit B; TIGRFAM: NADH-ubiquinone oxidoreductase, 20 Kd subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit YP_004370244.1 COGs: COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; InterPro IPR001268; KEGG: dak:DaAHT2_1928 NADH dehydrogenase (ubiquinone) 30 kDa subunit; PFAM: NADH:ubiquinone oxidoreductase, 30kDa subunit; SPTR: NADH dehydrogenase (Ubiquinone) 30 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit YP_004370245.1 COGs: COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7; HAMAP: NAD(P)H-quinone oxidoreductase subunit D/H; InterPro IPR001135:IPR022885; KEGG: sfu:Sfum_0202 NADH dehydrogenase (ubiquinone); PFAM: NADH-quinone oxidoreductase, subunit D; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase subunit D; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit YP_004370246.1 COGs: COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); InterPro IPR001694; KEGG: sfu:Sfum_0203 respiratory-chain NADH dehydrogenase, subunit 1; PFAM: NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase subunit H 1; PFAM: NADH dehydrogenase YP_004370247.1 COGs: COG1143 formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); HAMAP: NADH-quinone oxidoreductase, chain I; InterPro IPR001450:IPR010226; KEGG: dak:DaAHT2_1925 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase subunit I 1; TIGRFAM: NADH-quinone oxidoreductase, chain I; PFAM: 4Fe-4S binding domain; TIGRFAM: NADH-quinone oxidoreductase, chain I YP_004370248.1 COGs: COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J); InterPro IPR001457; KEGG: sfu:Sfum_0205 NADH-ubiquinone/plastoquinone oxidoreductase, chain 6; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase, chain 6; SPTR: NADH-ubiquinone/plastoquinone oxidoreductase, chain 6; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6 YP_004370249.1 COGs: COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); HAMAP: NADH-ubiquinone oxidoreductase chain 4L/K; InterPro IPR001133; KEGG: dak:DaAHT2_1923 NADH-ubiquinone oxidoreductase chain 4L; PFAM: NADH-ubiquinone oxidoreductase chain 4L/K; SPTR: NADH-quinone oxidoreductase subunit K; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L YP_004370250.1 COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR001516:IPR001750:IPR003945; KEGG: sfu:Sfum_0207 proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; NADH:ubiquinone oxidoreductase, chain 5/L, N-terminal; PRIAM: NADH dehydrogenase (quinone); SPTR: Proton-translocating NADH-quinone oxidoreductase, chain L; TIGRFAM: NADH-plastoquinone oxidoreductase, chain 5; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L YP_004370251.1 COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR001750:IPR010227; KEGG: sfu:Sfum_1936 proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: Proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: NADH-quinone oxidoreductase, chain M/4; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M YP_004370252.1 COGs: COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); HAMAP: NAD(P)H-quinone oxidoreductase, subunit N/subunit 2; InterPro IPR001750:IPR010096; KEGG: sfu:Sfum_0209 proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase subunit N 1; TIGRFAM: NAD(P)H-quinone oxidoreductase, subunit N/subunit 2; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N YP_004370253.1 COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: sfu:Sfum_3407 dinitrogenase iron-molybdenum cofactor biosynthesis; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; SPTR: Dinitrogenase iron-molybdenum cofactor biosynthesis; PFAM: Dinitrogenase iron-molybdenum cofactor YP_004370254.1 COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871; KEGG: dbr:Deba_2174 nitrogen-fixing NifU domain protein; PFAM: NIF system FeS cluster assembly, NifU, N-terminal; SPTR: nitrogen-fixing NifU domain protein; PFAM: NifU-like N terminal domain YP_004370255.1 KEGG: sfu:Sfum_3406 response regulator receiver protein; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain YP_004370256.1 InterPro IPR018660; KEGG: yen:YE2141 lipoprotein; PFAM: protein of unknown function DUF2091, periplasmic; SPTR: uncharacterized protein; PFAM: Membrane-bound lysozyme-inhibitor of c-type lysozyme YP_004370257.1 COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR003660:IPR003661:IPR003594; KEGG: dvl:Dvul_0091 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: uncharacterized protein; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004370258.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: dbr:Deba_0035 two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: Acetoacetate metabolism regulatory protein atoC; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004370259.1 COGs: COG0466 ATP-dependent Lon protease; InterPro IPR001789:IPR003593:IPR003959:IPR008269; KEGG: tye:THEYE_A0758 ATP-dependent protease La 1; PFAM: peptidase S16, Lon C-terminal; ATPase, AAA-type, core; Signal transduction response regulator, receiver domain; PRIAM: Endopeptidase La; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: ATP-dependent protease La 2; PFAM: Response regulator receiver domain; ATPase associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La YP_004370260.1 KEGG: tye:THEYE_A0760 hypothetical protein; SPTR: uncharacterized protein YP_004370261.1 COGs: COG0730 permease; InterPro IPR002781; KEGG: dvm:DvMF_2103 protein of unknown function DUF81; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004370262.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: tye:THEYE_A0762 universal stress protein, PFAM: UspA; SPTR: Universal stress protein, ; PFAM: Universal stress protein family YP_004370263.1 COGs: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); InterPro IPR007197; KEGG: sfu:Sfum_2456 radical SAM domain-containing protein; PFAM: Radical SAM; SPTR: radical SAM protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM additional 4Fe4S-binding domain YP_004370264.1 KEGG: pca:Pcar_3203 hypothetical protein; SPTR: uncharacterized protein YP_004370265.1 COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160; KEGG: gau:GAU_0485 two-component response regulator; PFAM: Diguanylate cyclase, predicted; PRIAM: Diguanylate kinase; SMART: Diguanylate cyclase, predicted; SPTR: two-component response regulator; TIGRFAM: Diguanylate cyclase, predicted; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004370266.1 COGs: COG4113 nucleic acid-binding protein contains PIN domain; InterPro IPR002716; KEGG: rmr:Rmar_2863 twitching mobility protein PilT; PFAM: PilT protein, N-terminal; SPTR: twitching mobility protein PilT; PFAM: PIN domain YP_004370267.1 InterPro IPR006442; KEGG: tth:TTC1805 hypothetical protein; PFAM: Prevent-host-death protein; SPTR: uncharacterized protein; TIGRFAM: Prevent-host-death protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein YP_004370268.1 KEGG: tet:TTHERM_00842700 ubiquitin-transferase, HECT-domain; SPTR: Chromosome undetermined SCAF11462, whole genome shotgun sequence YP_004370269.1 SPTR: Chromosome 14 SCAF15003, whole genome shotgun sequence. YP_004370270.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910:IPR000531; KEGG: ppd:Ppro_1253 TonB-dependent receptor, plug; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: TonB-dependent receptor, plug; PFAM: TonB-dependent Receptor Plug Domain YP_004370271.1 COGs: COG2875 Precorrin-4 methylase; InterPro IPR000878; KEGG: dae:Dtox_0475 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases YP_004370273.1 InterPro IPR000835; KEGG: dbr:Deba_1190 transcriptional regulator, MarR family; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: transcriptional regulator, MarR family; PFAM: MarR family YP_004370274.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: sfu:Sfum_3680 secretion protein HlyD family protein; PFAM: Secretion protein HlyD; SPTR: Secretion protein HlyD family protein; TIGRFAM: Secretion protein HlyD; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004370275.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036:IPR004764; KEGG: dol:Dole_2895 hydrophobe/amphiphile efflux-1 (HAE1) family protein; PFAM: Acriflavin resistance protein; SPTR: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family YP_004370276.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423:IPR010131; KEGG: sfu:Sfum_3678 outer membrane efflux protein; PFAM: Outer membrane efflux protein; SPTR: Outer membrane efflux protein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT; PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family YP_004370277.1 COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: ctc:CTC01320 GufA protein; PFAM: Zinc/iron permease; SPTR: GufA protein; PFAM: ZIP Zinc transporter YP_004370278.1 KEGG: ppp:PHYPADRAFT_74011 hypothetical protein YP_004370279.1 COGs: COG0531 Amino acid transporter; InterPro IPR004841; KEGG: ppd:Ppro_1252 amino acid permease-associated region; PFAM: Amino acid permease domain; SPTR: Amino acid permease-associated region; PFAM: Amino acid permease YP_004370280.1 COGs: COG2875 Precorrin-4 methylase; InterPro IPR000878; KEGG: dae:Dtox_0475 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases YP_004370281.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910; KEGG: mpt:Mpe_A2804 outer membrane receptor protein; PFAM: TonB-dependent receptor, plug; SPTR: Outer membrane receptor protein; PFAM: TonB-dependent Receptor Plug Domain YP_004370282.1 COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260; KEGG: ppd:Ppro_1236 TonB family protein; PFAM: TonB, C-terminal; SPTR: TonB family protein; TIGRFAM: TonB, C-terminal; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain YP_004370283.1 COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: bba:Bd0478 TonB system transport protein ExbD2; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: uncharacterized protein; PFAM: Biopolymer transport protein ExbD/TolR YP_004370284.1 COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: afw:Anae109_0873 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: uncharacterized protein; PFAM: MotA/TolQ/ExbB proton channel family YP_004370285.1 COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR022689:IPR022687:IPR001367; KEGG: dps:DP2966 iron-dependent repressor; PFAM: Iron dependent repressor; Iron dependent repressor, N-terminal; SMART: Iron dependent repressor, diptheria toxin type; SPTR: uncharacterized protein; PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain YP_004370286.1 InterPro IPR000835; KEGG: dbr:Deba_1190 transcriptional regulator, MarR family; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: transcriptional regulator, MarR family; PFAM: MarR family YP_004370287.1 COGs: COG1214 Inactive homolog of metal-dependent protease molecular chaperone; InterPro IPR022496:IPR000905; KEGG: sfu:Sfum_1786 peptidase M22, glycoprotease; PFAM: peptidase M22, glycoprotease; SPTR: peptidase M22, glycoprotease; TIGRFAM: Conserved hypothetical protein CHP03725, YeaZ; PFAM: glycoprotease; TIGRFAM: universal bacterial protein YeaZ YP_004370288.1 COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: sfu:Sfum_0861 inner-membrane translocator; PFAM: ABC transporter permease; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component YP_004370289.1 COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: sfu:Sfum_0858 inner-membrane translocator; PFAM: ABC transporter permease; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component YP_004370290.1 COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: mta:Moth_2499 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004370291.1 COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: tnp:Tnap_1626 ABC transporter; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Branched chain amino acid ABC transporter, ATP-binding protein; PFAM: ABC transporter YP_004370292.1 COGs: COG2453 protein-tyrosine phosphatase; InterPro IPR020422:IPR000340; KEGG: dba:Dbac_1987 dual specificity protein phosphatase; PFAM: Dual specificity phosphatase, catalytic domain; SMART: Dual specificity phosphatase, subgroup, catalytic domain; SPTR: Dual specificity protein phosphatase; PFAM: Dual specificity phosphatase, catalytic domain YP_004370293.1 InterPro IPR001450; KEGG: gsu:GSU3187 ferredoxin family protein; PFAM: 4Fe-4S binding domain; SPTR: Ferredoxin family protein; PFAM: 4Fe-4S binding domain YP_004370294.1 KEGG: nfa:nfa10270 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) YP_004370295.1 COGs: COG1944 conserved hypothetical protein; InterPro IPR019734:IPR003776:IPR001440; KEGG: sfu:Sfum_0413 hypothetical protein; PFAM: YcaO-like; Tetratricopeptide TPR-1; SPTR: Uncharacterized domain; TIGRFAM: YcaO-like; PFAM: YcaO-like family; Tetratricopeptide repeat; TIGRFAM: uncharacterized domain; bacteriocin biosynthesis docking scaffold, SagD family YP_004370296.1 KEGG: sfu:Sfum_3772 hypothetical protein; SPTR: uncharacterized protein YP_004370297.1 COGs: COG1341 GTPase or GTP-binding protein; KEGG: adg:Adeg_0989 GTPase or GTP-binding protein-like protein; SPTR: GTPase or GTP-binding protein-like protein YP_004370298.1 COGs: COG0778 nitroreductase; InterPro IPR000415; KEGG: sat:SYN_01811 nitrobenzoate nitroreductase; PFAM: nitroreductase-like; SPTR: nitrobenzoate nitroreductase; PFAM: nitroreductase YP_004370299.1 KEGG: sat:SYN_02712 hypothetical protein; SPTR: Hypothetical membrane protein; PFAM: protein of unknown function (DUF3568) YP_004370300.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: pca:Pcar_1256 dehydrogenase; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; SPTR: uncharacterized protein; PFAM: Oxidoreductase, NAD-binding Rossmann fold; Oxidoreductase, C-terminal alpha/beta domain YP_004370301.1 COGs: COG0763 Lipid A disaccharide synthetase; HAMAP: glycosyl transferase, family 19; InterPro IPR003835; KEGG: sat:SYN_01565 lipid-A-disaccharide synthase; PFAM: glycosyl transferase, family 19; PRIAM: Lipid-A-disaccharide synthase; SPTR: Lipid-A-disaccharide synthase; TIGRFAM: glycosyl transferase, family 19; PFAM: Lipid-A-disaccharide synthetase; TIGRFAM: lipid-A-disaccharide synthase YP_004370302.1 COGs: COG1830 DhnA-type fructose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: dma:DMR_42330 fructose-bisphosphate aldolase; PFAM: Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; SPTR: Fructose-bisphosphate aldolase class I; PFAM: DeoC/LacD family aldolase YP_004370303.1 COGs: COG0365 acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: sfu:Sfum_2077 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Acetate--CoA ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme YP_004370304.1 COGs: COG2199 FOG: GGDEF domain; InterProIPR000014:IPR001610:IPR003018:IPR000160:IPR 013655:IPR013767; KEGG: cyj:Cyan7822_3932 PAS/PAC and GAF sensors-containing diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; PAS fold-3; PAS fold; GAF; PRIAM: Diguanylate kinase; SMART: Diguanylate cyclase, predicted; PAS; PAC motif; GAF; SPTR: PAS fold family; TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: GGDEF domain; protein of unknown function (DUF3365); PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain YP_004370305.1 COGs: COG0730 permease; InterPro IPR002781; KEGG: dvm:DvMF_0703 protein of unknown function DUF81; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004370306.1 InterPro IPR019088; KEGG: dae:Dtox_0968 hypothetical protein; PFAM: Conserved hypothetical protein CHP02186-related, transmembrane; SPTR: uncharacterized protein; PFAM: transmembrane protein (Alph_Pro_TM); TIGRFAM: conserved hypothetical protein YP_004370307.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: rso:RSc0184 hypothetical protein; PFAM: UspA; SPTR: UspA domain protein; PFAM: Universal stress protein family YP_004370308.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623; KEGG: sua:Saut_1418 heat shock protein DnaJ domain-containing protein; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Heat shock protein DnaJ domain protein; PFAM: DnaJ domain YP_004370309.1 KEGG: pca:Pcar_1660 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3108) YP_004370310.1 KEGG: srm:PSR_11004 hypothetical protein; SPTR: Prophage MuMc02, terminase, ATPase subunit, ; PFAM: Terminase-like family YP_004370311.1 KEGG: aba:Acid345_2065 hypothetical protein; SPTR: uncharacterized protein YP_004370312.1 COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789:IPR000160; KEGG: nmu:Nmul_A0335 response regulator receiver/GGDEF/EAL domain-containing protein; PFAM: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver domain; SMART: Diguanylate cyclase, predicted; Signal transduction response regulator, receiver domain; SPTR: Diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004370313.1 COGs: COG0021 transketolase; InterPro IPR005475:IPR005478:IPR005474:IPR005476; KEGG: pna:Pnap_4499 transketolase; PFAM: transketolase, N-terminal; transketolase-like, pyrimidine-binding domain; transketolase, C-terminal; PRIAM: formaldehyde transketolase; SMART: transketolase-like, pyrimidine-binding domain; SPTR: transketolase; TIGRFAM: transketolase, bacterial-like; PFAM: transketolase, thiamine diphosphate binding domain; transketolase, C-terminal domain; transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast YP_004370314.1 KEGG: dau:Daud_0708 DNA methylase N-4/N-6 domain-containing protein; SPTR: DNA methylase N-4/N-6 domain protein; PFAM: Conserved hypothetical protein 95 YP_004370315.1 COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: nde:NIDE3444 serine-glyoxylate transaminase; PFAM: Aminotransferase, class V/cysteine desulfurase; PRIAM: Serine--glyoxylate transaminase; SPTR: Serine-glyoxylate transaminase; PFAM: Aminotransferase class-V YP_004370316.1 COGs: COG0111 phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006236:IPR006139:IPR006140:IPR002912; KEGG: sfu:Sfum_3649 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; Amino acid-binding ACT; PRIAM: phosphoglycerate dehydrogenase; SPTR: D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase YP_004370317.1 InterPro IPR014995; KEGG: dal:Dalk_3378 hypothetical protein; PFAM: protein of unknown function DUF1844; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1844) YP_004370318.1 COGs: COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; HAMAP: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; InterPro IPR004424:IPR006204:IPR013750; KEGG: dbr:Deba_0725 4-diphosphocytidyl-2C-methyl-D-erythritolkinase; PFAM: GHMP kinase; GHMP kinase, C-terminal; PRIAM: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; SPTR:4-diphosphocytidyl-2C-methyl-D-erythritolkinas e; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase YP_004370319.1 COGs: COG0462 phosphoribosylpyrophosphate synthetase; InterPro IPR005946:IPR000836; KEGG: sat:SYN_02767 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: ribose-phosphate diphosphokinase; SPTR: ribose-phosphate pyrophosphokinase; TIGRFAM: phosphoribosyl pyrophosphokinase; PFAM: phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase YP_004370320.1 COGs: COG0193 peptidyl-tRNA hydrolase; HAMAP: peptidyl-tRNA hydrolase; InterPro IPR001328; KEGG: dbr:Deba_0729 peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; PRIAM: Aminoacyl-tRNA hydrolase; SPTR: peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase YP_004370321.1 KEGG: mxa:MXAN_0742 hypothetical protein; SPTR: uncharacterized protein YP_004370322.1 COGs: COG3158 K+ transporter; HAMAP: Potassium uptake protein, low affinity, Kup; InterPro IPR023051:IPR003855; KEGG: dvm:DvMF_0985 K potassium transporter; PFAM: K+ potassium transporter; SPTR: Probable potassium transport system protein kup; PFAM: K+ potassium transporter; TIGRFAM: potassium uptake protein YP_004370323.1 COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: pca:Pcar_0086 TrkH family potassium uptake protein; PFAM: Cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: Potassium uptake protein, TrkH family; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family YP_004370324.1 COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037; KEGG: dba:Dbac_0339 TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; SPTR: TrkA-N domain protein; PFAM: TrkA-N domain; TrkA-C domain YP_004370325.1 KEGG: sfu:Sfum_1350 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2276) YP_004370326.1 KEGG: npu:Npun_F6101 hypothetical protein; SPTR: uncharacterized protein YP_004370327.1 KEGG: rmr:Rmar_0410 hypothetical protein; SPTR: uncharacterized protein YP_004370329.1 KEGG: dat:HRM2_29590 transposase (11 DDE domain protein); SPTR: transposase (11 DDE domain protein) YP_004370330.1 KEGG: gbm:Gbem_3907 hemolysin III family channel protein; SPTR: Magnetosome protein MamN YP_004370331.1 COGs: COG3344 Retron-type reverse transcriptase; InterPro IPR000477; KEGG: pph:Ppha_2459 CRISPR-associated protein Cas1; PFAM: Reverse transcriptase; SPTR: uncharacterized protein; PFAM: Reverse transcriptase (RNA-dependent DNA polymerase) YP_004370332.1 KEGG: nwa:Nwat_2561 hypothetical protein; SPTR: uncharacterized protein YP_004370333.1 InterPro IPR012753:IPR007712; KEGG: syp:SYNPCC7002_A2640 addiction module antitoxin; PFAM: Plasmid stabilisation system; SPTR: Addiction module toxin, RelE/StbE family subfamily; TIGRFAM: Addiction module toxin, RelE/StbE; PFAM: Plasmid stabilisation system protein; TIGRFAM: addiction module toxin, RelE/StbE family YP_004370334.1 COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002729; KEGG: cag:Cagg_3451 CRISPR-associated protein Cas1; PFAM: CRISPR-associated protein Cas1; SPTR: uncharacterized protein; TIGRFAM: CRISPR-associated protein Cas1; PFAM: CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated endonuclease Cas1 YP_004370335.1 COGs: COG1343 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR021127; KEGG: msv:Mesil_0709 CRISPR-associated protein Cas2; SPTR: uncharacterized protein; TIGRFAM: CRISPR associated protein Cas2; PFAM: CRISPR associated protein Cas2; TIGRFAM: CRISPR-associated endoribonuclease Cas2 YP_004370336.1 KEGG: sgl:SG1089 hypothetical protein; SPTR: uncharacterized protein YP_004370337.1 KEGG: xfn:XfasM23_1828 hypothetical protein; SPTR: Hypothetical phage protein; PFAM: protein of unknown function (DUF1640) YP_004370338.1 COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR004439:IPR001804; KEGG: dal:Dalk_1934 isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: Isocitrate dehydrogenase [NADP]; TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type YP_004370339.1 COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; HAMAP: bifunctional protein HldE; InterProIPR011913:IPR004821:IPR023030:IPR011611:IPR 004820; KEGG: dal:Dalk_2824 RfaE bifunctional protein; PFAM: Carbohydrate/purine kinase; Cytidylyltransferase; SPTR: bifunctional protein hldE; TIGRFAM: RfaE bifunctional protein, domain I; Cytidyltransferase-related; PFAM: Cytidylyltransferase; pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain II; rfaE bifunctional protein, domain I; cytidyltransferase-related domain YP_004370340.1 COGs: COG2114 adenylate cyclase 3 (some protein contain HAMP domain); InterPro IPR001054:IPR003251; KEGG: sat:SYN_01481 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; Rubrerythrin; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: adenylate cyclase; PFAM: adenylate and Guanylate cyclase catalytic domain; Rubrerythrin YP_004370341.1 InterPro IPR007202; KEGG: dol:Dole_1915 Fe-S cluster domain-containing protein; PFAM: Fe-S cluster; SPTR: Fe-S cluster; PFAM: Fe-S cluster YP_004370342.1 InterPro IPR011701; KEGG: sfu:Sfum_4017 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Genome sequencing data, contig C327; PFAM: Major Facilitator Superfamily YP_004370343.1 KEGG: cts:Ctha_1381 F0F1 ATP synthase subunit delta; SPTR: ATP synthase subunit delta YP_004370344.1 KEGG: zma:542747 eukaryotic initiation factor3; SPTR: Eukaryotic translation initiation factor 3 subunit A YP_004370345.1 COGs: COG1278 Cold shock protein; InterPro IPR011129:IPR002059; KEGG: glo:Glov_2627 cold-shock DNA-binding domain protein; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; SPTR: Cold-shock DNA-binding domain family protein; PFAM: 'Cold-shock' DNA-binding domain YP_004370346.1 KEGG: cin:100175752 similar to heterogeneous nuclear ribonucleoprotein U-like 1; SPTR: uncharacterized protein YP_004370347.1 COGs: COG0724 RNA-binding protein (RRM domain); InterPro IPR000504; KEGG: sfu:Sfum_0084 RNP-1 like RNA-binding protein; PFAM: RNA recognition motif domain; SMART: RNA recognition motif domain; SPTR: RNP-1 like RNA-binding protein; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YP_004370348.1 KEGG: tye:THEYE_A2091 hypothetical protein; SPTR: uncharacterized protein; PFAM: FecR protein YP_004370349.1 InterPro IPR019734:IPR013105:IPR001440; KEGG: tye:THEYE_A2092 tetratricopeptide repeat domain protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide domain protein YP_004370350.1 COGs: COG0046 phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; InterPro IPR000728:IPR010918; KEGG: sfu:Sfum_0432 phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; PRIAM: phosphoribosylformylglycinamidine synthase; SPTR: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycinamidine synthase II YP_004370351.1 InterPro IPR018449:IPR001450; KEGG: sfu:Sfum_0168 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: NIL domain; 4Fe-4S binding domain; SMART: NIL domain; SPTR: 4Fe-4S binding domain protein; PFAM: 4Fe-4S binding domain; NIL domain YP_004370352.1 InterPro IPR011701; KEGG: msv:Mesil_2519 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004370353.1 InterPro IPR001450; KEGG: dat:HRM2_40620 ferredoxin (4Fe-4S iron-sulfur cluster binding protein); PFAM: 4Fe-4S binding domain; SPTR: Ferredoxin (4Fe-4S iron-sulfur cluster binding protein) YP_004370354.1 KEGG: dat:HRM2_40610 hypothetical protein; SPTR: HD domain protein YP_004370355.1 COGs: COG1151 6Fe-6S prismane cluster-containing protein; HAMAP: Hybrid cluster protein; InterPro IPR010048:IPR004137; KEGG: sfu:Sfum_3446 hydroxylamine reductase; PFAM: Prismane; SPTR: Hydroxylamine reductase 2; TIGRFAM: Hybrid cluster protein; PFAM: Prismane/CO dehydrogenase; TIGRFAM: hydroxylamine reductase YP_004370356.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR001808; KEGG: dak:DaAHT2_1550 Crp/Fnr family transcriptional regulator; PFAM: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SMART: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SPTR: Cyclic nucleotide-binding:regulatory protein, Crp; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain YP_004370357.1 InterPro IPR011449; KEGG: dak:DaAHT2_1744 protein of unknown function DUF1555; PFAM: PEP-CTERM bacterial; SPTR: uncharacterized protein YP_004370358.1 InterPro IPR000644; KEGG: tye:THEYE_A0728 CBS domain pair, PFAM: cystathionine beta-synthase, core; SPTR: CBS-domain-containing protein; PFAM: CBS domain YP_004370359.1 COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR004680; KEGG: tye:THEYE_A0729 transmembrane transport protein-like protein; PFAM: Divalent ion symporter; SPTR: transmembrane transport protein-like protein; PFAM: Sodium:sulfate symporter transmembrane region; TIGRFAM: anion transporter YP_004370360.1 COGs: COG1055 Na+/H+ antiporter NhaD and related arsenite permease; InterPro IPR004680; KEGG: tye:THEYE_A0731 arsenical pump membrane protein; PFAM: Divalent ion symporter; SPTR: Arsenical pump membrane protein; PFAM: Citrate transporter YP_004370361.1 COGs: COG1055 Na+/H+ antiporter NhaD and related arsenite permease; InterPro IPR004680; KEGG: tye:THEYE_A0731 arsenical pump membrane protein; PFAM: Divalent ion symporter; SPTR: Arsenical pump membrane protein; PFAM: Citrate transporter YP_004370362.1 COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR003018:IPR003661:IPR003594:IPR006016; KEGG: hau:Haur_2273 osmosensitive K+ channel signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; UspA; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SPTR: Sensory histidine kinase in two-component regulatory system wtih KdpE, regulation of potassium translocation; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Universal stress protein family; His Kinase A (phosphoacceptor) domain YP_004370363.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: scl:sce1356 two component system transcriptional regulatory protein; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Response regulator in two-component regulatory system with KdpD, regulation of potassium translocation (OmpR family); PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004370364.1 InterPro IPR005632; KEGG: glo:Glov_0761 outer membrane chaperone Skp (OmpH); PFAM: Outer membrane chaperone Skp (OmpH); SMART: Outer membrane chaperone Skp (OmpH); SPTR: Outer membrane chaperone Skp (OmpH); PFAM: Outer membrane protein (OmpH-like) YP_004370365.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR017475:IPR003362; KEGG: dma:DMR_28260 glycosyltransferase; PFAM: Bacterial sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; TIGRFAM: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase YP_004370366.1 COGs: COG0489 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_1363 lipopolysaccharide biosynthesis; SPTR: Lipopolysaccharide biosynthesis YP_004370367.1 COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR003715; KEGG: ppd:Ppro_2881 polysaccharide export protein; PFAM: polysaccharide export protein; SPTR: polysaccharide export protein; PFAM: polysaccharide biosynthesis/export protein YP_004370368.1 KEGG: tps:THAPSDRAFT_24090 hypothetical protein; SPTR: uncharacterized protein YP_004370369.1 COGs: COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis; InterPro IPR003856; KEGG: ppd:Ppro_2880 lipopolysaccharide biosynthesis; PFAM: Lipopolysaccharide biosynthesis; SPTR: Lipopolysaccharide biosynthesis; PFAM: Chain length determinant protein YP_004370370.1 InterPro IPR007016; KEGG: sti:Sthe_1139 O-antigen polymerase; PFAM: O-antigen ligase-related; SPTR: Membrane protein of EXOQ family, involved in exopolysaccharide production; PFAM: O-Antigen ligase YP_004370371.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: mba:Mbar_A0234 lipopolysaccharide O-side chain biosynthesis protein (O-antigen transpoter); PFAM: polysaccharide biosynthesis protein; SPTR: Lipopolysaccharide O-side chain biosynthesis protein (O-antigen transpoter); PFAM: polysaccharide biosynthesis protein YP_004370372.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: acr:Acry_0205 glycosyl transferase, group 1; PFAM: glycosyl transferase, group 1; SPTR: glycosyl transferase, group 1; PFAM: glycosyl transferases group 1 YP_004370373.1 COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR006426:IPR000583:IPR001962; KEGG: nwa:Nwat_1772 exosortase 1 system-associated amidotransferase 1; PFAM: Asparagine synthase; glutamine amidotransferase, class-II; PRIAM: Asparagine synthase (glutamine-hydrolyzing); SPTR: Exosortase 1 system-associated amidotransferase 1; TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing) YP_004370374.1 InterPro IPR001173; KEGG: cyh:Cyan8802_2546 glycosyl transferase 2; PFAM: glycosyl transferase, family 2; SPTR: glycosyl transferase 2; PFAM: glycosyl transferase 2 YP_004370375.1 COGs: COG1922 Teichoic acid biosynthesis protein; InterPro IPR004629; KEGG: rxy:Rxyl_2691 WecB/TagA/CpsF family glycosyl transferase; PFAM: glycosyl transferase WecB/TagA/CpsF; SPTR: glycosyl transferase, WecB/TagA/CpsF family; TIGRFAM: glycosyl transferase WecB/TagA/CpsF; PFAM: glycosyl transferase WecB/TagA/CpsF family; TIGRFAM: bacterial polymer biosynthesis proteins, WecB/TagA/CpsF family YP_004370376.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: cts:Ctha_2017 glycosyl transferase group 1; PFAM: glycosyl transferase, group 1; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1 YP_004370377.1 InterPro IPR012480; KEGG: rop:ROP_58040 hypothetical protein; PFAM: Heparinase II/III-like; SPTR: uncharacterized protein; PFAM: Heparinase II/III-like protein YP_004370378.1 COGs: COG3534 Alpha-L-arabinofuranosidase; InterPro IPR010720; KEGG: chl:Chy400_1599 alpha-L-arabinofuranosidase-like protein; PFAM: Alpha-L-arabinofuranosidase, C-terminal; SMART: Alpha-L-arabinofuranosidase, C-terminal; SPTR: Alpha-L-arabinofuranosidase-like protein; PFAM: Alpha-L-arabinofuranosidase C-terminus YP_004370379.1 COGs: COG0474 Cation transport ATPase; InterProIPR004014:IPR001757:IPR002178:IPR008250:IPR 005834:IPR006068; KEGG: tra:Trad_1961 ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: ATPase, P-type, ATPase-associated domain; ATPase, P-type cation-transporter, N-terminal; phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; Haloacid dehalogenase-like hydrolase; ATPase, P-type cation-transporter, C-terminal; PRIAM: Calcium-transporting ATPase; SMART: ATPase, P-type cation-transporter, N-terminal; SPTR: ATPase, P-type (transporting), HAD superfamily, subfamily IC; TIGRFAM: ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; haloacid dehalogenase-like hydrolase; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Cation transporter/ATPase, N-terminus; TIGRFAM: plasma-membrane calcium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004370380.1 COGs: COG1483 ATPase (AAA+ superfamily); KEGG: bts:Btus_2857 ATPase AAA; SPTR: ATPase AAA; PFAM: protein of unknown function (DUF499) YP_004370381.1 KEGG: bts:Btus_2856 hypothetical protein; SPTR: uncharacterized protein YP_004370382.1 KEGG: mpl:Mpal_1787 hypothetical protein; SPTR: Molybdenum-pterin binding protein YP_004370383.1 COGs: COG1743 adenine-specific DNA methylase containing a Zn-ribbon; InterPro IPR009537; KEGG: bts:Btus_2855 protein of unknown function DUF1156; PFAM: Domain of unknown function DUF1156; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1156) YP_004370384.1 KEGG: zpr:ZPR_4172 exported hydrolase; SPTR: uncharacterized protein YP_004370385.1 KEGG: mar:MAE_16390 hypothetical protein; SPTR: uncharacterized protein YP_004370386.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR000330; KEGG: bts:Btus_2854 helicase domain protein; PFAM: Helicase, C-terminal; SNF2-related; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: Helicase domain protein; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain YP_004370387.1 COGs: COG1502 phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: dma:DMR_34600 nuclease; SMART: phospholipase D/transphosphatidylase; SPTR: phospholipase D/transphosphatidylase YP_004370388.1 COGs: COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G); InterPro IPR001041:IPR001450; KEGG: sat:SYN_00151 2Fe-2S iron-sulfur cluster binding domain-containing protein; PFAM: Ferredoxin; 4Fe-4S binding domain; SPTR: 2Fe-2S iron-sulfur cluster domain with dehydrogenase; PFAM: 2Fe-2S iron-sulfur cluster binding domain YP_004370389.1 COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR019575:IPR011538:IPR019554:IPR001450; KEGG: gbm:Gbem_1450 benzoyl-CoA reductase electron transfer protein; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S binding domain; PRIAM: NADH dehydrogenase (quinone); SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: Benzoyl-CoA reductase electron transfer protein, ; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain YP_004370390.1 COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: aar:Acear_2303 NAD(P)-dependent iron-only hydrogenase diaphorase component iron-sulfur protein; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: NAD(P)-dependent iron-only hydrogenase diaphorase component iron-sulfur protein; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit YP_004370391.1 COGs: COG1013 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: deg:DehalGT_0620 thiamine pyrophosphate protein domain protein TPP-binding protein; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: pyruvate synthase; SPTR: pyruvate oxidoreductase, beta chain; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain YP_004370392.1 COGs: COG0674 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: sat:SYN_00155 pyruvate:ferredoxin oxidoreductase alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; PRIAM: pyruvate synthase; SPTR: pyruvate:ferredoxin oxidoreductase alpha subunit; PFAM: domain YP_004370393.1 COGs: COG1144 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase delta subunit; InterPro IPR011898:IPR001450; KEGG: dly:Dehly_0628 pyruvate ferredoxin/flavodoxin oxidoreductase subunit delta; PFAM: 4Fe-4S binding domain; SPTR: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family YP_004370394.1 COGs: COG1014 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR011894:IPR019752; KEGG: dbr:Deba_3204 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate/ketoisovalerate oxidoreductase, catalytic domain; PRIAM: pyruvate synthase; SPTR: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family YP_004370395.1 KEGG: dvi:Dvir_GJ22165 GJ22165 gene product from transcript GJ22165-RA YP_004370396.1 COGs: COG1515 Deoxyinosine 3'endonuclease (endonuclease V); HAMAP: Endonuclease V; InterPro IPR007581; KEGG: sat:SYN_01952 endonuclease V; PFAM: Endonuclease V; PRIAM: Deoxyribonuclease V; SPTR: Endonuclease V; PFAM: Endonuclease V YP_004370397.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: dbr:Deba_1215 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004370398.1 COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; HAMAP: Lysidine-tRNA(Ile) synthetase; InterProIPR012796:IPR012795:IPR012094:IPR011063:IPR 015262; KEGG: sfu:Sfum_1265 tRNA(Ile)-lysidine synthetase; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase; Lysidine-tRNA(Ile) synthetase, substrate-binding domain; SMART: Lysidine-tRNA(Ile) synthetase, C-terminal; SPTR: tRNA(Ile)-lysidine synthase; TIGRFAM: Lysidine-tRNA(Ile) synthetase, N-terminal; Lysidine-tRNA(Ile) synthetase, C-terminal; PFAM: TilS substrate C-terminal domain; PP-loop family; TilS substrate binding domain; TIGRFAM: tRNA(Ile)-lysidine synthetase, C-terminal domain; tRNA(Ile)-lysidine synthetase, N-terminal domain YP_004370399.1 COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: fri:FraEuI1c_5133 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain YP_004370400.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: dly:Dehly_0266 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004370401.1 COGs: COG1615 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0182; InterPro IPR005372; KEGG: sfu:Sfum_2137 hypothetical protein; PFAM: Uncharacterised protein family UPF0182; SPTR: UPF0182 protein Sfum_2137; PFAM: Uncharacterised protein family (UPF0182) YP_004370402.1 InterPro IPR007060; KEGG: dal:Dalk_4413 septum formation initiator; PFAM: Septum formation initiator; SPTR: Septum formation initiator; PFAM: Septum formation initiator YP_004370403.1 COGs: COG0231 translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); HAMAP: translation elongation factor P; InterPro IPR015365:IPR011768:IPR013185:IPR001059; KEGG: dma:DMR_23980 elongation factor P; PFAM: Elongation factor P, C-terminal; translation elongation factor, KOW-like; translation elongation factor P/YeiP, central; SMART: Elongation factor P, C-terminal; SPTR: Elongation factor P; TIGRFAM: translation elongation factor P; PFAM: Elongation factor P, C-terminal; Elongation factor P (EF-P) KOW-like domain; Elongation factor P (EF-P) OB domain; TIGRFAM: translation elongation factor P YP_004370404.1 KEGG: dma:DMR_02240 hypothetical protein; SPTR: uncharacterized protein YP_004370405.1 COGs: COG0261 ribosomal protein L21; HAMAP: ribosomal protein L21; InterPro IPR001787; KEGG: sfu:Sfum_3639 50S ribosomal protein L21; PFAM: ribosomal protein L21; SPTR: 50S ribosomal protein L21; TIGRFAM: ribosomal protein L21; PFAM: ribosomal prokaryotic L21 protein; TIGRFAM: ribosomal protein L21 YP_004370406.1 COGs: COG0211 ribosomal protein L27; HAMAP: ribosomal protein L27; InterPro IPR001684; KEGG: dal:Dalk_4115 50S ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: ribosomal protein L27; PFAM: ribosomal L27 protein; TIGRFAM: ribosomal protein L27 YP_004370407.1 COGs: COG0536 GTPase; HAMAP: GTP-binding protein Obg/CgtA; InterPro IPR014100:IPR006169:IPR002917; KEGG: gsu:GSU3213 GTPase ObgE; PFAM: GTP1/OBG subdomain; GTP-binding protein, HSR1-related; SPTR: GTPase obg; TIGRFAM: GTP-binding protein Obg/CgtA; PFAM: GTPase of unknown function; GTP1/OBG; TIGRFAM: Obg family GTPase CgtA YP_004370408.1 COGs: COG0263 glutamate 5-kinase; HAMAP: glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase; InterPro IPR002478:IPR005715:IPR001048; KEGG: ppd:Ppro_2953 gamma-glutamyl kinase; PFAM: aspartate/glutamate/uridylate kinase; Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: glutamate 5-kinase; TIGRFAM: glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase; PFAM: Amino acid kinase; PUA domain; TIGRFAM: glutamate 5-kinase YP_004370409.1 COGs: COG0014 Gamma-glutamyl phosphate reductase; HAMAP: glutamate-5-semialdehyde dehydrogenase; InterPro IPR000965:IPR012134:IPR015590; KEGG: dbr:Deba_2403 gamma-glutamyl phosphate reductase; PFAM: Aldehyde dehydrogenase domain; PRIAM: glutamate-5-semialdehyde dehydrogenase; SPTR: Gamma-glutamyl phosphate reductase; TIGRFAM: Gamma-glutamyl phosphate reductase GPR; PFAM: Aldehyde dehydrogenase; TIGRFAM: gamma-glutamyl phosphate reductase YP_004370410.1 COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; HAMAP: Probable nicotinate-nucleotide adenylyltransferase; InterPro IPR004821:IPR005248:IPR004820; KEGG: sfu:Sfum_3645 nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: Cytidylyltransferase; PRIAM: Nicotinate-nucleotide adenylyltransferase; SPTR: Nicotinate-nucleotide adenylyltransferase; TIGRFAM: Probable nicotinate-nucleotide adenylyltransferase; Cytidyltransferase-related; PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain YP_004370411.1 COGs: COG4783 Zn-dependent protease contains TPR repeats; InterPro IPR019734:IPR001915:IPR001440; KEGG: sfu:Sfum_3647 peptidase M48, Ste24p; PFAM: peptidase M48; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: uncharacterized protein; PFAM: peptidase M48; Tetratricopeptide repeat YP_004370412.1 InterPro IPR013429; KEGG: sfu:Sfum_1903 FmdB family regulatory protein; PFAM: Regulatory protein, FmdB, SMART: Regulatory protein, FmdB, SPTR: regulatory protein, FmdB family; TIGRFAM: Regulatory protein, FmdB, PFAM: Zinc ribbon domain; TIGRFAM: regulatory protein, FmdB family YP_004370414.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: gur:Gura_0976 polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: polysaccharide deacetylase; PFAM: polysaccharide deacetylase YP_004370415.1 COGs: COG1306 conserved hypothetical protein; KEGG: afr:AFE_2171 GTP-binding protein; SPTR: GTP-binding protein YP_004370416.1 COGs: COG4089 membrane protein; InterPro IPR011672; KEGG: sfu:Sfum_0878 hypothetical protein; PFAM: protein of unknown function DUF1614; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1614) YP_004370417.1 COGs: COG3829 transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterPro IPR003593:IPR002078:IPR002197; KEGG: afw:Anae109_2442 two component, sigma54 specific, fis family transcriptional regulator; PFAM: RNA polymerase sigma factor 54, interaction; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004370418.1 KEGG: dal:Dalk_1452 hypothetical protein; SPTR: uncharacterized protein YP_004370419.1 InterPro IPR018711; KEGG: dbr:Deba_2799 protein of unknown function DUF2233, periplasmic; PFAM: phosphodiester alpha-GlcNAcase; SPTR: uncharacterized protein; PFAM: Predicted periplasmic protein (DUF2233) YP_004370420.1 COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: sfu:Sfum_3626 TatD family hydrolase; PFAM: Deoxyribonuclease, TatD-related; SPTR: TatD-related deoxyribonuclease; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family YP_004370421.1 InterPro IPR003356; KEGG: hla:Hlac_3519 N-6 DNA methylase; PFAM: DNA methylase, adenine-specific; SPTR: N-6 DNA methylase; PFAM: N-6 DNA methylase YP_004370422.1 COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR011078:IPR001608; KEGG: gsu:GSU2544 hypothetical protein; PFAM: Alanine racemase, N-terminal; SPTR: uncharacterized protein; TIGRFAM: pyridoxal phosphate-dependent enzyme, YBL036C type; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family YP_004370423.1 KEGG: scl:sce0621 hypothetical protein; SPTR: uncharacterized protein; PFAM: Thioredoxin YP_004370424.1 COGs: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit BcrC/BadD/HgdB; InterPro IPR010327; KEGG: adg:Adeg_0480 2-hydroxyglutaryl-CoA dehydratase D-component; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; SPTR: 2-hydroxyglutaryl-CoA dehydratase D-component; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component YP_004370425.1 COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR008275:IPR002731; KEGG: hmo:HM1_0462 activator of (R)-2-hydroxyglutaryl-coa dehydratase domain protein; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; SPTR: Activator of (R)-2-hydroxyglutaryl-coa dehydratase domain protein; TIGRFAM: CoA enzyme activase; PFAM: BadF/BadG/BcrA/BcrD ATPase; TIGRFAM: CoA-substrate-specific enzyme activase YP_004370426.1 InterPro IPR007842; KEGG: rmr:Rmar_2668 HEPN domain protein; PFAM: HEPN; SMART: HEPN; SPTR: HEPN domain protein; PFAM: HEPN domain YP_004370427.1 InterPro IPR002934; KEGG: azl:AZL_009230 DNA polymerase beta domain protein; PFAM: nucleotidyl transferase domain; SPTR: DNA polymerase, beta domain protein region; PFAM: nucleotidyltransferase domain YP_004370428.1 KEGG: bcl:ABC2856 transcriptional activator; SPTR: Conserved domain protein YP_004370429.1 COGs: COG1994 Zn-dependent protease; InterPro IPR008915; KEGG: saf:SULAZ_1069 membrane-associated zinc metalloprotease; PFAM: peptidase M50; SPTR: membrane-associated zinc metalloprotease; PFAM: peptidase M50 YP_004370430.1 COGs: COG1109 phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846:IPR005843; KEGG: gem:GM21_2649 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; SPTR: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; PFAM: phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase, C-terminal domain; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific YP_004370431.1 COGs: COG0499 S-adenosylhomocysteine hydrolase; HAMAP: adenosylhomocysteinase; InterPro IPR000043:IPR015878; KEGG: sfu:Sfum_0366 S-adenosyl-L-homocysteine hydrolase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding; adenosylhomocysteinase; PRIAM: adenosylhomocysteinase; SPTR: adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase YP_004370432.1 COGs: COG0192 S-adenosylmethionine synthetase; HAMAP: S-adenosylmethionine synthetase; InterPro IPR002133:IPR022628:IPR022629:IPR022630; KEGG: geo:Geob_2241 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal; PRIAM: methionine adenosyltransferase; SPTR: S-adenosylmethionine synthase 2; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase YP_004370434.1 COGs: COG0853 aspartate 1-decarboxylase; HAMAP: aspartate decarboxylase; InterPro IPR003190; KEGG: sfu:Sfum_0368 aspartate 1-decarboxylase; PFAM: aspartate decarboxylase; PRIAM: aspartate 1-decarboxylase; SPTR: aspartate 1-decarboxylase; TIGRFAM: aspartate decarboxylase; PFAM: aspartate decarboxylase; TIGRFAM: L-aspartate-alpha-decarboxylase YP_004370435.1 COGs: COG0414 Panthothenate synthetase; HAMAP: Pantoate-beta-alanine ligase; InterPro IPR003721; KEGG: sat:SYN_00420 pantoate--beta-alanine ligase; PFAM: Pantoate-beta-alanine ligase; SPTR: Pantothenate synthetase; TIGRFAM: Pantoate-beta-alanine ligase; PFAM: Pantoate-beta-alanine ligase; TIGRFAM: pantoate--beta-alanine ligase YP_004370436.1 InterPro IPR000644; KEGG: sfu:Sfum_2661 CBS domain-containing protein; PFAM: cystathionine beta-synthase, core; SMART: cystathionine beta-synthase, core; SPTR: hypothetical protein; PFAM: CBS domain YP_004370437.1 COGs: COG0517 FOG: CBS domain; InterPro IPR000644; KEGG: sfu:Sfum_2660 signal-transduction protein; PFAM: cystathionine beta-synthase, core; SPTR: signal-transduction protein with CBS domains; PFAM: CBS domain YP_004370438.1 COGs: COG2119 membrane protein; InterPro IPR001727; KEGG: mta:Moth_0395 hypothetical protein; PFAM: Uncharacterised protein family UPF0016; SPTR: uncharacterized protein; PFAM: Uncharacterized protein family UPF0016 YP_004370439.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: gur:Gura_2371 acriflavin resistance protein; PFAM: Acriflavin resistance protein; SPTR: Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family YP_004370440.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: gur:Gura_2372 RND family efflux transporter MFP subunit; PFAM: Secretion protein HlyD; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004370441.1 KEGG: bmr:BMI_I121 25 kDa outer-membrane immunogenic protein precursor; SPTR: Outer membrane protein YP_004370442.1 COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371:IPR000537; KEGG: dak:DaAHT2_0572 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase related; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase-related; PFAM: UbiA prenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase YP_004370443.1 COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830:IPR022390; KEGG: dma:DMR_21400 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Carboxylyase-related; SPTR: UbiD family decarboxylase; TIGRFAM: Menaquinone biosynthesis decarboxylase, SCO4490; Carboxylyase-related; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: menaquinone biosynthesis decarboxylase, SCO4490 family; UbiD family decarboxylases YP_004370444.1 COGs: COG1427 periplasmic solute-binding protein; InterPro IPR003773; KEGG: sfu:Sfum_3086 hypothetical protein; PFAM: protein of unknown function DUF178; SPTR: uncharacterized protein; PFAM: periplasminc binding protein (DUF178) YP_004370445.1 COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: sfu:Sfum_3087 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Amidohydrolase; PFAM: Amidohydrolase YP_004370446.1 COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR000845; KEGG: mfv:Mfer_0491 methylthioadenosine phosphorylase; PFAM: nucleoside phosphorylase domain; PRIAM: S-methyl-5'-thioadenosine phosphorylase; SPTR: Similar to 5'-methylthioadenosine phosphorylase; PFAM: phosphorylase superfamily YP_004370447.1 COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR022431:IPR020050:IPR007197; KEGG: dak:DaAHT2_0567 radical SAM protein; PFAM: Radical SAM; SPTR: radical SAM protein; TIGRFAM: Menaquinone biosynthesis, SCO4550; FO synthase, subunit 2; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family YP_004370448.1 COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR006638:IPR022432:IPR020050:IPR007197; KEGG: chy:CHY_1806 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: radical SAM protein; TIGRFAM: Menaquinone biosynthesis, SCO4494, predicted; FO synthase, subunit 2; PFAM: Radical SAM superfamily; TIGRFAM: menaquinone biosynthesis protein, SCO4494 family; radical SAM protein, CofH subfamily YP_004370449.1 COGs: COG1309 transcriptional regulator; InterPro IPR001647; KEGG: sfu:Sfum_3090 TetR family transcriptional regulator; PFAM: transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: TetR family transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004370450.1 InterPro IPR002559; KEGG: app:CAP2UW1_3182 transposase IS4 family protein; PFAM: transposase, IS4-like; SPTR: transposase IS4 family protein; PFAM: transposase DDE domain YP_004370451.1 KEGG: app:CAP2UW1_2688 hypothetical protein; SPTR: uncharacterized protein YP_004370452.1 COGs: COG0525 Valyl-tRNA synthetase; HAMAP: Valyl-tRNA synthetase; InterPro IPR002303:IPR002300:IPR013155:IPR019499; KEGG: dbr:Deba_2001 valyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ia; Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; Valyl-tRNA synthetase, class Ia, tRNA-binding arm; PRIAM: Valine--tRNA ligase; SPTR: Valyl-tRNA synthetase; TIGRFAM: Valyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Valyl tRNA synthetase tRNA binding arm; TIGRFAM: valyl-tRNA synthetase YP_004370453.1 COGs: COG0141 histidinol dehydrogenase; HAMAP: histidinol dehydrogenase, prokaryotic-type; InterPro IPR012131; KEGG: dbr:Deba_1224 histidinol dehydrogenase; PFAM: histidinol dehydrogenase, prokaryotic-type; PRIAM: histidinol dehydrogenase; SPTR: histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase, prokaryotic-type; PFAM: histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase YP_004370454.1 COGs: COG1469 conserved hypothetical protein; InterPro IPR003801; KEGG: dbr:Deba_2229 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase FolE2/MptA; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase folE2; TIGRFAM: GTP cyclohydrolase FolE2/MptA; PFAM: Uncharacterized ACR, COG1469; TIGRFAM: TIGR00294 family protein YP_004370455.1 InterPro IPR001077; KEGG: gme:Gmet_1733 O-methyltransferase; PFAM: O-methyltransferase, family 2; SPTR: O-methyltransferase, family 2; PFAM: O-methyltransferase YP_004370456.1 COGs: COG0398 conserved hypothetical protein; InterPro IPR015414; KEGG: dal:Dalk_0616 hypothetical protein; PFAM: hypothetical protein; SPTR: uncharacterized protein; PFAM: hypothetical protein YP_004370457.1 COGs: COG1242 Fe-S oxidoreductase; InterPro IPR006638:IPR005911:IPR007197; KEGG: dal:Dalk_2634 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP01212; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM protein, TIGR01212 family YP_004370458.1 COGs: COG1385 conserved hypothetical protein; InterPro IPR006700; KEGG: dat:HRM2_20880 hypothetical protein; PFAM: ribosomal RNA small subunit methyltransferase E; SPTR: uncharacterized protein; TIGRFAM: ribosomal RNA small subunit methyltransferase E; PFAM: RNA methyltransferase; TIGRFAM: RNA methyltransferase, RsmE family YP_004370459.1 COGs: COG2264 ribosomal protein L11 methylase; HAMAP: ribosomal protein L11 methyltransferase; InterPro IPR004498:IPR010456; KEGG: sat:SYN_02277 ribosomal protein L11 methyltransferase; PFAM: ribosomal L11 methyltransferase, PrmA; SPTR: ribosomal protein L11 methyltransferase; PFAM: ribosomal protein L11 methyltransferase (PrmA); TIGRFAM: ribosomal protein L11 methyltransferase YP_004370460.1 COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: hse:Hsero_1817 Zn-dependent hydrolase; SPTR: Zn-dependent hydrolases of the beta-lactamase fold protein YP_004370461.1 KEGG: sfu:Sfum_2160 hypothetical protein; SPTR: uncharacterized protein YP_004370462.1 COGs: COG0824 thioesterase; InterPro IPR006684:IPR006683; KEGG: aba:Acid345_1409 4-hydroxybenzoyl-CoA thioesterase; PFAM: Thioesterase superfamily; SPTR: 4-hydroxybenzoyl-CoA thioesterase; TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase; manually curated; PFAM: Thioesterase superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family YP_004370463.1 COGs: COG0203 ribosomal protein L17; HAMAP: ribosomal protein L17; InterPro IPR000456; KEGG: gme:Gmet_0654 50S ribosomal protein L17; PFAM: ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: ribosomal protein L17; PFAM: ribosomal protein L17; TIGRFAM: ribosomal protein L17 YP_004370464.1 COGs: COG0202 DNA-directed RNA polymerase alpha subunit/40 kD subunit; HAMAP: DNA-directed RNA polymerase, alpha subunit; InterProIPR011263:IPR011773:IPR011261:IPR011262:IPR 011260; KEGG: sfu:Sfum_1582 DNA-directed RNA polymerase subunit alpha; PFAM: DNA-directed RNA polymerase, insert domain; DNA-directed RNA polymerase, dimerisation; RNA polymerase, alpha subunit, C-terminal; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type; SPTR: DNA-directed RNA polymerase subunit alpha; TIGRFAM: DNA-directed RNA polymerase, alpha subunit; PFAM: RNA polymerase Rpb3/Rpb11 dimerisation domain; RNA polymerase Rpb3/RpoA insert domain; Bacterial RNA polymerase, alpha chain C terminal domain; TIGRFAM: DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type YP_004370465.1 COGs: COG0522 ribosomal protein S4 and related protein; InterPro IPR002942:IPR005709:IPR001912; KEGG: ppd:Ppro_0705 30S ribosomal protein S4; PFAM: ribosomal protein S4/S9, N-terminal; RNA-binding S4; SMART: RNA-binding S4; SPTR: 30S ribosomal protein S4; TIGRFAM: ribosomal protein S4, bacterial-type; PFAM: ribosomal protein S4/S9 N-terminal domain; S4 domain; TIGRFAM: ribosomal protein S4, bacterial/organelle type YP_004370466.1 COGs: COG0100 ribosomal protein S11; InterPro IPR019981:IPR001971; KEGG: gme:Gmet_0651 30S ribosomal protein S11; PFAM: ribosomal protein S11; SPTR: 30S ribosomal protein S11; TIGRFAM: ribosomal protein S11, bacterial-type; PFAM: ribosomal protein S11; TIGRFAM: 30S ribosomal protein S11 YP_004370467.1 COGs: COG0099 ribosomal protein S13; InterPro IPR019980:IPR001892; KEGG: sfu:Sfum_1579 30S ribosomal protein S13; PFAM: ribosomal protein S13; SPTR: 30S ribosomal protein S13; TIGRFAM: ribosomal protein S13, bacterial-type; PFAM: ribosomal protein S13/S18; TIGRFAM: 30S ribosomal protein S13 YP_004370468.1 HAMAP: ribosomal protein L36; InterPro IPR000473; KEGG: pca:Pcar_0724 ribosomal protein L36; PFAM: ribosomal protein L36; SPTR: 50S ribosomal protein L36; TIGRFAM: ribosomal protein L36; manually curated; PFAM: ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type YP_004370469.1 COGs: COG0361 translation initiation factor 1 (IF-1); HAMAP: translation initiation factor IF-1; InterPro IPR022967:IPR004368:IPR006196; KEGG: dps:DP1147 translation initiation factor IF-1; PFAM: RNA-binding domain, S1, IF1 type; SMART: RNA-binding domain, S1; SPTR: translation initiation factor IF-1; TIGRFAM: translation initiation factor IF-1; PFAM: translation initiation factor 1A / IF-1; TIGRFAM: translation initiation factor IF-1 YP_004370470.1 COGs: COG0024 methionine aminopeptidase; InterPro IPR002467:IPR000994; KEGG: hor:Hore_01380 methionine aminopeptidase, type I; PFAM: peptidase M24, structural domain; PRIAM: methionyl aminopeptidase; SPTR: methionine aminopeptidase; TIGRFAM: peptidase M24A, methionine aminopeptidase, subfamily 1; PFAM: Metallopeptidase M24; TIGRFAM: methionine aminopeptidase, type I YP_004370471.1 COGs: COG0563 adenylate kinase and related kinase; HAMAP: adenylate kinase; InterPro IPR006259:IPR000850:IPR007862; KEGG: dbr:Deba_2917 adenylate kinase; PFAM: adenylate kinase; adenylate kinase, active site lid domain; SPTR: adenylate kinase; TIGRFAM: adenylate kinase, subfamily; PFAM: adenylate kinase, active site lid; adenylate kinase; TIGRFAM: adenylate kinases YP_004370472.1 COGs: COG0201 Preprotein translocase subunit SecY; InterPro IPR002208; KEGG: dat:HRM2_36060 preprotein translocase subunit SecY; PFAM: SecY protein; SPTR: Preprotein translocase subunit secY; TIGRFAM: SecY protein; PFAM: eubacterial secY protein; TIGRFAM: preprotein translocase, SecY subunit YP_004370473.1 COGs: COG0200 ribosomal protein L15; InterPro IPR005749; KEGG: sfu:Sfum_1574 ribosomal protein L15; SPTR: 50S ribosomal protein L15; TIGRFAM: ribosomal protein L15, bacterial-type; PFAM: ribosomal protein L18e/L15; TIGRFAM: ribosomal protein L15, bacterial/organelle YP_004370474.1 InterPro IPR005996:IPR016082; KEGG: gwc:GWCH70_0129 50S ribosomal protein L30; PFAM: ribosomal protein L30, ferredoxin-like fold domain; SPTR: 50S ribosomal protein L30; TIGRFAM: ribosomal protein L30, bacterial-type; PFAM: ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle YP_004370475.1 COGs: COG0098 ribosomal protein S5; InterPro IPR005712:IPR013810:IPR005324; KEGG: sfu:Sfum_1572 ribosomal protein S5; PFAM: ribosomal protein S5, N-terminal; ribosomal protein S5, C-terminal; SPTR: 30S ribosomal protein S5; TIGRFAM: ribosomal protein S5, bacterial-type; PFAM: ribosomal protein S5, C-terminal domain; ribosomal protein S5, N-terminal domain; TIGRFAM: ribosomal protein S5, bacterial/organelle type YP_004370476.1 COGs: COG0256 ribosomal protein L18; InterPro IPR004389:IPR005484; KEGG: tle:Tlet_0595 ribosomal protein L18; PFAM: ribosomal protein L18/L5; SPTR: 50S ribosomal protein L18; TIGRFAM: ribosomal protein L18, bacterial; PFAM: ribosomal L18p/L5e family; TIGRFAM: ribosomal protein L18, bacterial type YP_004370477.1 COGs: COG0097 ribosomal protein L6P/L9E; InterPro IPR019906:IPR020040; KEGG: dal:Dalk_1900 50S ribosomal protein L6; PFAM: ribosomal protein L6, alpha-beta domain; SPTR: 50S ribosomal protein L6; TIGRFAM: ribosomal protein L6, bacterial-type; PFAM: ribosomal protein L6; TIGRFAM: ribosomal protein L6, bacterial type YP_004370478.1 COGs: COG0096 ribosomal protein S8; InterPro IPR000630; KEGG: hor:Hore_01310 ribosomal protein S8; PFAM: ribosomal protein S8; SPTR: 30S ribosomal protein S8; PFAM: ribosomal protein S8 YP_004370479.1 COGs: COG0199 ribosomal protein S14; InterPro IPR001209; KEGG: sfu:Sfum_1568 30S ribosomal protein S14; PFAM: ribosomal protein S14; SPTR: 30S ribosomal protein S14 type Z; manually curated; PFAM: ribosomal protein S14p/S29e YP_004370480.1 COGs: COG0094 ribosomal protein L5; InterPro IPR002132; KEGG: gme:Gmet_0638 50S ribosomal protein L5; PFAM: ribosomal protein L5; SPTR: 50S ribosomal protein L5; PFAM: ribosomal L5P family C-terminus; ribosomal protein L5 YP_004370481.1 COGs: COG0198 ribosomal protein L24; InterPro IPR005824:IPR003256; KEGG: dol:Dole_0719 50S ribosomal protein L24; PFAM: KOW; SMART: KOW; SPTR: 50S ribosomal protein L24; TIGRFAM: ribosomal protein L24; PFAM: KOW motif; TIGRFAM: ribosomal protein L24, bacterial/organelle YP_004370482.1 COGs: COG0093 ribosomal protein L14; InterPro IPR005745:IPR000218; KEGG: sfu:Sfum_1565 50S ribosomal protein L14; PFAM: ribosomal protein L14b/L23e; SPTR: 50S ribosomal protein L14; TIGRFAM: ribosomal protein L14, bacterial-type; PFAM: ribosomal protein L14p/L23e; TIGRFAM: ribosomal protein L14, bacterial/organelle YP_004370483.1 COGs: COG0186 ribosomal protein S17; InterPro IPR019984:IPR000266; KEGG: chd:Calhy_1012 30S ribosomal protein S17; PFAM: ribosomal protein S17; SPTR: 30S ribosomal protein S17; TIGRFAM: ribosomal protein S17, bacterial-type; PFAM: ribosomal protein S17; TIGRFAM: 30S ribosomal protein S17 YP_004370484.1 InterPro IPR001854; KEGG: pca:Pcar_0709 ribosomal protein L29; PFAM: ribosomal protein L29; SPTR: 50S ribosomal protein L29; TIGRFAM: ribosomal protein L29; PFAM: ribosomal L29 protein; TIGRFAM: ribosomal protein L29 YP_004370485.1 COGs: COG0197 ribosomal protein L16/L10E; HAMAP: ribosomal protein L16; InterPro IPR000114:IPR016180; KEGG: sfu:Sfum_1562 50S ribosomal protein L16; PFAM: ribosomal protein L10e/L16; SPTR: 50S ribosomal protein L16; TIGRFAM: ribosomal protein L16; PFAM: ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L16, bacterial/organelle YP_004370486.1 COGs: COG0092 ribosomal protein S3; InterProIPR004087:IPR005704:IPR008282:IPR004044:IPR 001351; KEGG: dbr:Deba_2932 ribosomal protein S3; PFAM: ribosomal protein S3, C-terminal; ribosomal protein S3, N-terminal; K Homology, type 2; SMART: K Homology; SPTR: ribosomal protein S3; TIGRFAM: ribosomal protein S3, bacterial; PFAM: KH domain; ribosomal protein S3, C-terminal domain; ribosomal protein S3, N-terminal domain; TIGRFAM: ribosomal protein S3, bacterial type YP_004370487.1 COGs: COG0091 ribosomal protein L22; InterPro IPR005727:IPR001063; KEGG: dbr:Deba_2933 ribosomal protein L22; PFAM: ribosomal protein L22/L17; SPTR: 50S ribosomal protein L22; TIGRFAM: ribosomal protein L22, bacterial-type; PFAM: ribosomal protein L22p/L17e; TIGRFAM: ribosomal protein L22, bacterial type YP_004370488.1 COGs: COG0185 ribosomal protein S19; InterPro IPR005732:IPR002222; KEGG: sfu:Sfum_1559 ribosomal protein S19; PFAM: ribosomal protein S19/S15; SPTR: 30S ribosomal protein S19; TIGRFAM: ribosomal protein S19, bacterial-type; PFAM: ribosomal protein S19; TIGRFAM: ribosomal protein S19, bacterial/organelle YP_004370489.1 COGs: COG0090 ribosomal protein L2; InterPro IPR005880:IPR022666:IPR022669; KEGG: dal:Dalk_1912 50S ribosomal protein L2; PFAM: ribosomal protein L2, C-terminal; ribosomal proteins L2, RNA binding domain; SPTR: 50S ribosomal protein L2; TIGRFAM: ribosomal protein L2, bacterial-type; PFAM: ribosomal proteins L2, RNA binding domain; ribosomal proteins L2, C-terminal domain; TIGRFAM: ribosomal protein L2, bacterial/organellar YP_004370490.1 COGs: COG0089 ribosomal protein L23; InterPro IPR013025; KEGG: dol:Dole_0710 50S ribosomal protein L23; PFAM: ribosomal protein L25/L23; SPTR: 50S ribosomal protein L23; PFAM: ribosomal protein L23 YP_004370491.1 COGs: COG0088 ribosomal protein L4; InterPro IPR002136; KEGG: dbr:Deba_2937 ribosomal protein L4/L1e; PFAM: ribosomal protein L4/L1e; SPTR: ribosomal protein L4/L1e; PFAM: ribosomal protein L4/L1 family; TIGRFAM: 50S ribosomal protein L4, bacterial/organelle YP_004370492.1 COGs: COG0087 ribosomal protein L3; InterPro IPR019927:IPR000597; KEGG: sat:SYN_00985 50S ribosomal protein L3P; PFAM: ribosomal protein L3; SPTR: 50S ribosomal protein L3; TIGRFAM: ribosomal protein L3, bacterial/organelle-type; manually curated; PFAM: ribosomal protein L3; TIGRFAM: 50S ribosomal protein L3, bacterial YP_004370493.1 COGs: COG0051 ribosomal protein S10; HAMAP: ribosomal protein S10 subgroup; InterPro IPR005731:IPR001848; KEGG: gme:Gmet_0625 30S ribosomal protein S10; PFAM: ribosomal protein S10; SPTR: 30S ribosomal protein S10; TIGRFAM: ribosomal protein S10 subgroup; PFAM: ribosomal protein S10p/S20e; TIGRFAM: ribosomal protein S10, bacterial/organelle YP_004370494.1 COGs: COG0050 GTPase - translation elongation factors; InterProIPR004541:IPR005225:IPR000795:IPR004161:IPR 004160; KEGG: sfu:Sfum_1553 elongation factor Tu; PFAM: protein synthesis factor, GTP-binding; translation elongation factor EFTu/EF1A, domain 2; translation elongation factor EFTu/EF1A, C-terminal; SPTR: Elongation factor Tu; TIGRFAM: translation elongation factor EFTu/EF1A, bacterial/organelle; Small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu C-terminal domain; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU YP_004370495.1 COGs: COG0480 translation elongation factors (GTPase); InterProIPR005517:IPR000640:IPR004540:IPR005225:IPR 000795:IPR004161; KEGG: gme:Gmet_0623 elongation factor G; PFAM: protein synthesis factor, GTP-binding; translation elongation factor EFTu/EF1A, domain 2; translation elongation factor EFG/EF2, domain IV; translation elongation factor EFG/EF2, C-terminal; SMART: translation elongation factor EFG/EF2, domain IV; translation elongation factor EFG/EF2, C-terminal; SPTR: Elongation factor G 1; TIGRFAM: translation elongation factor EFG/EF2; Small GTP-binding protein; manually curated; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain YP_004370496.1 COGs: COG0049 ribosomal protein S7; InterPro IPR005717:IPR000235; KEGG: afw:Anae109_1908 30S ribosomal protein S7; PFAM: ribosomal protein S7; SPTR: 30S ribosomal protein S7; TIGRFAM: ribosomal protein S7, bacterial-type; PFAM: ribosomal protein S7p/S5e; TIGRFAM: ribosomal protein S7, bacterial/organelle YP_004370497.1 COGs: COG0048 ribosomal protein S12; InterPro IPR005679:IPR006032; KEGG: sfu:Sfum_1551 30S ribosomal protein S12; PFAM: ribosomal protein S12/S23; SPTR: 30S ribosomal protein S12; TIGRFAM: ribosomal protein S12, bacteria; PFAM: ribosomal protein S12; TIGRFAM: ribosomal protein S12, bacterial/organelle YP_004370498.1 COGs: COG0086 DNA-directed RNA polymerase beta' subunit/160 kD subunit; HAMAP: DNA-directed RNA polymerase, subunit beta-prime; InterProIPR006592:IPR012754:IPR007080:IPR000722:IPR 007066:IPR007083:IPR007081; KEGG: sfu:Sfum_1550 DNA-directed RNA polymerase, beta' subunit; PFAM: RNA polymerase Rpb1, domain 1; RNA polymerase, alpha subunit; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 5; SMART: RNA polymerase, N-terminal; SPTR: DNA-directed RNA polymerase subunit beta'; TIGRFAM: DNA-directed RNA polymerase, subunit beta-prime; PFAM: RNA polymerase Rpb1, domain 2; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 5; TIGRFAM: DNA-directed RNA polymerase, beta' subunit, predominant form YP_004370499.1 COGs: COG0085 DNA-directed RNA polymerase beta subunit/140 kD subunit; HAMAP: DNA-directed RNA polymerase, beta subunit, bacterial-type; InterProIPR010243:IPR007644:IPR007642:IPR007645:IPR 019462:IPR007120:IPR007641; KEGG: sfu:Sfum_1549 DNA-directed RNA polymerase, beta subunit; PFAM: DNA-directed RNA polymerase, subunit 2, domain 6; RNA polymerase Rpb2, domain 3; RNA polymerase, beta subunit, protrusion; RNA polymerase Rpb2, domain 2; DNA-directed RNA polymerase, beta subunit, external 1 domain; RNA polymerase Rpb2, domain 7; SPTR: DNA-directed RNA polymerase subunit beta; TIGRFAM: DNA-directed RNA polymerase, beta subunit, bacterial-type; PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 6; RNA polymerase beta subunit external 1 domain; RNA polymerase Rpb2, domain 2; RNA polymerase beta subunit; RNA polymerase Rpb2, domain 7; TIGRFAM: DNA-directed RNA polymerase, beta subunit YP_004370500.1 COGs: COG0222 ribosomal protein L7/L12; HAMAP: ribosomal protein L7/L12; InterPro IPR000206:IPR013823; KEGG: dak:DaAHT2_1460 ribosomal protein L7/L12; PFAM: ribosomal protein L7/L12, C-terminal; SPTR: 50S ribosomal protein L7/L12; TIGRFAM: ribosomal protein L7/L12; PFAM: ribosomal protein L7/L12 C-terminal domain; TIGRFAM: ribosomal protein L7/L12 YP_004370501.1 COGs: COG0244 ribosomal protein L10; HAMAP: ribosomal protein L10; InterPro IPR022973:IPR001790; KEGG: gur:Gura_1059 50S ribosomal protein L10; PFAM: ribosomal protein L10/acidic P0; SPTR: 50S ribosomal protein L10; PFAM: ribosomal protein L10 YP_004370502.1 COGs: COG0081 ribosomal protein L1; InterPro IPR005878:IPR002143; KEGG: sfu:Sfum_1546 ribosomal protein L1; PFAM: ribosomal protein L1; SPTR: 50S ribosomal protein L1; TIGRFAM: ribosomal protein L1, bacterial-type; PFAM: ribosomal protein L1p/L10e family; TIGRFAM: ribosomal protein L1, bacterial/chloroplast YP_004370503.1 COGs: COG0080 ribosomal protein L11; InterPro IPR000911:IPR006519:IPR020784:IPR020783; KEGG: sfu:Sfum_1545 ribosomal protein L11; PFAM: ribosomal protein L11, N-terminal domain; ribosomal protein L11, C-terminal domain; SMART: ribosomal protein L11; SPTR: 50S ribosomal protein L11; TIGRFAM: ribosomal protein L11, bacterial-type; PFAM: ribosomal protein L11, RNA binding domain; ribosomal protein L11, N-terminal domain; TIGRFAM: 50S ribosomal protein L11 YP_004370504.1 COGs: COG0250 transcription antiterminator; InterPro IPR006645:IPR005824:IPR001062; KEGG: sfu:Sfum_1544 NusG antitermination factor; PFAM: transcription antitermination protein, NusG, N-terminal; KOW; SMART: transcription antitermination protein, NusG, N-terminal; KOW; SPTR: transcription antitermination protein nusG; TIGRFAM: transcription antitermination protein, NusG; PFAM: transcription termination factor nusG; KOW motif; TIGRFAM: transcription termination/antitermination factor NusG YP_004370505.1 InterPro IPR005807:IPR001901; KEGG: dal:Dalk_1927 preprotein translocase, SecE subunit; PFAM: protein SecE/Sec61-gamma protein; SPTR: Preprotein translocase, SecE subunit; TIGRFAM: SecE subunit of protein translocation complex; PFAM: SecE/Sec61-gamma subunits of protein translocation complex; TIGRFAM: preprotein translocase, SecE subunit, bacterial YP_004370506.1 HAMAP: ribosomal protein L33; InterPro IPR001705; KEGG: aac:Aaci_2727 ribosomal protein L33; PFAM: ribosomal protein L33; SPTR: 50S ribosomal protein L33; TIGRFAM: ribosomal protein L33; manually curated; PFAM: ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type YP_004370507.1 COGs: COG0050 GTPase - translation elongation factors; InterProIPR004541:IPR005225:IPR000795:IPR004161:IPR 004160; KEGG: sfu:Sfum_1553 elongation factor Tu; PFAM: protein synthesis factor, GTP-binding; translation elongation factor EFTu/EF1A, domain 2; translation elongation factor EFTu/EF1A, C-terminal; SPTR: Elongation factor Tu; TIGRFAM: translation elongation factor EFTu/EF1A, bacterial/organelle; Small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu C-terminal domain; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU YP_004370508.1 InterPro IPR000551; KEGG: dak:DaAHT2_1238 transcriptional regulator, MerR family; PFAM: HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: transcriptional regulator, MerR family; PFAM: MerR family regulatory protein YP_004370509.1 COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017; KEGG: dba:Dbac_1216 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: cysteine-rich domain; SPTR: uncharacterized protein; PFAM: cysteine-rich domain YP_004370510.1 COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: ddf:DEFDS_1032 hypothetical protein; PFAM: YbbR-like; SPTR: YbbR-like; PFAM: YbbR-like protein YP_004370511.1 COGs: COG1624 conserved hypothetical protein; InterPro IPR014046:IPR003390; KEGG: dak:DaAHT2_0445 protein of unknown function DUF147; PFAM: DNA integrity scanning protein, DisA, N-terminal; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00159; PFAM: DisA bacterial checkpoint controller nucleotide-binding; TIGRFAM: TIGR00159 family protein YP_004370512.1 COGs: COG0294 dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: dak:DaAHT2_0903 dihydropteroate synthase; PFAM: Pterin-binding; PRIAM: dihydropteroate synthase; SPTR: dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase YP_004370513.1 COGs: COG0465 ATP-dependent Zn protease; InterProIPR003593:IPR005936:IPR011546:IPR003959:IPR 000642; KEGG: dbr:Deba_0762 ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; ATPase, AAA-type, core; peptidase M41, FtsH extracellular; PRIAM: Microtubule-severing ATPase; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent metalloprotease FtsH; TIGRFAM: peptidase M41, FtsH; PFAM: FtsH Extracellular; peptidase M41; ATPase associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH YP_004370514.1 COGs: COG0167 dihydroorotate dehydrogenase; InterPro IPR006062; KEGG: oih:OB1493 dihydroorotase dehydrogenase; PFAM: histidine biosynthesis; SPTR: dihydroorotate dehydrogenase; PFAM: dihydroorotate dehydrogenase YP_004370515.1 InterPro IPR010093; KEGG: mcu:HMPREF0573_10551 DNA-binding protein; SPTR: DNA-binding protein; TIGRFAM: Excisionase/Xis, DNA-binding; TIGRFAM: DNA binding domain, excisionase YP_004370516.1 KEGG: pab:PAB2076 resolvase related protein; SPTR: Resolvase related protein; TIGRFAM: DNA binding domain, excisionase YP_004370517.1 KEGG: nde:NIDE0636 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: DNA binding domain, excisionase YP_004370518.1 InterPro IPR006517; KEGG: dbr:Deba_3280 phage uncharacterized protein; SPTR: Phage uncharacterized protein; TIGRFAM: methanobacterium phage psiM2, terminase large subunit; TIGRFAM: phage uncharacterized protein ( large terminase), C-terminal domain YP_004370519.1 InterPro IPR009317; KEGG: cyn:Cyan7425_0020 ChaB family protein; PFAM: ChaB; SPTR: uncharacterized protein; PFAM: ChaB YP_004370520.1 COGs: COG4383 Mu-like prophage protein gp29; InterPro IPR009279; KEGG: sfu:Sfum_1877 hypothetical protein; PFAM: protein of unknown function DUF935; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF935) YP_004370521.1 COGs: COG4388 Mu-like prophage I protein; InterPro IPR019295; KEGG: sat:SYN_02300 Mu-like prophage FluMu I protein; PFAM: Mu-like prophage I protein; SPTR: Mu-like prophage Flumu I protein; PFAM: Mu-like prophage I protein YP_004370522.1 KEGG: sat:SYN_03379 cytoplasmic protein; SPTR: Hypothetical cytosolic protein YP_004370523.1 COGs: COG4397 Mu-like prophage major head subunit gpT; InterPro IPR018774; KEGG: sat:SYN_02298 Mu-like prophage major head subunit; PFAM: Mu-like major head subunit gpT, prophage; SPTR: Mu-like prophage major head subunit; PFAM: Mu-like prophage major head subunit gpT YP_004370524.1 KEGG: cre:CHLREDRAFT_194576 metalloproteinase of VMP family; SPTR: Metalloproteinase of VMP family YP_004370525.1 KEGG: sti:Sthe_2754 hypothetical protein; SPTR: Secreted protein YP_004370526.1 COGs: COG4387 Mu-like prophage protein gp36; InterPro IPR009752; KEGG: sat:SYN_02296 Mu-like prophage FluMu protein GP36; PFAM: protein of unknown function DUF1320; SPTR: Mu-like prophage Flumu protein gp36; PFAM: protein of unknown function (DUF1320) YP_004370527.1 KEGG: sfu:Sfum_1885 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1834) YP_004370528.1 KEGG: dbr:Deba_2733 hypothetical protein; SPTR: uncharacterized protein YP_004370529.1 KEGG: cbr:CBG12735 C. briggsae CBR-SMG-1 protein; SPTR: uncharacterized protein YP_004370530.1 InterPro IPR000556; KEGG: mag:amb3422 hypothetical protein; PFAM: glycoside hydrolase, 48F; SPTR: Baseplate wedge initiator YP_004370531.1 KEGG: ddi:DDB_G0291688 hypothetical protein; SPTR: uncharacterized protein YP_004370532.1 KEGG: svi:Svir_15460 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase YP_004370533.1 KEGG: sga:GALLO_1561 sensor histidine kinase (two component system); SPTR: sensor histidine kinase (Two component system) YP_004370534.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: ank:AnaeK_2607 cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-binding domain (CNMP-BD) protein; PFAM: Cyclic nucleotide-binding domain YP_004370535.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR001789:IPR003018:IPR003594:IPR003661; KEGG: hau:Haur_4259 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: Signal transduction response regulator, receiver domain; GAF; ATPase-like, ATP-binding domain; SPTR: Multi-sensor hybrid histidine kinase; PFAM: GAF domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain YP_004370536.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: plm:Plim_1915 sigma-54 factor interaction domain-containing protein; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: Acetoacetate metabolism regulatory protein ATOC; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004370537.1 COGs: COG0161 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; InterPro IPR005815:IPR005814; KEGG: dau:Daud_1328 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: adenosylmethionine--8-amino-7-oxononanoate transaminase; SPTR: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; TIGRFAM: adenosylmethionine--8-amino-7-oxononanoate aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate transaminase YP_004370538.1 COGs: COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; HAMAP: 3-deoxy-D-manno-octulosonate cytidylyltransferase; InterPro IPR004528:IPR003329; KEGG: dak:DaAHT2_0943 3-deoxy-D-manno-octulosonate cytidylyltransferase; PFAM: acylneuraminate cytidylyltransferase; PRIAM: 3-deoxy-manno-octulosonate cytidylyltransferase; SPTR: 3-deoxy-manno-octulosonate cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase; PFAM: Cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase YP_004370539.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR017730:IPR004176:IPR003959:IPR 013093:IPR019489; KEGG: dak:DaAHT2_0063 ATP-dependent chaperone ClpB; PFAM: ATPase, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent chaperone ClpB; TIGRFAM: Chaperonin ClpB; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB YP_004370540.1 COGs: COG0767 ABC-type transport system involved in resistance to organic solvents permease component; InterPro IPR003453; KEGG: gme:Gmet_0788 hypothetical protein; PFAM: Domain of unknown function DUF140; SPTR: uncharacterized protein; TIGRFAM: Domain of unknown function DUF140; PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein YP_004370541.1 COGs: COG1127 ABC-type transport system involved in resistance to organic solvents ATPase component; InterPro IPR003593:IPR003439; KEGG: gme:Gmet_0787 ABC transporter-related protein; PFAM: ABC transporter-like; PRIAM: iron ABC transporter ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter (ATP-binding protein); PFAM: ABC transporter YP_004370542.1 COGs: COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: gsu:GSU0815 mce-related protein; PFAM: Mammalian cell entry-related; SPTR: Mce-related protein; PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_004370543.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: gsu:GSU0814 outer membrane efflux protein; PFAM: Outer membrane efflux protein; SPTR: Outer membrane efflux protein, ; PFAM: Outer membrane efflux protein YP_004370544.1 COGs: COG2854 ABC-type transport system involved in resistance to organic solvents auxiliary component; InterPro IPR008869; KEGG: nde:NIDE0866 ABC transporter auxiliary component, ATP-dependent toluene efflux transporter; PFAM: Toluene tolerance Ttg2; SPTR: uncharacterized protein; PFAM: Toluene tolerance, Ttg2 YP_004370545.1 COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR003736:IPR006683; KEGG: sfu:Sfum_0232 hypothetical protein; PFAM: Thioesterase superfamily; SPTR: phenylacetic acid degradation protein PaaD; TIGRFAM: Phenylacetic acid degradation-related protein; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1; phenylacetic acid degradation protein PaaD YP_004370546.1 COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: sfu:Sfum_0376 lipid A biosynthesis acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase; SPTR: Lipid A biosynthesis acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase YP_004370547.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: hch:HCH_01055 glycosyltransferase; PFAM: glycosyl transferase, group 1; SPTR: glycosyltransferase; PFAM: glycosyl transferases group 1 YP_004370548.1 COGs: COG3063 Tfp pilus assembly protein PilF; InterPro IPR019734:IPR013105:IPR001440; KEGG: cyp:PCC8801_1300 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; SMART: Tetratricopeptide repeat; SPTR: TPR repeat-containing protein; PFAM: Tetratricopeptide repeat YP_004370549.1 COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; InterPro IPR001279; KEGG: sat:SYN_00175 metal-dependent hydrolase; PFAM: Beta-lactamase-like; SPTR: Metallo-beta-lactamase domain protein YP_004370550.1 COGs: COG1208 nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835; KEGG: dol:Dole_1992 aminoglycoside phosphotransferase; PFAM: nucleotidyl transferase; SPTR: nucleotidyl transferase; PFAM: nucleotidyl transferase YP_004370551.1 COGs: COG1839 conserved hypothetical protein; InterPro IPR007153; KEGG: cyh:Cyan8802_2301 protein of unknown function DUF355; PFAM: adenosine specific kinase; SPTR: uncharacterized protein; PFAM: adenosine specific kinase YP_004370552.1 COGs: COG0598 Mg2+ and Co2+ transporter; InterPro IPR004488:IPR002523; KEGG: gvi:gll1023 cation transporter; PFAM: Mg2+ transporter protein, CorA-like; SPTR: Gll1023 protein; TIGRFAM: Magnesium/cobalt transport protein CorA; PFAM: CorA-like Mg2+ transporter protein; TIGRFAM: magnesium Mg(2+) and cobalt Co(2+) transport protein (corA) YP_004370553.1 COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: sfu:Sfum_0862 extracellular ligand-binding receptor; PFAM: Extracellular ligand-binding receptor; SPTR: Extracellular ligand-binding receptor; PFAM: Receptor family ligand binding region YP_004370555.1 COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205:IPR005743:IPR006691; KEGG: gur:Gura_0005 DNA gyrase, A subunit; PFAM: DNA topoisomerase, type IIA, subunit A/C-terminal; DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase, type IIA, subunit A/C-terminal; SPTR: DNA gyrase subunit A; TIGRFAM: DNA gyrase, subunit A; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal domain, beta-propeller; TIGRFAM: DNA gyrase, A subunit YP_004370556.1 COGs: COG0240 glycerol-3-phosphate dehydrogenase; HAMAP: glycerol-3-phosphate dehydrogenase, NAD-dependent; InterPro IPR006168:IPR011128:IPR006109; KEGG: gbm:Gbem_0008 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; PFAM: glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal; glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal; SPTR: glycerol-3-phosphate dehydrogenase [NAD(P)+]; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus YP_004370557.1 InterPro IPR005358; KEGG: dba:Dbac_1736 protein of unknown function UPF0153; PFAM: Uncharacterised protein family UPF0153; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0153) YP_004370558.1 COGs: COG0143 methionyl-tRNA synthetase; HAMAP: methionyl-tRNA synthetase, class Ia; InterPro IPR014758:IPR004495:IPR015413:IPR002547; KEGG: sat:SYN_00558 methionyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class I (M); tRNA-binding domain; PRIAM: methionine--tRNA ligase; SPTR: methionyl-tRNA synthetase / protein secretion chaperonin; TIGRFAM: methionyl-tRNA synthetase, class Ia; methionyl-tRNA synthetase, class Ia, beta subunit, C-terminal; PFAM: tRNA synthetases class I (M); tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; methionyl-tRNA synthetase YP_004370559.1 COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR000064; KEGG: rmr:Rmar_1118 NLP/P60 protein; PFAM: NLP/P60; SPTR: NLP/P60 protein; PFAM: NlpC/P60 family YP_004370560.1 InterPro IPR002934; KEGG: mar:MAE_14620 DNA polymerase beta subunit; PFAM: nucleotidyl transferase domain; SPTR: DNA polymerase beta domain; PFAM: nucleotidyltransferase domain YP_004370561.1 KEGG: rrs:RoseRS_3516 hypothetical protein; SPTR: uncharacterized protein YP_004370562.1 COGs: COG1538 Outer membrane protein; InterPro IPR010131:IPR003423; KEGG: sfu:Sfum_3678 outer membrane efflux protein; PFAM: Outer membrane efflux protein; SPTR: Outer membrane efflux protein; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT; PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family YP_004370563.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR004764:IPR001036; KEGG: sfu:Sfum_3679 acriflavin resistance protein; PFAM: Acriflavin resistance protein; SPTR: Acriflavin resistance protein; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family YP_004370564.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: sfu:Sfum_3680 secretion protein HlyD family protein; PFAM: Secretion protein HlyD; SPTR: Secretion protein HlyD family protein; TIGRFAM: Secretion protein HlyD; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004370565.1 COGs: COG1309 transcriptional regulator; InterPro IPR001647; KEGG: dde:Dde_0960 TetR family transcriptional regulator; PFAM: transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: TetR family transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004370566.1 COGs: COG0584 glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: rci:RCIX2417 glycerophosphodiester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: glycerophosphodiester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase YP_004370567.1 COGs: COG1048 Aconitase A; InterPro IPR006250:IPR001030:IPR000573; KEGG: dak:DaAHT2_1713 aconitate hydratase; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel; SPTR: aconitate hydratase; TIGRFAM: Aconitase, PFAM: Aconitase C-terminal domain; Aconitase (aconitate hydratase); TIGRFAM: aconitate hydratase, , Aquifex type YP_004370568.1 InterPro IPR000086; KEGG: gme:Gmet_0068 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase; PFAM: NUDIX domain YP_004370569.1 COGs: COG1633 conserved hypothetical protein; InterPro IPR003251; KEGG: sat:SYN_00467 cytoplasmic protein; PFAM: Rubrerythrin; SPTR: Rubrerythrin; PFAM: Rubrerythrin YP_004370570.1 COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; InterPro IPR001279; KEGG: dal:Dalk_3435 beta-lactamase domain protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily YP_004370571.1 KEGG: gym:GYMC10_5974 hypothetical protein; SPTR: uncharacterized protein YP_004370572.1 COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: sfu:Sfum_1586 trans-hexaprenyltranstransferase; PFAM: polyprenyl synthetase; PRIAM: trans-hexaprenyltranstransferase; SPTR: trans-hexaprenyltranstransferase; PFAM: polyprenyl synthetase YP_004370573.1 COGs: COG0621 2-methylthioadenine synthetase; HAMAP: ribosomal protein S12 methylthiotransferase RimO; InterProIPR006638:IPR005839:IPR005840:IPR013848:IPR 007197; KEGG: ppd:Ppro_3094 MiaB-like tRNA modifying enzyme YliG; PFAM: methylthiotransferase, N-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: ribosomal protein S12 methylthiotransferase rimO; TIGRFAM: ribosomal protein S12 methylthiotransferase RimO; methylthiotransferase; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: ribosomal protein S12 methylthiotransferase RimO; radical SAM methylthiotransferase, MiaB/RimO family YP_004370574.1 KEGG: sfu:Sfum_1584 hypothetical protein; SPTR: uncharacterized protein YP_004370575.1 InterPro IPR002482:IPR008258:IPR018392; KEGG: gsu:GSU1010 Slt family transglycosylase; PFAM: Lytic transglycosylase-like, catalytic; peptidoglycan-binding lysin domain; SMART: peptidoglycan-binding Lysin subgroup; SPTR: transglycosylase, Slt family; PFAM: transglycosylase SLT domain; LysM domain YP_004370576.1 COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: tro:trd_A0511 hydrolase, carbon-nitrogen family protein; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Hydrolase, carbon-nitrogen family protein; PFAM: Carbon-nitrogen hydrolase YP_004370577.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; KEGG: tne:Tneu_1087 ABC transporter related; SPTR: ABC transporter related YP_004370578.1 COGs: COG0323 DNA mismatch repair enzyme (predicted ATPase); HAMAP: DNA mismatch repair protein, MutL; InterProIPR014790:IPR014763:IPR020667:IPR003594:IPR 013507; KEGG: gsu:GSU2001 DNA mismatch repair protein; PFAM: MutL, C-terminal, dimerisation; DNA mismatch repair protein, C-terminal; ATPase-like, ATP-binding domain; SMART: MutL, C-terminal, dimerisation; SPTR: DNA mismatch repair protein mutL; TIGRFAM: DNA mismatch repair protein, N-terminal; PFAM: MutL C terminal dimerisation domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA mismatch repair protein, C-terminal domain; TIGRFAM: DNA mismatch repair protein MutL YP_004370579.1 KEGG: dak:DaAHT2_1932 hypothetical protein; SPTR: uncharacterized protein YP_004370580.1 COGs: COG0689 RNase PH; HAMAP: ribonuclease phosphorolytic, bacterial-type; InterPro IPR002381:IPR001247:IPR015847; KEGG: gka:GK2666 ribonuclease PH; PFAM: Exoribonuclease, phosphorolytic domain 1; Exoribonuclease, phosphorolytic domain 2; PRIAM: tRNA nucleotidyltransferase; SPTR: ribonuclease PH; TIGRFAM: ribonuclease phosphorolytic, bacterial-type; PFAM: 3' exoribonuclease, domain 1; 3' exoribonuclease, domain 2; TIGRFAM: ribonuclease PH YP_004370581.1 COGs: COG0127 Xanthosine triphosphate pyrophosphatase; HAMAP: nucleoside-triphosphatase; InterPro IPR020922:IPR002637; KEGG: chy:CHY_0315 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; PFAM: Ham1-like protein; PRIAM: nucleoside-triphosphatase; SPTR: nucleoside-triphosphatase; TIGRFAM: Ham1-like protein; PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family YP_004370582.1 KEGG: fma:FMG_0788 integral membrane protein YP_004370583.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: bbe:BBR47_15160 transcriptional regulator; PFAM: HTH transcriptional regulator, AraC; SMART: Helix-turn-helix, AraC type, DNA binding domain; SPTR: transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004370584.1 COGs: COG0716 Flavodoxins; InterPro IPR008254:IPR001450; KEGG: dal:Dalk_2598 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; Flavodoxin/nitric oxide synthase; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_004370585.1 InterPro IPR002934:IPR001845; KEGG: dly:Dehly_1246 DNA polymerase beta domain-containing protein region; PFAM: nucleotidyl transferase domain; SMART: HTH transcriptional regulator, ArsR; SPTR: toxin-antitoxin system, toxin component YP_004370586.1 KEGG: dly:Dehly_1247 hypothetical protein; SPTR: uncharacterized protein YP_004370587.1 KEGG: ang:An02g11940 hypothetical protein; SPTR: Similarity to aminopeptidase METPRO02 from patent EP939131-A2 - Homo sapiens YP_004370588.1 KEGG: chd:Calhy_0413 hypothetical protein; SPTR: uncharacterized protein YP_004370589.1 COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982; KEGG: gsu:GSU0609 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: methylglyoxal synthase-like domain; AICARFT/IMPCHase bienzyme, transformylase domain; PRIAM: phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: methylglyoxal synthase-like domain; SPTR: bifunctional purine biosynthesis protein purH; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain YP_004370590.1 KEGG: ptm:GSPATT00026053001 hypothetical protein; SPTR: Chromosome undetermined scaffold_91, whole genome shotgun sequence YP_004370591.1 COGs: COG0151 phosphoribosylamine-glycine ligase; InterPro IPR020561; KEGG: syg:sync_2218 phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; PRIAM: phosphoribosylamine--glycine ligase; SPTR: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase, ATP-grasp (A) domain YP_004370592.1 KEGG: osa:4334132 Os03g0751600; SPTR: Heavy metal-associated domain containing protein, expressed YP_004370593.1 KEGG: geo:Geob_1696 TPR repeat-containing protein; SPTR: TPR repeat-containing protein YP_004370594.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR006638:IPR017834; KEGG: glo:Glov_3090 hopanoid biosynthesis associated radical SAM protein HpnJ; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; TIGRFAM: Hopanoid biosynthesis associated radical SAM protein HpnJ; PFAM: Radical SAM superfamily; B12 binding domain; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnJ YP_004370595.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: ter:Tery_4990 radical SAM family protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM; PFAM: Radical SAM superfamily YP_004370596.1 COGs: COG3394 conserved hypothetical protein; InterPro IPR006879:IPR017836; KEGG: geo:Geob_2290 hopanoid biosynthesis associated protein HpnK; PFAM: Uncharacterised protein family UPF0249/HpnK; SPTR: Hopanoid biosynthesis associated protein HpnK; TIGRFAM: Hopanoid biosynthesis associated protein HpnK; PFAM: YdjC-like protein; TIGRFAM: hopanoid biosynthesis associated protein HpnK YP_004370597.1 InterPro IPR000620; KEGG: gme:Gmet_2414 hypothetical protein; PFAM: Drug/metabolite transporter; SPTR: uncharacterized protein; PFAM: EamA-like transporter family YP_004370598.1 COGs: COG0415 Deoxyribodipyrimidine photolyase; InterPro IPR006050:IPR005101:IPR008148; KEGG: ppd:Ppro_2012 deoxyribodipyrimidine photolyase; PFAM: DNA photolyase, FAD-binding/Cryptochrome, C-terminal; DNA photolyase, N-terminal; SPTR: Deoxyribodipyrimidine photo-lyase type II; TIGRFAM: DNA photolyase, class 2; PFAM: FAD binding domain of DNA photolyase; DNA photolyase; TIGRFAM: photolyase PhrII YP_004370599.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR005170; KEGG: geo:Geob_3095 hypothetical protein; PFAM: cystathionine beta-synthase, core; transporter-associated domain; SMART: cystathionine beta-synthase, core; SPTR: hypothetical protein; PFAM: CBS domain; transporter associated domain YP_004370600.1 COGs: COG1586 S-adenosylmethionine decarboxylase; InterPro IPR003826:IPR017716; KEGG: sfu:Sfum_0720 S-adenosylmethionine decarboxylase related; PFAM: S-adenosylmethionine decarboxylase, bacterial/archaeal; SPTR: adenosylmethionine decarboxylase proenzyme; TIGRFAM: S-adenosylmethionine decarboxylase proenzyme; PFAM: S-adenosylmethionine decarboxylase; TIGRFAM: S-adenosylmethionine decarboxylase proenzyme, Bacillus form YP_004370601.1 InterPro IPR001387:IPR013096; KEGG: gme:Gmet_0901 XRE family transcriptional regulator; PFAM: Cupin 2, conserved barrel; Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: XRE family transcriptional regulator; PFAM: Cupin domain; Helix-turn-helix YP_004370602.1 KEGG: sfu:Sfum_0924 hypothetical protein; SPTR: uncharacterized protein YP_004370603.1 COGs: COG3357 transcriptional regulator protein; KEGG: geo:Geob_0940 transcriptional regulator; SPTR: transcriptional regulator; manually curated YP_004370604.1 COGs: COG1893 Ketopantoate reductase; InterPro IPR013332:IPR013752:IPR003710; KEGG: tye:THEYE_A1653 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, C-terminal; Ketopantoate reductase ApbA/PanE, N-terminal; PRIAM: 2-dehydropantoate 2-reductase; SPTR: 2-dehydropantoate 2-reductase; TIGRFAM: Ketopantoate reductase ApbA/PanE; PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase YP_004370605.1 KEGG: nam:NAMH_0394 hypothetical protein; SPTR: uncharacterized protein YP_004370606.1 COGs: COG0139 phosphoribosyl-AMP cyclohydrolase; HAMAP: phosphoribosyl-AMP cyclohydrolase; InterPro IPR002496; KEGG: dal:Dalk_3405 phosphoribosyl-AMP cyclohydrolase; PFAM: phosphoribosyl-AMP cyclohydrolase; PRIAM: phosphoribosyl-AMP cyclohydrolase; SPTR: phosphoribosyl-AMP cyclohydrolase; PFAM: phosphoribosyl-AMP cyclohydrolase YP_004370607.1 COGs: COG0040 ATP phosphoribosyltransferase; HAMAP: histidine biosynthesis HisG, ATP phosphoribosyltransferase, subgroup; InterPro IPR020621:IPR013820:IPR013115; KEGG: dma:DMR_00640 ATP phosphoribosyltransferase; PFAM: ATP phosphoribosyltransferase, catalytic domain; histidine biosynthesis HisG, C-terminal; PRIAM: ATP phosphoribosyltransferase; SPTR: ATP phosphoribosyltransferase 2; TIGRFAM: ATP phosphoribosyltransferase, catalytic domain; histidine biosynthesis HisG, C-terminal; PFAM: HisG, C-terminal domain; ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase, C-terminal domain; ATP phosphoribosyltransferase YP_004370608.1 KEGG: bma:BMA2996 hypothetical protein; SPTR: Conserved domain protein YP_004370609.1 InterPro IPR001440:IPR019734; KEGG: ter:Tery_2811 tetratricopeptide TPR_2; PFAM: Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_2 YP_004370610.1 COGs: COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: dol:Dole_0031 hypothetical protein; PFAM: Mammalian cell entry-related; SPTR: Mammalian cell entry related domain protein; PFAM: mce related protein YP_004370611.1 COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: fpl:Ferp_2487 histone deacetylase superfamily; PFAM: histone deacetylase superfamily; SPTR: histone deacetylase superfamily; PFAM: histone deacetylase domain YP_004370612.1 COGs: COG2078 conserved hypothetical protein; HAMAP: AMMECR1-domain protein; InterPro IPR002733; KEGG: sfu:Sfum_1996 AMMECR1 domain-containing protein; PFAM: AMMECR1; SPTR: AMMECR1 domain protein; TIGRFAM: AMMECR1; PFAM: AMMECR1; TIGRFAM: uncharacterized protein, PH0010 family YP_004370613.1 COGs: COG5345 conserved hypothetical protein; InterPro IPR016936; KEGG: dol:Dole_0654 hypothetical protein; PFAM: Uncharacterised conserved protein UCP029693; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2333) YP_004370614.1 InterPro IPR011449; KEGG: acr:Acry_3591 hypothetical protein; PFAM: PEP-CTERM bacterial; SPTR: uncharacterized protein YP_004370615.1 COGs: COG0517 FOG: CBS domain; InterPro IPR000644; KEGG: sfu:Sfum_2076 signal-transduction protein; PFAM: cystathionine beta-synthase, core; SMART: cystathionine beta-synthase, core; SPTR: signal-transduction protein with CBS domains; PFAM: CBS domain YP_004370616.1 COGs: COG0029 aspartate oxidase; InterPro IPR003953:IPR004112:IPR005288; KEGG: dal:Dalk_4332 L-aspartate oxidase; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: L-aspartate oxidase; SPTR: L-aspartate oxidase; TIGRFAM: L-aspartate oxidase; PFAM: domain; FAD binding domain; TIGRFAM: L-aspartate oxidase YP_004370617.1 KEGG: cak:Caul_4888 ribosomal protein S16; SPTR: 30S ribosomal protein S16 YP_004370618.1 KEGG: dbr:Deba_0321 hypothetical protein; SPTR: uncharacterized protein YP_004370619.1 COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: drm:Dred_1772 enoyl-CoA hydratase/isomerase; PFAM: Crotonase, core; SPTR: Short chain enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isomerase YP_004370620.1 COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR013656:IPR003661:IPR003594:IPR000014; KEGG: dbr:Deba_0030 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; SPTR: PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004370621.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: tna:CTN_1231 response regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator; PFAM: Response regulator receiver domain YP_004370622.1 COGs: COG0448 ADP-glucose pyrophosphorylase; HAMAP: glucose-1-phosphate adenylyltransferase GlgC, bacterial; InterPro IPR023049:IPR005835:IPR011831; KEGG: nde:NIDE1796 glucose-1-phosphate adenylyltransferase; PFAM: nucleotidyl transferase; PRIAM: glucose-1-phosphate adenylyltransferase; SPTR: glucose-1-phosphate adenylyltransferase; TIGRFAM: glucose-1-phosphate adenylyltransferase; PFAM: nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase YP_004370623.1 COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078:IPR017578; KEGG: glo:Glov_3084 alpha-ribazole phosphatase; PFAM: histidine phosphatase superfamily, clade-1; SMART: histidine phosphatase superfamily, clade-1; SPTR: Alpha-ribazole phosphatase; TIGRFAM: Alpha-ribazole phosphatase, CobC; PFAM: phosphoglycerate mutase; TIGRFAM: alpha-ribazole phosphatase YP_004370624.1 COGs: COG0394 protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: gme:Gmet_0521 protein tyrosine phosphatase; PFAM: protein-tyrosine phosphatase, low molecular weight; SMART: protein-tyrosine phosphatase, low molecular weight; SPTR: protein tyrosine phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase; TIGRFAM: arsenate reductase (thioredoxin) YP_004370625.1 InterPro IPR005243; KEGG: mma:MM_0737 hypothetical protein; SPTR: Conserved protein; TIGRFAM: Redox-active disulphide protein 2; TIGRFAM: small redox-active disulfide protein 2 YP_004370626.1 COGs: COG0785 Cytochrome c biogenesis protein; InterPro IPR003834; KEGG: gme:Gmet_0516 cytochrome c biogenesis protein, transmembrane region; PFAM: Cytochrome c assembly protein, transmembrane domain; SPTR: Cytochrome c biogenesis protein, transmembrane region; PFAM: Cytochrome C biogenesis protein transmembrane region YP_004370627.1 KEGG: gme:Gmet_0517 thioredoxin-related protein; SPTR: Thioredoxin domain protein; PFAM: Thioredoxin YP_004370628.1 COGs: COG0701 permease; InterPro IPR005524; KEGG: drt:Dret_1783 permease; PFAM: protein of unknown function DUF318, transmembrane; SPTR: Permease; PFAM: Predicted permease YP_004370629.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: gur:Gura_0468 regulatory protein, ArsR; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: ArsR family transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family YP_004370631.1 KEGG: zro:ZYRO0C17820g hypothetical protein; SPTR: Catalase YP_004370632.1 KEGG: tfu:Tfu_1907 hypothetical protein; SPTR: uncharacterized protein YP_004370633.1 COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650:IPR010182; KEGG: dbr:Deba_1163 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase M20, dimerisation; PRIAM: Succinyl-diaminopimelate desuccinylase; SPTR: Acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; TIGRFAM: Acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20/M25/M40; peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase YP_004370634.1 COGs: COG0421 Spermidine synthase; InterPro IPR013217; KEGG: kfl:Kfla_1557 spermine synthase; PFAM: methyltransferase type 12; SPTR: Spermine synthase; PFAM: Spermine/spermidine synthase YP_004370635.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: min:Minf_2443 ABC-type antimicrobial peptide transport system, ATPase component; PFAM: ABC transporter-like; PRIAM: phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter-related protein; PFAM: ABC transporter YP_004370636.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: chl:Chy400_0067 protein of unknown function DUF214; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004370637.1 COGs: COG2875 Precorrin-4 methylase; InterPro IPR000878; KEGG: dae:Dtox_0475 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases YP_004370638.1 COGs: COG4087 Soluble P-type ATPase; InterPro IPR005834; KEGG: dvm:DvMF_1180 hypothetical protein; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: uncharacterized protein; PFAM: haloacid dehalogenase-like hydrolase YP_004370639.1 COGs: COG0574 phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279; KEGG: tye:THEYE_A0726 probable phosphoenolpyruvate synthase; PFAM: pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile domain; PRIAM: pyruvate, water dikinase; SPTR: Probable phosphoenolpyruvate synthase; PFAM: PEP-utilising enzyme, mobile domain; pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: phosphoenolpyruvate synthase YP_004370640.1 COGs: COG2264 ribosomal protein L11 methylase; InterPro IPR010456; KEGG: dal:Dalk_1101 ribosomal L11 methyltransferase; PFAM: ribosomal L11 methyltransferase, PrmA; SPTR: ribosomal L11 methyltransferase; PFAM: ribosomal protein L11 methyltransferase (PrmA); TIGRFAM: ribosomal protein L11 methyltransferase YP_004370641.1 COGs: COG0350 methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: cow:Calow_0292 methylated-DNA/protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; SPTR: methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase YP_004370642.1 COGs: COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; HAMAP: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type; InterPro IPR004588; KEGG: sfu:Sfum_2112 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; PFAM: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type; SPTR: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; TIGRFAM: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type; PFAM: GcpE protein; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase YP_004370643.1 KEGG: vcn:VOLCADRAFT_85967 hypothetical protein; SPTR: uncharacterized protein YP_004370644.1 KEGG: cts:Ctha_0961 amine oxidase; SPTR: Leucine--tRNA ligase YP_004370645.1 KEGG: bfs:BF1017 acetyltransferase; SPTR: acetyltransferase YP_004370646.1 COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR005481:IPR005479:IPR005482:IPR004549; KEGG: tye:THEYE_A1738 acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; PRIAM: pyruvate carboxylase; SMART: Biotin carboxylase, C-terminal; SPTR: Acetyl-CoA carboxylase, biotin carboxylase; TIGRFAM: Acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit YP_004370647.1 COGs: COG5016 pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891; KEGG: tau:Tola_1848 pyruvate carboxylase subunit B; PFAM: pyruvate carboxyltransferase; PRIAM: oxaloacetate decarboxylase; SPTR: oxaloacetate decarboxylase alpha subunit; PFAM: HMGL-like; Conserved carboxylase domain YP_004370648.1 COGs: COG1355 dioxygenase; InterPro IPR002737; KEGG: dal:Dalk_4100 protein of unknown function DUF52; PFAM: UPF0103/Mediator of ErbB2-driven cell motility (Memo-related); SPTR: uncharacterized protein; PFAM: Memo-like protein YP_004370649.1 COGs: COG1492 cobyric acid synthase; HAMAP: cobyric acid synthase CobQ; InterPro IPR004459:IPR002586:IPR011698; KEGG: sfu:Sfum_1739 cobyric acid synthase CobQ; PFAM: CobB/CobQ-like glutamine amidotransferase; cobyrinic acid a,c-diamide synthase; SPTR: cobyric acid synthase; TIGRFAM: cobyric acid synthase CobQ; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyric acid synthase CobQ YP_004370650.1 COGs: COG1797 cobyrinic acid a c-diamide synthase; HAMAP: cobyrinic acid a,c-diamide synthase CbiA; InterPro IPR004484:IPR002586:IPR011698; KEGG: sfu:Sfum_4044 cobyrinic acid a,c-diamide synthase; PFAM: CobB/CobQ-like glutamine amidotransferase; cobyrinic acid a,c-diamide synthase; SPTR: cobyrinic acid A,C-diamide synthase; TIGRFAM: cobyrinic acid a,c-diamide synthase CbiA; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyrinic acid a,c-diamide synthase YP_004370651.1 KEGG: tye:THEYE_A1996 hypothetical protein; SPTR: Dissimilatory sulfite reductase subunit D (DsrD) YP_004370652.1 COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterPro IPR005117:IPR006067:IPR001450:IPR011808; KEGG: sfu:Sfum_4043 sulfite reductase, dissimilatory-type beta subunit; PFAM: nitrite/sulphite reductase 4Fe-4S domain; nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; 4Fe-4S binding domain; PRIAM: Hydrogensulfite reductase; SPTR: Sulfite reductase, dissimilatory-type beta subunit; TIGRFAM: Sulphite reductase, dissimilatory-type beta subunit; PFAM: nitrite and sulphite reductase 4Fe-4S domain; nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: sulfite reductase, dissimilatory-type beta subunit YP_004370653.1 COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterPro IPR006067:IPR011806; KEGG: dbr:Deba_0960 dissimilatory sulfite reductase alpha subunit; PFAM: nitrite/sulphite reductase 4Fe-4S domain; PRIAM: Hydrogensulfite reductase; SPTR: Dissimilatory sulfite reductase alpha subunit; TIGRFAM: Sulphite reductase, dissimilatory-type alpha subunit; PFAM: nitrite and sulphite reductase 4Fe-4S domain; nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit YP_004370654.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765:IPR007863; KEGG: afw:Anae109_1973 peptidase M16 domain-containing protein; PFAM: peptidase M16, C-terminal; peptidase M16, N-terminal; SPTR: peptidase M16 domain protein; PFAM: peptidase M16 inactive domain; Insulinase (peptidase M16) YP_004370656.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765:IPR007863; KEGG: ade:Adeh_1867 peptidase M16-like; PFAM: peptidase M16, C-terminal; peptidase M16, N-terminal; SPTR: peptidase M16-like protein; PFAM: peptidase M16 inactive domain; Insulinase (peptidase M16) YP_004370657.1 COGs: COG2984 ABC transporter periplasmic component; KEGG: plm:Plim_2859 protein of unknown function DUF534; SPTR: uncharacterized protein; PFAM: ABC transporter substrate binding protein YP_004370658.1 COGs: COG0681 Signal peptidase I; InterPro IPR019759:IPR000223; KEGG: tye:THEYE_A0098 signal peptidase I; PFAM: peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Signal peptidase I; TIGRFAM: peptidase S26A, signal peptidase I; PFAM: peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type YP_004370659.1 COGs: COG0481 Membrane GTPase LepA; HAMAP: GTP-binding protein LepA; InterProIPR006297:IPR000795:IPR004161:IPR000640:IPR 013842:IPR005225; KEGG: ddf:DEFDS_0116 GTP-binding protein LepA; PFAM: protein synthesis factor, GTP-binding; translation elongation factor EFTu/EF1A, domain 2; translation elongation factor EFG/EF2, C-terminal; GTP-binding protein LepA, C-terminal; SMART: translation elongation factor EFG/EF2, C-terminal; SPTR: GTP-binding protein lepA; TIGRFAM: GTP-binding protein LepA; Small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; GTP-binding protein LepA C-terminus; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein domain YP_004370660.1 COGs: COG0546 phosphatase; InterPro IPR005834:IPR006402:IPR006439; KEGG: dak:DaAHT2_2039 HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E YP_004370661.1 COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR005110:IPR001453:IPR005111:IPR020817; KEGG: sfu:Sfum_0615 molybdenum cofactor synthesis domain-containing protein; PFAM: Molybdopterin binding; MoeA, N-terminal and linker domain; MoeA, C-terminal, domain IV; SMART: Molybdopterin binding; SPTR: uncharacterized protein; TIGRFAM: Molybdenum cofactor synthesis; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain YP_004370662.1 KEGG: ter:Tery_3981 PEP motif-containing protein; SPTR: uncharacterized protein YP_004370663.1 KEGG: nda:Ndas_1354 GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase YP_004370664.1 InterPro IPR006016; KEGG: tgr:Tgr7_3238 universal stress protein; PFAM: UspA; SPTR: uncharacterized protein; PFAM: Universal stress protein family YP_004370665.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: geo:Geob_2117 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase YP_004370666.1 KEGG: vei:Veis_0670 hypothetical protein; SPTR: uncharacterized protein YP_004370667.1 KEGG: vei:Veis_0670 hypothetical protein; SPTR: uncharacterized protein YP_004370668.1 COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: tma:TM0630 nucleotide sugar epimerase, PFAM: NAD-dependent epimerase/dehydratase; PRIAM: dTDP-glucose 4,6-dehydratase; SPTR: nucleotide sugar epimerase, ; PFAM: NAD dependent epimerase/dehydratase YP_004370669.1 InterPro IPR002559; KEGG: app:CAP2UW1_3182 transposase IS4 family protein; PFAM: transposase, IS4-like; SPTR: transposase IS4 family protein; PFAM: transposase DDE domain YP_004370670.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR013154:IPR013149:IPR000683:IPR020843; KEGG: tye:THEYE_A0496 oxidoreductase; PFAM: Oxidoreductase, N-terminal; Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; SMART: polyketide synthase, enoylreductase; SPTR: Oxidoreductase; PFAM: Oxidoreductase, NAD-binding Rossmann fold; Zinc-binding dehydrogenase YP_004370671.1 KEGG: ttj:TTHA1223 hypothetical protein; SPTR: Apolipoprotein A1/A4/E YP_004370672.1 KEGG: hth:HTH_1447 hypothetical protein; SPTR: uncharacterized protein YP_004370673.1 KEGG: eoh:ECO103_1856 hypothetical protein; SPTR: uncharacterized protein YP_004370674.1 KEGG: ttj:TTHA1223 hypothetical protein; SPTR: Apolipoprotein A1/A4/E YP_004370675.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509:IPR014344; KEGG: gme:Gmet_2005 polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: polysaccharide deacetylase; TIGRFAM: PEP-CTERM locus, polysaccharide deactylase; PFAM: Domain of unknown function (DUF3473); polysaccharide deacetylase; TIGRFAM: polysaccharide deactylase, PEP-CTERM locus subfamily YP_004370676.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: tma:TM0631 lipopolysaccharide biosynthesis protein; PFAM: glycosyl transferase, group 1; SPTR: Lipopolysaccharide biosynthesis protein; PFAM: glycosyl transferases group 1 YP_004370677.1 COGs: COG3919 ATP-grasp protein; InterPro IPR003806; KEGG: mem:Memar_1598 ATP-grasp enzyme-like protein; PFAM: ATP-grasp fold, DUF201-type; SPTR: uncharacterized protein; PFAM: ATP-grasp domain YP_004370678.1 COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR004013:IPR003141; KEGG: ttm:Tthe_2569 PHP domain protein; PFAM: PHP, C-terminal; SMART: polymerase/histidinol phosphatase, N-terminal; SPTR: PHP domain protein; PFAM: PHP domain YP_004370679.1 COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013216; KEGG: lil:LA_2661 methylase/methyltransferase; PFAM: methyltransferase type 11; SPTR: methylase/methyltransferase; PFAM: methyltransferase domain YP_004370680.1 InterPro IPR012933; KEGG: dak:DaAHT2_2044 YcfA family protein; PFAM: Uncharacterised protein family UPF0395; SPTR: YcfA family protein; manually curated; PFAM: YcfA-like protein YP_004370681.1 KEGG: dak:DaAHT2_2043 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0150) YP_004370682.1 COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013216; KEGG: shl:Shal_1398 methyltransferase type 12; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; PFAM: methyltransferase domain YP_004370683.1 InterPro IPR001173; KEGG: sli:Slin_2590 glycosyl transferase 2; PFAM: glycosyl transferase, family 2; SPTR: glycosyl transferase 2; PFAM: glycosyl transferase 2 YP_004370684.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: ade:Adeh_3055 glycosyl transferase, group 1; PFAM: glycosyl transferase, group 1; SPTR: glycosyl transferase, group 1; PFAM: glycosyl transferases group 1 YP_004370685.1 KEGG: fri:FraEuI1c_2244 hypothetical protein; SPTR: uncharacterized protein YP_004370686.1 COGs: COG4641 conserved hypothetical protein; KEGG: fri:FraEuI1c_2243 hypothetical protein; SPTR: uncharacterized protein YP_004370687.1 COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013217; KEGG: mem:Memar_0201 methyltransferase type 12; PFAM: methyltransferase type 12; SPTR: methyltransferase type 12; PFAM: methyltransferase domain YP_004370688.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: ade:Adeh_2772 glycosyl transferase, group 1; PFAM: glycosyl transferase, group 1; SPTR: glycosyl transferase, group 1; PFAM: glycosyl transferases group 1 YP_004370689.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: acp:A2cp1_0958 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; PFAM: methyltransferase domain YP_004370690.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: gme:Gmet_1490 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein YP_004370691.1 COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: glo:Glov_0772 lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase, family 9; SPTR: Lipopolysaccharide heptosyltransferase II; PFAM: glycosyltransferase 9 (heptosyltransferase) YP_004370692.1 COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR000583:IPR001962:IPR006426; KEGG: cyn:Cyan7425_4960 asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; glutamine amidotransferase, class-II; PRIAM: Asparagine synthase (glutamine-hydrolyzing); SPTR: Asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing) YP_004370693.1 KEGG: pna:Pnap_0062 hypothetical protein; SPTR: uncharacterized protein; PFAM: PIN domain YP_004370694.1 KEGG: rcu:RCOM_0591290 hypothetical protein; SPTR: uncharacterized protein YP_004370696.1 InterPro IPR007712; KEGG: bgl:bglu_1g12000 hypothetical protein; PFAM: Plasmid stabilisation system; SPTR: uncharacterized protein; PFAM: Plasmid stabilisation system protein YP_004370697.1 KEGG: mhu:Mhun_0503 hypothetical protein; SPTR: Similarity YP_004370698.1 KEGG: nwa:Nwat_2922 plasmid stabilization system; SPTR: Plasmid stabilization system YP_004370699.1 KEGG: cpo:COPRO5265_0993 preprotein translocase, SecY subunit; SPTR: Protease Do-like 10, mitochondrial YP_004370700.1 InterPro IPR007712; KEGG: dal:Dalk_2443 hypothetical protein; PFAM: Plasmid stabilisation system; SPTR: uncharacterized protein; PFAM: Plasmid stabilisation system protein; TIGRFAM: addiction module toxin, RelE/StbE family YP_004370701.1 KEGG: bts:Btus_2922 hypothetical protein; SPTR: uncharacterized protein YP_004370702.1 InterPro IPR005357; KEGG: mma:MM_0031 hypothetical protein; PFAM: Uncharacterised protein family UPF0150; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0150) YP_004370703.1 COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR003594; KEGG: sfu:Sfum_2709 histidine kinase; PFAM: ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; SPTR: histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004370704.1 KEGG: lif:LinJ35.0630 proteophosphoglycan ppg4; SPTR: Proteophosphoglycan ppg4 YP_004370705.1 COGs: COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I C-terminal domain; InterPro IPR004647; KEGG: pth:PTH_1357 fumarase C-terminal domain-containing protein; PFAM: Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; PRIAM: Fumarate hydratase; SPTR: Fumarase, C-terminal domain; TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; PFAM: Fumarase C-terminus; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region YP_004370706.1 COGs: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I N-terminal domain; InterPro IPR004646; KEGG: cno:NT01CX_2052 fumarate hydratase; PFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; PRIAM: Fumarate hydratase; SPTR: Tartrate dehydratase subunit alpha; TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; PFAM: Fumarate hydratase (Fumerase); TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region YP_004370707.1 COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460:IPR011816; KEGG: dal:Dalk_4811 penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: peptidoglycan glycosyltransferase; SPTR: uncharacterized protein; TIGRFAM: Penicillin-binding protein 1A; PFAM: Penicillin binding protein transpeptidase domain; transglycosylase; TIGRFAM: penicillin-binding protein, 1A family YP_004370708.1 COGs: COG0223 methionyl-tRNA formyltransferase; InterPro IPR002376:IPR005793; KEGG: bfo:BRAFLDRAFT_290865 hypothetical protein; PFAM: formyl transferase, N-terminal; formyl transferase, C-terminal; PRIAM: formyltetrahydrofolate dehydrogenase; SPTR: uncharacterized protein; PFAM: formyl transferase; formyl transferase, C-terminal domain YP_004370709.1 KEGG: aoe:Clos_2486 hypothetical protein; SPTR: uncharacterized protein YP_004370710.1 COGs: COG0008 glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR020058:IPR004527; KEGG: sfu:Sfum_1366 glutamyl-tRNA synthetase; PFAM: glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; PRIAM: glutamate--tRNA ligase; SPTR: glutamyl-tRNA synthetase; TIGRFAM: glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-tRNA synthetase, bacterial family YP_004370711.1 COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136; KEGG: sdl:Sdel_0649 2-nitropropane dioxygenase NPD; PFAM: 2-nitropropane dioxygenase, NPD; SPTR: 2-nitropropane dioxygenase NPD; PFAM: 2-nitropropane dioxygenase YP_004370712.1 COGs: COG1182 acyl carrier protein phosphodiesterase; HAMAP: NADH-azoreductase, FMN-dependent; InterPro IPR023048:IPR003680; KEGG: dvl:Dvul_0699 (acyl-carrier-protein) phosphodiesterase; PFAM: Flavodoxin-like fold; SPTR: FMN-dependent NADH-azoreductase; PFAM: Flavodoxin-like fold YP_004370713.1 COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: rci:RRC90 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: 4Fe-4S ferredoxin-domain protein (NADPH-dependent FMN reductase); PFAM: NADPH-dependent FMN reductase YP_004370714.1 KEGG: dbr:Deba_3221 deoxyribose-phosphate aldolase; SPTR: Deoxyribose-phosphate aldolase YP_004370715.1 InterPro IPR007712; KEGG: dak:DaAHT2_1852 plasmid stabilization system; PFAM: Plasmid stabilisation system; SPTR: Plasmid stabilization system; PFAM: Plasmid stabilisation system protein YP_004370716.1 KEGG: dae:Dtox_2459 hypothetical protein; SPTR: uncharacterized protein YP_004370717.1 KEGG: cyn:Cyan7425_2664 4Fe-4S ferredoxin, iron-sulfur binding; SPTR: Cytochrome c3 hydrogenase alpha (Or beta) chain YP_004370718.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: rmr:Rmar_2587 Crp/Fnr family transcriptional regulator; PFAM: Cyclic nucleotide-binding domain; SMART: Cyclic nucleotide-binding domain; SPTR: Crp/Fnr family transcriptional regulator; PFAM: Cyclic nucleotide-binding domain YP_004370719.1 COGs: COG1941 Coenzyme F420-reducing hydrogenase gamma subunit; InterPro IPR006137; KEGG: cyn:Cyan7425_2661 NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; SPTR: NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit YP_004370720.1 COGs: COG3259 Coenzyme F420-reducing hydrogenase alpha subunit; InterPro IPR001501; KEGG: rmr:Rmar_2590 nickel-dependent hydrogenase large subunit; PFAM: Nickel-dependent hydrogenase, large subunit; PRIAM: Hydrogen dehydrogenase; SPTR: uncharacterized protein; PFAM: Nickel-dependent hydrogenase YP_004370721.1 KEGG: cyh:Cyan8802_2220 hypothetical protein; SPTR: uncharacterized protein YP_004370722.1 InterPro IPR000086; KEGG: dak:DaAHT2_0985 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase; PFAM: NUDIX domain YP_004370724.1 KEGG: dau:Daud_1829 DNA binding domain-containing protein; SPTR: DNA binding domain, excisionase YP_004370725.1 COGs: COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; InterPro IPR007712:IPR012753; KEGG: alv:Alvin_1697 addiction module toxin, RelE/StbE family; PFAM: Plasmid stabilisation system; SPTR: Addiction module toxin, RelE/StbE family; TIGRFAM: Addiction module toxin, RelE/StbE; PFAM: Plasmid stabilisation system protein YP_004370726.1 InterPro IPR006442; KEGG: sti:Sthe_3417 prevent-host-death family protein; PFAM: Prevent-host-death protein; SPTR: uncharacterized protein; TIGRFAM: Prevent-host-death protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein YP_004370727.1 COGs: COG0426 flavoprotein; InterPro IPR001279; KEGG: dat:HRM2_00830 metallo-beta-lactamase (IMP dehydrogenase/GMP reductase:beta-lactamase-like); PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily YP_004370728.1 COGs: COG3189 conserved hypothetical protein; InterPro IPR007438; KEGG: sfu:Sfum_3731 hypothetical protein; PFAM: protein of unknown function DUF488; SPTR: uncharacterized protein; PFAM: protein of unknown function, DUF488 YP_004370729.1 InterPro IPR001450; KEGG: drt:Dret_0154 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: protein of unknown function (DUF1271) YP_004370730.1 InterPro IPR013096; KEGG: dal:Dalk_1201 cupin; PFAM: Cupin 2, conserved barrel; SPTR: cupin; PFAM: Cupin domain YP_004370731.1 COGs: COG1309 transcriptional regulator; InterPro IPR001647; KEGG: dal:Dalk_0754 TetR family transcriptional regulator; PFAM: transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: TetR family transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family; YsiA-like protein, C-terminal region YP_004370732.1 COGs: COG0605 Superoxide dismutase; InterPro IPR019832; KEGG: gsu:GSU1158 superoxide dismutase; PFAM: Manganese/iron superoxide dismutase, C-terminal; SPTR: Superoxide dismutase; PFAM: Iron/manganese superoxide dismutases, alpha-hairpin domain; Iron/manganese superoxide dismutases, C-terminal domain YP_004370734.1 KEGG: dia:Dtpsy_2978 D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase YP_004370735.1 InterPro IPR005490; KEGG: cpi:Cpin_0914 ErfK/YbiS/YcfS/YnhG family protein; PFAM: YkuD domain; SPTR: uncharacterized protein; PFAM: L,D-transpeptidase catalytic domain YP_004370736.1 KEGG: cyj:Cyan7822_4952 hypothetical protein; SPTR: uncharacterized protein YP_004370737.1 KEGG: srm:SRM_03082 conserved hypothetical protein, secreted; SPTR: uncharacterized protein YP_004370738.1 KEGG: sru:SRU_2867 hypothetical protein; SPTR: uncharacterized protein YP_004370739.1 KEGG: mag:amb2412 cell wall hydrolyses involved in spore germination; SPTR: Cell wall hydrolyses involved in spore germination; PFAM: Cell Wall Hydrolase YP_004370740.1 KEGG: sat:SYN_02246 cytoplasmic protein; SPTR: Hypothetical cytosolic protein YP_004370741.1 KEGG: sat:SYN_02254 cytoplasmic protein; SPTR: uncharacterized protein; manually curated; PFAM: Uncharacterized conserved protein (DUF2276) YP_004370742.1 COGs: COG1353 hydrolase of the HD superfamily (permuted catalytic motifs); InterPro IPR000160:IPR013408; KEGG: saf:SULAZ_1602 crispr-associated protein, Csm1 family; PFAM: Diguanylate cyclase, predicted; SPTR: uncharacterized protein; TIGRFAM: CRISPR-associated protein Csm1; TIGRFAM: CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE YP_004370743.1 InterPro IPR010149; KEGG: mru:mru_1182 CRISPR-associated protein Csm2 family; PFAM: CRISPR-associated protein, TM1810 C-terminal; SPTR: uncharacterized protein; TIGRFAM: CRISPR-associated protein, TM1810 C-terminal; PFAM: protein of unknown function (DUF310); TIGRFAM: CRISPR type III-A/MTUBE-associated protein Csm2 YP_004370744.1 COGs: COG1337 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR005537:IPR013412; KEGG: saf:SULAZ_1604 crispr-associated RAMP protein, Csm3 family; PFAM: protein of unknown function DUF324; SPTR: Uncharacterized protein MTH_1080; TIGRFAM: CRISPR-associated RAMP Csm3; PFAM: RAMP superfamily; TIGRFAM: CRISPR type III-A/MTUBE-associated RAMP protein Csm3 YP_004370745.1 COGs: COG1567 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); KEGG: saf:SULAZ_1605 crispr-associated RAMP protein, Csm4 family; SPTR: uncharacterized protein; TIGRFAM: CRISPR type III-A/MTUBE-associated RAMP protein Csm4 YP_004370746.1 COGs: COG1332 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR005537:IPR010173; KEGG: saf:SULAZ_1607 crispr-associated RAMP protein, Csm5 family; PFAM: protein of unknown function DUF324; SPTR: uncharacterized protein; TIGRFAM: CRISPR-associated protein, TM1807; PFAM: RAMP superfamily; TIGRFAM: CRISPR type III-A/MTUBE-associated RAMP protein Csm5 YP_004370747.1 InterPro IPR013442; KEGG: alv:Alvin_3127 CRISPR-associated protein, APE2256 family; PFAM: CRISPR-associated protein APE2256; SPTR: uncharacterized protein; PFAM: CRISPR-associated protein (Cas_APE2256); TIGRFAM: CRISPR-associated protein, APE2256 family YP_004370748.1 COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: mem:Memar_1228 DNA polymerase beta subunit; PFAM: nucleotidyl transferase domain; SPTR: uncharacterized protein; PFAM: nucleotidyltransferase domain YP_004370749.1 KEGG: sfu:Sfum_1351 hypothetical protein; SPTR: Uncharacterized protein MJ1673 YP_004370750.1 InterPro IPR011742:IPR013383; KEGG: sfu:Sfum_1352 CRISPR-associated TM1812 family protein; PFAM: CRISPR-associated protein, TM1812; SPTR: CRISPR-associated protein, Csx2 family; TIGRFAM: CRISPR-associated protein, TM1812; CRISPR-associated protein DxTHG, conserved site; PFAM: CRISPR-associated protein (cas_TM1812); TIGRFAM: CRISPR-associated protein, TM1812 family; CRISPR-associated DxTHG motif protein YP_004370751.1 KEGG: npu:Npun_F3820 hypothetical protein; SPTR: uncharacterized protein; PFAM: transposase IS200 like YP_004370752.1 KEGG: ilo:IL0808 recombinational DNA repair protein RecO, RecF pathway; SPTR: ABC-type sugar transport system, periplasmic component YP_004370753.1 KEGG: ton:TON_0225 hypothetical protein; SPTR: uncharacterized protein; PFAM: PemK-like protein YP_004370754.1 COGs: COG4951 conserved hypothetical protein; InterPro IPR013105; KEGG: sfu:Sfum_1354 hypothetical protein; PFAM: Tetratricopeptide TPR2; SPTR: uncharacterized protein YP_004370755.1 InterPro IPR008815; KEGG: xca:xccb100_0546 hypothetical protein; PFAM: 23S rRNA-associated protein; SPTR: uncharacterized protein; manually curated; PFAM: S23 ribosomal protein YP_004370756.1 COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002729; KEGG: hau:Haur_2483 CRISPR-associated Cas1 family protein; PFAM: CRISPR-associated protein Cas1; SPTR: uncharacterized protein; TIGRFAM: CRISPR-associated protein Cas1; PFAM: CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated endonuclease Cas1 YP_004370757.1 COGs: COG1343 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR021127; KEGG: aar:Acear_0822 CRISPR-associated protein, Cas2 family; SPTR: CRISPR-associated protein, Cas2 family; TIGRFAM: CRISPR associated protein Cas2; PFAM: CRISPR associated protein Cas2; TIGRFAM: CRISPR-associated endoribonuclease Cas2 YP_004370758.1 InterPro IPR008815; KEGG: cli:Clim_1904 S23 ribosomal protein; PFAM: 23S rRNA-associated protein; SPTR: S23 ribosomal protein; PFAM: S23 ribosomal protein YP_004370759.1 COGs: COG1042 acyl-CoA synthetase (NDP forming); InterPro IPR003781; KEGG: sfu:Sfum_2466 CoA-binding domain-containing protein; PFAM: CoA-binding; SMART: CoA-binding; SPTR: CoA-binding domain protein; PFAM: CoA binding domain YP_004370760.1 COGs: COG0419 ATPase involved in DNA repair; KEGG: sat:SYN_02754 DNA repair ATPase; SPTR: ATPases involved in DNA repair YP_004370761.1 COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: mhu:Mhun_3236 transcriptional regulator; PFAM: ATPase, AAA-4; SPTR: uncharacterized protein; PFAM: Divergent AAA domain YP_004370762.1 COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR002300:IPR013155:IPR002302; KEGG: ppd:Ppro_1731 leucyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ia; Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; PRIAM: Leucine--tRNA ligase; SPTR: Leucyl-tRNA synthetase; TIGRFAM: Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family YP_004370763.1 KEGG: gur:Gura_3133 hypothetical protein; SPTR: Lipoprotein YP_004370764.1 COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR010372:IPR005790; KEGG: tjr:TherJR_2462 DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta; SPTR: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit YP_004370765.1 HAMAP: ribosomal protein S20; InterPro IPR002583; KEGG: dak:DaAHT2_0446 ribosomal protein S20; PFAM: ribosomal protein S20; SPTR: 30S ribosomal protein S20; TIGRFAM: ribosomal protein S20; PFAM: ribosomal protein S20; TIGRFAM: ribosomal protein S20 YP_004370766.1 InterPro IPR006674; KEGG: dvl:Dvul_1712 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SPTR: HD domain protein; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG YP_004370767.1 COGs: COG0583 transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: sfu:Sfum_3313 LysR family transcriptional regulator; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: LysR family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain YP_004370768.1 COGs: COG1335 Amidase related to nicotinamidase; InterPro IPR000868; KEGG: dbr:Deba_1191 isochorismatase hydrolase; PFAM: Isochorismatase-like; SPTR: Isochorismatase hydrolase; PFAM: Isochorismatase YP_004370769.1 COGs: COG0466 ATP-dependent Lon protease; InterProIPR003111:IPR003959:IPR008269:IPR003593:IPR 004815; KEGG: dak:DaAHT2_2246 ATP-dependent protease La; PFAM: peptidase S16, Lon C-terminal; peptidase S16, lon N-terminal; ATPase, AAA-type, core; PRIAM: Endopeptidase La; SMART: peptidase S16, lon N-terminal; ATPase, AAA+ type, core; SPTR: ATP-dependent protease La; TIGRFAM: peptidase S16, ATP-dependent protease La; PFAM: ATP-dependent protease La (LON) domain; ATPase associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La YP_004370770.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR002550:IPR000644:IPR005170; KEGG: tth:TTC0382 hemolysin-like protein; PFAM: cystathionine beta-synthase, core; Domain of unknown function DUF21; transporter-associated domain; SMART: cystathionine beta-synthase, core; SPTR: Probable hemolysin-related protein/hypothetical protein; PFAM: CBS domain; Domain of unknown function DUF21; transporter associated domain YP_004370771.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR002550:IPR000644:IPR005170; KEGG: aar:Acear_0620 protein of unknown function DUF21; PFAM: Domain of unknown function DUF21; cystathionine beta-synthase, core; transporter-associated domain; SPTR: uncharacterized protein; PFAM: CBS domain; Domain of unknown function DUF21; transporter associated domain YP_004370772.1 COGs: COG1641 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0272; InterPro IPR002822; KEGG: sfu:Sfum_2531 hypothetical protein; PFAM: Uncharacterised protein family UPF0272; SPTR: UPF0272 protein GM18DRAFT_2292; TIGRFAM: Uncharacterised protein family UPF0272; PFAM: protein of unknown function DUF111; TIGRFAM: TIGR00299 family protein YP_004370773.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910:IPR000531; KEGG: ppd:Ppro_1253 TonB-dependent receptor, plug; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: TonB-dependent receptor, plug; PFAM: TonB-dependent Receptor Plug Domain YP_004370774.1 COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: mhu:Mhun_0224 FMN-binding protein; PFAM: Flavin reductase-like, FMN-binding; SMART: Flavin reductase-like, FMN-binding; SPTR: Fmn-binding protein; PFAM: Flavin reductase like domain YP_004370775.1 COGs: COG2875 Precorrin-4 methylase; InterPro IPR000878; KEGG: dae:Dtox_0475 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases YP_004370776.1 COGs: COG5266 ABC-type Co2+ transport system periplasmic component; InterPro IPR019613; KEGG: dbr:Deba_1637 nickel transport complex, NikM subunit, transmembrane; PFAM: Nickel transport complex, NikM subunit, transmembrane; SPTR: uncharacterized protein; PFAM: Nickel uptake substrate-specific transmembrane region YP_004370777.1 COGs: COG0531 Amino acid transporter; InterPro IPR004841; KEGG: ppd:Ppro_1252 amino acid permease-associated region; PFAM: Amino acid permease domain; SPTR: Amino acid permease-associated region; PFAM: Amino acid permease YP_004370778.1 InterPro IPR005358; KEGG: scl:sce5418 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: uncharacterized protein YP_004370779.1 COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: dvm:DvMF_1572 flavin reductase domain protein FMN-binding; PFAM: Flavin reductase-like, FMN-binding; SMART: Flavin reductase-like, FMN-binding; SPTR: Flavin reductase domain protein FMN-binding; PFAM: Flavin reductase like domain YP_004370780.1 KEGG: pno:SNOG_02682 hypothetical protein; SPTR: uncharacterized protein YP_004370781.1 COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: sfu:Sfum_3557 silent information regulator protein Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Silent information regulator protein Sir2; PFAM: Sir2 family YP_004370782.1 KEGG: dal:Dalk_4351 hypothetical protein; SPTR: uncharacterized protein YP_004370783.1 COGs: COG1042 acyl-CoA synthetase (NDP forming); InterPro IPR003781; KEGG: sat:SYN_02112 acetyl-CoA synthetase beta subunit; PFAM: CoA-binding; SMART: CoA-binding; SPTR: Acetyl-CoA synthetase beta subunit; PFAM: CoA binding domain YP_004370784.1 COGs: COG0557 Exoribonuclease R; InterPro IPR001900; KEGG: dol:Dole_0448 exoribonuclease II; PFAM: ribonuclease II/R; SMART: ribonuclease II/R; SPTR: Exoribonuclease II; PFAM: RNB domain; TIGRFAM: VacB and RNase II family 3'-5' exoribonucleases YP_004370785.1 COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: rca:Rcas_1812 metallophosphoesterase; PFAM: Metallo-dependent phosphatase; SPTR: Metallophosphoesterase; TIGRFAM: phosphodiesterase MJ0936; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family YP_004370786.1 InterPro IPR000182; KEGG: rrs:RoseRS_4349 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family YP_004370787.1 COGs: COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis; InterPro IPR003856:IPR005702; KEGG: nhl:Nhal_1315 capsular exopolysaccharide family; PFAM: Lipopolysaccharide biosynthesis; PRIAM: Non-specific protein-tyrosine kinase; SPTR: Capsular exopolysaccharide family; TIGRFAM: Exopolysaccharide synthesis protein; PFAM: Chain length determinant protein; CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: capsular exopolysaccharide family YP_004370788.1 COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR003715:IPR019554; KEGG: dol:Dole_1658 polysaccharide export protein; PFAM: polysaccharide export protein; Soluble ligand binding domain; SPTR: polysaccharide export protein; PFAM: polysaccharide biosynthesis/export protein; SLBB domain YP_004370789.1 InterPro IPR007016; KEGG: nhl:Nhal_1319 binding-protein-dependent transport system protein; PFAM: O-antigen ligase-related; SPTR: uncharacterized protein; PFAM: O-Antigen ligase YP_004370790.1 KEGG: spe:Spro_2887 carbohydrate-binding CenC domain-containing protein; SPTR: Carbohydrate-binding CenC domain-containing protein YP_004370791.1 KEGG: dat:HRM2_25550 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2320); TIGRFAM: uncharacterized protein, PEP-CTERM system associated YP_004370792.1 KEGG: bfo:BRAFLDRAFT_102370 hypothetical protein; SPTR: uncharacterized protein YP_004370793.1 COGs: COG4783 Zn-dependent protease contains TPR repeats; InterPro IPR001440:IPR013105:IPR019734; KEGG: mba:Mbar_A2893 O-linked N-acetylglucosamine transferase; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: O-linked N-acetylglucosamine transferase; PFAM: Tetratricopeptide repeat YP_004370794.1 COGs: COG0250 transcription antiterminator; InterPro IPR006645; KEGG: sfu:Sfum_1699 NusG antitermination factor; PFAM: transcription antitermination protein, NusG, N-terminal; SMART: transcription antitermination protein, NusG, N-terminal; SPTR: NusG antitermination factor; PFAM: transcription termination factor nusG YP_004370795.1 COGs: COG0574 phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279; KEGG: sfu:Sfum_0630 pyruvate, water dikinase; PFAM: pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile domain; PRIAM: pyruvate, water dikinase; SPTR: phosphoenolpyruvate synthase; manually curated; PFAM: PEP-utilising enzyme, mobile domain; pyruvate phosphate dikinase, PEP/pyruvate binding domain YP_004370796.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: tye:THEYE_A0725 FrgC; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: FrgC; PFAM: Response regulator receiver domain YP_004370797.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: tye:THEYE_A0725 FrgC; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: FrgC; PFAM: Response regulator receiver domain YP_004370798.1 COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004010:IPR013656:IPR003661:IPR003594:IPR 000014; KEGG: tye:THEYE_A0724 sensory box sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; Cache; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; SPTR: Sensory box sensor histidine kinase; TIGRFAM: PAS; PFAM: Cache domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004370799.1 InterPro IPR000638; KEGG: pin:Ping_1262 gas vesicle protein GVPa; PFAM: gas vesicle protein GvpA; SPTR: gas vesicle protein; PFAM: gas vesicle protein YP_004370800.1 InterPro IPR007805; KEGG: pin:Ping_1261 gas vesicle protein K; PFAM: gas vesicle protein GvpK; SPTR: gas vesicle protein K; PFAM: gas vesicle protein K YP_004370801.1 InterPro IPR000638; KEGG: mxa:MXAN_2767 GvpA family gas vesicle protein; PFAM: gas vesicle protein GvpA; SPTR: gas vesicle protein, GvpA family; PFAM: gas vesicle protein YP_004370802.1 COGs: COG0003 ATPase involved in chromosome partitioning; InterPro IPR003348; KEGG: gur:Gura_2829 arsenite-activated ATPase ArsA; PRIAM: Arsenite-transporting ATPase; SPTR: Arsenite-activated ATPase ArsA; TIGRFAM: ATPase, anion-transporting; PFAM: Anion-transporting ATPase; TIGRFAM: arsenite-activated ATPase ArsA YP_004370803.1 InterPro IPR007804; KEGG: mxa:MXAN_2768 gas vesicle protein GvpG; SPTR: uncharacterized protein; PFAM: gas vesicle protein G YP_004370804.1 InterPro IPR009430; KEGG: pin:Ping_1258 gas vesicle synthesis GvpLGvpF; PFAM: gas vesicle protein GvpL/GvpF; SPTR: uncharacterized protein; PFAM: gas vesicle synthesis protein GvpL/GvpF YP_004370805.1 KEGG: pin:Ping_1752 hypothetical protein; SPTR: uncharacterized protein YP_004370806.1 KEGG: mxa:MXAN_7281 CRISPR-associated Cmr2 family protein; SPTR: uncharacterized protein YP_004370807.1 KEGG: pin:Ping_1751 hypothetical protein; SPTR: uncharacterized protein YP_004370808.1 COGs: COG0714 MoxR-like ATPase; InterPro IPR011704:IPR003593:IPR013462; KEGG: pin:Ping_1750 gas vesicle protein GvpN; PFAM: ATPase, AAA-5; SMART: ATPase, AAA+ type, core; SPTR: gas vesicle protein gvpN; TIGRFAM: gas vesicle protein GvpN; PFAM: AAA domain (dynein-related subfamily); TIGRFAM: gas vesicle protein GvpN YP_004370809.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; KEGG: eba:ebA3490 hypothetical protein; SPTR: Chaperone protein dnaJ 1 YP_004370810.1 KEGG: kse:Ksed_07320 hypothetical protein; SPTR: uncharacterized protein YP_004370811.1 HAMAP: gas vesicle structural protein; InterPro IPR000638; KEGG: pin:Ping_1748 gas vesicle synthesis protein GvpA; PFAM: gas vesicle protein GvpA; SPTR: gas vesicle structural protein; PFAM: gas vesicle protein YP_004370812.1 KEGG: tcr:509805.70 hypothetical protein; SPTR: uncharacterized protein YP_004370813.1 HAMAP: gas vesicle structural protein; InterPro IPR000638; KEGG: pin:Ping_1748 gas vesicle synthesis protein GvpA; PFAM: gas vesicle protein GvpA; SPTR: gas vesicle structural protein; PFAM: gas vesicle protein YP_004370814.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: pin:Ping_1747 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain YP_004370815.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR013767:IPR003661:IPR003594:IPR 000014; KEGG: pin:Ping_1746 sensor histidine kinase PAS domain-containing protein; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; PAS fold-4; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; SPTR: uncharacterized protein; TIGRFAM: PAS; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004370816.1 InterPro IPR009430; KEGG: mxa:MXAN_2771 GvpL/GvpF family gas vesicle protein; PFAM: gas vesicle protein GvpL/GvpF; SPTR: gas vesicle protein, GvpL/GvpF family; PFAM: gas vesicle synthesis protein GvpL/GvpF YP_004370817.1 InterPro IPR009430; KEGG: pin:Ping_1248 gas vesicle synthesis GvpLGvpF; PFAM: gas vesicle protein GvpL/GvpF; SPTR: gas vesicle synthesis GvpLGvpF; PFAM: gas vesicle synthesis protein GvpL/GvpF YP_004370818.1 COGs: COG0464 ATPase of the AAA+ class; InterProIPR003338:IPR004201:IPR003959:IPR003593:IPR 005938; KEGG: pin:Ping_1247 cell division protein CDC48; PFAM: ATPase, AAA-type, core; ATPase, AAA-type, VAT, N-terminal; Cell division protein 48, CDC48, domain 2; PRIAM: adenosinetriphosphatase; SMART: ATPase, AAA+ type, core; SPTR: Cell division cycle protein 48 homolog AF_1297; TIGRFAM: ATPase, AAA-type, CDC48; PFAM: ATPase associated with various cellular activities (AAA); Cell division protein 48 (CDC48), N-terminal domain; Cell division protein 48 (CDC48), domain 2; TIGRFAM: ATPase AAA YP_004370819.1 InterPro IPR002068; KEGG: pin:Ping_1246 heat shock protein, HSP20 family protein; PFAM: Heat shock protein Hsp20; SPTR: Heat shock protein, HSP20 family protein; PFAM: GvpH YP_004370820.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR002078:IPR002197:IPR003593; KEGG: pin:Ping_1245 two component, sigma54 specific, transcriptional regulator, fis family protein; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004370821.1 KEGG: gur:Gura_2843 hypothetical protein; SPTR: uncharacterized protein YP_004370822.1 COGs: COG2230 cyclopropane fatty acid synthase and related methyltransferase; InterPro IPR003333; KEGG: lpn:lpg1131 cyclopropane fatty acyl phospholipid synthase; PFAM: cyclopropane-fatty-acyl-phospholipid/mycolic acid synthase; PRIAM: cyclopropane-fatty-acyl-phospholipid synthase; SPTR: cyclopropane fatty acid synthase; PFAM: cyclopropane-fatty-acyl-phospholipid synthase YP_004370823.1 COGs: COG3497 Phage tail sheath protein FI; InterPro IPR007067; KEGG: ppd:Ppro_1827 phage tail sheath protein; SPTR: Phage tail sheath protein; PFAM: Phage tail sheath protein YP_004370824.1 InterPro IPR011747; KEGG: nde:NIDE2220 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP02241, phage tail region protein; PFAM: T4-like virus tail tube protein gp19; TIGRFAM: conserved hypothetical phage tail region protein YP_004370825.1 KEGG: ppd:Ppro_1825 hypothetical protein; SPTR: uncharacterized protein YP_004370826.1 KEGG: ssc:100152819 similar to Titin (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14); SPTR: uncharacterized protein YP_004370827.1 KEGG: ppd:Ppro_1823 hypothetical protein; SPTR: uncharacterized protein YP_004370828.1 COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003959:IPR003593; KEGG: ppd:Ppro_1822 ATPase central domain-containing protein; PFAM: ATPase, AAA-type, core; SPTR: AAA ATPase, central domain protein; PFAM: ATPase associated with various cellular activities (AAA) YP_004370829.1 KEGG: rxy:Rxyl_0906 HxlR family transcriptional regulator YP_004370830.1 KEGG: ppd:Ppro_1821 hypothetical protein; SPTR: uncharacterized protein YP_004370831.1 KEGG: ppd:Ppro_1820 hypothetical protein; SPTR: uncharacterized protein YP_004370832.1 KEGG: ppd:Ppro_1819 hypothetical protein; SPTR: uncharacterized protein YP_004370833.1 KEGG: ppd:Ppro_1818 hypothetical protein; SPTR: uncharacterized protein; PFAM: Phage late control gene D protein (GPD) YP_004370834.1 KEGG: chl:Chy400_2338 hypothetical protein; SPTR: uncharacterized protein; PFAM: Phage-related baseplate assembly protein YP_004370835.1 KEGG: ppd:Ppro_1816 hypothetical protein; SPTR: uncharacterized protein YP_004370836.1 COGs: COG3628 Phage baseplate assembly protein W; InterPro IPR007048; KEGG: ppd:Ppro_1815 hypothetical protein; PFAM: GPW/gp25; SPTR: uncharacterized protein; PFAM: Gene 25-like lysozyme YP_004370837.1 InterPro IPR011749; KEGG: ppd:Ppro_1814 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP02243; TIGRFAM: conserved hypothetical protein, phage tail-like region YP_004370838.1 KEGG: ppd:Ppro_1813 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: conserved hypothetical protein, phage tail-like region YP_004370839.1 KEGG: ppd:Ppro_1812 hypothetical protein; SPTR: uncharacterized protein YP_004370840.1 InterPro IPR006626; KEGG: ppd:Ppro_1811 hypothetical protein; SPTR: uncharacterized protein YP_004370841.1 InterPro IPR001534; KEGG: dat:HRM2_34790 hypothetical protein; PFAM: transthyretin-like; SPTR: uncharacterized protein; PFAM: transthyretin-like family YP_004370842.1 KEGG: amc:MADE_03048 SmpA/OmlA family lipoprotein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3192) YP_004370843.1 COGs: COG0820 Fe-S-cluster redox enzyme; HAMAP: ribosomal RNA large subunit methyltransferase RlmN; InterPro IPR004383:IPR007197; KEGG: gsu:GSU1111 ribosomal RNA large subunit methyltransferase N; PFAM: Radical SAM; SPTR: ribosomal RNA large subunit methyltransferase N; TIGRFAM: ribosomal RNA large subunit methyltransferase RlmN; PFAM: Radical SAM superfamily; TIGRFAM: 23S rRNA m2A2503 methyltransferase YP_004370844.1 COGs: COG1734 DnaK suppressor protein; InterPro IPR000962:IPR012784; KEGG: sfu:Sfum_2611 TraR/DksA family transcriptional regulator; SPTR: TraR/DksA family transcriptional regulator; TIGRFAM: RNA polymerase-binding, DksA; PFAM: Prokaryotic dksA/traR C4-type zinc finger; TIGRFAM: RNA polymerase-binding protein DksA YP_004370845.1 COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820:IPR023045; KEGG: mlo:mlr0616 molybdenum cofactor biosynthesis protein MoaC; PFAM: Molybdopterin cofactor biosynthesis C (MoaC) domain; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: Molybdenum cofactor biosynthesis C; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC YP_004370846.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; HAMAP: Chaperone DnaJ; InterPro IPR012724:IPR001623:IPR001305:IPR002939; KEGG: drt:Dret_1082 chaperone protein DnaJ; PFAM: Heat shock protein DnaJ, N-terminal; Heat shock protein DnaJ, cysteine-rich domain; Chaperone DnaJ, C-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Chaperone protein dnaJ; PFAM: DnaJ central domain (4 repeats); DnaJ C terminal region; DnaJ domain YP_004370847.1 KEGG: sat:SYN_01905 cytoplasmic protein; SPTR: Hypothetical cytosolic protein YP_004370848.1 COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013767:IPR013655:IPR013656:IPR003661:IPR 003594:IPR001789:IPR000014:IPR001610; KEGG: ppd:Ppro_2908 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; PAS fold; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; PAC motif; PAS; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SPTR: Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004370849.1 COGs: COG2189 adenine specific DNA methylase Mod; InterPro IPR002941; KEGG: dau:Daud_0708 DNA methylase N-4/N-6 domain-containing protein; PFAM: DNA methylase N-4/N-6; SPTR: DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase YP_004370850.1 COGs: COG0674 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: sfu:Sfum_1166 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; PRIAM: 2-oxoglutarate synthase; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: domain YP_004370851.1 InterPro IPR001450; KEGG: sfu:Sfum_1165 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain YP_004370852.1 COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR000991:IPR006221; KEGG: pjd:Pjdr2_0076 glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: glutamine amidotransferase of anthranilate synthase; TIGRFAM: Anthranilate synthase, glutamine amidotransferase domain; PFAM: glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase YP_004370853.1 COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805:IPR015890:IPR005256; KEGG: gsu:GSU2383 anthranilate synthase component I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase component I; TIGRFAM: Anthranilate synthase component I, PabB-like; PFAM: chorismate binding enzyme; Anthranilate synthase component I, N terminal region; TIGRFAM: anthranilate synthase component I, non-proteobacterial lineages YP_004370854.1 COGs: COG3640 CO dehydrogenase maturation factor; InterPro IPR002586; KEGG: sfu:Sfum_4099 cobyrinic acid a,c-diamide synthase; PFAM: cobyrinic acid a,c-diamide synthase; SPTR: cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004370855.1 InterPro IPR001387; KEGG: drt:Dret_1891 XRE family transcriptional regulator; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: XRE family transcriptional regulator; PFAM: Helix-turn-helix YP_004370856.1 COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR006683:IPR003736; KEGG: dol:Dole_1498 thioesterase superfamily protein; PFAM: Thioesterase superfamily; SPTR: Thioesterase superfamily protein; TIGRFAM: Phenylacetic acid degradation-related protein; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1 YP_004370857.1 COGs: COG1619 conserved hypothetical protein; InterPro IPR003507; KEGG: dal:Dalk_3806 peptidase U61 LD-carboxypeptidase A; PFAM: peptidase S66, LD-carboxypeptidase A; SPTR: LD-carboxypeptidase; PFAM: LD-carboxypeptidase YP_004370858.1 KEGG: ter:Tery_2637 hypothetical protein; SPTR: uncharacterized protein YP_004370859.1 COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: gsu:GSU2816 sensory box histidine kinase/response regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain YP_004370860.1 COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: glo:Glov_1910 phenylacetate--CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Phenylacetate--CoA ligase; SPTR: Phenylacetate--CoA ligase; PFAM: AMP-binding enzyme YP_004370861.1 COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: rpf:Rpic12D_3909 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004370862.1 COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: sfu:Sfum_4073 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter YP_004370863.1 COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: drt:Dret_1135 inner-membrane translocator; PFAM: ABC transporter permease; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component YP_004370864.1 COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: drt:Dret_1136 inner-membrane translocator; PFAM: ABC transporter permease; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component YP_004370865.1 KEGG: dbr:Deba_0921 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3124) YP_004370866.1 COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase; InterPro IPR000760; KEGG: gbm:Gbem_1510 inositol-1-monophosphatase; PFAM: Inositol monophosphatase; PRIAM: Inositol-phosphate phosphatase; SPTR: Inositol-1-monophosphatase; PFAM: Inositol monophosphatase YP_004370867.1 COGs: COG0705 membrane protein; InterPro IPR022764; KEGG: dsh:Dshi_1200 rhomboid family protein; PFAM: peptidase S54, rhomboid domain; SPTR: Rhomboid family protein; PFAM: Rhomboid family YP_004370868.1 COGs: COG1578 conserved hypothetical protein; InterPro IPR002791; KEGG: adg:Adeg_0546 protein of unknown function DUF89; PFAM: Domain of unknown function DUF89; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF89 YP_004370869.1 KEGG: pca:Pcar_1974 hypothetical protein; SPTR: uncharacterized protein YP_004370870.1 KEGG: cyh:Cyan8802_3400 signal transduction protein with NACHT domain; SPTR: signal transduction protein with Nacht domain YP_004370871.1 KEGG: hmo:HM1_2996 ATP-dependent deoxyribonuclease subunit A; SPTR: uncharacterized protein YP_004370872.1 KEGG: ang:An01g12500 hypothetical protein; SPTR: Catalytic activity: A monocarboxylic acid amide + H(2)O = a monocarboxylate + NH(3). YP_004370873.1 COGs: COG1219 ATP-dependent protease Clp ATPase subunit; InterPro IPR013093:IPR003593; KEGG: min:Minf_1842 ATP-dependent protease Clp, ATPase subunit; PFAM: ATPase, AAA-2; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent protease Clp, ATPase subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX) YP_004370874.1 KEGG: rlg:Rleg_4515 glutamine amidotransferase class-I; SPTR: glutamine amidotransferase class-I YP_004370875.1 COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594; KEGG: ccs:CCNA_03842 molybdopterin biosynthesis MoeB protein; PFAM: UBA/THIF-type NAD/FAD binding fold; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: ThiF family YP_004370877.1 KEGG: gur:Gura_1272 MetA-pathway phenol degradation-like protein; SPTR: protein involved in meta-pathway of phenol degradation-like protein YP_004370878.1 COGs: COG0462 phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946; KEGG: sfu:Sfum_1208 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: ribose-phosphate diphosphokinase; SPTR: ribose-phosphate pyrophosphokinase 1; TIGRFAM: phosphoribosyl pyrophosphokinase; PFAM: phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase YP_004370879.1 COGs: COG4222 conserved hypothetical protein; KEGG: npu:Npun_R1137 hypothetical protein; SPTR: uncharacterized protein YP_004370880.1 InterPro IPR011576; KEGG: app:CAP2UW1_1390 pyridoxamine 5'-phosphate oxidase-related FMN-binding; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; SPTR: Pyridoxamine 5'-phosphate oxidase-related FMN-binding; PFAM: Pyridoxamine 5'-phosphate oxidase YP_004370881.1 COGs: COG0047 phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain; HAMAP: phosphoribosylformylglycinamidine synthase I; InterPro IPR010075; KEGG: sfu:Sfum_0433 phosphoribosylformylglycinamidine synthase I; PRIAM: phosphoribosylformylglycinamidine synthase; SPTR: phosphoribosylformylglycinamidine synthase subunit I; TIGRFAM: phosphoribosylformylglycinamidine synthase I; TIGRFAM: phosphoribosylformylglycinamidine synthase I YP_004370882.1 COGs: COG0342 Preprotein translocase subunit SecD; InterProIPR005791:IPR022645:IPR005665:IPR022646:IPR 022813; KEGG: dak:DaAHT2_0637 protein-export membrane protein SecD; PFAM: Preprotein translocase, SecD/SecF/SecDF; SecD/SecF/SecDF export membrane protein, GG motif, N-terminal; SPTR: SecF protein:SecD export membrane protein; TIGRFAM: SecD export membrane protein; SecD/SecF/SecDF export membrane protein, bacteria; SecF protein; PFAM: protein export membrane protein; SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF YP_004370883.1 InterPro IPR004843; KEGG: sat:SYN_00526 calcineurin-like phosphoesterase; PFAM: Metallo-dependent phosphatase; SPTR: Calcineurin-like phosphoesterase; PFAM: Calcineurin-like phosphoesterase YP_004370884.1 COGs: COG1313 Uncharacterized Fe-S protein PflX homolog of pyruvate formate lyase activating protein; InterPro IPR007197; KEGG: sfu:Sfum_1696 radical SAM domain-containing protein; PFAM: Radical SAM; SPTR: radical SAM protein YP_004370885.1 KEGG: apo:Arcpr_0569 hypothetical protein; SPTR: uncharacterized protein YP_004370886.1 COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: nde:NIDE1291 ATP-dependent DNA helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: ATP-dependent DNA helicase; PFAM: UvrD/REP helicase YP_004370887.1 COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366:IPR000878:IPR003754; KEGG: dol:Dole_3062 uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole methylase; Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; PRIAM: Uroporphyrinogen-III C-methyltransferase., Uroporphyrinogen-III synthase; SPTR: Uroporphyrinogen-III C-methyltransferase; TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase YP_004370888.1 COGs: COG1636 conserved hypothetical protein; InterPro IPR003828; KEGG: sat:SYN_02970 cytoplasmic protein; PFAM: protein of unknown function DUF208; SPTR: Hypothetical cytosolic protein; PFAM: Uncharacterized BCR, COG1636 YP_004370889.1 COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR005810:IPR003781:IPR005811; KEGG: dol:Dole_0073 succinyl-CoA synthetase, alpha subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; CoA-binding; PRIAM: Succinate--CoA ligase (ADP-forming); SMART: CoA-binding; SPTR: Succinyl-CoA ligase [ADP-forming] subunit alpha; TIGRFAM: Succinyl-CoA ligase, alpha subunit; PFAM: CoA binding domain; CoA-ligase; TIGRFAM: succinyl-CoA synthetase, alpha subunit YP_004370890.1 COGs: COG0045 Succinyl-CoA synthetase beta subunit; HAMAP: Succinyl-CoA synthetase, beta subunit; InterPro IPR005809:IPR013650:IPR005811; KEGG: sus:Acid_3378 succinyl-CoA synthetase subunit beta; PFAM: ATP-grasp fold, succinyl-CoA synthetase-type; ATP-citrate lyase/succinyl-CoA ligase; PRIAM: Succinate--CoA ligase (ADP-forming); SPTR: Succinyl-CoA ligase [ADP-forming] subunit beta; TIGRFAM: Succinyl-CoA synthetase, beta subunit; PFAM: CoA-ligase; ATP-grasp domain; TIGRFAM: succinyl-CoA synthetase, beta subunit YP_004370891.1 KEGG: tad:TRIADDRAFT_56684 hypothetical protein; SPTR: uncharacterized protein YP_004370892.1 KEGG: pca:Pcar_1926 lipoprotein; SPTR: Lipoprotein YP_004370893.1 InterPro IPR013630:IPR013217:IPR013691; KEGG: msv:Mesil_2947 C-methyltransferase; PFAM: methyltransferase hyptothetical; methyltransferase type 12; C-methyltransferase; SPTR: methyltransferase; PFAM: C-methyltransferase; methyltransferase domain; Hypothetical methyltransferase YP_004370894.1 COGs: COG3510 cephalosporin hydroxylase; InterPro IPR007072; KEGG: mxa:MXAN_4416 cephalosporin hydroxylase; PFAM: Rhamnosyl O-methyltransferase/cephalosporin hydroxylase; SPTR: cephalosporin hydroxylase; PFAM: cephalosporin hydroxylase YP_004370895.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: tkm:TK90_0311 glycosyl transferase 2; PFAM: glycosyl transferase, family 2; SPTR: glycosyl transferase, family 2; PFAM: glycosyl transferase 2 YP_004370896.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: dsa:Desal_3630 polysaccharide biosynthesis protein CapD; PFAM: polysaccharide biosynthesis protein CapD-like; SPTR: polysaccharide biosynthesis protein CapD; TIGRFAM: Pseudaminic acid biosynthesis, PseB; PFAM: polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase YP_004370897.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR020026:IPR000653; KEGG: rca:Rcas_0777 DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; PRIAM: glutamine--scyllo-inositol transaminase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; TIGRFAM: Pseudaminic acid biosynthesis, PseC; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase YP_004370898.1 COGs: COG2089 Sialic acid synthase; InterPro IPR013132:IPR013974; KEGG: mae:Maeo_0420 N-acetylneuraminate synthase; PFAM: N-acetylneuraminic acid synthase, N-terminal; SAF domain; PRIAM: N-acetylneuraminate synthase; SPTR: N-acetylneuraminate synthase; PFAM: SAF domain; NeuB family YP_004370899.1 COGs: COG1083 CMP-N-acetylneuraminic acid synthetase; InterPro IPR003329; KEGG: mae:Maeo_0417 acylneuraminate cytidylyltransferase; PFAM: acylneuraminate cytidylyltransferase; PRIAM: N-acylneuraminate cytidylyltransferase; SPTR: acylneuraminate cytidylyltransferase; PFAM: Cytidylyltransferase YP_004370900.1 COGs: COG3980 Spore coat polysaccharide biosynthesis protein predicted glycosyltransferase; InterPro IPR020023:IPR007235:IPR000182; KEGG: rca:Rcas_0775 GCN5-like N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; glycosyl transferase, family 28, C-terminal; SPTR: GCN5-related N-acetyltransferase; TIGRFAM: Pseudaminic acid biosynthesis-associated protein PseG; PFAM: Acetyltransferase (GNAT) family; glycosyltransferase 28 C-terminal domain; TIGRFAM: pseudaminic acid biosynthesis-associated protein PseG YP_004370901.1 COGs: COG2089 Sialic acid synthase; InterPro IPR020030:IPR013132:IPR013974; KEGG: dau:Daud_1772 N-acetylneuraminate synthase; PFAM: N-acetylneuraminic acid synthase, N-terminal; SAF domain; PRIAM: N-acetylneuraminate synthase; SMART: SAF domain; SPTR: N-acetylneuraminate synthase; TIGRFAM: Pseudaminic acid biosynthesis, PseI; PFAM: SAF domain; NeuB family; TIGRFAM: pseudaminic acid synthase YP_004370902.1 COGs: COG0118 glutamine amidotransferase; HAMAP: Imidazole glycerol phosphate synthase, subunit H; InterPro IPR010139:IPR000991; KEGG: dal:Dalk_0634 imidazole glycerol phosphate synthase subunit HisH; PFAM: glutamine amidotransferase class-I, C-terminal; SPTR: Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; TIGRFAM: Imidazole glycerol phosphate synthase, subunit H; PFAM: glutamine amidotransferase class-I; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit YP_004370903.1 COGs: COG0107 Imidazoleglycerol-phosphate synthase; InterPro IPR006062; KEGG: dhd:Dhaf_1497 imidazole glycerol phosphate synthase subunit HisF; PFAM: histidine biosynthesis; SPTR: Imidazole glycerol phosphate synthase subunit hisF; PFAM: histidine biosynthesis protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit YP_004370904.1 InterPro IPR020022; KEGG: phe:Phep_3933 LPS biosynthesis protein; SPTR: Putitive LPS biosynthesis protein; TIGRFAM: N-acetyl sugar amidotransferase; TIGRFAM: N-acetyl sugar amidotransferase YP_004370905.1 InterPro IPR020027:IPR013216; KEGG: cak:Caul_4739 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; TIGRFAM: Pseudaminic acid biosynthesis-associated methyltransferase; PFAM: methyltransferase domain; TIGRFAM: pseudaminic acid biosynthesis-associated methylase YP_004370906.1 KEGG: mgm:Mmc1_2417 hypothetical protein; SPTR: uncharacterized protein YP_004370907.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: mgm:Mmc1_2416 glycosyl transferase, group 1; PFAM: glycosyl transferase, group 1; SPTR: glycosyl transferase, group 1; PFAM: glycosyl transferases group 1 YP_004370908.1 COGs: COG2192 carbamoyl transferase NodU family; InterPro IPR003696; KEGG: pau:PA14_37745 carbamoyl transferase; PFAM: Carbamoyltransferase; SPTR: Carbamoyltransferase; PFAM: Carbamoyltransferase YP_004370909.1 InterPro IPR010743; KEGG: tin:Tint_0198 methionine biosynthesis protein MetW; PFAM: methionine biosynthesis MetW; SPTR: methionine biosynthesis protein MetW; PFAM: methionine biosynthesis protein MetW YP_004370910.1 COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR011916:IPR002201; KEGG: tye:THEYE_A1548 lipopolysaccharide heptosyltransferase III, PFAM: glycosyl transferase, family 9; SPTR: Lipopolysaccharide heptosyltransferase III, ; TIGRFAM: Lipopolysaccharide heptosyltransferase III, PFAM: glycosyltransferase 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase III YP_004370911.1 COGs: COG1692 conserved hypothetical protein; InterPro IPR005235:IPR004843; KEGG: gsu:GSU1138 Ser/Thr protein phosphatase; PFAM: Metallo-dependent phosphatase; SPTR: Ser/Thr protein phosphatase; TIGRFAM: Conserved hypothetical protein CHP00282; manually curated; TIGRFAM: metallophosphoesterase, MG_246/BB_0505 family YP_004370912.1 COGs: COG1418 HD superfamily hydrolase; HAMAP: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; InterProIPR017705:IPR006675:IPR018111:IPR006674:IPR 004087:IPR003607; KEGG: sfu:Sfum_2578 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; K Homology, type 1, subgroup; SMART: Metal-dependent phosphohydrolase, HD domain; K Homology; SPTR: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; TIGRFAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Uncharacterised protein family HDIG; PFAM: KH domain; HD domain; Domain of unknown function (DUF3552); TIGRFAM: conserved hypothetical protein YmdA/YtgF; uncharacterized domain HDIG YP_004370913.1 KEGG: dbr:Deba_0293 cytoplasmic protein; SPTR: cytoplasmic protein YP_004370914.1 InterPro IPR007167; KEGG: dsa:Desal_2172 FeoA family protein; PFAM: Ferrous iron transporter, FeoA subunit; SMART: Ferrous iron transporter, FeoA subunit; SPTR: transcriptional regulator, Fur family; PFAM: FeoA domain YP_004370915.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: mxa:MXAN_3702 FUR family transcriptional regulator; PFAM: Ferric-uptake regulator; SPTR: Similar to ferric uptake regulation protein; PFAM: Ferric uptake regulator family YP_004370916.1 COGs: COG0334 glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006097:IPR006096; KEGG: gur:Gura_2895 Glu/Leu/Phe/Val dehydrogenase, C terminal; PFAM: glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain; PRIAM: glutamate dehydrogenase (NAD(P)(+)); SMART: glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; SPTR: glutamate dehydrogenase (NAD(P)+); PFAM: glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain YP_004370917.1 KEGG: sat:SYN_02507 outer membrane protein; SPTR: Outer membrane protein YP_004370918.1 COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR003715:IPR019554; KEGG: aco:Amico_1713 polysaccharide export protein; PFAM: polysaccharide export protein; Soluble ligand binding domain; SPTR: polysaccharide export protein; PFAM: SLBB-domain like (DUF1017); polysaccharide biosynthesis/export protein; SLBB domain YP_004370919.1 KEGG: msm:MSMEG_5522 TetR family transcriptional regulator protein; SPTR: uncharacterized protein YP_004370920.1 COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344:IPR000424; KEGG: ppd:Ppro_0449 single-strand binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; TIGRFAM: Single-strand DNA-binding; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb) YP_004370921.1 KEGG: dae:Dtox_3322 hypothetical protein; SPTR: uncharacterized protein YP_004370923.1 COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: dak:DaAHT2_2303 protein of unknown function DUF152; PFAM: Multi-copper polyphenol oxidoreductase, laccase; SPTR: uncharacterized protein; TIGRFAM: Multi-copper polyphenol oxidoreductase, laccase; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family YP_004370924.1 KEGG: gur:Gura_3032 hypothetical protein; SPTR: OmpA family protein YP_004370925.1 COGs: COG0796 glutamate racemase; HAMAP: glutamate racemase; InterPro IPR004391:IPR015942; KEGG: cpi:Cpin_6531 glutamate racemase; PFAM: Asp/Glu/hydantoin racemase; PRIAM: glutamate racemase; SPTR: glutamate racemase; TIGRFAM: glutamate racemase; PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: glutamate racemase YP_004370926.1 InterPro IPR013525; KEGG: mtp:Mthe_0378 ABC transporter; PFAM: ABC transporter; SPTR: ABC transporter; PFAM: ABC transporter YP_004370927.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: mtp:Mthe_0377 ABC transporter related; PFAM: ABC transporter-like; PRIAM: polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter YP_004370928.1 COGs: COG1808 membrane protein; InterPro IPR005240; KEGG: dsa:Desal_3149 hypothetical protein; PFAM: protein of unknown function DUF389; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF389); TIGRFAM: uncharacterized hydrophobic domain; TIGR00341 family protein YP_004370929.1 InterPro IPR013247:IPR003646; KEGG: pth:PTH_0786 hypothetical protein; PFAM: SH3, type 3; SMART: SH3-like domain, bacterial; SPTR: uncharacterized protein; PFAM: Bacterial SH3 domain YP_004370930.1 COGs: COG2255 Holliday junction resolvasome helicase subunit; HAMAP: DNA helicase, Holliday junction RuvB type; InterProIPR004605:IPR008824:IPR003959:IPR008823:IPR 003593; KEGG: dak:DaAHT2_1206 Holliday junction DNA helicase RuvB; PFAM: DNA helicase, Holliday junction RuvB type, C-terminal; ATPase, AAA-type, core; DNA helicase, Holliday junction RuvB type, N-terminal; SMART: ATPase, AAA+ type, core; SPTR: Holliday junction ATP-dependent DNA helicase ruvB; TIGRFAM: DNA helicase, Holliday junction RuvB type; PFAM: Holliday junction DNA helicase ruvB C-terminus; Holliday junction DNA helicase ruvB N-terminus; TIGRFAM: Holliday junction DNA helicase, RuvB subunit YP_004370931.1 KEGG: rpc:RPC_2516 hypothetical protein; SPTR: uncharacterized protein YP_004370932.1 COGs: COG2715 Uncharacterized membrane protein required for spore maturation in B.subtilis.; InterPro IPR011642; KEGG: sat:SYN_01085 spore maturation protein A; PFAM: nucleoside recognition; SPTR: Spore maturation protein A; PFAM: nucleoside recognition YP_004370933.1 COGs: COG0700 membrane protein; InterPro IPR011642; KEGG: gem:GM21_3987 spore maturation protein B; PFAM: nucleoside recognition; SPTR: Spore maturation protein B; PFAM: nucleoside recognition YP_004370934.1 KEGG: bpy:Bphyt_7224 hypothetical protein; SPTR: uncharacterized protein YP_004370935.1 COGs: COG0234 Co-chaperonin GroES (HSP10); HAMAP: Chaperonin Cpn10; InterPro IPR020818; KEGG: drt:Dret_2175 chaperonin Cpn10; PFAM: Chaperonin Cpn10; SMART: Chaperonin Cpn10; SPTR: 10 kDa chaperonin; PFAM: Chaperonin 10 Kd subunit YP_004370936.1 COGs: COG0459 Chaperonin GroEL (HSP60 family); HAMAP: Chaperonin Cpn60; InterPro IPR001844:IPR002423; KEGG: sat:SYN_03223 chaperonin GroEL; PFAM: Chaperonin Cpn60/TCP-1; SPTR: 60 kDa chaperonin 2; TIGRFAM: Chaperonin Cpn60; PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: chaperonin GroL YP_004370937.1 COGs: COG0069 glutamate synthase domain 2; InterPro IPR002932; KEGG: drm:Dred_2809 glutamate synthase-like protein; PFAM: glutamate synthase, central-C; SPTR: glutamate synthase-like protein; PFAM: Conserved region in glutamate synthase YP_004370938.1 COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: vei:Veis_1408 DNA polymerase beta subunit; PFAM: nucleotidyl transferase domain; SPTR: uncharacterized protein ofn34; PFAM: nucleotidyltransferase domain YP_004370939.1 InterPro IPR008201; KEGG: vei:Veis_1407 hypothetical protein; PFAM: protein of unknown function DUF86; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF86 YP_004370940.1 InterPro IPR013216; KEGG: nhl:Nhal_2307 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; PFAM: cyclopropane-fatty-acyl-phospholipid synthase YP_004370942.1 InterPro IPR013498; KEGG: gur:Gura_2103 DNA topoisomerase type IA Zn finger domain-containing protein; PFAM: DNA topoisomerase, type IA, zn finger; SPTR: Topoisomerase; PFAM: Topoisomerase DNA binding C4 zinc finger YP_004370943.1 KEGG: rrs:RoseRS_3671 hypothetical protein; SPTR: uncharacterized protein YP_004370944.1 InterPro IPR002059:IPR001440:IPR019734; KEGG: rrs:RoseRS_3670 cold-shock protein, DNA-binding; PFAM: Cold-shock protein, DNA-binding; Tetratricopeptide TPR-1; SPTR: Cold-shock protein, DNA-binding; PFAM: 'Cold-shock' DNA-binding domain YP_004370945.1 KEGG: amt:Amet_1499 transposase, IS4 family protein; SPTR: transposase, IS4 family protein; PFAM: transposase domain (DUF772) YP_004370946.1 KEGG: pbe:PB001621.02.0 hypothetical protein; SPTR: uncharacterized protein YP_004370947.1 KEGG: sat:SYN_02742 cytoplasmic protein; SPTR: Hypothetical cytosolic protein YP_004370948.1 COGs: COG2378 transcriptional regulator protein; KEGG: gur:Gura_0944 helix-turn-helix, type 11 domain-containing protein; SPTR: Helix-turn-helix, type 11 domain protein YP_004370949.1 COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: sfu:Sfum_0002 histone family protein DNA-binding protein; PFAM: histone-like bacterial DNA-binding protein; SMART: histone-like bacterial DNA-binding protein; SPTR: histone family protein DNA-binding protein; PFAM: Bacterial DNA-binding protein YP_004370950.1 COGs: COG2006 conserved hypothetical protein; InterPro IPR007160; KEGG: dma:DMR_13230 hypothetical protein; PFAM: Domain of unknown function DUF362; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF362) YP_004370951.1 KEGG: dma:DMR_13220 hypothetical protein; SPTR: uncharacterized protein YP_004370952.1 InterPro IPR012495; KEGG: bph:Bphy_5858 TadE family protein; PFAM: TadE-like; SPTR: TadE family protein; PFAM: TadE-like protein YP_004370953.1 InterPro IPR018705; KEGG: pvi:Cvib_0567 hypothetical protein; PFAM: protein of unknown function DUF2134, membrane; SPTR: uncharacterized protein; PFAM: Predicted membrane protein (DUF2134) YP_004370954.1 COGs: COG4961 Flp pilus assembly protein TadG; InterPro IPR012495; KEGG: slp:Slip_1923 TadE family protein; PFAM: TadE-like; SPTR: TadE family protein; PFAM: TadE-like protein YP_004370955.1 KEGG: bgf:BC1003_2955 filamentous hemagglutinin family outer membrane protein; SPTR: Filamentous hemagglutinin family outer membrane protein YP_004370956.1 KEGG: dal:Dalk_2416 hypothetical protein; SPTR: uncharacterized protein YP_004370957.1 InterPro IPR013105:IPR001440:IPR019734; KEGG: drt:Dret_1158 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: TPR repeat-containing protein; PFAM: Tetratricopeptide repeat YP_004370958.1 COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR001440:IPR019734; KEGG: nhl:Nhal_1414 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide repeat YP_004370959.1 KEGG: sat:SYN_01493 hypothetical protein; SPTR: Hypothetical exported protein YP_004370960.1 COGs: COG4964 Flp pilus assembly protein secretin CpaC; InterPro IPR007055:IPR004846; KEGG: sfu:Sfum_1493 type II and III secretion system protein; PFAM: Type II/III secretion system; transport-associated; SPTR: Type II and III secretion system protein; PFAM: phospholipid-binding domain; Bacterial type II and III secretion system protein YP_004370961.1 InterPro IPR009923; KEGG: dbr:Deba_0333 protein of unknown function DUF1458; PFAM: Dodecin flavoprotein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1458) YP_004370962.1 COGs: COG0430 RNA 3'-terminal phosphate cyclase; HAMAP: RNA 3'-terminal phosphate cyclase predicted; InterPro IPR017770:IPR000228:IPR013796:IPR020723; KEGG: gur:Gura_1665 RNA-3'-phosphate cyclase; PFAM: RNA 3'-terminal phosphate cyclase-like; RNA 3'-terminal phosphate cyclase, insert domain; PRIAM: RNA-3'-phosphate cyclase; SPTR: RNA 3'-terminal phosphate cyclase (RNA-3'-phosphate cyclase) (RNA cyclase); TIGRFAM: RNA 3'-terminal phosphate cyclase, subgroup; PFAM: RNA 3'-terminal phosphate cyclase (RTC), insert domain; RNA 3'-terminal phosphate cyclase; TIGRFAM: RNA 3'-phosphate cyclase YP_004370963.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR000014:IPR003018:IPR013767:IPR003594:IPR 001789; KEGG: dal:Dalk_5108 PAS/PAC sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver domain; GAF; PAS fold; ATPase-like, ATP-binding domain; SMART: Signal transduction response regulator, receiver domain; GAF; PAS; SPTR: ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; TIGRFAM: PAS; PFAM: Response regulator receiver domain; GAF domain; PAS fold; TIGRFAM: PAS domain S-box YP_004370964.1 COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: ade:Adeh_2612 lipid A biosynthesis acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase; SPTR: Lipid A biosynthesis (KDO)2-(Lauroyl)-lipid IVA acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase YP_004370965.1 COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR017568:IPR014030:IPR014031:IPR020841; KEGG: tye:THEYE_A0103 beta-ketoacyl-acyl carrier protein synthase II; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase II; SMART: polyketide synthase, beta-ketoacyl synthase domain; SPTR: Beta-ketoacyl-acyl carrier protein synthase II; TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: beta-ketoacyl-acyl-carrier-protein synthase II YP_004370966.1 COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176:IPR006108; KEGG: pca:Pcar_0349 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; PRIAM: 3-hydroxyacyl-CoA dehydrogenase; SPTR: 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YP_004370967.1 COGs: COG2067 Long-chain fatty acid transport protein; InterPro IPR005017; KEGG: gem:GM21_2174 aromatic hydrocarbon degradation membrane protein; PFAM: Membrane protein, aromatic hydrocarbon degradation; SPTR: Membrane protein involved in aromatic hydrocarbon degradation; PFAM: Outer membrane protein transport protein (OMPP1/FadL/TodX) YP_004370968.1 COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: vpr:Vpar_0546 lipid A biosynthesis acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase; SPTR: Lipid A biosynthesis (KDO)2-(Lauroyl)-lipid IVA acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase YP_004370969.1 KEGG: pop:POPTR_780486 hypothetical protein YP_004370970.1 COGs: COG0591 Na+/proline symporter; InterPro IPR003018:IPR003661:IPR003594; KEGG: gur:Gura_2045 GAF sensor protein; PFAM: ATPase-like, ATP-binding domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SPTR: phytochrome sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Sodium:solute symporter family; GAF domain; His Kinase A (phosphoacceptor) domain YP_004370971.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR013767:IPR003661:IPR003594:IPR 003018:IPR001610; KEGG: mmh:Mmah_1394 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAS; PAC motif; SPTR: PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004370972.1 COGs: COG4448 L-asparaginase II; InterPro IPR010349; KEGG: dbr:Deba_3148 asparaginase; PFAM: L-asparaginase II; SPTR: Asparaginase; PFAM: L-asparaginase II YP_004370973.1 COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: sfu:Sfum_2126 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: histidine triad (HIT) protein; PFAM: HIT domain YP_004370974.1 KEGG: dbr:Deba_1299 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1049) YP_004370975.1 KEGG: tet:TTHERM_00059520 hypothetical protein; SPTR: polyprotein YP_004370976.1 COGs: COG4206 Outer membrane cobalamin receptor protein; InterPro IPR012910:IPR000531; KEGG: cts:Ctha_2210 TonB-dependent receptor plug; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; SPTR: TonB-dependent receptor plug; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain; TIGRFAM: TonB-dependent heme/hemoglobin receptor family protein YP_004370977.1 COGs: COG0249 Mismatch repair ATPase (MutS family); HAMAP: DNA mismatch repair protein MutS, type 1; InterProIPR005748:IPR007695:IPR007860:IPR007696:IPR 007861:IPR000432; KEGG: sfu:Sfum_0730 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, core; DNA mismatch repair protein MutS-like, N-terminal; DNA mismatch repair protein MutS, connector; DNA mismatch repair protein MutS, clamp; SMART: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, core; SPTR: DNA mismatch repair protein mutS; TIGRFAM: DNA mismatch repair protein MutS, type 1; PFAM: MutS family domain IV; MutS domain II; MutS domain V; MutS domain I; MutS domain III; TIGRFAM: DNA mismatch repair protein MutS YP_004370978.1 COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004805:IPR004013:IPR011708:IPR004365:IPR 003141; KEGG: dbr:Deba_2373 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: polymerase/histidinol phosphatase, N-terminal; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; TIGRFAM: DNA-directed DNA polymerase III (polc) YP_004370979.1 COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR016041; KEGG: dat:HRM2_16690 acetyl-CoA decarbonylase/synthase complex subunit delta; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; SPTR: CdhD; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase, delta subunit YP_004370980.1 COGs: COG1151 6Fe-6S prismane cluster-containing protein; InterPro IPR010047:IPR004137; KEGG: dbr:Deba_0241 carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane; PRIAM: Carbon-monoxide dehydrogenase (acceptor); SPTR: Carbon-monoxide dehydrogenase, catalytic subunit; TIGRFAM: Carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane/CO dehydrogenase; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit YP_004370981.1 COGs: COG1614 CO dehydrogenase/acetyl-CoA synthase beta subunit; InterPro IPR004461; KEGG: sfu:Sfum_2565 bifunctional acetyl-CoA decarbonylase/synthase complex subunit alpha/beta; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; PRIAM: CO-methylating acetyl-CoA synthase; SPTR: Acetyl-CoA decarbonylase/synthase alpha subunit / acetyl-CoA decarbonylase/synthase beta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; TIGRFAM: CO dehydrogenase/CO-methylating acetyl-CoA synthase complex, beta subunit YP_004370982.1 COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR007202:IPR016041; KEGG: dal:Dalk_0682 acetyl-CoA decarbonylase/synthase complex subunit gamma; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Fe-S cluster; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; PFAM: Fe-S cluster; CO dehydrogenase/acetyl-CoA synthase delta subunit YP_004370983.1 COGs: COG1410 methionine synthase I cobalamin-binding domain; InterPro IPR000489; KEGG: sfu:Sfum_2563 dihydropteroate synthase, DhpS; PFAM: Pterin-binding; SPTR: Pterin binding enzyme; PFAM: Pterin binding enzyme YP_004370984.1 COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005268:IPR005269; KEGG: mma:MM_3075 hypothetical protein; PFAM: Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00725; PFAM: Possible lysine decarboxylase; TIGRFAM: TIGR00725 family protein YP_004370985.1 KEGG: nde:NIDE4314 hypothetical protein; SPTR: uncharacterized protein YP_004370986.1 COGs: COG0279 phosphoheptose isomerase; HAMAP: phosphoheptose isomerase; InterPro IPR004515:IPR001347:IPR020620; KEGG: dvm:DvMF_0582 phosphoheptose isomerase; PFAM: Sugar isomerase (SIS); SPTR: phosphoheptose isomerase; TIGRFAM: phosphoheptose isomerase, subgroup; PFAM: SIS domain; TIGRFAM: phosphoheptose isomerase YP_004370987.1 COGs: COG0057 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR006424:IPR020828:IPR020829; KEGG: sfu:Sfum_2061 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SMART: glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; SPTR: glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I YP_004370988.1 COGs: COG0126 3-phosphoglycerate kinase; HAMAP: phosphoglycerate kinase; InterPro IPR001576; KEGG: gur:Gura_2060 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: phosphoglycerate kinase; SPTR: phosphoglycerate kinase; PFAM: phosphoglycerate kinase YP_004370989.1 COGs: COG0149 Triosephosphate isomerase; InterPro IPR000652; KEGG: glo:Glov_1618 triosephosphate isomerase; PFAM: Triosephosphate isomerase; PRIAM: Triose-phosphate isomerase; SPTR: Triosephosphate isomerase; TIGRFAM: Triosephosphate isomerase; PFAM: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase YP_004370990.1 COGs: COG1314 Preprotein translocase subunit SecG; InterPro IPR004692; KEGG: dol:Dole_0498 preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; SPTR: Preprotein translocase, SecG subunit; TIGRFAM: Preprotein translocase SecG subunit; PFAM: Preprotein translocase SecG subunit; TIGRFAM: protein translocase, SecG subunit YP_004370991.1 KEGG: cja:CJA_2655 probable ATPase; SPTR: uncharacterized protein YP_004370992.1 KEGG: esi:Exig_2235 tyrosyl-tRNA synthetase YP_004370993.1 KEGG: ecb:100146222 similar to Oral-facial-digital syndrome 1 protein (protein 71-7A); SPTR: Predicted protein YP_004370994.1 KEGG: aag:AaeL_AAEL012141 acetylcholinesterase; SPTR: uncharacterized protein YP_004370995.1 KEGG: ctp:CTRG_04372 hypothetical protein; SPTR: uncharacterized protein YP_004370996.1 KEGG: scl:sce5015 hypothetical protein; SPTR: uncharacterized protein YP_004370997.1 COGs: COG4737 conserved hypothetical protein; KEGG: sfu:Sfum_3429 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1044) YP_004370998.1 COGs: COG2944 transcriptional regulator protein; InterPro IPR001387; KEGG: sfu:Sfum_3428 XRE family transcriptional regulator; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: XRE family transcriptional regulator; PFAM: Helix-turn-helix YP_004370999.1 COGs: COG1866 phosphoenolpyruvate carboxykinase (ATP); HAMAP: phosphoenolpyruvate carboxykinase, ATP-utilising; InterPro IPR001272; KEGG: dal:Dalk_2228 phosphoenolpyruvate carboxykinase; PFAM: phosphoenolpyruvate carboxykinase, ATP-utilising; PRIAM: phosphoenolpyruvate carboxykinase (ATP); SPTR: phosphoenolpyruvate carboxykinase [ATP]; TIGRFAM: phosphoenolpyruvate carboxykinase, ATP-utilising; PFAM: phosphoenolpyruvate carboxykinase; TIGRFAM: phosphoenolpyruvate carboxykinase (ATP) YP_004371000.1 InterPro IPR000551; KEGG: ppd:Ppro_2301 MerR family transcriptional regulator; PFAM: HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: transcriptional regulator, MerR family; PFAM: MerR family regulatory protein YP_004371001.1 KEGG: ppp:PHYPADRAFT_165131 hypothetical protein; SPTR: Predicted protein YP_004371002.1 COGs: COG1620 L-lactate permease; InterPro IPR003804; KEGG: sfu:Sfum_2879 L-lactate permease-like; PFAM: L-lactate permease; SPTR: L-lactate permease-like; PFAM: L-lactate permease YP_004371003.1 KEGG: syd:Syncc9605_0335 hypothetical protein; SPTR: Uncharacterized signaling protein PA1727 YP_004371004.1 KEGG: pgu:PGUG_00921 hypothetical protein; SPTR: Trimethyllysine dioxygenase YP_004371005.1 COGs: COG1519 3-deoxy-D-manno-octulosonic-acid transferase; InterPro IPR007507; KEGG: gsu:GSU2259 3-deoxy-D-manno-octulosonic-acid transferase; PFAM: Three-deoxy-D-manno-octulosonic-acid transferase, N-terminal; SPTR: CMP-3-deoxy-D-manno-octulosonate--lipid A tetraacyldisaccharide 3-deoxy-D-manno-octulosonate transferase; PFAM: 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) YP_004371006.1 KEGG: dbr:Deba_1489 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2939) YP_004371007.1 COGs: COG1092 SAM-dependent methyltransferase; KEGG: mxa:MXAN_5568 hypothetical protein; SPTR: uncharacterized protein; PFAM: S-adenosylmethionine-dependent methyltransferase YP_004371008.1 COGs: COG2210 conserved hypothetical protein; KEGG: sfu:Sfum_0986 hypothetical protein; SPTR: uncharacterized protein; PFAM: DsrE/DsrF-like family YP_004371009.1 InterPro IPR001845; KEGG: afr:AFE_2369 ArsR family transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: ArsR family transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family YP_004371010.1 KEGG: drt:Dret_1786 hypothetical protein; SPTR: uncharacterized protein YP_004371011.1 COGs: COG0348 polyferredoxin; InterPro IPR001450; KEGG: dak:DaAHT2_2325 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_004371012.1 COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: dbr:Deba_1846 histone family protein DNA-binding protein; PFAM: histone-like bacterial DNA-binding protein; SMART: histone-like bacterial DNA-binding protein; SPTR: Integration host factor subunit alpha; PFAM: Bacterial DNA-binding protein YP_004371013.1 InterPro IPR013525; KEGG: nth:Nther_0987 ABC transporter; PFAM: ABC transporter; SPTR: ABC transporter; PFAM: ABC transporter YP_004371014.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: mem:Memar_0021 daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter-like; PRIAM: sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Daunorubicin resistance ABC transporter, ATP-binding protein; PFAM: ABC transporter YP_004371015.1 COGs: COG1180 pyruvate-formate lyase-activating enzyme; InterPro IPR006311:IPR007197:IPR006638; KEGG: sfu:Sfum_1995 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: radical SAM protein; PFAM: Radical SAM superfamily YP_004371016.1 COGs: COG0012 GTPase probable translation factor; InterPro IPR004396:IPR002917:IPR013029; KEGG: rmr:Rmar_0027 GTP-binding protein YchF; PFAM: Domain of unknown function DUF933; GTP-binding protein, HSR1-related; SPTR: GTP-binding protein YchF; TIGRFAM: Conserved hypothetical protein CHP00092; PFAM: GTPase of unknown function; protein of unknown function (DUF933); TIGRFAM: GTP-binding protein YchF YP_004371017.1 COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: glo:Glov_2936 competence protein F, PFAM: phosphoribosyltransferase; SPTR: Competence protein F, ; PFAM: phosphoribosyl transferase domain; TIGRFAM: comF family protein YP_004371018.1 COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterPro IPR011914:IPR004821:IPR004820; KEGG: glo:Glov_0977 RfaE bifunctional protein; PFAM: Cytidylyltransferase; SPTR: bifunctional protein hldE; TIGRFAM: RfaE bifunctional protein, domain II; Cytidyltransferase-related; PFAM: Cytidylyltransferase; TIGRFAM: rfaE bifunctional protein, domain II; cytidyltransferase-related domain YP_004371019.1 InterPro IPR001087; KEGG: mgm:Mmc1_2418 hypothetical protein; PFAM: Lipase, GDSL; SPTR: uncharacterized protein; PFAM: GDSL-like Lipase/acylhydrolase YP_004371020.1 COGs: COG1696 membrane protein involved in D-alanine export; InterPro IPR004299; KEGG: mgm:Mmc1_3042 membrane bound O-acyl transferase, MBOAT family protein; PFAM: Membrane bound O-acyl transferase, MBOAT; SPTR: Membrane bound O-acyl transferase, MBOAT family protein; PFAM: MBOAT family YP_004371021.1 COGs: COG0293 23S rRNA methylase; HAMAP: ribosomal RNA large subunit methyltransferase E; InterPro IPR002877:IPR015507; KEGG: bba:Bd1423 cell division protein FtsJ; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; SPTR: ribosomal RNA large subunit methyltransferase E; PFAM: FtsJ-like methyltransferase; TIGRFAM: cell division protein FtsJ YP_004371022.1 COGs: COG0217 conserved hypothetical protein; HAMAP: protein of unknown function DUF28; InterPro IPR002876; KEGG: sat:SYN_02974 hypothetical protein; PFAM: protein of unknown function DUF28; SPTR: UPF0082 protein SYNAS_07390; TIGRFAM: protein of unknown function DUF28; PFAM: Domain of unknown function DUF28; TIGRFAM: DNA-binding regulatory protein, YebC/PmpR family YP_004371023.1 COGs: COG0817 Holliday junction resolvasome endonuclease subunit; HAMAP: Crossover junction endodeoxyribonuclease RuvC; InterPro IPR002176; KEGG: gsu:GSU1075 Holliday junction resolvase; PFAM: Crossover junction endodeoxyribonuclease RuvC; PRIAM: Crossover junction endodeoxyribonuclease; SPTR: Crossover junction endodeoxyribonuclease ruvC; TIGRFAM: Crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC YP_004371024.1 COGs: COG0632 Holliday junction resolvasome DNA-binding subunit; HAMAP: Bacterial DNA recombination protein RuvA; InterPro IPR000085:IPR013849:IPR011114:IPR003583; KEGG: ppd:Ppro_2671 Holliday junction DNA helicase RuvA; PFAM: DNA helicase, Holliday junction RuvA type, domain I, bacterial; DNA helicase, Holliday junction RuvA type, domain III, C-terminal; SPTR: Holliday junction ATP-dependent DNA helicase ruvA; TIGRFAM: Bacterial DNA recombination protein RuvA; PFAM: RuvA, C-terminal domain; RuvA N terminal domain; TIGRFAM: Holliday junction DNA helicase, RuvA subunit YP_004371025.1 InterPro IPR005079; KEGG: axy:AXYL_03701 acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 4; PFAM: peptidase C45, acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; SPTR: acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; PFAM: acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase YP_004371026.1 KEGG: smm:Smp_148620 hypothetical protein; SPTR: Expressed protein YP_004371027.1 COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR004356:IPR000873; KEGG: sfu:Sfum_1683 phenylacetate--CoA ligase; PFAM: AMP-dependent synthetase/ligase; P pili regulatory PapB protein; PRIAM: Phenylacetate--CoA ligase; SPTR: Phenylacetate-CoA ligase; PFAM: AMP-binding enzyme; TIGRFAM: phenylacetate-CoA ligase YP_004371028.1 COGs: COG4747 ACT domain-containing protein; InterPro IPR002912; KEGG: sfu:Sfum_1682 amino acid-binding ACT domain-containing protein; PFAM: Amino acid-binding ACT; SPTR: ACT domain protein; PFAM: ACT domain YP_004371029.1 COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: sfu:Sfum_1681 extracellular ligand-binding receptor; PFAM: Extracellular ligand-binding receptor; SPTR: Extracellular ligand-binding receptor; PFAM: Receptor family ligand binding region YP_004371030.1 COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: gem:GM21_2039 inner-membrane translocator; PFAM: ABC transporter permease; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component YP_004371031.1 COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: sfu:Sfum_1679 inner-membrane translocator; PFAM: ABC transporter permease; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component YP_004371032.1 COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: dal:Dalk_1706 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004371033.1 COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: dal:Dalk_1705 ABC transporter related; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter YP_004371034.1 COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: ddf:DEFDS_0957 phenylacetate-CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: Phenylacetate--CoA ligase; SPTR: Phenylacetate-CoA ligase; PFAM: AMP-binding enzyme YP_004371035.1 COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: drt:Dret_1137 extracellular ligand-binding receptor; PFAM: Extracellular ligand-binding receptor; SPTR: Extracellular ligand-binding receptor; PFAM: Receptor family ligand binding region YP_004371036.1 KEGG: sfu:Sfum_1116 pyridoxamine 5'-phosphate oxidase-related, FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase-related, FMN-binding; manually curated; PFAM: Pyridoxamine 5'-phosphate oxidase YP_004371037.1 InterPro IPR008538; KEGG: mca:MCA1625 hypothetical protein; PFAM: Domain of unknown function DUF820; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF820) YP_004371038.1 COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: dak:DaAHT2_1915 peptidase M24; PFAM: peptidase M24, structural domain; Creatinase; SPTR: peptidase M24; PFAM: Metallopeptidase M24; Creatinase/Prolidase N-terminal domain YP_004371039.1 COGs: COG3635 phosphoglycerate mutase AP superfamily; InterPro IPR013371:IPR004456:IPR019304:IPR006124; KEGG: dbr:Deba_1383 proposed homoserine kinase; PFAM: Bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme; PRIAM: phosphoglycerate mutase; SPTR: Proposed homoserine kinase; TIGRFAM: Homoserine kinase, ; Cofactor-independent phosphoglycerate mutase, archaeal; PFAM: Metalloenzyme superfamily; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal form; proposed homoserine kinase YP_004371040.1 COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912; KEGG: sfu:Sfum_1218 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain YP_004371041.1 COGs: COG0436 aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: dal:Dalk_0710 aminotransferase class I and II; PFAM: Aminotransferase, class I/classII; PRIAM: LL-diaminopimelate aminotransferase; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II YP_004371042.1 KEGG: mhu:Mhun_1519 transposase IS66; SPTR: uncharacterized protein; PFAM: transposase IS66 family YP_004371043.1 COGs: COG3821 membrane protein; InterPro IPR006747; KEGG: dat:HRM2_39080 hypothetical protein; PFAM: protein of unknown function DUF599; SPTR: uncharacterized protein; PFAM: protein of unknown function, DUF599 YP_004371044.1 COGs: COG0373 glutamyl-tRNA reductase; HAMAP: Tetrapyrrole biosynthesis, glutamyl-tRNA reductase; InterPro IPR000343:IPR015895:IPR006151:IPR015896; KEGG: dat:HRM2_10870 HemA; PFAM: Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase; Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal; Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain; SPTR: glutamyl-tRNA reductase; TIGRFAM: Tetrapyrrole biosynthesis, glutamyl-tRNA reductase; PFAM: shikimate / quinate 5-dehydrogenase; glutamyl-tRNAGlu reductase, N-terminal domain; glutamyl-tRNAGlu reductase, dimerisation domain; TIGRFAM: glutamyl-tRNA reductase YP_004371045.1 COGs: COG4137 ABC transporter permease component; InterPro IPR002541; KEGG: pca:Pcar_3065 cytochrome c biogenesis protein; PFAM: Cytochrome c assembly protein; SPTR: Cytochrome c biogenesis protein; PFAM: Cytochrome C assembly protein; TIGRFAM: cytochrome c-type biogenesis protein CcsB YP_004371046.1 COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR006367; KEGG: dal:Dalk_3436 siroheme synthase; SPTR: Siroheme synthase; TIGRFAM: Sirohaem synthase, N-terminal; TIGRFAM: siroheme synthase, N-terminal domain YP_004371047.1 KEGG: tet:TTHERM_00191900 hypothetical protein YP_004371048.1 KEGG: afl:Aflv_1640 pyrophosphatase; SPTR: Predicted pyrophosphatase YP_004371049.1 KEGG: dbr:Deba_0961 hypothetical protein; SPTR: uncharacterized protein YP_004371050.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254; KEGG: pca:Pcar_2948 serine endoprotease; PFAM: peptidase S1/S6, chymotrypsin/Hap; SPTR: Serine endoprotease; PFAM: Trypsin YP_004371051.1 KEGG: xtr:100489328 low density lipoprotein receptor-related protein 6; SPTR: Chromosome undetermined SCAF7722, whole genome shotgun sequence. YP_004371052.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: kol:Kole_0405 alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, C-terminal; PRIAM: L-iditol 2-dehydrogenase; SPTR: Alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain YP_004371053.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: dbr:Deba_2087 glycosyl transferase group 1; PFAM: glycosyl transferase, group 1; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1 YP_004371054.1 InterPro IPR005358; KEGG: tye:THEYE_A0135 lipoprotein, PFAM: Uncharacterised protein family UPF0153; SPTR: Lipoprotein, ; PFAM: Uncharacterised protein family (UPF0153) YP_004371056.1 COGs: COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase; HAMAP: UDP-3-O-acyl N-acetylglucosamine deacetylase; InterPro IPR004463; KEGG: dbr:Deba_0664 UDP-3-0-acyl N-acetylglucosamine deacetylase; PFAM: UDP-3-O-acyl N-acetylglucosamine deacetylase; SPTR: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; TIGRFAM: UDP-3-O-acyl N-acetylglucosamine deacetylase; PFAM: UDP-3-O-acyl N-acetylglycosamine deacetylase; TIGRFAM: UDP-3-0-acyl N-acetylglucosamine deacetylase YP_004371057.1 COGs: COG0621 2-methylthioadenine synthetase; InterProIPR005839:IPR006467:IPR013848:IPR007197:IPR 006638; KEGG: sfu:Sfum_0166 RNA modification protein; PFAM: methylthiotransferase, N-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: RNA modification enzyme, MiaB family; TIGRFAM: MiaB-like tRNA modifying enzyme; methylthiotransferase; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme; radical SAM methylthiotransferase, MiaB/RimO family YP_004371058.1 COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; HAMAP: tRNA-specific 2-thiouridylase; InterPro IPR004506; KEGG: gme:Gmet_0873 tRNA-specific 2-thiouridylase MnmA; PFAM: tRNA-specific 2-thiouridylase; SPTR: tRNA-specific 2-thiouridylase mnmA; TIGRFAM: tRNA-specific 2-thiouridylase; manually curated; PFAM: tRNA methyl transferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase YP_004371059.1 InterPro IPR009875; KEGG: sus:Acid_0768 type IV pilus assembly PilZ; PFAM: Type IV pilus assembly PilZ; SPTR: filamentous hemagglutinin family protein; PFAM: PilZ domain YP_004371060.1 COGs: COG1151 6Fe-6S prismane cluster-containing protein; InterPro IPR010047:IPR004137; KEGG: dbr:Deba_0241 carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane; PRIAM: Carbon-monoxide dehydrogenase (acceptor); SPTR: Carbon-monoxide dehydrogenase, catalytic subunit; TIGRFAM: Carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane/CO dehydrogenase; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit YP_004371061.1 COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: svi:Svir_26230 hypothetical protein; PFAM: Sulphatase-modifying factor; SPTR: uncharacterized protein; PFAM: formylglycine-generating sulfatase enzyme YP_004371062.1 COGs: COG1452 Organic solvent tolerance protein OstA; InterPro IPR007543; KEGG: dat:HRM2_26760 OstA; PFAM: Organic solvent tolerance protein, C-terminal; SPTR: uncharacterized protein; PFAM: Organic solvent tolerance protein YP_004371063.1 COGs: COG1719 hydrocarbon binding protein (contains V4R domain); InterPro IPR004096; KEGG: gur:Gura_0328 4-vinyl reductase, 4VR; PFAM: 4-vinyl reductase, 4VR; SPTR: 4-vinyl reductase, 4VR; PFAM: V4R domain YP_004371064.1 COGs: COG0152 phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; HAMAP: SAICAR synthetase; InterPro IPR001636; KEGG: dol:Dole_2369 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: SAICAR synthetase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase YP_004371065.1 COGs: COG0515 Serine/threonine protein kinase; InterPro IPR017442:IPR002290:IPR020635; KEGG: sro:Sros_7672 serine/threonine protein kinase-like protein; PFAM: Serine/threonine-protein kinase-like domain; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, catalytic domain; SPTR: Serine/threonine protein kinase-like protein; PFAM: protein kinase domain YP_004371067.1 COGs: COG2956 N-acetylglucosaminyl transferase; InterPro IPR001440:IPR013105:IPR011717:IPR019734; KEGG: dbr:Deba_3097 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; Tetratricopeptide TPR-4; SPTR: uncharacterized protein; PFAM: ChAPs (Chs5p-Arf1p-binding proteins); Tetratricopeptide repeat YP_004371068.1 COGs: COG0518 GMP synthase - glutamine amidotransferase domain; InterPro IPR000991; KEGG: tjr:TherJR_0913 glutamine amidotransferase class-I; PFAM: glutamine amidotransferase class-I, C-terminal; SPTR: glutamine amidotransferase class-I; PFAM: glutamine amidotransferase class-I YP_004371069.1 InterPro IPR007272; KEGG: ppd:Ppro_1978 protein of unknown function DUF395, YeeE/YedE; PFAM: Domain of unknown function DUF395, YeeE/YedE; SPTR: uncharacterized protein; PFAM: YeeE/YedE family (DUF395) YP_004371070.1 InterPro IPR007272; KEGG: dol:Dole_3014 protein of unknown function DUF395 YeeE/YedE; PFAM: Domain of unknown function DUF395, YeeE/YedE; SPTR: uncharacterized protein; PFAM: YeeE/YedE family (DUF395) YP_004371071.1 KEGG: slt:Slit_0957 hypothetical protein; SPTR: uncharacterized protein YP_004371072.1 COGs: COG0588 phosphoglycerate mutase 1; HAMAP: phosphoglycerate mutase 1; InterPro IPR005952:IPR013078; KEGG: gme:Gmet_1653 phosphoglyceromutase; PFAM: histidine phosphatase superfamily, clade-1; PRIAM: Bisphosphoglycerate mutase; SMART: histidine phosphatase superfamily, clade-1; SPTR: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; TIGRFAM: phosphoglycerate mutase 1; PFAM: phosphoglycerate mutase; TIGRFAM: phosphoglycerate mutase, BPG-dependent, family 1 YP_004371073.1 COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: nde:NIDE3222 deacetylase, histone deacetylase; PFAM: histone deacetylase superfamily; SPTR: Deacetylase, histone deacetylase; PFAM: histone deacetylase domain YP_004371074.1 COGs: COG4252 transmembrane sensor domain; InterPro IPR007890:IPR001054; KEGG: sat:SYN_01481 adenylate cyclase; PFAM: CHASE2; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: adenylate/guanylate cyclase with Chase sensor; PFAM: adenylate and Guanylate cyclase catalytic domain; CHASE2 domain YP_004371077.1 COGs: COG1217 membrane GTPase involved in stress response; InterProIPR005225:IPR006298:IPR000795:IPR004161:IPR 000640; KEGG: sfu:Sfum_2868 GTP-binding protein TypA; PFAM: protein synthesis factor, GTP-binding; translation elongation factor EFTu/EF1A, domain 2; translation elongation factor EFG/EF2, C-terminal; SPTR: GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-binding protein domain YP_004371078.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: tye:THEYE_A1646 ABC-type multidrug transport system, ATPase component; PFAM: ABC transporter-like; PRIAM: sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC-type multidrug transport system, ATPase component; PFAM: ABC transporter YP_004371079.1 COGs: COG2122 conserved hypothetical protein; InterPro IPR003374; KEGG: dbr:Deba_1296 ApbE family lipoprotein; PFAM: Thiamine synthesis ApbE/UPF0280; SPTR: uncharacterized protein; PFAM: ApbE family YP_004371080.1 InterPro IPR000620; KEGG: sat:SYN_00035 DMT family permease; PFAM: Drug/metabolite transporter; SPTR: Permease of the DMT superfamily; PFAM: EamA-like transporter family YP_004371081.1 COGs: COG1104 cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: geo:Geob_2507 aminotransferase class V; PFAM: Aminotransferase, class V/cysteine desulfurase; PRIAM: cysteine desulfurase; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V YP_004371082.1 KEGG: dal:Dalk_0015 hypothetical protein; SPTR: uncharacterized protein YP_004371083.1 COGs: COG0474 Cation transport ATPase; InterProIPR001757:IPR004014:IPR008250:IPR005834:IPR 006068; KEGG: mpd:MCP_2677 cation-transporting ATPase; PFAM: ATPase, P-type, ATPase-associated domain; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase; ATPase, P-type cation-transporter, C-terminal; PRIAM: Calcium-transporting ATPase; SMART: ATPase, P-type cation-transporter, N-terminal; SPTR: Cation-transporting ATPase; TIGRFAM: ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; haloacid dehalogenase-like hydrolase; Cation transporter/ATPase, N-terminus; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004371084.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: nhl:Nhal_1697 glycosyl transferase group 1; PFAM: glycosyl transferase, group 1; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1 YP_004371085.1 COGs: COG4651 Kef-type K+ transport system predicted NAD-binding component; InterPro IPR006153:IPR003148:IPR006037; KEGG: dol:Dole_0855 sodium/hydrogen exchanger; PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; SPTR: Sodium/hydrogen exchanger; PFAM: TrkA-N domain; TrkA-C domain; Sodium/hydrogen exchanger family; TIGRFAM: transporter, monovalent cation:proton antiporter-2 (CPA2) family YP_004371086.1 InterPro IPR000644; KEGG: tye:THEYE_A0728 CBS domain pair, PFAM: cystathionine beta-synthase, core; SMART: cystathionine beta-synthase, core; SPTR: CBS domain pair, ; PFAM: CBS domain YP_004371087.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279; KEGG: dal:Dalk_4372 beta-lactamase domain protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily YP_004371088.1 COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184; KEGG: sfu:Sfum_0758 surface antigen (D15); PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Surface antigen (D15); PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein YP_004371089.1 COGs: COG2911 conserved hypothetical protein; InterPro IPR007452; KEGG: sfu:Sfum_0830 hypothetical protein; PFAM: protein of unknown function DUF490; SPTR: uncharacterized protein; PFAM: Family of unknown function (DUF490) YP_004371090.1 COGs: COG3178 phosphotransferase related to Ser/Thr protein kinase; InterPro IPR002575; KEGG: sfu:Sfum_0532 aminoglycoside phosphotransferase; PFAM: Aminoglycoside phosphotransferase; SPTR: Aminoglycoside phosphotransferase; PFAM: phosphotransferase enzyme family YP_004371091.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: bae:BATR1942_03430 YjbJ protein; PFAM: Lytic transglycosylase-like, catalytic; SPTR: murein lytic transglycosylase; PFAM: transglycosylase SLT domain YP_004371092.1 COGs: COG2064 Flp pilus assembly protein TadC; InterPro IPR018076; KEGG: sat:SYN_01499 flp pilus assembly protein; PFAM: Type II secretion system F domain; SPTR: Flp pilus assembly protein; PFAM: Bacterial type II secretion system protein F domain YP_004371093.1 COGs: COG4965 Flp pilus assembly protein TadB; InterPro IPR018076; KEGG: pol:Bpro_2556 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: Type II secretion system protein; PFAM: Bacterial type II secretion system protein F domain YP_004371094.1 COGs: COG4962 Flp pilus assembly protein ATPase CpaF; InterPro IPR001482; KEGG: sfu:Sfum_1498 type II secretion system protein E; PFAM: Type II secretion system protein E; SPTR: Type II secretion system protein E; PFAM: Type II/IV secretion system protein YP_004371095.1 COGs: COG4963 Flp pilus assembly protein ATPase CpaE; KEGG: dma:DMR_33830 hypothetical protein; SPTR: uncharacterized protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004371096.1 COGs: COG3745 Flp pilus assembly protein CpaB; InterPro IPR017592:IPR013974; KEGG: nmu:Nmul_A2361 Flp pilus assembly CpaB; PFAM: SAF domain; SMART: SAF domain; SPTR: Flp pilus assembly CpaB; TIGRFAM: Pilus assembly, Flp-type CpaB; PFAM: SAF domain; TIGRFAM: Flp pilus assembly protein CpaB YP_004371097.1 InterPro IPR007047; KEGG: reu:Reut_A2639 Flp/Fap pilin component; PFAM: Flp/Fap pilin component; SPTR: Flp/Fap pilin component; PFAM: Flp/Fap pilin component YP_004371098.1 InterPro IPR007047; KEGG: bvi:Bcep1808_1483 Flp/Fap pilin component; PFAM: Flp/Fap pilin component; SPTR: Flp/Fap pilin component; PFAM: Flp/Fap pilin component YP_004371099.1 KEGG: sat:SYN_00051 ATPase with chaperone activity; SPTR: Predicted ATPase with chaperone activity YP_004371100.1 KEGG: dal:Dalk_4212 hypothetical protein; SPTR: uncharacterized protein YP_004371101.1 COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: dbr:Deba_2700 histone family protein DNA-binding protein; PFAM: histone-like bacterial DNA-binding protein; SMART: histone-like bacterial DNA-binding protein; SPTR: histone family protein DNA-binding protein; PFAM: Bacterial DNA-binding protein; TIGRFAM: integration host factor, beta subunit YP_004371102.1 COGs: COG0504 CTP synthase (UTP-ammonia lyase); HAMAP: CTP synthase; InterPro IPR004468:IPR017456:IPR000991; KEGG: dbr:Deba_1475 CTP synthase; PFAM: CTP synthase, N-terminal; glutamine amidotransferase class-I, C-terminal; PRIAM: CTP synthase; SPTR: CTP synthase; TIGRFAM: CTP synthase; PFAM: glutamine amidotransferase class-I; CTP synthase N-terminus; TIGRFAM: CTP synthase YP_004371103.1 COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; HAMAP: 3-deoxy-8-phosphooctulonate synthase; InterPro IPR006269:IPR006218; KEGG: gme:Gmet_1277 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-8-phosphooctulonate synthase; SPTR: 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase YP_004371104.1 COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR010023:IPR006549:IPR013200; KEGG: tkm:TK90_0366 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; PFAM: HAD superfamily hydrolase-like, type 3; PRIAM: 3-deoxy-manno-octulosonate-8-phosphatase; SPTR: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; HAD-superfamily hydrolase, subfamily IIIA YP_004371105.1 InterPro IPR010664; KEGG: sfu:Sfum_2072 hypothetical protein; PFAM: Lipopolysccharide assembly, LptC-related; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1239) YP_004371106.1 COGs: COG1934 conserved hypothetical protein; InterPro IPR005653; KEGG: dbr:Deba_1959 lipopolysaccharide transport periplasmic protein LptA; PFAM: Organic solvent tolerance-like, N-terminal; SPTR: Lipopolysaccharide transport periplasmic protein LptA; PFAM: OstA-like protein; TIGRFAM: lipopolysaccharide transport periplasmic protein LptA YP_004371107.1 COGs: COG1137 ABC-type (unclassified) transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sat:SYN_00946 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter YP_004371108.1 COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: dat:HRM2_27870 RpoN; PFAM: RNA polymerase sigma factor 54, DNA-binding; RNA polymerase sigma factor 54, core-binding; RNA polymerase sigma factor 54; SPTR: RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma factor 54; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor YP_004371109.1 COGs: COG1544 ribosome-associated protein Y (PSrp-1); InterPro IPR003489; KEGG: gsu:GSU1886 ribosomal subunit interface protein; PFAM: ribosomal protein S30Ae/sigma 54 modulation protein; SPTR: ribosomal subunit interface protein; TIGRFAM: ribosomal protein S30Ae/sigma 54 modulation protein; PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein YP_004371110.1 COGs: COG1762 phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: sat:SYN_00943 nitrogen regulatory IIA protein; PFAM: phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: nitrogen regulatory IIA protein; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_004371111.1 COGs: COG1660 P-loop-containing kinase; HAMAP: ATPase, P-loop-containing; InterPro IPR005337; KEGG: dal:Dalk_1358 hypothetical protein; SPTR: UPF0042 nucleotide-binding protein Dalk_1358; PFAM: P-loop ATPase YP_004371112.1 COGs: COG2893 phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: dol:Dole_0502 PTS system fructose subfamily IIA component; PFAM: phosphotransferase system, fructose subfamily IIA component; SPTR: PTS system fructose subfamily IIA component; PFAM: PTS system fructose IIA component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component YP_004371113.1 COGs: COG0456 Acetyltransferase; InterPro IPR006464:IPR000182; KEGG: afw:Anae109_2472 ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: ribosomal-protein-alanine acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: Acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase YP_004371114.1 COGs: COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); HAMAP: NAD(P)H-quinone oxidoreductase, subunit N/subunit 2; InterPro IPR010096:IPR001750; KEGG: gme:Gmet_3342 proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase subunit N 2; TIGRFAM: NAD(P)H-quinone oxidoreductase, subunit N/subunit 2; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N YP_004371115.1 COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR010227:IPR001750; KEGG: gme:Gmet_3343 proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: Similar to NADH:ubiquinone oxidoreductase subunit M; TIGRFAM: NADH-quinone oxidoreductase, chain M/4; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-ubiquinone oxidoreductase chain 4, amino terminus; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M YP_004371116.1 COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR003945:IPR001516:IPR001750; KEGG: gme:Gmet_3344 NADH-plastoquinone oxidoreductase, chain 5; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; NADH:ubiquinone oxidoreductase, chain 5/L, N-terminal; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH:quinone oxidoreductase subunit L; TIGRFAM: NADH-plastoquinone oxidoreductase, chain 5; PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5 C-terminus; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L YP_004371117.1 COGs: COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); HAMAP: NADH-ubiquinone oxidoreductase chain 4L/K; InterPro IPR001133; KEGG: geo:Geob_0472 NADH-ubiquinone oxidoreductase chain 4L; PFAM: NADH-ubiquinone oxidoreductase chain 4L/K; SPTR: NADH-quinone oxidoreductase subunit K 1; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L YP_004371118.1 COGs: COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J); InterPro IPR001457; KEGG: gsu:GSU0347 NADH dehydrogenase I subunit J; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase, chain 6; SPTR: NADH dehydrogenase I, J subunit; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6 YP_004371119.1 COGs: COG1143 formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); HAMAP: NADH-quinone oxidoreductase, chain I; InterPro IPR010226:IPR001450; KEGG: chl:Chy400_3142 NADH-quinone oxidoreductase, chain I; PFAM: 4Fe-4S binding domain; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase subunit I; TIGRFAM: NADH-quinone oxidoreductase, chain I; PFAM: 4Fe-4S binding domain; TIGRFAM: NADH-quinone oxidoreductase, chain I YP_004371120.1 COGs: COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); InterPro IPR001694; KEGG: gme:Gmet_0161 respiratory-chain NADH dehydrogenase subunit 1; PFAM: NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase chain H (NADH dehydrogenase I, chain H) (NDH-1, chain H); PFAM: NADH dehydrogenase YP_004371121.1 COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR001041:IPR019574:IPR001450:IPR006963:IPR 006656:IPR006657; KEGG: chy:CHY_0733 NAD-dependent formate dehydrogenase, alpha subunit, selenocysteine-containing; PFAM: Molybdopterin oxidoreductase; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S binding domain; Molybdopterin oxidoreductase, Fe4S4 domain; Molydopterin dinucleotide-binding domain; PRIAM: NADH dehydrogenase (quinone); SMART: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Molybdopterin oxidoreductase, Fe4S4 domain; SPTR: NAD-dependent formate dehydrogenase, alpha subunit, selenocysteine-containing; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Molybdopterin oxidoreductase Fe4S4 domain YP_004371122.1 COGs: COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7; HAMAP: NAD(P)H-quinone oxidoreductase subunit D/H; InterPro IPR010219:IPR001135:IPR022885; KEGG: gur:Gura_4241 NADH dehydrogenase I, D subunit; PFAM: NADH-quinone oxidoreductase, subunit D; PRIAM: NADH dehydrogenase (quinone); SPTR: Strongly similar to to proton-translocating NADH dehydrogenase I 49 kDa subunit (NuoD); TIGRFAM: NADH dehydrogenase I, subunit D; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit; TIGRFAM: NADH dehydrogenase I, D subunit YP_004371123.1 COGs: COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; HAMAP: NADH dehydrogenase, subunit C; InterPro IPR010218:IPR001268; KEGG: rrs:RoseRS_3676 NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH:ubiquinone oxidoreductase, 30kDa subunit; SPTR: NADH-quinone oxidoreductase subunit C; TIGRFAM: NADH dehydrogenase, subunit C; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C YP_004371124.1 COGs: COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductase; HAMAP: NADH-ubiquinone oxidoreductase, 20 Kd subunit; InterPro IPR006138:IPR006137; KEGG: sna:Snas_1275 NADH-quinone oxidoreductase B subunit; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase subunit B 1; TIGRFAM: NADH-ubiquinone oxidoreductase, 20 Kd subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit YP_004371125.1 COGs: COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A); HAMAP: NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid; InterPro IPR000440:IPR023043; KEGG: gem:GM21_4010 NADH-ubiquinone/plastoquinone oxidoreductase chain 3; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase, chain 3; SPTR: NADH-quinone oxidoreductase subunit; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 YP_004371126.1 COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR002023:IPR011538:IPR019554:IPR019575; KEGG: sat:SYN_02139 NADH-quinone oxidoreductase chain F; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; NADH:ubiquinone oxidoreductase, 24kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: NADH-quinone oxidoreductase chain F; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain YP_004371127.1 COGs: COG1980 fructose 1 6-bisphosphatase; InterPro IPR002803; KEGG: rca:Rcas_3026 hypothetical protein; PFAM: Fructose-1,6-bisphosphatase, class V; SPTR: uncharacterized protein; PFAM: Fructose-1,6-bisphosphatase YP_004371128.1 COGs: COG1720 conserved hypothetical protein; InterPro IPR001378; KEGG: alv:Alvin_3236 protein of unknown function UPF0066; PFAM: Uncharacterised protein family UPF0066; SPTR: uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0066; PFAM: Uncharacterised protein family UPF0066; TIGRFAM: methyltransferase, YaeB/AF_0241 family YP_004371129.1 COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR001450; KEGG: geo:Geob_2072 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_004371130.1 KEGG: cpc:Cpar_1163 hypothetical protein; SPTR: uncharacterized protein YP_004371131.1 COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260; KEGG: tye:THEYE_A0138 TonB domain protein, PFAM: TonB, C-terminal; SPTR: TonB domain protein, ; TIGRFAM: TonB, C-terminal; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain YP_004371132.1 InterPro IPR019300; KEGG: dbr:Deba_1081 RNA-binding protein, predicted; PFAM: RNA-binding protein, predicted; SPTR: RNA-binding protein, predicted; PFAM: Predicted RNA-binding protein YP_004371133.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: mac:MA2152 ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: methyltransferase type 11; SPTR: Ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: methyltransferase domain YP_004371134.1 KEGG: tfu:Tfu_0480 cell wall-associated hydrolase (invasion-associated proteins); SPTR: Similar to Cell wall-associated hydrolases (Invasion-associated proteins) YP_004371135.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: mpt:Mpe_A2804 outer membrane receptor protein; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: Outer membrane receptor protein; PFAM: TonB-dependent Receptor Plug Domain YP_004371136.1 COGs: COG5266 ABC-type Co2+ transport system periplasmic component; InterPro IPR019613; KEGG: oan:Oant_4175 hypothetical protein; PFAM: Nickel transport complex, NikM subunit, transmembrane; SPTR: ABC-type Co2+ transport system, periplasmic component; PFAM: Nickel uptake substrate-specific transmembrane region YP_004371137.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: mpt:Mpe_A2804 outer membrane receptor protein; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: Outer membrane receptor protein; PFAM: TonB-dependent Receptor Plug Domain YP_004371138.1 COGs: COG5266 ABC-type Co2+ transport system periplasmic component; InterPro IPR019613; KEGG: oan:Oant_4175 hypothetical protein; PFAM: Nickel transport complex, NikM subunit, transmembrane; SPTR: ABC-type Co2+ transport system, periplasmic component; PFAM: Nickel uptake substrate-specific transmembrane region YP_004371139.1 COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: abo:ABO_1967 MotA/TolQ/ExbB proton channel family protein; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel family protein; PFAM: MotA/TolQ/ExbB proton channel family YP_004371140.1 COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: pmy:Pmen_3869 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR YP_004371141.1 COGs: COG0823 Periplasmic component of the Tol biopolymer transport system; HAMAP: Tol-Pal system beta propeller repeat-containing protein, TolB; InterPro IPR011659:IPR014167; KEGG: dol:Dole_2210 beta-propeller repeat-containing to-pal system protein TolB; PFAM: WD40-like Beta Propeller; SPTR: protein tolB; PFAM: WD40-like Beta Propeller Repeat; TolB amino-terminal domain; TIGRFAM: tol-pal system beta propeller repeat protein TolB YP_004371142.1 KEGG: dbr:Deba_2431 TonB family protein; SPTR: protein TolA; PFAM: TolA C-terminal; TIGRFAM: TolA protein; TonB family C-terminal domain YP_004371143.1 COGs: COG0848 Biopolymer transport protein; InterPro IPR014168:IPR003400; KEGG: sfu:Sfum_0753 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Biopolymer transport protein ExbD/TolR; TIGRFAM: Biopolymer transport, TolR; PFAM: Biopolymer transport protein ExbD/TolR; TIGRFAM: TolR protein YP_004371144.1 COGs: COG0811 Biopolymer transport protein; InterPro IPR014163:IPR002898; KEGG: dol:Dole_2213 Tol-Pal system TolQ; PFAM: MotA/TolQ/ExbB proton channel; SPTR: protein tolQ; TIGRFAM: Tol-Pal system, TolQ; PFAM: MotA/TolQ/ExbB proton channel family; TIGRFAM: TolQ protein YP_004371145.1 InterPro IPR006683; KEGG: dbr:Deba_1360 thioesterase superfamily protein; PFAM: Thioesterase superfamily; SPTR: Thioesterase superfamily protein; PFAM: Thioesterase superfamily YP_004371146.1 COGs: COG1576 conserved hypothetical protein; HAMAP: SPOUT methyltransferase, predicted; InterPro IPR003742; KEGG: mbn:Mboo_2340 hypothetical protein; PFAM: SPOUT methyltransferase, predicted; SPTR: ribosomal RNA large subunit methyltransferase H; PFAM: Predicted SPOUT methyltransferase; TIGRFAM: rRNA large subunit m3Psi methyltransferase RlmH YP_004371147.1 COGs: COG0694 Thioredoxin-like protein and domains; InterPro IPR001075; KEGG: aar:Acear_1887 nitrogen-fixing NifU domain protein; PFAM: NIF system FeS cluster assembly, NifU, C-terminal; SPTR: nitrogen-fixing NifU domain protein; PFAM: NifU-like domain YP_004371148.1 COGs: COG2968 conserved hypothetical protein; InterPro IPR007497; KEGG: zmo:ZMO0286 hypothetical protein; PFAM: protein of unknown function DUF541; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF541) YP_004371149.1 COGs: COG1995 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; InterPro IPR005255; KEGG: dat:HRM2_18550 PdxA; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase YP_004371150.1 COGs: COG0015 adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR019468; KEGG: sfu:Sfum_0660 adenylosuccinate lyase; PFAM: Lyase 1, N-terminal; adenylosuccinate lyase C-terminal metazoa/fungi; SPTR: adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Lyase; adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase YP_004371151.1 KEGG: sfu:Sfum_1244 hypothetical protein; SPTR: uncharacterized protein YP_004371152.1 COGs: COG0519 GMP synthase PP-ATPase domain/subunit; HAMAP: GMP synthase; InterProIPR004739:IPR001674:IPR000991:IPR004506:IPR 022955; KEGG: gur:Gura_3123 GMP synthase; PFAM: GMP synthase, C-terminal; glutamine amidotransferase class-I, C-terminal; tRNA-specific 2-thiouridylase; PRIAM: GMP synthase (glutamine-hydrolyzing); SPTR: GMP synthase [glutamine-hydrolyzing]; TIGRFAM: GMP synthase, C-terminal; GMP synthase, N-terminal; PFAM: GMP synthase C terminal domain; glutamine amidotransferase class-I; tRNA methyl transferase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit YP_004371153.1 COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: pth:PTH_0063 DNA polymerase III, gamma/tau subunits; SPTR: DNA polymerase III, delta' subunit; TIGRFAM: DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta' subunit; DNA polymerase III, subunit gamma and tau YP_004371154.1 COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557; KEGG: dal:Dalk_0025 PSP1 domain protein; PFAM: PSP1, C-terminal; SPTR: PSP1 domain protein; PFAM: PSP1 C-terminal conserved region YP_004371155.1 KEGG: dak:DaAHT2_0213 hypothetical protein; SPTR: uncharacterized protein YP_004371156.1 COGs: COG1295 membrane protein; InterPro IPR017039:IPR004664; KEGG: gur:Gura_0638 ribonuclease BN; PFAM: ribonuclease BN-related; SPTR: ribonuclease BN; TIGRFAM: ribonuclease BN; PFAM: ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN) YP_004371157.1 COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: sat:SYN_02589 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: methylglyoxal synthase-like domain; SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit YP_004371158.1 COGs: COG0034 glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: mfv:Mfer_0378 amidophosphoribosyltransferase; PFAM: glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; PFAM: phosphoribosyl transferase domain; TIGRFAM: amidophosphoribosyltransferase YP_004371159.1 COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR001387; KEGG: pfu:PF1356 glucose-1-phosphate uridylyltransferase; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: glucose-1-phosphate uridylyltransferase; PFAM: nucleotidyl transferase; Helix-turn-helix YP_004371160.1 InterPro IPR002781; KEGG: sfu:Sfum_2931 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004371161.1 COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: sfu:Sfum_2154 methyl-viologen-reducing hydrogenase, delta subunit; PFAM: methyl-viologen-reducing hydrogenase, delta subunit; SPTR: methyl-viologen-reducing hydrogenase, delta subunit; PFAM: methyl-viologen-reducing hydrogenase, delta subunit YP_004371162.1 COGs: COG0603 PP-loop superfamily ATPase; InterPro IPR018317; KEGG: paa:Paes_0681 ExsB protein; PFAM: Queuosine synthesis; SPTR: 7-cyano-7-deazaguanine synthase; TIGRFAM: Queuosine synthesis; PFAM: ExsB; TIGRFAM: queuosine biosynthesis protein QueC YP_004371163.1 COGs: COG0602 Organic radical activating protein; InterPro IPR007197; KEGG: min:Minf_1288 organic radical activating enzyme; PFAM: Radical SAM; SPTR: Organic radical activating enzyme; PFAM: Radical SAM superfamily YP_004371164.1 KEGG: mgm:Mmc1_3433 phosphoglucomutase; SPTR: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; manually curated YP_004371165.1 COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: bhy:BHWA1_01078 sporulation initiation inhibitor protein Soj; PFAM: cobyrinic acid a,c-diamide synthase; SPTR: Sporulation initiation inhibitor protein Soj; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004371166.1 COGs: COG0345 Pyrroline-5-carboxylate reductase; InterPro IPR000304:IPR004455; KEGG: scl:sce5868 hypothetical protein; PFAM: NADP oxidoreductase, coenzyme F420-dependent; PRIAM: Pyrroline-5-carboxylate reductase; SPTR: Pyrroline-5-carboxylate reductase; TIGRFAM: Pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase YP_004371167.1 COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR004393:IPR022412:IPR002638; KEGG: pth:PTH_0226 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal; PRIAM: Nicotinate-nucleotide diphosphorylase (carboxylating); SPTR: Nicotinate-nucleotide pyrophosphorylase; TIGRFAM: Nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase YP_004371168.1 KEGG: pva:Pvag_1200 hypothetical protein; SPTR: uncharacterized protein YP_004371169.1 COGs: COG1533 DNA repair photolyase; KEGG: dak:DaAHT2_0074 DNA repair photolyase-like protein; SPTR: DNA repair photolyase-like protein YP_004371170.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: dps:DP2867 ferric uptake regulatory protein; PFAM: Ferric-uptake regulator; SPTR: uncharacterized protein; PFAM: Ferric uptake regulator family YP_004371171.1 COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR007202; KEGG: dak:DaAHT2_0716 Fe-S cluster domain protein; PFAM: Fe-S cluster; SPTR: Fe-S cluster domain protein; PFAM: Fe-S cluster YP_004371172.1 KEGG: dal:Dalk_5094 hypothetical protein; SPTR: uncharacterized protein YP_004371173.1 KEGG: dat:HRM2_40770 hypothetical protein; SPTR: uncharacterized protein YP_004371174.1 COGs: COG1592 Rubrerythrin; InterPro IPR003251:IPR004039; KEGG: tye:THEYE_A0161 rubrerythrin; PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein; SPTR: uncharacterized protein; PFAM: Rubrerythrin YP_004371175.1 COGs: COG2033 Desulfoferrodoxin; InterPro IPR004462:IPR004793:IPR002742; KEGG: dma:DMR_17610 desulfoferrodoxin; PFAM: Desulfoferrodoxin, ferrous iron-binding domain; Desulfoferrodoxin Dfx; SPTR: Desulfoferrodoxin; TIGRFAM: Desulfoferrodoxin; Desulfoferrodoxin Dfx; Desulfoferrodoxin, ferrous iron-binding domain; PFAM: Desulfoferrodoxin, N-terminal domain; Desulfoferrodoxin; TIGRFAM: desulfoferrodoxin FeS4 iron-binding domain; desulfoferrodoxin; desulfoferrodoxin ferrous iron-binding domain YP_004371176.1 COGs: COG0674 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR022367:IPR019752:IPR002880; KEGG: dak:DaAHT2_0202 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; PFAM: domain; pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit YP_004371177.1 COGs: COG1013 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011896:IPR011766; KEGG: dbr:Deba_1037 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: 2-oxoglutarate synthase; SPTR: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; PFAM: pyruvate ferredoxin oxidoreductase beta subunit C terminal; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family YP_004371178.1 COGs: COG1773 Rubredoxin; InterPro IPR004039; KEGG: dma:DMR_19810 rubredoxin; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin; PFAM: Rubredoxin YP_004371179.1 COGs: COG1773 Rubredoxin; InterPro IPR004039; KEGG: tye:THEYE_A1651 rubredoxin; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin; PFAM: Rubredoxin YP_004371180.1 COGs: COG0426 flavoprotein; InterPro IPR001279:IPR008254; KEGG: sfu:Sfum_3253 flavodoxin/nitric oxide synthase; PFAM: Flavodoxin/nitric oxide synthase; Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Flavodoxin/nitric oxide synthase; PFAM: Flavodoxin; Metallo-beta-lactamase superfamily YP_004371181.1 COGs: COG0417 DNA polymerase elongation subunit (family B); InterPro IPR006172:IPR006134; KEGG: lbf:LBF_2104 DNA-directed DNA polymerase; PFAM: DNA-directed DNA polymerase, family B, conserved region; SMART: DNA-directed DNA polymerase, family B; SPTR: DNA polymerase B region; PFAM: DNA polymerase B YP_004371182.1 KEGG: lbf:LBF_3369 hypothetical protein; SPTR: uncharacterized protein YP_004371183.1 COGs: COG1943 transposase and inactivated derivatives; KEGG: cyh:Cyan8802_3252 hypothetical protein; SPTR: uncharacterized protein; PFAM: transposase IS200 like YP_004371184.1 KEGG: mse:Msed_1215 hypothetical protein; SPTR: Chromosome segregation protein SMC YP_004371185.1 KEGG: gdj:Gdia_2776 hypothetical protein; SPTR: uncharacterized protein YP_004371186.1 KEGG: cak:Caul_2775 hypothetical protein; SPTR: uncharacterized protein YP_004371187.1 KEGG: aba:Acid345_0955 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function, DUF488 YP_004371188.1 KEGG: cyb:CYB_0386 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function, DUF488 YP_004371189.1 KEGG: lbf:LBF_2103 hypothetical protein; SPTR: uncharacterized protein YP_004371190.1 InterPro IPR008815; KEGG: aca:ACP_1829 hypothetical protein; PFAM: 23S rRNA-associated protein; SPTR: uncharacterized protein; PFAM: S23 ribosomal protein YP_004371191.1 COGs: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidase); HAMAP: peptidase S24, LexA repressor; InterPro IPR006199:IPR019759:IPR006200; KEGG: gsu:GSU1617 LexA repressor; PFAM: LexA, DNA-binding domain; peptidase S24/S26A/S26B, conserved region; SPTR: LexA repressor; TIGRFAM: peptidase S24, LexA repressor; PFAM: LexA DNA binding domain; peptidase S24-like; TIGRFAM: SOS regulatory protein LexA YP_004371192.1 InterPro IPR003646:IPR010466:IPR013247; KEGG: dak:DaAHT2_2324 protein of unknown function DUF1058; PFAM: SH3, type 3; protein of unknown function DUF1058; SMART: SH3-like domain, bacterial; SPTR: uncharacterized protein; PFAM: Bacterial SH3 domain YP_004371193.1 COGs: COG0436 aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: dol:Dole_1584 aspartate aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: aspartate transaminase; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II YP_004371194.1 COGs: COG3688 RNA-binding protein containing a PIN domain; InterPro IPR010298; KEGG: sat:SYN_01764 cytoplasmic protein; PFAM: protein of unknown function DUF901; SPTR: Hypothetical cytosolic protein; PFAM: protein of unknown function (DUF901) YP_004371195.1 KEGG: rrs:RoseRS_2769 FHA domain-containing protein; SPTR: FHA domain containing protein YP_004371196.1 InterPro IPR003646:IPR013247; KEGG: tcr:509265.110 trans-sialidase; PFAM: SH3, type 3; SMART: SH3-like domain, bacterial; SPTR: trans-sialidase, ; PFAM: Bacterial SH3 domain YP_004371197.1 COGs: COG0332 3-oxoacyl-(acyl-carrier-protein); HAMAP: Beta-ketoacyl-acyl carrier protein synthase III (FabH); InterPro IPR013751:IPR013747:IPR004655; KEGG: gym:GYMC10_4246 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase I; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase 3; TIGRFAM: Beta-ketoacyl-acyl carrier protein synthase III (FabH); PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III YP_004371198.1 COGs: COG1322 conserved hypothetical protein; InterPro IPR003798; KEGG: gur:Gura_0571 hypothetical protein; PFAM: DNA recombination RmuC; SPTR: uncharacterized protein; PFAM: RmuC family YP_004371199.1 InterPro IPR011449; KEGG: rfr:Rfer_0835 hypothetical protein; PFAM: PEP-CTERM bacterial; SPTR: uncharacterized protein YP_004371201.1 COGs: COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis; InterPro IPR003856; KEGG: gur:Gura_2580 lipopolysaccharide biosynthesis protein; PFAM: Lipopolysaccharide biosynthesis; SPTR: uncharacterized protein; PFAM: Chain length determinant protein YP_004371202.1 COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR005702; KEGG: sat:SYN_00779 tyrosine-protein kinase; SPTR: Tyrosine-protein kinase; TIGRFAM: Exopolysaccharide synthesis protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: capsular exopolysaccharide family YP_004371203.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362:IPR017475; KEGG: gme:Gmet_2031 sugar transferase; PFAM: Bacterial sugar transferase; SPTR: Similar to glycosyl transferase; TIGRFAM: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase YP_004371204.1 InterPro IPR019127:IPR013426:IPR014263; KEGG: sat:SYN_01097 hypothetical protein; PFAM: Exosortase EpsH-related; SPTR: Hypothetical membrane protein; TIGRFAM: methanolan biosynthesis EpsI; Exosortase, EpsH; PFAM: protein of unknown function (DUF3485); transmembrane exosortase (Exosortase_EpsH); TIGRFAM: EpsI family protein; eight transmembrane protein EpsH (proposed exosortase) YP_004371205.1 KEGG: cyh:Cyan8802_2822 protein of unknown function UPF0150; SPTR: uncharacterized protein YP_004371206.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: sfu:Sfum_3330 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase YP_004371207.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: sun:SUN_0096 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein YP_004371208.1 InterPro IPR001451; KEGG: nam:NAMH_1717 acetyltransferase, CysE/LacA/LpxA/NodL family; SPTR: Carbonic anhydrase/acetyltransferase isoleucine patch superfamily-like protein YP_004371209.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: lhk:LHK_00843 DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase YP_004371210.1 KEGG: sac:SACOL0052 glycosyl transferase, group 1 family protein; SPTR: uncharacterized protein YP_004371211.1 InterPro IPR001296; KEGG: mru:mru_1886 hypothetical protein; PFAM: glycosyl transferase, group 1; SPTR: uncharacterized protein YP_004371212.1 InterPro IPR007016; KEGG: dsa:Desal_2430 hypothetical protein; PFAM: O-antigen ligase-related; SPTR: uncharacterized protein YP_004371213.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: cpr:CPR_0459 glycosyltransferase, PFAM: glycosyl transferase, group 1; SPTR: glycosytransferase; PFAM: glycosyl transferases group 1 YP_004371214.1 COGs: COG1541 Coenzyme F390 synthetase; KEGG: pgn:PGN_0228 probable coenzyme F390 synthetase; SPTR: Probable coenzyme F390 synthetase; PFAM: AMP-binding enzyme YP_004371215.1 InterPro IPR012480; KEGG: nde:NIDE2386 hypothetical protein; PFAM: Heparinase II/III-like; SPTR: uncharacterized protein; PFAM: Heparinase II/III-like protein YP_004371216.1 COGs: COG1922 Teichoic acid biosynthesis protein; InterPro IPR004629; KEGG: gtn:GTNG_3094 teichoic acid biosynthesis proteins; PFAM: glycosyl transferase WecB/TagA/CpsF; PRIAM: N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase; SPTR: glycosyltransferase, WecB/TagA/CpsF family; TIGRFAM: glycosyl transferase WecB/TagA/CpsF; PFAM: glycosyl transferase WecB/TagA/CpsF family; TIGRFAM: bacterial polymer biosynthesis proteins, WecB/TagA/CpsF family YP_004371217.1 InterPro IPR006626; KEGG: aba:Acid345_0662 parallel beta-helix repeat-containing protein; SPTR: uncharacterized protein YP_004371218.1 COGs: COG4397 Mu-like prophage major head subunit gpT; InterPro IPR018774; KEGG: sat:SYN_02298 Mu-like prophage major head subunit; PFAM: Mu-like major head subunit gpT, prophage; SPTR: Mu-like prophage major head subunit; PFAM: Mu-like prophage major head subunit gpT YP_004371219.1 KEGG: rcu:RCOM_1817840 hypothetical protein; SPTR: uncharacterized protein YP_004371220.1 COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: sfu:Sfum_3318 peptidase M24; PFAM: peptidase M24, structural domain; Creatinase; SPTR: peptidase M24; PFAM: Metallopeptidase M24; Creatinase/Prolidase N-terminal domain YP_004371221.1 COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: msv:Mesil_1094 protein of unknown function DUF162; PFAM: Domain of unknown function DUF162; SPTR: uncharacterized protein; PFAM: Uncharacterised ACR, YkgG family COG1556 YP_004371222.1 COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR003741:IPR001450; KEGG: cag:Cagg_2719 iron-sulfur cluster binding protein; PFAM: Domain of unknown function DUF162; 4Fe-4S binding domain; SPTR: Iron-sulfur cluster binding protein; PFAM: Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein YP_004371223.1 KEGG: dma:DMR_17550 hypothetical membrane protein; SPTR: Hypothetical membrane protein YP_004371224.1 InterPro IPR000297; KEGG: pca:Pcar_1050 peptidyl-prolyl cis-trans isomerase; PFAM: peptidyl-prolyl cis-trans isomerase, PpiC-type; SPTR: uncharacterized protein; PFAM: PPIC-type PPIASE domain YP_004371225.1 COGs: COG1729 conserved hypothetical protein; KEGG: gsu:GSU0023 TPR domain protein; SPTR: TPR domain protein; TIGRFAM: tol-pal system protein YbgF YP_004371226.1 COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665:IPR014169; KEGG: dbr:Deba_2429 peptidoglycan-associated lipoprotein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: peptidoglycan-associated lipoprotein; TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA family; TIGRFAM: peptidoglycan-associated lipoprotein YP_004371227.1 KEGG: sjj:SPJ_2217 surface protein PspC; SPTR: uncharacterized protein YP_004371228.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: sat:SYN_01995 export ABC transporter permease; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: ABC transporter, membrane protein; PFAM: Predicted permease YP_004371229.1 InterPro IPR003675; KEGG: dma:DMR_10780 hypothetical membrane protein; PFAM: Abortive infection protein; SPTR: Hypothetical membrane protein YP_004371230.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: bcr:BCAH187_A0961 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC superfamily ATP binding cassette transporter, ABC protein; PFAM: ABC transporter YP_004371231.1 COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: sat:SYN_01993 periplasmic component of efflux system; PFAM: Secretion protein HlyD; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004371232.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: gur:Gura_3409 outer membrane efflux protein; PFAM: Outer membrane efflux protein; SPTR: Outer membrane efflux protein; PFAM: Outer membrane efflux protein; TIGRFAM: type I secretion outer membrane protein, TolC family YP_004371233.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834:IPR006402; KEGG: pph:Ppha_1044 HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Haloacid dehalogenase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004371234.1 KEGG: afw:Anae109_1251 non-specific protein-tyrosine kinase; SPTR: uncharacterized protein YP_004371235.1 InterPro IPR001763; KEGG: gur:Gura_3920 rhodanese domain-containing protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Rhodanese domain protein; PFAM: Rhodanese-like domain YP_004371236.1 KEGG: gme:Gmet_3019 methylamine utilization protein MauE; SPTR: methylamine utilization protein MauE, ; PFAM: methylamine utilisation protein MauE YP_004371237.1 KEGG: sfu:Sfum_1264 hypothetical protein; SPTR: uncharacterized protein YP_004371238.1 COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003672; KEGG: glo:Glov_3671 cobaltochelatase; PFAM: CobN/magnesium chelatase; PRIAM: Magnesium chelatase; SPTR: Cobaltochelatase; PFAM: CobN/Magnesium Chelatase YP_004371239.1 COGs: COG4744 conserved hypothetical protein; InterPro IPR018676; KEGG: glo:Glov_3672 hypothetical protein; PFAM: protein of unknown function DUF2149; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2149) YP_004371240.1 KEGG: ppd:Ppro_1234 MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family YP_004371241.1 InterPro IPR017199; KEGG: ppd:Ppro_1235 transporter-like protein; PFAM: Uncharacterised conserved protein UCP037409, membrane transporter, MTH672; SPTR: transporter-like protein; PFAM: Predicted transporter (DUF2162) YP_004371242.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: sfu:Sfum_0492 TonB-dependent receptor; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; SPTR: uncharacterized protein; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004371243.1 COGs: COG1010 Precorrin-3B methylase; InterPro IPR000878:IPR006363; KEGG: dal:Dalk_0452 precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-3B C(17)-methyltransferase; SPTR: Precorrin-3B C(17)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: precorrin-3B C17-methyltransferase YP_004371244.1 COGs: COG2073 Cobalamin biosynthesis protein CbiG; InterPro IPR002750; KEGG: dbr:Deba_2462 cobalamin (vitamin B12) biosynthesis CbiG protein; PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; SPTR: protein CbiG; PFAM: Cobalamin biosynthesis central region; Cobalamin synthesis G C-terminus; Cobalamin synthesis G N-terminal YP_004371245.1 COGs: COG2875 Precorrin-4 methylase; InterPro IPR000878:IPR006362; KEGG: sfu:Sfum_2129 precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: Precorrin-4 C11-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: precorrin-4 C11-methyltransferase YP_004371246.1 COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR000878:IPR012818:IPR014008; KEGG: dbr:Deba_2460 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit YP_004371247.1 COGs: COG1903 Cobalamin biosynthesis protein CbiD; HAMAP: Cobalamin (vitamin B12) biosynthesis CbiD; InterPro IPR002748; KEGG: dbr:Deba_2459 cobalamin biosynthesis protein CbiD; PFAM: Cobalamin (vitamin B12) biosynthesis CbiD; SPTR: Cobalamin biosynthesis protein CbiD; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiD; PFAM: CbiD; TIGRFAM: cobalamin biosynthesis protein CbiD YP_004371248.1 COGs: COG2243 Precorrin-2 methylase; InterPro IPR000878:IPR006364; KEGG: sfu:Sfum_2135 precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Precorrin-2 C20-methyltransferase / cobalt-factor II C20-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobI/CbiL, precorrin-2 C20-methyltransferase, core; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: precorrin-2 C20-methyltransferase YP_004371249.1 COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: dal:Dalk_0445 precorrin-8X methylmutase CbiC/CobH; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase YP_004371250.1 COGs: COG1797 cobyrinic acid a c-diamide synthase; HAMAP: cobyrinic acid a,c-diamide synthase CbiA; InterPro IPR002586:IPR011698:IPR004484; KEGG: dal:Dalk_0444 cobyrinic acid a,c-diamide synthase; PFAM: CobB/CobQ-like glutamine amidotransferase; cobyrinic acid a,c-diamide synthase; SPTR: cobyrinic acid a,c-diamide synthase; TIGRFAM: cobyrinic acid a,c-diamide synthase CbiA; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyrinic acid a,c-diamide synthase YP_004371251.1 COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: dat:HRM2_07700 CbiK2; PFAM: Anaerobic cobalt chelatase; PRIAM: Sirohydrochlorin cobaltochelatase; SPTR: uncharacterized protein; PFAM: Cobalt chelatase (CbiK) YP_004371252.1 COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: dvm:DvMF_3139 cobalt transport protein CbiM; PFAM: Cobalamin (vitamin B12) biosynthesis CbiM; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiM protein; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM YP_004371253.1 KEGG: dol:Dole_1530 hypothetical protein; SPTR: uncharacterized protein YP_004371254.1 COGs: COG1858 Cytochrome c peroxidase; KEGG: gsu:GSU2811 cytochrome c Hsc; SPTR: Cytochrome c Hsc YP_004371255.1 COGs: COG2114 adenylate cyclase 3 (some protein contain HAMP domain); InterPro IPR001054:IPR007890; KEGG: sat:SYN_01481 adenylate cyclase; PFAM: CHASE2; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: adenylate cyclase; PFAM: adenylate and Guanylate cyclase catalytic domain; CHASE2 domain YP_004371256.1 COGs: COG1409 phosphohydrolase; InterPro IPR004843:IPR006311; KEGG: nhl:Nhal_1810 metallophosphoesterase; PFAM: Metallo-dependent phosphatase; SPTR: Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase YP_004371257.1 COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: sfu:Sfum_0936 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily; SPTR: histone deacetylase superfamily; PFAM: histone deacetylase domain YP_004371258.1 COGs: COG1042 acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR000182; KEGG: dat:HRM2_37830 SucC4; PFAM: CoA-binding; GCN5-related N-acetyltransferase (GNAT) domain; SMART: CoA-binding; SPTR: acetyl coenzyme A synthetase (ADP forming), alpha domain protein; PFAM: CoA binding domain; Acetyltransferase (GNAT) family YP_004371259.1 KEGG: mar:MAE_33310 hypothetical protein; SPTR: uncharacterized protein YP_004371261.1 KEGG: phu:Phum_PHUM463920 histone-lysine N-methyltransferase SUVR5, SPTR: uncharacterized protein YP_004371262.1 InterPro IPR012933; KEGG: fpl:Ferp_2052 YcfA family protein; PFAM: Uncharacterised protein family UPF0395; SPTR: YcfA family protein; PFAM: YcfA-like protein YP_004371263.1 InterPro IPR005357; KEGG: mta:Moth_2147 2-oxoisovalerate dehydrogenase, E1 component beta subunit; PFAM: Uncharacterised protein family UPF0150; SPTR: 2-oxoisovalerate dehydrogenase, E1 component beta subunit; PFAM: Uncharacterised protein family (UPF0150) YP_004371264.1 KEGG: dal:Dalk_1596 protein of unknown function DUF891; SPTR: uncharacterized protein; PFAM: Phage derived protein Gp49-like (DUF891) YP_004371265.1 InterPro IPR001387; KEGG: nhl:Nhal_0040 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: uncharacterized protein; PFAM: Helix-turn-helix YP_004371266.1 KEGG: nhl:Nhal_0041 hypothetical protein; SPTR: uncharacterized protein YP_004371267.1 COGs: COG0106 phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; HAMAP: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; InterPro IPR006062:IPR006063:IPR023016; KEGG: sfu:Sfum_1215 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidazole-4-carboxamideisomerase; SPTR:1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA; manually curated; PFAM: histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase YP_004371268.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR007197:IPR018768; KEGG: geo:Geob_1240 radical SAM protein; PFAM: protein of unknown function DUF2344; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM family uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2344); Radical SAM superfamily; TIGRFAM: radical SAM family uncharacterized protein; radical SAM-linked protein YP_004371269.1 COGs: COG1530 ribonuclease G and E; InterPro IPR022967:IPR003029:IPR019307:IPR004659; KEGG: gme:Gmet_3192 ribonuclease G; PFAM: RNA-binding protein AU-1/ribonuclease E/G; ribosomal protein S1, RNA-binding domain; SMART: RNA-binding domain, S1; SPTR: ribonuclease, Rne/Rng family; TIGRFAM: ribonuclease E/G; PFAM: ribonuclease E/G family; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family YP_004371270.1 COGs: COG3276 Selenocysteine-specific translation elongation factor; InterProIPR000795:IPR004161:IPR015190:IPR015191:IPR 005225:IPR004535; KEGG: sfu:Sfum_1220 selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor, GTP-binding; translation elongation factor EFTu/EF1A, domain 2; translation elongation factor SelB, winged helix, type 2; translation elongation factor SelB, winged helix, type 3; SPTR: Selenocysteine-specific translation elongation factor SelB; TIGRFAM: translation elongation factor, selenocysteine-specific; Small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Elongation factor SelB, winged helix; TIGRFAM: selenocysteine-specific elongation factor SelB; small GTP-binding protein domain; translation elongation factor TU YP_004371271.1 COGs: COG4783 Zn-dependent protease contains TPR repeats; InterPro IPR001915; KEGG: dde:Dde_0107 lipoprotein; PFAM: peptidase M48; SPTR: Lipoprotein, ; PFAM: peptidase M48 YP_004371273.1 COGs: COG2513 PEP phosphonomutase; InterPro IPR012698; KEGG: scl:sce7305 phosphoenolpyruvate mutase; PRIAM: phosphoenolpyruvate mutase; SPTR: phosphoenolpyruvate mutase; TIGRFAM: phosphoenolpyruvate phosphomutase, core; PFAM: Isocitrate lyase; TIGRFAM: phosphoenolpyruvate phosphomutase; phosphonopyruvate hydrolase YP_004371274.1 COGs: COG4032 thiamine-pyrophosphate-binding protein; InterPro IPR011766:IPR017684; KEGG: noc:Noc_1316 thiamine pyrophosphate enzyme; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: phosphonopyruvate decarboxylase; SPTR: uncharacterized protein; TIGRFAM: phosphonopyruvate decarboxylase; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: phosphonopyruvate decarboxylase YP_004371275.1 COGs: COG1213 sugar nucleotidyltransferase; InterPro IPR005835; KEGG: nde:NIDE0735 sugar nucleotidyltransferase; PFAM: nucleotidyl transferase; SPTR: Sugar nucleotidyltransferase; PFAM: nucleotidyl transferase YP_004371276.1 COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192:IPR017688; KEGG: bfs:BF1899 LPS biosynthesis related 2-aminoethylphosphonate pyruvate aminotransferase; PFAM: Aminotransferase, class V/cysteine desulfurase; PRIAM: 2-aminoethylphosphonate--pyruvate transaminase; SPTR: uncharacterized protein; TIGRFAM: 2-aminoethylphosphonate aminotransferase; PFAM: Aminotransferase class-V; TIGRFAM: 2-aminoethylphosphonate aminotransferase; 2-aminoethylphosphonate--pyruvate transaminase YP_004371277.1 COGs: COG0558 phosphatidylglycerophosphate synthase; InterPro IPR000462; KEGG: nde:NIDE0736 bifunctional sugar nucleotidyltransferase/phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: sugar nucleotidyltransferase and phosphatidyltransferase (bifunctional enzyme); PFAM: CDP-alcohol phosphatidyltransferase YP_004371278.1 InterPro IPR022791:IPR005242; KEGG: gur:Gura_1653 hypothetical protein; PFAM: lysylphosphatidylglycerol synthetase/UPF0104; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein YP_004371279.1 InterPro IPR013429; KEGG: drt:Dret_0687 regulatory protein, FmdB family; PFAM: Regulatory protein, FmdB, SMART: Regulatory protein, FmdB, SPTR: Regulatory protein, FmdB family; TIGRFAM: Regulatory protein, FmdB, PFAM: Zinc ribbon domain; TIGRFAM: regulatory protein, FmdB family YP_004371280.1 COGs: COG0227 ribosomal protein L28; HAMAP: ribosomal protein L28; InterPro IPR001383; KEGG: dba:Dbac_0072 ribosomal protein L28; PFAM: ribosomal protein L28; SPTR: 50S ribosomal protein L28; TIGRFAM: ribosomal protein L28; PFAM: ribosomal L28 family; TIGRFAM: ribosomal protein L28 YP_004371281.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: adg:Adeg_1147 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: acyltransferase; PFAM: acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_004371282.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; HAMAP: UbiE/COQ5 methyltransferase; InterPro IPR004033; KEGG: dds:Ddes_1908 ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; SPTR: Ubiquinone/menaquinone biosynthesis methyltransferase; TIGRFAM: UbiE/COQ5 methyltransferase; PFAM: ubiE/COQ5 methyltransferase; TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferases YP_004371283.1 COGs: COG0190 5 10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; HAMAP: Tetrahydrofolate dehydrogenase/cyclohydrolase; InterPro IPR020630:IPR020631:IPR000672; KEGG: sat:SYN_02873 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; PRIAM: methenyltetrahydrofolate cyclohydrolase; SPTR: bifunctional protein folD; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain YP_004371284.1 KEGG: pai:PAE0506 paREP15, coiled-coil protein; SPTR: PaREP15, coiled-coil protein YP_004371285.1 COGs: COG1430 conserved hypothetical protein; InterPro IPR003795; KEGG: rbi:RB2501_10487 hypothetical protein; PFAM: protein of unknown function DUF192; SPTR: uncharacterized protein; PFAM: Uncharacterized ACR, COG1430 YP_004371286.1 InterPro IPR012312; KEGG: dol:Dole_0760 hemerythrin HHE cation binding domain-containing protein; PFAM: Haemerythrin/HHE cation-binding motif; SPTR: Hemerythrin HHE cation binding domain protein; PFAM: Hemerythrin HHE cation binding domain YP_004371287.1 InterPro IPR002641; KEGG: net:Neut_1317 patatin; PFAM: patatin/phospholipase A2-related; SPTR: patatin; PFAM: patatin-like phospholipase YP_004371288.1 KEGG: ptm:GSPATT00028557001 hypothetical protein; SPTR: Genome sequencing data, contig C321 YP_004371289.1 COGs: COG0196 FAD synthase; InterPro IPR015865:IPR015864:IPR002606; KEGG: sfu:Sfum_3182 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; riboflavin kinase; PRIAM: FAD synthetase., riboflavin kinase; SMART: riboflavin kinase; SPTR: riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin kinase/FAD synthetase; PFAM: riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase YP_004371290.1 HAMAP: ribosome maturation factor RimP; InterPro IPR003728; KEGG: gsu:GSU1585 hypothetical protein; PFAM: ribosome maturation factor RimP; SPTR: ribosome maturation factor rimP; PFAM: Uncharacterised BCR, YhbC family COG0779 YP_004371291.1 COGs: COG0195 transcription elongation factor; InterProIPR022967:IPR004087:IPR003583:IPR013735:IPR 003029:IPR010213; KEGG: dbr:Deba_0889 transcription termination factor NusA; PFAM: transcription factor NusA, N-terminal; ribosomal protein S1, RNA-binding domain; SMART: RNA-binding domain, S1; K Homology; Helix-hairpin-helix DNA-binding motif, class 1; SPTR: transcription termination factor NusA; TIGRFAM: transcription termination factor NusA; PFAM: NusA N-terminal domain; S1 RNA binding domain; TIGRFAM: transcription termination factor NusA YP_004371293.1 COGs: COG0532 translation initiation factor 2 (IF-2; GTPase); InterProIPR006847:IPR000795:IPR004161:IPR000178:IPR 005225; KEGG: sfu:Sfum_1228 translation initiation factor IF-2; PFAM: protein synthesis factor, GTP-binding; translation initiation factor IF-2, N-terminal; translation elongation factor EFTu/EF1A, domain 2; SPTR: translation initiation factor IF-2; TIGRFAM: translation initiation factor aIF-2, bacterial-like; Small GTP-binding protein; PFAM: Elongation factor Tu domain 2; translation-initiation factor 2; translation initiation factor IF-2, N-terminal region; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation initiation factor IF-2 YP_004371294.1 COGs: COG1550 conserved hypothetical protein; InterPro IPR007546; KEGG: dal:Dalk_4739 protein of unknown function DUF503; PFAM: protein of unknown function DUF503; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF503) YP_004371295.1 COGs: COG0858 ribosome-binding factor A; HAMAP: ribosome-binding factor A; InterPro IPR000238; KEGG: sat:SYN_01785 ribosome-binding factor A; PFAM: ribosome-binding factor A; SPTR: ribosome-binding factor A; TIGRFAM: ribosome-binding factor A; PFAM: ribosome-binding factor A; TIGRFAM: ribosome-binding factor A YP_004371296.1 COGs: COG0130 Pseudouridine synthase; HAMAP: tRNA pseudouridine synthase II, TruB; InterPro IPR002501:IPR014780; KEGG: gsu:GSU1591 tRNA pseudouridine synthase B; PFAM: Pseudouridine synthase II; SPTR: tRNA pseudouridine synthase B; TIGRFAM: tRNA pseudouridine synthase II, TruB; PFAM: TruB family pseudouridylate synthase (N terminal domain); TIGRFAM: tRNA pseudouridine 55 synthase YP_004371297.1 COGs: COG0184 ribosomal protein S15P/S13E; InterPro IPR000589:IPR005290; KEGG: mxa:MXAN_2072 30S ribosomal protein S15; PFAM: ribosomal protein S15; SPTR: 30S ribosomal protein S15; TIGRFAM: ribosomal protein S15, bacterial-type; PFAM: ribosomal protein S15; TIGRFAM: ribosomal protein S15, bacterial/organelle YP_004371298.1 COGs: COG1185 polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); HAMAP: polyribonucleotide nucleotidyltransferase; InterProIPR004087:IPR022967:IPR001247:IPR015847:IPR 015848:IPR018111:IPR003029:IPR012162; KEGG: gsu:GSU1593 polynucleotide phosphorylase/polyadenylase; PFAM: Exoribonuclease, phosphorolytic domain 1; Exoribonuclease, phosphorolytic domain 2; polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; K Homology, type 1, subgroup; ribosomal protein S1, RNA-binding domain; PRIAM: polyribonucleotide nucleotidyltransferase; SMART: RNA-binding domain, S1; K Homology; SPTR: polyribonucleotide nucleotidyltransferase; TIGRFAM: polyribonucleotide nucleotidyltransferase; PFAM: KH domain; S1 RNA binding domain; 3' exoribonuclease, domain 1; 3' exoribonuclease, domain 2; polyribonucleotide nucleotidyltransferase, RNA binding domain; TIGRFAM: polyribonucleotide nucleotidyltransferase YP_004371299.1 COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765:IPR007863; KEGG: dbr:Deba_0898 peptidase M16 domain protein; PFAM: peptidase M16, C-terminal; peptidase M16, N-terminal; PRIAM: processing peptidase; SPTR: peptidase M16 domain protein; PFAM: peptidase M16 inactive domain; Insulinase (peptidase M16) YP_004371300.1 COGs: COG1702 phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: sfu:Sfum_2163 PhoH family protein; PFAM: PhoH-like protein; SPTR: PhoH-like domain protein; PFAM: PhoH-like protein YP_004371301.1 COGs: COG1480 membrane-associated HD superfamily hydrolase; InterPro IPR003607:IPR011621:IPR006674:IPR006675; KEGG: sfu:Sfum_2164 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; Metal-dependent phosphohydrolase, 7TM intracellular domain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Metal dependent phosphohydrolase; TIGRFAM: Uncharacterised protein family HDIG; PFAM: 7TM-HD extracellular; HD domain; 7TM receptor with intracellular HD hydrolase; TIGRFAM: uncharacterized domain HDIG YP_004371302.1 COGs: COG0319 metal-dependent hydrolase; HAMAP: Uncharacterised protein family UPF0054, metalloprotease YbeY, predicted; InterPro IPR002036; KEGG: gur:Gura_1782 hypothetical protein; PFAM: Uncharacterised protein family UPF0054, metalloprotease YbeY, predicted; SPTR: metalloprotease GSU2284; TIGRFAM: Uncharacterised protein family UPF0054, metalloprotease YbeY, predicted; manually curated; PFAM: Uncharacterized protein family UPF0054; TIGRFAM: metalloprotein, YbeY/UPF0054 family YP_004371303.1 COGs: COG0854 Pyridoxal phosphate biosynthesis protein; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ; InterPro IPR004569; KEGG: gme:Gmet_1885 pyridoxine 5'-phosphate synthase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ; PRIAM: Pyridoxine 5'-phosphate synthase; SPTR: Pyridoxine 5'-phosphate synthase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ; PFAM: Pyridoxal phosphate biosynthesis protein PdxJ; TIGRFAM: pyridoxine 5'-phosphate synthase YP_004371304.1 KEGG: gme:Gmet_2813 hypothetical protein; SPTR: uncharacterized protein YP_004371305.1 InterPro IPR019734:IPR001440; KEGG: cyc:PCC7424_1361 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR-1; SPTR: Tetratricopeptide repeat family; PFAM: Tetratricopeptide repeat YP_004371306.1 COGs: COG0501 Zn-dependent protease with chaperone function; HAMAP: peptidase M48, protease HtpX, InterPro IPR001915:IPR022919; KEGG: dat:HRM2_22250 peptidase (M48 family protein); PFAM: peptidase M48; SPTR: Protease HtpX homolog; PFAM: peptidase M48 YP_004371307.1 KEGG: dal:Dalk_2528 hypothetical protein; SPTR: uncharacterized protein YP_004371308.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: gur:Gura_1422 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004371309.1 COGs: COG0095 Lipoate-protein ligase A; InterPro IPR004143; KEGG: sth:STH1918 lipoate protein ligase; PFAM: Biotin/lipoate A/B protein ligase; SPTR: lipoate protein ligase; manually curated; PFAM: Biotin/lipoate A/B protein ligase YP_004371310.1 COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; HAMAP: Phenylalanyl-tRNA synthetase alpha chain 1, bacterial; InterPro IPR004188:IPR002319:IPR004529:IPR022911; KEGG: dps:DP1424 phenylalanyl-tRNA synthetase, alpha chain; PFAM: Phenylalanyl-tRNA synthetase; Phenylalanyl-tRNA synthetase, class II, N-terminal; SPTR: Phenylalanyl-tRNA synthetase alpha chain; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit YP_004371311.1 COGs: COG0292 ribosomal protein L20; HAMAP: ribosomal protein L20; InterPro IPR005813; KEGG: dbr:Deba_0830 ribosomal protein L20; PFAM: ribosomal protein L20; SPTR: ribosomal protein L20; TIGRFAM: ribosomal protein L20; PFAM: ribosomal protein L20; TIGRFAM: ribosomal protein L20 YP_004371312.1 HAMAP: ribosomal protein L35, non-mitochondrial; InterPro IPR021137:IPR001706; KEGG: cno:NT01CX_1762 50S ribosomal protein L35; PFAM: ribosomal protein L35; SPTR: 50S ribosomal protein L35 2; TIGRFAM: ribosomal protein L35, non-mitochondrial; PFAM: ribosomal protein L35; TIGRFAM: ribosomal protein L35 YP_004371313.1 COGs: COG0290 translation initiation factor 3 (IF-3); HAMAP: translation initiation factor 3; InterPro IPR019814:IPR019815:IPR001288; KEGG: sfu:Sfum_0425 translation initiation factor IF-3; PFAM: translation initiation factor 3, C-terminal; translation initiation factor 3, N-terminal; SPTR: translation initiation factor IF-3; TIGRFAM: translation initiation factor 3; PFAM: translation initiation factor IF-3, C-terminal domain; translation initiation factor IF-3, N-terminal domain; TIGRFAM: translation initiation factor IF-3 YP_004371314.1 COGs: COG0441 Threonyl-tRNA synthetase; InterPro IPR012947:IPR002314:IPR004154:IPR002320; KEGG: sfu:Sfum_0424 threonyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Threonyl/alanyl tRNA synthetase, SAD; Anticodon-binding; SMART: Threonyl/alanyl tRNA synthetase, SAD; SPTR: Threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-tRNA synthetase YP_004371315.1 COGs: COG1720 conserved hypothetical protein; InterPro IPR001378; KEGG: alv:Alvin_3236 protein of unknown function UPF0066; PFAM: Uncharacterised protein family UPF0066; SPTR: uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0066; PFAM: Uncharacterised protein family UPF0066; TIGRFAM: methyltransferase, YaeB/AF_0241 family YP_004371316.1 COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594:IPR007901; KEGG: tpe:Tpen_1822 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; ThiF family YP_004371317.1 KEGG: chl:Chy400_2866 FHA domain containing protein; SPTR: uncharacterized protein YP_004371318.1 InterPro IPR003646; KEGG: cdl:CDR20291_0971 cell wall hydrolase; SMART: SH3-like domain, bacterial; SPTR: Probable cell wall hydrolase YP_004371319.1 COGs: COG1280 threonine efflux protein; InterPro IPR001123; KEGG: tjr:TherJR_2187 lysine exporter protein (LysE/YggA); PFAM: Lysine exporter protein (LYSE/YGGA); SPTR: Lysine exporter protein (LYSE/YGGA); PFAM: LysE type translocator YP_004371320.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279; KEGG: slp:Slip_0770 beta-lactamase-like protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Beta-lactamase-like protein; PFAM: Metallo-beta-lactamase superfamily YP_004371321.1 COGs: COG0452 phosphopantothenoylcysteine synthetase/decarboxylase; InterPro IPR003382:IPR007085:IPR005252; KEGG: pth:PTH_1793 phosphopantothenoylcysteine synthetase/decarboxylase; PFAM: DNA/pantothenate metabolism flavoprotein, C-terminal; Flavoprotein; PRIAM: phosphopantothenate--cysteine ligase; SPTR: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: DNA / pantothenate metabolism flavoprotein; Flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, prokaryotic YP_004371322.1 COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005122:IPR005273; KEGG: gur:Gura_2925 phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase-like; SPTR: Phage SPO1 DNA polymerase-related protein; TIGRFAM: Phage SPO1 DNA polymerase-related protein; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4 YP_004371323.1 COGs: COG1030 Membrane-bound serine protease (ClpP class); InterPro IPR002810; KEGG: sfu:Sfum_0465 hypothetical protein; PFAM: Nodulation efficiency, NfeD; SPTR: Nodulation efficiency protein NfeD; PFAM: NfeD-like YP_004371324.1 COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: dbr:Deba_1222 band 7 protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Band 7 protein; PFAM: SPFH domain / Band 7 family YP_004371325.1 InterPro IPR011112; KEGG: sfu:Sfum_0463 hypothetical protein; SMART: Rho termination factor, N-terminal; SPTR: uncharacterized protein YP_004371326.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR001763:IPR011637; KEGG: sfu:Sfum_1513 cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain; Uncharacterised protein family YphA; SMART: Cyclic nucleotide-binding domain; Rhodanese-like; SPTR: Cyclic nucleotide-binding protein; PFAM: methylamine utilisation protein MauE; Rhodanese-like domain; Cyclic nucleotide-binding domain YP_004371327.1 KEGG: sfu:Sfum_1515 hypothetical protein; SPTR: uncharacterized protein YP_004371328.1 KEGG: act:ACLA_027880 VHS domain protein; SPTR: nucleotide excision repair factor NEF2 RAD23 component YP_004371329.1 KEGG: dia:Dtpsy_2897 CheA signal transduction histidine kinase; SPTR: CheA signal transduction histidine kinase; PFAM: Response regulator receiver domain YP_004371330.1 COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR003593:IPR006345; KEGG: dma:DMR_18670 helicase RecD/TraA family protein; PRIAM: exodeoxyribonuclease V; SMART: ATPase, AAA+ type, core; SPTR: Helicase RecD/TraA family protein; TIGRFAM: DNA helicase, RecD/TraA type; PFAM: ATPase (DUF699); TIGRFAM: helicase, , RecD/TraA family YP_004371331.1 COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: cac:CA_C0229 Zn-dependent protease TldD; PFAM: peptidase U62, modulator of DNA gyrase; SPTR: peptidase U62 modulator of DNA gyrase; PFAM: modulator of DNA gyrase YP_004371333.1 COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: drt:Dret_2237 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: histidine triad (HIT) protein; PFAM: HIT domain YP_004371334.1 COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544; KEGG: sfu:Sfum_3708 aminotransferase, class IV; PFAM: Aminotransferase, class IV; SPTR: Aminotransferase, class IV; PFAM: Aminotransferase class IV YP_004371335.1 COGs: COG0205 6-phosphofructokinase; InterPro IPR000023; KEGG: sta:STHERM_c17480 pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; PFAM: phosphofructokinase domain; SPTR: Pyrophosphate-dependent phosphofructokinase; PFAM: phosphofructokinase; TIGRFAM: diphosphate--fructose-6-phosphate 1-phosphotransferase YP_004371336.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR013709:IPR000891:IPR005675; KEGG: sfu:Sfum_2174 alpha-isopropylmalate/homocitrate synthase transferase; PFAM: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; pyruvate carboxyltransferase; PRIAM: (R)-citramalate synthase; SMART: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; SPTR: 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase-related; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase YP_004371337.1 COGs: COG0527 aspartokinase; InterPro IPR001048:IPR002912:IPR005260:IPR001341; KEGG: pca:Pcar_1006 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; SPTR: aspartokinase; TIGRFAM: aspartate kinase domain; aspartate kinase, monofunctional class; PFAM: Amino acid kinase; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase YP_004371338.1 COGs: COG2003 DNA repair protein; InterPro IPR001405; KEGG: msl:Msil_2077 DNA repair protein RadC; PFAM: Uncharacterised protein family UPF0758; SPTR: DNA repair protein RadC; TIGRFAM: Uncharacterised protein family UPF0758; PFAM: protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc YP_004371339.1 COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR019734:IPR013105; KEGG: nde:NIDE1962 hypothetical protein; PFAM: Tetratricopeptide TPR2; SPTR: uncharacterized protein; PFAM: Tetratricopeptide repeat YP_004371340.1 KEGG: dal:Dalk_1809 FecR protein; SPTR: FecR protein; PFAM: FecR protein YP_004371341.1 COGs: COG1661 DNA-binding protein with PD1-like DNA-binding motif; KEGG: gme:Gmet_2807 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF296) YP_004371342.1 COGs: COG0648 Endonuclease IV; InterPro IPR001719:IPR012307; KEGG: sti:Sthe_1657 apurinic endonuclease Apn1; PFAM: Xylose isomerase, TIM barrel domain; PRIAM: Deoxyribonuclease IV (phage-T(4)-induced); SMART: Endodeoxyribonuclease IV; SPTR: Probable endonuclease 4; TIGRFAM: Endodeoxyribonuclease IV; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: apurinic endonuclease (APN1) YP_004371343.1 COGs: COG0795 permease; InterPro IPR005495; KEGG: dbr:Deba_1284 permease YjgP/YjgQ family protein; PFAM: Permease YjgP/YjgQ, predicted; SPTR: Permease YjgP/YjgQ family protein; PFAM: Predicted permease YjgP/YjgQ family YP_004371344.1 COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: dde:Dde_2058 histone-like DNA-binding protein; PFAM: histone-like bacterial DNA-binding protein; SMART: histone-like bacterial DNA-binding protein; SPTR: histone-like DNA-binding protein; PFAM: Bacterial DNA-binding protein YP_004371346.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423:IPR010131; KEGG: gme:Gmet_1666 RND efflux system, outer membrane lipoprotein, NodT; PFAM: Outer membrane efflux protein; SPTR: RND efflux system, outer membrane lipoprotein, NodT; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT; PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family YP_004371347.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: mca:MCA1361 HlyD family secretion protein; PFAM: Secretion protein HlyD; SPTR: HlyD family secretion protein; TIGRFAM: Secretion protein HlyD; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004371348.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036:IPR004764; KEGG: mca:MCA1360 hydrophobe/amphiphile efflux-1 (HAE1) family protein; PFAM: Acriflavin resistance protein; SPTR: Hydrophobe/amphiphile Efflux-1 (HAE1) family protein; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family YP_004371349.1 KEGG: mgm:Mmc1_2155 hypothetical protein; SPTR: uncharacterized protein YP_004371350.1 COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: rmr:Rmar_0989 heat shock protein HSP20; PFAM: Heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family YP_004371351.1 COGs: COG0466 ATP-dependent Lon protease; InterProIPR003111:IPR003593:IPR003959:IPR008269:IPR 004815; KEGG: dol:Dole_1099 ATP-dependent protease La; PFAM: peptidase S16, Lon C-terminal; ATPase, AAA-type, core; peptidase S16, lon N-terminal; PRIAM: Endopeptidase La; SMART: peptidase S16, lon N-terminal; ATPase, AAA+ type, core; SPTR: Lon protease; TIGRFAM: peptidase S16, ATP-dependent protease La; PFAM: ATP-dependent protease La (LON) domain; ATPase associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La YP_004371352.1 COGs: COG0736 phosphopantetheinyl transferase (holo-ACP synthase); HAMAP: Holo-[acyl carrier protein] synthase; InterPro IPR008278:IPR002582:IPR004568; KEGG: has:Halsa_1878 holo-acyl-carrier-protein synthase; PFAM: 4'-phosphopantetheinyl transferase; SPTR: Holo-[acyl-carrier-protein] synthase; TIGRFAM: phosphopantethiene-protein transferase; Holo-[acyl carrier protein] synthase; PFAM: 4'-phosphopantetheinyl transferase superfamily; TIGRFAM: phosphopantethiene--protein transferase domain; holo-[acyl-carrier-protein] synthase YP_004371353.1 COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: gsu:GSU0385 NADH dehydrogenase subunit; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NADH dehydrogenase subunit, ; PFAM: NAD dependent epimerase/dehydratase YP_004371354.1 COGs: COG0533 Metal-dependent protease with possible chaperone activity; HAMAP: peptidase M22, O-sialoglycoprotein peptidase; InterPro IPR000905:IPR022450:IPR017861; KEGG: dbr:Deba_0941 metalloendopeptidase, glycoprotease; PFAM: peptidase M22, glycoprotease; PRIAM: O-sialoglycoprotein endopeptidase; SPTR: Probable O-sialoglycoprotein endopeptidase; TIGRFAM: peptidase M22, O-sialoglycoprotein peptidase; peptidase M22, glycoprotease, subgroup; PFAM: glycoprotease; TIGRFAM: glycoprotease GCP; metallohydrolase, glycoprotease/Kae1 family YP_004371355.1 COGs: COG1381 Recombinational DNA repair protein (RecF pathway); HAMAP: Recombination protein O, RecO; InterPro IPR003717; KEGG: sat:SYN_01535 DNA repair protein; PFAM: Recombination protein O, RecO; SPTR: DNA repair protein recO; TIGRFAM: Recombination protein O, RecO; PFAM: Recombination protein O C terminal; Recombination protein O N terminal; TIGRFAM: DNA repair protein RecO YP_004371356.1 COGs: COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family; KEGG: rca:Rcas_0469 glycosyltransferase; SPTR: 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family-like protein YP_004371357.1 COGs: COG2840 conserved hypothetical protein; InterPro IPR002625; KEGG: acp:A2cp1_4083 Smr protein/MutS2; PFAM: Smr protein/MutS2 C-terminal; SMART: Smr protein/MutS2 C-terminal; SPTR: Smr protein/MutS2; PFAM: Smr domain YP_004371358.1 COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: sfu:Sfum_3753 peptidase U32; PFAM: peptidase U32; SPTR: peptidase U32; PFAM: peptidase U32 YP_004371359.1 SPTR: phosphatidylglycerophosphatase A YP_004371360.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; HAMAP: Chaperone DnaJ; InterPro IPR001623:IPR001305:IPR002939:IPR012724; KEGG: sfu:Sfum_1756 chaperone protein DnaJ; PFAM: Chaperone DnaJ, C-terminal; Heat shock protein DnaJ, N-terminal; Heat shock protein DnaJ, cysteine-rich domain; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Chaperone protein dnaJ; TIGRFAM: Chaperone DnaJ; PFAM: DnaJ C terminal region; DnaJ central domain (4 repeats); DnaJ domain; TIGRFAM: chaperone protein DnaJ YP_004371361.1 COGs: COG0011 conserved hypothetical protein; InterPro IPR002767; KEGG: dau:Daud_2069 hypothetical protein; PFAM: protein of unknown function DUF77; SPTR: uncharacterized protein; TIGRFAM: protein of unknown function DUF77; PFAM: Domain of unknown function DUF77; TIGRFAM: uncharacterized protein, MTH1187 family YP_004371362.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: tye:THEYE_A1490 response regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator; PFAM: Response regulator receiver domain YP_004371363.1 KEGG: abu:Abu_1088 cytochrome bd oxidase, subunit II; SPTR: Cytochrome bd oxidase, subunit II YP_004371364.1 InterPro IPR002781; KEGG: sfu:Sfum_0626 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004371365.1 COGs: COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; InterPro IPR003382:IPR004507; KEGG: gme:Gmet_2105 3-octaprenyl-4hydroxybenzoate decarboxylase; PFAM: Flavoprotein; SPTR: 3-octaprenyl-4hydroxybenzoate decarboxylase; TIGRFAM: Phenylacrylic acid decarboxylase; PFAM: Flavoprotein; TIGRFAM: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases YP_004371366.1 COGs: COG3216 conserved hypothetical protein; InterPro IPR018639; KEGG: sat:SYN_00422 hypothetical protein; PFAM: protein of unknown function DUF2062; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2062) YP_004371367.1 COGs: COG0030 Dimethyladenosine transferase (rRNA methylation); HAMAP: ribosomal RNA adenine dimethylase; InterPro IPR020598:IPR001737:IPR011530; KEGG: dal:Dalk_3122 dimethyladenosine transferase; PFAM: ribosomal RNA adenine methylase transferase; SMART: ribosomal RNA adenine methylase transferase, N-terminal; SPTR: ribosomal RNA small subunit methyltransferase A; TIGRFAM: ribosomal RNA adenine dimethylase; PFAM: ribosomal RNA adenine dimethylase; TIGRFAM: dimethyladenosine transferase YP_004371368.1 COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: sfu:Sfum_1307 peptidase M28; PFAM: peptidase M28; SPTR: peptidase M28; PFAM: peptidase M28 YP_004371369.1 InterPro IPR005358; KEGG: sfu:Sfum_2545 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0153) YP_004371370.1 COGs: COG5616 integral membrane protein; KEGG: rlg:Rleg_2399 hypothetical protein; PRIAM: adenylate cyclase; SPTR: transmembrane adenylate cyclase YP_004371371.1 KEGG: rhi:NGR_b05020 hypothetical protein; SPTR: uncharacterized protein YP_004371372.1 KEGG: ipo:Ilyop_0783 arsenical-resistance protein; SPTR: Major facilitator superfamily protein YP_004371373.1 COGs: COG0767 ABC-type transport system involved in resistance to organic solvents permease component; InterPro IPR003453; KEGG: sat:SYN_02070 ABC transporter permease; PFAM: Domain of unknown function DUF140; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein YP_004371374.1 COGs: COG1127 ABC-type transport system involved in resistance to organic solvents ATPase component; InterPro IPR003593:IPR003439; KEGG: dvm:DvMF_0039 ABC transporter related; PFAM: ABC transporter-like; PRIAM: sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter YP_004371375.1 COGs: COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: sfu:Sfum_2416 hypothetical protein; PFAM: Mammalian cell entry-related; SPTR: Mammalian cell entry related domain protein; PFAM: mce related protein YP_004371376.1 COGs: COG3009 conserved hypothetical protein; InterPro IPR005586; KEGG: mca:MCA0364 lipoprotein; PFAM: protein of unknown function DUF330; SPTR: lipoprotein; PFAM: protein of unknown function (DUF330) YP_004371377.1 COGs: COG1719 hydrocarbon binding protein (contains V4R domain); InterPro IPR004096; KEGG: dma:DMR_41680 hypothetical protein; PFAM: 4-vinyl reductase, 4VR; SPTR: uncharacterized protein; PFAM: V4R domain YP_004371378.1 COGs: COG2114 adenylate cyclase 3 (some protein contain HAMP domain); InterPro IPR001054; KEGG: npu:Npun_R0352 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: adenylate/guanylate cyclase; PFAM: adenylate and Guanylate cyclase catalytic domain YP_004371379.1 KEGG: sfu:Sfum_0673 hypothetical protein; SPTR: uncharacterized protein YP_004371380.1 KEGG: ecn:Ecaj_0020 conjugation TrbI-like protein; SPTR: Conjugation TrbI-like protein YP_004371381.1 COGs: COG0366 glycosidase; InterPro IPR006589:IPR006047; KEGG: mem:Memar_0386 alpha amylase, catalytic region; PFAM: glycosyl hydrolase, family 13, catalytic domain; SMART: glycosyl hydrolase, family 13, subfamily, catalytic domain; SPTR: Alpha amylase catalytic region; PFAM: Alpha amylase, catalytic domain YP_004371382.1 KEGG: sfu:Sfum_1008 hypothetical protein; SPTR: uncharacterized protein YP_004371383.1 KEGG: cps:CPS_3226 hypothetical protein; SPTR: uncharacterized protein YP_004371384.1 COGs: COG0387 Ca2+/H+ antiporter; InterPro IPR004837:IPR004798; KEGG: sus:Acid_4937 calcium/cation antiporter; PFAM: Sodium/calcium exchanger membrane region; SPTR: Calcium/proton antiporter, CaCA family; TIGRFAM: Calcium/proton exchanger superfamily; PFAM: Sodium/calcium exchanger protein; TIGRFAM: calcium/proton exchanger; calcium/proton exchanger (cax) YP_004371385.1 InterPro IPR013099; KEGG: ppd:Ppro_0413 ion transport 2 domain-containing protein; PFAM: Ion transport 2; SPTR: Ion transport 2 domain protein; PFAM: Ion channel YP_004371386.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: sat:SYN_02948 acriflavin resistance periplasmic protein; PFAM: Secretion protein HlyD; SPTR: Acriflavin resistance periplasmic protein; TIGRFAM: Secretion protein HlyD; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004371387.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036:IPR004764; KEGG: sfu:Sfum_1457 hydrophobe/amphiphile efflux-1 (HAE1) family protein; PFAM: Acriflavin resistance protein; SPTR: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family YP_004371388.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423:IPR010131; KEGG: aba:Acid345_4072 RND efflux system, outer membrane lipoprotein, NodT; PFAM: Outer membrane efflux protein; SPTR: RND efflux system, outer membrane lipoprotein, NodT; TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT; PFAM: Outer membrane efflux protein; TIGRFAM: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family YP_004371389.1 COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR003661:IPR003594; KEGG: dma:DMR_16190 two-component sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004371390.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: sfu:Sfum_0643 two component, sigma54 specific, fis family transcriptional regulator; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; TIGRFAM: nitrogen regulation protein NR(I) YP_004371391.1 InterPro IPR001789; KEGG: sfu:Sfum_0647 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain YP_004371392.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279:IPR001763; KEGG: dsa:Desal_2679 beta-lactamase domain protein; PFAM: Beta-lactamase-like; Rhodanese-like; SMART: Beta-lactamase-like; Rhodanese-like; SPTR: Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain YP_004371393.1 COGs: COG0480 translation elongation factors (GTPase); InterProIPR005517:IPR000640:IPR000795:IPR004161:IPR 004540:IPR005225; KEGG: sat:SYN_02930 elongation factor G; PFAM: protein synthesis factor, GTP-binding; translation elongation factor EFTu/EF1A, domain 2; translation elongation factor EFG/EF2, domain IV; translation elongation factor EFG/EF2, C-terminal; SMART: translation elongation factor EFG/EF2, domain IV; translation elongation factor EFG/EF2, C-terminal; SPTR: Elongation factor G 2; TIGRFAM: translation elongation factor EFG/EF2; Small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain YP_004371394.1 COGs: COG2258 conserved hypothetical protein; InterPro IPR005302; KEGG: dau:Daud_1892 MOSC domain-containing protein; PFAM: Molybdenum cofactor sulfurase, C-terminal; SPTR: MOSC domain containing protein; PFAM: MOSC domain YP_004371395.1 COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR001453:IPR020817; KEGG: chy:CHY_0805 molybdenum cofactor synthesis domain-containing protein; PFAM: Molybdopterin binding; SMART: Molybdopterin binding; SPTR: Molybdenum cofactor synthesis domain protein; TIGRFAM: Molybdenum cofactor synthesis; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain YP_004371396.1 COGs: COG0574 phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279:IPR000121:IPR006319; KEGG: dak:DaAHT2_0891 phosphoenolpyruvate synthase; PFAM: pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme; PRIAM: pyruvate, water dikinase; SPTR: phosphoenolpyruvate synthase; TIGRFAM: phosphoenolpyruvate synthase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: phosphoenolpyruvate synthase YP_004371397.1 COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterProIPR003607:IPR007685:IPR006674:IPR004095:IPR 002912:IPR004811; KEGG: gsu:GSU2236 GTP pyrophosphokinase; PFAM: RelA/SpoT; Metal-dependent phosphohydrolase, HD subdomain; TGS; Amino acid-binding ACT; PRIAM: GTP diphosphokinase; SMART: RelA/SpoT; Metal-dependent phosphohydrolase, HD domain; SPTR: GTP pyrophosphokinase; TIGRFAM: RelA/SpoT protein; PFAM: HD domain; ACT domain; TGS domain; Region found in RelA / SpoT proteins; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family YP_004371398.1 COGs: COG0442 Prolyl-tRNA synthetase; HAMAP: Prolyl-tRNA synthetase, class IIa, bacterial; InterPro IPR002314:IPR007214:IPR004154:IPR004500; KEGG: dak:DaAHT2_0252 prolyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; YbaK/aminoacyl-tRNA synthetase-associated domain; Anticodon-binding; SPTR: Prolyl-tRNA synthetase; TIGRFAM: Prolyl-tRNA synthetase, class IIa, bacterial; PFAM: YbaK / prolyl-tRNA synthetases associated domain; Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: prolyl-tRNA synthetase, family II YP_004371399.1 COGs: COG3359 exonuclease; KEGG: mac:MA0820 hypothetical protein; SPTR: uncharacterized protein YP_004371400.1 InterPro IPR022265; KEGG: dat:HRM2_13290 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP03790; TIGRFAM: TIGR03790 family protein YP_004371401.1 KEGG: gme:Gmet_0753 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2905) YP_004371402.1 COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: gbm:Gbem_0684 methylmalonyl-CoA decarboxylase; PFAM: Crotonase, core; PRIAM: methylmalonyl-CoA decarboxylase; SPTR: methylmalonyl-CoA decarboxylase; PFAM: Enoyl-CoA hydratase/isomerase YP_004371403.1 COGs: COG0863 DNA modification methylase; InterPro IPR002941; KEGG: tye:THEYE_A0518 modification methylase MjaI; PFAM: DNA methylase N-4/N-6; SPTR: Modification methylase MjaI; PFAM: DNA methylase YP_004371404.1 KEGG: dhd:Dhaf_4485 hypothetical protein; SPTR: uncharacterized protein YP_004371405.1 InterPro IPR013406; KEGG: cyn:Cyan7425_1443 addiction module component, TIGR02574 family; PFAM: Addiction module component, CHP02574; SPTR: uncharacterized protein; TIGRFAM: Addiction module component, CHP02574; PFAM: addiction module component; TIGRFAM: addiction module component, TIGR02574 family YP_004371406.1 KEGG: dat:HRM2_p00530 hypothetical protein; SPTR: Predicted plasmid stabilisation protein ParE YP_004371407.1 COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); HAMAP: NAD-dependent DNA ligase; InterProIPR013840:IPR003583:IPR001357:IPR013839:IPR 004150:IPR004149:IPR000445:IPR001679; KEGG: sat:SYN_02935 NAD-dependent DNA ligase; PFAM: NAD-dependent DNA ligase, adenylation; NAD-dependent DNA ligase, OB-fold; Zinc-finger, NAD-dependent DNA ligase C4-type; Helix-hairpin-helix motif; BRCT; PRIAM: DNA ligase (NAD(+)); SMART: NAD-dependent DNA ligase, N-terminal; Helix-hairpin-helix DNA-binding motif, class 1; BRCT; SPTR: DNA ligase; TIGRFAM: NAD-dependent DNA ligase; PFAM: NAD-dependent DNA ligase OB-fold domain; NAD-dependent DNA ligase adenylation domain; NAD-dependent DNA ligase C4 zinc finger domain; Helix-hairpin-helix motif; BRCA1 C Terminus (BRCT) domain; TIGRFAM: DNA ligase, NAD-dependent YP_004371408.1 COGs: COG1254 acylphosphatase; HAMAP: acylphosphatase; InterPro IPR001792; KEGG: rxy:Rxyl_0794 acylphosphatase; PFAM: acylphosphatase-like; SPTR: acylphosphatase; PFAM: acylphosphatase YP_004371409.1 KEGG: dbr:Deba_3150 hypothetical protein; SPTR: uncharacterized protein YP_004371410.1 KEGG: drt:Dret_1951 MJ0042 family finger-like protein; SPTR: MJ0042 family finger-like protein; PFAM: Yip1 domain YP_004371411.1 KEGG: btr:Btr_2504 cell division transmembrane protein FtsK; SPTR: Cell division transmembrane protein FtsK; PFAM: protein of unknown function (DUF1049) YP_004371412.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dak:DaAHT2_1706 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain YP_004371413.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003661:IPR003594; KEGG: dbr:Deba_2636 GAF sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SPTR: GAF sensor signal transduction histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain YP_004371414.1 COGs: COG0297 glycogen synthase; HAMAP: glycogen/starch synthases, ADP-glucose type; InterPro IPR013534:IPR001296:IPR011835; KEGG: dbr:Deba_2637 glycogen/starch synthase, ADP-glucose type; PFAM: Starch synthase, catalytic domain; glycosyl transferase, group 1; PRIAM: Starch synthase; SPTR: glycogen/starch synthase, ADP-glucose type; TIGRFAM: glycogen/starch synthases, ADP-glucose type; PFAM: Starch synthase catalytic domain; glycosyl transferases group 1; TIGRFAM: glycogen/starch synthases, ADP-glucose type YP_004371415.1 COGs: COG1085 Galactose-1-phosphate uridylyltransferase; InterPro IPR005850:IPR001937; KEGG: dak:DaAHT2_1705 galactose-1-phosphate uridylyltransferase; PFAM: Galactose-1-phosphate uridyl transferase, C-terminal; PRIAM: UDP-glucose--hexose-1-phosphate uridylyltransferase; SPTR: Galactose-1-phosphate uridylyltransferase; TIGRFAM: Galactose-1-phosphate uridyl transferase, class I; PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 1 YP_004371416.1 COGs: COG2834 Outer membrane lipoprotein-sorting protein; InterPro IPR004564; KEGG: sat:SYN_00884 outer membrane lipoprotein carrier protein; PFAM: Outer membrane lipoprotein carrier protein LolA; SPTR: Outer membrane lipoprotein carrier protein LolA; PFAM: Outer membrane lipoprotein carrier protein LolA YP_004371417.1 COGs: COG0379 Quinolinate synthase; InterPro IPR003473; KEGG: dal:Dalk_3894 quinolinate synthetase complex, A subunit; PFAM: Quinolinate synthetase A; PRIAM: Quinolinate synthase; SPTR: Quinolinate synthetase complex, A subunit; TIGRFAM: Quinolinate synthetase A; PFAM: Quinolinate synthetase A protein; TIGRFAM: quinolinate synthetase complex, A subunit YP_004371418.1 KEGG: chu:CHU_0223 sensor histidine kinase; SPTR: Sensor histidine kinase YP_004371419.1 COGs: COG4866 conserved hypothetical protein; KEGG: dbr:Deba_3070 uncharacterized conserved protein UCP018688; SPTR: Uncharacterized conserved protein UCP018688; PFAM: Uncharacterized conserved protein (DUF2156) YP_004371420.1 KEGG: chy:CHY_0797 hypothetical protein; SPTR: uncharacterized protein YP_004371421.1 COGs: COG0731 Fe-S oxidoreductase; InterPro IPR007197; KEGG: mem:Memar_1142 radical SAM domain-containing protein; PFAM: Radical SAM; SPTR: radical SAM protein; PFAM: Radical SAM superfamily YP_004371422.1 COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR002731:IPR018709:IPR008275; KEGG: tye:THEYE_A0388 (R)-2-hydroxyglutaryl-CoA dehydratase activator-related protein; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; protein of unknown function DUF2229, CoA enzyme activase; SPTR: uncharacterized protein; TIGRFAM: CoA enzyme activase; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase; CoA enzyme activase uncharacterised domain (DUF2229); TIGRFAM: CoA-substrate-specific enzyme activase YP_004371423.1 KEGG: cph:Cpha266_2146 hypothetical protein; SPTR: uncharacterized protein YP_004371424.1 KEGG: cak:Caul_4070 hypothetical protein; SPTR: uncharacterized protein YP_004371425.1 COGs: COG0309 Hydrogenase maturation factor; InterPro IPR000728:IPR010918:IPR011854; KEGG: rme:Rmet_1540 hydrogenase expression/formation protein HypE; PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; SPTR: uncharacterized protein; TIGRFAM: Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE YP_004371426.1 InterPro IPR005358; KEGG: tye:THEYE_A0135 lipoprotein, PFAM: Uncharacterised protein family UPF0153; SPTR: Lipoprotein, ; PFAM: Uncharacterised protein family (UPF0153) YP_004371427.1 KEGG: gym:GYMC10_5219 hypothetical protein; SPTR: uncharacterized protein YP_004371428.1 KEGG: dal:Dalk_4319 hypothetical protein; SPTR: uncharacterized protein YP_004371429.1 COGs: COG0436 aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: glo:Glov_1768 aminotransferase class I and II; PFAM: Aminotransferase, class I/classII; PRIAM: aspartate transaminase; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II YP_004371430.1 COGs: COG0061 sugar kinase; HAMAP: Inorganic polyphosphate/ATP-NAD kinase, predicted; InterPro IPR002504; KEGG: gsu:GSU2065 ATP-NAD kinase; PFAM: Inorganic polyphosphate/ATP-NAD kinase, predicted; PRIAM: NAD(+) kinase; SPTR: Probable inorganic polyphosphate/ATP-NAD kinase; PFAM: ATP-NAD kinase YP_004371431.1 COGs: COG1526 Uncharacterized protein required for formate dehydrogenase activity; HAMAP: formate dehydrogenase, subunit FdhD; InterPro IPR003786; KEGG: rer:RER_38060 formate dehydrogenase accessory protein; PFAM: formate dehydrogenase, subunit FdhD; SPTR: protein fdhD homolog; TIGRFAM: formate dehydrogenase, subunit FdhD; PFAM: FdhD/NarQ family; TIGRFAM: formate dehydrogenase accessory protein FdhD YP_004371432.1 InterPro IPR013217; KEGG: kfl:Kfla_2724 methyltransferase type 11; PFAM: methyltransferase type 12; SPTR: uncharacterized protein; PFAM: methyltransferase domain YP_004371433.1 COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR003660:IPR003661:IPR003594:IPR004010; KEGG: sfu:Sfum_3269 sensor protein; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; Cache; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Cache sensor signal transduction histidine kinase; PFAM: HAMP domain; Cache domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004371434.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: sfu:Sfum_3268 two component, sigma54 specific, fis family transcriptional regulator; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004371435.1 COGs: COG2189 adenine specific DNA methylase Mod; InterPro IPR002941; KEGG: tel:tll1482 adenine specific DNA methylase; PFAM: DNA methylase N-4/N-6; SPTR: Site-specific DNA-methyltransferase (adenine-specific); PFAM: DNA methylase YP_004371436.1 KEGG: dba:Dbac_0440 hypothetical protein; SPTR: uncharacterized protein YP_004371437.1 COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR006935; KEGG: tel:tll1480 type III restriction-modification enzyme helicase subunit; PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; SPTR: Type III restriction-modification enzyme helicase subunit; PFAM: Type III restriction enzyme, res subunit YP_004371438.1 KEGG: sfu:Sfum_3267 hypothetical protein; SPTR: uncharacterized protein YP_004371439.1 KEGG: sfu:Sfum_3266 hypothetical protein; SPTR: uncharacterized protein YP_004371440.1 COGs: COG0334 glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006096:IPR006097; KEGG: sfu:Sfum_3265 Glu/Leu/Phe/Val dehydrogenase, C terminal; PFAM: glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain; PRIAM: glutamate dehydrogenase (NAD(P)(+)); SMART: glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; SPTR: glutamate dehydrogenase (NAD/NADP); PFAM: glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain YP_004371441.1 COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: sat:SYN_00180 HflC protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Bacterial HflC protein; PFAM: SPFH domain / Band 7 family YP_004371442.1 COGs: COG0574 phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192; KEGG: sfu:Sfum_3264 phosphoenolpyruvate synthase; PFAM: pyruvate phosphate dikinase, PEP/pyruvate-binding; SPTR: phosphoenolpyruvate synthase; PFAM: pyruvate phosphate dikinase, PEP/pyruvate binding domain YP_004371443.1 COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR020843:IPR013154:IPR013149:IPR014187; KEGG: adg:Adeg_1192 zinc-binding alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, C-terminal; PRIAM: Alcohol dehydrogenase; SMART: polyketide synthase, enoylreductase; SPTR: Zinc-binding alcohol dehydrogenase; TIGRFAM: Alcohol dehydrogenase, zinc-binding type 2; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: zinc-binding alcohol dehydrogenase YP_004371444.1 COGs: COG0427 Acetyl-CoA hydrolase; KEGG: dhd:Dhaf_2858 acetyl-CoA hydrolase/transferase; SPTR: uncharacterized protein YP_004371445.1 COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537; KEGG: tte:TTE2481 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 14-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase YP_004371446.1 COGs: COG0465 ATP-dependent Zn protease; InterProIPR003593:IPR011546:IPR003959:IPR000642:IPR 005936; KEGG: sfu:Sfum_3197 ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; ATPase, AAA-type, core; peptidase M41, FtsH extracellular; PRIAM: Microtubule-severing ATPase; SMART: ATPase, AAA+ type, core; SPTR: Cell division protein ftsH homolog (ATP-dependent zinc-metallo protease); TIGRFAM: peptidase M41, FtsH; PFAM: peptidase M41; ATPase associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH YP_004371447.1 InterPro IPR011701; KEGG: chu:CHU_0395 permease; PFAM: Major facilitator superfamily MFS-1; SPTR: Permease; PFAM: Bacterial protein of unknown function (DUF894) YP_004371448.1 COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR003593:IPR003959:IPR012763; KEGG: sfu:Sfum_2789 DNA polymerase III, subunits gamma and tau; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: DNA polymerase III, subunits gamma and tau; TIGRFAM: DNA polymerase III, subunit gamma/ tau; PFAM: ATPase associated with various cellular activities (AAA); DNA polymerase III subunits gamma and tau domain III; TIGRFAM: DNA polymerase III, delta' subunit; DNA polymerase III, subunit gamma and tau YP_004371449.1 COGs: COG0718 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0133; InterPro IPR004401; KEGG: dal:Dalk_1999 hypothetical protein; PFAM: Uncharacterised protein family UPF0133; SPTR: UPF0133 protein Dred_0043; TIGRFAM: Uncharacterised protein family UPF0133; PFAM: Uncharacterised BCR, YbaB family COG0718; TIGRFAM: DNA-binding protein, YbaB/EbfC family YP_004371450.1 COGs: COG0353 Recombinational DNA repair protein (RecF pathway); HAMAP: RecR protein; InterPro IPR006171:IPR015967:IPR000093; KEGG: sfu:Sfum_2791 recombination protein RecR; PFAM: Toprim domain; Zinc finger C4-type, RecR; SMART: Toprim domain; SPTR: Recombination protein recR; TIGRFAM: RecR protein; PFAM: Toprim domain; RecR protein; TIGRFAM: recombination protein RecR YP_004371451.1 KEGG: mac:MA1938 hypothetical protein; SPTR: Predicted protein YP_004371452.1 InterPro IPR007712; KEGG: ttj:TTHC013 toxin-like protein; PFAM: Plasmid stabilisation system; SPTR: Toxin-like protein; PFAM: Plasmid stabilisation system protein YP_004371453.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182:IPR011923; KEGG: geo:Geob_3476 rod shape-determining protein RodA; PFAM: Cell cycle protein; SPTR: Rod shape-determining protein RodA; TIGRFAM: Rod shape-determining protein RodA; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA YP_004371454.1 InterPro IPR002146; KEGG: dbr:Deba_0283 H+transporting two-sector ATPase B/B' subunit; PFAM: ATPase, F0 complex, subunit B/B', bacterial/chloroplast; SPTR: H+transporting two-sector ATPase B/B' subunit; PFAM: ATP synthase B/B' CF(0) YP_004371455.1 COGs: COG0711 F0F1-type ATP synthase subunit b; HAMAP: ATPase, F0 complex, subunit B/B', bacterial/chloroplast; InterPro IPR002146:IPR005864; KEGG: drt:Dret_2216 ATP synthase F0, B subunit; PFAM: ATPase, F0 complex, subunit B/B', bacterial/chloroplast; SPTR: ATP synthase subunit b; TIGRFAM: ATPase, F0 complex, subunit B, bacterial; PFAM: ATP synthase B/B' CF(0); TIGRFAM: ATP synthase, F0 subunit b YP_004371456.1 COGs: COG0712 F0F1-type ATP synthase delta subunit (mitochondrial oligomycin sensitivity protein); HAMAP: ATPase, F1 complex, OSCP/delta subunit; InterPro IPR000711; KEGG: dol:Dole_0600 F0F1 ATP synthase subunit delta; PFAM: ATPase, F1 complex, OSCP/delta subunit; SPTR: ATP synthase subunit delta; TIGRFAM: ATPase, F1 complex, OSCP/delta subunit; PFAM: ATP synthase delta (OSCP) subunit; TIGRFAM: ATP synthase, F1 delta subunit YP_004371457.1 COGs: COG0056 F0F1-type ATP synthase alpha subunit; HAMAP: ATPase, F1 complex, alpha subunit; InterPro IPR004100:IPR000194:IPR000793:IPR005294; KEGG: sfu:Sfum_2584 F0F1 ATP synthase subunit alpha; PFAM: ATPase, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal; SPTR: ATP synthase subunit alpha; TIGRFAM: ATPase, F1 complex, alpha subunit; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: proton translocating ATP synthase, F1 alpha subunit YP_004371458.1 COGs: COG0224 F0F1-type ATP synthase gamma subunit; HAMAP: ATPase, F1 complex, gamma subunit; InterPro IPR000131; KEGG: dbr:Deba_0287 ATP synthase F1, gamma subunit; PFAM: ATPase, F1 complex, gamma subunit; SPTR: ATP synthase subunit gamma; TIGRFAM: ATPase, F1 complex, gamma subunit; PFAM: ATP synthase; TIGRFAM: ATP synthase, F1 gamma subunit YP_004371459.1 COGs: COG0055 F0F1-type ATP synthase beta subunit; HAMAP: ATPase, F1 complex, beta subunit; InterProIPR003593:IPR004100:IPR000194:IPR000793:IPR 005722; KEGG: sat:SYN_00544 F0F1 ATP synthase subunit beta; PFAM: ATPase, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP synthase subunit beta; TIGRFAM: ATPase, F1 complex, beta subunit; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATP synthase, F1 beta subunit YP_004371460.1 COGs: COG0355 F0F1-type ATP synthase epsilon subunit (mitochondrial delta subunit); HAMAP: ATPase, F1 complex, delta/epsilon subunit; InterPro IPR020546:IPR020547:IPR001469; KEGG: dvm:DvMF_2832 F0F1 ATP synthase subunit epsilon; PFAM: ATPase, F1 complex, delta/epsilon subunit, N-terminal; ATPase, F1 complex, delta/epsilon subunit, C-terminal; SPTR: ATP synthase subunit epsilon; TIGRFAM: ATPase, F1 complex, delta/epsilon subunit; PFAM: ATP synthase, Delta/Epsilon chain, beta-sandwich domain; ATP synthase, Delta/Epsilon chain, long alpha-helix domain; TIGRFAM: ATP synthase, F1 epsilon subunit (delta in mitochondria) YP_004371461.1 COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR001242:IPR000873:IPR006163:IPR001031:IPR 010071; KEGG: mar:MAE_60000 McnE protein; PFAM: AMP-dependent synthetase/ligase; Condensation domain; phosphopantetheine-binding; Thioesterase; SPTR: OciC; TIGRFAM: Amino acid adenylation; PFAM: Thioesterase domain; phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain YP_004371462.1 COGs: COG2091 phosphopantetheinyl transferase; InterPro IPR008278; KEGG: npu:Npun_R2089 4'-phosphopantetheinyl transferase; PFAM: 4'-phosphopantetheinyl transferase; SPTR: 4'-phosphopantetheinyl transferase superfamily; PFAM: 4'-phosphopantetheinyl transferase superfamily YP_004371463.1 COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); HAMAP: bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase; InterPro IPR005835:IPR001451:IPR005882; KEGG: glo:Glov_0702 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; PFAM: nucleotidyl transferase; Bacterial transferase hexapeptide repeat; PRIAM: glucosamine-1-phosphate N-acetyltransferase; SPTR: bifunctional protein glmU; TIGRFAM: bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase; PFAM: nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase YP_004371464.1 COGs: COG0449 glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; HAMAP: glucosamine-fructose-6-phosphate aminotransferase, isomerising; InterPro IPR000583:IPR001347:IPR005855; KEGG: pca:Pcar_2933 glucosamine--fructose-6-phosphate aminotransferase; PFAM: glutamine amidotransferase, class-II; Sugar isomerase (SIS); PRIAM: glutamine--fructose-6-phosphate transaminase (isomerizing); SPTR: glutamine--fructose-6-phosphate transaminase; TIGRFAM: glucosamine-fructose-6-phosphate aminotransferase, isomerising; PFAM: SIS domain; glutamine amidotransferases class-II; TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase (isomerizing) YP_004371465.1 COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: dol:Dole_0143 amidohydrolase 2; PFAM: Amidohydrolase 2; SPTR: uncharacterized protein; PFAM: Amidohydrolase YP_004371466.1 COGs: COG2840 conserved hypothetical protein; InterPro IPR002625; KEGG: sfu:Sfum_0798 Smr protein/MutS2; PFAM: Smr protein/MutS2 C-terminal; SMART: Smr protein/MutS2 C-terminal; SPTR: Smr protein/MutS2; PFAM: Smr domain YP_004371467.1 COGs: COG1376 conserved hypothetical protein; InterPro IPR005490; KEGG: sfu:Sfum_0476 ErfK/YbiS/YcfS/YnhG family protein; PFAM: YkuD domain; SPTR: ErfK/YbiS/YcfS/YnhG family protein; PFAM: L,D-transpeptidase catalytic domain YP_004371468.1 KEGG: fbc:FB2170_05620 ATP synthase F0, subunit B; SPTR: ATP synthase subunit b YP_004371469.1 COGs: COG1376 conserved hypothetical protein; InterPro IPR002482:IPR018392:IPR005490; KEGG: glo:Glov_0755 ErfK/YbiS/YcfS/YnhG family protein; PFAM: YkuD domain; peptidoglycan-binding lysin domain; SMART: peptidoglycan-binding Lysin subgroup; SPTR: ErfK/YbiS/YcfS/YnhG family protein; PFAM: LysM domain; L,D-transpeptidase catalytic domain YP_004371470.1 COGs: COG3568 Metal-dependent hydrolase; InterPro IPR005135; KEGG: sfu:Sfum_0613 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/Exonuclease/phosphatase YP_004371471.1 COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006674; KEGG: dol:Dole_1124 metal-dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Metal-dependent phosphohydrolase HD sub domain; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase YP_004371472.1 COGs: COG0863 DNA modification methylase; InterPro IPR002941; KEGG: dth:DICTH_0253 m4C-methyltransferase; PFAM: DNA methylase N-4/N-6; SPTR: Type II restriction modification system, methylation subunit; PFAM: DNA methylase YP_004371473.1 InterPro IPR007138; KEGG: sfu:Sfum_2110 antibiotic biosynthesis monooxygenase; PFAM: Antibiotic biosynthesis monooxygenase; SPTR: Antibiotic biosynthesis monooxygenase; PFAM: Antibiotic biosynthesis monooxygenase YP_004371474.1 COGs: COG4974 Site-specific recombinase XerD; HAMAP: Tyrosine recombinase xerC; InterPro IPR004107:IPR002104; KEGG: pca:Pcar_0623 site-specific recombinase; PFAM: Integrase, catalytic core, phage; Integrase, N-terminal SAM-like, phage; SPTR: Site-specific recombinase; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase; TIGRFAM: tyrosine recombinase XerC YP_004371475.1 COGs: COG5405 ATP-dependent protease HslVU (ClpYQ) peptidase subunit; HAMAP: ATP-dependent protease, HslV subunit; InterPro IPR001353:IPR022281; KEGG: dal:Dalk_0404 ATP-dependent protease peptidase subunit; PFAM: Proteasome, subunit alpha/beta; SPTR: ATP-dependent protease subunit HslV; TIGRFAM: ATP-dependent protease, HslV subunit; PFAM: Proteasome subunit; TIGRFAM: ATP-dependent protease HslVU, peptidase subunit YP_004371476.1 COGs: COG1220 ATP-dependent protease HslVU (ClpYQ) ATPase subunit; HAMAP: Heat shock protein HslU; InterPro IPR003593:IPR013093:IPR019489:IPR004491; KEGG: sfu:Sfum_0065 ATP-dependent protease ATP-binding subunit HslU; PFAM: ATPase, AAA-2; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent protease ATPase subunit HslU; TIGRFAM: Heat shock protein HslU; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ATPase associated with various cellular activities (AAA); TIGRFAM: ATP-dependent protease HslVU, ATPase subunit YP_004371477.1 InterPro IPR008815; KEGG: sul:SYO3AOP1_0925 S23 ribosomal protein; PFAM: 23S rRNA-associated protein; SPTR: S23 ribosomal protein; PFAM: S23 ribosomal protein YP_004371478.1 COGs: COG0548 Acetylglutamate kinase; InterPro IPR001048:IPR004662; KEGG: sfu:Sfum_0064 acetylglutamate kinase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: Acetylglutamate kinase; SPTR: Acetylglutamate kinase; TIGRFAM: Acetylglutamate kinase; PFAM: Amino acid kinase; TIGRFAM: acetylglutamate kinase YP_004371479.1 COGs: COG4992 ornithine/acetylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; InterPro IPR005814:IPR004636; KEGG: sat:SYN_02155 acetylornithine aminotransferase; PFAM: Aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Acetylornithine aminotransferase; TIGRFAM: Acetylornithine/succinylornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases YP_004371480.1 COGs: COG0078 ornithine carbamoyltransferase; HAMAP: ornithine carbamoyltransferase; InterPro IPR006132:IPR006131:IPR002292; KEGG: dbr:Deba_1882 ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; PRIAM: ornithine carbamoyltransferase; SPTR: ornithine carbamoyltransferase; TIGRFAM: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase YP_004371481.1 InterPro IPR006442; KEGG: sti:Sthe_3417 prevent-host-death family protein; SPTR: Prevent-host-death family protein; TIGRFAM: Prevent-host-death protein; PFAM: Phd_YefM YP_004371482.1 KEGG: mar:MAE_57700 hypothetical protein; SPTR: uncharacterized protein YP_004371483.1 InterPro IPR013099; KEGG: cyt:cce_1189 ion transport protein; PFAM: Ion transport 2; SPTR: uncharacterized protein; PFAM: Ion channel YP_004371484.1 COGs: COG0137 argininosuccinate synthase; HAMAP: argininosuccinate synthase; InterPro IPR001518; KEGG: dbr:Deba_1881 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: argininosuccinate synthase; SPTR: argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: arginosuccinate synthase; TIGRFAM: argininosuccinate synthase YP_004371485.1 KEGG: pth:PTH_1499 integral membrane protein; SPTR: uncharacterized protein YP_004371486.1 COGs: COG1943 transposase and inactivated derivatives; KEGG: nhl:Nhal_2837 protein of unknown function DUF1568; SPTR: uncharacterized protein; PFAM: transposase IS200 like YP_004371487.1 COGs: COG0165 argininosuccinate lyase; HAMAP: argininosuccinate lyase; InterPro IPR009049:IPR022761; KEGG: dak:DaAHT2_2213 argininosuccinate lyase; PFAM: Lyase 1, N-terminal; PRIAM: argininosuccinate lyase; SPTR: argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase YP_004371488.1 InterPro IPR003961; KEGG: dps:DP0434 hypothetical protein; PFAM: Fibronectin, type III; SPTR: Fibronectin, type III YP_004371489.1 COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR022644:IPR022643:IPR002986; KEGG: sat:SYN_02160 diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2, N-terminal; Orn/DAP/Arg decarboxylase 2, C-terminal; PRIAM: Diaminopimelate decarboxylase; SPTR: Diaminopimelate decarboxylase; TIGRFAM: Diaminopimelate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: diaminopimelate decarboxylase YP_004371490.1 COGs: COG0253 Diaminopimelate epimerase; HAMAP: Diaminopimelate epimerase; InterPro IPR001653; KEGG: sfu:Sfum_0057 diaminopimelate epimerase; PFAM: Diaminopimelate epimerase; SPTR: Diaminopimelate epimerase; TIGRFAM: Diaminopimelate epimerase; PFAM: Diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase YP_004371491.1 COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; HAMAP: dihydrodipicolinate synthase; InterPro IPR002220:IPR005263; KEGG: sat:SYN_02161 dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; PRIAM: dihydrodipicolinate synthase; SPTR: dihydrodipicolinate synthase; TIGRFAM: dihydrodipicolinate synthase subfamily; PFAM: dihydrodipicolinate synthetase; TIGRFAM: dihydrodipicolinate synthase YP_004371492.1 COGs: COG0289 dihydrodipicolinate reductase; HAMAP: dihydrodipicolinate reductase, bacterial/plant; InterPro IPR011770:IPR000846:IPR022663; KEGG: sat:SYN_02162 dihydrodipicolinate reductase; PFAM: dihydrodipicolinate reductase, C-terminal; dihydrodipicolinate reductase, N-terminal; PRIAM: dihydrodipicolinate reductase; SPTR: dihydrodipicolinate reductase; TIGRFAM: dihydrodipicolinate reductase, bacterial/plant; manually curated; PFAM: dihydrodipicolinate reductase, N-terminus; dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase YP_004371493.1 COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR018833:IPR002529; KEGG: dly:Dehly_1008 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: Fumarylacetoacetase, C-terminal-like; Domain of unknown function DUF2437; PRIAM: Ureidoglycolate lyase; SPTR: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase YP_004371494.1 COGs: COG3809 conserved hypothetical protein; KEGG: gem:GM21_2278 hypothetical protein; SPTR: uncharacterized protein YP_004371495.1 COGs: COG0436 aspartate/tyrosine/aromatic aminotransferase; HAMAP: LL-diaminopimelate aminotransferase; InterPro IPR004839:IPR019881; KEGG: sfu:Sfum_0054 aminotransferase, class I and II; PFAM: Aminotransferase, class I/classII; PRIAM: LL-diaminopimelate aminotransferase; SPTR: LL-diaminopimelate aminotransferase; TIGRFAM: LL-diaminopimelate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: LL-diaminopimelate aminotransferase YP_004371496.1 KEGG: mbt:JTY_0591 transcriptional regulatory protein; SPTR: PROBABLE transCRIPTIONAL REGULATORY protein (POSSIBLY ARSR-FAMILY) YP_004371497.1 COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: sat:SYN_02163 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HppK); PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_004371498.1 InterPro IPR007029; KEGG: glo:Glov_0374 hypothetical protein; PFAM: YHS; SPTR: uncharacterized protein; PFAM: YHS domain YP_004371499.1 COGs: COG0176 transaldolase; HAMAP: transaldolase 3B, InterPro IPR022999:IPR001585:IPR004731; KEGG: sfu:Sfum_0051 transaldolase; PFAM: transaldolase; SPTR: Probable transaldolase; TIGRFAM: transaldolase 3A/3B; PFAM: transaldolase; TIGRFAM: fructose-6-phosphate aldolase, TalC/MipB family YP_004371500.1 COGs: COG0558 phosphatidylglycerophosphate synthase; InterPro IPR000462:IPR004570; KEGG: dma:DMR_21580 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_004371501.1 COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: pcl:Pcal_1387 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain; SPTR: Aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase YP_004371502.1 InterPro IPR001387:IPR013096; KEGG: kfl:Kfla_6558 XRE family transcriptional regulator; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3; SPTR: Helix-turn-helix domain protein; PFAM: Cupin domain; Helix-turn-helix YP_004371503.1 InterPro IPR008254; KEGG: dsa:Desal_0459 hypothetical protein; PFAM: Flavodoxin/nitric oxide synthase; SPTR: uncharacterized protein; PFAM: Flavodoxin YP_004371504.1 InterPro IPR014925; KEGG: dae:Dtox_3196 hypothetical protein; PFAM: Uncharacterised protein domain CGGC-dom; SPTR: uncharacterized protein; PFAM: CGGC domain YP_004371505.1 COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR000523:IPR003593; KEGG: cts:Ctha_2442 magnesium chelatase; PFAM: Magnesium chelatase, ChlI subunit; PRIAM: Magnesium chelatase; SMART: ATPase, AAA+ type, core; SPTR: Magnesium-chelatase subunit chlI homolog; PFAM: Magnesium chelatase, subunit ChlI YP_004371506.1 COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR000523:IPR002035:IPR012804:IPR003593; KEGG: ppd:Ppro_1261 magnesium chelatase; PFAM: von Willebrand factor, type A; Magnesium chelatase, ChlI subunit; PRIAM: Magnesium chelatase; SMART: von Willebrand factor, type A; ATPase, AAA+ type, core; SPTR: uncharacterized protein; TIGRFAM: Cobaltochelatase subunit; PFAM: Magnesium chelatase, subunit ChlI; von Willebrand factor type A domain; TIGRFAM: cobaltochelatase subunit YP_004371507.1 COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003672; KEGG: adg:Adeg_1646 cobaltochelatase; PFAM: CobN/magnesium chelatase; PRIAM: Cobaltochelatase; SPTR: Cobaltochelatase; PFAM: CobN/Magnesium Chelatase; TIGRFAM: cobaltochelatase, CobN subunit YP_004371508.1 COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: ppd:Ppro_2081 ABC transporter related; PFAM: ABC transporter-like; PRIAM: iron ABC transporter ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter YP_004371509.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: ppd:Ppro_2080 transport system permease; PFAM: ABC transporter permease; SPTR: transport system permease; PFAM: FecCD transport family YP_004371510.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: sfu:Sfum_0493 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein; PFAM: Periplasmic binding protein YP_004371511.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: sfu:Sfum_0492 TonB-dependent receptor; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; SPTR: TonB-dependent receptor; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004371512.1 COGs: COG0497 ATPase involved in DNA repair; InterPro IPR003395:IPR004604; KEGG: gsu:GSU2064 DNA repair protein RecN; PFAM: RecF/RecN/SMC; SPTR: DNA repair protein RecN; TIGRFAM: DNA recombination/repair protein RecN; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: DNA repair protein RecN YP_004371513.1 KEGG: sfu:Sfum_4098 hypothetical protein; SPTR: uncharacterized protein YP_004371514.1 InterPro IPR005357; KEGG: mpi:Mpet_1167 hypothetical protein; PFAM: Uncharacterised protein family UPF0150; SPTR: uncharacterized protein YP_004371515.1 COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: dak:DaAHT2_0504 peptidase U32; PFAM: peptidase U32; SPTR: peptidase U32; PFAM: peptidase U32 YP_004371516.1 COGs: COG0107 Imidazoleglycerol-phosphate synthase; HAMAP: histidine biosynthesis, HisF; InterPro IPR004651:IPR006062; KEGG: sat:SYN_01451 imidazole glycerol phosphate synthase, cyclase subunit; PFAM: histidine biosynthesis; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidazole-4-carboxamideisomerase; SPTR: Imidazole glycerol phosphate synthase subunit hisF 1; TIGRFAM: histidine biosynthesis, HisF; PFAM: histidine biosynthesis protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit YP_004371517.1 COGs: COG3404 methenyl tetrahydrofolate cyclohydrolase; InterPro IPR007044; KEGG: pmo:Pmob_1031 formiminotransferase-cyclodeaminase; PFAM: Cyclodeaminase/cyclohydrolase; SPTR: formiminotransferase-cyclodeaminase; PFAM: formiminotransferase-cyclodeaminase YP_004371518.1 KEGG: aae:aq_1457 hypothetical protein; SPTR: uncharacterized protein YP_004371519.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR003018:IPR000160; KEGG: glo:Glov_1844 diguanylate cyclase with GAF sensor; PFAM: Diguanylate cyclase, predicted; GAF; SMART: Diguanylate cyclase, predicted; GAF; SPTR: Diguanylate cyclase with GAF sensor; TIGRFAM: Diguanylate cyclase, predicted; PFAM: GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004371520.1 COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR001347:IPR000644:IPR004800; KEGG: sfu:Sfum_0006 KpsF/GutQ family protein; PFAM: Sugar isomerase (SIS); cystathionine beta-synthase, core; PRIAM: Arabinose-5-phosphate isomerase; SMART: cystathionine beta-synthase, core; SPTR: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein YP_004371521.1 KEGG: sul:SYO3AOP1_1287 metallophosphoesterase; SPTR: uncharacterized protein YP_004371523.1 KEGG: dak:DaAHT2_1673 heat repeat-containing PBS lyase; SPTR: uncharacterized protein YP_004371524.1 COGs: COG0065 3-isopropylmalate dehydratase large subunit; HAMAP: Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic; InterPro IPR011826:IPR001030:IPR011823:IPR006251; KEGG: dal:Dalk_0181 3-isopropylmalate dehydratase large subunit; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; SPTR: 3-isopropylmalate dehydratase large subunit; TIGRFAM: 3-isopropylmalate dehydratase, large subunit, prokaryotic; Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic; Homoaconitase/3-isopropylmalate dehydratase, large subunit, subgroup; PFAM: Aconitase (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit; homoaconitate hydratase YP_004371525.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013709:IPR005671; KEGG: sat:SYN_00090 2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; PRIAM: 2-isopropylmalate synthase; SMART: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; SPTR: 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase, bacterial type; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase, bacterial type YP_004371526.1 COGs: COG1183 phosphatidylserine synthase; InterPro IPR000462:IPR004533; KEGG: glo:Glov_2499 CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol/serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase YP_004371527.1 COGs: COG0688 phosphatidylserine decarboxylase; HAMAP: phosphatidylserine decarboxylase-related protein; InterPro IPR004428:IPR003817; KEGG: dak:DaAHT2_0727 phosphatidylserine decarboxylase related protein; PFAM: phosphatidylserine decarboxylase-related; PRIAM: phosphatidylserine decarboxylase; SPTR: phosphatidylserine decarboxylase proenzyme; TIGRFAM: phosphatidylserine decarboxylase-related protein; PFAM: phosphatidylserine decarboxylase; TIGRFAM: phosphatidylserine decarboxylase precursor-related protein YP_004371528.1 COGs: COG0059 Ketol-acid reductoisomerase; HAMAP: Acetohydroxy acid isomeroreductase; InterPro IPR013023:IPR013116:IPR000506; KEGG: sfu:Sfum_3026 ketol-acid reductoisomerase; PFAM: Acetohydroxy acid isomeroreductase, catalytic; Acetohydroxy acid isomeroreductase C-terminal; PRIAM: Ketol-acid reductoisomerase; SPTR: Ketol-acid reductoisomerase; TIGRFAM: Acetohydroxy acid isomeroreductase; PFAM: Acetohydroxy acid isomeroreductase, catalytic domain; TIGRFAM: ketol-acid reductoisomerase YP_004371529.1 InterPro IPR000074; KEGG: mse:Msed_1021 hypothetical protein; PFAM: Apolipoprotein A1/A4/E; SPTR: uncharacterized protein YP_004371530.1 COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR019455:IPR004789; KEGG: dak:DaAHT2_0726 acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT; SPTR: Acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit YP_004371531.1 COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001:IPR012000:IPR011766:IPR012846; KEGG: dba:Dbac_0408 acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase; TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type YP_004371532.1 KEGG: dbr:Deba_0750 hypothetical protein; SPTR: uncharacterized protein YP_004371533.1 KEGG: dvm:DvMF_2093 hypothetical protein; SPTR: uncharacterized protein YP_004371534.1 InterPro IPR018383; KEGG: adg:Adeg_1188 uncharacterized protein family UPF0324; PFAM: Uncharacterised protein family UPF0324, prokaryote; SPTR: Uncharacterized protein family UPF0324; PFAM: Conserved hypothetical protein 698 YP_004371535.1 COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: sfu:Sfum_3410 dinitrogenase iron-molybdenum cofactor biosynthesis; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; SPTR: Dinitrogenase iron-molybdenum cofactor biosynthesis; PFAM: Dinitrogenase iron-molybdenum cofactor YP_004371536.1 COGs: COG1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain; InterPro IPR002586:IPR001450; KEGG: sfu:Sfum_3409 cobyrinic acid a,c-diamide synthase; PFAM: cobyrinic acid a,c-diamide synthase; 4Fe-4S binding domain; SPTR: cobyrinic acid a,c-diamide synthase; PFAM: 4Fe-4S binding domain; CobQ/CobB/MinD/ParA nucleotide binding domain YP_004371537.1 COGs: COG1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain; InterPro IPR002586:IPR001450; KEGG: sfu:Sfum_3408 cobyrinic acid a,c-diamide synthase; PFAM: cobyrinic acid a,c-diamide synthase; 4Fe-4S binding domain; SPTR: cobyrinic acid a,c-diamide synthase; PFAM: 4Fe-4S binding domain; CobQ/CobB/MinD/ParA nucleotide binding domain YP_004371538.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: pca:Pcar_2671 SAM-dependent methyltransferase; PFAM: methyltransferase type 11; SPTR: SAM-dependent methyltransferase; PFAM: methyltransferase domain YP_004371539.1 COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR005835:IPR005907; KEGG: sfu:Sfum_2263 glucose-1-phosphate thymidylyltransferase; PFAM: nucleotidyl transferase; PRIAM: glucose-1-phosphate thymidylyltransferase; SPTR: glucose-1-phosphate thymidylyltransferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase, long form; PFAM: nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase, short form YP_004371540.1 COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: rmr:Rmar_1316 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-glucose 4-epimerase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase YP_004371541.1 InterPro IPR000086; KEGG: ach:Achl_3962 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase; PFAM: NUDIX domain YP_004371542.1 KEGG: pbe:PB000580.00.0 hypothetical protein; SPTR: uncharacterized protein YP_004371543.1 COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR005888; KEGG: mei:Msip34_1447 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: dTDP-glucose 4,6-dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase YP_004371544.1 COGs: COG1898 dTDP-4-dehydrorhamnose 3 5-epimerase; InterPro IPR000888; KEGG: rxy:Rxyl_3120 dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase-related; PRIAM: dTDP-4-dehydrorhamnose 3,5-epimerase; SPTR: dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase-related; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase YP_004371545.1 COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR005913; KEGG: dal:Dalk_2507 dTDP-4-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase; PRIAM: dTDP-4-dehydrorhamnose reductase; SPTR: dTDP-4-dehydrorhamnose reductase; TIGRFAM: dTDP-4-dehydrorhamnose reductase; PFAM: RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose reductase YP_004371546.1 InterPro IPR006016; KEGG: tye:THEYE_A0732 universal stress protein family; PFAM: UspA; SPTR: Universal stress protein family; PFAM: Universal stress protein family YP_004371547.1 COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: dak:DaAHT2_1954 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; PFAM: methyltransferase domain YP_004371548.1 InterPro IPR013216; KEGG: tgr:Tgr7_1418 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; PFAM: methyltransferase domain YP_004371549.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: tye:THEYE_A0732 universal stress protein family; PFAM: UspA; SPTR: Universal stress protein family; PFAM: Universal stress protein family YP_004371550.1 COGs: COG0177 EndoIII-related endonuclease; InterPro IPR003265:IPR003651:IPR005759; KEGG: sfu:Sfum_1062 endonuclease III; PFAM: HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD domain; SPTR: Endonuclease III / DNA-(Apurinic or apyrimidinic site) lyase; TIGRFAM: Endonuclease III/Nth; PFAM: HhH-GPD superfamily base excision DNA repair protein; Helix-hairpin-helix motif; TIGRFAM: endonuclease III YP_004371551.1 COGs: COG0728 membrane protein virulence factor; InterPro IPR004268; KEGG: dps:DP2399 virulence factor (MviN); PFAM: Flagellin assembly, membrane protein MviN; SPTR: Virulence factor MVIN-like; TIGRFAM: Flagellin assembly, membrane protein MviN; PFAM: MviN-like protein; TIGRFAM: integral membrane protein MviN YP_004371552.1 KEGG: cag:Cagg_1521 cytochrome c oxidase, subunit I; SPTR: uncharacterized protein YP_004371553.1 COGs: COG0566 rRNA methylase; InterPro IPR013123:IPR001537:IPR004441; KEGG: acp:A2cp1_2368 RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; SMART: RNA 2-O ribose methyltransferase, substrate binding; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: SpoU rRNA methylase; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, , group 3 YP_004371554.1 KEGG: bgl:bglu_1g11810 hypothetical protein; SPTR: uncharacterized protein YP_004371555.1 COGs: COG4637 ATPase; KEGG: cyc:PCC7424_2033 ATPase; SPTR: ABC transporter, ATP-binding subunit YP_004371556.1 COGs: COG1285 membrane protein; InterPro IPR003416; KEGG: sfu:Sfum_3054 MgtC/SapB transporter; PFAM: MgtC/SapB transporter; SPTR: MgtC/SapB transporter; PFAM: MgtC family YP_004371557.1 COGs: COG0755 ABC-type transport system involved in cytochrome c biogenesis permease component; InterPro IPR002541:IPR017562; KEGG: sat:SYN_00150 heme export protein apocytochrome heme-lyase; PFAM: Cytochrome c assembly protein; SPTR: Cytochrome c-type biogenesis protein CcsB; TIGRFAM: Cytochrome c-type biogenesis protein CcsA; PFAM: Cytochrome C assembly protein; TIGRFAM: cytochrome c-type biogenesis protein CcsB YP_004371558.1 COGs: COG1333 ResB protein required for cytochrome c biosynthesis; InterPro IPR007816; KEGG: pca:Pcar_2229 ResB-like cytochrome c biosythesis protein; PFAM: Cytochrome c biogenesis protein; SPTR: ResB-like cytochrome c biosythesis protein; PFAM: ResB-like family YP_004371559.1 COGs: COG0509 glycine cleavage system H protein (lipoate-binding); HAMAP: glycine cleavage H-protein; InterPro IPR002930; KEGG: gme:Gmet_0985 glycine cleavage system H protein; PFAM: glycine cleavage H-protein; SPTR: glycine cleavage system H protein 1; PFAM: glycine cleavage H-protein; TIGRFAM: glycine cleavage system H protein YP_004371560.1 COGs: COG1073 Hydrolase of the alpha/beta superfamily; InterPro IPR000073; KEGG: dbr:Deba_0674 enzyme (3.4.-); PFAM: Alpha/beta hydrolase fold-1; SPTR: enzyme (3.4.-); PFAM: alpha/beta hydrolase fold YP_004371561.1 COGs: COG4231 Indolepyruvate ferredoxin oxidoreductase alpha and beta subunits; InterPro IPR011766:IPR001450:IPR017721; KEGG: dol:Dole_0440 thiamine pyrophosphate binding domain-containing protein; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; 4Fe-4S binding domain; PRIAM: Indolepyruvate ferredoxin oxidoreductase; SPTR: Thiamine pyrophosphate protein domain protein TPP-binding; TIGRFAM: Indolepyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, alpha subunit YP_004371562.1 COGs: COG1014 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: dat:HRM2_11240 IorB1; PFAM: pyruvate/ketoisovalerate oxidoreductase, catalytic domain; PRIAM: Indolepyruvate ferredoxin oxidoreductase; SPTR: indolepyruvate ferredoxin oxidoreductase, beta subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, beta subunit YP_004371563.1 KEGG: drt:Dret_2004 hypothetical protein; SPTR: uncharacterized protein; PFAM: exonuclease, RdgC YP_004371564.1 KEGG: sat:SYN_02864 cytoplasmic protein; SPTR: Hypothetical cytosolic protein YP_004371565.1 COGs: COG0266 formamidopyrimidine-DNA glycosylase; HAMAP: formamidopyrimidine-DNA glycosylase; InterProIPR020629:IPR012319:IPR015886:IPR010663:IPR 000191; KEGG: gvi:gvip464 formamidopyrimidine-DNA glycosylase; PFAM: DNA glycosylase/AP lyase, catalytic domain; DNA glycosylase/AP lyase, H2TH DNA-binding; Zinc finger, DNA glycosylase/AP lyase/isoleucyl tRNA synthetase; PRIAM: DNA-formamidopyrimidine glycosylase; SMART: DNA glycosylase/AP lyase, catalytic domain; SPTR: formamidopyrimidine-DNA glycosylase; TIGRFAM: DNA glycosylase/AP lyase; PFAM: formamidopyrimidine-DNA glycosylase H2TH domain; formamidopyrimidine-DNA glycosylase N-terminal domain; Zinc finger found in FPG and IleRS; TIGRFAM: formamidopyrimidine-DNA glycosylase (fpg) YP_004371566.1 COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR013982; KEGG: sfu:Sfum_3083 AICARFT/IMPCHase bienzyme, formylation region; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; PRIAM: phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, transformylase domain; SPTR: AICARFT/IMPCHase bienzyme; PFAM: AICARFT/IMPCHase bienzyme YP_004371567.1 KEGG: mxa:MXAN_2242 lipoprotein; SPTR: Von Willebrand factor type D domain protein YP_004371568.1 COGs: COG0305 Replicative DNA helicase; InterPro IPR007693:IPR007694:IPR007692; KEGG: dak:DaAHT2_1151 replicative DNA helicase; PFAM: DNA helicase, DnaB-like, C-terminal; DNA helicase, DnaB-like, N-terminal; SPTR: DnaB helicase; TIGRFAM: DNA helicase, DnaB type; PFAM: DnaB-like helicase N terminal domain; DnaB-like helicase C terminal domain; TIGRFAM: replicative DNA helicase YP_004371569.1 COGs: COG0524 Sugar kinase ribokinase; InterPro IPR011611; KEGG: dsa:Desal_2501 PfkB domain protein; PFAM: Carbohydrate/purine kinase; PRIAM: adenosine kinase; SPTR: PfkB domain protein; PFAM: pfkB family carbohydrate kinase YP_004371570.1 KEGG: dya:Dyak_GE10791 GE10791 gene product from transcript GE10791-RA YP_004371571.1 COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805:IPR015890:IPR005802; KEGG: sfu:Sfum_3709 para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Aminodeoxychorismate synthase, subunit I; TIGRFAM: Para-aminobenzoate synthase, component I; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme YP_004371572.1 COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR000991:IPR006221; KEGG: sfu:Sfum_3710 glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Aminodeoxychorismate synthase, glutamine amidotransferase subunit; TIGRFAM: Anthranilate synthase, glutamine amidotransferase domain; PFAM: glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase YP_004371573.1 COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR004013:IPR003141; KEGG: tjr:TherJR_2593 PHP domain protein; PFAM: PHP, C-terminal; SMART: polymerase/histidinol phosphatase, N-terminal; SPTR: PHP domain protein; PFAM: PHP domain YP_004371574.1 COGs: COG0295 Cytidine deaminase; InterPro IPR002125:IPR006262; KEGG: rca:Rcas_0739 cytidine deaminase; PFAM: CMP/dCMP deaminase, zinc-binding; SPTR: Cytidine deaminase; TIGRFAM: Cytidine deaminase, homotetrameric; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric YP_004371575.1 COGs: COG0352 Thiamine monophosphate synthase; HAMAP: Thiamine monophosphate synthase; InterPro IPR003733; KEGG: mmh:Mmah_0937 thiamine-phosphate diphosphorylase; PFAM: Thiamine monophosphate synthase; SPTR: Thiamine-phosphate pyrophosphorylase; TIGRFAM: Thiamine monophosphate synthase; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase YP_004371576.1 COGs: COG2145 Hydroxyethylthiazole kinase sugar kinase; HAMAP: Hydroxyethylthiazole kinase; InterPro IPR000417; KEGG: mma:MM_3234 hydroxyethylthiazole kinase; PFAM: Hydroxyethylthiazole kinase; PRIAM: Hydroxyethylthiazole kinase; SPTR: Hydroxyethylthiazole kinase; PFAM: Hydroxyethylthiazole kinase; TIGRFAM: hydroxyethylthiazole kinase YP_004371577.1 COGs: COG0008 glutamyl- and glutaminyl-tRNA synthetase; HAMAP: glutaminyl-tRNA synthetase, bacterial; InterPro IPR022861:IPR020058:IPR020059:IPR004514; KEGG: sfu:Sfum_3516 glutaminyl-tRNA synthetase; PFAM: glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain; PRIAM: glutamine--tRNA ligase; SPTR: glutaminyl-tRNA synthetase; TIGRFAM: glutaminyl-tRNA synthetase, class Ic; PFAM: tRNA synthetases class I (E and Q), catalytic domain; tRNA synthetases class I (E and Q), anti-codon binding domain; TIGRFAM: glutaminyl-tRNA synthetase YP_004371578.1 COGs: COG2361 conserved hypothetical protein; InterPro IPR008201; KEGG: rca:Rcas_2417 hypothetical protein; PFAM: protein of unknown function DUF86; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF86 YP_004371579.1 COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: rca:Rcas_2416 DNA polymerase subunit beta; PFAM: nucleotidyl transferase domain; SPTR: DNA polymerase beta domain protein region; PFAM: nucleotidyltransferase domain YP_004371580.1 COGs: COG1796 DNA polymerase IV (family X); InterPro IPR004013:IPR002054:IPR003583:IPR003141; KEGG: geo:Geob_1150 PHP domain protein; PFAM: PHP, C-terminal; SMART: DNA-directed DNA polymerase X; Helix-hairpin-helix DNA-binding motif, class 1; polymerase/histidinol phosphatase, N-terminal; SPTR: PHP domain protein; PFAM: PHP domain YP_004371581.1 KEGG: dbr:Deba_1406 hypothetical protein; SPTR: uncharacterized protein YP_004371582.1 COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR013767:IPR003661:IPR003594:IPR001789:IPR 000014:IPR001610; KEGG: dal:Dalk_3513 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004371583.1 COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR002142:IPR004635; KEGG: nde:NIDE2543 signal peptide peptidase SppA; PFAM: peptidase S49; SPTR: Signal peptide peptidase SppA (Protease IV); TIGRFAM: peptidase S49, SppA; PFAM: peptidase S49; TIGRFAM: signal peptide peptidase SppA, 36K type YP_004371584.1 KEGG: cha:CHAB381_0868 hypothetical protein; SPTR: uncharacterized protein YP_004371585.1 InterPro IPR003369; KEGG: tjr:TherJR_1816 twin-arginine translocation protein, TatA/E family subunit; PFAM: Bacterial sec-independent translocation protein MttA/Hcf106; SPTR: Sec-independent protein translocase tatA/E homolog; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family YP_004371586.1 COGs: COG1826 Sec-independent protein secretion pathway components; HAMAP: Twin-arginine translocation protein TatA/E; InterPro IPR006312:IPR003369; KEGG: gvi:gsl0711 hypothetical protein; PFAM: Bacterial sec-independent translocation protein MttA/Hcf106; SPTR: Sec-independent protein translocase tatA/E homolog 3; TIGRFAM: Twin-arginine translocation protein TatA/E; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family YP_004371587.1 COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003959:IPR003593; KEGG: rmr:Rmar_0323 ATPase AAA; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: ATPase AAA; PFAM: MgsA AAA+ ATPase C terminal; ATPase associated with various cellular activities (AAA) YP_004371588.1 KEGG: dat:HRM2_28750 hypothetical protein; SPTR: uncharacterized protein; PFAM: peptidase M50 YP_004371589.1 InterPro IPR011701; KEGG: dat:HRM2_28740 OxlT; PFAM: Major facilitator superfamily MFS-1; SPTR: OxlT; PFAM: Major Facilitator Superfamily YP_004371590.1 KEGG: tet:TTHERM_00760700 hypothetical protein YP_004371591.1 COGs: COG0001 glutamate-1-semialdehyde aminotransferase; HAMAP: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; InterPro IPR004639:IPR005814; KEGG: sti:Sthe_1801 glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; PRIAM: glutamate-1-semialdehyde 2,1-aminomutase; SPTR: glutamate-1-semialdehyde 2,1-aminomutase; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase YP_004371592.1 COGs: COG1522 transcriptional regulators; KEGG: dat:HRM2_05170 HTH-type transcriptional regulator; SPTR: Heme d1 biosynthesis protein YP_004371593.1 COGs: COG2005 N-terminal domain of molybdenum-binding protein; InterPro IPR000847; KEGG: sat:SYN_01042 transcriptional regulator LysR; PFAM: HTH transcriptional regulator, LysR; SPTR: Molybdenum transport regulatory protein, lysR family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: ModE molybdate transport repressor domain YP_004371594.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: pth:PTH_0856 hypothetical protein; PFAM: Lytic transglycosylase-like, catalytic; SPTR: uncharacterized protein; PFAM: transglycosylase SLT domain YP_004371595.1 KEGG: dya:Dyak_GE25700 GE25700 gene product from transcript GE25700-RA; SPTR: GE25700 YP_004371596.1 KEGG: dma:DMR_18250 hypothetical protein; SPTR: uncharacterized protein YP_004371597.1 COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: pth:PTH_0986 hypothetical protein; PFAM: Uncharacterised protein family UPF0047; SPTR: Uncharacterized conserved protein; TIGRFAM: Uncharacterised protein family UPF0047; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme YP_004371598.1 KEGG: ank:AnaeK_1184 hypothetical protein; SPTR: uncharacterized protein YP_004371599.1 COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; HAMAP: bifunctional protein PyrR; InterPro IPR023050:IPR000836; KEGG: sfu:Sfum_1064 uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: bifunctional protein pyrR; PFAM: phosphoribosyl transferase domain YP_004371600.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: nde:NIDE2697 capsular polysaccharide biosynthesis glycosyltransferase CapM; PFAM: glycosyl transferase, group 1; SPTR: Capsular polysaccharide biosynthesis glycosyltransferase CapM; PFAM: glycosyl transferases group 1 YP_004371602.1 COGs: COG0359 ribosomal protein L9; HAMAP: ribosomal protein L9, bacteria/chloroplast; InterPro IPR020594:IPR020070:IPR020069; KEGG: dma:DMR_27020 50S ribosomal protein L9; PFAM: ribosomal protein L9, C-terminal; ribosomal protein L9, N-terminal; SPTR: 50S ribosomal protein L9; TIGRFAM: ribosomal protein L9, bacteria/chloroplast; PFAM: ribosomal protein L9, N-terminal domain; ribosomal protein L9, C-terminal domain; TIGRFAM: ribosomal protein L9 YP_004371603.1 InterPro IPR018710; KEGG: gsu:GSU0667 hypothetical protein; PFAM: protein of unknown function DUF2232, membrane; SPTR: Membrane protein, ; PFAM: Predicted membrane protein (DUF2232) YP_004371604.1 COGs: COG0238 ribosomal protein S18; HAMAP: ribosomal protein S18; InterPro IPR001648; KEGG: sfu:Sfum_3187 ribosomal protein S18; PFAM: ribosomal protein S18; SPTR: 30S ribosomal protein S18; TIGRFAM: ribosomal protein S18; PFAM: ribosomal protein S18; TIGRFAM: ribosomal protein S18 YP_004371605.1 COGs: COG0360 ribosomal protein S6; HAMAP: ribosomal protein S6, plastid/chloroplast; InterPro IPR020814:IPR000529; KEGG: dal:Dalk_0919 30S ribosomal protein S6; PFAM: ribosomal protein S6; SPTR: 30S ribosomal protein S6; TIGRFAM: ribosomal protein S6; PFAM: ribosomal protein S6; TIGRFAM: ribosomal protein S6 YP_004371606.1 KEGG: sat:SYN_03002 hypothetical protein; SPTR: Hypothetical membrane protein YP_004371607.1 KEGG: sat:SYN_03002 hypothetical protein; SPTR: Hypothetical membrane protein YP_004371608.1 COGs: COG0781 transcription termination factor; HAMAP: NusB antitermination factor; InterPro IPR011605:IPR006027; KEGG: ank:AnaeK_2830 NusB antitermination factor; PFAM: NusB/RsmB/TIM44; SPTR: N utilization substance protein B homolog; TIGRFAM: NusB antitermination factor; PFAM: NusB family; TIGRFAM: transcription antitermination factor NusB YP_004371609.1 COGs: COG0054 riboflavin synthase beta-chain; HAMAP: 6,7-dimethyl-8-ribityllumazine synthase; InterPro IPR002180; KEGG: sat:SYN_02372 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase; SPTR: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase YP_004371610.1 COGs: COG0108 3 4-dihydroxy-2-butanone 4-phosphate synthase; HAMAP: 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB; GTP cyclohydrolase II, RibA; riboflavin biosynthesis protein RibBA; InterPro IPR000926:IPR000422:IPR016299; KEGG: sat:SYN_02371 GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone-4-phosphate synthase; PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB; GTP cyclohydrolase II, RibA; SPTR: GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone-4-phosphate synthase; TIGRFAM: GTP cyclohydrolase II, RibA; 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB; PFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_004371611.1 COGs: COG0307 riboflavin synthase alpha chain; InterPro IPR001783; KEGG: gsu:GSU1689 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: riboflavin synthase; SPTR: riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit YP_004371612.1 KEGG: gur:Gura_0134 hypothetical protein; SPTR: uncharacterized protein; PFAM: TM2 domain YP_004371613.1 COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR002825; KEGG: afw:Anae109_3319 hypothetical protein; PFAM: peptidase S49, serine-peptidase prokaryotes; SPTR: uncharacterized protein; PFAM: Serine dehydrogenasease YP_004371614.1 KEGG: dat:HRM2_16930 hypothetical protein; SPTR: uncharacterized protein YP_004371615.1 COGs: COG3956 protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: gem:GM21_0909 nucleoside triphosphate pyrophosphohydrolase; PFAM: NTP pyrophosphohydrolase MazG, catalytic core; SPTR: MazG family protein; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein YP_004371616.1 COGs: COG1286 membrane protein required for colicin V production; InterPro IPR003825; KEGG: dat:HRM2_35760 colicin V production protein-like protein; PFAM: Colicin V production, CvpA; SPTR: colicin V production protein-like protein; PFAM: Colicin V production protein YP_004371617.1 KEGG: fjo:Fjoh_2813 O-antigen polymerase; SPTR: Tetratricopeptide repeat family YP_004371618.1 KEGG: adg:Adeg_0058 transcription termination factor Rho; SPTR: Singapore isolate B (sub-type 7) whole genome shotgun sequence assembly, scaffold_6 YP_004371619.1 COGs: COG0207 Thymidylate synthase; KEGG: tpe:Tpen_0948 thymidylate synthase-like; SPTR: Thymidylate synthase-like protein; PFAM: Thymidylate synthase YP_004371620.1 COGs: COG2250 conserved hypothetical protein related to C-terminal domain of eukaryotic chaperone SACSIN; InterPro IPR007842; KEGG: sua:Saut_2008 HEPN domain-containing protein; PFAM: HEPN; SMART: HEPN; SPTR: HEPN domain protein; PFAM: HEPN domain YP_004371621.1 InterPro IPR002934; KEGG: rca:Rcas_4127 hypothetical protein; PFAM: nucleotidyl transferase domain; SPTR: uncharacterized protein; PFAM: nucleotidyltransferase domain YP_004371622.1 KEGG: efa:EF0425 5-keto-4-deoxyuronate isomerase; SPTR: uncharacterized protein YP_004371623.1 KEGG: cyt:cce_3133 hypothetical protein; SPTR: Plasmid stabilization system; TIGRFAM: addiction module toxin, RelE/StbE family YP_004371624.1 KEGG: mar:MAE_61720 hypothetical protein; SPTR: uncharacterized protein YP_004371625.1 COGs: COG0638 20S proteasome alpha and beta subunits; InterPro IPR001353; KEGG: mgi:Mflv_2743 hypothetical protein; PFAM: Proteasome, subunit alpha/beta; SPTR: Proteasome endopeptidase complex; PFAM: Proteasome subunit YP_004371626.1 COGs: COG1117 ABC-type phosphate transport system ATPase component; InterPro IPR003439:IPR005670:IPR003593; KEGG: tjr:TherJR_2127 phosphate ABC transporter, ATPase subunit; PFAM: ABC transporter-like; PRIAM: phosphate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: phosphate ABC transporter, ATPase subunit; TIGRFAM: phosphate transport system permease 1; PFAM: ABC transporter; TIGRFAM: phosphate ABC transporter, ATP-binding protein YP_004371627.1 COGs: COG1117 ABC-type phosphate transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: adg:Adeg_1013 phosphate ABC transporter, ATPase subunit; PFAM: ABC transporter-like; PRIAM: phosphate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: phosphate ABC transporter, ATPase subunit; PFAM: ABC transporter; TIGRFAM: phosphate ABC transporter, ATP-binding protein YP_004371628.1 COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR000515:IPR005672; KEGG: cpy:Cphy_1669 phosphate ABC transporter, inner membrane subunit PstA; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: phosphate ABC transporter, inner membrane subunit PstA; TIGRFAM: phosphate transport system permease 2; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease PstA YP_004371629.1 COGs: COG0573 ABC-type phosphate transport system permease component; InterPro IPR000515:IPR011864; KEGG: cpy:Cphy_1668 phosphate ABC transporter, inner membrane subunit PstC; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: phosphate ABC transporter, inner membrane subunit PstC; TIGRFAM: phosphate ABC transporter, permease PstC; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease PstC; phosphate ABC transporter, permease PstA YP_004371630.1 COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR011862; KEGG: cpy:Cphy_1667 phosphate binding protein; SPTR: phosphate binding protein; TIGRFAM: phosphate binding protein; TIGRFAM: phosphate binding protein YP_004371631.1 COGs: COG0704 phosphate uptake regulator; InterPro IPR008170; KEGG: gme:Gmet_2705 phosphate uptake regulator, PhoU; PFAM: PhoU; SPTR: phosphate uptake regulator, PhoU; TIGRFAM: PhoU; PFAM: PhoU domain; TIGRFAM: phosphate transport system regulatory protein PhoU YP_004371632.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: pca:Pcar_0653 two-component response regulator PhoB; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Two-component response regulator PhoB; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal YP_004371633.1 COGs: COG5002 Signal transduction histidine kinase; InterProIPR003660:IPR013767:IPR003661:IPR003594:IPR 000014; KEGG: pca:Pcar_0654 two-component sensor histidine kinase PhoR; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; PAS fold; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; PAS; SPTR: PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004371634.1 COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR006059:IPR005673; KEGG: azl:AZL_e02450 phosphate transport system substrate-binding protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: ABC transporter phosphate-binding protein; TIGRFAM: Periplasmic phosphate binding protein; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: phosphate ABC transporter, phosphate-binding protein YP_004371635.1 COGs: COG0573 ABC-type phosphate transport system permease component; InterPro IPR000515:IPR011864; KEGG: azl:AZL_e02440 phosphate transport system permease; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: phosphate transport system permease; TIGRFAM: phosphate ABC transporter, permease PstC; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease PstC YP_004371636.1 COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR000515:IPR005672; KEGG: avi:Avi_2831 phosphate ABC transporter permease; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: ABC-type phosphate transport system, permease component; TIGRFAM: phosphate transport system permease 2; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease PstA YP_004371637.1 COGs: COG1117 ABC-type phosphate transport system ATPase component; InterPro IPR003439:IPR005670:IPR003593; KEGG: afr:AFE_1439 phosphate ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: phosphate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: phosphate ABC transporter, ATPase subunit; TIGRFAM: phosphate transport system permease 1; PFAM: ABC transporter; TIGRFAM: phosphate ABC transporter, ATP-binding protein YP_004371638.1 COGs: COG0704 phosphate uptake regulator; InterPro IPR008170; KEGG: pca:Pcar_0659 negative regulator for pho regulon and enzyme in phosphate metabolism; PFAM: PhoU; SPTR: phosphate transport system regulatory protein PhoU; TIGRFAM: PhoU; PFAM: PhoU domain; TIGRFAM: phosphate transport system regulatory protein PhoU YP_004371639.1 COGs: COG1206 NAD(FAD)-utilizing enzyme possibly involved in translation; HAMAP: Folate-dependent ribothymidyl synthase; InterPro IPR004417:IPR002218; KEGG: dak:DaAHT2_0429 gid protein; PFAM: glucose-inhibited division protein A-related; PRIAM:methylenetetrahydrofolate--tRNA-(uracil-5-)-m ethyltransferase(FADH(2)-oxidizing); SPTR:methylenetetrahydrofolate--tRNA-(uracil-5-)-me thyltransferasetrmFO; TIGRFAM: Folate-dependent ribothymidyl synthase; PFAM: glucose inhibited division protein A; TIGRFAM: tRNA:m(5)U-54 methyltransferase YP_004371640.1 COGs: COG0550 Topoisomerase IA; InterProIPR006171:IPR013497:IPR013498:IPR005733:IPR 003601:IPR003602; KEGG: dak:DaAHT2_2318 DNA topoisomerase I; PFAM: DNA topoisomerase, type IA, central; Toprim domain; DNA topoisomerase, type IA, zn finger; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain; SPTR: DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial-type; PFAM: Toprim domain; Topoisomerase DNA binding C4 zinc finger; DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial YP_004371641.1 COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR000445:IPR003488; KEGG: gme:Gmet_0890 smf protein; PFAM: DNA recombination-mediator protein A; Helix-hairpin-helix motif; SPTR: SMF protein; TIGRFAM: DNA recombination-mediator protein A; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA YP_004371642.1 KEGG: dol:Dole_1575 hypothetical protein; SPTR: uncharacterized protein; PFAM: Dynamin family YP_004371643.1 COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: gur:Gura_1717 preprotein translocase, YajC subunit; PFAM: Preprotein translocase YajC; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: Preprotein translocase YajC; PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit YP_004371644.1 COGs: COG0343 Queuine/archaeosine tRNA-ribosyltransferase; HAMAP: Queuine tRNA-ribosyltransferase; InterPro IPR004803:IPR002616; KEGG: gme:Gmet_0852 queuine tRNA-ribosyltransferase; PFAM: Queuine/other tRNA-ribosyltransferase; PRIAM: tRNA-guanine transglycosylase; SPTR: Queuine tRNA-ribosyltransferase 1; TIGRFAM: Queuine tRNA-ribosyltransferase; Queuine/other tRNA-ribosyltransferase; PFAM: Queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylases, various specificities; tRNA-guanine transglycosylase, queuosine-34-forming YP_004371645.1 COGs: COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); HAMAP: Queuosine biosynthesis protein; InterPro IPR003699; KEGG: dak:DaAHT2_0258 S-adenosylmethionine/tRNA-ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; SPTR: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 2; TIGRFAM: Queuosine biosynthesis protein; PFAM: Queuosine biosynthesis protein; TIGRFAM: S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_004371646.1 KEGG: ame:409879 similar to CG12139-PB; SPTR: GI20703 YP_004371647.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: sat:SYN_02671 pleiotrophic regulatory protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Pleiotrophic regulatory protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase YP_004371648.1 KEGG: sad:SAAV_0525 SdrD protein; SPTR: Ser-Asp rich fibrinogen/bone sialoprotein-binding protein SdrD YP_004371649.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: gct:GC56T3_3173 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase YP_004371650.1 COGs: COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis; InterPro IPR003856; KEGG: cvi:CV_0772 hypothetical protein; PFAM: Lipopolysaccharide biosynthesis; SPTR: uncharacterized protein; PFAM: Chain length determinant protein YP_004371651.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: nwa:Nwat_2846 sugar transferase; PFAM: Bacterial sugar transferase; SPTR: Sugar transferase; PFAM: Bacterial sugar transferase YP_004371652.1 COGs: COG1208 nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835; KEGG: sat:SYN_01129 mannose-1-phosphate guanyltransferase; PFAM: nucleotidyl transferase; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: glucose-1-phosphate adenylyltransferase; PFAM: nucleotidyl transferase YP_004371653.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: sfu:Sfum_2184 polysaccharide biosynthesis protein CapD; PFAM: polysaccharide biosynthesis protein CapD-like; SPTR: polysaccharide biosynthesis protein CapD; PFAM: polysaccharide biosynthesis protein YP_004371654.1 COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: sfu:Sfum_2192 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-sulfoquinovose synthase; SPTR: UDP-sulfoquinovose synthase; PFAM: NAD dependent epimerase/dehydratase YP_004371655.1 InterPro IPR002797; KEGG: sti:Sthe_2764 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein YP_004371656.1 KEGG: vsp:VS_0220 hypothetical protein; SPTR: uncharacterized protein YP_004371657.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: mem:Memar_1595 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase YP_004371658.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: mem:Memar_1604 glycosyl transferase, group 1; PFAM: glycosyl transferase, group 1; SPTR: glycosyl transferase, group 1; PFAM: glycosyl transferases group 1 YP_004371659.1 KEGG: pth:PTH_1110 hypothetical protein; SPTR: uncharacterized protein YP_004371660.1 COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR000583:IPR001962:IPR006426; KEGG: mem:Memar_2057 asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; glutamine amidotransferase, class-II; PRIAM: Asparagine synthase (glutamine-hydrolyzing); SPTR: Asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing) YP_004371661.1 InterPro IPR000182; KEGG: lin:lin2246 hypothetical protein; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Predicted protein; PFAM: Acetyltransferase (GNAT) family YP_004371662.1 COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: mrb:Mrub_0360 glycosyl transferase group 1; PFAM: glycosyl transferase, group 1; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1 YP_004371663.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: dbr:Deba_2275 radical SAM protein; PFAM: Radical SAM; SPTR: radical SAM protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM additional 4Fe4S-binding domain YP_004371664.1 KEGG: dbr:Deba_2273 hypothetical protein; SPTR: uncharacterized protein YP_004371665.1 COGs: COG2267 Lysophospholipase; InterPro IPR000073; KEGG: sfu:Sfum_2845 temperature sensitive supressor-like; PFAM: Alpha/beta hydrolase fold-1; SPTR: Temperature sensitive supressor-like YP_004371666.1 KEGG: dtu:Dtur_0360 peptidase C45 acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; SPTR: peptidase C45 acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; PFAM: acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase YP_004371667.1 COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: sat:SYN_00608 oligopeptide-binding protein; PFAM: Bacterial extracellular solute-binding protein, family 5; SPTR: Oligopeptide-binding protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004371668.1 COGs: COG5561 metal-binding protein; InterPro IPR014925; KEGG: dol:Dole_0580 hypothetical protein; PFAM: Uncharacterised protein domain CGGC-dom; SPTR: CGGC domain protein; PFAM: CGGC domain YP_004371669.1 COGs: COG1013 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: sfu:Sfum_1167 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: 2-oxoglutarate synthase; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain YP_004371670.1 KEGG: hmu:Hmuk_2426 hypothetical protein; SPTR: membrane-associated oxidoreductase YP_004371671.1 COGs: COG1014 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: sfu:Sfum_1168 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate/ketoisovalerate oxidoreductase, catalytic domain; PRIAM: 2-oxoglutarate synthase; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family YP_004371672.1 COGs: COG0547 Anthranilate phosphoribosyltransferase; HAMAP: Anthranilate phosphoribosyl transferase; InterPro IPR005940:IPR017459:IPR000312; KEGG: gur:Gura_1733 anthranilate phosphoribosyltransferase; PFAM: glycosyl transferase, family 3; glycosyl transferase, family 3, N-terminal; PRIAM: Anthranilate phosphoribosyltransferase; SPTR: Anthranilate phosphoribosyltransferase; TIGRFAM: Anthranilate phosphoribosyl transferase; PFAM: glycosyl transferase, a/b domain; glycosyl transferase, helical bundle domain; TIGRFAM: anthranilate phosphoribosyltransferase YP_004371673.1 COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: tgr:Tgr7_2798 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase YP_004371674.1 Contains selenocysteine; KEGG: dak:DaAHT2_1610 DsrE family protein; SPTR: DsrE family protein; manually curated; PFAM: DsrE/DsrF-like family YP_004371675.1 COGs: COG0135 phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: gme:Gmet_2492 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); SPTR: N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase YP_004371676.1 COGs: COG0133 Tryptophan synthase beta chain; HAMAP: Tryptophan synthase beta chain/beta chain-like; InterPro IPR023026:IPR001926:IPR006654; KEGG: gsu:GSU2375 tryptophan synthase, beta subunit; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Tryptophan synthase; SPTR: Tryptophan synthase beta chain 1; TIGRFAM: Tryptophan synthase, beta chain; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: tryptophan synthase, beta subunit YP_004371677.1 COGs: COG0159 Tryptophan synthase alpha chain; HAMAP: Tryptophan synthase, alpha chain; InterPro IPR002028; KEGG: gur:Gura_3280 tryptophan synthase subunit alpha; PFAM: Tryptophan synthase, alpha chain; PRIAM: Tryptophan synthase; SPTR: Tryptophan synthase alpha chain; TIGRFAM: Tryptophan synthase, alpha chain; PFAM: Tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, alpha subunit YP_004371678.1 KEGG: rfr:Rfer_2762 protein tyrosine phosphatase, receptor type, F-like; SPTR: protein tyrosine phosphatase, receptor type, F-like YP_004371679.1 COGs: COG0813 Purine-nucleoside phosphorylase; InterPro IPR000845; KEGG: sfu:Sfum_1429 purine phosphorylases family protein 1; PFAM: nucleoside phosphorylase domain; SPTR: phosphorylase; PFAM: phosphorylase superfamily YP_004371680.1 COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; InterPro IPR001279; KEGG: dat:HRM2_37440 hypothetical protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Metallo-beta-lactamase; PFAM: Metallo-beta-lactamase superfamily YP_004371681.1 COGs: COG0703 shikimate kinase; HAMAP: shikimate kinase; InterPro IPR000623; KEGG: dal:Dalk_1763 shikimate kinase; PFAM: shikimate kinase; PRIAM: shikimate kinase; SPTR: shikimate kinase 1; PFAM: shikimate kinase YP_004371682.1 COGs: COG0082 Chorismate synthase; InterPro IPR000453; KEGG: dak:DaAHT2_2093 chorismate synthase; PFAM: Chorismate synthase; PRIAM: Chorismate synthase; SPTR: Chorismate synthase; TIGRFAM: Chorismate synthase; PFAM: Chorismate synthase; TIGRFAM: chorismate synthase YP_004371683.1 COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: sat:SYN_01933 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; PRIAM: Chorismate mutase; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase YP_004371684.1 COGs: COG0172 seryl-tRNA synthetase; HAMAP: seryl-tRNA synthetase, class IIa; InterPro IPR002317:IPR015866:IPR002314; KEGG: tye:THEYE_A0018 seryl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; seryl-tRNA synthetase, class IIa, N-terminal; PRIAM: Serine--tRNA ligase; SPTR: seryl-tRNA synthetase; TIGRFAM: seryl-tRNA synthetase, class IIa; PFAM: seryl-tRNA synthetase N-terminal domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: seryl-tRNA synthetase YP_004371685.1 KEGG: dol:Dole_1195 hypothetical protein; SPTR: Uncharacterized protein involved in formation of curli polymers-like protein YP_004371686.1 KEGG: geo:Geob_0198 hypothetical protein; SPTR: uncharacterized protein YP_004371687.1 KEGG: gme:Gmet_3303 hypothetical protein; SPTR: uncharacterized protein YP_004371689.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: bss:BSUW23_05850 murein lytic transglycosylase; PFAM: Lytic transglycosylase-like, catalytic; SPTR: murein lytic transglycosylase; PFAM: transglycosylase SLT domain YP_004371690.1 COGs: COG0628 permease; InterPro IPR002549; KEGG: dbr:Deba_1546 protein of unknown function UPF0118; PFAM: Uncharacterised protein family UPF0118; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF20 YP_004371691.1 KEGG: gvi:gll2284 hypothetical protein; SPTR: Gll2284 protein YP_004371692.1 COGs: COG2121 conserved hypothetical protein; InterPro IPR007172; KEGG: sfu:Sfum_1638 hypothetical protein; PFAM: Domain of unknown function DUF374; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF374) YP_004371693.1 InterPro IPR018961; KEGG: sfu:Sfum_2138 hypothetical protein; PFAM: DnaJ homologue, subfamily C, member 28, conserved domain; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1992) YP_004371694.1 COGs: COG0422 Thiamine biosynthesis protein ThiC; HAMAP: Thiamine biosynthesis protein ThiC; InterPro IPR002817; KEGG: tjr:TherJR_0725 thiamine biosynthesis protein ThiC; PFAM: Thiamine biosynthesis protein ThiC; SPTR: phosphomethylpyrimidine synthase 3; TIGRFAM: Thiamine biosynthesis protein ThiC; PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC YP_004371695.1 COGs: COG0586 membrane-associated protein; InterPro IPR015414; KEGG: sfu:Sfum_0454 hypothetical protein; PFAM: hypothetical protein; SPTR: uncharacterized protein; PFAM: hypothetical protein YP_004371696.1 COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR015977:IPR006405; KEGG: sfu:Sfum_2602 nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; SPTR: Nicotinate phosphoribosyltransferase; TIGRFAM: Nicotinate phosphoribosyltransferase PFAM: Nicotinate phosphoribosyltransferase (NAPRTase) family; TIGRFAM: nicotinate phosphoribosyltransferase YP_004371697.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149:IPR020843; KEGG: drm:Dred_3256 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, C-terminal; PRIAM: L-iditol 2-dehydrogenase; SMART: polyketide synthase, enoylreductase; SPTR: Alcohol dehydrogenase, zinc-containing; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004371698.1 COGs: COG0547 Anthranilate phosphoribosyltransferase; InterPro IPR017459:IPR000312:IPR005940; KEGG: cpc:Cpar_0870 anthranilate phosphoribosyltransferase; PFAM: glycosyl transferase, family 3; glycosyl transferase, family 3, N-terminal; PRIAM: Anthranilate phosphoribosyltransferase; SPTR: Anthranilate phosphoribosyltransferase; TIGRFAM: Anthranilate phosphoribosyl transferase; PFAM: glycosyl transferase, a/b domain; glycosyl transferase, helical bundle domain; TIGRFAM: anthranilate phosphoribosyltransferase YP_004371699.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR002078:IPR002197:IPR003593; KEGG: mxa:MXAN_0172 sigma-54 dependent DNA-binding response regulator; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: Sigma-54 dependent DNA-binding response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004371700.1 COGs: COG3158 K+ transporter; HAMAP: Potassium uptake protein, low affinity, Kup; InterPro IPR023051:IPR003855; KEGG: dvm:DvMF_0985 K potassium transporter; PFAM: K+ potassium transporter; SPTR: Potassium transporter; PFAM: K+ potassium transporter; TIGRFAM: potassium uptake protein YP_004371701.1 COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR003852:IPR006016; KEGG: mxa:MXAN_0167 osmosensitive K+ channel histidine kinase sensor subunit; PFAM: Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal; UspA; SPTR: Sensor protein KdpD; PFAM: Universal stress protein family; Osmosensitive K+ channel His kinase sensor domain YP_004371702.1 COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003660:IPR013656:IPR003661:IPR003594; KEGG: mxa:MXAN_0168 sensory box histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Sensory box histidine kinase; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004371703.1 KEGG: pla:Plav_2540 hypothetical protein; SPTR: uncharacterized protein YP_004371704.1 COGs: COG0296 1 4-alpha-glucan branching enzyme; HAMAP: 1,4-alpha-glucan-branching enzyme; InterProIPR006407:IPR004193:IPR006047:IPR006048:IPR 006589; KEGG: tro:trd_1933 1,4-alpha-glucan branching enzyme; PFAM: Alpha-amylase, C-terminal all beta; glycoside hydrolase, family 13, N-terminal; glycosyl hydrolase, family 13, catalytic domain; PRIAM: 1,4-alpha-glucan branching enzyme; SMART: glycosyl hydrolase, family 13, subfamily, catalytic domain; SPTR: 1,4-alpha-glucan-branching enzyme; TIGRFAM: 1,4-alpha-glucan-branching enzyme; PFAM: Alpha amylase, C-terminal all-beta domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; TIGRFAM: alpha-1,4-glucan:alpha-1,4-glucan 6-glycosyltransferase YP_004371705.1 COGs: COG1734 DnaK suppressor protein; InterPro IPR000962; KEGG: gur:Gura_1290 TraR/DksA family transcriptional regulator; SPTR: TraR/DksA family transcriptional regulator; PFAM: Prokaryotic dksA/traR C4-type zinc finger; TIGRFAM: RNA polymerase-binding protein DksA YP_004371706.1 COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR007127:IPR009042:IPR007627:IPR007624:IPR 007630:IPR014284; KEGG: dak:DaAHT2_1066 RNA polymerase, sigma 70 subunit, RpoD subfamily; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 1.2; RNA polymerase sigma factor 70, region 1.1; RNA polymerase sigma-70 region 3; RNA polymerase sigma-70 region 4; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-70; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 factor, region 1.1; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004371707.1 COGs: COG3481 HD-superfamily hydrolase; InterPro IPR004365:IPR006674:IPR006675:IPR003607; KEGG: sat:SYN_02192 HD-superfamily hydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; Nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: HD-superfamily hydrolase; TIGRFAM: Uncharacterised protein family HDIG; PFAM: HD domain; OB-fold nucleic acid binding domain; TIGRFAM: uncharacterized domain HDIG YP_004371708.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: dly:Dehly_0155 UspA domain-containing protein; PFAM: UspA; SPTR: UspA domain protein; PFAM: Universal stress protein family YP_004371709.1 COGs: COG3494 conserved hypothetical protein; InterPro IPR010415; KEGG: sfu:Sfum_3750 hypothetical protein; PFAM: protein of unknown function DUF1009; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1009) YP_004371710.1 COGs: COG1043 acyl-(acyl carrier protein); HAMAP:acyl-[acyl-carrier-protein]--UDP-N-acetylgluc osamineO-acyltransferase; InterPro IPR010137:IPR001451; KEGG: dal:Dalk_1791 acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase; PRIAM:acyl-[acyl-carrier-protein]--UDP-N-acetylgluc osamineO-acyltransferase; SPTR:acyl-[acyl-carrier-protein]--UDP-N-acetylgluco samineO-acyltransferase; TIGRFAM:acyl-[acyl-carrier-protein]--UDP-N-acetylgl ucosamineO-acyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase YP_004371711.1 COGs: COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; HAMAP: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; InterPro IPR010084:IPR013114; KEGG: dsa:Desal_2521 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; SPTR: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; TIGRFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; PFAM: FabA-like domain; TIGRFAM: beta-hydroxyacyl-[acyl carrier protein] dehydratase FabZ YP_004371712.1 COGs: COG1044 UDP-3-O-(3-hydroxymyristoyl); HAMAP: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; InterPro IPR007691:IPR020573:IPR001451; KEGG: gme:Gmet_2355 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; PFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region; Bacterial transferase hexapeptide repeat; SPTR: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; PFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Bacterial transferase hexapeptide (three repeats); TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_004371713.1 COGs: COG2825 Outer membrane protein; InterPro IPR005632; KEGG: bba:Bd1494 hypothetical protein; PFAM: Outer membrane chaperone Skp (OmpH); SMART: Outer membrane chaperone Skp (OmpH); SPTR: exported protein; PFAM: Outer membrane protein (OmpH-like) YP_004371714.1 COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184:IPR016474; KEGG: dbr:Deba_2109 outer membrane protein assembly complex, YaeT protein; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Outer membrane protein assembly complex, YaeT protein; TIGRFAM: Outer membrane assembly protein, YaeT; PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein YP_004371715.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: dal:Dalk_1786 ABC transporter related; PFAM: ABC transporter-like; PRIAM: phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter YP_004371716.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838:IPR011925; KEGG: sfu:Sfum_3743 LolC/E family lipoprotein releasing system, transmembrane protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Lipoprotein releasing system, transmembrane protein, LolC/E family; TIGRFAM: Lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: Predicted permease; TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family YP_004371717.1 COGs: COG1190 lysyl-tRNA synthetase (class II); HAMAP: lysyl-tRNA synthetase, class II; InterPro IPR002313:IPR004365:IPR004364; KEGG: dak:DaAHT2_1306 lysyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: Lysine--tRNA ligase; SPTR: lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase, class II; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial YP_004371718.1 KEGG: tad:TRIADDRAFT_57912 hypothetical protein; SPTR: uncharacterized protein YP_004371719.1 KEGG: vcn:VOLCADRAFT_92322 hypothetical protein; SPTR: uncharacterized protein YP_004371720.1 COGs: COG2406 protein distantly related to ferritins; InterPro IPR008331; KEGG: dbr:Deba_0016 ferritin Dps family protein; PFAM: Ferritin/Dps protein; SPTR: Ferritin Dps family protein; PFAM: Ferritin-like domain YP_004371721.1 COGs: COG5557 polysulphide reductase; InterPro IPR005614; KEGG: sfu:Sfum_1150 polysulphide reductase, NrfD; PFAM: polysulphide reductase, NrfD; SPTR: uncharacterized protein; PFAM: polysulphide reductase, NrfD YP_004371722.1 COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR001450:IPR006311; KEGG: dsy:DSY0315 Hdr-like menaquinol oxidoreductase iron-sulfur subunit 1 precursor; PFAM: 4Fe-4S binding domain; SPTR: Hdr-like menaquinol oxidoreductase iron-sulfur subunit 1; PFAM: 4Fe-4S binding domain YP_004371723.1 KEGG: mta:Moth_1605 cytochrome c family protein; SPTR: Cytochrome c family protein YP_004371724.1 COGs: COG0247 Fe-S oxidoreductase; KEGG: mta:Moth_1606 4Fe-4S ferredoxin, iron-sulfur binding; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding YP_004371725.1 COGs: COG2181 nitrate reductase gamma subunit; InterPro IPR003816; KEGG: sfu:Sfum_1146 nitrate reductase, gamma subunit; PFAM: nitrate reductase, gamma subunit; SPTR: nitrate reductase, gamma subunit; PFAM: nitrate reductase gamma subunit YP_004371726.1 KEGG: sfu:Sfum_1145 hypothetical protein; SPTR: uncharacterized protein YP_004371728.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: drt:Dret_1146 UspA domain protein; PFAM: UspA; SPTR: UspA domain protein; PFAM: Universal stress protein family YP_004371729.1 InterPro IPR001450; KEGG: dal:Dalk_4380 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain YP_004371730.1 COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: sfu:Sfum_4039 peptidylprolyl isomerase, FKBP-type; PFAM: peptidyl-prolyl cis-trans isomerase, FKBP-type; SPTR: peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase YP_004371731.1 COGs: COG1042 acyl-CoA synthetase (NDP forming); InterPro IPR003781:IPR000182; KEGG: dat:HRM2_37830 SucC4; PFAM: CoA-binding; GCN5-related N-acetyltransferase (GNAT) domain; SMART: CoA-binding; SPTR: acetyl coenzyme A synthetase (ADP forming), alpha domain protein; PFAM: CoA binding domain; Acetyltransferase (GNAT) family; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain YP_004371732.1 COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182; KEGG: gbm:Gbem_2443 acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: N-acetylglutamate synthase; PFAM: Acetyltransferase (GNAT) family YP_004371733.1 COGs: COG0653 Preprotein translocase subunit SecA (ATPase RNA helicase); HAMAP: SecA protein; InterProIPR000185:IPR011115:IPR011130:IPR001650:IPR 011116:IPR004027; KEGG: sfu:Sfum_1202 preprotein translocase, SecA subunit; PFAM: SecA DEAD-like, N-terminal; SecA preprotein, cross-linking domain; Helicase, C-terminal; SecA Wing/Scaffold; SEC-C motif; SMART: SecA DEAD-like, N-terminal; SecA preprotein, cross-linking domain; SPTR: protein translocase subunit secA; TIGRFAM: SecA protein; PFAM: SecA DEAD-like domain; SecA preprotein cross-linking domain; SEC-C motif; SecA Wing and Scaffold domain; TIGRFAM: preprotein translocase, SecA subunit YP_004371734.1 COGs: COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase); HAMAP: arginine biosynthesis protein ArgJ; InterPro IPR002813; KEGG: gur:Gura_1795 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase; PFAM: arginine biosynthesis protein ArgJ; PRIAM: Amino-acid N-acetyltransferase; SPTR: arginine biosynthesis bifunctional protein ArgJ; TIGRFAM: arginine biosynthesis protein ArgJ; PFAM: ArgJ family; TIGRFAM: glutamate N-acetyltransferase/amino-acid acetyltransferase YP_004371735.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254:IPR001440:IPR013105:IPR019734; KEGG: cpc:Cpar_1378 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR-1; peptidase S1/S6, chymotrypsin/Hap; Tetratricopeptide TPR2; SMART: Tetratricopeptide repeat; SPTR: TPR repeat:Tetratricopeptide TPR_4; PFAM: Trypsin; Tetratricopeptide repeat YP_004371736.1 KEGG: pfa:PFD0630c erythrocyte membrane protein 1, PfEMP1; SPTR: Erythrocyte membrane protein 1, PfEMP1 YP_004371737.1 KEGG: tko:TK2154 hypothetical protein YP_004371738.1 KEGG: dbr:Deba_0683 hypothetical protein; SPTR: uncharacterized protein YP_004371739.1 COGs: COG0767 ABC-type transport system involved in resistance to organic solvents permease component; InterPro IPR002645:IPR003453; KEGG: dbr:Deba_0592 protein of unknown function DUF140; PFAM: Domain of unknown function DUF140; Sulphate transporter/antisigma-factor antagonist STAS; SPTR: uncharacterized protein; TIGRFAM: Domain of unknown function DUF140; PFAM: Domain of unknown function DUF140; STAS domain; TIGRFAM: anti-anti-sigma factor; conserved hypothetical integral membrane protein YP_004371740.1 COGs: COG1127 ABC-type transport system involved in resistance to organic solvents ATPase component; InterPro IPR003439:IPR003593; KEGG: dbr:Deba_0591 ABC transporter; PFAM: ABC transporter-like; PRIAM: sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter; PFAM: ABC transporter YP_004371741.1 COGs: COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: dbr:Deba_0590 mammalian cell entry related domain protein; PFAM: Mammalian cell entry-related; SPTR: uncharacterized protein; PFAM: mce related protein YP_004371742.1 InterPro IPR005586; KEGG: dbr:Deba_0589 protein of unknown function DUF330; PFAM: protein of unknown function DUF330; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF330) YP_004371743.1 COGs: COG3605 Signal transduction protein containing GAF and PtsI domains; InterPro IPR003018; KEGG: sfu:Sfum_3729 GAF sensor protein; PFAM: GAF; SMART: GAF; SPTR: GAF sensor protein; PFAM: GAF domain YP_004371744.1 COGs: COG0148 Enolase; HAMAP: Enolase; InterPro IPR000941:IPR020811:IPR020810; KEGG: tai:Taci_0321 enolase; PFAM: Enolase, C-terminal; Enolase, N-terminal; PRIAM: phosphopyruvate hydratase; SPTR: Enolase; TIGRFAM: Enolase; PFAM: Enolase, N-terminal domain; Enolase, C-terminal TIM barrel domain; TIGRFAM: phosphopyruvate hydratase YP_004371745.1 InterPro IPR011701; KEGG: slp:Slip_2339 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004371746.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: tro:trd_1976 UspA; PFAM: UspA; SPTR: UspA; PFAM: Universal stress protein family YP_004371747.1 COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006153; KEGG: tro:trd_1977 Kef-type K+ transport systems, membrane components; PFAM: Cation/H+ exchanger; SPTR: Kef-type K+ transport systems, membrane components; PFAM: Sodium/hydrogen exchanger family YP_004371748.1 COGs: COG2524 transcriptional regulator protein; InterPro IPR003793:IPR000644; KEGG: dol:Dole_2980 signal transduction protein; PFAM: cystathionine beta-synthase, core; Domain of unknown function DUF190; SMART: cystathionine beta-synthase, core; SPTR: signal transduction protein with CBS domains; PFAM: CBS domain; Uncharacterized ACR, COG1993 YP_004371749.1 COGs: COG0239 Integral membrane protein possibly involved in chromosome condensation; HAMAP: Camphor resistance CrcB protein; InterPro IPR003691; KEGG: dol:Dole_2979 camphor resistance protein CrcB; PFAM: Camphor resistance CrcB protein; SPTR: protein CrcB homolog; TIGRFAM: Camphor resistance CrcB protein; PFAM: CrcB-like protein; TIGRFAM: crcB protein YP_004371750.1 InterPro IPR001401; KEGG: sfu:Sfum_2910 dynamin family protein; PFAM: Dynamin, GTPase domain; SPTR: Dynamin family protein; PFAM: Dynamin family YP_004371751.1 KEGG: sfu:Sfum_2374 hypothetical protein; SPTR: uncharacterized protein YP_004371752.1 KEGG: sfu:Sfum_2374 hypothetical protein; SPTR: uncharacterized protein YP_004371753.1 COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: tjr:TherJR_1313 phosphoglycerate mutase; PFAM: histidine phosphatase superfamily, clade-1; SMART: histidine phosphatase superfamily, clade-1; SPTR: phosphoglycerate mutase; PFAM: phosphoglycerate mutase YP_004371754.1 COGs: COG0013 Alanyl-tRNA synthetase; InterPro IPR018164:IPR012947:IPR003156:IPR002318; KEGG: pca:Pcar_2408 alanyl-tRNA synthetase; PFAM: Alanyl-tRNA synthetase, class IIc, N-terminal; Threonyl/alanyl tRNA synthetase, SAD; phosphoesterase, DHHA1; SMART: Threonyl/alanyl tRNA synthetase, SAD; SPTR: Alanyl-tRNA synthetase; TIGRFAM: Alanyl-tRNA synthetase, class IIc; PFAM: DHHA1 domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A); TIGRFAM: alanine--tRNA ligase YP_004371755.1 COGs: COG0468 RecA/RadA recombinase; HAMAP: DNA recombination and repair protein RecA; InterPro IPR013765:IPR003593; KEGG: sat:SYN_02028 RecA protein; PFAM: DNA recombination and repair protein RecA; SMART: ATPase, AAA+ type, core; SPTR: protein recA; TIGRFAM: DNA recombination and repair protein RecA; PFAM: recA bacterial DNA recombination protein; TIGRFAM: protein RecA YP_004371756.1 COGs: COG1514 2'-5' RNA ligase; InterPro IPR014051:IPR004175; KEGG: sfu:Sfum_2529 2'-5' RNA ligase; PFAM: phosphoesterase, HXTX; SPTR: 2'-5' RNA ligase; TIGRFAM: 2',5' RNA ligase; PFAM: 2',5' RNA ligase; TIGRFAM: 2'-5' RNA ligase YP_004371757.1 COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: dbr:Deba_1143 competence/damage-inducible protein CinA; PFAM: CinA, C-terminal; Molybdopterin binding; SMART: Molybdopterin binding; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: Competence-induced protein CinA; CinA, C-terminal; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain YP_004371758.1 COGs: COG1267 phosphatidylglycerophosphatase A and related protein; InterPro IPR007686; KEGG: dak:DaAHT2_0362 phosphatidylglycerophosphatase A; PFAM: phosphatidylglycerophosphatase A; SPTR: phosphatidylglycerophosphatase A; PFAM: phosphatidylglycerophosphatase A YP_004371759.1 COGs: COG0815 Apolipoprotein N-acyltransferase; HAMAP: Apolipoprotein N-acyltransferase; InterPro IPR004563:IPR003010; KEGG: dal:Dalk_1559 apolipoprotein N-acyltransferase; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Apolipoprotein N-acyltransferase; TIGRFAM: Apolipoprotein N-acyltransferase; PFAM: Carbon-nitrogen hydrolase; TIGRFAM: apolipoprotein N-acyltransferase YP_004371760.1 COGs: COG1159 GTPase; HAMAP: GTP-binding protein Era; InterPro IPR005662:IPR002917:IPR004044:IPR005225; KEGG: tye:THEYE_A0343 GTP-binding protein Era; PFAM: GTP-binding protein, HSR1-related; K Homology, type 2; SPTR: GTP-binding protein era homolog; TIGRFAM: GTP-binding protein Era; Small GTP-binding protein; PFAM: KH domain; GTPase of unknown function; TIGRFAM: GTP-binding protein Era; small GTP-binding protein domain YP_004371761.1 KEGG: dat:HRM2_12090 hypothetical protein; SPTR: uncharacterized protein YP_004371762.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: ppd:Ppro_3646 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004371763.1 COGs: COG0626 cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: sfu:Sfum_2670 cystathionine gamma-synthase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: cystathionine gamma-lyase; SPTR: cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme YP_004371764.1 KEGG: gem:GM21_0275 nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Nucleic acid binding OB-fold tRNA/helicase-type YP_004371765.1 KEGG: pfr:PFREUD_09330 hypothetical protein; SPTR: uncharacterized protein YP_004371766.1 KEGG: aca:ACP_2749 hypothetical protein; SPTR: uncharacterized protein YP_004371767.1 KEGG: mta:Moth_2363 transmembrane transcriptional regulator (anti-sigma factor); SPTR: transmembrane transcriptional regulator (Anti-sigma factor); TIGRFAM: anti-sigma factor, TIGR02949 family YP_004371768.1 COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: dal:Dalk_3684 heat shock protein HSP20; PFAM: Heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family YP_004371769.1 COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: sfu:Sfum_1742 heat shock protein HSP20; PFAM: Heat shock protein Hsp20; SPTR: Hsp20/alpha crystallin family protein; PFAM: Hsp20/alpha crystallin family YP_004371770.1 COGs: COG2131 Deoxycytidylate deaminase; InterPro IPR002125; KEGG: cyc:PCC7424_0712 CMP/dCMP deaminase zinc-binding; PFAM: CMP/dCMP deaminase, zinc-binding; SPTR: cytidine/deoxycytidylate deaminase; manually curated; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_004371771.1 COGs: COG0557 Exoribonuclease R; InterProIPR013223:IPR001900:IPR003029:IPR011805:IPR 004476:IPR011129:IPR022967; KEGG: gsu:GSU1485 ribonuclease R; PFAM: ribonuclease II/R; ribonuclease B, N-terminal OB domain; ribosomal protein S1, RNA-binding domain; SMART: ribonuclease II/R; Cold shock protein; RNA-binding domain, S1; SPTR: ribonuclease R, ; TIGRFAM: ribonuclease R, bacterial; ribonuclease II/ribonuclease R, bacteria; PFAM: ribonuclease B OB domain; RNB domain; S1 RNA binding domain; TIGRFAM: ribonuclease R; VacB and RNase II family 3'-5' exoribonucleases YP_004371772.1 KEGG: cin:100182732 similar to FH2 domain containing 1 YP_004371773.1 KEGG: dma:DMR_31490 flagellar hook-associated protein 3; SPTR: Flagellar hook-associated protein 3 YP_004371774.1 COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR000477:IPR002729; KEGG: adg:Adeg_1767 CRISPR-associated protein Cas1; PFAM: CRISPR-associated protein Cas1; Reverse transcriptase; SPTR: CRISPR-associated protein Cas1; TIGRFAM: CRISPR-associated protein Cas1; PFAM: Group II intron, maturase-specific domain; Reverse transcriptase (RNA-dependent DNA polymerase); CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated endonuclease Cas1 YP_004371775.1 KEGG: nph:NP3856A hypothetical protein; SPTR: uncharacterized protein YP_004371776.1 KEGG: abo:ABO_0908 capsular polysaccharide biosynthesis protein/UDP-glucose dehydrogenase/GDP mannose family protein, putati; SPTR: Two-component sensor histidine kinase YP_004371777.1 KEGG: cag:Cagg_1065 hypothetical protein; SPTR: uncharacterized protein; PFAM: RAMP superfamily; TIGRFAM: CRISPR-associated protein YP_004371778.1 KEGG: nfa:nfa29320 hypothetical protein; SPTR: uncharacterized protein YP_004371779.1 COGs: COG4006 conserved hypothetical protein; InterPro IPR013442; KEGG: ttm:Tthe_0939 CRISPR-associated protein, APE2256 family; PFAM: CRISPR-associated protein APE2256; SPTR: CRISPR-associated protein, APE2256 family; TIGRFAM: CRISPR-associated protein APE2256; PFAM: CRISPR-associated protein (Cas_APE2256); TIGRFAM: CRISPR-associated protein, APE2256 family YP_004371780.1 InterPro IPR005537; KEGG: bts:Btus_2244 cold-shock DNA-binding domain protein; PFAM: protein of unknown function DUF324; SPTR: Cold-shock DNA-binding domain protein; PFAM: RAMP superfamily; TIGRFAM: CRISPR-associated protein YP_004371781.1 KEGG: cel:W06H8.8 TiTiN family member (ttn-1); SPTR: 2MDa_1 protein YP_004371782.1 COGs: COG1337 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR005537; KEGG: dau:Daud_1800 hypothetical protein; PFAM: protein of unknown function DUF324; SPTR: uncharacterized protein; PFAM: RAMP superfamily YP_004371783.1 COGs: COG1337 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR005537:IPR013411; KEGG: dau:Daud_1801 CRISPR-associated Csm3 family protein; PFAM: protein of unknown function DUF324; SPTR: CRISPR-associated RAMP protein, SSO1426 family; TIGRFAM: CRISPR-associated RAMP TM1809; PFAM: RAMP superfamily; TIGRFAM: CRISPR-associated RAMP protein, SSO1426 family YP_004371784.1 KEGG: mmx:MmarC6_1579 glycosyl transferase; SPTR: aspartate-semialdehyde dehydrogenase YP_004371785.1 KEGG: cya:CYA_0880 CRISPR-associated RAMP Csx10 family protein; SPTR: CRISPR-associated RAMP protein, Csx10 family; TIGRFAM: CRISPR-associated RAMP protein, Csx10 family YP_004371786.1 COGs: COG1337 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR005537; KEGG: adg:Adeg_0981 protein of unknown function DUF324; PFAM: protein of unknown function DUF324; SPTR: uncharacterized protein; PFAM: RAMP superfamily YP_004371787.1 COGs: COG1353 hydrolase of the HD superfamily (permuted catalytic motifs); KEGG: lba:Lebu_1069 hypothetical protein; SPTR: uncharacterized protein YP_004371788.1 KEGG: vvi:100256335 hypothetical protein LOC100256335; SPTR: Possible TonB-dependent receptor YP_004371789.1 COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR001667:IPR003156:IPR004610; KEGG: drm:Dred_0731 single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ-like; phosphoesterase, DHHA1; SPTR: Single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: Bacterial RecJ exonuclease; PFAM: DHH family; DHHA1 domain; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ YP_004371790.1 COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; HAMAP: Uncharacterised protein family UPF0173, metal-dependent hydrolase; InterPro IPR001279:IPR022877; KEGG: ttr:Tter_0760 beta-lactamase domain protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: UPF0173 metal-dependent hydrolase Tter_0760; PFAM: Metallo-beta-lactamase superfamily YP_004371791.1 COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR013099:IPR003148:IPR006037; KEGG: gbm:Gbem_3794 TrkA domain-containing protein; PFAM: Regulator of K+ conductance, N-terminal; Ion transport 2; Regulator of K+ conductance, C-terminal; SPTR: TrkA-N domain protein; PFAM: TrkA-N domain; Ion channel; TrkA-C domain YP_004371792.1 KEGG: bbt:BBta_4202 N-acetylmuramoyl-L-alanine amidase; SPTR: N-acetylmuramoyl-L-alanine amidase YP_004371793.1 InterPro IPR011467; KEGG: sfu:Sfum_3060 hypothetical protein; PFAM: protein of unknown function DUF1573; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1573) YP_004371794.1 COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; HAMAP: Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807; KEGG: sfu:Sfum_4004 imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase YP_004371795.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594; KEGG: tye:THEYE_A0747 sensor histidine kinase, PFAM: ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; SPTR: Response regulator receiver domain protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004371796.1 COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789:IPR006674:IPR003607; KEGG: dbr:Deba_2013 response regulator receiver modulated metal dependent phosphohydrolase; PFAM: Signal transduction response regulator, receiver domain; Metal-dependent phosphohydrolase, HD subdomain; SMART: Signal transduction response regulator, receiver domain; Metal-dependent phosphohydrolase, HD domain; SPTR: Response regulator receiver modulated metal dependent phosphohydrolase; PFAM: HD domain; Response regulator receiver domain YP_004371797.1 COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: sfu:Sfum_1223 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Carboxyl transferase; PFAM: Carboxyl transferase domain YP_004371798.1 KEGG: dal:Dalk_3781 hypothetical protein; SPTR: uncharacterized protein YP_004371799.1 COGs: COG5016 pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891:IPR003379:IPR000089; KEGG: dly:Dehly_0355 carboxylase-domain containing protein; PFAM: Carboxylase, conserved domain; pyruvate carboxyltransferase; Biotin/lipoyl attachment; PRIAM: pyruvate carboxylase; SPTR: pyruvate carboxylase subunit B; PFAM: HMGL-like; Biotin-requiring enzyme; Conserved carboxylase domain YP_004371800.1 COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873:IPR006163:IPR002123; KEGG: aae:aq_999 long-chain-fatty-acid CoA ligase; PFAM: AMP-dependent synthetase/ligase; phosphopantetheine-binding; phospholipid/glycerol acyltransferase; PRIAM: Long-chain-fatty-acid--CoA ligase., 1-acylglycerol-3-phosphate O-acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: Long-chain-fatty-acid CoA ligase; PFAM: phosphopantetheine attachment site; acyltransferase; AMP-binding enzyme; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; acyl carrier protein YP_004371801.1 COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR003594:IPR000182; KEGG: cpb:Cphamn1_0760 anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATPase-like, ATP-binding domain; GCN5-related N-acetyltransferase (GNAT) domain; SPTR: anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004371802.1 KEGG: dbr:Deba_1545 hypothetical protein; SPTR: uncharacterized protein YP_004371803.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: cli:Clim_1282 outer membrane efflux protein; PFAM: Outer membrane efflux protein; SPTR: Outer membrane efflux protein; PFAM: Outer membrane efflux protein YP_004371804.1 COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: cli:Clim_1281 efflux transporter, RND family, MFP subunit; PFAM: Secretion protein HlyD; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004371805.1 InterPro IPR003838; KEGG: cli:Clim_1280 protein of unknown function DUF214; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004371806.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: cli:Clim_1279 ABC transporter related; PFAM: ABC transporter-like; PRIAM: phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter YP_004371807.1 COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099:IPR001763; KEGG: gme:Gmet_3484 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain YP_004371808.1 COGs: COG3746 phosphate-selective porin; InterPro IPR010870; KEGG: psl:Psta_4368 phosphate-selective porin O and P; PFAM: phosphate-selective porin O/P; SPTR: phosphate-selective porin O and P; PFAM: phosphate-selective porin O and P YP_004371809.1 KEGG: sfu:Sfum_3603 hypothetical protein; SPTR: uncharacterized protein YP_004371810.1 KEGG: ppd:Ppro_1979 hypothetical protein; SPTR: uncharacterized protein YP_004371811.1 KEGG: ppd:Ppro_2233 17 kDa surface antigen; SPTR: Lipoprotein YP_004371812.1 COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341:IPR013342; KEGG: ttu:TERTU_4393 O-succinylbenzoate-CoA synthase; PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal; Mandelate racemase/muconate lactonizing enzyme, N-terminal; SMART: Mandelate racemase/muconate lactonizing enzyme, C-terminal; SPTR: O-succinylbenzoate-CoA synthase; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain YP_004371813.1 COGs: COG0223 methionyl-tRNA formyltransferase; InterPro IPR002376:IPR005793; KEGG: gme:Gmet_0884 formyltransferase; PFAM: formyl transferase, N-terminal; formyl transferase, C-terminal; PRIAM: methionyl-tRNA formyltransferase; SPTR: bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; PFAM: formyl transferase; formyl transferase, C-terminal domain YP_004371814.1 COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: gme:Gmet_0883 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase YP_004371815.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: geo:Geob_1547 polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: polysaccharide deacetylase; PFAM: polysaccharide deacetylase YP_004371816.1 COGs: COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; HAMAP: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; InterPro IPR001228; KEGG: sat:SYN_01401 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_004371817.1 COGs: COG0245 2C-methyl-D-erythritol 2 4-cyclodiphosphate synthase; HAMAP: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core; InterPro IPR003526; KEGG: tjr:TherJR_0254 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core; SPTR: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; TIGRFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core; PFAM: YgbB family; TIGRFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_004371818.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: slp:Slip_2063 radical SAM protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: radical SAM protein; PFAM: Radical SAM superfamily YP_004371819.1 COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR005110:IPR001453:IPR005111:IPR020817; KEGG: pth:PTH_2617 molybdopterin biosynthesis enzyme; PFAM: MoeA, N-terminal and linker domain; Molybdopterin binding; MoeA, C-terminal, domain IV; SMART: Molybdopterin binding; SPTR: Molybdopterin biosynthesis enzyme; TIGRFAM: Molybdenum cofactor synthesis; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain YP_004371820.1 KEGG: cyc:PCC7424_0315 hypothetical protein; SPTR: uncharacterized protein YP_004371821.1 InterPro IPR012753; KEGG: mar:MAE_10540 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: Addiction module toxin, RelE/StbE; manually curated YP_004371822.1 KEGG: gur:Gura_1849 hypothetical protein; SPTR: uncharacterized protein YP_004371823.1 COGs: COG2801 transposase and inactivated derivatives; InterPro IPR001584; KEGG: gur:Gura_1848 integrase catalytic subunit; PFAM: Integrase, catalytic core; SPTR: Integrase, catalytic region; PFAM: Integrase core domain YP_004371824.1 KEGG: dat:HRM2_29590 transposase (11 DDE domain protein); SPTR: transposase (11 DDE domain protein) YP_004371825.1 InterPro IPR019636; KEGG: hmo:HM1_3129 hypothetical protein; PFAM: Cell wall-associated hydrolase; SPTR: uncharacterized protein; manually curated; PFAM: Cell wall-associated hydrolase YP_004371826.1 KEGG: ana:asr4470 hypothetical protein; SPTR: uncharacterized protein YP_004371827.1 KEGG: cyt:cce_3133 hypothetical protein; SPTR: uncharacterized protein YP_004371828.1 COGs: COG2217 Cation transport ATPase; InterPro IPR008250:IPR005834:IPR006416:IPR001757; KEGG: gym:GYMC10_6092 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Haloacid dehalogenase-like hydrolase; PRIAM: Copper-exporting ATPase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_004371829.1 COGs: COG2217 Cation transport ATPase; InterProIPR008250:IPR005834:IPR006404:IPR006416:IPR 001757; KEGG: dbr:Deba_1134 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Haloacid dehalogenase-like hydrolase; PRIAM: Cadmium-exporting ATPase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004371830.1 COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: dal:Dalk_2586 protein of unknown function DUF156; PFAM: protein of unknown function DUF156; SPTR: uncharacterized protein; PFAM: Uncharacterised BCR, COG1937 YP_004371831.1 COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: phe:Phep_0225 enoyl-CoA hydratase/isomerase; PFAM: Crotonase, core; SPTR: enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isomerase YP_004371833.1 COGs: COG0481 Membrane GTPase LepA; HAMAP: GTP-binding protein LepA; InterProIPR000795:IPR004161:IPR000640:IPR013842:IPR 006297:IPR005225; KEGG: sfu:Sfum_1361 GTP-binding protein LepA; PFAM: protein synthesis factor, GTP-binding; translation elongation factor EFTu/EF1A, domain 2; translation elongation factor EFG/EF2, C-terminal; GTP-binding protein LepA, C-terminal; SPTR: GTP-binding protein lepA; TIGRFAM: GTP-binding protein LepA; Small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; GTP-binding protein LepA C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein domain YP_004371834.1 COGs: COG0863 DNA modification methylase; InterPro IPR002941; KEGG: tth:TTC0041 methyltransferase; PFAM: DNA methylase N-4/N-6; SPTR: methyltransferase; PFAM: DNA methylase YP_004371835.1 KEGG: pmg:P9301_18791 aspartyl-tRNA synthetase; SPTR: pyruvate, phosphate dikinase YP_004371836.1 InterPro IPR007712; KEGG: bgl:bglu_1g12000 hypothetical protein; PFAM: Plasmid stabilisation system; SPTR: uncharacterized protein; PFAM: Plasmid stabilisation system protein YP_004371837.1 KEGG: swo:Swol_0981 hypothetical protein; SPTR: uncharacterized protein YP_004371838.1 InterPro IPR013509:IPR000788:IPR013344; KEGG: sfu:Sfum_0259 ribonucleotide-diphosphate reductase subunit alpha; PFAM: ribonucleotide reductase large subunit, C-terminal; ribonucleotide reductase large subunit, N-terminal; PRIAM: ribonucleoside-diphosphate reductase; SPTR: ribonucleoside-diphosphate reductase; TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: ribonucleotide reductase, all-alpha domain; ribonucleotide reductase, barrel domain; TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent YP_004371839.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: phe:Phep_0981 alpha/beta hydrolase fold protein; PFAM: Alpha/beta hydrolase fold-1; SPTR: Alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold YP_004371840.1 COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: gur:Gura_1147 secretion protein HlyD family protein; PFAM: Secretion protein HlyD; SPTR: Efflux pump, RND family, membrane fusion protein; PFAM: HlyD family secretion protein YP_004371841.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: gme:Gmet_0658 ABC transporter-related protein; PFAM: ABC transporter-like; PRIAM: sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter YP_004371842.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: gur:Gura_1149 ABC transporter related; PFAM: ABC transporter-like; PRIAM: sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related; PFAM: ABC transporter YP_004371843.1 COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: ppd:Ppro_2906 ABC transporter; PFAM: ABC transporter; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004371844.1 COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: sus:Acid_5992 ABC transporter; PFAM: ABC transporter; SPTR: ABC transporter; PFAM: ABC transporter YP_004371845.1 COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: dbr:Deba_2097 glycosyl transferase 2; PFAM: glycosyl transferase, family 2; SPTR: glycosyl transferase 2; PFAM: glycosyl transferase 2 YP_004371846.1 COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: sfu:Sfum_1209 hypothetical protein; PFAM: protein of unknown function DUF164; SPTR: uncharacterized protein; PFAM: zinc ribbon domain YP_004371847.1 COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: toc:Toce_0935 protein of unknown function DUF34; PFAM: NGG1p interacting factor 3, NIF3; SPTR: uncharacterized protein; TIGRFAM: NGG1p interacting factor 3, NIF3; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family YP_004371848.1 COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR009042:IPR007627:IPR007624:IPR007630:IPR 014284:IPR012760; KEGG: sfu:Sfum_1212 RpoD family RNA polymerase sigma factor; PFAM: RNA polymerase sigma-70 region 3; RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 1.2; RNA polymerase sigma-70 region 4; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor RpoD, C-terminal; RNA polymerase sigma-70; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma factor RpoD, C-terminal domain YP_004371849.1 COGs: COG0358 DNA primase; InterPro IPR002694:IPR013264:IPR006171:IPR006295; KEGG: dal:Dalk_3077 DNA primase; PFAM: DNA primase, catalytic core, N-terminal; Zinc finger, CHC2-type; Toprim domain; SPTR: DNA primase; TIGRFAM: DNA primase, DnaG; PFAM: DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; TIGRFAM: DNA primase, catalytic core YP_004371850.1 COGs: COG1193 Mismatch repair ATPase (MutS family); HAMAP: DNA mismatch repair protein MutS, type 2; InterPro IPR000432:IPR002625:IPR005747:IPR007696; KEGG: pca:Pcar_2680 mismatch repair ATPase; PFAM: Smr protein/MutS2 C-terminal; DNA mismatch repair protein MutS, C-terminal; SMART: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, core; Smr protein/MutS2 C-terminal; SPTR: Mismatch repair ATPase (MutS family); TIGRFAM: DNA mismatch repair protein MutS, type 2; PFAM: MutS domain V; Smr domain; TIGRFAM: MutS2 family protein YP_004371851.1 COGs: COG1610 conserved hypothetical protein; InterPro IPR019004; KEGG: tma:TM0690 hypothetical protein; SPTR: uncharacterized protein; PFAM: Yqey-like protein YP_004371852.1 HAMAP: ribosomal protein S21; InterPro IPR001911; KEGG: glo:Glov_1016 30S ribosomal protein S21; PFAM: ribosomal protein S21; SPTR: 30S ribosomal protein S21; TIGRFAM: ribosomal protein S21; PFAM: ribosomal protein S21; TIGRFAM: ribosomal protein S21 YP_004371853.1 COGs: COG2454 conserved hypothetical protein; InterPro IPR007368; KEGG: dbr:Deba_0364 protein of unknown function DUF434; PFAM: protein of unknown function DUF434; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF434) YP_004371854.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623:IPR002939; KEGG: ppd:Ppro_0013 chaperone DnaJ domain-containing protein; PFAM: Chaperone DnaJ, C-terminal; Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: uncharacterized protein; PFAM: DnaJ C terminal region; DnaJ domain YP_004371855.1 KEGG: dal:Dalk_0943 hypothetical protein; SPTR: uncharacterized protein YP_004371856.1 COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR013196:IPR004143:IPR003142:IPR004408; KEGG: sth:STH1400 transcriptional repressor, BirA-like; PFAM: Biotin/lipoate A/B protein ligase; Helix-turn-helix, type 11; Biotin protein ligase, C-terminal; PRIAM: Biotin--[acetyl-CoA-carboxylase] ligase; SPTR: transcriptional repressor, BirA-like; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; PFAM: HTH domain; Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region; BirA biotin operon repressor domain YP_004371857.1 KEGG: azl:AZL_a09060 hypothetical protein; SPTR: uncharacterized protein YP_004371858.1 KEGG: ppf:Pput_0751 hypothetical protein; SPTR: uncharacterized protein YP_004371859.1 COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: sat:SYN_01342 oligopeptide transport system permease; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Oligopeptide transport system permease; PFAM: Binding-protein-dependent transport system inner membrane component YP_004371860.1 COGs: COG1875 ATPase related to phosphate starvation-inducible protein PhoH; InterPro IPR003714:IPR006596; KEGG: dal:Dalk_3397 PhoH family protein; PFAM: PhoH-like protein; SMART: nucleotide binding protein, PINc; SPTR: PhoH family protein; PFAM: PhoH-like protein YP_004371861.1 InterPro IPR003427; KEGG: bfs:BF1421 histidine decarboxylase; PFAM: Pyruvoyl-dependent histidine decarboxylase, PI chain; PRIAM: histidine decarboxylase; SPTR: histidine decarboxylase; PFAM: histidine carboxylase PI chain YP_004371862.1 KEGG: aap:NT05HA_1796 SmpA protein; SPTR: SmpA protein; PFAM: SmpA / OmlA family YP_004371863.1 COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR003018:IPR013767:IPR003661:IPR003594:IPR 000014:IPR001610; KEGG: dbr:Deba_0269 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; GAF; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; GAF; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS; PFAM: GAF domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box YP_004371864.1 KEGG: dap:Dacet_0463 hypothetical protein; SPTR: uncharacterized protein; PFAM: F0F1-ATPase subunit (ATPase_gene1) YP_004371865.1 KEGG: gsu:GSU0335 hypothetical protein; SPTR: uncharacterized protein; PFAM: ATP synthase I chain YP_004371866.1 COGs: COG0356 F0F1-type ATP synthase subunit a; HAMAP: ATPase, F0 complex, subunit A; InterPro IPR000568; KEGG: dbr:Deba_2726 ATP synthase F0, A subunit; PFAM: ATPase, F0 complex, subunit A; SPTR: ATP synthase F0, A subunit; TIGRFAM: ATPase, F0 complex, subunit A; PFAM: ATP synthase A chain; TIGRFAM: ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes) YP_004371867.1 HAMAP: ATPase, F0 complex, subunit C; InterPro IPR002379:IPR000454:IPR005953; KEGG: dbr:Deba_2727 ATP synthase F0, C subunit; PFAM: ATPase, F0/V0 complex, subunit C; SPTR: ATP synthase F0, C subunit; TIGRFAM: ATPase, F0 complex, subunit C, bacterial/chloroplast; PFAM: ATP synthase subunit C; TIGRFAM: ATP synthase, F0 subunit c YP_004371868.1 COGs: COG2344 AT-rich DNA-binding protein; HAMAP: transcriptional repressor, redox-sensing, Rex; InterPro IPR009718:IPR003781:IPR022876; KEGG: sfu:Sfum_1603 redox-sensing transcriptional repressor REX; PFAM: CoA-binding; Rex DNA-binding, C-terminal; SMART: CoA-binding; SPTR: Redox-sensing transcriptional repressor rex; PFAM: CoA binding domain; DNA-binding protein N-terminus YP_004371869.1 COGs: COG0178 Excinuclease ATPase subunit; HAMAP: Excinuclease ABC, A subunit; InterPro IPR003439:IPR004602:IPR003593; KEGG: pca:Pcar_0087 excinuclease ABC, A subunit; PFAM: ABC transporter-like; SPTR: Excinuclease ABC subunit A; TIGRFAM: Excinuclease ABC, A subunit; PFAM: ABC transporter; TIGRFAM: excinuclease ABC, A subunit YP_004371870.1 COGs: COG0508 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; KEGG: gme:Gmet_2511 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding; PRIAM: dihydrolipoyllysine-residue acetyltransferase; SPTR: pyruvate dehydrogenase complex E2 component, dihydrolipoamide acetyltransferase; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme YP_004371871.1 KEGG: afr:AFE_0522 peptidyl-prolyl cis-trans isomerase, PPIC-type; SPTR: peptidyl-prolyl cis-trans isomerase, PPIC-type YP_004371872.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR002078:IPR002197:IPR003593; KEGG: dal:Dalk_0661 two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004371873.1 KEGG: sat:SYN_02040 cytoplasmic protein; SPTR: Hypothetical cytosolic protein YP_004371874.1 KEGG: dya:Dyak_GE23151 GE23151 gene product from transcript GE23151-RA; SPTR: GE23151 YP_004371875.1 KEGG: dma:DMR_37280 zinc resistance-associated protein precursor; SPTR: uncharacterized protein YP_004371876.1 COGs: COG0068 Hydrogenase maturation factor; InterPro IPR001792:IPR011125:IPR006070:IPR004421; KEGG: sro:Sros_3809 (NiFe) hydrogenase maturation protein HypF; PFAM: Sua5/YciO/YrdC, N-terminal; acylphosphatase-like; Zinc finger, HypF-type; SPTR: (NiFe) hydrogenase maturation protein HypF; TIGRFAM: Carbamoyltransferase, HypF-type; PFAM: HypF finger; yrdC domain; acylphosphatase; TIGRFAM: [NiFe] hydrogenase maturation protein HypF YP_004371877.1 COGs: COG0298 Hydrogenase maturation factor; InterPro IPR001109; KEGG: dat:HRM2_11590 HypC; PFAM: Hydrogenase expression/formation protein, HupF/HypC; SPTR: HypC; TIGRFAM: Hydrogenase expression/formation protein, HupF/HypC; PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF YP_004371878.1 COGs: COG0409 Hydrogenase maturation factor; InterPro IPR002780; KEGG: sfu:Sfum_4014 hydrogenase expression/formation protein HypD; PFAM: Hydrogenase formation HypD protein; SPTR: Hydrogenase expression/formation protein HypD; TIGRFAM: Hydrogenase formation HypD protein; PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD YP_004371879.1 KEGG: brm:Bmur_0805 thioredoxin domain protein; SPTR: Cytochrome c biogenesis protein transmembrane region; PFAM: protein of unknown function, DUF255 YP_004371880.1 InterPro IPR011701; KEGG: tjr:TherJR_0520 drug resistance transporter, EmrB/QacA subfamily; PFAM: Major facilitator superfamily MFS-1; SPTR: Drug resistance transporter, EmrB/QacA subfamily; manually curated; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily YP_004371881.1 COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR001967; KEGG: dak:DaAHT2_1678 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; SPTR: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; PFAM: D-alanyl-D-alanine carboxypeptidase YP_004371882.1 KEGG: tgo:TGME49_003010 protein kinase, SPTR: Serine/threonine-protein kinase YP_004371883.1 COGs: COG1490 D-Tyr-tRNAtyr deacylase; HAMAP: D-tyrosyl-tRNA(Tyr) deacylase; InterPro IPR003732; KEGG: taf:THA_1655 D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-tyrosyl-tRNA(Tyr) deacylase; SPTR: D-tyrosyl-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-Tyr-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase YP_004371884.1 COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: gsu:GSU3374 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase; TIGRFAM: ribulose-phosphate 3-epimerase YP_004371885.1 COGs: COG2518 protein-L-isoaspartate carboxylmethyltransferase; HAMAP: protein-L-isoaspartate(D-aspartate) O-methyltransferase; InterPro IPR000682; KEGG: gur:Gura_3331 protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; PRIAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; SPTR: protein-L-isoaspartate O-methyltransferase 3; TIGRFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); TIGRFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_004371886.1 COGs: COG3409 peptidoglycan-binding domain-containing protein; InterPro IPR003709:IPR002477; KEGG: azo:azo3973 hypothetical protein; PFAM: peptidoglycan binding-like; peptidase M15B/M15C, D,D-carboxypeptidase VanY/endolysins; SPTR: uncharacterized protein; PFAM: peptidoglycan binding domain; D-alanyl-D-alanine carboxypeptidase YP_004371887.1 COGs: COG0058 glucan phosphorylase; InterPro IPR000811:IPR011833; KEGG: sfu:Sfum_2957 glycogen/starch/alpha-glucan phosphorylases; PFAM: glycosyl transferase, family 35; SPTR: phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: Carbohydrate phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylases YP_004371888.1 COGs: COG0205 6-phosphofructokinase; InterPro IPR000023; KEGG: sfu:Sfum_2958 diphosphate--fructose-6-phosphate 1-phosphotransferase; PFAM: phosphofructokinase domain; PRIAM: 6-phosphofructokinase; SPTR: 6-phosphofructokinase; PFAM: phosphofructokinase YP_004371889.1 COGs: COG0060 Isoleucyl-tRNA synthetase; HAMAP: Isoleucyl-tRNA synthetase, class Ia; InterPro IPR002300:IPR013155:IPR010663:IPR002301; KEGG: gur:Gura_4313 isoleucyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ia; Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; Zinc finger, DNA glycosylase/AP lyase/isoleucyl tRNA synthetase; PRIAM: Isoleucine--tRNA ligase; SPTR: Isoleucyl-tRNA synthetase; TIGRFAM: Isoleucyl-tRNA synthetase, class Ia; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Zinc finger found in FPG and IleRS; TIGRFAM: isoleucyl-tRNA synthetase YP_004371890.1 COGs: COG0597 Lipoprotein signal peptidase; HAMAP: peptidase A8, signal peptidase II; InterPro IPR001872; KEGG: dak:DaAHT2_1177 lipoprotein signal peptidase; PFAM: peptidase A8, signal peptidase II; SPTR: Lipoprotein signal peptidase; TIGRFAM: peptidase A8, signal peptidase II; PFAM: Signal peptidase (SPase) II; TIGRFAM: lipoprotein signal peptidase YP_004371891.1 COGs: COG0682 Prolipoprotein diacylglyceryltransferase; HAMAP: Prolipoprotein diacylglyceryl transferase; InterPro IPR001640; KEGG: dol:Dole_1189 prolipoprotein diacylglyceryl transferase; PFAM: Prolipoprotein diacylglyceryl transferase; SPTR: uncharacterized protein; TIGRFAM: Prolipoprotein diacylglyceryl transferase; PFAM: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase YP_004371893.1 COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: dol:Dole_0479 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: uncharacterized protein; PFAM: Cytidylyltransferase YP_004371894.1 COGs: COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; HAMAP: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; InterPro IPR013512:IPR013644:IPR003821; KEGG: pca:Pcar_1915 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal; 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal; PRIAM: 1-deoxy-D-xylulose-5-phosphate reductoisomerase; SPTR: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_004371895.1 COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR008915:IPR001478:IPR004387; KEGG: dak:DaAHT2_0974 membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF; SPTR: Membrane-associated zinc metalloprotease; TIGRFAM: peptidase M50, membrane-associated zinc metallopeptidase; PFAM: peptidase M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP YP_004371896.1 InterPro IPR013096; KEGG: reh:H16_A1583 hypothetical protein; PFAM: Cupin 2, conserved barrel; SPTR: uncharacterized protein; PFAM: Cupin domain YP_004371897.1 COGs: COG0816 endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); HAMAP: Resolvase, holliday junction-type, YqgF-like; InterPro IPR005227:IPR006641; KEGG: mta:Moth_1640 Holliday junction resolvase YqgF; PFAM: Resolvase, holliday junction-type, YqgF-like; SMART: Resolvase, RNase H-like fold; SPTR: Holliday junction resolvase; TIGRFAM: Resolvase, holliday junction-type, YqgF-like; PFAM: Uncharacterised protein family (UPF0081); TIGRFAM: RNAse H-fold protein YqgF YP_004371898.1 KEGG: gme:Gmet_1025 hypothetical protein; SPTR: uncharacterized protein YP_004371899.1 InterPro IPR013078; KEGG: rsl:RPSI07_1533 conserved hypothethical protein; PFAM: histidine phosphatase superfamily, clade-1; SPTR: uncharacterized protein YP_004371900.1 COGs: COG1801 conserved hypothetical protein; InterPro IPR002763; KEGG: ank:AnaeK_0458 protein of unknown function DUF72; PFAM: protein of unknown function DUF72; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF72 YP_004371901.1 COGs: COG0066 3-isopropylmalate dehydratase small subunit; HAMAP: 3-isopropylmalate dehydratase small subunit; InterPro IPR000573:IPR011827; KEGG: pth:PTH_0533 3-isopropylmalate dehydratase small subunit; PFAM: Aconitase A/isopropylmalate dehydratase small subunit, swivel; PRIAM: (R)-2-methylmalate dehydratase; SPTR: 3-isopropylmalate dehydratase small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit, subgroup; PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit YP_004371902.1 COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR001804; KEGG: tye:THEYE_A0114 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; PRIAM: 3-isopropylmalate dehydrogenase; SPTR: 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase YP_004371903.1 COGs: COG0136 aspartate-semialdehyde dehydrogenase; InterPro IPR000534:IPR012280:IPR005986; KEGG: sat:SYN_00911 aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD-binding; PRIAM: aspartate-semialdehyde dehydrogenase; SMART: Semialdehyde dehydrogenase, NAD-binding; SPTR: aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase, bacterial; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: aspartate-semialdehyde dehydrogenase (peptidoglycan organisms) YP_004371905.1 COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398; KEGG: scl:sce8059 methylase; PFAM: RNA methyltransferase, RsmD; SPTR: methylase; TIGRFAM: RNA methyltransferase, RsmD; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family YP_004371906.1 COGs: COG0669 phosphopantetheine adenylyltransferase; HAMAP: Coenzyme A biosynthesis protein; InterPro IPR004820:IPR001980:IPR004821; KEGG: sat:SYN_00909 phosphopantetheine adenylyltransferase; PFAM: Cytidylyltransferase; PRIAM: Pantetheine-phosphate adenylyltransferase; SPTR: phosphopantetheine adenylyltransferase; TIGRFAM: Coenzyme A biosynthesis protein; Cytidyltransferase-related; PFAM: Cytidylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase, bacterial; cytidyltransferase-related domain YP_004371907.1 KEGG: bxe:Bxe_B2116 hypothetical protein; SPTR: uncharacterized protein YP_004371908.1 COGs: COG1205 Distinct helicase with a unique C-terminal domain including a metal-binding cysteine cluster; InterPro IPR011545:IPR001650:IPR018973:IPR014001; KEGG: sfu:Sfum_1698 DEAD/DEAH box helicase domain-containing protein; PFAM: protein of unknown function DUF1998; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: DEAD/DEAH box helicase; PFAM: Helicase conserved C-terminal domain; Domain of unknown function (DUF1998); DEAD/DEAH box helicase YP_004371909.1 COGs: COG0322 Nuclease subunit of the excinuclease complex; HAMAP: Excinuclease ABC, C subunit; InterPro IPR000305:IPR001943:IPR001162:IPR004791; KEGG: sfu:Sfum_1257 excinuclease ABC, C subunit; PFAM: Excinuclease ABC, C subunit, C-terminal; Excinuclease ABC, C subunit, N-terminal; UvrB/UvrC protein; SMART: Excinuclease ABC, C subunit, N-terminal; SPTR: UvrABC system protein C; TIGRFAM: Excinuclease ABC, C subunit; PFAM: UvrB/uvrC motif; UvrC Helix-hairpin-helix N-terminal; GIY-YIG catalytic domain; TIGRFAM: excinuclease ABC, C subunit YP_004371910.1 COGs: COG0020 Undecaprenyl pyrophosphate synthase; HAMAP:Di-trans-poly-cis-decaprenylcistransferase-li ke; InterPro IPR001441; KEGG: mta:Moth_1038 undecaprenyl pyrophosphate synthetase; PFAM:Di-trans-poly-cis-decaprenylcistransferase-lik e; PRIAM: Di-trans,poly-cis-decaprenylcistransferase; SPTR: Di-trans,poly-cis-decaprenylcistransferase; TIGRFAM:Di-trans-poly-cis-decaprenylcistransferase- like; PFAM: undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase YP_004371911.1 COGs: COG0233 ribosome recycling factor; HAMAP: ribosome recycling factor, bacterial-like; InterPro IPR002661:IPR015998; KEGG: dal:Dalk_3162 ribosome recycling factor; PFAM: ribosome recycling factor; SPTR: ribosome-recycling factor; TIGRFAM: ribosome recycling factor; PFAM: ribosome recycling factor; TIGRFAM: ribosome recycling factor YP_004371912.1 COGs: COG0528 Uridylate kinase; InterPro IPR001048:IPR015963; KEGG: gur:Gura_3731 uridylate kinase; PFAM: aspartate/glutamate/uridylate kinase; SPTR: Uridylate kinase; TIGRFAM: Uridylate kinase, bacteria; PFAM: Amino acid kinase; TIGRFAM: uridylate kinase YP_004371913.1 COGs: COG0264 translation elongation factor Ts; HAMAP: translation elongation factor EFTs/EF1B; InterPro IPR000449:IPR014039:IPR001816; KEGG: adg:Adeg_0579 translation elongation factor Ts; PFAM: translation elongation factor EFTs/EF1B, dimerisation; Ubiquitin-associated/translation elongation factor EF1B, N-terminal; SPTR: Elongation factor Ts; TIGRFAM: translation elongation factor EFTs/EF1B; PFAM: Elongation factor TS; UBA/TS-N domain; TIGRFAM: translation elongation factor Ts YP_004371914.1 COGs: COG0052 ribosomal protein S2; InterPro IPR001865:IPR005706; KEGG: geo:Geob_1522 30S ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacteria/mitochondria/plastid; PFAM: ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type YP_004371915.1 InterPro IPR018990; KEGG: ddc:Dd586_2417 proteinase inhibitor I42, chagasin; PFAM: proteinase inhibitor I42, chagasin; SPTR: proteinase inhibitor I42, chagasin; PFAM: Chagasin family peptidase inhibitor I42 YP_004371916.1 KEGG: tan:TA06615 hypothetical protein; SPTR: uncharacterized protein YP_004371917.1 KEGG: rba:RB4182 signal peptide; SPTR: uncharacterized protein YP_004371918.1 InterPro IPR001440:IPR019734; KEGG: cph:Cpha266_1841 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: TPR repeat-containing protein YP_004371919.1 KEGG: cyj:Cyan7822_2122 hypothetical protein; SPTR: uncharacterized protein YP_004371920.1 KEGG: tel:tll1523 hypothetical protein; SPTR: uncharacterized protein YP_004371921.1 KEGG: plm:Plim_0513 hypothetical protein; SPTR: uncharacterized protein; PFAM: MotA/TolQ/ExbB proton channel family YP_004371922.1 COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR014045:IPR001932; KEGG: amt:Amet_2780 protein phosphatase 2C-like protein; PFAM: protein phosphatase 2C, N-terminal; SMART: protein phosphatase 2C-like; SPTR: protein phosphatase 2C-like protein; PFAM: protein phosphatase 2C YP_004371923.1 InterPro IPR000253; KEGG: cbr:CBG19922 Hypothetical protein CBG19922; PFAM: Forkhead-associated (FHA) domain; SPTR: uncharacterized protein; PFAM: FHA domain YP_004371924.1 InterPro IPR002035:IPR000253:IPR017802; KEGG: ttr:Tter_1017 von Willebrand factor type A; type II secretion system protein; PFAM: von Willebrand factor, type A; Forkhead-associated (FHA) domain; SMART: von Willebrand factor, type A; SPTR: von Willebrand factor type A; type II secretion system protein; TIGRFAM: VWFA-related, acidobacterial-type; PFAM: von Willebrand factor type A domain; FHA domain; TIGRFAM: VWFA-related Acidobacterial domain YP_004371925.1 COGs: COG0515 Serine/threonine protein kinase; InterPro IPR017442:IPR007055:IPR002290:IPR020635; KEGG: gau:GAU_3834 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; transport-associated; PRIAM: [Myosin light-chain] kinase; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, catalytic domain; SPTR: serine/threonine protein kinase; PFAM: protein kinase domain YP_004371926.1 COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR001440:IPR013105:IPR019734; KEGG: mno:Mnod_2480 peptidase C14 caspase catalytic subunit P20; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: peptidase C14 caspase catalytic subunit p20; PFAM: Tetratricopeptide repeat YP_004371927.1 COGs: COG3287 conserved hypothetical protein; InterProIPR013702:IPR019494:IPR013655:IPR013656:IPR 003594:IPR001789:IPR000014:IPR001610; KEGG: ppd:Ppro_2089 PAS/PAC sensor hybrid histidine kinase; PFAM: FIST domain, N-terminal; FIST C domain; PAS fold-3; PAS fold-4; ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; SMART: FIST domain, N-terminal; PAS; PAC motif; ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: FIST C domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; FIST N domain; PAS fold; TIGRFAM: PAS domain S-box YP_004371928.1 COGs: COG0419 ATPase involved in DNA repair; KEGG: dma:DMR_35940 hypothetical protein; SPTR: ATPase involved in DNA repair-like protein YP_004371929.1 InterPro IPR004843; KEGG: dma:DMR_35930 hypothetical protein; PFAM: Metallo-dependent phosphatase; SPTR: Metallophosphoesterase YP_004371930.1 KEGG: dma:DMR_35920 hypothetical protein; SPTR: uncharacterized protein YP_004371931.1 KEGG: dma:DMR_35910 hypothetical protein; SPTR: uncharacterized protein YP_004371933.1 COGs: COG1598 conserved hypothetical protein; InterPro IPR005357; KEGG: pph:Ppha_0455 protein of unknown function UPF0150; PFAM: Uncharacterised protein family UPF0150; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0150) YP_004371934.1 InterPro IPR019270; KEGG: rmr:Rmar_1463 hypothetical protein; PFAM: protein of unknown function DUF2283; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2283) YP_004371935.1 KEGG: sde:Sde_0947 ribosomal protein L36; SPTR: uncharacterized protein YP_004371936.1 KEGG: dsh:Dshi_0262 hypothetical protein; SPTR: uncharacterized protein YP_004371937.1 KEGG: mba:Mbar_A3090 hypothetical protein; SPTR: uncharacterized protein YP_004371938.1 COGs: COG3549 Plasmid maintenance system killer protein; InterPro IPR007711; KEGG: nhl:Nhal_0204 plasmid maintenance system killer; PFAM: Plasmid maintenance system killer; SPTR: Plasmid maintenance system killer; PFAM: Plasmid maintenance system killer protein YP_004371939.1 COGs: COG3093 Plasmid maintenance system antidote protein; InterPro IPR001387:IPR013430; KEGG: nhl:Nhal_0203 addiction module antidote protein, HigA family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Addiction module antidote protein, HigA family; TIGRFAM: Addiction module antidote protein, HigA; PFAM: Helix-turn-helix; TIGRFAM: addiction module antidote protein, HigA family YP_004371940.1 KEGG: dal:Dalk_0032 protein of unknown function UPF0150; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0150) YP_004371941.1 COGs: COG0863 DNA modification methylase; InterPro IPR002941; KEGG: dth:DICTH_0253 m4C-methyltransferase; PFAM: DNA methylase N-4/N-6; SPTR: Type II restriction modification system, methylation subunit; PFAM: DNA methylase YP_004371942.1 InterPro IPR013099; KEGG: dma:DMR_18840 hypothetical membrane protein; PFAM: Ion transport 2; SPTR: Ion transport 2 domain protein; PFAM: Ion channel YP_004371943.1 COGs: COG1066 ATP-dependent serine protease; InterPro IPR004504:IPR003593; KEGG: gme:Gmet_3277 DNA repair protein RadA; SMART: ATPase, AAA+ type, core; SPTR: DNA repair protein radA; TIGRFAM: DNA repair protein RadA; PFAM: KaiC; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: DNA repair protein RadA YP_004371944.1 COGs: COG3876 conserved hypothetical protein; InterPro IPR008302; KEGG: dal:Dalk_0937 hypothetical protein; PFAM: Uncharacterised conserved protein UCP016719; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1343) YP_004371945.1 InterPro IPR000182; KEGG: rrs:RoseRS_4349 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family YP_004371946.1 KEGG: pop:POPTR_565731 hypothetical protein; SPTR: Predicted protein